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Sample records for agsecurity investigator vitae

  1. Writing your curriculum vitae.

    PubMed

    McKenzie, S

    2001-09-01

    Your curriculum vitae (CV) is your gateway to shortlisting. A good CV takes a long time to prepare. It should not only record your training but, more importantly, should reflect your 'physicianly' qualities, management skills and knowledge of health-care systems.

  2. Vita Genomics, Inc.

    PubMed

    Shih-Hsin Wu, Lawrence; Su, Chun-Lin; Chen, Ellson

    2007-06-01

    Vita Genomics, Inc., centered in Taiwan and China, aims to be a premier genomics-based biotechnological and biopharmaceutical company in the Asia-Pacific region. The company focuses on conducting pharmacogenomics research, in vitro diagnosis product development and specialty contract research services in both genomics and pharmacogenomics fields. We are now initiating a drug rescue program designed to resurrect drugs that have failed in the previous clinical trials owing to low efficacies. This program applies pharmacogenomics approaches using biomarkers to screen subsets of patients who may respond better or avoid adverse responses to the test drugs. Vita Genomics, Inc. has envisioned itself as an important player in the healthcare industry offering advanced molecular diagnostic products and services, revolutionizing thedrug-development process and providing pharmacogenomic solutions.

  3. The digital curriculum vitae.

    PubMed

    Galdino, Greg M; Gotway, Michael

    2005-02-01

    The curriculum vitae (CV) has been the traditional method for radiologists to illustrate their accomplishments in the field of medicine. Despite its presence in medicine as a standard, widely accepted means to describe one's professional career and its use for decades as an accomplice to most applications and interviews, there is relatively little written in the medical literature regarding the CV. Misrepresentation on medical students', residents', and fellows' applications has been reported. Using digital technology, CVs have the potential to be much more than printed words on paper and offers a solution to misrepresentation. Digital CVs may incorporate full-length articles, graphics, presentations, clinical images, and video. Common formats for digital CVs include CD-ROMs or DVD-ROMs containing articles (in Adobe Portable Document Format) and presentations (in Microsoft PowerPoint format) accompanying printed CVs, word processing documents with hyperlinks to articles and presentations either locally (on CD-ROMs or DVD-ROMs) or remotely (via the Internet), or hypertext markup language documents. Digital CVs afford the ability to provide more information that is readily accessible to those receiving and reviewing them. Articles, presentations, videos, images, and Internet links can be illustrated using standard file formats commonly available to all radiologists. They can be easily updated and distributed on an inexpensive media, such as a CD-ROM or DVD-ROM. With the availability of electronic articles, presentations, and information via the Internet, traditional paper CVs may soon be superseded by their electronic successors.

  4. Curriculum Vitae and Related Letters.

    ERIC Educational Resources Information Center

    Peterson, Sharyl Bender

    This booklet, which was developed by a college career center, explains the purpose of and procedures for writing curriculum vitae (CV) and related letters. The following topics are covered: when a CV is appropriate, points to consider when writing a CV, items usually included, possible sections to include in a CV, and steps in writing cover…

  5. An in vitro investigation to compare the surface roughness of auto glazed, reglazed and chair side polished surfaces of Ivoclar and Vita feldspathic porcelain.

    PubMed

    Sethi, Sumit; Kakade, Dilip; Jambhekar, Shantanu; Jain, Vinay

    2013-12-01

    The change in surface roughness after different surface finishing techniques has attracted the attention of several prosthodontists regarding wear of opposing teeth or restorative material and the strength; plaque retention and appearance of the restoration. However, there is considerable controversy concerning the best methods to achieve the smoothest and strongest porcelain restorations after chair side clinical adjustments. The purpose of this in vitro study was to compare the average surface roughness of a self-glazed surface, a chair side polished surface and a reglazed surface of ceramic. Two feldspathic porcelain, namely VITA VMK94 (Vita Zahnfabrik, Bad Sachingen, Germany) and IVOCLAR CLASSIC (Vivadent AG, FL-9494 Schaan, Liechtenstein) were selected to fabricate 20 specimens of each in the shape of shade guide tabs. A medium-grit diamond rotary cutting instrument was used to remove the glaze layer, and then the surface of half the specimens were re-glazed and the other half were polished using a well-defined sequence of polishing comprising of: Shofu porcelain polishing system, White gloss disc/polishing wheel, Silicone cone with diamond polishing paste and finally with small buff wheel with pumice slurry. The surface roughness (Ra) (μm) of the specimens was evaluated using a profilometer and scanning electron microscope. The data were statistically analyzed by using Student's t test. The results had shown that there is no statistically significant difference both quantitatively and qualitatively, between the surface roughness of reglazed and chair-side polished surface. In addition, both reglazed and chair-side polished surfaces are better than the autoglazed surface. Within all the groups, there is no significant difference between companies. Polishing an adjusted porcelain surface with the suggested sequence of polishing will lead to a finish similar to a re-glazed surface. Therefore chair-side polishing can be a good alternative to reglazing for

  6. A curriculum vitae: making your best impression.

    PubMed

    Harvey, C

    1993-01-01

    Describing yourself on paper is an important marketing tool for the nurse for professional opportunities today. Using a curriculum vitae (CV) serves to best illustrate relevant experiences that a nurse has had toward fulfillment of a professional objective. A readable, truthful, and polished curriculum vitae and cover letter can help nurses present themselves in a very positive manner.

  7. The "Curriculum Vitae": An Imperfect Mirror.

    ERIC Educational Resources Information Center

    Bennett, John B.

    1992-01-01

    Curriculum vitae for college faculty can be ambiguous and even misleading: they can obscure an individual's primary teaching and instructional achievements, tell less than they appear to, and convey an unintended message. Faculty should evaluate the clarity and force with which their vitae express their accomplishments and mirror their abilities.…

  8. Building a Vita for the Clinical Practice.

    ERIC Educational Resources Information Center

    Tentoni, Stuart C.

    Vita review is used by most prospective employers to determine which applicants will be interviewed for a particular position opening in clinical practice. Most graduate students have little knowledge and no training in this topic, which is vital for professional development. Specific examples of vitae construction are provided for one of the…

  9. Rutherford's curriculum vitae, 1894-1907.

    PubMed

    Cohen, M

    1995-06-01

    A single page, handwritten document was discovered when the Macdonald Physics building of McGill University in Montreal was gutted in 1978. This proved to be the draft of Ernest Rutherford's curriculum vitae (C.V.) covering the years 1894-1907, probably written in the autumn of 1906 when Rutherford was preparing to leave McGill. The C.V. contains 21 headings in chronological order, referring to research and other activities of Rutherford and his coauthors (especially Soddy and Barnes), plus a further set of headings relating to the associated investigations of Rutherford's team, including Eve and Hahn. A transcript of the document is provided, although in several places, Rutherford's handwriting is difficult to interpret, and the significance of his abbreviations is not always clear. Each of the items in the C.V. is discussed briefly in this review, in the light both of Rutherford's personal career and of the contribution of his team to the development and understanding of radioactivity. This contribution included the cause and nature of radioactivity (with Soddy), energy aspects of radioactive decay (with Barnes), elucidation of the uranium-radium, thorium and actinium series (Godlewski and Hahn), the radioactivity of the earth and atmosphere (Eve), the nature of the gamma rays (Eve) and, perhaps most important of all, the nature and properties of the alpha particle (Rutherford himself). The latter investigations led directly to Rutherford's later work in Manchester, including the nuclear model of the atom and artificial disintegration of the nucleus.

  10. Rutherford's curriculum vitae, 1894-1907.

    PubMed

    Cohen, M

    1995-06-01

    A single page, handwritten document was discovered when the Macdonald Physics building of McGill University in Montreal was gutted in 1978. This proved to be the draft of Ernest Rutherford's curriculum vitae (C.V.) covering the years 1894-1907, probably written in the autumn of 1906 when Rutherford was preparing to leave McGill. The C.V. contains 21 headings in chronological order, referring to research and other activities of Rutherford and his coauthors (especially Soddy and Barnes), plus a further set of headings relating to the associated investigations of Rutherford's team, including Eve and Hahn. A transcript of the document is provided, although in several places, Rutherford's handwriting is difficult to interpret, and the significance of his abbreviations is not always clear. Each of the items in the C.V. is discussed briefly in this review, in the light both of Rutherford's personal career and of the contribution of his team to the development and understanding of radioactivity. This contribution included the cause and nature of radioactivity (with Soddy), energy aspects of radioactive decay (with Barnes), elucidation of the uranium-radium, thorium and actinium series (Godlewski and Hahn), the radioactivity of the earth and atmosphere (Eve), the nature of the gamma rays (Eve) and, perhaps most important of all, the nature and properties of the alpha particle (Rutherford himself). The latter investigations led directly to Rutherford's later work in Manchester, including the nuclear model of the atom and artificial disintegration of the nucleus. PMID:7565376

  11. Structural and redox behavior of OxyVita, a zero-linked polymeric hemoglobin: comparison with natural acellular polymeric hemoglobins.

    PubMed

    Harrington, John P; Orlik, Kseniya; Orlig, Kseniya; Zito, Samantha L; Wollocko, Jacek; Wollocko, Hanna

    2010-04-01

    A zero-linked polymeric hemoglobin (OxyVita Hb) has been developed for application as an acellular therapeutic hemoglobin-based-oxygen-carrier (HBOC). For effective and safe oxygen binding, transport and delivery, an HBOC must meet essential molecular requirements related to its structural integrity and redox stability. OxyVita is a super polymer possessing an average M.wt. of 17 x 10(6) Da. Structural integrity was determined by unfolding studies of OxyVita in the presence of increasing concentrations of urea. The unfolding midpoints (D(1/2)) of different preparations of OxyVita (solution and powder forms) were compared to Lumbricus Hb (LtHb) and Arenicola Hb (ArHb), natural acellular polymeric hemoglobins, which are serving as models for an effective and safe acellular HBOC. Reduction studies of OxyVita Hb using endogenous reducing agents were also investigated. Results from these studies indicate that: 1) OxyVita Hb exhibits greater resistance to conformational change than either LtHb or ArHb in the reduced (oxyHb) state; and 2) the reduction of met OxyVita Hb to oxyHb occurs slowly in the presence of either ascorbic acid (70% reduction in 560 min.) or beta-NADH (40% reduction in 90 min.). These studies provide consistent evidence that OxyVita Hb possesses physiochemical properties that exhibit structural integrity and redox behavior necessary for functioning as an effective and safe HBOC within clinical applications. These results are in agreement with observations made by other investigators as to the reduction in heme-loss of OxyVita Hb, essential for the reversible binding/release of molecular oxygen within the circulatory system. PMID:20196683

  12. Structural and redox behavior of OxyVita, a zero-linked polymeric hemoglobin: comparison with natural acellular polymeric hemoglobins.

    PubMed

    Harrington, John P; Orlik, Kseniya; Orlig, Kseniya; Zito, Samantha L; Wollocko, Jacek; Wollocko, Hanna

    2010-04-01

    A zero-linked polymeric hemoglobin (OxyVita Hb) has been developed for application as an acellular therapeutic hemoglobin-based-oxygen-carrier (HBOC). For effective and safe oxygen binding, transport and delivery, an HBOC must meet essential molecular requirements related to its structural integrity and redox stability. OxyVita is a super polymer possessing an average M.wt. of 17 x 10(6) Da. Structural integrity was determined by unfolding studies of OxyVita in the presence of increasing concentrations of urea. The unfolding midpoints (D(1/2)) of different preparations of OxyVita (solution and powder forms) were compared to Lumbricus Hb (LtHb) and Arenicola Hb (ArHb), natural acellular polymeric hemoglobins, which are serving as models for an effective and safe acellular HBOC. Reduction studies of OxyVita Hb using endogenous reducing agents were also investigated. Results from these studies indicate that: 1) OxyVita Hb exhibits greater resistance to conformational change than either LtHb or ArHb in the reduced (oxyHb) state; and 2) the reduction of met OxyVita Hb to oxyHb occurs slowly in the presence of either ascorbic acid (70% reduction in 560 min.) or beta-NADH (40% reduction in 90 min.). These studies provide consistent evidence that OxyVita Hb possesses physiochemical properties that exhibit structural integrity and redox behavior necessary for functioning as an effective and safe HBOC within clinical applications. These results are in agreement with observations made by other investigators as to the reduction in heme-loss of OxyVita Hb, essential for the reversible binding/release of molecular oxygen within the circulatory system.

  13. A Day in the Life at DaVita Academy

    ERIC Educational Resources Information Center

    Weinstein, Margery

    2010-01-01

    When a company name means "giving life," the bar for learning and development programs is held high. In this article, the author describes what it takes to graduate from DaVita Academy, the soft skills training program dialysis services company DaVita offers all its employees. DaVita's chief executive officer, Kent Thiry, states that the Academy…

  14. How to compile a curriculum vitae.

    PubMed

    Fish, J

    The previous article in this series tackled the best way to apply for a job. Increasingly, employers request a curriculum vitae as part of the application process. This article aims to assist you in compiling a c.v. by discussing its essential components and content.

  15. 7 CFR 3402.15 - Faculty vitae.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Faculty vitae. 3402.15 Section 3402.15 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE FOOD AND AGRICULTURAL SCIENCES NATIONAL NEEDS GRADUATE AND POSTGRADUATE FELLOWSHIP GRANTS PROGRAM Preparation of an Application § 3402.15 Faculty...

  16. 7 CFR 3402.15 - Faculty vitae.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Faculty vitae. 3402.15 Section 3402.15 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE FOOD AND AGRICULTURAL SCIENCES NATIONAL NEEDS GRADUATE AND POSTGRADUATE FELLOWSHIP GRANTS PROGRAM Preparation of an Application § 3402.15 Faculty...

  17. PHP-HT (VitaResc Biotech).

    PubMed

    Baldwin, A; Wiley, E

    2001-04-01

    VitaResc (formerly Apex) is developing PHP-HT, pyridoxalated hemoglobin polyoxyethylene conjugate, for the potential treatment of nitric oxide-induced shock (characterized by hypotension), associated with various etiologies, initially in septic shock. A phase I safety study and an initial phase I/II patient trial for NO-induced shock have been completed, and VitaResc has enrolled patients in three of five planned cohorts in a continuation of these trials to include a protocol of continuous infusion and dose escalation [330680,349187,390918]. The results from the dose escalation trials are expected to provide the basis for a randomized, controlled phase II/III pivotal trial of PHP-HT [390918]. VitaResc has licensed PHP-HT exclusively from Ajinomoto for all indications, worldwide, except Japan [275263]. Ajinomoto originally developed the human derived and chemically modified hemoglobin preparation as a blood substitute, but no development has been reported by the company since 1997 [275277,303577]. The other potential indications of PHP-HT include shock associated with burns, pancreatitis, hemodialysis and cytokine therapies [275277]. VitaResc expects the annual market potential of PHP-HT to exceed 1 billion dollars [330680].

  18. 7 CFR 3402.15 - Faculty vitae.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Faculty vitae. 3402.15 Section 3402.15 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE FOOD AND AGRICULTURAL SCIENCES NATIONAL NEEDS GRADUATE AND POSTGRADUATE FELLOWSHIP GRANTS PROGRAM Preparation of an Application § 3402.15 Faculty...

  19. 7 CFR 3402.15 - Faculty vitae.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Faculty vitae. 3402.15 Section 3402.15 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE FOOD AND AGRICULTURAL SCIENCES NATIONAL NEEDS GRADUATE AND...

  20. The curriculum vitae sending the right message.

    PubMed

    Shellenbarger, Teresa; Chunta, Kristy S

    2007-01-01

    When reviewing curriculum vitae (CV), it becomes clear that some CV information provides a better reflection of work completed than others do. The authors provide a description of common CV errors, propose strategies to avoid such problems, and suggest methods for developing an accurate and clear CV that highlights accomplishments and clearly represents the work. Tips for updating CV and suggestions for electronic formats are also provided.

  1. A resume or curriculum vitae for success.

    PubMed

    Markey, B T; Campbell, R L

    1996-01-01

    Nurses who are searching for new positions can enhance their job employment potential with well-written resumes. Scholarship and award recognition also can be improved by creating well-written resumes and/or curricula vitae. Appropriate cover letters effectively introduce nurses to employers or review committees. This article presents a few basic suggestions that can simplify the creation of any of these documents and help nurses produce a quality product.

  2. Creating Curriculum Vitae for Understanding People on the Web

    NASA Astrophysics Data System (ADS)

    Ueda, Hiroshi; Murakami, Harumi; Tatsumi, Shoji

    When users find information about people from the results of Web people searches, they often need to browse many obtained Web pages and check much unnecessary information. This task is time-consuming and complicates the understanding of the designated people. We investigate a method that integrates the useful information obtained from Web pages and displays them to understand people. We focus on curriculum vitae, which are widely used for understanding people. We propose a method that extracts event sentences from Web pages and displays them like a curriculum vita. The event sentence includes both time and events related to a person. Our method is based on the following: (1) extracting event sentences using heuristics and filtering them, (2) judging whether event sentences are related to a designated person by mainly using the patterns of HTML tags, (3) classifying these sentences to categories by SVM, and (4) clustering event sentences including both identical times and events. Experimental results revealed the usefulness of our proposed method.

  3. 75 FR 22437 - Community Volunteer Income Tax Assistance (VITA) Matching Grant Program-Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... Internal Revenue Service Community Volunteer Income Tax Assistance (VITA) Matching Grant Program... Volunteer Income Tax Assistance (VITA) Matching Grant Program. DATES: Application packages are available... Income Tax Assistance (VITA) Matching Grant Demonstration Program for tax return preparation is...

  4. 76 FR 30243 - Community Volunteer Income Tax Assistance (VITA) Matching Grant Program-Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... Internal Revenue Service Community Volunteer Income Tax Assistance (VITA) Matching Grant Program... Volunteer Income Tax Assistance (VITA) Matching Grant Program. DATES: Application packages are available... . SUPPLEMENTARY INFORMATION: Authority for the Community Volunteer Income Tax Assistance (VITA) Matching...

  5. How to present a curriculum vitae.

    PubMed

    Ellis, J

    1985-10-01

    At times, as for example when candlelight flickers on bottle and glasses, it is not unpleasant to look into a pair of warm and friendly eyes and respond to the words "Tell me about yourself." Completing a curriculum vitae (CV), however, is a less attractive proposition, especially when applying for an appointment. Even those who are fond of talking about themselves can find it difficult. Some find it embarrassing. Some, judging from the poorly presented data which frequently accompany applications even for senior posts, are unaware of the important part the CV plays in the selection process.

  6. [Curriculum vitae organization: the Lattes software platform].

    PubMed

    Amorin, Cristiane V

    2003-05-01

    Curriculum vitae is a Latin expression meaning "career" or "life course". That means the data set concerning name, age, marital status, situation, studies, diplomas, published works and other activities of a student, an applicant for a position, for an exam or for a public office, and others. In short, it is the document that provides an outlook of the person as an individual; that is why this document must be carefully prepared as to precise and true contents, as to presentation and as to writing.

  7. Humanae Vitae and education for chastity.

    PubMed

    Lopez Trujillo, A

    1994-01-01

    In order to teach children to live chaste lives, their parents must also be living in accordance with the tenets expressed in the Pope's "Humanae Vitae." Periodic continence from sexual intercourse affords tranquility and peace to married life and allows parents to have a deeper influence on the education of their children. Living according to the encyclical promotes a reverence for life; it enhances communication in the family and allows children to witness a stable marriage. In addition to supporting the vocation to a stable marriage, the encyclical also promotes the ability of the family to nourish religious vocations in the children. The encyclical also reiterates the rights of parents to provide sex education to their children at home instead of surrendering this right to other institutions. Sex education (or, preferably, education for chastity) must be positive (and not reduce everything to biology), prudent and clear (holding moral values), and delicate (rather than explicit). By mid- to late-adolescence, young people should know that natural ways of spacing children are available, but they do not need to have the extensive counseling afforded to engaged couples. "Humanae Vitae" presents a bridge across the generations in family life which provides hope for the future.

  8. A professional curriculum vitae will open career doors.

    PubMed

    Harper, D S

    1999-01-01

    In today's challenging healthcare environment, it is essential for nurse practitioners to be able to describe themselves professionally on paper to compete for practice and academic opportunities. Nurse practitioners are competing with physician assistants as well as physicians for primary and acute care positions. A carefully compiled curriculum vitae will present the individual in the best light possible to help open career doors and enhance chances of success. Preparing a curriculum vitae will serve to highlight relevant professional accomplishments, whatever the setting, toward the fulfillment of professional goals. This article reviews the current professional print and electronic literature on preparing a curriculum vitae to assist the nurse practitioner in developing this vital document.

  9. Impact resistance of oil-immersed lignum vitae.

    PubMed

    Yin, Wei; Shan, Lei; Lu, Hongyu; Zheng, Yelong; Han, Zhiwu; Tian, Yu

    2016-07-18

    Biological materials immersed in vegetable and mineral oil, such as rattan armor and wooden sleepers, have been extensively used since ancient times because of their excellent mechanical properties. This study quantitatively investigated the viscoelasticity and tribological performance of lignum vitae immersed in poly-alpha-olefin (PAO) and tung oils (Aleuritesfordii Hemsl.) to reveal the mechanism of impact resistance. The acceleration of samples immersed in tung oil was higher than that of dry and PAO-immersed samples in the first impact. The elastic modulus of the samples immersed in tung oil increased slightly. The impact damage on the samples immersed in tung oil was reduced because of the low friction coefficient (0.07) resulted in a low wear rate. The extent of impact damage on the samples immersed in tung oil was approximately 34% and 58% lower than that on the dry and PAO oil-immersed samples, respectively, under an angle of 20° and a height of 10 cm. The impact damage on the PAO-immersed samples was reduced because of low friction coefficient. However, impact damage increased because of large elastic modulus. The findings of this study can serve as a reference for the application of modified biological materials with high strength and wear resistance.

  10. Impact resistance of oil-immersed lignum vitae

    PubMed Central

    Yin, Wei; Shan, Lei; Lu, Hongyu; Zheng, Yelong; Han, Zhiwu; Tian, Yu

    2016-01-01

    Biological materials immersed in vegetable and mineral oil, such as rattan armor and wooden sleepers, have been extensively used since ancient times because of their excellent mechanical properties. This study quantitatively investigated the viscoelasticity and tribological performance of lignum vitae immersed in poly-alpha-olefin (PAO) and tung oils (Aleuritesfordii Hemsl.) to reveal the mechanism of impact resistance. The acceleration of samples immersed in tung oil was higher than that of dry and PAO-immersed samples in the first impact. The elastic modulus of the samples immersed in tung oil increased slightly. The impact damage on the samples immersed in tung oil was reduced because of the low friction coefficient (0.07) resulted in a low wear rate. The extent of impact damage on the samples immersed in tung oil was approximately 34% and 58% lower than that on the dry and PAO oil-immersed samples, respectively, under an angle of 20° and a height of 10 cm. The impact damage on the PAO-immersed samples was reduced because of low friction coefficient. However, impact damage increased because of large elastic modulus. The findings of this study can serve as a reference for the application of modified biological materials with high strength and wear resistance. PMID:27425829

  11. Impact resistance of oil-immersed lignum vitae.

    PubMed

    Yin, Wei; Shan, Lei; Lu, Hongyu; Zheng, Yelong; Han, Zhiwu; Tian, Yu

    2016-01-01

    Biological materials immersed in vegetable and mineral oil, such as rattan armor and wooden sleepers, have been extensively used since ancient times because of their excellent mechanical properties. This study quantitatively investigated the viscoelasticity and tribological performance of lignum vitae immersed in poly-alpha-olefin (PAO) and tung oils (Aleuritesfordii Hemsl.) to reveal the mechanism of impact resistance. The acceleration of samples immersed in tung oil was higher than that of dry and PAO-immersed samples in the first impact. The elastic modulus of the samples immersed in tung oil increased slightly. The impact damage on the samples immersed in tung oil was reduced because of the low friction coefficient (0.07) resulted in a low wear rate. The extent of impact damage on the samples immersed in tung oil was approximately 34% and 58% lower than that on the dry and PAO oil-immersed samples, respectively, under an angle of 20° and a height of 10 cm. The impact damage on the PAO-immersed samples was reduced because of low friction coefficient. However, impact damage increased because of large elastic modulus. The findings of this study can serve as a reference for the application of modified biological materials with high strength and wear resistance. PMID:27425829

  12. 77 FR 20694 - Community Volunteer Income Tax Assistance (VITA) Matching Grant Program-Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-05

    ... Internal Revenue Service Community Volunteer Income Tax Assistance (VITA) Matching Grant Program... Volunteer Income Tax Assistance (VITA) Matching Grant Program. DATES: Application packages are available....Office@irs.gov . SUPPLEMENTARY INFORMATION: Authority for the Community Volunteer Income Tax...

  13. 78 FR 17776 - Community Volunteer Income Tax Assistance (VITA) Matching Grant Program-Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... Internal Revenue Service Community Volunteer Income Tax Assistance (VITA) Matching Grant Program... Volunteer Income Tax ] Assistance (VITA) Matching Grant Program. DATES: Application packages are available....Office@irs.gov . SUPPLEMENTARY INFORMATION: Authority for the Community Volunteer Income Tax...

  14. 75 FR 25314 - Community Volunteer Income Tax Assistance (VITA) Matching Grant Program-Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... Internal Revenue Service Community Volunteer Income Tax Assistance (VITA) Matching Grant Program... Income Tax Assistance (VITA) Matching Grant Program, which was published in the Federal Register on... packages for the 2011 Community Volunteer Income Tax Assistance (VITA) Matching Grant Program. FOR...

  15. Writing a curriculum vitae, resume or data sheet.

    PubMed

    Saltman, D

    1995-02-01

    This paper outlines a method for the preparation of a curriculum vitae, resume or data sheet, which is an essential document for professional people seeking employment or promotion. However, it needs to be accurate and relevant to the circumstances of the position, and requires regular updating.

  16. Curriculum vitae: An important tool for the nurse practitioner.

    PubMed

    Hicks, Rodney W; Roberts, Mary Ellen E

    2016-07-01

    Advanced practice nurses (APNs) should maintain a curriculum vitae (CV) that comprehensively reflects the individual's work and professional accomplishments. This article guides APNs through best practices for development of a CV. Tips are offered to help guide the content, format, and maintenance of the CV.

  17. VITA Experiential, Service-Learning, Learned Competencies, and Changed Mindsets

    ERIC Educational Resources Information Center

    Boneck, Robin; Barnes, Jeffrey N.; Stillman, Tyler F.

    2014-01-01

    The authors describe how Southern Utah University has integrated the U.S. Internal Revenue Service (IRS) Voluntary Income Tax Assistance (VITA) program as an experiential servicelearning activity for over a decade and a half. First, we describe the value of experiential servicelearning. Second, we detail the program, its oversight, its student…

  18. Accuracy of shade matching performed by colour blind and normal dental students using 3D Master and Vita Lumin shade guides.

    PubMed

    Vafaee, F; Rakhshan, V; Vafaei, M; Khoshhal, M

    2012-03-01

    The purpose of this study was to investigate whether 3D Master or VitaLumin shade guides could improve colour selection in individuals with normal and defective colour vision. First, colour perception of 260 dental students was evaluated. Afterwards, 9 colour blind and 9 matched normal subjects tried to detect colours of 10 randomly selected tabs from each kit and the correct/false answers were counted. Of the colour-defective subjects, 47.8% and 33.3% correctly detected the shade using 3D Master and VitaLumin, respectively. These statistics were 62.2% and 42.2% in normal subjects. In normal participants, but not in colour blind ones, 3D Master significantly improved shade matching accuracy compared to VitaLumin.

  19. A model curriculum vitae: what are the trainers looking for?

    PubMed

    Chambler, A F; Chapman-Sheath, P J; Pearse, M F

    1998-04-01

    In this new era of Calman, the curriculum vitae (CV) still remains the most important document in furthering the careers of doctors. A survey of postgraduate deans and college regional training advisors opinions on CVs was undertaken. The results have allowed a model CV to be compiled expressing the layout and most of the features which senior trainers feel are important when producing a CV.

  20. A curriculum vitae that gives you a competitive edge.

    PubMed

    Hinck, S M

    1997-07-01

    All nurses with advancing careers should maintain a current curriculum vitae (CV) to chronicle professional accomplishments. Whatever the work setting, a CV can showcase skills and achievements. It is used when applying for a new position, but also within one's current situation to inform other professionals of specific interests and abilities. This article reviews nursing literature regarding preparation of a CV and suggests a format for the advanced practice nurse to use when writing a CV.

  1. Application of VitaVallis dressing for infected wounds

    SciTech Connect

    Kirilova, N. V. Fomenko, A. N. Korovin, M. S.

    2015-11-17

    Today there is a growing demand for safe and efficient antimicrobial dressings for infected wound treatment. The antimicrobial sorption material for VitaVallis dressings was produced by one-stage oxidation of aluminum nanopowder in water in the presence of fibrous acetylcellulose matrix. Scanning electron microscopy revealed that the material is made up of fibers of diameter 1.5–3.0 µm with adhered agglomerated alumina nanosheets. An antimicrobial study revealed a high inhibitory effect of VitaVallis against the growth of gram-negative (E.coli, P. aeruginosa) and gram-positive (S. aureus) strains. The antimicrobial activity of the dressing against microbial pathogens on the wound surface was demonstrated in in vivo experiments on male rats. The dressing was also tested on volunteer patients. The testing showed reduction of the wound healing period, accelerated cleaning of the infected wound and enhanced tissue regeneration in the wound. The results demonstrate that the VitaVallis dressing can be used for the treatment of deep infected wounds.

  2. Application of VitaVallis dressing for infected wounds

    NASA Astrophysics Data System (ADS)

    Kirilova, N. V.; Fomenko, A. N.; Korovin, M. S.

    2015-11-01

    Today there is a growing demand for safe and efficient antimicrobial dressings for infected wound treatment. The antimicrobial sorption material for VitaVallis dressings was produced by one-stage oxidation of aluminum nanopowder in water in the presence of fibrous acetylcellulose matrix. Scanning electron microscopy revealed that the material is made up of fibers of diameter 1.5-3.0 µm with adhered agglomerated alumina nanosheets. An antimicrobial study revealed a high inhibitory effect of VitaVallis against the growth of gram-negative (E.coli, P. aeruginosa) and gram-positive (S. aureus) strains. The antimicrobial activity of the dressing against microbial pathogens on the wound surface was demonstrated in in vivo experiments on male rats. The dressing was also tested on volunteer patients. The testing showed reduction of the wound healing period, accelerated cleaning of the infected wound and enhanced tissue regeneration in the wound. The results demonstrate that the VitaVallis dressing can be used for the treatment of deep infected wounds.

  3. Conditional sampling schemes based on the Variable Interval Time Averaging (VITA) algorithm

    NASA Astrophysics Data System (ADS)

    Morrison, J. F.; Tsai, H. M.; Bradshaw, P.

    1986-08-01

    The variable interval time averaging (VITA) algorithm was tested in a variety of boundary layers for its ability to detect motions principally involved in the production of shear stress. A VITA+LEVEL scheme (which uses a variance and level criterion) was devised and is shown to produce length scale statistics that are independent of the conditioning criteria, where those from the VITA scheme are not.

  4. A balancing act: the curriculum vitae and the interview process.

    PubMed

    Lloyd, B A; Dickson, C J

    1994-01-01

    The authors believe that one possible solution to the dearth of minority nursing faculty in higher education is thorough preparation for the search process by the minority applicant. This article discusses the appointment/hiring process and provides the reader with authoritative and experiential information necessary for constructing a curriculum vitae (CV) and preparing for an interview. Armed with a proper CV and knowledge of potential interview questions, the authors believe that minority applicants will be able to maneuver their way through the maize of job interviews. In addition, suggestions are offered to those serving on promotion and tenure committees and administrators.

  5. The Curriculum Vitae--What It Is and What It Is Not.

    ERIC Educational Resources Information Center

    Newcomb, B. Joan; Murphy, Patricia A.

    1979-01-01

    Presents guidelines to nurses for preparing curriculum vitae, narrower and more stylized than resumes, which outline qualifications for academic positions, committees, and honors. Lists categories and describes content of information to be included on a vita (a sample is shown) and notes what to avoid. (MF)

  6. [Anesthesiological systems "Polinarkon-Vita" with microprocessor for artificial lung ventilation apparatuses and monitoring].

    PubMed

    Trushin, A I; Uliakov, G I; Reĭderman, E N

    2005-01-01

    The anesthesiological systems Polinarkon-Vita for adults and children are described. These systems were developed at VNIIMP-VITA, Ltd. on the basis of basic model of the anesthesiological system Polinarkon-E-Vita. The following new important units of the fifth generation apparatuses for inhalation anesthesia (IA) are described: Anestezist-4 monocomponent evaporator for liquid anesthetics (enfluran and isofluran); Diana, Diana-Det, and Elan-NR apparatuses for mechanical lung ventilation (MLV); dosimeters of medical gases, etc. These systems implement monitoring of vitally important functions of patient and parameters of IN and MLV. The anesthesiological systems Polinarkon-Vita are recommended for medical practice and commercially available from VNIIMP-VITA, Ltd. as small lots.

  7. The impact of 25 years of "Humanae Vitae".

    PubMed

    1993-08-01

    In 1968, Pope Paul VI reinforced the Catholic Church's position forbidding contraception in an encyclical known as "Humanae Vitae." The current Pope, John Paul II, has reiterated this position and stated that use of condoms is forbidden, even to prevent HIV transmission. Several public figures, including the IPPF President and the British Overseas Development Minister, have sought to initiate a dialogue with the Pope to express concern about population growth in developing countries. The Catholic Church is currently opposing efforts on the part of the Presidents of Peru and the Philippines to expand access to family planning (FP) programs. Many of the 500,000 women who die each year of pregnancy complications would have used contraceptives and lived, and an estimated 300 million developing world couples have no access to modern contraception, yet desire no more children. Many Catholics disagree with the Church's stance; 87% of US Catholics surveyed in 1992 stated that FP is the couple's choice. After 25 years of "Humanae Vitae," it is time for the Church to enter into dialogue and join efforts to improve life on earth in the next century. PMID:12345157

  8. 21 CFR 312.53 - Selecting investigators and monitors.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... assisting the investigator in the conduct of the investigation(s). (2) Curriculum vitae. A curriculum vitae... investigational purposes and will ensure that the requirements relating to obtaining informed consent (21 CFR part 50) and institutional review board review and approval (21 CFR part 56) are met; (e) Will report...

  9. The computerized medical record in gastroenterology: part 4. Health curriculum vitae.

    PubMed

    Jeanty, C

    1978-12-01

    The health curriculum vitae consists mainly of a chronological sequence of diagnoses, which are the mainstays of the medical record. Each diagnosis is connected vertically in the health curriculum vitae with its aetiological factors and its medical or surgical treatments in a casual concatenation; and horizontally throughout the other three parts of the record with its relevant functional, morphological (descriptive) and numerical laboratory data in a diagnostic association. The health curriculum vitae uses the Systematized Nomenclature of Medicine (SNOMED), the International Nomenclature of the Diseases of the Gastrointestinal Tract (CIOMS) and the International Standard Classification of Occupations of the Internationl Labour Office.

  10. Preparing a successful, role-specific curriculum vitae.

    PubMed

    Price, Bob

    2014-10-01

    An internet search reveals just how many articles there are on preparing a curriculum vitae (CV). The preparation of a CV should not be regarded as a 'one-off' event, to be updated periodically. A successful CV requires thoughtful preparation to ensure it is directed towards a specific post and should consider two important perspectives. First, an understanding of what is required of the practitioner in the nursing post (demand), and second, what the nurse can offer in terms of his or her skills, experience, qualities and qualifications (supply). The demands of the post will also include meeting professional standards, such as those that have emerged following consideration of the Report of the Mid Staffordshire NHS Foundation Trust Public Inquiry (Francis 2013). This article explores how to prepare a successful CV for a specific role, using a demand and supply perspective--where a nurse seeks to match the specific requirements of the post by summarising what he or she has to offer.

  11. Preparing a successful, role-specific curriculum vitae.

    PubMed

    Price, Bob

    2014-10-01

    An internet search reveals just how many articles there are on preparing a curriculum vitae (CV). The preparation of a CV should not be regarded as a 'one-off' event, to be updated periodically. A successful CV requires thoughtful preparation to ensure it is directed towards a specific post and should consider two important perspectives. First, an understanding of what is required of the practitioner in the nursing post (demand), and second, what the nurse can offer in terms of his or her skills, experience, qualities and qualifications (supply). The demands of the post will also include meeting professional standards, such as those that have emerged following consideration of the Report of the Mid Staffordshire NHS Foundation Trust Public Inquiry (Francis 2013). This article explores how to prepare a successful CV for a specific role, using a demand and supply perspective--where a nurse seeks to match the specific requirements of the post by summarising what he or she has to offer. PMID:25270484

  12. Antimicrobial Potential and Chemical Characterization of Serbian Liverwort (Porella arboris-vitae): SEM and TEM Observations.

    PubMed

    Kumar Tyagi, Amit; Bukvicki, Danka; Gottardi, Davide; Veljic, Milan; Guerzoni, Maria Elisabetta; Malik, Anushree; Marin, Petar D

    2013-01-01

    The chemical composition of Porella arboris-vitae extracts was determined by solid phase microextraction, gas chromatography-mass spectrometry (SPME GC-MS), and 66 constituents were identified. The dominant compounds in methanol extract of P. arboris-vitae were β-caryophyllene (14.7%), α-gurjunene (10.9%), α-selinene (10.8%), β-elemene (5.6%), γ-muurolene (4.6%), and allo-aromadendrene (4.3%) and in ethanol extract, β-caryophyllene (11.8%), α-selinene (9.6%), α-gurjunene (9.4%), isopentyl alcohol (8.8%), 2-hexanol (3.7%), β-elemene (3.7%), allo-aromadendrene (3.7%), and γ-muurolene (3.3%) were the major components. In ethyl acetate extract of P. arboris-vitae, undecane (11.3%), β-caryophyllene (8.4%), dodecane (6.4%), α-gurjunene (6%), 2-methyldecane (5.1%), hemimellitene (4.9%), and D-limonene (3.9%) were major components. The antimicrobial activity of different P. arboris-vitae extracts was evaluated against selected food spoilage microorganisms using microbroth dilution method. The Minimal Inhibitory Concentration (MIC) varied from 0.5 to 1.5 mg/mL and 1.25 to 2 mg/mL for yeast and bacterial strains, respectively. Significant morphological and ultrastructural alterations due to the effect of methanolic and ethanolic P. arboris-vitae extracts on S. Enteritidis have also been observed by scanning electron microscope and transmission electron microscope, respectively. The results provide the evidence of antimicrobial potential of P. arboris-vitae extracts and suggest its potential as natural antimicrobial agents for food preservation. PMID:23365607

  13. Antimicrobial Potential and Chemical Characterization of Serbian Liverwort (Porella arboris-vitae): SEM and TEM Observations

    PubMed Central

    Kumar Tyagi, Amit; Bukvicki, Danka; Gottardi, Davide; Veljic, Milan; Guerzoni, Maria Elisabetta; Malik, Anushree; Marin, Petar D.

    2013-01-01

    The chemical composition of Porella arboris-vitae extracts was determined by solid phase microextraction, gas chromatography-mass spectrometry (SPME GC-MS), and 66 constituents were identified. The dominant compounds in methanol extract of P. arboris-vitae were β-caryophyllene (14.7%), α-gurjunene (10.9%), α-selinene (10.8%), β-elemene (5.6%), γ-muurolene (4.6%), and allo-aromadendrene (4.3%) and in ethanol extract, β-caryophyllene (11.8%), α-selinene (9.6%), α-gurjunene (9.4%), isopentyl alcohol (8.8%), 2-hexanol (3.7%), β-elemene (3.7%), allo-aromadendrene (3.7%), and γ-muurolene (3.3%) were the major components. In ethyl acetate extract of P. arboris-vitae, undecane (11.3%), β-caryophyllene (8.4%), dodecane (6.4%), α-gurjunene (6%), 2-methyldecane (5.1%), hemimellitene (4.9%), and D-limonene (3.9%) were major components. The antimicrobial activity of different P. arboris-vitae extracts was evaluated against selected food spoilage microorganisms using microbroth dilution method. The Minimal Inhibitory Concentration (MIC) varied from 0.5 to 1.5 mg/mL and 1.25 to 2 mg/mL for yeast and bacterial strains, respectively. Significant morphological and ultrastructural alterations due to the effect of methanolic and ethanolic P. arboris-vitae extracts on S. Enteritidis have also been observed by scanning electron microscope and transmission electron microscope, respectively. The results provide the evidence of antimicrobial potential of P. arboris-vitae extracts and suggest its potential as natural antimicrobial agents for food preservation. PMID:23365607

  14. A New Work Sample Battery for Vocational Assessment of the Disadvantaged: VITAS.

    ERIC Educational Resources Information Center

    Abrams, Michael

    1979-01-01

    Describes the development of a work sample battery designed for assessment of vocational aptitudes, interests, and temperament in a disadvantaged client population. VITAS provides information about factors most related to success on the job: interest in the job, temperament for the job, and aptitudes for physical and cognitive components of the…

  15. The Vita Activa as Compass: Navigating Uncertainty in Teaching with Hannah Arendt

    ERIC Educational Resources Information Center

    Rogers, Carrie Ann Barnes

    2010-01-01

    This dissertation is an exploration of stories of uncertainty in the lives of elementary teachers and the value that the ideas of Hannah Arendt lend to the discussion around uncertainty. In "The Human Condition" (1958) Hannah Arendt theorizes the life of action, the "vita activa". Arendtian action is inherently uncertain because to be "capable of…

  16. Using the Curriculum Vita To Study the Career Paths of Scientists and Engineers: An Assessment.

    ERIC Educational Resources Information Center

    Lane, Eliesh O'Neil; Dietz, James S.; Chompalov, Ivan; Bozeman, Barry; Park, Jongwon

    The usefulness of the curriculum vita (CV) as a data source for examining the career paths of scientists and engineers was studied. CVs were obtained in response to an e-mail message sent to researchers working in the area of biotechnology who were funded by the National Science Foundation (55 responses) or listed as authors (industry only) in the…

  17. Conditional-sampling schemes for turbulent flow, based on the variable-interval time averaging (VITA) algorithm

    NASA Astrophysics Data System (ADS)

    Morrison, J. F.; Tsai, H. M.; Bradshaw, P.

