Sample records for airport security checkpoints

  1. Manufacturing Accomplices: ICT Use in Securing the Safety State at Airports

    NASA Astrophysics Data System (ADS)

    Østerlie, Thomas; Asak, Ole Martin; Pettersen, Ole Georg; Tronhus, Håvard

    Based on a study of ICT use at an airport security checkpoint, this paper explores a possible explanation to the paradox that travelers find existing airport security measures inadequate while at the same time believing air travel to be sufficiently secure. We pursue this explanation by showing that, for the security checkpoint to function properly in relation to the overall function of the airport, travelers have to be enrolled in a particular program of action. They are then locked into this program through sanctions. Travelers are forced into participating in a system many of them find ethically and morally objectionable. Yet, active participation makes it difficult for them to object to the moral and ethical issues of their actions without damning themselves. Our explanation of the security paradox is, therefore, that while travelers remain critical of airport security, they avoid damning themselves by criticizing the system in terms of its own logic. They have been made accomplices.

  2. Airport Viz - a 3D Tool to Enhance Security Operations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koch, Daniel B

    2006-01-01

    In the summer of 2000, the National Safe Skies Alliance (NSSA) awarded a project to the Applied Visualization Center (AVC) at the University of Tennessee, Knoxville (UTK) to develop a 3D computer tool to assist the Federal Aviation Administration security group, now the Transportation Security Administration (TSA), in evaluating new equipment and procedures to improve airport checkpoint security. A preliminary tool was demonstrated at the 2001 International Aviation Security Technology Symposium. Since then, the AVC went on to construct numerous detection equipment models as well as models of several airports. Airport Viz has been distributed by the NSSA to amore » number of airports around the country which are able to incorporate their own CAD models into the software due to its unique open architecture. It provides a checkpoint design and passenger flow simulation function, a layout design and simulation tool for checked baggage and cargo screening, and a means to assist in the vulnerability assessment of airport access points for pedestrians and vehicles.« less

  3. Detection of total knee prostheses at airport security checkpoints.

    PubMed

    Naziri, Qais; Johnson, Aaron J; Hooper, Hasan A; Sana, Said H; Mont, Michael A

    2012-06-01

    Airport security screening measures have changed substantially during the past decade, but few reports have examined how this affects patients who have undergone knee arthroplasties. The purpose of this study was to characterize the efficacy of airport metal detection of total knee prostheses, the delays faced, any inconvenience this may have caused, and the role of implant identification cards. Ninety-seven total knee arthroplasty recipients reported passing through an airport metal detector, with 70 triggering the alarm a mean of 3 times (range, 1-36). The presence of a single-knee prosthesis triggered airport security alarms more than 83% of the time and increased patient inconvenience. Patients should be informed about this chance and be prepared to present documentation of their prosthesis. Copyright © 2012 Elsevier Inc. All rights reserved.

  4. Detection of Total Knee Arthroplasties at Airport Security Checkpoints: How Do Updated Security Measures Affect Patients?

    PubMed

    Issa, Kimona; Pierce, Todd P; Gwam, Chukwuweieke; Goljan, Peter; Festa, Anthony; Scillia, Anthony J; Mont, Michael A

    2017-07-01

    Airport security measures continue to be updated with the incorporation of the new body scanners and automatic target recognition software. The purpose of this study was analyze the incidence of: (1) triggering the security alarm; (2) extra security searches; (3) perceived inconvenience; and (4) presence of other surgical hardware in those who underwent total knee arthroplasty (TKA) and passed through airport security. A questionnaire was given to 125 consecutive patients with a TKA. Those who passed through airport security after January 2014 were considered for inclusion. A questionnaire was administered that addressed the number of encounters with airport security, metal detector activation, additional screening procedures, and perceived inconvenience. Out of the 125 patients, 53 met inclusion criteria. Out of the 53 patients, 20 (38%) reported that their prosthesis triggered a metal detector. Out of the 20 patients, 8 (40%) who reported triggering of metal detectors also reported the presence of surgical hardware elsewhere in the body. Eighteen of the 53 patients (34%) believed having a TKA was inconvenient for airplane travel. Compared with the historical cohort, alarms were triggered in 70 of 97 patients ( p  = 0.0001) and 50 of 97 reported inconvenience when traveling ( n  = 50 of 97 patients; p  = 0.04). The incidences of those who underwent TKA triggering alarms and perceiving inconvenience when passing through airport security have decreased from previously published studies. This is most likely due to the recent updates and modifications to screening. As these security measures are modified and implant designs continue to evolve, this is an area of investigation that should continue. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  5. Identifying security checkpoints locations to protect the major U.S. urban areas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cuellar-Hengartner, Leticia; Watkins, Daniel; Kubicek, Deborah A.

    Transit networks are integral to the economy and to society, but at the same time they could allow terrorists to transport weapons of mass destruction into any city. Road networks are especially vulnerable, because they lack natural checkpoints unlike air networks that have security measures in place at all major airports. One approach to mitigate this risk is ensuring that every road route passes through at least one security checkpoint. Using the Ford-Fulkerson maximum-flow algorithm, we generate a minimum set of checkpoint locations within a ring-shaped buffer area surrounding the 50 largest US urban areas. We study how the numbermore » of checkpoints changes as we increase the buffer width to perform a cost-benefit analysis and to identify groups of cities that behave similarly. The set of required checkpoints is surprisingly small (10-124) despite the hundreds of thousands of road arcs in those areas, making it feasible to protect all major cities.« less

  6. Identifying security checkpoints locations to protect the major U.S. urban areas

    DOE PAGES

    Cuellar-Hengartner, Leticia; Watkins, Daniel; Kubicek, Deborah A.; ...

    2015-09-01

    Transit networks are integral to the economy and to society, but at the same time they could allow terrorists to transport weapons of mass destruction into any city. Road networks are especially vulnerable, because they lack natural checkpoints unlike air networks that have security measures in place at all major airports. One approach to mitigate this risk is ensuring that every road route passes through at least one security checkpoint. Using the Ford-Fulkerson maximum-flow algorithm, we generate a minimum set of checkpoint locations within a ring-shaped buffer area surrounding the 50 largest US urban areas. We study how the numbermore » of checkpoints changes as we increase the buffer width to perform a cost-benefit analysis and to identify groups of cities that behave similarly. The set of required checkpoints is surprisingly small (10-124) despite the hundreds of thousands of road arcs in those areas, making it feasible to protect all major cities.« less

  7. Detection of total hip arthroplasties at airport security checkpoints - how do updated security measures affect patients?

    PubMed

    Issa, Kimona; Pierce, Todd P; Gwam, Chukwuweieke; Festa, Anthony; Scillia, Anthony J; Mont, Michael A

    2018-03-01

    There have been historical reports on the experiences of patients with total hip arthroplasty (THA) passing through standard metal detectors at airports. The purpose of this study was to analyse those who had recently passed through airport security and the incidence of: (i) triggering of the alarm; (ii) extra security searches; and (iii) perceived inconvenience. A questionnaire was given to 125 patients with a THA during a follow-up appointment. Those who had passed through airport security after January 2014 met inclusion criteria. A survey was administered that addressed the number of encounters with airport security, frequency of metal detector activation, additional screening procedures utilised, whether security officials required prosthesis documentation, and perceived inconvenience. 51 patients met inclusion criteria. 10 patients (20%) reported triggered security scanners. 4 of the 10 patients stated they had surgical hardware elsewhere in the body. 13 of the 51 patients (25%) believed that having their THA increased the inconvenience of traveling. This is different from the historical cohort with standard metal detectors which patients reported a greater incidence of alarm triggering (n = 120 of 143; p = 0.0001) and perceived inconvenience (n = 99 of 143; p = 0.0001). The percentage of patients who have THA triggering security alarms has decreased. Furthermore, the number of patients who feel that their prosthesis caused traveling inconvenience has decreased. We feel that this decrease in alarms triggered and improved perceptions about inconvenience are related to the increased usage of new technology.

  8. Detection of total hip prostheses at airport security checkpoints: how has heightened security affected patients?

    PubMed

    Johnson, Aaron J; Naziri, Qais; Hooper, Hasan A; Mont, Michael A

    2012-04-04

    The sensitivity of airport security screening measures has increased substantially during the past decade, but few reports have examined how this affects patients who have undergone hip arthroplasty. The purpose of this study was to determine the experiences of patients who had hip prostheses and who passed through airport security screenings. A consecutive series of 250 patients who presented to the office of a high-volume surgeon were asked whether they had had a hip prosthesis for at least one year and, if so, whether they had flown on a commercial airline within the past year. Patients who responded affirmatively to both questions were asked to complete a written survey that included questions about which joint(s) had been replaced, the number of encounters with airport security, the frequency and location of metal detector activation, any additional screening procedures that were utilized, whether security officials requested documentation regarding the prosthesis, the degree of inconvenience, and other relevant information. Of the 143 patients with hip replacements who traveled by air, 120 (84%) reported triggering the alarm and required wanding with a handheld detector. Twenty-five of these patients reported subsequently having to undergo further inspection, including additional wanding, being patted down, and in two cases having to undress in a private room to show the incision. Ninety-nine (69%) of the 143 patients reported that the prosthetic joint caused an inconvenience while traveling. This study provides interesting and critical information that allows physicians to understand the real-world implications of implanted orthopaedic devices for patients who are traveling where there has been heightened security since September 11, 2001. Patients should be counseled that they should expect delays and be prepared for such inconveniences, but that these are often only momentary. This information could relieve some anxiety and concerns that patients may have

  9. From sniffer dogs to emerging sniffer devices for airport security: an opportunity to rethink privacy implications?

    PubMed

    Bonfanti, Matteo E

    2014-09-01

    Dogs are known for their incredible ability to detect odours, extracting them from a "complex" environment and recognising them. This makes sniffer dogs precious assets in a broad variety of security applications. However, their use is subject to some intrinsic restrictions. Dogs can only be trained to a limited set of applications, get tired after a relatively short period, and thus require a high turnover. This has sparked a drive over the past decade to develop artificial sniffer devices-generally known as "chemical sniffers" or "electronic noses"-able to complement and possibly replace dogs for some security applications. Such devices have been already deployed, or are intended to be deployed, at borders, airports and other critical installation security checkpoints. Similarly to dogs, they are adopted for detecting residual traces that indicate either the presence of, or recent contact with, substances like drugs and explosives. It goes without saying that, as with sniffer dogs, the use of artificial sniffer devices raises many sensitive issues. Adopting an ethical and legal perspective, the present paper discusses the privacy and data protection implications of the possible deployment of a hand-held body scanning sniffer for screening passengers at EU airport security checkpoints.

  10. 49 CFR 1542.113 - Airport tenant security programs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Airport tenant security programs. 1542.113 Section... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Airport Security Program § 1542.113 Airport tenant security programs. (a) TSA may approve an airport tenant...

  11. 49 CFR 1542.113 - Airport tenant security programs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Airport tenant security programs. 1542.113 Section... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Airport Security Program § 1542.113 Airport tenant security programs. (a) TSA may approve an airport tenant...

  12. 49 CFR 1542.113 - Airport tenant security programs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Airport tenant security programs. 1542.113 Section... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Airport Security Program § 1542.113 Airport tenant security programs. (a) TSA may approve an airport tenant...

  13. 49 CFR 1542.113 - Airport tenant security programs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Airport tenant security programs. 1542.113 Section... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Airport Security Program § 1542.113 Airport tenant security programs. (a) TSA may approve an airport tenant...

  14. 49 CFR 1542.113 - Airport tenant security programs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Airport tenant security programs. 1542.113 Section... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Airport Security Program § 1542.113 Airport tenant security programs. (a) TSA may approve an airport tenant...

  15. Transportation Security: Issues for the 111th Congress

    DTIC Science & Technology

    2009-05-15

    results of covert testing of airport security checkpoints demonstrating deficiencies in detecting improvised explosives and incendiary devices...34 A key issue in the debate over aviation security immediately following September 11, 2001, was whether airport security screeners should be...intentional wrongdoing on the part of airport security screeners, whether they be federal or private. Nonetheless, while the pilot program airports

  16. Optimization of airport security lanes

    NASA Astrophysics Data System (ADS)

    Chen, Lin

    2018-05-01

    Current airport security management system is widely implemented all around the world to ensure the safety of passengers, but it might not be an optimum one. This paper aims to seek a better security system, which can maximize security while minimize inconvenience to passengers. Firstly, we apply Petri net model to analyze the steps where the main bottlenecks lie. Based on average tokens and time transition, the most time-consuming steps of security process can be found, including inspection of passengers' identification and documents, preparing belongings to be scanned and the process for retrieving belongings back. Then, we develop a queuing model to figure out factors affecting those time-consuming steps. As for future improvement, the effective measures which can be taken include transferring current system as single-queuing and multi-served, intelligently predicting the number of security checkpoints supposed to be opened, building up green biological convenient lanes. Furthermore, to test the theoretical results, we apply some data to stimulate the model. And the stimulation results are consistent with what we have got through modeling. Finally, we apply our queuing model to a multi-cultural background. The result suggests that by quantifying and modifying the variance in wait time, the model can be applied to individuals with various habits customs and habits. Generally speaking, our paper considers multiple affecting factors, employs several models and does plenty of calculations, which is practical and reliable for handling in reality. In addition, with more precise data available, we can further test and improve our models.

  17. Economic Aspects of Airport Security Measures

    DTIC Science & Technology

    1999-06-01

    Airport security measures use very expensive equipment, and may keep passengers in line for several minutes. The time passengers spend in those lines...can add up, and must be understood as time opportunity cost. In the 1970s, several airport security measures were adopted to help stop aircraft...associated with airport security measures. He concluded that the costs of the adopted measures were very high. While Landes concentrated on the

  18. Giving radioiodine? Think about airport security alarms.

    PubMed

    Kaniuka-Jakubowska, S; Lewczuk, A; Mizan-Gross, K; Obołończyk, L; Lass, P; Sworczak, K

    2012-01-01

    An increased sensitivity of airport detectors, a growing number of isotopic tests, and globalization of the society have raised a number of false positive radioactive alarms at airports and public places. This paper presents two new cases of patients who triggered airport security alarms after receiving 740MBq of (131)I for non-toxic goitre and attempts to compare surprisingly limited literature concerning this problem. A 57-year-old man triggered a security alarm at three different airports on the 17th, 28th, and 31st day after radioiodine exposure. Interestingly enough, in the meantime, on the 18th and 22nd day, no radiation was detected in him at the airport where he was twice detained as a source of radiation later on. The second case presents a 45-year-old woman who activated security alarm detectors while crossing a border on her coach trip 28 days after radioiodine administration. Copyright © 2011 Elsevier España, S.L. and SEMNIM. All rights reserved.

  19. Aviation security : vulnerabilities still exist in the aviation security system

    DOT National Transportation Integrated Search

    2000-04-06

    The testimony today discusses the Federal Aviation Administration's (FAA) efforts to implement and improve security in two key areas: air traffic control computer systems and airport passenger screening checkpoints. Computer systems-and the informati...

  20. A novel wireless local positioning system for airport (indoor) security

    NASA Astrophysics Data System (ADS)

    Zekavat, Seyed A.; Tong, Hui; Tan, Jindong

    2004-09-01

    A novel wireless local positioning system (WLPS) for airport (or indoor) security is introduced. This system is used by airport (indoor) security guards to locate all of, or a group of airport employees or passengers within the airport area. WLPS consists of two main parts: (1) a base station that is carried by security personnel; hence, introducing dynamic base station (DBS), and (2) a transponder (TRX) that is mounted on all people (including security personnel) present at the airport; thus, introducing them as active targets. In this paper, we (a) draw a futuristic view of the airport security systems, and the flow of information at the airports, (b) investigate the techniques of extending WLPS coverage area beyond the line-of-sight (LoS), and (c) study the performance of this system via standard transceivers, and direct sequence code division multiple access (DS-CDMA) systems with and without antenna arrays and conventional beamforming (BF).

  1. Surveillance of ground vehicles for airport security

    NASA Astrophysics Data System (ADS)

    Blasch, Erik; Wang, Zhonghai; Shen, Dan; Ling, Haibin; Chen, Genshe

    2014-06-01

    Future surveillance systems will work in complex and cluttered environments which require systems engineering solutions for such applications such as airport ground surface management. In this paper, we highlight the use of a L1 video tracker for monitoring activities at an airport. We present methods of information fusion, entity detection, and activity analysis using airport videos for runway detection and airport terminal events. For coordinated airport security, automated ground surveillance enhances efficient and safe maneuvers for aircraft, unmanned air vehicles (UAVs) and unmanned ground vehicles (UGVs) operating within airport environments.

  2. The Need for an Implant Identification Card at Airport Security Check

    PubMed Central

    Kosuge, Dennis; MacDowell, Andrew

    2017-01-01

    Background Joint replacement surgery is having an increasing demand as national healthcare systems confront an ever ageing population. Surgical complications associated with lower limb arthroplasty are well known but less investigation has been performed examining its effect on air travel, more specifically, unwanted and significant inconvenience caused to travelers going through airport security. Methods In lower limb arthroplasty clinics, 50 patients who met our selection criteria were given questionnaires. Ten airport security officers from 4 international airports (London Stansted, London Gatwick, London Heathrow, and Amsterdam Schiphol International Airport) were also given a separate questionnaire. The opinion of the Civil Aviation Authority was also sought. Results All 50 patients (mean age, 70.4 years; range, 55 to 84 years) who were presenting in lower limb arthroplasty clinics and who met our selection criteria volunteered to enter the study. Twenty-eight of these patients were female (mean age, 69.1 years; range, 55 to 84 years) and 22 were male (mean age, 71.2 years; range, 58 to 81 years). Of the patients, 14% stated that their joint replacements did not set off the airport security alarm. Responses were received from 10 airport security officers as well. Six airport security officers were male and 4 were female. All of the airport officers were aware of some form of implant identification card with 90% stating that these were useful to them at airport security. Eight-four percent of the patients stated that an implant identification card outlining what joint replacement they possessed and when this had been done would be very useful. Sixteen percent of the patients did not think a card would be beneficial since all of them had set off the airport alarm system only once or less in their lifetime. Conclusions It is the opinion of airport security officers and patients that joint replacement implant identification cards streamline airport security checks

  3. The Need for an Implant Identification Card at Airport Security Check.

    PubMed

    Ali, Erden; Kosuge, Dennis; MacDowell, Andrew

    2017-06-01

    Joint replacement surgery is having an increasing demand as national healthcare systems confront an ever ageing population. Surgical complications associated with lower limb arthroplasty are well known but less investigation has been performed examining its effect on air travel, more specifically, unwanted and significant inconvenience caused to travelers going through airport security. In lower limb arthroplasty clinics, 50 patients who met our selection criteria were given questionnaires. Ten airport security officers from 4 international airports (London Stansted, London Gatwick, London Heathrow, and Amsterdam Schiphol International Airport) were also given a separate questionnaire. The opinion of the Civil Aviation Authority was also sought. All 50 patients (mean age, 70.4 years; range, 55 to 84 years) who were presenting in lower limb arthroplasty clinics and who met our selection criteria volunteered to enter the study. Twenty-eight of these patients were female (mean age, 69.1 years; range, 55 to 84 years) and 22 were male (mean age, 71.2 years; range, 58 to 81 years). Of the patients, 14% stated that their joint replacements did not set off the airport security alarm. Responses were received from 10 airport security officers as well. Six airport security officers were male and 4 were female. All of the airport officers were aware of some form of implant identification card with 90% stating that these were useful to them at airport security. Eight-four percent of the patients stated that an implant identification card outlining what joint replacement they possessed and when this had been done would be very useful. Sixteen percent of the patients did not think a card would be beneficial since all of them had set off the airport alarm system only once or less in their lifetime. It is the opinion of airport security officers and patients that joint replacement implant identification cards streamline airport security checks and decrease the need for more

  4. Near-Term Options for Improving Security at Los Angeles International Airport

    DTIC Science & Technology

    2004-09-26

    the Transportation Security Administration (TSA), the Los Angeles Police Department ( LAPD ), and LAX to make sure the list was reasonable...World Airports; the Transportation Security Agency; the Los Angeles International Airport Police Department ; the Los Angeles Police Department ; the Los ...Airports. iii PREFACE This document assesses near-term security

  5. 49 CFR 1542.3 - Airport security coordinator.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the airport operator's primary and immediate contact for security-related activities and... frequency all security-related functions to ensure that all are effective and in compliance with this part... for any instance of non-compliance with this part, its security program, and applicable Security...

  6. 49 CFR 1542.3 - Airport security coordinator.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the airport operator's primary and immediate contact for security-related activities and... frequency all security-related functions to ensure that all are effective and in compliance with this part... for any instance of non-compliance with this part, its security program, and applicable Security...

  7. 49 CFR 1542.3 - Airport security coordinator.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... the airport operator's primary and immediate contact for security-related activities and... frequency all security-related functions to ensure that all are effective and in compliance with this part... for any instance of non-compliance with this part, its security program, and applicable Security...

  8. 49 CFR 1542.3 - Airport security coordinator.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the airport operator's primary and immediate contact for security-related activities and... frequency all security-related functions to ensure that all are effective and in compliance with this part... for any instance of non-compliance with this part, its security program, and applicable Security...

  9. 49 CFR 1542.3 - Airport security coordinator.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the airport operator's primary and immediate contact for security-related activities and... frequency all security-related functions to ensure that all are effective and in compliance with this part... for any instance of non-compliance with this part, its security program, and applicable Security...

  10. The systems approach to airport security: The FAA (Federal Aviation Administration)/BWI (Baltimore-Washington International) Airport demonstration project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Caskey, D.L.; Olascoaga, M.T.

    1990-01-01

    Sandia National Laboratories has been involved in designing, installing and evaluating security systems for various applications during the past 15 years. A systems approach to security that evolved from this experience was applied to aviation security for the Federal Aviation Administration. A general systems study of aviation security in the United States was concluded in 1987. One result of the study was a recommendation that an enhanced security system concept designed to meet specified objectives be demonstrated at an operational airport. Baltimore-Washington International Airport was selected as the site for the demonstration project which began in 1988 and will bemore » completed in 1992. This article introduced the systems approach to airport security and discussed its application at Baltimore-Washington International Airport. Examples of design features that could be included in an enhanced security concept also were presented, including details of the proposed Ramps Area Intrusion Detection System (RAIDS).« less

  11. Measuring Security Effectiveness and Efficiency at U.S. Commercial Airports

    DTIC Science & Technology

    2013-03-01

    formative program evaluation and policy analysis to investigate current airport security programs. It identifies innovative public administration and...policy-analysis tools that could provide potential benefits to airport security . These tools will complement the System Based Risk Management framework if

  12. 19 CFR Appendix A to Part 113 - Airport Customs Security Area Bond

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Airport Customs Security Area Bond A Appendix A to... OF THE TREASURY CUSTOMS BONDS Pt. 113, App. A Appendix A to Part 113—Airport Customs Security Area Bond Airport Customs Security Area Bond (name of principal) of and (name of surety) of are held and...

  13. 19 CFR Appendix A to Part 113 - Airport Customs Security Area Bond

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Airport Customs Security Area Bond A Appendix A to... OF THE TREASURY CUSTOMS BONDS Pt. 113, App. A Appendix A to Part 113—Airport Customs Security Area Bond Airport Customs Security Area Bond (name of principal) of and (name of surety) of are held and...

  14. 19 CFR Appendix A to Part 113 - Airport Customs Security Area Bond

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Airport Customs Security Area Bond A Appendix A to... OF THE TREASURY CUSTOMS BONDS Pt. 113, App. A Appendix A to Part 113—Airport Customs Security Area Bond Airport Customs Security Area Bond (name of principal) of and (name of surety) of are held and...

  15. 19 CFR Appendix A to Part 113 - Airport Customs Security Area Bond

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Airport Customs Security Area Bond A Appendix A to... OF THE TREASURY CUSTOMS BONDS Pt. 113, App. A Appendix A to Part 113—Airport Customs Security Area Bond Airport Customs Security Area Bond (name of principal) of and (name of surety) of are held and...

  16. 19 CFR Appendix A to Part 113 - Airport Customs Security Area Bond

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Airport Customs Security Area Bond A Appendix A to... OF THE TREASURY CUSTOMS BONDS Pt. 113, App. A Appendix A to Part 113—Airport Customs Security Area Bond Airport Customs Security Area Bond (name of principal) of and (name of surety) of are held and...

  17. What Practices in Airport Security Should the United States Implement at Commercial Airports in Light of the Events of September 11, 2001?

    DTIC Science & Technology

    2002-06-01

    NAVAL POSTGRADUATE SCHOOL Monterey, California THESIS WHAT PRACTICES IN AIRPORT SECURITY SHOULD THE UNITED STATES IMPLEMENT AT...COVERED Master’s Thesis 4. TITLE AND SUBTITLE What Practices in Airport Security Should the United States Implement at Commercial...complacency and conflicts of interest. 14. SUBJECT TERMS Airport Security , Aviation Security Systems, Terrorism, Hijacking

  18. 76 FR 67019 - Tenth Meeting: RTCA Special Committee 224, Airport Security Access Control

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... 224, Airport Security Access Control AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Notice of RTCA Special Committee 224, Airport Security Access Control. SUMMARY: The... (Pub. L. 92-463, 5 U.S.C., App.), notice is hereby given for a Special Committee 224, Airport Security...

  19. AVIATION SECURITY: FAA’s Actions to Study Responsibilities and Funding for Airport Security and to Certify Screening Companies

    DTIC Science & Technology

    1999-02-01

    Actions to Study Responsibilities and Funding for Airport Security and to Certify Screening Companies DISTRIBUTION STATEMENT A Approved for...local law enforcement support relating to air carrier and airport security measures. The funding of the security operations is divided among FAA, the...generally agreed with the current division of airport security responsibilities. These officials stated that the continuity of screening would be

  20. Airport security inspection process model and optimization based on GSPN

    NASA Astrophysics Data System (ADS)

    Mao, Shuainan

    2018-04-01

    Aiming at the efficiency of airport security inspection process, Generalized Stochastic Petri Net is used to establish the security inspection process model. The model is used to analyze the bottleneck problem of airport security inspection process. The solution to the bottleneck is given, which can significantly improve the efficiency and reduce the waiting time by adding the place for people to remove their clothes and the X-ray detector.

  1. 75 FR 80886 - Third Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ... 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems. DATES: The meeting will be held January 13, 2011...

  2. 78 FR 16757 - Twentieth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security... meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  3. 77 FR 64838 - Sixteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security... meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  4. 75 FR 61819 - First Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ... 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems. DATES: The meeting will be held November 2, 2010...

  5. 75 FR 71790 - Second Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... Committee 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems. DATES: The meeting will be held December 9, 2010...

  6. 76 FR 9632 - Fifth Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-18

    ... 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems. DATES: The meeting will be held March 10, 2011, from...

  7. 76 FR 3931 - Fourth Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... Committee 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 Meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems. DATES: The meeting will be held February 8, 2011...

  8. 77 FR 55894 - Fifteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security... meeting of the RTCA Special Committee 224, Airport Security Access Control Systems DATES: The meeting will...

  9. 76 FR 16470 - Sixth Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to... Committee 224: Airport Security Access Control Systems DATES: The meeting will be held April 13, 2011, from...

  10. Optimization of airport security process

    NASA Astrophysics Data System (ADS)

    Wei, Jianan

    2017-05-01

    In order to facilitate passenger travel, on the basis of ensuring public safety, the airport security process and scheduling to optimize. The stochastic Petri net is used to simulate the single channel security process, draw the reachable graph, construct the homogeneous Markov chain to realize the performance analysis of the security process network, and find the bottleneck to limit the passenger throughput. Curve changes in the flow of passengers to open a security channel for the initial state. When the passenger arrives at a rate that exceeds the processing capacity of the security channel, it is queued. The passenger reaches the acceptable threshold of the queuing time as the time to open or close the next channel, simulate the number of dynamic security channel scheduling to reduce the passenger queuing time.

  11. 76 FR 72433 - Revision of Agency Information Collection Activity Under OMB Review: Secure Flight Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-23

    ...] Revision of Agency Information Collection Activity Under OMB Review: Secure Flight Program AGENCY... operators and foreign air carriers submit to Secure Flight for the purposes of watch list matching... screening checkpoint which airport operators will submit to Secure Flight, and a survey of certain general...

  12. 78 FR 43963 - Twenty-Third Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security... meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  13. Prevalence effects in newly trained airport checkpoint screeners: trained observers miss rare targets, too.

    PubMed

    Wolfe, Jeremy M; Brunelli, David N; Rubinstein, Joshua; Horowitz, Todd S

    2013-12-02

    Many socially important search tasks are characterized by low target prevalence, meaning that targets are rarely encountered. For example, transportation security officers (TSOs) at airport checkpoints encounter very few actual threats in carry-on bags. In laboratory-based visual search experiments, low prevalence reduces the probability of detecting targets (Wolfe, Horowitz, & Kenner, 2005). In the lab, this "prevalence effect" is caused by changes in decision and response criteria (Wolfe & Van Wert, 2010) and can be mitigated by presenting a burst of high-prevalence search with feedback (Wolfe et al., 2007). The goal of this study was to see if these effects could be replicated in the field with TSOs. A total of 125 newly trained TSOs participated in one of two experiments as part of their final evaluation following training. They searched for threats in simulated bags across five blocks. The first three blocks were low prevalence (target prevalence ≤ .05) with no feedback; the fourth block was high prevalence (.50) with full feedback; and the final block was, again, low prevalence. We found that newly trained TSOs were better at detecting targets at high compared to low prevalence, replicating the prevalence effect. Furthermore, performance was better (and response criterion was more "liberal") in the low-prevalence block that took place after the high-prevalence block than in the initial three low-prevalence blocks, suggesting that a burst of high-prevalence trials may help alleviate the prevalence effect in the field.

  14. Prevalence effects in newly trained airport checkpoint screeners: Trained observers miss rare targets, too

    PubMed Central

    Wolfe, Jeremy M.; Brunelli, David N.; Rubinstein, Joshua; Horowitz, Todd S.

    2013-01-01

    Many socially important search tasks are characterized by low target prevalence, meaning that targets are rarely encountered. For example, transportation security officers (TSOs) at airport checkpoints encounter very few actual threats in carry-on bags. In laboratory-based visual search experiments, low prevalence reduces the probability of detecting targets (Wolfe, Horowitz, & Kenner, 2005). In the lab, this “prevalence effect” is caused by changes in decision and response criteria (Wolfe & Van Wert, 2010) and can be mitigated by presenting a burst of high-prevalence search with feedback (Wolfe et al., 2007). The goal of this study was to see if these effects could be replicated in the field with TSOs. A total of 125 newly trained TSOs participated in one of two experiments as part of their final evaluation following training. They searched for threats in simulated bags across five blocks. The first three blocks were low prevalence (target prevalence ≤ .05) with no feedback; the fourth block was high prevalence (.50) with full feedback; and the final block was, again, low prevalence. We found that newly trained TSOs were better at detecting targets at high compared to low prevalence, replicating the prevalence effect. Furthermore, performance was better (and response criterion was more “liberal”) in the low-prevalence block that took place after the high-prevalence block than in the initial three low-prevalence blocks, suggesting that a burst of high-prevalence trials may help alleviate the prevalence effect in the field. PMID:24297778

  15. Terrorist Watchlist Checks and Air Passenger Prescreening

    DTIC Science & Technology

    2009-12-30

    U.S. port of entry or at airport security checkpoints prior U.S. air carrier flights. For these purposes, CBP administers the Automated Targeting...Passenger Screening at Airport Security Checkpoints ................................. 14 9/11 Commission Recommendations and CAPPS II...individuals at either international ports of entries upon arrival at a U.S. port of entry or at airport security checkpoints prior U.S. air carrier

  16. [Basic consideration on the security checking of sick travelers at airports].

    PubMed

    Felkai, Péter; Mártai, István

    2012-09-02

    The authorities guarantee the safety of passengers during air travel by strict ground security measures. All of these measures are restrictive and can affect the health status of both healthy and ill travelers. Patients who are in critical condition or confined to a stretcher and have to be repatriated by stretcher on a regular flight, must pass the airport security check as well. But the developers of security system should take into account the medical safety of patients during the procedure. The relevant medical principles are painfully missing not only in Hungary, but unfortunately also at most international airports. On the basis of principles reviewed in the present publication, an unambiguous, professionally reconciled regulation is necessary that would serve as a guideline for airport management and authorities, as well as for the involved medical personnel. Although setting principles into practice requires a different solution at each airport, yet, passenger safety and patient safety have to be harmonized as soon as possible.

  17. Airport Managers' Perspectives on Security and Safety Management Systems in Aviation Operations: A Multiple Case Study

    NASA Astrophysics Data System (ADS)

    Brown, Willie L., Jr.

    Global terrorism continues to persist despite the great efforts of various countries to protect and safely secure their citizens. As airports form the entry and exit ports of a country, they are one of the most vulnerable locations to terror attacks. Managers of international airports constantly face similar challenges in developing and implementing airport security protocols. Consequently, the technological advances of today have brought both positive and negative impacts on security and terrorism of airports, which are mostly managed by the airport managers. The roles of the managers have greatly increased over the years due to technological advances. The developments in technology have had different roles in security, both in countering terrorism and, at the same time, increasing the communication methods of the terrorists. The purpose of this qualitative multiple case study was to investigate the perspectives of airport managers with regard to societal security and social interactions in the socio-technical systems of the National Terrorism Advisory System (NTAS). Through the data gained regarding managers' perception and experiences, the researcher hoped to enable the development of security measures and policies that are appropriate for airports as socio-technical systems. The researcher conducted interviews with airport managers to gather relevant data to fulfill the rationale of the study. Ten to twelve airport managers based in three commercial aviation airports in Maryland, United States participated in the study. The researcher used a qualitative thematic analysis procedure to analyze the data responses of participants in the interview sessions.

  18. 33 CFR 165.1192 - Security Zones; Waters surrounding San Francisco International Airport and Oakland International...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Security Zones; Waters... Security Zones; Waters surrounding San Francisco International Airport and Oakland International Airport, San Francisco Bay, California. (a) Locations. The following areas are security zones: (1) San...

  19. 33 CFR 165.1192 - Security Zones; Waters surrounding San Francisco International Airport and Oakland International...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Security Zones; Waters... Security Zones; Waters surrounding San Francisco International Airport and Oakland International Airport, San Francisco Bay, California. (a) Locations. The following areas are security zones: (1) San...

  20. 33 CFR 165.1192 - Security Zones; Waters surrounding San Francisco International Airport and Oakland International...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Security Zones; Waters... Security Zones; Waters surrounding San Francisco International Airport and Oakland International Airport, San Francisco Bay, California. (a) Locations. The following areas are security zones: (1) San...

  1. 33 CFR 165.1192 - Security Zones; Waters surrounding San Francisco International Airport and Oakland International...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Security Zones; Waters... Security Zones; Waters surrounding San Francisco International Airport and Oakland International Airport, San Francisco Bay, California. (a) Locations. The following areas are security zones: (1) San...

  2. 33 CFR 165.1192 - Security Zones; Waters surrounding San Francisco International Airport and Oakland International...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zones; Waters... Security Zones; Waters surrounding San Francisco International Airport and Oakland International Airport, San Francisco Bay, California. (a) Locations. The following areas are security zones: (1) San...

  3. Examining Passenger Flow Choke Points at Airports Using Discrete Event Simulation

    NASA Technical Reports Server (NTRS)

    Brown, Jeremy R.; Madhavan, Poomima

    2011-01-01

    The movement of passengers through an airport quickly, safely, and efficiently is the main function of the various checkpoints (check-in, security. etc) found in airports. Human error combined with other breakdowns in the complex system of the airport can disrupt passenger flow through the airport leading to lengthy waiting times, missing luggage and missed flights. In this paper we present a model of passenger flow through an airport using discrete event simulation that will provide a closer look into the possible reasons for breakdowns and their implications for passenger flow. The simulation is based on data collected at Norfolk International Airport (ORF). The primary goal of this simulation is to present ways to optimize the work force to keep passenger flow smooth even during peak travel times and for emergency preparedness at ORF in case of adverse events. In this simulation we ran three different scenarios: real world, increased check-in stations, and multiple waiting lines. Increased check-in stations increased waiting time and instantaneous utilization. while the multiple waiting lines decreased both the waiting time and instantaneous utilization. This simulation was able to show how different changes affected the passenger flow through the airport.

  4. 76 FR 59481 - Ninth Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... Control Systems (Update to DO-230B): Agenda October 20, 2011 Welcome/Introductions/Administrative Remarks... 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems. SUMMARY...

  5. 76 FR 50811 - Eighth Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-16

    ... Control Systems (Update to DO-230B): Agenda September 15, 2011 Welcome/Introductions/Administrative... Committee 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems. SUMMARY...

  6. 76 FR 38742 - Seventh Meeting: RTCA Special Committee 224: Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... Control Systems (Update to DO-230B): Agenda July 15, 2011 Welcome/Introductions/Administrative Remarks... Committee 224: Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 224 meeting: Airport Security Access Control Systems (Update to...

  7. Interacting forms of expertise in security governance: the example of CCTV surveillance at Geneva International Airport.

    PubMed

    Klauser, Francisco

    2009-06-01

    The paper investigates the multiple public-private exchanges and cooperation involved in the installation and development of CCTV surveillance at Geneva International Airport. Emphasis is placed on the interacting forms of authority and expertise of five parties: the user(s), owner and supplier of the camera system, as well as the technical managers of the airport and the Swiss regulatory bodies in airport security. While placing the issues of airport surveillance in the particular context of a specific range of projects and transformations relating to the developments of CCTV at Geneva Airport, the paper not only provides important insights into the micro-politics of surveillance at Geneva Airport, but aims to re-institute these as part of a broader 'problematic': the mediating role of expertise and the growing functional fragmentation of authority in contemporary security governance. On this basis, the paper also exemplifies the growing mutual interdependences between security and business interests in the ever growing 'surveillant assemblage' in contemporary security governance.

