Maritime Threat Detection Using Probabilistic Graphical Models
2012-01-01
CRF, unlike an HMM, can represent local features, and does not require feature concatenation. MLNs For MLNs, we used Alchemy ( Alchemy 2011), an...open source statistical relational learning and probabilistic inferencing package. Alchemy supports generative and discriminative weight learning, and...that Alchemy creates a new formula for every possible combination of the values for a1 and a2 that fit the type specified in their predicate
Method to Select Technical Terms for Glossaries in Support of Joint Task Force Operations
2012-01-01
have been prohibitively time-consuming. Instead, we identified two publicly available terminology extractor tools: TerMine (NaCTEM, 2011) and Alchemy ...and that from the latter, by high recall. The Alchemy approach contrasts with that used in TerMine in that Alchemy will process the text with...information categories, such as person, location, and organization, in addition to returning topic keywords. Output from both TerMine and Alchemy
Maritime Threat Detection using Plan Recognition
2012-11-01
logic with a probabilistic interpretation to represent expert domain knowledge [13]. We used Alchemy [14] to implement MLN-BR. It interfaces with the...Domingos, P., & Lowd, D. (2009). Markov logic: An interface layer for AI. Morgan & Claypool. [14] Alchemy (2011). Alchemy ─ Open source AI. [http
Translating Ancient Alchemy: Fragments of Graeco-Egyptian Alchemy in Arabic Compendia.
Martelli, Matteo
2017-11-01
Translation played a vital role in the development and transfer of alchemy in Antiquity and the Early Middle Ages. Since its origins in Graeco-Roman Egypt, alchemy was encapsulated in Greek texts which allegedly relied on Persian or Egyptian sources. Later, a variety of Greek and Byzantine writings were translated into Syriac and Arabic, and these translations were in turn fragmented and disseminated in later Arabic compendia. This paper will first review the main phases of this historical process of transmission of alchemy from one language and culture to another. Second, this process will be examined using two significant case studies: a close analysis of various quotations from Graeco-Egyptian authors (Pseudo-Democritus, Zosimus of Panopolis, and Synesius) as presented in two Arabic dialogues on alchemy, The Tome of Images and The Dialogue between Āras and the King Caesar. These sources demonstrate some of the concrete textual realities that underlie general patterns of translation and reception.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-01
... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0048] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ALCHEMY; Invitation for Public Comments AGENCY... ALCHEMY is: Intended Commercial Use of Vessel: ``Uninspected six-pack sailing charters and instruction...
Alchemy and the history of science. Introduction.
Moran, Bruce T
2011-06-01
Alchemy is part of the cultural experience of early modern Europe and yet has had to overcome problems of demarcation to be considered relevant to the history of science. This essay considers historiographical and methodological issues that have affected the gradual demarginalization of alchemy among attempts to explain, and find things out about, nature. As an area of historical study, alchemy relates to the history of science as part of an ensemble of practices that explored the natural world through natural philosophy and speculative traditions and by functioning as a nexus of social and intellectual life.
2013-10-01
Based Logistics Prophets Using Science or Alchemy to Create Life-Cycle Affordability? Using Theory to Predict the Efficacy of Performance Based...Using Science or Alchemy to Create Life-Cycle Affordability? Using Theory to Predict the Efficacy of Performance Based Logistics 5a. CONTRACT NUMBER 5b...Are the PBL Prophets Using Science or Alchemy to Create Life Cycle Affordability? 328Defense ARJ, October 2013, Vol. 20 No. 3 : 325–348 Defense
Stoicism and Alchemy in Late Antiquity: Zosimus and the Concept of Pneuma.
Rinotas, Athanasios
2017-08-01
At the beginning of the twentieth century, historians associated the alchemy of the third-century alchemist Zosimus of Panopolis with Platonism and Aristotelianism, explicating his theory of alchemical transmutation under the intellectual umbrella of these philosophical traditions. More recently, scholars of alchemy such as Christina Viano and William Newman have suggested a connection between Zosimean alchemy and Stoicism. Through a close reading of texts in Zosimus's corpus, this paper posits a Stoic interpretation of several aspects of Zosimean alchemy, focusing on the concepts of pneuma and tension. For Zosimus, I argue, pneuma played a vital role in colouring metals, while tension conferred stability and cohesion upon metallic compounds. This interpretation suggests that Zosimus applied Stoic concepts to describe the alchemical process of tincturing metals.
Educational Alchemy: The Transformation of Schools.
ERIC Educational Resources Information Center
Mugits, Michael James
Alchemy is the magical or mysterious power or process involving chemistry, magic, and philosophy in transforming one thing into another. The term is often used to describe the medieval study that sought to transform cheaper metals into gold or silver. "Educational alchemy" is the process by which schools are converted into more effective learning…
THE SINO-INDIAN ORIGIN OF CHEMEIA AND CHUMEIA AS SYNONYMS IN GREK, SIGNIFYING ALCHEMY
Mahdihassan, S.
1984-01-01
In China the antecedent of alchemy is represented by the god of longevity emerging from the peach. The first synthetic drug, Kim-Yeh, red colloidal gold, signified gold-cum -herbal juice. Kim-Yeh=Kimiya (Arabic) =chemeia (Greek). Translated this gave Chrusozomion=Gold Ferment, specifying the drug. Rasayana was translated as Chumeia, herbal juice-incorporate and signified the art alchemy. Chemeia was Chinese and Chumeia, Indian. Originally each signified both, a drug of longevity and the art, alchemy. Finally the art of making red gold was misunderstood as the art of making gold itself PMID:22557463
Words and works in the history of alchemy.
Nummedal, Tara E
2011-06-01
This essay considers the implications of a shift in focus from ideas to practices in the history of alchemy. On the one hand, it is argued, this new attention to practice highlights the diversity of ways that early modern Europeans engaged alchemy, ranging from the literary to the entrepreneurial and artisanal, as well as the broad range of social and cultural spaces that alchemists inhabited. At the same time, however, recent work has demonstrated what most alchemists shared-namely, a penchant for reading, writing, making, and doing, all at the same time. Any history of early modern alchemy, therefore, must attend to all of these practices, as well as the interplay among them. In this sense, alchemy offers a model for thinking and writing about early modern science more generally, particularly in light of recent work that has explored the intersection of scholarly, artisanal, and entrepreneurial forms of knowledge in the early modem period.
Improving the Accuracy and Scalability of Discriminative Learning Methods for Markov Logic Networks
2011-05-01
9 2.2 Inductive Logic Programming and Aleph . . . . . . . . . . . . 10 2.3 MLNs and Alchemy ...positive examples. Aleph allows users to customize each of 10 these steps, and thereby supports a variety of specific algorithms. 2.3 MLNs and Alchemy An...tural motifs. By limiting the search to each unique motif, LSM is able to find good clauses in an efficient manner. Alchemy (Kok, Singla, Richardson
Plan Recognition using Statistical Relational Models
2014-08-25
arguments. Section 4 describes several variants of MLNs for plan recognition. All MLN mod- els were implemented using Alchemy (Kok et al., 2010), an...For both MLN approaches, we used MC-SAT (Poon and Domingos, 2006) as implemented in the Alchemy system on both Monroe and Linux. Evaluation Metric We...Singla P, Poon H, Lowd D, Wang J, Nath A, Domingos P. The Alchemy System for Statistical Relational AI. Techni- cal Report; Department of Computer Science
"Decknamen or pseudochemical language"? Eirenaeus Philalethes and Carl Jung.
Newman, W R
1996-01-01
It is impossible to investigate the historiography of alchemy without encountering the ideas of the "father of analytical psychology", Carl Jung. Jung argued that alchemy, viewed as a diachronic, trans-cultural entity, was concerned more with psychological states occurring in the mind of the practitioner than with real chemical processes. In the course of elucidating this idea, Jung draws on a number of alchemical authors from the early modern period. One of these is Eirenaeus Philalethes, the pen name of George Starkey (1628-1665), a native of Bermuda who was educated at Harvard College, and who later immigrated to London. A careful analysis of Starkey's work shows, however, that Jung was entirely wrong in his assessment of this important representative of seventeenth-century alchemy. This finding casts serious doubt on the Jungian interpretation of alchemy as a whole.
Płonka-Syroka, B
2000-01-01
In his work, Psychologie und Alchemie, published in 1944, Jung wanted to present a reconstruction of alchemy. In order to do this he used a method of psychology, which he modified and enriched with inspirations drawn from neo-romantically-oriented German medical historiographies of the nineteen thirties. Using historical materials, he intended to demonstrate the empirical character of his Depth Psychology, a widespread concept, ingrained in our supra-personal social unconscious. The present article questions the nature of Jung's reconstruction of alchemy as historical reconstruction. The author presents the methodological bases referred to by Jung derived from his concept of medical practice and compares them with a manner of thinking typical of contemporary historical analysis. The article also presents Jung's inspirations from the medical historiography of his time, as well as the dissimilarity of his concept with the model of historical narrative construction in force in the historiography of the thirties and forties. At the same time, it presents the elements of the "romantic inheritance" in Jung's thought, drawn from the tradition of German non-materialistic medicine of the first half of the nineteenth century.
Transmutation: The Roots of the Dream.
ERIC Educational Resources Information Center
Karpenko, Vladimir
1995-01-01
Examines the history of alchemical attempts at transmutation and classifies them by differing approaches and techniques. Traces the development of alchemy in Asia, Europe, and the Middle East, and compares alchemy with craftsmanship. (18 references) (DDR)
Agosto-Arroyo, Emmanuel; Coshatt, Gina M; Winokur, Thomas S; Harada, Shuko; Park, Seung L
2017-01-01
The molecular diagnostics laboratory faces the challenge of improving test turnaround time (TAT). Low and consistent TATs are of great clinical and regulatory importance, especially for molecular virology tests. Laboratory information systems (LISs) contain all the data elements necessary to do accurate quality assurance (QA) reporting of TAT and other measures, but these reports are in most cases still performed manually: a time-consuming and error-prone task. The aim of this study was to develop a web-based real-time QA platform that would automate QA reporting in the molecular diagnostics laboratory at our institution, and minimize the time expended in preparing these reports. Using a standard Linux, Nginx, MariaDB, PHP stack virtual machine running atop a Dell Precision 5810, we designed and built a web-based QA platform, code-named Alchemy. Data files pulled periodically from the LIS in comma-separated value format were used to autogenerate QA reports for the human immunodeficiency virus (HIV) quantitation, hepatitis C virus (HCV) quantitation, and BK virus (BKV) quantitation. Alchemy allowed the user to select a specific timeframe to be analyzed and calculated key QA statistics in real-time, including the average TAT in days, tests falling outside the expected TAT ranges, and test result ranges. Before implementing Alchemy, reporting QA for the HIV, HCV, and BKV quantitation assays took 45-60 min of personnel time per test every month. With Alchemy, that time has decreased to 15 min total per month. Alchemy allowed the user to select specific periods of time and analyzed the TAT data in-depth without the need of extensive manual calculations. Alchemy has significantly decreased the time and the human error associated with QA report generation in our molecular diagnostics laboratory. Other tests will be added to this web-based platform in future updates. This effort shows the utility of informatician-supervised resident/fellow programming projects as learning opportunities and workflow improvements in the molecular laboratory.
Alchemy--A History of Early Technology.
ERIC Educational Resources Information Center
Pollard, A. M.
1988-01-01
Reviews the history of alchemy including personalities and methods. Discusses the philosophy associated with various early chemists and alchemists. Attempts to show that it was not unreasonable for ancient alchemists to believe in the possibility of transmutation. (CW)
Story Behind the Story: Some Latter-Day Alchemists.
ERIC Educational Resources Information Center
Wotiz, John H., Ed.; Trimble, R. F.
1980-01-01
This article is a brief survey of alchemy since the chemical revolution. It shows that the reasonable expectation that alchemy could not survive the new chemistry is wrong, through a description of the work and beliefs of several prominent alchemists. (Author/DS)
How the Alchemy Makes Inquiry, Evidence, and Exclusion.
ERIC Educational Resources Information Center
Popkewitz, Thomas S.
2002-01-01
Modern teaching and teacher education "magically" transform sciences, social sciences, and humanities. The alchemy of school subjects provides a way to think about frames of reference organizing inquiry and constitutes evidence in teacher education, also obscuring the normalizing and dividing practices of teaching (including…
Alchemy and mining: metallogenesis and prospecting in early mining books.
Dym, Warren Alexander
2008-11-01
Historians have assumed that alchemy had a close association with mining, but exactly how and why miners were interested in alchemy remains unclear. This paper argues that alchemical theory began to be synthesised with classical and Christian theories of the earth in mining books after 1500, and served an important practical function. The theory of metals that mining officials addressed spoke of mineral vapours (Witterungen) that left visible markings on the earth's surface. The prospector searched for mineral ore in part by studying these indications. Mineral vapours also explained the functioning of the dowsing rod, which prospectors applied to the discovery of ore. Historians of early chemistry and mining have claimed that mining had a modernising influence by stripping alchemy of its theoretical component, but this paper shows something quite to the contrary: mining officials may have been sceptical of the possibility of artificial transmutation, but they were interested in a theory of the earth that could translate into prospecting knowledge.
Agosto-Arroyo, Emmanuel; Coshatt, Gina M.; Winokur, Thomas S.; Harada, Shuko; Park, Seung L.
2017-01-01
Background: The molecular diagnostics laboratory faces the challenge of improving test turnaround time (TAT). Low and consistent TATs are of great clinical and regulatory importance, especially for molecular virology tests. Laboratory information systems (LISs) contain all the data elements necessary to do accurate quality assurance (QA) reporting of TAT and other measures, but these reports are in most cases still performed manually: a time-consuming and error-prone task. The aim of this study was to develop a web-based real-time QA platform that would automate QA reporting in the molecular diagnostics laboratory at our institution, and minimize the time expended in preparing these reports. Methods: Using a standard Linux, Nginx, MariaDB, PHP stack virtual machine running atop a Dell Precision 5810, we designed and built a web-based QA platform, code-named Alchemy. Data files pulled periodically from the LIS in comma-separated value format were used to autogenerate QA reports for the human immunodeficiency virus (HIV) quantitation, hepatitis C virus (HCV) quantitation, and BK virus (BKV) quantitation. Alchemy allowed the user to select a specific timeframe to be analyzed and calculated key QA statistics in real-time, including the average TAT in days, tests falling outside the expected TAT ranges, and test result ranges. Results: Before implementing Alchemy, reporting QA for the HIV, HCV, and BKV quantitation assays took 45–60 min of personnel time per test every month. With Alchemy, that time has decreased to 15 min total per month. Alchemy allowed the user to select specific periods of time and analyzed the TAT data in-depth without the need of extensive manual calculations. Conclusions: Alchemy has significantly decreased the time and the human error associated with QA report generation in our molecular diagnostics laboratory. Other tests will be added to this web-based platform in future updates. This effort shows the utility of informatician-supervised resident/fellow programming projects as learning opportunities and workflow improvements in the molecular laboratory. PMID:28480121
Linked Data for Software Security Concepts and Vulnerability Descriptions
2013-07-01
named entity (NE) extractors such as DBpedia Spotlight, Alchemy API1, Extractiv2, OpenCalais3 and Zemanta were compared for their overall performance...presents substantial agreement for URI dis- ambiguation. Alchemy API, although preserving good performance in NE extraction and 1http://www.alchemyapi.com
The Alchemist and Early Chemist
ERIC Educational Resources Information Center
Husk, G. Ronald
1972-01-01
Alchemy can be used to establish that chemistry was also an art which later changed to science. Courses in alchemy will not only create more interest in science majors but non-science majors as well. The paintings identified in the article can be procured from commercial firms, and discussion lessons planned. (PS)
MARCELIN BERTHELOT AND INDIAN ALCHEMY
Rosu, Arion
1986-01-01
Based on unpublished manuscripts, the article reveals the keen interest shown by Marcelin Berthelot in Indian alchemy. The French Savant has actually inspired and encouraged the first historical research in this field, undertaken at the end of the last century, in Calcutta, by the Bengali scientist Prafulla Chandra Ray. PMID:22557533
Rhetoric, Alchemy and Heuristic Procedures: Some Epistemological Questions.
ERIC Educational Resources Information Center
Edwards, Bruce L., Jr.