    The variable-interval time-averaging ('VITA') algorithm has been tested in a variety of turbulent boundary layers for its ability to detect shear-stress-producing motions from hot-wire signals. A 'VITA+LEVEL' scheme (which uses criteria for both short-time variance and short-time average, i.e., 'level') has been devised, and used in several different boundary layers. This scheme yields length-scale statistics that are acceptably independent of the conditioning criteria, which the VITA scheme does not.

  18. Importance of components of the curriculum vitae in determining appointment to senior registrar posts.

    PubMed

    Conn, D A; Asbury, A J

    1994-07-01

    To evaluate the opinions of regional education advisers, academics and other consultants about features of the curriculum vitae, we undertook a small attitude survey. The response rate was 73%, which provided data from a total of 78 influential anaesthetists. The respondents' attitude to each feature of the curriculum vitae was reported using a linear visual analogue scale. The three groups had similar attitude scores to most features, but not to research time, training time, higher degrees and abstracts of papers presented to the Anaesthetic Research Society. Publications in the main anaesthesia journals, time in other major medical specialties, research and the possession of a higher degree were scored highly by all respondents. Papers in non-peer-reviewed journals, letters, unsubmitted papers, and time in training for general practice attracted lower scores. The free text comments of many respondents indicated a considerable disillusionment about the whole appointments process.

  19. Historical and biochemical aspects of a seventeenth century gold-based aurum vitae recipe.

    PubMed

    Rubbiani, Riccardo; Wahrig, Bettina; Ott, Ingo

    2014-08-01

    The medicinal chemistry and biomedical applications of gold complexes have been intensively studied over the last decades. Some complexes have been used for the treatment of rheumatoid arthritis, and a considerable number of new metallodrug candidates have been developed as new anticancer drugs and anti-infectives. However, the therapeutic use of gold and its complexes goes back to ancient times and was also of great importance for alchemists until the modern age. In this report, we give an overview of the alchemic medicine between the sixteenth and the early eighteenth century and describe the cytotoxicity and thioredoxin reductase (TrxR) inhibition of a typical "aurum vitae" medicine, which was prepared according to a recipe by Bartholomäus Kretschmar from the seventeenth century. "Aurum vitae" consists of a mixture of gold, mercury and antimony complexes and shows the expected cytotoxic and TrxR inhibitory properties providing some rationale for therapeutic effects of this kind of historical medicinal preparation.

  20. Effective Design and Evaluation of Serious Games: The Case of the e-VITA Project

    NASA Astrophysics Data System (ADS)

    Pappa, Dimitra; Pannese, Lucia

    Learning and training are presently facing new challenges and a strong transformation. The use of electronic games for education (game-based learning) promotes an agile, immersive and stimulating form of learning that fosters learner engagement and motivation. Nonetheless, the design of effective and engaging educational games is a creative process that is unique to each situation. This paper discusses the inherent challenges of building intellectually appropriate and engaging games and presents the methodology adopted in the case of the e-VITA project that applies GBL to promote knowledge sharing and transfer for intergenerational learning. The paper analyses the e-VITAframework for SGs evaluation, which is central to the project's iterative development approach. Early findings stemming from the validation of the e-VITA prototype game are also presented.

  1. In Vivo Evaluations of Inter-Observer Reliability Using VITA Easyshade® Advance 4.0 Dental Shade-Matching Device

    PubMed Central

    KNEZOVIĆ, Dubravka; ZLATARIĆ, Davor; Illeš, Iva Ž.; Alajbeg, Maja; Žagar

    2016-01-01

    Objectives The aim of this study was to evaluate the inter-observer reliability of dental shade-matching device using an in vivo model. Materials and methods Four observers who were well trained in color assessment and handling of the dental shade-matching device determined teeth color and CIE-Lab values on maxillary right central incisors in 10 patients with completely healthy and intact dentitions. VITA Easyshade® Advance 4.0 shade-matching device was utilized to measure the central region of the labial surface of all investigated teeth, twice by each observer. The inter-observer reliability of the measurements was observed and deviations between Lab and ∆E values between the observers were calculated. Intraclass correlation coefficients (ICCs) were used to analyze inter-observer reliability. Results One-way ANOVA showed no statistically significant differences in color measurement of four observers in all the measured values (p>0.05). Delta E values ranged from 3.018 to 5.234. Although some small differences existed, statistically significant differences between the observers were not found (p>0.05). Inter-observer ICCs were very high for all observers (from 0.651 to 0.992). Conclusion Inter-examiner reliability of measurements using VITA Easyshade® Advance 4.0 shade-matching device was acceptable. Apart from the digital equipment, a well trained observer seems to be crucial in order to achieve correct dental color measurement.

  2. In Vivo Evaluations of Inter-Observer Reliability Using VITA Easyshade® Advance 4.0 Dental Shade-Matching Device

    PubMed Central

    KNEZOVIĆ, Dubravka; ZLATARIĆ, Davor; Illeš, Iva Ž.; Alajbeg, Maja; Žagar

    2016-01-01

    Objectives The aim of this study was to evaluate the inter-observer reliability of dental shade-matching device using an in vivo model. Materials and methods Four observers who were well trained in color assessment and handling of the dental shade-matching device determined teeth color and CIE-Lab values on maxillary right central incisors in 10 patients with completely healthy and intact dentitions. VITA Easyshade® Advance 4.0 shade-matching device was utilized to measure the central region of the labial surface of all investigated teeth, twice by each observer. The inter-observer reliability of the measurements was observed and deviations between Lab and ∆E values between the observers were calculated. Intraclass correlation coefficients (ICCs) were used to analyze inter-observer reliability. Results One-way ANOVA showed no statistically significant differences in color measurement of four observers in all the measured values (p>0.05). Delta E values ranged from 3.018 to 5.234. Although some small differences existed, statistically significant differences between the observers were not found (p>0.05). Inter-observer ICCs were very high for all observers (from 0.651 to 0.992). Conclusion Inter-examiner reliability of measurements using VITA Easyshade® Advance 4.0 shade-matching device was acceptable. Apart from the digital equipment, a well trained observer seems to be crucial in order to achieve correct dental color measurement. PMID:27688424

  3. Conditional-sampling schemes for turbulent flow, based on the variable-interval time averaging (VITA) algorithm

    NASA Astrophysics Data System (ADS)

    Morrison, J. F.; Tsai, H. M.; Bradshaw, P.

    1988-12-01

    The variable-interval time-averaging (“VITA”) algorithm has been tested in a variety of turbulent boundary layers for its ability to detect shear-stress-producing motions from hot-wire signals. A “VITA + LEVEL” scheme (which uses criteria for both short-time variance and short-time average, i.e.“level”) has been devised, and used in several different boundary layers. This scheme yields length-scale statistics that are acceptably independent of the conditioning criteria, which the VITA scheme does not.

  4. Historical and biochemical aspects of a seventeenth century gold-based aurum vitae recipe.

    PubMed

    Rubbiani, Riccardo; Wahrig, Bettina; Ott, Ingo

    2014-08-01

    The medicinal chemistry and biomedical applications of gold complexes have been intensively studied over the last decades. Some complexes have been used for the treatment of rheumatoid arthritis, and a considerable number of new metallodrug candidates have been developed as new anticancer drugs and anti-infectives. However, the therapeutic use of gold and its complexes goes back to ancient times and was also of great importance for alchemists until the modern age. In this report, we give an overview of the alchemic medicine between the sixteenth and the early eighteenth century and describe the cytotoxicity and thioredoxin reductase (TrxR) inhibition of a typical "aurum vitae" medicine, which was prepared according to a recipe by Bartholomäus Kretschmar from the seventeenth century. "Aurum vitae" consists of a mixture of gold, mercury and antimony complexes and shows the expected cytotoxic and TrxR inhibitory properties providing some rationale for therapeutic effects of this kind of historical medicinal preparation. PMID:24748221

  5. The Professoriate in the Field of Educational Administration: Insights from an Analysis of Journal Authors' Curricula Vitae

    ERIC Educational Resources Information Center

    Oplatka, Izhar

    2010-01-01

    Purpose: Based on a qualitative content analysis of 57 curricula vitae of authors who published their work in the major journals of the educational administration (EA) field, this paper seeks to display the career of EA authors and to suggest some epistemological implications for the field. Design/methodology/approach: The analysis is based on…

  6. Out of their comfort zone. Dialysis provider DaVita needs to integrate big physician practice to move toward integrated care.

    PubMed

    Kutscher, Beth

    2013-09-16

    DaVita's acquisition of multispecialty group HealthCare Partners hasn't come without growing pains. But the deal has put the dialysis provider in a position to go beyond kidneys to serving the whole patient. The goal of the merger, says DaVita Co-chairman and CEO Kent Thiry, left, is to prepare for a time when DaVita is expected not only to provide dialysis, but also help keep nephrology patients out of the hospital and manage their other chronic conditions.

  7. Vita-Assay™ Method of Enrichment and Identification of Circulating Cancer Cells/Circulating Tumor Cells (CTCs).

    PubMed

    Tulley, Shaun; Zhao, Qiang; Dong, Huan; Pearl, Michael L; Chen, Wen-Tien

    2016-01-01

    The ability to capture, enrich, and propagate circulating cancer cells/circulating tumor cells (CTCs) for downstream analyses such as ex vivo drug-sensitivity testing of short-term cultures of CTCs, single cell sorting of CTCs by fluorescence activated cell sorting (FACS), animal injection tumor and/or metastasis formation studies, next generation sequencing (NGS), gene expression profiling, gene copy number determination, and epigenomic analyses is of high priority and of immense importance to both the basic research and translational/clinical research communities. Vitatex Inc.'s functional cell separation technology, constructed as Vita-Assay™ (AG6W, AN6W, AR6W) culture plates, is based on the preferential adhesion of invasive rare blood cells of tissue origin to a tissue or tumor microenvironment mimic-the so-called cell adhesion matrix (CAM), which has a demonstrated ability to enrich viable CTCs from blood up to one-million fold.The CAM-scaffold allows for the functional capture and identification of invasive CTCs (iCTCs) including invasive tumor progenitor (TP) cells from cancer-patients' blood. CAM-captured CTCs are capable of ingesting the CAM (CAM+) itself. Green and red fluorescent versions of Vita-Assay™ (AG6W and AR6W) allow for direct visualization of CAM-uptake by cancer cells. Vita-Assay™ CAM-enrichment has allowed for sensitive multiplex flow cytometric and microscopic detection of iCTCs from patients with cancers of the breast, ovary, prostate, pancreas, colorectum, and lung; it has also been successfully utilized for ex vivo drug-sensitivity testing of ovarian-cancer patient CTCs. The CAM enrichment method is equally suitable for the separation of iCTCs and TP cells in ascites and pleural fluid.

  8. Delivering Better Quality of Care: Relentless Focus and Starting with the End in Mind at DaVita.

    PubMed

    Nissenson, Allen R

    2016-01-01

    The care of patients with end-stage renal disease has been evolving since the implementation of the Medicare entitlement for ESRD in 1973. Over the past 43 years, patients with ESRD have become increasingly complex with multiple comorbid conditions and the average age of new ESRD patients has continued to climb. Despite these challenges, progress has been made in improving mortality and morbidity, but the pace has generally been slow. The consolidation of the US dialysis industry has afforded large providers to achieve economies of scale and efficiencies. By reinvesting resources in innovative programs, the improvements in outcomes have accelerated. At DaVita, we have reimagined care for our ESRD patients by creating a Patient-Focused Quality Pyramid, an approach to holistic, patient-centered care that builds on the foundation of well-known dialysis metrics like adequacy and anemia management to drive more complex programs like fluid, medication, diabetes, and infection management. The ultimate goal is to improve survival, keep patients healthy and out of the hospital, enhance the patient experience of care, and thereby achieve optimal health-related quality of life. For two consecutive years, DaVita facilities, using this approach, have achieved superior performance in the CMS 5-Star rating program, most recently with 46% of facilities achieving 4 or 5 stars compared with only 23% of facilities outside of DaVita receiving 4 or 5 stars. This rating system has components of fundamentals, and more complex outcomes and our results are an external validation of the success of our approach in improving the lives of patients. PMID:26749498

  9. Tips for a physician in getting the right job, part II: the curriculum vitae, cover letter, and personal statement.

    PubMed

    Harolds, Jay A

    2013-09-01

    It is very important that a job seeker prepares an excellent curriculum vitae (CV) and cover letter. Often a personal statement is also needed. If these are not done well, often an interview is not granted. There are different formats and headings for the CV, depending on the type of job sought and the institution the job is located in. There are also some differences in how this is done between different countries. However, there are also many common elements of a proper CV.

  10. Tips for a physician in getting the right job, part II: the curriculum vitae, cover letter, and personal statement.

    PubMed

    Harolds, Jay A

    2013-09-01

    It is very important that a job seeker prepares an excellent curriculum vitae (CV) and cover letter. Often a personal statement is also needed. If these are not done well, often an interview is not granted. There are different formats and headings for the CV, depending on the type of job sought and the institution the job is located in. There are also some differences in how this is done between different countries. However, there are also many common elements of a proper CV. PMID:23860367

  11. VITA-D: Cholecalciferol substitution in vitamin D deficient kidney transplant recipients: A randomized, placebo-controlled study to evaluate the post-transplant outcome

    PubMed Central

    Thiem, Ursula; Heinze, Georg; Segel, Rudolf; Perkmann, Thomas; Kainberger, Franz; Mühlbacher, Ferdinand; Hörl, Walter; Borchhardt, Kyra

    2009-01-01

    Background Vitamin D does not only regulate calcium homeostasis but also plays an important role as an immune modulator. It influences the immune system through the induction of immune shifts and regulatory cells resulting in immunologic tolerance. As such, vitamin D is thought to exert beneficial effects within the transplant setting, especially in kidney transplant recipients, considering the high prevalence of vitamin D deficiency in kidney transplant recipients. Methods/Design The VITA-D study, a randomized, placebo-controlled, double-blind study with two parallel groups including a total of 200 kidney transplant recipients, is designed to investigate the immunomodulatory and renoprotective effects of cholecalciferol (vitamin D3) within the transplant setting. Kidney transplant recipients found to have vitamin D deficiency defined as 25-hydroxyvitamin D3 < 50 nmol per liter will be randomly assigned to receive either oral cholecalciferol therapy or placebo and will be followed for one year. Cholecalciferol will be administered at a dose of 6800 International Units daily over a time period of one year. The objective is to evaluate the influence of vitamin D3 substitution in vitamin D deficient kidney transplant recipients on the post-transplant outcome. As a primary endpoint glomerular filtration rate calculated with the MDRD formula (modification of diet in renal disease) one year after kidney transplantation will be evaluated. Incidence of acute rejection episodes, and the number and severity of infections (analyzed by means of C-reactive protein) within the first year after transplantation will be monitored as well. As a secondary endpoint the influence of vitamin D3 on bone mineral density within the first year post-transplant will be assessed. Three DXA analyses will be performed, one within the first four weeks post-transplant, one five months and one twelve months after kidney transplantation. Trial Registration ClinicalTrials.gov NCT00752401 PMID

  12. Comparative assessment of the organization of the colors of the Vita Classical color pallet by digital images and visual analysis for dental bleaching

    NASA Astrophysics Data System (ADS)

    Oliveira-Júnior, O. B.; Cioffi, Mariana S.; Cesnik, R. M.; Florez, Fernando L. E.; Bagnato, Vanderlei S.; Corrêa-dos-Santos, Diego R.; Fornazari, Fabio P.

    2009-02-01

    New formularizations, techniques and devices have become the dental whitening most safe and with better results. Although this, the verification of the levels whitening is being continued for visual comparison, that is an empirical, subjective method, subject to errors and dependent of the individual interpretation. Normally the result of the whitening is express for the amplitude of displacement between the initial and the final color, being take like reference the tonalities of a scale of color commanded of darkest for more clearly. Although to be the most used scale , the ordinance of the Vita Classical ® - Vita, according to recommendations of the manufacturer, reveals inadequate for the evaluation of the whitening. From digital images and of algorithm OER (ordinance of the reference scale), especially developed for the ScanWhite ©, the ordinance of the tonalities of the scale Vita Classical® was made. For such, the values of the canals of color R, G, and B of medium part average of the crowns was adopted as reference for evaluation. The images had been taken with the camera Sony Cybershoot DSC F828. The results of the computational ordinance had been compared with the sequence proposal for the manufacturer and with the earned one for the visual evaluation, carried through by 10 volunteers, under standardized conditions of illumination. It statistics analyzes demonstrated significant differences between the ordinances.

  13. For an indeterministic ethics. The emptiness of the rule in dubio pro vita and life cessation decisions

    PubMed Central

    Pavlovic, Dragan; Lehmann, Christian; Wendt, Michael

    2009-01-01

    It is generally claimed that there exist exceptional circumstances when taking human life may be approved and when such actions may be justified on moral grounds. Precise guidelines in the medical field for making such decisions concerning patients who are terminally ill or have irreparable injuries incompatible with a bearable life, are difficult to establish. Recommendations that take the particular logical form of a rule, such as "in dubio pro vita", "when in doubt favour life") have been suggested and in some countries incorporated into legal texts (Germany). We claim here that such a rule is of no value since it is open-ended and always allows for doubt, and a decision to employ measures that would support human life could always be argued to be a valid choice. Preservation of this rule could be encouraged, but giving it the force of law may put physicians at risk, as they may be challenged for choosing to terminate life in otherwise ethically and medically uncontroversial circumstances. PMID:19442284

  14. Theoretical model for VITA-educed coherent structures in the wall region of a turbulent boundary layer

    NASA Technical Reports Server (NTRS)

    Landahl, Marten T.

    1988-01-01

    Experiments on wall-bounded shear flows (channel flows and boundary layers) have indicated that the turbulence in the region close to the wall exhibits a characteristic intermittently formed pattern of coherent structures. For a quantitative study of coherent structures it is necessary to make use of conditional sampling. One particularly successful sampling technique is the Variable Integration Time Averaging technique (VITA) first explored by Blackwelder and Kaplan (1976). In this, an event is assumed to occur when the short time variance exceeds a certain threshold multiple of the mean square signal. The analysis presented removes some assumptions in the earlier models in that the effects of pressure and viscosity are taken into account in an approximation based on the assumption that the near-wall structures are highly elongated in the streamwise direction. The appropriateness of this is suggested by the observations but is also self consistent with the results of the model which show that the streamwise dimension of the structure grows with time, so that the approximation should improve with the age of the structure.

  15. Current progress and future prospects of the VITA based neutron source.

    PubMed

    Aleynik, V; Bashkirtsev, A; Kanygin, V; Kasatov, D; Kuznetsov, A; Makarov, A; Schudlo, I; Sorokin, I; Taskaev, S; Tiunov, M

    2014-06-01

    At the BINP, a pilot accelerator based epithermal neutron source is now in use. Most recent investigations on the facility are related with studying the dark current, X-ray radiation measuring, optimization of H(-)-beam injection and new gas stripping target calibrating. The results of these studies, ways of providing stability to the accelerator are presented and discussed, as well as the ways of creating the therapeutic beam and strategies of applying the facility for clinical use. PMID:24369890

  16. [Curriculum vitae aortae].

    PubMed

    Solberg, S

    1998-12-10

    The Greek word aorta means lifter. The vessel was so termed because Aristotle, who first described it, assumed that the heart was lifted by/hanging in aorta. Leonardo da Vinci described the detailed anatomy of aorta. During the 17th century our present understanding of the aorta and the circulation of blood took form due to the descriptions given by William Harvey. The first known operation for abdominal aortic aneurysm was performed in London in 1817 by Sir Astley Cooper who ligated the infrarenal aorta above the aneurysm. Puncture with needles and application of electricity were later tried in order to induce thromboses in the aneurysm. In 1948 Albert Einstein was operated with wrapping of his abdominal aneurysm with cellophane. In 1955 he suffered rupture and died after having refused operation. In 1951 the first successful operation for abdominal aortic aneurysm was performed in Paris by Charles Dubost. With slight modifications, the same operative technique is used today.

  17. In Vivo and in Vitro Evaluations of Repeatability and Accuracy of VITA Easyshade® Advance 4.0 Dental Shade-Matching Device

    PubMed Central

    Illeš, Iva Ž.; Alajbeg, Maja; Žagar

    2015-01-01

    Objectives The objective of this study was to evaluate the intra-device repeatability and accuracy of dental shade-matching device (VITA Easyshade® Advance 4.0) using both in vitro and in vivo models. Materials and methods For the repeatability assessment, the in vivo model utilized shade-matching device to measure the central region of the labial surface of right maxillary central incisors of 10 people twice. The following tooth colors were measured: B1, A1, A2, A3, C1 and C3. The in vitro model included the same six Vitapan Classical tabs. Two measurements were made of the central region of each shade tab. For the accuracy assessment, each shade tab from 3 Vitapan Classical shade guides was measured once. CIE L*a*b* values were determined. Intraclass correlation coefficients (ICCs) were used to analyze the in vitro and in vivo intra-device repeatability of the shade-matching device. The difference between in vitro and in vivo models was analyzed. Accuracy of the device tested was calculated. Results The mean color differences for in vivo and in vitro models were 3.51 and 1.25 E units, respectively. The device repeatability ICCs for in vivo measurements ranged from 0.858 to 0.971 and for in vitro from 0.992 to 0.994. Accuracy of the device tested was 93.75%. Conclusion Within the limitations of the experiment, VITA Easyshade®Advance 4.0 dental shade-matching device enabled reliable and accurate measurement. It can be a valuable tool for the determination of tooth colours.

  18. In Vivo and in Vitro Evaluations of Repeatability and Accuracy of VITA Easyshade® Advance 4.0 Dental Shade-Matching Device

    PubMed Central

    Illeš, Iva Ž.; Alajbeg, Maja; Žagar

    2015-01-01

    Objectives The objective of this study was to evaluate the intra-device repeatability and accuracy of dental shade-matching device (VITA Easyshade® Advance 4.0) using both in vitro and in vivo models. Materials and methods For the repeatability assessment, the in vivo model utilized shade-matching device to measure the central region of the labial surface of right maxillary central incisors of 10 people twice. The following tooth colors were measured: B1, A1, A2, A3, C1 and C3. The in vitro model included the same six Vitapan Classical tabs. Two measurements were made of the central region of each shade tab. For the accuracy assessment, each shade tab from 3 Vitapan Classical shade guides was measured once. CIE L*a*b* values were determined. Intraclass correlation coefficients (ICCs) were used to analyze the in vitro and in vivo intra-device repeatability of the shade-matching device. The difference between in vitro and in vivo models was analyzed. Accuracy of the device tested was calculated. Results The mean color differences for in vivo and in vitro models were 3.51 and 1.25 E units, respectively. The device repeatability ICCs for in vivo measurements ranged from 0.858 to 0.971 and for in vitro from 0.992 to 0.994. Accuracy of the device tested was 93.75%. Conclusion Within the limitations of the experiment, VITA Easyshade®Advance 4.0 dental shade-matching device enabled reliable and accurate measurement. It can be a valuable tool for the determination of tooth colours. PMID:27688393

  19. Uptake and Effects of the e-Vita Personal Health Record with Self-Management Support and Coaching, for Type 2 Diabetes Patients Treated in Primary Care.

    PubMed

    van Vugt, M; de Wit, M; Sieverink, F; Roelofsen, Y; Hendriks, S H; Bilo, H J G; Snoek, F J

    2016-01-01

    We studied the use, uptake, and effects of e-Vita, a personal health record, with self-management support and personalized asynchronized coaching, for type 2 diabetes patients treated in primary care. Patients were invited by their practice nurse to join the study aimed at testing use and effects of a personal health record. Patients were followed up for 6 months. Uptake and usage were monitored using log data. Outcomes were self-reported diabetes self-care, diabetes-related distress, and emotional wellbeing. Patients' health status was collected from their medical chart. 132 patients agreed to participate in the study of which less than half (46.1%) did not return to the personal health record after 1st login. Only 5 patients used the self-management support program within the personal health record, 3 of whom asked a coach for feedback. Low use of the personal health record was registered. No statistical significant differences on any of the outcome measures were found between baseline and 6 month follow-up. This study showed minimal impact of implementing a personal health record including self-management support in primary diabetes care. Successful adoption of web-based platforms, as ongoing patient centered care, is hard to achieve without additional strategies aimed at enhancing patient motivation and engaging professionals.

  20. Menaquinone-7 Supplementation to Reduce Vascular Calcification in Patients with Coronary Artery Disease: Rationale and Study Protocol (VitaK-CAC Trial).

    PubMed

    Vossen, Liv M; Schurgers, Leon J; van Varik, Bernard J; Kietselaer, Bas L J H; Vermeer, Cees; Meeder, Johannes G; Rahel, Braim M; van Cauteren, Yvonne J M; Hoffland, Ge A; Rennenberg, Roger J M W; Reesink, Koen D; de Leeuw, Peter W; Kroon, Abraham A

    2015-10-28

    Coronary artery calcification (CAC) develops early in the pathogenesis of atherosclerosis and is a strong and independent predictor of cardiovascular disease (CVD). Arterial calcification is caused by an imbalance in calcification regulatory mechanisms. An important inhibitor of calcification is vitamin K-dependent matrix Gla protein (MGP). Both preclinical and clinical studies have shown that inhibition of the vitamin K-cycle by vitamin K antagonists (VKA) results in elevated uncarboxylated MGP (ucMGP) and subsequently in extensive arterial calcification. This led us to hypothesize that vitamin K supplementation may slow down the progression of calcification. To test this, we designed the VitaK-CAC trial which analyses effects of menaquinone-7 (MK-7) supplementation on progression of CAC. The trial is a double-blind, randomized, placebo-controlled trial including patients with coronary artery disease (CAD). Patients with a baseline Agatston CAC-score between 50 and 400 will be randomized to an intervention-group (360 microgram MK-7) or a placebo group. Treatment duration will be 24 months. The primary endpoint is the difference in CAC-score progression between both groups. Secondary endpoints include changes in arterial structure and function, and associations with biomarkers. We hypothesize that treatment with MK-7 will slow down or arrest the progression of CAC and that this trial may lead to a treatment option for vascular calcification and subsequent CVD.

  1. Uptake and Effects of the e-Vita Personal Health Record with Self-Management Support and Coaching, for Type 2 Diabetes Patients Treated in Primary Care

    PubMed Central

    van Vugt, M.; de Wit, M.; Sieverink, F.; Roelofsen, Y.; Hendriks, S. H.; Bilo, H. J. G.; Snoek, F. J.

    2016-01-01

    We studied the use, uptake, and effects of e-Vita, a personal health record, with self-management support and personalized asynchronized coaching, for type 2 diabetes patients treated in primary care. Patients were invited by their practice nurse to join the study aimed at testing use and effects of a personal health record. Patients were followed up for 6 months. Uptake and usage were monitored using log data. Outcomes were self-reported diabetes self-care, diabetes-related distress, and emotional wellbeing. Patients' health status was collected from their medical chart. 132 patients agreed to participate in the study of which less than half (46.1%) did not return to the personal health record after 1st login. Only 5 patients used the self-management support program within the personal health record, 3 of whom asked a coach for feedback. Low use of the personal health record was registered. No statistical significant differences on any of the outcome measures were found between baseline and 6 month follow-up. This study showed minimal impact of implementing a personal health record including self-management support in primary diabetes care. Successful adoption of web-based platforms, as ongoing patient centered care, is hard to achieve without additional strategies aimed at enhancing patient motivation and engaging professionals. PMID:26955640

  2. Pathways of nitrogen assimilation in cowpea nodules studied using /sup 15/N/sub 2/ and allopurinol. [Vigna unguiculata L. Walp. cv Vita

    SciTech Connect

    Atkins, C.A.; Storer, P.J.; Pate, J.S.

    1988-01-01

    In the presence of 0.5 millimolar allopurinol (4-hydroxypyrazolo (3,4-d)pyrimidine), an inhibitor of NAD:xanthine oxidoreductase (EC 1.2.3.2), intact attached nodules of cowpea (vigna unguiculata L. Walp. cv Vita 3) formed (/sup 15/N)xanthine from /sup 15/N/sub 2/ at rates equivalent to those of ureide synthesis, confirming the direct assimilation of fixed nitrogen into purines. Xanthine accumulated in nodules and was exported in increasing amounts in xylem of allopurinol-treated plants. Other intermediates of purine oxidation, de novo purine synthesis, and ammonia assimilation did not increase and, over the time course of experiments (4 hours), allopurinol had no effect on nitrogenase (EC 1.87.99.2) activity. Negligible /sup 15/N -labeling of asparagine from /sup 15/N/sub 2/ was observed, suggesting that the significant pool (up to 14 micromoles per gram of nodule fresh weight) of this amide in cowpea nodules was not formed directly from fixation but may have accumulated as a consequence of phloem delivery.

  3. Menaquinone-7 Supplementation to Reduce Vascular Calcification in Patients with Coronary Artery Disease: Rationale and Study Protocol (VitaK-CAC Trial)

    PubMed Central

    Vossen, Liv M.; Schurgers, Leon J.; van Varik, Bernard J.; Kietselaer, Bas L. J. H.; Vermeer, Cees; Meeder, Johannes G.; Rahel, Braim M.; van Cauteren, Yvonne J. M.; Hoffland, Ge A.; Rennenberg, Roger J. M. W.; Reesink, Koen D.; de Leeuw, Peter W.; Kroon, Abraham A.

    2015-01-01

    Coronary artery calcification (CAC) develops early in the pathogenesis of atherosclerosis and is a strong and independent predictor of cardiovascular disease (CVD). Arterial calcification is caused by an imbalance in calcification regulatory mechanisms. An important inhibitor of calcification is vitamin K-dependent matrix Gla protein (MGP). Both preclinical and clinical studies have shown that inhibition of the vitamin K-cycle by vitamin K antagonists (VKA) results in elevated uncarboxylated MGP (ucMGP) and subsequently in extensive arterial calcification. This led us to hypothesize that vitamin K supplementation may slow down the progression of calcification. To test this, we designed the VitaK-CAC trial which analyses effects of menaquinone-7 (MK-7) supplementation on progression of CAC. The trial is a double-blind, randomized, placebo-controlled trial including patients with coronary artery disease (CAD). Patients with a baseline Agatston CAC-score between 50 and 400 will be randomized to an intervention-group (360 microgram MK-7) or a placebo group. Treatment duration will be 24 months. The primary endpoint is the difference in CAC-score progression between both groups. Secondary endpoints include changes in arterial structure and function, and associations with biomarkers. We hypothesize that treatment with MK-7 will slow down or arrest the progression of CAC and that this trial may lead to a treatment option for vascular calcification and subsequent CVD. PMID:26516910

  4. Retrospective clinical investigation and survival analysis on ceramic inlays and partial ceramic crowns: results up to 7 years.

    PubMed

    Felden, A; Schmalz, G; Federlin, M; Hiller, K A

    1998-12-01

    This study retrospectively evaluated the clinical performance of 287 all-ceramic restorations placed during routine patient care in the University setting in the past 7 years. All patients (n = 106) with ceramic inlays or partial ceramic crowns (PCC), placed during 1988-1994 (n = 327) by five experienced dentists were asked to take part in a clinical investigation, and 92 patients with 287 restorations (232 inlays, 55 PCC) agreed to do so. The following ceramics were used: 44 (15.3%) Dicor (Dentsply), 126 (43.9%) IPS-Empress (Ivoclar), 82 (28.7%) Mirage II, 33 (11.5%) Cerec-Vita-Mark 1 (Vita), and 2 (0.7%) Duceram LFC (Ducera) restorations. The restorations were placed using the following luting composites: 73 (25.4%) Dual Cure Luting Cement (Optec), 81 (28.3%) Variolink high viscosity (Ivoclar), 32 (11.1%) Microfill Pontic C (Kulzer), 51 (17.8%) Dual Zement (Ivoclar), 40 (13.9%) Dicor Light Activated Cement (Dentsply), and 10 (3.5%) Vita Cerec Duo Cement (Vita). Restorations were evaluated according to the modified USPHS criteria. Kaplan-Meier analysis was used to calculate the probability of survival. Of the 287 restorations 270 (94.2%) were still in function without any need of intervention. Fourteen restorations (4.8%) had failed before starting the clinical investigation, and in three a fracture was found during the investigation. These 17 failed restorations consisted of 14 PCC and 3 ceramic inlays. The results of the clinical investigation revealed 59.2% Alpha-ratings for marginal adaptation. Only one restored tooth showed recurrent caries. The probability of survival (95% confidence interval) for 7 years was 98% (97.99-98.01%) for ceramic inlays and 56% (46-66%) for PCC. Our findings show that ceramic inlays can be regarded as an acceptable alternative to cast gold restorations within the methodological limitations of the present study. For PCC further experience with more recent ceramics is warranted.

  5. Differences Between Patients With Type 2 Diabetes Mellitus Interested and Uninterested in the Use of a Patient Platform (e-VitaDM-2/ZODIAC-41).

    PubMed

    Roelofsen, Yvonne; Hendriks, Steven H; Sieverink, Floor; Landman, Gijs W D; Groenier, Klaas H; Bilo, Henk J G; Kleefstra, Nanne

    2014-02-21

    The prevalence of type 2 diabetes mellitus (T2DM) is rising in the Netherlands, and health care's workload will increase. e-Health applications may increase patients' participation in their care and could help reducing workload. To explore potential users, differences in patients interested and uninterested in e-Health are characterized. A prospective cohort study was initiated in the Drenthe region of the Netherlands. This study included inviting T2DM patients to use e-Health (the e-Vita platform). Patients were offered access to clinical data, laboratory results, educational modules, and a self-management support program. Data were obtained from health record systems of general practices and questionnaires. Out of 2674 patients, 1378 (51.5%) participated in the study. Of the 1378 patients, 974 (70.7%) were interested in e-Health. Of 974, 405 (41.6%) were registered for e-Health. Interested patients were more often male, were younger, had shorter T2DM duration, and were higher educated. Of 405, 110 (27.2%) used the e-Health. No differences were found between users and nonusers of e-Health. Patients interested in e-Health were more often male, were younger, had shorter T2DM duration, and were more often higher educated. However, even in this interested group, the actual participation rate remained low. Together with characteristics and attitudes of caregivers and T2DM patients, the look and content of the e-Health platform strategies that increase interest and participation need to be developed.

  6. Differences Between Patients With Type 2 Diabetes Mellitus Interested and Uninterested in the Use of a Patient Platform (e-VitaDM-2/ZODIAC-41).

    PubMed

    Roelofsen, Yvonne; Hendriks, Steven H; Sieverink, Floor; Landman, Gijs W D; Groenier, Klaas H; Bilo, Henk J G; Kleefstra, Nanne

    2014-02-21

    The prevalence of type 2 diabetes mellitus (T2DM) is rising in the Netherlands, and health care's workload will increase. e-Health applications may increase patients' participation in their care and could help reducing workload. To explore potential users, differences in patients interested and uninterested in e-Health are characterized. A prospective cohort study was initiated in the Drenthe region of the Netherlands. This study included inviting T2DM patients to use e-Health (the e-Vita platform). Patients were offered access to clinical data, laboratory results, educational modules, and a self-management support program. Data were obtained from health record systems of general practices and questionnaires. Out of 2674 patients, 1378 (51.5%) participated in the study. Of the 1378 patients, 974 (70.7%) were interested in e-Health. Of 974, 405 (41.6%) were registered for e-Health. Interested patients were more often male, were younger, had shorter T2DM duration, and were higher educated. Of 405, 110 (27.2%) used the e-Health. No differences were found between users and nonusers of e-Health. Patients interested in e-Health were more often male, were younger, had shorter T2DM duration, and were more often higher educated. However, even in this interested group, the actual participation rate remained low. Together with characteristics and attitudes of caregivers and T2DM patients, the look and content of the e-Health platform strategies that increase interest and participation need to be developed. PMID:24876572

  7. Sediment dynamics in the Adriatic Sea investigated with coupled models

    USGS Publications Warehouse

    Sherwood, Christopher R.; Book, Jeffrey W.; Carniel, Sandro; Cavaleri, Luigi; Chiggiato, Jacopo; Das, Himangshu; Doyle, James D.; Harris, Courtney K.; Niedoroda, Alan W.; Perkins, Henry; Poulain, Pierre-Marie; Pullen, Julie; Reed, Christopher W.; Russo, Aniello; Sclavo, Mauro; Signell, Richard P.; Traykovski, Peter A.; Warner, John C.

    2004-01-01

    Several large research programs focused on the Adriatic Sea in winter 2002-2003, making it an exciting place for sediment dynamics modelers (Figure 1). Investigations of atmospheric forcing and oceanic response (including wave generation and propagation, water-mass formation, stratification, and circulation), suspended material, bottom boundary layer dynamics, bottom sediment, and small-scale stratigraphy were performed by European and North American researchers participating in several projects. The goal of EuroSTRATAFORM researchers is to improve our ability to understand and simulate the physical processes that deliver sediment to the marine environment and generate stratigraphic signatures. Scientists involved in the Po and Apennine Sediment Transport and Accumulation (PASTA) experiment benefited from other major research programs including ACE (Adriatic Circulation Experiment), DOLCE VITA (Dynamics of Localized Currents and Eddy Variability in the Adriatic), EACE (the Croatian East Adriatic Circulation Experiment project), WISE (West Istria Experiment), and ADRICOSM (Italian nowcasting and forecasting) studies.

  8. Demographical, Clinical, and Psychological Characteristics of Users and Nonusers of an Online Platform for T2DM Patients (e-VitaDM-3/ZODIAC-44)

    PubMed Central

    Roelofsen, Yvonne; van Vugt, Michael; Hendriks, Steven H.; van Hateren, Kornelis J. J.; Groenier, Klaas H.; Snoek, Frank J.; Kleefstra, Nanne; Huijsman, Robbert; Bilo, Henk J. G.

    2016-01-01

    Background. Online platforms offer opportunities for support in changing lifestyle and taking responsibility for one's health, but engaging patients with type 2 diabetes is challenging. Previous studies have shown that patients interested in platforms were more often male, younger, and higher educated. This study aims to investigate differences in clinical and psychological characteristics between users and nonusers of a newly developed platform. Methods. A prospective study started in the Drenthe region of Netherlands. Participants in the study concerning quality of care and quality of life were additionally invited to use the platform. Results. 633 patients were registered after they opted for platform use. Of these patients, 361 (57.0%) never logged on, 184 (29.1%) were labeled “curious” users, and 88 (13.9%) were identified as “active” users. Users had lower HbA1c levels and more often hypertension compared to nonusers, and reported higher quality of life, better well-being, lower diabetes-related distress, and better medication adherence. Discussion. Platform use was associated with more favorable clinical and psychological characteristics relative to nonuse. Those with greater severity of disease, lower mood, and progression of disease used the platform the least. Other approaches need to be developed to reach these patients. Furthermore, improving the platform could also help to reach them. This trial is registered with Clinicaltrials.gov NCT01570140. PMID:26682232

  9. Using the Curriculum Vitae in Leadership Research

    ERIC Educational Resources Information Center

    Bawazeer, Wazerah; Gunter, Helen M

    2016-01-01

    Professional biography research with those who hold formal positions in educational organizations is an established approach to researching leaders, leading and leadership. A key focus is on the oral account of a life story, and this can include family and wider life experiences. What is less of a feature is how the respondent codifies their…

  10. The curriculum vitae: gateway to academia.

    PubMed

    Christenbery, Tom L

    2014-01-01

    A CV serves as formal documentation of the applicant’s career path and provides necessary demographic and historical information for career change or advancement. Therefore, each section of the CV should be a thorough accounting of the applicant’s academic, work, and professional responsibilities and attainments. The guidelines in this column also are relevant for nurse educators applying for positions in schools of nursing.

  11. ETINDE. Improving the role of a methodological approach and ancillary ethnoarchaeological data application for place vulnerability and resilience to a multi-hazard environment: Mt. Cameroon volcano case study [MIA-VITA project -FP7-ENV-2007-1

    NASA Astrophysics Data System (ADS)

    Ilaria Pannaccione Apa, Maria; Kouokam, Emmanuel; Mbe Akoko, Robert; Peppoloni, Silvia; Fabrizia Buongiorno, Maria; Thierry, Pierre

    2013-04-01

    The FP7 MIA-VITA [Mitigate and assess risk from volcanic impact on terrain and human activities] project has been designed to address multidisciplinary aspects of volcanic threat assessment and management from prevention to crisis management recovery. In the socio-economic analysis carried out at Mt. Cameroon Bakweri and Bakossi ethnic groups, ancillary ethnoarchaeological information has been included to point out the cultural interaction between the volcano and its residents. In 2009-2011, ethnoanthropological surveys and interviews for data collection were carried out at Buea, Limbe, West Coast, Tiko and Muyuka sub-divisions adjacent to Mt. Cameroon. One of the outstanding, results from the Bakweri and Bakossi cultural tradition study: natural hazards are managed and produced by supernatural forces, as: Epasa Moto, God of the Mountain (Mt. Cameroon volcano) and Nyango Na Nwana , Goddess of the sea (Gulf of Guinea). In the case of Mount Cameroon, people may seek the spirit or gods of the mountain before farming, hunting and most recently the undertaking of the Mount Cameroon annual race are done. The spirit of this mountain must be seek to avert or stop a volcanic eruption because the eruption is attributed to the anger of the spirit. Among the Northern Bakweri, the association of spirits with the mountain could also be explained in terms of the importance of the mountain to the people. Most of their farming and hunting is done on the Mountain. Some forest products, for instance, wood for building and furniture is obtained from the forest of the mountain; this implies that the people rely on the Mountain for food, game and architecture/furniture etc. In addition, the eruption of the mountain is something which affects the people. It does not only destroy property, it frustrates people and takes away human lives when it occurs. Because of this economic importance of the Mountain and its unexpected and unwanted eruption, the tendency is to believe that it has some

  12. Watershed Investigations

    ERIC Educational Resources Information Center

    Bodzin, Alec; Shive, Louise

    2004-01-01

    Investigating local watersheds presents middle school students with authentic opportunities to engage in inquiry and address questions about their immediate environment. Investigation activities promote learning in an investigations interdisciplinary context as students explore relationships among chemical, biological, physical, geological, and…

  13. Forensics Investigator

    MedlinePlus

    ... Careers Career Profiles Forensics Investigator Overview Description Forensic science technicians investigate crimes by collecting and analyzing physical evidence. Often, they specialize in areas such as ...

