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Sample records for al appl opt

  1. 78 FR 22298 - United States v. Apple, Inc., et al.; Public Comments and Response on Proposed Final Judgment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-15

    ... States v. Apple, Inc., et al., Civil Action No. 12-CV-2826 (DLC), which was filed in the United States.... Civil Action No. 12-CV-2826 (DLC) ECF Case Response by Plaintiff United States to Public Comments on...

  2. 78 FR 33437 - United States v. Apple, Inc., et al.; Public Comments and Response on Proposed Final Judgment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... Macmillan in United States v. Apple, Inc., et al., Civil Action No. 12-CV-2826 (DLC), which was filed in the...., Defendants. Civil Action No. 12-CV-2826 (DLC) ECF Case Response by Plaintiff United States to Public...

  3. 77 FR 44271 - United States v. Apple, Inc., et al.; Public Comments and Response on Proposed Final Judgment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Antitrust Division United States v. Apple, Inc., et al.; Public Comments and Response on Proposed Final Judgment Pursuant to the Antitrust Procedures and Penalties Act, 15 U.S.C. 16(b)-(h), the United States hereby publishes below the United...

  4. Consent in escrow: opting to opt in

    PubMed Central

    Van der Loos, Kiah I.; Longstaff, Holly; Virani, Alice; Illes, Judy

    2015-01-01

    In this paper, we reply to Taylor's (2015) peer commentary on consent-in-escrow. Specifically, we clarify the utility of this novel approach, the way in which it minimizes risks to participants, and how it differs from existing opt-out methods. We further explore its potential use in fields beyond disaster research. PMID:27774229

  5. Study of Row Phase Dependent Skew Quadrupole Fields in Apple-II Type EPUs at the ALS

    SciTech Connect

    Steier, C.; Marks, S.; Prestemon, Soren; Robin, David; Schlueter, Ross; Wolski, Andrzej

    2004-05-07

    Since about 5 years, Apple-II type Elliptically Polarizing Undulators (EPU) have been used very successfully at the ALS to generate high brightness photon beams with arbitrary polarization. However, both EPUs installed so far cause significant changes of the vertical beamsize, especially when the row phase is changed to change the polarization of the photons emitted. Detailed measurements indicate this is caused by a row phase dependent skew quadrupole term in the EPUs. Magnetic measurements revealed the same effect for the third EPU to be installed later this year. All measurements to identify and quantify the effect with beam will be presented, as well as some results of magnetic bench measurements and numeric field simulations.

  6. 12 CFR 40.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... require all joint consumers to opt out before it implements any opt out direction. (5) Example. If John... John's address, the bank may do any of the following, but it must explain in its opt out notice which opt out policy the bank will follow: (i) Send a single opt out notice to John's address, but the...

  7. Apple Germplasm

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Plant Genetic Resources Unit (PGRU) in Geneva, NY part of the USDA-ARS National Plant Germplasm System. The PGRU maintains 55 species of apple (Malus) in both field and seed collections. The main field collection of apples has 2621 diverse clones grafted onto EMLA 9 rootstock. Ninety-seven p...

  8. Traj_opt User's Guide

    NASA Technical Reports Server (NTRS)

    Saunders, David A.

    2005-01-01

    Trajectory optimization program Traj_opt was developed at Ames Research Center to help assess the potential benefits of ultrahigh temperature ceramic materials applied to reusable space vehicles with sharp noses and wing leading edges. Traj_opt loosely couples the Ames three-degrees-of-freedom trajectory package Traj (see NASA-TM-2004-212847) with the SNOPT optimization package (Stanford University Technical Report SOL 98-1). Traj_opt version January 22, 2003 is covered by this user guide. The program has been applied extensively to entry and ascent abort trajectory calculations for sharp and blunt crew transfer vehicles. The main optimization variables are control points for the angle of attack and bank angle time histories. No propulsion options are provided, but numerous objective functions may be specified and the nonlinear constraints implemented include a distributed surface heating constraint capability. Aero-capture calculations are also treated with an option to minimize orbital eccentricity at apoapsis. Traj_opt runs efficiently on a single processor, using forward or central differences for the gradient calculations. Results may be displayed conveniently with Gnuplot scripts. Control files recommended for five standard reentry and ascent abort trajectories are included along with detailed descriptions of the inputs and outputs.

  9. Newton's Apple

    ERIC Educational Resources Information Center

    Hendry, Archibald W.

    2007-01-01

    Isaac Newton may have seen an apple fall, but it was Robert Hooke who had a better idea of where it would land. No one really knows whether or not Isaac Newton actually saw an apple fall in his garden. Supposedly it took place in 1666, but it was a tale he told in his old age more than 60 years later, a time when his memory was failing and his…

  10. 12 CFR 573.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... joint consumers to opt out before you implement any opt out direction. (5) Example. If John and Mary have a joint checking account with you and arrange for you to send statements to John's address, you... follow: (i) Send a single opt out notice to John's address, but you must accept an opt out direction...

  11. Traveling Apples.

    ERIC Educational Resources Information Center

    Rowland Unified School District, Rowland Heights, CA.

    Teacher-developed materials for a basic computer literacy and utilization program for elementary students in grades 3-6 are included in this 4-part packet, which was originally prepared for use with or without the Apple IIe "traveling" microcomputers shared by 15 Rowland Unified School District elementary schools. Implementation…

  12. Cancer chemopreventive potential of apples, apple juice, and apple components.

    PubMed

    Gerhauser, Clarissa

    2008-10-01

    Apples ( MALUS sp., Rosaceae) are a rich source of nutrient as well as non-nutrient components and contain high levels of polyphenols and other phytochemicals. Main structural classes of apple constituents include hydroxycinnamic acids, dihydrochalcones, flavonols (quercetin glycosides), catechins and oligomeric procyanidins, as well as triterpenoids in apple peel and anthocyanins in red apples. Several lines of evidence suggest that apples and apple products possess a wide range of biological activities which may contribute to health beneficial effects against cardiovascular disease, asthma and pulmonary dysfunction, diabetes, obesity, and cancer (reviewed by Boyer and Liu, Nutr J 2004). The present review will summarize the current knowledge on potential cancer preventive effects of apples, apple juice and apple extracts (jointly designated as apple products). In brief, apple extracts and components, especially oligomeric procyanidins, have been shown to influence multiple mechanisms relevant for cancer prevention in IN VITRO studies. These include antimutagenic activity, modulation of carcinogen metabolism, antioxidant activity, anti-inflammatory mechanisms, modulation of signal transduction pathways, antiproliferative and apoptosis-inducing activity, as well as novel mechanisms on epigenetic events and innate immunity. Apple products have been shown to prevent skin, mammary and colon carcinogenesis in animal models. Epidemiological observations indicate that regular consumption of one or more apples a day may reduce the risk for lung and colon cancer.

  13. Sex, Gender, and Aspirations to Top Management: Who's Opting out? Who's Opting in?

    ERIC Educational Resources Information Center

    Powell, Gary N.; Butterfield, D. Anthony

    2013-01-01

    The "opt-out revolution" has become a much-discussed phenomenon over the last decade. According to media reports, highly educated women are increasingly opting out of careers that would place them on the fast track to top management levels. However, little attention has been devoted to whether the opt-out revolution may also apply to highly…

  14. 16 CFR 313.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... (5) Example. If John and Mary have a joint credit card account with you and arrange for you to send statements to John's address, you may do any of the following, but you must explain in your opt out notice which opt out policy you will follow: (i) Send a single opt out notice to John's address, but you...

  15. 17 CFR 160.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... direction. (5) Example. If John and Mary have a joint trading account with you and arrange for you to send statements to John's address, you may do any of the following, but you must explain in your opt out notice which opt out policy you will follow: (i) Send a single opt out notice to John's address, but you...

  16. 12 CFR 216.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... direction. (5) Example. If John and Mary have a joint checking account with you and arrange for you to send statements to John's address, you may do any of the following, but you must explain in your opt out notice which opt out policy you will follow: (i) Send a single opt out notice to John's address, but you...

  17. 12 CFR 332.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Form of opt out notice to consumers; opt out methods. 332.7 Section 332.7 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND..., electronically. (2) When a customer relationship terminates, the customer's opt out direction continues to...

  18. 17 CFR 248.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.7 Form of opt out notice to consumers; opt... the right to disclose nonpublic personal information about your consumer to a nonaffiliated...

  19. 17 CFR 248.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.7 Form of opt out notice to consumers; opt... the right to disclose nonpublic personal information about your consumer to a nonaffiliated...

  20. 17 CFR 248.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.7 Form of opt out notice to consumers; opt... the right to disclose nonpublic personal information about your consumer to a nonaffiliated...

  1. 17 CFR 248.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... consumers; opt out methods. 248.7 Section 248.7 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.7 Form of opt out notice to consumers;...

  2. The apple genome: ripe for harvest

    Technology Transfer Automated Retrieval System (TEKTRAN)

    An international consortium of plant report sequencing of the cultivated apple (Malus x domestica) genome (Velasco et al., this issue). Apples are among the most widely grown and consumed fruits in temperate regions of the world. This is in part due to years of extensive breeding and selection the ...

  3. High resolution visualization of USArray data on a 50 megapixel display using OptIPuter technologies.

    NASA Astrophysics Data System (ADS)

    Nayak, A. M.; Vernon, F.; Kent, G.; Orcutt, J.; Kilb, D.; Newman, R.; Smarr, L.; Defanti, T.; Leigh, J.; Renambot, L.; Johnson, A.

    2004-12-01

    A 50 megapixel display wall is under construction at the Cecil H. & Ida M. Green Institute of Geophysics and Planetary Physics (IGPP) for the display of multiple interactive 3D visualizations of various geophysical datasets. This system is designed through collaboration between major NSF funded projects such as OptIPuter and USArray (Earthscope), and will allow researchers to visually analyze data and present results at extremely high resolution. The OptIPuter project (www.optiputer.net) leverages the capabilities of dedicated optical networks that interconnect instruments, processors, computer storage and visualization resources to aid in Earth Sciences research. This system comprises a cluster of seven Apple Power Mac G5 machines and twelve Apple 30" LCD screens (of maximum resolution 2560 x 1600 each) tiled to form a 4x3 array and will be the first Apple-driven tiled display to our knowledge. The Antelope software will be used for seismic data monitoring and archiving along with web-based analytical tools developed at the Array Network Facility (ANF http://anf.ucsd.edu/) at IGPP. OptIPuter software (developed by the Electronic Visualization Laboratory) such as JuxtaView (an image viewer for interacting with remotely located extremely high resolution 2D images) and Vol-a-Tile (interactive volume rendering software allowing navigation into gigabyte-sized seismic volumes) will also be used. Interactive visualizations created by scientists at IGPP that overlay heterogeneous datasets such as seismic profiles, geology strata, earthquake locations, bathymetry and high resolution satellite imagery and aerial photos, using the Fledermaus software will also be viewed. The configuration of each cluster node is: dual CPU 2.5 GHz PowerPC G5, 8 GB RAM, 500 GB disk space, NVIDIA Ultra 6800 GeForce card, and the nodes are interconnected over gigabit Ethernet. This system will also be part of the OptIPuter infrastructure, with fiber connections to the OptIPuter CAVEwave on the

  4. Are Red Apples Sweeter Than Green Apples?

    ERIC Educational Resources Information Center

    Fraser, Chris

    1999-01-01

    Describes how a classroom observation of apples led to the development of a science project. Discusses the correlation between the greenness and the acidity of apples. Finds that the greener the apple, the lower its pH, and thus the more acidic and less sweet it tastes. (Author/CCM)

  5. Opt-in medical management strategies.

    PubMed

    Fetterolf, Donald; Olson, Marty

    2008-02-01

    Historically, health plans and disease management companies have employed "opt-out" strategies for evaluating medical management outcomes across larger populations, targeting the entire population of eligible individuals and allowing those not interested to opt out. Recent observations that the predominant effort of these programs is on high-risk patients has lead some managers to suggest that the focus be on only those individuals with an anticipated higher effectiveness and lower cost to the payers of such services. They believe such "opt-in" models, in which only higher risk participants are targeted and enrolled, will deliver higher value. The use of common opt-in models, however, is not only methodologically unsound, but experience in the field suggests there may be less overall effect as well. Calculation methods for developing impact remain extremely sensitive to methodology

  6. Acid Rain Program Opt-in Factsheet

    EPA Pesticide Factsheets

    Learn about the Opt-in Program, which allows sources not required to participate in the Acid Rain Program the opportunity to enter the program on a voluntary basis and receive Acid Rain Program allowances.

  7. Inclusion of Residual Tissue in Biobanks: Opt-In or Opt-Out?

    PubMed Central

    Giesbertz, Noor A. A.; Bredenoord, Annelien L.; van Delden, Johannes J. M.

    2012-01-01

    Residual samples are an important source of tissue for biobanks. They refer to leftover tissue that is obtained in the course of clinical care. Residual samples can be included through an opt-in method—that is, a person explicitly expresses consent to include residual tissue—or an opt-out method—that is, the tissue is stored unless a person explicitly refuses. At the moment there is a renewed interest in the appropriate method for the inclusion of residual samples in biobanks. The expansion of biobanks and rapid developments in biomedical research underscore the need to evaluate the proper procedure. In this article we revisit the arguments in favor and against opt-in and opt-out methods for residual tissue research. We conclude firstly that an opt-out method is only justifiable when certain conditions are met: (1) awareness has to be raised, (2) sufficient information has to be provided, and (3) a genuine possibility to object has to be offered. An opt-out procedure that fulfills these conditions can be called a “thick” opt-out method. As a consequence, the dichotomy between opt-in and opt-out is less stark than usually suggested, as both methods require a certain amount of effort. Secondly, we conclude that because of the diversity of tissue and research, not every situation can be treated alike. There are at least four situations that require opt-in procedures: (1) research with higher risks or increased burdens, (2) the use of controversial or high-impact techniques, (3) research on sensitive tissue types, and (4) research involving vulnerable patients. We suggest that further interdisciplinary debate should answer the question when to opt-in or when to opt-out. PMID:22899893

  8. 40 CFR 74.14 - Opt-in permit process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... intention to become an opt-in source and as a withdrawal of the opt-in permit application. (5) Issuance of... designated representative of a combustion or process source may submit an opt-in permit application and a... information. Regardless of whether the opt-in permit application is complete, the Administrator or...

  9. 17 CFR 248.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.7 Form of opt out notice... you disclose or reserve the right to disclose nonpublic personal information about your consumer to...

  10. Elementary, My Dear Apple.

    ERIC Educational Resources Information Center

    Schilling, Robert

    1981-01-01

    A review of "Elementary, My Dear Apple," a commercial software package for the Apple II microcomputer. The package contains four computer programs which present elementary-level spelling, math, and economics learning activities in game-like formats. (SJL)

  11. 40 CFR 96.84 - Opt-in process.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.84 Opt-in process. The permitting authority will issue or deny a NOX Budget opt-in permit...

  12. The Apple IIc.

    ERIC Educational Resources Information Center

    Freiberger, Paul

    1984-01-01

    Description of the portable Apple IIc includes its flat panel display; a new microprocessor, the 65CO2; its new design language; layout; documentation, including interactive tutorials; software support; and cost. Apple IIc's competitors and its new printer, the Scribe, are also discussed. (MBR)

  13. 16 CFR 313.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... methods. 313.7 Section 313.7 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS... writing or, if the consumer agrees, electronically. (d) Joint relationships. (1) If two or more consumers... how you will treat an opt out direction by a joint consumer (as explained in paragraph...

  14. Opting Out of Opting Out: A Natural History of a Policy That Failed.

    ERIC Educational Resources Information Center

    Fitz, John; Halpin, David; Power, Sally

    This paper uses data drawn from two projects funded by the Economic and Social Research Council of England and Wales. It covers the years 1990-94 and examines the effects of the Education Reform Act, which allowed state schools to "opt out" or leave the control of their Local Education Authority (LEA) and still receive funding. Such…

  15. Apple rootstock evaluation for apple replant disease

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Twenty-nine rootstocks from the Cornell-Geneva rootstock breeding program, some Budagovski rootstocks, M.9T337 and M.26EMLA were screened for apple replant disease (ARD) tolerance at Geneva, New York in 2008. Bench grafted rootstocks were planted in pots with two types of soil –clay loam and sandy l...

  16. OptQC v1.3: An (updated) optimized parallel quantum compiler

    NASA Astrophysics Data System (ADS)

    Loke, T.; Wang, J. B.

    2016-10-01

    We present a revised version of the OptQC program of Loke et al. (2014) [1]. We have removed the simulated annealing process in favour of a descending random walk. We have also introduced a new method for iteratively generating permutation matrices during the random walk process, providing a reduced total cost for implementing the quantum circuit. Lastly, we have also added a synchronization mechanism between threads, giving quicker convergence to more optimal solutions.

  17. The Diminishing Apple.

    ERIC Educational Resources Information Center

    Kelly, Catherine

    2002-01-01

    Introduces the Apple Ocean activity which teaches about the diminishing natural resources of the earth including drinkable water, habitable land, and productive areas while working with fractions, ratios, and proportions. (YDS)

  18. 17 CFR 162.6 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... PROTECTION OF CONSUMER INFORMATION UNDER THE FAIR CREDIT REPORTING ACT Business Affiliate Marketing Rules... elect to opt out by any reasonable method. (3) If the opt-out notice is sent via e-mail (where the consumer has agreed to receive disclosures by e-mail), the consumer is given 30 days after the e-mail...

  19. 40 CFR 96.184 - Opt-in process.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Opt-in process. 96.184 Section 96.184 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR NOX Opt-in...

  20. 16 CFR 680.24 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... form that requires consumers to write a “yes” or “no” to indicate their opt-out preference or that... information about a consumer that you receive from an affiliate to make a solicitation to the consumer about your products or services, unless the consumer is provided a reasonable opportunity to opt out,...

  1. 12 CFR 222.24 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... consumers to write a “yes” or “no” to indicate their opt-out preference or that requires the consumer to... opt out. (a) In general. You must not use eligibility information about a consumer that you receive from an affiliate to make a solicitation to the consumer about your products or services, unless...

  2. 12 CFR 41.24 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... part of proceeding with the transaction, whether to opt out before completing the transaction. There is... transaction, and is not permitted to complete the transaction without making a choice. There is a simple... e-mail is sent to elect to opt out by any reasonable means. (3) At the time of an...

  3. Conscience in the Curriculum, Not Opted Out of It

    ERIC Educational Resources Information Center

    Stitzlein, Sarah M.

    2014-01-01

    A small, but growing, number of states have legislation that protects the conscience of parents by allowing them to opt out of teaching practices and content. Most notably, HB 542 in New Hampshire allows parents to opt their children out of the teaching of any material or through any pedagogical style that they find "objectionable" to…

  4. 40 CFR 96.84 - Opt-in process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... a unit for which an initial application for a NOX Budget opt-in permit under § 96.83 is submitted... initial application for a NOX Budget opt-in permit under § 96.83. A monitoring plan is sufficient, for... permit on the NOX authorized account representative of the unit. (e) Confirmation of intention to...

  5. 12 CFR 41.27 - Renewal of opt-out.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Marketing § 41.27 Renewal of opt-out. (a) Renewal notice and opt-out requirement. (1) In general. After the... card, insurance, and securities companies,” or by listing the name of each affiliate providing the... banking, credit card, insurance, and securities companies,” or by listing the name of each...

  6. 12 CFR 41.27 - Renewal of opt-out.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Marketing § 41.27 Renewal of opt-out. (a) Renewal notice and opt-out requirement. (1) In general. After the... card, insurance, and securities companies,” or by listing the name of each affiliate providing the... banking, credit card, insurance, and securities companies,” or by listing the name of each...

  7. 17 CFR 162.6 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Reasonable opportunity to opt out. 162.6 Section 162.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION... Marketing Rules § 162.6 Reasonable opportunity to opt out. (a) In general. A covered affiliate must not...

  8. The opt-in program: Creating opportunities for cost savings

    SciTech Connect

    Klinger, A.

    1995-12-31

    The final regulation implementing the opt-in program for combustion sources will be published within the next month. This regulation will allow combustion sources (i.e., non-affected boilers, turbines, and internal combustion engines) the opportunity to enter the Acid Rain Program on a voluntary basis. Although anyone can buy and sell allowances, opt-in sources will receive their own allowance allocation and profit from the sale of excess allowances. Excess allowances can only be generated, though, through emission reductions at the opt-in source. This presentation provides an overview of the opt-in program and focuses on the program`s motivation to lower the cost of acid rain control. The opt-in program will not reduce emissions in the aggregate, but instead offers incentives for emissions reductions at non-affected sources. By creating excess allowances, an opt-in source has a means for recouping the market value of those reductions through Acid Rain allowances. Lower cost opportunities for reducing sulfur dioxide at opt-in sources can, through allowance trading, reduce the costs of compliance for affected utility units.

  9. optPBN: An Optimisation Toolbox for Probabilistic Boolean Networks

    PubMed Central

    Trairatphisan, Panuwat; Mizera, Andrzej; Pang, Jun; Tantar, Alexandru Adrian; Sauter, Thomas

    2014-01-01

    Background There exist several computational tools which allow for the optimisation and inference of biological networks using a Boolean formalism. Nevertheless, the results from such tools yield only limited quantitative insights into the complexity of biological systems because of the inherited qualitative nature of Boolean networks. Results We introduce optPBN, a Matlab-based toolbox for the optimisation of probabilistic Boolean networks (PBN) which operates under the framework of the BN/PBN toolbox. optPBN offers an easy generation of probabilistic Boolean networks from rule-based Boolean model specification and it allows for flexible measurement data integration from multiple experiments. Subsequently, optPBN generates integrated optimisation problems which can be solved by various optimisers. In term of functionalities, optPBN allows for the construction of a probabilistic Boolean network from a given set of potential constitutive Boolean networks by optimising the selection probabilities for these networks so that the resulting PBN fits experimental data. Furthermore, the optPBN pipeline can also be operated on large-scale computational platforms to solve complex optimisation problems. Apart from exemplary case studies which we correctly inferred the original network, we also successfully applied optPBN to study a large-scale Boolean model of apoptosis where it allows identifying the inverse correlation between UVB irradiation, NFκB and Caspase 3 activations, and apoptosis in primary hepatocytes quantitatively. Also, the results from optPBN help elucidating the relevancy of crosstalk interactions in the apoptotic network. Summary The optPBN toolbox provides a simple yet comprehensive pipeline for integrated optimisation problem generation in the PBN formalism that can readily be solved by various optimisers on local or grid-based computational platforms. optPBN can be further applied to various biological studies such as the inference of gene regulatory

  10. About APPLE II Operation

    SciTech Connect

    Schmidt, T.; Zimoch, D.

    2007-01-19

    The operation of an APPLE II based undulator beamline with all its polarization states (linear horizontal and vertical, circular and elliptical, and continous variation of the linear vector) requires an effective description allowing an automated calculation of gap and shift parameter as function of energy and operation mode. The extension of the linear polarization range from 0 to 180 deg. requires 4 shiftable magnet arrrays, permitting use of the APU (adjustable phase undulator) concept. Studies for a pure fixed gap APPLE II for the SLS revealed surprising symmetries between circular and linear polarization modes allowing for simplified operation. A semi-analytical model covering all types of APPLE II and its implementation will be presented.

  11. Determination of amygdalin in apple seeds, fresh apples and processed apple juices.

    PubMed

    Bolarinwa, Islamiyat F; Orfila, Caroline; Morgan, Michael R A

    2015-03-01

    Cyanogenic glycosides are natural plant toxicants. Action by endogenous plant enzymes can release hydrogen cyanide causing potential toxicity issues for animals including humans. We have quantified amygdalin in seeds from different apple varieties, determined the effects of processing on the amygdalin content of apple juice and quantified amygdalin in commercially-available apple juices. Amygdalin contents of seeds from fifteen varieties of apples ranged from 1 mg g(-1) to 4 mg g(-1). The amygdalin content of commercially-available apple juice was low, ranging from 0.01 to 0.04 mg ml(-1) for pressed apple juice and 0.001-0.007 mg ml(-1) for long-life apple juice. Processing led to juice with low amygdalin content, ranging from 0.01 mg ml(-1) to 0.08 mg ml(-1). The results presented show that the amygdalin contents of commercially-available apple juices are unlikely to present health problems to consumers.

  12. 'Opt-out' testing lacks patient-friendly system.

    PubMed

    Bateman, Chris

    2010-05-04

    The hugely welcome government-led initiative to pro-actively offer 'opt-out' HIV testing to patients at its clinics and hospitals needs hefty back-up resources to ensure patient retention and earlier presentation.

  13. The Apple III.

    ERIC Educational Resources Information Center

    Ditlea, Steve

    1982-01-01

    Describes and evaluates the features, performance, peripheral devices, available software, and capabilities of the Apple III microcomputer. The computer's operating system, its hardware, and the commercially produced software it accepts are discussed. Specific applications programs for financial planning, accounting, and word processing are…

  14. Apple mosaic virus

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apple mosaic virus (ApMV), a member of the ilarvirus group, naturally infects Betula, Aesculus, Humulus, and several crop genera in the family Rosaceae (Malus, Prunus, Rosa and Rubus). ApMV was first reported in Rubus in several blackberry and raspberry cultivars in the United States and subsequentl...

  15. 40 CFR 97.85 - NOX Budget opt-in permit contents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false NOX Budget opt-in permit contents. 97... (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS Individual Unit Opt-ins. § 97.85 NOX Budget opt-in permit contents. (a) Each NOX Budget opt-in permit will contain all...

  16. 40 CFR 96.85 - NOX Budget opt-in permit contents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false NOX Budget opt-in permit contents. 96... (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.85 NOX Budget opt-in permit contents. (a) Each NOX Budget opt-in...

  17. 40 CFR 96.85 - NOX Budget opt-in permit contents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false NOX Budget opt-in permit contents. 96... (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO 2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.85 NOX Budget opt-in permit contents. (a) Each NOX Budget opt-in...

  18. 40 CFR 97.85 - NOX Budget opt-in permit contents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false NOX Budget opt-in permit contents. 97... (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS Individual Unit Opt-ins § 97.85 NOX Budget opt-in permit contents. (a) Each NOX Budget opt-in permit will contain all...

  19. 40 CFR 97.85 - NOX Budget opt-in permit contents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false NOX Budget opt-in permit contents. 97... (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS Individual Unit Opt-ins. § 97.85 NOX Budget opt-in permit contents. (a) Each NOX Budget opt-in permit will contain all...

  20. 40 CFR 96.85 - NOX Budget opt-in permit contents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.85 NOX Budget opt-in permit contents. (a) Each NOX Budget opt-in permit... 40 Protection of Environment 21 2011-07-01 2011-07-01 false NOX Budget opt-in permit contents....

  1. 40 CFR 96.85 - NOX Budget opt-in permit contents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.85 NOX Budget opt-in permit contents. (a) Each NOX Budget opt-in permit... 40 Protection of Environment 20 2010-07-01 2010-07-01 false NOX Budget opt-in permit contents....

  2. 16 CFR 313.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Delivering privacy and opt out notices. 313... CONGRESS PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 313.9 Delivering privacy and opt out notices. (a) How to provide notices. You must provide any privacy notices and opt...

  3. 12 CFR 216.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 2 2012-01-01 2012-01-01 false Delivering privacy and opt out notices. 216.9... PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) Privacy and Opt Out Notices § 216.9 Delivering privacy and opt out notices. (a) How to provide notices. You must provide any privacy notices and opt...

  4. 12 CFR 332.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Delivering privacy and opt out notices. 332.9... GENERAL POLICY PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 332.9 Delivering privacy and opt out notices. (a) How to provide notices. You must provide any privacy notices and opt...

  5. 16 CFR 313.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Delivering privacy and opt out notices. 313... CONGRESS PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 313.9 Delivering privacy and opt out notices. (a) How to provide notices. You must provide any privacy notices and opt...

  6. 12 CFR 716.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Delivering privacy and opt out notices. 716.9... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 716.9 Delivering privacy and opt out notices. (a) How to provide notices. You must provide any privacy notices and opt out...

  7. 12 CFR 216.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 2 2014-01-01 2014-01-01 false Delivering privacy and opt out notices. 216.9... PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) Privacy and Opt Out Notices § 216.9 Delivering privacy and opt out notices. (a) How to provide notices. You must provide any privacy notices and opt...

  8. Apple Strength Issues

    SciTech Connect

    Syn, C

    2009-12-22

    Strength of the apple parts has been noticed to decrease, especially those installed by the new induction heating system since the LEP campaign started. Fig. 1 shows the ultimate tensile strength (UTS), yield strength (YS), and elongation of the installed or installation-simulated apples on various systems. One can clearly see the mean values of UTS and YS of the post-LEP parts decreased by about 8 ksi and 6 ksi respectively from those of the pre-LEP parts. The slight increase in elongation seen in Fig.1 can be understood from the weak inverse relationship between the strength and elongation in metals. Fig.2 shows the weak correlation between the YS and elongation of the parts listed in Fig. 1. Strength data listed in Figure 1 were re-plotted as histograms in Figs. 3 and 4. Figs. 3a and 4a show histograms of all UTS and YS data. Figs. 3b and 4b shows histograms of pre-LEP data and Figs. 3c and 4c of post-LEP data. Data on statistical scatter of tensile strengths have been rarely published by material suppliers. Instead, only the minimum 'guaranteed' strength data are typically presented. An example of strength distribution of aluminum 7075-T6 sheet material, listed in Fig. 5, show that its scatter width of both UTS and YS for a single sheet can be about 6 ksi and for multi-lot scatter can be as large as 11 ksi even though the sheets have been produced through well-controlled manufacturing process. By approximating the histograms shown in Figs. 3 and 4 by a Gaussian or similar type of distribution curves, one can plausibly see the strength reductions in the later or more recent apples. The pre-LEP data in Figs. 3b and 4b show wider scatter than the post-LEP data in Figs. 3c and 4c and seem to follow the binomial distribution of strength indicating that the apples might have been made from two different lots of material, either from two different vendors or from two different melts of perhaps slightly different chemical composition by a single vendor. The post

  9. Apple Image Processing Educator

    NASA Technical Reports Server (NTRS)

    Gunther, F. J.

    1981-01-01

    A software system design is proposed and demonstrated with pilot-project software. The system permits the Apple II microcomputer to be used for personalized computer-assisted instruction in the digital image processing of LANDSAT images. The programs provide data input, menu selection, graphic and hard-copy displays, and both general and detailed instructions. The pilot-project results are considered to be successful indicators of the capabilities and limits of microcomputers for digital image processing education.