  8. A model of airport security work flow based on petri net

    NASA Astrophysics Data System (ADS)

    Dong, Xinming

    2017-09-01

    Extremely long lines at airports in the United States have been sharply criticized. In order to find out the bottleneck in the existing security system and put forward reasonable improvement plans and proposal, the Petri net model and the Markov Chain are introduced in this paper. This paper uses data collected by transportation Security Agency (TSA), assuming the data can represent the average level of all airports in the Unites States, to analysis the performance of security check system. By calculating the busy probabilities and the utilization probabilities, the bottleneck is found. Moreover, recommendation is given based on the parameters’ modification in Petri net model.

  9. 77 FR 71474 - Seventeenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the seventeenth meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  10. 78 FR 7850 - Nineteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the nineteenth meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  11. 77 FR 2343 - Eleventh Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-17

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the eleventh meeting of RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting will be held...

  12. 77 FR 25525 - Thirteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-30

    ... Committee 224, Airport Security Access Control Systems. AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the thirteenth meeting of RTCA Special Committee 224, Airport Security Access Control Systems DATES: The meeting will be...

  13. 77 FR 15448 - Twelfth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-15

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the twelfth meeting of RTCA Special Committee 224, Airport Security Access Control Systems DATES: The meeting will be...

  14. Los Alamos Shows Airport Security Technology at Work

    ScienceCinema

    Espy, Michelle; Schultz, Larry; Hunter, James

    2018-05-30

    Los Alamos scientists have advanced a Magnetic Resonance Imaging (MRI) technology that may provide a breakthrough for screening liquids at airport security. They've added low-power X-ray data to the mix, and as a result have unlocked a new detection technology. Funded in part by the Department of Homeland Security's Science and Technology Directorate, the new system is named MagRay. The goal is to quickly and accurately distinguish between liquids that visually appear identical. For example, what appears to be a bottle of white wine could potentially be nitromethane, a liquid that could be used to make an explosive. Both are clear liquids, one would be perfectly safe on a commercial aircraft, the other would be strictly prohibited. How to tell them apart quickly without error at an airport security area is the focus of Michelle Espy, Larry Schultz and their team. In this video, Espy and the MagRay team explain how the new technology works, how they've developed an easy operator interface, and what the next steps might be in transitioning this technology to the private sector.

  15. Los Alamos Shows Airport Security Technology at Work

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Espy, Michelle; Schultz, Larry; Hunter, James

    Los Alamos scientists have advanced a Magnetic Resonance Imaging (MRI) technology that may provide a breakthrough for screening liquids at airport security. They've added low-power X-ray data to the mix, and as a result have unlocked a new detection technology. Funded in part by the Department of Homeland Security's Science and Technology Directorate, the new system is named MagRay. The goal is to quickly and accurately distinguish between liquids that visually appear identical. For example, what appears to be a bottle of white wine could potentially be nitromethane, a liquid that could be used to make an explosive. Both aremore » clear liquids, one would be perfectly safe on a commercial aircraft, the other would be strictly prohibited. How to tell them apart quickly without error at an airport security area is the focus of Michelle Espy, Larry Schultz and their team. In this video, Espy and the MagRay team explain how the new technology works, how they've developed an easy operator interface, and what the next steps might be in transitioning this technology to the private sector.« less

  16. 78 FR 31627 - Twenty-Second Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the twenty-second meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  17. 78 FR 22025 - Twenty First Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S... Access Control Systems. SUMMARY: The FAA is issuing this notice to advise the public of the twenty first meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

  18. On determining specifications and selections of alternative technologies for airport checked-baggage security screening.

    PubMed

    Feng, Qianmei

    2007-10-01

    Federal law mandates that every checked bag at all commercial airports be screened by explosive detection systems (EDS), explosive trace detection systems (ETD), or alternative technologies. These technologies serve as critical components of airport security systems that strive to reduce security risks at both national and global levels. To improve the operational efficiency and airport security, emerging image-based technologies have been developed, such as dual-energy X-ray (DX), backscatter X-ray (BX), and multiview tomography (MVT). These technologies differ widely in purchasing cost, maintenance cost, operating cost, processing rate, and accuracy. Based on a mathematical framework that takes into account all these factors, this article investigates two critical issues for operating screening devices: setting specifications for continuous security responses by different technologies; and selecting technology or combination of technologies for efficient 100% baggage screening. For continuous security responses, specifications or thresholds are used for classifying threat items from nonthreat items. By investigating the setting of specifications on system security responses, this article assesses the risk and cost effectiveness of various technologies for both single-device and two-device systems. The findings provide the best selection of image-based technologies for both single-device and two-device systems. Our study suggests that two-device systems outperform single-device systems in terms of both cost effectiveness and accuracy. The model can be readily extended to evaluate risk and cost effectiveness of multiple-device systems for airport checked-baggage security screening.

  19. Cobalt Chrome Spinal Constructs Trigger Airport Security Screening in 24% of Pediatric Patients.

    PubMed

    Woon, Regina P; Andras, Lindsay M; Barrett, Kody K; Skaggs, David L

    2015-03-01

    Retrospective study. To determine whether pediatric patients undergo additional airport security screening after posterior spinal fusion. Airport security has expanded to include body scanners as well as traditional metal detectors. Families frequently ask whether spinal implants will trigger airport security, but there is limited information on modern implants and screening methods. The researchers conducted a survey of 50 pediatric patients after posterior spinal fusion from 2004 to 2013. Inclusion criteria were posterior instrumentation, pedicle screws for at least 80% of anchors, and at least 1 trip through an American airport after surgery. Charts and radiographs were reviewed for metal type, number of levels fused, number of anchors, and rod diameter. A total of 16% of patients (8 of 50) were detected by body scan or metal detector and all had cobalt chrome (CoCr) rods. No patients with stainless-steel (SS) rods were detected. The CoCr rods triggered additional screening in 24% of children (8 of 33), compared with none of 17 with SS rods (p = .03). For patients with CoCr rods, the detection rate was 18% (5 of 28) by metal detector and 17% (3 of 18) by body scanner. For patients with CoCr rods, there was no significant difference between detection rates and levels fused (p = .30), number of anchors (p = .15), or rod diameter (p = .17). In this series, CoCr constructs were more likely to incur additional airport security compared with more traditional SS constructs. Copyright © 2015 Scoliosis Research Society. Published by Elsevier Inc. All rights reserved.

  20. An RFID-based luggage and passenger tracking system for airport security control applications

    NASA Astrophysics Data System (ADS)

    Vastianos, George E.; Kyriazanos, Dimitris M.; Kountouriotis, Vassilios I.; Thomopoulos, Stelios C. A.

    2014-06-01

    Market analysis studies of recent years have shown a steady and significant increase in the usage of RFID technology. Key factors for this growth were the decreased costs of passive RFIDs and their improved performance compared to the other identification technologies. Besides the benefits of RFID technologies into the supply chains, warehousing, traditional inventory and asset management applications, RFID has proven itself worth exploiting on experimental, as well as on commercial level in other sectors, such as healthcare, transport and security. In security sector, airport security is one of the biggest challenges. Airports are extremely busy public places and thus prime targets for terrorism, with aircraft, passengers, crew and airport infrastructure all subject to terrorist attacks. Inside this labyrinth of security challenges, the long range detection capability of the UHF passive RFID technology can be turned into a very important tracking tool that may outperform all the limitations of the barcode tracking inside the current airport security control chain. The Integrated Systems Lab of NCSR Demokritos has developed an RFID based Luggage and Passenger tracking system within the TASS (FP7-SEC-2010-241905) EU research project. This paper describes application scenarios of the system categorized according to the structured nature of the environment, the system architecture and presents evaluation results extracted from measurements with a group of different massive production GEN2 UHF RFID tags that are widely available in the world market.

  1. Specific-Token Effects in Screening Tasks: Possible Implications for Aviation Security

    ERIC Educational Resources Information Center

    Smith, J. David; Redford, Joshua S.; Washburn, David A.; Taglialatela, Lauren A.

    2005-01-01

    Screeners at airport security checkpoints perform an important categorization task in which they search for threat items in complex x-ray images. But little is known about how the processes of categorization stand up to visual complexity. The authors filled this research gap with screening tasks in which participants searched for members of target…

  2. Agency Problems and Airport Security: Quantitative and Qualitative Evidence on the Impact of Security Training.

    PubMed

    de Gramatica, Martina; Massacci, Fabio; Shim, Woohyun; Turhan, Uğur; Williams, Julian

    2017-02-01

    We analyze the issue of agency costs in aviation security by combining results from a quantitative economic model with a qualitative study based on semi-structured interviews. Our model extends previous principal-agent models by combining the traditional fixed and varying monetary responses to physical and cognitive effort with nonmonetary welfare and potentially transferable value of employees' own human capital. To provide empirical evidence for the tradeoffs identified in the quantitative model, we have undertaken an extensive interview process with regulators, airport managers, security personnel, and those tasked with training security personnel from an airport operating in a relatively high-risk state, Turkey. Our results indicate that the effectiveness of additional training depends on the mix of "transferable skills" and "emotional" buy-in of the security agents. Principals need to identify on which side of a critical tipping point their agents are to ensure that additional training, with attached expectations of the burden of work, aligns the incentives of employees with the principals' own objectives. © 2016 Society for Risk Analysis.

  3. Authoritarianism among border police officers, career soldiers, and airport security guards at the Israeli border.

    PubMed

    Rubinstein, Gidi

    2006-12-01

    Several personality theories focusing on specific personality variables involved in career choice and job satisfaction are based on the assumption that individuals choose certain career choices because they believe that they may be able to meet their emotional needs (J. L. Holland, 1977). The author of this study investigated the personality traits of border police officers, career soldiers, and airport security guards in Israel. The participants were 160 men--40 border policemen, 40 career soldiers, 40 airport security guards, and 40 control participants--who filled out a demographic questionnaire and a Hebrew version of the right-wing authoritarianism (RWA) shortened scale (B. Altemeyer, personal communication, February 2000). The present hypothesis predicted that the RWA scores of border police officers would be the highest, followed by those of career soldiers, airport security guards, and control participants, in that order. Statistically significant differences in RWA scores occurred between these groups in the predicted order, with the exception of the career soldiers' RWA scores, which did not significantly differ from those of the airport security guards.

  4. FlySec: a risk-based airport security management system based on security as a service concept

    NASA Astrophysics Data System (ADS)

    Kyriazanos, Dimitris M.; Segou, Olga E.; Zalonis, Andreas; Thomopoulos, Stelios C. A.

    2016-05-01

    Complementing the ACI/IATA efforts, the FLYSEC European H2020 Research and Innovation project (http://www.fly-sec.eu/) aims to develop and demonstrate an innovative, integrated and end-to-end airport security process for passengers, enabling a guided and streamlined procedure from the landside to airside and into the boarding gates, and offering for an operationally validated innovative concept for end-to-end aviation security. FLYSEC ambition turns through a well-structured work plan into: (i) innovative processes facilitating risk-based screening; (ii) deployment and integration of new technologies and repurposing existing solutions towards a risk-based Security paradigm shift; (iii) improvement of passenger facilitation and customer service, bringing security as a real service in the airport of tomorrow;(iv) achievement of measurable throughput improvement and a whole new level of Quality of Service; and (v) validation of the results through advanced "in-vitro" simulation and "in-vivo" pilots. On the technical side, FLYSEC achieves its ambitious goals by integrating new technologies on video surveillance, intelligent remote image processing and biometrics combined with big data analysis, open-source intelligence and crowdsourcing. Repurposing existing technologies is also in the FLYSEC objectives, such as mobile application technologies for improved passenger experience and positive boarding applications (i.e. services to facilitate boarding and landside/airside way finding) as well as RFID for carry-on luggage tracking and quick unattended luggage handling. In this paper, the authors will describe the risk based airport security management system which powers FLYSEC intelligence and serves as the backend on top of which FLYSEC's front end technologies reside for security services management, behaviour and risk analysis.

  5. Predicting Airport Screening Officers' Visual Search Competency With a Rapid Assessment.

    PubMed

    Mitroff, Stephen R; Ericson, Justin M; Sharpe, Benjamin

    2018-03-01

    Objective The study's objective was to assess a new personnel selection and assessment tool for aviation security screeners. A mobile app was modified to create a tool, and the question was whether it could predict professional screeners' on-job performance. Background A variety of professions (airport security, radiology, the military, etc.) rely on visual search performance-being able to detect targets. Given the importance of such professions, it is necessary to maximize performance, and one means to do so is to select individuals who excel at visual search. A critical question is whether it is possible to predict search competency within a professional search environment. Method Professional searchers from the USA Transportation Security Administration (TSA) completed a rapid assessment on a tablet-based X-ray simulator (XRAY Screener, derived from the mobile technology app Airport Scanner; Kedlin Company). The assessment contained 72 trials that were simulated X-ray images of bags. Participants searched for prohibited items and tapped on them with their finger. Results Performance on the assessment significantly related to on-job performance measures for the TSA officers such that those who were better XRAY Screener performers were both more accurate and faster at the actual airport checkpoint. Conclusion XRAY Screener successfully predicted on-job performance for professional aviation security officers. While questions remain about the underlying cognitive mechanisms, this quick assessment was found to significantly predict on-job success for a task that relies on visual search performance. Application It may be possible to quickly assess an individual's visual search competency, which could help organizations select new hires and assess their current workforce.

  6. Optimisation of Critical Infrastructure Protection: The SiVe Project on Airport Security

    NASA Astrophysics Data System (ADS)

    Breiing, Marcus; Cole, Mara; D'Avanzo, John; Geiger, Gebhard; Goldner, Sascha; Kuhlmann, Andreas; Lorenz, Claudia; Papproth, Alf; Petzel, Erhard; Schwetje, Oliver

    This paper outlines the scientific goals, ongoing work and first results of the SiVe research project on critical infrastructure security. The methodology is generic while pilot studies are chosen from airport security. The outline proceeds in three major steps, (1) building a threat scenario, (2) development of simulation models as scenario refinements, and (3) assessment of alternatives. Advanced techniques of systems analysis and simulation are employed to model relevant airport structures and processes as well as offences. Computer experiments are carried out to compare and optimise alternative solutions. The optimality analyses draw on approaches to quantitative risk assessment recently developed in the operational sciences. To exploit the advantages of the various techniques, an integrated simulation workbench is build up in the project.

  7. [Airport security check of medical substances used during patient repatriation].

    PubMed

    Felkai, Péter

    2012-09-16

    During airport security check of passenger luggage, hazardous items and substances are prohibited to be taken into the restricted safety zone of the airport and the aircraft. Among equipment of the medical staff escorting the patient, there are several devices and materials which are considered hazardous for security reasons. However, medical equipment and substances are indispensable for treating patients during the flight. The aim of the author was to present his experience obtained with the use of an instrument developed for testing liquids, aerosols and gels for security reasons. An instrument based on Raman spectroscopy was used for the identification of medical substances. The results confirmed that the instrument was able to recognize the tested medical substances. The non-destructive testing maintained sample integrity and asepsis. The data indicate that the instrument has a promising utility for the identification of medical substances. It seems important that during repatriation medical substances should be selected not only on the ground of their medical necessity, but their packaging should be also taken into consideration. It is necessary to perform more tests on different medical substances used in emergency care in order to make the database of medical substances stored in the library of instrument more complete.

  8. Review of the Literature Related to Screening Airline Passenger Baggage.

    DTIC Science & Technology

    1994-10-01

    11 billion passengers and their carry-on items have passed through airport security checkpoints. According to the Federal Aviation Administration...Aviation Security establishes security requirements, inspects airline and airport security operations, and issues civil penalties for noncompliance with...operations areas and provide law enforcement support for the screening system and overall airport security requirements (FAA, 1991). The FAA’s role in aviation

  9. Finite-Time Performance of Local Search Algorithms: Theory and Application

    DTIC Science & Technology

    2010-06-10

    security devices deployed at airport security checkpoints are used to detect prohibited items (e.g., guns, knives, explosives). Each security device...security devices are deployed, the practical issue of determining how to optimally use them can be difficult. For an airport security system design...checked baggage), explosive detection systems (designed to detect explosives in checked baggage), and detailed hand search by an airport security official

  10. 33 CFR 165.113 - Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA 165.113 Section 165.113 Navigation and Navigable Waters..., MA (a) Location. The permanent security zone consists of four sectors that may be activated in part...

  11. 33 CFR 165.113 - Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA 165.113 Section 165.113 Navigation and Navigable Waters..., MA (a) Location. The permanent security zone consists of four sectors that may be activated in part...

  12. 33 CFR 165.113 - Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA. 165.113 Section 165.113 Navigation and Navigable Waters..., MA. (a) Location. The permanent security zone consists of four sectors that may be activated in part...

  13. 33 CFR 165.113 - Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA. 165.113 Section 165.113 Navigation and Navigable Waters..., MA. (a) Location. The permanent security zone consists of four sectors that may be activated in part...

  14. 33 CFR 165.113 - Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA 165.113 Section 165.113 Navigation and Navigable Waters..., MA (a) Location. The permanent security zone consists of four sectors that may be activated in part...

  15. Just How Much Does That Cost, Anyway? An Analysis of the Financial Costs and Benefits of the No-Fly List

    DTIC Science & Technology

    2009-01-01

    easier and more streamlined airport security checkpoint experience. Having outlined the key aspects of the no-fly list, the article will now turn...attempts to fly, he/she is stopped at the airport by local law enforcement and airport security . Having identified how many false positives there are in a...activities: the cost of the passenger being detained at the airport and missing his/her flight; the cost of airport security /personnel detaining the

  16. Airport technology international 1993

    NASA Astrophysics Data System (ADS)

    Papagiorcopulo, George

    The present survey of developments in airport technologies and their management discusses airport extensions and upgradings, airport developments in China, polluter penalization, airport effects on environments, European ground-handling methods, ATC in Europe, EC duty-free sales at airports, and the privatization of airport security. Also discussed are airport advertising, new alternatives in air-cargo handling, ATC training, taxi-guidance systems, and the reduction of fuel consumption and emissions on the ground. (No individual items are abstracted in this volume)

  17. 49 CFR 1542.201 - Security of the secured area.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.201 Security of the secured area. (a) Each airport operator required to have a security... posted by each airport operator in accordance with its security program not later than November 14, 2003. ...

  18. 49 CFR 1542.201 - Security of the secured area.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.201 Security of the secured area. (a) Each airport operator required to have a security... posted by each airport operator in accordance with its security program not later than November 14, 2003. ...

  19. 49 CFR 1542.201 - Security of the secured area.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.201 Security of the secured area. (a) Each airport operator required to have a security... posted by each airport operator in accordance with its security program not later than November 14, 2003. ...

  20. 49 CFR 1542.201 - Security of the secured area.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.201 Security of the secured area. (a) Each airport operator required to have a security... posted by each airport operator in accordance with its security program not later than November 14, 2003. ...

  1. 49 CFR 1542.201 - Security of the secured area.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.201 Security of the secured area. (a) Each airport operator required to have a security... posted by each airport operator in accordance with its security program not later than November 14, 2003. ...

  2. Effect of total shoulder replacements on airport security screening in the post-9/11 era.

    PubMed

    Dines, Joshua S; Elkousy, Hussein; Edwards, T Bradley; Gartsman, Gary M; Dines, David M

    2007-01-01

    There are few reports in the literature on the effect of orthopaedic implants on airport security devices and none on shoulder arthroplasty implants after September 11, 2001. Since 9/11, airport security screening devices have become more sensitive in response to the increasing threat of terrorism. Often, patients with joint implants activate the metal detectors and are subsequently subjected to more intensive screening. We assess the effects of shoulder joint implants on different airport security devices and what effect the results had on passenger travel. In this study, 154 patients who had previously undergone shoulder replacement responded to a questionnaire regarding their travel experiences after 9/11. Of these, 85 had flown during the time period studied (47 men and 38 women; mean age, 67.8 years); 79 had traveled domestically (mean, 7 flights), and 22 had taken international flights (mean, 6.1 flights). The questionnaire addressed each patient's height/weight, the number of flight segments flown (domestic and international), the number of times that a patient activated the doorway alarm/wand alarm, and the effect of a card stating that the patient had joint replacement (when applicable). On average, patients with shoulder replacement traveling domestically activated the security gate 52% of the time. The average for international travel was 42%. Of the patients who flew both domestically and internationally, there was a high correlation of activation (R = 0.54). Twenty-six patients had multiple joint implants (mean, 2.8). Multiple joint implants caused increased alarm activation (P < .001). All patients reported that their travel was delayed during the instances of security activation. There was no statistically significant effect of body mass index, height, weight, age, or sex on security device activation. Of the patients, 71% were told by their doctor that the shoulder replacement may activate security devices. Of these, 46 were given a card by their

  3. Evaluation of scattered radiation emitted from X-ray security scanners on occupational dose to airport personnel

    NASA Astrophysics Data System (ADS)

    Dalah, Entesar; Fakhry, Angham; Mukhtar, Asma; Al Salti, Farah; Bader, May; Khouri, Sara; Al-Zahmi, Reem

    2017-06-01

    Based on security issues and regulations airports are provided with luggage cargo scanners. These scanners utilize ionizing radiation that in principle present health risks toward humans. The study aims to investigate the amount of backscatter produced by passenger luggage and cargo toward airport personnel who are located at different distances from the scanners. To approach our investigation a Thermo Electron Radeye-G probe was used to quantify the backscattered radiation measured in terms of dose-rate emitted from airport scanners, Measurements were taken at the entrance and exit positions of the X-ray tunnel at three different distances (0, 50, and 100 cm) for two different scanners; both scanners include shielding curtains that reduce scattered radiation. Correlation was demonstrated using the Pearson coefficient test. Measurements confirmed an inverse relationship between dose rate and distance. An estimated occupational accumulative dose of 0.88 mSv/y, and 2.04 mSv/y were obtained for personnel working in inspection of carry-on, and cargo, respectively. Findings confirm that the projected dose of security and engineering staff are being well within dose limits.

  4. 77 FR 58208 - Airport Privatization Pilot Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ... Department of Transportation (DOT), the Federal Aviation Administration and the Transportation Security... International Airport final application; the Transportation Security Administration will also participate... employees, airlines, aviation businesses and airport tenants, elected officials and community residents...

  5. AVIATION SECURITY: Transportation Security Administration Faces Immediate and Long-Term Challenges

    DTIC Science & Technology

    2002-07-25

    circumvent airport security , and provide whistleblower protection for air carrier and airport security workers. (See app. III for a summary of pending...GAO-01-1171T. Washington, D.C.: September 25, 2001. Aviation Security: Weaknesses in Airport Security and Options for Assigning Screening...125. Washington, D.C.: March 16, 2000. Aviation Security: FAA’s Actions to Study Responsibilities and Funding for Airport Security and to Certify

  6. Emotional Exhaustion and Job Satisfaction in Airport Security Officers - Work-Family Conflict as Mediator in the Job Demands-Resources Model.

    PubMed

    Baeriswyl, Sophie; Krause, Andreas; Schwaninger, Adrian

    2016-01-01

    The growing threat of terrorism has increased the importance of aviation security and the work of airport security officers (screeners). Nonetheless, airport security research has yet to focus on emotional exhaustion and job satisfaction as major determinants of screeners' job performance. The present study bridges this research gap by applying the job demands-resources (JD-R) model and using work-family conflict (WFC) as an intervening variable to study relationships between work characteristics (workload and supervisor support), emotional exhaustion, and job satisfaction in 1,127 screeners at a European airport. Results of structural equation modeling revealed that (a) supervisor support as a major job resource predicted job satisfaction among screeners; (b) workload as a major job demand predicted their emotional exhaustion; and (c) WFC proved to be a promising extension to the JD-R model that partially mediated the impact of supervisor support and workload on job satisfaction and emotional exhaustion. Theoretical and practical implications are discussed.

  7. Checkpointing filesystem

    DOEpatents

    Gara, Alan G.; Giampapa, Mark E.; Steinmacher-Burow, Burkhard D.

    2005-05-17

    The present in invention is directed to a checkpointing filesystem of a distributed-memory parallel supercomputer comprising a node that accesses user data on the filesystem, the filesystem comprising an interface that is associated with a disk for storing the user data. The checkpointing filesystem provides for taking and checkpoint of the filesystem and rolling back to a previously taken checkpoint, as well as for writing user data to and deleting user data from the checkpointing filesystem. The checkpointing filesystem provides a recently written file allocation table (WFAT) for maintaining information regarding the user data written since a previously taken checkpoint and a recently deleted file allocation table (DFAT) for maintaining information regarding user data deleted from since the previously taken checkpoint, both of which are utilized by the checkpointing filesystem to take a checkpoint of the filesystem and rollback the filesystem to a previously taken checkpoint, as well as to write and delete user data from the checkpointing filesystem.

  8. 7 CFR 318.13-10 - Inspection of baggage, other personal effects, and cargo.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the airport security checkpoint or the aircraft boarding gate, at the time they pass through the... in the public areas of the airport. When an inspector has inspected and passed such baggage or..., or aircraft provides space and facilities on the means of conveyance, pier, or airport that are...

  9. 7 CFR 318.13-10 - Inspection of baggage, other personal effects, and cargo.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the airport security checkpoint or the aircraft boarding gate, at the time they pass through the... in the public areas of the airport. When an inspector has inspected and passed such baggage or..., or aircraft provides space and facilities on the means of conveyance, pier, or airport that are...

  10. 7 CFR 318.13-10 - Inspection of baggage, other personal effects, and cargo.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the airport security checkpoint or the aircraft boarding gate, at the time they pass through the... in the public areas of the airport. When an inspector has inspected and passed such baggage or..., or aircraft provides space and facilities on the means of conveyance, pier, or airport that are...

  11. 7 CFR 318.13-10 - Inspection of baggage, other personal effects, and cargo.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the airport security checkpoint or the aircraft boarding gate, at the time they pass through the... in the public areas of the airport. When an inspector has inspected and passed such baggage or..., or aircraft provides space and facilities on the means of conveyance, pier, or airport that are...

  12. 17 CFR 256.310 - Aircraft and airport equipment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Aircraft and airport equipment. 256.310 Section 256.310 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... UTILITY HOLDING COMPANY ACT OF 1935 Service Company Property Accounts § 256.310 Aircraft and airport...

  13. 17 CFR 256.310 - Aircraft and airport equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Aircraft and airport equipment. 256.310 Section 256.310 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... UTILITY HOLDING COMPANY ACT OF 1935 Service Company Property Accounts § 256.310 Aircraft and airport...

  14. Structuring Homeland Security

    DTIC Science & Technology

    2002-04-09

    20 AIRPORT SECURITY .............................................................................................. 20...using an existing command and control structure. Since September 11, 2001 airport security has been of heightened importance to the American public...In order to use Reserves to provide airport security the airports themselves should be made federal property. This would allow greater flexibility for

  15. A review of automated image understanding within 3D baggage computed tomography security screening.

    PubMed

    Mouton, Andre; Breckon, Toby P

    2015-01-01

    Baggage inspection is the principal safeguard against the transportation of prohibited and potentially dangerous materials at airport security checkpoints. Although traditionally performed by 2D X-ray based scanning, increasingly stringent security regulations have led to a growing demand for more advanced imaging technologies. The role of X-ray Computed Tomography is thus rapidly expanding beyond the traditional materials-based detection of explosives. The development of computer vision and image processing techniques for the automated understanding of 3D baggage-CT imagery is however, complicated by poor image resolutions, image clutter and high levels of noise and artefacts. We discuss the recent and most pertinent advancements and identify topics for future research within the challenging domain of automated image understanding for baggage security screening CT.

  16. Emotional Exhaustion and Job Satisfaction in Airport Security Officers – Work–Family Conflict as Mediator in the Job Demands–Resources Model

    PubMed Central

    Baeriswyl, Sophie; Krause, Andreas; Schwaninger, Adrian

    2016-01-01

    The growing threat of terrorism has increased the importance of aviation security and the work of airport security officers (screeners). Nonetheless, airport security research has yet to focus on emotional exhaustion and job satisfaction as major determinants of screeners’ job performance. The present study bridges this research gap by applying the job demands–resources (JD–R) model and using work–family conflict (WFC) as an intervening variable to study relationships between work characteristics (workload and supervisor support), emotional exhaustion, and job satisfaction in 1,127 screeners at a European airport. Results of structural equation modeling revealed that (a) supervisor support as a major job resource predicted job satisfaction among screeners; (b) workload as a major job demand predicted their emotional exhaustion; and (c) WFC proved to be a promising extension to the JD–R model that partially mediated the impact of supervisor support and workload on job satisfaction and emotional exhaustion. Theoretical and practical implications are discussed. PMID:27242581

  17. Airport detectors and orthopaedic implants.

    PubMed

    van der Wal, Bart C H; Grimm, Bernd; Heyligers, Ide C

    2005-08-01

    As a result of the rising threats of terrorism, airport security has become a major issue. Patients with orthopaedic implants are concerned that they may activate alarms at airport security gates. A literature overview showed that the activation rate of the alarm by hand-held detectors is higher than for arch detectors (100% versus 56%). Arch detection rate has significantly increased from 0% before 1995 up to 83.3% after 1994. Reported factors which influence detection rates are implant mass, implant combinations, implant volume, transfer speed, side of implant, detector model, sensitivity settings, material and tissue masking. Detection rate has been improved by more sensitive devices and improved filter software. Doctors should be able to objectively inform patients. A form is presented which will easily inform the airport security staff.

  18. Metallic orthopaedic implants and airport metal detectors.

    PubMed

    Kamineni, S; Legge, S; Ware, H

    2002-01-01

    Airport security can detect in vivo metallic implants. We hypothesized that a soft tissue shield and fast transit through archway detectors would decrease implant detectability, whereas greater implant mass would increase detectability. Twelve patients with 8 orthopaedic implants in vivo and 60 trauma and arthroplasty implants in vitro were subjected to standard airport security measures at Stanstead Airport (British Airports Authority), including arch and standard and nonstandard hand-held detectors. Archway detectors failed to detect some implants; hand-held detectors detected almost all implants except an ankle arthroplasty. Positive archway detection was related to implant transit speed through the detection field. The implant mass consistently affected detection in stainless steel and titanium implants, and a 1-inch wax shield had no effect. Patients with metallic implants should prepare routinely with documentation of their implant before traveling through security ports.

  19. Reprint of 'Evaluation of Scattered Radiation Emitted From X-ray Security Scanners on Occupational Dose to Airport Personnel'

    NASA Astrophysics Data System (ADS)

    Dalah, Entesar; Fakhry, Angham; Mukhtar, Asma; Al Salti, Farah; Bader, May; Khouri, Sara; Al-Zahmi, Reem

    2017-11-01

    Based on security issues and regulations airports are provided with luggage cargo scanners. These scanners utilize ionizing radiation that in principle present health risks toward humans. The study aims to investigate the amount of backscatter produced by passenger luggage and cargo toward airport personnel who are located at different distances from the scanners. To approach our investigation a Thermo Electron Radeye-G probe was used to quantify the backscattered radiation measured in terms of dose-rate emitted from airport scanners, Measurements were taken at the entrance and exit positions of the X-ray tunnel at three different distances (0, 50, and 100 cm) for two different scanners; both scanners include shielding curtains that reduce scattered radiation. Correlation was demonstrated using the Pearson coefficient test. Measurements confirmed an inverse relationship between dose rate and distance. An estimated occupational accumulative dose of 0.88 mSv/y, and 2.04 mSv/y were obtained for personnel working in inspection of carry-on, and cargo, respectively. Findings confirm that the projected dose of security and engineering staff are being well within dose limits.

  20. An Analysis of Federal Airport and Air Carrier Employee Access Control, Screening. and Training Regulations

    DTIC Science & Technology

    1998-03-01

    traveling public, air carriers, and persons employed by or conducting business at public airports. 14. SUBJECT TERMS Airport Security , Federal...26 4. Sterile Area 28 5. Exclusive Area 28 E. SECURITY ALERT LEVELS 29 F. AIRPORT SECURITY TOOLS 30 1. Electronic Detection System 31 a... Security Coordinator ASP Airport Security Program BIS Biometrie Identification System CCTV Closed Circuit Television CJIS Criminal Justice Information

  1. Sensitive Security Information (SSI) and Transportation Security: Background and Controversies

    DTIC Science & Technology

    2004-02-05

    with airport security procedures, employee accountability, passenger screening, and airport secrecy agreements. In January 2003, the Dallas/Fort... Airport Security Flaws Bring Criticism,” Los Angeles Times, July 2, 2002, p. A8. 16 Charles Piller and Ricardo Alonso-Zaldivar, “A Suspect Computer...Secrecy in Airport Security Contract Criticized,” Des Moines Register, Sept. 27, 2003, p. 1A; James Andrews, “Here in Tristate, Security’s Tighter

  2. 78 FR 51810 - Twenty-Fourth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ...., 1150 18th Street NW., Suite 910, Washington, DC 20036. FOR FURTHER INFORMATION CONTACT: The RTCA... (202) 833-9434, or Web site at http://www.rtca.org . SUPPLEMENTARY INFORMATION: Pursuant to section 10... Security System Standard for Airport Access Control, RTCA Paper No. 168-13/SC224-048 TOR Review--Status of...

  3. A Surveillance Society and the Conflict State: Leveraging Ubiquitous Surveillance and Biometrics Technology to Improve Homeland Security

    DTIC Science & Technology

    2002-09-01

    customs checkpoints. In 2000, customs officials had already deployed these body scanners at JFK Airport in New York, Miami International, Chicago’s... JFK Airport in New York City and Dulles Airport in Washington, D.C. are also considering JetStream trials (Guevin, 9 Apr 2002). Although six of the

  4. 49 CFR 1560.111 - Covered airport operators.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Covered airport operators. 1560.111 Section 1560... Transmission of Secure Flight Passenger Data for Watch List Matching § 1560.111 Covered airport operators. (a) Applicability. This section applies to a covered airport operator that has a program approved by TSA through...

  5. 49 CFR 1560.111 - Covered airport operators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Covered airport operators. 1560.111 Section 1560... Transmission of Secure Flight Passenger Data for Watch List Matching § 1560.111 Covered airport operators. (a) Applicability. This section applies to a covered airport operator that has a program approved by TSA through...

  6. 49 CFR 1560.111 - Covered airport operators.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Covered airport operators. 1560.111 Section 1560... Transmission of Secure Flight Passenger Data for Watch List Matching § 1560.111 Covered airport operators. (a) Applicability. This section applies to a covered airport operator that has a program approved by TSA through...

  7. 49 CFR 1560.111 - Covered airport operators.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Covered airport operators. 1560.111 Section 1560... Transmission of Secure Flight Passenger Data for Watch List Matching § 1560.111 Covered airport operators. (a) Applicability. This section applies to a covered airport operator that has a program approved by TSA through...

  8. 49 CFR 1560.111 - Covered airport operators.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Covered airport operators. 1560.111 Section 1560... Transmission of Secure Flight Passenger Data for Watch List Matching § 1560.111 Covered airport operators. (a) Applicability. This section applies to a covered airport operator that has a program approved by TSA through...

  9. 49 CFR 1544.231 - Airport-approved and exclusive area personnel identification systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRCRAFT OPERATOR SECURITY: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.231 Airport-approved... 49 Transportation 9 2013-10-01 2013-10-01 false Airport-approved and exclusive area personnel...

  10. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1980-05-22

    SECURITY. - CONTINUED TRAINING OF LAW ENFORCEMENT OFFICERS SUPPORTING AIRPORT SECURITY ACTIVITIES. - SECURITY PROGRAMS IMPLEMENTED BY AIR FREIGHT...cooperation by all concerned. (See Exhibit 14) Airport Security - Ongoing activities which contributed significantly to airport security included full...implementation of the revised Federal Aviation Regulations (FAR) Part 107 governing airport security , training of law enforcement officers supporting

  11. 49 CFR 1542.107 - Changed conditions affecting security.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Airport... notification in writing. If approved by TSA, this written notification becomes a part of the airport security... section in the form of a proposed amendment to the airport operator's security program, as required under...

  12. 49 CFR 1542.107 - Changed conditions affecting security.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Airport... notification in writing. If approved by TSA, this written notification becomes a part of the airport security... section in the form of a proposed amendment to the airport operator's security program, as required under...

  13. 49 CFR 1542.107 - Changed conditions affecting security.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Airport... notification in writing. If approved by TSA, this written notification becomes a part of the airport security... section in the form of a proposed amendment to the airport operator's security program, as required under...

  14. 49 CFR 1542.107 - Changed conditions affecting security.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Airport... notification in writing. If approved by TSA, this written notification becomes a part of the airport security... section in the form of a proposed amendment to the airport operator's security program, as required under...

  15. 49 CFR 1542.107 - Changed conditions affecting security.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Airport... notification in writing. If approved by TSA, this written notification becomes a part of the airport security... section in the form of a proposed amendment to the airport operator's security program, as required under...

  16. 19 CFR 122.15 - User fee airports.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false User fee airports. 122.15 Section 122.15 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY AIR COMMERCE REGULATIONS Classes of Airports § 122.15 User fee airports. (a) Permission to land. The procedures for obtaining permission to land at...

  17. 19 CFR 122.15 - User fee airports.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false User fee airports. 122.15 Section 122.15 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY AIR COMMERCE REGULATIONS Classes of Airports § 122.15 User fee airports. (a) Permission to land. The procedures for obtaining permission to land at...