  14. Coping with investigators and investigations.

    PubMed

    Stewart, D O; Fee, M K

    1991-09-01

    Most businesses in highly regulated industries like health care are likely to face an investigation at some point. By knowing ahead of time how to properly respond to investigators' requests and by exercising caution during the investigation, health care agencies can minimize the potential damage.

  15. Fire investigation

    NASA Astrophysics Data System (ADS)

    Gomberg, A.

    There was considerable progress made on several fronts of fire investigation in the United States in recent years. Progress was made in increasing the quantity of fire investigation and reporting, through efforts to develop the National Fire Incident Reporting System. Improving overall quality of fire investigation is the objective of efforts such as the Fire Investigation Handbook, which was developed and published by the National Bureau of Standards, and the upgrading and expanding of the ""dictionary'' of fire investigation and reporting, the NFPA 901, Uniform Coding for Fire Protection, system. The science of fire investigation as furthered also by new approaches to post fire interviews being developed at the University of Washington, and by in-depth research into factors involved in several large loss fires, including the MGM Grand Hotel in Las Vegas. Finally, the use of special study fire investigations - in-depth investigations concentrating on specific fire problems - is producing new glimpses into the nature of the national fire problem. A brief description of the status of efforts in each of these areas is discussed.

  16. Quaternary investigation

    SciTech Connect

    Stieve, A.

    1991-05-15

    The primary purpose of the Quaternary investigation is to provide information on the location and age of Quaternary deposits for use in evaluating the presence or absence of neotectonic deformation or paleoliquefaction features within the Savannah River Site (SRS) region. The investigation will provide a basis for evaluating the potential for capable faults and associated deformation in the SRS vicinity. Particular attention will be paid to the Pen Branch fault.

  17. Viatical investigation.

    PubMed

    1995-10-01

    Viatical Benefits, a viatical settlement company in Fort Lauderdale, FL, is reportedly under investigation by the Securities and Exchange Commission (SEC) for using high-pressure sales tactics to sell policies to investors. The SEC has declined comment, and Egbert Jaeger, the president of Viatical Benefits, has denied any investigation. This investigation follows a preliminary injunction filed by a Federal judge against Life Partners Inc. of Waco, TX, in August. The SEC claimed that Life Partners repackaged life insurance contracts as securities for investors, in violation of Federal securities laws. Viatical settlements enable persons with HIV to sell their life insurance policies at a discount, providing clients with sixty to eighty percent of the face value in cash to use for living expenses. Viatical settlement companies usually act as brokers in the sale of the policies. PMID:11362822

  18. Investigation Organizer

    NASA Technical Reports Server (NTRS)

    Panontin, Tina; Carvalho, Robert; Keller, Richard

    2004-01-01

    Contents include the folloving:Overview of the Application; Input Data; Analytical Process; Tool's Output; and Application of the Results of the Analysis.The tool enables the first element through a Web-based application that can be accessed by distributed teams to store and retrieve any type of digital investigation material in a secure environment. The second is accomplished by making the relationships between information explicit through the use of a semantic network-a structure that literally allows an investigator or team to "connect -the-dots." The third element, the significance of the correlated information, is established through causality and consistency tests using a number of different methods embedded within the tool, including fault trees, event sequences, and other accident models. And finally, the evidence gathered and structured within the tool can be directly, electronically archived to preserve the evidence and investigative reasoning.

  19. Laboratory investigations

    NASA Astrophysics Data System (ADS)

    1984-09-01

    The primary objectives were to examine the site-specific physical, chemical, and biological factors that impact construction, durability and performance of the proposed 5-MW (sub e) solar pond system at the Salton Sea. The interactions of the water, salt, and soil of the site and on material compatibility were examined. Potential interactions of the water/brine and soil are particularly important because the pond will utilize the naturally occurring clays as a bottom seal. Although there is a considerable and growing solar pond literature, little written information deals with the important site-specific investigations of water, salt, and soil. Therefore, technical effort was directed toward identifying the factors that should be investigated and determining methods of investigation. As a result, a by-product was the development of an approach for site-specific investigations and some specific methodologies. This development should continue in order to establish a generic approach for evaluating the suitability of any site for the construction of large-scale solar ponds.

  20. A curriculum vitae of teeth: evolution, generation, regeneration.

    PubMed

    Koussoulakou, Despina S; Margaritis, Lukas H; Koussoulakos, Stauros L

    2009-01-01

    The ancestor of recent vertebrate teeth was a tooth-like structure on the outer body surface of jawless fishes. Over the course of 500,000,000 years of evolution, many of those structures migrated into the mouth cavity. In addition, the total number of teeth per dentition generally decreased and teeth morphological complexity increased. Teeth form mainly on the jaws within the mouth cavity through mutual, delicate interactions between dental epithelium and oral ectomesenchyme. These interactions involve spatially restricted expression of several, teeth-related genes and the secretion of various transcription and signaling factors. Congenital disturbances in tooth formation, acquired dental diseases and odontogenic tumors affect millions of people and rank human oral pathology as the second most frequent clinical problem. On the basis of substantial experimental evidence and advances in bioengineering, many scientists strongly believe that a deep knowledge of the evolutionary relationships and the cellular and molecular mechanisms regulating the morphogenesis of a given tooth in its natural position, in vivo, will be useful in the near future to prevent and treat teeth pathologies and malformations and for in vitro and in vivo teeth tissue regeneration.

  1. [Historia magistra vitae: on the methods of historical demography].

    PubMed

    Botev, N

    1992-01-01

    Indirect estimation techniques are applied to data for Bulgaria from 1891 to 1958 to assess trends in population dynamics. An interdisciplinary approach is suggested for the study of countries where data are often incomplete. (SUMMARY IN ENG AND RUS)

  2. A Curriculum Vitae of Teeth: Evolution, Generation, Regeneration

    PubMed Central

    Koussoulakou, Despina S.; Margaritis, Lukas H.; Koussoulakos, Stauros L.

    2009-01-01

    The ancestor of recent vertebrate teeth was a tooth-like structure on the outer body surface of jawless fishes. Over the course of 500,000,000 years of evolution, many of those structures migrated into the mouth cavity. In addition, the total number of teeth per dentition generally decreased and teeth morphological complexity increased. Teeth form mainly on the jaws within the mouth cavity through mutual, delicate interactions between dental epithelium and oral ectomesenchyme. These interactions involve spatially restricted expression of several, teeth-related genes and the secretion of various transcription and signaling factors. Congenital disturbances in tooth formation, acquired dental diseases and odontogenic tumors affect millions of people and rank human oral pathology as the second most frequent clinical problem. On the basis of substantial experimental evidence and advances in bioengineering, many scientists strongly believe that a deep knowledge of the evolutionary relationships and the cellular and molecular mechanisms regulating the morphogenesis of a given tooth in its natural position, in vivo, will be useful in the near future to prevent and treat teeth pathologies and malformations and for in vitro and in vivo teeth tissue regeneration. PMID:19266065

  3. The Representation of Oral Culture in the "Vita Constantini."

    ERIC Educational Resources Information Center

    Butler, Francis

    1995-01-01

    Examines a passage describing an encounter between the missionary, Saint Constantine-Cyril, and a pagan in the land of the Khazars. The main focus of the saint's discourse emphasized that without inventing the Slavic alphabet, he would have had no hope of success as a missionary. (24 references) (CK)

  4. Purposeful Statistical Investigations

    ERIC Educational Resources Information Center

    Day, Lorraine

    2014-01-01

    Lorraine Day provides us with a great range of statistical investigations using various resources such as maths300 and TinkerPlots. Each of the investigations link mathematics to students' lives and provide engaging and meaningful contexts for mathematical inquiry.

  5. Investigations with Protease.

    ERIC Educational Resources Information Center

    Yip, Din Yan

    1997-01-01

    Presents two simple and reliable ways for measuring protease activity that can be used for a variety of investigations in a range of biology class levels. The investigations use protease from a variety of sources. (DDR)

  6. Success with Investigations.

    ERIC Educational Resources Information Center

    Chin, Christine

    2003-01-01

    Describes strategies for facilitating student science investigations and alleviating common weaknesses associated with student performance. Includes checklist criteria for performance on investigative tasks and an example of an assessment rubric for the investigation of the effect of temperature on enzyme activity. (Author/KHR)

  7. Investigating Encrypted Material

    NASA Astrophysics Data System (ADS)

    McGrath, Niall; Gladyshev, Pavel; Kechadi, Tahar; Carthy, Joe

    When encrypted material is discovered during a digital investigation and the investigator cannot decrypt the material then s/he is faced with the problem of how to determine the evidential value of the material. This research is proposing a methodology of extracting probative value from the encrypted file of a hybrid cryptosystem. The methodology also incorporates a technique for locating the original plaintext file. Since child pornography (KP) images and terrorist related information (TI) are transmitted in encrypted format the digital investigator must ask the question Cui Bono? - who benefits or who is the recipient? By doing this the scope of the digital investigation can be extended to reveal the intended recipient.

  8. Crime Scene Investigation.

    ERIC Educational Resources Information Center

    Harris, Barbara; Kohlmeier, Kris; Kiel, Robert D.

    Casting students in grades 5 through 12 in the roles of reporters, lawyers, and detectives at the scene of a crime, this interdisciplinary activity involves participants in the intrigue and drama of crime investigation. Using a hands-on, step-by-step approach, students work in teams to investigate a crime and solve a mystery. Through role-playing…

  9. Sea Anemone: Investigations.

    ERIC Educational Resources Information Center

    Hunt, John D.

    1982-01-01

    Several investigations can be undertaken with live sea anemones. A sea anemone's feeding response, fighting power, color, and symbiotic relationships to other invertebrates (such as a marine hermit crab) can be investigated in the high school classroom. Background information and laboratory procedures are provided. (Author/JN)

  10. Vamistor resistor investigation

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Results are presented of the failure investigation conducted on resistors produced by the Vamistor Divison, Wagner Electric Corporation. This failure investigation included; failure analyses, chemical and metallurgical analyses, failure mechanism studies, seal leak analyses, and nondestructive stress tests. The data, information, conclusions, and recommendation can be helpful in assessing current usage of these resistors.

  11. Investigations in Martian Sedimentology

    NASA Technical Reports Server (NTRS)

    Moore, Jeffrey M.

    1998-01-01

    The purpose of this report is to investigate and discuss the Martian surface. This report was done in specific tasks. The tasks were: characterization of Martian fluids and chemical sediments; mass wasting and ground collapse in terrains of volatile-rich deposits; Mars Rover terrestrial field investigations; Mars Pathfinder operations support; and Martian subsurface water instrument.

  12. Skylab EREP Investigations Summary

    NASA Technical Reports Server (NTRS)

    Pierson, W. J. (Editor)

    1978-01-01

    The problems in the areas of agriculture, range and forestry; land use and cartography; geology and hydrology; oceans atmosphere, and data analysis techniques were investigated and summarized using Earth Resources Experiment Package (EREP) data.

  13. Access to Investigational Drugs

    MedlinePlus

    ... drug if the supply is limited and the demand is high. Are all investigational drugs available through ... be limited in part by drug supply, patient demand, or other factors. What is NCI’s role in ...

  14. Outbreaks and Investigations

    MedlinePlus

    ... Rhizopus Investigation web page. Histoplasmosis in an Illinois Prison Histoplasmosis outbreak at a state prison in Illinois, ... Department of Corrections Coccidioidomycosis (Valley fever) in California Prisons High rates of coccidioidomycosis (Valley fever) at two ...

  15. Student Investigations Using Chromatography

    ERIC Educational Resources Information Center

    Witters, Weldon L.; Bush, Kenneth

    1970-01-01

    Three different problems are given for student investigation in determining amino acid compositions, floral pigments, and water soluble amino acids by using the techniques of Roll Chromotography, DISC Chromotography, Thin Layer, and Paper Chromotography. (BR)

  16. NASA guest investigators

    NASA Astrophysics Data System (ADS)

    The National Aeronautics and Space Administration (NASA) is now seeking guest investigators to participate in the International Sun-Earth Explorer (ISEE) and International Cometary Explorer (ICE) programs. The ISEE/ICE project is a joint NASA/European Space Agency (ESA) venture. A budget of approximately $500,000 to support the ISEE/ICE Guest Investigator Program is expected for fiscal year 1985, and a similar amount is expected for FY 1986.Although NASA welcomes proposals at any time, proposals must be received by mid-October in order to be considered in the initial selection. Those arriving after mid-November may be held for another selection period.

  17. Systems special investigation group

    NASA Technical Reports Server (NTRS)

    1991-01-01

    An interim report concerning the Long Duration Exposure Facility (LDEF) is presented by a Boeing Systems special investigation group (SIG). The SIG activities were divided into five engineering disciplines: electrical, mechanical, optics, thermal, and batteries/solar cells. The responsibilities of the SIG included the following areas: support de-integration at Kennedy Space Center (KSC); testing of hardware at Boeing; review of principal investigator (PI) test plans and test results; support of test activities at PI labs; and collation of all test results into the SIG database.

  18. Seasonal Change Investigations

    ERIC Educational Resources Information Center

    Smith, Wendy

    2009-01-01

    The author describes how the yearlong Investigating Seasonal Change at North Ponds project enabled third-grade students to take on the role of environmental scientists, recording and analyzing environmental data from ponds near their school. The students used an array of technological tools to explore and report on the causes and effects of…

  19. Investigating Ramps and Sliders.

    ERIC Educational Resources Information Center

    Malone, Mark R.

    1986-01-01

    Offers a series of hands-on activities for introducing students to concepts of energy transfer and conversion. Describes how simple devices as marbles, ramps, and sliders can be used to gauge the transfer of energy and assist in the development of investigative skills. (ML)

  20. Investigations into Character Enhancement.

    ERIC Educational Resources Information Center

    Hartoonian, H. Michael

    2001-01-01

    Presents six different investigations of character enhancement that attempts to answer three questions: (1) who are you; (2) what is your destination; and (3) who is your captain? Intends to build relationships among ideas such as perspective taking, seeing and making connections with the other, and understanding more about ethical development.…

  1. Sequences for Student Investigation

    ERIC Educational Resources Information Center

    Barton, Jeffrey; Feil, David; Lartigue, David; Mullins, Bernadette

    2004-01-01

    We describe two classes of sequences that give rise to accessible problems for undergraduate research. These problems may be understood with virtually no prerequisites and are well suited for computer-aided investigation. The first sequence is a variation of one introduced by Stephen Wolfram in connection with his study of cellular automata. The…

  2. Ice Core Investigations

    ERIC Educational Resources Information Center

    Krim, Jessica; Brody, Michael

    2008-01-01

    What can glaciers tell us about volcanoes and atmospheric conditions? How does this information relate to our understanding of climate change? Ice Core Investigations is an original and innovative activity that explores these types of questions. It brings together popular science issues such as research, climate change, ice core drilling, and air…

  3. Charles Darwin's Botanical Investigations

    ERIC Educational Resources Information Center

    Harley, Suzanne M.

    2010-01-01

    Charles Darwin's botanical studies provide a way to expose students to his work that followed the publication of "On the Origin of Species." We can use stories from his plant investigations to illustrate key concepts in the life sciences and model how questions are asked and answered in science.

  4. Investigating Children's Mathematics Readiness

    ERIC Educational Resources Information Center

    Lee, Joohi; Autry, Mary Murray; Fox, Jill; Williams, Cynthia

    2008-01-01

    A sample of 244 children (average age: 61 months) and their parents from the Dallas and Fort Worth (DFW) metroplex area in Texas were surveyed to investigate children's mathematics readiness. This study was conducted as part of a project funded by a local child care council, composed of business, civic, and education leaders in the community. The…

  5. Endocrine investigation and therapy.

    PubMed

    McClure, R D

    1987-08-01

    The most commonly investigated testicular disorder is male infertility. Although endocrine causes are uncommon, they are potentially curable. A careful history and examination for subtle features of hypogonadism are important initiating steps. Understanding the appropriate use of both baseline and dynamic testing of the hypothalamic-pituitary-gonadal axis (and, in certain instances, the adrenal and thyroid glands) is extremely important.

  6. Acid Rain Investigations.

    ERIC Educational Resources Information Center

    Hugo, John C.

    1992-01-01

    Presents an activity in which students investigate the formation of solid ammonium chloride aerosol particles to help students better understand the concept of acid rain. Provides activity objectives, procedures, sample data, clean-up instructions, and questions and answers to help interpret the data. (MDH)

  7. Investigating Test Bias.

    ERIC Educational Resources Information Center

    Hoepfner, Ralph; Strickland, Guy P.

    This study investigates the question of test bias to develop an index of the appropriateness of a test to a particular socioeconomic or racial-ethnic group. Bias is defined as an item by race interaction in an analysis-of-variance design. The sample of 172 third graders at two integrated schools in a large California school district, included 26…

  8. The Polar Insulation Investigation

    ERIC Educational Resources Information Center

    Urban-Rich, Juanita

    2006-01-01

    In this article, the author developed an activity called "The Polar Insulation Investigation." This activity builds on students' natural interest in "things polar" and introduces them to animal adaptations in a unique way. The aim of the exploration is to determine the role of animal coverings (e.g., blubber, fur, and feathers) and to see which is…

  9. Civil aircraft accident investigation.

    PubMed

    Haines, Daniel

    2013-01-01

    This talk reviews some historic aircraft accidents and some more recent. It reflects on the division of accident causes, considering mechanical failures and aircrew failures, and on aircrew training. Investigation results may lead to improved aircraft design, and to appropriate crew training. PMID:24057309

  10. Investigating Ocean Pollution.

    ERIC Educational Resources Information Center

    LeBeau, Sue

    1998-01-01

    Describes a fifth-grade class project to investigate two major forms of ocean pollution: plastics and oil. Students work in groups and read, discuss, speculate, offer opinions, and participate in activities such as keeping a plastics journal, testing the biodegradability of plastics, and simulating oil spills. Activities culminate in…

  11. Magsat investigation. [Canadian shield

    NASA Technical Reports Server (NTRS)

    Hall, D. H. (Principal Investigator)

    1980-01-01

    A computer program was prepared for modeling segments of the Earth's crust allowing for heterogeneity in magnetization in calculating the Earth's field at Magsat heights. This permits investigation of a large number of possible models in assessing the magnetic signatures of subprovinces of the Canadian shield. The fit between the model field and observed fields is optimized in a semi-automatic procedure.

  12. Wind, An Environmental Investigation.

    ERIC Educational Resources Information Center

    Minnesota Environmental Sciences Foundation, Inc., Minneapolis.

    An environmental investigation into how wind behaves is formulated in this unit for grades three through six. The thrust is to get students more aware of the environment in which they live, seeing how their lives are intertwined with all the elements. Specifically, knowing how the wind behaves may lead to a better understanding of how to behave…

  13. Investigating Your Environment.

    ERIC Educational Resources Information Center

    Forest Service (USDA), Washington, DC.

    The goal of this interdisciplinary curriculum is to enable students to make informed and responsible decisions about natural resources management by promoting an understanding of natural, social, and economic environments and the student's role in affecting all three. The included investigations utilize processes and techniques that help people…

  14. Investigating the Tallgrass Prairie

    ERIC Educational Resources Information Center

    Burns, Marcia V.; Chi, Sojin Y.; Hertzog, Nancy B.

    2008-01-01

    This article describes an investigation of a tallgrass prairie undertaken by 3- through 7-year-old children in a preschool and a combined kindergarten/first-grade classroom at a Midwestern university. The teaching teams were curious about how these two age groups would explore their questions about the prairie--how their questions would differ by…

  15. Soil, An Environmental Investigation.

    ERIC Educational Resources Information Center

    National Wildlife Federation, Washington, DC.

    This environmental unit is one of a series designed for integration within an existing curriculum. The unit is self-contained and requires minimal teacher preparation. The philosophy of the series is based on an experience-oriented process that encourages self-paced independent student work. This particular unit investigates soil in relation to…

  16. Best Practice -- Subsurface Investigations

    SciTech Connect

    Clark Scott

    2010-03-01

    These best practices for Subsurface Survey processes were developed at the Idaho National Laboratory (INL) and later shared and formalized by a sub-committee, under the Electrical Safety Committee of EFCOG. The developed best practice is best characterized as a Tier II (enhanced) survey process for subsurface investigations. A result of this process has been an increase in the safety and lowering of overall cost, when utility hits and their related costs are factored in. The process involves improving the methodology and thoroughness of the survey and reporting processes; or improvement in tool use rather than in the tools themselves. It is hoped that the process described here can be implemented at other sites seeking to improve their Subsurface Investigation results with little upheaval to their existing system.

  17. Site investigation for Magnus

    SciTech Connect

    Semple, R.M.; Rigden, W.J.

    1983-05-01

    In April 1982, BP's Magnus structure was installed about 150 km northeast of the Shetland Islands. The most northerly, deepest water platform in the North Sea, the steel tower is supported on groups of 2 m diameter piles that were driven, in good accordance with predictions, to an average penetration of 85 m in strong cohesive soils. The paper describes investigations performed at the platform site, and documents soil characteristics for conventional and state of the art pile analyses. Reference is made to several innovative techniques first used at the Magnus site that have since been incorporated into the larger North Sea investigations. Information is given about the geological history of the site. Test results are presented on soil strength and stiffness, including critical state soil mechanics parameters, on residual pore pressures after sampling, and on the effect of sample size on strength characteristics.

  18. Geophysical investigations in Jordan

    USGS Publications Warehouse

    Kovach, R.L.; Andreasen, G.E.; Gettings, M.E.; El-Kaysi, K.

    1990-01-01

    A number of geophysical investigations have been undertaken in the Hashemite Kingdom of Jordan to provide data for understanding the tectonic framework, the pattern of seismicity, earthquake hazards and geothermal resources of the country. Both the historical seismic record and the observed recent seismicity point to the dominance of the Dead Sea Rift as the main locus of seismic activity but significant branching trends and gaps in the seismicity pattern are also seen. A wide variety of focal plane solutions are observed emphasizing the complex pattern of fault activity in the vicinity of the rift zone. Geophysical investigations directed towards the geothermal assessment of the prominent thermal springs of Zerga Ma'in and Zara are not supportive of the presence of a crustal magmatic source. ?? 1990.

  19. FCS Technology Investigation Overview

    NASA Technical Reports Server (NTRS)

    Budinger, James; Gilbert, Tricia

    2007-01-01

    This working paper provides an overview of the Future Communication Study (FCS) technology investigation progress. It includes a description of the methodology applied to technology evaluation; evaluation criteria; and technology screening (down select) results. A comparison of screening results with other similar technology screening activities is provided. Additional information included in this working paper is a description of in-depth studies (including characterization of the L-band aeronautical channel; L-band deployment cost assessment; and performance assessments of candidate technologies in the applicable aeronautical channel) that have been conducted to support technology evaluations. The paper concludes with a description on-going activities leading to conclusion of the technology investigation and the development of technology recommendations.

  20. Rocket Motor Microphone Investigation

    NASA Technical Reports Server (NTRS)

    Pilkey, Debbie; Herrera, Eric; Gee, Kent L.; Giraud, Jerom H.; Young, Devin J.

    2010-01-01

    At ATK's facility in Utah, large full-scale solid rocket motors are tested. The largest is a five-segment version of the reusable solid rocket motor, which is for use on the Ares I launch vehicle. As a continuous improvement project, ATK and BYU investigated the use of microphones on these static tests, the vibration and temperature to which the instruments are subjected, and in particular the use of vent tubes and the effects these vents have at low frequencies.

  1. Ball Lightning Investigations

    NASA Astrophysics Data System (ADS)

    Bychkov, V. L.; Nikitin, A. I.; Dijkhuis, G. C.

    Ball lightning (BL) researches' review and theoretical models of three different authors are presented. The general review covers investigations from 1838 until the present day, and includes a discussion on observation data, experimental modeling, and theoretical approaches. Section 6.1 is written by Bychkov and Nikitin; authors of the sections 6.2, 6.3 and 6.4 are, respectively, Bychkov, Nikitin and Dijkhuis.

  2. Genesis Failure Investigation Report

    NASA Technical Reports Server (NTRS)

    Klein, John

    2004-01-01

    The-Genesis mission to collect solar-wind samples and return them to Earth for detailed analysis proceeded successfully for 3.5 years. During reentry on September 8, 2004, a failure in the entry, descent and landing sequence resulted in a crash landing of the Genesis sample return capsule. This document describes the findings of the avionics sub-team that supported the accident investigation of the JPL Failure Review Board.

  3. STS investigators' guide

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The capability of the Space Transportation System (STS), the Space Shuttle, to support crew tended and free flyer research in low Earth orbit has opened new possibilities for science in space. For the first time, research equipment can be put into orbit routinely, operated in either a shirtsleeve environment or exposed to space, and then returned to the investigator. NASA, operator of the Shuttle, has implemented a variety of programs to ensure that anyone with a worthy research idea can take advantage of this opportunity. Investigators ranging from high school students to renowned space scientists have already used the Shuttle as a platform for making Earth, atmospheric, and astronomical observations; for performing space plasma physics measurements; and for exploring the effects of microgravity on living organisms and physical processes. For investigators considering a flight experiment for the first time, this guide explains what the Shuttle has to offer, how to arrange to fly an experiment, and what to expect once preparations for the flight are under way.

  4. Investigating photonic quantum computation

    NASA Astrophysics Data System (ADS)

    Myers, Casey Robert

    The use of photons as qubits is a promising implementation for quantum computation. The inability of photons to interact, especially with the environment, makes them an ideal physical candidate. However, this also makes them a difficult system to perform two qubit gates on. Recent breakthroughs in photonic quantum computing have shown methods around the requirement of direct photon-photon interaction. In this thesis we study three recently discovered schemes for optical quantum computation. We first investigate the so called linear optical quantum computing (LOQC) scheme, exploring a method to improve the original proposal by constructing a photon-number QND detector that succeeds with a high probability. In doing this we present a new type of LOQC teleporter, one that can detect the presence of a single photon in an arbitrary polarisation state when the input state is a sum of vacuum and multi-photon terms. This new type of teleporter is an improvement on the original scheme in that the entangled states required can be made offline with fewer entangling operations. We next investigate the so called quantum bus (qubus) scheme for photonic quantum computing. We show a scheme to measure the party of n qubit states by using a single qubus mode, controlled rotations and displacements. This allows for the syndrome measurements of any stabilizer quantum error correcting code. We extend these results to a fault tolerant scheme to measure an arbitrary Pauli operator of weight n, incorporating so called single bit teleportations. We investigate the construction of a Toffoli gate by using a single qubus mode, controlled rotations and displacements that works with a success probability of at least 25%. We also investigate the use of single bit teleportations to construct a universal set of gates on coherent state type logic and in the construction of cluster states. We finally investigate the optical Zeno gate, a gate that uses the Zeno effect in the form of two photon

  5. Investigational Approaches for Mesothelioma

    PubMed Central

    Surmont, Veerle F.; van Thiel, Eric R. E.; Vermaelen, Karim; van Meerbeeck, Jan P.

    2011-01-01

    Malignant pleural mesothelioma (MPM) is a rare, aggressive tumor with a poor prognosis. In view of the poor survival benefit from first-line chemotherapy and the lack of subsequent effective treatment options, there is a strong need for the development of more effective treatment approaches for patients with MPM. This review will provide a comprehensive state of the art of new investigational approaches for mesothelioma. In an introductory section, the etiology, epidemiology, natural history, and standard of care treatment for MPM will be discussed. This review provide an update of the major clinical trials that impact mesothelioma treatment, discuss the impact of novel therapeutics, and provide perspective on where the clinical research in mesothelioma is moving. The evidence was collected by a systematic analysis of the literature (2000–2011) using the databases Medline (National Library of Medicine, USA), Embase (Elsevier, Netherlands), Cochrane Library (Great Britain), National Guideline Clearinghouse (USA), HTA Database (International Network of Agencies for Health Technology Assessment – INAHTA), NIH database (USA), International Pleural Mesothelioma Program – WHOLIS (WHO Database), with the following keywords and filters: mesothelioma, guidelines, treatment, surgery, chemotherapy, radiotherapy, review, investigational, drugs. Currently different targeted therapies and biologicals are under investigation for MPM. It is important that the molecular biologic research should first focus on mesothelioma-specific pathways and biomarkers in order to have more effective treatment options for this disease. The use of array technology will be certainly an implicit gain in the identification of new potential prognostic or biomarkers or important pathways in the MPM pathogenesis. Probably a central mesothelioma virtual tissue bank may contribute to the ultimate goal to identify druggable targets and to develop personalized treatment for the MPM patients. PMID

  6. Microwave radar oceanographic investigations

    NASA Technical Reports Server (NTRS)

    Jackson, F. C.

    1988-01-01

    The Radar Ocean Wave Spectrometer (ROWS) technique was developed and demonstrated for measuring ocean wave directional spectra from air and space platforms. The measurement technique was well demonstrated with data collected in a number of flight experiments involving wave spectral comparisons with wave buoys and the Surface Contour Radar (SCR). Recent missions include the SIR-B underflight experiment (1984), FASINEX (1986), and LEWEX (1987). ROWS related activity is presently concentrating on using the aircraft instrument for wave-processes investigations and obtaining the necessary support (consensus) for a satellite instrument development program. Prospective platforms include EOS and the Canadian RADARSAT.

  7. VAB Sway Investigation

    NASA Technical Reports Server (NTRS)

    Youngquist, Robert c.; Ihlefeld, Curtis M.; Lane, John E.; Starr, Stanley O.

    2013-01-01

    The Vehicle Assembly Building (VAB) was constructed in the mid-1960s to house the Saturn V moon rocket while it was being assembled. Designed to withstand hurricanes and tropical storms, the V AB has a foundation consisting of 30,000 cubic yards of concrete strengthened by 4,225 steel rods driven 160 feet into limestone bedrock. The goal of the VAB Sway Investigation, which began collecting data in April 201 0 and ended in November 2012, was to quantify the displacement or sway of the VAB as a function of wind loading.

  8. Bearing fatigue investigation 3

    NASA Technical Reports Server (NTRS)

    Nahm, A. H.; Bamberger, E. N.; Signer, H. R.

    1982-01-01

    The operating characteristics of large diameter rolling-element bearings in the ultra high speed regimes expected in advanced turbine engines for high performance aircraft were investigated. A high temperature lubricant, DuPont Krytox 143 AC, was evaluated at bearing speeds to 3 million DN. Compared to the results of earlier, similar tests using a MIL-L-23699 (Type II) lubricant, bearings lubricated with the high density Krytox fluid showed significantly higher power requirements. Additionally, short bearing lives were observed when this fluid was used with AISI M50 bearings in an air atmosphere. The primary mode of failure was corrosion initiated surface distress (fatigue) on the raceways. The potential of a case-carburized bearing to sustain a combination of high-tangential and hertzian stresses without experiencing race fracture was also investigated. Limited full scale bearing tests of a 120 mm bore ball bearing at a speed of 25,000 rpm (3 million DN) indicated that a carburized material could sustain spalling fatigue without subsequent propagation to fracture. Planned life tests of the carburized material had to be aborted, however, because of apparent processing-induced material defects.

  9. SADM potentiometer anomaly investigations

    NASA Astrophysics Data System (ADS)

    Wood, Brian; Mussett, David; Cattaldo, Olivier; Rohr, Thomas

    2005-07-01

    During the last 3 years Contraves Space have been developing a Low Power (1-2kW) Solar Array Drive Mechanism (SADM) aimed at small series production. The mechanism was subjected to two test programmes in order to qualify the SADM to acceptable levels. During the two test programmes, anomalies were experienced with the Potentiometers provided by Eurofarad SA and joint investigations were undertaken to resolve why these anomalies had occurred. This paper deals with the lessons learnt from the failure investigation on the two Eurofarad (rotary) Potentiometer anomaly. The Rotary Potentiometers that were used were fully redundant; using two back to back mounted "plastic tracks". It is a pancake configuration mounted directly to the shaft of the Slip Ring Assembly at the extreme in-board end of the SADM. It has no internal bearings. The anomaly initially manifested itself as a loss of performance in terms of linearity, which was first detected during Thermal Vacuum testing. A subsequent anomaly manifested itself by the complete failure of the redundant potentiometer again during thermal vacuum testing. This paper will follow and detail the chain of events following this anomaly and identifies corrective measures to be applied to the potentiometer design and assembly process.

  10. Laboratory investigation of hypercoagulability.

    PubMed

    Francis, J L

    1998-01-01

    For many years, the laboratory investigation of patients with thrombophilia has lagged behind that of patients with bleeding diathesis. Improved understanding of the mechanisms that control and regulate coagulation, and the resultant recognition of new defects, have greatly stimulated clinical laboratory interest in this area. Assays to detect resistance to activated protein C; deficiencies of antithrombin, protein C, and protein S; and the presence of antiphospholipid antibodies are widely available and should form part of the investigation of patients that present with idiopathic thrombosis. Such a work-up will likely provide an explanation for thrombosis in 40 to 60% of patients. Abnormalities of fibrinogen and fibrinolysis may explain still more, although such defects are currently considered rare. In addition, presently unrecognized defects almost certainly exist, and the identification of such individuals will undoubtedly improve our understanding of the hemostatic mechanism. Laboratory tests to define the hypercoagulable state are continually being developed. They include whole blood coagulation and platelet function tests and novel activation markers. However, acceptance of these approaches by clinical laboratories has been slow.

  11. [MR investigations in stroke].

    PubMed

    Kenéz, József; Barsi, Péter

    2002-03-20

    In the article digital imaging methods are presented with special emphasis on the use on diagnostics of cerebral circulation studies. Recently, fundamental changes have happened in this field, concerning especially the MR investigations. These changes have influenced the therapeutic strategies of ischaemic stroke. Authors give the theoretical background on the diffusion and perfusion MR imaging, emphasising the importance of their "mismatch" and its impact in the estimation of the outcome of ischaemic events. More recently, new, controversial facts arose, regarding the reasons of the introduction of the theory of so called "negative" and "positive" mismatches. As a consequence, a level of uncertainty took place in the judgement of prognostics. The leading institutions are searching the way to solve the problem which seems to be the quantitative evaluation of the diffusion, perfusion and mismatch data. The advent of the multislice spiral CT with very fast imaging and the importance of CT investigations increased. With this new kind of equipment, even perfusion studies can be performed using iodinated contrast medium.

  12. Investigation of Surtsey Volcano

    NASA Astrophysics Data System (ADS)

    Moore, James G.; Jakobsson, Sveinn P.; Norrman, John O.

    The volcanic island of Surtsey, Iceland, was built during the period November 1963 to June 1967 and is one of the few oceanic volcanic islands that has formed and survived in recent times. New stimulus to geologic work on the island was provided in 1979 by completion of a 181-m-deep hole that was drilled to investigate the structure of the volcano and the active hydrothermal system below.During August 1985 an international group of researchers undertook a series of geologic and biologic investigations on the island. This work was facilitated by new aerial photographs taken by the Icelandic Geodetic Survey and a new bathymetric map of the Surtsy region made by the Icelandic Hydrographic Service (both in Reykjavik). Ground surveying of markers appearing in the photographs will permit a major revision of the to pographic map of the island (scale 1:5000). The new bathymetry defines the extent of continuing erosion of three volcanic vents, two of which formed short-lived islands during the Surtsey eruptive episode. Since 1967, when the first bathymetry of these submarine features was made, the summitt errace of Syrtlingur has been reduced from 23 to 32 m below sea level; that of Jolnir, from 15 to 37 m; and that of Surtla, from 32 t o 46 m.

  13. [MR investigations in stroke].

    PubMed

    Kenéz, József; Barsi, Péter

    2002-03-20

    In the article digital imaging methods are presented with special emphasis on the use on diagnostics of cerebral circulation studies. Recently, fundamental changes have happened in this field, concerning especially the MR investigations. These changes have influenced the therapeutic strategies of ischaemic stroke. Authors give the theoretical background on the diffusion and perfusion MR imaging, emphasising the importance of their "mismatch" and its impact in the estimation of the outcome of ischaemic events. More recently, new, controversial facts arose, regarding the reasons of the introduction of the theory of so called "negative" and "positive" mismatches. As a consequence, a level of uncertainty took place in the judgement of prognostics. The leading institutions are searching the way to solve the problem which seems to be the quantitative evaluation of the diffusion, perfusion and mismatch data. The advent of the multislice spiral CT with very fast imaging and the importance of CT investigations increased. With this new kind of equipment, even perfusion studies can be performed using iodinated contrast medium. PMID:12122985

  14. Laboratory investigation of hypercoagulability.

    PubMed

    Francis, J L

    1998-01-01

    For many years, the laboratory investigation of patients with thrombophilia has lagged behind that of patients with bleeding diathesis. Improved understanding of the mechanisms that control and regulate coagulation, and the resultant recognition of new defects, have greatly stimulated clinical laboratory interest in this area. Assays to detect resistance to activated protein C; deficiencies of antithrombin, protein C, and protein S; and the presence of antiphospholipid antibodies are widely available and should form part of the investigation of patients that present with idiopathic thrombosis. Such a work-up will likely provide an explanation for thrombosis in 40 to 60% of patients. Abnormalities of fibrinogen and fibrinolysis may explain still more, although such defects are currently considered rare. In addition, presently unrecognized defects almost certainly exist, and the identification of such individuals will undoubtedly improve our understanding of the hemostatic mechanism. Laboratory tests to define the hypercoagulable state are continually being developed. They include whole blood coagulation and platelet function tests and novel activation markers. However, acceptance of these approaches by clinical laboratories has been slow. PMID:9579632

  15. Magnetospheric space plasma investigations

    NASA Technical Reports Server (NTRS)

    Comfort, Richard H.; Horwitz, James L.

    1995-01-01

    Topics and investigations covering this period of this semiannual report period (August 1994 - January 1995) are as follows: (1) Generalized SemiKinetic (GSK) modeling of the synergistic interaction of transverse heating of ionospheric ions and magnetospheric plasma-driven electric potentials on the auroral plasma transport. Also, presentations of GSK modeling of auroral electron precipitation effects on ionospheric plasma outflows, of ExB effects on such outflow, and on warm plasma thermalization and other effects during refilling with pre-existing warm plasmas; (2) Referees' reports received on the statistical study of the latitudinal distributions of core plasmas along the L = 4.6 field line using DE-1/RIMS data. Other work is concerned in the same field, field-aligned flows and trapped ion distributions; and (3) A short study has been carried out on heating processes in low density flux tubes in the outer plasmasphere. The purpose was to determine whether the high ion temperatures observed in these flux tubes were due to heat sources operating through the thermal electrons or directly to the ions. Other investigations center along the same area of plasmasphere-ionosphere coupling. The empirical techniques and model, the listing of hardware calibrated, and/or tested, and a description of notable meetings attended is included in this report, along with a list of all present publication in submission or accepted and those reference papers that have resulted from this work thus far.

  16. Investigations of lunar materials

    NASA Technical Reports Server (NTRS)

    Comstock, G. M.; Fvwaraye, A. O.; Fleischer, R. L.; Hart, H. R., Jr.

    1972-01-01

    The investigations were directed at determining the radiation history and surface chronology of lunar materials using the etched particle track technique. The major lunar materials studied are the igneous rocks and double core from Apollo 12, the breccia and soil samples from Apollo 14, and the core samples from Luna 16. In the course of this work two new and potentially important observations were made: (1) Cosmic ray-induced spallation-recoil tracks were identified. The density of such tracks, when compared with the density of tracks induced by a known flux of accelerator protons, yields the time of exposure of a sample within the top meter or two of moon's surface. (2) Natural, fine scale plastic deformation was found to have fragmented pre-existing charged particle tracks, allowing the dating of the mechanical event causing the deformation.

  17. MESUR Pathfinder Science Investigations

    NASA Technical Reports Server (NTRS)

    Golombek, M.

    1993-01-01

    The MESUR (Mars Environmental Survey) Pathfinder mission is the first Discovery mission planned for launch in 1996. MESUR Pathfinder is designed as an engineering demonstration of the entry, descent and landing approach to be employed by the follow-on MESUR Network mission, which will land of order 10 small stations on the surface of Mars to investigate interior, atmospheric and surface properties. Pathfinder is a small Mars lander, equipped with a microrover to deploy instruments and explore the local landing site. Instruments selected for Pathfinder include a surface imager on a 1 m pop-up mast (stereo with spectral filters), an atmospheric structure instrument/surface meteorology package, and an alpha proton x-ray spectrometer. The microrover will carry the alpha proton x-ray spectrometer to a number of different rocks and surface materials and provide close-up imaging...

  18. Investigation of erectile dysfunction.

    PubMed

    Patel, D V; Halls, J; Patel, U

    2012-11-01

    Erectile dysfunction (ED) represents a common and debilitating condition with a wide range of organic and non-organic causes. Physical aetiologies can be divided into disorders affecting arterial inflow, the venous occlusion mechanism or the penile structure itself. Various imaging modalities can be utilised to investigate the physical causes of ED, but penile Doppler sonography (PDS) is the most informative technique, indicated in those patients with ED who do not respond to oral pharmacological agents (e.g. phosphodiesterase type 5 inhibitors). This review will examine the anatomical and physiological basis of penile erection, the method for performing PDS and features of specific causes of ED, and will also consider the alternative imaging modalities available.

  19. Vitamin D Investigation

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The solar dosimeter, a spinoff from NASA solar cell technology, measures the amount of solar radiation to which its wearer is exposed. It was used in a University of Cincinnati Medical Center investigation into the effect of sunlight exposure on maintaining vitamin D status in infants. The infants were exposed to sunlight and records were kept by mothers. Each baby wore a solar dosimeter. The two circular "eyes" in the instrument are silicon photovoltaic detectors which collect solar energy, convert it to electric signals and transmit the charge to E-cells that record the charge by plating silver ions onto an electrode. The time required to plate the silver measures the radiation received. The University found the solar dosimeter to be very effective.

  20. Investigating diffusion with technology

    NASA Astrophysics Data System (ADS)

    Miller, Jon S.; Windelborn, Augden F.