  10. Difficult OptEase Filter Retrievals After Prolonged Indwelling Times

    SciTech Connect

    Van Ha, Thuong G. Kang, Lisa; Lorenz, Jonathan; Zangan, Steven; Navuluri, Rakesh; Straus, Christopher; Funaki, Brian

    2013-08-01

    PurposeThe OptEase vena cave filter (Cordis, Piscataway, NJ) is commercially available as a retrievable or permanent filter with short recommended indwelling time, presumably due to extensive contact of the filter side struts with the inferior vena cava wall and subsequent neointimal hyperplasia leading to incorporation. Our purpose was to evaluate OptEase filter retrievals with a long indwelling time period that required unconventional retrieval techniques.Materials and MethodsWe retrospectively reviewed patients who underwent OptEase filter retrieval with long undwelling times requiring additional maneuvers for retrieval. Techniques used included rigid endobronchial forceps dissection and wire-through-loop snare. Each patient underwent postretrieval venogram to evaluate for possible complications. In addition, patients had clinical follow-up 2 weeks after the retrieval procedure.ResultsThere were three patients (2 women, 1 man; average age 64 years) who underwent OptEase filter retrieval. The mean indwelling time was 6.4 months. The indwelling filters were successfully retrieved. There were no complications. Postprocedural follow-up showed no clinical pathology.ConclusionUnconventional techniques aided in the retrieval of OptEase filters with long indwelling times.

  11. Polyphenol profiles of apple juices.

    PubMed

    Kahle, Kathrin; Kraus, Michael; Richling, Elke

    2005-08-01

    Focusing on 17 constituents, the polyphenol profiles of juices freshly made from various dessert (n = 4) and cider apple cultivars (n = 7) as well as commercially available apple juices (n = 24) were investigated using high-performance liquid chromatography-photodiode array detection (HPLC-DAD) and (HPLC)-electrospray ionization-tandem mass spectrometry (ESI(neg)-MS/MS) analyses. Significant differences in the total polyphenol content as well as the profiles of the apple cultivars under study were observed. For dessert apples the total polyphenol content ranged from 154 to 178 mg/L, whereas for 'old' German cider apple cultivars 261-970 mg/L were determined. Boskoop showed the highest (970 mg/L) and Granny Smith the lowest (154 mg/L) polyphenol content of the freshly prepared samples under study. Hydroxycinnamic acids, with chlorogenic acid as dominating constituent, ranged from 57 to 68 mg/L as well as from 134-593 mg/L in juices made from dessert apples and that from cider apples, respectively. Dessert apple juices showed lower contents of dihydrochalcones (10-35 mg/L) and flavan-3-ols (50-95 mg/L) compared to that of cider apples (34-171 mg/L and 70-393 mg/L, respectively). Quercetin and its derivatives were found from 0.4-4 mg/L and 0.4-27 mg/L in juices made from dessert apples and that of cider apples, respectively. Compared with freshly made juices, lower contents of polyphenols were determined in the commercial samples under study. Amounts ranging from 110-459 mg/L, dominated by chlorogenic acid with concentrations from 53-217 mg/L, were determined. Information about cultivar-typical apple polyphenol content and profile is important for bioactivity studies and, consequently, essential for the development of consumer-relevant products with particular nutritional functionalities.

  12. Volatility of patulin in apple juice.

    PubMed

    Kryger, R A

    2001-08-01

    Patulin is a mycotoxin produced by certain fungi, such as those found commonly on apples. The patulin content of apple juice is a regulatory concern because patulin is a suspected carcinogen and mutagen. A simple model of the apple juice concentration process was carried out to examine the possible contamination of patulin in apple aroma, a distillate produced commercially in the concentration of apple juice. The results show no evidence for patulin volatility, and document a reduction in patulin content by at least a factor of 250 in the apple distillate obtained from apple juice. Furthermore, a survey of several commercial apple aroma samples found no evidence of patulin content.

  13. Management of apple anthracnose canker

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apple anthracnose (caused by Neofabraea malicorticis anamorph Cryptosporiopsis curvispora) is a fungal disease that causes cankers on trees and ‘Bull’s-eye rot’ on fruit. In western Washington, it is the canker phase of apple anthracnose that is considered most serious as it can result in death of ...

  14. Tropical Soda Apple (Solanum viarum)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Tropical soda apple (Solanum viarum Dunal), a perennial shrub, is a Federal Noxious Weed that continues to spread at an alarming rate in the southeastern United States. Information is provided on the impact of tropical soda apple on agricultural and natural areas, federal regulations for restricted...

  15. Apple rootstock resistance to drought

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Water for irrigation will likely be less available in apple-growing regions due to climate change and competition with human needs other than agriculture. Apple cultivars and rootstocks may differ in water use necessary for acceptable cropping. In two greenhouse experiments in 2014 and 2015, roots...

  16. The gravity apple tree

    NASA Astrophysics Data System (ADS)

    Espinosa Aldama, Mariana

    2015-04-01

    The gravity apple tree is a genealogical tree of the gravitation theories developed during the past century. The graphic representation is full of information such as guides in heuristic principles, names of main proponents, dates and references for original articles (See under Supplementary Data for the graphic representation). This visual presentation and its particular classification allows a quick synthetic view for a plurality of theories, many of them well validated in the Solar System domain. Its diachronic structure organizes information in a shape of a tree following similarities through a formal concept analysis. It can be used for educational purposes or as a tool for philosophical discussion.

  17. The domestication and evolutionary ecology of apples.

    PubMed

    Cornille, Amandine; Giraud, Tatiana; Smulders, Marinus J M; Roldán-Ruiz, Isabel; Gladieux, Pierre

    2014-02-01

    The cultivated apple is a major fruit crop in temperate zones. Its wild relatives, distributed across temperate Eurasia and growing in diverse habitats, represent potentially useful sources of diversity for apple breeding. We review here the most recent findings on the genetics and ecology of apple domestication and its impact on wild apples. Genetic analyses have revealed a Central Asian origin for cultivated apple, together with an unexpectedly large secondary contribution from the European crabapple. Wild apple species display strong population structures and high levels of introgression from domesticated apple, and this may threaten their genetic integrity. Recent research has revealed a major role of hybridization in the domestication of the cultivated apple and has highlighted the value of apple as an ideal model for unraveling adaptive diversification processes in perennial fruit crops. We discuss the implications of this knowledge for apple breeding and for the conservation of wild apples.

  18. Comment on “Theoretical analysis of high-field transport in graphene on a substrate” [J. Appl. Phys. 116, 034507 (2014)

    SciTech Connect

    Tan, Michael L. P.; Arora, Vijay K.

    2014-12-21

    In a recent article, Serov et al. [J. Appl. Phys. 116, 034507 (2014)] claim: “This study represents the first time that the high-field behavior in graphene on a substrate was investigated taking into account intrinsic graphene properties,” ignoring the most recent anisotropic distribution function [V. K. Arora et al., J. Appl. Phys. 112, 114330 (2012)] also published in J. Appl. Phys., targeting the same experimental data [V. E. Dorgan et al., Appl. Phys. Lett. 97, 082112 (2010)]. The claim of Serov et al. of being first is refuted and many shortcomings of the hydrodynamic model for a highly quantum and degenerate graphene nanolayer are pointed out.

  19. 40 CFR 97.284 - Opt-in process.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... monitored and reported in accordance with subpart HHH of this part. A determination of sufficiency shall not... rate and the heat input of the unit and all other applicable parameters, in accordance with subpart HHH... subpart HHH of this part and continuing until a CAIR opt-in permit is denied under § 97.284(f) or, if...

  20. 40 CFR 97.284 - Opt-in process.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... monitored and reported in accordance with subpart HHH of this part. A determination of sufficiency shall not... rate and the heat input of the unit and all other applicable parameters, in accordance with subpart HHH... subpart HHH of this part and continuing until a CAIR opt-in permit is denied under § 97.284(f) or, if...

  1. 40 CFR 97.284 - Opt-in process.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... monitored and reported in accordance with subpart HHH of this part. A determination of sufficiency shall not... rate and the heat input of the unit and all other applicable parameters, in accordance with subpart HHH... subpart HHH of this part and continuing until a CAIR opt-in permit is denied under § 97.284(f) or, if...

  2. 40 CFR 97.284 - Opt-in process.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... monitored and reported in accordance with subpart HHH of this part. A determination of sufficiency shall not... rate and the heat input of the unit and all other applicable parameters, in accordance with subpart HHH... subpart HHH of this part and continuing until a CAIR opt-in permit is denied under § 97.284(f) or, if...

  3. Women "Opting out" of Academia: At What Cost?

    ERIC Educational Resources Information Center

    Schneider, Beth Z.; Carden, William; Francisco, Alyson; Jones, Thomas O., Jr.

    2011-01-01

    Previous research has examined the phenomenon of women "opting out" of the corporate environment. Much of this research has examined both "pull" factors--those of home and family life, and "push" factors--those within the organization which create a competitive environment where women feel they cannot achieve the same measure of success as their…

  4. 40 CFR 74.12 - Opt-in permit contents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... be included in the Acid Rain permit. (b) Scope. The opt-in permit provisions shall apply only to the... provision that participation of a combustion or process source in the Acid Rain Program may be terminated... deemed to be operating in compliance with the Acid Rain Program, except as provided in § 72.9(g)(6)...

  5. 40 CFR 74.12 - Opt-in permit contents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... be included in the Acid Rain permit. (b) Scope. The opt-in permit provisions shall apply only to the... provision that participation of a combustion or process source in the Acid Rain Program may be terminated... deemed to be operating in compliance with the Acid Rain Program, except as provided in § 72.9(g)(6)...

  6. 40 CFR 74.12 - Opt-in permit contents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... be included in the Acid Rain permit. (b) Scope. The opt-in permit provisions shall apply only to the... provision that participation of a combustion or process source in the Acid Rain Program may be terminated... deemed to be operating in compliance with the Acid Rain Program, except as provided in § 72.9(g)(6)...

  7. 40 CFR 74.12 - Opt-in permit contents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... be included in the Acid Rain permit. (b) Scope. The opt-in permit provisions shall apply only to the... provision that participation of a combustion or process source in the Acid Rain Program may be terminated... deemed to be operating in compliance with the Acid Rain Program, except as provided in § 72.9(g)(6)...

  8. 40 CFR 74.12 - Opt-in permit contents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... be included in the Acid Rain permit. (b) Scope. The opt-in permit provisions shall apply only to the... provision that participation of a combustion or process source in the Acid Rain Program may be terminated... deemed to be operating in compliance with the Acid Rain Program, except as provided in § 72.9(g)(6)...

  9. 12 CFR 571.24 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... completing a form that requires consumers to write a “yes” or “no” to indicate their opt-out preference or... eligibility information about a consumer that you receive from an affiliate to make a solicitation to the consumer about your products or services, unless the consumer is provided a reasonable opportunity to...

  10. 12 CFR 717.24 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... completing a form that requires consumers to write a “yes” or “no” to indicate their opt-out preference or.... You must not use eligibility information about a consumer that you receive from an affiliate to make a solicitation to the consumer about your products or services, unless the consumer is provided a...

  11. 12 CFR 334.24 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...” to indicate their opt-out preference or that requires the consumer to check one of two blank check...) In general. You must not use eligibility information about a consumer that you receive from an affiliate to make a solicitation to the consumer about your products or services, unless the consumer...

  12. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Reasonable opportunity to opt out. 248.124 Section 248.124 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Internet Web site at which the consumer has obtained a product or service. The consumer...

  13. Opting Out: Parents Creating Contested Spaces to Challenge Standardized Tests

    ERIC Educational Resources Information Center

    Mitra, Dana; Mann, Bryan; Hlavacik, Mark

    2016-01-01

    We explore how the opt-out movement has responded to the combination of a stringent federal policy with weak and often variable implementation among the states. Gaps between federal expectations and states' understandings of just how to make NCLB's demands a reality have created policy ambiguity. Parents who oppose standardized testing have…

  14. 17 CFR 162.9 - Renewal of opt out.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Renewal of opt out. 162.9 Section 162.9 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION PROTECTION OF CONSUMER INFORMATION UNDER THE FAIR CREDIT REPORTING ACT Business Affiliate Marketing Rules § 162.9...

  15. 17 CFR 248.127 - Renewal of opt out elections.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Renewal of opt out elections. 248.127 Section 248.127 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.127 Renewal...

  16. 17 CFR 248.127 - Renewal of opt out elections.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Renewal of opt out elections. 248.127 Section 248.127 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.127 Renewal...

  17. 17 CFR 162.6 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Reasonable opportunity to opt out. 162.6 Section 162.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION PROTECTION OF CONSUMER INFORMATION UNDER THE FAIR CREDIT REPORTING ACT Business Affiliate Marketing...

  18. 17 CFR 162.9 - Renewal of opt out.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Renewal of opt out. 162.9 Section 162.9 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION (CONTINUED) PROTECTION OF CONSUMER INFORMATION UNDER THE FAIR CREDIT REPORTING ACT Business Affiliate Marketing...

  19. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Reasonable opportunity to opt out. 248.124 Section 248.124 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.124...

  20. 17 CFR 248.126 - Delivery of opt out notices.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Delivery of opt out notices. 248.126 Section 248.126 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.126...

  1. 17 CFR 248.127 - Renewal of opt out elections.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Renewal of opt out elections. 248.127 Section 248.127 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing §...

  2. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Reasonable opportunity to opt out. 248.124 Section 248.124 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.124...

  3. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Reasonable opportunity to opt out. 248.124 Section 248.124 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.124...

  4. 17 CFR 248.126 - Delivery of opt out notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Delivery of opt out notices. 248.126 Section 248.126 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.126...

  5. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Reasonable opportunity to opt out. 248.124 Section 248.124 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing §...

  6. 17 CFR 162.9 - Renewal of opt out.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Renewal of opt out. 162.9 Section 162.9 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION PROTECTION OF CONSUMER INFORMATION UNDER THE FAIR CREDIT REPORTING ACT Business Affiliate Marketing Rules § 162.9...

  7. 17 CFR 248.127 - Renewal of opt out elections.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Renewal of opt out elections. 248.127 Section 248.127 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.127 Renewal...

  8. 17 CFR 248.127 - Renewal of opt out elections.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Renewal of opt out elections. 248.127 Section 248.127 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.127 Renewal...

  9. 17 CFR 248.126 - Delivery of opt out notices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Delivery of opt out notices. 248.126 Section 248.126 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing §...

  10. 17 CFR 248.126 - Delivery of opt out notices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Delivery of opt out notices. 248.126 Section 248.126 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.126...

  11. 12 CFR 41.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Affiliate Marketing § 41.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be provided... provisions in this subpart or the provisions in section 101 of the Electronic Signatures in Global...

  12. 12 CFR 717.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CREDIT REPORTING Affiliate Marketing § 717.26 Delivery of opt-out notices. (a) In general. The opt-out... Signatures in Global and National Commerce Act, 15 U.S.C. 7001 et seq. (b) Examples of reasonable...

  13. 12 CFR 571.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Affiliate Marketing § 571.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be... provisions in this subpart or the provisions in section 101 of the Electronic Signatures in Global...

  14. 7 CFR 33.5 - Apples.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Apples. 33.5 Section 33.5 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.5 Apples. Apples mean fresh whole...

  15. 7 CFR 33.5 - Apples.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Apples. 33.5 Section 33.5 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.5 Apples. Apples mean fresh whole...

  16. 7 CFR 33.5 - Apples.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 2 2012-01-01 2012-01-01 false Apples. 33.5 Section 33.5 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.5 Apples. Apples mean fresh whole...

  17. 7 CFR 33.5 - Apples.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false Apples. 33.5 Section 33.5 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.5 Apples. Apples mean fresh whole...

  18. 7 CFR 33.5 - Apples.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Apples. 33.5 Section 33.5 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.5 Apples. Apples mean fresh whole...

  19. Horizontal Disc Random Array Performance. Hydrophone Arrays of Omnidirectional, Cardioid, and Iso-Opt Hypercardioid Elements Analyzed for Noise Gain and Directional Response in Vertically Directive Noise

    DTIC Science & Technology

    1979-09-10

    1) HORIC’NTAL-,DISCZAND0,M1 ARA AC.-- Final /1 ~3 rpnfl I I\\of 02 ~~fC’’.,c41jiud, anu iso -npt hyper Octsba 078-Spmef J979 card ioid elemeints...8217 16 onniidirectional. f cardioid, or iso -opt hypercardioid c:lenienrts inl verticallx’ directive mind isotropic ambient sea I noise. Assume that the...is30H. NtIIC wavelength splac:iig is reLliircd if’ 11) is 25 Hz,. 3.Co mpared to a single~ directional element ailone,: al array of I16 iso -Opt h\\v

  20. 40 CFR 96.383 - Applying for CAIR opt-in permit.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CAIR NOX Ozone Season Opt-in Units § 96.383 Applying for CAIR opt-in permit. (a) Applying for initial... NOX Ozone Season opt-in unit in § 96.380 may apply for an initial CAIR opt-in permit at any time... permitting authority, that the unit: (i) Is not a CAIR NOX Ozone Season unit under § 96.304 and is...

  1. 40 CFR 96.383 - Applying for CAIR opt-in permit.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CAIR NOX Ozone Season Opt-in Units § 96.383 Applying for CAIR opt-in permit. (a) Applying for initial... NOX Ozone Season opt-in unit in § 96.380 may apply for an initial CAIR opt-in permit at any time... permitting authority, that the unit: (i) Is not a CAIR NOX Ozone Season unit under § 96.304 and is...

  2. 40 CFR 96.383 - Applying for CAIR opt-in permit.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CAIR NOX Ozone Season Opt-in Units § 96.383 Applying for CAIR opt-in permit. (a) Applying for initial... NOX Ozone Season opt-in unit in § 96.380 may apply for an initial CAIR opt-in permit at any time... permitting authority, that the unit: (i) Is not a CAIR NOX Ozone Season unit under § 96.304 and is...

  3. 12 CFR 41.22 - Scope and duration of opt-out.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Affiliate Marketing § 41.22 Scope and duration of opt-out. (a) Scope of opt-out. (1) In general. Except as... the notice to make solicitations to the consumer. (2) Continuing relationship. (i) In general. If the consumer establishes a continuing relationship with a bank or its affiliate, an opt-out notice may apply...

  4. 12 CFR 334.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND STATEMENTS OF GENERAL POLICY FAIR CREDIT REPORTING Affiliate Marketing § 334.23 Contents of opt... and simple method for the consumer to opt out. (2) Joint relationships. (i) If two or more consumers...) Alternative contents. If the consumer is afforded a broader right to opt out of receiving marketing than...

  5. 17 CFR 162.3 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) The affiliate is identified on or with the marketing materials provided to the consumer; and (E) The... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Affiliate marketing opt out... Marketing Rules § 162.3 Affiliate marketing opt out and exceptions. (a) Initial notice and opt out....

  6. 42 CFR 405.435 - Failure to maintain opt-out.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Failure to maintain opt-out. 405.435 Section 405... MEDICARE PROGRAM FEDERAL HEALTH INSURANCE FOR THE AGED AND DISABLED Private Contracts § 405.435 Failure to... meet the criteria for properly opting-out until the 2-year opt-out period expires. (c) Medicare...

  7. 40 CFR 96.83 - Applying for NOX Budget opt-in permit.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Applying for NOX Budget opt-in permit... PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO 2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.83 Applying for NOX Budget opt-in permit. (a) Applying...

  8. 40 CFR 97.83 - Applying for NOX Budget opt-in permit.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Applying for NOX Budget opt-in permit... PROGRAMS (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS Individual Unit Opt-ins. § 97.83 Applying for NOX Budget opt-in permit. (a) Applying for initial NO X Budget...

  9. 40 CFR 96.83 - Applying for NOX Budget opt-in permit.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Applying for NOX Budget opt-in permit... PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.83 Applying for NOX Budget opt-in permit. (a) Applying...

  10. 40 CFR 97.83 - Applying for NOX Budget opt-in permit.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Applying for NOX Budget opt-in permit... PROGRAMS (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS Individual Unit Opt-ins § 97.83 Applying for NOX Budget opt-in permit. (a) Applying for initial NO X Budget...

  11. 40 CFR 97.83 - Applying for NOX Budget opt-in permit.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Applying for NOX Budget opt-in permit... PROGRAMS (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS Individual Unit Opt-ins. § 97.83 Applying for NOX Budget opt-in permit. (a) Applying for initial NO X Budget...

  12. 40 CFR 96.83 - Applying for NOX Budget opt-in permit.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.83 Applying for NOX Budget opt-in permit. (a) Applying for... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Applying for NOX Budget opt-in...

  13. 40 CFR 96.88 - NOX allowance allocations to opt-in units.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.88 NOX allowance allocations to opt-in units. (a) NO X... Budget opt-in permit is effective, the permitting authority will allocate NOX allowances to the...

  14. 40 CFR 96.83 - Applying for NOX Budget opt-in permit.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.83 Applying for NOX Budget opt-in permit. (a) Applying for... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Applying for NOX Budget opt-in...

  15. 40 CFR 96.88 - NOX allowance allocations to opt-in units.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.88 NOX allowance allocations to opt-in units. (a) NO X... Budget opt-in permit is effective, the permitting authority will allocate NOX allowances to the...

  16. Assessment Opt-Out Policies: State Responses to Parent Pushback. ECS Education Trends

    ERIC Educational Resources Information Center

    Aragon, Stephanie; Rowland, Julie; Wixom, Micah Ann

    2015-01-01

    With new state assessments kicking into full swing across the country, schools are seeing more and more parents wanting to opt out their children. Determining whether states allow assessment opt-outs can be complex and is constantly evolving. In some states the answer is clear: State policies either allow or prohibit state assessment opt-outs, or…

  17. 40 CFR 88.206-94 - State opt-in for the California Pilot Test Program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 20 2014-07-01 2013-07-01 true State opt-in for the California Pilot... (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program § 88.206-94 State opt-in for the California Pilot Test Program. (a) A state may opt into the Pilot program if it...

  18. 40 CFR 88.206-94 - State opt-in for the California Pilot Test Program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 20 2011-07-01 2011-07-01 false State opt-in for the California Pilot... (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program § 88.206-94 State opt-in for the California Pilot Test Program. (a) A state may opt into the Pilot program if it...

  19. 40 CFR 88.206-94 - State opt-in for the California Pilot Test Program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 21 2012-07-01 2012-07-01 false State opt-in for the California Pilot... (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program § 88.206-94 State opt-in for the California Pilot Test Program. (a) A state may opt into the Pilot program if it...

  20. 40 CFR 88.206-94 - State opt-in for the California Pilot Test Program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 21 2013-07-01 2013-07-01 false State opt-in for the California Pilot... (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program § 88.206-94 State opt-in for the California Pilot Test Program. (a) A state may opt into the Pilot program if it...

  1. 12 CFR 573.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true Delivering privacy and opt out notices. 573.9 Section 573.9 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 573.9 Delivering privacy and opt out...

  2. 17 CFR 248.121 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Affiliate marketing opt out... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.121 Affiliate marketing opt out and exceptions. (a) Initial notice and opt out requirement—(1) In general....

  3. 12 CFR 222.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 3 2012-01-01 2012-01-01 false Affiliate marketing opt-out and exceptions. 222... FEDERAL RESERVE SYSTEM FAIR CREDIT REPORTING (REGULATION V) Affiliate Marketing § 222.21 Affiliate marketing opt-out and exceptions. (a) Initial notice and opt-out requirement—(1) In general. You may not...

  4. 12 CFR 222.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Affiliate marketing opt-out and exceptions. 222... FEDERAL RESERVE SYSTEM FAIR CREDIT REPORTING (REGULATION V) Affiliate Marketing § 222.21 Affiliate marketing opt-out and exceptions. (a) Initial notice and opt-out requirement—(1) In general. You may not...

  5. 17 CFR 248.121 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Affiliate marketing opt out... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.121 Affiliate marketing opt out and exceptions. (a) Initial notice and opt out requirement—(1) In general....

  6. 17 CFR 248.121 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Affiliate marketing opt out... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.121 Affiliate marketing opt out and exceptions. (a) Initial notice and opt out requirement—(1) In general....

  7. 16 CFR 680.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Affiliate marketing opt-out and exceptions... AFFILIATE MARKETING § 680.21 Affiliate marketing opt-out and exceptions. (a) Initial notice and opt-out... affiliate to make a solicitation for marketing purposes to the consumer, unless— (i) It is clearly...

  8. 16 CFR 680.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Affiliate marketing opt-out and exceptions... AFFILIATE MARKETING § 680.21 Affiliate marketing opt-out and exceptions. (a) Initial notice and opt-out... affiliate to make a solicitation for marketing purposes to the consumer, unless— (i) It is clearly...

  9. 17 CFR 248.121 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Affiliate marketing opt out... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.121 Affiliate marketing opt out and exceptions. (a) Initial notice and opt out requirement—(1) In general....

  10. 17 CFR 248.121 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Affiliate marketing opt out... COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing § 248.121 Affiliate marketing opt out and exceptions. (a) Initial notice and opt out requirement—(1)...

  11. 16 CFR 680.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Affiliate marketing opt-out and exceptions... AFFILIATE MARKETING § 680.21 Affiliate marketing opt-out and exceptions. (a) Initial notice and opt-out... affiliate to make a solicitation for marketing purposes to the consumer, unless— (i) It is clearly...

  12. 12 CFR 222.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 3 2014-01-01 2014-01-01 false Affiliate marketing opt-out and exceptions. 222... FEDERAL RESERVE SYSTEM (CONTINUED) FAIR CREDIT REPORTING (REGULATION V) Affiliate Marketing § 222.21 Affiliate marketing opt-out and exceptions. (a) Initial notice and opt-out requirement—(1) In general....

  13. 16 CFR 680.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Affiliate marketing opt-out and exceptions... AFFILIATE MARKETING § 680.21 Affiliate marketing opt-out and exceptions. (a) Initial notice and opt-out... affiliate to make a solicitation for marketing purposes to the consumer, unless— (i) It is clearly...

  14. 12 CFR 222.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 3 2013-01-01 2013-01-01 false Affiliate marketing opt-out and exceptions. 222... FEDERAL RESERVE SYSTEM (CONTINUED) FAIR CREDIT REPORTING (REGULATION V) Affiliate Marketing § 222.21 Affiliate marketing opt-out and exceptions. (a) Initial notice and opt-out requirement—(1) In general....

  15. 17 CFR 162.3 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Affiliate marketing opt out and exceptions. 162.3 Section 162.3 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... Affiliate Marketing Rules § 162.3 Affiliate marketing opt out and exceptions. (a) Initial notice and opt...

  16. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Contents of opt out notice; consolidated and equivalent notices. 248.123 Section 248.123 Commodity and Securities Exchanges SECURITIES AND... Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt...

  17. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Contents of opt out notice; consolidated and equivalent notices. 248.123 Section 248.123 Commodity and Securities Exchanges SECURITIES AND... Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt...

  18. 17 CFR 162.3 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Affiliate marketing opt out and exceptions. 162.3 Section 162.3 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... Marketing Rules § 162.3 Affiliate marketing opt out and exceptions. (a) Initial notice and opt out....

  19. 17 CFR 162.8 - Acceptable delivery methods of opt-out notices.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Acceptable delivery methods of opt-out notices. 162.8 Section 162.8 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... Marketing Rules § 162.8 Acceptable delivery methods of opt-out notices. (a) In general. The opt-out...

  20. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Contents of opt out notice; consolidated and equivalent notices. 248.123 Section 248.123 Commodity and Securities Exchanges SECURITIES AND... Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt...

  1. 17 CFR 162.8 - Acceptable delivery methods of opt-out notices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Acceptable delivery methods of opt-out notices. 162.8 Section 162.8 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... Marketing Rules § 162.8 Acceptable delivery methods of opt-out notices. (a) In general. The opt-out...

  2. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Contents of opt out notice; consolidated and equivalent notices. 248.123 Section 248.123 Commodity and Securities Exchanges SECURITIES AND... Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt...

  3. 75 FR 51266 - Reedsport OPT Wave Park, LLC; Notice of Settlement Agreement and Soliciting Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... Energy Regulatory Commission Reedsport OPT Wave Park, LLC; Notice of Settlement Agreement and Soliciting... No.: P-12713-002. c. Date Filed: August 2, 2010. d. Applicant: Reedsport OPT Wave Park, LLC. e... 16 U.S.C. 791 (a)-825(r). h. Applicant Contact: Dr. George Taylor, Reedsport OPT Wave Park, LLC...

  4. 75 FR 76974 - Reedsport OPT Wave Park, LLC; Oregon; Notice of Availability of Environmental Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

    ... Energy Regulatory Commission Reedsport OPT Wave Park, LLC; Oregon; Notice of Availability of... No. 486, 52 FR 47897), the Office of Energy Projects has reviewed Reedsport OPT Wave Park, LLC's application for license for the Reedsport OPT Wave Park Project (FERC Project No. 12713-002), which would...

  5. 12 CFR 41.25 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... means to opt out, such as a form that can be electronically mailed or processed at an Internet Web site... only, such as through posting at an Internet Web site, to opt out solely by paper mail or by visiting a different Web site without providing a link to that site. (c) Specific opt-out means. Each consumer may...

  6. 12 CFR 41.25 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... means to opt out, such as a form that can be electronically mailed or processed at an Internet Web site... only, such as through posting at an Internet Web site, to opt out solely by paper mail or by visiting a different Web site without providing a link to that site. (c) Specific opt-out means. Each consumer may...

  7. 12 CFR 41.25 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... means to opt out, such as a form that can be electronically mailed or processed at an Internet Web site... only, such as through posting at an Internet Web site, to opt out solely by paper mail or by visiting a different Web site without providing a link to that site. (c) Specific opt-out means. Each consumer may...

  8. In the United States, "Opt-Out" States Show No Increase in Access to Anesthesia Services for Medicare Beneficiaries Compared with Non-"Opt-Out" States.

    PubMed

    Sun, Eric C; Miller, Thomas R; Halzack, Nicholas M

    2016-05-01

    In the United States, anesthesia care can be provided by anesthesiologists or nurse anesthetists. Since 2001, 17 states have exercised their right to "opt-out" of the federal requirement that a physician supervise the administration of anesthesia by a nurse anesthetist, with the majority citing increased access to anesthesia care as the rationale for their decision. By using Medicare data, we found that most (4 of 5) cohorts of "opt-out" states likely experienced smaller growth in anesthesia utilization rates compared with non-"opt-out" states, suggesting that opt-out was not associated with an increase in access to anesthesia care.