  18. 49 CFR 1554.101 - Security Measures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... certificated repair stations located— (1) On airport. On an air operations area or security identification display area of an airport covered by an airport security program under 49 CFR part 1542 in the United States, or on the security restricted area of any commensurate airport outside the United States...

  19. Aviation Security: Vulnerabilities in, and Alternatives for, Preboard Screening Security Operations

    DTIC Science & Technology

    2001-09-25

    establishing the certification program. This regulation is particularly significant because it is to include requirements mandated by the Airport Security Improvement...Assessment of Airport Security Screener Performance and Retention, Sept. 15, 2000. Page 8 GAO-01-1171T Criteria for Assessing Shifting responsibility for...airline and airport security officials to assess each option for reassigning screening responsibility against the key criteria- Specifically, we asked

  20. Aviation Security: A Case for Risk-Based Passenger Screening

    DTIC Science & Technology

    2011-12-01

    5 3. Threat Uncertainty ..............................................................................7 4. Increased Risk and Cost ...Airport Checkpoints .....................................131 ix 2. Technology Integration and Implementation Costs .....................131 3...Background Investigations and Sustaining Program Costs ........133 D. AREAS FOR FUTURE RESEARCH

  1. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1981-11-09

    which have been prevented or deterred by airline and airport security procedures cannot be determined with certainty. The Federal Aviation Administration...finalized and issued. The new FAR Part 108, Air Carrier Security and complementary changes to FAR Part 107, Airport Security , and FAR Part 129, Operations...initiated audit of the claims and, if verified, action will be taken to seek funding for payment. Airport Security . Airport security measures continue to be

  2. Airport Remote Tower Sensor Systems

    NASA Technical Reports Server (NTRS)

    Maluf, David A.; Gawdiak, Yuri; Leidichj, Christopher; Papasin, Richard; Tran, Peter B.; Bass, Kevin

    2006-01-01

    Networks of video cameras, meteorological sensors, and ancillary electronic equipment are under development in collaboration among NASA Ames Research Center, the Federal Aviation Administration (FAA), and the National Oceanic Atmospheric Administration (NOAA). These networks are to be established at and near airports to provide real-time information on local weather conditions that affect aircraft approaches and landings. The prototype network is an airport-approach-zone camera system (AAZCS), which has been deployed at San Francisco International Airport (SFO) and San Carlos Airport (SQL). The AAZCS includes remotely controlled color video cameras located on top of SFO and SQL air-traffic control towers. The cameras are controlled by the NOAA Center Weather Service Unit located at the Oakland Air Route Traffic Control Center and are accessible via a secure Web site. The AAZCS cameras can be zoomed and can be panned and tilted to cover a field of view 220 wide. The NOAA observer can see the sky condition as it is changing, thereby making possible a real-time evaluation of the conditions along the approach zones of SFO and SQL. The next-generation network, denoted a remote tower sensor system (RTSS), will soon be deployed at the Half Moon Bay Airport and a version of it will eventually be deployed at Los Angeles International Airport. In addition to remote control of video cameras via secure Web links, the RTSS offers realtime weather observations, remote sensing, portability, and a capability for deployment at remote and uninhabited sites. The RTSS can be used at airports that lack control towers, as well as at major airport hubs, to provide synthetic augmentation of vision for both local and remote operations under what would otherwise be conditions of low or even zero visibility.

  3. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1979-12-05

    The airline and airport security measures currently in effect continue to provide increased safety for airline passengers and crews as well as...107 governing airport security . other ongoing programs which contributed significantly to airport security included the training of law enforce- ment...officers supporting airport security programs and the explosives detection K(9 team program. Highlights of these actions and programs are summarized

  4. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1980-10-14

    CEASE FUNDING OF TRAINING"OF LAW ENFORCEMENT OFFICERS SUPPORTING AIRPORT SECURITY ACTIVITIES. F. FEDERAL AIR MARSHALS PROVIDE LAW ENFORCEMENT SUPPORT...enforcement officer authority through special deputations by the U.S. Marshals Service on an annual basis. Airport Security - Continuing activities...which contributed signifi- cantly to airport security include the training of local law enforcement officers supporting airport security programs, the

  5. 76 FR 49503 - Intent To Request Renewal From OMB of One Current Public Collection of Information: Airport Security

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ...The Transportation Security Administration (TSA) invites public comment on one currently approved Information Collection Request (ICR), Office of Management and Budget (OMB) control number 1652-0002, abstracted below that we will submit to OMB for renewal in compliance with the Paperwork Reduction Act (PRA). The ICR describes the nature of the information collection and its expected burden. These programs require airport operators to maintain and update records to ensure compliance with security provisions outlined in 49 CFR part 1542.

  6. Conservation science in a terrorist age: the impact of airport security screening on the viability and DNA integrity of frozen felid spermatozoa.

    PubMed

    Gloor, Kayleen T; Winget, Doug; Swanson, William F

    2006-09-01

    In response to growing terrorism concerns, the Transportation Security Administration now requires that all checked baggage at U.S. airports be scanned through a cabinet x-ray system, which may increase risk of radiation damage to transported biologic samples and other sensitive genetic material. The objective of this study was to investigate the effect of these new airport security regulations on the viability and DNA integrity of frozen felid spermatozoa. Semen was collected from two domestic cats (Felis silvestris catus) and one fishing cat (Prionailurus viverrinus), cryopreserved in plastic freezing straws, and transferred into liquid nitrogen dry shippers for security screening. Treatment groups included frozen samples from each male scanned once or three times using a Transportation Security Administration-operated cabinet x-ray system, in addition to non-scanned samples (i.e., negative control) and samples previously scanned three times and exposed to five additional high-intensity x-ray bursts (i.e., positive control). Dosimeters placed in empty dry shippers were used to quantify radiation exposure. Following treatment, straws were thawed and spermatozoa analyzed for post-thaw motility (percentage motile and rate of progressive movement), acrosome status, and DNA integrity using single-cell gel electrophoresis (i.e., the comet assay). Dosimeter measurements determined that each airport screening procedure produced approximately 16 mrem of radiation exposure. Our results indicated that all levels of radiation exposure adversely affected (P < 0.05) post-thaw sperm motility, but the percentage of acrosome-intact spermatozoa did not differ (P > 0.05) among treatment groups. Results also showed that the amount of double-stranded DNA damage was greater (P < 0.05) in sperm samples from both cat species scanned three times compared to samples scanned once or negative controls. Findings suggest that new airport security measures may cause radiation-induced damage to

  7. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1977-04-05

    diversions. Perhaps the best evidence of the effectiveness of airline and airport security measures is the number of hijackings and related crimes prevented...airports. Consideration is being given to include a provision in the airport security regulation which would prohibit the introduction of...Security Program. A complete revision of the regulation that established basic airport security requirements is currently underway. One of the more

  8. 49 CFR 1542.303 - Security Directives and Information Circulars.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY... Information Circular to notify airport operators of security concerns. When TSA determines that additional... aviation, TSA issues a Security Directive setting forth mandatory measures. (b) Each airport operator must...

  9. 49 CFR 1542.303 - Security Directives and Information Circulars.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY... Information Circular to notify airport operators of security concerns. When TSA determines that additional... aviation, TSA issues a Security Directive setting forth mandatory measures. (b) Each airport operator must...

  10. 49 CFR 1542.303 - Security Directives and Information Circulars.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY... Information Circular to notify airport operators of security concerns. When TSA determines that additional... aviation, TSA issues a Security Directive setting forth mandatory measures. (b) Each airport operator must...

  11. 49 CFR 1542.303 - Security Directives and Information Circulars.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY... Information Circular to notify airport operators of security concerns. When TSA determines that additional... aviation, TSA issues a Security Directive setting forth mandatory measures. (b) Each airport operator must...

  12. Securing the Aviation Transportation System

    DTIC Science & Technology

    2007-12-01

    accessed 27 May 2007) 13 Robert W. Poole, Jr., “ Airport Security : Time for a New Model,” Reason Foundation online article, January 2006, Available from...15 Robert W. Poole, Jr., “ Airport Security : Time for a New Model,” Reason Foundation online article, January 2006...commercial jetliners. 24 Peter St. John, Air Piracy, Airport Security , and International Terrorism

  13. Identifying changing aviation threat environments within an adaptive Homeland Security Advisory System.

    PubMed

    Lee, Adrian J; Jacobson, Sheldon H

    2012-02-01

    A critical component of aviation security consists of screening passengers and baggage to protect airports and aircraft from terrorist threats. Advancements in screening device technology have increased the ability to detect these threats; however, specifying the operational configurations of these devices in response to changes in the threat environment can become difficult. This article proposes to use Fisher information as a statistical measure for detecting changes in the threat environment. The perceived risk of passengers, according to prescreening information and behavior analysis, is analyzed as the passengers sequentially enter the security checkpoint. The alarm responses from the devices used to detect threats are also analyzed to monitor significant changes in the frequency of threat items uncovered. The key results are that this information-based measure can be used within the Homeland Security Advisory System to indicate changes in threat conditions in real time, and provide the flexibility of security screening detection devices to responsively and automatically adapt operational configurations to these changing threat conditions. © 2012 Society for Risk Analysis. All rights reserved.

  14. Airport detection of implanted orthopedic devices.

    PubMed

    Ostrum, Robert F

    2006-10-01

    Since the attacks of September 11, 2001, the United States and other countries have increased airport security. Metal detectors (archway and handheld wand) are used to detect potentially dangerous instruments during airport screening. One consequence is that orthopedic implants are sometimes detected, and patients are detained and searched. The orthopedic literature is inconsistent in its reports on airport screening of patients with orthopedic implants. In this article, I review that literature and examine the factors that make detection of orthopedic implants a less than consistent science.

  15. Conducting Airport Anti-Terrorism Operations and Contingency Planning for Risk Reduction of the Terrorist Threat.

    DTIC Science & Technology

    1986-08-01

    victims of some of the most vicious terrorist acts occurring in the past year, airport security has come under increasing scrutiny by television...operations and contingency planning can be the weapons which airport security managers use to successfully battle the increasing trend of terrorist acts on airports today. (Author)

  16. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1981-04-15

    on item were processed through the screening system daily. The airline and airport security measures developed continue to provide increased safety...United States or Puerto Rico. None of these 16 hijackings resulted from insufficient airport security measures or a breakdown in the FAA-approved airport ... airport security programs is conducted at the Transportation Safety Institute in Oklahoma City, Oklahoma. The course provides in-depth coverage of civil

  17. Determining the Effectiveness Of Flexible Checkpoints

    DOT National Transportation Integrated Search

    2017-05-01

    Flexible checkpoints are sometimes referred to as phantom checkpoints, public awareness checkpoints, mobile awareness patrols, and mock checkpoints. This checkpoint strategy involves staging a checkpoint, but not actually staf...

  18. Toward an optimal online checkpoint solution under a two-level HPC checkpoint model

    DOE PAGES

    Di, Sheng; Robert, Yves; Vivien, Frederic; ...

    2016-03-29

    The traditional single-level checkpointing method suffers from significant overhead on large-scale platforms. Hence, multilevel checkpointing protocols have been studied extensively in recent years. The multilevel checkpoint approach allows different levels of checkpoints to be set (each with different checkpoint overheads and recovery abilities), in order to further improve the fault tolerance performance of extreme-scale HPC applications. How to optimize the checkpoint intervals for each level, however, is an extremely difficult problem. In this paper, we construct an easy-to-use two-level checkpoint model. Checkpoint level 1 deals with errors with low checkpoint/recovery overheads such as transient memory errors, while checkpoint level 2more » deals with hardware crashes such as node failures. Compared with previous optimization work, our new optimal checkpoint solution offers two improvements: (1) it is an online solution without requiring knowledge of the job length in advance, and (2) it shows that periodic patterns are optimal and determines the best pattern. We evaluate the proposed solution and compare it with the most up-to-date related approaches on an extreme-scale simulation testbed constructed based on a real HPC application execution. Simulation results show that our proposed solution outperforms other optimized solutions and can improve the performance significantly in some cases. Specifically, with the new solution the wall-clock time can be reduced by up to 25.3% over that of other state-of-the-art approaches. Lastly, a brute-force comparison with all possible patterns shows that our solution is always within 1% of the best pattern in the experiments.« less

  19. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1985-04-12

    other crimes against civil aviation prevented or deterred by airline and airport security procedures cannot be determined with certainty. However...were prevented from doing so by airline and airport security measures. As noted elsewhere in this report, 1,632 firearms were detected at screening...enforcement sQp:)t’ for airline and airport security measures. Finally, with the inc.asoDr of security costs in airline ticket prices, the passengers

  20. Three-dimensional imaging of hold baggage for airport security

    NASA Astrophysics Data System (ADS)

    Kolokytha, S.; Speller, R.; Robson, S.

    2014-06-01

    This study describes a cost-effective check-in baggage screening system, based on "on-belt tomosynthesis" (ObT) and close-range photogrammetry, that is designed to address the limitations of the most common system used, conventional projection radiography. The latter's limitations can lead to loss of information and an increase in baggage handling time, as baggage is manually searched or screened with more advanced systems. This project proposes a system that overcomes such limitations creating a cost-effective automated pseudo-3D imaging system, by combining x-ray and optical imaging to form digital tomograms. Tomographic reconstruction requires a knowledge of the change in geometry between multiple x-ray views of a common object. This is uniquely achieved using a close range photogrammetric system based on a small network of web-cameras. This paper presents the recent developments of the ObT system and describes recent findings of the photogrammetric system implementation. Based on these positive results, future work on the advancement of the ObT system as a cost-effective pseudo-3D imaging of hold baggage for airport security is proposed.

  1. Guidelines to improve airport preparedness against chemical and biological terrorism.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Edwards, Donna M.; Price, Phillip N.; Gordon, Susanna P.

    2005-05-01

    Guidelines to Improve Airport Preparedness Against Chemical and Biological Terrorism is a 100-page document that makes concrete recommendations on improving security and assessing vulnerable areas and helps its readers understand the nature of chemical and biological attacks. The report has been turned over to Airports Council International (ACI) and the American Association of Airport Executives (AAAE), two organizations that together represent the interests of thousands of airport personnel and facilities in the U.S. and around the world.

  2. 49 CFR 1544.231 - Airport-approved and exclusive area personnel identification systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Airport-approved and exclusive area personnel... AIRCRAFT OPERATOR SECURITY: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.231 Airport-approved... carry out a personnel identification system for identification media that are airport-approved, or...

  3. 49 CFR 1544.231 - Airport-approved and exclusive area personnel identification systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Airport-approved and exclusive area personnel... AIRCRAFT OPERATOR SECURITY: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.231 Airport-approved... carry out a personnel identification system for identification media that are airport-approved, or...

  4. 49 CFR 1544.231 - Airport-approved and exclusive area personnel identification systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Airport-approved and exclusive area personnel... AIRCRAFT OPERATOR SECURITY: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.231 Airport-approved... carry out a personnel identification system for identification media that are airport-approved, or...

  5. Compiler-assisted static checkpoint insertion

    NASA Technical Reports Server (NTRS)

    Long, Junsheng; Fuchs, W. K.; Abraham, Jacob A.

    1992-01-01

    This paper describes a compiler-assisted approach for static checkpoint insertion. Instead of fixing the checkpoint location before program execution, a compiler enhanced polling mechanism is utilized to maintain both the desired checkpoint intervals and reproducible checkpoint 1ocations. The technique has been implemented in a GNU CC compiler for Sun 3 and Sun 4 (Sparc) processors. Experiments demonstrate that the approach provides for stable checkpoint intervals and reproducible checkpoint placements with performance overhead comparable to a previously presented compiler assisted dynamic scheme (CATCH) utilizing the system clock.

  6. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1977-10-31

    searches. Perhaps the best evidence of the effectiveness of airline and airport security measures is the number of hijackings and related crimes...revision of the regulation that established basic airport security requirements is currently underway. One of the more significant revisions under study... airport security procedures cannot be determined with certainty. Nowever, the number of firearms detected at passenger screening points under suspicious

  7. Semiannual Report to Congress on the Effectiveness of the Civil Aviation Security Program

    DTIC Science & Technology

    1988-11-01

    secure Zround environment and for providing local law enforcement support for airline and airport security measures. Finally, the passengers, the...operating environment for these air carriers. Airport security programs are designed to meet the threat to the specific airport. Of the 402 airports...assistance during this project. Responding to urgent requests from the Government of Liberia for onsite training of its airport security forces, FAA

  8. Semiannual Report to Congress on the Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1987-12-31

    This report also provides data on the initiatives being implemented as a result of the review of domestic airport security by the Secretary’s Safety...enforcement support for airline and airport security measures. Finally, the passengers-the ultimate beneficiaries of the security program--pay for...of these airports is required to implement a security program which provides a secure operating environment for these air carriers. Airport security programs

  9. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1978-10-12

    passengers and over one million pieces of carry-on baggage daily. A major revision of the regulation that established basic airport security requirements...Crimes- Prevented - The number of hijacking attempts or other crimes against civil aviation prevented or deterred by airline and airport security procedures...from doing so by airline and airport security procedures. This makes a total of 74 possible hijackings or related crimes that may have been prevented

  10. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1975-10-06

    Results of the passenger screening procedures continue to reflect the success and effec- tiveness of airline and airport security programs. During the...airline and airport security programs. While it is impossible to estimate accurately just how many hijackings and related crimes were prevented, the...attempts might have occurred during 1974 and as many as 25 during the first 6 months of 1975, if current airline and airport security programs had not

  11. Semiannual Report to Congress on the Effectiveness of the Civil Aviation Security Program

    DTIC Science & Technology

    1991-02-01

    enforcement support for airline and airport security measures. Airline passengers, as the ultimate beneficiaries of the security program. pay for the...environment for these air carriers. Airport security programs are designed to meet the threat to the specific airport. Of the 4(02 airports. 18...essential to many passengers. " FAA is currently reviewing Parts 107 and 108 of the Federal Aviation Regulations, covering airport security and airplane

  12. Recovery from the DNA Replication Checkpoint

    PubMed Central

    Chaudhury, Indrajit; Koepp, Deanna M.

    2016-01-01

    Checkpoint recovery is integral to a successful checkpoint response. Checkpoint pathways monitor progress during cell division so that in the event of an error, the checkpoint is activated to block the cell cycle and activate repair pathways. Intrinsic to this process is that once repair has been achieved, the checkpoint signaling pathway is inactivated and cell cycle progression resumes. We use the term “checkpoint recovery” to describe the pathways responsible for the inactivation of checkpoint signaling and cell cycle re-entry after the initial stress has been alleviated. The DNA replication or S-phase checkpoint monitors the integrity of DNA synthesis. When replication stress is encountered, replication forks are stalled, and the checkpoint signaling pathway is activated. Central to recovery from the S-phase checkpoint is the restart of stalled replication forks. If checkpoint recovery fails, stalled forks may become unstable and lead to DNA breaks or unusual DNA structures that are difficult to resolve, causing genomic instability. Alternatively, if cell cycle resumption mechanisms become uncoupled from checkpoint inactivation, cells with under-replicated DNA might proceed through the cell cycle, also diminishing genomic stability. In this review, we discuss the molecular mechanisms that contribute to inactivation of the S-phase checkpoint signaling pathway and the restart of replication forks during recovery from replication stress. PMID:27801838

  13. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1976-09-20

    commerce--a pr per balance appears to exist. Moreover, airline and airport security programs appear to be capable of responding to changes in the nature...Moreover, airline and airport security programs appear to be capable of responding to changes in the nature and level of current and future threats. The...delays and diversions were experienced. Airline and airport security measures continued to afford the necessary level of protection to U.S. air

  14. Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1979-04-25

    the airline and airport security measures in effect. Moreover, of the 25 U.S. airline hijackings that occurred over this 6-year period, none was caused...Furthermore, it is estimated that 75 hijackings or related crimes may have been prevented by the airline and airport security measures in effect...system. Moreover, it is estimated that at least 75 hijackings or related crimes may have been prevented by U.S. airline and airport security measures

  15. Border and Transportation Security: Possible New Directions and Policy Options

    DTIC Science & Technology

    2005-03-29

    Security: Overview of Issues. See also “ JFK Airport to Receive Walk-Through Explosives Detection Portal,” Homeland Security Monitor, Oct. 26, 2004. In...of integrated security design can be seen at Terminal six at the JFK airport in New York City. Since many airports were originally designed in the

  16. Implementing Solar Technologies at Airports

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kandt, A.; Romero, R.

    2014-07-01

    Federal agencies, such as the Department of Defense and Department of Homeland Security, as well as numerous private entities are actively pursuing the installation of solar technologies to help reduce fossil fuel energy use and associated emissions, meet sustainability goals, and create more robust or reliable operations. One potential approach identified for siting solar technologies is the installation of solar energy technologies at airports and airfields, which present a significant opportunity for hosting solar technologies due to large amounts of open land. This report focuses largely on the Federal Aviation Administration's (FAA's) policies toward siting solar technologies at airports.

  17. 8 CFR 234.4 - International airports for entry of aliens.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false International airports for entry of aliens. 234.4 Section 234.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS DESIGNATION OF PORTS OF ENTRY FOR ALIENS ARRIVING BY CIVIL AIRCRAFT § 234.4 International airports for entry...

  18. 8 CFR 234.4 - International airports for entry of aliens.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false International airports for entry of aliens. 234.4 Section 234.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS DESIGNATION OF PORTS OF ENTRY FOR ALIENS ARRIVING BY CIVIL AIRCRAFT § 234.4 International airports for entry...

  19. 8 CFR 234.4 - International airports for entry of aliens.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false International airports for entry of aliens. 234.4 Section 234.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS DESIGNATION OF PORTS OF ENTRY FOR ALIENS ARRIVING BY CIVIL AIRCRAFT § 234.4 International airports for entry...

  20. 8 CFR 234.4 - International airports for entry of aliens.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false International airports for entry of aliens. 234.4 Section 234.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS DESIGNATION OF PORTS OF ENTRY FOR ALIENS ARRIVING BY CIVIL AIRCRAFT § 234.4 International airports for entry...

  1. 8 CFR 234.4 - International airports for entry of aliens.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false International airports for entry of aliens. 234.4 Section 234.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS DESIGNATION OF PORTS OF ENTRY FOR ALIENS ARRIVING BY CIVIL AIRCRAFT § 234.4 International airports for entry...

  2. Airport Surface Network Architecture Definition

    NASA Technical Reports Server (NTRS)

    Nguyen, Thanh C.; Eddy, Wesley M.; Bretmersky, Steven C.; Lawas-Grodek, Fran; Ellis, Brenda L.

    2006-01-01

    Currently, airport surface communications are fragmented across multiple types of systems. These communication systems for airport operations at most airports today are based dedicated and separate architectures that cannot support system-wide interoperability and information sharing. The requirements placed upon the Communications, Navigation, and Surveillance (CNS) systems in airports are rapidly growing and integration is urgently needed if the future vision of the National Airspace System (NAS) and the Next Generation Air Transportation System (NGATS) 2025 concept are to be realized. To address this and other problems such as airport surface congestion, the Space Based Technologies Project s Surface ICNS Network Architecture team at NASA Glenn Research Center has assessed airport surface communications requirements, analyzed existing and future surface applications, and defined a set of architecture functions that will help design a scalable, reliable and flexible surface network architecture to meet the current and future needs of airport operations. This paper describes the systems approach or methodology to networking that was employed to assess airport surface communications requirements, analyze applications, and to define the surface network architecture functions as the building blocks or components of the network. The systems approach used for defining these functions is relatively new to networking. It is viewing the surface network, along with its environment (everything that the surface network interacts with or impacts), as a system. Associated with this system are sets of services that are offered by the network to the rest of the system. Therefore, the surface network is considered as part of the larger system (such as the NAS), with interactions and dependencies between the surface network and its users, applications, and devices. The surface network architecture includes components such as addressing/routing, network management, network

  3. 77 FR 64819 - New Agency Information Collection Activity Under OMB Review: Office of Law Enforcement/Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ...This notice announces that the Transportation Security Administration (TSA) has forwarded the new Information Collection Request (ICR) abstracted below to the Office of Management and Budget (OMB) for review and approval under the Paperwork Reduction Act (PRA). The ICR describes the nature of the information collection and its expected burden. TSA published a Federal Register notice, with a 60-day comment period soliciting comments, of the following collection of information on June 20, 2012, 77 FR 37062. The collection involves the reimbursement of expenses incurred by airport operators for the provision of law enforcement officers (LEOs) to support airport security checkpoint screening.

  4. Inguinal hernia and airport scanners: an emerging indication for repair?

    PubMed

    Naraynsingh, Vijay; Cawich, Shamir O; Maharaj, Ravi; Dan, Dilip

    2013-01-01

    The use of advanced imaging technology at international airports is increasing in popularity as a corollary to heightened security concerns across the globe. Operators of airport scanners should be educated about common medical disorders such as inguinal herniae in order to avoid unnecessary harassment of travelers since they will encounter these with increasing frequency.

  5. A Cross-Sectional Study of Tobacco Advertising, Promotion, and Sponsorship in Airports across Europe and the United States

    PubMed Central

    Soong, Andrea; Navas-Acien, Ana; Pang, Yuanjie; Lopez, Maria Jose; Garcia-Esquinas, Esther; Stillman, Frances A.

    2016-01-01

    Tobacco advertising, promotion, and sponsorship (TAPS) bans are effective and are increasingly being implemented in a number of venues and countries, yet the state of TAPS in airports and their effect on airport smoking behavior is unknown. The objective of this study was to evaluate the presence of TAPS in airports across Europe and the US, and to begin to examine the relationship between TAPS and smoking behaviors in airports. We used a cross-sectional study design to observe 21 airports in Europe (11) and the US (10). Data collectors observed points of sale for tobacco products, types of products sold, advertisements and promotions, and branding or logos that appeared in the airport. Tobacco products were sold in 95% of all airports, with significantly more sales in Europe than the US. Advertisements appeared mostly in post-security areas; however, airports with advertisements in pre-security areas had significantly more smokers observed outdoors than airports without advertisements in pre-security areas. Tobacco branding appeared in designated smoking rooms as well as on non-tobacco products in duty free shops. TAPS are widespread in airports in Europe and the US and might be associated with outdoor smoking, though further research is needed to better understand any relationship between the two. This study adds to a growing body of research on tobacco control in air transit and related issues. As smoke-free policies advance, they should include comprehensive TAPS bans that extend to airport facilities. PMID:27690072

  6. A Cross-Sectional Study of Tobacco Advertising, Promotion, and Sponsorship in Airports across Europe and the United States.

    PubMed

    Soong, Andrea; Navas-Acien, Ana; Pang, Yuanjie; Lopez, Maria Jose; Garcia-Esquinas, Esther; Stillman, Frances A

    2016-09-28

    Tobacco advertising, promotion, and sponsorship (TAPS) bans are effective and are increasingly being implemented in a number of venues and countries, yet the state of TAPS in airports and their effect on airport smoking behavior is unknown. The objective of this study was to evaluate the presence of TAPS in airports across Europe and the US, and to begin to examine the relationship between TAPS and smoking behaviors in airports. We used a cross-sectional study design to observe 21 airports in Europe (11) and the US (10). Data collectors observed points of sale for tobacco products, types of products sold, advertisements and promotions, and branding or logos that appeared in the airport. Tobacco products were sold in 95% of all airports, with significantly more sales in Europe than the US. Advertisements appeared mostly in post-security areas; however, airports with advertisements in pre-security areas had significantly more smokers observed outdoors than airports without advertisements in pre-security areas. Tobacco branding appeared in designated smoking rooms as well as on non-tobacco products in duty free shops. TAPS are widespread in airports in Europe and the US and might be associated with outdoor smoking, though further research is needed to better understand any relationship between the two. This study adds to a growing body of research on tobacco control in air transit and related issues. As smoke-free policies advance, they should include comprehensive TAPS bans that extend to airport facilities.

  7. Detection of orthopaedic implants by airport metal detectors.

    PubMed

    Abbassian, Ali; Datla, Balarama; Brooks, R A

    2007-04-01

    We performed a questionnaire study to establish the frequency and consequences of the detection of orthopaedic implants by airport security and to help us advise patients correctly. All published literature on this subject is based on experimental studies and no 'real-life' data are available. A total of 200 patients with a variety of implants were identified. All patients were sent a postal questionnaire enquiring about their experience with airport security since their surgery. Of the cohort, 154 (77%) patients responded. About half of the implants (47%) were detected, but the majority of patients (72%) were not significantly inconvenienced. When detected, only 9% of patients were asked for documentary evidence of their implant. We also found that patients with a total knee replacement (TKR) had a greater chance of detection as compared to those with a total hip replacement (THR; 71% versus 31%; P = 0.03). All patients, and in particular those with a TKR, can be re-assured that, although they have a fair chance of detection by airport security, a major disruption to their journey is unlikely. We advise that documentation to prove the presence of an orthopaedic implant should be offered to those who are concerned about the potential for inconvenience, but such documentation is not required routinely.

  8. Investigative Operations: Use of Covert Testing to Identify Security Vulnerabilities and Fraud, Waste, and Abuse

    DTIC Science & Technology

    2007-11-14

    including evaluations of controls over radioactive materials and security at America’s borders, airport security , sales of sensitive and surplus...officers. The details of this March 2006 report are classified; however, TSA has authorized this limited discussion. Airport Security Testing Sale of...of covert security vulnerability testing of numerous airports across the country. During these covert tests, our investigators passed through airport

  9. Inguinal Hernia and Airport Scanners: An Emerging Indication for Repair?

    PubMed Central

    Cawich, Shamir O.; Maharaj, Ravi; Dan, Dilip

    2013-01-01

    The use of advanced imaging technology at international airports is increasing in popularity as a corollary to heightened security concerns across the globe. Operators of airport scanners should be educated about common medical disorders such as inguinal herniae in order to avoid unnecessary harassment of travelers since they will encounter these with increasing frequency. PMID:24368923

  10. 49 CFR 1542.203 - Security of the air operations area (AOA).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.203 Security of the air operations area (AOA). (a) Each airport operator required to have a... 49 Transportation 9 2013-10-01 2013-10-01 false Security of the air operations area (AOA). 1542...

  11. 49 CFR 1542.203 - Security of the air operations area (AOA).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.203 Security of the air operations area (AOA). (a) Each airport operator required to have a... 49 Transportation 9 2010-10-01 2010-10-01 false Security of the air operations area (AOA). 1542...

  12. 49 CFR 1542.203 - Security of the air operations area (AOA).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.203 Security of the air operations area (AOA). (a) Each airport operator required to have a... 49 Transportation 9 2011-10-01 2011-10-01 false Security of the air operations area (AOA). 1542...

  13. 49 CFR 1542.203 - Security of the air operations area (AOA).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.203 Security of the air operations area (AOA). (a) Each airport operator required to have a... 49 Transportation 9 2012-10-01 2012-10-01 false Security of the air operations area (AOA). 1542...

  14. 49 CFR 1542.203 - Security of the air operations area (AOA).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.203 Security of the air operations area (AOA). (a) Each airport operator required to have a... 49 Transportation 9 2014-10-01 2014-10-01 false Security of the air operations area (AOA). 1542...

  15. Checkpointing for a hybrid computing node

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cher, Chen-Yong

    2016-03-08

    According to an aspect, a method for checkpointing in a hybrid computing node includes executing a task in a processing accelerator of the hybrid computing node. A checkpoint is created in a local memory of the processing accelerator. The checkpoint includes state data to restart execution of the task in the processing accelerator upon a restart operation. Execution of the task is resumed in the processing accelerator after creating the checkpoint. The state data of the checkpoint are transferred from the processing accelerator to a main processor of the hybrid computing node while the processing accelerator is executing the task.

  16. English for Airport Ground Staff

    ERIC Educational Resources Information Center

    Cutting, Joan

    2012-01-01

    This article describes part of a European Commission Leonardo project that aimed to design a multimedia course for English language learners seeking work as ground staff in European airports. The structural-functional analysis of the dialogues written from the course showed that, across the four trades explored (security guards, ground handlers,…

  17. The impact of joint responses of devices in an airport security system.

    PubMed

    Nie, Xiaofeng; Batta, Rajan; Drury, Colin G; Lin, Li

    2009-02-01

    In this article, we consider a model for an airport security system in which the declaration of a threat is based on the joint responses of inspection devices. This is in contrast to the typical system in which each check station independently declares a passenger as having a threat or not having a threat. In our framework the declaration of threat/no-threat is based upon the passenger scores at the check stations he/she goes through. To do this we use concepts from classification theory in the field of multivariate statistics analysis and focus on the main objective of minimizing the expected cost of misclassification. The corresponding correct classification and misclassification probabilities can be obtained by using a simulation-based method. After computing the overall false alarm and false clear probabilities, we compare our joint response system with two other independently operated systems. A model that groups passengers in a manner that minimizes the false alarm probability while maintaining the false clear probability within specifications set by a security authority is considered. We also analyze the staffing needs at each check station for such an inspection scheme. An illustrative example is provided along with sensitivity analysis on key model parameters. A discussion is provided on some implementation issues, on the various assumptions made in the analysis, and on potential drawbacks of the approach.

  18. Reducing space overhead for independendent checkpointing

    NASA Technical Reports Server (NTRS)

    Wang, Yi-Min; Chung, Pi-Yu; Lin, In-Jen; Fuchs, W. Kent

    1992-01-01

    The main disadvantages of independent checkpointing are the possible domino effect and the associated storage space overhead for maintaining multiple checkpoints. In most previous work, it has been assumed that only the checkpoints older than the current global recovery line can be discarded. Here, we generalize a notion of recovery line to potential recovery line. Only the checkpoints belonging to at least one of the potential recovery lines cannot be discarded. By using the model of maximum-sized antichains on a partially ordered set, an efficient algorithm is developed for finding all non-discardable checkpoints, and we show that the number of non-discardable checkpoints cannot exceed N(N+1)/2, where N is the number of processors. Communication trace driven simulation for several hypercube programs is performed to show the benefit of the proposed algorithm for real applications.

  19. Detection of Orthopaedic Implants by Airport Metal Detectors

    PubMed Central

    Abbassian, Ali; Datla, Balarama; Brooks, RA

    2007-01-01

    INTRODUCTION We performed a questionnaire study to establish the frequency and consequences of the detection of orthopaedic implants by airport security and to help us advise patients correctly. All published literature on this subject is based on experimental studies and no ‘real-life’ data are available. PATIENTS AND METHODS A total of 200 patients with a variety of implants were identified. All patients were sent a postal questionnaire enquiring about their experience with airport security since their surgery. RESULTS Of the cohort, 154 (77%) patients responded. About half of the implants (47%) were detected, but the majority of patients (72%) were not significantly inconvenienced. When detected, only 9% of patients were asked for documentary evidence of their implant. We also found that patients with a total knee replacement (TKR) had a greater chance of detection as compared to those with a total hip replacement (THR; 71% versus 31%; P = 0.03). CONCLUSIONS All patients, and in particular those with a TKR, can be re-assured that, although they have a fair chance of detection by airport security, a major disruption to their journey is unlikely. We advise that documentation to prove the presence of an orthopaedic implant should be offered to those who are concerned about the potential for inconvenience, but such documentation is not required routinely. PMID:17394716

  20. Transportation Security Administration in Defense of the National Aviation Infrastructure

    DTIC Science & Technology

    2009-02-12

    evidence suggests a hole exists within our airport security process. That hole may be caused by an over-reliance on technology and a blatant disregard of...environment enables BDOs to operate with increased effectiveness.11 Technology. Three major tools sit at the airport security technology forefront...Through Covert Testing of TSA’s Passenger Screening Process, GAO‐08‐48T, 15 Nov 07, 2. 16 Orlando News, “TSA Workers Skipping Orlando Airport Security Causes

  1. Aeronautical Mobile Airport Communications System (AeroMACS)

    NASA Technical Reports Server (NTRS)

    Budinger, James M.; Hall, Edward

    2011-01-01

    To help increase the capacity and efficiency of the nation s airports, a secure wideband wireless communications system is proposed for use on the airport surface. This paper provides an overview of the research and development process for the Aeronautical Mobile Airport Communications System (AeroMACS). AeroMACS is based on a specific commercial profile of the Institute of Electrical and Electronics Engineers (IEEE) 802.16 standard known as Wireless Worldwide Interoperability for Microwave Access or WiMAX (WiMax Forum). The paper includes background on the need for global interoperability in air/ground data communications, describes potential AeroMACS applications, addresses allocated frequency spectrum constraints, summarizes the international standardization process, and provides findings and recommendations from the world s first AeroMACS prototype implemented in Cleveland, Ohio, USA.

  2. Final Report to President Clinton: White House Commission on Aviation Safety and Security

    DTIC Science & Technology

    1997-02-12

    nationwide non-profit security corporation, funded by the airlines, to handle airport security . This concept, under consideration by the major...Canines are used to detect explosives in many important areas, but only sparingly in airport security . The Commission is convinced that an increase in...testing should also be increased by the FAA, and incorporated as a regular part of airport security action plans. Frequent, sophisticated attempts by

  3. Lazy checkpoint coordination for bounding rollback propagation

    NASA Technical Reports Server (NTRS)

    Wang, Yi-Min; Fuchs, W. Kent

    1992-01-01

    Independent checkpointing allows maximum process autonomy but suffers from potential domino effects. Coordinated checkpointing eliminates the domino effect by sacrificing a certain degree of process autonomy. In this paper, we propose the technique of lazy checkpoint coordination which preserves process autonomy while employing communication-induced checkpoint coordination for bounding rollback propagation. The introduction of the notion of laziness allows a flexible trade-off between the cost for checkpoint coordination and the average rollback distance. Worst-case overhead analysis provides a means for estimating the extra checkpoint overhead. Communication trace-driven simulation for several parallel programs is used to evaluate the benefits of the proposed scheme for real applications.