    2013-07-01

    The activities described here allow students to explore the concept of diffusion with the use of common equipment such as computers, webcams and analysis software. The procedure includes taking a series of digital pictures of a container of water with a webcam as a dye slowly diffuses. At known time points, measurements of the pixel densities (darkness) of the digital pictures are recorded and then plotted on a graph. The resulting graph of darkness versus time allows students to see the results of diffusion of the dye over time. Through modification of the basic lesson plan, students are able to investigate the influence of a variety of variables on diffusion. Furthermore, students are able to expand the boundaries of their thinking by formulating hypotheses and testing their hypotheses through experimentation. As a result, students acquire a relevant science experience through taking measurements, organizing data into tables, analysing data and drawing conclusions.

  1. Mineralogical investigations of Mars.

    PubMed

    O'Connor, J T

    1969-07-01

    A mineralogical study of Mars will offer a great deal of information on the present state of the planet and on the processes which have operated on it during the past. The degree of planetary development, the amount of igneous activity, the development of a secondary atmosphere, the presence of metamorphic or sedimentary processes, and the effects of impacting meteorites will all be recorded in the mineral assemblages. The identification of the mineral phases in the Martian rocks is the fundamental step in conducting such an investigation. Reliable phase analysis must be backed up with good elemental analyses as well, and with textural analysis of the rocks whenever possible. Many instruments including diffractometers, spectrometers, and petrographic microscopes have been designed to perform the desired analyses on unmanned spaceflights. Proper utilization of complementary techniques and a modest attention to a concerted effort on the problem will yield a quite sophisticated understanding of Mars with only a few space flights.

  2. Ship Creek bioassessment investigations

    SciTech Connect

    Cushing, C.E.; Mueller, R.P.; Murphy, M.T.

    1995-06-01

    Pacific Northwest Laboratory (PNL) was asked by Elmendorf Air Force Base (EAFB) personnel to conduct a series of collections of macroinvertebrates and sediments from Ship Creek to (1) establish baseline data on these populations for reference in evaluating possible impacts from Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) activities at two operable units, (2) compare current population indices with those found by previous investigations in Ship Creek, and (3) determine baseline levels of concentrations of any contaminants in the sediments associated with the macroinvertebrates. A specific suite of indices established by the US Environmental Protection Agency (EPA) was requested for the macroinvertebrate analyses; these follow the Rapid Bioassessment Protocol developed by Plafkin et al. (1989) and will be described. Sediment sample analyses included a Microtox bioassay and chemical analysis for contaminants of concern. These analyses included, volatile organic compounds, total gasoline and diesel hydrocarbons (EPA method 8015, CA modified), total organic carbon, and an inductive-coupled plasma/mass spectrometry (ICP/MS) metals scan. Appendix A reports on the sediment analyses. The Work Plan is attached as Appendix B.

  3. Sabatier Catalyst Poisoning Investigation

    NASA Technical Reports Server (NTRS)

    Nallette, Tim; Perry, Jay; Abney, Morgan; Knox, Jim; Goldblatt, Loel

    2013-01-01

    The Carbon Dioxide Reduction Assembly (CRA) on the International Space Station (ISS) has been operational since 2010. The CRA uses a Sabatier reactor to produce water and methane by reaction of the metabolic CO2 scrubbed from the cabin air and the hydrogen byproduct from the water electrolysis system used for metabolic oxygen generation. Incorporating the CRA into the overall air revitalization system has facilitated life support system loop closure on the ISS reducing resupply logistics and thereby enhancing longer term missions. The CRA utilizes CO2 which has been adsorbed in a 5A molecular sieve within the Carbon Dioxide Removal Assembly, CDRA. There is a potential of compounds with molecular dimensions similar to, or less than CO2 to also be adsorbed. In this fashion trace contaminants may be concentrated within the CDRA and subsequently desorbed with the CO2 to the CRA. Currently, there is no provision to remove contaminants prior to entering the Sabatier catalyst bed. The risk associated with this is potential catalyst degradation due to trace organic contaminants in the CRA carbon dioxide feed acting as catalyst poisons. To better understand this risk, United Technologies Aerospace System (UTAS) has teamed with MSFC to investigate the impact of various trace contaminants on the CRA catalyst performance at relative ISS cabin air concentrations and at about 200/400 times of ISS concentrations, representative of the potential concentrating effect of the CDRA molecular sieve. This paper summarizes our initial assessment results.

  4. Thermionic critical technology investigation

    NASA Astrophysics Data System (ADS)

    Jalichandra, P.; Hamerdinger, R. W.; Anderson, E. A.; Lamp, T. R.; Donovan, B. D.

    The thermionic critical technology investigation was initiated to enrich the technology base for thermionic space nuclear power systems. The focus of this program is on an out-of-core, Romashka type reactor system which can operate in the 5-40-kW range. The Romashka concept uses uranium carbide fuel in graphite trays which are radiatively coupled to planar thermionic converters. After completion of the design and fabrication of two state-of-the-art baseline converters, the baseline converters have been subject to further performance and life testing. To date, converter performance tests have been conducted for emitter temperatures from 1850 to 2000 K. The studies have shown that a thermionic converter with a heat-pipe-cooled collector is capable of high power conversion efficiency. By selecting the rhenium-rhenium system, in a closely spaced ignited mode converter, conversion efficiencies of 14 percent with a cell potential of 0.7 V can be readily attained. The sodium heat pipe provides a buffer against extreme changes in collector temperature due to fluctuations in converter load, one that can be improved upon by loading with an inert gas.

  5. Gear crack propagation investigations

    NASA Technical Reports Server (NTRS)

    Lewicki, David G.; Ballarini, Roberto

    1996-01-01

    Analytical and experimental studies were performed to investigate the effect of gear rim thickness on crack propagation life. The FRANC (FRacture ANalysis Code) computer program was used to simulate crack propagation. The FRANC program used principles of linear elastic fracture mechanics, finite element modeling, and a unique re-meshing scheme to determine crack tip stress distributions, estimate stress intensity factors, and model crack propagation. Various fatigue crack growth models were used to estimate crack propagation life based on the calculated stress intensity factors. Experimental tests were performed in a gear fatigue rig to validate predicted crack propagation results. Test gears were installed with special crack propagation gages in the tooth fillet region to measure bending fatigue crack growth. Good correlation between predicted and measured crack growth was achieved when the fatigue crack closure concept was introduced into the analysis. As the gear rim thickness decreased, the compressive cyclic stress in the gear tooth fillet region increased. This retarded crack growth and increased the number of crack propagation cycles to failure.

  6. Soldering In Space Investigation

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This video captures Mike Fincke melting solder during the first set of planned In-Space Soldering Investigation (ISSI) experiments onboard the International Space Station (ISS). In the video, Fincke touches the tip of the soldering iron to a wire wrapped with rosin-core solder.Review of the experiment video revealed melting kinetics, wetting characteristics, and equilibrium shape attainment of the solder charge. The main photograph shows the results of feeding solder wire onto a heated surface. Here the solder is still attached with the spool seen floating in the foreground of the image. The inset photograph at right, shows a set of three simple melting experiments in which the solder, not affected by gravity, achieved an unexpected equilibrium football shape on the wire. Samples returned to Earth were examined for porosity and flux distribution as well as micro structural development. ISSI's purpose was to find out how solder behaves in a weightless environment and promote our knowledge of fabrication and repair techniques that might be employed during extended space exploration missions.

  7. Soldering In Space Investigation

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This video captures Mike Fincke melting solder during the first set of planned In-Space Soldering Investigation (ISSI) experiments onboard the International Space Station (ISS). In the video, Fincke touches the tip of the soldering iron to a wire wrapped with rosin-core solder. Review of the experiment video revealed melting kinetics, wetting characteristics, and equilibrium shape attainment of the solder charge. The main photograph shows the results of feeding solder wire onto a heated surface. Here the solder is still attached with the spool seen floating in the foreground of the image. The inset photograph at right, shows a set of three simple melting experiments in which the solder, not affected by gravity, achieved an unexpected equilibrium football shape on the wire. Samples returned to Earth were examined for porosity and flux distribution as well as micro structural development. ISSI's purpose was to find out how solder behaves in a weightless environment and promote our knowledge of fabrication and repair techniques that might be employed during extended space exploration missions.

  8. The Dawn Topography Investigation

    NASA Technical Reports Server (NTRS)

    Raymond, C. A.; Jaumann, R.; Nathues, A.; Sierks, H.; Roatsch, T.; Preusker, E; Scholten, F.; Gaskell, R. W.; Jorda, L.; Keller, H.-U.; Zuber, M. T.; Smith, D. E.; Mastrodemos, N.; Mottola, S.

    2011-01-01

    The objective of the Dawn topography investigation is to derive the detailed shapes of 4 Vesta and 1 Ceres in order to create orthorectified image mosaics for geologic interpretation, as well as to study the asteroids' landforms, interior structure, and the processes that have modified their surfaces over geologic time. In this paper we describe our approaches for producing shape models, plans for acquiring the needed image data for Vesta, and the results of a numerical simulation of the Vesta mapping campaign that quantify the expected accuracy of our results. Multi-angle images obtained by Dawn's framing camera will be used to create topographic models with 100 m/pixel horizontal resolution and 10 m height accuracy at Vesta, and 200 m/pixel horizontal resolution and 20 m height accuracy at Ceres. Two different techniques, stereophotogrammetry and stereophotoclinometry, are employed to model the shape; these models will be merged with the asteroidal gravity fields obtained by Dawn to produce geodetically controlled topographic models for each body. The resulting digital topography models, together with the gravity data, will reveal the tectonic, volcanic and impact history of Vesta, and enable co-registration of data sets to determine Vesta's geologic history. At Ceres, the topography will likely reveal much about processes of surface modification as well as the internal structure and evolution of this dwarf planet.

  9. Radar Investigations of Asteroids

    NASA Astrophysics Data System (ADS)

    Ostro, S.

    2004-05-01

    Radar investigations have provided otherwise unavailable information about the physical and dynamical properties of about 230 asteroids. Measurements of the distribution of echo power in time delay (range) and Doppler frequency (line-of-sight velocity) provide two-dimensional images with spatial resolution as fine as a decameter. Sequences of delay-Doppler images can be used to produce geologically detailed three-dimensional models, to define the rotation state precisely, to constrain the internal density distribution, and to estimate the trajectory of the object's center of mass. Radar wavelengths (4 to 13 cm) and the observer's control of transmitted and received polarizations make the observations sensitive to near-surface bulk density and macroscopic structure. Since delay-Doppler measurements are orthogonal to optical angle measurements and typically have much finer fractional precision, they are powerful for refining orbits and prediction ephemerides. Such astrometric measurements can add decades or centuries to the interval over which an asteroid's close Earth approaches can accurately be predicted and can significantly refine collision probability estimates based on optical astrometry alone. In the highly unlikely case that a small body is on course for an Earth collision in this century, radar reconnaissance would almost immediately distinguish between an impact trajectory and a near miss and would dramatically reduce the difficulty and cost of any effort to prevent the collision. The sizes and rotation periods of radar-detected asteroids span more than four orders of magnitude. The observations have revealed both stony and metallic objects, elongated and nonconvex shapes as well as nearly featureless spheroids, small-scale morphology ranging from smoother than the lunar regolith to rougher than the rockiest terrain on Mars, craters and diverse linear structures, non-principal-axis spin states, contact binaries, and binary systems.

  10. Chemistry. Student Investigations and Readings. Investigations in Natural Science.

    ERIC Educational Resources Information Center

    Renner, John W.; And Others

    Investigations in Natural Science is a program in secondary school biology, chemistry, and physics based upon the description of science as a quest for knowledge, not the knowledge itself. This student manual contains the 19 chemistry investigations. These investigations focus on concepts related to: interactions with water; salt and calcium;…

  11. Biology. Student Investigations and Readings. Investigations in Natural Science.

    ERIC Educational Resources Information Center

    Renner, John W.; And Others

    Investigations in Natural Science is a program in secondary school biology, chemistry, and physics based upon the description of science as a quest for knowledge, not the knowledge itself. This student manual contains the 18 biology investigations. These investigations focus on concepts related to: organisms; classification; populations;…

  12. The "Civic-Minded" Professional? An Exploration through Hannah Arendt's "Vita Activa"

    ERIC Educational Resources Information Center

    Kreber, Carolin

    2016-01-01

    Recent reform initiatives calling for "civic" ("public-good" or "democratic") professionalism can be seen as a response to the widely reported decline in public trust in the professions and an attempt to partially remedy this problem through a more publically engaged professionalism. The author draws on the political…

  13. From "junk" to gene: curriculum vitae of a primate receptor isoform gene.

    PubMed

    Singer, Silke S; Männel, Daniela N; Hehlgans, Thomas; Brosius, Jürgen; Schmitz, Jürgen

    2004-08-20

    Exonization of Alu retroposons awakens public opinion, particularly when causing genetic diseases. However, often neglected, alternative "Alu-exons" also carry the potential to greatly enhance genetic diversity by increasing the transcriptome of primates chiefly via alternative splicing.Here, we report a 5' exon generated from one of the two alternative transcripts in human tumor necrosis factor receptor gene type 2 (p75TNFR) that contains an ancient Alu-SINE, which provides an alternative N-terminal protein-coding domain. We follow the primate evolution over the past 63 million years to reconstruct the key events that gave rise to a novel receptor isoform. The Alu integration and start codon formation occurred between 58 and 40 million years ago (MYA) in the common ancestor of anthropoid primates. Yet a functional gene product could not be generated until a novel splice site and an open reading frame were introduced between 40 and 25 MYA on the catarrhine lineage (Old World monkeys including apes).

  14. Human Conditions for Teaching: The Place of Pedagogy in Arendt's "Vita Activa"

    ERIC Educational Resources Information Center

    Higgins, Chris

    2010-01-01

    Background/Context: If education centrally involves self-cultivation, and the teacher's own robust selfhood is necessary for inspiring self-cultivation in students, then teacherly self-cultivation is a necessary condition of education. But teaching is seen as a helping profession, where helping others always seems, in practice if not in principle,…

  15. [From the newborn infant to the child, to the adult: historia magistra vitae].

    PubMed

    Cataldi, L; Buonsenso, D

    2008-08-01

    The hypothesis of the prenatal programming of adult diseases took on increasing interest from the moment that, in the 60s, an epidemiological association was proposed between low birth weight and cardiovascular diseases. In the last 20 years it has been demonstrated that individuals with low weight, low stature and thinness at birth have a higher risk of developing cardiovascular diseases and type 2 diabetes. Animal and clinical studies are casting light on the biological mechanisms underlying the association between modified development in the uterus and diseases, and on how growth in adolescence and in adult life can modulate this initial proneness to disease. One of the mechanisms that has aroused most interest among researchers is the reduced number of nephrons, associated with low birth weight, which predisposes to glomerulosclerosis and increased systemic arterial pressure in adult life. A correlation has also been found between low weight at birth and peripheral resistance to insulin. Nevertheless, it is thought that modified prenatal development is only a predisposing factor, open to profound influences in the course of postnatal development. It has in fact been demonstrated that accelerated development in the period of infancy and adolescence can extend the initial condition of neonatal suffering. Indirectly these studies renew and at the same time extend the concept of prevention, a priority aim of the physician of the third millennium.

  16. Educational Administration as a Historical Discipline: An "Apologia Pro Vita Historia"

    ERIC Educational Resources Information Center

    Samier, Eugenie

    2006-01-01

    This paper discusses the contributions history can make to educational administration and how history needs to be conceptualised as a humanities discipline to serve this purpose, including two aspects of the field of particular relevance to educational administration and leadership, biography and comparative studies. The value of history is…

  17. Using VITA Service Learning Experiences to Teach Hypothesis Testing and P-Value Analysis

    ERIC Educational Resources Information Center

    Drougas, Anne; Harrington, Steve

    2011-01-01

    This paper describes a hypothesis testing project designed to capture student interest and stimulate classroom interaction and communication. Using an online survey instrument, the authors collected student demographic information and data regarding university service learning experiences. Introductory statistics students performed a series of…

  18. 77 FR 6863 - Proposed Collection; Comment Request for VITA/TCE Program Forms

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ..., 8654, and 14024. DATES: Written comments should be received on or before April 9, 2012 to be assured of consideration. ADDRESSES: Direct all written comments to Yvette Lawrence, Internal Revenue Service, room 6129..., and those for whom English is a second language. Current Actions: There are no changes being made...

  19. Physics. Student Investigations and Readings. Investigations in Natural Science.

    ERIC Educational Resources Information Center

    Renner, John W.; And Others

    Investigations in Natural Science is a program in secondary school biology, chemistry, and physics based upon the description of science as a quest for knowledge, not the knowledge itself. This student manual contains the 36 physics investigations which focus on concepts related to: movement; vectors; falling objects; force and acceleration; a…

  20. Accident/Mishap Investigation System

    NASA Technical Reports Server (NTRS)

    Keller, Richard; Wolfe, Shawn; Gawdiak, Yuri; Carvalho, Robert; Panontin, Tina; Williams, James; Sturken, Ian

    2007-01-01

    InvestigationOrganizer (IO) is a Web-based collaborative information system that integrates the generic functionality of a database, a document repository, a semantic hypermedia browser, and a rule-based inference system with specialized modeling and visualization functionality to support accident/mishap investigation teams. This accessible, online structure is designed to support investigators by allowing them to make explicit, shared, and meaningful links among evidence, causal models, findings, and recommendations.

  1. A Psychoacoustic Investigation of Foreignness.

    ERIC Educational Resources Information Center

    Alford, Bronwyn Lindsay

    A study was conducted to investigate and measure the foreignness of ten languages. Forty-five listeners judged the relative foreignness of 2,250 paired utterances, and ordinal scales were made from their judgments. The purpose of the investigation was to determine the feasibility of the development of an auditory, foreign-language aptitude test…

  2. ENGINEERING CONSIDERATIONS: WATERBORNE DISEASE INVESTIGATIONS

    EPA Science Inventory

    As part of a disease outbreak investigation involving drinking water, an engineering investigation may be necessary to determine how or why the pathogen of concern was able to get to the consumer. In many of the US outbreaks, the survival of the pathogen was dependent on multiple...

  3. Geophysical investigations at Momotombo, Nicaragua

    SciTech Connect

    Cordon, U.J.; Zurflueh, E.G.

    1980-09-01

    The Momotombo geothermal field in Nicaragua was investigated in three exploration stages, using a number of geophysical techniques. Stage 1 of the investigations by Texas Instruments, Inc., (1970) located and delineated a potential geothermal field, with the dipole mapping surveys and electromagnetic soundings being most effective. Stage 2 of the investigations, performed in 1973 by the United Nations Development Program (UNDP), outlined the resistivity anomalies in the area west of the previously selected field; Schlumberger VES soundings and constant depth profiling (SCDP) proved most useful. During Stage 3 of the investigations, Electroconsult (ELC) performed 20 additional Schlumberger VES soundings as part of the 1975 plant feasibility studies. Results of these geophysical techniques are summarized and their effectiveness briefly discussed.

  4. Financial Crisis Criminal Investigation Act

    THOMAS, 113th Congress

    Rep. Kaptur, Marcy [D-OH-9

    2013-01-03

    01/25/2013 Referred to the Subcommittee on Crime, Terrorism, Homeland Security, And Investigations. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  5. COFS 1 Guest Investigator Program

    NASA Technical Reports Server (NTRS)

    Fontana, Anthony; Wright, Robert L.

    1986-01-01

    The process for selecting guest investigators for participation in the Control of Flexible Structures (COFS)-1 program is described. Contracts and grants will be awarded in late CY87. A straw-man list of types of experiments and a distribution of the experiments has been defined to initiate definition of an experiments package which supports development and validation of control structures interaction technology. A schedule of guest investigator participation has been developed.

  6. Los Alamos Laser Eye Investigation.

    SciTech Connect

    Odom, C. R.

    2005-01-01

    A student working in a laser laboratory at Los Alamos National Laboratory sustained a serious retinal injury to her left eye when she attempted to view suspended particles in a partially evacuated target chamber. The principle investigator was using the white light from the flash lamp of a Class 4 Nd:YAG laser to illuminate the particles. Since the Q-switch was thought to be disabled at the time of the accident, the principal investigator assumed it would be safe to view the particles without wearing laser eye protection. The Laboratory Director appointed a team to investigate the accident and to report back to him the events and conditions leading up to the accident, equipment malfunctions, safety management causal factors, supervisory and management action/inaction, adequacy of institutional processes and procedures, emergency and notification response, effectiveness of corrective actions and lessons learned from previous similar events, and recommendations for human and institutional safety improvements. The team interviewed personnel, reviewed documents, and characterized systems and conditions in the laser laboratory during an intense six week investigation. The team determined that the direct and primary failures leading to this accident were, respectively, the principle investigator's unsafe work practices and the institution's inadequate monitoring of worker performance. This paper describes the details of the investigation, the human and institutional failures, and the recommendations for improving the laser safety program.

  7. Cognitive fallacies and criminal investigations.

    PubMed

    Ditrich, Hans

    2015-03-01

    The human mind is susceptible to inherent fallacies that often hamper fully rational action. Many such misconceptions have an evolutionary background and are thus difficult to avert. Deficits in the reliability of eye-witnesses are well known to legal professionals; however, less attention has been paid to such effects in crime investigators. In order to obtain an "inside view" on the role of cognitive misconceptions in criminalistic work, a list of fallacies from the literature was adapted to criminalistic settings. The statements on this list were rated by highly experienced crime scene investigators according to the assumed likelihood of these errors to appear and their severity of effect. Among others, selective perception, expectation and confirmation bias, anchoring/"pars per toto" errors and "onus probandi"--shifting the burden of proof from the investigator to the suspect--were frequently considered to negatively affect criminal investigations. As a consequence, the following measures are proposed: alerting investigating officers in their training to cognitive fallacies and promoting the exchange of experiences in peer circles of investigators on a regular basis. Furthermore, the improvement of the organizational error culture and the establishment of a failure analysis system in order to identify and alleviate error prone processes are suggested. PMID:25754002

  8. Hurricane Katrina Wind Investigation Report

    SciTech Connect

    Desjarlais, A. O.

    2007-08-15

    This investigation of roof damage caused by Hurricane Katrina is a joint effort of the Roofing Industry Committee on Weather Issues, Inc. (RICOWI) and the Oak Ridge National Laboratory/U.S. Department of Energy (ORNL/DOE). The Wind Investigation Program (WIP) was initiated in 1996. Hurricane damage that met the criteria of a major windstorm event did not materialize until Hurricanes Charley and Ivan occurred in August 2004. Hurricane Katrina presented a third opportunity for a wind damage investigation in August 29, 2005. The major objectives of the WIP are as follows: (1) to investigate the field performance of roofing assemblies after major wind events; (2) to factually describe roofing assembly performance and modes of failure; and (3) to formally report results of the investigations and damage modes for substantial wind speeds The goal of the WIP is to perform unbiased, detailed investigations by credible personnel from the roofing industry, the insurance industry, and academia. Data from these investigations will, it is hoped, lead to overall improvement in roofing products, systems, roofing application, and durability and a reduction in losses, which may lead to lower overall costs to the public. This report documents the results of an extensive and well-planned investigative effort. The following program changes were implemented as a result of the lessons learned during the Hurricane Charley and Ivan investigations: (1) A logistics team was deployed to damage areas immediately following landfall; (2) Aerial surveillance--imperative to target wind damage areas--was conducted; (3) Investigation teams were in place within 8 days; (4) Teams collected more detailed data; and (5) Teams took improved photographs and completed more detailed photo logs. Participating associations reviewed the results and lessons learned from the previous investigations and many have taken the following actions: (1) Moved forward with recommendations for new installation procedures

  9. Ground water investigations in Oklahoma

    USGS Publications Warehouse

    Davis, Leon V.

    1955-01-01

    Prior to 1937, ground-water work in Oklahoma consisted of broad scale early-day reconnaissance and a few brief investigations of local areas. The reconnaissance is distinguished by C. N. Gould's "Geology and Water Resources of Oklahoma" (Water-Supply Paper 148, 1905), which covers about half of the present State of Oklahoma. Among the shorter reports are two by Schwennesen for areas near Enid and Oklahoma City, one by Renick for Enid, and one by Thompson on irrigation possibilities near Gage. These reports are now inadequate by modern standards. Cooperative ground-water work in Oklahoma by the United States Geological Survey began in 1937, with the Oklahoma Geological Survey as cooperating agency. With the passage of the new ground-water law by the State Legislature in 1949, the need for more information on available ground waters and the safe yield of the various aquifers became very pressing. Accordingly, the Division of Water Resources of the Oklahoma Planning and Resources Board, to which was delegated the responsibility of administering the Ground-Water Law, entered into a cooperative agreement with the U.S. Geological Survey, providing for an expansion of ground-water investigations. Both cooperators have consistently given full and enthusiastic cooperation, often beyond the requirements of the cooperative program. The first cooperative investigation was an evaluation of ground-water supplies available for irrigation in the Panhandle. In 1937 the Panhandle was still very much in the dust bowl, and it was hoped that irrigation would alleviate the drought. A bulletin on Texas County was published in 1939, and one on Cimarron County in 1943. Ground-water investigations during the World War II were restricted to the demands of Army and Navy installations, and to defense industries. Ground-water investigations since 1945 have included both country-wide and aquifer-type investigations. In Oklahoma it has been the policy for the State cooperator to publish the

  10. Responsibility-Based Youth Programs Evaluation: Investigating the Investigations.

    ERIC Educational Resources Information Center

    Hellison, Don; Walsh, David

    2002-01-01

    Reviews 26 studies that have investigated the impact of the personal-social responsibility model (RM), a physical activity program model, on underserved and/or at-risk youth since its inception. Results indicate that field research encompasses a wide range of approaches. However, the 26 studies enhance the theoretical and practical potential of RM…

  11. 100 Areas CERCLA ecological investigations

    SciTech Connect

    Landeen, D.S.; Sackschewsky, M.R.; Weiss, S.

    1993-09-01

    This document reports the results of the field terrestrial ecological investigations conducted by Westinghouse Hanford Company during fiscal years 1991 and 1992 at operable units 100-FR-3, 100-HR-3, 100-NR-2, 100-KR-4, and 100-BC-5. The tasks reported here are part of the Remedial Investigations conducted in support of the Comprehensive Environmental Response, compensation, and Liability Act of 1980 studies for the 100 Areas. These ecological investigations provide (1) a description of the flora and fauna associated with the 100 Areas operable units, emphasizing potential pathways for contaminants and species that have been given special status under existing state and/or federal laws, and (2) an evaluation of existing concentrations of heavy metals and radionuclides in biota associated with the 100 Areas operable units.

  12. Critical Viscosity of Xenon investigators

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Dr. Dr. Robert F. Berg (right), principal investigator and Dr. Micheal R. Moldover (left), co-investigator, for the Critical Viscosity of Xenon (CVX/CVX-2) experiment. They are with the National Institutes of Standards and Technology, Gaithersburg, MD. The Critical Viscosity of Xenon Experiment (CVX-2) on the STS-107 Research 1 mission in 2002 will measure the viscous behavior of xenon, a heavy inert gas used in flash lamps and ion rocket engines, at its critical point. Although it does not easily combine with other chemicals, its viscosity at the critical point can be used as a model for a range of chemicals.

  13. Investigation of the Challenger Accident

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The work of the Presidential Commission on the Space Shuttle Challenger Accident (hereafter referred to as the Rogers Commission) and the work of the National Aeronautics and Space Administration in investigating the causes of the accident were reviewed. In addition to reviewing the five volumes of the Rogers Commission, the entire direct on-line Rogers Commission data base, which included full-text and document retrieval capability was also reviewed. The findings and recommendations contained also include materials submitted for the record, staff investigations, interviews, and trips.

  14. Investigation of Livingstone's curious point.

    PubMed

    Martin, Vaughan

    2007-12-01

    The explorer and missionary David Livingstone was identified after death by the appearances of his humerus which had been damaged in an encounter with a lion. In his writings Livingstone suggested that the consequences of the lion's attack were not as bad as he might have expected. He wondered if this was due to the fact that he was wearing a tartan jacket when he was attacked and suggested that this curious point should be investigated. This paper looks at some of the dyes used in tartans of the time and investigates their effect on the bacteria that might be present in the mouths of lions.

  15. Investigating University-School Partnerships

    ERIC Educational Resources Information Center

    Nath, Janice, Ed.; Guadarrama, Irma N., Ed.; Ramsey, John, Ed.

    2011-01-01

    Investigating University-School Partnerships: A Volume in Professional Development School Research, the fourth book in the PDS Research Series developed by the same editors, includes a collection of organized papers that represent the best and latest examples of practitioner thinking, research, and program design and evaluation in the field at the…

  16. Investigating Gender Differences in Reading

    ERIC Educational Resources Information Center

    Logan, Sarah; Johnston, Rhona

    2010-01-01

    Girls consistently outperform boys on tests of reading comprehension, although the reason for this is not clear. In this review, differences between boys and girls in areas relating to reading will be investigated as possible explanations for consistent gender differences in reading attainment. The review will examine gender differences within the…

  17. Visualizing Chemistry: Investigations for Teachers.

    ERIC Educational Resources Information Center

    Ealy, Julie B.; Ealy, James L., Jr.

    This book contains 101 investigations for chemistry classrooms. Topics include: (1) Physical Properties; (2) Reactions of Some Elements; (3) Reactions Involving Gases; (4) Energy Changes; (5) Solutions and Solubility; (6) Transition Metals and Complex Ions; (7) Kinetics and Equilibrium; (8) Acids and Bases; (9) Oxidation-Reduction; (10)…

  18. Police close unsolved 'climategate' investigation

    NASA Astrophysics Data System (ADS)

    Lavender, Gemma

    2012-09-01

    Police in Norfolk in the UK have closed an investigation into the hacking of e-mails at the University of East Anglia's Climate Research Unit (CRU) after admitting that they will not be able to find the hackers who broke into CRU computer servers.

  19. Campus Life and Government Investigations.

    ERIC Educational Resources Information Center

    Shekleton, James F.

    This paper discusses the proper way to conduct official government investigations on college campuses within the framework of the Fourth Amendment to the United States Constitution which protects against unreasonable searches and seizures. The article emphasizes that this amendment lays the groundwork for the limitations on the exercise of…

  20. An Investigation of Milk Sugar.

    ERIC Educational Resources Information Center

    Smith, Christopher A.; Dawson, Maureen M.

    1987-01-01

    Describes an experiment to identify lactose and estimate the concentration of lactose in a sample of milk. Gives a background of the investigation. Details the experimental method, results and calculations. Discusses the implications of the experiment to students. Suggests further experiments using the same technique used in "miniprojects." (CW)

  1. Indoor air quality investigation protocols

    SciTech Connect

    Greene, R.E.; Williams, P.L.

    1996-10-01

    Over the past 10 to 15 years, an increasing number of complaints about discomfort and health effects related to indoor air quality (IAQ) have been reported. The increase in complaints has been accompanied by an increase in requests for IAQ investigations. This study presents an overview of the many IAQ investigation protocols published since 1984. For analysis, the protocols are divided into four categories: solution-oriented, building diagnostics, industrial hygiene, and epidemiology. In general, the protocols begin with general observations, proceed to collect more specific data as indicated, and end with conclusions and recommendations. A generic IAQ protocol is presented that incorporates the common aspects of the various protocols. All of the current protocols place heavy emphasis on the ventilation system during the investigation. A major problem affecting all of the current protocols is the lack of generally accepted IAQ standards. IN addition, the use of questionnaires, occupant interviews, and personal diaries (as well as the point in the investigation at which they are administered) differs among the protocols. Medical evaluations and verification procedures also differ among the protocols.

  2. Mobilising Ethnographers Investigating Technologised Learning

    ERIC Educational Resources Information Center

    Landri, Paolo

    2013-01-01

    This paper intends to problematise understandings of the ethnographer's presence in investigating contemporary forms of technologised learning. The ubiquity of new educational technologies raises questions concerning the spaces of education and learning, and challenges, at the same time, the sense of "being there" in terms of the face-to-face…

  3. Investigating Evolution with Living Plants.

    ERIC Educational Resources Information Center

    Schlessman, Mark A.

    1997-01-01

    Describes two investigative labs that use live plants to illustrate important biological principles, include quantitative analysis, and require very little equipment. Each lab is adaptable to a variety of class sizes, course contents, and student backgrounds. Topics include the evolution of flower size in Mimulus and pollination of Brassicas. (DDR)

  4. An investigation of empennage buffeting

    NASA Technical Reports Server (NTRS)

    Lan, C. E.; Lee, I. G.

    1986-01-01

    Progress in the investigation of empennage buffeting in reviewed. In summary, the following tasks were accomplished: relevant literatures was reviewed; equations for calculating structural response were formulated; root-mean-square values of root bending moment for a 65-degree rigid delta wing were calculated and compared with data; and a water-tunnel test program for an F-18 model was completed.

  5. How to investigate multisystem disease.

    PubMed

    Watts, Richard A

    2014-12-01

    The investigation of the patient with possible systemic autoimmune rheumatic disease is potentially one of the most challenging areas of rheumatology as the differential diagnosis is potentially very broad. The investigative approach should not only be directed at confirming the diagnosis of an autoimmune rheumatic disease but also at excluding as best as possible the major alternative diagnoses of malignancy and infection. A systematic approach should yield a positive diagnosis in the majority of cases based on excluding infection by appropriate cultures and serology, malignancy using imaging including 18-fluorodeoxyglucose positron emission tomography/computerized tomography (FDG PET/CT). The most important part of the assessment is the history, in particular covering systems that may not previously been assessed such as ears, nose, throat or eyes. The clue to the diagnosis of an autoimmune rheumatic disease often lies in detecting the multisystem nature of the condition and the cumulative effects of multiorgan involvement. Investigation may therefore need to cover different systems. Although stratified approaches have been described, they have not been subjected to a detailed investigation as to their effectiveness. PMID:26096088

  6. 78 FR 64026 - Investigative Hearing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... factual information for the ongoing investigation into two Metro-North Railroad accidents that occurred in... passengers on each train at the time of the accident. Metro-North estimated damage at $18.5 million. On..., Subdivision 7, in West Haven, CT. The accident occurred at milepost 69.58 on main track 1. The track...

  7. Matriculation Outcomes: A Regional Investigation.

    ERIC Educational Resources Information Center

    Martinez, Daniel

    This document, originally published in a journal, investigates whether matriculation works and if so how does it affect students. The document uses the data from a study done at the Riverside Community College District (RCCD), which addressed the effect of matriculation on student persistence. The RCCD data came from a variety of sources and…

  8. Investigating Minerals: Promoting Integrated Inquiry

    ERIC Educational Resources Information Center

    Thompson, Rudi; Carmack, Elizabeth

    2007-01-01

    "Mineral Detectives!" is one of eighteen lessons in the "Private Whys?" integrated science unit, which uses a guided inquiry investigation to teach students in grades three through five about the role of minerals in our lives. The University of North Texas developed "Private Whys?" with funding from the Copper Development Association. This lesson…

  9. IMPROVING WATERBORNE DISEASE OUTBREAK INVESTIGATIONS

    EPA Science Inventory

    This article summarizes the discussions and conclusions of a workshop held December 7-8, 1998, to consider the inherent limitations and weaknesses of waterborne outbreak investigations and make recommendations for their improvement. In recent years, an increased number of suspec...

  10. The Glast Guest Investigator Program

    SciTech Connect

    Band, David L.

    2007-07-12

    We provide an overview of the GLAST Guest Investigator (GI) program, which will support basic research relevant to the GLAST mission in yearly cycles beginning approximately two months after launch. Current details about the GLAST GI program will always be posted on the GLAST Science Support Center (GSSC) website: http://glast.gsfc.nasa.gov/ssc/.

  11. Investigations on Multiplication of Fractions.

    ERIC Educational Resources Information Center

    Sai, Khoo Phon; Inder, Walter R. D.

    1984-01-01

    Three different models with continuous materials, discontinuous materials, and number lines were used to study the operation concept in six investigations on multiplication with fractions with pupils aged 11-12 in a Penang International School. All approaches could be understood by pupils, but they preferred the area and fractional models. (MNS)

  12. Scientific Investigation with the SJCSI

    NASA Astrophysics Data System (ADS)

    Berbey, E.; Delpeyroux, G.; Douay, E.; Juchereau, C.; Garavet, O.

    2012-04-01

    Scientific Investigation with the SJCSI (Saint Jean* Crime Scene Investigation) Our work, which we have been teaching for 3 years, consists of a scientific investigation. We create a case from A to Z and then our students (15 to 16 years old) are meant to collect samples and clues from a reconstituted crime scene and then have to catch the culprit thanks to laboratory tests crossing four subjects: Physics and Chemistry, Biology, Math and English. I'm a biology teacher and I work with 3 other teachers in my school. The objectives of these activities are: • Make sciences more attractive by putting them into a context of crime investigation. • Use science techniques to find a culprit or to clear a suspect. • To acquire scientific knowledge. • Realize that the different scientific subjects complement each other to carry out a survey. • Use English language and improve it. The investigation consists of doing experiments after collecting different samples and clues on the crime scene. Examples of Biology experimentation: • Detecting the origin of the blood samples found on the crime scene. Students observe blood samples with a microscope and compare the characteristics to those of human blood found on the web. They discover that blood samples found aren't human blood because the red cells have a nucleus. By using the information given in the scenario, they discover that blood sample belongs to the parrot of a suspect. Students, also take a photo of their microscopic preparations, add title and caption and so they learn the cell's structure and the characteristics of blood cells. • In another case, students have to study the blood sample found under the victims fingernails. They observe blood preparation and compare it to the blood of a suspect who has a genetic disease: drepanocytosis. So, they discover the characteristics of blood cells by comparing them to sickle cells. • DNA electrophoresis to identify DNA found, for example, on the gun. • Blood type

  13. ATMOS Spacelab 1 science investigation

    NASA Technical Reports Server (NTRS)

    Park, J. H.; Smith, M. A. H.; Twitty, J. T.; Russell, J. M., III

    1979-01-01

    Existing infrared spectra from high speed interferometer balloon flights were analyzed and experimental analysis techniques applicable to similar data from the ATMOS experiment (Spacelab 3) were investigated. Specific techniques under investigation included line-by-line simulation of the spectra to aid in the identification of absorbing gases, simultaneous retrieval of pressure and temperature profiles using carefully chosen pairs of CO2 absorption lines, and the use of these pressures and temperatures in the retrieval of gas concentration profiles for many absorbing species. A search for a new absorption features was also carried out, and special attention was given to identification of absorbing gases in spectral bandpass regions to be measured by the halogen occultation experiment.

  14. Incident reporting: the bureau investigation.

    PubMed

    Mains, Paul

    2015-01-01

    The Bureau Investigation (BI) is a type of report that lends itself to the internal complaints often generated within a bureaucracy, the author reports, and ranges from discourtesy complaints on a single shift or a single officer to the more complex, sensitive inquiries called for by the senior administration. In this article he explores the many facets of the BI which must be mastered. PMID:26647506

  15. The Ontology for Biomedical Investigations.

    PubMed

    Bandrowski, Anita; Brinkman, Ryan; Brochhausen, Mathias; Brush, Matthew H; Bug, Bill; Chibucos, Marcus C; Clancy, Kevin; Courtot, Mélanie; Derom, Dirk; Dumontier, Michel; Fan, Liju; Fostel, Jennifer; Fragoso, Gilberto; Gibson, Frank; Gonzalez-Beltran, Alejandra; Haendel, Melissa A; He, Yongqun; Heiskanen, Mervi; Hernandez-Boussard, Tina; Jensen, Mark; Lin, Yu; Lister, Allyson L; Lord, Phillip; Malone, James; Manduchi, Elisabetta; McGee, Monnie; Morrison, Norman; Overton, James A; Parkinson, Helen; Peters, Bjoern; Rocca-Serra, Philippe; Ruttenberg, Alan; Sansone, Susanna-Assunta; Scheuermann, Richard H; Schober, Daniel; Smith, Barry; Soldatova, Larisa N; Stoeckert, Christian J; Taylor, Chris F; Torniai, Carlo; Turner, Jessica A; Vita, Randi; Whetzel, Patricia L; Zheng, Jie

    2016-01-01

    The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource (http://obi-ontology.org) providing details on the people, policies, and issues being addressed

  16. Shuttle Fuel Feedliner Cracking Investigation

    NASA Technical Reports Server (NTRS)

    Nesman, Tomas E.; Turner, Jim (Technical Monitor)

    2002-01-01

    This presentation provides an overview of material covered during 'Space Shuttle Fuel Feedliner Cracking Investigation MSFC Fluids Workshop' held November 19-21, 2002. Topics covered include: cracks on fuel feed lines of Orbiter space shuttles, fluid driven cracking analysis, liner structural modes, structural motion in a fluid, fluid borne drivers, three dimensional computational fluid dynamics models, fluid borne drivers from pumps, amplification mechanisms, flow parameter mapping, and flight engine flow map.

  17. Investigation of dynamic ground effect

    NASA Technical Reports Server (NTRS)

    Chang, Ray Chung; Muirhead, Vincent U.

    1987-01-01

    An experimental investigation of dynamic ground effect was conducted in the Univ. of Kansas wind tunnel using delta wings of 60, 70, 75 deg sweep; the XB-70 wing; and the F-104A wing. Both static and dynamic tests were made. Test data were compared to other test data, including dynamic flight test data of the XB-70 and F-104A. Limited flow visualization test were conducted. A significant dynamic effect was found for highly swept delta wings.

  18. Transient Wave Rotor Performance Investigated

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The NASA Lewis Research Center is investigating the wave rotor for use as a core gas generator in future gas turbine engines. The device, which uses gas-dynamic waves to transfer energy directly to and from the working fluid through which the waves travel, consists of a series of constant-area passages that rotate about an axis. Through rotation, the ends of the passages are periodically exposed to various circumferentially arranged ports that initiate the traveling waves within the passages.