Although composition theorists have rejected the "alchemy" of the traditional, impressionistic, unscientific view of composition as product in favor of a process oriented approach, they have as yet failed to reach a consensus about the epistemological bases that undergird this shift. An examination of parallel developments in literary…
The Aspiring Adept: Robert Boyle and His Alchemical Quest (Lawrence M. Principe)
NASA Astrophysics Data System (ADS)
Kovac, Jeffrey
1999-10-01
Robert Boyle is widely regarded as the Father of Modern Chemistry, who broke once and for all from the irrational, misguided alchemy that preceded him. One of the goals of this carefully researched and argued new book by Lawrence M. Principe, Assistant Professor in the Department of Chemistry and the Institute for the History of Science, Medicine, and Technology at The Johns Hopkins University, is to refute the two errors in this characterization of Boyle and to understand his life, thought, and work in the intellectual and social context of his time. This book is not for the casual reader; it is a detailed scholarly treatise in the history of science, but it provides a fresh and interesting perspective on Boyle and on the development of chemistry in the 17th century. Boyle is usually characterized as a modern scientist and his most famous book, The Skeptical Chymist, as a critique of traditional alchemy. Principe demonstrates that this characterization is based on a selective and sometimes incorrect reading of Boyle's works. Like Newton, Boyle was deeply involved in traditional transmutational alchemy, reading the works of other alchemists, performing experiments, and even witnessing transmutations. Alchemy, however, was not a monolith and Boyle adhered to what Principe tentatively identifies as a uniquely English school of supernatural alchemy. According to Principe, The Skeptical Chymist was mainly a criticism of the Paracelsians interested in chemical medicine rather than a defense of what we would now regard as modern chemistry. To further support his characterization of Boyle and to better reveal Boyle's involvement in alchemyparticularly the transmutation of base metals to gold, termed chrysopoeiaPrincipe has reconstructed from some 20 fragments one of Boyle's alchemical manuscripts, his Dialogue on the Transmutation of Metals. The full text of this lost work is included as Appendix 1. Two other primary sources, Interview Accounts of Transmutations and Prefaces to Boyle's Other Chrysopoetic Writings, and Robert Boyle's Dialogue on the Converse with Angels Aided by the Philosophers Stone, are also printed, as Appendices 2 and 3. Both Robert Boyle and 17th-century chemistry emerge from this book as exceedingly complex. The development of chemistry cannot be regarded as either straightforward or linear. As Boyle's work exemplifies, ideas from traditional alchemy were important in the development of chemistry. For example, Boyle's corpuscularian hypothesis is partly derived from the alchemical corpuscularian traditionthe minima of Geber. Alchemy was part of the intellectual context in which both Boyle and Newton were raised and it played an important part in their thinking. For Boyle, alchemy was also closely linked to Christianity. He regarded the philosophers' stone as a powerful weapon against the growing atheism of his time. The possessor of the stone could summon angels and other spirits, thus providing support for crucial theological truths. Religion was as important a motivation as both natural philosophy and the potential for the development of potent medicines for Boyle's study of alchemy. This book is a rich source of information on Robert Boyle, alchemy, and the development of 17th century chemistry. It is not an easy book, however; it requires close attention and some background in the history of science. For those interested in the development of modern science, this is a valuable addition to the growing collection of excellent new books.
[Magician nature and human magician: on a fundamental analogy of alchemy].
Schott, Heinz
2010-01-01
This contribution discusses Paracelsism-influenced early-modern alchemy. There are notably two forms of analogy, each hierarchically arranged: a vertically ordered analogy ("as above, thus below") in which Nature is situated as mediator between God and man, and a horizontally ordered analogy ("as without, thus within") in which Nature's magic is regarded as a model for man, particularly expressed in the metaphor of "Vulcan" (smith) and doctor (e.g., Nature as inner healer). In alchemy the conventional "healing power of Nature" is pin-pointed: The doctor (as alchemist, magician) must unravel Nature's secrets and emulate her magic to perfect her work -particularly medicine production. Diagrams and historical depictions illustrate this.
Communicating about Matter with Symbols: Evolving from Alchemy to Chemistry
ERIC Educational Resources Information Center
Fabbrizzi, Luigi
2008-01-01
Modern chemists know that alchemists were their historical predecessors, yet they are not proud of this relationship, which chemists today tend to hide or forget. However, no discontinuity exists between alchemy and chemistry and we still use laboratory techniques that were invented by alchemists hundreds or thousands of years ago. Alchemists used…
The Alchemy of the Mathematics Curriculum: Inscriptions and the Fabrication of the Child
ERIC Educational Resources Information Center
Popkewitz, Thomas
2004-01-01
School subjects are analogous to medieval alchemy. There is a magical change as mathematics, science, and social sciences move from their disciplinary spaces into the classroom. The educational and social psychologies have little or nothing to do with understanding disciplinary practices. They are intellectual inventions for normalizing and…
The Limits of Teacher Education Reforms: School Subjects, Alchemies, and an Alternative Possibility
ERIC Educational Resources Information Center
Popkewitz, Thomas
2010-01-01
Contemporary U.S. schools and professional reforms call for teachers to have greater disciplinary and pedagogical knowledge for teaching school subjects. Reform efforts leave unexamined the rules and standards of "reason" that historically order school subjects. The notion of alchemy provides an analytic "tool" to consider the…
2010-10-21
paper assess the reversible works needed to alchemi - cally change each molecule to the benzene core reference state. To automate the alchemical...the alchemi - cal free energies or reversible works, the TI procedure split the interval from the real state of the molecule at λ ) 0 to the reference
ERIC Educational Resources Information Center
Erduran, Sibel
Themes from history and philosophy of chemistry have traditionally been absent in chemistry education. This paper targets the problem of demarcationism within the context of chemistry and alchemy. In so doing, it argues that demarcationism can be an appropriate base for bringing the historical and philosophical aspects of the discipline of…
ERIC Educational Resources Information Center
Duncombe, William
2006-01-01
Reforming school finance systems to support performance standards entails estimating the cost of an adequate education. Cost of adequacy (COA) studies have been done in more than 30 states. Recently Eric Hanushek challenged the legitimacy of COA research, calling it alchemy and pseudoscience. The objectives of this study are to present reliability…
The Ars alchemie: the first Latin text on practical alchemy.
Vinciguerra, Antony
2009-03-01
The Ars alchemie is a collection of alchemical recipes associated with the names of the Arabic-Latin translator Michael Scot and the major general of the Friars Minor, Elias Cortona, of the first half of the thirteenth century. This articles investigates the various forms in which this text appears in the four manuscripts that contain it. It shows the dependence of one of its prologues on the work of an earlier translator, Hugo of Santalla, and the overlap of its contents with other alchemical treatises: Liber luminis luminum, Liber Dedali, Liber de aluminibus et salibus and Liber Hermetis de blchkmkb. Its mention of the alum of Aleppo corresponds with references to trade in this material in the thirteenth century. Its main characteristics are its compilatory nature and its emphasis on practical applications.
Alchemy and Aberrant Behaviour: A Jungian Approach to Working with Boys with Behaviour Disorders
ERIC Educational Resources Information Center
O'Dea, Robert
2006-01-01
Alchemy is an ancient philosophy on which the two modern day sciences of chemistry and analytical psychology are grounded. In education in New South Wales (NSW) at the present time, the behaviour of boys is of increasing concern to schools, to teachers, to parents and to society at large as evidenced by the over-representation of boys in school…
Leitão, José Vieira
2016-11-01
The Benedictine monk Benito Jerónimo Feijoo (1676-1764) is now considered one of the major figures of the Spanish and Iberian Enlightenment. However his work, both in Spain and in Portugal, was far from being universally acclaimed. His critical approach to the subject of alchemy in his essay "Piedra Filosofal," published in the third volume of his magisterial Teatro Crítico Universal (1726-1739), sparked an unexpected response from the Portuguese alchemist Anselmo Castelo Branco, who sought to refute Feijoo's claims in his own work, the Ennoea. This paper presents an outline of this exchange and its position within Iberian Enlightenment circles. It further argues that Castelo Branco's defence of alchemy was informed by his political and prophetic views, in particular his adherence to the Portuguese messianic doctrine of Sebastianism.
MANTRA AND YANTRA IN INDIAN MEDICINE AND ALCHEMY
Rosu, Arion
1988-01-01
This paper was presented at the International Workshop on mantras and ritual diagrams in Hinduism, held in Paris, 21-22 June1984. The complete text in French, which appeared in the Journal asiatique 1986, p.203, is based upon an analysis of Ayurvedc literature from ancient times down to the present and of numerous Sanskrit sources concerning he specialized sciences: alchemy and latrochemisry, veterinary medicine as well as agricultural and horticulture techniques. PMID:22557624
EnergyPlus Graphical User Interface
DOE Office of Scientific and Technical Information (OSTI.GOV)
2011-01-04
LBNL, Infosys Technologies and Digital Alchemy are developing a free, comprehensive graphical user interface (GUI) that will enable EnergyPlus to be used more easily and effectively by building designers and other professionals, facilitating its widespread adoption. User requirements have been defined through a series of practitioner workshops. A new schematic editor for HVAC systems will be combined with different building envelope geometry generation tools and IFC-based BIM import and export. LBNL and Digital Alchemy have generated a detailed function requirements specification, which is being implemented in software by Infosys, LBNL and and Digital Alchemy. LBNL and practitioner subcontractors will developmore » a comprehensive set of templates and libraries and will perform extensive testing of the GUI before it is released in Q3 2011. It is planned to use an Open Platfom approach, in which a comprehensive set of well documented Application Programming Interfaces (API's) would be provided to facilitate both the development of third party contributions to the official, standard GUI and the development of derivative works.« less
[Carl Gustav Jung's alchemical thinking].
Mirkiewicz, Jakub
2004-01-01
Carl Gustav Jung (1875-1961), Swiss psychologist and philosopher of culture used in his concepts many constructs having their source in philosophy of alchemy. These ideas can be found not only in his books on alchemy but also in his psychological works. Among them we should enumerate: the theory of psychological process, the concepts of opposites coexisting in the psyche, the polar structure of notions in his psychological system and the idea of synchronicity. The author of this article examines these main points of Jungian program within the context of its parallelism with paracelsian alchemical philosophy of nature: the process of nature, alchemical dialectics and the universal analogy of micro- and macrocosmos. At the beginning of his work, creating his psychology Jung assumed similar ideas. Later, when he noticed this similarity, alchemy became very helpful in his research of psyche, because thanks to them he conceptualised the successive aspects of polar structure of dynamical psychical reality, which--like his alchemical predecessors--he used to explain basics of the micro- and macro-world.
What have we learned from the recent historiography of alchemy?
Newman, William R
2011-06-01
Over the last two decades a new scholarship on alchemy has emerged, leading to a fundamental reformulation of knowledge about alchemists and their activities. We now know that medieval and early modern alchemists employed experiment in concert with theory to demonstrate the existence of stable "chymical atoms," which were thought to combine with one another according to a hierarchical theory of matter. Employing laboratory-based analysis and synthesis, alchemists were among the first explicitly to enunciate the principle of mass balance and to show that materials are compounded of the ingredients into which they can be physically decomposed. Perhaps even more surprisingly, these convictions and practices arose out of the interaction of alchemical practice with scholastic Aristotelianism, long viewed by historians of the Scientific Revolution as antithetical to experiment. Thus the new historiography challenges both a long-standing marginalization of alchemy itself and a commonplace view of Aristotelianism as inimical to the early modern growth of experimental science.
Wright, Mark H.; Tung, Chih-Wei; Zhao, Keyan; Reynolds, Andy; McCouch, Susan R.; Bustamante, Carlos D.
2010-01-01
Motivation: The development of new high-throughput genotyping products requires a significant investment in testing and training samples to evaluate and optimize the product before it can be used reliably on new samples. One reason for this is current methods for automated calling of genotypes are based on clustering approaches which require a large number of samples to be analyzed simultaneously, or an extensive training dataset to seed clusters. In systems where inbred samples are of primary interest, current clustering approaches perform poorly due to the inability to clearly identify a heterozygote cluster. Results: As part of the development of two custom single nucleotide polymorphism genotyping products for Oryza sativa (domestic rice), we have developed a new genotype calling algorithm called ‘ALCHEMY’ based on statistical modeling of the raw intensity data rather than modelless clustering. A novel feature of the model is the ability to estimate and incorporate inbreeding information on a per sample basis allowing accurate genotyping of both inbred and heterozygous samples even when analyzed simultaneously. Since clustering is not used explicitly, ALCHEMY performs well on small sample sizes with accuracy exceeding 99% with as few as 18 samples. Availability: ALCHEMY is available for both commercial and academic use free of charge and distributed under the GNU General Public License at http://alchemy.sourceforge.net/ Contact: mhw6@cornell.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:20926420
Critical Review of Rasaratna Samuccaya: A Comprehensive Treatise of Indian Alchemy
Sumersingh Rajput, Dhirajsingh; Gokarn, Rohit; Jagtap, Chandrashekhar Y; Galib, R; Patgiri, BJ; Prajapati, PK
2016-01-01
Rasaratna Samuccaya (RRS) a 13th century C.E. alchemical treatise, authored by Vāgbhaṭa, is a useful compilation related to preparation and properties of drugs of mineral and metallic origin. This text throws light on the state of Indian expertise in the field of alchemy regarding the extraction, purification, conversion of metals/minerals into therapeutically suitable forms, various instruments developed for alchemical purposes and treatment of numerous diseases by using herbo-mineral preparations. The present work is an attempt to summarize the key features of RRS to highlight its utility and contribution in the development of Indian alchemy. To study and summarize the important, comprehensive and specific points mentioned in RRS and to elaborate the contribution of RRS in the field of Indian alchemy. A critical review of RRS from Suratnojjvalā Hindi commentary by Ambikadatta Shastri was done and the collected information was compared with other available literature of Rasaśāstra. Research of modern science was also utilized to explore some facts mentioned by Vāgbhaṭa. RRS is a precise treatise among available ancient literature. It comprises of all eight branches of Ayurveda, although it mainly deals with therapeutic aspects of Rasaśāstra and emphasizes the use of metals and minerals in treating nearly 68 types of ailments. It contains 30 chapters, 3871 verses and detailed description of 960 formulations. Classification of metals and minerals; description of some new instruments, formulations and averting use of metals and minerals in pregnancy are the key features of RRS. PMID:28182027
Daniel David Palmer: alchemy in the creation of chiropractic.
Gaucher-Peslherbe, P L
1995-12-01
D.D. Palmer has been a much ignored man in the discipline he founded. The same applies to several early concepts he used to develop from a mere healer's background: D.D. Palmer invested them with an entirely different meaning. When considered, they help to understand the inner logic that allowed for chiropractic survival. There was an alchemy in the creation of chiropractic and the senior Palmer was the alchemist. He has not been recognized even within his own profession for the self-taught scholar and clinician that he was, knowledgeable about the various medical and scientific theories of his time.
BASIC CONCEPTS TO BE RECKONED IN A PROPER HISTORY OF ALCHEMY
Mahdihassan, S.
1986-01-01
Use of simple synthetic drug called Chin – Yeh, Gold – plus – plant juice or red colloidal gold. Gold made body everlasting and the herbal principle, as soul, increased life-span. Dialectally it was called Kim – Iya. Arabicized as Al – Kimiya it finally appeared as Alchemy. Chin – Yeh as drug was only brick – red when mercury, and sulphur – with traces of gold were sublimated there resulted Chin – Tan, Gold – plus – cinnabar. It was blood – red and with redness as soul it became the ideal drug of longevity. PMID:22557523
Alchemy, Chinese versus Greek, an etymological approach: a rejoinder.
Mahdihassan, S
1988-01-01
The theory generally accepted maintains that Alchemy arose at Alexandria as a child of Greek culture. It has two names, Chemeia as the earlier and Chumeia as the later. There is another theory that Alchemy arose in China. Its founder was the aged ascetic who longed after drugs of longevity. He first tried jade, next gold and cinnabar, but the ideal was a drug which was red like cinnabar and fire-proof like gold. But what was actually prepared was red colloidal gold or "calcined gold," by grinding gold granules in a decoction of an herb of longevity. It was called Chin-I; Chin = gold and I = plant juice. In Fukin dialect Chin-I = Kim-Iya. This was Arabicized, by pre-Islamic Arabs trading in silk with China, as Kimiya, whence arose Al-Kimiya and finally Al-chemy. It was first accepted by Bucharic speaking Copts in Egypt who transliterated Kimiya = Chemeia, pronouncing it as the Arabs did. With the increase of trade in silk the Chinese also went to Alexandria and helped the Greeks to translate Chin-I as Chrusozomion meaning, gold (making) ferment, instead of gold making plant juice. Consistent with this origin of the word Chemeia is the fact that the earlier Alchemists were not Greeks but probably Bucharic speaks Copts or Egyptians. The consumer of Chin-I or Chemeia became "a drug-made immortal" called Chin-Jen, Golden-Man. This was translated into Greek as Chrusanthropos. Thus the etymoloogy of two Greek words Chrusozomion and Chrusanthropos support the origin of the loan word, Chemeia as Chinese. To save space it is not proposed to discuss the origin of Chumeia.