  4. Non-volatile memory for checkpoint storage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blumrich, Matthias A.; Chen, Dong; Cipolla, Thomas M.

    A system, method and computer program product for supporting system initiated checkpoints in high performance parallel computing systems and storing of checkpoint data to a non-volatile memory storage device. The system and method generates selective control signals to perform checkpointing of system related data in presence of messaging activity associated with a user application running at the node. The checkpointing is initiated by the system such that checkpoint data of a plurality of network nodes may be obtained even in the presence of user applications running on highly parallel computers that include ongoing user messaging activity. In one embodiment, themore » non-volatile memory is a pluggable flash memory card.« less

  5. Network support for system initiated checkpoints

    DOEpatents

    Chen, Dong; Heidelberger, Philip

    2013-01-29

    A system, method and computer program product for supporting system initiated checkpoints in parallel computing systems. The system and method generates selective control signals to perform checkpointing of system related data in presence of messaging activity associated with a user application running at the node. The checkpointing is initiated by the system such that checkpoint data of a plurality of network nodes may be obtained even in the presence of user applications running on highly parallel computers that include ongoing user messaging activity.

  6. Checkpointing in speculative versioning caches

    DOEpatents

    Eichenberger, Alexandre E; Gara, Alan; Gschwind, Michael K; Ohmacht, Martin

    2013-08-27

    Mechanisms for generating checkpoints in a speculative versioning cache of a data processing system are provided. The mechanisms execute code within the data processing system, wherein the code accesses cache lines in the speculative versioning cache. The mechanisms further determine whether a first condition occurs indicating a need to generate a checkpoint in the speculative versioning cache. The checkpoint is a speculative cache line which is made non-speculative in response to a second condition occurring that requires a roll-back of changes to a cache line corresponding to the speculative cache line. The mechanisms also generate the checkpoint in the speculative versioning cache in response to a determination that the first condition has occurred.

  7. 48 CFR 3036.570 - Special precautions for work at operating airports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Special precautions for work at operating airports. 3036.570 Section 3036.570 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY ACQUISITION REGULATION (HSAR) SPECIAL CATEGORIES OF...

  8. DNA damage checkpoint recovery and cancer development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Haiyong; Zhang, Xiaoshan; Teng, Lisong, E-mail: lsteng@zju.edu.cn

    2015-06-10

    Cell cycle checkpoints were initially presumed to function as a regulator of cell cycle machinery in response to different genotoxic stresses, and later found to play an important role in the process of tumorigenesis by acting as a guard against DNA over-replication. As a counterpart of checkpoint activation, the checkpoint recovery machinery is working in opposition, aiming to reverse the checkpoint activation and resume the normal cell cycle. The DNA damage response (DDR) and oncogene induced senescence (OIS) are frequently found in precancerous lesions, and believed to constitute a barrier to tumorigenesis, however, the DDR and OIS have been observedmore » to be diminished in advanced cancers of most tissue origins. These findings suggest that when progressing from pre-neoplastic lesions to cancer, DNA damage checkpoint barriers are overridden. How the DDR checkpoint is bypassed in this process remains largely unknown. Activated cytokine and growth factor-signaling pathways were very recently shown to suppress the DDR and to promote uncontrolled cell proliferation in the context of oncovirus infection. In recent decades, data from cell line and tumor models showed that a group of checkpoint recovery proteins function in promoting tumor progression; data from patient samples also showed overexpression of checkpoint recovery proteins in human cancer tissues and a correlation with patients' poor prognosis. In this review, the known cell cycle checkpoint recovery proteins and their roles in DNA damage checkpoint recovery are reviewed, as well as their implications in cancer development. This review also provides insight into the mechanism by which the DDR suppresses oncogene-driven tumorigenesis and tumor progression. - Highlights: • DNA damage checkpoint works as a barrier to cancer initiation. • DDR machinary response to genotoxic and oncogenic stress in similar way. • Checkpoint recovery pathways provide active signaling in cell cycle control.

  9. HOMELAND SECURITY: Challenges and Strategies in Addressing Short- and Long-Term National Needs

    DTIC Science & Technology

    2001-11-07

    air travel has already prompted attention to chronic problems with airport security that we and others have been pointing to for years. Moreover, the...capital for certain areas such as intelligence, public health and airport security will also be necessary as well to foster and maintain the skill...Weaknesses in Airport Security and Options for Assigning Screening Responsibilities, (GAO-01-1165T, Sept. 21, 2001). Aviation Security: Terrorist Acts

  10. Convenient Airports: Point of View of the Passengers

    NASA Technical Reports Server (NTRS)

    Magri, Adival Aparecido, Jr.; Alves, Claudio Jorge Pinto

    2003-01-01

    The competition among airlines or among airports aiming at to increase the demand for its services has been more and more incited. Knowledge the perception of the users for the offered services means to meet the customer's needs and expectations in order either to keep the customer, and therefore keep a significant advantage over competitors. The passenger of the air transportation wants rapidity, security and convenience. Convenience can be translated by comfort that the passenger wants for the price that he can pay. In this paper had been identified. as a result of a survey achieved in six Brazilian airports during 2002, the best indicators in the passenger's perception. These indicators among any others were listed m the handbook of Airports Council International (ACI). Distinctive perceptions were observed among passengers with different travel motivations. This survey had been carried through in the airports of Brasilia, Porto Alegre, Salvador. Fortaleza, Curitiba and Bel6m. Considering this survey we can identified the most attractive airport among them. This work is a way to help improve quality of service, in particular, m these six airports of the Brazilian network. The results should be published and made available to all the parties concerned (airport authority, airlines and service providers) and should lead to corrective action when the passenger is not satisfied with the service.

  11. 76 FR 70468 - Extension of Agency Information Collection Activity Under OMB Review: Airport Security

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ... (SIDA); (4) submission to TSA of identifying information about individuals to whom the airport operator... information on individuals with unescorted access to a SIDA. Airport operators must ensure that individuals...

  12. Productivity Analysis of Public and Private Airports: A Causal Investigation

    NASA Technical Reports Server (NTRS)

    Vasigh, Bijan; Gorjidooz, Javad

    2007-01-01

    Around the world, airports are being viewed as enterprises, rather than public services, which are expected to be managed efficiently and provide passengers with courteous customer services. Governments are, increasingly, turning to the private sectors for their efficiency in managing the operation, financing, and development, as well as providing security for airports. Operational and financial performance evaluation has become increasingly important to airport operators due to recent trends in airport privatization. Assessing performance allows the airport operators to plan for human resources and capital investment as efficiently as possible. Productivity measurements may be used as comparisons and guidelines in strategic planning, in the internal analysis of operational efficiency and effectiveness, and in assessing the competitive position of an airport in transportation industry. The primary purpose of this paper is to investigate the operational and financial efficiencies of 22 major airports in the United States and Europe. These airports are divided into three groups based on private ownership (7 British Airport Authority airports), public ownership (8 major United States airports), and a mix of private and public ownership (7 major European Union airports. The detail ownership structures of these airports are presented in Appendix A. Total factor productivity (TFP) model was utilized to measure airport performance in terms of financial and operational efficiencies and to develop a benchmarking tool to identify the areas of strength and weakness. A regression model was then employed to measure the relationship between TFP and ownership structure. Finally a Granger causality test was performed to determine whether ownership structure is a Granger cause of TFP. The results of the analysis presented in this paper demonstrate that there is not a significant relationship between airport TFP and ownership structure. Airport productivity and efficiency is

  13. 49 CFR 1548.11 - Training and knowledge for individuals with security-related duties.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...; (2) Applicable Security Directives and Information Circulars; (3) The approved airport security... Directives and Information Circulars; (4) The approved airport security program(s) applicable to their... security-related duties. 1548.11 Section 1548.11 Transportation Other Regulations Relating to...

  14. 49 CFR 1548.11 - Training and knowledge for individuals with security-related duties.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...; (2) Applicable Security Directives and Information Circulars; (3) The approved airport security... Directives and Information Circulars; (4) The approved airport security program(s) applicable to their... security-related duties. 1548.11 Section 1548.11 Transportation Other Regulations Relating to...

  15. 49 CFR 1548.11 - Training and knowledge for individuals with security-related duties.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...; (2) Applicable Security Directives and Information Circulars; (3) The approved airport security... Directives and Information Circulars; (4) The approved airport security program(s) applicable to their... security-related duties. 1548.11 Section 1548.11 Transportation Other Regulations Relating to...

  16. 49 CFR 1548.11 - Training and knowledge for individuals with security-related duties.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...; (2) Applicable Security Directives and Information Circulars; (3) The approved airport security... Directives and Information Circulars; (4) The approved airport security program(s) applicable to their... security-related duties. 1548.11 Section 1548.11 Transportation Other Regulations Relating to...

  17. 49 CFR 1542.205 - Security of the security identification display area (SIDA).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... area (SIDA). 1542.205 Section 1542.205 Transportation Other Regulations Relating to Transportation... AIRPORT SECURITY Operations § 1542.205 Security of the security identification display area (SIDA). (a... one SIDA, as follows: (1) Each secured area must be a SIDA. (2) Each part of the air operations area...

  18. 49 CFR 1542.205 - Security of the security identification display area (SIDA).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... area (SIDA). 1542.205 Section 1542.205 Transportation Other Regulations Relating to Transportation... AIRPORT SECURITY Operations § 1542.205 Security of the security identification display area (SIDA). (a... one SIDA, as follows: (1) Each secured area must be a SIDA. (2) Each part of the air operations area...

  19. 49 CFR 1542.205 - Security of the security identification display area (SIDA).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... area (SIDA). 1542.205 Section 1542.205 Transportation Other Regulations Relating to Transportation... AIRPORT SECURITY Operations § 1542.205 Security of the security identification display area (SIDA). (a... one SIDA, as follows: (1) Each secured area must be a SIDA. (2) Each part of the air operations area...

  20. 49 CFR 1542.205 - Security of the security identification display area (SIDA).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... area (SIDA). 1542.205 Section 1542.205 Transportation Other Regulations Relating to Transportation... AIRPORT SECURITY Operations § 1542.205 Security of the security identification display area (SIDA). (a... one SIDA, as follows: (1) Each secured area must be a SIDA. (2) Each part of the air operations area...

  1. 49 CFR 1542.205 - Security of the security identification display area (SIDA).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... area (SIDA). 1542.205 Section 1542.205 Transportation Other Regulations Relating to Transportation... AIRPORT SECURITY Operations § 1542.205 Security of the security identification display area (SIDA). (a... one SIDA, as follows: (1) Each secured area must be a SIDA. (2) Each part of the air operations area...

  2. Automation in airport security X-ray screening of cabin baggage: Examining benefits and possible implementations of automated explosives detection.

    PubMed

    Hättenschwiler, Nicole; Sterchi, Yanik; Mendes, Marcia; Schwaninger, Adrian

    2018-10-01

    Bomb attacks on civil aviation make detecting improvised explosive devices and explosive material in passenger baggage a major concern. In the last few years, explosive detection systems for cabin baggage screening (EDSCB) have become available. Although used by a number of airports, most countries have not yet implemented these systems on a wide scale. We investigated the benefits of EDSCB with two different levels of automation currently being discussed by regulators and airport operators: automation as a diagnostic aid with an on-screen alarm resolution by the airport security officer (screener) or EDSCB with an automated decision by the machine. The two experiments reported here tested and compared both scenarios and a condition without automation as baseline. Participants were screeners at two international airports who differed in both years of work experience and familiarity with automation aids. Results showed that experienced screeners were good at detecting improvised explosive devices even without EDSCB. EDSCB increased only their detection of bare explosives. In contrast, screeners with less experience (tenure < 1 year) benefitted substantially from EDSCB in detecting both improvised explosive devices and bare explosives. A comparison of all three conditions showed that automated decision provided better human-machine detection performance than on-screen alarm resolution and no automation. This came at the cost of slightly higher false alarm rates on the human-machine system level, which would still be acceptable from an operational point of view. Results indicate that a wide-scale implementation of EDSCB would increase the detection of explosives in passenger bags and automated decision instead of automation as diagnostic aid with on screen alarm resolution should be considered. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

  3. Hydrogen applications for Lambert-St. Louis International Airport

    DOT National Transportation Integrated Search

    2009-01-01

    Today, major airports are facing challenges related to pollution, energy efficiency, and safety and security. Hydrogen and fuel cell technologies, regarded as one of the key energy solutions of the 21st century are more energy efficient and reliable ...

  4. The Correlations between Airport Sustainability and Indonesian Economic Growth

    NASA Astrophysics Data System (ADS)

    Setiawan, M. I.; Dhaniarti, I.; Utomo, W. M.; Sukoco, A.; Mudjanarko, S. W.; Hasyim, C.; Prasetijo, J.; Kurniasih, N.; Wajdi, M. B. N.; Purworusmiardi, T.; Suyono, J.; Sudapet, I. N.; Nasihien, R. D.; Wulandari, D. A. R.; Ade, R. T.; Atmaja, W. M. T.; Sugeng; Wulandari, A.

    2018-04-01

    This study aims to analyze the correlation between airport performances with Gross domestic product-regional (GDP-regional) performance. This research uses quantitative research method with correlation study approach. Based on the T-Value Test Result, the T-value for the Airport Performance variable is 14,264. T-Value Test Results and compared with T-table equal to 1,976 (significant level 0,05) hence T-count> T-table so variable of Airport Perform predicted have significant correlation to GDP-regional. This means that good airport performance will either improve the performance of Water supply, Sewerage, Waste Management and Remediation Activities; Wholesale and Retail Trade; Repair of Motor Vehicles and Motorcycles; Accommodation and Food Service Activities; Financial and Insurance Activities; Business Activities; Public Administration and Defence; Compulsory Social Security; Education; Human Health and Social Work Activities; Other Services Activities; Manufacturing; and Electricity and Gas, better.

  5. Airport Catchment Area- Example Warsaw Modlin Airport

    NASA Astrophysics Data System (ADS)

    Błachut, Jakub

    2017-10-01

    The form and functions of airports change over time, just like the form and function of cities. Historically, airports are understood as places of aircraft landing, control towers operation and location of other facilities used for communication and transport. This traditional model is giving way to the concept of so-called Airport Cities, based on the assumption that, in addition to its infrastructure and air services, also non-air services are performed, constituting a source of income. At the same time, their reach and impact on the economy of the areas around the airport are expanding. Idea City Airport appeared in the United States in the late twentieth century. The author is J. D. Kasarda, he believes that it is around these big air ports that airport cities develop. In the world, there are currently 45 areas which can be classified in this category, out of which 12 are located in Europe. Main air traffic hubs in Europe are not only the most important passenger traffic junctions, but also largest centres dispatching goods (cargo). It can be said that, among the 30 largest airports, 24 are the largest in terms of both passenger and freight traffic. These airports cover up to 89.9% of the total freight transport of all European airports. At the same time, they serve 56.9% of all passengers in Europe. Based on the concept of Airport City was developed document THE INTEGRATED REGIONAL POLYCENTRIC DEVELOPMENT PLANS FOR THE WARSAW MODLIN AIRPORT CATCHMENT AREA. The plan developed takes into account the findings of the Mazovian voivodeship spatial development plan, specifying the details of its provisions where possible. The development is the first step for the implementation of the concept of the Modlin Airport City. The accomplishment of this ambitious vision will only be possible with hard work of a number of entities, as well as taking into account the former Modlin Fortress, currently under revitalisation, in concepts and plans.

  6. Evaluation of Charlottesville checkpoint operations

    DOT National Transportation Integrated Search

    1985-05-01

    Under a grant from the Virginia Office of Highway Safety, the Charlottesville Police Department implemented a Driver's License and Sobriety Checkpoint Program from December 30, 1983 to December 31, 1984. During the period, 94 checkpoint operations we...

  7. 14 CFR 221.52 - Airport to airport application, accessorial services.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Airport to airport application, accessorial... Charges § 221.52 Airport to airport application, accessorial services. Tariffs shall specify whether or not the fares therein include services in addition to airport-to-airport transportation. ...

  8. 14 CFR 221.52 - Airport to airport application, accessorial services.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Airport to airport application, accessorial... Charges § 221.52 Airport to airport application, accessorial services. Tariffs shall specify whether or not the fares therein include services in addition to airport-to-airport transportation. ...

  9. 14 CFR 221.52 - Airport to airport application, accessorial services.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Airport to airport application, accessorial... Charges § 221.52 Airport to airport application, accessorial services. Tariffs shall specify whether or not the fares therein include services in addition to airport-to-airport transportation. ...

  10. 14 CFR 221.52 - Airport to airport application, accessorial services.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Airport to airport application, accessorial... Charges § 221.52 Airport to airport application, accessorial services. Tariffs shall specify whether or not the fares therein include services in addition to airport-to-airport transportation. ...

  11. 14 CFR 221.52 - Airport to airport application, accessorial services.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Airport to airport application, accessorial... Charges § 221.52 Airport to airport application, accessorial services. Tariffs shall specify whether or not the fares therein include services in addition to airport-to-airport transportation. ...

  12. The Scalable Checkpoint/Restart Library

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moody, A.

    The Scalable Checkpoint/Restart (SCR) library provides an interface that codes may use to worite our and read in application-level checkpoints in a scalable fashion. In the current implementation, checkpoint files are cached in local storage (hard disk or RAM disk) on the compute nodes. This technique provides scalable aggregate bandwidth and uses storage resources that are fully dedicated to the job. This approach addresses the two common drawbacks of checkpointing a large-scale application to a shared parallel file system, namely, limited bandwidth and file system contention. In fact, on current platforms, SCR scales linearly with the number of compute nodes.more » It has been benchmarked as high as 720GB/s on 1094 nodes of Atlas, which is nearly two orders of magnitude faster thanthe parallel file system.« less

  13. 14 CFR 382.55 - May carriers impose security screening procedures for passengers with disabilities that go beyond...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Accessibility of Airport Facilities § 382.55 May carriers impose security screening procedures for passengers..., including those with disabilities, are subject to TSA security screening requirements at U.S. airports. In addition, passengers at foreign airports, including those with disabilities, may be subject to security...

  14. 14 CFR 382.55 - May carriers impose security screening procedures for passengers with disabilities that go beyond...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Accessibility of Airport Facilities § 382.55 May carriers impose security screening procedures for passengers..., including those with disabilities, are subject to TSA security screening requirements at U.S. airports. In addition, passengers at foreign airports, including those with disabilities, may be subject to security...

  15. 14 CFR 382.55 - May carriers impose security screening procedures for passengers with disabilities that go beyond...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Accessibility of Airport Facilities § 382.55 May carriers impose security screening procedures for passengers..., including those with disabilities, are subject to TSA security screening requirements at U.S. airports. In addition, passengers at foreign airports, including those with disabilities, may be subject to security...

  16. 14 CFR 382.53 - What information must carriers give individuals with a vision or hearing impairment at airports?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... foreign airport, to the extent that this does not interfere with employees' safety and security duties as... individuals with a vision or hearing impairment at airports? 382.53 Section 382.53 Aeronautics and Space... NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL Accessibility of Airport Facilities § 382.53 What...

  17. 14 CFR 382.53 - What information must carriers give individuals with a vision or hearing impairment at airports?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... foreign airport, to the extent that this does not interfere with employees' safety and security duties as... individuals with a vision or hearing impairment at airports? 382.53 Section 382.53 Aeronautics and Space... NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL Accessibility of Airport Facilities § 382.53 What...

  18. 14 CFR 382.53 - What information must carriers give individuals with a vision or hearing impairment at airports?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... foreign airport, to the extent that this does not interfere with employees' safety and security duties as... individuals with a vision or hearing impairment at airports? 382.53 Section 382.53 Aeronautics and Space... NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL Accessibility of Airport Facilities § 382.53 What...

  19. 33 CFR 162.20 - Flushing Bay near La Guardia Airport, Flushing, N.Y.; restricted area.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Airport, Flushing, N.Y.; restricted area. 162.20 Section 162.20 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.20 Flushing Bay near La Guardia Airport, Flushing, N.Y.; restricted area. (a...

  20. 33 CFR 162.20 - Flushing Bay near La Guardia Airport, Flushing, N.Y.; restricted area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Airport, Flushing, N.Y.; restricted area. 162.20 Section 162.20 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.20 Flushing Bay near La Guardia Airport, Flushing, N.Y.; restricted area. (a...

  1. Airport noise

    NASA Technical Reports Server (NTRS)

    Pendley, R. E.

    1982-01-01

    The problem of airport noise at several airports and air bases is detailed. Community reactions to the noise, steps taken to reduce jet engine noise, and the effect of airport use restrictions and curfews on air transportation are discussed. The adverse effect of changes in allowable operational noise on airport safety and altenative means for reducing noise pollution are considered. Community-airport relations and public relations are discussed.

  2. Emergency Preparedness for Catastrophic Events at Small and Medium Sized Airports: Lacking or Not?

    NASA Technical Reports Server (NTRS)

    Sweet, Kathleen M.

    2007-01-01

    The implementation of security methods and processes in general has had a decisive impact on the aviation industry. However, efforts to effectively coordinate varied aspects of security protocols between agencies and general aviation components have not been adequately addressed. Whether or not overall security issues, especially with regard to planning for catastrophic terrorist events, have been neglected at the nation's smaller airports is the main topic of this paper. For perspective, the term general aviation is generally accepted to include all flying except for military and scheduled airline operations. Genera aviation makes up more than 1 percent of the U.S. Gross Domestic Product and supports almost 1.3 mission high-skilled jobs in professional services and manufacturing and hence is an important component of the aviation industry (AOPA, n.d.). In both conceptual and practical terms, this paper argues for the proactive management of security planning and repeated security awareness training from both an individual and an organizational perspective within the general aviation venue. The results of a research project incorporating survey data from general aviation and small commercial airport managers as well as Transportation Security Administration (TSA) employees are reported. Survey findings suggest that miscommunication does take place on different organizational levels and that between TSA employees and airport management interaction can be contentious and cooperation diminished. The importance of organizational training for decreasing conflict and increasing security and preparedness is discussed as a primary implication.

  3. Semiannual Report to Congress on the Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1986-05-30

    and airport security measures in effect. Section V of this report provides a smry of firearms which were detected at screening points under suspicious...with the Secretary of State concerning threats, and (3) the inclusion of a sumnmary on foreign airport security in the Semiannual Report to Congress on...International Civil Aviation Organization (ICAO) to embark inediately upon an intensified program aimed at responding to the need for enhanced airport security . As

  4. A new look at NHTSA's evaluation of the 1984 Charlottesville Sobriety Checkpoint Program: implications for current checkpoint issues.

    PubMed

    Voas, Robert B

    2008-03-01

    Currently, the implementation of sobriety checkpoint programs, which have been demonstrated to be effective in reducing alcohol-related crashes, is limited by the belief that they require large consignments of police officers and result in few arrests. However, one of the earliest evaluations of a checkpoint program in Charlottesville, Virginia, demonstrated that effective checkpoints could be mounted in which police officers made as many arrests as officers on regular patrols. That study was printed by the NHTSA but was not published in a peer-reviewed journal. Because of its significance to current issues in the staffing of and procedures for checkpoint operations, this article reanalyzes the results of that study and describes the procedures implemented in checkpoints. A before-and-after control design was used to measure the change in nighttime crashes from three baseline years to the program year. Two analyses were conducted: the first on the percentage of all crashes occurring at night in the test city--Charlottesville--and the second on the percentage of all nighttime crashes in the state of Virginia that occurred in the test city. In addition, three waves of random-digit-dialing telephone surveys were conducted: one before and two during the checkpoint program in the test city, and the comparison city, Blacksburg. Finally, the number of impaired-driving arrests per officer hour at the checkpoints was compared with the number of arrests per hour by officers on regular patrol and the effect on arrests of the use of passive sensors was determined. The monthly percentage of nighttime crashes in Charlottesville was reduced by 17% (p = 000) in relation to the baseline level. The percentage of nighttime crashes in the state of Virginia that occurred in Charlottesville was reduced by 11% (p = .013) from baseline levels. Drivers arrested at checkpoints had lower BACs than those arrested by the regular patrols; however, the conviction rates were the same. The arrest

  5. Immune checkpoint therapy in liver cancer.

    PubMed

    Xu, Feng; Jin, Tianqiang; Zhu, Yuwen; Dai, Chaoliu

    2018-05-29

    Immune checkpoints include stimulatory and inhibitory checkpoint molecules. In recent years, inhibitory checkpoints, including cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), programmed cell death protein-1 (PD-1), and programmed cell death ligand 1 (PD-L1), have been identified to suppress anti-tumor immune responses in solid tumors. Novel drugs targeting immune checkpoints have succeeded in cancer treatment. Specific PD-1 blockades were approved for treatment of melanoma in 2014 and for treatment of non-small-cell lung cancer in 2015 in the United States, European Union, and Japan. Preclinical and clinical studies show immune checkpoint therapy provides survival benefit for greater numbers of patients with liver cancer, including hepatocellular carcinoma and cholangiocarcinoma, two main primary liver cancers. The combination of anti-PD-1/PD-L1 with anti-CTLA-4 antibodies is being evaluated in phase 1, 2 or 3 trials, and the results suggest that an anti-PD-1 antibody combined with locoregional therapy or other molecular targeted agents is an effective treatment strategy for HCC. In addition, studies on activating co-stimulatory receptors to enhance anti-tumor immune responses have increased our understanding regarding this immunotherapy in liver cancer. Epigenetic modulations of checkpoints for improving the tumor microenvironment also expand our knowledge of potential therapeutic targets in improving the tumor microenvironment and restoring immune recognition and immunogenicity. In this review, we summarize current knowledge and recent developments in immune checkpoint-based therapies for the treatment of hepatocellular carcinoma and cholangiocarcinoma and attempt to clarify the mechanisms underlying its effects.

  6. New MagViz Airport Liquid Analysis System Undergoes Testing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2008-12-18

    LOS ALAMOS, New Mexico, December 16, 2008—An innovative application of a technology first used for medical imaging may enhance airport security if Los Alamos National Laboratory scientists are successful. Los Alamos technologists have adapted Magnetic Res

  7. Airport and superficial femoral artery obstruction due to a wandering coronary stent: the possibility of airport detection of modern implant metals.

    PubMed

    Teijink, J A W; van Herwaarden, J A; van den Berg, J C; Overtoom, T C; Moll, F L

    2004-06-01

    In the treatment of coronary artery disease, peripheral loss of a coronary stent is an unusual complication. We present the case of a patient who suggested that his right leg claudication was caused by a slipped coronary stent 2 years previously. The patient was convinced about this unusual finding based on an airport security check. Examination proved him to be right. However, the ability to detect an object using eddy currents is dependent on the object's permeability and its conductivity. Ferrous (iron) content is not the critical factor. Modern implant materials and processing techniques result in implants that are difficult to magnetize i.e. their permeability is very low. In addition their conductivity is very low. This enables modern implants to escape detection at airports. For this reason the event at the airport, as described by our patient, is considered coincidental.

  8. Airport Capital Improvement Planning: Stewardship for Airport Development

    DOT National Transportation Integrated Search

    1997-09-01

    "Airport Capital Improvement Planning: Stewardship for Airport Development", was : originally written in October, 1995. It documented an effort to implement the : concept of capital improvement planning with the airport development industry. : Airpor...

  9. New MagViz Airport Liquid Analysis System Undergoes Testing

    ScienceCinema

    None

    2017-12-09

    LOS ALAMOS, New Mexico, December 16, 2008—An innovative application of a technology first used for medical imaging may enhance airport security if Los Alamos National Laboratory scientists are successful. Los Alamos technologists have adapted Magnetic Res

  10. Semiannual Report to Congress on the Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1985-11-07

    hijackings since 1973 during any comparable 6-month period. (See Exhibits 1, 2, and 3) Air carrier and airport security measures required by the FAA have...enforcement support for airline passenger boarding and airport security measures. The passengers, who are the principal beneficiaries of the security program

  11. Experimental evaluation of sobriety checkpoint programs

    DOT National Transportation Integrated Search

    1995-06-01

    Six California communities were selected to participate in the study on the basis of comparability and isolation from each other. Four of the communities' police departments implemented programs of sobriety checkpoints; the checkpoint configurations ...

  12. Multiple functions of the S-phase checkpoint mediator.

    PubMed

    Tanaka, Katsunori

    2010-01-01

    There is mounting evidence that replication defects are the major source of spontaneous genomic instability in cells, and that S-phase checkpoints are the principal defense against such instability. The S-phase checkpoint mediator protein Mrc1/Claspin mediates the checkpoint response to replication stress by facilitating phosphorylation of effector kinase by a sensor kinase. In this review, the multiple functions and the regulation of the S-phase checkpoint mediator are discussed.

  13. Securing General Aviation

    DTIC Science & Technology

    2009-03-03

    ajor vulnerabilities still exist in ... general aviation security ,”3 the commission did not further elaborate on the nature of those vulnerabilities...commercial operations may make them an attractive alternative to terrorists seeking to identify and exploit vulnerabilities in aviation security . In this...3, 2003, p. A7. 2 See Report of the Aviation Security Advisory Committee Working Group on General Aviation Airport Security (October 1, 2003); and

  14. Advances of Immune Checkpoint Inhibitors in Tumor Immunotherapy

    NASA Astrophysics Data System (ADS)

    Guo, Qiao

    2018-01-01

    Immune checkpoints are cell surface molecules that can fine-tune the immune responses, they are crucial for modulating the duration and amplitude of immune reactions while maintaining self-tolerance in order to minimize autoimmune responses. Numerous studies have demonstrated that tumors cells can directly express immune-checkpoint molecules, or induce many inhibitory molecules expression in the tumor microenvironment to inhibit the anti-tumor immunity. Releasing these brakes has emerged as an exciting strategy to cure cancer. In the past few years, clinical trials with therapeutic antibodies targeting to the checkpoint molecules CTLA-4 and PD-1 have rekindled the hope for cancer immunotherapy. In contrast to the conventional treatment, checkpoint inhibitors induce broad and durable antitumor responses. In the future, treatment may involve combination therapy to target different checkpoint molecules and stages of the adaptive immune responses. In this review, we summarized the recent advances of the study and development of other checkpoint molecules in tumor immunotherapy.

  15. 49 CFR 1562.29 - Armed security officer requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY OPERATIONS IN THE WASHINGTON, DC, METROPOLITAN AREA Ronald Reagan Washington National Airport: Enhanced Security Procedures for... 49 Transportation 9 2013-10-01 2013-10-01 false Armed security officer requirements. 1562.29...

  16. 49 CFR 1562.29 - Armed security officer requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY OPERATIONS IN THE WASHINGTON, DC, METROPOLITAN AREA Ronald Reagan Washington National Airport: Enhanced Security Procedures for... 49 Transportation 9 2014-10-01 2014-10-01 false Armed security officer requirements. 1562.29...

  17. 49 CFR 1562.29 - Armed security officer requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY OPERATIONS IN THE WASHINGTON, DC, METROPOLITAN AREA Ronald Reagan Washington National Airport: Enhanced Security Procedures for... 49 Transportation 9 2012-10-01 2012-10-01 false Armed security officer requirements. 1562.29...

  18. Efficient Checkpointing of Virtual Machines using Virtual Machine Introspection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aderholdt, Ferrol; Han, Fang; Scott, Stephen L

    Cloud Computing environments rely heavily on system-level virtualization. This is due to the inherent benefits of virtualization including fault tolerance through checkpoint/restart (C/R) mechanisms. Because clouds are the abstraction of large data centers and large data centers have a higher potential for failure, it is imperative that a C/R mechanism for such an environment provide minimal latency as well as a small checkpoint file size. Recently, there has been much research into C/R with respect to virtual machines (VM) providing excellent solutions to reduce either checkpoint latency or checkpoint file size. However, these approaches do not provide both. This papermore » presents a method of checkpointing VMs by utilizing virtual machine introspection (VMI). Through the usage of VMI, we are able to determine which pages of memory within the guest are used or free and are better able to reduce the amount of pages written to disk during a checkpoint. We have validated this work by using various benchmarks to measure the latency along with the checkpoint size. With respect to checkpoint file size, our approach results in file sizes within 24% or less of the actual used memory within the guest. Additionally, the checkpoint latency of our approach is up to 52% faster than KVM s default method.« less

  19. Semiannual Report to Congress on the Effectiveness of the Civil Aviation Security Program.

    DTIC Science & Technology

    1984-10-11

    deterred by airline and airport security procedures cannot be determined with certainty. However, the number of firearms detected at passenger screening... airport security measures continue to provide increased safety and protection to air travelers, aircraft crewmembers, air carrier aircraft, and air

  20. 49 CFR 1546.103 - Form, content, and availability of security program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... security program is acceptable only if TSA finds that the security program provides a level of protection similar to the level of protection provided by U.S. aircraft operators serving the same airports. Foreign... the same airport, if TSA determines that such procedures are necessary to provide a similar level of...

  1. A decision framework for managing risk to airports from terrorist attack.

    PubMed

    Shafieezadeh, Abdollah; Cha, Eun J; Ellingwood, Bruce R

    2015-02-01

    This article presents an asset-level security risk management framework to assist stakeholders of critical assets with allocating limited budgets for enhancing their safety and security against terrorist attack. The proposed framework models the security system of an asset, considers various threat scenarios, and models the sequential decision framework of attackers during the attack. Its novel contributions are the introduction of the notion of partial neutralization of attackers by defenders, estimation of total loss from successful, partially successful, and unsuccessful actions of attackers at various stages of an attack, and inclusion of the effects of these losses on the choices made by terrorists at various stages of the attack. The application of the proposed method is demonstrated in an example dealing with security risk management of a U.S. commercial airport, in which a set of plausible threat scenarios and risk mitigation options are considered. It is found that a combination of providing blast-resistant cargo containers and a video surveillance system on the airport perimeter fence is the best option based on minimum expected life-cycle cost considering a 10-year service period. © 2014 Society for Risk Analysis.

  2. Business Centre Development Model of Airport Area in Supporting Airport Sustainability in Indonesia

    NASA Astrophysics Data System (ADS)

    Setiawan, MI; Surjokusumo, S.; Ma'soem, DM; Johan, J.; Hasyim, C.; Kurniasih, N.; Sukoco, A.; Dhaniarti, I.; Suyono, J.; Sudapet, IN; Nasihien, RD; Mudjanarko, SW; Wulandari, A.; Ahmar, Ansari S.; Wajdi, MBN

    2018-01-01

    Airport is expected to play the role in enhancing the economic level of the region, especially the local people around the airport. The Aero City concept in developing an airport might also develop a city centreed in the airport that combining airport oriented business development, business actors and local people around the airport area. This study aims to generate development model of business centre at the airports in Indonesia. This is a mixed method based study. The population includes 296 airports under government management, government subsidiary and military. By using stratified random sampling, there were 151 sample airports. The results show that business centre development in the airport area will be related with the airport management and the commercial property (business centre) growth at the airport. Aero City in Indonesia can be developed by partnership system between government and private sector that consists of construction, development, and implementation of commercial property such as hotel, apartment, retail, office, etc. Based on the result of T-Value test, Airport Performance variable predicted to have significant influence on Gross Regional Domestic Product Central Business District performance.

  3. Checkpointing and Recovery in Distributed and Database Systems

    ERIC Educational Resources Information Center

    Wu, Jiang

    2011-01-01

    A transaction-consistent global checkpoint of a database records a state of the database which reflects the effect of only completed transactions and not the results of any partially executed transactions. This thesis establishes the necessary and sufficient conditions for a checkpoint of a data item (or the checkpoints of a set of data items) to…

  4. The Use of Sobriety Checkpoints for Impaired Driving Enforcement

    DOT National Transportation Integrated Search

    1990-11-01

    Sobriety checkpoints have been a valuable tool for law enforcement's continuing fight to remove impaired drivers from the road. The purpose of the checkpoint is twofold; to apprehend impaired drivers at the physical location of the checkpoint; and se...

  5. Wireless Channel Characterization in the Airport Surface Environment

    NASA Technical Reports Server (NTRS)

    Neville, Joshua T.

    2004-01-01

    Given the anticipated increase in air traffic in the coming years, modernization of the National Airspace System (NAS) is a necessity. Part of this modernization effort will include updating current communication, navigation, and surveillance (CNS) systems to deal with the increased traffic as well as developing advanced CNS technologies for the systems. An example of such technology is the integrated CNS (ICNS) network being developed by the Advanced CNS Architecture and Systems Technology (ACAST) group for use in the airport surface environment. The ICNS network would be used to convey voice/data between users in a secure and reliable manner. The current surface system only supports voice and does so through an obsolete physical infrastructure. The old system is vulnerable to outages and costly to maintain. The proposed ICNS network will include a wireless radio link. To ensure optimal performance, a thorough and accurate characterization of the channel across which the link would operate is necessary. The channel is the path the signal takes from the transmitter to the receiver and is prone to various forms of interference. Channel characterization involves a combination of analysis, simulation, and measurement. My work this summer was divided into four tasks. The first task required compiling and reviewing reference material that dealt with the characterization and modeling of aeronautical channels. The second task involved developing a systematic approach that could be used to group airports into classes, e.g. small airfields, medium airports, large open airports, large cluttered airports, etc. The third task consisted of implementing computer simulations of existing channel models. The fourth task entailed measuring possible interference sources in the airport surface environment via a spectrum analyzer.

  6. Affinity-aware checkpoint restart

    DOE PAGES

    Saini, Ajay; Rezaei, Arash; Mueller, Frank; ...