  19. The Ontology for Biomedical Investigations

    PubMed Central

    Bandrowski, Anita; Brinkman, Ryan; Brochhausen, Mathias; Brush, Matthew H.; Chibucos, Marcus C.; Clancy, Kevin; Courtot, Mélanie; Derom, Dirk; Dumontier, Michel; Fan, Liju; Fostel, Jennifer; Fragoso, Gilberto; Gibson, Frank; Gonzalez-Beltran, Alejandra; Haendel, Melissa A.; He, Yongqun; Heiskanen, Mervi; Hernandez-Boussard, Tina; Jensen, Mark; Lin, Yu; Lister, Allyson L.; Lord, Phillip; Malone, James; Manduchi, Elisabetta; McGee, Monnie; Morrison, Norman; Overton, James A.; Parkinson, Helen; Peters, Bjoern; Rocca-Serra, Philippe; Ruttenberg, Alan; Sansone, Susanna-Assunta; Scheuermann, Richard H.; Schober, Daniel; Smith, Barry; Soldatova, Larisa N.; Stoeckert, Christian J.; Taylor, Chris F.; Torniai, Carlo; Turner, Jessica A.; Vita, Randi; Whetzel, Patricia L.; Zheng, Jie

    2016-01-01

    The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource (http://obi-ontology.org) providing details on the people, policies, and issues being addressed

  20. The Ontology for Biomedical Investigations.

    PubMed

    Bandrowski, Anita; Brinkman, Ryan; Brochhausen, Mathias; Brush, Matthew H; Bug, Bill; Chibucos, Marcus C; Clancy, Kevin; Courtot, Mélanie; Derom, Dirk; Dumontier, Michel; Fan, Liju; Fostel, Jennifer; Fragoso, Gilberto; Gibson, Frank; Gonzalez-Beltran, Alejandra; Haendel, Melissa A; He, Yongqun; Heiskanen, Mervi; Hernandez-Boussard, Tina; Jensen, Mark; Lin, Yu; Lister, Allyson L; Lord, Phillip; Malone, James; Manduchi, Elisabetta; McGee, Monnie; Morrison, Norman; Overton, James A; Parkinson, Helen; Peters, Bjoern; Rocca-Serra, Philippe; Ruttenberg, Alan; Sansone, Susanna-Assunta; Scheuermann, Richard H; Schober, Daniel; Smith, Barry; Soldatova, Larisa N; Stoeckert, Christian J; Taylor, Chris F; Torniai, Carlo; Turner, Jessica A; Vita, Randi; Whetzel, Patricia L; Zheng, Jie

    2016-01-01

    The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource (http://obi-ontology.org) providing details on the people, policies, and issues being addressed

  1. Systems special investigation group overview

    NASA Technical Reports Server (NTRS)

    Mason, James B.; Dursch, Harry; Edelman, Joel

    1992-01-01

    The Systems Special Investigation Group (SIG) has undertaken investigations in the four major engineering disciplines represented by LDEF hardware: electrical, mechanical, thermal, and optical systems. Testing was planned for the highest possible level of assembly, and top level system tests for nearly all systems were performed at this time. Testing to date was performed on a mix of LDEF and individual experimenter systems. No electrical or mechanical system level failures attributed to the spaceflight environment were detected by the Systems SIG. Some low cost electrical components were used successfully, although relays were a continuing problem. Extensive mechanical galling was observed, but no evidence of coldwelding was identified. A working index of observed systems anomalies was created and will be used to support the tracking and resolution of these effects. LDEF hardware currently available to the Systems SIG includes most of the LDEF facility systems hardware, and some significant experimenter hardware as well. A series of work packages was developed for each of several subsystem types where further testing is of critical interest. The Systems SIG is distributing a regular newsletter to the greater LDEF community in order to maintain coherence in an investigation which is widely scattered both in subject matter and in geography. Circulation of this informal document has quadrupled in its first year.

  2. Systems special investigation group overview

    NASA Technical Reports Server (NTRS)

    Mason, James B.; Dursch, Harry; Edelman, Joel

    1991-01-01

    The Systems Special Investigation Group (SIG) has undertaken investigations in the four major engineering disciplines represented in the Long Duration Exposure Facility (LDEF) hardware: electrical, mechanical, thermal, and optical systems. Testing was planned for the highest possible level of assembly, and top level system tests for nearly all systems were performed at this time. To date, testing was performed on a mix of LDEF and individual experimenter systems. No electrical or mechanical system level failures attributed to the spaceflight environment have yet been detected. Some low cost electrical components were used successfully, although relays were a continuing problem. Mechanical galling was observed unexpectedly, but no evidence of cold welding was identified yet. A working index of observed systems anomalies was created and will be used to support the tracking and resolution of these effects. The LDEF hardware currently available to the Systems SIG includes most of the LDEF systems hardware, and some significant experimenter hardware as well. A series of work packages was developed for each of several subsystem types where further testing is of critical interest. The System SIG is distributing a regular newsletter to the greater LDEF community in order to maintain coherence in an investigation which is widely scattered both in subject matter and in geography. Circulation of this informal document has quadrupled in its first year.

  3. Investigational Drugs for Visceral Leishmaniasis

    PubMed Central

    Sundar, Shyam; Chakravarty, Jaya

    2014-01-01

    Introduction The armamentarium of antileishmanials is small. It is further being threatened by development of resistance and decreasing sensitivity to the available drugs. Development of newer drugs are sorely needed. Areas covered Literature search on investigational drugs for visceral leishmaniasis (VL) was done on PubMed. Those candidates with at least in vitro and in vivo activity against leishmania species causing VL were reviewed. Among the investigational drugs the nitroimidazole compound fexinidazole is the one of the few drugs which has reached phase II trials. Although the (S)-PA-824 is in phase II trials for the treatment of tuberculosis its R enantiomer has shown good antileishmanial activity. Development of sitamaquin, which has completed phase II studies has been stopped for VL due to its low efficacy. Many novel delivery system and oral formulations of Amphotericin B which are cheap and less toxic are in investigational stages, and will go a long way in improving the treatment of VL. Expert opinion Very few new drugs have reached the clinical stage in the treatment of this neglected tropical disease. Thus, there is an urgent need for support from public private partnerships to ensure that drug candidates are promptly taken forward into development. PMID:25409760

  4. Stress concentration investigations using NASTRAN

    NASA Technical Reports Server (NTRS)

    Gillcrist, M. C.; Parnell, L. A.

    1986-01-01

    Parametic investigations are performed using several two dimensional finite element formulations to determine their suitability for use in predicting extremum stresses in marine propellers. Comparisons are made of two NASTRAN elements (CTRIM6 and CTRAIA2) wherein elasticity properties have been modified to yield plane strain results. The accuracy of the elements is investigated by comparing finite element stress predictions with experimentally determined stresses in two classical cases: (1) tension in a flat plate with a circular hole; and (2) a filleted flat bar subjected to in-plane bending. The CTRIA2 element is found to provide good results. The displacement field from a three dimensional finite element model of a representative marine propeller is used as the boundary condition for the two dimensional plane strain investigations of stresses in the propeller blade and fillet. Stress predictions from the three dimensional analysis are compared with those from the two dimensional models. The validity of the plane strain modifications to the NASTRAN element is checked by comparing the modified CTRIA2 element stress predictions with those of the ABAQUS plane strain element, CPE4.

  5. Supernumerary Teeth: An Investigating Tool in Forensic Crime Investigation

    PubMed Central

    Multani, Rupinder Kaur; Sangeri, Kishore Kumar; Ramalakshmi, M; Pavithra, S; Rajesh, M; Singh, Laiphrakpam Girindra

    2015-01-01

    Background: Supernumerary tooth is an additional entity to the normal series and is seen in all the quadrants of the jaw. The prevalence rates of supernumerary teeth in the permanent dentition, reported in the literature, vary between 0.1% and 6.9%. The presence of supernumerary teeth may be part of developmental disorders. As supernumerary tooth is a rare condition, it can be used as identification tool for crime investigation. Material and Methods: A total of 30 volunteers with a supernumerary tooth were analyzed and casts were made after taking alginate impression. All the casts were coded and were given to five observers for correct identification of those volunteers with respective prepared cast. Result: Personal identification and the cast identification of volunteers were done (cast of the volunteers). The matching identification is followed as below: Of five observers 1st observer able to detect 25 (83%), 2nd observer 27 (90%), 3rd observer 26 (87%), 4th observer 25 (83%) and 5th observer 28 (91%). Conclusion: As positive matching identification was 87%, supernumerary tooth can be used for crime investigation and used as greatest weapon in criminal identification. PMID:26028905

  6. Rosetta Radio Science Investigations (RSI)

    NASA Astrophysics Data System (ADS)

    Pätzold, Martin; Häusler, Bernd; Aksnes, Kaare; Anderson, John D.; Asmar, Sami W.; Barriot, Jean-Pierre; Bird, Michael K.; Boehnhardt, Hermann; Eidel, Werner; Grün, Eberhardt; Ip, Wing H.; Marouf, Essam; Morley, Trevor; Neubauer, Fritz M.; Rickman, Hans; Thomas, Nicolas; Tsurutani, Bruce T.; Wallis, Max K.; Wickramasinghe, N. C.; Mysen, Eirik; Olson, Oystein; Remus, Stefan; Tellmann, Silvia; Andert, Thomas; Carone, Ludmila; Fels, Markus; Stanzel, Christina; Audenrieth-Kersten, Iris; Gahr, Alexander; Müller, Anna-Liane; Stupar, Dusan; Walter, Christina

    2007-02-01

    The Rosetta spacecraft has been successfully launched on 2nd March 2004 to its new target comet 67 P/Churyumov-Gerasimenko. The science objectives of the Rosetta Radio Science Investigations (RSI) experiment address fundamental aspects of cometary physics such as the mass and bulk density of the nucleus, its gravity field, its interplanetary orbit perturbed by nongravitational forces, its size and shape, its internal structure, the composition and roughness of the nucleus surface, the abundance of large dust grains, the plasma content in the coma and the combined dust and gas mass flux. The masses of two asteroids, Steins and Lutetia, shall be determined during flybys in 2008 and 2010, respectively. Secondary objectives are the radio sounding of the solar corona during the superior conjunctions of the spacecraft with the Sun during the cruise phase. The radio carrier links of the spacecraft Telemetry, Tracking and Command (TT&C) subsystem between the orbiter and the Earth will be used for these investigations. An Ultrastable oscillator (USO) connected to both transponders of the radio subsystem serves as a stable frequency reference source for both radio downlinks at X-band (8.4 GHz) and S-band (2.3 GHz) in the one-way mode. The simultaneous and coherent dual-frequency downlinks via the High Gain Antenna (HGA) permit separation of contributions from the classical Doppler shift and the dispersive media effects caused by the motion of the spacecraft with respect to the Earth and the propagation of the signals through the dispersive media, respectively. The investigation relies on the observation of the phase, amplitude, polarization and propagation times of radio signals transmitted from the spacecraft and received with ground station antennas on Earth. The radio signals are affected by the medium through which the signals propagate (atmospheres, ionospheres, interplanetary medium, solar corona), by the gravitational influence of the planet on the spacecraft and

  7. Kinetic investigation of wood pyrolysis

    SciTech Connect

    Thurner, F.; Mann, U.; Beck, S. R.

    1980-06-01

    The objective of this investigation was to determine the kinetics of the primary reactions of wood pyrolysis. A new experimental method was developed which enabled us to measure the rate of gas, tar, and char production while taking into account the temperature variations during the wood heating up. The experimental method developed did not require any sophisticated instruments. It facilitated the collection of gas, tar and residue (unreacted wood and char) as well as accurate measurement of the temperature inside the wood sample. Expressions relating the kinetic parameters to the measured variables were derived. The pyrolysis kinetics was investigated in the range of 300 to 400/sup 0/C at atmospheric pressure and under nitrogen atmosphere. Reaction temperature and mass fractions of gas, tar, and residue were measured as a function of time. Assuming first-order reactions, the kinetic parameters were determined using differential method. The measured activation energies of wood pyrolysis to gas, tar, and char were 88.6, 112.7, and 106.5 kJ/mole, respectively. These kinetic data were then used to predict the yield of the various pyrolysis products. It was found that the best prediction was obtained when an integral-mean temperature obtained from the temperature-time curve was used as reaction temperature. The pyrolysis products were analyzed to investigate the influence of the pyrolysis conditions on the composition. The gas consisted mainly of carbon dioxide, carbon monoxide, oxygen, and C/sub 3//sup +/-compounds. The gas composition depended on reaction time as well as reactor temperature. The tar analysis indicated that the tar consisted of about seven compounds. Its major compound was believed to be levoglucosan. Elemental analysis for the char showed that the carbon content increased with increasing temperature.

  8. Investigation of musicality in birdsong.

    PubMed

    Rothenberg, David; Roeske, Tina C; Voss, Henning U; Naguib, Marc; Tchernichovski, Ofer

    2014-02-01

    Songbirds spend much of their time learning, producing, and listening to complex vocal sequences we call songs. Songs are learned via cultural transmission, and singing, usually by males, has a strong impact on the behavioral state of the listeners, often promoting affiliation, pair bonding, or aggression. What is it in the acoustic structure of birdsong that makes it such a potent stimulus? We suggest that birdsong potency might be driven by principles similar to those that make music so effective in inducing emotional responses in humans: a combination of rhythms and pitches-and the transitions between acoustic states-affecting emotions through creating expectations, anticipations, tension, tension release, or surprise. Here we propose a framework for investigating how birdsong, like human music, employs the above "musical" features to affect the emotions of avian listeners. First we analyze songs of thrush nightingales (Luscinia luscinia) by examining their trajectories in terms of transitions in rhythm and pitch. These transitions show gradual escalations and graceful modifications, which are comparable to some aspects of human musicality. We then explore the feasibility of stripping such putative musical features from the songs and testing how this might affect patterns of auditory responses, focusing on fMRI data in songbirds that demonstrate the feasibility of such approaches. Finally, we explore ideas for investigating whether musical features of birdsong activate avian brains and affect avian behavior in manners comparable to music's effects on humans. In conclusion, we suggest that birdsong research would benefit from current advances in music theory by attempting to identify structures that are designed to elicit listeners' emotions and then testing for such effects experimentally. Birdsong research that takes into account the striking complexity of song structure in light of its more immediate function - to affect behavioral state in listeners - could

  9. Dynamics explorer interdisciplinary scientist investigations

    NASA Technical Reports Server (NTRS)

    Kozyra, Janet U.; Nagy, A. F.

    1994-01-01

    This document is a final report on research activities and accomplishments that occurred during the funding period of 10-1-90 through 1-30-94. The focus of our interdisciplinary investigation during the Dynamics Explorer Mission was on the complex coupling processes that tap the magnetic-storm energy, stored in the ring current particle reservoir, and transport this energy into the subauroral, midlatitude and even equatorial ionospheric regions. The transport of energy through the inner magnetosphere and into the underlying ionospheric regions is a critical element in our understanding of the impact of solar and magnetic disturbances on upper atmospheric and ionospheric regions equatorward of the auroral zone.

  10. Mars Observer magnetic fields investigation

    NASA Technical Reports Server (NTRS)

    Acuna, M. H.; Connerney, J. E. P.; Wasilewski, P.; Lin, R. P.; Anderson, K. A.; Carlson, C. W.; Mcfadden, J.; Curtis, D. W.; Reme, H.; Cros, A.

    1992-01-01

    The magnetic fields experiment designed for the Mars Observer mission will provide definitive measurements of the Martian magnetic field from the transition and mapping orbits planned for the Mars Observer. The paper describes the instruments (which include a classical magnetometer and an electron reflection magnetometer) and techniques designed to investigate the nature of the Martian magnetic field and the Mars-solar wind interaction, the mapping of crustal magnetic fields, and studies of the Martian ionosphere, which are activities included in the Mars Observer mission objectives. Attention is also given to the flight software incorporated in the on-board data processor, and the procedures of data processing and analysis.

  11. Alkaline fuel cell performance investigation

    NASA Technical Reports Server (NTRS)

    Martin, R. E.; Manzo, M. A.

    1988-01-01

    An exploratory experimental fuel cell test program was conducted to investigate the performance characteristics of alkaline laboratory research electrodes. The objective of this work was to establish the effect of temperature, pressure, and concentration upon performance and evaluate candidate cathode configurations having the potential for improved performance. The performance characterization tests provided data to empirically establish the effect of temperature, pressure, and concentration upon performance for cell temperatures up to 300 F and reactant pressures up to 200 psia. Evaluation of five gold alloy cathode catalysts revealed that three doped gold alloys had more that two times the surface areas of reference cathodes and therefore offered the best potential for improved performance.

  12. Alkaline fuel cell performance investigation

    NASA Technical Reports Server (NTRS)

    Martin, R. E.; Manzo, M. A.

    1988-01-01

    An exploratory experimental fuel cell test program was conducted to investigate the performance characteristics of alkaline laboratory research electrodes. The objective of this work was to establish the effect of temperature, pressure, and concentration upon performance and evaluate candidate cathode configurations having the potential for improved performance. The performance characterization tests provided data to empirically establish the effect of temperature, pressure, and concentration upon performance for cell temperatures up to 300 F and reactant pressures up to 200 psia. Evaluation of five gold alloy cathode catalysts revealed that three doped gold alloys had more than two times the surface areas of reference cathodes and therefore offered the best potential for improved performance.

  13. Integrated systems for exosome investigation.

    PubMed

    Peterson, Maureen F; Otoc, Nicole; Sethi, Jasmine K; Gupta, Archana; Antes, Travis J

    2015-10-01

    Extracellular vesicles, including exosomes, are currently being investigated to better understand their biogenesis and biological functions. There is also a rapidly growing interest in utilizing exosomes present in patient biofluids for molecular diagnostics in the clinic. Exosomes are natural shuttles of RNA and protein cargo, making them attractive as potential therapeutic delivery vehicles. Here, we describe the methods for using the latest tools and technologies to study exosomes to better understand their roles in cell-to-cell communication, for discovery of clinical biomarkers and to engineer exosomes for therapeutic applications.

  14. Overview of the Systems Special Investigation Group investigation

    NASA Technical Reports Server (NTRS)

    Mason, James B.; Dursch, Harry; Edelman, Joel

    1993-01-01

    The Long Duration Exposure Facility (LDEF) carried a remarkable variety of electrical, mechanical, thermal, and optical systems, subsystems, and components. Nineteen of the fifty-seven experiments flown on LDEF contained functional systems that were active on-orbit. Almost all of the other experiments possessed at least a few specific components of interest to the Systems Special Investigation Group (Systems SIG), such as adhesives, seals, fasteners, optical components, and thermal blankets. Almost all top level functional testing of the active LDEF and experiment systems has been completed. Failure analysis of both LDEF hardware and individual experiments that failed to perform as designed has also been completed. Testing of system components and experimenter hardware of interest to the Systems SIG is ongoing. All available testing and analysis results were collected and integrated by the Systems SIG. An overview of our findings is provided. An LDEF Optical Experiment Database containing information for all 29 optical related experiments is also discussed.

  15. Measles investigation: a moving target.

    PubMed

    Helmecke, Megan R; Elmendorf, Sarah L; Kent, Donna L; Pauze, Daniel K; Pauze, Denis R

    2014-08-01

    Measles is a highly contagious respiratory infection with significant transmission risk once thought to be on the verge of elimination. Outbreaks in Europe have resulted in resurgence; however, experience with measles is limited in the United States. We describe the impact of 2 measles cases presenting to our emergency department in May 2011. Exposure criteria were defined and revised. Guidance documents were developed and distributed. Suspect cases were masked and escorted to negative pressure. Lack of prompt IgM and polymerase chain reaction testing resulted in delayed disease confirmation. Computerized flagging systems were established. Exposed individuals were screened to determine the need for prophylaxis. Investigation costs were calculated. A total of 171 patients and visitors and 94 employees met exposure criteria. Employees had proof of immunity to measles. Of these, 43 patients and visitors returned for prophylaxis. No subsequent transmission occurred. The conservative cost for these investigations was $63,176.39. Multiple challenges were identified. Inexperience with measles can result in significant outbreaks. Although transmission did occur at another facility, it was prevented at our facility because of rapid case recognition, isolation, health care worker immunity, and multidisciplinary response. Discordance between the Healthcare Infection Control Practices Advisory Committee and public health guidelines for measles control created unnecessary challenges. PMID:24939517

  16. Investigations of SPS Orbit Drifts

    SciTech Connect

    Drøsdal, Lene; Bracco, Chiara; Cornelis, Karel; Goddard, Brennan; Kain, Verena; Meddahi, Malika; Wenninger, Jorg; Gianfelice-Wendt, Eliana

    2014-07-01

    The LHC is filled from the last pre-injector, the Super Proton Synchrotron (SPS), via two 3 km long transfer lines, TI 2 and TI 8. Over the LHC injection processes, a drift of the beam trajectories has been observed in TI 2 and TI 8, requiring regular correction of the trajectories, in order to ensure clean injection into the LHC. Investigations of the trajectory variations in the transfer lines showed that the main source of short term trajectory drifts are current variations of the SPS extraction septa (MSE). The stability of the power converters has been improved, but the variations are still present and further improvements are being investigated. The stability over a longer period of time cannot be explained by this source alone. The analysis of trajectory variations shows that there are also slow variations in the SPS closed orbit at extraction. A set of SPS orbit measurements has been saved and analysed. These observations will be used together with simulations and observed field errors to locate the second source of variations.

  17. Bioanalysis young investigator: Bhagwat Prasad.

    PubMed

    Prasad, Bhagwat; Singh, Saranjit

    2011-06-01

    It gives me immense pleasure to nominate Bhagwat Prasad for the Bioanalysis Young Investigator Award 2011. He was my direct student since he joined the National Institute of Pharmaceutical Education and Research in July 2004 until February 2011. I had been his teacher and later his guide during his Masters and PhD programs. Since March 2011 Bhagwat has been affiliated with the Department of Pharmaceutics, University of Washington, Seattle (WA, USA) as a post-doctoral fellow. His research projects include bioanalysis of transporter proteins in human tissues using modern LC-MS platforms and clinical studies for understanding drug-drug interactions. Under my direct supervision Bhagwat completed his MS (Pharm) and PhD. Bhagwat has used modern qualitative and quantitative LC-MS approaches during his research. He has first-hand experience of using multiple mass spectrometers. He has published several excellent research and review papers in journals such as, European Journal of Pharmaceutical Sciences, Trends in Analytical Chemistry, Journal of Pharmaceutical and Biomedical Analysis and Drug Discovery Today: Therapeutic Strategies. In a nutshell, Bhagwat Prasad is an outstanding bioanalytical researcher. I am deeply impressed by his drive and determination and, therefore, strongly nominate him for the Bioanalysis Young Investigator Award 2011.

  18. Investigation of Heat Transfer From

    NASA Technical Reports Server (NTRS)

    Lewis, James P.; Ruggeri, Robert S.

    1956-01-01

    The convective heat transfer from the surface of an ellipsoidal forebody of fineness ratio 3 and 20-inch maximum diameter was investigated in clear air for both stationary and rotating operation over a range of conditions including air speeds up to 240 knots, rotational speeds up to 1200 rpm, and angles of attack of 0 deg, 3 deg, and 6 deg. The results are presented in the form of heat-transfer coefficients and the correlation of Nusselt and Reynolds numbers. Both a uniform surface temperature and a uniform input heater density distribution were used. The experimental results agree well with theoretical predictions for uniform surface temperature distribution. Complete agreement was not obtained with uniform input heat density in the laminar-flow region because of conduction effects. No significant effects of rotation were obtained over the range of airstream and rotational speeds investigated. Operation at angle of attack had only minor effects on the local heat transfer. Transition from laminar to turbulent heat transfer occurred over a wide range of Reynolds numbers. The location of transition depended primarily on surface roughness and pressure and temperature gradients. Limited transient heating data indicate that the variation of surface temperature with time followed closely an exponential relation.

  19. Investigating legal aspects of cyberbullying.

    PubMed

    Paul, Simone; Smith, Peter K; Blumberg, Herbert H

    2012-11-01

    In the UK schools are required by law to protect students from bullying; the responsibility of teachers to govern such behaviour has been extended outside the school setting to include cyberbullying. In this investigation, cyberbullying in secondary education is explored from the student perspective using a qualitative method of enquiry. Reported awareness and understanding about the legal aspects of cyberbullying are investigated; consideration is given to legislation, cybercrime, children's rights, school sanctions and safeguarding responsibilities. A total of 197 male and female students aged between 11 and 14 years old participated. Despite the availability of information on guidelines and legislation at national, local, and school level, this does not appear to have reached ground level of the individual student. There is a considerable gap between what students should know and what they report to be aware of with regard to legal aspects of cyberbullying. To address concerns of keeping up with the pace of change in cyberbullying, a collaborative approach is required with young people and adults sharing expertise.

  20. Proteomic Investigations into Hemodialysis Therapy.

    PubMed

    Bonomini, Mario; Sirolli, Vittorio; Pieroni, Luisa; Felaco, Paolo; Amoroso, Luigi; Urbani, Andrea

    2015-01-01

    The retention of a number of solutes that may cause adverse biochemical/biological effects, called uremic toxins, characterizes uremic syndrome. Uremia therapy is based on renal replacement therapy, hemodialysis being the most commonly used modality. The membrane contained in the hemodialyzer represents the ultimate determinant of the success and quality of hemodialysis therapy. Membrane's performance can be evaluated in terms of removal efficiency for unwanted solutes and excess fluid, and minimization of negative interactions between the membrane material and blood components that define the membrane's bio(in)compatibility. Given the high concentration of plasma proteins and the complexity of structural functional relationships of this class of molecules, the performance of a membrane is highly influenced by its interaction with the plasma protein repertoire. Proteomic investigations have been increasingly applied to describe the protein uremic milieu, to compare the blood purification efficiency of different dialyzer membranes or different extracorporeal techniques, and to evaluate the adsorption of plasma proteins onto hemodialysis membranes. In this article, we aim to highlight investigations in the hemodialysis setting making use of recent developments in proteomic technologies. Examples are presented of why proteomics may be helpful to nephrology and may possibly affect future directions in renal research. PMID:26690416

  1. QUANTITATIVE INVESTIGATIONS OF IDIOTYPIC ANTIBODIES

    PubMed Central

    Spring, Susan B.; Schroeder, Kenneth W.; Nisonoff, Alfred

    1971-01-01

    The effect of challenge by antigen on persistence of clones of antibody-producing cells and on the induction of new clones was investigated through quantitative measurements of idiotypic specificities. In each of nine rabbits idiotypic specificities present in the earliest bleedings were completely replaced after a few months; subsequent changes occurred much more slowly. On a quantitative basis the population of molecules used as immunogen always reacted most effectively with the homologous anti-idiotypic antiserum. Little effect of increased antigen dose on the rate of change of idiotype was observed. Even large amounts of antigen administered every 2 wk caused only gradual changes in idiotypic specificities. This was attributed either to more effective capture of antigen by memory cells, as compared to precursor cells, or to the induction of tolerance in those clones that were not expressed. In two of three rabbits on a monthly injection schedule, the idiotypic specificities identified underwent very slow changes over a period as long as 17 months. Changes occurred more rapidly when antigen was administered every 2 wk. In each of four rabbits investigated, all idiotypic specificities identified before a 5 month rest period were still present afterwards, indicating the survival of essentially all clones of antibody-producing cells during that interval. Quantitative inhibition data indicated that some new clones of cells were initiated. PMID:15776574

  2. Investigating legal aspects of cyberbullying.

    PubMed

    Paul, Simone; Smith, Peter K; Blumberg, Herbert H

    2012-11-01

    In the UK schools are required by law to protect students from bullying; the responsibility of teachers to govern such behaviour has been extended outside the school setting to include cyberbullying. In this investigation, cyberbullying in secondary education is explored from the student perspective using a qualitative method of enquiry. Reported awareness and understanding about the legal aspects of cyberbullying are investigated; consideration is given to legislation, cybercrime, children's rights, school sanctions and safeguarding responsibilities. A total of 197 male and female students aged between 11 and 14 years old participated. Despite the availability of information on guidelines and legislation at national, local, and school level, this does not appear to have reached ground level of the individual student. There is a considerable gap between what students should know and what they report to be aware of with regard to legal aspects of cyberbullying. To address concerns of keeping up with the pace of change in cyberbullying, a collaborative approach is required with young people and adults sharing expertise. PMID:23079364

  3. Investigation of musicality in birdsong

    PubMed Central

    Rothenberg, David; Roeske, Tina C.; Voss, Henning U.; Naguib, Marc; Tchernichovski, Ofer

    2013-01-01

    Songbirds spend much of their time learning, producing, and listening to complex vocal sequences we call songs. Songs are learned via cultural transmission, and singing, usually by males, has a strong impact on the behavioral state of the listeners, often promoting affiliation, pair bonding, or aggression. What is it in the acoustic structure of birdsong that makes it such a potent stimulus? We suggest that birdsong potency might be driven by principles similar to those that make music so effective in inducing emotional responses in humans: a combination of rhythms and pitches —and the transitions between acoustic states—affecting emotions through creating expectations, anticipations, tension, tension release, or surprise. Here we propose a framework for investigating how birdsong, like human music, employs the above “musical” features to affect the emotions of avian listeners. First we analyze songs of thrush nightingales (Luscinia luscinia) by examining their trajectories in terms of transitions in rhythm and pitch. These transitions show gradual escalations and graceful modifications, which are comparable to some aspects of human musicality. We then explore the feasibility of stripping such putative musical features from the songs and testing how this might affect patterns of auditory responses, focusing on fMRI data in songbirds that demonstrate the feasibility of such approaches. Finally, we explore ideas for investigating whether musical features of birdsong activate avian brains and affect avian behavior in manners comparable to music’s effects on humans. In conclusion, we suggest that birdsong research would benefit from current advances in music theory by attempting to identify structures that are designed to elicit listeners’ emotions and then testing for such effects experimentally. Birdsong research that takes into account the striking complexity of song structure in light of its more immediate function – to affect behavioral state in

  4. Delaminations Investigated With Ultrasonic Spectroscopy

    NASA Technical Reports Server (NTRS)

    Cosgriff, Laura M.

    2003-01-01

    A previous study suggested that the ultrasonic spectroscopy technique identified possible disbonds or delaminations in polymer matrix composite (PMC) rings sectioned from flywheel rotors (ref. 1). These results went unsubstantiated by other nondestructive evaluation (NDE) methods. To explain the results, PMC rings were further investigated with ultrasonic spectroscopy (ref. 2). The ultrasonic spectroscopy system utilizes a continuous-swept sine waveform as the input. After the swept sine wave traverses the material, the captured waveform is subjected to two fast Fourier transforms. The second fast Fourier transform along with equalization of the frequency spectrum, allows for evaluation of the fundamental resonant frequency. The full-thickness resonance, the resonance corresponding to the location of the intentional disbond, and the frequency spectrum were examined in an effort to characterize the sensitivity of the NDE method to various delamination conditions.

  5. Selling Complementary Patents: Experimental Investigation

    SciTech Connect

    Bjornstad, David J; Santore, Rudy; McKee, Michael

    2010-02-01

    Production requiring licensing groups of complementary patents implements a coordination game among patent holders, who can price patents by choosing among combinations of fixed and royalty fees. Summed across patents, these fees become the total producer cost of the package of patents. Royalties, because they function as excise taxes, add to marginal costs, resulting in higher prices and reduced quantities of the downstream product and lower payoffs to the patent holders. Using fixed fees eliminates this inefficiency but yields a more complex coordination game in which there are multiple equilibria, which are very fragile in that small mistakes can lead the downstream firm to not license the technology, resulting in inefficient outcomes. We report on a laboratory market investigation of the efficiency effects of coordinated pricing of patents in a patent pool. We find that pool-like pricing agreements can yield fewer coordination failures in the pricing of complementary patents.

  6. Thermoanalytical investigation of ancient pottery

    NASA Astrophysics Data System (ADS)

    Kotryová, Barbora; Ondruška, Ján; Štubňa, Igor; Bačík, Peter

    2016-07-01

    Ceramic potsherds excavated in Biskupice (Bánovce County, Slovakia) dated to the Hallstatt culture (8th to 6th centuries BC) were investigated by TGA, thermodilatometry (TDA) and XRD analysis. It was found that the samples consisted of illite/muscovite, feldspar and quartz. Their thermal behavior was typical for ceramics buried in soil for a long time: the mass loss (˜3 mass%) due to escaping the physically bound water (from room temperature to 300 °C) was followed by a gradual mass loss from dehydroxylation (˜3 mass%) as a consequence of the former rehydroxylation. Above the temperature 800 °C a rapid shrinkage of samples was observed in TDA curves. As follows from these results, maximal firing temperatures did not exceed 800 °C.

  7. Polarimetric Investigations of Stellar Associations

    NASA Astrophysics Data System (ADS)

    Khachikian, E. Ye.; Eritsian, M. A.; Hovhannessian, R. Kh.

    2002-07-01

    The degree of polarization of light from stars in 44 O B associations as a function of interstellar absorption is investigated. It is shown that the character of the dependence of P on A V for stars in associations and stars not in associations depends on the value of A V: for A V 2 m .5 it has a linear character and is the same for both groups of stars. For A V > 2 m .5 the dependence of P on A V for stars in and not in associations departs from linearity and for A V = 4 m .5 it reaches P ass = 1.8% and P nonass = 1%, respectively. Such a difference is explained by the additional depolarization in stellar associations. Such strong depolarization in associations may be due to the overall magnetic field of the Galaxy and to physical peculiarities in the association itself.

  8. Phytochemical investigation of Turnera diffusa.

    PubMed

    Zhao, Jianping; Pawar, Rahul S; Ali, Zulfiqar; Khan, Ikhlas A

    2007-02-01

    A phytochemical investigation of Turnera diffusa afforded 35 compounds, comprised of flavonoids, terpenoids, saccharides, phenolics, and cyanogenic derivatives, including five new compounds (1-5) and a new natural product (6). These compounds were characterized as luteolin 8-C-E-propenoic acid (1), luteolin 8-C-beta-[6-deoxy-2-O-(alpha-l-rhamnopyranosyl)-xylo-hexopyranos-3-uloside] (2), apigenin 7-O-(6' '-O-p-Z-coumaroyl-beta-d-glucopyranoside) (3), apigenin 7-O-(4' '-O-p-Z-coumaroylglucoside) (4), syringetin 3-O-[beta-d-glucopyranosyl-(1-->6)-beta-d-glucopyranoside] (5), and laricitin 3-O-[beta-d-glucopyranosyl-(1-->6)-beta-d-glucopyranoside] (6). Their structures were determined by spectroscopic and chemical methods. PMID:17284070

  9. Wildlife health and disease investigations

    USGS Publications Warehouse

    Roffe, T.J.; Work, T.M.; Braun, C.E.

    2005-01-01

    Wildlife population management requires knowledge of factors that affect population sustainability. Mortality is one of the most important of those factors. Without a clear understanding of the causes of mortality, decisions by managers of whether or how to intercede may be inappropriate. Wildlife biologists are usually the first to discover, assess, and respond to wildlife mortality. Biologists who make accurate, complete and timely field investigations, and proper collection and shipment of samples to a diagnostic facility are essential for an accurate diagnosis. In combination with wildlife disease specialists, biologists can identify causes of wildlife mortality, detect long-term patterns in factors that affect the survival of populations, and take appropriate corrective action to minimize the impact of some mortality factors on wildlife populations.

  10. Investigation of ultraviolet interstellar extinction

    NASA Technical Reports Server (NTRS)

    Payne, C.; Haramundanis, K. L.

    1973-01-01

    Results concerning interstellar extinction in the ultraviolet are reported. These results were initially obtained by using data from main-sequence stars and were extended to include supergiants and emission stars. The principal finding of the analysis of ultraviolet extinction is not only that it is wavelength dependent, but that if changes with galactic longitude in the U3 passband (lambda sub eff = 1621 A); it does not change significantly in the U2 passband (lambda sub eff = 2308 A). Where data are available in the U4 passband (lambda sub eff = 1537 A), they confirm the rapid rise of extinction in the ultraviolet found by other investigators. However, in all cases, emission stars must be used with great caution. It is important to realize that while extinction continues to rise toward shorter wavelengths in the ultraviolet, including the shortest ultraviolet wavelengths measured (1100 A), it no longer plays an important role in the X-ray region (50 A).

  11. Metabolomics techniques for nanotoxicity investigations.

    PubMed

    Lv, Mengying; Huang, Wanqiu; Chen, Zhipeng; Jiang, Hulin; Chen, Jiaqing; Tian, Yuan; Zhang, Zunjian; Xu, Fengguo

    2015-01-01

    Nanomaterials are commonly defined as engineered structures with at least one dimension of 100 nm or less. Investigations of their potential toxicological impact on biological systems and the environment have yet to catch up with the rapid development of nanotechnology and extensive production of nanoparticles. High-throughput methods are necessary to assess the potential toxicity of nanoparticles. The omics techniques are well suited to evaluate toxicity in both in vitro and in vivo systems. Besides genomic, transcriptomic and proteomic profiling, metabolomics holds great promises for globally evaluating and understanding the molecular mechanism of nanoparticle-organism interaction. This manuscript presents a general overview of metabolomics techniques, summarizes its early application in nanotoxicology and finally discusses opportunities and challenges faced in nanotoxicology. PMID:26168257

  12. Compound chondrules: an experimental investigation

    NASA Astrophysics Data System (ADS)

    Connolly, H. C., Jr.; Hewins, R. H.; Atre, N.; Lofgren, G. E.

    1994-07-01

    Compound chondrules are considered to be the product of collisions between molten chondrules during chondrule formation Wasson, J. T. et al. (1994) have argued that some compound chondrules are formed when a chondrule with an accretional rim experienced a flash-melting event similar to a chondrule-forming event. We have designed experiments to investigate the formation of compound chondrules by both methods. Experiments were performed on a Deltech vertical muffle tube furnace to form synthetic chondrules to use as accretion rim material. For our experimental conditions, it is clear that compound chondrules can only be made by a collisional event. Our changes maintain their spherical shape and produce distinct boundaries between charges that are similar to natural compound chondrules. Furthermore, collision event(s) between chondrules will cause nucleation if they are molten and undercooled, thus producing chondrule textures. Flash melting chondrules with accretionary rims will not produce compound chondrules but will produce new chondrules with new textures.

  13. Rosetta Radio Science Investigations (RSI)

    NASA Astrophysics Data System (ADS)

    Tellmann, Silvia; Pätzold, M.; Häusler, B.; Bird, M. K.

    2006-09-01

    In March 2004 the ROSETTA spacecraft started its journey to the comet P/Churyumov-Gerasimenko. The very ambitious mission will escort the comet for several months in 2015 as it heads towards the sun. The ROSETTA Radio Science Experiment (RSI) uses the radio carrier links of the spacecraft Telemetry, Tracking and Command subsystem at X-band and S-band. The spacecraft is specially equipped with an Ultra-Stable Oscillator (USO) that stabilizes the radio links for a significant improvement of the sensitivity and accuracy of the measurement. RSI is interested in dispersive frequency shifts due to the propagation of the radio signals through ionized media as well as non-dispersive frequency shifts caused by other perturbing forces acting on the spacecraft (gravity field, gas and dust mass flux from the comet). These observations will allow the investigation of the comet's nucleus, its size and shape and the lower harmonics of its gravity field, and the dielectric properties of its surface. In addition the electron content of the cometary coma and the abundance of large dust grains can be determined. The mass and bulk density of the asteroid will be determined during the flyby at asteroid Lutetia in 2010 First results from the commissioning phase and regularly performed measurements allow to assess the sensitivity of the experiment and the ageing of the USO quartz oscillator. These results are compared with the coherent two-way-measurements also recorded during commissioning. Between March and May 2006 ROSETTA moved into superior conjunction with the Sun. This allowed the investigation of the solar corona to derive electron density profiles in the structured corona, solar wind speed and to detect, identify and describe the spatial and temporal evolution of the shockfronts of coronal mass ejections.

  14. Investigation of Celestial Solid Analogs

    NASA Technical Reports Server (NTRS)

    Sievers, A. J.

    2003-01-01

    Our far infrared studies of both hydrophobic and hydrophilic aerogel grains have demonstrated that the mm and sub-mm wave absorption produced by the fundamental two level systems (TLS) mechanism represents a more significant contribution for these open grain structures than for bulk amorphous silicate grains. We found that the region with the anomalous temperature dependence of the spectral index due to the TLS excitations can extend in a fluffy material up to 80 per cm, which is well beyond its typical upper limit for bulk glasses. Currently there is no theoretical explanation for this surprising result. The effects of reduced dimensionality on the optical properties of carbonaceous grains have been studied with a systematic investigation of carbon aerogels. This spectroscopic approach has permitted a more reliable determination of the single grain mass normalized absorption coefficient based on the experimentally determined characteristics of the fluffy material rather than on first principles calculations involving the bulk properties of the substance. Our finding is that the electrical connectivity of the material is the main factor affecting its far infrared absorption coefficient. Another one of the main constituents of the interstellar dust, amorphous ice, has been investigated in the mm-wave region both in the high (HDA) and low (LDA) density amorphous phases and as a function of impurities. We found that doping either phase with ionic (LiCl) or molecular (methanol) impurities decreases the difference in the mm-wave absorption coefficient between the HDA and LDA ice phases so that the HDA spectrum can be used as an analog for impure ice absorption in the far infrared spectral region.

  15. Rotational Investigation of Tropane Alkaloids

    NASA Astrophysics Data System (ADS)

    Cocinero, Emilio J.; Lesarri, Alberto; Ecija, Patricia; Grabow, Jens-Uwe; Fernández, Jose A.; Castano, Fernando

    2010-06-01

    We report an investigation of the rotational spectrum of several tropane alkaloids using the new Balle-Flygare-type FT-MW spectrometer built at the University of the Basque Country. The initial work focused on the azabicycles of tropinone, scopine and scopoline, vaporized using heating methods. For tropinone the spectrum confirmed the presence of equatorial and axial conformers originated by the inversion of the N-methyl group, with the tropane motif adopting a distorted chair configuration. The determination of substitution and effective structures for the two conformers included the 13C, 15N and 18O isotopomers observed in natural abundance. The structures revealed the flexibility and structural changes associated to the N-methyl inversion, mostly a flattening at the nitrogen atom and a simultaneous rising of the carbonyl group in the axial form. The investigation of scopine gave an intense spectrum, but it was inconsistent with the structural models expected for this molecule. The carrier of the new spectrum was later identified as scopoline, generated in situ by an intramolecular reaction at the moderate temperatures of the nozzle. A single conformation was detected for scopoline, with an ether bridge seriously distorting the tropane motif. E. J. Cocinero, A. Lesarri, P. écija, J.-U. Grabow, J. A. Fernández, F. Castaño, in publication, 2010 E. J. Cocinero, A. Lesarri, P. Écija, J.-U. Grabow, J. A. Fernández, F. Castaño, Phys. Chem. Chem. Phys.,in press, 2010

  16. Investigation of superlattice device structures

    NASA Technical Reports Server (NTRS)

    Gergis, I. S.; Manasevit, H. M.; Lin, A. L.; Jones, A. B.