  9. Risk Selection under Public Health Insurance with Opt-Out.

    PubMed

    Panthöfer, Sebastian

    2016-09-01

    This paper studies risk selection between public and private health insurance when some, but not all, individuals can opt out of otherwise mandatory public insurance. Using a theoretical model, I show that public insurance is adversely selected when insurers and insureds are symmetrically informed about health-related risks, and that there can be adverse or advantageous selection when insureds are privately informed. Using data from the German Socio-Economic Panel, I find that (i) public insurance is, on balance, adversely selected under the German public health insurance with opt out scheme, (ii) individuals advantageously select public insurance based on risk aversion and residential location, and (iii) there is suggestive evidence of asymmetric information in the market for private health insurance. Copyright © 2016 John Wiley & Sons, Ltd.

  10. ReOpt[trademark] V2.0 user guide

    SciTech Connect

    White, M K; Bryant, J L

    1992-10-01

    Cleaning up the large number of contaminated waste sites at Department of Energy (DOE) facilities in the US presents a large and complex problem. Each waste site poses a singular set of circumstances (different contaminants, environmental concerns, and regulations) that affect selection of an appropriate response. Pacific Northwest Laboratory (PNL) developed ReOpt to provide information about the remedial action technologies that are currently available. It is an easy-to-use personal computer program and database that contains data about these remedial technologies and auxiliary data about contaminants and regulations. ReOpt will enable engineers and planners involved in environmental restoration efforts to quickly identify potentially applicable environmental restoration technologies and access corresponding information required to select cleanup activities for DOE sites.

  11. Some Parallel Extensions to Optimization Methods in OPT++

    SciTech Connect

    V. E. Howle; S. M. Shont; P. D. Hough

    2000-10-01

    OPT++ provides an array of optimization tools for solving scientific and engineering design problems. While these tools are useful, all of the code is serial. With increasingly easy access to multiprocessor machines and clusters of workstations, this results in unnecessarily long times to solution. In order to correct this problem, we have implemented a number of parallel techniques in OPT++. In particular, we have incorporated a speculative gradient algorithm that drastically reduces the time to solution for standard trust-region and line search algorithms. In addition, we have implemented a new version of the Trust-Region Parallel Direct Search (TRPDS) algorithm of Hough and Meza that yields a significant reduction in solution time for problems with expensive function evaluations.

  12. Opt-out HIV testing in prison: informed and voluntary?

    PubMed

    Rosen, David L; Golin, Carol E; Grodensky, Catherine A; May, Jeanine; Bowling, J Michael; DeVellis, Robert F; White, Becky L; Wohl, David A

    2015-01-01

    HIV testing in prison settings has been identified as an important mechanism to detect cases among high-risk, underserved populations. Several public health organizations recommend that testing across health-care settings, including prisons, be delivered in an opt-out manner. However, implementation of opt-out testing within prisons may pose challenges in delivering testing that is informed and understood to be voluntary. In a large state prison system with a policy of voluntary opt-out HIV testing, we randomly sampled adult prisoners in each of seven intake prisons within two weeks after their opportunity to be HIV tested. We surveyed prisoners' perception of HIV testing as voluntary or mandatory and used multivariable statistical models to identify factors associated with their perception. We also linked survey responses to lab records to determine if prisoners' test status (tested or not) matched their desired and perceived test status. Thirty-eight percent (359/936) perceived testing as voluntary. The perception that testing was mandatory was positively associated with age less than 25 years (adjusted relative risk [aRR]: 1.45, 95% confidence interval [CI]: 1.24, 1.71) and preference that testing be mandatory (aRR: 1.81, 95% CI: 1.41, 2.31) but negatively associated with entry into one of the intake prisons (aRR: 0.41 95% CI: 0.27, 0.63). Eighty-nine percent of prisoners wanted to be tested, 85% were tested according to their wishes, and 82% correctly understood whether or not they were tested. Most prisoners wanted to be HIV tested and were aware that they had been tested, but less than 40% understood testing to be voluntary. Prisoners' understanding of the voluntary nature of testing varied by intake prison and by a few individual-level factors. Testing procedures should ensure that opt-out testing is informed and understood to be voluntary by prisoners and other vulnerable populations.

  13. Apple (Malus x domestica).

    PubMed

    Dandekar, Abhaya M; Teo, Gianni; Uratsu, Sandra L; Tricoli, David

    2006-01-01

    Apple (Malus x domestica) is one of the most consumed fruit crops in the world. The major production areas are the temperate regions, however, because of its excellent storage capacity it is transported to distant markets covering the four corners of the earth. Transformation is a key to sustaining this demand - permitting the potential enhancement of existing cultivars as well as to investigate the development of new cultivars resistant to pest, disease, and storage problems that occur in the major production areas. In this paper we describe an efficient Agrobacterium tumefaciens-mediated transformation protocol that utilizes leaf tissues from in vitro grown plants. Shoot regeneration is selected with kanamycin using the selectable kanamycin phosphotransferase (APH(3)II) gene and the resulting transformants confirmed using the scorable uidA gene encoding the bacterial beta-glucuronidase (GUS) enzyme via histochemical staining. Transformed shoots are propagated, rooted to create transgenic plants that are then introduced into soil, acclimatized and transferred to the greenhouse from where they are taken out into the orchard for field-testing.

  14. The APPL "Learning Map"

    NASA Technical Reports Server (NTRS)

    2005-01-01

    Root Learning, a learning consulting organization with a background in strategic planning, recognizes the knowledge gap that frequently exists between a leadership team and the rest of an organization. Team members supposedly working toward the same goal don't always have the same vision as to where the organization is headed, and they may not understand how the piece they are accountable for fits into the big picture. To address these complex problems, Root Learning utilizes the age-old tools of sarcasm, metaphor and graphics (much in the same way that ASK uses a traditional storytelling format.) The company is best known for creating "Learning Maps" like this one: humorous drawings based on the inner workings of an organization. Their purpose is to put complex topics on the table, to stimulate discussion, and to ultimately give team members a common vision of where the organization is going and what role they personally play in getting there. APPL knows how effective it is to incorporate new and engaging techniques into its knowledge sharing programs. By collaborating with Root Learning, we were able to expand the knowledge of the organization and add one more of these techniques to our repertoire.

  15. Parameter estimation uncertainty: Comparing apples and apples?

    NASA Astrophysics Data System (ADS)

    Hart, D.; Yoon, H.; McKenna, S. A.

    2012-12-01

    that M-NSMC can provide a computationally efficient and practical solution for predictive uncertainty analysis in highly nonlinear and complex subsurface flow and transport models. This material is based upon work supported as part of the Center for Frontiers of Subsurface Energy Security, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Award Number DE-SC0001114. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

  16. Cryptosporidiosis associated with ozonated apple cider.

    PubMed

    Blackburn, Brian G; Mazurek, Jacek M; Hlavsa, Michele; Park, Jean; Tillapaw, Matt; Parrish, MaryKay; Salehi, Ellen; Franks, William; Koch, Elizabeth; Smith, Forrest; Xiao, Lihua; Arrowood, Michael; Hill, Vince; da Silva, Alex; Johnston, Stephanie; Jones, Jeffrey L

    2006-04-01

    We linked an outbreak of cryptosporidiosis to ozonated apple cider by using molecular and epidemiologic methods. Because ozonation was insufficient in preventing this outbreak, its use in rendering apple cider safe for drinking is questioned.

  17. Connecting your Apple to Octopus 7600's

    SciTech Connect

    Barton, G.W. Jr.

    1983-01-17

    In UCID-19588, Communicating between the Apple and the Wang, we described how to take Apple DOS text files and send them to the Wang, and how to return Wang files to the Apple. It is also possible to use your Apple as an Octopus terminal, and to exchange files with Octopus 7600's. Presumably, you can also talk to the Crays, or any other part of the system. This connection has another virtue. It eliminates one of the terminals in your office.

  18. Loading Appleworks into the Apple IIGS Computer.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This step-by-step guide to loading AppleWorks V2.0 into the Apple IIGS computer provides instructions for energizing the computer and monitor, inserting the disk, using the Apple-control-reset function, and loading the program. Seven sample screen displays are included. (MES)

  19. What's an Adam's Apple? (For Kids)

    MedlinePlus

    ... Happens in the Operating Room? What's an Adam's Apple? KidsHealth > For Kids > What's an Adam's Apple? A A A You're at the high ... the throat. This is what's called an Adam's apple. Everyone's larynx grows during puberty, but a girl's ...

  20. Questions and Answers: Apple Juice and Arsenic

    MedlinePlus

    ... in its juice than any other company. Does organic apple juice have less arsenic than non-organic apple juice? The FDA is unaware of any ... States. Is the arsenic in apple juice predominantly organic or inorganic? Due to limited data available to ...

  1. Ensuring the genetic diversity of apples

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apples (Malus × domestica Borkh.) are a nutritious source of antioxidants, polyphenolics, vitamins, and fiber. Many of the apple cultivars that are currently produced were identified over a century ago and do not offer resistance to pathogens and tolerance to climatic threats. Apple breeding program...

  2. Recombinant DNA technology in apple.

    PubMed

    Gessler, Cesare; Patocchi, Andrea

    2007-01-01

    This review summarizes the achievements of almost 20 years of recombinant DNA technology applied to apple, grouping the research results into the sections: developing the technology, insect resistance, fungal disease resistance, self-incompatibility, herbicide resistance, fire blight resistance, fruit ripening, allergens, rooting ability, and acceptance and risk assessment. The diseases fire blight, caused by Erwinia amylovora, and scab, caused by Venturia inaequalis, were and still are the prime targets. Shelf life improvement and rooting ability of rootstocks are also relevant research areas. The tools to create genetically modified apples of added value to producers, consumers, and the environment are now available.

  3. 12 CFR 571.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Delivery of opt-out notices. 571.26 Section 571.26 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 571.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be provided so that each consumer can reasonably...

  4. 40 CFR 96.385 - CAIR opt-in permit contents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CAIR NOX Ozone Season Opt-in Units § 96.385 CAIR opt-in permit contents. (a) Each CAIR opt-in permit... Ozone Season allowances under § 96.388(b) or § 96.388(c) (subject to the conditions in §§ 96.384(h) and 96.386(g)); (6) A statement that the unit may withdraw from the CAIR NOX Ozone Season Trading...

  5. 40 CFR 96.385 - CAIR opt-in permit contents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CAIR NOX Ozone Season Opt-in Units § 96.385 CAIR opt-in permit contents. (a) Each CAIR opt-in permit... Ozone Season allowances under § 96.388(b) or § 96.388(c) (subject to the conditions in §§ 96.384(h) and 96.386(g)); (6) A statement that the unit may withdraw from the CAIR NOX Ozone Season Trading...

  6. Legal and ethical implications of opt-out HIV testing.

    PubMed

    Hanssens, Catherine

    2007-12-15

    New guidelines from the Centers for Disease Control and Prevention recommend that opt-out screening for human immunodeficiency virus (HIV) without written patient consent be part of routine clinical care and imply that state HIV-associated laws in conflict with this approach should be amended. However, HIV testing and treatment issues are governed by a range of federal and state laws, common law principles, constitutional provisions, and various codes of ethics. Patient testing protocols should satisfy the legal definition of informed consent, to reduce risk of liability for providers (i.e., health care professionals and facilities). Rigid application of the new guidelines may trigger legal claims, especially if there is no link to care for persons with a positive test result, no proof of informed consent, or inadequate counseling. Ensuring confidentiality, better test training for providers, and provider collaboration with HIV service organizations can reduce the risk of patient claims, but state and federal laws, codes of ethics, and concerns about provider liability should temper reflexive wholesale adoption of guidelines that recommend opt-out screening.

  7. Iron deficiency regulated OsOPT7 is essential for iron homeostasis in rice.

    PubMed

    Bashir, Khurram; Ishimaru, Yasuhiro; Itai, Reiko Nakanishi; Senoura, Takeshi; Takahashi, Michiko; An, Gynheung; Oikawa, Takaya; Ueda, Minoru; Sato, Aiko; Uozumi, Nobuyuki; Nakanishi, Hiromi; Nishizawa, Naoko K

    2015-05-01

    The molecular mechanism of iron (Fe) uptake and transport in plants are well-characterized; however, many components of Fe homeostasis remain unclear. We cloned iron-deficiency-regulated oligopeptide transporter 7 (OsOPT7) from rice. OsOPT7 localized to the plasma membrane and did not transport Fe(III)-DMA or Fe(II)-NA and GSH in Xenopus laevis oocytes. Furthermore OsOPT7 did not complement the growth of yeast fet3fet4 mutant. OsOPT7 was specifically upregulated in response to Fe-deficiency. Promoter GUS analysis revealed that OsOPT7 expresses in root tips, root vascular tissue and shoots as well as during seed development. Microarray analysis of OsOPT7 knockout 1 (opt7-1) revealed the upregulation of Fe-deficiency-responsive genes in plants grown under Fe-sufficient conditions, despite the high Fe and ferritin concentrations in shoot tissue indicating that Fe may not be available for physiological functions. Plants overexpressing OsOPT7 do not exhibit any phenotype and do not accumulate more Fe compared to wild type plants. These results indicate that OsOPT7 may be involved in Fe transport in rice.

  8. Is an opt-out organ donation system desirable? Comments on a new law.

    PubMed

    Petrini, C

    2016-01-01

    A law that introduces an opt-out system for organ donation has recently come into force in Wales. The debate surrounding the effectiveness and ethical acceptability of an opt-out system continues, though the available data have still not provided definitive proof that an opt-out system is more efficient than an opt-in system. Systems based on implied consent but with specific safeguards would appear more suitable and more respectful of ethical principles than those based on a more aggressive form of presumed consent.

  9. A Response to Michael W. Apple's "Theory, Research, and the Critical Scholar/Activist"

    ERIC Educational Resources Information Center

    Leonardo, Zeus

    2010-01-01

    Michael Apple's prescient review of Anyon et al.'s "Theory and Educational Research" reminds the educational community of the importance of purpose. In his own work, he has been consistent in--actually, insistent on--emphasizing the struggle over political projects. This is not an issue concerning only the Left as the scapegoat for the disparaging…

  10. Dry bin filler for apples

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A unique dry bin filler for apples using a sequenced tray was developed to reduce bruising in packing operations. Research and commercial trials in West Virginia, Pennsylvania, and Washington State demonstrated the ability to fill bins evenly and with low damage. Cultivars with different bruising su...

  11. Apple phytochemicals and their health benefits.

    PubMed

    Boyer, Jeanelle; Liu, Rui Hai

    2004-05-12

    Evidence suggests that a diet high in fruits and vegetables may decrease the risk of chronic diseases, such as cardiovascular disease and cancer, and phytochemicals including phenolics, flavonoids and carotenoids from fruits and vegetables may play a key role in reducing chronic disease risk. Apples are a widely consumed, rich source of phytochemicals, and epidemiological studies have linked the consumption of apples with reduced risk of some cancers, cardiovascular disease, asthma, and diabetes. In the laboratory, apples have been found to have very strong antioxidant activity, inhibit cancer cell proliferation, decrease lipid oxidation, and lower cholesterol. Apples contain a variety of phytochemicals, including quercetin, catechin, phloridzin and chlorogenic acid, all of which are strong antioxidants. The phytochemical composition of apples varies greatly between different varieties of apples, and there are also small changes in phytochemicals during the maturation and ripening of the fruit. Storage has little to no effect on apple phytochemicals, but processing can greatly affect apple phytochemicals. While extensive research exists, a literature review of the health benefits of apples and their phytochemicals has not been compiled to summarize this work. The purpose of this paper is to review the most recent literature regarding the health benefits of apples and their phytochemicals, phytochemical bioavailability and antioxidant behavior, and the effects of variety, ripening, storage and processing on apple phytochemicals.

  12. Apple phytochemicals and their health benefits

    PubMed Central

    Boyer, Jeanelle; Liu, Rui Hai

    2004-01-01

    Evidence suggests that a diet high in fruits and vegetables may decrease the risk of chronic diseases, such as cardiovascular disease and cancer, and phytochemicals including phenolics, flavonoids and carotenoids from fruits and vegetables may play a key role in reducing chronic disease risk. Apples are a widely consumed, rich source of phytochemicals, and epidemiological studies have linked the consumption of apples with reduced risk of some cancers, cardiovascular disease, asthma, and diabetes. In the laboratory, apples have been found to have very strong antioxidant activity, inhibit cancer cell proliferation, decrease lipid oxidation, and lower cholesterol. Apples contain a variety of phytochemicals, including quercetin, catechin, phloridzin and chlorogenic acid, all of which are strong antioxidants. The phytochemical composition of apples varies greatly between different varieties of apples, and there are also small changes in phytochemicals during the maturation and ripening of the fruit. Storage has little to no effect on apple phytochemicals, but processing can greatly affect apple phytochemicals. While extensive research exists, a literature review of the health benefits of apples and their phytochemicals has not been compiled to summarize this work. The purpose of this paper is to review the most recent literature regarding the health benefits of apples and their phytochemicals, phytochemical bioavailability and antioxidant behavior, and the effects of variety, ripening, storage and processing on apple phytochemicals. PMID:15140261

  13. Apples prevent mammary tumors in rats.

    PubMed

    Liu, Rui Hai; Liu, Jiaren; Chen, Bingqing

    2005-03-23

    Regular consumption of fruits and vegetables has been consistently shown to be associated with reduced risk of developing chronic diseases such as cancer and cardiovascular disease. Apples are commonly consumed and are the major contributors of phytochemicals in human diets. It was previously reported that apple extracts exhibit strong antioxidant and antiproliferative activities and that the major part of total antioxidant activity is from the combination of phytochemicals. Phytochemicals, including phenolics and flavonoids, are suggested to be the bioactive compounds contributing to the health benefits of apples. Here it is shown that whole apple extracts prevent mammary cancer in a rat model in a dose-dependent manner at doses comparable to human consumption of one, three, and six apples a day. This study demonstrated that whole apple extracts effectively inhibited mammary cancer growth in the rat model; thus, consumption of apples may be an effective strategy for cancer protection.

  14. Opting out against defection leads to stable coexistence with cooperation.

    PubMed

    Zhang, Bo-Yu; Fan, Song-Jia; Li, Cong; Zheng, Xiu-Deng; Bao, Jian-Zhang; Cressman, Ross; Tao, Yi

    2016-10-24

    Cooperation coexisting with defection is a common phenomenon in nature and human society. Previous studies for promoting cooperation based on kin selection, direct and indirect reciprocity, graph selection and group selection have provided conditions that cooperators outcompete defectors. However, a simple mechanism of the long-term stable coexistence of cooperation and defection is still lacking. To reveal the effect of direct reciprocity on the coexistence of cooperation and defection, we conducted a simple experiment based on the Prisoner's Dilemma (PD) game, where the basic idea behind our experiment is that all players in a PD game should prefer a cooperator as an opponent. Our experimental and theoretical results show clearly that the strategies allowing opting out against defection are able to maintain this stable coexistence.

  15. Opting out against defection leads to stable coexistence with cooperation

    PubMed Central

    Zhang, Bo-Yu; Fan, Song-Jia; Li, Cong; Zheng, Xiu-Deng; Bao, Jian-Zhang; Cressman, Ross; Tao, Yi

    2016-01-01

    Cooperation coexisting with defection is a common phenomenon in nature and human society. Previous studies for promoting cooperation based on kin selection, direct and indirect reciprocity, graph selection and group selection have provided conditions that cooperators outcompete defectors. However, a simple mechanism of the long-term stable coexistence of cooperation and defection is still lacking. To reveal the effect of direct reciprocity on the coexistence of cooperation and defection, we conducted a simple experiment based on the Prisoner’s Dilemma (PD) game, where the basic idea behind our experiment is that all players in a PD game should prefer a cooperator as an opponent. Our experimental and theoretical results show clearly that the strategies allowing opting out against defection are able to maintain this stable coexistence. PMID:27775099

  16. OptZyme: Computational Enzyme Redesign Using Transition State Analogues

    PubMed Central

    Grisewood, Matthew J.; Gifford, Nathanael P.; Pantazes, Robert J.; Li, Ye; Cirino, Patrick C.; Janik, Michael J.; Maranas, Costas D.

    2013-01-01

    OptZyme is a new computational procedure for designing improved enzymatic activity (i.e., kcat or kcat/KM) with a novel substrate. The key concept is to use transition state analogue compounds, which are known for many reactions, as proxies for the typically unknown transition state structures. Mutations that minimize the interaction energy of the enzyme with its transition state analogue, rather than with its substrate, are identified that lower the transition state formation energy barrier. Using Escherichia coli β-glucuronidase as a benchmark system, we confirm that KM correlates (R2 = 0.960) with the computed interaction energy between the enzyme and the para-nitrophenyl- β, D-glucuronide substrate, kcat/KM correlates (R2 = 0.864) with the interaction energy of the transition state analogue, 1,5-glucarolactone, and kcat correlates (R2 = 0.854) with a weighted combination of interaction energies with the substrate and transition state analogue. OptZyme is subsequently used to identify mutants with improved KM, kcat, and kcat/KM for a new substrate, para-nitrophenyl- β, D-galactoside. Differences between the three libraries reveal structural differences that underpin improving KM, kcat, or kcat/KM. Mutants predicted to enhance the activity for para-nitrophenyl- β, D-galactoside directly or indirectly create hydrogen bonds with the altered sugar ring conformation or its substituents, namely H162S, L361G, W549R, and N550S. PMID:24116038

  17. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt out...”; (iii) A general description of the types of eligibility information that may be used to make marketing... make marketing solicitations to the consumer; (v) That the consumer's election will apply for...

  18. 12 CFR 334.22 - Scope and duration of opt-out.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... POLICY FAIR CREDIT REPORTING Affiliate Marketing § 334.22 Scope and duration of opt-out. (a) Scope of opt... relationship—(i) In general. If the consumer establishes a continuing relationship with you or your affiliate... continuing relationship or multiple continuing relationships that the consumer establishes with you or...

  19. 12 CFR 41.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.23 Contents of opt-out notice; consolidated and.... (2) Joint relationships. (i) If two or more consumers jointly obtain a product or service, a single... broader right to opt out of receiving marketing than is required by this subpart, the requirements of...

  20. 16 CFR 313.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... service providers and joint marketing. 313.13 Section 313.13 Commercial Practices FEDERAL TRADE COMMISSION... Exception to opt out requirements for service providers and joint marketing. (a) General rule. (1) The opt... perform joint marketing, your contractual agreement with that institution meets the requirements...

  1. 16 CFR 313.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... service providers and joint marketing. 313.13 Section 313.13 Commercial Practices FEDERAL TRADE COMMISSION... Exception to opt out requirements for service providers and joint marketing. (a) General rule. (1) The opt... perform joint marketing, your contractual agreement with that institution meets the requirements...

  2. 16 CFR 313.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... service providers and joint marketing. 313.13 Section 313.13 Commercial Practices FEDERAL TRADE COMMISSION... Exception to opt out requirements for service providers and joint marketing. (a) General rule. (1) The opt... perform joint marketing, your contractual agreement with that institution meets the requirements...

  3. 12 CFR 717.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Delivery of opt-out notices. 717.26 Section 717.26 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS FAIR CREDIT REPORTING Affiliate Marketing § 717.26 Delivery of opt-out notices. (a) In general. The...

  4. 12 CFR 222.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Delivery of opt-out notices. 222.26 Section 222.26 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM FAIR CREDIT REPORTING (REGULATION V) Affiliate Marketing § 222.26 Delivery of opt-out notices....

  5. 12 CFR 717.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Affiliate marketing opt-out and exceptions. 717... UNIONS FAIR CREDIT REPORTING Affiliate Marketing § 717.21 Affiliate marketing opt-out and exceptions. (a... consumer that you receive from an affiliate to make a solicitation for marketing purposes to the...

  6. 12 CFR 717.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Affiliate marketing opt-out and exceptions. 717... UNIONS FAIR CREDIT REPORTING Affiliate Marketing § 717.21 Affiliate marketing opt-out and exceptions. (a... consumer that you receive from an affiliate to make a solicitation for marketing purposes to the...

  7. 12 CFR 1022.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 8 2014-01-01 2014-01-01 false Affiliate marketing opt-out and exceptions... (REGULATION V) Affiliate Marketing § 1022.21 Affiliate marketing opt-out and exceptions. (a) Initial notice... you receive from an affiliate to make a solicitation for marketing purposes to the consumer,...

  8. 12 CFR 41.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Affiliate marketing opt-out and exceptions. 41... CREDIT REPORTING Affiliate Marketing § 41.21 Affiliate marketing opt-out and exceptions. (a) Initial... consumer that it receives from an affiliate to make a solicitation for marketing purposes to the...

  9. 12 CFR 1022.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Affiliate marketing opt-out and exceptions... (REGULATION V) Affiliate Marketing § 1022.21 Affiliate marketing opt-out and exceptions. (a) Initial notice... you receive from an affiliate to make a solicitation for marketing purposes to the consumer,...

  10. 12 CFR 571.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true Affiliate marketing opt-out and exceptions. 571... CREDIT REPORTING Affiliate Marketing § 571.21 Affiliate marketing opt-out and exceptions. (a) Initial... that you receive from an affiliate to make a solicitation for marketing purposes to the...

  11. 12 CFR 41.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Affiliate marketing opt-out and exceptions. 41... CREDIT REPORTING Affiliate Marketing § 41.21 Affiliate marketing opt-out and exceptions. (a) Initial... consumer that it receives from an affiliate to make a solicitation for marketing purposes to the...

  12. 12 CFR 334.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 5 2012-01-01 2012-01-01 false Affiliate marketing opt-out and exceptions. 334... OF GENERAL POLICY FAIR CREDIT REPORTING Affiliate Marketing § 334.21 Affiliate marketing opt-out and... information about a consumer that you receive from an affiliate to make a solicitation for marketing...

  13. 12 CFR 41.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Affiliate marketing opt-out and exceptions. 41... CREDIT REPORTING Affiliate Marketing § 41.21 Affiliate marketing opt-out and exceptions. (a) Initial... consumer that it receives from an affiliate to make a solicitation for marketing purposes to the...

  14. 12 CFR 41.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Affiliate marketing opt-out and exceptions. 41... CREDIT REPORTING Affiliate Marketing § 41.21 Affiliate marketing opt-out and exceptions. (a) Initial... consumer that it receives from an affiliate to make a solicitation for marketing purposes to the...

  15. 12 CFR 1022.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Affiliate marketing opt-out and exceptions... (REGULATION V) Affiliate Marketing § 1022.21 Affiliate marketing opt-out and exceptions. (a) Initial notice... you receive from an affiliate to make a solicitation for marketing purposes to the consumer,...

  16. 12 CFR 571.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Affiliate marketing opt-out and exceptions. 571... CREDIT REPORTING Affiliate Marketing § 571.21 Affiliate marketing opt-out and exceptions. (a) Initial... that you receive from an affiliate to make a solicitation for marketing purposes to the...

  17. 12 CFR 334.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Affiliate marketing opt-out and exceptions. 334... OF GENERAL POLICY FAIR CREDIT REPORTING Affiliate Marketing § 334.21 Affiliate marketing opt-out and... information about a consumer that you receive from an affiliate to make a solicitation for marketing...

  18. 12 CFR 334.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Affiliate marketing opt-out and exceptions. 334... OF GENERAL POLICY FAIR CREDIT REPORTING Affiliate Marketing § 334.21 Affiliate marketing opt-out and... information about a consumer that you receive from an affiliate to make a solicitation for marketing...

  19. 12 CFR 334.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Affiliate marketing opt-out and exceptions. 334... OF GENERAL POLICY FAIR CREDIT REPORTING Affiliate Marketing § 334.21 Affiliate marketing opt-out and... information about a consumer that you receive from an affiliate to make a solicitation for marketing...

  20. 12 CFR 717.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Affiliate marketing opt-out and exceptions. 717... UNIONS FAIR CREDIT REPORTING Affiliate Marketing § 717.21 Affiliate marketing opt-out and exceptions. (a... consumer that you receive from an affiliate to make a solicitation for marketing purposes to the...

  1. 12 CFR 571.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 6 2012-01-01 2012-01-01 false Affiliate marketing opt-out and exceptions. 571... CREDIT REPORTING Affiliate Marketing § 571.21 Affiliate marketing opt-out and exceptions. (a) Initial... that you receive from an affiliate to make a solicitation for marketing purposes to the...

  2. 12 CFR 571.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 6 2013-01-01 2012-01-01 true Affiliate marketing opt-out and exceptions. 571... CREDIT REPORTING Affiliate Marketing § 571.21 Affiliate marketing opt-out and exceptions. (a) Initial... that you receive from an affiliate to make a solicitation for marketing purposes to the...

  3. 12 CFR 717.21 - Affiliate marketing opt-out and exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Affiliate marketing opt-out and exceptions. 717... UNIONS FAIR CREDIT REPORTING Affiliate Marketing § 717.21 Affiliate marketing opt-out and exceptions. (a... consumer that you receive from an affiliate to make a solicitation for marketing purposes to the...

  4. 40 CFR 86.1707-99 - General provisions; opt-outs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... specify an effective date for the opt-out. The effective date shall be specified in terms of the first... subpart, and specify an effective date for the opt-out. The effective date shall be specified in terms of... diagnostic system requirements specified in § 86.1717; (H) The light-duty vehicle refueling...

  5. 40 CFR 86.1705-99 - General provisions; opt-in.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... opt into the National LEV program, a motor vehicle manufacturer must submit a written opt-in... voluntary National LEV program, as set forth in 40 CFR part 86, subpart R, and agrees to be legally bound by all of the standards, requirements and other provisions of the National LEV program. XX...

  6. Opting in Between: Strategies Used by Professional Women with Children to Balance Work and Family

    ERIC Educational Resources Information Center

    Grant-Vallone, Elisa J.; Ensher, Ellen A.

    2011-01-01

    Professional women with children are inundated with conflicting messages about how to manage their careers and personal lives and whether they should "opt in" or "opt out" of the workforce. Using in-depth interviews with 23 professional women, this study focused on the career choices that women make after having children. The authors found that…

  7. 17 CFR 162.7 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Reasonable and simple methods of opting out. 162.7 Section 162.7 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... Affiliate Marketing Rules § 162.7 Reasonable and simple methods of opting out. (a) In general. A...

  8. 17 CFR 160.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Exception to opt out requirements for service providers and joint marketing. 160.13 Section 160.13 Commodity and Securities... and joint marketing. (a) General rule. (1) The opt out requirements in §§ 160.7 and 160.10 do...