    2014-12-08

    Current checkpointing techniques employed to overcome faults for HPC applications result in inferior application performance after restart from a checkpoint for a number of applications. This is due to a lack of page and core affinity awareness of the checkpoint/restart (C/R) mechanism, i.e., application tasks originally pinned to cores may be restarted on different cores, and in case of non-uniform memory architectures (NUMA), quite common today, memory pages associated with tasks on a NUMA node may be associated with a different NUMA node after restart. Here, this work contributes a novel design technique for C/R mechanisms to preserve task-to-core mapsmore » and NUMA node specific page affinities across restarts. Experimental results with BLCR, a C/R mechanism, enhanced with affinity awareness demonstrate significant performance benefits of 37%-73% for the NAS Parallel Benchmark codes and 6-12% for NAMD with negligible overheads instead of up to nearly four times longer an execution times without affinity-aware restarts on 16 cores.« less

  7. Affinity-aware checkpoint restart

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saini, Ajay; Rezaei, Arash; Mueller, Frank

    Current checkpointing techniques employed to overcome faults for HPC applications result in inferior application performance after restart from a checkpoint for a number of applications. This is due to a lack of page and core affinity awareness of the checkpoint/restart (C/R) mechanism, i.e., application tasks originally pinned to cores may be restarted on different cores, and in case of non-uniform memory architectures (NUMA), quite common today, memory pages associated with tasks on a NUMA node may be associated with a different NUMA node after restart. Here, this work contributes a novel design technique for C/R mechanisms to preserve task-to-core mapsmore » and NUMA node specific page affinities across restarts. Experimental results with BLCR, a C/R mechanism, enhanced with affinity awareness demonstrate significant performance benefits of 37%-73% for the NAS Parallel Benchmark codes and 6-12% for NAMD with negligible overheads instead of up to nearly four times longer an execution times without affinity-aware restarts on 16 cores.« less

  8. Phosphorylation of Minichromosome Maintenance 3 (MCM3) by Checkpoint Kinase 1 (Chk1) Negatively Regulates DNA Replication and Checkpoint Activation.

    PubMed

    Han, Xiangzi; Mayca Pozo, Franklin; Wisotsky, Jacob N; Wang, Benlian; Jacobberger, James W; Zhang, Youwei

    2015-05-08

    Mechanisms controlling DNA replication and replication checkpoint are critical for the maintenance of genome stability and the prevention or treatment of human cancers. Checkpoint kinase 1 (Chk1) is a key effector protein kinase that regulates the DNA damage response and replication checkpoint. The heterohexameric minichromosome maintenance (MCM) complex is the core component of mammalian DNA helicase and has been implicated in replication checkpoint activation. Here we report that Chk1 phosphorylates the MCM3 subunit of the MCM complex at Ser-205 under normal growth conditions. Mutating the Ser-205 of MCM3 to Ala increased the length of DNA replication track and shortened the S phase duration, indicating that Ser-205 phosphorylation negatively controls normal DNA replication. Upon replicative stress treatment, the inhibitory phosphorylation of MCM3 at Ser-205 was reduced, and this reduction was accompanied with the generation of single strand DNA, the key platform for ataxia telangiectasia mutated and Rad3-related (ATR) activation. As a result, the replication checkpoint is activated. Together, these data provide significant insights into the regulation of both normal DNA replication and replication checkpoint activation through the novel phosphorylation of MCM3 by Chk1. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  9. Airport Security Act of 2013

    THOMAS, 113th Congress

    Rep. Johnson, Henry C. "Hank," Jr. [D-GA-4

    2013-11-14

    House - 01/09/2014 Referred to the Subcommittee on Crime, Terrorism, Homeland Security, and Investigations. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  10. Pseudoprogression and hyperprogression after checkpoint blockade.

    PubMed

    Wang, Qiaohong; Gao, Jingze; Wu, Xia

    2018-05-01

    Immune checkpoint inhibitors appear to be one of the most promising immunotherapies with significant clinical benefits and durable responses in multiple tumor types. A heterogeneity of responses appears in patients receiving checkpoint blockade, including pseudoprogression where the tumor burden or number of tumor lesions increases initially before decreasing. Another special response observed after checkpoint blockade is hyperprogression, a phenomenon reflecting a very rapid tumor progression following immunotherapy, suggesting that checkpoint blockade could impact detrimentally on a small subset of patients. As immunotherapeutics, especially anti-PD-1/PD-L1 agents, become more widely available, evaluating the efficacy of these novel drugs poses a major challenge to clinicians, who aim to avoid either premature withdrawal of the treatment or prolonging ineffective treatment. Although the mechanism and recognition of pseudoprogression have gradually come to light, the incidence, basis, identification and predictive biomarkers of hyperprogression have been largely unknown, and this review documents the existing research findings and points out the areas where further studies are badly needed. Copyright © 2018 Elsevier B.V. All rights reserved.

  11. Checkpoint triggering in a computer system

    DOEpatents

    Cher, Chen-Yong

    2016-09-06

    According to an aspect, a method for triggering creation of a checkpoint in a computer system includes executing a task in a processing node of the computer system and determining whether it is time to read a monitor associated with a metric of the task. The monitor is read to determine a value of the metric based on determining that it is time to read the monitor. A threshold for triggering creation of the checkpoint is determined based on the value of the metric. Based on determining that the value of the metric has crossed the threshold, the checkpoint including state data of the task is created to enable restarting execution of the task upon a restart operation.

  12. Hallmarks of response to immune checkpoint blockade

    PubMed Central

    Cogdill, Alexandria P; Andrews, Miles C; Wargo, Jennifer A

    2017-01-01

    Unprecedented advances have been made in the treatment of cancer through the use of immune checkpoint blockade, with approval of several checkpoint blockade regimens spanning multiple cancer types. However, responses to this form of therapy are not universal, and insights are clearly needed to identify optimal biomarkers of response and to combat mechanisms of therapeutic resistance. A working knowledge of the hallmarks of cancer yields insight into responses to immune checkpoint blockade, although the focus of this is rather tumour-centric and additional factors are pertinent, including host immunity and environmental influences. Herein, we describe the foundation for pillars and hallmarks of response to immune checkpoint blockade, with a discussion of their relevance to immune monitoring and mechanisms of resistance. Evolution of this understanding will ultimately help guide treatment strategies to enhance therapeutic responses. PMID:28524159

  13. Airport testing an explosives detection portal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rhykerd, C.; Linker, K.; Hannum, D.

    1998-08-01

    At the direction of the US Congress, following the Pan Am 103 and TWA 800 crashes, the Federal Aviation Administration funded development of non-invasive techniques to screen airline passengers for explosives. Such an explosives detection portal, developed at Sandia National Laboratories, was field tested at the Albuquerque International airport in September 1997. During the 2-week field trial, 2,400 passengers were screened and 500 surveyed. Throughput, reliability, maintenance and sensitivity were studied. Follow-up testing at Sandia and at Idaho National Engineering and Environmental Laboratory was conducted. A passenger stands in the portal for five seconds while overhead fans blow air overmore » his body. Any explosive vapors or dislodged particles are collected in vents at the feet. Explosives are removed from the air in a preconcentrator and subsequently directed into an ion mobility spectrometer for detection. Throughput measured 300 passengers per hour. The non-invasive portal can detect subfingerprint levels of explosives residue on clothing. A survey of 500 passengers showed a 97% approval rating, with 99% stating that such portals, if effective, should be installed in airports to improve security. Results of the airport test, as well as operational issues, are discussed.« less

  14. Immune checkpoint inhibitor-related myocarditis.

    PubMed

    Tajiri, Kazuko; Aonuma, Kazutaka; Sekine, Ikuo

    2018-01-01

    Immune checkpoint inhibitors have demonstrated significant clinical benefit in many cancers. The clinical benefit afforded by these treatments can be accompanied by a unique and distinct spectrum of adverse events. Recently, several fatal cases of immune checkpoint inhibitor-related myocarditis were reported. Although its frequency is comparatively lower than that of other immune-related adverse events, myocarditis can lead to circulatory collapse and lethal ventricular arrhythmia. Immune checkpoints, cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death protein 1 (PD-1), play important roles in establishing peripheral tolerance to the heart. Evidence from studies using genetically engineered mouse models suggests that CTLA-4 signaling terminates proliferation and promotes anergy during the primary response to cardiac self-peptide recognition. PD-1 signaling restrains autoreactive T cells that enter the peripheral tissues and recognize cardiac-peptide, maintaining them in an anergic state. Patients affected by immune checkpoint inhibitor-related myocarditis often experience rapid onset of profound hemodynamic compromise progressing to cardiogenic shock. Early diagnosis is mandatory to address specific therapy and correct the timing of circulatory support. However, the diagnosis of myocarditis is challenging due to the heterogeneity of clinical presentations. Owing to its early onset, nonspecific symptomatology and fulminant progression, especially when these drugs are used in combination, oncologists should be vigilant for immune checkpoint inhibitor-related myocarditis. With many questions yet to be answered, from basic immune biology to clinical management, future research should aim to optimize the use of these drugs by identifying predictive biomarkers of either a response to therapy or the risks of myocarditis development. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. 14 CFR 121.445 - Pilot in command airport qualification: Special areas and airports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Pilot in command airport qualification... Qualifications § 121.445 Pilot in command airport qualification: Special areas and airports. (a) The... any person serve, as pilot in command to or from an airport determined to require special airport...

  16. 14 CFR 121.445 - Pilot in command airport qualification: Special areas and airports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Pilot in command airport qualification... Qualifications § 121.445 Pilot in command airport qualification: Special areas and airports. (a) The... any person serve, as pilot in command to or from an airport determined to require special airport...

  17. 14 CFR 121.445 - Pilot in command airport qualification: Special areas and airports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Pilot in command airport qualification... Qualifications § 121.445 Pilot in command airport qualification: Special areas and airports. (a) The... any person serve, as pilot in command to or from an airport determined to require special airport...

  18. 14 CFR 121.445 - Pilot in command airport qualification: Special areas and airports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Pilot in command airport qualification... Qualifications § 121.445 Pilot in command airport qualification: Special areas and airports. (a) The... any person serve, as pilot in command to or from an airport determined to require special airport...

  19. 14 CFR 121.445 - Pilot in command airport qualification: Special areas and airports.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Pilot in command airport qualification... Qualifications § 121.445 Pilot in command airport qualification: Special areas and airports. (a) The... any person serve, as pilot in command to or from an airport determined to require special airport...

  20. Checkpoint independence of most DNA replication origins in fission yeast

    PubMed Central

    Mickle, Katie L; Ramanathan, Sunita; Rosebrock, Adam; Oliva, Anna; Chaudari, Amna; Yompakdee, Chulee; Scott, Donna; Leatherwood, Janet; Huberman, Joel A

    2007-01-01

    Background In budding yeast, the replication checkpoint slows progress through S phase by inhibiting replication origin firing. In mammals, the replication checkpoint inhibits both origin firing and replication fork movement. To find out which strategy is employed in the fission yeast, Schizosaccharomyces pombe, we used microarrays to investigate the use of origins by wild-type and checkpoint-mutant strains in the presence of hydroxyurea (HU), which limits the pool of deoxyribonucleoside triphosphates (dNTPs) and activates the replication checkpoint. The checkpoint-mutant cells carried deletions either of rad3 (which encodes the fission yeast homologue of ATR) or cds1 (which encodes the fission yeast homologue of Chk2). Results Our microarray results proved to be largely consistent with those independently obtained and recently published by three other laboratories. However, we were able to reconcile differences between the previous studies regarding the extent to which fission yeast replication origins are affected by the replication checkpoint. We found (consistent with the three previous studies after appropriate interpretation) that, in surprising contrast to budding yeast, most fission yeast origins, including both early- and late-firing origins, are not significantly affected by checkpoint mutations during replication in the presence of HU. A few origins (~3%) behaved like those in budding yeast: they replicated earlier in the checkpoint mutants than in wild type. These were located primarily in the heterochromatic subtelomeric regions of chromosomes 1 and 2. Indeed, the subtelomeric regions defined by the strongest checkpoint restraint correspond precisely to previously mapped subtelomeric heterochromatin. This observation implies that subtelomeric heterochromatin in fission yeast differs from heterochromatin at centromeres, in the mating type region, and in ribosomal DNA, since these regions replicated at least as efficiently in wild-type cells as in

  1. Volcanic hazards to airports

    USGS Publications Warehouse

    Guffanti, M.; Mayberry, G.C.; Casadevall, T.J.; Wunderman, R.

    2009-01-01

    Volcanic activity has caused significant hazards to numerous airports worldwide, with local to far-ranging effects on travelers and commerce. Analysis of a new compilation of incidents of airports impacted by volcanic activity from 1944 through 2006 reveals that, at a minimum, 101 airports in 28 countries were affected on 171 occasions by eruptions at 46 volcanoes. Since 1980, five airports per year on average have been affected by volcanic activity, which indicates that volcanic hazards to airports are not rare on a worldwide basis. The main hazard to airports is ashfall, with accumulations of only a few millimeters sufficient to force temporary closures of some airports. A substantial portion of incidents has been caused by ash in airspace in the vicinity of airports, without accumulation of ash on the ground. On a few occasions, airports have been impacted by hazards other than ash (pyroclastic flow, lava flow, gas emission, and phreatic explosion). Several airports have been affected repeatedly by volcanic hazards. Four airports have been affected the most often and likely will continue to be among the most vulnerable owing to continued nearby volcanic activity: Fontanarossa International Airport in Catania, Italy; Ted Stevens Anchorage International Airport in Alaska, USA; Mariscal Sucre International Airport in Quito, Ecuador; and Tokua Airport in Kokopo, Papua New Guinea. The USA has the most airports affected by volcanic activity (17) on the most occasions (33) and hosts the second highest number of volcanoes that have caused the disruptions (5, after Indonesia with 7). One-fifth of the affected airports are within 30 km of the source volcanoes, approximately half are located within 150 km of the source volcanoes, and about three-quarters are within 300 km; nearly one-fifth are located more than 500 km away from the source volcanoes. The volcanoes that have caused the most impacts are Soufriere Hills on the island of Montserrat in the British West Indies

  2. Enhancing Immune Checkpoint Inhibitor Therapy In Kidney Cancer

    DTIC Science & Technology

    2016-10-01

    AWARD NUMBER: W81XWH-15-1-0141 TITLE: Enhancing Immune Checkpoint Inhibitor therapy in Kidney Cancer PRINCIPAL INVESTIGATOR: Hans-Joerg Hammers...Immune Checkpoint Inhibitor therapy in Kidney Cancer 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH- 15-1-0141 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...to develop strategies to enhance immune checkpoint inhibition in kidney cancer. The work is designed to test different strategies to induce or

  3. Enhancing Immune Checkpoint Inhibitor Therapy in Kidney Cancer

    DTIC Science & Technology

    2017-10-01

    AWARD NUMBER: W81XWH-15-1-0141 TITLE: Enhancing Immune Checkpoint Inhibitor therapy in Kidney Cancer PRINCIPAL INVESTIGATOR: Hans-Joerg Hammers...SUBTITLE Enhancing Immune Checkpoint Inhibitor therapy in Kidney Cancer 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH- 15-1-0141 5c. PROGRAM ELEMENT NUMBER...immune checkpoint inhibition in kidney cancer . The work is designed to test different strategies to induce or enhance the abscopal in a kidney cancer

  4. Immune checkpoint inhibitors: basics and challenges.

    PubMed

    Li, Bin; Chan, Ho Lam; Chen, Pingping

    2017-08-04

    Cancer is one of the most deadly diseases in modern world. The last decade has witnessed dramatic advances in the cancer treatment through immunotherapy. One extremely promising means to achieve anti-caner immunity is to block the immune checkpoint pathways, which mechanism was adopted by cancer cells to disguise themselves as regular components of human body. While checkpoint blockade is universally effective against a broad spectrum of cancer types and mostly unrestricted by certain gene mutation status, only a minority of patients achieved a complete response to such treatment. In this review we summarize the basic principles of immune checkpoint inhibitors and discuss potential mechanisms of resistance. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  5. The checkpoint ordering problem

    PubMed Central

    Hungerländer, P.

    2017-01-01

    Abstract We suggest a new variant of a row layout problem: Find an ordering of n departments with given lengths such that the total weighted sum of their distances to a given checkpoint is minimized. The Checkpoint Ordering Problem (COP) is both of theoretical and practical interest. It has several applications and is conceptually related to some well-studied combinatorial optimization problems, namely the Single-Row Facility Layout Problem, the Linear Ordering Problem and a variant of parallel machine scheduling. In this paper we study the complexity of the (COP) and its special cases. The general version of the (COP) with an arbitrary but fixed number of checkpoints is NP-hard in the weak sense. We propose both a dynamic programming algorithm and an integer linear programming approach for the (COP) . Our computational experiments indicate that the (COP) is hard to solve in practice. While the run time of the dynamic programming algorithm strongly depends on the length of the departments, the integer linear programming approach is able to solve instances with up to 25 departments to optimality. PMID:29170574

  6. Airport financing : smaller airports face future funding shortfalls

    DOT National Transportation Integrated Search

    1999-02-22

    Testimony before Subcommittee on Aviation, Committee on Transportation and : Infrastructure, House of Represenatives on airport funding issues. Testimony : focused on 1) how much funding has been made available to small airports for : capital develop...

  7. Template based parallel checkpointing in a massively parallel computer system

    DOEpatents

    Archer, Charles Jens [Rochester, MN; Inglett, Todd Alan [Rochester, MN

    2009-01-13

    A method and apparatus for a template based parallel checkpoint save for a massively parallel super computer system using a parallel variation of the rsync protocol, and network broadcast. In preferred embodiments, the checkpoint data for each node is compared to a template checkpoint file that resides in the storage and that was previously produced. Embodiments herein greatly decrease the amount of data that must be transmitted and stored for faster checkpointing and increased efficiency of the computer system. Embodiments are directed to a parallel computer system with nodes arranged in a cluster with a high speed interconnect that can perform broadcast communication. The checkpoint contains a set of actual small data blocks with their corresponding checksums from all nodes in the system. The data blocks may be compressed using conventional non-lossy data compression algorithms to further reduce the overall checkpoint size.

  8. 49 CFR 1546.213 - Access to cargo: Security threat assessments for cargo personnel in the United States.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... the cargo enters an airport Security Identification Display Area or is transferred to another TSA... under §§ 1546.101(a) or (b) accepts the cargo, until the cargo— (A) Enters an airport Security... 49 Transportation 9 2012-10-01 2012-10-01 false Access to cargo: Security threat assessments for...

  9. 49 CFR 1546.213 - Access to cargo: Security threat assessments for cargo personnel in the United States.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the cargo enters an airport Security Identification Display Area or is transferred to another TSA... under §§ 1546.101(a) or (b) accepts the cargo, until the cargo— (A) Enters an airport Security... 49 Transportation 9 2014-10-01 2014-10-01 false Access to cargo: Security threat assessments for...

  10. 49 CFR 1546.213 - Access to cargo: Security threat assessments for cargo personnel in the United States.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the cargo enters an airport Security Identification Display Area or is transferred to another TSA... under §§ 1546.101(a) or (b) accepts the cargo, until the cargo— (A) Enters an airport Security... 49 Transportation 9 2013-10-01 2013-10-01 false Access to cargo: Security threat assessments for...

  11. 49 CFR 1546.213 - Access to cargo: Security threat assessments for cargo personnel in the United States.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the cargo enters an airport Security Identification Display Area or is transferred to another TSA... under §§ 1546.101(a) or (b) accepts the cargo, until the cargo— (A) Enters an airport Security... 49 Transportation 9 2011-10-01 2011-10-01 false Access to cargo: Security threat assessments for...

  12. Prosthetic metal implants and airport metal detectors.

    PubMed

    Ismail, A; Dancey, A; Titley, O G

    2013-04-01

    Metal detectors have been present in airports and points of departure for some time. With the introduction of heightened security measures in response to fears of an increased threat of terrorism, they may become more prevalent in other public locations. The aim of this study was to ascertain which prosthetic devices activated metal detector devices used for security purposes. A range of prosthetic devices used commonly in orthopaedic and plastic surgery procedures were passed through an arch metal detector at Birmingham Airport in the UK. Additionally, each item was passed under a wand detector. Items tested included expandable breast prostheses, plates used in wrist and hand surgery, screws, K-wires, Autosuture™ ligation clips and staples. No prostheses were detected by the arch detector. The expandable implants and wrist plates were the only devices detected by passing the wand directly over them. No device was detected by the wand when it was under cover of the axillary soft tissue. Screws, K-wires, Autosuture™ clips and staples were not detected under any of the study conditions. Although unlikely to trigger a detector, it is possible that an expandable breast prosthesis or larger plate may do so. It is therefore best to warn patients of this so they can anticipate detection and further examination.

  13. Airport Capital Improvement Plan : stewardship for airport development

    DOT National Transportation Integrated Search

    1997-09-01

    This document summarizes efforts of the Federal Aviation Administration (FAA) Office : of the Associate Administrator for Airports to implement the concept of Airport Capital : Improvement Planning (ACIP). It is based on the experiences of the FAA's ...

  14. McrEngine: A Scalable Checkpointing System Using Data-Aware Aggregation and Compression

    DOE PAGES

    Islam, Tanzima Zerin; Mohror, Kathryn; Bagchi, Saurabh; ...

    2013-01-01

    High performance computing (HPC) systems use checkpoint-restart to tolerate failures. Typically, applications store their states in checkpoints on a parallel file system (PFS). As applications scale up, checkpoint-restart incurs high overheads due to contention for PFS resources. The high overheads force large-scale applications to reduce checkpoint frequency, which means more compute time is lost in the event of failure. We alleviate this problem through a scalable checkpoint-restart system, mcrEngine. McrEngine aggregates checkpoints from multiple application processes with knowledge of the data semantics available through widely-used I/O libraries, e.g., HDF5 and netCDF, and compresses them. Our novel scheme improves compressibility ofmore » checkpoints up to 115% over simple concatenation and compression. Our evaluation with large-scale application checkpoints show that mcrEngine reduces checkpointing overhead by up to 87% and restart overhead by up to 62% over a baseline with no aggregation or compression.« less

  15. 49 CFR 1544.228 - Access to cargo and cargo screening: Security threat assessments for cargo personnel in the...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... cargo enters an airport Security Identification Display Area or is transferred to another TSA-regulated... program accepts the cargo until the cargo— (A) Enters an airport Security Identification Display Area; (B... 49 Transportation 9 2012-10-01 2012-10-01 false Access to cargo and cargo screening: Security...

  16. 49 CFR 1544.228 - Access to cargo and cargo screening: Security threat assessments for cargo personnel in the...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... cargo enters an airport Security Identification Display Area or is transferred to another TSA-regulated... program accepts the cargo until the cargo— (A) Enters an airport Security Identification Display Area; (B... 49 Transportation 9 2014-10-01 2014-10-01 false Access to cargo and cargo screening: Security...

  17. 49 CFR 1544.228 - Access to cargo and cargo screening: Security threat assessments for cargo personnel in the...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... cargo enters an airport Security Identification Display Area or is transferred to another TSA-regulated... program accepts the cargo until the cargo— (A) Enters an airport Security Identification Display Area; (B... 49 Transportation 9 2013-10-01 2013-10-01 false Access to cargo and cargo screening: Security...

  18. 49 CFR 1544.228 - Access to cargo and cargo screening: Security threat assessments for cargo personnel in the...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... cargo enters an airport Security Identification Display Area or is transferred to another TSA-regulated... program accepts the cargo until the cargo— (A) Enters an airport Security Identification Display Area; (B... 49 Transportation 9 2011-10-01 2011-10-01 false Access to cargo and cargo screening: Security...

  19. Benchmark Airport Charges

    NASA Technical Reports Server (NTRS)

    deWit, A.; Cohn, N.

    1999-01-01

    The Netherlands Directorate General of Civil Aviation (DGCA) commissioned Hague Consulting Group (HCG) to complete a benchmark study of airport charges at twenty eight airports in Europe and around the world, based on 1996 charges. This study followed previous DGCA research on the topic but included more airports in much more detail. The main purpose of this new benchmark study was to provide insight into the levels and types of airport charges worldwide and into recent changes in airport charge policy and structure, This paper describes the 1996 analysis. It is intended that this work be repeated every year in order to follow developing trends and provide the most up-to-date information possible.

  20. Benchmark Airport Charges

    NASA Technical Reports Server (NTRS)

    de Wit, A.; Cohn, N.

    1999-01-01

    The Netherlands Directorate General of Civil Aviation (DGCA) commissioned Hague Consulting Group (HCG) to complete a benchmark study of airport charges at twenty eight airports in Europe and around the world, based on 1996 charges. This study followed previous DGCA research on the topic but included more airports in much more detail. The main purpose of this new benchmark study was to provide insight into the levels and types of airport charges worldwide and into recent changes in airport charge policy and structure. This paper describes the 1996 analysis. It is intended that this work be repeated every year in order to follow developing trends and provide the most up-to-date information possible.

  1. Sobriety checkpoints reduce crash deaths on Tennessee roads

    DOT National Transportation Integrated Search

    1999-06-19

    Sobriety checkpoints are known to be effective in getting alcohol-impaired drivers off the roads. The National Highway Traffic Safety Administration funded equipment and conducted an evaluation of Tennessee's two-year statewide checkpoint demonstrati...

  2. Airport metal detector activation is rare after posterior spinal fusion in children with scoliosis.

    PubMed

    Fabricant, Peter D; Robles, Alex; Blanco, John S

    2013-12-01

    Since the September 11, 2001 terrorist attacks on the World Trade Center in New York City, travel security has become an ever-increasing priority in the United States. Frequent parent and patient inquiry and recent literature reports have generated interest in the impact of heightened security measures on patients with orthopaedic implants, and have indicated increasing rates of metal detector triggering. There are no reports to date, however, evaluating children and adolescents who have undergone posterior spinal fusion for scoliosis, so responses to patient and parent inquiries are not data-driven. The purpose of this study is to determine the frequency of airport metal detector triggering by patients who have had posterior-only spinal fusion and to characterise any potential predictors of metal detector activation. A cross-sectional study was performed by interviewing 90 patients who underwent posterior-only spinal fusion for a diagnosis of juvenile or adolescent idiopathic scoliosis and have travelled by air in the past year. Demographic, clinical and surgical instrumentation data were collected and evaluated, along with patients' reports of airport metal detector triggering and subsequent screening procedures. Five patients with stainless steel instrumentation (5.6 % of the cohort) triggered an airport walkthrough metal detector, and an additional five patients who did not trigger an airport detector triggered a handheld detector at a different venue. All patients who triggered an airport metal detector had stainless steel instrumentation implanted prior to 2008, and no patient with titanium instrumentation triggered any detector in any venue. All trigger events required subsequent screening procedures, even when an implant card was presented. In this cohort of children and adolescents with posterior spinal instrumentation, airport walkthrough metal detector triggering was a rare event. Therefore, we advise patients and families with planned posterior

  3. Mammalian Homologs of Yeast Checkpoint Genes

    DTIC Science & Technology

    2002-07-01

    pathway is sensitive to various forms of DNA damage Developmental Biology throughout the cell cycle . The DNA replication check- Yale University point...components would be ordered into pathways for mammalian checkpoint function, with emphasis on p53 regulation, cell cycle regulation, and complementation...structurally related to the human tumor suppressor ATM. MEC1 and RAD53, two essential genes, play a central role in DNA damage checkpoints at all cell cycle

  4. Co-inhibitory immune checkpoints in head and neck squamous cell carcinoma.

    PubMed

    Deng, W-W; Wu, L; Sun, Z-J

    2018-03-01

    The upregulation of co-inhibitory immune checkpoints hampers the immune response toward tumor cells and facilitates the tumor cells ability to evade immunosurveillance. Specific inhibitory immune checkpoint delivers inhibitory signals to T cells using multiple mechanisms. More in-depth understanding of the co-inhibitory immune checkpoints could be exploited for head and neck squamous cell carcinoma (HNSCC) treatment. In this review, we summarize the expression and the mechanism of partial co-inhibitory immune checkpoint signals and discuss targeting co-inhibitory immune checkpoints as an immunotherapeutic target for cancer therapy. This review may provide a better understanding of the co-inhibitory immune checkpoints and could promote applications of immunotherapy. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved.

  5. Viral-induced Modulation of Multiple Checkpoint Proteins in Cancers.

    PubMed

    Nuovo, Gerard J; Folcik, Virginia A; Magro, Cynthia

    2017-07-01

    Therapy with checkpoint inhibitors represents a major advance in cancer treatment. The purpose of this study was to examine the expression patterns of the checkpoint proteins programmed death ligand 1 (PD L1), PD L2, indoleamine 2,3-dioxygenase 1 (IDO1), and cytotoxic T-lymphocyte antigen 4 (CTLA4) in cancers including those associated with viral infections. Normal, noninflamed tissues rarely express checkpoint proteins with exceptions including the placenta and stomach. Expression of PD L1 was noted in 30%, PD L2 in 18%, IDO1 in 13%, and CTLA4 in 14% of 333 nonviral malignancies including endometrial, ovarian, lung, and breast cancers. The expression of each checkpoint protein was significantly higher among 166 cases of viral-related (mostly human papillomavirus) cancers where expression of PD L1 was noted in 84%, PD L2 in 67%, IDO1 in 61%, and CTLA4 in 37% (each P value <0.001); 97% of the viral-related cancers showed expression of at least 1 checkpoint protein. In addition, over 90% of the CD8 cells in the viral-associated cancers were quiescent based on low coexpression of Ki-67 as well as pSTAT1. It is concluded that viral infection in cancers is associated with the increased expression of key checkpoint proteins. This indicates that cancers with productive viral infection may be better targets for checkpoint inhibitor therapy.

  6. Determining the Effectiveness of Flexible Checkpoints : Traffic Tech

    DOT National Transportation Integrated Search

    2017-05-01

    Checkpoint operations are highly visible and are often used for Driving While Intoxicated (DWI) countermeasure enforcement efforts. However, checkpoints can be resource-intensive, so it is often difficult to generate as much use of that tactic as is ...

  7. Berkeley lab checkpoint/restart (BLCR) for Linux clusters

    DOE PAGES

    Hargrove, Paul H.; Duell, Jason C.

    2006-09-01

    This article describes the motivation, design and implementation of Berkeley Lab Checkpoint/Restart (BLCR), a system-level checkpoint/restart implementation for Linux clusters that targets the space of typical High Performance Computing applications, including MPI. Application-level solutions, including both checkpointing and fault-tolerant algorithms, are recognized as more time and space efficient than system-level checkpoints, which cannot make use of any application-specific knowledge. However, system-level checkpointing allows for preemption, making it suitable for responding to fault precursors (for instance, elevated error rates from ECC memory or network CRCs, or elevated temperature from sensors). Preemption can also increase the efficiency of batch scheduling; for instancemore » reducing idle cycles (by allowing for shutdown without any queue draining period or reallocation of resources to eliminate idle nodes when better fitting jobs are queued), and reducing the average queued time (by limiting large jobs to running during off-peak hours, without the need to limit the length of such jobs). Each of these potential uses makes BLCR a valuable tool for efficient resource management in Linux clusters. © 2006 IOP Publishing Ltd.« less

  8. "Isogaba Maware": quality control of genome DNA by checkpoints.

    PubMed

    Kitazono, A; Matsumoto, T

    1998-05-01

    Checkpoints maintain the interdependency of cell cycle events by permitting the onset of an event only after the completion of the preceding event. The DNA replication checkpoint induces a cell cycle arrest until the completion of the DNA replication. Similarly, the DNA damage checkpoint arrests cell cycle progression if DNA repair is incomplete. A number of genes that play a role in the two checkpoints have been identified through genetic studies in yeasts, and their homologues have been found in fly, mouse, and human. They form signaling cascades activated by a DNA replication block or DNA damage and subsequently generate the negative constraints on cell cycle regulators. The failure of these signaling cascades results in producing offspring that carry mutations or that lack a portion of the genome. In humans, defects in the checkpoints are often associated with cancer-prone diseases. Focusing mainly on the studies in budding and fission yeasts, we summarize the recent progress.

  9. Whiffing the Airport Interview

    ERIC Educational Resources Information Center

    Williamson, David

    2008-01-01

    An airport interview is an initial interview for a senior administrative position conducted at an airport hotel not too far from the campus in question. Meeting at an airport enables a search committee to interview a large number of candidates in a short period of time with a degree of confidentiality. At the conclusion of the airport interviews,…

  10. 77 FR 16552 - Extension of Agency Information Collection Activity Under OMB Review: Maryland-Three Airports...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-21

    ... coordinators in one of these airports, to submit personal information and fingerprints. TSA will use the applicant's information and fingerprints to conduct a security threat assessment. An applicant will not...

  11. Intellectual property issues of immune checkpoint inhibitors

    PubMed Central

    Storz, Ulrich

    2016-01-01

    Immune checkpoint inhibitors are drugs that interfere with tumor escape responses. Some members of this class are already approved, and expected to be blockbusters in the future. Many companies have developed patent activities in this field. This article focuses on the patent landscape, and discusses key players and cases related to immune checkpoint inhibitors. PMID:26466763

  12. The deterrent capability of sobriety checkpoints : summary of the American literature

    DOT National Transportation Integrated Search

    1992-03-01

    This report reviews and evaluates the scientific literature on sobriety checkpoints in the United States. Concerns about the constitutionality of checkpoint procedures initially limited the number of checkpoint programs in this country as well as con...

  13. The DNA Replication Checkpoint Directly Regulates MBF-Dependent G1/S Transcription▿

    PubMed Central

    Dutta, Chaitali; Patel, Prasanta K.; Rosebrock, Adam; Oliva, Anna; Leatherwood, Janet; Rhind, Nicholas

    2008-01-01

    The DNA replication checkpoint transcriptionally upregulates genes that allow cells to adapt to and survive replication stress. Our results show that, in the fission yeast Schizosaccharomyces pombe, the replication checkpoint regulates the entire G1/S transcriptional program by directly regulating MBF, the G1/S transcription factor. Instead of initiating a checkpoint-specific transcriptional program, the replication checkpoint targets MBF to maintain the normal G1/S transcriptional program during replication stress. We propose a mechanism for this regulation, based on in vitro phosphorylation of the Cdc10 subunit of MBF by the Cds1 replication-checkpoint kinase. Replacement of two potential phosphorylation sites with phosphomimetic amino acids suffices to promote the checkpoint transcriptional program, suggesting that Cds1 phosphorylation directly regulates MBF-dependent transcription. The conservation of MBF between fission and budding yeast, and recent results implicating MBF as a target of the budding yeast replication checkpoint, suggests that checkpoint regulation of the MBF transcription factor is a conserved strategy for coping with replication stress. Furthermore, the structural and regulatory similarity between MBF and E2F, the metazoan G1/S transcription factor, suggests that this checkpoint mechanism may be broadly conserved among eukaryotes. PMID:18662996

  14. 77 FR 4394 - Release of Airport Property: Orlando Executive Airport, Orlando, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-27

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Release of Airport Property: Orlando Executive Airport, Orlando, FL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Request for... 12.4 acres at the Orlando Executive Airport, Orlando, FL from the conditions, release certain...

  15. Strategy to Enhance International Supply Chain Security

    DTIC Science & Technology

    2007-07-01

    airports as part of the effort to secure air passenger travel . The security assessment crew traveling by air, land or sea cannot be considered only a... travel security issue. The assessment of a container ship’s crew or of a driver moving a truck into the secure area of a port are also supply chain...threats through its traveler screening and worker credentialing programs. The strategy to secure the supply chain reflects the larger security

  16. Immune checkpoint failures in inflammatory myopathies: An overview.

    PubMed

    Herbelet, Sandrine; De Bleecker, Jan L

    2018-06-06

    Dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM), immune mediated necrotizing myopathy (IMNM) and overlap myositis (OM) are classified as inflammatory myopathies (IM) with involvement of autoimmune features such as autoreactive lymphocytes and autoantibodies. Autoimmunity can be defined as a loss in self-tolerance and attack of autoantigens by the immune system. Self-tolerance is achieved by a group of immune mechanisms occurring in central and periphal lymphoid organs and tissues, called immune checkpoints, that work in synergy to protect the body from harmful immune reactions. Autoimmune disorders appear when immune checkpoints fail. In this review, the different immune checkpoint failures are discussed in DM, PM, IBM and IMNM. Exploring research contribution in each of these immune checkpoints might help to highlight research perspectives in the field and obtain a more complete picture of IM disease pathology. Copyright © 2018 Elsevier B.V. All rights reserved.