    1985-01-01

    This report describes the investigation of growth properties, and the structure of epitaxial multilayer Si(Si(1x)Ge(x)) films grown on bulk Silicon Substrates. It also describes the fabrication and characterization of MOSFET and MESFET devices made on these epitaxial films. Films were grown in a CVD reactor using hydrides of Si and Ge with H2 and He as carrier gases. Growth temperatures were between 900 C and 1050 C with most films grown at 1000 C. Layer thickness was between 300A and 2000A and total film thickness was between 0.25 micro m and 7 micro m. The Ge content (X) in the alloy layers was between .05 and 0.2. N-type multilayer films grown on (100) p-type Si showed Hall mobility in the range 1000 to 1500 sq cm/v for an average carrier concentration of approx. 10 to the 16th power/cu cm. This is up to 50% higher than the Hall mobility observed in epitaxial Si films grown under the same conditions and with the same average carrier concentration. The mobility enhancement occurred in films with average carrier concentration (n) from 0.7 x 10 to the 16th power to 2 x 10 to the 17th power/cu cm, and total film thickness greater than 1.0 micro m. No mobility enhancement was seen in n-type multilayer films grown on (111) Si or in p-type multilayer films. The structure of the films was investigated was using SEM, TEM, AES, SIMS, and X-ray double crystal diffraction techniques. The film composition profile (AES, SIMS) showed that the transition region between layers is of the order of about 100A. The TEM examination revealed a well defined layered structure with fairly sharp interfaces and good crystalline quality. It also showed that the first few layers of the film (closest to the substrate) are uneven, most probably due to the initial growth pattern of the epitaxial film where growth occurs first in isolated islands that eventually growth and coalesce. The X-ray diffraction measurement determined the elastic strain and strain relief in the alloy layers of the film

  17. Investigation of superlattice device structures

    NASA Astrophysics Data System (ADS)

    Gergis, I. S.; Manasevit, H. M.; Lin, A. L.; Jones, A. B.

    1985-06-01

    This report describes the investigation of growth properties, and the structure of epitaxial multilayer Si(Si(1x)Ge(x)) films grown on bulk Silicon Substrates. It also describes the fabrication and characterization of MOSFET and MESFET devices made on these epitaxial films. Films were grown in a CVD reactor using hydrides of Si and Ge with H2 and He as carrier gases. Growth temperatures were between 900 C and 1050 C with most films grown at 1000 C. Layer thickness was between 300A and 2000A and total film thickness was between 0.25 micro m and 7 micro m. The Ge content (X) in the alloy layers was between .05 and 0.2. N-type multilayer films grown on (100) p-type Si showed Hall mobility in the range 1000 to 1500 sq cm/v for an average carrier concentration of approx. 10 to the 16th power/cu cm. This is up to 50% higher than the Hall mobility observed in epitaxial Si films grown under the same conditions and with the same average carrier concentration. The mobility enhancement occurred in films with average carrier concentration (n) from 0.7 x 10 to the 16th power to 2 x 10 to the 17th power/cu cm, and total film thickness greater than 1.0 micro m. No mobility enhancement was seen in n-type multilayer films grown on (111) Si or in p-type multilayer films. The structure of the films was investigated was using SEM, TEM, AES, SIMS, and X-ray double crystal diffraction techniques. The film composition profile (AES, SIMS) showed that the transition region between layers is of the order of about 100A. The TEM examination revealed a well defined layered structure with fairly sharp interfaces and good crystalline quality. It also showed that the first few layers of the film (closest to the substrate) are uneven, most probably due to the initial growth pattern of the epitaxial film where growth occurs first in isolated islands that eventually growth and coalesce. The X-ray diffraction measurement determined the elastic strain and strain relief in the alloy layers of the film

  18. 32 CFR 637.6 - Customs investigations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.6 Customs investigations. (a... to the military police and investigated by CID or the military police, as appropriate. (b) Military police will receipt for all seized or confiscated U.S. Government property and contraband shipped by...

  19. 32 CFR 637.6 - Customs investigations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.6 Customs investigations. (a... to the military police and investigated by CID or the military police, as appropriate. (b) Military police will receipt for all seized or confiscated U.S. Government property and contraband shipped by...

  20. 32 CFR 637.6 - Customs investigations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.6 Customs investigations. (a... to the military police and investigated by CID or the military police, as appropriate. (b) Military police will receipt for all seized or confiscated U.S. Government property and contraband shipped by...

  1. 32 CFR 637.6 - Customs investigations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.6 Customs investigations. (a... to the military police and investigated by CID or the military police, as appropriate. (b) Military police will receipt for all seized or confiscated U.S. Government property and contraband shipped by...

  2. 32 CFR 637.6 - Customs investigations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.6 Customs investigations. (a... to the military police and investigated by CID or the military police, as appropriate. (b) Military police will receipt for all seized or confiscated U.S. Government property and contraband shipped by...

  3. Interactive investigations into planetary interiors

    NASA Astrophysics Data System (ADS)

    Rose, I.

    2015-12-01

    Many processes in Earth science are difficult to observe or visualize due to the large timescales and lengthscales over which they operate. The dynamics of planetary mantles are particularly challenging as we cannot even look at the rocks involved. As a result, much teaching material on mantle dynamics relies on static images and cartoons, many of which are decades old. Recent improvements in computing power and technology (largely driven by game and web development) have allowed for advances in real-time physics simulations and visualizations, but these have been slow to affect Earth science education.Here I demonstrate a teaching tool for mantle convection and seismology which solves the equations for conservation of mass, momentum, and energy in real time, allowing users make changes to the simulation and immediately see the effects. The user can ask and answer questions about what happens when they add heat in one place, or take it away from another place, or increase the temperature at the base of the mantle. They can also pause the simulation, and while it is paused, create and visualize seismic waves traveling through the mantle. These allow for investigations into and discussions about plate tectonics, earthquakes, hot spot volcanism, and planetary cooling.The simulation is rendered to the screen using OpenGL, and is cross-platform. It can be run as a native application for maximum performance, but it can also be embedded in a web browser for easy deployment and portability.

  4. The Galileo plasma wave investigation

    NASA Technical Reports Server (NTRS)

    Gurnett, D. A.; Kurth, W. S.; Shaw, R. R.; Roux, A.; Gendrin, R.; Kennel, C. F.; Scarf, F. L.; Shawhan, S. D.

    1992-01-01

    The purpose of the Galileo plasma wave investigation is to study plasma waves and radio emissions in the magnetosphere of Jupiter. The plasma wave instrument uses an electric dipole antenna to detect electric fields, and two search coil magnetic antennas to detect magnetic fields. The frequency range covered is 5 Hz to 5.6 MHz for electric fields and 5 Hz to 160 kHz for magnetic fields. Low time-resolution survey spectrums are provided by three on-board spectrum analyzers. In the normal mode of operation the frequency resolution is about 10 percent, and the time resolution for a complete set of electric and magnetic field measurements is 37.33 s. High time-resolution spectrums are provided by a wideband receiver. The wideband receiver provides waveform measurements over bandwidths of 1, 10, and 80 kHz. Compared to previous measurements at Jupiter this instrument has several new capabilities. These new capabilities include (1) both electric and magnetic field measurements to distinguish electrostatic and electromagnetic waves, (2) direction finding measurements to determine source locations, and (3) increased bandwidth for the wideband measurements.

  5. Clinical investigations in primary care.

    PubMed

    de Souza, Leonardo Cruz; Sarazin, Marie; Goetz, Celine; Dubois, Bruno

    2009-01-01

    Alzheimer's disease (AD) is a progressive neurodegenerative disorder that represents the most common form of dementia. The most prominent feature of AD is the decline in cognitive function, with an early impairment of episodic memory. The memory deficit of an AD patient is characterized by the amnestic syndrome of the medial temporal type. As the disease progresses, the condition often manifests in language disorders, visuospatial deficits and executive dysfunctions. Patients often have neuropsychiatric disturbances, as apathy and psychotic symptoms. Loss of autonomy follows cognitive impairment. The clinical diagnosis of AD is based on a complete medical examination with a neuropsychological evaluation. The FCSRT (free and cued selective reminding test) is recommended for the identification of the amnestic syndrome of the medial temporal type, which is defined by: (1) a very poor free recall and (2) a decreased total recall due to an insufficient effect of cueing. The neuropsychological tests should also assess other cognitive functions that may be perturbed in AD, such as executive functions, praxis, visuospatial capacities and language. Neuroimaging and biological exams (genetics, biomarkers) are of great utility in the evaluation. Other medical, neurological, or psychiatric disorders which could account for the impairment in memory and related symptoms must be always investigated. PMID:19182457

  6. Experimental investigations of elastohydrodynamic lubrication

    NASA Technical Reports Server (NTRS)

    Hamrock, B. J.; Dowson, D.

    1983-01-01

    Various experimental studies of elastohydrodynamic lubrication have been reviewed. The various types of machines used in these investigations, such as the disc, two and four ball, crossed-cylinders, and crossed-axes rolling disc machine, are described. The measurement of the most important parameters, such as film shape, film thickness, pressure, temperature, and traction, is considered. Determination of the film thickness is generally the most important of these effects since it dictates the extent to which the asperities on opposing surfaces can come into contact and thus has a direct bearing on wear and fatigue failure of the contacting surfaces. Several different techniques for measuring film thickness have been described, including electrical resistance, capacitance, X-ray, optical interferometry, laser beam diffraction, strain gage, and spring dynamometer methods. An attempt has been made to describe the basic concepts and limitations of each of these techniques. These various methods have been used by individual researchers, but there is no universally acceptable technique for measuring elastohydrodynamic film thickness. Capacitance methods have provided most of the reliable data for nominal line or rectangular conjunctions, but optical interferometry has proved to be the most effective procedure for elliptical contacts. Optical interferometry has the great advantage that it reveals not only the film thickness, but also details of the film shape over the complete area of the conjunction.

  7. Mission Investigates Tropical Cirrus Clouds

    NASA Astrophysics Data System (ADS)

    Jenson, Eric; Starr, David; Toon, Owen B.

    2004-02-01

    It has been a year since NASA conducted the highly successful Cirrus Regional Study of Tropical Anvils and Cirrus Layers-Florida Area Cirrus Experiment Study (CRYSTAL-FACE). The measurement campaign was designed to investigate the physical properties and formation processes of tropical cirrus clouds. CRYSTAL-FACE was sponsored by NASA's Earth Science Enterprise as an integral component of its Earth observation research strategy, and included substantial collaboration with the National Oceanic and Atmospheric Administration, the National Science Foundation, the Department of Energy, and the Naval Research Laboratory. During July 2002, the mission's six aircraft (NASA ER-2, NASA WB-57, Scaled Composites Proteus, University of North Dakota Citation, NSF-supported NRL P-3, and NRL Twin Otter) operated from the Key West Naval Air Facility. In addition, ground sites were located at the Tamiami airport on the east coast of Florida and near Everglades City on the west coast of Florida. Aircraft and ground site measurements are listed in Table 1. Data archiving is complete, and the data are now available to the general scientific community. Detailed instrument descriptions as well as the final data can be found on the CRYSTAL-FACE Web site (http://cloud1.arc.nasa.gov/crystalface/).

  8. Investigation into nitrided spur gears

    SciTech Connect

    Yilbas, B.S.; Coban, A.; Nickel, J.; Sunar, M.; Sami, M.; Abdul Aleem, B.J.

    1996-12-01

    The cold forging method has been widely used in industry to produce machine parts. In general, gears are produced by shaping or hobbing. One of the shaping techniques is precision forging, which has several advantages over hobbing. In the present study, cold forging of spur gears from Ti-6Al-4V material is introduced. To improve the surface properties of the resulting gears, plasma nitriding was carried out. Nuclear reaction analysis was carried out to obtain the nitrogen concentration, while the micro-PIXE technique was used to determine the elemental distribution in the matrix after forging and nitriding processes. Scanning electron microscopy and x-ray powder diffraction were used to investigate the metallurgical changes and formation of nitride components in the surface region. Microhardness and friction tests were carried out to measure the hardness depth profile and friction coefficient at the surface. Finally, scoring failure tests were conducted to determine the rotational speed at which the gears failed. Three distinct regions were obtained in the nitride region, and at the initial stages of the scoring tests, failure in surface roughness was observed in the vicinity of the tip of the gear tooth. This occurred at a particular rotational speed and work input.

  9. Investigating cerebral oedema using poroelasticity.

    PubMed

    Vardakis, John C; Chou, Dean; Tully, Brett J; Hung, Chang C; Lee, Tsong H; Tsui, Po-Hsiang; Ventikos, Yiannis

    2016-01-01

    Cerebral oedema can be classified as the tangible swelling produced by expansion of the interstitial fluid volume. Hydrocephalus can be succinctly described as the abnormal accumulation of cerebrospinal fluid (CSF) within the brain which ultimately leads to oedema within specific sites of parenchymal tissue. Using hydrocephalus as a test bed, one is able to account for the necessary mechanisms involved in the interaction between oedema formation and cerebral fluid production, transport and drainage. The current state of knowledge about integrative cerebral dynamics and transport phenomena indicates that poroelastic theory may provide a suitable framework to better understand various diseases. In this work, Multiple-Network Poroelastic Theory (MPET) is used to develop a novel spatio-temporal model of fluid regulation and tissue displacement within the various scales of the cerebral environment. The model is applied through two formats, a one-dimensional finite difference - Computational Fluid Dynamics (CFD) coupling framework, as well as a two-dimensional Finite Element Method (FEM) formulation. These are used to investigate the role of endoscopic fourth ventriculostomy in alleviating oedema formation due to fourth ventricle outlet obstruction (1D coupled model) in addition to observing the capability of the FEM template in capturing important characteristics allied to oedema formation, like for instance in the periventricular region (2D model).

  10. Investigations on Flexible Multiferroic Composites

    NASA Astrophysics Data System (ADS)

    Roy, Subhasis; Biswas, Bulbul; Majumder, S. B.

    2008-10-01

    Multiferroic ceramics are one of the most attractive materials for the next generation computer memories, smart sensors, and high frequency microelectronic devices. As compared to single phase multiferroic, piezoelectric-magnetostrictive composite materials exhibit larger magnetoelectric coefficients and therefore better suited for practical applications. In the present paper, we have provided a brief introduction on the multiferroic electro-ceramics followed by the outline of recent research trends on these materials. The potentials of flexible polymer-magnetostrictive composite materials, synthesized by economic chemical based processing routes, has been outlined. To make flexible multiferroic composites, cobalt iron oxide (CoFe2O4) (CFO) spinel powders were synthesized by a polymer assisted decomposition route. The cation mixing in as prepared as well as calcined CFO powders were investigated by XRD Rietveld refinement. Guided by the structural refinement results the processing conditions of the powder synthesis were optimized to yield spinal CFO powder with improved magnetic properties. These powders were dispersed into ferroelectric polyvinyledene (PVDF) matrix and the polymer-spinal composite was cast using different weight fractions of the spinel component. The composites were characterized in terms of its structure and microstructure. Preliminary dielectric and magnetic properties of these CFO-polymer composites is reported.

  11. Investigations of Arcjet Flow Thermochemistry

    NASA Technical Reports Server (NTRS)

    Fletcher, Douglas G.; Wercinski, Paul (Technical Monitor)

    1997-01-01

    An experimental and numerical investigation of the thermochemical state of arcjet flows is currently being conducted at NASA Ames Research Center. The experimental approach relies on the use of laser- and emission-spectroscopic diagnostic techniques in three regions of the flow. A fiber optic sensor is used to record spectrally resolved emission signals from the electrode package region, where the flow is most likely to be in thermochemical equilibrium. A second emission diagnostic measurement is made in the shock layer formed over a blunt-body test article placed in the stream, and a CCD camera is used to simultaneously record spectral emission from several measurement locations along the stagnation streamline. Downstream of the nozzle exit, but upstream of the test article, Laser-Induced Fluorescence (LIF) of atomic nitrogen is used to assess the nonequilibrium distribution of flow enthalpy in the free stream. Results from the measurements are compared with predictions from a two-temperature, axisymmetric flow model that solves the nozzle and shock-layer flows.

  12. Supercritical waste oxidation pump investigation

    SciTech Connect

    Thurston, G.; Garcia, K.

    1993-02-01

    This report investigates the pumping techniques and pumping equipment that would be appropriate for a 5,000 gallon per day supercritical water oxidation waste disposal facility. The pumps must boost water, waste, and additives from atmospheric pressure to approximately 27.6 MPa (4,000 psia). The required flow ranges from 10 gpm to less than 0.1 gpm. For the higher flows, many commercial piston pumps are available. These pumps have packing and check-valves that will require periodic maintenance; probably at 2 to 6 month intervals. Several commercial diaphragm pumps were also discovered that could pump the higher flow rates. Diaphragm pumps have the advantage of not requiring dynamic seals. For the lower flows associated with the waste and additive materials, commercial diaphragm pumps. are available. Difficult to pump materials that are sticky, radioactive, or contain solids, could be injected with an accumulator using an inert gas as the driving mechanism. The information presented in this report serves as a spring board for trade studies and the development of equipment specifications.

  13. Scientists Investigate Recent Philippine Landslide

    NASA Astrophysics Data System (ADS)

    Lagmay, Alfredo Mahar A.; Ong, John Burtkenley T.; Fernandez, Dan Ferdinand D.; Lapus, Mark R.; Rodolfo, Raymond S.; Tengonciang, Arlene Mae P.; Soria, Janneli Lea A.; Baliatan, Eden G.; Quimba, Zareth L.; Uichanco, Christopher L.; Paguican, Engielle Mae R.; Remedio, Armelle Reca C.; Lorenzo, Genevieve Rose H.; Avila, Francia B.; Valdivia, Waldemar

    2006-03-01

    A massive landslide devastated the community of Barangay Guinsaugon, Municipality of St. Bernard, Southern Leyte Province, Philippines, at about 10:30 local time on 17 February. The landslide occurred along the steep fault scarp of the Philippine Fault Zone (PFZ) (Figure 1a), a large and active tectonic structure that traverses the entire length of the Philippines [Allen, 1962]. Barangay Guinsaugon is located at the foot of the scarp, directly in the path of the downward moving mass of earth. As of 24 February, the landslide caused 122 confirmed deaths; 1,328 people still are missing. To assist in the search and rescue operations that followed the landside, a team of geologists and physicists from the University of Philippines (UP-Diliman, Quezon City) and Ateneo de Manila University conducted an investigation of this area on 21-25 February. The UP-Ateneo team provided technical advice on the geology, which included the identification of the type and characteristics of the landslide.

  14. Paleoseismic investigations in South Carolina

    SciTech Connect

    Talwani, P.; Rajendran, C.P. . Dept. of Geological Sciences)

    1992-01-01

    In the last decade paleoseismological investigations have been carried out in South Carolina by USC, USGS, and EBASCO. The results of these have led to the detection of over 50 paleoliquefaction features. These are concentrated in the meizoseismal area of the 1886 Charleston earthquake, in the Myrtle Beach-Georgetown area (about 100 km NE of Charleston) and in the Bluffton Hilton Head area (about 100 SW of Charleston). At each location several liquefaction features have been discovered and dated. Radiocarbon dates suggest the occurrence of at least 6 and possibly 7 events in the SC Coastal Plain during the Holocene. In the Bluffton area several locations were associated with events dated at 600, 1,200, 2,200, 3,200, and 5,000 YBP. The 600, 1,200, 3,200, and 5,000 YBP dates were also observed at Charleston. In the northern sites several features dated at 600, 1,200, and 1,800 YBP. The 1,800 YBP event was observed only at the northern site and the 2,200 YBP event only at the southern site. These observations suggest that two sources other than Charleston may have been active in the Holocene, one located 100 km to the NE and another 100 km SW of Charleston.

  15. Weak lensing and cosmological investigation

    NASA Astrophysics Data System (ADS)

    Acquaviva, Viviana

    2005-03-01

    In the last few years the scientific community has been dealing with the challenging issue of identifying the dark energy component. We regard weak gravitational lensing as a brand new, and extremely important, tool for cosmological investigation in this field. In fact, the features imprinted on the Cosmic Microwave Background radiation by the lensing from the intervening distribution of matter represent a pretty unbiased estimator, and can thus be used for putting constraints on different dark energy models. This is true in particular for the magnetic-type B-modes of CMB polarization, whose unlensed spectrum at large multipoles (l ~= 1000) is very small even in presence of an amount of gravitational waves as large as currently allowed by the experiments: therefore, on these scales the lensing phenomenon is the only responsible for the observed power, and this signal turns out to be a faithful tracer of the dark energy dynamics. We first recall the formal apparatus of the weak lensing in extended theories of gravity, introducing the physical observables suitable to cast the bridge between lensing and cosmology, and then evaluate the amplitude of the expected effect in the particular case of a Non-Minimally-Coupled model, featuring a quadratic coupling between quintessence and Ricci scalar.

  16. QUANTITATIVE INVESTIGATIONS OF IDIOTYPIC ANTIBODIES

    PubMed Central

    Hopper, John E.; MacDonald, A. Bruce; Nisonoff, Alfred

    1970-01-01

    Idiotypic antibodies were investigated quantitatively by a method of indirect precipitation, which utilizes labeled F(ab')2 fragments of specifically purified antibenzoate antibody from the donor, anti-antibody, and an antiglobulin reagent. The contribution of allotypic and hidden determinants to these reactions was excluded. Greater fractions of an idiotypic antibody population are precipitated by this method, as compared to direct precipitation, and in two instances large proportions of idiotypic antibodies were detected in populations which failed to form precipitates by double diffusion in agar gel. The greater sensitivity of the indirect method was attributed to its capacity to detect molecules bearing a small number of antigenic determinants. Extensive studies of cross-reactions, carried out by an inhibition technique, failed to reveal any strong reactions of anti-idiotypic antibodies with heterologous antibenzoate antibody preparations, heterologous sera, or IgG, although a few weak cross-reactions were noted. One definite cross-reaction was observed by a direct binding measurement with heterologous antiserum. Antisera prepared in more than one recipient against a single donor preparation reacted with identical or overlapping subpopulations of the donor molecules. Instances in which two recipient antisera reacted with different proportions of the molecules of a single donor provided evidence for the existence of more than one idiotypic antibody population in the antibenzoate antibody of an individual rabbit. PMID:5308065

  17. Student Investigations of Tropospheric Ozone

    NASA Astrophysics Data System (ADS)

    Austin, S.; Johnson, L.; Merrill, J.; Johnson, R.; Renee, B.; Fortney, M.; Renee, D.

    2006-12-01

    Hands-on field work and data collection have been shown to be a major factor in motivating students in the study of geoscience and environmental science. An existing high-altitude balloon program at Medgar Evers College(MEC) has developed a new student research initiative focused on tropospheric ozone profile investigations. This effort was launched with involvement in the Ozonesonde Network Study (IONS) 2006 campaign of coordinated observations organized by the Goddard Space Flight Center (GSFC). The participation was stimulated by a collaboration between faculty at the University of Rhode Island (URI) and faculty at Medgar Evers College, a minority-serving institution. URI provided training, background material, access to lab facilities and continues to assist faculty at MEC in the engagement of minority students in this research experience. Undergraduate and graduate students are involved in all phases of the ozone study including ozonesonde preparation and calibration (URI), launch and communications (Paradox, NY), and data analysis (Medgar Evers College) which is being incorporated into selected courses in Environmental Science, Physical Science and Computer Science. A companion educational project involved high school students with a teacher-mentor in surface ozone measurements using the GLOBE protocol as well as linkages with the ozone profile study. This presentation describes the student-based participation, the URI-MEC collaboration, results from the ozone profiles as well as the details of ongoing curriculum integration and future work. The project is partially supported by the NASA Aura Education and Public Outreach program.

  18. 48 CFR 22.406-8 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Construction 22.406-8 Investigations. Conduct labor standards investigations when available information... Administrator, Wage and Hour Division, to obtain— (i) Investigation and enforcement instructions; or (ii... disclosing material obtained from Labor Department files, other than computations of back wages...

  19. Bioanalysis young investigator: Sathyadevi Venkataramani.

    PubMed

    Venkataramani, Sathyadevi

    2012-05-01

    It is with great pleasure that I am writing to recommend Sathyadevi Venkataramani who works as a Scientist in Integrated BioTherapeutics (IBT). Sathya did her graduate research work at the University of Zurich (Switzerland) where she focused on using various bioanalytical tools to characterize the stability of repeat proteins that are emerging as excellent alternatives to antibody therapy. She successfully published her research findings in journals including Protein Science, Biochemistry and Current Microbiology. As a postdoctoral associate at Stanford University (CA, USA) and as a Scientist in Solus Biosystems (CA, USA), she thoroughly investigated the applications of spectroscopy and chromatography for characterizing the stability of monoclonal antibodies and other therapeutic proteins. Being the first author in all her publications and corresponding author of her last few highlights her highly competent skills (both writing and oral), enthusiasm, research motivation, hard work, scientific capabilities, innovative thinking and the terrific passion in implementing those. I am very impressed that she is serving as an ad-hoc peer reviewer for journals such as Molecular Biology Reports, American Association of Pharmaceutical Scientists PharmSciTech, Research and Reports in Biochemistry and as a Faculty of Biochemistry for Webmed Central. Currently she is leading the protein chemistry group in Integrated BioTherapeutics, Inc. (IBT) and is already in possession of a couple of manuscripts and patents from IBT. Her expertise and unquenchable enthusiasm in the bioanalysis field have tremendously helped to improve the quality and quantity of proteins in IBT. It is a very commendable idea of Bioanalysis to appreciate and recognize the young rising stars of the scientific world and I am very excited and honored to recommend Sathya among those for the year 2012.

  20. [Electrochemical methods for biomedical investigations].

    PubMed

    Shumyantseva, V V; Bulko, T V; Suprun, E V; Kuzikov, A V; Agafonova, L E; Archakov, A I

    2015-01-01

    In the review, authors discussed recently published experimental data concerning highly sensitive electrochemical methods and technologies for biomedical investigations in the postgenomic era. Developments in electrochemical biosensors systems for the analysis of various bio objects are also considered: cytochrome P450s, cardiac markers, bacterial cells, the analysis of proteins based on electro oxidized amino acids as a tool for analysis of conformational events. The electroanalysis of catalytic activity of cytochromes P450 allowed developing system for screening of potential substrates, inhibitors or modulators of catalytic functions of this class of hemoproteins. The highly sensitive quartz crystal microbalance (QCM) immunosensor has been developed for analysis of bio affinity interactions of antibodies with troponin I in plasma. The QCM technique allowed real-time monitoring of the kinetic differences in specific interactions and nonspecific sorption, with out multiple labeling procedures and separation steps. The affinity binding process was characterized by the association (ka) and the dissociation (kd) kinetic constants and the equilibrium association (K) constant, calculated using experimental data. Based on the electroactivity of bacterial cells, the electrochemical system for determination of sensitivity of the microbial cells to antibiotics cefepime, ampicillin, amikacin, and erythromycin was proposed. It was shown that the minimally detectable cell number corresponds to 106 CFU per electrode. The electrochemical method allows estimating the degree of E.coli JM109 cells resistance to antibiotics within 2-5 h. Electrosynthesis of polymeric analogs of antibodies for myoglobin (molecularly imprinted polymer, MIP) on the surface of graphite screen-printed electrodes as sensor elements with o- phenylenediamine as the functional monomer was developed. Molecularly imprinted polymers demonstrate selective complementary binding of a template protein molecule

  1. The MAVEN Magnetic Field Investigation

    NASA Astrophysics Data System (ADS)

    Connerney, J. E. P.; Espley, J.; Lawton, P.; Murphy, S.; Odom, J.; Oliversen, R.; Sheppard, D.

    2015-12-01

    The MAVEN magnetic field investigation is part of a comprehensive particles and fields subsystem that will measure the magnetic and electric fields and plasma environment of Mars and its interaction with the solar wind. The magnetic field instrumentation consists of two independent tri-axial fluxgate magnetometer sensors, remotely mounted at the outer extremity of the two solar arrays on small extensions ("boomlets"). The sensors are controlled by independent and functionally identical electronics assemblies that are integrated within the particles and fields subsystem and draw their power from redundant power supplies within that system. Each magnetometer measures the ambient vector magnetic field over a wide dynamic range (to 65,536 nT per axis) with a resolution of 0.008 nT in the most sensitive dynamic range and an accuracy of better than 0.05 %. Both magnetometers sample the ambient magnetic field at an intrinsic sample rate of 32 vector samples per second. Telemetry is transferred from each magnetometer to the particles and fields package once per second and subsequently passed to the spacecraft after some reformatting. The magnetic field data volume may be reduced by averaging and decimation, when necessary to meet telemetry allocations, and application of data compression, utilizing a lossless 8-bit differencing scheme. The MAVEN magnetic field experiment may be reconfigured in flight to meet unanticipated needs and is fully hardware redundant. A spacecraft magnetic control program was implemented to provide a magnetically clean environment for the magnetic sensors and the MAVEN mission plan provides for occasional spacecraft maneuvers—multiple rotations about the spacecraft x and z axes—to characterize spacecraft fields and/or instrument offsets in flight.

  2. Field investigation of keyblock stability

    SciTech Connect

    Yow, J.L. Jr.

    1985-04-01

    Discontinuities in a rock mass can intersect an excavation surface to form discrete blocks (keyblocks) which can be unstable. This engineering problem is divided into two parts: block identification, and evaluation of block stability. One stable keyblock and thirteen fallen keyblocks were observed in field investigations at the Nevada Test Site. Nine blocks were measured in detail sufficient to allow back-analysis of their stability. Measurements included block geometry, and discontinuity roughness and compressive strength. Back-analysis correctly predicted stability or failure in all but two cases. These two exceptions involved situations that violated the stress assumptions of the stability calculations. Keyblock faces correlated well with known joint set orientations. The effect of tunnel orientation on keyblock frequency was apparent. Back-analysis of physical models successfully predicted block pullout force for two-dimensional models of unit thickness. Two-dimensional (2D) and three-dimensional (3D) analytic models for the stability of simple pyramidal keyblocks were examined. Calculated stability is greater for 3D analyses than for 2D analyses. Calculated keyblock stability increases with larger in situ stress magnitudes, larger lateral stress ratios, and larger shear strengths. Discontinuity stiffness controls block displacement more strongly than it does stability itself. Large keyblocks are less stable than small ones, and stability increases as blocks become more slender. Rock mass temperature decreases reduce the confining stress magnitudes and can lead to failure. The pattern of stresses affecting each block face explains conceptually the occurrence of pyramidal keyblocks that are truncated near their apex.

  3. The MAVEN Magnetic Field Investigation

    NASA Technical Reports Server (NTRS)

    Connerney, J. E. P.; Espley, J.; Lawton, P.; Murphy, S.; Odom, J.; Oliversen, R.; Sheppard, D.

    2014-01-01

    The MAVEN magnetic field investigation is part of a comprehensive particles and fields subsystem that will measure the magnetic and electric fields and plasma environment of Mars and its interaction with the solar wind. The magnetic field instrumentation consists of two independent tri-axial fluxgate magnetometer sensors, remotely mounted at the outer extremity of the two solar arrays on small extensions ("boomlets"). The sensors are controlled by independent and functionally identical electronics assemblies that are integrated within the particles and fields subsystem and draw their power from redundant power supplies within that system. Each magnetometer measures the ambient vector magnetic field over a wide dynamic range (to 65,536 nT per axis) with a quantization uncertainty of 0.008 nT in the most sensitive dynamic range and an accuracy of better than 0.05%. Both magnetometers sample the ambient magnetic field at an intrinsic sample rate of 32 vector samples per second. Telemetry is transferred from each magnetometer to the particles and fields package once per second and subsequently passed to the spacecraft after some reformatting. The magnetic field data volume may be reduced by averaging and decimation, when necessary to meet telemetry allocations, and application of data compression, utilizing a lossless 8-bit differencing scheme. The MAVEN magnetic field experiment may be reconfigured in flight to meet unanticipated needs and is fully hardware redundant. A spacecraft magnetic control program was implemented to provide a magnetically clean environment for the magnetic sensors and the MAVEN mission plan provides for occasional spacecraft maneuvers - multiple rotations about the spacecraft x and z axes - to characterize spacecraft fields and/or instrument offsets in flight.

  4. Raman investigation of diamond films

    SciTech Connect

    Feng, Li-Ming

    1993-12-31

    Extensive Raman investigations were conducted on a wide range of diamond films whose structures were dilineated by optical and confocal microscopy. The Raman Spectra from one extreme of this range indicates a very intense 1331 cm{sup {minus}1} line diagnostic of bulk crystalline diamond. Microscopy of the corresponding film shows the presence of many large true diamond crystallite. The 1331 cm{sup {minus}1} Raman line at the other extreme of the range, however, is virtually absent. It is replaced, at this extreme, by a very broad Raman contour whose maxima occur near 1355 cm{sup {minus}1} and 1575 cm{sup {minus}1}. Optical microscopy now reveals a complete lack of diamond crystallites. The ratio of the integrated Raman intensity of the 1331 cm{sup {minus}1} diamond line to the integral of the entire broad contour extending from {approx}1200 cm{sup {minus}1} to 1800 cm{sup {minus}1}, with maxima near 1355 cm{sup {minus}1} and 1575 cm{sup {minus}1}, was determined. This ratio rises with increasing diamond crystallite size, and it decreases as true diamond crystallites are replaced by diamond-like, but amorphous, hard carbon, which produces the broad Raman contour. The measured intensity ratio was analyzed in terms of a differential equation related to phonon coupling. The increase of the intensity ratio of the 1331 cm{sup {minus}1} diagnostic diamond peak is due to phono-phonon coupling between the diamond crystallites, as the concentration of the amorphous diamond-like carbon decreases. Confocal microscopy indicates many amorphous-like regions interspersed between diamond crystallites which account for the intensity loss, and agree with the Raman intensity measurements. These Raman measurements crystallinity versus amorphous hard-carbon character of thin diamond film.

  5. Athena Mars rover science investigation

    USGS Publications Warehouse

    Squyres, S. W.; Arvidson, R. E.; Baumgartner, E.T.; Bell, J.F.; Christensen, P.R.; Gorevan, S.; Herkenhoff, K. E.; Klingelhofer, G.; Madsen, M.B.; Morris, R.V.; Rieder, R.; Romero, R.A.

    2003-01-01

    Each Mars Exploration Rover carries an integrated suite of scientific instruments and tools called the Athena science payload. The primary objective of the Athena science investigation is to explore two sites on the Martian surface where water may once have been present, and to assess past environmental conditions at those sites and their suitability for life. The remote sensing portion of the payload uses a mast called the Pancam Mast Assembly (PMA) that provides pointing for two instruments: the Panoramic Camera (Pancam), and the Miniature Thermal Emission Spectrometer (Mini-TES). Pancam provides high-resolution, color, stereo imaging, while Mini-TES provides spectral cubes at mid-infrared wavelengths. For in-situ study, a five degree-of-freedom arm called the Instrument Deployment Device (IDD) carries four more tools: a Microscopic Imager (MI) for close-up imaging, an Alpha Particle X-Ray Spectrometer (APXS) for elemental chemistry, a Mo??ssbauer Spectrometer (MB) for the mineralogy of Fe-bearing materials, and a Rock Abrasion Tool (RAT) for removing dusty and weathered surfaces and exposing fresh rock underneath. The payload also includes magnets that allow the instruments to study the composition of magnetic Martian materials. All of the Athena instruments have undergone extensive calibration, both individually and using a set of geologic reference materials that are being measured with all the instruments. Using a MER-like rover and payload in a number of field settings, we have devised operations processes that will enable us to use the MER rovers to formulate and test scientific hypotheses concerning past environmental conditions and habitability at the landing sites. Copyright 2003 by the American Geophysical Union.

  6. QUANTITATIVE INVESTIGATIONS OF IDIOTYPIC ANTIBODIES

    PubMed Central

    Daugharty, Harry; Hopper, John E.; MacDonald, A. Bruce; Nisonoff, Alfred

    1969-01-01

    Specifically purified anti-p-azobenzoate antibodies of the IgG class from individual rabbits were used to elicit anti-idiotypic antibodies in recipient rabbits. Allotypes of each donor and recipient were matched. When polymerized antibodies were used for immunization, more than 80% of the recipients responded with the formation of antibodies that precipitated the monomeric donor antibody. Percentages of precipitable molecules in the donor antibody population (D) varied from 4 to 56. As little as 4% was readily detectable by the Ouchterlony method or precipitin test. Specificity of the reaction was tested by double diffusion in agar gel against a panel of purified antibenzoate antibodies from 14 heterologous rabbits and, quantitatively, in three systems by measurement of the extent of coprecipitation of heterologous, radiolabeled antibenzoate antibodies. No cross-reactions were observed. Reactions were shown to be attributable to antibenzoate antibodies in the donor serum, and contributions of allotypic reactions were excluded. In three systems investigated quantitatively, and in one studied qualitatively, two recipients of the same donor antibody produced anti-antibody that reacted with essentially the same subfraction of the donor antibody population. The findings that only a portion of the D population is immunogenic, and that the same subfraction is frequently immunogenic in different recipients, suggest that the immunogenic population comprises a limited number of homogeneous groups of antibody molecules. This is supported by the small number of bands usually observed by the Ouchterlony technique. Quantitative methods of analysis should provide an approach to the study of cell populations producing antibodies of a particular idiotype. PMID:5347693

  7. The Global Ecosystem Dynamics Investigation

    NASA Astrophysics Data System (ADS)

    Dubayah, R.; Goetz, S. J.; Blair, J. B.; Fatoyinbo, T. E.; Hansen, M.; Healey, S. P.; Hofton, M. A.; Hurtt, G. C.; Kellner, J.; Luthcke, S. B.; Swatantran, A.

    2014-12-01

    Spaceborne lidar has been identified as a key technology by the international ecosystem science community because it enables accurate estimates of canopy structure and biomass and forms the basis for fusion approaches that extend the capabilities of existing and planned radar missions, such as the NASA-ISRO SAR and the ESA BIOMASS mission. The Global Ecosystems Dynamics Investigation Lidar (GEDI Lidar) was recently selected by NASA's Earth Ventures Instrument (EVI) program. From its vantage point on the International Space Station, GEDI Lidar provides high-resolution observations of forest vertical structure and addresses three, core science questions: What is the aboveground carbon balance of the land surface? What role will the land surface play in mitigating atmospheric CO2 in the coming decades? How does ecosystem structure affect habitat quality and biodiversity? GEDI informs these science questions by making billions of lidar waveform observations of canopy structure over its nominal one year mission length. The instrument uses three laser transmitters to produce 14 parallel tracks of 25 m footprints. These canopy measurements are then used to measure biomass and in fusion with radar and other remote sensing data to quantify changes in biomass resulting from disturbance and recovery. GEDI further marries ecosystem structure from lidar with ecosystem modeling to predict the sequestration potential of existing forests and to evaluate the impact of policy-driven afforestation and reforestation actions on sequestering additional carbon. Lastly, GEDI's observations of ecosystem structure provide a mapping of critical habitat metrics at the fine scales required for understanding the patterns, processes, and controls on biodiversity and habitat quality. The selection of GEDI Lidar, when combined with the rapid advancement of new radar missions and the availability of long-term land cover archives from passive optical sensors, ushers in an exciting new era of land

  8. Investigation of a wrongful death.

    PubMed

    Kissling, F; Frankfort, E

    1996-01-01

    This reprint of a 1979 article tells the story of Rosie Jiminez, a 27-year-old Mexican-American woman who died in McAllen General Hospital in Texas on October 3, 1977, from the complications of an illegal abortion. Jiminez was the first reported victim of the Hyde Amendment which cut off federal Medicaid funding for abortion. She was a daughter of migrant workers, a single mother of a 5-year-old daughter, a welfare recipient, a part-time worker, and a university student 6 months from receiving a bachelor's degree in education. When she died, she had a $700 scholarship check in her pocket, but if she had used that money to pay for an abortion, her education would have been curtailed. Initial reports to the US Centers for Disease Control (CDC), the agency charged with monitoring the effects of the Hyde Amendment, indicated that Jiminez had obtained her abortion in Mexico to protect her privacy. Four months of independent investigation uncovered two women who had accompanied Jiminez to a lay midwife who performed the abortion in Texas. The local police did nothing with this information, and only arrested the midwife when abortion activists set up a trap in which she was recorded offering to perform an abortion for $125. The abortionist was sentenced to 3 days in jail and fined $100 but was not charged in Jiminez's death. The CDC included this information in a two-paragraph report but failed to take any other action to determine the scale of morbidity and mortality following the Hyde Amendment. The women of America must refuse to tolerate the death of a single woman because of a lack of funding for abortion.

  9. Tribochemical investigation of microelectronic materials

    NASA Astrophysics Data System (ADS)

    Kulkarni, Milind Sudhakar

    To achieve efficient planarization with reduced device dimensions in integrated circuits, a better understanding of the physics, chemistry, and the complex interplay involved in chemical mechanical planarization (CMP) is needed. The CMP process takes place at the interface of the pad and wafer in the presence of the fluid slurry medium. The hardness of Cu is significantly less than the slurry abrasive particles which are usually alumina or silica. It has been accepted that a surface layer can protect the Cu surface from scratching during CMP. Four competing mechanisms in materials removal have been reported: the chemical dissolution of Cu, the mechanical removal through slurry abrasives, the formation of thin layer of Cu oxide and the sweeping surface material by slurry flow. Despite the previous investigation of Cu removal, the electrochemical properties of Cu surface layer is yet to be understood. The motivation of this research was to understand the fundamental aspects of removal mechanisms in terms of electrochemical interactions, chemical dissolution, mechanical wear, and factors affecting planarization. Since one of the major requirements in CMP is to have a high surface finish, i.e., low surface roughness, optimization of the surface finish in reference to various parameters was emphasized. Three approaches were used in this research: in situ measurement of material removal, exploration of the electropotential activation and passivation at the copper surface and modeling of the synergistic electrochemical-mechanical interactions on the copper surface. In this research, copper polishing experiments were conducted using a table top tribometer. A potentiostat was coupled with this tribometer. This combination enabled the evaluation of important variables such as applied pressure, polishing speed, slurry chemistry, pH, materials, and applied DC potential. Experiments were designed to understand the combined and individual effect of electrochemical interactions

  10. Investigating Reaction-Driven Cracking

    NASA Astrophysics Data System (ADS)

    Kelemen, P. B.; Hirth, G.; Savage, H. M.