Efficient Parameter Searches for Colloidal Materials Design with Digital Alchemy
NASA Astrophysics Data System (ADS)
Dodd, Paul, M.; Geng, Yina; van Anders, Greg; Glotzer, Sharon C.
Optimal colloidal materials design is challenging, even for high-throughput or genomic approaches, because the design space provided by modern colloid synthesis techniques can easily have dozens of dimensions. In this talk we present the methodology of an inverse approach we term ''digital alchemy'' to perform rapid searches of design-paramenter spaces with up to 188 dimensions that yield thermodynamically optimal colloid parameters for target crystal structures with up to 20 particles in a unit cell. The method relies only on fundamental principles of statistical mechanics and Metropolis Monte Carlo techniques, and yields particle attribute tolerances via analogues of familiar stress-strain relationships.
NASA Astrophysics Data System (ADS)
Jiang, F. D.; Feng, J. Y.
2008-02-01
Using first principles calculation, we systematically investigate the electronic modification of Cu-based chalcopyrite semiconductors induced by lattice deformation and composition alchemy. It is shown that the optical band gap Eg is remarkably sensitive to the anion displacement μ, resulting from the opposite shifts of conduction band minimum and valence band maximum. Meanwhile, the dependence of structural parameters of alloyed compounds on alloy composition x is demonstrated for both cation and anion alloying. The d orbitals of group-III cations are found to be of great importance in the calculation. Abnormal changes in the optical band gap Eg induced by anion alloying are addressed.
NASA Astrophysics Data System (ADS)
Sandhage, Kenneth H.
2010-06-01
The scalable fabrication of nano-structured materials with complex morphologies and tailorable chemistries remains a significant challenge. One strategy for such synthesis consists of the generation of a solid structure with a desired morphology (a “preform”), followed by reactive conversion of the preform into a new chemistry. Several gas/solid and liquid/solid reaction processes that are capable of such chemical conversion into new micro-to-nano-structured materials, while preserving the macroscopic-to-microscopic preform morphologies, are described in this overview. Such shape-preserving chemical transformation of one material into another could be considered a modern type of materials “alchemy.”
The way of sex: Joseph Needham and Jolan Chang.
Rocha, Leon Antonio
2012-09-01
This paper analyses the understandings of Daoist alchemy and Chinese sexuality of Joseph Needham and his friend and correspondent, the Chinese-Swedish writer Jolan Chang (Chang Chung-lan, 1917-2002). Using the extensive correspondence between the two men, as well as Needham's files on "inner alchemy" deposited at the Needham Research Institute, the paper begins with a partial reconstruction of a 1977 symposium, chaired by Needham, to promote Chang's new book, The Tao of Love and Sex: The Ancient Chinese Way to Ecstasy. Needham and Chang's visions of Chinese sex are then read against excerpts from Science and Civilisation in China, specifically Volume V: Chemistry and Chemical Technology, Part 5: Spagyrical Discovery and Invention: Physiological Alchemy (1983). Three inter-related aspects are explored. First, reading Science and Civilisation in China against materials in the Needham archives offers crucial hints to Needham's historiography and historical practice. Second, the way that Daoist regimens came to be actively reconstructed and repackaged as practices concerned with the enhancement of sexual pleasure and intensity. Third, the investigation of the networks and circulations of assumptions, visions, fantasies about "China". Copyright © 2012 Elsevier Ltd. All rights reserved.
Alchemy in popular culture: Leonardo Fioravanti and the search for the philosopher's stone.
Eamon, W
2000-05-01
This article examines the alchemical ideas and practices of the sixteenth-century Italian surgeon Leonardo Fioravanti. I argue that Fioravanti's "search for the philosopher's stone" was as much an effort at self-fashioning as a search for alchemical gold. Exploiting the fashion for alchemical drugs, he framed a "new theory" of healing that relied on the use of distilled drugs as a means of purging bodily corruptions. His theory resonated with popular culture, and made him the focus of an alternative medical movement. I conclude that Fioravanti's alchemy was not Paracelsianism, but relied much more on more immediate sources such as Arnald of Villanova, the pseudo-Lull, and the contemporary Milanese alchemist Ettore Ausonio.
THE SYMBOLS OF CREATIVE ENERGY IN THE LITERATURE ON MYSTICSM AND ON ALCHEMY
Mahdihassan, S.
1989-01-01
Alchemy as art tries to imitate creation such as spontaneous generation. The magic wands of creation, of Chinese origin, would be a compass and a triangular carpenter's square. Creation is represented by the dual-natured soul, comprising of the spirit (Ruh) and “the” soul (Nafs). The ultimate source is creative energy which emanates form the Divine word of command. Creative energy, in its non-manifest form, would be ultrasonic energy, which can be represented by a humming sourd. This would be sympolized by the humming sound. This would be symbolized by the humming sound of bees represent creative energy and in fig 3 the fiddle, as direct producers of a humming sound. PMID:22557649
California's "Free" Universities
ERIC Educational Resources Information Center
Cudhea, David
1974-01-01
Heliotrope, Orpheus, and Communiversity, San Francisco's three free universities, offer curricula with combinations of alchemy, magic, Volkswagen repairs, options in education, dance, conversational Mandarin, basic plumbing, and brain wave experiences. (Author/PG)
ERIC Educational Resources Information Center
Kolln, Martha
1981-01-01
Finds serious flaws in the research asserting the uselessness of teaching grammar to composition classes. Proposes that writing teachers acknowledge the presence and importance of grammar in the writing class. (RL)
Alchemy in eden: entrepreneurialism, branding, and food marketing in the United States, 1880–1920.
Lonier, Terri
2010-01-01
Through an investigation into the origins of American food marketing, this dissertation reveals how branding—specifically, the centennial brands Quaker Oats, Coca-Cola, and Crisco—came to underpin much of today's market-driven economy. In a manner akin to alchemy, the entrepreneurs behind these three firms recognized the inherent value of an agricultural Eden, then found ways to convert common, low-cost agricultural goods—oats, sugar, and cottonseed oil—into appealing, high-revenue branded food products. In the process, these ventures devised new demand-driven business models that exploited technology and communications advances, enabling them to tap a nascent consumer culture. Their pioneering efforts generated unprecedented profits, laid the foundation for iconic billion-dollar brands, and fundamentally changed how Americans make daily food choices.
Induced pluripotent stem cells--alchemist's tale or clinical reality?
Rashid, S Tamir; Vallier, Ludovic
2010-08-13
Following Shinya Yamanaka's first report describing the reprogramming of fibroblasts into stem cells over three years ago, some sceptics initially drew analogies between this new field of research and the quasi-mystical practice of 'alchemy'. Unlike the alchemist, however, stem cell researchers have rigorously tested and repeated experiments, proving their very own brand of cellular 'alchemy' to be a reality, with potentially massive implications for the study of human biology and clinical medicine. These investigations have resulted in an explosion of related publications and initiated the field of stem cell research known as 'induced pluripotency'. In this review, we give an account of the historical development, current technologies and potential clinical applications of induced pluripotency and conclude with a perspective on the possible future directions for this dynamic field.
Transmutation of Matter in Byzantium: The Case of Michael Psellos, the Alchemist
NASA Astrophysics Data System (ADS)
Katsiampoura, Gianna
2008-06-01
There is thus nothing paradoxical about the inclusion of alchemy in the ensemble of the physical sciences nor in the preoccupation with it on the part of learned men engaged in scientific study. In the context of the Medieval model, where discourse on the physical world was ambiguous, often unclear, and lacking the support of experimental verification, the transmutation of matter, which was the subject of alchemy, even if not attended by a host of occult features, was a process that was thought to have a probable basis in reality. What is interesting in this connection is the utilization of the scientific categories of the day for discussion of transmutation of matter and the attempt to avoid, in most instances in the texts that survive, of methods reminiscent of magic.
Principe, Lawrence M
2014-01-01
The general abandonment of serious endeavor toward metallic transmutation represents a major development in the history of chemistry, yet its exact causes and timing remain unclear. This essay examines the fate of chrysopoeia at the eighteenth-century Académie Royale des Sciences. It reveals a long-standing tension between Académie chemists, who pursued transmutation, and administrators, who tried to suppress it. This tension provides background for Etienne-François Geoffroy's 1722 paper describing fraudulent practices around transmutation. Although transmutation seems to disappear after Geoffroy's paper, manuscripts reveal that most of the institution's chemists continued to pursue it privately until at least the 1760s, long after widely accepted dates for the "demise of alchemy" in learned circles.
Alchemy of the Oracle: The Delphi Technique.
ERIC Educational Resources Information Center
Wilhelm, William J.
2001-01-01
Discusses the origins and foundations of the Delphi technique. Outlines procedures for using it in research to obtain the insights of experts. Addresses limitations of the technique. (Contains 44 references.) (SK)
Light-seeds within: The alchemy of re-finding light in the world soul
NASA Astrophysics Data System (ADS)
Erickson, Stacy Lynn
The light of the Anima Mundi has been repressed for over two thousand years. From a feminine in-sighting, this dissertation considers the reasons for the World Soul's repression and how her light can be renewed. The division of body and mind, image and word, physicality and spirituality, as well as nature and science has been costly, though this time of crisis also holds great opportunity to change perspective and live differently. The art of alchemy contains the secrets to transform elements in opposition into those in relationship in order to give birth to something new. Where feminine and masculine have been divorced and divided, the 'Royal Art' of alchemy seeks to renew soul in the world as an experience of life's interconnectivity and as a sacred marriage of matter and spirit. Through the four elements and three alchemical stages, this journey articulates the amorphous unconscious to evolve the light within the body of the microcosm and the macrocosm. The study's phenomenological perspective merges creative imagination with experiential gnosis in an exploration of the rich tapestry and mystery of an esoteric tradition. Through dream tending and active imagination, one connects to the subtle body, the imaginal world, and mythological regions with archetypal energies where elemental symbols are seeds. When cultivated and tended, these seeds grow into embodied feelings, visceral happenings. These experiential moments contain the revelations necessary for personal and global transmutation. Alchemy's tenet of 'as above, so below' holds a simple truth. When an individual works on her light, the Anima Mundi's light grows brighter. The alchemical process awakens love as the animating essence, the divine spark within the heart of all life---the gold in every atom of creation. Where matter and spirit conjoin, the hierosgamos reveals life's divine nature as an intimate dance and a web of interconnectivity. When lived for the sake of the whole and seen with the eyes of an awakened heart, life becomes an experience beyond the constrictions of preconceived ideas. Existence opens to the magic of the numinous world alive.
Alchemy and Exorcism in American Educational Thought.
ERIC Educational Resources Information Center
Gumbert, Edgar B.
1982-01-01
The author presents a critique of twentieth-century behaviorism and humanism as educational theories. He argues that the techniques of both lead to unwarranted intervention in individual lives and ceaseless human engineering. (SK)
A Conversation with the New Alchemists.
ERIC Educational Resources Information Center
Greene, Wade
1978-01-01
Reports on a visit to the New Alchemy Institute, a cluster of windmills and fish and vegetable production systems on a 12-acre site on Cape Cod. They are active in the appropriate technology movement. (BB)
ERIC Educational Resources Information Center
Seymour, Raymond B.
1988-01-01
Describes the history of the human understanding of polymers from alchemy to modern times. Discusses renaissance chemistry, polymers in the nineteenth century, synthetic elastomers, thermoplastic elastomers, fibers, coatings, adhesives, derivatives of natural rubber, thermosets, step-reaction, and chain polymerization. (CW)
Viridarium Chymicum: The Encyclopedia of Alchemy
ERIC Educational Resources Information Center
Karpenko, Vladimir
1973-01-01
Describes a book containing the best illustrations in the history of alchemical literature, and is also considered unique because each of the 107 engravings is provided with a short Latin epigram explaining the sense of the picture. (DF)
ERIC Educational Resources Information Center
Deininger, Rolf A.; Berger, Carl F., Jr.
1983-01-01
Provides instructions for interfacing a pH meter directly to an Apple II microcomputer without an analog-to-digital converter. Includes program listing (with enough remark statements to make it self-documenting) in Integer Basic to display the pH readings. (Author/JN)
Performance Based Education: A Social Alchemy.
ERIC Educational Resources Information Center
Clements, Millard
1982-01-01
An exploration of performance-based education is focused through these questions: What image of human beings does it project? What image of professionals does it project? What purpose does it serve? What image of knowledge does it project? (CT)
Some considerations concerning the alchemy of the De anima in arte alchemiae of pseudo-Avicenna.
Moureau, Sébastien
2009-03-01
This article explains some essential features of the alchemical doctrine of the De anima in arte alchemiae, a treatise written in Spain during the twelfth century (in Arabic, but only the Latin translation remains), and wrongly attributed to Avicenna. It shows that pseudo-Avicenna uses alchemical principles and elixir theory directly inspired by Jabirian texts, and classification of materials influenced by al-Razi. The alchemy of pseudo-Avicenna is entirely based on operations on the four elements: the alchemist has to reduce hair, blood or eggs to their elements, and isolate one of their essential properties (warmth, coldness, moisture and dryness), so that he can change the proportion of essential properties of the body he wants to transmute into gold or silver. The preparation made from hair, blood or eggs (the isolated property) is what he calls the elixir.
Novel Catalysis by Gold: A Modern Alchemy
NASA Astrophysics Data System (ADS)
Haruta, Masatake
Gold has long been neglected as a catalyst because of its chemical inertness. However, when gold is deposited as nanoparticles on carbon and polymer materials as well as on base metal oxides and hydroxides, it exhibits unique catalytic properties for many reactions such as CO oxidation at a temperature as low as 200 K, gas phase direct epoxidation of propylene, and aerobic oxidation of glucose to gluconic acid. The structure-catalytic activity correlations are discussed with emphasis on the contact structure, support selection, and the size control of gold particles. Gold clusters with diameters smaller than 2 nm are expected to exhibit novel properties in catalysis, optics, and electronics depending on the size (number of atoms), shape, and the electronic and chemical interaction with the support materials. The above achievements and attempts can be regarded as a modern alchemy that creates valuables by means of the noblest element with little practical use.
Clucas, Stephen
2017-05-01
John Dee's Monas Hieroglyphica (1564) was a work which involved a close collaboration between its author and his "singular friend" the Antwerp printer Willem Silvius, in whose house Dee was living whilst he composed the work and saw it through the press. This article considers the reasons why Dee chose to collaborate with Silvius, and the importance of the intellectual culture - and the print trade - of the Low Countries to the development of Dee's outlook. Dee's Monas was probably the first alchemical work which focused exclusively on the diagrammatic representation of the alchemical process, combining diagrams, cosmological schemes, and various forms of tabular grid. It is argued that in the Monas the boundaries between typography and alchemy are blurred as the diagrams "anatomising" his hieroglyphic sign (the "Monad") are seen as revealing truths about alchemical substances and processes.
Neven, Sylvie
2016-01-01
In the Middle Ages and the premodern period knowledge of alchemical practices and materials was transmitted via collections of recipes often grouped concomitantly with art-technological instructions. In both alchemy and chemical technology particular importance is placed on artisanal and craft practices. Both are concerned with the description of colours. Both require procedures involving precise and specifically defined actions, prescriptions and ingredients. Assuming that alchemical and artistic texts have the same textual format, this raises the question: were they produced, diffused and read by the same people? This paper investigates the authorship and the context of production behind a sample of German alchemical manuscripts dating from the fourteenth to the sixteenth century. It scrutinizes their process of production, compilation and dissemination. This paper also sheds light on the various types of marginalia, and correlates them with their diverse functions. It thus delivers significant information about the readers and users of these manuscripts.
Chemistry Teaching: Science or Alchemy?
ERIC Educational Resources Information Center
Johnstone, A. H.
1997-01-01
Suggests that the development of good chemistry teaching and the pursuit of research have essentially the same structure. Similarities include the need for a clear focus, efficiency in time and effort, and a direction that is more often right than wrong. (DDR)
Paradigms and Plastic Facts in the History of Valence.
ERIC Educational Resources Information Center
Zavaleta, David
1988-01-01
Traces the development of bonding theory and notes the influence of preconceived theory upon this development. Considers ideas of alchemy, Newton, Dalton, Lewis, and quantum mechanics. Suggests a move away from conservative descriptive approaches of bonding theory. (ML)
ERIC Educational Resources Information Center
Seaborg, Glenn T.