  17. Prosthetic metal implants and airport metal detectors

    PubMed Central

    Dancey, A; Titley, OG

    2013-01-01

    Introduction Metal detectors have been present in airports and points of departure for some time. With the introduction of heightened security measures in response to fears of an increased threat of terrorism, they may become more prevalent in other public locations. The aim of this study was to ascertain which prosthetic devices activated metal detector devices used for security purposes. Methods A range of prosthetic devices used commonly in orthopaedic and plastic surgery procedures were passed through an arch metal detector at Birmingham Airport in the UK. Additionally, each item was passed under a wand detector. Items tested included expandable breast prostheses, plates used in wrist and hand surgery, screws, K-wires, Autosuture™ ligation clips and staples. Results No prostheses were detected by the arch detector. The expandable implants and wrist plates were the only devices detected by passing the wand directly over them. No device was detected by the wand when it was under cover of the axillary soft tissue. Screws, K-wires, Autosuture™ clips and staples were not detected under any of the study conditions. Conclusions Although unlikely to trigger a detector, it is possible that an expandable breast prosthesis or larger plate may do so. It is therefore best to warn patients of this so they can anticipate detection and further examination. PMID:23827294

  18. Immune mediated neuropathy following checkpoint immunotherapy.

    PubMed

    Gu, Yufan; Menzies, Alexander M; Long, Georgina V; Fernando, S L; Herkes, G

    2017-11-01

    Checkpoint immunotherapy has revolutionised cancer therapy and is now standard treatment for many malignancies including metastatic melanoma. Acute inflammatory neuropathies, often labelled as Guillain-Barre syndrome, are an uncommon but potentially severe complication of checkpoint immunotherapy with individual cases described but never characterised as a group. We describe a case of acute sensorimotor and autonomic neuropathy following a single dose of combination ipilimumab and nivolumab for metastatic melanoma. A literature search was performed, identifying 14 other cases of acute neuropathy following checkpoint immunotherapy, with the clinical, electrophysiological and laboratory features summarised. Most cases described an acute sensorimotor neuropathy (92%) with hyporeflexia (92%) that could occur from induction up till many weeks after the final dose of therapy. In contrast to Guillain-Barre syndrome, the cerebrospinal fluid (CSF) analysis often shows a lymphocytic picture (50%) and the electrophysiology showed an axonal pattern (55%). Treatment was variable and often in combination. 11 cases received steroid therapy with only 1 death within this group, whereas of the 4 patients who did not receive steroid therapy there were 3 deaths. In conclusion checkpoint immunotherapy - induced acute neuropathies are distinct from and progress differently to Guillain-Barre syndrome. As with other immunotherapy related adverse events corticosteroid therapy should be initiated in addition to usual therapy. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Synaptonemal Complex Components Are Required for Meiotic Checkpoint Function in Caenorhabditis elegans

    PubMed Central

    Bohr, Tisha; Ashley, Guinevere; Eggleston, Evan; Firestone, Kyra; Bhalla, Needhi

    2016-01-01

    Synapsis involves the assembly of a proteinaceous structure, the synaptonemal complex (SC), between paired homologous chromosomes, and is essential for proper meiotic chromosome segregation. In Caenorhabditis elegans, the synapsis checkpoint selectively removes nuclei with unsynapsed chromosomes by inducing apoptosis. This checkpoint depends on pairing centers (PCs), cis-acting sites that promote pairing and synapsis. We have hypothesized that the stability of homolog pairing at PCs is monitored by this checkpoint. Here, we report that SC components SYP-3, HTP-3, HIM-3, and HTP-1 are required for a functional synapsis checkpoint. Mutation of these components does not abolish PC function, demonstrating they are bona fide checkpoint components. Further, we identify mutant backgrounds in which the instability of homolog pairing at PCs does not correlate with the synapsis checkpoint response. Altogether, these data suggest that, in addition to homolog pairing, SC assembly may be monitored by the synapsis checkpoint. PMID:27605049

  20. Cell cycle control, checkpoint mechanisms, and genotoxic stress.

    PubMed Central

    Shackelford, R E; Kaufmann, W K; Paules, R S

    1999-01-01

    The ability of cells to maintain genomic integrity is vital for cell survival and proliferation. Lack of fidelity in DNA replication and maintenance can result in deleterious mutations leading to cell death or, in multicellular organisms, cancer. The purpose of this review is to discuss the known signal transduction pathways that regulate cell cycle progression and the mechanisms cells employ to insure DNA stability in the face of genotoxic stress. In particular, we focus on mammalian cell cycle checkpoint functions, their role in maintaining DNA stability during the cell cycle following exposure to genotoxic agents, and the gene products that act in checkpoint function signal transduction cascades. Key transitions in the cell cycle are regulated by the activities of various protein kinase complexes composed of cyclin and cyclin-dependent kinase (Cdk) molecules. Surveillance control mechanisms that check to ensure proper completion of early events and cellular integrity before initiation of subsequent events in cell cycle progression are referred to as cell cycle checkpoints and can generate a transient delay that provides the cell more time to repair damage before progressing to the next phase of the cycle. A variety of cellular responses are elicited that function in checkpoint signaling to inhibit cyclin/Cdk activities. These responses include the p53-dependent and p53-independent induction of Cdk inhibitors and the p53-independent inhibitory phosphorylation of Cdk molecules themselves. Eliciting proper G1, S, and G2 checkpoint responses to double-strand DNA breaks requires the function of the Ataxia telangiectasia mutated gene product. Several human heritable cancer-prone syndromes known to alter DNA stability have been found to have defects in checkpoint surveillance pathways. Exposures to several common sources of genotoxic stress, including oxidative stress, ionizing radiation, UV radiation, and the genotoxic compound benzo[a]pyrene, elicit cell cycle

  1. Airport Remote Tower Sensor Systems

    NASA Technical Reports Server (NTRS)

    Papasin, Richard; Gawdiak, Yuri; Maluf, David A.; Leidich, Christopher; Tran, Peter B.

    2001-01-01

    Remote Tower Sensor Systems (RTSS) are proof-of-concept prototypes being developed by NASA/Ames Research Center (NASA/ARC) with collaboration with the FAA (Federal Aviation Administration) and NOAA (National Oceanic Atmospheric Administration). RTSS began with the deployment of an Airport Approach Zone Camera System that includes real-time weather observations at San Francisco International Airport. The goal of this research is to develop, deploy, and demonstrate remotely operated cameras and sensors at several major airport hubs and un-towered airports. RTSS can provide real-time weather observations of airport approach zone. RTSS will integrate and test airport sensor packages that will allow remote access to realtime airport conditions and aircraft status.

  2. The Airport Network Flow Simulator.

    DOT National Transportation Integrated Search

    1976-05-01

    The impact of investment at an individual airport is felt through-out the National Airport System by reduction of delays at other airports in the the system. A GPSS model was constructed to simulate the propagation of delays through a nine-airport sy...

  3. Airport Ground Access Study

    DOT National Transportation Integrated Search

    1978-03-02

    In response to a request by Congress, the FAA and TSC have undertaken a study to determine the extent to which inadequate (off-airport) ground access to airports constrains airport capacity and air travel. Presently, TSC is preparing case studies of ...

  4. A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling.

    PubMed

    Ji, Zhejian; Gao, Haishan; Jia, Luying; Li, Bing; Yu, Hongtao

    2017-01-10

    The master spindle checkpoint kinase Mps1 senses kinetochore-microtubule attachment and promotes checkpoint signaling to ensure accurate chromosome segregation. The kinetochore scaffold Knl1, when phosphorylated by Mps1, recruits checkpoint complexes Bub1-Bub3 and BubR1-Bub3 to unattached kinetochores. Active checkpoint signaling ultimately enhances the assembly of the mitotic checkpoint complex (MCC) consisting of BubR1-Bub3, Mad2, and Cdc20, which inhibits the anaphase-promoting complex or cyclosome bound to Cdc20 (APC/C Cdc20 ) to delay anaphase onset. Using in vitro reconstitution, we show that Mps1 promotes APC/C inhibition by MCC components through phosphorylating Bub1 and Mad1. Phosphorylated Bub1 binds to Mad1-Mad2. Phosphorylated Mad1 directly interacts with Cdc20. Mutations of Mps1 phosphorylation sites in Bub1 or Mad1 abrogate the spindle checkpoint in human cells. Therefore, Mps1 promotes checkpoint activation through sequentially phosphorylating Knl1, Bub1, and Mad1. This sequential multi-target phosphorylation cascade makes the checkpoint highly responsive to Mps1 and to kinetochore-microtubule attachment.

  5. 49 CFR 1544.235 - Training and knowledge for individuals with security-related duties.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... airport security program applicable to their location, and the aircraft operator's security program to the... security-related duties. 1544.235 Section 1544.235 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION...

  6. 49 CFR 1544.235 - Training and knowledge for individuals with security-related duties.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... airport security program applicable to their location, and the aircraft operator's security program to the... security-related duties. 1544.235 Section 1544.235 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION...

  7. 49 CFR 1544.235 - Training and knowledge for individuals with security-related duties.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... airport security program applicable to their location, and the aircraft operator's security program to the... security-related duties. 1544.235 Section 1544.235 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION...

  8. 49 CFR 1544.235 - Training and knowledge for individuals with security-related duties.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... airport security program applicable to their location, and the aircraft operator's security program to the... security-related duties. 1544.235 Section 1544.235 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION...

  9. 76 FR 31823 - Technical Amendment to List of User Fee Airports: Addition of Dallas Love Field Municipal Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ...] Technical Amendment to List of User Fee Airports: Addition of Dallas Love Field Municipal Airport, Dallas... fee airport designation for Dallas Love Field Municipal Airport, in Dallas, Texas. User fee airports... Love Field Municipal Airport. This document updates the list of user fee airports by adding Dallas Love...

  10. Occupational Exposure to Ultrafine Particles among Airport Employees - Combining Personal Monitoring and Global Positioning System

    PubMed Central

    Møller, Karina Lauenborg; Thygesen, Lau Caspar; Schipperijn, Jasper; Loft, Steffen; Bonde, Jens Peter; Mikkelsen, Sigurd; Brauer, Charlotte

    2014-01-01

    Background Exposure to ultrafine particles (UFP) has been linked to cardiovascular and lung diseases. Combustion of jet fuel and diesel powered handling equipment emit UFP resulting in potentially high exposure levels among employees working at airports. High levels of UFP have been reported at several airports, especially on the apron, but knowledge on individual exposure profiles among different occupational groups working at an airport is lacking. Purpose The aim of this study was to compare personal exposure to UFP among five different occupational groups working at Copenhagen Airport (CPH). Method 30 employees from five different occupational groups (baggage handlers, catering drivers, cleaning staff and airside and landside security) at CPH were instructed to wear a personal monitor of particle number concentration in real time and a GPS device. The measurements were carried out on 8 days distributed over two weeks in October 2012. The overall differences between the groups were assessed using linear mixed model. Results Data showed significant differences in exposure levels among the groups when adjusted for variation within individuals and for effect of time and date (p<0.01). Baggage handlers were exposed to 7 times higher average concentrations (geometric mean, GM: 37×103 UFP/cm3, 95% CI: 25–55×103 UFP/cm3) than employees mainly working indoors (GM: 5×103 UFP/cm3, 95% CI: 2–11×103 UFP/cm3). Furthermore, catering drivers, cleaning staff and airside security were exposed to intermediate concentrations (GM: 12 to 20×103 UFP/cm3). Conclusion The study demonstrates a strong gradient of exposure to UFP in ambient air across occupational groups of airport employees. PMID:25203510

  11. Occupational exposure to ultrafine particles among airport employees--combining personal monitoring and global positioning system.

    PubMed

    Møller, Karina Lauenborg; Thygesen, Lau Caspar; Schipperijn, Jasper; Loft, Steffen; Bonde, Jens Peter; Mikkelsen, Sigurd; Brauer, Charlotte

    2014-01-01

    Exposure to ultrafine particles (UFP) has been linked to cardiovascular and lung diseases. Combustion of jet fuel and diesel powered handling equipment emit UFP resulting in potentially high exposure levels among employees working at airports. High levels of UFP have been reported at several airports, especially on the apron, but knowledge on individual exposure profiles among different occupational groups working at an airport is lacking. The aim of this study was to compare personal exposure to UFP among five different occupational groups working at Copenhagen Airport (CPH). 30 employees from five different occupational groups (baggage handlers, catering drivers, cleaning staff and airside and landside security) at CPH were instructed to wear a personal monitor of particle number concentration in real time and a GPS device. The measurements were carried out on 8 days distributed over two weeks in October 2012. The overall differences between the groups were assessed using linear mixed model. Data showed significant differences in exposure levels among the groups when adjusted for variation within individuals and for effect of time and date (p<0.01). Baggage handlers were exposed to 7 times higher average concentrations (geometric mean, GM: 37×103 UFP/cm(3), 95% CI: 25-55 × 10(3) UFP/cm(3)) than employees mainly working indoors (GM: 5 × 10(3) UFP/cm(3), 95% CI: 2-11 × 103 UFP/cm(3)). Furthermore, catering drivers, cleaning staff and airside security were exposed to intermediate concentrations (GM: 12 to 20 × 10(3) UFP/cm(3)). The study demonstrates a strong gradient of exposure to UFP in ambient air across occupational groups of airport employees.

  12. 78 FR 7476 - Airport Improvement Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... of Airport Planning and Programming, Financial Assistance Division has updated and significantly.... San Martin, Manager, Airports Financial Assistance Division, Office of Airport Planning and... Airports, Airport Planning and Programming, Routing Symbol APP-501, 800 Independence Avenue SW., Room 619...

  13. The impact of airport characteristics on airport surface accidents and incidents.

    PubMed

    Wilke, Sabine; Majumdar, Arnab; Ochieng, Washington Y

    2015-06-01

    Airport surface safety and in particular runway and taxiway safety is acknowledged globally as one of aviation's greatest challenges. To improve this key area of aviation safety, it is necessary to identify and understand the causal and contributing factors on safety occurrences. While the contribution of human factors, operations, and procedures has been researched extensively, the impact of the airport and its associated characteristics itself has received little or no attention. This paper introduces a novel methodology for risk and hazard assessment of airport surface operations, and models the relationships between airport characteristics, and (a) the rate of occurrences, (b) the severity of occurrences, and (c) the causal factors underlying occurrences. The results show for the first time how the characteristics of airports, and in particular its infrastructure and operations, influence the safety of surface operations. Copyright © 2015 Elsevier Ltd. and National Safety Council. Published by Elsevier Ltd. All rights reserved.

  14. Louisiana Airport System Plan.

    DOT National Transportation Integrated Search

    1992-10-01

    This report is a non-technical summary of the update to the Louisiana Airport System Plan. The system plan identifies the location, service level, and role of the 81 airports included in the plan and the costs to develop individual airports and the a...

  15. Airport Network Flow Simulator

    DOT National Transportation Integrated Search

    1978-10-01

    The Airport Network Flow Simulator is a FORTRAN IV simulation of the flow of air traffic in the nation's 600 commercial airports. It calculates for any group of selected airports: (a) the landing and take-off (Type A) delays; and (b) the gate departu...

  16. 77 FR 51948 - Airport Improvement Program (AIP): Policy Regarding Access to Airports From Residential Property...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ...-0754] Airport Improvement Program (AIP): Policy Regarding Access to Airports From Residential Property... Airports From Residential Property that was published in the Federal Register on July 30, 2012. The FAA is... policy, based on Federal law, concerning through-the- fence access to a federally obligated airport from...

  17. 14 CFR 141.38 - Airports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Airports. 141.38 Section 141.38 Aeronautics... CERTIFICATED AGENCIES PILOT SCHOOLS Personnel, Aircraft, and Facilities Requirements § 141.38 Airports. (a) An... has continuous use of each airport at which training flights originate. (b) Each airport used for...

  18. 14 CFR 141.38 - Airports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Airports. 141.38 Section 141.38 Aeronautics... CERTIFICATED AGENCIES PILOT SCHOOLS Personnel, Aircraft, and Facilities Requirements § 141.38 Airports. (a) An... has continuous use of each airport at which training flights originate. (b) Each airport used for...

  19. 14 CFR 141.38 - Airports.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Airports. 141.38 Section 141.38 Aeronautics... CERTIFICATED AGENCIES PILOT SCHOOLS Personnel, Aircraft, and Facilities Requirements § 141.38 Airports. (a) An... has continuous use of each airport at which training flights originate. (b) Each airport used for...

  20. 14 CFR 141.38 - Airports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Airports. 141.38 Section 141.38 Aeronautics... CERTIFICATED AGENCIES PILOT SCHOOLS Personnel, Aircraft, and Facilities Requirements § 141.38 Airports. (a) An... has continuous use of each airport at which training flights originate. (b) Each airport used for...

  1. Endocrinological side-effects of immune checkpoint inhibitors.

    PubMed

    Torino, Francesco; Corsello, Salvatore M; Salvatori, Roberto

    2016-07-01

    Three mAbs targeting immune checkpoint proteins are available for the treatment of patients with melanoma, lung, and kidney cancer, and their use will likely expand in the future to additional tumor types. We here update the literature on the incidence and pathophysiology of endocrine toxicities induced by these agents, and discuss management guidance. Immune checkpoint inhibition may trigger autoimmune syndromes involving different organs, including several endocrine glands (pituitary, thyroid, adrenals, and endocrine pancreas). Hypophysitis is more frequently associated with ipilimumab, whereas the incidence of thyroid dysfunction is higher with nivolumab/pembrolizumab. Primary adrenal insufficiency can rarely occur with either treatment. Autoimmune diabetes is very rare. As hypophysitis and adrenalitis may be life-threatening, endocrinological evaluation is essential particularly in patients developing fatigue and other symptoms consistent with adrenal insufficiency. Corticosteroids should be promptly used when hypophysitis-induced adrenal insufficiency or adrenalitis are diagnosed, but not in thyroiditis or diabetes. No impact of corticosteroids on the efficacy/activity of immune checkpoint-inhibiting drugs is reported. Hormonal deficiencies are often permanent. In absence of predicting factors, accurate information to patients provided by the oncology care team is essential for early diagnosis and to limit the consequences of checkpoint inhibition-related endocrine toxicity.

  2. A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling

    PubMed Central

    Ji, Zhejian; Gao, Haishan; Jia, Luying; Li, Bing; Yu, Hongtao

    2017-01-01

    The master spindle checkpoint kinase Mps1 senses kinetochore-microtubule attachment and promotes checkpoint signaling to ensure accurate chromosome segregation. The kinetochore scaffold Knl1, when phosphorylated by Mps1, recruits checkpoint complexes Bub1–Bub3 and BubR1–Bub3 to unattached kinetochores. Active checkpoint signaling ultimately enhances the assembly of the mitotic checkpoint complex (MCC) consisting of BubR1–Bub3, Mad2, and Cdc20, which inhibits the anaphase-promoting complex or cyclosome bound to Cdc20 (APC/CCdc20) to delay anaphase onset. Using in vitro reconstitution, we show that Mps1 promotes APC/C inhibition by MCC components through phosphorylating Bub1 and Mad1. Phosphorylated Bub1 binds to Mad1–Mad2. Phosphorylated Mad1 directly interacts with Cdc20. Mutations of Mps1 phosphorylation sites in Bub1 or Mad1 abrogate the spindle checkpoint in human cells. Therefore, Mps1 promotes checkpoint activation through sequentially phosphorylating Knl1, Bub1, and Mad1. This sequential multi-target phosphorylation cascade makes the checkpoint highly responsive to Mps1 and to kinetochore-microtubule attachment. DOI: http://dx.doi.org/10.7554/eLife.22513.001 PMID:28072388

  3. Low-manpower checkpoints: can they provide effective DUI enforcement in small communities?

    PubMed

    Lacey, John H; Ferguson, Susan A; Kelley-Baker, Tara; Rider, Raamses P

    2006-09-01

    Sobriety checkpoints can be effective in reducing alcohol-impaired driving. Checkpoints are underutilized, however, partially because police believe a large number of officers are required. This study evaluated the feasibility and impact of conducting small-scale checkpoints in rural communities. Law enforcement agencies in two counties agreed to conduct weekly checkpoints for one year. Two nonadjacent counties did not undertake additional checkpoints. Evaluation included public-awareness surveys and roadside surveys (including blood alcohol concentration [BAC] measurements) of weekend nighttime drivers. Relative to drivers in the comparison counties, the proportion of drivers in the experimental counties with BACs >0.05% was 70% lower. Drivers surveyed at driver's license offices in the experimental counties after program implementation were more likely to report seeing or passing through a checkpoint and were more aware of publicity on driving under the influence (DUI) enforcement. Small rural communities can safely and effectively conduct low-staff sobriety checkpoints on a weekly basis. Such programs can be expected to result in large reductions in drivers operating at higher BACs.

  4. The human intra-S checkpoint response to UVC-induced DNA damage.

    PubMed

    Kaufmann, William K

    2010-05-01

    The intra-S checkpoint response to 254 nm light (UVC)-induced DNA damage appears to have dual functions to slow the rate of DNA synthesis and stabilize replication forks that become stalled at sites of UVC-induced photoproducts in DNA. These functions should provide more time for repair of damaged DNA before its replication and thereby reduce the frequencies of mutations and chromosomal aberrations in surviving cells. This review tries to summarize the history of discovery of the checkpoint, the current state of understanding of the biological features of intra-S checkpoint signaling and its mechanisms of action with a focus primarily on intra-S checkpoint responses in human cells. The differences in the intra-S checkpoint responses to UVC and ionizing radiation-induced DNA damage are emphasized. Evidence that [6-4]pyrimidine-pyrimidone photoproducts in DNA trigger the response is discussed and the relationships between cellular responses to UVC and the molecular dose of UVC-induced DNA damage are briefly summarized. The role of the intra-S checkpoint response in protecting against solar radiation carcinogenesis remains to be determined.

  5. Orchestration of DNA Damage Checkpoint Dynamics across the Human Cell Cycle.

    PubMed

    Chao, Hui Xiao; Poovey, Cere E; Privette, Ashley A; Grant, Gavin D; Chao, Hui Yan; Cook, Jeanette G; Purvis, Jeremy E

    2017-11-22

    Although molecular mechanisms that prompt cell-cycle arrest in response to DNA damage have been elucidated, the systems-level properties of DNA damage checkpoints are not understood. Here, using time-lapse microscopy and simulations that model the cell cycle as a series of Poisson processes, we characterize DNA damage checkpoints in individual, asynchronously proliferating cells. We demonstrate that, within early G1 and G2, checkpoints are stringent: DNA damage triggers an abrupt, all-or-none cell-cycle arrest. The duration of this arrest correlates with the severity of DNA damage. After the cell passes commitment points within G1 and G2, checkpoint stringency is relaxed. By contrast, all of S phase is comparatively insensitive to DNA damage. This checkpoint is graded: instead of halting the cell cycle, increasing DNA damage leads to slower S phase progression. In sum, we show that a cell's response to DNA damage depends on its exact cell-cycle position and that checkpoints are phase-dependent, stringent or relaxed, and graded or all-or-none. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Office of Inspector General Audit Report: Accountability and Use of Airport Revenues Queen City Municipal Airport

    DOT National Transportation Integrated Search

    1997-01-30

    The objective of the audit was to determine the validity of allegations that the city of Allentown, Pennsylvania (Sponsor), diverted airport revenues. Specifically, airport users alleged the Sponsor (i) sold Queen City Municipal Airport (airport) lan...

  7. Metropolitan Washington Airports Authority : contracting practices do not always comply with airport lease requirements

    DOT National Transportation Integrated Search

    2002-03-01

    The Metropolitan Washington Airports Act of 1986 provided for the lease of Washington Dulles International Airport (Dulles) and Ronald Reagan Washington National Airport (Reagan National)and the transfer of operating responsibility from the federal g...

  8. Aviation Security: Weaknesses in Airport Security and Options for Assigning Screening Responsibilities

    DTIC Science & Technology

    2001-09-21

    actually occurred or which of the weaknesses in the nations aviation security apparatus contributed to the horrendous events of last week, it is...clear that serious weaknesses exist in our aviation security system and that their impact can be far more devastating than previously imagined.

  9. 49 CFR 1549.103 - Qualifications and training of individuals with security-related duties.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Circulars; and (4) The applicable portions of approved airport security program(s) and aircraft operator... security-related duties. 1549.103 Section 1549.103 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION...

  10. 49 CFR 1549.103 - Qualifications and training of individuals with security-related duties.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Circulars; and (4) The applicable portions of approved airport security program(s) and aircraft operator... security-related duties. 1549.103 Section 1549.103 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION...

  11. 49 CFR 1549.103 - Qualifications and training of individuals with security-related duties.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Circulars; and (4) The applicable portions of approved airport security program(s) and aircraft operator... security-related duties. 1549.103 Section 1549.103 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION...

  12. The problem of suspended and revoked drivers who avoid detection at checkpoints.

    PubMed

    Parrish, Kelly E; Masten, Scott V

    2015-01-01

    Although driver license suspension and revocation have been shown to improve traffic safety, suspended or revoked (SR) drivers who continue to drive-which appears to be the majority-are about 3 times more likely to be involved in crashes and to cause a fatal crash. In California and many other U.S. states, drivers are typically mailed notices requesting that they surrender their licenses when they are SR for reasons other than driving under the influence of alcohol or drugs (DUI), yet they frequently do not comply. Typical procedures at DUI checkpoints in California and other U.S. states include inspecting driver licenses and checking for signs of intoxication during brief contacts with law enforcement officers. Hence, these checkpoints are in fact DUI/license checkpoints in California and many other states. The purpose of this study was to estimate the extent to which SR drivers avoid being detected at DUI/license checkpoints for SR driving, because they illegally retained possession of their license cards. Law enforcement officers used electronic license card readers at DUI/license checkpoints in Sacramento, California, to record data for 13,705 drivers. The SR status of all contacted drivers was determined after the checkpoints and compared to law enforcement citation records from the checkpoints. Although only 3% of the drivers contacted at the checkpoints were SR, about 41% of SR drivers were able to pass through undetected because they presented license cards that they illegally retained. Drivers SR for DUI-related reasons were more likely to be detected, whereas those SR for failure to provide proof of financial responsibility (insurance) were less likely to be detected. The fact that many SR drivers are able to pass through DUI/license checkpoints undetected weakens both the specific and general impacts of checkpoints for deterring SR driving and may diminish the effectiveness of suspension and revocation actions for reducing the crash risk posed by problem

  13. Monitoring of Airport Revenues at Arlington Municipal Airport; Federal Aviation Administration Northwest Mountain Region

    DOT National Transportation Integrated Search

    1997-01-15

    The objectives of our audit were to determine whether Federal Aviation : Administration (FAA) monitoring of Arlington Municipal Airport (Airport) was : adequate to ensure (i) a fee and rental structure was maintained which made the : Airport as self-...

  14. Space Reclamation for Uncoordinated Checkpointing in Message-Passing Systems. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Wang, Yi-Min

    1993-01-01

    Checkpointing and rollback recovery are techniques that can provide efficient recovery from transient process failures. In a message-passing system, the rollback of a message sender may cause the rollback of the corresponding receiver, and the system needs to roll back to a consistent set of checkpoints called recovery line. If the processes are allowed to take uncoordinated checkpoints, the above rollback propagation may result in the domino effect which prevents recovery line progression. Traditionally, only obsolete checkpoints before the global recovery line can be discarded, and the necessary and sufficient condition for identifying all garbage checkpoints has remained an open problem. A necessary and sufficient condition for achieving optimal garbage collection is derived and it is proved that the number of useful checkpoints is bounded by N(N+1)/2, where N is the number of processes. The approach is based on the maximum-sized antichain model of consistent global checkpoints and the technique of recovery line transformation and decomposition. It is also shown that, for systems requiring message logging to record in-transit messages, the same approach can be used to achieve optimal message log reclamation. As a final topic, a unifying framework is described by considering checkpoint coordination and exploiting piecewise determinism as mechanisms for bounding rollback propagation, and the applicability of the optimal garbage collection algorithm to domino-free recovery protocols is demonstrated.

  15. Expression of checkpoint molecules on myeloid-derived suppressor cells.

    PubMed

    Ballbach, Marlene; Dannert, Angelika; Singh, Anurag; Siegmund, Darina M; Handgretinger, Rupert; Piali, Luca; Rieber, Nikolaus; Hartl, Dominik

    2017-12-01

    Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population expanded in cancer, infection and autoimmunity capable of suppressing T-cell functions. Checkpoint inhibitors have emerged as a key therapeutic strategy in immune-oncology. While checkpoint molecules were initially associated with T cell functions, recent evidence suggests a broader expression and function in innate myeloid cells. Previous studies provided first evidence for a potential role for checkpoints on MDSCs, yet the human relevance remained poorly understood. Therefore, we investigated the expression and functional relevance of checkpoint molecules in human MDSC-T-cell interactions. Our studies demonstrate that programmed death-ligand 1 (PD-L1) is expressed on granulocytic MDSCs upon co-culture with T cells. Transwell experiments showed that cell-to-cell contact was required for MDSC-T-cell interactions and antibody blocking studies showed that targeting PD-L1 partially impaired MDSC-mediated T-cell suppression. Collectively, these studies suggest a role for PD-L1 in human MDSC function and thereby expand the functionality of this checkpoint beyond T cells, which could pave the way for further understanding and therapeutic targeting of PD-1/PD-L1 in innate immune-mediated diseases. Copyright © 2017 European Federation of Immunological Societies. Published by Elsevier B.V. All rights reserved.

  16. Message Efficient Checkpointing and Rollback Recovery in Heterogeneous Mobile Networks

    NASA Astrophysics Data System (ADS)

    Jaggi, Parmeet Kaur; Singh, Awadhesh Kumar

    2016-06-01

    Heterogeneous networks provide an appealing way of expanding the computing capability of mobile networks by combining infrastructure-less mobile ad-hoc networks with the infrastructure-based cellular mobile networks. The nodes in such a network range from low-power nodes to macro base stations and thus, vary greatly in their capabilities such as computation power and battery power. The nodes are susceptible to different types of transient and permanent failures and therefore, the algorithms designed for such networks need to be fault-tolerant. The article presents a checkpointing algorithm for the rollback recovery of mobile hosts in a heterogeneous mobile network. Checkpointing is a well established approach to provide fault tolerance in static and cellular mobile distributed systems. However, the use of checkpointing for fault tolerance in a heterogeneous environment remains to be explored. The proposed protocol is based on the results of zigzag paths and zigzag cycles by Netzer-Xu. Considering the heterogeneity prevalent in the network, an uncoordinated checkpointing technique is employed. Yet, useless checkpoints are avoided without causing a high message overhead.

  17. Wind shear over the Nice Côte d'Azur airport: case studies

    NASA Astrophysics Data System (ADS)

    Boilley, A.; Mahfouf, J.-F.

    2013-09-01

    The Nice Côte d'Azur international airport is subject to horizontal low-level wind shears. Detecting and predicting these hazards is a major concern for aircraft security. A measurement campaign took place over the Nice airport in 2009 including 4 anemometers, 1 wind lidar and 1 wind profiler. Two wind shear events were observed during this measurement campaign. Numerical simulations were carried out with Meso-NH in a configuration compatible with near-real time applications to determine the ability of the numerical model to predict these events and to study the meteorological situations generating an horizontal wind shear. A comparison between numerical simulation and the observation dataset is conducted in this paper.

  18. Wind shear over the Nice Côte d'Azur airport: case studies

    NASA Astrophysics Data System (ADS)

    Boilley, A.; Mahfouf, J.-F.

    2013-04-01

    The Nice Côte d'Azur international airport is subject to horizontal low-level wind shears. Detecting and predicting these hazards is a major concern for aircraft security. A measurement campaign took place over the Nice airport in 2009 including 4 anemometers, 1 wind lidar and 1 wind profiler. Two wind shear events were observed during this measurement campaign. Numerical simulations were carried out with Meso-NH in a configuration compatible with near-real time applications to determine the ability of the numerical model to predict these events and to study the meteorological situations generating a horizontal wind shear. A comparison between numerical simulation and the observation dataset is conducted in this paper.

  19. Sobriety checkpoints in Thailand: a review of effectiveness and developments over time.

    PubMed

    Ditsuwan, Vallop; Veerman, J Lennert; Bertram, Melanie; Vos, Theo

    2015-03-01

    This review describes the legal basis for and implementation of sobriety checkpoints in Thailand and identifies factors that influenced their historical development and effectiveness. The first alcohol and traffic injury control law in Thailand was implemented in 1934. The 0.05 g/100 mL blood alcohol concentration limit was set in 1994. Currently, 3 types of sobriety checkpoints are used: general police checkpoints, selective breath testing, and special event sobriety checkpoints. The authors found few reports on the strategies, frequencies, and outcomes for any of these types of checkpoints, despite Thailand having devoted many resources to their implementation. In Thailand and other low-middle income countries, it is necessary to address the country-specific barriers to successful enforcement (including political and logistical issues, lack of equipment, and absence of other supportive alcohol harm reduction measures) before sobriety checkpoints can be expected to be as effective as reported in high-income countries. © 2011 APJPH.

  20. Intelligent building system for airport

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ancevic, M.

    1997-11-01

    The Munich airport uses a state-of-the-art intelligent building management system to control systems such as HVAC, runway lights, baggage handling, etc. Planning the new Munich II international airport provided a unique opportunity to use the latest state-of-the-art technical systems, while integrating their control through a single intelligent building management system. Opened in 1992, the airport is Germany`s second-largest airport after Frankfurt. The airport is staffed by 16,000 employees and can handle 17 million passengers a year. The sprawling site encompasses more than 120 buildings. The airport`s distributed control system is specifically designed to optimize the complex`s unique range of functions,more » while providing a high degree of comfort, convenience and safety for airport visitors. With the capacity to control 200,000 points, this system controls more than 112,000 points and integrates 13 major subsystems from nine different vendors. It provides convenient, accessible control of everything including the complex`s power plant, HVAC Control, the terminal`s people-moving functions, interior lighting controls, runway lights, baggage forwarding systems, elevators, and boarding bridges. The airport was named 1993 intelligent building of the year by the Intelligent Buildings Institute Foundation. Its building management system is a striking example of the degree to which a building complex`s functions can be integrated for greater operational control and efficiency.« less

  1. Human cytomegalovirus inhibits a DNA damage response by mislocalizing checkpoint proteins

    NASA Astrophysics Data System (ADS)

    Gaspar, Miguel; Shenk, Thomas

    2006-02-01

    The DNA damage checkpoint pathway responds to DNA damage and induces a cell cycle arrest to allow time for DNA repair. Several viruses are known to activate or modulate this cellular response. Here we show that the ataxia-telangiectasia mutated checkpoint pathway, which responds to double-strand breaks in DNA, is activated in response to human cytomegalovirus DNA replication. However, this activation does not propagate through the pathway; it is blocked at the level of the effector kinase, checkpoint kinase 2 (Chk2). Late after infection, several checkpoint proteins, including ataxia-telangiectasia mutated and Chk2, are mislocalized to a cytoplasmic virus assembly zone, where they are colocalized with virion structural proteins. This colocalization was confirmed by immunoprecipitation of virion proteins with an antibody that recognizes Chk2. Virus replication was resistant to ionizing radiation, which causes double-strand breaks in DNA. We propose that human CMV DNA replication activates the checkpoint response to DNA double-strand breaks, and the virus responds by altering the localization of checkpoint proteins to the cytoplasm and thereby inhibiting the signaling pathway. ionizing radiation | ataxia-telangiectasia mutated pathway

  2. Airport activity and noise trends

    DOT National Transportation Integrated Search

    1993-10-01

    This report is published by the Metropolitan Transportation Commission : (MTC) to provide information concerning local Bay Area airport activity and : airport noise trends. The airport activity data are obtained from published : airline schedules and...

  3. Airport Landside. Volume I. Planning Guide.

    DOT National Transportation Integrated Search

    1982-01-01

    This volume describes a methodology for performing airport landside planning by applying the Airport Landside Simulation Model (ALSIM) developed by TSC. For this analysis, the airport landside is defined as extending from the airport boundary to the ...

  4. 76 FR 69321 - Intent To Rule On Request To Release Airport Property at the Malden Regional Airport and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... Airport Property at the Malden Regional Airport and Industrial Park (MAW), Malden, MO AGENCY: Federal... comment on the release of land at the Malden Regional Airport & Industrial Park (MAW), Malden, Missouri... address: Lynn D. Martin, Airports Compliance Specialist, Federal Aviation Administration, Airports...

  5. Approved Airport Equipment

    DOT National Transportation Integrated Search

    1997-06-06

    This advisory circular (AC) administratively cancels AC 150/5345-1U, Approved : Airport Equipment dated February 20, 1989, and directs replacement of any : reference to AC 150/5345-1 with AC 150/5345-53, Airport Lighting Equipment : Certification Pro...

  6. Checkpoints: it takes more than time to heal some wounds.

    PubMed

    Rhind, N; Russell, P

    The S-phase DNA damage checkpoint seems to provide a twist on the checkpoint theme. Instead of delaying replication and allowing repair as a consequence, it may activate repair and delay replication as a consequence.

  7. The performance of spatially offset Raman spectroscopy for liquid explosive detection

    NASA Astrophysics Data System (ADS)

    Loeffen, Paul W.; Maskall, Guy; Bonthron, Stuart; Bloomfield, Matthew; Tombling, Craig; Matousek, Pavel

    2016-10-01

    Aviation security requirements adopted in 2014 require liquids to be screened at most airports throughout Europe, North America and Australia. Cobalt's unique Spatially Offset Raman Spectroscopy (SORS™) technology has proven extremely effective at screening liquids, aerosols and gels (LAGS) with extremely low false alarm rates. SORS is compatible with a wide range of containers, including coloured, opaque or clear plastics, glass and paper, as well as duty-free bottles in STEBs (secure tamper-evident bags). Our award-winning Insight range has been specially developed for table-top screening at security checkpoints. Insight systems use our patented SORS technology for rapid and accurate chemical analysis of substances in unopened non-metallic containers. Insight100M™ and the latest member of the range - Insight200M™ - also screen metallic containers. Our unique systems screen liquids, aerosols and gels with the highest detection capability and lowest false alarm rates of any ECAC-approved scanner, with several hundred units already in use at airports including eight of the top ten European hubs. This paper presents an analysis of real performance data for these systems.