  9. 12 CFR 41.22 - Scope and duration of opt-out.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Affiliate Marketing § 41.22 Scope and duration of opt-out. (a) Scope of opt-out. (1) In general. Except as... bank acts or its affiliate acts as a custodian for securities or for assets in an individual...

  10. 17 CFR 162.7 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Reasonable and simple methods of opting out. 162.7 Section 162.7 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... Marketing Rules § 162.7 Reasonable and simple methods of opting out. (a) In general. A covered...

  11. 17 CFR 162.5 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Contents of opt-out notice; consolidated and equivalent notices. 162.5 Section 162.5 Commodity and Securities Exchanges COMMODITY FUTURES... Affiliate Marketing Rules § 162.5 Contents of opt-out notice; consolidated and equivalent notices....

  12. 12 CFR 41.22 - Scope and duration of opt-out.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Affiliate Marketing § 41.22 Scope and duration of opt-out. (a) Scope of opt-out—(1) In general. Except as... bank acts or its affiliate acts as a custodian for securities or for assets in an individual...

  13. 17 CFR 162.5 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Contents of opt-out notice; consolidated and equivalent notices. 162.5 Section 162.5 Commodity and Securities Exchanges COMMODITY FUTURES... Business Affiliate Marketing Rules § 162.5 Contents of opt-out notice; consolidated and equivalent...

  14. 17 CFR 162.8 - Acceptable delivery methods of opt-out notices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Acceptable delivery methods of opt-out notices. 162.8 Section 162.8 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... Affiliate Marketing Rules § 162.8 Acceptable delivery methods of opt-out notices. (a) In general. The...

  15. 40 CFR 86.1705-99 - General provisions; opt-in.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the following language: XX COMPANY, its subsidiaries, successors and assigns hereby opts into the... effect, to be indicated with the following language: This opt-in is subject to the condition that the... pursuant to § 86.1705, to be indicated with the following language (language in brackets indicates...

  16. 40 CFR 86.1705-99 - General provisions; opt-in.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the following language: XX COMPANY, its subsidiaries, successors and assigns hereby opts into the... effect, to be indicated with the following language: This opt-in is subject to the condition that the... pursuant to § 86.1705, to be indicated with the following language (language in brackets indicates...

  17. 40 CFR 86.1707-99 - General provisions; opt-outs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... following language: XX COMPANY, its subsidiaries, successors and assigns hereby opt out of the voluntary... following language: STATE hereby opts out of the voluntary National LEV program, as set forth in 40 CFR part... state regulation of medium-duty vehicles (as defined in the California Code of Regulations, Title...

  18. 17 CFR 248.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.9 Delivering privacy and opt out notices... notice as a necessary step to obtaining a particular financial product or service; or (iv) For...

  19. 17 CFR 248.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.9 Delivering privacy and opt out notices... notice as a necessary step to obtaining a particular financial product or service; or (iv) For...

  20. 16 CFR 680.25 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... a form that can be electronically mailed or processed at an Internet Web site, if the consumer..., such as through posting at an Internet Web site, to opt out solely by paper mail or by visiting a different Web site without providing a link to that site. (c) Specific opt-out means. Each consumer may...

  1. 12 CFR 571.25 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... out, such as a form that can be electronically mailed or processed at an Internet Web site, if the..., such as through posting at an Internet Web site, to opt out solely by paper mail or by visiting a different Web site without providing a link to that site. (c) Specific opt-out means. Each consumer may...

  2. 12 CFR 334.25 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... or processed at an Internet Web site, if the consumer agrees to the electronic delivery of... receives the opt-out notice in electronic form only, such as through posting at an Internet Web site, to opt out solely by paper mail or by visiting a different Web site without providing a link to that...

  3. Association Between Apple Consumption and Physician Visits

    PubMed Central

    Davis, Matthew A.; Bynum, Julie P.W.; Sirovich, Brenda E.

    2015-01-01

    IMPORTANCE Fruit consumption is believed to have beneficial health effects, and some claim, “An apple a day keeps the doctor away.” OBJECTIVE To examine the relationship between eating an apple a day and keeping the doctor away. DESIGN, SETTING, AND PARTICIPANTS A cross-sectional study of a nationally representative sample of the noninstitutionalized US adult population. A total of 8728 adults 18 years and older from the 2007–2008 and 2009–2010 National Health and Nutrition Examination Survey completed a 24-hour dietary recall questionnaire and reported that the quantity of food they ate was reflective of their usual daily diet. EXPOSURES Daily apple eaters (consuming the equivalent of at least 1 small apple daily, or 149 g of raw apple) vs non–apple eaters, based on the reported quantity of whole apple consumed during the 24-hour dietary recall period. MAIN OUTCOMES AND MEASURES The primary outcome measure was success at “keeping the doctor away,” measured as no more than 1 visit (self-reported) to a physician during the past year; secondary outcomes included successful avoidance of other health care services (ie, no overnight hospital stays, visits to a mental health professional, or prescription medications). RESULTS Of 8399 eligible study participants who completed the dietary recall questionnaire, we identified 753 adult apple eaters (9.0%)—those who typically consume at least 1 small apple per day. Compared with the 7646 non–apple eaters (91.0%), apple eaters had higher educational attainment, were more likely to be from a racial or ethnic minority, and were less likely to smoke (P < .001 for each comparison). Apple eaters were more likely, in the crude analysis, to keep the doctor (and prescription medications) away: 39.0% of apple eaters avoided physician visits vs 33.9%of non–apple eaters (P = .03). After adjusting for sociodemographic and health-related characteristics, however, the association was no longer statistically significant

  4. Mercury residues in south Florida apple snails (Pomacea paludosa)

    SciTech Connect

    Eisemann, J.D.; Beyer, W.N.; Morton, A.; Bennetts, R.E.

    1997-05-01

    Mercury concentrations in the sediments of south Florida wetlands have increased three fold in the last century. Because south Florida is home to many endemic and endangered species, it is important to understand the potential impacts of mercury in this ecosystem`s food web. Recent research by Malley et al. has shown mollusks to be sensitive indicators of methyl mercury which can reflect small differences in background methyl mercury concentrations. In this study, we attempted to determine if the apple snail (Pomacea paludosa) or its eggs are good indicators of bioavailable mercury. Then, using the apple snail as an indicator, we attempted to determine geographic differences in the concentrations of mercury in south Florida. 12 refs., 1 fig., 1 tab.

  5. Occurrence of Apple stem grooving virus in commercial apple seedlings and analysis of its coat protein sequence

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Virus infections are responsible for reduced yield and quality in many crops, and are especially problematic in vegetatively-propagated crops such as apple. Three major viruses (Apple stem grooving virus (ASGV), Apple chlorotic leaf spot virus and Apple stem pitting virus) affect apple trees in Kore...

  6. Apple cuticle: the perfect interface

    NASA Astrophysics Data System (ADS)

    Curry, Eric; Arey, Bruce

    2010-06-01

    The domestic apple might well be called an 'extreme' fruit. In the arid Northwest United States, the fruit often tolerates surface temperatures ranging from -2 °C in the early spring to 50 °C in the heat of summer, and again to -2 °C during controlled postharvest storage for up to 12 months. During its 18-month existence, the apple maintains a cuticle that is dynamic and environmentally responsive to protect against 1) cellular water loss during desiccation stress and 2) excessive uptake of standing surface moisture. Physiological disorders of the peel such as russeting, cracking, splitting, flecking and lenticel marking, develop as epidermal cells respond to rapid changes in ambient conditions at specific developmental stages during the growing season. Resultant market losses underlie research investigating the nature of apple cuticle growth and development. Ultrastructural analysis of the pro-cuticle using scanning electron microscopy indicates an overlapping network of lipid-based distally-elongating microtubules--produced by and connected to epidermal cells--which co-polymerize to form an organic solvent-insoluble semi-permeable cutin matrix. Microtubule elongation, aggregation, and polymerization function together as long as the fruit continues to enlarge. The nature of lipid transport from the epidermal cells through the cell wall to become part of the cuticular matrix was explored using an FEI Helios NanoLabTM DualBeamTM focused ion beam/scanning electron microscope on chemically- and cryo-fixed peel tissue from mature or freshly harvested apples. Based on microtubule dimensions, regular projections found at the cell/cuticle interface suggest an array of microtubule-like structures associated with the epidermal cell.

  7. Orienting apples for imaging using their inertial properties and random apple loading

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The inability to control apple orientation during imaging has hindered development of automated systems for sorting apples for defects such as bruises and for safety issues such as fecal contamination. Recently, a potential method for orienting apples based on their inertial properties was discovere...

  8. The OptIC Data Assimilation Intercomparison: A Statistical Critique

    NASA Astrophysics Data System (ADS)

    Enting, I. G.; Clisby, N.

    2008-12-01

    The development of improved terrestrial carbon models has assumed great importance because of concerns about significant climate-to-carbon feedback processes. The complexity of the interactions leads to considerable difficulties in the process of model calibration. The OptIC intercomparison explored some aspects of model calibration, using an idealised terrestrial carbon model. Participants were invited to estimate model parameters in various cases defined by specified time series of the model state, with various forms of added noise. The study identified the crucial importance of the choice of cost function. The present analysis revisits the OptIC study, by considering it as an exercise in statistical estimation. This treats the observations as random variables. Consequently parameter estimates, â, based on observations will also be random variables whose distribution is known as the 'sampling distribution'. Key questions for any specific case are: Are departures from â/a_true =1 indication of bias or sampling error? Under what circumstance are uncertainty estimates (of Var[â]) reliable? We consider cases where the estimate is obtained by minimising a cost function, ΘX. Assuming that we know the true form of ℓ, the log likelihood, there are three different characterisations of uncertainty that should be distinguished: (i) The uncertainty from maximum-likelihood estimates, corresponding (either exactly or asymptotically) to the Cramer-Rao bound. In a realistic calibration situation, we won't be able to determine this because the 'true' form of the likelihood is unknown. (ii) The actual uncertainty associated with using a particular cost function. If the true noise distribution is known, this can be calculated in simple cases and determined from simulations in more complicated cases. (iii) The 'formal uncertainty' based on assuming (usually incorrectly) that ΘX is the true likelihood. In the first stage of the analysis, the distinctions are illustrated by

  9. Preference for physician vs. nurse-initiated opt-out screening on HIV test acceptance.

    PubMed

    Kinsler, Janni J; Sayles, Jennifer N; Cunningham, William E; Mahajan, Anish

    2013-01-01

    Provider-initiated opt-out HIV screening suggests that providers should routinely order HIV tests unless a patient declines. However, data on how providers will respond to this new screening model are scarce. Documented concerns from the providers' perspectives have included time constraints of a typical patient encounter, and discomfort with discussing sexual history and risk behavior with patients. To address these potential barriers, nurse-initiated screening has been proposed as an approach to increasing screening rates in general medical and urgent care settings. This study compares patient acceptability of provider-initiated opt-out HIV screening with nurse-initiated opt-out HIV screening among 220 patients between the ages of 18-64 from two publically funded "safety-net" outpatient clinics in Los Angeles County. Our study found that 77% of patients agreed to HIV testing using opt-out screening, and that HIV test acceptance was higher with the physician-initiated opt-out model compared with the nurse-initiated opt-out model (adjusted odds ratios = 2.92; 95% CI = 1.37-6.22). These findings indicate that adding opt-out screening to primary care providers responsibilities may be an acceptable and effective strategy for addressing the perennially low HIV testing rates, particularly among low income, traditionally underserved patient populations among whom the epidemic is expanding most rapidly.

  10. Historic American apple cultivars: Identification and availability

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apples have been important throughout the centuries in North America. Historic books, publications, and nursery catalogs were surveyed to identify apple cultivars that were propagated and grown in the United States prior to 1908. We collected synonym, introduction date, and original source country i...

  11. Unique characteristics of Geneva apple rootstocks

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Geneva® apple rootstock breeding program has been operating since the early 1970’s. It is a unique program in that it had access to important germplasm resources that later became the USDA ARS apple collection in Geneva, NY. This genetic diversity allowed for the achievement of one of the proj...

  12. Production of alcohol from apple pomace

    SciTech Connect

    Hang, Y.D.; Lee, C.Y.; Woodams, E.E.; Cooley, H.J.

    1981-12-01

    Production of ethyl alcohol from apple pomace with a Montrachet strain of Saccharomyces cerevisiae is described. More than 43 grams of the ethyl alcohol could be produced per kg of apple pomace fermented at 30 degrees Celcius in 24 hours. The fermentation efficiency of this process was approximately 89%. (Refs. 9).

  13. 9,250 Apples for the Teacher.

    ERIC Educational Resources Information Center

    Uston, Ken

    1983-01-01

    Discusses Apple Computer Inc.'s plan to donate an Apple IIe to eligible elementary/secondary schools in California, dealer incentives for conducting orientation sessions for school personnel, and school uses of the computer (including peer tutoring and teacher education). Also discusses similar efforts of other microcomputer manufacturers. (JN)

  14. SED/Apple Computer, Inc., Partnership Program.

    ERIC Educational Resources Information Center

    Stoll, Peter F.

    1991-01-01

    In 1990, the New York State Education Department (SED), Apple Computer, Inc., Boards of Cooperative Educational Services (BOCES), and school districts formed a partnership to explore the contribution technology can make to schools based on Apple Computer's Learning Society and SED's Long-Range Plan for Technology in Elementary and Secondary…

  15. [Toxicity and apple production in southern Brazil].

    PubMed

    Klanovicz, Jó

    2010-03-01

    The article explores the links between the controversial apprehension of contaminated apples in southern Brazil in 1989 and the reactions of the apple industry to press reports on the use of pesticides in Brazilian orchards. The issue is framed within a broader analysis of the notions of toxicity and 'danger' surrounding the consumption of healthier food and the idea of 'food security,' notions that have begun taking hold in public and private life. It is argued that apple growers' responses to the problem can be better understood through a historical reading of the interactions between the biology of the apple tree, the agroecology of this monoculture, and the structures, actors, and discourses of the human and non-human groups in Brazil's apple-producing region.

  16. Opt-Out and Opt-In Testing Increases Syphilis Screening of HIV-Positive Men Who Have Sex with Men in Australia

    PubMed Central

    Guy, Rebecca; El-Hayek, Carol; Fairley, Christopher K.; Wand, Handan; Carr, Andrew; McNulty, Anna; Hoy, Jenny; Bourne, Christopher; McAllister, John; Tee, B. K.; Baker, David; Roth, Norman; Stoove, Mark; Chen, Marcus

    2013-01-01

    Background Since 2005, Australian clinicians were advised to undertake quarterly syphilis testing for all sexually active HIV-positive men who have sex with men (MSM). We describe differences in syphilis testing frequency among HIV-positive MSM by clinic testing policies since this recommendation. Methods Three general practices, two sexual health clinics and two hospital HIV outpatient clinics provided data on HIV viral load and syphilis testing from 2006–2010. Men having ≥1 viral load test per year were included; >95% were MSM. We used Chi-2 tests to assess changes in syphilis testing frequency over time, and differences by clinic testing policy (opt-out, opt-in and risk-based). Results The proportion of men having HIV viral loads with same-day syphilis tests increased from 37% in 2006 to 63% in 2007 (p<0.01) and 68–69% thereafter. In 2010, same-day syphilis testing was highest in four clinics with opt-out strategies (87%, range:84–91%) compared with one clinic with opt-in (74%, p = 0.121) and two clinics with risk-based strategies (22%, range:20–24%, p<0.01). The proportion of men having ≥3 syphilis tests per year increased from 15% in 2006 to 36% in 2007 (p<0.01) and 36–38% thereafter. In 2010, the proportion of men having ≥3 syphilis tests in a year was highest in clinics with opt-out strategies (48%, range:35–59%), compared with opt-in (39%, p = 0.121) and risk-based strategies (8.4%, range:5.4–12%, p<0.01). Conclusion Over five years the proportion of HIV-positive men undergoing syphilis testing at recommended frequencies more than doubled, and was 5–6 times higher in clinics with opt-out and opt-in strategies compared with risk-based policies. PMID:24009661

  17. 40 CFR 96.188 - CAIR NOX allowance allocations to CAIR NOX opt-in units.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) AIR PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR NOX Opt-in Units § 96.188 CAIR NOX allowance allocations to CAIR NOX...

  18. 40 CFR 96.188 - CAIR NOX allowance allocations to CAIR NOX opt-in units.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) AIR PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR NOX Opt-in Units § 96.188 CAIR NOX allowance allocations to CAIR NOX...

  19. 12 CFR 222.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SYSTEM FAIR CREDIT REPORTING (REGULATION V) Affiliate Marketing § 222.26 Delivery of opt-out notices. (a... of the Electronic Signatures in Global and National Commerce Act, 15 U.S.C. 7001 et seq. (b)...

  20. 12 CFR 334.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... POLICY FAIR CREDIT REPORTING Affiliate Marketing § 334.26 Delivery of opt-out notices. (a) In general... Electronic Signatures in Global and National Commerce Act, 15 U.S.C. 7001 et seq. (b) Examples of...

  1. Reduced rate brassica seed meal amendment efficacy is apple rootstock genotype-dependent

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Brassica seed meal formulations have been shown to provide effect control of the biologically complex disease phenomenon termed apple replant disease (Mazzola et al., 2015). The seed meal formulation when used at an application rate of 3 ton ac-1 provided disease control that was in some instances ...

  2. 42 CFR 405.425 - Effects of opting-out of Medicare.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Effects of opting-out of Medicare. 405.425 Section 405.425 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM FEDERAL HEALTH INSURANCE FOR THE AGED AND DISABLED Private Contracts § 405.425 Effects of opting-out of Medicare. If a...

  3. Susceptibility of fruit from diverse apple and crabapple germplasm to attack from apple maggot (Diptera: Tephritidae).

    PubMed

    Myers, Clayton T; Reissig, W Harvey; Forsline, Phillip L

    2008-02-01

    Apple maggot, Rhagoletis pomonella (Walsh) (Diptera: Tephritidae), is a pest of major concern to apple, Malus x domestica (Borkh.) production in eastern North America. Host plant resistance to apple maggot among apple germplasm has been previously evaluated among a small number of exotic Malus accessions and domestic hybrid selections. However, a large number of exotic accessions housed in USDA collections have never been evaluated for their susceptibility to apple pests. Additionally, previous reports of resistance need to be confirmed under both field conditions and with more rigorous laboratory evaluations. Thus, studies were conducted to evaluate the susceptibility of a number of Malus accessions housed at the USDA Plant Genetic Resources Unit "core" collection. Contrary to earlier published reports, these results suggest that some selections previously described as "resistant" are in fact susceptible to both oviposition damage and larval feeding damage by apple maggot. One domestic, disease-resistant apple accession, 'E36-7' is resistant to survival of apple maggot larvae except when the fruit is nearly ripe in late fall. This is the first report of an apple cultivar that is confirmed to be resistant to larval feeding of apple maggot. Although adults can successfully oviposit on all accessions examined, larval survival was zero in a number of small-fruited crabapple accessions classified as resistant in previous studies and also in two accessions, Malus tschonoskii (Maxim) C. K. Schneid. and M. spectabilis (Aiton) Borkh., that have not been previously evaluated.

  4. A Genetic Algorithm with the Improved 2-opt Method for Quadratic Assignment Problem

    NASA Astrophysics Data System (ADS)

    Matayoshi, Mitsukuni; Nakamura, Morikazu; Miyagi, Hayao

    We propose a new 2-opt base method as a local search approach used with Genetic Algorithms (GAs) in Memetic Algorithm. We got a hint from the fast 2-opt method and devised the new 2-opt method. The main different point is such that our method exchanges genes by using histories of contributions to fitness value improvement. The contribution level is represented by the value `Priority’. In computer experiment, Quadratic Assignment Problem (QAP) instances are solved by GA with the 2-opt method(First Admissible Move Strategy, the Best Admissible Move Strategy), the fast 2-opt, and our proposed method for comparative evaluation. The results showed that our improved method obtained better solutions at ealier generation of the GA and our method required less computation time than the others at some upper bound value of appropriate `Priority’ setting values. Specially, at the average elapsed time of the fast 2-opt method’s 1000th generation, the exact solution findings of ours is more than the others. In further experiment, we observe that the searching capability depends on the number of levels of `Priority’. The ratio between two different Priority level sets becomes 1.59 in computation time in solving problem instance “char25a". This characteristic is shown to be statistically significant in ten instances among eleven.

  5. 7 CFR 33.50 - Apples for processing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Apples for processing. 33.50 Section 33.50 Agriculture... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Interpretive Rules § 33.50 Apples for processing. The terms “apples for processing” as used in § 33.12 of this part apply only and is restricted to...

  6. 7 CFR 33.50 - Apples for processing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Apples for processing. 33.50 Section 33.50 Agriculture... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Interpretive Rules § 33.50 Apples for processing. The terms “apples for processing” as used in § 33.12 of this part apply only and is restricted to...

  7. 7 CFR 33.50 - Apples for processing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 2 2012-01-01 2012-01-01 false Apples for processing. 33.50 Section 33.50 Agriculture... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Interpretive Rules § 33.50 Apples for processing. The terms “apples for processing” as used in § 33.12 of this part apply only and is restricted to...

  8. 7 CFR 33.50 - Apples for processing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false Apples for processing. 33.50 Section 33.50 Agriculture... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Interpretive Rules § 33.50 Apples for processing. The terms “apples for processing” as used in § 33.12 of this part apply only and is restricted to...

  9. 7 CFR 33.50 - Apples for processing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Apples for processing. 33.50 Section 33.50 Agriculture... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Interpretive Rules § 33.50 Apples for processing. The terms “apples for processing” as used in § 33.12 of this part apply only and is restricted to...

  10. Susceptibility of fruit from diverse apple and crabapple germplasm to attack from apple maggot, Rhagoletis pomonella (Walsh) (Diptera: Tephritidae)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apple maggot, Rhagoletis pomonella (Walsh) is a pest of major concern to apple, Malus x domestica (Borkh.) production in eastern North America. Host-plant resistance to apple maggot among apple germplasm has been previously evaluated among a small number of exotic Malus accessions and domestic hyb...

  11. Evaluation of Reference Genes for the Relative Quantification of Apple stem grooving virus and Apple mosaic virus in Apple Trees.

    PubMed

    Gadiou, S; Kundu, J K

    2012-06-01

    A SYBR Green(®)-based one step RT-qPCR assay was developed for the detection and quantification of Apple stem grooving virus (ASGV) and Apple mosaic virus (ApMV). The RT-qPCR assay employed seven plant-expressed genes-glyceraldehyde 3-phosphate dehydrogenase (GAPDH), 18S ribosomal RNA, ubiquitin, ribosomal protein S19, Rubisco, RNA polymerase subunit II and β-actin-as internal reference housekeeping genes in a relative quantification system in three apple cultivars (i.e. Idared, Champion, Fragrance). The average expression stability (M) found by GeNorm software suggest that GAPDH and S19 were the most stable reference genes. We propose employing GAPDH and S19 as housekeeping genes for accurate quantification of ASGV and ApMV in apple leaf samples. The detection limit for both viruses was found around 70 copies of viral genome by one-step RT-qPCR.

  12. ICP-AES determination of minor- and major elements in apples after microwave assisted digestion.

    PubMed

    Juranović Cindrić, Iva; Krizman, Ivona; Zeiner, Michaela; Kampić, Štefica; Medunić, Gordana; Stingeder, Gerhard

    2012-12-15

    The aim of this paper was to determine the content of minor and major elements in apples by inductively coupled plasma atomic emission spectrometry (ICP-AES). Prior to ICP-AES measurement, dried apples were digested in a microwave assisted digestion system. The differences in the measured element concentrations after application of open and closed microwave system as sample preparation procedures are discussed. In whole apples, flesh and peel Ag, Al, Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, Pb, Sr and Zn were analysed after optimisation and validating the analytical method using ICP-AES. The accuracy of the method determined by spiking experiments was very good (recoveries 88-115%) and the limits of detection of elements of interest were from 0.01 up to 14.7 μg g(-1). The reference ranges determined in all apple samples are 39-47 mg g(-1) for K, 9-14 mg g(-1) for Na, 3-7 mg g(-1) for Mg, 3-7 μg g(-1) for Zn, 0.7-2.8 μg g(-1) for Sr. The range of Mn in peel 4-6 μg g(-1) is higher compared to whole apple from 0.7 to 1.7 μg g(-1). Cd is found only in peel, in the concentration range of 0.4-1.1 μg g(-1).

  13. Goldstone Apple Valley Radio Telescope Project.

    ERIC Educational Resources Information Center

    Ibe, Mary; MacLaren, Dave

    2003-01-01

    Describes the Goldstone Apple Valley Radio Telescope (GAVRT) project as a way of teaching astronomy concepts to middle school students. The project provides students opportunities to work with professional scientists. (SOE)

  14. Biochemistry of Apple Aroma: A Review.

    PubMed

    Espino-Díaz, Miguel; Sepúlveda, David Roberto; González-Aguilar, Gustavo; Olivas, Guadalupe I

    2016-12-01

    Flavour is a key quality attribute of apples defined by volatile aroma compounds. Biosynthesis of aroma compounds involves metabolic pathways in which the main precursors are fatty and amino acids, and the main products are aldehydes, alcohols and esters. Some enzymes are crucial in the production of volatile compounds, such as lipoxygenase, alcohol dehydrogenase, and alcohol acyltransferase. Composition and concentration of volatiles in apples may be altered by pre- and postharvest factors that cause a decline in apple flavour. Addition of biosynthetic precursors of volatile compounds may be a strategy to promote aroma production in apples. The present manuscript compiles information regarding the biosynthesis of volatile aroma compounds, including metabolic pathways, enzymes and substrates involved, factors that may affect their production and also includes a wide number of studies focused on the addition of biosynthetic precursors in their production.

  15. Biochemistry of Apple Aroma: A Review

    PubMed Central

    Espino-Díaz, Miguel; Sepúlveda, David Roberto; González-Aguilar, Gustavo

    2016-01-01

    Summary Flavour is a key quality attribute of apples defined by volatile aroma compounds. Biosynthesis of aroma compounds involves metabolic pathways in which the main precursors are fatty and amino acids, and the main products are aldehydes, alcohols and esters. Some enzymes are crucial in the production of volatile compounds, such as lipoxygenase, alcohol dehydrogenase, and alcohol acyltransferase. Composition and concentration of volatiles in apples may be altered by pre- and postharvest factors that cause a decline in apple flavour. Addition of biosynthetic precursors of volatile compounds may be a strategy to promote aroma production in apples. The present manuscript compiles information regarding the biosynthesis of volatile aroma compounds, including metabolic pathways, enzymes and substrates involved, factors that may affect their production and also includes a wide number of studies focused on the addition of biosynthetic precursors in their production. PMID:28115895

  16. Ergonomic evaluation of the Apple Adjustable Keyboard

    SciTech Connect

    Tittiranonda, P.; Burastero, S.; Shih, M.; Rempel, D.

    1994-05-01

    This study presents an evaluation of the Apple Adjustable Keyboard based on subjective preference and observed joint angles during typing. Thirty five keyboard users were asked to use the Apple adjustable keyboard for 7--14 days and rate the various characteristics of the keyboard. Our findings suggest that the most preferred opening angles range from 11--20{degree}. The mean ulnar deviation on the Apple Adjustable keyboard is 11{degree}, compared to 16{degree} on the standard keyboard. The mean extension was decreased from 24{degree} to 16{degree} when using the adjustable keyboard. When asked to subjectively rate the adjustable keyboard in comparison to the standard, the average subject felt that the Apple Adjustable Keyboard was more comfortable and easier to use than the standard flat keyboard.

  17. Production of apple snail for space diet

    NASA Astrophysics Data System (ADS)

    Yamashita, Masamichi; Motoki, Shigeru; Space Agriculture Task Force, J.; Katayama, Naomi

    For food production in space at recycling bio-elements under closed environment, appropriate organisms should be chosen to drive the closed materials recycle loop. We propose a combination of green algae, photosynthetic protozoa, and aquatic plants such as Wolffia spp., for the primary producer fixing solar energy to chemical form in biomass, and apple snail, Pomacea bridgesii, which converts this biomass to animal meat. Because of high proliferation rate of green algae or protozoa compared to higher plants, and direct conversion of them to apple snail, the efficiency of food production in this combination is high, in terms of energy usage, space for rearing, and yield of edible biomass. Furthermore, green algae and apple snail can form a closed ecological system with exchanging bio-elements between two member, i.e. excreta of snail turn to fertilizer of algae, and grown algae become feed for snail. Since apple snail stays in water or on wet substrate, control of rearing is easy to make. Mass production technology of apple snail has been well established to utilize it as human food. Nutrients of apple snail are also listed in the standard tables of food composition in Japan. Nutrients for 100 g of apple snail canned in brine are energy 340 kJ, protein 16.5 g, lipid 1.0 g, cholesterol 240 mg, carbohydrate 0.8 g, Ca 400 mg, Fe 3.9 mg, Zn 1.5 mg. It is rich in minerals, especially Ca and Fe. Vitamin contents are quite low, but K 0.005 mg, B2 0.09 mg, B12 0.0006 mg, folate 0.001 mg, and E 0.6 mg. The amino acid score of apple snail could not be found in literature. Overall, apple snail provides rich protein and animal lipid such as cholesterol. It could be a good source of minerals. However, it does not give enough vitamin D and B12 , which are supposed to be supplemented by animal origin foods. In terms of acceptance in food culture, escargot is a gourmet menu in French dishes, and six to ten snail, roughly 50 g, are served for one person. Apple snail reaches to 30 g

  18. Apple quality, storage, and washing treatments affect patulin levels in apple cider.

    PubMed

    Jackson, Lauren S; Beacham-Bowden, Tina; Keller, Susanne E; Adhikari, Chaitali; Taylor, Kirk T; Chirtel, Stewart J; Merker, Robert I

    2003-04-01

    Patulin is a mycotoxin produced primarily by Penicillium expansum, a mold responsible for rot in apples and other fruits. The growth of this fungus and the production of patulin are common in fruit that has been damaged. However, patulin can be detected in visibly sound fruit. The purpose of this project was to determine how apple quality, storage, and washing treatments affect patulin levels in apple cider. Patulin was not detected in cider pressed from fresh tree-picked apples (seven cultivars) but was found at levels of 40.2 to 374 microg/liter in cider pressed from four cultivars of fresh ground-harvested (dropped) apples. Patulin was not detected in cider pressed from culled tree-picked apples stored for 4 to 6 weeks at 0 to 2 degrees C but was found at levels of 0.97 to 64.0 microg/liter in cider pressed from unculled fruit stored under the same conditions. Cider from controlled-atmosphere-stored apples that were culled before pressing contained 0 to 15.1 microg of patulin per liter, while cider made from unculled fruit contained 59.9 to 120.5 microg of patulin per liter. The washing of ground-harvested apples before pressing reduced patulin levels in cider by 10 to 100%, depending on the initial patulin levels and the type of wash solution used. These results indicate that patulin is a good indicator of the quality of the apples used to manufacture cider. The avoidance of ground-harvested apples and the careful culling of apples before pressing are good methods for reducing patulin levels in cider.