1983-01-01
Reviews the historical development of the periodic table, examining major changes due to understanding of radioactivity, synthetic transmutation by bombardment, differences between transuranium elements and the lanthanide series, and the transactinide elements. Discusses the continuing work on atomic synthesis and its importance in extending our…
ERIC Educational Resources Information Center
Oliver, B. M.
1973-01-01
Discusses the origin of life on the basis of information about cosmic evolution, stellar alchemy, atmospheric histories, and rise and fall of civilizations. Indicates that man's contact with other civilizations in our galaxy may be made possible through studies of interstellar communication. (CC)
NASA Astrophysics Data System (ADS)
Cassé, Michel; Lyle, Translated by Stephen
2003-08-01
Preface; 1. Nuclear astrophysics: defence and illustration; 2. Light from atoms, light from the sky; 3. Visions; 4. Contents of the sky: atomic sources and fountains; 5. Nuclear suns; 6. Sociology of stars and clouds; 7. Histories; 8. Ancient stars in the galactic halo; 9. Conclusion; Appendices.
The Paranormal: A Selected Bibliography of Serials and Reference Works, with Commentary.
ERIC Educational Resources Information Center
Smith, Charles H.
1997-01-01
Provides bibliography of references and serials to assist acquisitions librarians in selection of the paranormal. Topics include alchemy, astrology, magic, conjuring, witchcraft, paganism, demonology, satanism, voodooism, sorcery, cults, shamanism, UFOs, exobiology, curious physical and biological phenomena, ghosts, poltergeists, haunted places,…
Information Alchemy: Transforming Information through Knowledge Utilization.
ERIC Educational Resources Information Center
Backer, Thomas E.
1993-01-01
Provides an overview of knowledge utilization, what it encompasses, and its three waves of activity in America. Basic principles and strategies to consider are listed, and an example of how knowledge utilization is applied by the Center for Mental Health Services is given. (17 references) (EA)
Moral alchemy: How love changes norms.
Magid, Rachel W; Schulz, Laura E
2017-10-01
We discuss a process by which non-moral concerns (that is concerns agreed to be non-moral within a particular cultural context) can take on moral content. We refer to this phenomenon as moral alchemy and suggest that it arises because moral obligations of care entail recursively valuing loved ones' values, thus allowing propositions with no moral weight in themselves to become morally charged. Within this framework, we predict that when people believe a loved one cares about a behavior more than they do themselves, the moral imperative to care about the loved one's interests will raise the value of that behavior, such that people will be more likely to infer that third parties will see the behavior as wrong (Experiment 1) and the behavior itself as more morally important (Experiment 2) than when the same behaviors are considered outside the context of a caring relationship. The current study confirmed these predictions. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.
Chemistry in "The Ascent of Man."
ERIC Educational Resources Information Center
Hostettler, John D.; Brooks, Kenneth
1980-01-01
Describes "The Ascent of Man," a course emphasizing science and human values. Detailed are some chemical topics covered in the course, and how these topics are used in other traditional chemistry courses. Topics discussed include alchemy, the chemical revolution, steam engines, the Manhattan project, and several bioethical problems. (CS)
The Prophetic Voice in Jeremy Rifkin's "Algeny."
ERIC Educational Resources Information Center
Sullivan, Dale
1990-01-01
Argues that Jeremy Rifkin's "Algeny" is epideictic rhetoric, related to the European "Jeremiad," a traditional lamentation mode. Notes that Rifkin draws a parallel between genetic engineering and alchemy and adopts a world view dominated by a static hierarchy. Suggests that the teaching of the epideictic genre underscore both…
Accreditation's Alchemy Hour: Riding the Wave of Innovation
ERIC Educational Resources Information Center
Gaston, Paul L.
2014-01-01
This article was adapted from Paul L. Gaston's address to the 2014 annual meeting of the "Association of American Colleges and Universities." The panel session talk "Accreditation: Riding the Wave of Innovation--or Going Under?" addressed issues surrounding the many proposals for demolishing and rebuilding higher education…
Knowledge and Technology: Sharing With Society
NASA Astrophysics Data System (ADS)
Benvenuti, Cristoforo; Sutton, Christine; Wenninger, Horst
The following sections are included: * A Core Mission of CERN * Medical Accelerators: A Tool for Tumour Therapy * Medipix: The Image is the Message * Crystal Clear: From Higgs to PET * Solar Collectors: When Nothing is Better * The TARC Experiment at CERN: Modern Alchemy * A CLOUD Chamber with a Silvery Lining * References
Rhythmical Alchemy: Village Drumming with Arthur Hull.
ERIC Educational Resources Information Center
Hillerson, Gary R.; Hull, Arthur
As a step toward writing a master's thesis in psychology, the connection between rhythm circles and psychotherapeutic process was explored. Arthur Hull, who experienced and preached about the healing power of rhythm for many years, was interviewed. This article recorded the interview between Arthur and the researcher. The interviewer learned that…
Enculturation, Not Alchemy: Professionalizing Novice Writing Program Administrators.
ERIC Educational Resources Information Center
Peters, Bradley
1998-01-01
Discusses a process of acculturation in three stages by which fledgling Writing Program Administrators can be transformed into change agents: (1) critically reading the program to locate key allies, potential advocates, and proven adversaries; (2) implementing changes on an infrastructural level to convert positive relations among colleagues into…
Building Budgets and Trust through the Alchemy of Superintendent Leadership
ERIC Educational Resources Information Center
Bird, James J.
2010-01-01
Superintendents have the burden and the opportunity to exert leadership through the budget-building process. This article details a dozen tenets which can be implemented by practicing superintendents. Doing so increases the chances of building trust among the stakeholders of administrators, staff, community, and school board members. The district…
The Use of Molecular Modeling Programs in Medicinal Chemistry Instruction.
ERIC Educational Resources Information Center
Harrold, Marc W.
1992-01-01
This paper describes and evaluates the use of a molecular modeling computer program (Alchemy II) in a pharmaceutical education program. Provided are the hardware requirements and basic program features as well as several examples of how this program and its features have been applied in the classroom. (GLR)
Evaluating the Reliability, Validity, and Usefulness of Education Cost Studies
ERIC Educational Resources Information Center
Baker, Bruce D.
2006-01-01
Recent studies that purport to estimate the costs of constitutionally adequate education have been described as either a "gold standard" that should guide legislative school finance policy design and judicial evaluation, or as pure "alchemy." Methods for estimating the cost of constitutionally adequate education can be roughly…
Silver to Gold: The Alchemy, Potential, and Maturing of ACES and CES.
ERIC Educational Resources Information Center
Engels, Dennis W.; Muro, James J.
1986-01-01
Exponential changes in Western and international society and in American and international education afford promise, opportunity, and challenges for tomorrow's counselor. Leadership in services, teaching, research, credentialing, policy, and law all seem to be areas of potential contribution and growth for the counselors, counselor educators, and…
Feminizing Science: The Alchemy of Title IX
ERIC Educational Resources Information Center
Hausman, Patricia
2008-01-01
The author scrutinizes the National Academy of Sciences report "Beyond Bias and Barriers: Fulfilling the Potential of Women in Academic Science and Engineering" and its dangerous call to place the sciences under the sledgehammer of Title IX. Her findings: A one-sided, inaccurate, and internally contradictory report prepared by a…
ERIC Educational Resources Information Center
Cobb, Brian T.; Hanna, John P.
1998-01-01
In the process of restructuring its debt and taking on additional debt, Franklin Pierce College (New Hampshire) accepted the consequences of a downgrade in its investment-grade rating. This resulted in a successful bond sale, with bonds carrying an insured single-A rating. Events leading up to the restructuring and credit issues considered by the…
The Alchemy of Action Learning
ERIC Educational Resources Information Center
West, Penny; Choueke, Richard
2003-01-01
This paper examines the authors' experiences as action learning set facilitators within a public sector organisation undergoing change. Our objectives were to assist in the identification of internal and external drivers for change and to work with the set to explore how people's roles and responsibilities might be enhanced and developed in a…
Alchemy in Iowa: Arts Education at Harding Junior High School.
ERIC Educational Resources Information Center
Vallance, Elizabeth
1991-01-01
Case study of an Iowa junior high school describes how the school and community identified their resources and used them to create successful arts education programs from ordinary resources. The article examines four types of commitment that shaped school practice, noting effective teaching practices and administrative policy. (SM)
Quantum Theory, the Uncertainty Principle, and the Alchemy of Standardized Testing.
ERIC Educational Resources Information Center
Wassermann, Selma
2001-01-01
Argues that reliance on the outcome of quantitative standardized tests to assess student performance is misplaced quest for certainty in an uncertain world. Reviews and lauds Canadian teacher-devised qualitative diagnostic tool, "Profiles of Student Behaviors," composed of 20 behavioral patterns in student knowledge, attitude, and skill.…
Of Alchemy and Authenticity: Teaching about Daoism Today
ERIC Educational Resources Information Center
Miller, James; Siegler, Elijah
2007-01-01
The authors discuss the complexities and responsibilities of teaching about Daoism in contemporary North American colleges and universities. Expanding and revising the findings of Kirkland (1998), they argue that enough has changed in educational and cultural contexts to warrant new strategies for teaching about Daoism. Textbooks are now available…
The Tao of Teaching: Romance and Process.
ERIC Educational Resources Information Center
Schindler, Stefan
1991-01-01
Because college teaching aims to elevate, not entertain, it must be nourished and appreciated as a pedagogical alchemy mixing facts and feelings, ideas and skills, history and mystery. The current debate on educational reform should focus more on quality of learning experience, and on how to create and sustain it. (MSE)
The Alchemy of Mathematical Experience: A Psychoanalysis of Student Writings.
ERIC Educational Resources Information Center
Early, Robert E.
1992-01-01
Shares a psychological look at student images of mathematical learning and problem solving through students' writings about mathematical experiences. The analysis is done from a Jungian psychoanalytic orientation with the goal of assisting students develop a deeper perspective from which to view their mathematics experience. (MDH)
ERIC Educational Resources Information Center
Mayes, Clifford
2003-01-01
In order for teachers to reflect deeply upon themselves, they need powerful models and images to guide their introspection. In teacher reflectivity, as in the therapeutic processes, psychic energy must ultimately be "contained" by models and modalities that enable one to make sense out of one's inner and outer experiences. This enables those…
Dynamic Human-Computer Collaboration in Real-time Unmanned Vehicle Scheduling
2010-06-01
Rarely play games Play games once a month Weekly gamer A few times a week gamer Daily gamer Types of games played: 9. Rate...Algorithm, Alchemy , or Apostasy?," International Journal of Human-Computer Studies, vol. 52, pp. 203-216, 2000. [52] J.-M. Hoc, "From Human
ERIC Educational Resources Information Center
Gannon, Susanne
2012-01-01
This paper explores the metaphor of the classroom as a "crucible" for early professional learning where beginning teachers forge professional identities in complex, unpredictable, paradoxical, affectively and physically potent contexts of practice. It works into the dissonances and contradictions of the micro-narratives embedded in the…
Whose Voice Is It Anyway? Rodriguez' Speech in Retrospect.
ERIC Educational Resources Information Center
Villanueva, Victor Jr.
1987-01-01
Questions Richard Rodriguez' position that linguistic assimilation for minorities is like alchemy, creating something new and greater than what was. Concludes that it is better for teachers to teach students to use the conventions of standard discourse without accepting the ideology of those for whom the standard dialect is the language of…
Education and Alchemy: The Story of Wyndham Science.
ERIC Educational Resources Information Center
Alexander, A. E.
This is a critical account of the introduction of a new science curriculum in New South Wales, Australia. The introduction of the new courses is contrasted with methods used to update science courses in other countries and in other Australian States. Reactions from teachers, students, and the public are reported. Statements by the curriculum…
ERIC Educational Resources Information Center
Serret, Natasha
2010-01-01
Traditionally, alchemy has involved the power of transmuting base metals such as lead into gold or producing the "elixir of life" for those wealthy people who wanted to live forever. But what of today's developments? One hundred years ago, even breaking the four-minute mile would have been deemed "magic," which is what the alchemists of the past…
Transformation in Higher Education: The Inevitable Union of Alchemy and Technology
ERIC Educational Resources Information Center
Harpur, John
2006-01-01
From the first time that humans drew together in learned groups of scholars and disciples, questions have been raised about the purpose, sustainability and values of such gatherings. The development of information technologies together with mass participation in Higher Education has sharpened disputes between innovation and tradition like never…
Courtroom Alchemy: Adequacy Advocates Turn Guesstimates into Gold
ERIC Educational Resources Information Center
Guthrie, James W.; Springer, Matthew G.
2007-01-01
Beginning in the late 1960s, and accelerating unabated through to the present, plaintiffs have filed more than 125 court cases questioning the constitutionality of school district and school spending levels. Much of the litigation, particularly early on, centered on the issue of funding "equity." Few would seek to deny American public school…
Constructing Core Journal Lists: Mixing Science and Alchemy.
ERIC Educational Resources Information Center
Corby, Katherine
2003-01-01
Via an overview of core journal studies, emphasizing the social sciences and education, this review looks for best practices in both motivation and methodology. Selection decisions receive particular focus. Lack of correlation between methods is indicative of the complexity of the topic and the need for judgment in design and use. (Author)
Alchemies and Governing: Or, Questions about the Questions We Ask
ERIC Educational Resources Information Center
Popkewitz, Thomas S.
2007-01-01
This article turns one of most cited philosopher's John Dewey's title, "How We Think" (1933/1998) back upon itself to consider how "thought" or "reason" are cultural practices that historically order and generate principles for reflection and action. The discussion proceeds thusly: (1) Schooling is about changing people; (2) Changing people…
ERIC Educational Resources Information Center
Diaz Pineiro, Odalys Maria
2010-01-01
Practice and inquiry into school-community connections have been guided by problematic assumptions about the role of neighborhood schools, community based institutions, and local economic development policies in the evolution of urban communities. Formal relationships between schools and urban neighborhoods grounded in these assumptions have been…
ERIC Educational Resources Information Center
Gibbins, Thor
2013-01-01
This study explores the experiences of undergraduate students enrolled in an education I-Series (University of Maryland undergraduate courses designed to inspire innovation, imagination, and intellect) course, Good Stories: Teaching Stories for Peace and Justice. In this course students are asked to produce digital stories that project themes of…
Alchemy and uncertainty: What good are models?
F.L. Bunnell
1989-01-01
Wildlife-habitat models are increasing in abundance, diversity, and use, but symptoms of failure are evident in their application, including misuse, disuse, failure to test, and litigation. Reasons for failure often relate to the different purposes managers and researchers have for using the models to predict and to aid understanding. This paper examines these two...
Establishing the Canon: George Ripley and his alchemical sources.
Rampling, Jennifer M
2008-11-01
George Ripley, Canon of Bridlington (ca. 1415 to ca. 1490) was one of England's most famous alchemists, whose alchemical opera attracted study and commentary throughout the sixteenth and seventeenth centuries, and were printed and translated both in England and abroad. Yet Ripley's frequently baffling texts have proved resistant to scholarly interpretation. This paper attempts to unravel some of Ripley's alchemical theories and practice, firstly by identifying his major sources, and secondly by gauging his response to these texts. For instance, although Ripley's interest in the corpus of alchemical texts pseudonymously attributed to Ramon Lull is well documented, it transpires that his best known work, the Compound of Alchemy, or Twelve Gates, is actually based not on a Lullian work, but on a Latin treatise that Ripley attributed to the little-known alchemist, Guido de Montanor. Further clues to Ripley's alchemical thought can be obtained by considering his handling of a potential conflict between his two authorities, Lull and Guido. The resulting insights into Ripley's alchemy provide an instrument for assessing which of Ripley's pseudoepigraphic works can be truly called "canonical".
Digital Alchemy for Materials Design: Colloids and Beyond
NASA Astrophysics Data System (ADS)
van Anders, Greg; Klotsa, Daphne; Karas, Andrew; Dodd, Paul; Glotzer, Sharon
Starting with the early alchemists, a holy grail of science has been to make desired materials by manipulating basic building blocks. Building blocks that show promise for assembling new complex materials can be synthesized at the nanoscale with attributes that would astonish the ancient alchemists in their versatility. However, this versatility means that connecting building-block attributes to bulk structure is both necessary for rationally engineering materials and difficult because building block attributes can be altered in many ways. We show how to exploit the malleability of colloidal nanoparticle ``elements'' to quantitatively link building-block attributes to bulk structure through a statistical thermodynamic framework we term ``digital alchemy''. We use this framework to optimize building blocks for a given target structure and to determine which building-block attributes are most important to control for self-assembly, through a set of novel thermodynamic response functions. We thereby establish direct links between the attributes of colloidal building blocks and the bulk structures they form. Moreover, our results give concrete solutions to the more general conceptual challenge of optimizing emergent behaviors in nature and can be applied to other types of matter.