  8. Aviation Security: Slow Progress in Addressing Long-Standing Screener Performance Problems

    DTIC Science & Technology

    2000-03-16

    aviation security , in particular airport screeners. Securing an air transportation system the size of this nation’s-with hundreds of airports, thousands of aircraft, and tens of thousands of flights daily carrying millions of passengers and pieces of baggage-is a difficult task. Events over the past decade have shown that the threat of terrorism against the United States is an ever-present danger. Aviation is an attractive target for terrorists, and because the air transportation system is critical to the nation’s well-being, protecting it is an important

  9. Checkpoint Inhibition in Hodgkin Lymphoma - a Review.

    PubMed

    Bröckelmann, Paul J; Engert, Andreas

    2017-01-01

    Physiological immune checkpoint pathways are important to regulate self-tolerance, limit immune reactions, and moderate autoimmunity. Various cancers are commonly exploiting these mechanisms to evade the host immune system by restraining a durable, efficient anti-tumor immune response. Immune checkpoints include, but are not limited to, the programmed death 1 (PD1) and the cytotoxic T-lymphocyte-associated protein-4 (CTLA4) axis, which are both druggable by monoclonal antibodies referred to as checkpoint inhibitors (CIs). To date, the anti-PD1 antibodies nivolumab and pembrolizumab are approved for relapsed or refractory classical Hodgkin lymphoma (cHL) due to high response rates with a favorable yet distinct safety profile, and other agents are under investigation. This review summarizes the available preclinical and clinical data including the toxicity and efficacy of different CIs in cHL. It also provides future perspectives based on ongoing clinical trials, potentially synergistic combinatory approaches, and their fit in the therapeutic landscape in cHL. © 2017 S. Karger GmbH, Freiburg.

  10. Checkpoints: It takes more than time to heal some wounds

    PubMed Central

    Rhind, Nicholas; Russell, Paul

    2010-01-01

    The S-phase DNA damage checkpoint seems to provide a twist on the checkpoint theme. Instead of delaying replication and allowing repair as a consequence, it may activate repair and delay replication as a consequence. PMID:11137027

  11. [Genetic Mutation Accumulation and Clinical Outcome of Immune Checkpoint Blockade Therapy].

    PubMed

    Takahashi, Masanobu

    2016-06-01

    Immune checkpoint blockade therapy has recently attracted great attention in the area of oncology. In Japan, since 2014, an anti-PD-1 antibody nivolumab and anti-CTLA-4 antibody ipilimumab have been available for the treatment of patients with malignant melanoma, and nivolumab has been available for patients with non-small cell lung cancer. Clinical trials using these drugs and other immune checkpoint inhibitors are currently in progress worldwide. The immune checkpoint blockade therapy is a promising new cancer therapy; however, not all patients with cancer can benefit from this therapy. Recent evidence shows that markers reflecting the extent of genetic mutation accumulation, including mutation burden, non-synonymous mutation that produces neoantigen, and microsatellite instability, possibly serve as promising marker to predict who can benefit from the immune checkpoint blockade therapy. Here, I introduce the recent evidence and discuss the correlation between genetic mutation accumulation and clinical outcome of immune checkpoint blockade therapy.

  12. Airport Ground Access Planning Guide

    DOT National Transportation Integrated Search

    1980-07-01

    Airport access has been identified by some airport authorities as a potential threat to the growth of aviation. In order to help airport planners and local authorities define the critical elements of an access problem and identify improvement project...

  13. Airport Capacity Enhancement Plan.

    DTIC Science & Technology

    1986-01-01

    capacity and efficiency of airports without sacrificing safety and enviromental concerns. PA L. 0t- ~I|| TABLE OF CONTENTS SECTION Page EXECUTIVE...environmental, and socio - political factors. These constraints include the following: * The construction of new airports and the expansion of the...inter-airport conflicts . In New he York, for example, an MLS installation at LaGuardia ns could reduce some arrival route lengths significantly, ’.@rts

  14. 49 CFR 27.71 - Airport facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Airport facilities. 27.71 Section 27.71... Administration Programs: Airports, Railroads, and Highways § 27.71 Airport facilities. (a) This section applies... financial assistance at a commercial service airport, including parking and ground transportation facilities...

  15. 49 CFR 27.71 - Airport facilities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Airport facilities. 27.71 Section 27.71... Administration Programs: Airports, Railroads, and Highways § 27.71 Airport facilities. (a) This section applies... financial assistance at a commercial service airport, including parking and ground transportation facilities...

  16. 49 CFR 27.71 - Airport facilities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Airport facilities. 27.71 Section 27.71... Administration Programs: Airports, Railroads, and Highways § 27.71 Airport facilities. (a) This section applies... financial assistance at a commercial service airport, including parking and ground transportation facilities...

  17. U.S. Airport Greenhouse Gas Emissions Inventories: State of the Practice and Recommendations for Airports.

    DOT National Transportation Integrated Search

    2016-03-01

    This document presents highlights from five research reports on airport greenhouse gas (GHG) emissions inventories. It presents the most salient findings for policy makers and U.S. airports seeking to better understand and inventory airport GHG emiss...

  18. Analysis of the Demand for Airport Bus Services at Washington National and Dulles International Airports

    DOT National Transportation Integrated Search

    1984-05-01

    This report presents the findings and recommendations from a study of the demand for airport bus services at Washington National and Dulles International Airports. The purpose of the study was to provide FAA's Metropolitan Washington Airports with a ...

  19. Phenotypic Checkpoints Regulate Neuronal Development

    PubMed Central

    Ben-Ari, Yehezkel; Spitzer, Nicholas C.

    2010-01-01

    Nervous system development proceeds by sequential gene expression mediated by cascades of transcription factors in parallel with sequences of patterned network activity driven by receptors and ion channels. These sequences are cell type- and developmental stage-dependent and modulated by paracrine actions of substances released by neurons and glia. How and to what extent these sequences interact to enable neuronal network development is not understood. Recent evidence demonstrates that CNS development requires intermediate stages of differentiation providing functional feedback that influences gene expression. We suggest that embryonic neuronal functions constitute a series of phenotypic checkpoint signatures; neurons failing to express these functions are delayed or developmentally arrested. Such checkpoints are likely to be a general feature of neuronal development and may constitute presymptomatic signatures of neurological disorders when they go awry. PMID:20864191

  20. 75 FR 57829 - Airport Improvement Program (AIP): Policy Regarding Access to Airports From Residential Property

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration [Docket No. FAA-2010-0831] Airport Improvement Program (AIP): Policy Regarding Access to Airports From Residential Property AGENCY: Federal... inadvertent omission in the Privacy paragraph in the Notice of Proposed Policy Regarding Access to Airports...

  1. 75 FR 78262 - Intent To Request Approval From OMB of One New Public Collection of Information: Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-15

    ...The Transportation Security Administration (TSA) invites public comment on a new Information Collection Request (ICR) (abstracted below) that we will submit to the Office of Management and Budget (OMB) for approval in compliance with the Paperwork Reduction Act (PRA). The ICR describes the nature of the information collection and its expected burden. The collection involves the airport operator submitting a Statement of Interest (SOI) and a Federalization Request Letter (FRL) to request that TSA provide passenger and baggage screening services, that is, ``Federalization'' of an airport.

  2. Development of cell-cycle checkpoint therapy for solid tumors.

    PubMed

    Tamura, Kenji

    2015-12-01

    Cellular proliferation is tightly controlled by several cell-cycle checkpoint proteins. In cancer, the genes encoding these proteins are often disrupted and cause unrestrained cancer growth. The proteins are over-expressed in many malignancies; thus, they are potential targets for anti-cancer therapies. These proteins include cyclin-dependent kinase, checkpoint kinase, WEE1 kinase, aurora kinase and polo-like kinase. Cyclin-dependent kinase inhibitors are the most advanced cell-cycle checkpoint therapeutics available. For instance, palbociclib (PD0332991) is a first-in-class, oral, highly selective inhibitor of CDK4/6 and, in combination with letrozole (Phase II; PALOMA-1) or with fulvestrant (Phase III; PALOMA-3), it has significantly prolonged progression-free survival, in patients with metastatic estrogen receptor-positive, HER2-negative breast cancer, in comparison with that observed in patients using letrozole, or fulvestrant alone, respectively. In this review, we provide an overview of the current compounds available for cell-cycle checkpoint protein-directed therapy for solid tumors. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. 14 CFR 152.103 - Sponsors: Airport development.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Sponsors: Airport development. 152.103... (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.103 Sponsors: Airport development. (a) To be eligible to apply for a project for airport development with...

  4. 14 CFR 152.103 - Sponsors: Airport development.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Sponsors: Airport development. 152.103... (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.103 Sponsors: Airport development. (a) To be eligible to apply for a project for airport development with...

  5. 14 CFR 152.103 - Sponsors: Airport development.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Sponsors: Airport development. 152.103... (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.103 Sponsors: Airport development. (a) To be eligible to apply for a project for airport development with...

  6. Distinct chromosome segregation roles for spindle checkpoint proteins.

    PubMed

    Warren, Cheryl D; Brady, D Michelle; Johnston, Raymond C; Hanna, Joseph S; Hardwick, Kevin G; Spencer, Forrest A

    2002-09-01

    The spindle checkpoint plays a central role in the fidelity of chromosome transmission by ensuring that anaphase is initiated only after kinetochore-microtubule associations of all sister chromatid pairs are complete. In this study, we find that known spindle checkpoint proteins do not contribute equally to chromosome segregation fidelity in Saccharomyces cerevisiae. Loss of Bub1 or Bub3 protein elicits the largest effect. Analysis of Bub1p reveals the presence of two molecular functions. An N-terminal 608-amino acid (nonkinase) portion of the protein supports robust checkpoint activity, and, as expected, contributes to chromosome segregation. A C-terminal kinase-encoding segment independently contributes to chromosome segregation through an unknown mechanism. Both molecular functions depend on association with Bub3p. A 156-amino acid fragment of Bub1p functions in Bub3p binding and in kinetochore localization by one-hybrid assay. An adjacent segment is required for Mad1p binding, detected by deletion analysis and coimmunoprecipitation. Finally, overexpression of wild-type BUB1 or MAD3 genes leads to chromosome instability. Analysis of this activity indicates that the Bub3p-binding domain of Bub1p contributes to this phenotype through disruption of checkpoint activity as well as through introduction of kinetochore or spindle damage.

  7. Distinct Chromosome Segregation Roles for Spindle Checkpoint Proteins

    PubMed Central

    Warren, Cheryl D.; Brady, D. Michelle; Johnston, Raymond C.; Hanna, Joseph S.; Hardwick, Kevin G.; Spencer, Forrest A.

    2002-01-01

    The spindle checkpoint plays a central role in the fidelity of chromosome transmission by ensuring that anaphase is initiated only after kinetochore-microtubule associations of all sister chromatid pairs are complete. In this study, we find that known spindle checkpoint proteins do not contribute equally to chromosome segregation fidelity in Saccharomyces cerevisiae. Loss of Bub1 or Bub3 protein elicits the largest effect. Analysis of Bub1p reveals the presence of two molecular functions. An N-terminal 608-amino acid (nonkinase) portion of the protein supports robust checkpoint activity, and, as expected, contributes to chromosome segregation. A C-terminal kinase-encoding segment independently contributes to chromosome segregation through an unknown mechanism. Both molecular functions depend on association with Bub3p. A 156-amino acid fragment of Bub1p functions in Bub3p binding and in kinetochore localization by one-hybrid assay. An adjacent segment is required for Mad1p binding, detected by deletion analysis and coimmunoprecipitation. Finally, overexpression of wild-type BUB1 or MAD3 genes leads to chromosome instability. Analysis of this activity indicates that the Bub3p-binding domain of Bub1p contributes to this phenotype through disruption of checkpoint activity as well as through introduction of kinetochore or spindle damage. PMID:12221113

  8. An ATM-independent S-phase checkpoint response involves CHK1 pathway

    NASA Technical Reports Server (NTRS)

    Zhou, Xiang-Yang; Wang, Xiang; Hu, Baocheng; Guan, Jun; Iliakis, George; Wang, Ya

    2002-01-01

    After exposure to genotoxic stress, proliferating cells actively slow down the DNA replication through a S-phase checkpoint to provide time for repair. We report that in addition to the ataxia-telangiectasia mutated (ATM)-dependent pathway that controls the fast response, there is an ATM-independent pathway that controls the slow response to regulate the S-phase checkpoint after ionizing radiation in mammalian cells. The slow response of S-phase checkpoint, which is resistant to wortmannin, sensitive to caffeine and UCN-01, and related to cyclin-dependent kinase phosphorylation, is much stronger in CHK1 overexpressed cells, and it could be abolished by Chk1 antisense oligonucleotides. These results provide evidence that the ATM-independent slow response of S-phase checkpoint involves CHK1 pathway.

  9. An origin-deficient yeast artificial chromosome triggers a cell cycle checkpoint.

    PubMed

    van Brabant, A J; Buchanan, C D; Charboneau, E; Fangman, W L; Brewer, B J

    2001-04-01

    Checkpoint controls coordinate entry into mitosis with the completion of DNA replication. Depletion of nucleotide precursors by treatment with the drug hydroxyurea triggers such a checkpoint response. However, it is not clear whether the signal for this hydroxyurea-induced checkpoint pathway is the presence of unreplicated DNA, or rather the persistence of single-stranded or damaged DNA. In a yeast artificial chromosome (YAC) we have engineered an approximately 170 kb region lacking efficient replication origins that allows us to explore the specific effects of unreplicated DNA on cell cycle progression. Replication of this YAC extends the length of S phase and causes cells to engage an S/M checkpoint. In the absence of Rad9 the YAC becomes unstable, undergoing deletions within the origin-free region.

  10. Airport Careers. Aviation Careers Series. Revised.

    ERIC Educational Resources Information Center

    Zaharevitz, Walter

    This booklet, one in a series on aviation careers, outlines the variety of careers available in airports. The first part of the booklet provides general information about careers at airports, while the main part of the booklet outlines the following nine job categories: airport director, assistant airport director, engineers, support personnel,…

  11. 14 CFR 151.3 - National Airport Plan.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false National Airport Plan. 151.3 Section 151.3 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS FEDERAL AID TO AIRPORTS General Requirements § 151.3 National Airport Plan. (a) Under the Federal Airport...

  12. 14 CFR 151.3 - National Airport Plan.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false National Airport Plan. 151.3 Section 151.3 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS FEDERAL AID TO AIRPORTS General Requirements § 151.3 National Airport Plan. (a) Under the Federal Airport...

  13. Assessing coastal flood risk and sea level rise impacts at New York City area airports

    NASA Astrophysics Data System (ADS)

    Ohman, K. A.; Kimball, N.; Osler, M.; Eberbach, S.

    2014-12-01

    's understanding of the effects of sea level rise on coastal flooding at the airports and guiding decision-making in the selection of effective adaptation actions. Given the importance of these airports to transportation, this project is advancing security and continuity of national and international commerce well into the 21st century.

  14. Implementation of noise budgets for civil airports

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bishop, D.E.

    1982-01-01

    An increasing number of airports are faced with the need for establishing a lid on the noise from aircraft operations and for developing programs for reducing airport noise on a year-to-year basis. As an example, the California Airport Noise Standard acts to impose such programs on a number of airports in California. Any airport faced with the need to establish a quantitative reduction of noise obviously wants to achieve this reduction with the least impact on numbers of operations and reduction in air transportation services to the community. A reduction in noise and an increase in operations usually can bemore » achieved only by encouraging use of the quietest aircraft available and, further adding incentives for operating procedures that minimize noise. One approach in administering airport noise reduction is to adopt an airport noise budget. As used in this paper, the noise budget concept implies that quantitative limits on the noise environment and on the noise contributions by major airport users will be established. Having methods for enforcing compliance with the airport budget for those airport users that exceed their budget will be established. Thus, the noise budget provides airport management, and major airport users, with quantitative measures for defining noise goals, and actual progress in achieving such goals.« less

  15. Induction of a G1-S checkpoint in fission yeast.

    PubMed

    Bøe, Cathrine A; Krohn, Marit; Rødland, Gro Elise; Capiaghi, Christoph; Maillard, Olivier; Thoma, Fritz; Boye, Erik; Grallert, Beáta

    2012-06-19

    Entry into S phase is carefully regulated and, in most organisms, under the control of a G(1)-S checkpoint. We have previously described a G(1)-S checkpoint in fission yeast that delays formation of the prereplicative complex at chromosomal replication origins after exposure to UV light (UVC). This checkpoint absolutely depends on the Gcn2 kinase. Here, we explore the signal for activation of the Gcn2-dependent G(1)-S checkpoint in fission yeast. If some form of DNA damage can activate the checkpoint, deficient DNA repair should affect the length of the checkpoint-induced delay. We find that the cell-cycle delay differs in repair-deficient mutants from that in wild-type cells. However, the duration of the delay depends not only on the repair capacity of the cells, but also on the nature of the repair deficiency. First, the delay is abolished in cells that are deficient in the early steps of repair. Second, the delay is prolonged in repair mutants that fail to complete repair after the incision stage. We conclude that the G(1)-S delay depends on damage to the DNA and that the activating signal derives not from the initial DNA damage, but from a repair intermediate(s). Surprisingly, we find that activation of Gcn2 does not depend on the processing of DNA damage and that activated Gcn2 alone is not sufficient to delay entry into S phase in UVC-irradiated cells. Thus, the G(1)-S delay depends on at least two different inputs.

  16. 75 FR 41922 - Notice of Intent To Rule on Request To Release Airport Property at Fort Smith Regional Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... To Release Airport Property at Fort Smith Regional Airport, Fort Smith, AR AGENCY: Federal Aviation... rule and invites public comment on the release of land at Fort Smith Regional Airport under the.... John Parker, Airport Director, Fort Smith Regional Airport, at the following address: Fort Smith...

  17. A Guidance Document on Airport Noise Control.

    DTIC Science & Technology

    1980-08-01

    airport . This Document is one of the tools designed to help airport operators and planners reach that goal. It should aid the reader in applying the...into the five major areas where airport noise control can be applied : airport plans, airport / airspace use, aircraft operation, land use, and noise...flights to another airport is just another form of rescheduling, though it need not apply only to night operations. The FAA is concerned about the

  18. 19 CFR 122.84 - Intermediate airport.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Intermediate airport. 122.84 Section 122.84... Intermediate airport. (a) Application. The provisions of this section apply at any U.S. airport to which an... aircraft arrives at the next airport, the aircraft commander or agent shall make entry by filing the: (1...

  19. 19 CFR 122.84 - Intermediate airport.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Intermediate airport. 122.84 Section 122.84... Intermediate airport. (a) Application. The provisions of this section apply at any U.S. airport to which an... aircraft arrives at the next airport, the aircraft commander or agent shall make entry by filing the: (1...

  20. 19 CFR 122.84 - Intermediate airport.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Intermediate airport. 122.84 Section 122.84... Intermediate airport. (a) Application. The provisions of this section apply at any U.S. airport to which an... aircraft arrives at the next airport, the aircraft commander or agent shall make entry by filing the: (1...

  1. 19 CFR 122.84 - Intermediate airport.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Intermediate airport. 122.84 Section 122.84... Intermediate airport. (a) Application. The provisions of this section apply at any U.S. airport to which an... aircraft arrives at the next airport, the aircraft commander or agent shall make entry by filing the: (1...

  2. 19 CFR 122.84 - Intermediate airport.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Intermediate airport. 122.84 Section 122.84... Intermediate airport. (a) Application. The provisions of this section apply at any U.S. airport to which an... aircraft arrives at the next airport, the aircraft commander or agent shall make entry by filing the: (1...

  3. Airport Performance and Construction Enlargement Activities

    NASA Astrophysics Data System (ADS)

    Hanun, Y.; Setiawan, M. I.; Kurniasih, N.; Hasyim, C.; Ahmar, A. S.

    2018-01-01

    The evaluation of transportation infrastructure project should consider the contribution towards infrastructure growth. This research aims to analyze the effect of Construction enlargement activities towards airport performance. This research is correlation study. The population includes 148 airports in Indonesia. By using total sampling, there were 148 sample airports. The result shows that the construction enlargement activities variable has relatively strong relationship to Airport Performance variable, while the adjusted R Square score shows the increasing construction enlargement activities that affected by the other factors aside from airport performance.

  4. 77 FR 44515 - Airport Improvement Program (AIP): Policy Regarding Access to Airports From Residential Property

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ... Committees. Going forward, the FAA expects sponsors of general aviation airports proposing to establish new... defined in the statute. However going forward, the FAA will apply the statutory prohibition on privately... activity onto the airport when feasible and practicable to do so. Going forward, airport sponsors proposing...

  5. 76 FR 18622 - Notice of Intent To Rule on Request To Release Airport Property at the Helena Regional Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    .... Ronald Mercer, Airport Director, Helena Regional Airport Authority (HRAA), at the following address: Mr. Ronald Mercer, Airport Director, Helena Regional Airport Authority, 2850 Skyway Drive, Helena, Montana...

  6. 14 CFR 125.49 - Airport requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Airport requirements. 125.49 Section 125.49... Requirements § 125.49 Airport requirements. (a) No certificate holder may use any airport unless it is adequate...) No pilot of an airplane carrying passengers at night may take off from, or land on, an airport unless...

  7. 14 CFR 125.49 - Airport requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Airport requirements. 125.49 Section 125.49... Requirements § 125.49 Airport requirements. (a) No certificate holder may use any airport unless it is adequate...) No pilot of an airplane carrying passengers at night may take off from, or land on, an airport unless...

  8. 14 CFR 125.49 - Airport requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Airport requirements. 125.49 Section 125.49... Requirements § 125.49 Airport requirements. (a) No certificate holder may use any airport unless it is adequate...) No pilot of an airplane carrying passengers at night may take off from, or land on, an airport unless...

  9. Airport Revenues: Galveston Municipal Airport; Scholes Field; Galveston, Texas; Federal Aviation Administration

    DOT National Transportation Integrated Search

    1997-11-07

    Our audit objectives were to determine whether (i) the city of Galveston, Texas : (city), was in compliance with its Airport Improvement Program grant assurances : and (ii) airport-generated revenues were used for the operating and capital cost : of ...

  10. To amend title 49, United States Code, to direct the Assistant Secretary of Homeland Security (Transportation Security Administration) to transfer unclaimed money recovered at airport security checkpoints to United Service Organizations, Incorporated, and for other purposes.

    THOMAS, 111th Congress

    Rep. Miller, Jeff [R-FL-1

    2009-04-30

    House - 05/26/2009 Referred to the Subcommittee on Transportation Security and Infrastructure Protection. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  11. 14 CFR 152.109 - Project eligibility: Airport planning.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Project eligibility: Airport planning. 152... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.109 Project eligibility: Airport planning. (a) Airport master planning. A proposed project for airport...

  12. 14 CFR 152.109 - Project eligibility: Airport planning.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Project eligibility: Airport planning. 152... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.109 Project eligibility: Airport planning. (a) Airport master planning. A proposed project for airport...

  13. 14 CFR 152.109 - Project eligibility: Airport planning.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Project eligibility: Airport planning. 152... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.109 Project eligibility: Airport planning. (a) Airport master planning. A proposed project for airport...

  14. 14 CFR 152.109 - Project eligibility: Airport planning.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Project eligibility: Airport planning. 152... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.109 Project eligibility: Airport planning. (a) Airport master planning. A proposed project for airport...

  15. Economic utilization of general aviation airport runways

    NASA Technical Reports Server (NTRS)

    Piper, R. R.

    1971-01-01

    The urban general aviation airport economics is studied in detail. The demand for airport services is discussed, and the different types of users are identified. The direct cost characteristics of the airport are summarized; costs to the airport owner are largely fixed, and, except at certain large airports, weight is not a significant factor in airport costs. The efficient use of an existing airport facility is explored, with the focus on the social cost of runway congestion as traffic density at the airport build up and queues form. The tradeoff between aircraft operating costs and airport costs is analyzed in terms of runway length. The transition from theory to practice is treated, and the policy of charging prices only on aircraft storage and fuel is felt likely to continue. Implications of the study from the standpoint of public policy include pricing that spreads traffic peaks to improve runway utilization, and pricing that discriminates against aircraft requiring long runways and causes owners to adopt V/STOL equipment.

  16. 78 FR 42419 - Airport Improvement Program (AIP): Policy Regarding Access to Airports From Residential Property

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-16

    ... assurances. In addition, Grant Assurance 29, Airport Layout Plan, was amended to require all proposed and... airport layout plan (ALP). A complete list of the current grant assurances can be viewed at: http://www... 29, Airport Layout Plan, should remain permissive; Using safety as a triggering event for a sponsor...

  17. Through-barrier detection of explosive components for security screening applications

    NASA Astrophysics Data System (ADS)

    Lee, Linda; Frisby, Alex; Mansson, Ralph; Hopkins, Rebecca J.

    2011-11-01

    The detection of materials through containers is a vital capability for security screening applications at high risk locations, such as airports and checkpoints. Current detection procedures require suspect containers to be opened and the contents sampled, which is laborious and potentially hazardous to the operator. The capability to detect through-barrier would overcome these issues. Spatially Offset Raman Spectroscopy (SORS) is an innovative spectroscopic technique that avoids fluorescence and Raman scatter from containers, which can mask the Raman signature from the sample. This novel approach enables noninvasive detection of hazardous and benign materials through a wider range of container materials than is possible using conventional Raman spectroscopy. SORS spectra were acquired from explosive compounds and benign materials within a range of coloured glass and plastic containers. The SORS spectra were compared to the reference Raman signatures of the materials studied. Two data analysis methods were then applied to the resultant data to investigate the ability of SORS to detect the target materials through the barriers tested. Furthermore, the potential for reduction of sample fluorescence was investigated by using longer excitation wavelength (1064 nm) than is typically used in commercially available Raman instruments that use silicon detector technology. For some fluorescent samples, Raman spectral features that were masked by fluorescence at 785 nm were revealed at 1064 nm.

  18. 41 CFR 102-75.400 - Is industrial property located on an airport also considered to be “airport property”?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Is industrial property located on an airport also considered to be âairport propertyâ? 102-75.400 Section 102-75.400 Public... Public Airports § 102-75.400 Is industrial property located on an airport also considered to be “airport...

  19. 41 CFR 102-75.400 - Is industrial property located on an airport also considered to be “airport property”?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Is industrial property located on an airport also considered to be âairport propertyâ? 102-75.400 Section 102-75.400 Public... Public Airports § 102-75.400 Is industrial property located on an airport also considered to be “airport...

  20. 41 CFR 102-75.400 - Is industrial property located on an airport also considered to be “airport property”?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Is industrial property located on an airport also considered to be âairport propertyâ? 102-75.400 Section 102-75.400 Public... Public Airports § 102-75.400 Is industrial property located on an airport also considered to be “airport...

  1. 41 CFR 102-75.400 - Is industrial property located on an airport also considered to be “airport property”?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Is industrial property located on an airport also considered to be âairport propertyâ? 102-75.400 Section 102-75.400 Public... Public Airports § 102-75.400 Is industrial property located on an airport also considered to be “airport...

  2. 41 CFR 102-75.400 - Is industrial property located on an airport also considered to be “airport property”?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Is industrial property located on an airport also considered to be âairport propertyâ? 102-75.400 Section 102-75.400 Public... Public Airports § 102-75.400 Is industrial property located on an airport also considered to be “airport...

  3. Replication licensing and the DNA damage checkpoint

    PubMed Central

    Cook, Jeanette Gowen

    2011-01-01

    Accurate and timely duplication of chromosomal DNA requires that replication be coordinated with processes that ensure genome integrity. Significant advances in determining how the earliest steps in DNA replication are affected by DNA damage have highlighted some of the mechanisms to establish that coordination. Recent insights have expanded the relationship between the ATM and ATR-dependent checkpoint pathways and the proteins that bind and function at replication origins. These findings suggest that checkpoints and replication are more intimately associated than previously appreciated, even in the absence of exogenous DNA damage. This review summarizes some of these developments. PMID:19482602

  4. A smart checkpointing scheme for improving the reliability of clustering routing protocols.

    PubMed

    Min, Hong; Jung, Jinman; Kim, Bongjae; Cho, Yookun; Heo, Junyoung; Yi, Sangho; Hong, Jiman

    2010-01-01

    In wireless sensor networks, system architectures and applications are designed to consider both resource constraints and scalability, because such networks are composed of numerous sensor nodes with various sensors and actuators, small memories, low-power microprocessors, radio modules, and batteries. Clustering routing protocols based on data aggregation schemes aimed at minimizing packet numbers have been proposed to meet these requirements. In clustering routing protocols, the cluster head plays an important role. The cluster head collects data from its member nodes and aggregates the collected data. To improve reliability and reduce recovery latency, we propose a checkpointing scheme for the cluster head. In the proposed scheme, backup nodes monitor and checkpoint the current state of the cluster head periodically. We also derive the checkpointing interval that maximizes reliability while using the same amount of energy consumed by clustering routing protocols that operate without checkpointing. Experimental comparisons with existing non-checkpointing schemes show that our scheme reduces both energy consumption and recovery latency.

  5. Analyzing checkpointing trends for applications on the IBM Blue Gene/P system.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Naik, H.; Gupta, R.; Beckman, P.

    Current petascale systems have tens of thousands of hardware components and complex system software stacks, which increase the probability of faults occurring during the lifetime of a process. Checkpointing has been a popular method of providing fault tolerance in high-end systems. While considerable research has been done to optimize checkpointing, in practice the method still involves a high-cost overhead for users. In this paper, we study the checkpointing overhead seen by applications running on leadership-class machines such as the IBM Blue Gene/P at Argonne National Laboratory. We study various applications and design a methodology to assist users in understanding andmore » choosing checkpointing frequency and reducing the overhead incurred. In particular, we study three popular applications -- the Grid-Based Projector-Augmented Wave application, the Carr-Parrinello Molecular Dynamics application, and a Nek5000 computational fluid dynamics application -- and analyze their memory usage and possible checkpointing trends on 32,768 processors of the Blue Gene/P system.« less

  6. A Smart Checkpointing Scheme for Improving the Reliability of Clustering Routing Protocols

    PubMed Central

    Min, Hong; Jung, Jinman; Kim, Bongjae; Cho, Yookun; Heo, Junyoung; Yi, Sangho; Hong, Jiman

    2010-01-01

    In wireless sensor networks, system architectures and applications are designed to consider both resource constraints and scalability, because such networks are composed of numerous sensor nodes with various sensors and actuators, small memories, low-power microprocessors, radio modules, and batteries. Clustering routing protocols based on data aggregation schemes aimed at minimizing packet numbers have been proposed to meet these requirements. In clustering routing protocols, the cluster head plays an important role. The cluster head collects data from its member nodes and aggregates the collected data. To improve reliability and reduce recovery latency, we propose a checkpointing scheme for the cluster head. In the proposed scheme, backup nodes monitor and checkpoint the current state of the cluster head periodically. We also derive the checkpointing interval that maximizes reliability while using the same amount of energy consumed by clustering routing protocols that operate without checkpointing. Experimental comparisons with existing non-checkpointing schemes show that our scheme reduces both energy consumption and recovery latency. PMID:22163389

  7. Operational Safety on Airports During Construction

    DOT National Transportation Integrated Search

    1984-05-31

    This advisory circular (AC) sets forth guidelines concerning the operational : safety on airports during construction, to assist airport operators in complying : with Part 139, Certification and Operation: Land Airports Serving Certain Air : Carriers...

  8. Airport Ground Access Planning Guide.

    DTIC Science & Technology

    1980-07-01

    30,000 daily passengers. On the other hand, express train/bus service to New York’s JFK Airport averaged about 1,000 passengers/ day in its first five...expected to depart New York’s JFK Airport during a peak ground traffic hour, and most of these vehicles are occupied by airport- based employees. It has

  9. Security : breaches at federal agencies and airports

    DOT National Transportation Integrated Search

    2000-01-01

    This is the statement of Robert H. Hast, Assistance Comptroller General for Investigations, Office of Special Investigations before the Subcommittee on Crime, House Committee on the Judiciary about potential security risks to the United States. The G...

  10. Airport capacity enhancement plan

    DOT National Transportation Integrated Search

    1986-01-01

    The first edition of the Airport Capacity Enhancement Plan has been developed : by the Federal Aviation Administration's newly established Airport Capacity Program : Office (ACPO). The plan is intended to increase the capacity and efficient utiliza :...

  11. Airport Capacity Enhancement Plan.

    DOT National Transportation Integrated Search

    1986-01-01

    The first edition of the Airport Capacity Enhancement Plan has been developed by the Federal Aviation Administration's newly established Airport Capacity Program Office (ACPO). The plan is intended to increase the capacity and efficient utilization o...

  12. Airport Capacity Enhancement Plan

    DOT National Transportation Integrated Search

    1987-01-01

    The first edition of the Airport Capacity Enhancement Plan has been developed by the Federal Aviation Administration's newly established Airport Capacity Program Office (ACPO). The plan is intended to increase the capacity and efficient utilization o...

  13. Tumor cell-associated immune checkpoint molecules - Drivers of malignancy and stemness.

    PubMed

    Marcucci, Fabrizio; Rumio, Cristiano; Corti, Angelo

    2017-12-01

    Inhibitory or stimulatory immune checkpoint molecules are expressed on a sizeable fraction of tumor cells in different tumor types. It was thought that the main function of tumor cell-associated immune checkpoint molecules would be the modulation (down- or upregulation) of antitumor immune responses. In recent years, however, it has become clear that the expression of immune checkpoint molecules on tumor cells has important consequences on the biology of the tumor cells themselves. In particular, a causal relationship between the expression of these molecules and the acquisition of malignant traits has been demonstrated. Thus, immune checkpoint molecules have been shown to promote the epithelial-mesenchymal transition of tumor cells, the acquisition of tumor-initiating potential and resistance to apoptosis and antitumor drugs, as well as the propensity to disseminate and metastasize. Herein, we review this evidence, with a main focus on PD-L1, the most intensively investigated tumor cell-associated immune checkpoint molecule and for which most information is available. Then, we discuss more concisely other tumor cell-associated immune checkpoint molecules that have also been shown to induce the acquisition of malignant traits, such as PD-1, B7-H3, B7-H4, Tim-3, CD70, CD28, CD137, CD40 and CD47. Open questions in this field as well as some therapeutic approaches that can be derived from this knowledge, are also addressed. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Checkpoint inhibitors in advanced melanoma: effect on the field of immunotherapy.

    PubMed

    O'reilly, Aine; Larkin, James

    2017-07-01

    The success of the immune checkpoint inhibitors in melanoma has reinvigorated the field of immunotherapy. Immune checkpoint inhibitors are now the standard of care in multiple cancer types including lung cancer, head and neck cancer, urothelial cancer and renal cell cancer. The field of immunotherapy is currently expanding rapidly and will be a focus of research and development for decades to come. Areas covered: This review covers the early development of immune checkpoint inhibitors and the changes that occurred in the drug development paradigm to facilitate the development of immunotherapy. The review will summarise the areas into which immune checkpoint inhibitors have been adopted and will review the data that supported this. Furthermore, we will discuss future developments in immunotherapy and the current landscape regarding maximising the potential of immunotherapy in clinical practice. Expert commentary: In the author's opinion, the potential of immunotherapy is vast. To date immune checkpoint inhibition has already delivered durable responses in a proportion of patients with cancer types which were previously universally lethal. The future of immunotherapy will rely upon the intelligent application of translational research to clinical practice, such that immunotherapy can be effective for a wider population and maintain its current growth.

  15. Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways

    PubMed Central

    Rhind, Nicholas; Russell, Paul

    2010-01-01

    SUMMARY Recent work on the mechanisms of DNA damage and replication cell cycle checkpoints has revealed great similarity between the checkpoint pathways of organisms as diverse as yeasts, flies and humans. However, there are differences in the ways these organisms regulate their cell cycles. To connect the conserved checkpoint pathways with various cell cycle targets requires an adaptable link that can target different cell cycle components in different organisms. The Chk1 and Cds1 protein kinases, downstream effectors in the checkpoint pathways, seem to play just such roles. Perhaps more surprisingly, the two kinases not only have different targets in different organisms but also seem to respond to different signals in different organisms. So, whereas in fission yeast Chk1 is required for the DNA damage checkpoint and Cds1 is specifically involved in the replication checkpoint, their roles seem to be shuffled in metazoans. PMID:11058076

  16. 49 CFR 37.33 - Airport transportation systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... systems operated by public airport operators, which provide designated public transportation and connect.... Public airports which operate fixed route transportation systems are subject to the requirements of this... part. (b) Fixed-route transportation systems operated by public airport operators between the airport...

  17. Gerardo Hernandez Airport Security Act of 2014

    THOMAS, 113th Congress

    Rep. Hudson, Richard [R-NC-8

    2014-06-05

    Senate - 07/23/2014 Received in the Senate and Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  18. 76 FR 70532 - Release of Airport Property: Melbourne International Airport, Melbourne, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ... Melbourne Airport Authority to dispose of the property for other than aeronautical purposes. The property is... Drive in Brevard County, Florida. This parcel is adjacent to airport property and is currently vacant...-aeronautical purposes. DATES: Comments are due on or before December 14, 2011. ADDRESSES: Documents are...

  19. 77 FR 12906 - Notice of Intent To Rule on Request To Release Airport Property at the Dubois Regional Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... To Release Airport Property at the Dubois Regional Airport, Reynoldsville, PA AGENCY: Federal Aviation Administration (FAA) DOT. ACTION: Notice of request to release airport property. SUMMARY: The FAA... Airport, Reynoldsville, Pennsylvania under the provisions of Section 47125(a) of Title 49 United States...

  20. Defective Cell Cycle Checkpoint Functions in Melanoma Are Associated with Altered Patterns of Gene Expression

    PubMed Central

    Kaufmann, William K.; Nevis, Kathleen R.; Qu, Pingping; Ibrahim, Joseph G.; Zhou, Tong; Zhou, Yingchun; Simpson, Dennis A.; Helms-Deaton, Jennifer; Cordeiro-Stone, Marila; Moore, Dominic T.; Thomas, Nancy E.; Hao, Honglin; Liu, Zhi; Shields, Janiel M.; Scott, Glynis A.; Sharpless, Norman E.