  19. Search area Expanding Strategy and Dynamic Priority Setting Method in the Improved 2-opt Method

    NASA Astrophysics Data System (ADS)

    Matayoshi, Mitsukuni; Nakamura, Morikazu; Miyagi, Hayao

    We propose a new 2-opt base method in a Memetic algorithm, that is, Genetic Algorithms(GAs) with a local search. The basic idea is from the fast 2-opt(1) method and the improved 2-opt method(20). Our new search method uses the “Priority" employed in the improved 2-opt method. The “Priority" represents the contribution level in exchange of genes. Matayoshi's method exchanges genes based on previous contribution to the fitness value improvement. We propose a new search method by using the concept of the Priority. We call our method the search area expanding strategy method in the improved 2-opt method. Our method escalates the search area by using “Priority". In computer experiment, it is shown that the computation time to find exact solution depends on the value of the Priority. If our method does not set an appropriate priority beforehand, then we propose the method to adapt to suitable value. If improvement does not achieved for certain generations, our dynamic priority method tries to modify the priority by the mutation operation. Experimental results show that the search area expanding strategy method embedded with the dynamic priority setting method can find the exact solution at earlier generation than other methods for comparison.

  20. Opt2 mediates the exposure of phospholipids during cellular adaptation to altered lipid asymmetry.

    PubMed

    Yamauchi, Saori; Obara, Keisuke; Uchibori, Kenya; Kamimura, Akiko; Azumi, Kaoru; Kihara, Akio

    2015-01-01

    Plasma membrane lipid asymmetry is important for various membrane-associated functions and is regulated by membrane proteins termed flippases and floppases. The Rim101 pathway senses altered lipid asymmetry in the yeast plasma membrane. The mutant lem3Δ cells, in which lipid asymmetry is disturbed owing to the inactivation of the plasma membrane flippases, showed a severe growth defect when the Rim101 pathway was impaired. To identify factors involved in the Rim101-pathway-dependent adaptation to altered lipid asymmetry, we performed DNA microarray analysis and found that Opt2 induced by the Rim101 pathway plays an important role in the adaptation to altered lipid asymmetry. Biochemical investigation of Opt2 revealed its localization to the plasma membrane and the Golgi, and provided several lines of evidence for the Opt2-mediated exposure of phospholipids. In addition, Opt2 was found to be required for the maintenance of vacuolar morphology and polarized cell growth. These results suggest that Opt2 is a novel factor involved in cell homeostasis by regulating lipid asymmetry.

  1. SPECT-OPT multimodal imaging enables accurate evaluation of radiotracers for β-cell mass assessments

    PubMed Central

    Eter, Wael A.; Parween, Saba; Joosten, Lieke; Frielink, Cathelijne; Eriksson, Maria; Brom, Maarten; Ahlgren, Ulf; Gotthardt, Martin

    2016-01-01

    Single Photon Emission Computed Tomography (SPECT) has become a promising experimental approach to monitor changes in β-cell mass (BCM) during diabetes progression. SPECT imaging of pancreatic islets is most commonly cross-validated by stereological analysis of histological pancreatic sections after insulin staining. Typically, stereological methods do not accurately determine the total β-cell volume, which is inconvenient when correlating total pancreatic tracer uptake with BCM. Alternative methods are therefore warranted to cross-validate β-cell imaging using radiotracers. In this study, we introduce multimodal SPECT - optical projection tomography (OPT) imaging as an accurate approach to cross-validate radionuclide-based imaging of β-cells. Uptake of a promising radiotracer for β-cell imaging by SPECT, 111In-exendin-3, was measured by ex vivo-SPECT and cross evaluated by 3D quantitative OPT imaging as well as with histology within healthy and alloxan-treated Brown Norway rat pancreata. SPECT signal was in excellent linear correlation with OPT data as compared to histology. While histological determination of islet spatial distribution was challenging, SPECT and OPT revealed similar distribution patterns of 111In-exendin-3 and insulin positive β-cell volumes between different pancreatic lobes, both visually and quantitatively. We propose ex vivo SPECT-OPT multimodal imaging as a highly accurate strategy for validating the performance of β-cell radiotracers. PMID:27080529

  2. SPECT-OPT multimodal imaging enables accurate evaluation of radiotracers for β-cell mass assessments.

    PubMed

    Eter, Wael A; Parween, Saba; Joosten, Lieke; Frielink, Cathelijne; Eriksson, Maria; Brom, Maarten; Ahlgren, Ulf; Gotthardt, Martin

    2016-04-15

    Single Photon Emission Computed Tomography (SPECT) has become a promising experimental approach to monitor changes in β-cell mass (BCM) during diabetes progression. SPECT imaging of pancreatic islets is most commonly cross-validated by stereological analysis of histological pancreatic sections after insulin staining. Typically, stereological methods do not accurately determine the total β-cell volume, which is inconvenient when correlating total pancreatic tracer uptake with BCM. Alternative methods are therefore warranted to cross-validate β-cell imaging using radiotracers. In this study, we introduce multimodal SPECT - optical projection tomography (OPT) imaging as an accurate approach to cross-validate radionuclide-based imaging of β-cells. Uptake of a promising radiotracer for β-cell imaging by SPECT, (111)In-exendin-3, was measured by ex vivo-SPECT and cross evaluated by 3D quantitative OPT imaging as well as with histology within healthy and alloxan-treated Brown Norway rat pancreata. SPECT signal was in excellent linear correlation with OPT data as compared to histology. While histological determination of islet spatial distribution was challenging, SPECT and OPT revealed similar distribution patterns of (111)In-exendin-3 and insulin positive β-cell volumes between different pancreatic lobes, both visually and quantitatively. We propose ex vivo SPECT-OPT multimodal imaging as a highly accurate strategy for validating the performance of β-cell radiotracers.

  3. Comment on "Temperature dependence of atomic vibrations in mono-layer graphene" [J. Appl. Phys. 118, 074302 (2015)

    NASA Astrophysics Data System (ADS)

    Susi, T.; Kotakoski, J.

    2016-02-01

    In an interesting recent study [Allen et al., J. Appl. Phys. 118, 074302 (2015)] (see also their Erratum [Allen et al., J. Appl. Phys. 118, 159902 (2015)]), Allen and co-workers measured the mean square amplitudes of graphene lattice vibrations between 100 and 1300 K and used a simplified theoretical approximation for the acoustic phonon modes to evaluate the maximum phonon wavelengths supported by the lattice. By fitting their data using the smallest wave-vector as the fitting parameter, they found this to be significantly smaller than the physical size of the graphene crystallites.

  4. Comment on “Temperature dependence of atomic vibrations in mono-layer graphene” [J. Appl. Phys. 118, 074302 (2015)

    SciTech Connect

    Susi, T. Kotakoski, J.

    2016-02-14

    In an interesting recent study [Allen et al., J. Appl. Phys. 118, 074302 (2015)] (see also their Erratum [Allen et al., J. Appl. Phys. 118, 159902 (2015)]), Allen and co-workers measured the mean square amplitudes of graphene lattice vibrations between 100 and 1300 K and used a simplified theoretical approximation for the acoustic phonon modes to evaluate the maximum phonon wavelengths supported by the lattice. By fitting their data using the smallest wave-vector as the fitting parameter, they found this to be significantly smaller than the physical size of the graphene crystallites.

  5. Survey of apple chlorotic leaf spot virus and apple stem grooving virus occurrence in Korea and frequency of mixed infections in apple

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Due to the absence of knowledge of the distribution of Apple stem grooving virus (ASGV) and Apple chlorotic leaf spot virus (ACLSV) in apples in Korea, we carried out a survey for these viruses in Gyeongsang and Chungcheong provinces in 2014. A total of 65 samples were collected and tested by RT-PCR...

  6. Constructing AppleWorks Word Processing Files for the Apple IIe Computer.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This step-by-step guide to constructing word processing files using the AppleWorks software on the Apple IIe computer covers (1) loading the program; (2) adding files to the desktop; (3) selecting the word processor option; (4) naming the file; (5) setting tabs; (6) selecting print options; and (7) saving the file. Sixteen sample screen displays…

  7. Constructing AppleWorks Data Base Files for the Apple IIe Computer.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This step-by-step guide to creating database files using the AppleWorks software on the Apple IIe computer covers (1) loading the program; (2) adding files to the desktop; (3) selecting the database option; (4) naming the file; (5) naming categories or fields; (6) inserting data; (7) changing database file formats; (8) altering the file layout;…

  8. Printing AppleWorks V2.0 Spreadsheet Files Using the Apple IIGS Computer.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This guide was developed as a "how to" training device for printing AppleWorks version 2.0 spreadsheet files using the Apple IIGS computer with two disk drives. Step-by-step instructions are provided for loading spreadsheet files; selecting the print option; printing entire files; and for printing specific rows, columns, or blocks of the…

  9. Printing AppleWorks V2.0 Word Processing Files Using the Apple IIGS Computer.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This guide was developed as a "how to" training device for printing AppleWorks version 2.0 word processor files using the Apple IIGS computer with two disk drives. Step-by-step instructions are provided for loading the word processor files, selecting the print option, printing files, and obtaining additional help. For each step, a…

  10. HPLC-DAD-MS Profiling of Polyphenols Responsible for the Yellow-Orange Color in Apple Juices of Different French Cider Apple Varieties.

    PubMed

    Le Deun, Erell; Van der Werf, Remmelt; Le Bail, Gildas; Le Quéré, Jean-Michel; Guyot, Sylvain

    2015-09-09

    The pigments responsible for the yellow-orange coloration of apple juices have remained largely unknown up to now. Four French cider apple juices were produced in conditions similar to those used in the cider-making industry. The oxidized juices, characterized using the CIE L a b parameters, displayed various colors depending on the apple variety and native phenolic composition. HPLC-DAD-MS revealed contrasting pigment profiles related to oxidized tanning and nontanning molecules. The latter were divided into two groups according to their polarity and their visible spectra. With regard to phenolic classes, flavanol monomers and hydroxycinnamic acids played an essential role in the formation of oxidation products. Interestingly, dihydrochalcones appeared to include precursors of some yellow compounds. Indeed, the yellow pigment phloretin xyloglucoside oxidation product (PXGOPj), derived from phloretin xyloglucoside, was clearly identified in apple juices as a xyloglucose analogue of the yellow pigment phloridzin oxidation product (POPj), previously characterized in a model solution by Le Guernevé et al. (Tetrahedron Lett. 2004, 45 (35), 6673-6677).

  11. The history of Newton's apple tree

    NASA Astrophysics Data System (ADS)

    Keesing, R. G.

    1998-05-01

    This article contains a brief introduction to Newton's early life to put into context the subsequent events in this narrative. It is followed by a summary of accounts of Newton's famous story of his discovery of universal gravitation which was occasioned by the fall of an apple in the year 1665/6. Evidence of Newton's friendship with a prosperous Yorkshire family who planted an apple tree arbour in the early years of the eighteenth century to celebrate his discovery is presented. A considerable amount of new and unpublished pictorial and documentary material is included relating to a particular apple tree which grew in the garden of Woolsthorpe Manor (Newton's birthplace) and which blew down in a storm before the year 1816. Evidence is then presented which describes how this tree was chosen to be the focus of Newton's account. Details of the propagation of the apple tree growing in the garden at Woolsthorpe in the early part of the last century are then discussed, and the results of a dendrochronological study of two of these trees is presented. It is then pointed out that there is considerable evidence to show that the apple tree presently growing at Woolsthorpe and known as 'Newton's apple tree' is in fact the same specimen which was identified in the middle of the eighteenth century and which may now be 350 years old. In conclusion early results from a radiocarbon dating study being carried out at the University of Oxford on core samples from the Woolsthorpe tree lend support to the contention that the present tree is one and the same as that identified as Newton's apple tree more than 200 years ago. Very recently genetic fingerprinting techniques have been used in an attempt to identify from which sources the various 'Newton apple trees' planted throughout the world originate. The tentative result of this work suggests that there are two separate varieties of apple tree in existence which have been accepted as 'the tree'. One may conclude that at least some of

  12. OPT3 is a component of the iron-signaling network between leaves and roots and misregulation of OPT3 leads to an over-accumulation of cadmium in seeds.

    PubMed

    Mendoza-Cózatl, David G; Xie, Qingqing; Akmakjian, Garo Z; Jobe, Timothy O; Patel, Ami; Stacey, Minviluz G; Song, Lihui; Demoin, Dustin Wayne; Jurisson, Silvia S; Stacey, Gary; Schroeder, Julian I

    2014-09-01

    Plants and seeds are the main dietary sources of zinc, iron, manganese, and copper, but are also the main entry point for toxic elements such as cadmium into the food chain. We report here that an Arabidopsis oligopeptide transporter mutant, opt3-2, over-accumulates cadmium (Cd) in seeds and roots but, unexpectedly, under-accumulates Cd in leaves. The cadmium distribution in opt3-2 differs from iron, zinc, and manganese, suggesting a metal-specific mechanism for metal partitioning within the plant. The opt3-2 mutant constitutively up-regulates the Fe/Zn/Cd transporter IRT1 and FRO2 in roots, indicative of an iron-deficiency response. No genetic mutants that impair the shoot-to-root signaling of iron status in leaves have been identified. Interestingly, shoot-specific expression of OPT3 rescues the Cd sensitivity and complements the aberrant expression of IRT1 in opt3-2 roots, suggesting that OPT3 is required to relay the iron status from leaves to roots. OPT3 expression was found in the vasculature with preferential expression in the phloem at the plasma membrane. Using radioisotope experiments, we found that mobilization of Fe from leaves is severely affected in opt3-2, suggesting that Fe mobilization out of leaves is required for proper trace-metal homeostasis. When expressed in yeast, OPT3 does not localize to the plasma membrane, precluding the identification of the OPT3 substrate. Our in planta results show that OPT3 is important for leaf phloem-loading of iron and plays a key role regulating Fe, Zn, and Cd distribution within the plant. Furthermore, ferric chelate reductase activity analyses provide evidence that iron is not the sole signal transferred from leaves to roots in leaf iron status signaling.

  13. OPT3 Is a Component of the Iron-Signaling Network between Leaves and Roots and Misregulation of OPT3 Leads to an Over-Accumulation of Cadmium in Seeds

    PubMed Central

    Mendoza-Cózatl, David G.; Xie, Qingqing; Akmakjian, Garo Z.; Jobe, Timothy O.; Patel, Ami; Stacey, Minviluz G.; Song, Lihui; Demoin, Dustin Wayne; Jurisson, Silvia S.; Stacey, Gary; Schroeder, Julian I.

    2014-01-01

    Plants and seeds are the main dietary sources of zinc, iron, manganese, and copper, but are also the main entry point for toxic elements such as cadmium into the food chain. We report here that an Arabidopsis oligopeptide transporter mutant, opt3-2, over-accumulates cadmium (Cd) in seeds and roots but, unexpectedly, under-accumulates Cd in leaves. The cadmium distribution in opt3-2 differs from iron, zinc, and manganese, suggesting a metal-specific mechanism for metal partitioning within the plant. The opt3-2 mutant constitutively up-regulates the Fe/Zn/Cd transporter IRT1 and FRO2 in roots, indicative of an iron-deficiency response. No genetic mutants that impair the shoot-to-root signaling of iron status in leaves have been identified. Interestingly, shoot-specific expression of OPT3 rescues the Cd sensitivity and complements the aberrant expression of IRT1 in opt3-2 roots, suggesting that OPT3 is required to relay the iron status from leaves to roots. OPT3 expression was found in the vasculature with preferential expression in the phloem at the plasma membrane. Using radioisotope experiments, we found that mobilization of Fe from leaves is severely affected in opt3-2, suggesting that Fe mobilization out of leaves is required for proper trace-metal homeostasis. When expressed in yeast, OPT3 does not localize to the plasma membrane, precluding the identification of the OPT3 substrate. Our in planta results show that OPT3 is important for leaf phloem-loading of iron and plays a key role regulating Fe, Zn, and Cd distribution within the plant. Furthermore, ferric chelate reductase activity analyses provide evidence that iron is not the sole signal transferred from leaves to roots in leaf iron status signaling. PMID:24880337

  14. A Comprehensive Review of Apples and Apple Components and Their Relationship to Human Health12

    PubMed Central

    Hyson, Dianne A.

    2011-01-01

    There has been an increasing appreciation and understanding of the link between dietary fruit and vegetable intake and improved health in humans. The widespread and growing intake of apples and apple juice/products and their rich phytochemical profile suggest their important potential to affect the health of the populations consuming them. This review summarizes current clinical, in vitro, and in vivo data and builds upon earlier published reports that apple may reduce the risk of chronic disease by various mechanisms, including antioxidant, antiproliferative, and cell signaling effects. Exposure to apples and apple products has been associated with beneficial effects on risk, markers, and etiology of cancer, cardiovascular disease, asthma, and Alzheimer’s disease. Recent work suggests that these products may also be associated with improved outcomes related to cognitive decline of normal aging, diabetes, weight management, bone health, pulmonary function, and gastrointestinal protection. PMID:22332082

  15. Cisgenic apple trees; development, characterization, and performance

    PubMed Central

    Krens, Frans A.; Schaart, Jan G.; van der Burgh, Aranka M.; Tinnenbroek-Capel, Iris E. M.; Groenwold, Remmelt; Kodde, Linda P.; Broggini, Giovanni A. L.; Gessler, Cesare; Schouten, Henk J.

    2015-01-01

    Two methods were developed for the generation of cisgenic apples. Both have been successfully applied producing trees. The first method avoids the use of any foreign selectable marker genes; only the gene-of-interest is integrated between the T-DNA border sequences. The second method makes use of recombinase-based marker excision. For the first method we used the MdMYB10 gene from a red-fleshed apple coding for a transcription factor involved in regulating anthocyanin biosynthesis. Red plantlets were obtained and presence of the cisgene was confirmed. Plantlets were grafted and grown in a greenhouse. After 3 years, the first flowers appeared, showing red petals. Pollination led to production of red-fleshed cisgenic apples. The second method used the pM(arker)F(ree) vector system, introducing the scab resistance gene Rvi6, derived from apple. Agrobacterium-mediated transformation, followed by selection on kanamycin, produced genetically modified apple lines. Next, leaves from in vitro material were treated to activate the recombinase leading to excision of selection genes. Subsequently, the leaf explants were subjected to negative selection for marker-free plantlets by inducing regeneration on medium containing 5-fluorocytosine. After verification of the marker-free nature, the obtained plants were grafted onto rootstocks. Young trees from four cisgenic lines and one intragenic line, all containing Rvi6, were planted in an orchard. Appropriate controls were incorporated in this trial. We scored scab incidence for three consecutive years on leaves after inoculations with Rvi6-avirulent strains. One cisgenic line and the intragenic line performed as well as the resistant control. In 2014 trees started to overcome their juvenile character and formed flowers and fruits. The first results of scoring scab symptoms on apple fruits were obtained. Apple fruits from susceptible controls showed scab symptoms, while fruits from cisgenic and intragenic lines were free of scab

  16. 40 CFR 407.20 - Applicability; description of the apple products subcategory.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 29 2011-07-01 2009-07-01 true Applicability; description of the apple... SOURCE CATEGORY Apple Products Subcategory § 407.20 Applicability; description of the apple products... apples into apple products. The processing of apples into caustic peeled or dehydrated products...

  17. 40 CFR 407.20 - Applicability; description of the apple products subcategory.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 29 2014-07-01 2012-07-01 true Applicability; description of the apple... SOURCE CATEGORY Apple Products Subcategory § 407.20 Applicability; description of the apple products... apples into apple products. The processing of apples into caustic peeled or dehydrated products...

  18. 40 CFR 407.10 - Applicability; description of the apple juice subcategory.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 29 2011-07-01 2009-07-01 true Applicability; description of the apple... SOURCE CATEGORY Apple Juice Subcategory § 407.10 Applicability; description of the apple juice... apples into apple juice or apple cider. When a plant is subject to effluent limitations covering...

  19. 40 CFR 407.20 - Applicability; description of the apple products subcategory.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Applicability; description of the apple... SOURCE CATEGORY Apple Products Subcategory § 407.20 Applicability; description of the apple products... apples into apple products. The processing of apples into caustic peeled or dehydrated products...

  20. 40 CFR 407.20 - Applicability; description of the apple products subcategory.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 30 2013-07-01 2012-07-01 true Applicability; description of the apple... SOURCE CATEGORY Apple Products Subcategory § 407.20 Applicability; description of the apple products... apples into apple products. The processing of apples into caustic peeled or dehydrated products...

  1. 40 CFR 407.10 - Applicability; description of the apple juice subcategory.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 29 2014-07-01 2012-07-01 true Applicability; description of the apple... SOURCE CATEGORY Apple Juice Subcategory § 407.10 Applicability; description of the apple juice... apples into apple juice or apple cider. When a plant is subject to effluent limitations covering...

  2. 40 CFR 407.10 - Applicability; description of the apple juice subcategory.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Applicability; description of the apple... SOURCE CATEGORY Apple Juice Subcategory § 407.10 Applicability; description of the apple juice... apples into apple juice or apple cider. When a plant is subject to effluent limitations covering...

  3. 40 CFR 407.20 - Applicability; description of the apple products subcategory.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... apple products subcategory. 407.20 Section 407.20 Protection of Environment ENVIRONMENTAL PROTECTION... PROCESSING POINT SOURCE CATEGORY Apple Products Subcategory § 407.20 Applicability; description of the apple... processing of apples into apple products. The processing of apples into caustic peeled or dehydrated...

  4. 40 CFR 407.10 - Applicability; description of the apple juice subcategory.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... apple juice subcategory. 407.10 Section 407.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... SOURCE CATEGORY Apple Juice Subcategory § 407.10 Applicability; description of the apple juice... apples into apple juice or apple cider. When a plant is subject to effluent limitations covering...

  5. 40 CFR 407.10 - Applicability; description of the apple juice subcategory.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 30 2013-07-01 2012-07-01 true Applicability; description of the apple... SOURCE CATEGORY Apple Juice Subcategory § 407.10 Applicability; description of the apple juice... apples into apple juice or apple cider. When a plant is subject to effluent limitations covering...

  6. Biotechnology and apple breeding in Japan

    PubMed Central

    Igarashi, Megumi; Hatsuyama, Yoshimichi; Harada, Takeo; Fukasawa-Akada, Tomoko

    2016-01-01

    Apple is a fruit crop of significant economic importance, and breeders world wide continue to develop novel cultivars with improved characteristics. The lengthy juvenile period and the large field space required to grow apple populations have imposed major limitations on breeding. Various molecular biological techniques have been employed to make apple breeding easier. Transgenic technology has facilitated the development of apples with resistance to fungal or bacterial diseases, improved fruit quality, or root stocks with better rooting or dwarfing ability. DNA markers for disease resistance (scab, powdery mildew, fire-blight, Alternaria blotch) and fruit skin color have also been developed, and marker-assisted selection (MAS) has been employed in breeding programs. In the last decade, genomic sequences and chromosome maps of various cultivars have become available, allowing the development of large SNP arrays, enabling efficient QTL mapping and genomic selection (GS). In recent years, new technologies for genetic improvement, such as trans-grafting, virus vectors, and genome-editing, have emerged. Using these techniques, no foreign genes are present in the final product, and some of them show considerable promise for application to apple breeding. PMID:27069388

  7. Goldstone-Apple Valley Radio Telescope System Theory of Operation

    NASA Technical Reports Server (NTRS)

    Stephan, George R.

    1997-01-01

    The purpose of this learning module is to enable learners to describe how the Goldstone-Apple Valley Radio Telescope (GAVRT) system functions in support of Apple Valley Science and Technology Center's (AVSTC) client schools' radio astronomy activities.

  8. Prediction and diagnosis of apple fruit physiological disorders

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apple postharvest physiological disorders, characterized by peel or flesh necrosis, result in significant yearly financial losses in commercial operations. Stakeholders have identified the need for effective, consistent control measures for apple postharvest physiological disorders and the developme...

  9. Using the Apple II as a Laboratory Instrument.

    ERIC Educational Resources Information Center

    De Jong, Marvin L.; Layman, John W.

    1984-01-01

    Discusses using Apple II microcomputers for measuring resistance, temperature, and light intensity. Also discusses digital input and output and timing techniques. Although focusing on Apple II, the circuits and programs described may be applicable to other microcomputers. (JN)

  10. Production of fuels and chemicals from apple pomace

    SciTech Connect

    Hang, Y.D.

    1987-03-01

    Nearly 36 million tons of apples are produced annually in the US. Approximately 45% of the total US apple production is used for processing purposes. The primary by-product of apple processing is apple pomace. It consists of the presscake resulting from pressing apples for juice or cider, including the presscake obtained in pressing peel and core wastes generated in the manufacture of apple sauce or slices. More than 500 food processing plants in the US produce a total of about 1.3 million metric tons of apple pomace each year, and it is likely that annual disposal fees exceed $10 million. Apple pomace has the potential to be used for the production of fuels (ethanol and biogas containing 60% methane) and food-grade chemicals. These uses will be reviewed in this article.

  11. Enhanced recovery of Salmonella from apple cider and apple juice with universal preenrichment broth.

    PubMed

    Hammack, Thomas S; Johnson, Mildred L; Jacobson, Andrew P; Andrews, Wallace H

    2002-01-01

    A comparison was made of the relative efficiencies of Universal Preenrichment (UP) broth and lactose broth for the recovery of a variety of Salmonella serovars from pasteurized and unpasteurized apple cider and pasteurized apple juice. Bulk portions of juice were contaminated with single Salmonella serovars at high and low levels of 0.4 and 0.04 CFU/mL, respectively. The juice was aged for a minimum of 5 days at 2-5 degrees C. On the day analysis was initiated, each of 20 test portions (25 mL) of the contaminated juice was preenriched in UP broth and in lactose broth. The Bacteriological Analytical Manual Salmonella culture method was followed thereafter. For pasteurized apple cider, UP broth recovered significantly (p < 0.05) more Salmonella-positive test portions than did lactose broth (112 and 75, respectively). For unpasteurized apple cider, UP broth recovered significantly more Salmonella-positive test portions than did lactose broth (326 and 221, respectively). For pasteurized apple juice, UP broth recovered more Salmonella-positive test portions than did lactose broth (93 and 81, respectively). However, this difference was not statistically significant. These results indicate that UP broth should replace lactose broth for the analysis of pasteurized and unpasteurized apple cider and pasteurized apple juice.

  12. 40 CFR 96.388 - CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units. 96.388 Section 96.388 Protection of Environment... SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR NOX Ozone Season Opt-in Units § 96.388...

  13. 40 CFR 96.388 - CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units. 96.388 Section 96.388 Protection of Environment... SO 2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR NOX Ozone Season Opt-in Units § 96.388...

  14. 40 CFR 97.388 - CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units. 97.388 Section 97.388 Protection of Environment... NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Opt-in Units § 97.388 CAIR NOX Ozone...

  15. 40 CFR 96.388 - CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units. 96.388 Section 96.388 Protection of Environment... SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR NOX Ozone Season Opt-in Units § 96.388...

  16. 40 CFR 96.388 - CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units. 96.388 Section 96.388 Protection of Environment... SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR NOX Ozone Season Opt-in Units § 96.388...

  17. 40 CFR 97.388 - CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units. 97.388 Section 97.388 Protection of Environment... NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Opt-in Units § 97.388 CAIR NOX Ozone...

  18. 40 CFR 97.388 - CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units. 97.388 Section 97.388 Protection of Environment... NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Opt-in Units § 97.388 CAIR NOX Ozone...

  19. 40 CFR 97.388 - CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units. 97.388 Section 97.388 Protection of Environment... NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Opt-in Units § 97.388 CAIR NOX Ozone...

  20. 40 CFR 97.388 - CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units. 97.388 Section 97.388 Protection of Environment... NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Opt-in Units § 97.388 CAIR NOX Ozone...

  1. 40 CFR 96.388 - CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false CAIR NOX Ozone Season allowance allocations to CAIR NOX Ozone Season opt-in units. 96.388 Section 96.388 Protection of Environment... SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR NOX Ozone Season Opt-in Units § 96.388...

  2. 75 FR 38799 - Reedsport OPT Wave Park, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... OPT Wave Park, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications June 24, 2010. Reedsport OPT Wave Park, LLC... Wave Park Phase III Project located in the Pacific Ocean about 2.5 miles west of Reedsport, Oregon....

  3. Forum: Making Sense of the Opt-Out Movement: "Education Next" Talks with Scott Levy and Jonah Edelman

    ERIC Educational Resources Information Center

    Levy, Scott; Edelman, Jonah

    2016-01-01

    Over the past few years, students by the thousands have refused to take their state's standardized tests. This "opt-out" phenomenon has prompted debate in state legislatures and in Washington, putting states at risk of losing Title I funds. Advocates describe opt-out as a grassroots movement of parents concerned about overtesting,…

  4. 17 CFR 162.5 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Affiliate Marketing Rules § 162.5 Contents of opt-out notice; consolidated and equivalent notices. (a... marketing than is required by this subpart, the requirements of this section may be satisfied by providing... notices in the FCRA or the GLB Act privacy notices. (e) Equivalent notices. A notice or disclosure that...

  5. 40 CFR 97.285 - CAIR opt-in permit contents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) The unit's baseline heat input under § 97.284(c); (4) The unit's baseline SO2 emission rate under § 97... requirements of § 97.287. (b) Each CAIR opt-in permit is deemed to incorporate automatically the definitions...

  6. 40 CFR 97.185 - CAIR opt-in permit contents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) The unit's baseline heat input under § 97.184(c); (4) The unit's baseline NOX emission rate under § 97... requirements of § 97.187. (b) Each CAIR opt-in permit is deemed to incorporate automatically the definitions...

  7. 40 CFR 97.285 - CAIR opt-in permit contents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) The unit's baseline heat input under § 97.284(c); (4) The unit's baseline SO2 emission rate under § 97... requirements of § 97.287. (b) Each CAIR opt-in permit is deemed to incorporate automatically the definitions...