    2013-12-01

    for constant volume replacement. Natural examples have fracture energy densities due to strain energy density of 100's of MPa [2]. Despite theory and observation, until now lab experiments on peridotite hydration and carbonation have not produced reaction-driven cracking. Slow kinetics and limited reactive surface area in low porosity samples may be the cause. Also, maximum stress may be limited by 'disjoining pressure', above which nano-films along grain boundaries collapse, and crystal growth essentially ceases [7]. To address these issues, we've begun experiments on analog materials with fast reaction rates, e.g., CaO + H2O = Ca(OH)2, to efficiently investigate the role of confining pressure and other factors on reaction-driven fracture events. Intriguingly, commercially available 'demolition mortar', largely CaO, produces stresses of 70 MPa or more around 1 inch bore holes at room T and P [8], even though there is a free surface at the top of the borehole, and hydration in a 'closed' system creates ~ 40% air-filled pore space. [1] Jamtveit et al EPSL 08 [2] Kelemen & Hirth EPSL 12 [3] Kelemen et al AREPS 11 [4] Aharonov et al JGR 98 [5] Fletcher & Merino GCA 01 [6] Macdonald & Fyfe T'phys 85 [7] Espinosa-Marzal & Scherer GSL Special Papers 10 [8] Laefer et al Mag Concrete Res 10

  11. 10 CFR 13.4 - Investigation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Investigation. 13.4 Section 13.4 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.4 Investigation. (a) If an investigating official concludes that... Operations for enforcement action under the Atomic Energy Act, or to defer initiating an investigation...

  12. 21 CFR 812.45 - Informing investigators.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Informing investigators. 812.45 Section 812.45 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... investigators. A sponsor shall supply all investigators participating in the investigation with copies of...

  13. [Ethics in nursing research and investigation].

    PubMed

    Busquets Alibés, Ester

    2009-12-01

    Investigation is indispensable for the nursing profession because it contributes to the development of the overall set of knowledge the profession has and thereby improves the practical, clinical care given to patients. However if we look into the history of research and investigation, we realize that investigators have not always respected persons' fundamental rights. This article starts with a short introduction which highlights the role played by investigation for the nursing profession. Then the author presents a historical overview on investigation in order to provide insights into the ethical problems related to investigation, and finally the author comments on the main ethical criteria which should be followed during investigation by nurses.

  14. A clinical investigation of the efficacy of a tooth-whitening gel.

    PubMed

    Sielski, Chester; Conforti, Nicholas; Stewart, Bernal; Chaknis, Pat; Petrone, Margaret E; DeVizio, William; Volpe, Anthony R; Proskin, Howard M

    2003-08-01

    The objective of this randomized, controlled, examiner-blind, parallel-group clinical study was to determine whether a tooth-whitening gel (Colgate Simply White Night Clear Whitening Gel) can significantly lighten teeth when used once daily at night, as compared with a commercially available dentifrice. Following a baseline tooth shade evaluation using the VITA Shade Guide, qualifying adult male and female subjects from the Buffalo, New York area were randomized into 2 treatment groups, which were balanced for baseline VITA Shade Guide scores, gender, and age. The treatment groups were: (1) a commercially available dentifrice only; and (2) a tooth-whitening gel in addition to a commercially available dentifrice. Subjects assigned to the 2 groups were given the dentifrice and a soft-bristled toothbrush. In addition, subjects in one of the groups were given the tooth-whitening gel. All subjects were instructed to brush their teeth for 1 minute twice daily (morning and evening) with the dentifrice. The subjects in the group also using the tooth-whitening gel were further instructed to apply the gel once daily at night, as per manufacturer instructions. Evaluations of tooth shade for each subject were repeated after 2 weeks, and again after 3 weeks of product use. In addition, evaluations of tooth shade for subjects using the tooth-whitening gel were later conducted at 6 months after product use. Seventy-five subjects complied with the protocol and completed the study. At the 2-week and 3-week examinations, subjects using the tooth-whitening gel and dentifrice exhibited statistically significant (P < .05) tooth shade lightening relative to baseline tooth shade. Furthermore, at the 2-week and 3-week examinations, subjects using the tooth-whitening gel exhibited statistically significant (P < .05) tooth shade lightening relative to subjects using only the dentifrice. In addition, the 6-month-postuse examination showed that subjects using the tooth-whitening gel exhibited

  15. Design of the e-Vita diabetes mellitus study: effects and use of an interactive online care platform in patients with type 2 diabetes (e-VitaDM-1/ZODIAC-40)

    PubMed Central

    2014-01-01

    Background Due to ongoing rise in need for care for people with chronic diseases and lagging increase in number of care providers, alternative forms of care provision and self-management support are needed. Empowering patients through an online care platform could help to improve patients’ self-management and reduce the burden on the healthcare system. Methods Access to laboratory results and educational modules on diabetes will be offered through a platform for subjects with type 2 diabetes mellitus treated in primary care. Differences in socio-demographic and clinical characteristics between subjects expressing interest vs. disinterest to use the platform will be explored. Platform usage will be tracked and compared. Patient satisfaction and quality of life will be measured by validated questionnaires and economic analyses will be performed. Discussion This study is designed to assess the feasibility of use of an online platform in routine primary healthcare for subjects with type 2 diabetes mellitus in the Netherlands, and to study effects of use of the platform on treatment satisfaction, quality of life and clinical parameters. Although providing access to a online platform is not a novel intervention, usage and effects have not yet been studied in this patient population. Trial registration Trial registration: NCT01570140. PMID:24593656

  16. 48 CFR 1422.406-8 - Investigations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 1422.406-8 Investigations. (a) Labor standards investigations required by FAR 22.406-8 shall...

  17. 48 CFR 1422.406-8 - Investigations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 1422.406-8 Investigations. (a) Labor standards investigations required by FAR 22.406-8 shall...

  18. 48 CFR 1422.406-8 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 1422.406-8 Investigations. (a) Labor standards investigations required by FAR 22.406-8 shall...

  19. 32 CFR 776.84 - Ethics investigation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Ethics investigation. 776.84 Section 776.84 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES PROFESSIONAL... Complaint Processing Procedures § 776.84 Ethics investigation. (a) Whenever an ethics investigation...

  20. Kinesthetic Investigations in the Physics Classroom

    ERIC Educational Resources Information Center

    Whitworth, Brooke A.; Chiu, Jennifer L.; Bell, Randy L.

    2014-01-01

    Creating investigations that allow students to see physics in their everyday world and to be kinesthetically active outside of the traditional physics classroom can be incredibly engaging and effective. The investigations we developed were inquiry investigations in which students engaged in concrete experiences before we discussed the abstract…

  1. Characterising the Cognitive Processes in Mathematical Investigation

    ERIC Educational Resources Information Center

    Yeo, Joseph B. W.; Yeap, Ban Har

    2010-01-01

    Many educators believe that mathematical investigation involves both problem posing and problem solving, but some teachers have taught their students to investigate during problem solving. The confusion about the relationship between investigation and problem solving may affect how teachers teach their students and how researchers conduct their…

  2. 21 CFR 812.45 - Informing investigators.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Informing investigators. 812.45 Section 812.45 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... investigational plan and the report of prior investigations of the device....

  3. 25 CFR 556.4 - Background investigations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of birth, citizenship, gender, all languages (spoken or written); (2) Currently and for the previous... management official and if the second tribe has access to the investigative materials held by the first tribe, the second tribe may update the investigation and update the investigative report under § 556.5(b)...

  4. 25 CFR 556.4 - Background investigations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of birth, citizenship, gender, all languages (spoken or written); (2) Currently and for the previous... management official and if the second tribe has access to the investigative materials held by the first tribe, the second tribe may update the investigation and update the investigative report under § 556.5(b)...

  5. 10 CFR 820.21 - Investigations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Investigations. 820.21 Section 820.21 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES Enforcement Process § 820.21 Investigations. (a) The Director may initiate and conduct investigations and inspections relating to the scope, nature and extent of compliance by a person with the...

  6. A Classroom Investigation into the Catenary

    ERIC Educational Resources Information Center

    Staples, Ed

    2011-01-01

    The quest to find the equation of a catenary makes an ideal investigation for upper secondary students. In the modelling exercise that follows, no knowledge of calculus is required to gain a fairly good understanding of the nature of the curve. This investigation is best described as a scientific investigation--a "hands on" experience that…

  7. Physics. Teacher's Guide. Investigations in Natural Science.

    ERIC Educational Resources Information Center

    Renner, John W.; And Others

    Investigations in Natural Science is a program in secondary school biology, chemistry, and physics based upon the description of science as a quest for knowledge, not the knowledge itself. This teaching guide is designed for use with the 36 physics investigations found in the student manual. These investigations focus on concepts related to:…

  8. Integrating the Sciences to Investigate Groundwater Pollution

    ERIC Educational Resources Information Center

    Grady, Julie R.; Madden, Andrew S.

    2010-01-01

    Investigations that integrate concepts from geological sciences with biology and chemistry are rare. The authors present an investigation that introduces high school students to microbe-mineral interactions by tying together anaerobic respiration, reduction reactions, metal ion solubility, and groundwater pollution. During the investigation,…

  9. 49 CFR 1503.203 - Investigations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Investigations. 1503.203 Section 1503.203 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION... Investigative Procedures § 1503.203 Investigations. (a) General. The Administrator, or a designated...

  10. 33 CFR 116.20 - Detailed investigation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., Bridge Administration Program determines that a Detailed Investigation should be conducted, the District Commander will initiate an investigation that addresses all of the pertinent data regarding the bridge, including information obtained at a public meeting held under § 116.25. As part of the investigation,...

  11. 43 CFR 17.333 - Investigation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., Conciliation, and Enforcement Procedures § 17.333 Investigation. (a) Informal investigation. (1) DOI will... mediation agreement. (2) As part of the initial investigation, DOI will use informal fact finding methods... possible, settle the complaint on terms that are mutually agreeable to the parties. DOI may seek...

  12. 29 CFR 24.104 - Investigation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., other than the complainant, in accordance with 29 CFR part 70. (d) Investigation under the six... paragraph sets forth the procedures applicable to investigations under the Safe Drinking Water Act; Federal... protected activity. (e) Investigation under the Energy Reorganization Act. In addition to the...

  13. Biology. Teacher's Guide. Investigations in Natural Science.

    ERIC Educational Resources Information Center

    Renner, John W.; And Others

    Investigations in Natural Science is a program in secondary school biology, chemistry, and physics based upon the description of science as a quest for knowledge, not the knowledge itself. This teaching guide is designed for use with the 18 biology investigations found in the student manual. These investigations focus on concepts related to:…

  14. Chemistry. Teacher's Guide. Investigations in Natural Science.

    ERIC Educational Resources Information Center

    Renner, John W.; And Others

    Investigations in Natural Science is a program in secondary school biology, chemistry, and physics based upon the description of science as a quest for knowledge, not the knowledge itself. This teaching guide is designed for use with the 19 chemistry investigations found in the student manual. These investigations focus on concepts related to:…

  15. 48 CFR 22.406-8 - Investigations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 22.406-8 Investigations. Conduct labor standards investigations when available information indicates such action is warranted. In addition, the Department of Labor may conduct an investigation on...

  16. 48 CFR 22.406-8 - Investigations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 22.406-8 Investigations. Conduct labor standards investigations when available information indicates such action is warranted. In addition, the Department of Labor may conduct an investigation on...

  17. 12 CFR 269b.240 - The investigation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false The investigation. 269b.240 Section 269b.240 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM CHARGES OF UNFAIR LABOR PRACTICES Preliminary Investigation § 269b.240 The investigation. (a) The...

  18. 12 CFR 269b.240 - The investigation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false The investigation. 269b.240 Section 269b.240 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM CHARGES OF UNFAIR LABOR PRACTICES Preliminary Investigation § 269b.240 The investigation. (a) The...

  19. 12 CFR 269b.240 - The investigation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false The investigation. 269b.240 Section 269b.240 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) CHARGES OF UNFAIR LABOR PRACTICES Preliminary Investigation § 269b.240 The investigation. (a)...

  20. 12 CFR 269b.240 - The investigation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false The investigation. 269b.240 Section 269b.240 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) CHARGES OF UNFAIR LABOR PRACTICES Preliminary Investigation § 269b.240 The investigation. (a)...

  1. 12 CFR 269b.240 - The investigation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 4 2012-01-01 2012-01-01 false The investigation. 269b.240 Section 269b.240 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) CHARGES OF UNFAIR LABOR PRACTICES Preliminary Investigation § 269b.240 The investigation. (a)...

  2. 18 CFR 1b.6 - Preliminary investigations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Preliminary investigations. 1b.6 Section 1b.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.6 Preliminary investigations....

  3. 18 CFR 1b.5 - Formal investigations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Formal investigations. 1b.5 Section 1b.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.5 Formal investigations....

  4. 18 CFR 1b.6 - Preliminary investigations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Preliminary investigations. 1b.6 Section 1b.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.6 Preliminary investigations....

  5. 18 CFR 1b.6 - Preliminary investigations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Preliminary investigations. 1b.6 Section 1b.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.6 Preliminary investigations....

  6. 18 CFR 1b.5 - Formal investigations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Formal investigations. 1b.5 Section 1b.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.5 Formal investigations....

  7. 18 CFR 1b.5 - Formal investigations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Formal investigations. 1b.5 Section 1b.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.5 Formal investigations....

  8. 18 CFR 1b.6 - Preliminary investigations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Preliminary investigations. 1b.6 Section 1b.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.6 Preliminary investigations....

  9. 18 CFR 1b.5 - Formal investigations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Formal investigations. 1b.5 Section 1b.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.5 Formal investigations....

  10. 37 CFR 11.22 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) The OED Director is authorized to investigate possible grounds for discipline. An investigation may be... possible grounds for discipline. Neither unwillingness nor neglect by a grievant to prosecute a charge, nor... investigation. (b) Any person possessing information or evidence concerning possible grounds for discipline of...

  11. 18 CFR 1b.6 - Preliminary investigations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Preliminary investigations. 1b.6 Section 1b.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.6 Preliminary investigations....

  12. 18 CFR 1b.5 - Formal investigations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Formal investigations. 1b.5 Section 1b.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.5 Formal investigations....

  13. Giochi, scommesse sulla vita, tabelle di mortalità, nascita del calcolo probabilistico, statistica e teoria delle popolazioni.

    PubMed

    Fenaroli, G; Garibaldi, U; Penco, M A

    1981-01-01

    The authors review the work of Huygens, de Witt, Graunt, and others concerning the effects of chance on human life events. Topics considered include duration of life and annuity income, mortality wagering, population theories, and gambling theory.

  14. Historia magistra vitae (Cic. De or. 2.36). The Prime Objective of Radiosurgery in Acoustic Neurinomas.

    PubMed

    Valentino, V; Benassi, M; Strigari, L

    2006-11-30

    The central question of stereotaxic radiosurgery in acoustic neurinomas is how to pinpoint its main objective: is it a better alternative to neurosurgery or an option when surgery is unfeasible? This study is a continuation of the article published in 1995 in Acta Neurochirurgica, but benefits from greater experience, more complete analysis and longer supervision of results. The conclusions that can be drawn to date from our own findings and from others in the literature are the following: radiosurgery can be used not only to prevent neurinoma growth and at the same time to preserve the patient's neurological conditions without the risk of complications, but it can also be counted on to provide a cure. However, radiosurgery as an excising device is more insidious than the microsurgical scalpel, since the narrow beam of radiation, directed to a limited target without opening the skull, is invisible. The expression coined by Lars Leksell regarded precisely the innovation he himself conceived in the 'closed skull operation', with reference to its use in cases of acoustic neurinoma as an alternative to traditional surgery. Hence, whatever technique or instruments are involved, it is always a question of interventional neuroradiology or minimally invasive neurosurgery.

  15. Nootropic (medhya) effect of Bhāvita Śaṇkhapuṣpī tablets: A clinical appraisal

    PubMed Central

    Amin, Hetal; Sharma, Rohit; Vyas, Hitesh; Vyas, Mahesh; Prajapati, P. K.; Dwivedi, Rambabu

    2014-01-01

    Background: Nootropic (medhya) potential of śaṅkhapuṣpī (Convolvulus pluricaulis Choisy.) is reported in Ayurvedic literature and modern studies are now validating the same. In spite of plentiful preclinical researches already carried out during the past decades, only meager clinical efforts exploring its nootropic activity have been reported. Present clinical study is an attempt to evaluate the nootropic effect of Śaṅkhapuṣpī tablets. Aims and Objective: To evaluate the nootropic effect of śaṅkhapuṣpī tablets prepared by three Bhāvanā (levigation) of its cūrṇa (powder) with its own Svarasa (fresh juice). Materials and Methods: Thirty volunteers between the age 16 and 25 years participated in this single group pre-post study. Weschler's memory scale was adopted to collect data before (pre) and after (post) intervention period (2 months). Paired t-test was used for analyzing the data. Results: In auditory immediate test and delayed test, 41.03% and 48% improvement was found which statistically highly significant (<0.001). In visual immediate and delayed test 32.5% and 44.87% improvement was found respectively, which shows highly significant result (<0.001). Conclusion: Results reveal that śaṅkhapuṣpī tablet shown highly significant results in improving memory, especially in long term memory loss in younger age group. PMID:25861147

  16. 76 FR 56455 - DaVita, Inc.; Analysis of Agreement Containing Consent Orders To Aid Public Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... management contract in 22 markets across the United States. The Consent Agreement has been placed on the... be able to exercise unilateral market power. The evidence shows that health insurance companies and... your comment. Your comment--including your name and your state--will be placed on the public record...

  17. Clinical investigation program, fiscal year 1991

    NASA Astrophysics Data System (ADS)

    Schydlower, Manuel

    1992-02-01

    Subject report identifies the research activities conducted at William Beaumont Army Medical Center by investigators who had protocols approved by the Clinical Investigation Committee, the Institutional Review Board, and the Animal Use Committee. This report includes all protocols registered with the Department of Clinical Investigation during FY 1991. All known presentations and publications are also included. The research protocols described were conducted under the provisions of AR 40-38 (Clinical Investigation Program); AR 40-7 (Use of Investigational Drugs in Humans and the Use of Schedule 1 Controlled Substances); AR 70-25 (Usle of Volunteers as Subjects of Research); HSC 40-32 (Management of Clinical Investigation Protocols and Reports); and AR 70-18 (The Use of Animals in DOS programs).

  18. 32 CFR 537.8 - Investigation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Investigation. 537.8 Section 537.8 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY CLAIMS AND ACCOUNTS CLAIMS ON BEHALF OF THE UNITED STATES § 537.8 Investigation. (a) Claims over $50,000. Hands-on investigation will be conducted by claims personnel as set forth in DA...

  19. 32 CFR 537.8 - Investigation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 3 2012-07-01 2009-07-01 true Investigation. 537.8 Section 537.8 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY CLAIMS AND ACCOUNTS CLAIMS ON BEHALF OF THE UNITED STATES § 537.8 Investigation. (a) Claims over $50,000. Hands-on investigation will be conducted by claims personnel as set forth in DA...

  20. Advanced Propulsion Physics Lab: Eagleworks Investigations

    NASA Technical Reports Server (NTRS)

    Scogin, Tyler

    2014-01-01

    Eagleworks Laboratory is an advanced propulsions physics laboratory with two primary investigations currently underway. The first is a Quantum Vacuum Plasma Thruster (QVPT or Q-thrusters), an advanced electric propulsion technology in the development and demonstration phase. The second investigation is in Warp Field Interferometry (WFI). This is an investigation of Dr. Harold "Sonny" White's theoretical physics models for warp field equations using optical experiments in the Electro Optical laboratory (EOL) at Johnson Space Center. These investigations are pursuing technology necessary to enable human exploration of the solar system and beyond.

  1. 48 CFR 1322.406-8 - Investigations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 1322.406-8 Investigations. The designee authorized to process a contracting officer's report on...

  2. 48 CFR 1322.406-8 - Investigations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 1322.406-8 Investigations. The designee authorized to process a contracting officer's report on...

  3. 48 CFR 1322.406-8 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 1322.406-8 Investigations. The designee authorized to process a contracting officer's report on...

  4. History Scene Investigations: From Clues to Conclusions

    ERIC Educational Resources Information Center

    McIntyre, Beverly

    2011-01-01

    In this article, the author introduces a social studies lesson that allows students to learn history and practice reading skills, critical thinking, and writing. The activity is called History Scene Investigation or HSI, which derives its name from the popular television series based on crime scene investigations (CSI). HSI uses discovery learning…

  5. 50 CFR 300.41 - Investigation notification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Investigation notification. 300.41 Section 300.41 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.41 Investigation notification. Upon commencement of...

  6. Earth Control and Investigations, Training Course 1972.

    ERIC Educational Resources Information Center

    Department of the Interior, Denver, CO. Engineering and Research Center.

    Compiled in this notebook is material from an Earth Control and Investigations Course offered by the Earth Science Branch of the Division of General Research, Engineering and Research Center, Denver, Colorado. The training is designed to promote consistency and uniformity in control and investigation procedures throughout the Bureau of…

  7. 77 FR 51943 - Procedures for Safety Investigations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ... Investigations, which published July 27, 2012 in the Federal Register, 77 FR 44174. The comment period expires... SAFETY BOARD 10 CFR Part 1708 Procedures for Safety Investigations AGENCY: Defense Nuclear Facilities Safety Board. ACTION: Proposed rule; extension of comment period. SUMMARY: The Defense Nuclear...

  8. 49 CFR 659.35 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., at a minimum, any incident involving a rail transit vehicle or taking place on rail transit... rail transit agency to conduct investigations on its behalf, it must do so formally and require the rail transit agency to use investigation procedures that have been formally approved by the...

  9. 49 CFR 659.35 - Investigations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., at a minimum, any incident involving a rail transit vehicle or taking place on rail transit... rail transit agency to conduct investigations on its behalf, it must do so formally and require the rail transit agency to use investigation procedures that have been formally approved by the...

  10. 49 CFR 659.35 - Investigations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., at a minimum, any incident involving a rail transit vehicle or taking place on rail transit... rail transit agency to conduct investigations on its behalf, it must do so formally and require the rail transit agency to use investigation procedures that have been formally approved by the...

  11. 49 CFR 659.35 - Investigations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., at a minimum, any incident involving a rail transit vehicle or taking place on rail transit... rail transit agency to conduct investigations on its behalf, it must do so formally and require the rail transit agency to use investigation procedures that have been formally approved by the...

  12. 49 CFR 659.35 - Investigations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., at a minimum, any incident involving a rail transit vehicle or taking place on rail transit... rail transit agency to conduct investigations on its behalf, it must do so formally and require the rail transit agency to use investigation procedures that have been formally approved by the...

  13. Coordinating investigations of suspected notifiable diseases.

    PubMed

    2016-02-27

    The APHA's Veterinary Exotic Notifiable Diseases Unit (VENDU) is a team of vets and scientists that coordinates the investigation of suspected exotic notifiable disease in Great Britain. This article describes the work of the unit and provides a breakdown of the reports investigated in 2015. PMID:26917837

  14. 16 CFR 1605.6 - Investigational hearings.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Investigational hearings. 1605.6 Section 1605.6 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS INVESTIGATIONS, INSPECTIONS AND INQUIRIES PURSUANT TO THE FLAMMABLE FABRICS ACT Procedures for...

  15. 16 CFR 1605.6 - Investigational hearings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Investigational hearings. 1605.6 Section 1605.6 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS INVESTIGATIONS, INSPECTIONS AND INQUIRIES PURSUANT TO THE FLAMMABLE FABRICS ACT Procedures for...

  16. 16 CFR 1605.6 - Investigational hearings.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Investigational hearings. 1605.6 Section 1605.6 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS INVESTIGATIONS, INSPECTIONS AND INQUIRIES PURSUANT TO THE FLAMMABLE FABRICS ACT Procedures for...

  17. 16 CFR 1605.6 - Investigational hearings.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Investigational hearings. 1605.6 Section 1605.6 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS INVESTIGATIONS, INSPECTIONS AND INQUIRIES PURSUANT TO THE FLAMMABLE FABRICS ACT Procedures for...

  18. 16 CFR 1605.6 - Investigational hearings.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Investigational hearings. 1605.6 Section 1605.6 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS INVESTIGATIONS, INSPECTIONS AND INQUIRIES PURSUANT TO THE FLAMMABLE FABRICS ACT Procedures for...

  19. Earth Control and Investigations: Training Course 1974.

    ERIC Educational Resources Information Center

    Department of the Interior, Denver, CO. Engineering and Research Center.

    This document contains the outlines of each of 34 lectures given in the Earth Control and Investigations course sponsored by the Denver Laboratories. Topics covered include construction control of earth dams, canals, and filters; field and laboratory test procedures; soil classification and logging; and field investigations. (DT)

  20. 50 CFR 300.41 - Investigation notification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Investigation notification. 300.41 Section 300.41 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.41 Investigation notification. Upon commencement of...

  1. 18 CFR 808.12 - Investigative powers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Investigative powers. 808.12 Section 808.12 Conservation of Power and Water Resources SUSQUEHANNA RIVER BASIN COMMISSION HEARINGS AND ENFORCEMENT ACTIONS Compliance and Enforcement § 808.12 Investigative powers. (a)...

  2. 77 FR 60440 - Clinical Investigator Training Course

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... regulatory aspects of clinical trials. This training course is intended to provide clinical investigators with expertise in the design, conduct, and analysis of clinical trials; improve the quality of clinical... access to electrical outlets. I. Background Clinical trial investigators play a critical role in...

  3. 75 FR 57472 - Clinical Investigator Training Course

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... Programs, in cosponsorship with the Clinical Trials Transformation Initiative (CTTI), is announcing a 3-day... clinical trials (clinical investigators). This course is intended to assist clinical investigators in... clinical trials. DATES: The training course will be held on November 8 and 9, 2010, from 8 a.m. to 5...

  4. Scaffolding Students' Thinking in Mathematical Investigations

    ERIC Educational Resources Information Center

    McCosker, Natalie; Diezmann, Carmel M.

    2009-01-01

    Mathematical investigations are loosely-defined, engaging problem-solving tasks that allow students to ask their own questions, explore their own interests and set their own goals. The value of investigations for students lies in their complexity. Scaffolding plays an important role in supporting students' high-level engagement by encouraging…

  5. Investigating Elementary Teachers' Conceptions of Animal Classification

    ERIC Educational Resources Information Center

    Burgoon, Jacob N.; Duran, Emilio

    2012-01-01

    Numerous studies have been conducted regarding alternative conceptions about animal diversity and classification, many of which have used a cross-age approach to investigate how students' conceptions change over time. None of these studies, however, have investigated teachers' conceptions of animal classification. This study was intended to…

  6. 40 CFR 7.120 - Complaint investigations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... recipients of Federal assistance (see 28 CFR part 42, subpart H and 29 CFR part 1691). Complaints of... with the Equal Employment Opportunity Commission (see 29 CFR part 1626). Complainants are encouraged... Compliance Procedures § 7.120 Complaint investigations. The OCR shall promptly investigate all...

  7. Teaching Adult Students Mathematical Investigations-6.

    ERIC Educational Resources Information Center

    Angiama, R. O.

    Teaching Adult Students Mathematical Investigation is based on the continuing research work carried out for the last ten years of teaching on the Foundation Course in Mathematics at Goldsmiths, University of London. Teaching Mathematical Investigation to adult students is a very challenging and often rewarding experience for adult educators as…

  8. Investigating Shareable Feedback Tags for Programming Assignments

    ERIC Educational Resources Information Center

    Cummins, Stephen; Burd, Liz; Hatch, Andrew

    2011-01-01

    This article presents an investigation into the usage of shareable feedback tags as a way of delivering feedback to three different cohorts of programming students. A series of research questions are examined; these include investigating any perceived benefit from students using feedback tags and exploring how students interact with their…

  9. 46 CFR 502.281 - Investigational policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... establish procedures for the conduct of such investigations which will insure protection of the public interest in the proper and effective administration of the law. The Commission encourages voluntary cooperation in its investigations where such can be effected without delay or without prejudice to the...

  10. 21 CFR 812.25 - Investigational plan.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Investigational plan. 812.25 Section 812.25 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... plan. The investigational plan shall include, in the following order: (a) Purpose. The name...

  11. Investigation of Propulsive Aspects of Mach Effects

    SciTech Connect

    Woodward, James F.

    2009-03-16

    Results of a continuing investigation of the propulsive potential of Mach effects - the fluctuation of the rest masses of objects that store internal energy as they are accelerated by external forces - obtained in the past year or so are reported. Two chief lines of investigation have been pursued: testing Mach-Lorentz thrusters (MLTs) and exploration of the 'bulk acceleration' conjecture.

  12. Investigating School Leadership Practice: A Distributed Perspective.

    ERIC Educational Resources Information Center

    Spillane, James P.; Halverson, Richard; Diamond, John B.

    2001-01-01

    Argues for scholarship that investigates leadership practice; specifically, the practice of leading classroom instruction. Articulates a distributed perspective, grounded in activity theory and distributed cognition, to frame such investigations. Suggests that school leadership is best understood as a distributed practice stretched over the…

  13. 41 CFR 105-70.004 - Investigation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... allegations directly to the Department of Justice for suit under the False Claims Act or other civil relief... criminal investigation or prosecution. (d) Nothing in this section modifies any responsibility of an investigating official to report violations of criminal law to the Attorney General....

  14. 40 CFR 27.4 - Investigation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Investigation. 27.4 Section 27.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROGRAM FRAUD CIVIL REMEDIES § 27.4... official to avoid interference with a criminal investigation or prosecution. (d) Nothing in this...

  15. 40 CFR 27.4 - Investigation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Investigation. 27.4 Section 27.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROGRAM FRAUD CIVIL REMEDIES § 27.4... official to avoid interference with a criminal investigation or prosecution. (d) Nothing in this...

  16. 22 CFR 304.6 - Claims investigation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Claims investigation. 304.6 Section 304.6 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.6 Claims investigation. (a) When a claim has been filed with the Peace Corps, the General Counsel will...

  17. 22 CFR 304.6 - Claims investigation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Claims investigation. 304.6 Section 304.6 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.6 Claims investigation. (a) When a claim has been filed with the Peace Corps, the General Counsel will...

  18. 22 CFR 304.6 - Claims investigation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Claims investigation. 304.6 Section 304.6 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.6 Claims investigation. (a) When a claim has been filed with the Peace Corps, the General Counsel will...

  19. 16 CFR 1118.5 - Investigational hearings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1118.5 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS INVESTIGATIONS, INSPECTIONS AND INQUIRIES UNDER THE CONSUMER PRODUCT SAFETY ACT Procedures for Investigations... more of the Commissioners, by an administrative law judge, or by a duly designated officer or...

  20. DNA Barcoding Investigations Bring Biology to Life

    ERIC Educational Resources Information Center

    Musante, Susan

    2010-01-01

    This article describes how DNA barcoding investigations bring biology to life. Biologists recognize the power of DNA barcoding not just to teach biology through connections to the real world but also to immerse students in the exciting process of science. As an investigator in the Program for the Human Environment at Rockefeller University in New…

  1. 29 CFR 24.104 - Investigation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF THE ENERGY REORGANIZATION ACT OF 1974, AS AMENDED... paragraph sets forth the procedures applicable to investigations under the Safe Drinking Water Act; Federal... Energy Reorganization Act. In addition to the investigative procedures set forth in §§ 24.104(a), (b),...

  2. 29 CFR 24.104 - Investigation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF THE ENERGY REORGANIZATION ACT OF 1974, AS AMENDED... paragraph sets forth the procedures applicable to investigations under the Safe Drinking Water Act; Federal... Energy Reorganization Act. In addition to the investigative procedures set forth in §§ 24.104(a), (b),...

  3. 29 CFR 24.104 - Investigation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF THE ENERGY REORGANIZATION ACT OF 1974, AS AMENDED... paragraph sets forth the procedures applicable to investigations under the Safe Drinking Water Act; Federal... Energy Reorganization Act. In addition to the investigative procedures set forth in §§ 24.104(a), (b),...

  4. 29 CFR 24.104 - Investigation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF THE ENERGY REORGANIZATION ACT OF 1974, AS AMENDED... paragraph sets forth the procedures applicable to investigations under the Safe Drinking Water Act; Federal... Energy Reorganization Act. In addition to the investigative procedures set forth in §§ 24.104(a), (b),...

  5. 21 CFR 812.46 - Monitoring investigations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... signed agreement, the investigational plan, the requirements of this part or other applicable FDA regulations, or any conditions of approval imposed by the reviewing IRB or FDA shall promptly either secure... sponsor may not resume a terminated investigation without IRB and FDA approval. If the device is not...

  6. 21 CFR 812.46 - Monitoring investigations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... signed agreement, the investigational plan, the requirements of this part or other applicable FDA regulations, or any conditions of approval imposed by the reviewing IRB or FDA shall promptly either secure... sponsor may not resume a terminated investigation without IRB and FDA approval. If the device is not...

  7. 21 CFR 812.46 - Monitoring investigations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... signed agreement, the investigational plan, the requirements of this part or other applicable FDA regulations, or any conditions of approval imposed by the reviewing IRB or FDA shall promptly either secure... sponsor may not resume a terminated investigation without IRB and FDA approval. If the device is not...

  8. 21 CFR 812.46 - Monitoring investigations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... signed agreement, the investigational plan, the requirements of this part or other applicable FDA regulations, or any conditions of approval imposed by the reviewing IRB or FDA shall promptly either secure... sponsor may not resume a terminated investigation without IRB and FDA approval. If the device is not...

  9. 21 CFR 812.46 - Monitoring investigations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... signed agreement, the investigational plan, the requirements of this part or other applicable FDA regulations, or any conditions of approval imposed by the reviewing IRB or FDA shall promptly either secure... sponsor may not resume a terminated investigation without IRB and FDA approval. If the device is not...

  10. 45 CFR 689.6 - Investigations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Investigations. 689.6 Section 689.6 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION RESEARCH MISCONDUCT § 689.6 Investigations. (a) When an awardee institution or another Federal agency has promptly initiated its...

  11. 45 CFR 689.6 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Investigations. 689.6 Section 689.6 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION RESEARCH MISCONDUCT § 689.6 Investigations. (a) When an awardee institution or another Federal agency has promptly initiated its...

  12. 29 CFR 32.45 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Investigations. 32.45 Section 32.45 Labor Office of the Secretary of Labor NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Procedures § 32.45 Investigations. (a) Periodic compliance reviews. The Assistant Secretary shall from time-to-time review...

  13. 50 CFR 300.41 - Investigation notification.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 11 2012-10-01 2012-10-01 false Investigation notification. 300.41 Section 300.41 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.41 Investigation notification. Upon commencement of...

  14. 50 CFR 300.41 - Investigation notification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 11 2014-10-01 2014-10-01 false Investigation notification. 300.41 Section 300.41 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.41 Investigation notification. Upon commencement of...

  15. 50 CFR 300.41 - Investigation notification.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Investigation notification. 300.41 Section 300.41 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.41 Investigation notification. Upon commencement of...

  16. 45 CFR 689.6 - Investigations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Investigations. 689.6 Section 689.6 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION RESEARCH MISCONDUCT § 689.6 Investigations. (a) When an awardee institution or another Federal agency has promptly initiated its...

  17. 45 CFR 689.6 - Investigations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Investigations. 689.6 Section 689.6 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION RESEARCH MISCONDUCT § 689.6 Investigations. (a) When an awardee institution or another Federal agency has promptly initiated its...

  18. 8 CFR 331.3 - Investigation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Investigation. 331.3 Section 331.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY NATIONALITY REGULATIONS ALIEN ENEMIES; NATURALIZATION... investigation of any alien enemy whose application for naturalization is pending upon declaration of war or...

  19. 8 CFR 331.3 - Investigation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Investigation. 331.3 Section 331.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY NATIONALITY REGULATIONS ALIEN ENEMIES; NATURALIZATION... investigation of any alien enemy whose application for naturalization is pending upon declaration of war or...

  20. 8 CFR 331.3 - Investigation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Investigation. 331.3 Section 331.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY NATIONALITY REGULATIONS ALIEN ENEMIES; NATURALIZATION... investigation of any alien enemy whose application for naturalization is pending upon declaration of war or...

  1. 8 CFR 331.3 - Investigation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Investigation. 331.3 Section 331.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY NATIONALITY REGULATIONS ALIEN ENEMIES; NATURALIZATION... investigation of any alien enemy whose application for naturalization is pending upon declaration of war or...

  2. 8 CFR 331.3 - Investigation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Investigation. 331.3 Section 331.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY NATIONALITY REGULATIONS ALIEN ENEMIES; NATURALIZATION... investigation of any alien enemy whose application for naturalization is pending upon declaration of war or...

  3. The Power of Investigative Calculus Projects

    ERIC Educational Resources Information Center

    Perrin, John Robert; Quinn, Robert J.

    2008-01-01

    This article describes investigative calculus projects in which students explore a question or problem of their own construction. Three exemplary pieces of student work are showcased. Investigative calculus projects are an excellent way to foster student understanding and interest in calculus. (Contains 4 figures.)

  4. ENGINEERING ASPECTS OF WATERBORNE DISEASE INVESTIGATIONS

    EPA Science Inventory

    As part of a disease outbreak investigation involving drinking water, an engineering investigation may be necessary to determine how or why the pathogen of concern was able to get to the consumer. In many of the US outbreaks, the survival of the pathogen was dependent on multiple...

  5. An Investigation of Double Bass Vibrato Characteristics

    ERIC Educational Resources Information Center

    Mick, James

    2015-01-01

    The purpose of this study was to investigate and describe various vibrato characteristics of university double bass students. The primary objectives were: (1) to describe vibrato rate and width for commonly used fingers in first, fourth, and thumb positions; (2) to investigate whether students initiate vibrato in an upward or downward direction;…

  6. 7 CFR 29.132 - Division investigations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Division investigations. 29.132 Section 29.132... REGULATIONS TOBACCO INSPECTION Regulations Miscellaneous § 29.132 Division investigations. An inspector, sampler, or weigher, when authorized by the Division, may of his own initiative, or upon the request of...

  7. Investigations in Life Science, Junior High.

    ERIC Educational Resources Information Center

    Stephenson, Robert L.

    Developed for teachers of junior high school science classes, this unit presents ten investigations on plant growth, animal life, pond life, and general science interests. These investigations are designed to accompany any popular life science textbooks, may be used to supplement a year-long course in life science, are intended as a springboard…

  8. The Locust Jump: An Integrated Laboratory Investigation

    ERIC Educational Resources Information Center

    Scott, Jon

    2005-01-01

    The locust is well known for its ability to jump large distances to avoid predation. This class sets out a series of investigations into the mechanisms underlying the jump enabling students to bring together information from biomechanics, muscle physiology, and anatomy. The nature of the investigation allows it to be undertaken at a number of…

  9. 18 CFR 808.12 - Investigative powers.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Investigative powers. 808.12 Section 808.12 Conservation of Power and Water Resources SUSQUEHANNA RIVER BASIN COMMISSION HEARINGS AND ENFORCEMENT ACTIONS Compliance and Enforcement § 808.12 Investigative powers. (a)...

  10. 18 CFR 808.12 - Investigative powers.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Investigative powers. 808.12 Section 808.12 Conservation of Power and Water Resources SUSQUEHANNA RIVER BASIN COMMISSION HEARINGS AND ENFORCEMENT ACTIONS Compliance and Enforcement § 808.12 Investigative powers. (a)...

  11. 18 CFR 808.12 - Investigative powers.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Investigative powers. 808.12 Section 808.12 Conservation of Power and Water Resources SUSQUEHANNA RIVER BASIN COMMISSION HEARINGS AND ENFORCEMENT ACTIONS Compliance and Enforcement § 808.12 Investigative powers. (a)...

  12. 18 CFR 808.12 - Investigative powers.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Investigative powers. 808.12 Section 808.12 Conservation of Power and Water Resources SUSQUEHANNA RIVER BASIN COMMISSION HEARINGS AND ENFORCEMENT ACTIONS Compliance and Enforcement § 808.12 Investigative powers. (a)...

  13. 32 CFR 776.84 - Ethics investigation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ethics investigation: (1) To request a hearing before the investigating officer (IO); (2) To inspect all... be assisted by counsel (see paragraph (c) of this section); (6) To challenge the IO for cause (such... available. (d) If a hearing is requested, the IO will conduct the hearing after reasonable notice to...

  14. 32 CFR 776.84 - Ethics investigation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ethics investigation: (1) To request a hearing before the investigating officer (IO); (2) To inspect all... be assisted by counsel (see paragraph (c) of this section); (6) To challenge the IO for cause (such... available. (d) If a hearing is requested, the IO will conduct the hearing after reasonable notice to...

  15. 32 CFR 776.84 - Ethics investigation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ethics investigation: (1) To request a hearing before the investigating officer (IO); (2) To inspect all... be assisted by counsel (see paragraph (c) of this section); (6) To challenge the IO for cause (such... available. (d) If a hearing is requested, the IO will conduct the hearing after reasonable notice to...

  16. 32 CFR 776.84 - Ethics investigation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ethics investigation: (1) To request a hearing before the investigating officer (IO); (2) To inspect all... be assisted by counsel (see paragraph (c) of this section); (6) To challenge the IO for cause (such... available. (d) If a hearing is requested, the IO will conduct the hearing after reasonable notice to...

  17. 12 CFR 308.503 - Investigations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Investigations. 308.503 Section 308.503 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.503 Investigations. (a) If...

  18. 12 CFR 308.503 - Investigations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Investigations. 308.503 Section 308.503 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.503 Investigations. (a) If...

  19. 12 CFR 308.503 - Investigations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Investigations. 308.503 Section 308.503 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.503 Investigations. (a) If...