    2009-01-01

    Defects in DNA damage responses may underlie genetic instability and malignant progression in melanoma. Cultures of normal human melanocytes (NHMs) and melanoma lines were analyzed to determine whether global patterns of gene expression could predict the efficacy of DNA damage cell cycle checkpoints that arrest growth and suppress genetic instability. NHMs displayed effective G1 and G2 checkpoint responses to ionizing radiation-induced DNA damage. A majority of melanoma cell lines (11/16) displayed significant quantitative defects in one or both checkpoints. Melanomas with B-RAF mutations as a class displayed a significant defect in DNA damage G2 checkpoint function. In contrast the epithelial-like subtype of melanomas with wild-type N-RAS and B-RAF alleles displayed an effective G2 checkpoint but a significant defect in G1 checkpoint function. RNA expression profiling revealed that melanoma lines with defects in the DNA damage G1 checkpoint displayed reduced expression of p53 transcriptional targets, such as CDKN1A and DDB2, and enhanced expression of proliferation-associated genes, such as CDC7 and GEMININ. A Bayesian analysis tool was more accurate than significance analysis of microarrays for predicting checkpoint function using a leave-one-out method. The results suggest that defects in DNA damage checkpoints may be recognized in melanomas through analysis of gene expression. PMID:17597816

  1. Phase I AGTC Survey Airport Interviews

    DOT National Transportation Integrated Search

    1972-09-01

    This report presents the results of interviews conducted with airport management and FAA tower personnel during a survey of nine U.S. airports. This survey was conducted in December 1971 and January 1972 as part of a nationwide Airport Ground Traffic...

  2. Missouri airport investment study

    DOT National Transportation Integrated Search

    The studys purpose is to provide MoDOT with insight to the potential ROI for airport : investments in terms of economic development. To do so, this study addresses two central : objectives: first, an approach to evaluate airport investments; and s...

  3. The Airport Performance Model

    DOT National Transportation Integrated Search

    1976-04-01

    This report describes the development of a model and companion data base for evaluating levels and qualities of service provided to the public by Air Carrier Airports. The model is designed to translate changes in airport capabilities into public ser...

  4. Asynchronous Two-Level Checkpointing Scheme for Large-Scale Adjoints in the Spectral-Element Solver Nek5000

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schanen, Michel; Marin, Oana; Zhang, Hong

    Adjoints are an important computational tool for large-scale sensitivity evaluation, uncertainty quantification, and derivative-based optimization. An essential component of their performance is the storage/recomputation balance in which efficient checkpointing methods play a key role. We introduce a novel asynchronous two-level adjoint checkpointing scheme for multistep numerical time discretizations targeted at large-scale numerical simulations. The checkpointing scheme combines bandwidth-limited disk checkpointing and binomial memory checkpointing. Based on assumptions about the target petascale systems, which we later demonstrate to be realistic on the IBM Blue Gene/Q system Mira, we create a model of the expected performance of our checkpointing approach and validatemore » it using the highly scalable Navier-Stokes spectralelement solver Nek5000 on small to moderate subsystems of the Mira supercomputer. In turn, this allows us to predict optimal algorithmic choices when using all of Mira. We also demonstrate that two-level checkpointing is significantly superior to single-level checkpointing when adjoining a large number of time integration steps. To our knowledge, this is the first time two-level checkpointing had been designed, implemented, tuned, and demonstrated on fluid dynamics codes at large scale of 50k+ cores.« less

  5. 76 FR 30422 - Notice of Intent To Rule on Request To Release Airport Property at the Helena Regional Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... To Release Airport Property at the Helena Regional Airport, Helena, Montana AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Notice of Request to Release Airport Property... Airport (HLN) under the provisions of Section 125 of the Wendell H. Ford Aviation Investment Reform Act...

  6. 76 FR 23854 - Notice of Intent To Rule on Request To Release Airport Property at the Dubois Regional Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-28

    ... To Release Airport Property at the Dubois Regional Airport, Reynoldsville, PA AGENCY: Federal Aviation Administration (FAA) DOT. ACTION: Notice of request to release airport property. SUMMARY: The FAA proposes to rule and invite public comment on the release of land at the Dubois Regional Airport...

  7. Optimal message log reclamation for independent checkpointing

    NASA Technical Reports Server (NTRS)

    Wang, Yi-Min; Fuchs, W. Kent

    1993-01-01

    Independent (uncoordinated) check pointing for parallel and distributed systems allows maximum process autonomy but suffers from possible domino effects and the associated storage space overhead for maintaining multiple checkpoints and message logs. In most research on check pointing and recovery, it was assumed that only the checkpoints and message logs older than the global recovery line can be discarded. It is shown how recovery line transformation and decomposition can be applied to the problem of efficiently identifying all discardable message logs, thereby achieving optimal garbage collection. Communication trace-driven simulation for several parallel programs is used to show the benefits of the proposed algorithm for message log reclamation.

  8. Airport manager's guide for the maintenance of asphalt pavements of general aviation airports.

    DOT National Transportation Integrated Search

    2009-01-01

    Hot asphalt pavement (HAP) is used as a surface material on many General Aviation : (GA) airports in California. Currently there are 251 public use airports in California. An : understanding of the proper design, construction and maintenance of the h...

  9. Teaching Ideas Notebook: Student Airport Tours

    ERIC Educational Resources Information Center

    Journal of Aerospace Education, 1977

    1977-01-01

    Outlines, as recommended by the Aviation Distributors and Manufacturers Association, a cooperative program between schools and local airports. The Student Airport Tours Program for class and career study groups includes a field trip to an airport, free rides, and follow-up activities. (CS)

  10. 78 FR 20168 - Notice of Intent To Rule on Request To Release Airport Property at the Boulder Municipal Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-03

    ... To Release Airport Property at the Boulder Municipal Airport, Boulder, CO AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of request to release airport property. SUMMARY: The FAA proposes to rule and invite public comment on the release of land at Boulder Municipal Airport under the provisions...

  11. Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM

    PubMed Central

    Bower, Jacquelyn J.; Zhou, Yingchun; Zhou, Tong; Simpson, Dennis A.; Arlander, Sonnet J.; Paules, Richard S.; Cordeiro-Stone, Marila; Kaufmann, William K.

    2010-01-01

    The decatenation G2 checkpoint is proposed to delay cellular progression from G2 into mitosis when intertwined daughter chromatids are insufficiently decatenated. Previous studies indicated that the ATM- and Rad3-related (ATR) checkpoint kinase, but not the ataxia telangiectasia-mutated (ATM) kinase, was required for decatenation G2 checkpoint function. Here, we show that the method used to quantify decatenation G2 checkpoint function can influence the identification of genetic requirements for the checkpoint. Normal human diploid fibroblast (NHDF) lines responded to the topoisomerase II (topo II) catalytic inhibitor ICRF-193 with a stringent G2 arrest and a reduction in the mitotic index. While siRNA-mediated depletion of ATR and CHEK1 increased the mitotic index in ICRF-193 treated NHDF lines, depletion of these proteins did not affect the mitotic entry rate, indicating that the decatenation G2 checkpoint was functional. These results suggest that ATR and CHEK1 are not required for the decatenation G2 checkpoint, but may influence mitotic exit after inhibition of topo II. A re-evaluation of ataxia telangiectasia (AT) cell lines using the mitotic entry assay indicated that ATM was required for the decatenation G2 checkpoint. Three NHDF cell lines responded to ICRF-193 with a mean 98% inhibition of the mitotic entry rate. Examination of the mitotic entry rates in AT fibroblasts upon treatment with ICRF-193 revealed a significantly attenuated decatenation G2 checkpoint response, with a mean 59% inhibition of the mitotic entry rate. In addition, a normal lymphoblastoid line exhibited a 95% inhibition of the mitotic entry rate after incubation with ICRF-193, whereas two AT lymphoblastoid lines displayed only 36% and 20% inhibition of the mitotic entry rate. Stable depletion of ATM in normal human fibroblasts with short hairpin RNA also attenuated decatenation G2 checkpoint function by an average of 40%. Western immunoblot analysis demonstrated that treatment with ICRF

  12. Homeland Security Department: FY2009 Appropriations

    DTIC Science & Technology

    2009-03-04

    security fees 2,113 2,329 TWIC 64 9 Hazmat 18 18 TSA Registered Traveler 4 10 FEMA/EPR National Flood Insurance Fund 111 157 CBP Small airports 7...Border. f. Fees include TWIC, HAZMAT, Registered Traveler , and Alien Flight School Checks. Homeland Security Department: FY2009 Appropriations CRS...unauthorized travelers and immigrants; and enforcing more than 400 laws and regulations at the border on behalf of more than 60 government agencies

  13. The pachytene checkpoint and its relationship to evolutionary patterns of polyploidization and hybrid sterility.

    PubMed

    Li, X C; Barringer, B C; Barbash, D A

    2009-01-01

    Sterility is a commonly observed phenotype in interspecific hybrids. Sterility may result from chromosomal or genic incompatibilities, and much progress has been made toward understanding the genetic basis of hybrid sterility in various taxa. The underlying mechanisms causing hybrid sterility, however, are less well known. The pachytene checkpoint is a meiotic surveillance system that many organisms use to detect aberrant meiotic products, in order to prevent the production of defective gametes. We suggest that activation of the pachytene checkpoint may be an important mechanism contributing to two types of hybrid sterility. First, the pachytene checkpoint may form the mechanistic basis of some gene-based hybrid sterility phenotypes. Second, the pachytene checkpoint may be an important mechanism that mediates chromosomal-based hybrid sterility phenotypes involving gametes with non-haploid (either non-reduced or aneuploid) chromosome sets. Studies in several species suggest that the strength of the pachytene checkpoint is sexually dimorphic, observations that warrant future investigation into whether such variation may contribute to differences in patterns of sterility between male and female interspecific hybrids. In addition, plants seem to lack the pachytene checkpoint, which correlates with increased production of unreduced gametes and a higher incidence of polyploid species in plants versus animals. Although the pachytene checkpoint occurs in many animals and in fungi, at least some of the genes that execute the pachytene checkpoint are different among organisms. This finding suggests that the penetrance of the pachytene checkpoint, and even its presence or absence can evolve rapidly. The surprising degree of evolutionary flexibility in this meiotic surveillance system may contribute to the observed variation in patterns of hybrid sterility and in rates of polyploidization.

  14. mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development

    PubMed Central

    Brodsky, Michael H.; Sekelsky, Jeff J.; Tsang, Garson; Hawley, R. Scott; Rubin, Gerald M.

    2000-01-01

    Checkpoints block cell cycle progression in eukaryotic cells exposed to DNA damaging agents. We show that several Drosophila homologs of checkpoint genes, mei-41, grapes, and 14-3-3ε, regulate a DNA damage checkpoint in the developing eye. We have used this assay to show that the mutagen-sensitive gene mus304 is also required for this checkpoint. mus304 encodes a novel coiled-coil domain protein, which is targeted to the cytoplasm. Similar to mei-41, mus304 is required for chromosome break repair and for genomic stability. mus304 animals also exhibit three developmental defects, abnormal bristle morphology, decreased meiotic recombination, and arrested embryonic development. We suggest that these phenotypes reflect distinct developmental consequences of a single underlying checkpoint defect. Similar mechanisms may account for the puzzling array of symptoms observed in humans with mutations in the ATM tumor suppressor gene. PMID:10733527

  15. Airport noise impact reduction through operations

    NASA Technical Reports Server (NTRS)

    Deloach, R.

    1981-01-01

    The airport-noise levels and annoyance model (ALAMO) developed at NASA Langley Research Center is comprised of a system of computer programs which is capable of quantifying airport community noise impact in terms of noise level, population distribution, and human subjective response to noise. The ALAMO can be used to compare the noise impact of an airport's current operating scenario with the noise impact which would result from some proposed change in airport operations. The relative effectiveness of number of noise-impact reduction alternatives is assessed for a major midwest airport. Significant reductions in noise impact are predicted for certain noise abatement strategies while others are shown to result in relatively little noise relief.

  16. Next generation of immune checkpoint therapy in cancer: new developments and challenges.

    PubMed

    Marin-Acevedo, Julian A; Dholaria, Bhagirathbhai; Soyano, Aixa E; Knutson, Keith L; Chumsri, Saranya; Lou, Yanyan

    2018-03-15

    Immune checkpoints consist of inhibitory and stimulatory pathways that maintain self-tolerance and assist with immune response. In cancer, immune checkpoint pathways are often activated to inhibit the nascent anti-tumor immune response. Immune checkpoint therapies act by blocking or stimulating these pathways and enhance the body's immunological activity against tumors. Cytotoxic T lymphocyte-associated molecule-4 (CTLA-4), programmed cell death receptor-1 (PD-1), and programmed cell death ligand-1(PD-L1) are the most widely studied and recognized inhibitory checkpoint pathways. Drugs blocking these pathways are currently utilized for a wide variety of malignancies and have demonstrated durable clinical activities in a subset of cancer patients. This approach is rapidly extending beyond CTLA-4 and PD-1/PD-L1. New inhibitory pathways are under investigation, and drugs blocking LAG-3, TIM-3, TIGIT, VISTA, or B7/H3 are being investigated. Furthermore, agonists of stimulatory checkpoint pathways such as OX40, ICOS, GITR, 4-1BB, CD40, or molecules targeting tumor microenvironment components like IDO or TLR are under investigation. In this article, we have provided a comprehensive review of immune checkpoint pathways involved in cancer immunotherapy, and discuss their mechanisms and the therapeutic interventions currently under investigation in phase I/II clinical trials. We also reviewed the limitations, toxicities, and challenges and outline the possible future research directions.

  17. 19 CFR 122.14 - Landing rights airport.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Landing rights airport. 122.14 Section 122.14... TREASURY AIR COMMERCE REGULATIONS Classes of Airports § 122.14 Landing rights airport. (a) Permission to land. Permission to land at a landing rights airport may be given as follows: (1) Scheduled flight. The...

  18. 19 CFR 122.14 - Landing rights airport.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Landing rights airport. 122.14 Section 122.14... TREASURY AIR COMMERCE REGULATIONS Classes of Airports § 122.14 Landing rights airport. (a) Permission to land. Permission to land at a landing rights airport may be given as follows: (1) Scheduled flight. The...

  19. 19 CFR 122.14 - Landing rights airport.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Landing rights airport. 122.14 Section 122.14... TREASURY AIR COMMERCE REGULATIONS Classes of Airports § 122.14 Landing rights airport. (a) Permission to land. Permission to land at a landing rights airport may be given as follows: (1) Scheduled flight. The...

  20. 19 CFR 122.14 - Landing rights airport.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Landing rights airport. 122.14 Section 122.14... TREASURY AIR COMMERCE REGULATIONS Classes of Airports § 122.14 Landing rights airport. (a) Permission to land. Permission to land at a landing rights airport may be given as follows: (1) Scheduled flight. The...

  1. 19 CFR 122.14 - Landing rights airport.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Landing rights airport. 122.14 Section 122.14... TREASURY AIR COMMERCE REGULATIONS Classes of Airports § 122.14 Landing rights airport. (a) Permission to land. Permission to land at a landing rights airport may be given as follows: (1) Scheduled flight. The...

  2. Aviation security : terrorist acts demonstrate urgent need to improve security at the nation's airports

    DOT National Transportation Integrated Search

    2001-09-20

    A safe and secure civil aviation system is a critical component of the nation's overall security, physical infrastructure, and economic foundation. Billions of dollars and a myriad of programs and policies have been devoted to achieving such a system...

  3. [Airport related air pollution and health effects].

    PubMed

    Iavicoli, Ivo; Fontana, Luca; Ancona, Carla; Forastiere, Francesco

    2014-01-01

    Airport is an extremely complex emission source of airborne pollutants that can have a significant impact on the environment. Indeed, several airborne chemicals emitted during airport activities may significantly get worse air quality and increase exposure level of both airport workers and general population living nearby the airports. In recent years airport traffic has increased and consequently several studies investigated the association between airport-related air pollution and occurrence of adverse health effects, particularly on respiratory system, in exposed workers and general population resident nearby. In this context, we carried out a critical evaluation of the studies that investigated this correlation in order to obtain a deeper knowledge of this issue and to identify the future research needs. Results show that the evidence of association between airport-related air pollution and health effects on workers and residents is still limited.

  4. 14 CFR 139.205 - Amendment of Airport Certification Manual.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) Under § 139.3, the Regional Airports Division Manager may amend any Airport Certification Manual... Airports Division Manager's own initiative, if the Regional Airports Division Manager determines that... proposed amendment to its Airport Certification Manual to the Regional Airports Division Manager at least...

  5. Chromatin Remodeling Factors Isw2 and Ino80 Regulate Checkpoint Activity and Chromatin Structure in S Phase

    PubMed Central

    Lee, Laura; Rodriguez, Jairo; Tsukiyama, Toshio

    2015-01-01

    When cells undergo replication stress, proper checkpoint activation and deactivation are critical for genomic stability and cell survival and therefore must be highly regulated. Although mechanisms of checkpoint activation are well studied, mechanisms of checkpoint deactivation are far less understood. Previously, we reported that chromatin remodeling factors Isw2 and Ino80 attenuate the S-phase checkpoint activity in Saccharomyces cerevisiae, especially during recovery from hydroxyurea. In this study, we found that Isw2 and Ino80 have a more pronounced role in attenuating checkpoint activity during late S phase in the presence of methyl methanesulfonate (MMS). We therefore screened for checkpoint factors required for Isw2 and Ino80 checkpoint attenuation in the presence of MMS. Here we demonstrate that Isw2 and Ino80 antagonize checkpoint activators and attenuate checkpoint activity in S phase in MMS either through a currently unknown pathway or through RPA. Unexpectedly, we found that Isw2 and Ino80 increase chromatin accessibility around replicating regions in the presence of MMS through a novel mechanism. Furthermore, through growth assays, we provide additional evidence that Isw2 and Ino80 partially counteract checkpoint activators specifically in the presence of MMS. Based on these results, we propose that Isw2 and Ino80 attenuate S-phase checkpoint activity through a novel mechanism. PMID:25701287

  6. Synthetic aperture radar imagery of airports and surrounding areas: Philadelphia Airport

    NASA Technical Reports Server (NTRS)

    Onstott, Robert G.; Gineris, Denise J.

    1990-01-01

    The statistical description of ground clutter at an airport and in the surrounding area is addressed. These data are being utilized in a program to detect microbursts. Synthetic Aperture Radar (SAR) data were collected at the Philadelphia Airport. These data and the results of the clutter study are described. This 13 km x 10 km scene was imaged at 9.38 GHz and HH-polarization and contained airport grounds and facilities (6 percent), industrial (14 percent), residential (14 percent), fields (10 percent), forest (8 percent), and water (33 percent). Incidence angles ranged from 40 to 84 deg. Even at the smallest incidence angles, the distributed targets such as forest, fields, water, and residential rarely had mean scattering coefficients greater than -10 dB. Eighty-seven percent of the image had scattering coefficients less than -17.5 dB. About 1 percent of the scattering coefficients exceeded 0 dB, with about 0.1 percent above 10 dB. Sources which produced the largest cross sections were largely confined to the airport grounds and areas highly industrialized. The largest cross sections were produced by observing broadside large buildings surrounded by smooth surfaces.

  7. Understanding checkpointing overheads on massive-scale systems : analysis of the IBM Blue Gene/P system.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gupta, R.; Naik, H.; Beckman, P.

    Providing fault tolerance in high-end petascale systems, consisting of millions of hardware components and complex software stacks, is becoming an increasingly challenging task. Checkpointing continues to be the most prevalent technique for providing fault tolerance in such high-end systems. Considerable research has focussed on optimizing checkpointing; however, in practice, checkpointing still involves a high-cost overhead for users. In this paper, we study the checkpointing overhead seen by various applications running on leadership-class machines like the IBM Blue Gene/P at Argonne National Laboratory. In addition to studying popular applications, we design a methodology to help users understand and intelligently choose anmore » optimal checkpointing frequency to reduce the overall checkpointing overhead incurred. In particular, we study the Grid-Based Projector-Augmented Wave application, the Carr-Parrinello Molecular Dynamics application, the Nek5000 computational fluid dynamics application and the Parallel Ocean Program application-and analyze their memory usage and possible checkpointing trends on 65,536 processors of the Blue Gene/P system.« less

  8. The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.

    PubMed

    Matlung, Hanke L; Szilagyi, Katka; Barclay, Neil A; van den Berg, Timo K

    2017-03-01

    Immune checkpoint inhibitors, including those targeting CTLA-4/B7 and the PD-1/PD-L1 inhibitory pathways, are now available for clinical use in cancer patients, with other interesting checkpoint inhibitors being currently in development. Most of these have the purpose to promote adaptive T cell-mediated immunity against cancer. Here, we review another checkpoint acting to potentiate the activity of innate immune cells towards cancer. This innate immune checkpoint is composed of what has become known as the 'don't-eat me' signal CD47, which is a protein broadly expressed on normal cells and often overexpressed on cancer cells, and its counter-receptor, the myeloid inhibitory immunoreceptor SIRPα. Blocking CD47-SIRPα interactions has been shown to promote the destruction of cancer cells by phagocytes, including macrophages and neutrophils. Furthermore, there is growing evidence that targeting of the CD47-SIRPα axis may also promote antigen-presenting cell function and thereby stimulate adaptive T cell-mediated anti-cancer immunity. The development of CD47-SIRPα checkpoint inhibitors and the potential side effects that these may have are discussed. Collectively, this identifies the CD47-SIRPα axis as a promising innate immune checkpoint in cancer, and with data of the first clinical studies with CD47-SIRPα checkpoint inhibitors expected within the coming years, this is an exciting and rapidly developing field. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. Myasthenia triggered by immune checkpoint inhibitors: New case and literature review.

    PubMed

    Gonzalez, Natalia L; Puwanant, Araya; Lu, Angela; Marks, Stanley M; Živković, Saša A

    2017-03-01

    Immune checkpoint molecules are potent regulators of immunologic homeostasis that prevent the development of autoimmunity while maintaining self-tolerance. Inhibitors of immune checkpoint molecules are used as immunotherapy in the treatment of melanoma and different types of refractory cancer, and can trigger various autoimmune complications including myositis and myasthenia gravis. We describe a case of generalized myasthenia gravis induced by pembrolizumab and review 11 other cases. Five patients also had elevated serum CK levels ranging from 1200 to 8729 IU/L, and biopsy showed myositis in one. Severity was highly variable as symptoms normalized spontaneously in one patient, but three others developed myasthenic crisis (including two with fatal outcomes). Steroids have been recommended as a preferred treatment of autoimmune complications of immune-checkpoint inhibitors. Myasthenia gravis should be considered when weakness, diplopia or bulbar symptoms are seen after treatment with immune checkpoint inhibitors, and additional studies are needed to characterize association with hyperCKemia. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Expression of immune checkpoints in T cells of esophageal cancer patients.

    PubMed

    Xie, Jinhua; Wang, Ji; Cheng, Shouliang; Zheng, Liangfeng; Ji, Feiyue; Yang, Lin; Zhang, Yan; Ji, Haoming

    2016-09-27

    Inhibition of immune checkpoint proteins (checkpoints) has become a promising anti-esophageal cancer strategy. We here tested expressions of immune checkpoints in human esophageal cancers. Our results showed the expressions of many immune checkpoints, including CD28, CD27, CD137L, programmed death 1 (PD-1), T cell immunoglobulin mucin-3 (TIM-3), T cell Ig and ITIM domain (TIGIT), CD160, cytotoxic T lymphocyte antigen 4 (CTLA-4), CD200, CD137 and CD158, were dysregulated in peripheral T cells of esophageal cancer patients. Further, the expressions of PD-1, TIM-3 and TIGIT were upregulated in tumor infiltrating lymphocytes (TILs), which might be associated with TILs exhaustion. Meanwhile, the expressions of PD-1 and TIM-3 on CD4+ T cells were closely associated with clinic pathological features of esophageal cancer patients. These results indicate that co-inhibitory receptors PD-1, TIM-3 and TIGIT may be potential therapeutic oncotargets for esophageal cancer.

  11. 19 CFR 122.15 - User fee airports.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false User fee airports. 122.15 Section 122.15 Customs... AIR COMMERCE REGULATIONS Classes of Airports § 122.15 User fee airports. (a) Permission to land. The procedures for obtaining permission to land at a user fee airport are the same procedures as those set forth...

  12. 19 CFR 122.15 - User fee airports.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false User fee airports. 122.15 Section 122.15 Customs... AIR COMMERCE REGULATIONS Classes of Airports § 122.15 User fee airports. (a) Permission to land. The procedures for obtaining permission to land at a user fee airport are the same procedures as those set forth...

  13. 19 CFR 122.15 - User fee airports.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false User fee airports. 122.15 Section 122.15 Customs... AIR COMMERCE REGULATIONS Classes of Airports § 122.15 User fee airports. (a) Permission to land. The procedures for obtaining permission to land at a user fee airport are the same procedures as those set forth...

  14. 14 CFR 139.205 - Amendment of Airport Certification Manual.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Amendment of Airport Certification Manual... CERTIFICATION OF AIRPORTS Airport Certification Manual § 139.205 Amendment of Airport Certification Manual. (a) Under § 139.3, the Regional Airports Division Manager may amend any Airport Certification Manual...

  15. 14 CFR 139.205 - Amendment of Airport Certification Manual.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Amendment of Airport Certification Manual... CERTIFICATION OF AIRPORTS Airport Certification Manual § 139.205 Amendment of Airport Certification Manual. (a) Under § 139.3, the Regional Airports Division Manager may amend any Airport Certification Manual...

  16. 14 CFR 139.205 - Amendment of Airport Certification Manual.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Amendment of Airport Certification Manual... CERTIFICATION OF AIRPORTS Airport Certification Manual § 139.205 Amendment of Airport Certification Manual. (a) Under § 139.3, the Regional Airports Division Manager may amend any Airport Certification Manual...

  17. 14 CFR 139.205 - Amendment of Airport Certification Manual.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Amendment of Airport Certification Manual... CERTIFICATION OF AIRPORTS Airport Certification Manual § 139.205 Amendment of Airport Certification Manual. (a) Under § 139.3, the Regional Airports Division Manager may amend any Airport Certification Manual...

  18. 19 CFR 122.85 - Final airport.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Final airport. 122.85 Section 122.85 Customs... AIR COMMERCE REGULATIONS Procedures for Residue Cargo and Stopover Passengers § 122.85 Final airport. When an aircraft enters at the last domestic airport of discharge, the traveling general declaration...

  19. 19 CFR 122.85 - Final airport.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Final airport. 122.85 Section 122.85 Customs... AIR COMMERCE REGULATIONS Procedures for Residue Cargo and Stopover Passengers § 122.85 Final airport. When an aircraft enters at the last domestic airport of discharge, the traveling general declaration...

  20. 19 CFR 122.85 - Final airport.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Final airport. 122.85 Section 122.85 Customs... AIR COMMERCE REGULATIONS Procedures for Residue Cargo and Stopover Passengers § 122.85 Final airport. When an aircraft enters at the last domestic airport of discharge, the traveling general declaration...

  1. 19 CFR 122.85 - Final airport.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Final airport. 122.85 Section 122.85 Customs... AIR COMMERCE REGULATIONS Procedures for Residue Cargo and Stopover Passengers § 122.85 Final airport. When an aircraft enters at the last domestic airport of discharge, the traveling general declaration...

  2. 19 CFR 122.85 - Final airport.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Final airport. 122.85 Section 122.85 Customs... AIR COMMERCE REGULATIONS Procedures for Residue Cargo and Stopover Passengers § 122.85 Final airport. When an aircraft enters at the last domestic airport of discharge, the traveling general declaration...

  3. Siting Solar Photovoltaics at Airports: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kandt, A.; Romero, R.

    2014-06-01

    Airports present a significant opportunity for hosting solar technologies due to their open land; based on a 2010 Federal Aviation Administration study, the US Department of Agriculture, and the US Fish and Wildlife Service, there's potential for 116,704 MW of solar photovoltaics (PV) on idle lands at US airports. PV has a low profile and likely low to no impact on flight operations. This paper outlines guidance for implementing solar technologies at airports and airfields, focusing largely on the Federal Aviation Administration's policies. The paper also details best practices for siting solar at airports, provides information on the Solar Glaremore » Hazard Analysis Tool, and highlights a case study example where solar has been installed at an airport.« less

  4. Airport baggage handling--where do human factors fit in the challenges that airports put on a baggage system?

    PubMed

    Lenior, O N M

    2012-01-01

    The challenges put on large baggage systems by airports can be summarized as: handling a high number of bags in a short period of time, in a limited space, with all sorts of disruptions, whilst complying with stringent regulation upon security, sustainability and health and safety. The aim of this company case study is to show in the different project phases--as indicated in the system ergonomic approach--how the human factors specialist can play a major part in tackling these challenges. By describing different projects in terms of scope, organization, human factors topics covered, phases and lessons learned, the importance of Human-Computer Interaction, automation as well as manual handling and work organization in baggage is addressed.

  5. 49 CFR 27.71 - Airport facilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Airport facilities. 27.71 Section 27.71... Administration Programs: Airports, Railroads, and Highways § 27.71 Airport facilities. (a) This section applies to all terminal facilities and services owned, leased, or operated on any basis by a recipient of DOT...

  6. Airport landside operations and air service

    NASA Astrophysics Data System (ADS)

    Mandle, P. B.; Whitlock, E. M.; Lamagna, F.; Mundy, R. A.; Oberhausen, P. J.

    The following areas are discussed: airport curbside planning and design; analysis of New Orleans airport ground transportation system; time series analysis of intercity air travel volume; economic justification of air service to small communities; and general aviation and the airport and airway system (an analysis of cost allocation and recovery).

  7. 32 CFR 644.423 - Airport development.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Airport development. 644.423 Section 644.423... ESTATE HANDBOOK Disposal Disposal of Fee-Owned Real Property and Easement Interests § 644.423 Airport... carrying out a project for airport development under this subchapter, or for the operation of any public...

  8. 32 CFR 644.423 - Airport development.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Airport development. 644.423 Section 644.423... ESTATE HANDBOOK Disposal Disposal of Fee-Owned Real Property and Easement Interests § 644.423 Airport... carrying out a project for airport development under this subchapter, or for the operation of any public...

  9. 14 CFR 398.3 - Specific airports.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Specific airports. 398.3 Section 398.3... STATEMENTS GUIDELINES FOR INDIVIDUAL DETERMINATIONS OF BASIC ESSENTIAL AIR SERVICE § 398.3 Specific airports. (a) At an eligible place, essential air service may be specified as service to a particular airport...

  10. 14 CFR 398.3 - Specific airports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Specific airports. 398.3 Section 398.3... STATEMENTS GUIDELINES FOR INDIVIDUAL DETERMINATIONS OF BASIC ESSENTIAL AIR SERVICE § 398.3 Specific airports. (a) At an eligible place, essential air service may be specified as service to a particular airport...

  11. 32 CFR 644.423 - Airport development.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Airport development. 644.423 Section 644.423... ESTATE HANDBOOK Disposal Disposal of Fee-Owned Real Property and Easement Interests § 644.423 Airport... carrying out a project for airport development under this subchapter, or for the operation of any public...

  12. 14 CFR 398.3 - Specific airports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Specific airports. 398.3 Section 398.3... STATEMENTS GUIDELINES FOR INDIVIDUAL DETERMINATIONS OF BASIC ESSENTIAL AIR SERVICE § 398.3 Specific airports. (a) At an eligible place, essential air service may be specified as service to a particular airport...

  13. 14 CFR 398.3 - Specific airports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Specific airports. 398.3 Section 398.3... STATEMENTS GUIDELINES FOR INDIVIDUAL DETERMINATIONS OF BASIC ESSENTIAL AIR SERVICE § 398.3 Specific airports. (a) At an eligible place, essential air service may be specified as service to a particular airport...

  14. 14 CFR 398.3 - Specific airports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Specific airports. 398.3 Section 398.3... STATEMENTS GUIDELINES FOR INDIVIDUAL DETERMINATIONS OF BASIC ESSENTIAL AIR SERVICE § 398.3 Specific airports. (a) At an eligible place, essential air service may be specified as service to a particular airport...

  15. Development of Airport Noise Mapping using Matlab Software (Case Study: Adi Soemarmo Airport - Boyolali, Indonesia)

    NASA Astrophysics Data System (ADS)

    Andarani, Pertiwi; Setiyo Huboyo, Haryono; Setyanti, Diny; Budiawan, Wiwik

    2018-02-01

    Noise is considered as one of the main environmental impact of Adi Soemarmo International Airport (ASIA), the second largest airport in Central Java Province, Indonesia. In order to manage the noise of airport, airport noise mapping is necessary. However, a model that requires simple input but still reliable was not available in ASIA. Therefore, the objective of this study are to develop model using Matlab software, to verify its reliability by measuring actual noise exposure, and to analyze the area of noise levels‥ The model was developed based on interpolation or extrapolation of identified Noise-Power-Distance (NPD) data. In accordance with Indonesian Government Ordinance No.40/2012, the noise metric used is WECPNL (Weighted Equivalent Continuous Perceived Noise Level). Based on this model simulation, there are residence area in the region of noise level II (1.912 km2) and III (1.16 km2) and 18 school buildings in the area of noise levels I, II, and III. These land-uses are actually prohibited unless noise insulation is equipped. The model using Matlab in the case of Adi Soemarmo International Airport is valid based on comparison of the field measurement (6 sampling points). However, it is important to validate the model again once the case study (the airport) is changed.

  16. Airport Access/Egress Systems Study : Volume 1. Text.

    DOT National Transportation Integrated Search

    1973-09-01

    Studies of airport activities and user characteristics at 34 high volume U. S. airports indicate that disbursed trip origins cannot economically justify rapid transit corridor investments dedicated to airport access travel. Generally, airports have t...

  17. Open-area concealed-weapon detection system

    NASA Astrophysics Data System (ADS)

    Pati, P.; Mather, P.

    2011-06-01

    Concealed Weapon Detection (CWD) has become a significant challenge to present day security needs; individuals carrying weapons into airplanes, schools, and secured establishments are threat to public security. Although controlled screening, of people for concealed weapons, has been employed in many establishments, procedures and equipment are designed to work in restricted environments like airport passport control, military checkpoints, hospitals, school and university entrance. Furthermore, screening systems do not effectively decipher between threat and non-threat metal objects, thus leading to high rate of false alarms which can become a liability to daily operational needs of establishments. Therefore, the design and development of a new CWD system to operate in a large open area environment with large numbers of people reduced incidences of false alarms and increased location accuracy is essential.

  18. Pavement Technology and Airport Infrastructure Expansion Impact

    NASA Astrophysics Data System (ADS)

    Sabib; Setiawan, M. I.; Kurniasih, N.; Ahmar, A. S.; Hasyim, C.

    2018-01-01

    This research aims for analyzing construction and infrastructure development activities potential contribution towards Airport Performance. This research is correlation study with variable research that includes Airport Performance as X variable and construction and infrastructure development activities as Y variable. The population in this research is 148 airports in Indonesia. The sampling technique uses total sampling, which means 148 airports that becomes the population unit then all of it become samples. The results of coefficient correlation (R) test showed that construction and infrastructure development activities variable have a relatively strong relationship with Airport Performance variable, but the value of Adjusted R Square shows that an increase in the construction and infrastructure development activities is influenced by factor other than Airport Performance.

  19. Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis.

    PubMed

    Saurin, Adrian T; van der Waal, Maike S; Medema, René H; Lens, Susanne M A; Kops, Geert J P L

    2011-01-01

    The mitotic checkpoint prevents mitotic exit until all chromosomes are attached to spindle microtubules. Aurora B kinase indirectly invokes this checkpoint by destabilizing incorrect attachments; however, a more direct role remains controversial. In contrast, activity of the kinase Mps1 is indispensible for the mitotic checkpoint. Here we show that Aurora B and Hec1 are needed for efficient Mps1 recruitment to unattached kinetochores, allowing rapid Mps1 activation at the onset of mitosis. Live monitoring of cyclin B degradation reveals that this is essential to establish the mitotic checkpoint quickly at the start of mitosis. Delayed Mps1 activation and checkpoint establishment upon Aurora B inhibition or Hec1 depletion are rescued by tethering Mps1 to kinetochores, demonstrating that Mps1 recruitment is the primary role of Aurora B and Hec1 in mitotic checkpoint signalling. These data demonstrate a direct role for Aurora B in initiating the mitotic checkpoint rapidly at the onset of mitosis.

  20. Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint.

    PubMed

    London, Nitobe; Biggins, Sue

    2014-01-15

    The spindle checkpoint is a conserved signaling pathway that ensures genomic integrity by preventing cell division when chromosomes are not correctly attached to the spindle. Checkpoint activation depends on the hierarchical recruitment of checkpoint proteins to generate a catalytic platform at the kinetochore. Although Mad1 kinetochore localization is the key regulatory downstream event in this cascade, its receptor and mechanism of recruitment have not been conclusively identified. Here, we demonstrate that Mad1 kinetochore association in budding yeast is mediated by phosphorylation of a region within the Bub1 checkpoint protein by the conserved protein kinase Mps1. Tethering this region of Bub1 to kinetochores bypasses the checkpoint requirement for Mps1-mediated kinetochore recruitment of upstream checkpoint proteins. The Mad1 interaction with Bub1 and kinetochores can be reconstituted in the presence of Mps1 and Mad2. Together, this work reveals a critical mechanism that determines kinetochore activation of the spindle checkpoint.