  8. 40 CFR 97.185 - CAIR opt-in permit contents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) The unit's baseline heat input under § 97.184(c); (4) The unit's baseline NOX emission rate under § 97... requirements of § 97.187. (b) Each CAIR opt-in permit is deemed to incorporate automatically the definitions...

  9. 16 CFR 680.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... equivalent notices. 680.23 Section 680.23 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT... listing the name of each affiliate providing the notice. But if the affiliates providing the joint notice... renewal notice; and (vii) A reasonable and simple method for the consumer to opt out. (2)...

  10. 17 CFR 160.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... requirements for service providers and joint marketing. 160.13 Section 160.13 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 160.13 Exception to opt out requirements for service providers and joint marketing. (a) General rule. (1) The...

  11. 16 CFR 680.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... equivalent notices. 680.23 Section 680.23 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT... listing the name of each affiliate providing the notice. But if the affiliates providing the joint notice... renewal notice; and (vii) A reasonable and simple method for the consumer to opt out. (2)...

  12. 17 CFR 248.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requirements for service providers and joint marketing. 248.13 Section 248.13 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of... out requirements for service providers and joint marketing. (a) General rule. (1) The opt...

  13. 40 CFR 96.185 - CAIR opt-in permit contents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false CAIR opt-in permit contents. 96.185 Section 96.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION...

  14. 40 CFR 96.183 - Applying for CAIR opt-in permit.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Applying for CAIR opt-in permit. 96.183 Section 96.183 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION...

  15. 40 CFR 96.185 - CAIR opt-in permit contents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false CAIR opt-in permit contents. 96.185 Section 96.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION...

  16. 40 CFR 96.183 - Applying for CAIR opt-in permit.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Applying for CAIR opt-in permit. 96.183 Section 96.183 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION...

  17. 12 CFR 573.15 - Other exceptions to notice and opt out requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Other exceptions to notice and opt out requirements. 573.15 Section 573.15 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY... requirements; (ii) To comply with a properly authorized civil, criminal, or regulatory investigation,...

  18. 12 CFR 573.15 - Other exceptions to notice and opt out requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 6 2013-01-01 2012-01-01 true Other exceptions to notice and opt out requirements. 573.15 Section 573.15 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY... requirements; (ii) To comply with a properly authorized civil, criminal, or regulatory investigation,...

  19. 16 CFR 680.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Delivery of opt-out notices. 680.26 Section 680.26 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT AFFILIATE MARKETING... or the provisions in section 101 of the Electronic Signatures in Global and National Commerce Act,...

  20. 48 CFR 452.236-79 - Opted Timber Sale Road Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Opted Timber Sale Road Requirements. 452.236-79 Section 452.236-79 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses...

  1. Optimization guide for programs compiled under IBM FORTRAN H (OPT=2)

    NASA Technical Reports Server (NTRS)

    Smith, D. M.; Dobyns, A. H.; Marsh, H. M.

    1977-01-01

    Guidelines are given to provide the programmer with various techniques for optimizing programs when the FORTRAN IV H compiler is used with OPT=2. Subroutines and programs are described in the appendices along with a timing summary of all the examples given in the manual.

  2. Opt Out: An Examination of Issues. Research Report. ETS RR-16-13

    ERIC Educational Resources Information Center

    Bennett, Randy E.

    2016-01-01

    Media reports have recently given significant attention to the opt-out movement, an organized effort to refuse to take standardized tests. Although the narrative often told in early press accounts was of a viral grass-roots effort led by parents who object to state-mandated testing, the reality has turned out to be more complicated. Through a…

  3. 17 CFR 160.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Delivering privacy and opt out notices. 160.9 Section 160.9 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION... web site to access financial products and services electronically and agrees to receive notices at...

  4. 17 CFR 160.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Delivering privacy and opt out notices. 160.9 Section 160.9 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION...: (1) The customer uses your web site to access financial products and services electronically...

  5. 17 CFR 162.7 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Reasonable and simple methods of opting out. 162.7 Section 162.7 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... electronically mailed or processed through an Internet Web site; (4) Providing a toll-free telephone number;...

  6. 17 CFR 248.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Delivering privacy and opt out notices. 248.9 Section 248.9 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... customer uses your web site to access financial products and services electronically and agrees to...

  7. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Reasonable and simple methods of opting out. 248.125 Section 248.125 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... electronically mailed or processed at an Internet Web site, if the consumer agrees to the electronic delivery...

  8. Opt-Outs: What Is Lost When Students Do Not Test. Issue Brief

    ERIC Educational Resources Information Center

    Croft, Michelle

    2015-01-01

    Scores on annual statewide achievement tests can provide parents, students, educators, and policymakers with valuable information--but only if students participate. This issue brief provides the background about recent increases in (and efforts to expand) the number of students opting out of statewide assessments, describes the information and…

  9. 12 CFR Appendix C to Part 222 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... SYSTEM FAIR CREDIT REPORTING (REGULATION V) Pt. 222, App. C Appendix C to Part 222—Model Forms for Opt... limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.---.com • By mail... the Web: www.---.com • By mail: Check the box and complete the form below, and send the form to:...

  10. 12 CFR Appendix C to Part 717 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FAIR CREDIT REPORTING Pt. 717, App. C Appendix C to Part 717—Model Forms for Opt-Out Notices a..., contact us : • By telephone: 1-877-###-#### • On the Web: www.---.com • By mail: Check the box and... renewal notice. To limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web:...

  11. 12 CFR Appendix C to Part 222 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SYSTEM FAIR CREDIT REPORTING (REGULATION V) Pt. 222, App. C Appendix C to Part 222—Model Forms for Opt...: 1-877-###-#### • On the Web: www.---.com • By mail: Check the box and complete the form below, and... limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.---.com • By...

  12. 12 CFR Appendix C to Part 717 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... FAIR CREDIT REPORTING Pt. 717, App. C Appendix C to Part 717—Model Forms for Opt-Out Notices a..., contact us : • By telephone: 1-877-###-#### • On the Web: www.---.com • By mail: Check the box and... renewal notice. To limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web:...

  13. Opt-out HIV testing: an ethical analysis of women's reproductive rights.

    PubMed

    Fields, Loren; Kaplan, Clair

    2011-09-01

    As the HIV epidemic continues to grow worldwide, women are increasingly and disproportionally affected. With the introduction of anti-retroviral medications that have been found to effectively prevent perinatal transmission of HIV, the approach to HIV testing in pregnant women has grown increasingly more controversial. In recent years, the model of voluntary counseling and testing (VCT) has come into question with opt-out testing now advocated for by the Centers for Disease Control and occurring widely in pregnancy. The benefits of opt-out testing are numerous and may justify its use in replacing the VCT that many have come to see as insufficient. An ethical analysis of opt-out testing suggests it may be at odds with true informed consent and involve a degree of coercion that would not be allowed outside the prenatal setting. If opt-out testing is going to remain the standard of care then the ethical issues it raises must be made transparent. Strategies need to be designed for ensuring that HIV counseling and testing in pregnancy is done in accordance with ethical and reproductive rights principles.

  14. 42 CFR 405.420 - Requirements of the opt-out affidavit.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 405.420 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN..., during the opt-out period, the physician or practitioner understands that he or she may receive no direct... understands that a beneficiary who has not entered into a private contract and who requires emergency...

  15. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Reasonable and simple methods of opting out. 248.125 Section 248.125 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §...

  16. 17 CFR 248.122 - Scope and duration of opt out.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Scope and duration of opt out. 248.122 Section 248.122 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing §...

  17. 17 CFR 248.122 - Scope and duration of opt out.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Scope and duration of opt out. 248.122 Section 248.122 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.122 Scope...

  18. 17 CFR 162.4 - Scope and duration of opt out.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Scope and duration of opt out. 162.4 Section 162.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION PROTECTION OF CONSUMER INFORMATION UNDER THE FAIR CREDIT REPORTING ACT Business Affiliate Marketing Rules §...

  19. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Reasonable and simple methods of opting out. 248.125 Section 248.125 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate...

  20. 17 CFR 248.122 - Scope and duration of opt out.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Scope and duration of opt out. 248.122 Section 248.122 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.122 Scope...

  1. 12 CFR 41.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.23 Contents of opt-out notice; consolidated and... provided by “all of the ABC companies,” “the ABC banking, credit card, insurance, and securities companies... securities companies,” or by listing the name of each affiliate providing the notice. But if the...

  2. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Reasonable and simple methods of opting out. 248.125 Section 248.125 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §...

  3. 12 CFR 41.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.23 Contents of opt-out notice; consolidated and... provided by “all of the ABC companies,” “the ABC banking, credit card, insurance, and securities companies... securities companies,” or by listing the name of each affiliate providing the notice. But if the...

  4. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Reasonable and simple methods of opting out. 248.125 Section 248.125 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §...

  5. 17 CFR 248.122 - Scope and duration of opt out.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Scope and duration of opt out. 248.122 Section 248.122 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.122 Scope...

  6. 17 CFR 162.4 - Scope and duration of opt out.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Scope and duration of opt out. 162.4 Section 162.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION PROTECTION OF CONSUMER INFORMATION UNDER THE FAIR CREDIT REPORTING ACT Business Affiliate Marketing Rules §...

  7. 17 CFR 162.4 - Scope and duration of opt out.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Scope and duration of opt out. 162.4 Section 162.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION (CONTINUED) PROTECTION OF CONSUMER INFORMATION UNDER THE FAIR CREDIT REPORTING ACT Business Affiliate Marketing...

  8. Opt Out: Women with Children Leaving Mid-Level Student Affairs Positions

    ERIC Educational Resources Information Center

    Hebreard, Dana

    2010-01-01

    This phenomenological study is about the decision-making process of women with young children at the mid-level student affairs position who decide to opt out of their career for a minimum of one year, and for some, return to higher education. The study is based on interviews with 17 mid-level college administrators and mothers of young children,…

  9. 5 CFR 894.404 - May I opt out of premium conversion?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false May I opt out of premium conversion? 894.404 Section 894.404 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE PROGRAM Cost of Coverage § 894.404 May...

  10. 5 CFR 894.404 - May I opt out of premium conversion?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false May I opt out of premium conversion? 894.404 Section 894.404 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE PROGRAM Cost of Coverage § 894.404 May...

  11. 5 CFR 894.404 - May I opt out of premium conversion?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false May I opt out of premium conversion? 894.404 Section 894.404 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE PROGRAM Cost of Coverage § 894.404 May...

  12. 5 CFR 894.404 - May I opt out of premium conversion?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false May I opt out of premium conversion? 894.404 Section 894.404 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE PROGRAM Cost of Coverage § 894.404 May...

  13. 5 CFR 894.404 - May I opt out of premium conversion?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false May I opt out of premium conversion? 894.404 Section 894.404 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE PROGRAM Cost of Coverage § 894.404 May...

  14. 17 CFR 248.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Consumer Financial Information and Safeguarding Personal Information Exceptions § 248.13 Exception to opt... nonpublic personal information under this section to a financial institution with which you perform joint... requirements in §§ 248.7 and 248.10 do not apply when you provide nonpublic personal information to...

  15. 17 CFR 248.15 - Other exceptions to notice and opt out requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Exceptions § 248.15 Other exceptions to notice and opt out requirements. (a... providers and joint marketing do not apply when you disclose nonpublic personal information: (1) With...

  16. 12 CFR 216.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... disclose nonpublic personal information under this section to a financial institution with which you... GOVERNORS OF THE FEDERAL RESERVE SYSTEM PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) Exceptions.... (1) The opt out requirements in §§ 216.7 and 216.10 do not apply when you provide nonpublic...

  17. 12 CFR 40.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... discloses nonpublic personal information under this section to a financial institution with which the bank... OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 40.13 Exception to opt out....7 and 40.10 do not apply when a bank provides nonpublic personal information to a...

  18. 12 CFR 573.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... business to carry out those purposes. (2) Example. If you disclose nonpublic personal information under..., DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 573.13 Exception to opt out... §§ 573.7 and 573.10 do not apply when you provide nonpublic personal information to a nonaffiliated...

  19. 12 CFR 40.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... discloses nonpublic personal information under this section to a financial institution with which the bank... OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 40.13 Exception to opt out....7 and 40.10 do not apply when a bank provides nonpublic personal information to a...

  20. 12 CFR 573.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... business to carry out those purposes. (2) Example. If you disclose nonpublic personal information under..., DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 573.13 Exception to opt out... §§ 573.7 and 573.10 do not apply when you provide nonpublic personal information to a nonaffiliated...

  1. 12 CFR 216.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... disclose nonpublic personal information under this section to a financial institution with which you... GOVERNORS OF THE FEDERAL RESERVE SYSTEM PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) Exceptions.... (1) The opt out requirements in §§ 216.7 and 216.10 do not apply when you provide nonpublic...

  2. 12 CFR 573.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... business to carry out those purposes. (2) Example. If you disclose nonpublic personal information under..., DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 573.13 Exception to opt out... §§ 573.7 and 573.10 do not apply when you provide nonpublic personal information to a nonaffiliated...

  3. 12 CFR 40.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... discloses nonpublic personal information under this section to a financial institution with which the bank... OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 40.13 Exception to opt out....7 and 40.10 do not apply when a bank provides nonpublic personal information to a...

  4. 12 CFR 40.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... discloses nonpublic personal information under this section to a financial institution with which the bank... OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 40.13 Exception to opt out....7 and 40.10 do not apply when a bank provides nonpublic personal information to a...

  5. 7 CFR 33.12 - Apples not subject to regulation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 2 2012-01-01 2012-01-01 false Apples not subject to regulation. 33.12 Section 33.12... REGULATIONS REGULATIONS ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Exemptions § 33.12 Apples not subject... this part, transport or receive for transportation to any foreign destination: (a) A quantity of...

  6. 7 CFR 33.12 - Apples not subject to regulation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false Apples not subject to regulation. 33.12 Section 33.12... REGULATIONS REGULATIONS ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Exemptions § 33.12 Apples not subject... this part, transport or receive for transportation to any foreign destination: (a) A quantity of...

  7. 7 CFR 33.12 - Apples not subject to regulation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Apples not subject to regulation. 33.12 Section 33.12... REGULATIONS REGULATIONS ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Exemptions § 33.12 Apples not subject... this part, transport or receive for transportation to any foreign destination: (a) A quantity of...

  8. 7 CFR 33.12 - Apples not subject to regulation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Apples not subject to regulation. 33.12 Section 33.12... REGULATIONS REGULATIONS ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Exemptions § 33.12 Apples not subject... this part, transport or receive for transportation to any foreign destination: (a) A quantity of...

  9. 7 CFR 33.12 - Apples not subject to regulation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Apples not subject to regulation. 33.12 Section 33.12... REGULATIONS REGULATIONS ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Exemptions § 33.12 Apples not subject... this part, transport or receive for transportation to any foreign destination: (a) A quantity of...

  10. Transcriptomic analysis of apple fruit ripening and texture attributes

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Molecular events regulating cultivar-specific apple fruit ripening and sensory quality are largely unknown. Such knowledge is essential for genomic-assisted apple breeding and postharvest quality management. The ripening behavior and texture attributes of two apple cultivars, ‘Pink Lady’ and ‘Honey...

  11. Identification of external inoculum sources of apple replant pathogens

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apple replant disease (ARD) is an important disease world-wide and occurs when old apple orchards are replanted with apple. The disease is mainly caused by biological agents, since fumigation alleviates symptom development. The main ARD causative agents are fungi (Rhizoctonia solani AG-5 and AG-6, a...

  12. Cold Acclimation Improves Regrowth of Cryopreserved Apple Shoot Tips

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Cryopreservation is important for preserving the genetic resources of apple germplasm in Kazakhstan, the center of origin for apples. In this study of five apple genotypes [Malus domestica Borkh. and Malus sieversii (Ledeb.) M. Roem] we determined cold hardiness and the effect of cold acclimation o...

  13. Alar and Apples: Newspaper Coverage of a Major Risk Issue.

    ERIC Educational Resources Information Center

    Friedman, Sharon M.; And Others

    A study reviewed coverage in 13 newspapers during 1989 of the issue of spraying the pesticide Alar on apples. Using VU/TEXT, a newspaper database, 297 articles in 13 newspapers that included the specified code words "Alar" with or without "apple" or "apples" were retrieved and analyzed using a 33-question coding…

  14. Comment on 'Energy transfer in nanowire solar cells with photon-harvesting shells' [J. Appl. Phys. 105, 124509 (2009)

    SciTech Connect

    Markvart, T.; Danos, L.; Greef, R.

    2010-07-15

    In a recent article, Peters et al. [J. Appl. Phys. 105, 124509 (2009)] claim to have observed photosensitization of crystalline silicon by energy transfer from an optically absorbing thin polymer film. We show that this claim is not justified. Their experimental design is not adequate to establish enhanced photoexcitation of silicon; moreover, the theoretical arguments in their interpretation do not stand up to scrutiny.

  15. Exercising AppleWorks V2.0 Data Base Print Options with the Apple IIgs Computer. First Edition.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This is a step-by-step guide to using the AppleWorks software on the Apple IIGS computer to print AppleWorks database files in two types of formats--labels and tables. Steps covered for printing labels include naming the report, arranging or sorting, deleting a category, inserting a category, printing the category name and entry, selecting…

  16. Developing Simple Financial Records Using the AppleWorks Spreadsheet Subprogram, Apple IIe or GS Computers, and a Duodisk Drive.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This manual is a "how to" training device for developing simple financial records using the AppleWorks spreadsheet subprogram with an Apple IIe or Apple IIGS Computer which has a Duodisk or two disk drives. The manual provides step-by-step directions, and includes 34 figures depicting the computer screen at the various stages of the…

  17. Setting Up Letters Using the AppleWorks Word Processor Subprogram and Apple IIe or GS Computers.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This manual is a "how to" training device for setting up letter word processing files using the AppleWorks program with an Apple IIe or Apple IIGS computer which has a Duodisk or two disk drives and an 80-column card. The manual provides step-by-step directions, and includes 16 figures depicting the computer screen at the various stages…

  18. Developing Inventory Records Using the AppleWorks Data Base Subprogram and Apple IIe or GS Computers.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This manual is a "how to" training device for developing inventory records in the AppleWorks program using an Apple IIe or Apple IIGS Computer with Duodisk or two disk drives and an 80-column card. The manual provides step-by-step directions, and includes 17 figures depicting the computer screen at the various stages of the inventory…

  19. Developing Simple Budgets Using the AppleWorks Spreadsheet Subprogram, Apple IIe or GS Computers, and a Single Disk Drive.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This manual is a "how to" training device for developing spreadsheet files in the AppleWorks program using an Apple IIe or Apple IIGS Computer with a single disk drive. The manual provides step-by-step directions, and includes 36 figures depicting the computer screen at the various stages of the spreadsheet development sequence. (EW)

  20. Building Parts Inventory Files Using the AppleWorks Data Base Subprogram and Apple IIe or GS Computers.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This manual is a "how to" training device for building database files using the AppleWorks program with an Apple IIe or Apple IIGS Computer with Duodisk or two disk drives and an 80-column card. The manual provides step-by-step directions, and includes 25 figures depicting the computer screen at the various stages of the database file…

  1. Free galactose concentrations in fresh and stored apples (Malus domestica) and processed apple products.

    PubMed

    Scaman, Christine H; Jim, Vickie Jin Wai; Hartnett, Carol

    2004-02-11

    Gas chromatography was used to quantitate free galactose in Braeburn, Fuji, Red Delicious, and Spartan apples during cold storage, after thermal processing of apple slices and in juice produced using clarification and/or liquifaction enzymes. Spartan had significantly higher galactose levels as compared to Red Delicious apples, but changes in galactose in all varieties during 9 months of cold storage were insignificant. Blanching and canning decreased galactose levels, but doubling the thermal processing during canning increased the free galactose concentration detected in plant tissue. An enzymatic liquefaction aid used to prepare apple juice dramatically increased the free galactose content while a clarification aid caused only a slight increase due to its selective action on soluble pectin. These findings provide useful information for dietitians to base diet recommendations for galactosemic patients.

  2. Bioanalytical characterization of apple juice from 88 grafted and nongrafted apple varieties grown in Upper Austria.

    PubMed

    Lanzerstorfer, Peter; Wruss, Jürgen; Huemer, Stefan; Steininger, Andrea; Müller, Ulrike; Himmelsbach, Markus; Borgmann, Daniela; Winkler, Stephan; Höglinger, Otmar; Weghuber, Julian

    2014-02-05

    The compositional characteristics of untreated pure juice prepared from 88 apple varieties grown in the region of Eferding/Upper Austria were determined. Many of the analyzed varieties are noncommercial, old varieties not present in the market. The aim of the study was to quantitate the mineral, phosphate, trace elements, and polyphenolic content in order to identify varieties that are of particular interest for a wider distribution. Great variations among the investigated varieties could be found. This holds especially true for the total polyphenolic content (TPC) ranging from 103.2 to 2,275.6 mg/L. A clear dependence of the antioxidant capacity on the TPC levels was detected. Bioinformatics was employed to find specific interrelationships, such as Mg²⁺/Mn²⁺ and PO₄³⁻/K⁺, between the analyzed bio- and phytochemical parameters. Furthermore, special attention was drawn on putative effects of grafting on the phytochemical composition of apple varieties. By grafting 27 different apple varieties on two trees grown close to each other, it could be shown that the apple fruits remain their characteristic phytochemical composition. Finally, apple juice prepared from selected varieties was further characterized by additional biochemical analysis including cytotoxicity, epidermal growth factor receptor (EGFR) inhibition, and α-amylase activity tests. Cytotoxicity and inhibition of EGFR activation were found to be dependent on the TPC, while α-amylase activity was reduced by the apple juices independent of the presence of polyphenolic substances. Taken together selected apple varieties investigated within this study might serve as preferable sources for the development of apple-based food with a strong focus on health beneficial effects.

  3. Pre- and postharvest fungal apple diseases

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The domesticated apple (Malus domestica) is the most significant pome fruit grown and consumed worldwide. China is the largest producer followed by the United States on a global scale. However, fungal plant pathogens cause significant economic losses in the field and in storage which negatively impa...

  4. Hormonal and anatomical effects of apple rootstocks

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In greenhouse experiments, two-year-old 'Fuji' apple scions (Malus ×domestica, 'Fuji') on size-controlling rootstocks (dwarfing to vigorous), were grown for one season and shoot growth was measured to confirm size-controlling effects. In the next season, xylem sap was collected to determine hydraul...

  5. Small bowel obstruction caused by dried apple

    PubMed Central

    Ooi, Sally; Hong, Khiem

    2015-01-01

    Introduction Small bowel obstruction in a virgin abdomen is an uncommon surgical condition. While malignancy, inflammatory bowel disease and foreign body are the main reported causes, undigested food bezoar causing bowel obstruction is a rare entity. We report a case of small bowel obstruction secondary to dried preserved apple having re-expanded within the gastrointestinal tract. Presentation of case A 69 year old male presented with severe abdominal distension, generalized abdominal tenderness and obstipation for 1 week. Small bowel obstruction (SBO) was confirmed on plain abdominal X-ray and CT imaging. An emergency explorative laparatomy identified a sausage-shaped intra-luminal foreign body obstructing the distal ileum. An enterotomy was performed which revealed a rehydrated, donut-shaped piece of dried apple. Discussion Swallowed items that pass through the pylorus rarely cause obstruction as they are usually small enough to pass through the rest of the bowel without difficulty. We postulate that in our patient that the dried apple was originally small enough to pass through the pylorus. However during small bowel, its’ highly absorbable nature resulted in an increase in size that prevented its’ passage through the ileocecal valve. A simple in-vitro experiment discovered that dried apple has a potential to reabsorb fluid and expand up to 35% of its initial size within 72 h. Conclusion This report illustrates the potential for dried food substances to cause intra-luminal SBO after significant expansion with rehydration. PMID:25841159

  6. NEWTON'S APPLE 14th Season Teacher's Guide.

    ERIC Educational Resources Information Center

    Wichmann, Sue, Ed.

    This guide was developed to help teachers use the 14th season of NEWTON'S APPLE in their classrooms and contains lessons formatted to follow the National Science Education Standards. The "Overview,""Main Activity," and "Try-This" sections were created with inquiry-based learning in mind. Each lesson page begins with…

  7. APPLE In-Service Programming for Teachers.

    ERIC Educational Resources Information Center

    Burns, Edward

    This book is designed to provide teachers with techniques for entering and modifying BASIC programs on Apple computers. The underlying theme is that a teacher need not become a programmer to benefit from being able to use and modify BASIC programs. The key to the successful use of software in the classroom is the ability to individualize software…

  8. Lessons learned from the Apple stores.

    PubMed

    Pinkney, Henry; Baum, Neil

    2012-01-01

    Medical practices have an opportunity to improve the services that they offer their patients. Practices can look at other businesses and industries for examples of outstanding customer service. This article will discuss the services provided by Apple, Inc., and how medical practices can learn from this industry giant and improve the services that they offer patients.

  9. Making Apple Computers Accessible to Blind Children.

    ERIC Educational Resources Information Center

    Renouf, Andrew; Phillips, Susan

    The study examined the feasibility of adapting commercially available educational software to a speech synthesizer compatible with the Apple II for use with 15 visually impaired students 8 to 12 years old. Ss were pre-tested on measures of auditory discrimination, computer literacy, keyboard proficiency, spelling, and language. Ss then received…

  10. Some Aspects of Enzymatic Browning in Apples

    ERIC Educational Resources Information Center

    Liffen, C. L.; Cleeve, H. N.

    1975-01-01

    Describes material modified from the Nuffield advanced chemistry course to make it meaningful and relevant to pupils in the middle school. Discusses a series of simple experiments on apple browning and summarizes the browning process and its control. (Author/GS)

  11. Metabolomic Change Precedes Apple Superficial Scald Symptoms

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Metabolic profiling of 621 metabolites was employed to characterize metabolomic changes associated with ‘Granny Smith’ apple superficial scald development following 1-MCP or DPA treatment. Partial least squares-discriminant analyses were used to link metabolites with scald, postharvest treatments, ...

  12. Transcriptional analysis of apple fruit proanthocyanidin biosynthesis

    PubMed Central

    Henry-Kirk, Rebecca A.

    2012-01-01

    Proanthocyanidins (PAs) are products of the flavonoid pathway, which also leads to the production of anthocyanins and flavonols. Many flavonoids have antioxidant properties and may have beneficial effects for human health. PAs are found in the seeds and fruits of many plants. In apple fruit (Malus × domestica Borkh.), the flavonoid biosynthetic pathway is most active in the skin, with the flavan-3-ols, catechin, and epicatechin acting as the initiating units for the synthesis of PA polymers. This study examined the genes involved in the production of PAs in three apple cultivars: two heritage apple cultivars, Hetlina and Devonshire Quarrenden, and a commercial cultivar, Royal Gala. HPLC analysis shows that tree-ripe fruit from Hetlina and Devonshire Quarrenden had a higher phenolic content than Royal Gala. Epicatechin and catechin biosynthesis is under the control of the biosynthetic enzymes anthocyanidin reductase (ANR) and leucoanthocyanidin reductase (LAR1), respectively. Counter-intuitively, real-time quantitative PCR analysis showed that the expression levels of Royal Gala LAR1 and ANR were significantly higher than those of both Devonshire Quarrenden and Hetlina. This suggests that a compensatory feedback mechanism may be active, whereby low concentrations of PAs may induce higher expression of gene transcripts. Further investigation is required into the regulation of these key enzymes in apple. Abbreviations:ANOVAanalysis of varianceANRanthocyanidin reductaseDADdiode array detectorDAFBdays after full bloomDFRdihydroflavonol reductaseLARleucoanthocyanidin reductaseLC-MSliquid chromatography/mass spectrometryPAproanthocyanidinqPCRreal-time quantitative PCR PMID:22859681

  13. The Geneva apple rootstock breeding program

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The ancient practice of clonal propagation of perennial fruit crops by means of grafting was transformed when humans realized that certain properties of selected root systems could be beneficial for increasing productivity of that fruit crop. Certain clonal apple rootstocks were recognized for their...

  14. 40 CFR Appendix A to Subpart IIIi... - States With Approved State Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in Units A Appendix A to Subpart IIII of Part...) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Opt-in... Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in Units 1. The following States have...

  15. 40 CFR Appendix A to Subpart IIIi... - States With Approved State Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in Units A Appendix A to Subpart IIII of Part...) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Opt-in... Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in Units 1. The following States have...

  16. 40 CFR Appendix A to Subpart IIIi... - States With Approved State Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in Units A Appendix A to Subpart IIII of Part...) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Opt-in... Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in Units 1. The following States have...

  17. 40 CFR Appendix A to Subpart IIIi... - States With Approved State Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in Units A Appendix A to Subpart IIII of Part...) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Opt-in... Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in Units 1. The following States have...

  18. 40 CFR Appendix A to Subpart IIIi... - States With Approved State Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in Units A Appendix A to Subpart IIII of Part...) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Opt-in... Implementation Plan Revisions Concerning CAIR NOX Ozone Season Opt-in Units 1. The following States have...

  19. Overexpressing MhNPR1 in transgenic Fuji apples enhances resistance to apple powdery mildew.

    PubMed

    Chen, Xiu-Kong; Zhang, Ji-Yu; Zhang, Zhen; Du, Xiao-Li; Du, Bei-Bei; Qu, Shen-Chun

    2012-08-01

    Fuji is susceptible to fungal diseases like apple powdery mildew. Non-expressor of pathogenesis-related gene 1 (NPR1) plays a key role in regulating salicylic acid (SA)-mediated systemic acquired resistance (SAR). Previous studies show that overexpressing the Malus hupehensis-derived NPR1 (MhNPR1) gene in tobacco induces the transcript expression of pathogenesis-related genes (PRs) and resistance to the fungus Botrytis cinerea. In this study we introduced the MhNPR1 gene into the 'Fuji' apple via Agrobacterium-mediated transformation. Four transgenic apple lines were verified by PCR and RT-PCR. The semi-quantitative RT-PCR results showed that transcript overexpression of the MhNPR1 gene induced the expression of MdPRs and MdMLO genes known to interact with powdery mildew. Furthermore, the transgenic apple plants resisted infection by apple powdery mildew better than the wild-type plants. As a result, transcript overexpression of the MhNPR1 gene induced SAR and enhanced the Fuji apple's resistance to fungal disease.