  20. 12 CFR 308.503 - Investigations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 5 2012-01-01 2012-01-01 false Investigations. 308.503 Section 308.503 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.503 Investigations. (a) If...

  1. 12 CFR 308.503 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Investigations. 308.503 Section 308.503 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.503 Investigations. (a) If...

  2. 44 CFR 7.943 - Investigation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Investigation. 7.943 Section 7.943 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF...) FEMA will investigate complaints that are unresolved after mediation or are reopened because of...

  3. 37 CFR 11.22 - Disciplinary investigations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Disciplinary investigations. (a) The OED Director is authorized to investigate possible grounds for discipline... from any source suggesting possible grounds for discipline. Neither unwillingness nor neglect by a... concerning possible grounds for discipline of a practitioner may report the information or evidence to...

  4. 41 CFR 101-39.403 - Investigation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 101-39.403 Public Contracts and Property Management Federal Property Management Regulations System... MANAGEMENT SYSTEMS 39.4-Accidents and Claims § 101-39.403 Investigation. (a) Every accident involving a GSA Interagency Fleet Management System (IFMS) vehicle shall be investigated and a report furnished to the...

  5. 41 CFR 101-39.403 - Investigation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 101-39.403 Public Contracts and Property Management Federal Property Management Regulations System... MANAGEMENT SYSTEMS 39.4-Accidents and Claims § 101-39.403 Investigation. (a) Every accident involving a GSA Interagency Fleet Management System (IFMS) vehicle shall be investigated and a report furnished to the...

  6. 41 CFR 101-39.403 - Investigation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Section 101-39.403 Public Contracts and Property Management Federal Property Management Regulations System... MANAGEMENT SYSTEMS 39.4-Accidents and Claims § 101-39.403 Investigation. (a) Every accident involving a GSA Interagency Fleet Management System (IFMS) vehicle shall be investigated and a report furnished to the...

  7. 41 CFR 101-39.403 - Investigation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 101-39.403 Public Contracts and Property Management Federal Property Management Regulations System... MANAGEMENT SYSTEMS 39.4-Accidents and Claims § 101-39.403 Investigation. (a) Every accident involving a GSA Interagency Fleet Management System (IFMS) vehicle shall be investigated and a report furnished to the...

  8. 33 CFR 116.15 - Preliminary investigation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Investigation, to the Administrator, Bridge Administration Program. (b) The Preliminary Investigation Report will include a description of the nature and extent of the obstruction, the alterations to the bridge believed necessary to meet the reasonable needs of existing and future navigation, the type and volume...

  9. 33 CFR 116.20 - Detailed investigation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Bridge Programs determines that a Detailed Investigation should be conducted, the District Commander will initiate an investigation that addresses all of the pertinent data regarding the bridge, including... discuss: the obstructive character of the bridge in question; the impact of that bridge upon...

  10. 33 CFR 116.15 - Preliminary investigation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Investigation, to the Administrator, Office of Bridge Programs. (b) The Preliminary Investigation Report will include a description of the nature and extent of the obstruction, the alterations to the bridge believed necessary to meet the reasonable needs of existing and future navigation, the type and volume of...

  11. 33 CFR 116.20 - Detailed investigation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Bridge Programs determines that a Detailed Investigation should be conducted, the District Commander will initiate an investigation that addresses all of the pertinent data regarding the bridge, including... discuss: the obstructive character of the bridge in question; the impact of that bridge upon...

  12. 33 CFR 116.15 - Preliminary investigation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Investigation, to the Administrator, Office of Bridge Programs. (b) The Preliminary Investigation Report will include a description of the nature and extent of the obstruction, the alterations to the bridge believed necessary to meet the reasonable needs of existing and future navigation, the type and volume of...

  13. 33 CFR 116.20 - Detailed investigation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., Office of Bridge Programs determines that a Detailed Investigation should be conducted, the District Commander will initiate an investigation that addresses all of the pertinent data regarding the bridge... will discuss: the obstructive character of the bridge in question; the impact of that bridge...

  14. 33 CFR 116.15 - Preliminary investigation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Investigation, to the Administrator, Bridge Administration Program. (b) The Preliminary Investigation Report will include a description of the nature and extent of the obstruction, the alterations to the bridge believed necessary to meet the reasonable needs of existing and future navigation, the type and volume...

  15. 33 CFR 116.20 - Detailed investigation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., Office of Bridge Programs determines that a Detailed Investigation should be conducted, the District Commander will initiate an investigation that addresses all of the pertinent data regarding the bridge... will discuss: the obstructive character of the bridge in question; the impact of that bridge...

  16. 33 CFR 116.15 - Preliminary investigation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Investigation, to the Administrator, Office of Bridge Programs. (b) The Preliminary Investigation Report will include a description of the nature and extent of the obstruction, the alterations to the bridge believed necessary to meet the reasonable needs of existing and future navigation, the type and volume of...

  17. Cancer Cluster Investigation in a School District.

    ERIC Educational Resources Information Center

    Neuberger, John S.; Pierce, J. Thomas; Lai, Sue Min

    1997-01-01

    Investigated a possible cancer cluster among employees at one elementary school. Results of an industrial hygiene survey and health investigation found a marginally significant increase of risk for breast cancer among females who had worked for the school but no other excess in cancers. There were no significant employee exposures to carcinogens…

  18. 25 Low-Cost Biology Investigations.

    ERIC Educational Resources Information Center

    Beller, Joel

    This book is a compilation of biology labs that are safe, simple, dependable, economical, and diverse. Some of the 25 investigations contained within this book involve organisms that are free for the taking and returned to the environment unharmed following the investigations. Students gain experience in making observations, forming hypotheses,…

  19. Investigating Conscious Experience through the Beeper Project

    ERIC Educational Resources Information Center

    Punzo, Vincent A.; Miller, Emily

    2002-01-01

    The Experience Sampling Method (ESM; Larson & Csikszentmihalyi, 1983) is a means to investigate the subjective experiences of individuals as they go about their daily lives. Students from 2 Adolescent Psychology courses used the ESM in a required "beeper project." Student research teams investigated a typical week in the life of an adolescent by…

  20. 29 CFR 1985.104 - Investigation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Investigation. 1985.104 Section 1985.104 Labor Regulations... FINANCIAL PROTECTION ACT OF 2010 Complaints, Investigations, Findings, and Preliminary Orders § 1985.104... to present legal and factual arguments. The respondent must present this evidence within 10...

  1. Investigation of Outbreaks Complicated by Universal Exposure

    PubMed Central

    Bousema, Teun; Oliver, Isabel

    2012-01-01

    Outbreaks in which most or all persons were exposed to the same suspected source of infection, so-called universal exposure, are common. They represent a challenge for public health specialists because conducting analytical studies in such investigations is complicated by the absence of a nonexposed group. We describe different strategies that can support investigations of outbreaks with universal exposure. The value of descriptive epidemiology, extensive environmental investigation, and the hypothesis-generation phase cannot be overemphasized. An exposure that seems universal may in fact not be universal when additional aspects of the exposure are taken into account. Each exposure has unique characteristics that may not be captured when investigators rely on the tools readily at hand, such as standard questionnaires. We therefore encourage field epidemiologists to be creative and consider the use of alternative data sources or original techniques in their investigations of outbreaks with universal exposure. PMID:23092616

  2. Human Factors in Cabin Accident Investigations

    NASA Technical Reports Server (NTRS)

    Chute, Rebecca D.; Rosekind, Mark R. (Technical Monitor)

    1996-01-01

    Human factors has become an integral part of the accident investigation protocol. However, much of the investigative process remains focussed on the flight deck, airframe, and power plant systems. As a consequence, little data has been collected regarding the human factors issues within and involving the cabin during an accident. Therefore, the possibility exists that contributing factors that lie within that domain may be overlooked. The FAA Office of Accident Investigation is sponsoring a two-day workshop on cabin safety accident investigation. This course, within the workshop, will be of two hours duration and will explore relevant areas of human factors research. Specifically, the three areas of discussion are: Information transfer and resource management, fatigue and other physical stressors, and the human/machine interface. Integration of these areas will be accomplished by providing a suggested checklist of specific cabin-related human factors questions for investigators to probe following an accident.

  3. 32 CFR 637.5 - Off-post investigations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.5 Off-post investigations. (a... or personnel, the military police exercising area responsibility will request copies of the...

  4. 32 CFR 637.5 - Off-post investigations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.5 Off-post investigations. (a... or personnel, the military police exercising area responsibility will request copies of the...

  5. 32 CFR 637.5 - Off-post investigations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.5 Off-post investigations. (a... or personnel, the military police exercising area responsibility will request copies of the...

  6. 32 CFR 637.5 - Off-post investigations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.5 Off-post investigations. (a... or personnel, the military police exercising area responsibility will request copies of the...

  7. 32 CFR 637.5 - Off-post investigations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.5 Off-post investigations. (a... or personnel, the military police exercising area responsibility will request copies of the...

  8. 49 CFR 1503.203 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY ADMINISTRATIVE AND PROCEDURAL RULES INVESTIGATIVE AND ENFORCEMENT PROCEDURES... Chief Counsel, the Assistant Administrator for Security Operations, the Assistant Administrator...

  9. 48 CFR 2822.406-8 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 2822.406-8 Investigations. Pursuant to FAR 22.406-8(d), the contracting officer shall prepare and...

  10. 48 CFR 622.406-8 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 622.406-8 Investigations. (a) The chief of the contracting activity is responsible for conducting...

  11. Investigation of critical burning of fuel droplets

    NASA Technical Reports Server (NTRS)

    Faeth, G. M.

    1979-01-01

    The general problem of spray combustion was investigated. The combustion of bipropellent droplets; combustion of hydrozine fuels; and combustion of sprays were studied. A model was developed to predict mean velocities and temperatures in a combusting gas jet.

  12. Glassy materials investigated for nuclear reactor applications

    NASA Technical Reports Server (NTRS)

    Lynch, E. D.

    1968-01-01

    Studies determine the feasibility of preparing fuel-bearing glasses and glasses bearing neutron-absorbing materials for use as crystalline fuel and control rods for reactors. Properties investigated were devitrification resistance, urania solubility, and density.

  13. 21 CFR 812.25 - Investigational plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., ingredient, property, and principle of operation of the device and of each anticipated change in the device... chairpersons of all IRB's that have been or will be asked to review the investigation, and a certification...

  14. 21 CFR 812.25 - Investigational plan.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., ingredient, property, and principle of operation of the device and of each anticipated change in the device... chairpersons of all IRB's that have been or will be asked to review the investigation, and a certification...

  15. Investigative study of holographic recording materials development

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The potential of certain cis-trans isomers and doped LiNbO3 for the holographic read/write/erase memory application was investigated. The cis-trans work involved the photochemical investigation of a number of potential materials as well as specific molecular engineering efforts on alpha-methyl stilbene and its derivatives. These efforts resulted in an increase in the change in index of refraction, and thereby, in potential recording utility, of an order of magnitude. The work on LiNbO3 was directed toward a preliminary investigation of the dynamics of the writing process. Several samples and a variety of writing conditions were investigated. An unexpected and as yet unexplained improvement in material behavior with continued recycling was observed. In addition, some effort was devoted to an analysis of the physical conditions under which several current theories of the optical damage process are valid.

  16. Mathematical Investigations Using Logo: Part 1.

    ERIC Educational Resources Information Center

    Brown, Ken

    1986-01-01

    Describes investigations involving data acquisition and analysis using microcomputers running the LOGO programing language. Provides new primitives to add to LOGO to access information from the analog to digital converter of a BBC microcomputer, giving samples of student results. (JM)

  17. Deer Lodge Valley investigations, western Montana

    SciTech Connect

    Wideman, C.J.; Sonderegger, J.; Crase, E.; Peterson, J.; Ruscetta, C.A.

    1982-07-01

    A review of the geothermal investigations conducted in the Deer Lodge Valley of Western Montana is briefly presented. Maps of the generalized geology and Bouguer gravity and graphs of selected geothermal gradients and resistivity sounding profiles are presented. (MJF)

  18. 40 CFR 68.81 - Incident investigation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... investigation began; (3) A description of the incident; (4) The factors that contributed to the incident; and... job tasks are relevant to the incident findings including contract employees where applicable....

  19. McGee Ranch CPT investigation

    SciTech Connect

    Cassem, B.R.

    1993-06-15

    Applied Research Associated, Inc. (ARA), under contract to Argonne National Laboratory to perform work for Westinghouse Hanford Company (WHC), conducted Peizo Cone Penetration (P-CPT) Tests as part of an investigation of the fine-textured soils at the McGee Ranch Site. The purpose of the investigation was to characterize a potential borrow area for fine-textured soil materials that would be used to construct multi-layer closure covers on the Hanford Site. As part of the investigation, WHC conducted non auger-drill borings on the site during September 1992. ARA`s objective was to characterize the soils at the McGee Ranch site using the cone penetrometer and compare the findings with the lithologic characterization obtained from geologic boring logs. This report documents ARA`s site investigation efforts, test techniques, and analysis of the data for field work conducted April 14 and 15, 1993.

  20. SHERLOC: An Investigation for Mars 2020

    NASA Astrophysics Data System (ADS)

    Beegle, L. W.; Bhartia, R.; DeFlores, L.; Abbey, W.; Carrier, B.; Asher, S.; Burton, A.; Conrad, P.; Clegg, S.; Edgett, K. S.; Ehlmann, B.; Fries, M.; Hug, W.; Reid, R.; Kah, L.; Nealson, K.; Minitti, M.; Popp, J.; Langenhorst, F.; Orphan, V.; Sorbon, P.; Steele, A.; Tarcea, N.; Wanger, G.; Wiens, R.; Williford, K.; Yingst, R. A.

    2016-05-01

    The Scanning Habitable Environments with Raman and Luminescence for Organics and Chemicals (SHERLOC) investigation consists of a Deep UV (DUV) native fluorescence and resonance Raman spectrometer with MAHLI like imaging capabilities.

  1. Mathematical Investigations Using Logo. Part Two.

    ERIC Educational Resources Information Center

    Brown, Ken

    1986-01-01

    Programs (using Logo) developed by children to produce multiples, the Fibonacci series, and square numbers are presented, with graphical representations of functions introduced. Another investigation involves drawing a circle using turtle graphics. (MNS)

  2. 48 CFR 622.406-8 - Investigations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 622.406-8 Investigations. (a) The chief of the contracting activity is responsible for conducting...

  3. 48 CFR 622.406-8 - Investigations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 622.406-8 Investigations. (a) The chief of the contracting activity is responsible for conducting...

  4. 48 CFR 622.406-8 - Investigations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 622.406-8 Investigations. (a) The chief of the contracting activity is responsible for conducting...

  5. 42 CFR 457.925 - Preliminary investigation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS TO STATES Program Integrity § 457.925 Preliminary investigation. If the State agency receives a complaint of fraud or...

  6. 42 CFR 457.925 - Preliminary investigation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS TO STATES Program Integrity § 457.925 Preliminary investigation. If the State agency receives a complaint of fraud or...

  7. 42 CFR 457.925 - Preliminary investigation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS TO STATES Program Integrity § 457.925 Preliminary investigation. If the State agency receives a complaint of fraud or...

  8. Two-Phase Flow Separator Investigation

    NASA Video Gallery

    The goal of the Two-Phase Flow Separator investigation is to help increase understanding of how to separate gases and liquids in microgravity. Many systems on the space station contain both liquids...

  9. 40 CFR 68.81 - Incident investigation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... investigation began; (3) A description of the incident; (4) The factors that contributed to the incident; and... job tasks are relevant to the incident findings including contract employees where applicable....

  10. Investigations in Marine Chemistry: Tide Pool Ecology.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    Students investigated the salinity of tide pools at different levels in the intertidal zone. Data are analyzed collectively. Students graphed and discussed data. Included are suggestions for evaluation and further study. (Author)

  11. Geologic investigations of outer planets satellites

    NASA Technical Reports Server (NTRS)

    Strom, R. G.

    1984-01-01

    Four tests are examined: (1) investigation of volcanism on Io; Interim results of thermal and structural modeling of volcanism on Io are presented, (2) a study of the ancient heavily cratered regions on Ganymede, (3) a geologic comparison of the cratering record on Ganymede and Callisto, and (4) a geological and chemical investigation of internal resurfacing processes on the Saturnian satellites. Tasks 2, 3, and 4 utilize Voyager imaging data.

  12. Investigation of drug interactions with pinaverium bromide.

    PubMed

    Devred, C; Godeau, P; Guerot, C; Librez, P; Mougeot, G; Orsetti, A; Segrestaa, J M

    1986-01-01

    A series of studies was carried out at 6 centres to investigate possible drug interaction between the spasmolytic, pinaverium bromide, and cardiac glycosides, anticoagulants and hypoglycaemic agents given to patients as part of the long-term treatment of their condition. The results of clinical and laboratory investigations did not show any evidence of pinaverium bromide interfering with the action or activity of any of the drugs studied. PMID:3084176

  13. Internal compliance investigations can reduce government sanctions.

    PubMed

    Mustokoff, M M; Yecies, M S

    1997-10-01

    An effective corporate compliance program is facilitated by three essential elements: a well-qualified compliance officer; a policy of immediate investigation of every report of potential fraud and abuse; and clearly defined roles for both corporate and outside counsel in conducting the investigations. A government agency is less likely to exercise the full extent of its powers when these elements are in place and three is evidence of a sincere compliance effort.

  14. Investigation of laser polarized xenon magnetic resonance

    NASA Technical Reports Server (NTRS)

    Walsworth, Ronald L.

    1998-01-01

    Ground-based investigations of a new biomedical diagnostic technology: nuclear magnetic resonance of laser polarized noble gas are addressed. The specific research tasks discussed are: (1) Development of a large-scale noble gas polarization system; (2) biomedical investigations using laser polarized noble gas in conventional (high magnetic field) NMR systems; and (3) the development and application of a low magnetic field system for laser polarized noble gas NMR.

  15. The SIR-B science investigations plan

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Shuttle Imaging Radar-B (SIR-B) is the second synthetic aperture radar (SAR) to be flown on the National Aeronautics and Space Administration's Space Transportation System (Shuttle). It is the first spaceborne SAR to feature an antenna that allows acquisition of multiincidence angle imagery. An international team of scientists will use SIR-B to conduct investigations in a wide range of disciplines. The radar, the mission, and the investigations are described.

  16. Investigation of paramagnetic response of metallic epoxies

    NASA Technical Reports Server (NTRS)

    Ash, R. L.; Chegini, H.

    1986-01-01

    The paramagnetic properties of epoxies which were impregnated with metal ions were examined as the primary task in this research. A major conclusion was that the quality control of the epoxies was insufficient to permit reliable evaluation. Subsequently, a new set of specimens is being prepared. As an additional task, a new method is investigated for estimating heats of combustion for saturated hydrocarbons. The results of that investigation have shown that the empirical approach is a promising method for on-line measurements.

  17. Internal compliance investigations can reduce government sanctions.

    PubMed

    Mustokoff, M M; Yecies, M S

    1997-10-01

    An effective corporate compliance program is facilitated by three essential elements: a well-qualified compliance officer; a policy of immediate investigation of every report of potential fraud and abuse; and clearly defined roles for both corporate and outside counsel in conducting the investigations. A government agency is less likely to exercise the full extent of its powers when these elements are in place and three is evidence of a sincere compliance effort. PMID:10173966

  18. Tripod-BETA: Incident investigation and analysis

    SciTech Connect

    Doran, J.A.; Graaf, G.C. van der

    1996-12-31

    Tripod-BETA is a methodology for conducting an incident analysis in parallel with the investigation, supported by a PC based tool. Interaction between these two processes provides the investigators with confirmation of the relevance of their fact gathering and highlights avenues of investigation leading to latent failures. The benefit to the analysis process is that logical anomalies can be highlighted and resolved while The investigation is still active. Tripod-BETA focuses initially on the accident mechanism - the physical process of the accident - and uses it as a structure to identify the controls and defenses that should have been in place. For the incident to happen these controls and defenses either were missing or failed. The investigation then examines the immediate and latent failures behind each missing or failed defense, following the Tripod theory of accident causation. Tripod-BETA software provides the means to collect and assemble investigation facts and manipulate them on screen into a graphic representation of the event and its causes - an accident tree. The logic of the tree structure (labeling and connections) can be tested to ensure that it conforms to the concepts of the Hazard and Effects Management Process (HEMP) and the Tripod theory. When anomalies and omissions have been resolved, a draft accident report can be auto-generated for final editing using a word processing package.

  19. Police investigations: discretion denied yet undeniably exercised

    PubMed Central

    Belur, J.; Tilley, N.; Osrin, D.; Daruwalla, N.; Kumar, M.; Tiwari, V.

    2014-01-01

    Police investigations involve determining whether a crime has been committed, and if so what type of crime, who has committed it and whether there is the evidence to charge the perpetrators. Drawing on fieldwork in Delhi and Mumbai, this paper explores how police investigations unfolded in the specific context of women’s deaths by burning in India. In particular, it focuses on the use of discretion despite its denial by those exercising it. In India, there are distinctive statutes relating to women’s suspicious deaths, reflecting the widespread expectation that the bride’s family will pay a dowry to the groom’s family and the tensions to which this may on occasion give rise in the early years of a marriage. Often, there are conflicting claims influencing how the woman’s death is classified. These in turn affect police investigation. The nature and direction of police discretion in investigating women’s deaths by burning reflect in part the unique nature of the legislation and the particular sensitivities in relation to these types of death. They also highlight processes that are liable to be at work in any crime investigation. It was found that police officers exercised unacknowledged discretion at seven specific points in the investigative process, with potentially significant consequences for the achievement of just outcomes: first response, recording the victim’s ‘dying declaration’, inquest, registering of the ‘First Information Report’, collecting evidence, arrest and framing of the charges. PMID:26376482

  20. RCRA Facility Investigation/Remedial Investigation Report for the Grace Road Site (631-22G)

    SciTech Connect

    Palmer, E.

    1998-10-02

    This report summarizes the activities and documents the results of a Resource Conservation and Recovery Act Facility Investigation/Remedial Investigation conducted at Grace Road Site on the Savannah River Site near Aiken, South Carolina.

  1. 78 FR 27116 - Draft Guidance for Industry on Charging for Investigational Drugs Under an Investigational New...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... Investigational Drugs Under an Investigational New Drug Application--Questions and Answers; Availability AGENCY... under an investigational new drug (IND) application. FDA has received a number of questions about how it... Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51,...

  2. 77 FR 75439 - Guidances for Industry and Investigators on Safety Reporting Requirements for Investigational New...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-20

    ... Requirements for Investigational New Drug Applications and Bioavailability/Bioequivalence Studies, and a Small... ``Investigational New Drug Safety Reporting Requirements for Human Drug and Biological Products and Safety Reporting... investigational new drug applications (IND) and bioavailability (BA) and bioequivalence (BE) studies....

  3. Where Do I Start (Beginning the Investigation)?

    NASA Astrophysics Data System (ADS)

    Kornacki, Jeffrey L.

    No doubt some will open directly to this chapter, because your product is contaminated with an undesirable microbe, or perhaps you have been asked to do such an investigation for another company's facility not previously observed by you and naturally you want tips on how to find where the contaminant is getting into the product stream. This chapter takes the reader through the process of beginning the investigation including understanding the process including the production schedule and critically reviewing previously generated laboratory data. Understanding the critical control points and validity of their critical limits is also important. Scoping the extent of the problem is next. It is always a good idea for the factory to have a rigorously validated cleaning and sanitation procedure that provides a documented "sanitation breakpoint," which can be useful in the "scoping" process, although some contamination events may extend past these "break-points." Touring the facility is next wherein preliminary pre-selection of areas for future sampling can be done. Operational samples and observations in non-food contact areas can be taken at this time. Then the operations personnel need to be consulted and plans made for an appropriate amount of time to observe equipment break down for "post-operational" sampling and "pre-operational" investigational sampling. Hence the chapter further discusses preparing operations personnel for the disruptions that go along with these investigations and assembling the sampling team. The chapter concludes with a discussion of post-startup observations after an investigation and sampling.

  4. Cyber Forensics Ontology for Cyber Criminal Investigation

    NASA Astrophysics Data System (ADS)

    Park, Heum; Cho, Sunho; Kwon, Hyuk-Chul

    We developed Cyber Forensics Ontology for the criminal investigation in cyber space. Cyber crime is classified into cyber terror and general cyber crime, and those two classes are connected with each other. The investigation of cyber terror requires high technology, system environment and experts, and general cyber crime is connected with general crime by evidence from digital data and cyber space. Accordingly, it is difficult to determine relational crime types and collect evidence. Therefore, we considered the classifications of cyber crime, the collection of evidence in cyber space and the application of laws to cyber crime. In order to efficiently investigate cyber crime, it is necessary to integrate those concepts for each cyber crime-case. Thus, we constructed a cyber forensics domain ontology for criminal investigation in cyber space, according to the categories of cyber crime, laws, evidence and information of criminals. This ontology can be used in the process of investigating of cyber crime-cases, and for data mining of cyber crime; classification, clustering, association and detection of crime types, crime cases, evidences and criminals.

  5. Environmental investigations in China - Lessons learned

    SciTech Connect

    Scott, J.C.; Couldwell, C.

    1997-12-31

    Western manufacturing companies seeking to build or acquire manufacturing capacity in China will likely need to perform an environmental assessment or environmental investigation of an existing enterprise facility, or of a greenfield site for a new facility. The purpose of the environmental assessment or investigation is to assess and investigate the potential presence of hazardous contamination and the potential liabilities associated with a facility or site as a result of the past and present use of the property. Types of environmental investigations in China have included the following: Environmental site assessments (Phase 1); Environmental site investigations (Phase 2); Environmental impact assessments (EIA); Environmental pollution abatement plans (air, water); Institutional strengthening projects (lending institutions); and mine waste management (China National Non-Ferrous Metals Corporation). This article will examine the realities and logistics of performing environmental site assessments (ESAs) in China. It will provide a discussion of the following items: environmental concerns; standards used for ESAs environmental regulations; information sources for ESAs; drilling contractors for soil and groundwater sampling; materials for construction of monitoring wells; analytical laboratories; and work authorization and government documentation.

  6. Principal Investigator Views of the IRB System

    PubMed Central

    Whitney, Simon N.; Alcser, Kirsten; Schneider, Carl E.; McCullough, Laurence B.; McGuire, Amy L.; Volk, Robert J.

    2008-01-01

    We undertook a qualitative e-mail survey of federally-funded principal investigators of their views of the US human subjects protection system, intended to identify the range of investigator attitudes. This was an exploratory study with a 14% response rate. Twenty-eight principal investigators responded; their comments were analyzed to show underlying themes, which are here presented along with supporting quotations. There was consensus that it is important to protect human subjects from research abuse, but disagreement over how well the IRB system is functioning. Some researchers felt that the system is effective and serves its purpose well. Of those who support the system, some endorse its methods, purpose, and daily functioning, as they experience it, without reservation. Others, while expressing some frustration, feel that the purpose is important and their local IRB does its best to make a difficult system work well. Those investigators who were more harshly critical commented on multiple flaws in the system, including (1) consent forms that are inappropriate and incomprehensible, (2) an emphasis on minutiae, and (3) concern with protecting the institution more than research subjects. Respondents told us that the IRB system is a particular burden for research in neurology, emergency medical conditions, repositories, and social sciences in general; a more comprehensive study might identify other problematic areas. Significant concern was expressed about the cost, inefficiency, and irrationality of IRB review. The IRB system works well for some researchers, but our results indicate that other investigators feel the costs outweigh the benefits. PMID:18392146

  7. Emerging molecular methods for male infertility investigation.

    PubMed

    Benkhalifa, Moncef; Montjean, Debbie; Belloc, Stephanie; Dalleac, Alain; Ducasse, Michel; Boyer, Pierre; Merviel, Philippe; Copin, Henri

    2014-01-01

    Male factors account for approximately 50% of reproductive pathology. Different disorders, including urogenital and endocrine system development abnormalities, lead to testicular and gametogenesis defects. Parallely, studies have reported that somatic and germ cell genome decay are a major cause of male infertility. It has been shown that in somatic karyotype, there is a higher incidence of chromosomal aberrations in infertile men than neonatal population and significant chromosome Y microdeletion or specific gene alterations in affected spermatogenesis. Karyotyping and FISH application at somatic and germ cell levels are no longer sufficient to investigate the potential contribution of genome disorders on male infertility. A wide range of molecular methods are required for better understanding of male infertility causes. Molecular omes and omics techniques have become a great tool to investigate male infertility from chromosome to protein. This review reports different molecular tests and methods that can be offered for male infertility investigation.

  8. Investigation of organic adhesives for hybrid microcircuits

    NASA Technical Reports Server (NTRS)

    Perkins, K. L.; Licari, J. J.

    1975-01-01

    The properties of organic adhesives were investigated to acquire information for a guideline document regarding the selection of adhesives for use in high reliability hybrid microcircuits. Specifically, investigations were made of (1) alternate methods for determining the outgassing of cured adhesives, (2) effects of long term aging at 150 C on the electrical properties of conductive adhesives, (3) effects of shelf life age on adhesive characteristics, (4) bond strengths of electrically conductive adhesives on thick film gold metallization, (5) a copper filled adhesive, (6) effects of products outgassed from cured adhesives on device electrical parameters, (7) metal migration from electrically conductive adhesives, and (8) ionic content of electrically insulative adhesives. The tests performed during these investigations are described, and the results obtained are discussed.

  9. Columbia Accident Investigation Board Report. Volume 3

    NASA Technical Reports Server (NTRS)

    White, Donald J. (Editor); Goodman, Patrick A. (Editor); Reingold, Lester A. (Editor); Kirchhoff, Christopher M. (Editor); Simon, Ariel H. (Editor)

    2003-01-01

    This report describes the results of an investigative analysis performed by the Air Force Research Laboratory Sensors Directorate at th the specific request of the Defense Columbia Investigation Support Team (DCIST) who was supporting the Columbia Accident Investigation Board (CAIB). The work was performed during the period February 20, 2003 through 20 July 2003. An interim release of measurement findings was provided the CAIB on 24 April 2003, and the information was released in public testimony to the CAIB on May 6, 2003 at the Hilton Hotel, Houston, Texas. The overall assessment and conclusions of this report are consistent with the CAIB 6 May 2003 testimony, with one notable exception discussed in Section VI. This report has been reviewed by the AFRL/SN Flight Day Two DCIST appointed assessment team, and is hereby released to the CAIB and DCIST for final disposition.

  10. A European approach to clinical investigator training.

    PubMed

    Boeynaems, Jean-Marie; Canivet, Cindy; Chan, Anthony; Clarke, Mary J; Cornu, Catherine; Daemen, Esther; Demotes, Jacques; Nys, Katelijne De; Hirst, Barry; Hundt, Ferdinand; Kassai, Behrouz; Kerpel-Fronius, Sandor; Kiessig, Lucy; Klech, Heinrich; Kraehenbuhl, Jean-Pierre; Lafolie, Pierre; Lucht, Martin; Niese, Detlef; Pauli-Magnus, Christiane; Peters, Barbara; Schaltenbrand, Ralf; Stockis, Armel; Stykova, Martina; Verheus, Nicolette; Klingmann, Ingrid

    2013-01-01

    A better education and training of clinical investigators and their teams is one of the factors that could foster the development of clinical research in Europe, a key objective of the Innovative Medicines Initiative (IMI). PharmaTrain (an IMI programme on training in medicines development), and European Clinical Research Infrastructures Network (ECRIN) have joined forces to address this issue. An advisory group composed of representatives of universities, pharmaceutical companies and other organisations met four times between June 2011 and July 2012. This resulted in a position paper proposing a strategy to improve and harmonize clinical investigator training in Europe, and including a detailed syllabus and list of learning outcomes. Major recommendations are the establishment of minimal and mutually recognized certification requirement for investigators throughout the EU and the creation of a European platform to provide a suitable course and examination infrastructure. PMID:24058345

  11. Procedures for ground-water investigations

    SciTech Connect

    Not Available

    1989-09-01

    This manual was developed by the Pacific Northwest Laboratory (PNL) to document the procedures used to carry out and control the technical aspects of ground-water investigations at the PNL. Ground-water investigations are carried out to fulfill the requirements for the US Department of Energy (DOE) to meet the requirements of DOE Orders. Investigations are also performed for various clients to meet the requirements of the Resource Conservation and Recovery Act of 1976 (RCRA) and the Comprehensive Environmental Response, Compensation and Liability Act of 1980 (CERCLA). National standards including procedures published by the American Society for Testing and Materials (ASTM) and the US Geological Survey were utilized in developing the procedures contained in this manual.

  12. Investigation of Single Stage Axial Fans

    NASA Technical Reports Server (NTRS)

    Ruden, P.

    1944-01-01

    The following investigations are connected with experiments on fans carried out by the author in the Gouttingen Aerodynamic Laboratory within the framework of the preliminary experiments for the new Gouttingen wind-tunnel project. A fan rotor was developed which had very high efficiency at the design point corresponding to moderate pressure and which, in addition, could operate at a proportionally high pressure, rise. To establish the determining operating factors the author carried out extensive theoretical investigation in Hannover. In this it was necessary, to depart from the usual assumption of vanishing radial velocities. The calculations were substantially lightened by the introduction of diagrams. The, first part of the.report describes the theoretical investigations; the second, the experiments carried out at Gouttingen.

  13. New Zealand SIR-B science investigations

    NASA Technical Reports Server (NTRS)

    Collins, M. A.; Oliver, P. J.; Cochrane, G. R.; Cole, J.; Coombs, D. S.; Barnes, E. J.; Ching, N. P.; Bennets, R. L.; Stephens, P. H.; Laing, A. K.

    1984-01-01

    It is proposed that shuttle imaging radar (SIR) data be used to study unusual geological features of New Zealand. Particular attention is planned for geological faults. SIR-B imagery is to be compared with LANDSAT multispectral imagery. Three other investigations which are to use SIR data are discussed. An ocean eddy is to be studied from a correlation of SIR-B and advanced very high resolution radiometer imagery. Timber volume is to be assessed by determining the age and size of pine forests from SIR-B data. Soil moisture is to be investigated by comparing SIR-B data with simultaneous gravimetric data. Land cover in a region already subjected to intensive investigation using LANDSAT and aircraft scanner data is to be discriminated by SIR-B data.

  14. A European approach to clinical investigator training.

    PubMed

    Boeynaems, Jean-Marie; Canivet, Cindy; Chan, Anthony; Clarke, Mary J; Cornu, Catherine; Daemen, Esther; Demotes, Jacques; Nys, Katelijne De; Hirst, Barry; Hundt, Ferdinand; Kassai, Behrouz; Kerpel-Fronius, Sandor; Kiessig, Lucy; Klech, Heinrich; Kraehenbuhl, Jean-Pierre; Lafolie, Pierre; Lucht, Martin; Niese, Detlef; Pauli-Magnus, Christiane; Peters, Barbara; Schaltenbrand, Ralf; Stockis, Armel; Stykova, Martina; Verheus, Nicolette; Klingmann, Ingrid

    2013-09-09

    A better education and training of clinical investigators and their teams is one of the factors that could foster the development of clinical research in Europe, a key objective of the Innovative Medicines Initiative (IMI). PharmaTrain (an IMI programme on training in medicines development), and European Clinical Research Infrastructures Network (ECRIN) have joined forces to address this issue. An advisory group composed of representatives of universities, pharmaceutical companies and other organisations met four times between June 2011 and July 2012. This resulted in a position paper proposing a strategy to improve and harmonize clinical investigator training in Europe, and including a detailed syllabus and list of learning outcomes. Major recommendations are the establishment of minimal and mutually recognized certification requirement for investigators throughout the EU and the creation of a European platform to provide a suitable course and examination infrastructure.

  15. Wildlife health investigations: needs, challenges and recommendations.

    PubMed

    Ryser-Degiorgis, Marie-Pierre

    2013-11-04

    In a fast changing world with growing concerns about biodiversity loss and an increasing number of animal and human diseases emerging from wildlife, the need for effective wildlife health investigations including both surveillance and research is now widely recognized. However, procedures applicable to and knowledge acquired from studies related to domestic animal and human health can be on partly extrapolated to wildlife. This article identifies requirements and challenges inherent in wildlife health investigations, reviews important definitions and novel health investigation methods, and proposes tools and strategies for effective wildlife health surveillance programs. Impediments to wildlife health investigations are largely related to zoological, behavioral and ecological characteristics of wildlife populations and to limited access to investigation materials. These concerns should not be viewed as insurmountable but it is imperative that they are considered in study design, data analysis and result interpretation. It is particularly crucial to remember that health surveillance does not begin in the laboratory but in the fields. In this context, participatory approaches and mutual respect are essential. Furthermore, interdisciplinarity and open minds are necessary because a wide range of tools and knowledge from different fields need to be integrated in wildlife health surveillance and research. The identification of factors contributing to disease emergence requires the comparison of health and ecological data over time and among geographical regions. Finally, there is a need for the development and validation of diagnostic tests for wildlife species and for data on free-ranging population densities. Training of health professionals in wildlife diseases should also be improved. Overall, the article particularly emphasizes five needs of wildlife health investigations: communication and collaboration; use of synergies and triangulation approaches; investments

  16. Wildlife health investigations: needs, challenges and recommendations

    PubMed Central

    2013-01-01

    In a fast changing world with growing concerns about biodiversity loss and an increasing number of animal and human diseases emerging from wildlife, the need for effective wildlife health investigations including both surveillance and research is now widely recognized. However, procedures applicable to and knowledge acquired from studies related to domestic animal and human health can be on partly extrapolated to wildlife. This article identifies requirements and challenges inherent in wildlife health investigations, reviews important definitions and novel health investigation methods, and proposes tools and strategies for effective wildlife health surveillance programs. Impediments to wildlife health investigations are largely related to zoological, behavioral and ecological characteristics of wildlife populations and to limited access to investigation materials. These concerns should not be viewed as insurmountable but it is imperative that they are considered in study design, data analysis and result interpretation. It is particularly crucial to remember that health surveillance does not begin in the laboratory but in the fields. In this context, participatory approaches and mutual respect are essential. Furthermore, interdisciplinarity and open minds are necessary because a wide range of tools and knowledge from different fields need to be integrated in wildlife health surveillance and research. The identification of factors contributing to disease emergence requires the comparison of health and ecological data over time and among geographical regions. Finally, there is a need for the development and validation of diagnostic tests for wildlife species and for data on free-ranging population densities. Training of health professionals in wildlife diseases should also be improved. Overall, the article particularly emphasizes five needs of wildlife health investigations: communication and collaboration; use of synergies and triangulation approaches; investments

  17. Wildlife health investigations: needs, challenges and recommendations.

    PubMed

    Ryser-Degiorgis, Marie-Pierre

    2013-01-01

    In a fast changing world with growing concerns about biodiversity loss and an increasing number of animal and human diseases emerging from wildlife, the need for effective wildlife health investigations including both surveillance and research is now widely recognized. However, procedures applicable to and knowledge acquired from studies related to domestic animal and human health can be on partly extrapolated to wildlife. This article identifies requirements and challenges inherent in wildlife health investigations, reviews important definitions and novel health investigation methods, and proposes tools and strategies for effective wildlife health surveillance programs. Impediments to wildlife health investigations are largely related to zoological, behavioral and ecological characteristics of wildlife populations and to limited access to investigation materials. These concerns should not be viewed as insurmountable but it is imperative that they are considered in study design, data analysis and result interpretation. It is particularly crucial to remember that health surveillance does not begin in the laboratory but in the fields. In this context, participatory approaches and mutual respect are essential. Furthermore, interdisciplinarity and open minds are necessary because a wide range of tools and knowledge from different fields need to be integrated in wildlife health surveillance and research. The identification of factors contributing to disease emergence requires the comparison of health and ecological data over time and among geographical regions. Finally, there is a need for the development and validation of diagnostic tests for wildlife species and for data on free-ranging population densities. Training of health professionals in wildlife diseases should also be improved. Overall, the article particularly emphasizes five needs of wildlife health investigations: communication and collaboration; use of synergies and triangulation approaches; investments

  18. Results of the HESSI Test Mishap Investigation

    NASA Technical Reports Server (NTRS)

    Worth, Daniel B.; Phillips, Rodney N.; Kross, Dennis A. (Technical Monitor)

    2000-01-01

    On March 21, 2000, the High-Energy Solar Spectroscopic Imager (HESSI) spacecraft was subjected to a series of vibration tests at the Jet Propulsion Laboratory (JPL) as a part of its flight certification program. The structural qualification test, denoted as the sineburst test, subjected the spacecraft to a major overtest that resulted in significant structural damage to the spacecraft. The HESSI Test Mishap Investigation Board (MIB) was formed on March 24, 2000, in response to a NASA headquarters request. Board membership included experts from NASA and the University of California at Berkeley. This paper will present the investigation methods, findings, and lessons learned from the HESSI mishap.

  19. The Living With a Star Geospace Investigations

    NASA Technical Reports Server (NTRS)

    Spann, Jim; Kintner, Paul; Six, N. Frank (Technical Monitor)

    2002-01-01

    The Living With a Star Geospace Investigations is established to effectively address those phenomena the Geospace environment that directly affect life and society. The priority science questions focus on two broad areas: (1) ionospheric variability, especially at mid-latitudes, that affects navigation and communications and (2) the source, acceleration mechanisms, and sinks of the radiation belts that degrade satellite lifetimes, produce surface charging, and threaten manned space flight. Candidate missions to address these science foci will be presented as well as possible additional investigations and experiments that would enable an understanding of the Geospace at the system level.

  20. Radiotracer investigation in a glass production unit.

    PubMed

    Pant, H J; Goswami, Sunil; Biswal, Jayashree; Samantaray, J S; Sharma, V K; Singhal, Sorabh

    2016-10-01

    A radiotracer investigation was carried out in a glass production unit in a glass industry. Lanthanum-140 as lanthanium oxide mixed with silica was used as a radiotracer to trace the molten glass in various sections of the unit. Residence time distributions of molten glass were measured and analyzed to identify the flow abnormities. The flow parameters such as breakthrough time, mean residence time, homogenization time, dead volume and flow patterns in different sections of the unit were obtained from the measured RTD data. The results of the investigation were used to improve and optimize the operation of the glass production unit. PMID:27474905