NASA Astrophysics Data System (ADS)
Jia, S.; Bud'Ko, S. L.; Samolyuk, G. D.; Canfield, P. C.
2007-05-01
One of the historic goals of alchemy was to turn base elements into precious ones. Although the practice of alchemy has been superseded by chemistry and solid-state physics, the desire to dramatically change or tune the properties of a compound, preferably through small changes in stoichiometry or composition, remains. This desire becomes even more compelling for compounds that can be tuned to extremes in behaviour. Here, we report that the RT2Zn20 (R=rare earth and T=transition metal) family of compounds manifests exactly this type of versatility, even though they are more than 85% Zn. By tuning T, we find that YFe2Zn20 is closer to ferromagnetism than elemental Pd, the classic example of a nearly ferromagnetic Fermi liquid. By submerging Gd in this highly polarizable Fermi liquid, we tune the system to a remarkably high-temperature ferromagnetic (TC=86K) state for a compound with less than 5% Gd. Although this is not quite turning lead into gold, it is essentially tuning Zn to become a variety of model compounds.
NASA Astrophysics Data System (ADS)
Esteban, C.; García López, R. J.; Herrero, A.; Sánchez, F.
2004-03-01
1. Primordial alchemy: from the Big Bang to the present Universe G. Steigman; 2. Stellar nucleosynthesis N. Langer; 3. Obervational aspects of stellar nucleosynthesis D. L. Lambert; 4. Abundance determinations in HII regions and planetary nebulae G. Stasinska; 5. Element abundances in nearby galaxies D. R. Garnett; 6. Chemical evolution of galaxies and intracluster medium F.Matteucci; 7. Element abundances through the cosmic ages M. Pettini.
NASA Astrophysics Data System (ADS)
Esteban, C.; García López, R. J.; Herrero, A.; Sánchez, F.
2011-01-01
1. Primordial alchemy: from the Big Bang to the present Universe G. Steigman; 2. Stellar nucleosynthesis N. Langer; 3. Obervational aspects of stellar nucleosynthesis D. L. Lambert; 4. Abundance determinations in HII regions and planetary nebulae G. Stasinska; 5. Element abundances in nearby galaxies D. R. Garnett; 6. Chemical evolution of galaxies and intracluster medium F.Matteucci; 7. Element abundances through the cosmic ages M. Pettini.
ERIC Educational Resources Information Center
Merritt, Brett W.
2013-01-01
Understanding is widely touted to be of paramount importance for education. This is especially true in science education research and development where understanding is heralded as one of the cornerstones of reform. Teachers are expected to teach for understanding and students are expected to learn with understanding. This dissertation is an…
The Alchemy of Art: Transforming Student Art into Science Knowledge in the Chemistry Classroom
ERIC Educational Resources Information Center
Flores, Mickie
2005-01-01
Art provides students a way to visually represent their scientific knowledge and at the same time helps teachers assess student understanding. Examining a drawing allows teachers to scrutinize students' mental model of a science concept. Science can be described as a continuing process of discovering the order and recurring patterns in nature;…
Bloody Mud, Rifle Butts, and Barbed Wire: Transforming the Bataan Death March in Silko's "Ceremony"
ERIC Educational Resources Information Center
Beidler, Peter G.
2004-01-01
Efforts made by Leslie Marmon Silko's who took factual raw materials and, through the alchemy of her creative artistry, transformed her novel, "Ceremony" into something new and different is presented. Silko has made certain changes in the Bataan Death March in "Ceremony", and portrayed the Japanese with considerable sympathy.
The Educational Leader's Alchemy: Creating the Gold Within
ERIC Educational Resources Information Center
Sytsma, Sandra
2009-01-01
In going ahead and showing the way, leading can be seen as a process of changing. The busyness of day-to-day leadership in schools and other educational facilities bears witness to the necessity of leaders' "thinking on their feet" as they strive to resolve multiple issues. However, the constant pressure or stress of this lifestyle has its price…
The Alchemy of "Costing Out" an Adequate Education
ERIC Educational Resources Information Center
Hanushek, Eric A.
2006-01-01
In response to the rapid rise in court cases related to the adequacy of school funding, a variety of alternative methods have been developed to provide an analytical base about the necessary expenditure on schools. These approaches have been titled to give an aura of a thoughtful and solid scientific basis: the professional judgment model, the…
The Alchemy of College Philanthropy: What Dynamics Inspire the Transformational Gift?
ERIC Educational Resources Information Center
Gallagher, Geraldine
2014-01-01
Modest inquiry exists to elucidate why donors make large contributions to community colleges. Of every charitable dollar donated to education, two-year colleges receive 2 to 4 cents. This grounded theory study included 30 major donors to 23 colleges in 18 states. The questions were comprehensive: why donors and how donors make major gifts;…
ERIC Educational Resources Information Center
Yonge, George D.
2008-01-01
In his response to Kruger, Le Grange claims that: (1) the South African discourse of fundamental pedagogics was closely allied with Christian National Education and functioned as a powerful educational doctrine in the service of the South African policy of apartheid education; (2) fundamental pedagogics bracketed political discourse; (3) the…
Spring 2005 Industry Study. Strategic Materials
2005-01-01
Research Laboratory, Weapons and Materials Research Center. Presented at ARL, Aberdeen, MD. March 17, 2005. Ashley, Steven. “ Alchemy of a...Spring 2005 Industry Study Final Report Strategic Materials The Industrial College of the Armed Forces National...the collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data
Theoretical and Experimental Investigation of Heterojunction Interfaces
1983-11-01
every two surface atoms at the junction. In terms of our theoretical alchemy one proton must be added for every two surface atoms. Note that this...Chye. I. Lindau. P PianetU, C. M. Gamer , and W E Spicer, Phys Rev. B 17, 2682 11978|. "J. R. Waldrop and R W. Grant. Appl. Phys. Lett. 34. 630
Inner Alchemy: Transforming Dilemmas in Education Through Mindfulness
ERIC Educational Resources Information Center
Burrows, Leigh
2015-01-01
This article reports on face-to-face and online qualitative research conducted with 25 teachers from 8 schools in Australia that explored their experience of mindfulness and reflection in relation to a self-identified relational dilemma with a student, colleague, or parent who was causing them concern at work. The aim of this study was to find out…
Small-diameter timber alchemy: can utilization pay the way toward fire-resistant forests
Jeremy S. Fried; R. Jamie Barbour; Roger D. Fight; Glenn Christensen; Guy Pinjuv
2008-01-01
There is growing interest in using biomass removed from hazardous fuels reduction treatments in wood-fired electrical generation facilities. An application of FIA BioSum to southwest Oregonâs Klamath ecoregion assessed the financial feasibility of fuel treatment and biomass generation under a range of product prices and fire hazard-motivated silvicultural prescriptions...
Green chemistry education in the Middle East
NASA Astrophysics Data System (ADS)
Kolopajlo, Larry
2017-06-01
The Middle East once dominated the age of alchemy, and today it is experiencing a resurgence by transforming the age of petroleum chemicals into a greener science through Estidama. This green conversion is taking place through green chemical research and education. This report examines and reviews the understudied subject of green chemical education in the Middle East through the lens of context and history.
The Untold Story: African American Women Administrators' Alchemy of Turning Adversity into Gold
ERIC Educational Resources Information Center
Barksdale, Sydney Howe
2007-01-01
As we approach the end of the first decade of the twenty-first century, the globalization and privatization of the academy is destabilizing the patterns of university professional work developed over the past hundred years (Slaughter and Leslie, 1997). To grasp the extent of changes taking place and to understand the forces of change on women in…
ERIC Educational Resources Information Center
Bonner, Fred A., II; Lewis, Chance W.; Bowman-Perrott, Lisa; Hill-Jackson, Valerie; James, Marlon
2009-01-01
This article focuses on the underrepresentation of African American males in gifted and talented programs, and offers a number of key recommendations to practitioners and researchers who seek viable strategies to circumvent this problem. Beyond the focus on underrepresentation, several additional topics for discussion are excogitated to provide a…
ERIC Educational Resources Information Center
Puig, Victoria I.
2012-01-01
This study was designed to gain insight into how early intervention (EI) services incorporate the cultural and linguistic resources of families and how EI professionals and families build partnerships with each other. Through observation and interview, the author looked deeply at the experiences of a small group of culturally and linguistically…
Transmutation of Matter in Byzantium: The Case of Michael Psellos, the Alchemist
ERIC Educational Resources Information Center
Katsiampoura, Gianna
2008-01-01
There is thus nothing paradoxical about the inclusion of alchemy in the ensemble of the physical sciences nor in the preoccupation with it on the part of learned men engaged in scientific study. In the context of the Medieval model, where discourse on the physical world was ambiguous, often unclear, and lacking the support of experimental…
Complexity Theory and Network Centric Warfare
2003-09-01
realms of the unknown. Defence thinkers everywhere are searching forward for the science and alchemy that will deliver operational success. CCRP...0188 Public reporting burden for the collection of information is estimated to average 1 hour per response, including the time for reviewing...instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send
The Alchemy of Learning and Work: Negotiating Learner Knowledge in a Global Society
ERIC Educational Resources Information Center
Dabic, Snezana
2008-01-01
This article explores issues of literacy and identity of skilled migrants in an educational context in Australia as a learning society. First, it concentrates on forms of knowledge imposed on the learner and looks at how new discourses shape the self. Next, it tests the validity of the four pillars of education in the life of the learner. The…
European Union’s Military Crisis Management: Challenges and Perspectives
2012-06-08
respond quickly and decisively, but “the curious alchemy of German leadership, Italian support for it, British limitation of it, [and] French ambition...EUROPEAN UNION’S MILITARY CRISIS MANAGEMENT: CHALLENGES AND PERSPECTIVES A thesis presented to the Faculty of the U.S. Army...Command and General Staff College in partial fulfillment of the requirements for the degree MASTER OF MILITARY ART AND SCIENCE General Studies
Marine Corps Readiness: The Costs of First-Term Dependency
2000-01-01
Marines always get the job done, and the Marines are the masters of unfailing alchemy which converts unoriented youths into proud, self-reliant...especially in localities with high off base housing costs. Finances and housing problems are at the root of many other problems which service...Marine Corps Readiness: The Cost of First-Term Dependency CSC 2000 Subject Area – Manpower Table of Contents Page DISCLAIMER
Gabrieli, Francesca; Rosi, Francesca; Vichi, Alessandra; Cartechini, Laura; Pensabene Buemi, Luciano; Kazarian, Sergei G; Miliani, Costanza
2017-01-17
Protrusions, efflorescence, delamination, and opacity decreasing are severe degradation phenomena affecting oil paints with zinc oxide, one of the most common white pigments of the 20th century. Responsible for these dramatic alterations are the Zn carboxylates (also known as Zn soaps) originated by the interaction of the pigment and the fatty acids resulting from the hydrolysis of glycerides in the oil binding medium. Despite their widespread occurrence in paintings and the growing interest of the scientific community, the process of formation and evolution of Zn soaps is not yet fully understood. In this study micro-attenuated total reflection (ATR)-FT-IR spectroscopic imaging was required for the investigation at the microscale level of the nature and distribution of Zn soaps in the painting Alchemy by J. Pollock (1947, Peggy Guggenheim Collection, Venice) and for comparison with artificially aged model samples. For both actual samples and models, the role of AlSt(OH) 2 , a jellifying agent commonly added in 20th century paint tube formulations, proved decisive for the formation of zinc stearate-like (ZnSt 2 ) soaps. It was observed that ZnSt 2 -like soaps first form around the added AlSt(OH) 2 particles and then eventually grow within the whole painting stratigraphy as irregularly shaped particles. In some of the Alchemy samples, and diversely from the models, a peculiar distribution of ZnSt 2 aggregates arranged as rounded and larger particles was also documented. Notably, in one of these samples, larger agglomerates of ZnSt 2 expanding toward the support of the painting were observed and interpreted as the early stage of the formation of internal protrusions. Micro-ATR-FT-IR spectroscopic imaging, thanks to a very high chemical specificity combined with high spatial resolution, was proved to give valuable information for assessing the conservation state of irreplaceable 20th century oil paintings, revealing the chemical distribution of Zn soaps within the paint stratigraphy before their effect becomes disruptive.
Zuber, Mike A
2018-05-01
By the time it was published in 1705, the Speculum Sapientiae claimed to have had a long history going back to 1672. However, the fact that exaggerated stories were commonplace in alchemical literature leads us to question its credibility. This paper explores the secret lives of this alchemical text prior to its print publication to clarify the roles of manuscripts in early-modern alchemy. Specifically, I argue that there were three aspects that could distinguish manuscript from print: provenance, materiality, and exclusivity. These can be seen at work in the fate of Johann Heinrich Vierordt, an itinerant alchemist and cavalry captain whose career is inextricably linked to the scribal dissemination of the Speculum Sapientiae. In addition to manuscript copies of that text at libraries across Europe, a significant cache of correspondence preserved in Gotha documents Vierordt's dealings with Duke Friedrich I of Saxe-Gotha. The verisimilitudinous provenance of Vierordt's alchemical secrets and tincture played a crucial role in allowing him to gain Friedrich's trust. Yet it was only after Vierordt presented him with a precious parchment manuscript of the Speculum Sapientiae that he truly succeeded in gaining the duke's patronage. Subsequently, reports of multiple conflicting copies surfacing in Amsterdam sealed Vierordt's fall from favour.
Legends about Legends: Abraham Eleazar's Adaptation of Nicolas Flamel.
Priesner, Claus
2016-02-01
This paper explores the relationship between three illustrated alchemical treatises, all of which are associated with Jewish adepts: the famous Le Livre des figures hieroglyphiques attributed to Nicolas Flamel, and two treatises published in 1735 in Erfurt-the Uraltes Chymisches Werckh and the Donum Dei. The Werckh is supposedly written by Rabbi Abraham Eleazar, while the Donum Dei is attributed to an ancient alchemist-cabalist, Rabbi Samuel Baruch. I argue that these authors are fictitious, and that both works were in fact written in the early eighteenth century by their supposed editor, the probably pseudonymous Julius Gervasius. Gervasius connects the Werckh with the legend of Nicolas Flamel by suggesting that it is based on the original, Jewish manuscript which helped Flamel to find the Stone of the Sages. Gervasius used various strategies to confer a sense of Jewish "authenticity" on these works, borrowing from contemporary (non-Jewish) perceptions of Jewish ritual, Hebrew language, and Christian Cabala. The Werckh also borrows and adapts a sequence of allegorical illustrations from those in pseudo-Flamel's Livre, and I compare the two sets of figures and, where possible, interpret them. I conclude that the later works in fact teach us far more about the state of alchemy in the seventeenth and eighteenth centuries than they do about either medieval alchemy or Judaism.
Science, alchemy and light: paintings by Joseph Wright of Derby.
Dominiczak, Marek H
2002-01-01
This article considers two paintings by the English painter, Joseph Wright of Derby (1734-97), 'An Experiment on a Bird in the Air Pump' and 'The Alchemist in Search of the Philosopher's Stone' as painterly reflections on the early industrial culture. Particularly interesting in the "Experiment on a Bird" is the broad spectrum of spectator's reactions to the experiment; this can be related to the contemporary debate on the contextualization of science.
United States Special Operations Command Professional Military Education
2013-12-01
Performance and potential are the alchemy of this growth, but nothing ensures that they are properly prepared leaders more than the care given to the...for Army Special Operations officers. This is in line with this project’s research question and the proposal for a SOCOM holistic approach to PME. 4...level PME as “sending a doctor to a dental academy.”36 F. KNOWLEDGE, SKILLS, AND ABILITIES Question Three asked which specific knowledge, skills
Thiesen, Wilfred
2008-07-01
John Dastin, a noted alchemist who lived ca. 1300, followed the lead of many of his contemporaries and predecessors in using letters to propagate his views on alchemy. This article identifies a number of letters that Dastin wrote, and includes one text addressed to a cardinal of the city of Naples. This letter is virtually a copy of a work by Arnold of Villanova. I believe that other works ascribed to Dastin will also show a great dependence on Arnold's works.