  20. AL Amyloidosis

    PubMed Central

    2012-01-01

    Definition of the disease AL amyloidosis results from extra-cellular deposition of fibril-forming monoclonal immunoglobulin (Ig) light chains (LC) (most commonly of lambda isotype) usually secreted by a small plasma cell clone. Most patients have evidence of isolated monoclonal gammopathy or smoldering myeloma, and the occurrence of AL amyloidosis in patients with symptomatic multiple myeloma or other B-cell lymphoproliferative disorders is unusual. The key event in the development of AL amyloidosis is the change in the secondary or tertiary structure of an abnormal monoclonal LC, which results in instable conformation. This conformational change is responsible for abnormal folding of the LC, rich in β leaves, which assemble into monomers that stack together to form amyloid fibrils. Epidemiology AL amyloidosis is the most common type of systemic amyloidois in developed countries with an estimated incidence of 9 cases/million inhabitant/year. The average age of diagnosed patients is 65 years and less than 10% of patients are under 50. Clinical description The clinical presentation is protean, because of the wide number of tissues or organs that may be affected. The most common presenting symptoms are asthenia and dyspnoea, which are poorly specific and may account for delayed diagnosis. Renal manifestations are the most frequent, affecting two thirds of patients at presentation. They are characterized by heavy proteinuria, with nephrotic syndrome and impaired renal function in half of the patients. Heart involvement, which is present at diagnosis in more than 50% of patients, leading to restrictive cardiopathy, is the most serious complication and engages prognosis. Diagnostic methods The diagnosis relies on pathological examination of an involved site showing Congo red-positive amyloid deposits, with typical apple-green birefringence under polarized light, that stain positive with an anti-LC antibody by immunohistochemistry and/or immunofluorescence. Due to the

  1. OptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strains

    PubMed Central

    2010-01-01

    Background Computational modeling and analysis of metabolic networks has been successful in metabolic engineering of microbial strains for valuable biochemical production. Limitations of currently available computational methods for metabolic engineering are that they are often based on reaction deletions rather than gene deletions and do not consider the regulatory networks that control metabolism. Due to the presence of multi-functional enzymes and isozymes, computational designs based on reaction deletions can sometimes result in strategies that are genetically complicated or infeasible. Additionally, strains might not be able to grow initially due to regulatory restrictions. To overcome these limitations, we have developed a new approach (OptORF) for identifying metabolic engineering strategies based on gene deletion and overexpression. Results Here we propose an effective method to systematically integrate transcriptional regulatory networks and metabolic networks. This allows for the formulation of linear optimization problems that search for metabolic and/or regulatory perturbations that couple biomass and biochemical production, thus proposing adaptive evolutionary strain designs. Using genome-scale models of Escherichia coli, we have implemented the OptORF algorithm (which considers gene deletions and transcriptional regulation) and compared its metabolic engineering strategies for ethanol production to those found using OptKnock (which considers reaction deletions). Our results found that the reaction-based strategies often require more gene deletions to remove the identified reactions (2 more genes than reactions), and result in lethal growth phenotypes when transcriptional regulation is considered (162 out of 200 cases). Finally, we present metabolic engineering strategies for producing ethanol and higher alcohols (e.g. isobutanol) in E. coli using our OptORF approach. We have found common genetic modifications such as deletion of pgi and overexpression

  2. Codon-optimized Human Sodium Iodide Symporter (opt-hNIS) as a Sensitive Reporter and Efficient Therapeutic Gene

    PubMed Central

    Kim, Young-Hwa; Youn, Hyewon; Na, Juri; Hong, Kee-Jong; Kang, Keon Wook; Lee, Dong Soo; Chung, June-Key

    2015-01-01

    To generate a more efficient in vivo reporter and therapeutic gene, we optimized the coding sequence of the human sodium/iodide symporter (NIS) gene by replacing NIS DNA codons from wild type to new codons having the highest usage in human gene translation. The Codon Adaptation Index (CAI), representing the number of codons effective for human expression, was much improved (0.79 for hNIS, 0.97 for opt-hNIS). Both wild-type (hNIS) and optimized human NIS (opt-hNIS) were cloned into pcDNA3.1 and pMSCV vectors for transfection. Various cancer cell lines such as thyroid (TPC-1, FRO, B-CPAP), breast (MDA-MB-231), liver (Hep3B), cervical (HeLa), and glioma (U87MG) were transfected with pcDNA3.1/hNIS or pcDNA3.1/opt-hNIS. 125I uptake by opt-hNIS-expressing cells was 1.6 ~ 2.1 times higher than uptake by wild-type hNIS-expressing cells. Stable cell lines were also established by retroviral transduction using pMSCV/hNIS or pMSCV/opt-hNIS, revealing higher NIS protein levels and 125I uptake in opt-hNIS-expressing cells than in hNIS-expressing cells. Moreover, scintigraphic images from cell plates and mouse xenografts showed stronger signals from opt-hNIS-expressing cells than hNIS-expressing cells, and radioactivity uptake by opt-hNIS-expressing tumors was 2.3-fold greater than that by hNIS-expressing tumors. To test the efficacy of radioiodine therapy, mouse xenograft models were established with cancer cells expressing hNIS or opt-hNIS. 131I treatment reduced tumor sizes of hNIS- and opt-hNIS-expressing tumors to 0.57- and 0.27- fold, respectively, compared to their sizes before therapy, suggesting an improved therapeutic effect of opt-hNIS. In summary, this study shows that codon optimization strongly increases hNIS protein levels and radioiodine uptake, thus supporting opt-hNIS as a more sensitive reporter and efficient therapeutic gene. PMID:25553100

  3. Transcriptomics Analysis of Apple Leaves in Response to Alternaria alternata Apple Pathotype Infection

    PubMed Central

    Zhu, Longming; Ni, Weichen; Liu, Shuai; Cai, Binhua; Xing, Han; Wang, Sanhong

    2017-01-01

    Alternaria blotch disease of apple (Malus × domestica Borkh.), caused by the apple pathotype of Alternaria alternata, is one of the most serious fungal diseases to affect apples. To develop an understanding of how apples respond to A. alternata apple pathotype (AAAP) infection, we examined the host transcript accumulation over the period between 0 and 72 h post AAAP inoculation. Large-scale gene expression analysis was conducted of the compatible interaction between “Starking Delicious” apple cultivar and AAAP using RNA-Seq and digital gene expression (DGE) profiling methods. Our results show that a total of 9080 differentially expressed genes (DEGs) were detected (>two-fold and FDR < 0.001) by RNA-Seq. During the early phase of infection, 12 h post inoculation (HPI), AAAP exhibited limited fungal development and little change in the transcript accumulation status (950 DEGs). During the intermediate phase of infection, the period between 18 and 36 HPI, increased fungal development, active infection, and increased transcript accumulation were detected (4111 and 3838 DEGs detected at each time point, respectively). The majority of DEGs were detected by 72 HPI, suggesting that this is an important time point in the response of apples' AAAP infection. Subsequent gene ontology (GO) and pathway enrichment analyses showed that DEGs are predominately involved in biological processes and metabolic pathways; results showed that almost gene associated with photosynthesis, oxidation-reduction were down-regulated, while transcription factors (i.e., WRKY, MYB, NAC, and Hsf) and DEGs involved in cell wall modification, defense signaling, the synthesis of defense-related metabolites, including pathogenesis-related (PRs) genes and phenylpropanoid/cyanoamino acid /flavonoid biosynthesis, were activated during this process. Our study also suggested that the cell wall defensive vulnerability and the down-regulation of most PRs and HSP70s in “Starking Delicious” following AAAP

  4. Combination of Chaotic Neurodynamics with the 2-opt Algorithm to Solve Traveling Salesman Problems

    NASA Astrophysics Data System (ADS)

    Hasegawa, M.; Ikeguchi, T.; Aihara, K.

    1997-09-01

    We propose a novel approach for combinatorial optimization problems. For solving the traveling salesman problems, we combine chaotic neurodynamics with heuristic algorithm. We select the heuristic algorithm of 2-opt as a basic part, because it is well understood that this simple algorithm is very effective for the traveling salesman problems. Although the conventional approaches with chaotic neurodynamics were only applied to such very small problems as 10 cities, our method exhibits higher performance for larger size problems with the order of 102.

  5. OptCircuit: An optimization based method for computational design of genetic circuits

    PubMed Central

    Dasika, Madhukar S; Maranas, Costas D

    2008-01-01

    Background Recent years has witnessed an increasing number of studies on constructing simple synthetic genetic circuits that exhibit desired properties such as oscillatory behavior, inducer specific activation/repression, etc. It has been widely acknowledged that that task of building circuits to meet multiple inducer-specific requirements is a challenging one. This is because of the incomplete description of component interactions compounded by the fact that the number of ways in which one can chose and interconnect components, increases exponentially with the number of components. Results In this paper we introduce OptCircuit, an optimization based framework that automatically identifies the circuit components from a list and connectivity that brings about the desired functionality. Multiple literature sources are used to compile a comprehensive compilation of kinetic descriptions of promoter-protein pairs. The dynamics that govern the interactions between the elements of the genetic circuit are currently modeled using deterministic ordinary differential equations but the framework is general enough to accommodate stochastic simulations. The desired circuit response is abstracted as the maximization/minimization of an appropriately constructed objective function. Computational results for a toggle switch example demonstrate the ability of the framework to generate the complete list of circuit designs of varying complexity that exhibit the desired response. Designs identified for a genetic decoder highlight the ability of OptCircuit to suggest circuit configurations that go beyond the ones compatible with digital logic-based design principles. Finally, the results obtained from the concentration band detector example demonstrate the ability of OptCircuit to design circuits whose responses are contingent on the level of external inducer as well as pinpoint parameters for modification to rectify an existing (non-functional) biological circuit and restore

  6. 12 CFR Appendix C to Part 1022 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) Pt. 1022, App. C Appendix C to Part 1022—Model Forms for Opt-Out Notices a. Although use of the model... limit marketing offers, contact us : • By telephone: 1-(877) ###-#### • On the Web: www.—.com • By mail... the Web: www.—.com • By mail: Check the box and complete the form below, and send the form to: —Do...

  7. 12 CFR Appendix C to Part 334 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... POLICY FAIR CREDIT REPORTING Pt. 334, App. C Appendix C to Part 334—Model Forms for Opt-Out Notices a...: 1-877-###-#### • On the Web: www.—.com • By mail: Check the box and complete the form below, and... limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.—.com • By...

  8. 12 CFR Appendix C to Part 571 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPORTING Pt. 571, App. C Appendix C to Part 571—Model Forms for Opt-Out Notices a. Although use of the...: 1-877-###-#### • On the Web: www.---.com • By mail: Check the box and complete the form below, and... limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.---.com • By...

  9. 12 CFR Appendix C to Part 571 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REPORTING Pt. 571, App. C Appendix C to Part 571—Model Forms for Opt-Out Notices a. Although use of the...: 1-877-###-#### • On the Web: www.---.com • By mail: Check the box and complete the form below, and... limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.---.com • By...

  10. 12 CFR Appendix C to Part 571 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REPORTING Pt. 571, App. C Appendix C to Part 571—Model Forms for Opt-Out Notices a. Although use of the...: 1-877-###-#### • On the Web: www.---.com • By mail: Check the box and complete the form below, and... limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.---.com • By...

  11. 12 CFR Appendix C to Part 334 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... POLICY FAIR CREDIT REPORTING Pt. 334, App. C Appendix C to Part 334—Model Forms for Opt-Out Notices a...: 1-877-###-#### • On the Web: www.---.com • By mail: Check the box and complete the form below, and... limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.---.com • By...

  12. 12 CFR Appendix C to Part 41 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Pt. 41, App. C Appendix C to Part 41—Model Forms for Opt-Out Notices a. Although use of the model...: 1-877-###-#### • On the Web: www.—.com • By mail: Check the box and complete the form below, and... limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.—.com • By...

  13. 12 CFR Appendix C to Part 334 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... POLICY FAIR CREDIT REPORTING Pt. 334, App. C Appendix C to Part 334—Model Forms for Opt-Out Notices a...: 1-877-###-#### • On the Web: www.---.com • By mail: Check the box and complete the form below, and... limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.---.com • By...

  14. 12 CFR Appendix C to Part 1022 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) Pt. 1022, App. C Appendix C to Part 1022—Model Forms for Opt-Out Notices a. Although use of the model... limit marketing offers, contact us : • By telephone: 1-(877) ###-#### • On the Web: www.—.com • By mail... the Web: www.—.com • By mail: Check the box and complete the form below, and send the form to: —Do...

  15. 12 CFR Appendix C to Part 334 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... POLICY FAIR CREDIT REPORTING Pt. 334, App. C Appendix C to Part 334—Model Forms for Opt-Out Notices a...: 1-877-###-#### • On the Web: www.---.com • By mail: Check the box and complete the form below, and... limit marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.---.com • By...

  16. 12 CFR Appendix C to Part 717 - Model Forms for Opt-Out Notices

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... FAIR CREDIT REPORTING Pt. 717, App. C Appendix C to Part 717—Model Forms for Opt-Out Notices a... marketing offers, contact us : • By telephone: 1-877-###-#### • On the Web: www.—.com • By mail: Check the... the Web: www.—.com • By mail: Check the box and complete the form below, and send the form to: _Do...

  17. 16 CFR 680.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... REPORTING ACT AFFILIATE MARKETING § 680.23 Contents of opt-out notice; consolidated and equivalent notices... “all of the ABC companies,” “the ABC banking, credit card, insurance, and securities companies,” or by... “all of the ABC companies,” “the ABC banking, credit card, insurance, and securities companies,” or...

  18. Metaphors of organ donation, social representations of the body and the opt-out system.

    PubMed

    Lauri, Mary Anne

    2009-11-01

    Organ donation is the only available treatment for end-stage failure of organs such as liver, lung, and heart and therefore increasing the number of organ donors is a priority for most countries. One measure that could be taken by a country to increase the number of organ transplants is to introduce the opt-out system of organ donation. Public opinion is divided on this issue and policy makers need to tread with caution before introducing legislation. This paper proposes that understanding the social representations the public has of organ donation is important in taking the right policy decisions. We propose here that an in-depth study of the views held by people on the issue is essential in this regard and that this can best be done by investigating the metaphors people use to describe organ donation, interpreted within the theory of social representation. In this study, the social representations of organ donation were investigated through five focus groups with 57 participants living in Malta. Analysis of the transcriptions of these focus groups yielded pertinent issues related to organ donation. Moreover, metaphors of organ donations and how these were related to social representations of the body and attitudes towards the opt-out system are discussed. It is being suggested that these findings could be of relevance to the present discussion on the opt-out system in the UK and in other countries.

  19. Genetic Diversity of a Natural Population of Apple stem pitting virus Isolated from Apple in Korea.

    PubMed

    Yoon, Ju Yeon; Joa, Jae Ho; Choi, Kyung San; Do, Ki Seck; Lim, Han Cheol; Chung, Bong Nam

    2014-06-01

    Apple stem pitting virus (ASPV), of the Foveavirus genus in the family Betaflexiviridae, is one of the most common viruses of apple and pear trees. To examine variability of the coat protein (CP) gene from ASPV, eight isolates originating from 251 apple trees, which were collected from 22 apple orchards located in intensive apple growing areas of the North Gyeongsang and North Jeolla Provinces in Korea, were sequenced and compared. The nucleotide sequence identity of the CP gene of eight ASPV isolates ranged from 77.0 to 97.0%, while the amino acid sequence identity ranged from 87.7 to 98.5%. The N-terminal region of the viral CP gene was highly variable, whereas the C-terminal region was conserved. Genetic algorithm recombination detection (GARD) and single breakpoint recombination (SBP) analyses identified base substitutions between eight ASPV isolates at positions 54 and 57 and position 771, respectively. GABranch analysis was used to determine whether the eight isolates evolved due to positive selection. All values in the GABranch analysis showed a ratio of substitution rates at non-synonymous and synonymous sites (dNS/dS) below 1, suggestive of strong negative selection forces during ASPV CP history. Although negative selection dominated CP evolution in the eight ASPV isolates, SLAC and FEL tests identified four possible positive selection sites at codons 10, 22, 102, and 158. This is the first study of the ASPV genome in Korea.

  20. Ethylene binding site affinity in ripening apples

    SciTech Connect

    Blankenship, S.M. . Dept. of Horticultural Science); Sisler, E.C. )

    1993-09-01

    Scatchard plots for ethylene binding in apples (Malus domestica Borkh.), which were harvested weekly for 5 weeks to include the ethylene climacteric rise, showed C[sub 50] values (concentration of ethylene needed to occupy 50% of the ethylene binding sites) of 0.10, 0.11, 0.34, 0.40, and 0.57 [mu]l ethylene/liter[sup [minus]1], respectively, for each of the 5 weeks. Higher ethylene concentrations were required to saturate the binding sites during the climacteric rise than at other times. Diffusion of [sup 14]C-ethylene from the binding sites was curvilinear and did not show any indication of multiple binding sites. Ethylene was not metabolized by apple tissue.

  1. Integrated pest management of "Golden Delicious" apples.

    PubMed

    Simončič, A; Stopar, M; Velikonja Bolta, Š; Bavčar, D; Leskovšek, R; Baša Česnik, H

    2015-01-01

    Monitoring of plant protection product (PPP) residues in "Golden Delicious" apples was performed in 2011-2013, where 216 active substances were analysed with three analytical methods. Integrated pest management (IPM) production and improved IPM production were compared. Results were in favour of improved IPM production. Some active compounds determined in IPM production (boscalid, pyraclostrobin, thiacloprid and thiametoxam) were not found in improved IPM production. Besides that, in 2011 and 2012, captan residues were lower in improved IPM production. Risk assessment was also performed. Chronic exposure of consumers was low in general, but showed no major differences for IPM and improved IPM production for active substances determined in both types of production. Analytical results were compared with the European Union report of 2010 where 1.3% of apple samples exceeded maximum residue levels (MRLs), while MRL exceedances were not observed in this survey.

  2. Response time accuracy in Apple Macintosh computers.

    PubMed

    Neath, Ian; Earle, Avery; Hallett, Darcy; Surprenant, Aimée M

    2011-06-01

    The accuracy and variability of response times (RTs) collected on stock Apple Macintosh computers using USB keyboards was assessed. A photodiode detected a change in the screen's luminosity and triggered a solenoid that pressed a key on the keyboard. The RTs collected in this way were reliable, but could be as much as 100 ms too long. The standard deviation of the measured RTs varied between 2.5 and 10 ms, and the distributions approximated a normal distribution. Surprisingly, two recent Apple-branded USB keyboards differed in their accuracy by as much as 20 ms. The most accurate RTs were collected when an external CRT was used to display the stimuli and Psychtoolbox was able to synchronize presentation with the screen refresh. We conclude that RTs collected on stock iMacs can detect a difference as small as 5-10 ms under realistic conditions, and this dictates which types of research should or should not use these systems.

  3. UV inactivation of bacteria in apple cider.

    PubMed

    Geveke, David J

    2005-08-01

    Apple cider, inoculated with Escherichia coli and Listeria innocua, was processed using a simple UV apparatus. The apparatus consisted of a low-pressure mercury lamp surrounded by a coil of UV transparent tubing. Cider was pumped through the tubing at flow rates of 27 to 83 ml/min. The population of E. coli K-12 was reduced by 3.4 +/- 0.3 log after being exposed for 19 s at a treatment temperature of 25 degrees C. The population of L. innocua, which was more resistant to UV, was reduced by 2.5 +/- 0.1 log after being exposed for 58 s. The electrical energy for the process was 34 J/ml and is similar to that for conventional thermal processing. UV processing has the potential to improve the safety and extend the shelf life of apple cider.

  4. Parental opinions regarding an opt-out consent process for inpatient pediatric prospective observational research in the US

    PubMed Central

    Fernandes, Danielle M; Roland, Allison P; Morris, Marilyn C

    2017-01-01

    Objective To explore parental opinions regarding opt-out consent for inpatient pediatric prospective observational research in the US. Study design A series of handouts describing hypothetical observational research studies with opt-out consent were reviewed by parents of hospitalized children. A verbal survey explored parental opinions about the proposed consent process. Results A total of 166 parents reviewed the handout and completed the survey. Only 2/166 parents (1.2%) objected to the study described and another 10 (6.0%) cited concern about the privacy of their child’s medical information. A total of 157 parents were asked “Is it okay to tell you about this kind of research using this handout?” – 116 (74%) responded positively, 19 (12%) responded negatively, and 21 (13%) made an indeterminate or neutral response. When parents were asked to recommend a specific consent approach for observational research, 86 (52%) chose an opt-in approach, 54 (33%) chose opt-out, and 25 (15%) chose “no consent needed”. There were no significant associations between parental preferences and whether the child was admitted to the intensive care unit vs. pediatric ward, and no significant difference found based on type of handout reviewed (generic vs. study-specific). Conclusion Few parents voiced objection to a hypothetical opt-out consent process for inpatient pediatric prospective observational research. When asked to recommend a specific consent approach, though, approximately half chose an opt-in approach. These data suggest that an opt-out consent process for observational inpatient research is likely to be acceptable to parents, but assessment of an opt-out consent process in a real-world setting is needed. PMID:28176926

  5. Evaluation of apple juice quality using spectral fluorescence signatures.

    PubMed

    Poryvkina, L; Tsvetkova, N; Sobolev, I

    2014-01-01

    In current work the method of in vivo evaluation of apple juice degree of naturalness based on Spectral Fluorescence Signature (SFS) is proposed. SFS spectra of intact apple juice were measured as excitation-emission matrix by specially designed compact spectrofluorimeter with front-face optical layout - Instant Screener Compact (LDI AS, Estonia). The data were analysed using PCA method with a view to evaluate the information of polyphenol's content in different commercial juices. Results of PCA analysis have shown a clear separation of juice reconstituted from concentrate, unclarified pasteurised juice and personally squeezed apple juice at the two dimensional PCs space. For implementation of apple juice analysis into spectrofluorimeter software the k-Nearest Neighbor (kNN) Search technique was used. The implemented model was tested using 19 different samples of apple juice. Results of test demonstrate that SFS-PCA-kNN method can provide quick nondestructive analysis of naturalness degree of commercial apple juice.

  6. Sustainability of three apple production systems.

    PubMed

    Reganold, J P; Glover, J D; Andrews, P K; Hinman, H R

    2001-04-19

    Escalating production costs, heavy reliance on non-renewable resources, reduced biodiversity, water contamination, chemical residues in food, soil degradation and health risks to farm workers handling pesticides all bring into question the sustainability of conventional farming systems. It has been claimed, however, that organic farming systems are less efficient, pose greater health risks and produce half the yields of conventional farming systems. Nevertheless, organic farming became one of the fastest growing segments of US and European agriculture during the 1990s. Integrated farming, using a combination of organic and conventional techniques, has been successfully adopted on a wide scale in Europe. Here we report the sustainability of organic, conventional and integrated apple production systems in Washington State from 1994 to 1999. All three systems gave similar apple yields. The organic and integrated systems had higher soil quality and potentially lower negative environmental impact than the conventional system. When compared with the conventional and integrated systems, the organic system produced sweeter and less tart apples, higher profitability and greater energy efficiency. Our data indicate that the organic system ranked first in environmental and economic sustainability, the integrated system second and the conventional system last.

  7. Getting Started with AppleWorks Data Base. First Edition.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This manual is a hands-on teaching tool for beginning users of the AppleWorks database software. It was developed to allow Apple IIGS users who are generally familiar with their machine and its peripherals to build a simple AppleWorks database file using version 2.0 or 2.1 of the program, and to store, print, and manipulate the file. The materials…

  8. The Venturia Apple Pathosystem: Pathogenicity Mechanisms and Plant Defense Responses

    PubMed Central

    Jha, Gopaljee; Thakur, Karnika; Thakur, Priyanka

    2009-01-01

    Venturia inaequalis is the causal agent of apple scab, a devastating disease of apple. We outline several unique features of this pathogen which are useful for molecular genetics studies intended to understand plant-pathogen interactions. The pathogenicity mechanisms of the pathogen and overview of apple defense responses, monogenic and polygenic resistance, and their utilization in scab resistance breeding programs are also reviewed. PMID:20150969

  9. Oviposition preference of Oriental fruit moth [Grapholita molesta (Busck), Lepidoptera: Tortricidae] for apple cultivars

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Oviposition preferences and apple cultivar selection by fruit pests may impact integrated pest management in apple orchards. Experiments were conducted to study oviposition preferences of Oriental fruit moth ( Grapholita molesta [Busck], Lepidoptera: Tortricidae) on ten commercially important apple ...

  10. Developing Data Base Files Using the AppleWorks Data Base Subprogram and Apple IIe or GS Computers.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    Developed around the technology of the Apple duodisk drive, five and one-fourth inch floppy disks, and the 1.3 version of the AppleWorks program, this manual is designed for use as a "how to" training device in developing database files. The guide is meant to be used with Apple IIe or IIGS computers which have a duodisk or two disk…

  11. The kids at Hamilton Elementary School: Purposes and practices for co-opting science

    NASA Astrophysics Data System (ADS)

    Ortiz, Loaiza

    The purpose of this study was to explore youth's purposes and motivations for engaging in science through the lens of science practices. The construct of science practices allowed me to see science in youths' lives in a holistic way, shaped by social, political, historical, economic and cultural forces. The framework for understanding urban youths' science practices is grounded in the intersections of critical and feminist theory, sociocultural learning theories, especially as applied in research in urban science education, and recent work in critical literacy studies. As I explored the answers to my research questions---(1) When 5th grade youth, living in predominantly Latino communities struggling with urban poverty, engage in science how and why do they co-opt science in ways that result in changes in participation in science? (2) What are the science practices that facilitate youths' coopting of science? And how are those practices framed by context (school, out-of-school), content (LiFE curriculum), and funds of knowledge? (3) In what ways are science practices expressions of youths' scientific literacy? And (4) In what ways do youth use science practices as tools for expressing identities and agency?---I engaged in feminist ethnography with embedded case studies. Data were collected in 2004 in school and in out of school settings. I recorded numerous informal conversations, interviews, and observations both during after-school and students' regular science and non-science classes. Findings describe how and why students co-opted science for purposes that make sense for their lives. These purposes included gaining and activating resources, building and maintaining social relationships, bridging home and school knowledge, positioning themselves with authority, and constructing science identities. Findings also explored what practices facilitated youth's co-opting of science. I highlighted three practices: making ideas public, storytelling and prioritizing and

  12. Vanishing vaccinations: why are so many Americans opting out of vaccinating their children?

    PubMed

    Calandrillo, Steve P

    2004-01-01

    Vaccinations against life-threatening diseases are one of the greatest public health achievements in history. Literally millions of premature deaths have been prevented, and countless more children have been saved from disfiguring illness. While vaccinations carry unavoidable risks, the medical, social and economic benefits they confer have led all fifty states to enact compulsory childhood vaccination laws to stop the spread of preventable diseases. Today, however, vaccines are becoming a victim of their success--many individuals have never witnessed the debilitating diseases that vaccines protect against, allowing complacency toward immunization requirements to build. Antivaccination sentiment is growing fast in the United States, in large part due to the controversial and hotly disputed link between immunizations and autism. The internet worsens fears regarding vaccination safety, as at least a dozen websites publish alarming information about the risks of vaccines. Increasing numbers of parents are refusing immunizations for their children and seeking legally sanctioned exemptions instead, apparently fearing vaccines more than the underlying diseases that they protect against. A variety of factors are at play: religious and philosophical beliefs, freedom and individualism, misinformation about risk, and overperception of risk. State legislatures and health departments now face a difficult challenge: respecting individual rights and freedoms while also safeguarding the public welfare. Nearly all states allow vaccination exemptions for religious reasons and a growing number provide "philosophical" opt-outs as well. However, in all but a handful of jurisdictions, neither objection is seriously documented or verified. Often, the law requires a parent to do no more than simply check a box indicating she does not wish her child to receive immunizations. The problem is exacerbated by financial incentives schools have to encourage students to opt out of vaccinations

  13. Apples in the Apple Library--How One Library Took a Byte.

    ERIC Educational Resources Information Center

    Ertel, Monica

    1983-01-01

    Summarizes automation of a specialized library at Apple Computer, Inc., describing software packages chosen for the following functions: word processing/text editing; cataloging and circulation; reference; and in-house databases. Examples of each function and additional sources of information on software and equipment mentioned in the article are…

  14. Reading Michael Apple--The Sociological Imagination at Work

    ERIC Educational Resources Information Center

    Ball, Stephen J.

    2007-01-01

    This article discusses Michael Apple's contribution to the sociology of education and education policy analysis and the politics of education. It focuses on ways of "reading" Apple as an intellectual and an activist and looks at the trajectory of his work over a long and illustrious career.

  15. Chapter 11. Quality evaluation of apple by computer vision

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apple is one of the most consumed fruits in the world, and there is a critical need for enhanced computer vision technology for quality assessment of apples. This chapter gives a comprehensive review on recent advances in various computer vision techniques for detecting surface and internal defects ...

  16. Interview with Michael Apple: The Biography of a Public Intellectual

    ERIC Educational Resources Information Center

    Peters, Michael A.

    2015-01-01

    Michael W. Apple is the John Bascom Professor of Curriculum and Instruction and Educational Policy Studies in the Departments of Curriculum and Instruction (CI) and Educational Policy Studies (EPS) at the University of Wisconsin-Madison School of Education where he has taught since 1970. Michael Apple is one of the foremost educational theorists…

  17. Sugar apple emerges as tempting treat for Florida Growers

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Sugar Apple, Annona squamosa, is described as a potential alternative crop for the Florida east coast. Sugar Apple is highly productive of fruit on bushes from seed beginning at about 1-2 years of age, and produces a very flavorful and highly sought after tropical fruit. Several cultivars of Sug...

  18. Apple anthracnose canker life cycle and disease cycle

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apple anthracnose [caused by Neofabraea malicorticis (H.S. Jacks) anamorph Cryptosporiopsis curvispora (Peck)] is a fungal disease that impacts apple production. The pathogen produces cankers on trees as well as a rot on the fruit known as ‘Bull’s-eye rot’. The cankers cause severe damage to trees...

  19. Morphological and chemical characterization of the kei apple (Dovyalis spp)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Dovyalis (Tropical apple) is an exotic fruit originated in Africa, reddish-orange color and high acidity. Tropical apricot or Kei apple (Dovyalis hebecarpa X D. abyssinica) P.I. 112086, is a natural cross which resulted from a mixed planting of D. hebecarpa and D. abyssinica at the Subtropical Horti...