[The use of honey in the simple and composed drugs at Rhazés].
Katouzian-Safadi, Mehrnaz; Bonmatin, Jean-Marc
2003-01-01
Rāzī or Rhazès for Latin people is one of the great scientists of ninth century. He left major works in medicine, pharmacy and in alchemy. We examine here, the use of honey by this scientist as a simple drug and as one of the essential substances included in composed medicines. That leads us to examine the notion of simple and of composed in this physician and alchemist.
LEAD AND MERCURY EACH AS PRIME MATTER IN ALCHEMY
Mahdihassan, S.
1988-01-01
Prime Matter is matter-cum-energy. The first substance identified as such was lead. When gently heated it becomes red and redness means soul or energy so that lead was potentially red or soul-like and as such dual natured. Mercury also becomes red and can return to white metal. It was thus dual natured and was the second substance recognized as Prime Matter. First lead alone and then lead and mercury were considered as the source of all metals. PMID:22557603
The Coast Artillery Journal. Volume 72, Number 5, May 1930
1930-05-01
the JOURNAL’Swelfare. ’rVeare pleased to learn that it is increasing its goodwill at Barrancas. Let us hope that the arts of alchemy ,vill be practiced...R. MILLER, C. A. C Business Manager Yolume 72 May, 1930 CONTENTS Number 5 MAJOR GENERAL JOHN W. GULICK. Frontispiece GREETINGS OF CHIEF OF COAST...ARTILLERY TO CORPS 381 MAJOR GENERAL JOHN W. GULICK, CHIEF OF COAST ARTILLERY 382 COMMENTS ON REVISION OF TR 535..55, COAST ARTILLERY TAR- GET PRACTICE
2012-02-01
used to finance 11. Changes in the output gap affect unemployment gradually over several quarters. Initially, part of a rise in output shows up as...discussion of the long-run effects of other debt- financed policies for boosting output and employment, see statement of Douglas W. Elmendorf, Director...DECEMBER 2011 CBO 6. See Eric M. Leeper, "Monetary Science, Fiscal Alchemy " (paper presented at the Federal Reserve Bank of Kansas City symposium
Budgeting for the Nation’s Defense Following the End of National Conflicts
2009-06-01
anticipation of the probable and preparation for the possible. It is, in a word, alchemy ; a method of transmutation from idea into action.”8 These...this combination, Congress disbanded the army at the end of the Revolutionary War due to financial concerns as the war had resulted in “the finances ...BUDGETING FOR THE NATON’S DEFENSE FOLLOWING THE END OF NATIONAL CONFLICTS BY CRAIG A. HARDING A THESIS PRESENTED TO THE FACULTY OF THE
Practising alchemy: the transmutation of evidence into best health care.
Goodyear-Smith, Felicity
2011-04-01
Alchemy was the synthesis or transmutation of all elements in perfect balance to obtain the philosopher's stone, the key to health. Just as alchemists sought this, so health practitioners always seek the best possible practice for optimal health outcomes for our patients. Best practice requires full knowledge--a little information can be dangerous. We need to serve our apprenticeship before we master our profession. Our profession is about improving health care. While the journey may start at medical school, the learning never ceases. It is not only about practising medicine, it is about the development of the practitioner. Professional practice requires systematic thinking combined with capacity to deal morally and creatively in areas of complexity and uncertainty appropriate to a specific context. It requires exemplary communication skills to interact with patients to facilitate collaborative decision making resulting in best practice. The synthesis of scientific and contextual evidence is a concept which applies to all disciplines where theoretical knowledge needs to be transferred to action to inform best practice. Decisions need to be made which take into account a complex array of factors, such as social and legal issues and resource constraints. Therefore, journey towards best practice involves transmutation of these three elements: scientific knowledge, the context in which it is applied and phronesis, the practical wisdom of the practitioner. All science has its limitations and we can never know all possible contextual information. Hence, like the philosopher's stone, best practice is a goal to which we aspire but never quite attain.
Synthesis and analgesic activity of some side-chain modified anpirtoline derivatives.
Rádl, S; Hezky, P; Proska, J; Hejnová, L; Krejcí, I
2000-05-01
New derivatives of anpirtoline and deazaanpirtoline modified in the side chain have been synthesized. The series includes compounds 3 with side-chains containing piperidine or pyrrolidine rings, compounds 4 containing 8-azabicyclo[3.2.1]octane moiety, and compounds 5 having piperazine ring in their side-chains. Their receptor binding profiles (5-HT1A, 5-HT1B) and analgesic activity (hot plate, acetic acid induced writhing) have been studied. Optimized structures (PM3-MOPAC, Alchemy 2000, Tripos Inc.) of the synthesized compounds 3-5 were compared with that of anpirtoline.
Color and symbology: symbolic systems of color ordering
NASA Astrophysics Data System (ADS)
Varela, Diana
2002-06-01
Color has been used symbolically in various different fields, such as Heraldry, Music, Liturgy, Alchemy, Art and Literature. In this study, we shall investigate and analyse the structures of relationships that have taken shape as symbolic systems within each specific area of analysis. We shall discuss the most significant symbolic fields and their systems of color ording, considering each one of them as a topological model based on a logic that determines the total organization, according to the scale of reciprocities applied, and the cultural context that gives it meaning.
Walters, Lisa
2010-01-01
This article explores Margaret Cavendish's depictions of alchemy, witchcraft and fairy lore in her scientific treatise Philosophical Letters and in fictional texts from Natures Pictures and Poems and Fancies. Though Cavendish was a dedicated materialist, she appropriates theories of magic from early modern science and folklore into her materialist epistemology. As Cavendish draws upon a fusion of early modern conceptions of magic, she creates a radical theory of matter which not only challenges patriarchy and binary oppositions, but also explores the plurality and mystery that can exist within an infinitely complex material world.
Walter Odington's De etate mundi and the Pursuit of a Scientific Chronology in Medieval England.
Nothaft, Carl Philipp
2016-01-01
This article deals with a forgotten treatise on the age of the world, written between 1308 and 1316 by Walter Odington, a monk of Evesham Abbey, otherwise known for his writings on alchemy and music theory. By tracing the sources and rationale behind Odington's arguments and comparing them with those of other medieval authors, the article attempts to shed new light on the state of chronological scholarship in England in the eleventh to fourteenth centuries, when astronomical and astrological methods were freely used to supplement or replace scriptural interpretation, yielding creative and unexpected results.
The I Ching and the psyche-body connection.
Ma, Shirley S Y
2005-04-01
Carl G. Jung's fateful meeting with Richard Wilhelm in 1929 has helped to build a bridge of depth psychological understanding between the East and the West. When Jung emerged from his 'confrontation with the unconscious', he felt validated by Wilhelm in his discovery of the healing power of medieval alchemical symbolism for the European psyche. Analytical psychology however offers a scientific, psychological understanding of Chinese wisdom as contained in the I Ching and Taoist alchemy. The Taoist alchemical tradition (also known as the Inner Elixir tradition of which 'The Secret of the Golden Flower' is a sample text) is based on the premise that psychological experience of the Tao can be achieved through mental and physiological means such as breathing and meditative techniques, gymnastics, dietary regimens such as fasting, consumption of medicinal herbs and minerals, and special sexual practices. This tradition incorporates the I Ching and traditional Chinese medicine in the alchemical opus. Taoist alchemy assumes the primacy of the physical body in the process of self-realization. The psychological and cosmic forces of the trigrams of the I Ching are stored in the internal organs of the body and are the basic material for the experience of Tao. The internal organs are the foundation of the material and subtle bodies and through cultivation, the body becomes spiritualized as the spirits are embodied. The body as a reflection of the entire cosmos becomes the residence of the gods. The realization of a new consciousness is symbolized by the hexagram Fu, meaning rebirth. The Chinese notion of Tao coincides with Jung's postulation of the unus mundus, the unity of existence which underlies the duality of psyche and matter, the psycho-physical background of existence. In this light, in the world of inner experience, East and West follow similar paths symbolically.
Ab initio calculations of the photoionization of diatomic molecules
NASA Astrophysics Data System (ADS)
Lefebvre-Brion, Helene; Raşeev, Georges
2003-01-01
A review is presented of the calculation of photoionization spectra, particularly in the spectral range where electron autoionization of diatomic molecules takes place. In addition to some interesting results obtained over years that compare favourably with experiment, the emphasis here is put on the relation between the methods developed for the calculation of observables associated with the continuum energy spectrum of the electrons and the Alchemy system of programs. This system of programs serves as a basis for initial and intermediate calculations. The examples presented show that diatomic molecules not only in gas phase but also oriented in space or physisorbed at surfaces may be studied readily.
Muonic alchemy: Transmuting elements with the inclusion of negative muons
NASA Astrophysics Data System (ADS)
Moncada, Félix; Cruz, Daniel; Reyes, Andrés
2012-06-01
In this Letter we present a theoretical study of atoms in which one electron has been replaced by a negative muon. We have treated these muonic systems with the Any Particle Molecular Orbital (APMO) method. A comparison between the electronic and muonic radial distributions revealed that muons are much more localized than electrons. Therefore, the muonic cloud is screening effectively one positive charge of the nucleus. Our results have revealed that by replacing an electron in an atom by a muon there is a transmutation of the electronic properties of that atom to those of the element with atomic number Z - 1.
The catalogue of the Ripley Corpus: alchemical writings attributed to George Ripley (d. ca. 1490).
Rampling, Jennifer M
2010-07-01
The period 1471 to 1700 saw the accretion of a large corpus of alchemical works associated with the famous English alchemist George Ripley, Canon of Bridlington (d. ca. 1490). Evaluation of Ripley's alchemy is hampered by uncertainty over the composition of the corpus, the dating and provenance of individual texts, and the difficulty of separating genuine from spurious attributions. The Catalogue of the Ripley Corpus (CRC) provides a first step in ordering these diverse materials: a descriptive catalogue of approximately forty-five alchemical treatises, recipes and poems attributed to Ripley, with an index of all known manuscript copies.
Lighting market alchemy: Will we find a pot of gold at the end of the III-V rainbow?
NASA Astrophysics Data System (ADS)
Conway, Kathryn M.
2004-12-01
With a focus on visible spectrum light emitting diodes (LEDs), three questions frame this update. First, what are the market and financial outlooks for light-producing compound semiconductor materials and devices? Second, which applications offer the greatest growth potential for the next five to ten years and with which technologies will they likely compete for market share? Third, how can photonics experts contribute to accelerated successes for LEDs and other solid-state lighting technologies such as quantum dots? Using the rainbow as a metaphor for the market, the author examines developments in single color, multiple color and "white light" products.
Descartes, Cardiac Heat, and Alchemy.
Heitsch, Dorothea
2016-11-01
René Descartes (1596-1650) insisted on a heat and light theory to explain cardiac movement, and used concepts such as distillation of the vital spirits, fermentation in the digestive process, and fermentation in the circulation of the blood. I argue that his theory of the body as a heat-exchange system was based on alchemical and natural philosophical notions of fire and light expounded by precursors and contemporaries who included Jean D'Espagnet, Jean Fernel, Jan Baptist van Helmont, and Andreas Libavius. Descartes endeavoured to mechanise their approaches, creating a theory in which fire and heat, a legacy from thermal explanations of physiology, were transformed into alchemical fire, and then into mechanistic or physicalist heat.
Creating new β cells: cellular transmutation by genomic alchemy.
Moss, Larry G
2013-03-01
To address insulin insufficiency, diabetes research has long focused on techniques for replacing insulin-producing β cells. Studies in mice have suggested that, under some conditions, α cells possess the capacity to transdifferentiate into β cells, although the mechanisms that drive this conversion are unclear. In this issue, Bramswig et al. analyzed the methylation states of purified human α, β, and acinar cells and found α cells exhibit intrinsic phenotypic plasticity associated with specific histone methylation profiles. In addition to expanding our understanding of this potential source of β cells, this compendium of carefully generated human gene expression and epigenomic data in islet cell subtypes constitutes a truly valuable resource for the field.
Creating new β cells: cellular transmutation by genomic alchemy
Moss, Larry G.
2013-01-01
To address insulin insufficiency, diabetes research has long focused on techniques for replacing insulin-producing β cells. Studies in mice have suggested that, under some conditions, α cells possess the capacity to transdifferentiate into β cells, although the mechanisms that drive this conversion are unclear. In this issue, Bramswig et al. analyzed the methylation states of purified human α, β, and acinar cells and found α cells exhibit intrinsic phenotypic plasticity associated with specific histone methylation profiles. In addition to expanding our understanding of this potential source of β cells, this compendium of carefully generated human gene expression and epigenomic data in islet cell subtypes constitutes a truly valuable resource for the field. PMID:23434598
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sakaida, Satoshi; Shimokawa, Yohei; Asaka, Toru
2015-07-15
Highlights: • Eu{sup 3+}-doped CaZrO{sub 3}-based compounds were synthesized by the solid state reaction. • PL emission intensity at 614 nm was changed by the second dopant cations. • The site substituted by Eu{sup 3+} cations was investigated by using XRD and ALCHEMI technique. • The dominant Eu{sup 3+} substitution site was found as the B site (Zr{sup 4+}) in the CaZrO{sub {sup 3}}. • The dominant Eu{sup 3+} substitution site could be strongly influenced by the co-dopants. - Abstract: Eu{sup 3+}-doped CaZrO{sub 3}, SrZrO{sub 3}, and Mg{sup 2+}- or Sr{sup 2+}-co-doped CaZrO{sub 3} were synthesized by conventional solid statemore » reaction and their photoluminescence (PL) properties were characterized. The Eu{sup 3+}-doped CaZrO{sub 3}-based compounds exhibited characteristic emissions of Eu{sup 3+} (f–f transition). The intensity of the main PL emission peak at 614 nm increased with Mg{sup 2+} co-doping, while it decreased with the amount of co-doped Sr{sup 2+}. The site substituted by Eu{sup 3+} cations in the CaZrO{sub 3}-based compounds was investigated by X-ray diffraction analysis and energy-dispersive X-ray analysis based on the electron channeling effects in transmission electron microscopy. The Eu{sup 3+} cations were determined to occupy mainly the B site (Zr{sup 4+}) in CaZrO{sub 3}. The dominant Eu{sup 3+} substitution site was also strongly influenced by the co-dopant, and the ionic radius of the co-dopant was identified as an important factor that determines the dominant Eu{sup 3+} substitution site.« less
Rocking-beam spectrum images and ALCHEMI of Ni{sub 50}Al{sub 40}Fe{sub 10}
DOE Office of Scientific and Technical Information (OSTI.GOV)
Anderson, I.M.; Bentley, J.
1997-04-01
A rocking-beam energy-dispersive X-ray (EDX) spectrum image was acquired near the [035] zone axis of a B2-ordered alloy of composition Ni{sub 50}Al{sub 40}Fe{sub 10}. Images comparable to those acquired by Rossouw et al. were formed a posteriori by integrating the X-ray intensities in windows enclosing the Al-K, Fe-K{sub {alpha}}, and Ni-K{sub {alpha}} characteristic X-ray peaks for each pixel of the spectrum image. These images are shown along with a bright-field transmission channeling pattern (TCP), which records the signal from the bright-field STEM detector as the incident beam direction is varied with the beam-tilt coils, and an EDX spectrum from onemore » pixel of the image. The range of orientations from which the spectrum image was acquired is indicated by the square superimposed on the TCP. ALCHEMI (atom-location by channeling-enhanced microanalysis) was performed on a subset of the spectrum image using standard methods. Spectra from a series of {approximately}30 pixels along lines parallel to the (200) band were summed at each of 31 orientations relative to the band in the range 0 {le} {theta}/{theta}{sub 200} {le} 2.3. Characteristic X-ray intensities of the K-shell X-rays of Ni, Fe, and Al were extracted from the 31 summed spectra with the simplex fitting procedure of the DTSA spectral analysis software. The fraction of Fe on the `Ni`-site from this analysis, p{sub Fe`Ni`} = 23.8 {+-} 2.1%, is in excellent agreement with p{sub Fe`Ni`} = 23.7 {+-} 0.9%, which was determined by an analysis of a series of ten spectra acquired at orientations of the crystal carefully chosen so that the contributions of nonsystematic reflections are negligible.« less
The Scientific Legacy of Fred Hoyle
NASA Astrophysics Data System (ADS)
Gough, Douglas
2011-08-01
Introduction M. Rees; 1. Fred Hoyle's major work in the context of astronomy and astrophysics today W. L. W. Sargent; 2. Sir Fred Hoyle and the theory of the synthesis of the elements D. Arnett; 3. Fred Hoyle: contributions to the theory of galaxy formation G. Efstathiou; 4. Highlights of Fred Hoyle's work on interstellar matter and star formation P. M. Solomon; 5. Accretion H. Bondi; 6. From dust to life C. Wickramasinghe; 7. Worlds without end or beginning J. D. Barrow; 8. Evolutionary cosmologies - then and now M. S. Longair; 9. Alternative ideas in cosmology J. N. Narlikar; 10. Red Giants - then and now J. Faulkner; 11. Modern alchemy: Fred Hoyle and element building by neutron capture E. M. Burbidge; 12. Concluding remarks G. Burbidge.