  20. Apple juice greatly reduces systemic exposure to atenolol

    PubMed Central

    Jeon, Hyewon; Jang, In-Jin; Lee, SeungHwan; Ohashi, Kyoichi; Kotegawa, Tsutomu; Ieiri, Ichiro; Cho, Joo-Youn; Yoon, Seo Hyun; Shin, Sang-Goo; Yu, Kyung-Sang; Lim, Kyoung Soo

    2013-01-01

    AIM Fruit juice reduces the plasma concentrations of several β-adrenoceptor blockers, likely by inhibiting OATP2B1-mediated intestinal absorption. The aim of this study was to investigate the effects of apple juice on the pharmacokinetics of atenolol. METHODS Twelve healthy Korean volunteers with genotypes of SLCO2B1 c.1457C> T (*1/*1 (n= 6) and *3/*3 (n= 6)) were enrolled in this study. In a three-phase, one-sequence crossover study, the pharmacokinetics (PK) of atenolol was evaluated after administration of 50 mg atenolol. Subjects received atenolol with either 300 ml water, 1200 ml apple juice or 600 ml apple juice. RESULTS Apple juice markedly reduced the systemic exposure to atenolol. The geometric mean ratios (95% confidence intervals) of apple juice : water were 0.18 (0.13, 0.25, 1200 ml) and 0.42 (0.30, 0.59, 600 ml) for the AUC(0,tlast). In this study, the PK parameters of atenolol responded in a dose-dependent manner to apple juice. CONCLUSIONS Apple juice markedly reduced systemic exposure to atenolol. The genetic variation of SLCO2B1 c.1457C>T had a minimal effect on the pharmacokinetics of atenolol when the drug was administered with water or apple juice. PMID:22574741

  1. Cytology of infection of apple leaves by Diplocarpon mali

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Diplocarpon mali, the causal agent of Marssonina leaf blotch of apple, causes severe defoliation during the growing season. Little information is available on the mode of infection and infection process. In this study, the infection strategies of D. mali in apple leaves were investigated using fluor...

  2. Formatting Data Disks for Use with the Apple IIe Computer.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This step-by-step guide to formatting disks using the AppleWorks software on the Apple IIe computer covers (1) loading the program; (2) formatting the disk; (3) volume naming; and (4) exiting the format options. Eleven sample screen displays illustrate the steps. (MES)

  3. Genome to phenome mapping in apple using historical data

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apple (Malus domestica) is one of the world’s most valuable fruit crops. Its large size and long juvenile phase make it a particularly promising candidate for marker-assisted selection (MAS). However, advances in MAS in apple have been limited by a lack of phenotype and genotype data from sufficien...

  4. Unraveling apple fruit metabolism: Storage management opportunities and beyond

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Apple fruit has become a staple fruit commodity in many markets worldwide, making year-round availability crucial to retail chains. Consequently, apple storage practices have become increasingly sophisticated to meet rising quality expectations of fresh taste and a blemish free appearance. Modern ...

  5. Apple-products phytochemicals and processing: a review.

    PubMed

    Soler, Carla; Soriano, José M; Mañes, Jordi

    2009-05-01

    Epidemiological studies have linked the consumption of apples with reduced risk of some cancers, cardiovascular disease, asthma, and diabetes. Extensive research exists on apples and the health benefits of their beverages and phytochemicals. The purpose of this paper is to review the most recent literature in this area focusing on phytochemicals, phytochemical bioavailability and antioxidant behavior.

  6. Sources and availability of Sphaeropsis pyriputrescens inoculum in apple orchards

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sphaeropsis pyriputrescens (SP) is the cause of Sphaeropsis rot, a recently reported postharvest fruit rot disease of apple. Infections of apple fruit by the fungus occur in the orchard, and symptoms develop during storage or in the market. SP also is the cause of a twig dieback and canker disease o...

  7. Classworks: AppleWorks for the Classroom. Second Edition.

    ERIC Educational Resources Information Center

    Thomas, Rick

    This book provides a brief and succinct introduction to AppleWorks and is designed for use by teachers who are already familiar with the three AppleWorks tools: the word processor, the database, and the spreadsheet. "Classworks" (developed for grades 8 and 9) emphasizes computer work in which the teacher serves as troubleshooter,…

  8. Gene expression profiles of auxin metabolism in maturing apple fruit

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Variation exists among apple genotypes in fruit maturation and ripening patterns that influences at-harvest fruit firmness and postharvest storability. Based on the results from our previous large-scale transcriptome profiling on apple fruit maturation and well-documented auxin-ethylene crosstalk, t...

  9. Apple peels as a value-added food ingredient.

    PubMed

    Wolfe, Kelly L; Liu, Rui Hai

    2003-03-12

    There is some evidence that chronic diseases, such as cancer and cardiovascular disease, may occur as a result of oxidative stress. Apple peels have high concentrations of phenolic compounds and may assist in the prevention of chronic diseases. Millions of pounds of waste apple peels are generated in the production of applesauce and canned apples in New York State each year. We proposed that a valuable food ingredient could be made using the peels of these apples if they could be dried and ground to a powder without large losses of phytochemicals. Rome Beauty apple peels were treated with citric acid dips, ascorbic acid dips, and blanches before being oven-dried at 60 degrees C. Only blanching treatments greatly preserved the phenolic compounds, and peels blanched for 10 s had the highest total phenolic content. Rome Beauty apple peels were then blanched for 10 s and dried under various conditions (oven-dried at 40, 60, or 80 degrees C, air-dried, or freeze-dried). The air-dried and freeze-dried apple peels had the highest total phenolic, flavonoid, and anthocyanin contents. On a fresh weight basis, the total phenolic and flavonoid contents of these samples were similar to those of the fresh apple peels. Freeze-dried peels had a lower water activity than air-dried peels on a fresh weight basis. The optimal processing conditions for the ingredient were blanching for 10s and freeze-drying. The process was scaled up, and the apple peel powder ingredient was characterized. The total phenolic content was 3342 +/- 12 mg gallic acid equivalents/100 g dried peels, the flavonoid content was 2299 +/- 52 mg catechin equivalents/100 g dried peels, and the anthocyanin content was 169.7 +/- 1.6 mg cyanidin 3-glucoside equivalents/100 g dried peels. These phytochemical contents were a significantly higher than those of the fresh apple peels if calculated on a fresh weight basis (p < 0.05). The apple peel powder had a total antioxidant activity of 1251 +/- 56 micromol vitamin C

  10. A voluntary deductible in health insurance: the more years you opt for it, the lower your premium?

    PubMed

    van Winssen, K P M; van Kleef, R C; van de Ven, W P M M

    2017-03-01

    Adverse selection regarding a voluntary deductible (VD) in health insurance implies that insured only opt for a VD if they expect no (or few) healthcare expenses. This paper investigates two potential strategies to reduce adverse selection: (1) differentiating the premium to the duration of the contract for which the VD holds (ex-ante approach) and (2) differentiating the premium to the number of years for which insured have opted for a VD (ex-post approach). It can be hypothesized that premiums will decrease with the duration of the contract or the number of years for which insured have opted for a VD, providing an incentive to insured to opt for a deductible also in (incidental) years they expect relatively high expenses. To test this hypothesis, we examine which premium patterns would occur under these strategies using data on healthcare expenses and risk characteristics of over 750,000 insured from 6 years. Our results show that, under the assumptions made, only without risk equalization the premiums could decrease with the duration of the contract or the number of years for which insured have opted for a VD. With (sophisticated) risk equalization, decreasing premiums seem unfeasible, both under the ex-ante and ex-post approach. Given these findings, we are sceptical about the feasibility of these strategies to counteract adverse selection.

  11. A Real-Time Apple Grading System Using Multicolor Space

    PubMed Central

    2014-01-01

    This study was focused on the multicolor space which provides a better specification of the color and size of the apple in an image. In the study, a real-time machine vision system classifying apples into four categories with respect to color and size was designed. In the analysis, different color spaces were used. As a result, 97% identification success for the red fields of the apple was obtained depending on the values of the parameter “a” of CIE L*a*b*color space. Similarly, 94% identification success for the yellow fields was obtained depending on the values of the parameter y of CIE XYZ color space. With the designed system, three kinds of apples (Golden, Starking, and Jonagold) were investigated by classifying them into four groups with respect to two parameters, color and size. Finally, 99% success rate was achieved in the analyses conducted for 595 apples. PMID:24574880

  12. Alar and apples: newspapers, risk and media responsibility.

    PubMed

    Friedman, S M; Villamil, K; Suriano, R A; Egolf, B P

    1996-01-01

    During 1989, a major environmental and health risk issue, the spraying of Alar on apples, created a furor among the American people. After hearing charges from the Natural Resources Defense Council (NRDC) that eating Alar-laden apples significantly increased a child's risk of developing cancer, numbers of school districts dropped apples from their menus and parents poured apple juice down the drains. Apple sales plummeted. The NRDC's charges, which were disseminated by a well-planned and effective public relations campaign, brought counter-charges from the US environmental Protection Agency, which accused the NRDC of basing its study on poor data, among other things. The core of the dispute was in the risk figures and risk interpretations being used by each organization.

  13. OptForce: An Optimization Procedure for Identifying All Genetic Manipulations Leading to Targeted Overproductions

    PubMed Central

    Ranganathan, Sridhar; Suthers, Patrick F.; Maranas, Costas D.

    2010-01-01

    Computational procedures for predicting metabolic interventions leading to the overproduction of biochemicals in microbial strains are widely in use. However, these methods rely on surrogate biological objectives (e.g., maximize growth rate or minimize metabolic adjustments) and do not make use of flux measurements often available for the wild-type strain. In this work, we introduce the OptForce procedure that identifies all possible engineering interventions by classifying reactions in the metabolic model depending upon whether their flux values must increase, decrease or become equal to zero to meet a pre-specified overproduction target. We hierarchically apply this classification rule for pairs, triples, quadruples, etc. of reactions. This leads to the identification of a sufficient and non-redundant set of fluxes that must change (i.e., MUST set) to meet a pre-specified overproduction target. Starting with this set we subsequently extract a minimal set of fluxes that must actively be forced through genetic manipulations (i.e., FORCE set) to ensure that all fluxes in the network are consistent with the overproduction objective. We demonstrate our OptForce framework for succinate production in Escherichia coli using the most recent in silico E. coli model, iAF1260. The method not only recapitulates existing engineering strategies but also reveals non-intuitive ones that boost succinate production by performing coordinated changes on pathways distant from the last steps of succinate synthesis. PMID:20419153

  14. Differential Bees Flux Balance Analysis with OptKnock for In Silico Microbial Strains Optimization

    PubMed Central

    Choon, Yee Wen; Mohamad, Mohd Saberi; Deris, Safaai; Illias, Rosli Md.; Chong, Chuii Khim; Chai, Lian En; Omatu, Sigeru; Corchado, Juan Manuel

    2014-01-01

    Microbial strains optimization for the overproduction of desired phenotype has been a popular topic in recent years. The strains can be optimized through several techniques in the field of genetic engineering. Gene knockout is a genetic engineering technique that can engineer the metabolism of microbial cells with the objective to obtain desirable phenotypes. However, the complexities of the metabolic networks have made the process to identify the effects of genetic modification on the desirable phenotypes challenging. Furthermore, a vast number of reactions in cellular metabolism often lead to the combinatorial problem in obtaining optimal gene deletion strategy. Basically, the size of a genome-scale metabolic model is usually large. As the size of the problem increases, the computation time increases exponentially. In this paper, we propose Differential Bees Flux Balance Analysis (DBFBA) with OptKnock to identify optimal gene knockout strategies for maximizing the production yield of desired phenotypes while sustaining the growth rate. This proposed method functions by improving the performance of a hybrid of Bees Algorithm and Flux Balance Analysis (BAFBA) by hybridizing Differential Evolution (DE) algorithm into neighborhood searching strategy of BAFBA. In addition, DBFBA is integrated with OptKnock to validate the results for improving the reliability the work. Through several experiments conducted on Escherichia coli, Bacillus subtilis, and Clostridium thermocellum as the model organisms, DBFBA has shown a better performance in terms of computational time, stability, growth rate, and production yield of desired phenotypes compared to the methods used in previous works. PMID:25047076

  15. eCodonOpt: a systematic computational framework for optimizing codon usage in directed evolution experiments

    PubMed Central

    Moore, Gregory L.; Maranas, Costas D.

    2002-01-01

    We present a systematic computational framework, eCodonOpt, for designing parental DNA sequences for directed evolution experiments through codon usage optimization. Given a set of homologous parental proteins to be recombined at the DNA level, the optimal DNA sequences encoding these proteins are sought for a given diversity objective. We find that the free energy of annealing between the recombining DNA sequences is a much better descriptor of the extent of crossover formation than sequence identity. Three different diversity targets are investigated for the DNA shuffling protocol to showcase the utility of the eCodonOpt framework: (i) maximizing the average number of crossovers per recombined sequence; (ii) minimizing bias in family DNA shuffling so that each of the parental sequence pair contributes a similar number of crossovers to the library; and (iii) maximizing the relative frequency of crossovers in specific structural regions. Each one of these design challenges is formulated as a constrained optimization problem that utilizes 0–1 binary variables as on/off switches to model the selection of different codon choices for each residue position. Computational results suggest that many-fold improvements in the crossover frequency, location and specificity are possible, providing valuable insights for the engineering of directed evolution protocols. PMID:12034828

  16. Prevalence of Escherichia coli in apple cider manufactured in Connecticut.

    PubMed

    Dingman, D W

    1999-06-01

    Cider samples obtained from 11 cider mills operating in Connecticut during the 1997 to 1998 production season were tested for the presence of Escherichia coli. Cider production began in mid August and continued through March, with peak production in September and October. Of 314 cider samples tested, 11 (4%) were found to contain E. coli. Of the 11 mills, 6 (55%) tested positive for E. coli in the cider at least once during the production year. E. coli was first observed in cider samples produced in mid to late October and was not detected in samples made after January. A trend was observed for cider to decrease in acidity and increase in Brix (soluble sugars) throughout the production season. No correlation between pH and soluble sugars of cider and the presence of E. coli was detected. Eight mills used both dropped apples and tree-picked apples, whereas three mills used tree-picked apples only. The use of dropped apples in cider production began 5 weeks before the first detection of E. coli in cider. E. coli was isolated from cider samples produced using dropped apples and from samples produced using only tree-picked apples. No direct correlation between the use of dropped apples or tree-picked apples and the presence of E. coli in the cider was observed. An association between the time of apple harvest and the appearance of E. coli in cider was noted. For mills providing adequate records, all contaminated cider was produced from apples harvested between mid October and mid November.

  17. Patulin surveillance in apple cider and juice marketed in Michigan.

    PubMed

    Harris, Kerri L; Bobe, Gerd; Bourquin, Leslie D

    2009-06-01

    Patulin is the most common mycotoxin found in apples and apple juices. The objective of this study was to determine the concentrations of patulin in (i) apple cider produced and marketed by Michigan apple cider mills during the fall seasons of 2002 to 2003 and 2003 to 2004 and (ii) apple juice and cider, including shelf-stable products, marketed in retail grocery stores in Michigan throughout 2005 and 2006. End product samples (n=493) obtained from 104 Michigan apple cider mills were analyzed for patulin concentration by using solid-phase extraction followed by high-performance liquid chromatography. Patulin was detected (> or =4 microg/liter) in 18.7% of all cider mill samples, with 11 samples (2.2%) having patulin concentrations of > or =50 microg/liter. A greater percentage of cider samples obtained from mills using thermal pasteurization contained detectable patulin (28.4%) than did those from mills using UV light radiation (13.5%) or no pathogen reduction treatment (17.0%). Among retail grocery store samples (n=159), 23% of apple juice and cider samples contained detectable patulin, with 18 samples (11.3%) having patulin concentrations of > or =50 microg/liter. The U.S. Food and Drug Administration (FDA) action level for patulin is 50 microg/kg. Some apple juice samples obtained from retail grocery stores had exceptionally high patulin concentrations, ranging up to 2700 microg/liter. Collectively, these results indicate that most apple cider and juice test samples from Michigan were below the FDA action level for patulin but that certain apple cider and juice processors have inadequate controls over patulin concentrations in final products. The industry, overall, should focus on improved quality of fruit used in juice production and improve culling procedures to reduce patulin concentrations.

  18. Characteristics and performance of four new apple rootstock from the Cornell-USDA apple rootstock breeding program

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In 2010, the apple rootstock breeding program at Geneva, NY released 4 new apple rootstocks (Geneva® 210, Geneva® 214, Geneva® 890 and Geneva® 969). G.210 is a semi-dwarfing rootstock with vigor similar to M.7, with high productivity similar to M.9 and resistance to fire blight, phytophthora root ro...

  19. Dw2 a new dwarfing locus in apple rootstocks and relationship to induction of early bearing in apple scions

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The ability of certain apple rootstocks to dwarf their scions has been known for centuries and spurred a revolution in apple production. In this investigation, several breeding populations, in multiple replicated field and pot experiments were used to ascertain the degree of dwarfing of segregating...

  20. Obtaining Help with AppleWorks V2.0 Word Processing Files Using the Apple IIGS Computer. First Edition.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This guide was developed as a "how to" training device for obtaining help with AppleWorks version 2.0 word processing files using the Apple IIGS computer with two disk drives. Step-by-step instructions are provided for program loading; selecting the help list; and using the help list to copy text, delete text, find parts of a document,…

  1. Merging Spreadsheet and Word Processing Files Using AppleWorks V2.0 and the Apple IIGS Computer.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This guide was developed as a "how to" training device for merging spreadsheet and word processing files using AppleWorks version 2.0 and the Apple IIGS computer with two disk drives. Step-by-step instructions are provided for loading spreadsheet and word processor files, transferring spreadsheet files to the clipboard, merging…

  2. Using AppleWorks V2.0 To Construct Spreadsheet Files for the Apple IIGS Computer.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This guide was developed as a "how to" training device for constructing spreadsheet files using AppleWorks version 2.0 and the Apple IIGS computer with two disk drives. Step-by-step instructions are provided for program loading, selecting the spreadsheet option, setting column widths, naming columns and fields, entering category…

  3. Merging Data Base and Word Processing Files Using AppleWorks V2.0 and the Apple IIGS Computer.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This guide was developed as a "how to" training device for merging database and word processing files using AppleWorks version 2.0 and the Apple IIGS computer with two disk drives. Step-by-step instructions are provided for loading database files, transferring database files to the clipboard, merging database files into word processor…

  4. Converting Spreadsheet Files into Data Base Files Using AppleWorks V2.0 and the Apple IIGS Computer.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This guide was developed as a "how to" training device for converting spreadsheet files into database files using AppleWorks version 2.0 on the Apple IIGS computer with two disk drives. Step-by-step instructions are provided for loading spreadsheet files, transferring spreadsheet files to the monitor, printing spreadsheet files, and…

  5. Economic analysis of a self-propelled apple harvest and in-field sorting machine for the apple industry

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The U.S. apple industry, which generated more than $2.7 billion revenue at the farm gate in 2013, is facing critical challenges in decreased availability of labor and increased labor and production cost. To address these challenges, a self-propelled apple harvest and automated in-field sorting machi...

  6. 2015 Progress Report – Evaluation of the Cornell-Geneva Apple Rootstocks and Other Promising Apple Rootstocks

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A number of new apple rootstocks from the Cornell/USDA apple rootstock breeding project, located at Geneva, NY which are resistant to fire blight are rapidly becoming available to the industry. These rootstocks are also dwarfing, tolerant to replant disease and productive. Data on cumulative yield...

  7. Comment on "In situ imaging of ultra-fast loss of nanostructure in nanoparticle aggregates" [J. Appl. Phys. 115, 084903 (2014)

    NASA Astrophysics Data System (ADS)

    Levitas, Valery I.; Hwang, Yong Seok

    2016-02-01

    One of the conclusions of a recent article by Egan et al. [J. Appl. Phys. 115, 084903 (2014)] was that since the melt-dispersion mechanism (MDM) of the reaction of aluminum nanoparticles was not observed in their experiments, this mechanism is very unlikely. Our main point here is to demonstrate that, in fact, these experiments do not disprove the MDM.

  8. Genetic control of biennial bearing in apple

    PubMed Central

    Guitton, Baptiste; Kelner, Jean-Jacques; Velasco, Riccardo; Gardiner, Susan E.; Chagné, David; Costes, Evelyne

    2012-01-01

    Although flowering in mature fruit trees is recurrent, floral induction can be strongly inhibited by concurrent fruiting, leading to a pattern of irregular fruiting across consecutive years referred to as biennial bearing. The genetic determinants of biennial bearing in apple were investigated using the 114 flowering individuals from an F1 population of 122 genotypes, from a ‘Starkrimson’ (strong biennial bearer)בGranny Smith’ (regular bearer) cross. The number of inflorescences, and the number and the mass of harvested fruit were recorded over 6 years and used to calculate 26 variables and indices quantifying yield, precocity of production, and biennial bearing. Inflorescence traits exhibited the highest genotypic effect, and three quantitative trait loci (QTLs) on linkage group (LG) 4, LG8, and LG10 explained 50% of the phenotypic variability for biennial bearing. Apple orthologues of flowering and hormone-related genes were retrieved from the whole-genome assembly of ‘Golden Delicious’ and their position was compared with QTLs. Four main genomic regions that contain floral integrator genes, meristem identity genes, and gibberellin oxidase genes co-located with QTLs. The results indicated that flowering genes are less likely to be responsible for biennial bearing than hormone-related genes. New hypotheses for the control of biennial bearing emerged from QTL and candidate gene co-locations and suggest the involvement of different physiological processes such as the regulation of flowering genes by hormones. The correlation between tree architecture and biennial bearing is also discussed. PMID:21963613

  9. Comment on "Analysis of single-layer metamaterial absorber with reflection theory" [J. Appl. Phys. 117, 154906 (2015)

    NASA Astrophysics Data System (ADS)

    Tung, Nguyen Thanh

    2016-03-01

    In a recent paper, Xiong et al. [J. Appl. Phys. 117, 154906 (2015)] presented the simulated results of a Jerusalem-cross structure in an attempt to elaborate their proposed reflection theory for metamaterial absorbers. Noting that even at non-resonant frequencies the real part of the permeability shows an over-high average value and its imaginary part drops abruptly from positivity to negativity, we argue that their simulated results are unphysical, resulting from an incomplete understanding of the retrieval procedure.

  10. Re-evaluation of an Optimized Second Order Backward Difference (BDF2OPT) Scheme for Unsteady Flow Applications

    NASA Technical Reports Server (NTRS)

    Vatsa, Veer N.; Carpenter, Mark H.; Lockard, David P.

    2009-01-01

    Recent experience in the application of an optimized, second-order, backward-difference (BDF2OPT) temporal scheme is reported. The primary focus of the work is on obtaining accurate solutions of the unsteady Reynolds-averaged Navier-Stokes equations over long periods of time for aerodynamic problems of interest. The baseline flow solver under consideration uses a particular BDF2OPT temporal scheme with a dual-time-stepping algorithm for advancing the flow solutions in time. Numerical difficulties are encountered with this scheme when the flow code is run for a large number of time steps, a behavior not seen with the standard second-order, backward-difference, temporal scheme. Based on a stability analysis, slight modifications to the BDF2OPT scheme are suggested. The performance and accuracy of this modified scheme is assessed by comparing the computational results with other numerical schemes and experimental data.

  11. Kinetics of patulin degradation in model solution, apple cider and apple juice by ultraviolet radiation.

    PubMed

    Zhu, Yan; Koutchma, Tatiana; Warriner, Keith; Shao, Suqin; Zhou, Ting

    2013-08-01

    Patulin is a mycotoxin produced by a wide range of molds involved in fruit spoilage, most commonly by Penicillium expansum and is a health concern for both consumers and manufacturers. The current study evaluated feasibility of monochromatic ultraviolet (UV) radiation at 253.7 nm as a possible commercial application for the reduction of patulin in fresh apple cider and juice. The R-52G MINERALIGHT® UV bench top lamp was used for patulin destruction. It was shown that 56.5%, 87.5%, 94.8% and 98.6% reduction of patulin can be achieved, respectively, in the model solution, apple cider, apple juice without ascorbic acid addition and apple juice with ascorbic acid addition in 2-mm thickness sample initially spiked by 1 mg·L(-1) of patulin after UV exposure for 40 min at UV irradiance of 3.00 mW·cm(-2). A mathematic model to compare the degradation rate and effective UV dose was developed. The effective UV doses that were directly absorbed by patulin for photochemical reaction were 430, 674, 724 and 763 mJ·cm(-3), respectively. The fluence-based decimal reduction time was estimated to 309.3, 31.3, 28.9 and 5.1 mW·cm(-2)·min, respectively, in four media mentioned above. The degradation of patulin followed the first-order reaction model. The time-based and fluence-based reaction rate constants were determined to predict patulin degradation. The time-based reaction rate constant of samples treated in dynamic regime with constant stirring (model solution: 2.95E-4 s(-1), juice: 4.31E-4 s(-1)) were significantly higher than samples treated in static regime (model solution: 2.79E-4 s(-1), juice: 3.49E-4 s(-1), p < 0.05) when applied UV irradiance and sample thickness were consistent. The reaction rate constant of patulin degradation in apple juice was significantly higher than model solution (p < 0.05). Although further investigations are still needed, the results of this study demonstrated that UV radiation may be an effective method for

  12. Inactivation of Escherichia coli O157:H7 in apple juice and apple cider by trans-cinnamaldehyde.

    PubMed

    Baskaran, Sangeetha Ananda; Amalaradjou, Mary Anne Roshni; Hoagland, Thomas; Venkitanarayanan, Kumar

    2010-06-30

    This study investigated the antimicrobial effect of low concentrations of trans-cinnamaldehyde (TC) on Escherichia coli O157:H7 in apple juice and apple cider. A five-strain mixture of E. coli O157:H7 was inoculated into apple juice or cider at approximately 6.0 log CFU/ml, followed by the addition of TC (0%v/v, 0.025%v/v, 0.075%v/v and 0.125%v/v). The inoculated apple juice samples were incubated at 23 degrees C and 4 degrees C for 21 days, whereas the cider samples were stored only at 4 degrees C. The pH of apple juice and cider, and E. coli O157:H7 counts were determined on days 0, 1, 3, 5, 7, 14 and 21. TC was effective (P<0.05) in inactivating E. coli O157:H7 in apple juice and apple cider. At 23 degrees C, 0.125 and 0.075%v/v TC completely inactivated E. coli O157:H7 in apple juice (negative by enrichment) on days 1 and 3, respectively. At 4 degrees C, 0.125 and 0.075%v/v TC decreased the pathogen counts in the juice and cider to undetectable levels on days 3 and 5, respectively. Results indicate that low concentrations of TC could be used as an effective antimicrobial to inactivate E. coli O157:H7 in apple juice and apple cider.

  13. 7 CFR 319.56-27 - Apples from Japan and the Republic of Korea.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 5 2012-01-01 2012-01-01 false Apples from Japan and the Republic of Korea. 319.56-27... § 319.56-27 Apples from Japan and the Republic of Korea. Any variety of Malus domestica apples may be imported into the United States from Japan, and Fuji variety apples may be imported into the United...

  14. 7 CFR 319.56-27 - Apples from Japan and the Republic of Korea.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 5 2011-01-01 2011-01-01 false Apples from Japan and the Republic of Korea. 319.56-27... § 319.56-27 Apples from Japan and the Republic of Korea. Any variety of Malus domestica apples may be imported into the United States from Japan, and Fuji variety apples may be imported into the United...

  15. 7 CFR 319.56-27 - Apples from Japan and the Republic of Korea.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 5 2014-01-01 2014-01-01 false Apples from Japan and the Republic of Korea. 319.56-27... § 319.56-27 Apples from Japan and the Republic of Korea. Any variety of Malus domestica apples may be imported into the United States from Japan, and Fuji variety apples may be imported into the United...

  16. 7 CFR 319.56-27 - Apples from Japan and the Republic of Korea.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 5 2013-01-01 2013-01-01 false Apples from Japan and the Republic of Korea. 319.56-27... § 319.56-27 Apples from Japan and the Republic of Korea. Any variety of Malus domestica apples may be imported into the United States from Japan, and Fuji variety apples may be imported into the United...

  17. Use of cyclodextrin-based polymer for patulin analysis in apple juice

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Penicillium expansum, one of the patulin producing fungi that causes decay on apple, is recognized as the main source of patulin contamination on apple and apple products. The widely used method for patulin analysis in apple juice is liquid-liquid extraction with ethyl acetate followed by HPLC-UV or...

  18. Creating, Storing, and Dumping Low and High Resolution Graphics on the Apple IIe Microcomputer System.

    ERIC Educational Resources Information Center

    Fletcher, Richard K., Jr.

    This description of procedures for dumping high and low resolution graphics using the Apple IIe microcomputer system focuses on two special hardware configurations that are commonly used in schools--the Apple Dot Matrix Printer with the Apple Parallel Interface Card, and the Imagewriter Printer with the Apple Super Serial Interface Card. Special…

  19. Gene expression profiles for two auxin transporters during apple fruit maturation and ripening

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The maturation and ripening patterns of apple varieties differ greatly due to their long history of cultivation, self-incompatible nature and the high-level heterozygosity of the apple genome. The ripening season across elite apple cultivars can span more than three months. Apple maturation and ripe...

  20. QTL analysis of soft scald in two apple populations

    PubMed Central

    McClure, Kendra A; Gardner, Kyle M; Toivonen, Peter MA; Hampson, Cheryl R; Song, Jun; Forney, Charles F; DeLong, John; Rajcan, Istvan; Myles, Sean

    2016-01-01

    The apple (Malus×domestica Borkh.) is one of the world’s most widely grown and valuable fruit crops. With demand for apples year round, storability has emerged as an important consideration for apple breeding programs. Soft scald is a cold storage-related disorder that results in sunken, darkened tissue on the fruit surface. Apple breeders are keen to generate new cultivars that do not suffer from soft scald and can thus be marketed year round. Traditional breeding approaches are protracted and labor intensive, and therefore marker-assisted selection (MAS) is a valuable tool for breeders. To advance MAS for storage disorders in apple, we used genotyping-by-sequencing (GBS) to generate high-density genetic maps in two F1 apple populations, which were then used for quantitative trait locus (QTL) mapping of soft scald. In total, 900 million DNA sequence reads were generated, but after several data filtering steps, only 2% of reads were ultimately used to create two genetic maps that included 1918 and 2818 single-nucleotide polymorphisms. Two QTL associated with soft scald were identified in one of the bi-parental populations originating from parent 11W-12-11, an advanced breeding line. This study demonstrates the utility of next-generation DNA sequencing technologies for QTL mapping in F1 populations, and provides a basis for the advancement of MAS to improve storability of apples. PMID:27651916