The Scientific Legacy of Fred Hoyle
NASA Astrophysics Data System (ADS)
Gough, Douglas
2005-03-01
Introduction M. Rees; 1. Fred Hoyle's major work in the context of astronomy and astrophysics today W. L. W. Sargent; 2. Sir Fred Hoyle and the theory of the synthesis of the elements D. Arnett; 3. Fred Hoyle: contributions to the theory of galaxy formation G. Efstathiou; 4. Highlights of Fred Hoyle's work on interstellar matter and star formation P. M. Solomon; 5. Accretion H. Bondi; 6. From dust to life C. Wickramasinghe; 7. Worlds without end or beginning J. D. Barrow; 8. Evolutionary cosmologies - then and now M. S. Longair; 9. Alternative ideas in cosmology J. N. Narlikar; 10. Red Giants - then and now J. Faulkner; 11. Modern alchemy: Fred Hoyle and element building by neutron capture E. M. Burbidge; 12. Concluding remarks G. Burbidge.
Electrochemistry of Silicon: Instrumentation, Science, Materials and Applications
NASA Astrophysics Data System (ADS)
Lehmann, Volker
2002-04-01
Silicon has been and will most probably continue to be the dominant material in semiconductor technology. Although the defect-free silicon single crystal is one of the best understood systems in materails science, its electrochemistry to many people is still a kind of "alchemy". This view is partly due to the interdisciplinary aspects of the topic: Physics meets chemistry at the silicon-electrolyte interface. This book gives a comprehensive overview of this important aspect of silicon technology as well as examples of applications ranging from photonic crystals to biochips. It will serve materials scientists as well as engineers involved in silicon technology as a quick reference with its more than 150 technical tables and diagrams and ca. 1000 references cited for easy access of the original literature.
Towards a Deeper Understanding of the Nucleus with Exotic Nuclei
NASA Astrophysics Data System (ADS)
Ormand, Erich
2006-10-01
Despite more than fifty years of study, many questions about now nuclei are put together remain. While nuclei near the valley of stability have provided a wealth of information, they are not sufficient to provide us with a comprehensive and unified description of the nucleus. Especially lacking is an accurate picture of those exotic species that are the basis of cosmic alchemy. The missing pieces in the puzzle can be filled in with a determined experimental and theoretical effort focusing on nuclei lying far from the valley of stability. Here, I will outline the intellectual challenges that can be addressed by proposed exotic-beam facilities, and how new experimental data will quide and refine theoretical descriptions of the nucleus.
Rádl, S; Hafner, W; Budesínsky, M; Hejnová, L; Krejcí, I
2000-06-01
A series of epibatidine analogs and their positional isomers bearing an 8-azabicyclo[3.2.1]octane moiety is described. Also some of their simplified analogs bearing a 3-piperidine moiety are reported. Their receptor binding profiles (5-HT1A, 5-HT1B, M1, M2, neuronal nicotinic receptor) and analgesic activity (hot plate, acetic acid induced writhing) have been studied. Some of the compounds, especially those containing an 8-azabicyclo[3.2.1]oct-2-ene moiety possess high afinity for the nicotinic cholinergic receptor. The most analgesically active compounds are also highly toxic. Optimized structures (PM3-MOPAC, Alchemy 2000, Tripos Inc.) of compounds 1-9 were compared with that of epibatidine.
'The history of hindu chemistry' a critical review.
Harsha, N M; Nagaraja, T N
2010-10-01
'The History of Hindu Chemistry' is one of the rare, important books published in twentieth century. Sir Prafulla Chandra Ray, the author of this book, who was a chemist by profession, has contributed greatly to the field of Rasashastra in his own style. The book in two volumes is in English and has achieved international recognition. The work became the cause of enlightening people specially, the Westerners about Indian Alchemy which, they were till then unaware of. In a way, 'globalization' of the concepts of Rasashastra has its starting point in the works of Sir P.C.Ray. The author has touched almost every area of Rasashastra of course, from the standpoint of modern Chemistry. A critical analysis of his contributions, the narration of the contents of the book are detailed in the paper.
"To Improve upon Hints of Things": Illustrating Isaac Newton.
Schilt, Cornelis J
2016-01-01
When Isaac Newton died in 1727 he left a rich legacy in terms of draft manuscripts, encompassing a variety of topics: natural philosophy, mathematics, alchemy, theology, and chronology, as well as papers relating to his career at the Mint. One thing that immediately strikes us is the textuality of Newton's legacy: images are sparse. Regarding his scholarly endeavours we witness the same practice. Newton's extensive drafts on theology and chronology do not contain a single illustration or map. Today we have all of Newton's draft manuscripts as witnesses of his working methods, as well as access to a significant number of books from his own library. Drawing parallels between Newton's reading practices and his natural philosophical and scholarly work, this paper seeks to understand Newton's recondite writing and publishing politics.
Drob, S L
1999-05-01
Jung's use of Kabbalistic symbols and ideas as well as his personal Kabbalistic vision are critically examined. It is argued that as great as Jung's acknowledged affinity is to the Kabbalah, his unacknowledged relationship was even greater. Jung has been accused of being a contemporary Gnostic; however, the interpretations Jung placed on Gnosticism and the texts Jung referred to on alchemy were profoundly Kabbalistic, so much so that one would be more justified in calling the Jung of the Mysterium Coniunctionis and other late works a Kabbalist in contemporary guise. Although Jung, at least during the 1930s, appears to have had powerful motives that limited his receptivity to Jewish ideas, his highly ambivalent and at times reproachable attitude toward Judaism should not prevent one from appreciating the affinities between Jungian psychology and Jewish mystical thought.
Stellar alchemy. The celestial origin of atoms
NASA Astrophysics Data System (ADS)
Cassé, Michel
Why do the stars shine? What messages can we read in the light they send to us from the depths of the night? Nuclear astrophysics is a fascinating discipline, and enables connections to be made between atoms, stars, and human beings. Through modern astronomy, scientists have managed to unravel the full history of the chemical elements, and to understand how they originated and evolved into all the elements that compose our surroundings today. The transformation of metals into gold, something once dreamed of by alchemists, is a process commonly occurring in the cores of massive stars. But the most exciting revelation is the intimate connection that humanity itself has with the debris of exploded stars. This engaging account of nucleosynthesis in stars, and the associated chemical evolution of the Universe, is suitable for the general reader.
Shaping Crystal-Crystal Phase Transitions
NASA Astrophysics Data System (ADS)
Du, Xiyu; van Anders, Greg; Dshemuchadse, Julia; Glotzer, Sharon
Previous computational and experimental studies have shown self-assembled structure depends strongly on building block shape. New synthesis techniques have led to building blocks with reconfigurable shape and it has been demonstrated that building block reconfiguration can induce bulk structural reconfiguration. However, we do not understand systematically how this transition happens as a function of building block shape. Using a recently developed ``digital alchemy'' framework, we study the thermodynamics of shape-driven crystal-crystal transitions. We find examples of shape-driven bulk reconfiguration that are accompanied by first-order phase transitions, and bulk reconfiguration that occurs without any thermodynamic phase transition. Our results suggest that for well-chosen shapes and structures, there exist facile means of bulk reconfiguration, and that shape-driven bulk reconfiguration provides a viable mechanism for developing functional materials.
Atomistic Modeling of Quaternary Alloys: Ti and Cu in NiAl
NASA Technical Reports Server (NTRS)
Bozzolo, Guillermo; Mosca, Hugo O.; Wilson, Allen W.; Noebe, Ronald D.; Garces, Jorge E.
2002-01-01
The change in site preference in NiAl(Ti,Cu) alloys with concentration is examined experimentally via ALCHEMI and theoretically using the Bozzolo-Ferrante-Smith (BFS) method for alloys. Results for the site occupancy of Ti and Cu additions as a function of concentration are determined experimentally for five alloys. These results are reproduced with large-scale BFS-based Monte Carlo atomistic simulations. The original set of five alloys is extended to 25 concentrations, which are modeled by means of the BFS method for alloys, showing in more detail the compositional range over which major changes in behavior occur. A simple but powerful approach based on the definition of atomic local environments also is introduced to describe energetically the interactions between the various elements and therefore to explain the observed behavior.
Page, Christine
2008-01-01
Christine Page, MD, has been a physician and healer for more than 30 years. She received her medical degree at London University. Her medical specialties include obstetrics, gynecology, pediatrics, family practice, and homeopathy. She was raised in a family with rich spiritual traditions, and this background, in addition to her wide experience and expertise in traditional healthcare practices, enabled her to have an instrumental role in integrating complementary medicine into the British National Health Service. Dr Page is the author of 6 books: Frontiers of Health (Ebury Press; 1992); Mirror of Existence (Ebury Press; 1995); Beyond the Obvious (Ebury Press; 1998); Mind, Body, Spirit Workbook (Ebury Press; 2000); Spiritual Alchemy (Ebury Press; 2003); and the recently released 2012 and the Galactic Centre (Inner Traditions; 2008).
Alexandria, An emporium in the Silk Road, and the Traffic of Unusual Medicines.
Rosso, Ana Maria
2016-12-01
In Ancient times, an active trade of exotic and peculiar drugs tool place along the Silk Road. Coming through China, India, Central Asia, Armenia, including Colchis, Arabia, Nubia as far as Greece and Rome, it was centered during Ptolemaic and Roman times in Alexandria, the world Emporium, remarkably advanced in scientific medicine. Physicians required a variety of active ingredients for their pharmacotherapy, following various related branches of medicine. These included: 1) herbal remedies: including toxic plants 2) polypharmacy: missing together all kind of drugs 3) dreckapotheke or copropharmacy, employing unclean materials 4) organic therapy, using exotic or domestic animal products 5) aromatherapy, lined to essential oils and perfumes 6) 'medical astrology and botany', regarding the laws of sympathy in the natural world 7) alchemy and magic medicine: with occult knowledge
Thunder among the pines: defining a pan-Asian soma.
Dannaway, Frederick
2009-03-01
Many ancient cultures and religions engaged in various techniques and used various substances to instigate religious experience and to alter perception. These techniques of psycho-sexual drug yoga reached an unparalleled level of sophistication that arose and was often cloaked in practical terms of alchemy and metallurgy. The Vedic tradition describes this plant-based ritualism as soma, which has been identified by Gordon Wasson as the mushroom Amanita muscaria. This article traces these soma-influenced sects of esoteric Buddhism that exerted influences from India, China and Tibet to Japan. Some of the key components, practices and symbolism are retained despite numerous cultural filters. Japan's tradition of esoteric Buddhism can thus be seen to have preserved and incorporated the soma/amrita mushroom lore into its own traditions of mountain ascetic mystics.
Alchemy to reason: Effective use of Cumulative Effects Assessment in resource management
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hegmann, George, E-mail: george.hegmann@stantec.com; Yarranton, G.A., E-mail: yarran@shaw.ca
2011-09-15
Cumulative Effects Assessment (CEA) is a tool that can be useful in making decisions about natural resource management and allocation. The decisions to be made include those (i) necessary to construct planning and regulatory frameworks to control development activity so that societal goals will be achieved and (ii) whether or not to approve individual development projects, with or without conditions. The evolution of CEA into a more successful tool cannot occur independently of the evolution of decision making processes. Currently progress is painfully slow on both fronts. This paper explores some opportunities to accelerate improvements in decision making in naturalmore » resource management and in the utility of CEA as a tool to assist in making such decisions. The focus of the paper is on how to define the public interest by determining what is acceptable.« less
The structural and electronic properties of amorphous HgCdTe from first-principles calculations
NASA Astrophysics Data System (ADS)
Zhao, Huxian; Chen, Xiaoshuang; Lu, Jianping; Shu, Haibo; Lu, Wei
2014-01-01
Amorphous mercury cadmium telluride (a-MCT) model structures, with x being 0.125 and 0.25, are obtained from first-principles calculations. We generate initial structures by computation alchemy method. It is found that most atoms in the network of amorphous structures tend to be fourfold and form tetrahedral structures, implying that the chemical ordered continuous random network with some coordination defects is the ideal structure for a-MCT. The electronic structure is also concerned. The gap is found to be 0.30 and 0.26 eV for a-Hg0.875Cd0.125Te and a-Hg0.75Cd0.25Te model structures, independent of the composition. By comparing with the properties of crystalline MCT with the same composition, we observe a blue-shift of energy band gap. The localization of tail states and its atomic origin are also discussed.
[Federik Grisogono and alchemistry].
Pausek-Bazdar, Snjezana
2011-01-01
Frederico Grisogono's 1958 collection of essays De modo collegiandi, prognosticandi et curandi febres: necnon de humana felicitate ac denique de fluxu et refluxu maris presents his views on alchemy. He acknowledges the traditional association between the sky and earth and the correlation between the seven planets and seven earthly metals. He attempted to empirically determine the position and the properties of these planets (the Sun and the Moon were also considered planets at the time). He clearly distinguished the good and the bad planets and those that agree (love) or disagree (hate) with one another. However, Grisogono abandons the traditional Renaissance viewpoint on planet position inasmuch as he claims that Venus (copper) and Jupiter (tin) need to change places. He discards alchemist practical teaching that base metals can be turned into noble metals such as gold and silver. His argument against it is based on then generally adopted sulphur-mercury metal structure theory.
Markov state models and molecular alchemy
NASA Astrophysics Data System (ADS)
Schütte, Christof; Nielsen, Adam; Weber, Marcus
2015-01-01
In recent years, Markov state models (MSMs) have attracted a considerable amount of attention with regard to modelling conformation changes and associated function of biomolecular systems. They have been used successfully, e.g. for peptides including time-resolved spectroscopic experiments, protein function and protein folding , DNA and RNA, and ligand-receptor interaction in drug design and more complicated multivalent scenarios. In this article, a novel reweighting scheme is introduced that allows to construct an MSM for certain molecular system out of an MSM for a similar system. This permits studying how molecular properties on long timescales differ between similar molecular systems without performing full molecular dynamics simulations for each system under consideration. The performance of the reweighting scheme is illustrated for simple test cases, including one where the main wells of the respective energy landscapes are located differently and an alchemical transformation of butane to pentane where the dimension of the state space is changed.
Alchemy or Science? Compromising Archaeology in the Deep Sea
NASA Astrophysics Data System (ADS)
Adams, Jonathan
2007-06-01
In the torrid debate between archaeology and treasure hunting, compromise is often suggested as the pragmatic solution, especially for archaeology carried out either in deep water or beyond the constraints that commonly regulate such activities in territorial seas. Both the wisdom and the need for such compromise have even been advocated by some archaeologists, particularly in forums such as the internet and conferences. This paper argues that such a compromise is impossible, not in order to fuel confrontation but simply because of the nature of any academic discipline. We can define what archaeology is in terms of its aims, theories, methods and ethics, so combining it with an activity founded on opposing principles must transform it into something else. The way forward for archaeology in the deep sea does not lie in a contradictory realignment of archaeology’s goals but in collaborative research designed to mesh with emerging national and regional research and management plans.
NASA Astrophysics Data System (ADS)
Safouhi, Hassan; Hoggan, Philip
2003-01-01
This review on molecular integrals for large electronic systems (MILES) places the problem of analytical integration over exponential-type orbitals (ETOs) in a historical context. After reference to the pioneering work, particularly by Barnett, Shavitt and Yoshimine, it focuses on recent progress towards rapid and accurate analytic solutions of MILES over ETOs. Software such as the hydrogenlike wavefunction package Alchemy by Yoshimine and collaborators is described. The review focuses on convergence acceleration of these highly oscillatory integrals and in particular it highlights suitable nonlinear transformations. Work by Levin and Sidi is described and applied to MILES. A step by step description of progress in the use of nonlinear transformation methods to obtain efficient codes is provided. The recent approach developed by Safouhi is also presented. The current state of the art in this field is summarized to show that ab initio analytical work over ETOs is now a viable option.
Properties of amorphous GaN from first-principles simulations
NASA Astrophysics Data System (ADS)
Cai, B.; Drabold, D. A.
2011-08-01
Amorphous GaN (a-GaN) models are obtained from first-principles simulations. We compare four a-GaN models generated by “melt-and-quench” and the computer alchemy method. We find that most atoms tend to be fourfold, and a chemically ordered continuous random network is the ideal structure for a-GaN albeit with some coordination defects. Where the electronic structure is concerned, the gap is predicted to be less than 1.0 eV, underestimated as usual by a density functional calculation. We observe a highly localized valence tail and a remarkably delocalized exponential conduction tail in all models generated. Based upon these results, we speculate on potential differences in n- and p-type doping. The structural origin of tail and defect states is discussed. The vibrational density of states and dielectric function are computed and seem consistent with experiment.
Veronesi, Umberto; Martinón-Torres, Marcos
2018-06-18
Glass distillation equipment from an early modern alchemical laboratory was analyzed for its technology of manufacture and potential origin. Chemical data show that the assemblage can be divided into sodium-rich, colorless distillation vessels made with glass from Venice or its European imitation, and potassium-rich dark-brown non-specialized forms produced within the technological tradition of forest glass typical for central and north-western Europe. These results complete our understanding of the supply of technical apparatus at one of the best-preserved alchemical laboratories and highlight an early awareness of the need for high-quality instruments to guarantee the successful outcome of specialized chemical operations. This study demonstrates the potential of archaeological science to inform historical research around the practice of early chemistry and the development of modern science. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
The Radium Terrors. Science Fiction and Radioactivity before the Bomb.
Candela, Andrea
2015-01-01
At the beginning of the 20th century the collective imagination was fascinated and terrified by the discovery of radium. A scientific imagery sprang up around radioactivity and was disseminated by public lectures and newspaper articles discussing the ambiguous power of this strange substance. It was claimed that radium could be used to treat cholera, typhus and tuberculosis, but at the same time there were warnings that it could be used for military purposes. The media and the scientists themselves employed a rich vocabulary influenced by religion, alchemy and magic. The ambivalent power of radioactive elements exerted a great influence on science fiction novelists. This paper will examine some significant works published in Europe, America and Russia during the first decades of the 20th century and their role in the creation of the complex imagery of radioactivity that seized the public imagination long before the invention of the atomic bomb.
Supervising the uncanny: the play within the play.
Leader, Carol
2015-11-01
The writer offers a combined experience in analysis and the performing arts to explore uncanny aspects of the unconscious subtext of the patient's inner drama; subtext which can remain hidden from view in supervision. Freud and Jung's understanding of uncanny experience is considered together with a painting from medieval alchemy and Matte Blanco's conceptions concerning the symmetrical nature of unconscious process. Theatre and the work of the theatre director and actor in approaching the multidimensional aspects of a play are then introduced. Finally clinical case material from group supervision demonstrates how the 'theatre of therapy' and the work of the supervisory couple and group promote the emergence of a more authentic conscious asymmetrical response to the patient's 'script' that can break the 'spell' of the transference/countertransference relationship. This in turn brings meaning to the underlying and implicit 'stage directions' that the patient has been unconsciously communicating. © 2015, The Society of Analytical Psychology.
Ab initio investigation of the structural and electronic properties of amorphous HgTe.
Zhao, Huxian; Chen, Xiaoshuang; Lu, Jianping; Shu, Haibo; Lu, Wei
2014-01-29
We present the structure and electronic properties of amorphous mercury telluride obtained from first-principle calculations. The initial configuration of amorphous mercury telluride is created by computation alchemy. According to different exchange–correlation functions in our calculations, we establish two 256-atom models. The topology of both models is analyzed in terms of radial and bond angle distributions. It is found that both the Te and the Hg atoms tend to be fourfold, but with a wrong bond rate of about 10%. The fraction of threefold and fivefold atoms also shows that there are a significant number of dangling and floating bonds in our models. The electronic properties are also obtained. It is indicated that there is a bandgap in amorphous HgTe, in contrast to the zero bandgap for crystalline HgTe. The structures of the band tail and defect states are also discussed.
Life is hard: countering definitional pessimism concerning the definition of life
NASA Astrophysics Data System (ADS)
Smith, Kelly C.
2016-10-01
Cleland and Chyba published a classic piece in 2002 that began a movement I call definitional pessimism, where it is argued that there is no point in attempting anything like a general definition of life. This paper offers a critical response to the pessimist position in general and the influential arguments offered by Cleland and her collaborators in particular. One such argument is that all definitions of life fall short of an ideal in which necessary and sufficient conditions produce unambiguous categorizations that dispose of all counterexamples. But this concept of definition is controversial within philosophy; a fact that greatly diminishes the force of the admonition that biologists should conform to such an ideal. Moreover, biology may well be fundamentally different from logic and the physical sciences from which this ideal is drawn, to the point where definitional conformity misrepresents biological reality. Another idea often pushed is that the prospects for definitional success concerning life are on a par with medieval alchemy's attempts to define matter - that is, doomed to fail for lack of a unifying scientific theory. But this comparison to alchemy is both historically inaccurate and unfair. Planetary science before the discovery of the first exoplanets offers a much better analogy, with much more optimistic conclusions. The pessimists also make much of the desirability of using microbes as models for any universal concept of life, from which they conclude that certain types of 'Darwinian' evolutionary definitions are inadequate. But this argument posits an unrealistic ideal, as no account of life can both be universal and do justice to the sorts of precise causal mechanisms microbes exemplify. The character of biology and the demand for universality in definitions of life thus probably accords better with functional rather than structural categories. The bottom line is that there is simply no viable alternative, either pragmatically or theoretically, to the pursuit of definitions. If nothing else, the empirical data the pessimists demand will be a very long time coming and scientists will of necessity continue to employ definitions of life in the interim. Chastising them for this will only drive their ideas underground where they can escape critical analysis, making the problems caused by problematic conceptions of life worse.
[Alchemy, freemasonry and homeopathy].
Pinet, Patrice
2011-07-01
In this article we are showing that homeopathic doctrine has really esoteric and occult origins as it was suspected by a few authors, nevertheless we saw Hahnemann also using scientific writers. As early as twenty-two years old Hahnemann was initiate in the freemasonry, very in vogue at that time. He will be life long attached to it and will keep close to distinguished freemasons. Freemasonry has conveid enlightement philosophical ideas as well as occult, alchemical and theosophical ones by successive incursion of very different orders. Among these we can find a few rosicrucians orders. At the beginning of 17th century in Germany, the first rosicrucians authors appealed to Paracelse, and the first members of their legendary fraternity manifested their contempt for the practice of transmutation into gold and must devote themselves to gratuitous medical practice (famous utopia). Freemasonry took again these philanthropic views so that Hahnemann was certainly involved to the ideas of Paracelse and his followers through the Rosicrucians which played a substantial part within freemasonry before homeopathy rose.
Surface and Thin Film Analysis during Metal Organic Vapour Phase Epitaxial Growth
NASA Astrophysics Data System (ADS)
Richter, Wolfgang
2007-06-01
In-situ analysis of epitaxial growth is the essential ingredient in order to understand the growth process, to optimize growth and last but not least to monitor or even control the epitaxial growth on a microscopic scale. In MBE (molecular beam epitaxy) in-situ analysis tools existed right from the beginning because this technique developed from Surface Science technology with all its electron based analysis tools (LEED, RHEED, PES etc). Vapour Phase Epitaxy, in contrast, remained for a long time in an empirical stage ("alchemy") because only post growth characterisations like photoluminescence, Hall effect and electrical conductivity were available. Within the last two decades, however, optical techniques were developed which provide similar capabilities as in MBE for Vapour Phase growth. I will discuss in this paper the potential of Reflectance Anisotropy Spectroscopy (RAS) and Spectroscopic Ellipsometry (SE) for the growth of thin epitaxial semiconductor layers with zincblende (GaAs etc) and wurtzite structure (GaN etc). Other techniques and materials will be also mentioned.
Williams, Antony J.; Peck, Lou; Ekins, Sean
2017-01-01
There is an abundance of free online tools accessible to scientists and others that can be used for online networking, data sharing and measuring research impact. Despite this, few scientists know how these tools can be used or fail to take advantage of using them as an integrated pipeline to raise awareness of their research outputs. In this article, the authors describe their experiences with these tools and how they can make best use of them to make their scientific research generally more accessible, extending its reach beyond their own direct networks, and communicating their ideas to new audiences. These efforts have the potential to drive science by sparking new collaborations and interdisciplinary research projects that may lead to future publications, funding and commercial opportunities. The intent of this article is to: describe some of these freely accessible networking tools and affiliated products; demonstrate from our own experiences how they can be utilized effectively; and, inspire their adoption by new users for the benefit of science. PMID:28928951
A case of cellular alchemy: lineage reprogramming and its potential in regenerative medicine
Asuelime, Grace E.; Shi, Yanhong
2012-01-01
The field of regenerative medicine is rapidly gaining momentum as an increasing number of reports emerge concerning the induced conversions observed in cellular fate reprogramming. While in recent years, much attention has been focused on the conversion of fate-committed somatic cells to an embryonic-like or pluripotent state, there are still many limitations associated with the applications of induced pluripotent stem cell reprogramming, including relatively low reprogramming efficiency, the times required for the reprogramming event to take place, the epigenetic instability, and the tumorigenicity associated with the pluripotent state. On the other hand, lineage reprogramming involves the conversion from one mature cell type to another without undergoing conversion to an unstable intermediate. It provides an alternative approach in regenerative medicine that has a relatively lower risk of tumorigenesis and increased efficiency within specific cellular contexts. While lineage reprogramming provides exciting potential, there is still much to be assessed before this technology is ready to be applied in a clinical setting. PMID:22371436
Lorenz Oken and Naturphilosophie in Jena, Paris and London.
Breidbach, Olaf; Ghiselin, Michael T
2002-01-01
Although Lorenz Oken is a classic example of Naturphilosophie as applied to biology, his views have been imperfectly understood. He is best viewed as a follower of Schelling who consistently attempted to apply Schelling's ideas to biological data. His version of Naturphilosophic, however, was strongly influenced by older pseudoscience traditions, especially alchemy and numerology as they had been presented by Robert Fludd, whose works were current in Jena and available to him. According to those influences, parts of Oken's philosophical conception were communicable even in a non-idealistic scientific culture, for example in Paris, where Oken met Etienne Geoffroy Saint-Hilaire. Geoffroy however was embedded in a French intellectual tradition, and the correspondence between his views and those of Oken was only superficial. The English anatomist Richard Owen attempted to incorporate the views of Oken and Geoffroy within his own, idiosyncratic system. Although Darwin knew of Oken's ideas, it was Geoffroy who really affected his evolutionary biology, and any influence of Oken must have been attenuated to the point of triviality.
Dannaway, Frederick R
2010-12-01
This paper seeks to emphasize what may be the most primary mode of altering consciousness in the ancient world: namely, the burning of substances for inhalation in enclosed areas. While there is abundant literature on archaic uses of entheogenic plants, the literature on psychoactive incenses is quite deficient. From the tents of nomadic tribes to the small meditation rooms of Taoist adepts, the smoldering fumes of plants and resins have been used to invoke and banish and for shamanic travels since humanity mastered fire. The text provides details of primary "incense cults" while highlighting some commonalities and shared influences when possible. Further speculation suggests that selective burning of certain substances, such as mercury and sulphur, may have contributed to their lasting use and veneration in alchemy from India and China to the Arabian and European protochemists. This article would have a companion online database for images and further examples of ingredients in various incenses from China to ancient Greece.
Genetic aspects of population policy.
Morton, N E
1999-08-01
Every science begins in folklore and matures as it reacts against dogma and myth. Astronomy developed in the Neolithic, but it did not outgrow astrology until the sixteenth century. Chemistry discarded alchemy at about the same time. On the contrary, the short history of genetics has been concurrent with the pseudo-science of eugenics, which, at times, has been widely accepted and incorporated in population policy and directive genetic counselling, with rare opposition by geneticists. Societal pressures are likely to increase with the power of genetic technology, the fear it generates and the perception that population growth threatens human welfare. Without a pertinent ethical code, geneticists are vulnerable to both temptation and opprobrium. The intrusion of eugenics into genetic counselling has been a recent source of concern to societies and congresses of genetics. This review traces the causes of this concern and the manner of its expression in the absence of an international voice for genetics that could address ethical and other common interests.
Prinke, Rafat T
2014-01-01
The translation of Chymiaphilosophica by Jakub Barner is the second publication in Polish historiography of a printed source work on early modem chemistry (alchemy) written by a Polish citizen, well known and influencial across Europe (the first such translation comprised the treatises of Michael Sendivogius). This admirable initiative of unquestionable value to Polish historians of science resulted in an elegantly published volume, with an extensive introduction and useful appendices. The language of the translation is pleasant to read, retaining the spirit of the original by means of a moderate use of archaisms and generally accurate selection of proper terminology. A closer comparison of some fragments of the translation reveals, however, that it omits essential words, phrases and even entire sentences. The translation itself is occasionally incorrect as well, completely changing the meaning of the author's text and distorting his intentions, thereby undermining the reliability of the Polish translation as a whole. In the factual layer, identifying both chemical substances and (especially) the names of the authors cited by Barner often appear to be doubtful or problematic. Apart from numerous obvious mistakes, as well as leaving many surnames unidentified even when it was very difficult, the translators and/or editors of the Polish text created some non-existent authors as a result of errors produced while copying their surnames from the original text or due to unfounded assumptions that some chemical or botanical terms are names of chemical authors. There is also no consistency in the spelling of surnames (usually left in the Latin form, sometimes spelled with wrong inflection, but also modernised). In the biographical introduction there are also numerous factual errors and some bizarre mistranslations. Not only did its author fail to correct invalid information of earlier biographers of Barner, relying only on the most obvious and accessible publications, but also perpetuated these "historiographical myths" and even created new ones. Neither did he consult any sources apart from some other of Barners published books. Writing from the positivist perspective and on the basis of outdated literature, he also sustained the categorical distinction between alchemy and chemistry, already rejected in contemporary historiography, thus presenting the role and position of Barner in the history of science not quite adequately. If one adds to that the very numerous "typos" throughout the book, it may be regarded as a negative example of poor source editing in almost every respect, even though it makes a pleasant reading.
Synthetic Biology: Applications in the Food Sector.
Tyagi, Ashish; Kumar, Ashwani; Aparna, S V; Mallappa, Rashmi H; Grover, Sunita; Batish, Virender Kumar
2016-08-17
Synthetic biology also termed as "genomic alchemy" represents a powerful area of science that is based on the convergence of biological sciences with systems engineering. It has been fittingly described as "moving from reading the genetic code to writing it" as it focuses on building, modeling, designing and fabricating novel biological systems using customized gene components that result in artificially created genetic circuitry. The scientifically compelling idea of the technological manipulation of life has been advocated since long time. Realization of this idea has gained momentum with development of high speed automation and the falling cost of gene sequencing and synthesis following the completion of the human genome project. Synthetic biology will certainly be instrumental in shaping the development of varying areas ranging from biomedicine, biopharmaceuticals, chemical production, food and dairy quality monitoring, packaging, and storage of food and dairy products, bioremediation and bioenergy production, etc. However, potential dangers of using synthetic life forms have to be acknowledged and adoption of policies by the scientific community to ensure safe practice while making important advancements in the ever expanding field of synthetic biology is to be fully supported and implemented.
NASA Astrophysics Data System (ADS)
Blyth, Alison
2016-04-01
Speleothems are well used archives for chemical records of terrestrial environmental change, and the integration of records from a range of isotopic, inorganic, and organic geochemical techniques offers significant power in reconstructing both changes in past climates and identifying the resultant response in the overlying terrestrial ecosystems. The use of organic geochemistry in this field offers the opportunity to recover new records of vegetation change (via biomarkers and compound specific isotopes), temperature change (via analysis of glycerol dialkyl glycerol tetraethers, a compound group derived from microbes and varying in structure in response to temperature and pH), and changes in soil microbial behaviour (via combined carbon isotope analysis). However, to date the use of organic geochemical techniques has been relatively limited, due to issues relating to sample size, concerns about contamination, and unanswered questions about the origins of the preserved organic matter and rates of transport. Here I will briefly review recent progress in the field, and present a framework for the future research needed to establish organic geochemical analysis in speleothems as a robust palaeo-proxy approach.
Designing superhard metals: The case of low borides
NASA Astrophysics Data System (ADS)
Liang, Yongcheng; Qin, Ping; Jiang, Haitao; Zhang, Lizhen; Zhang, Jing; Tang, Chun
2018-04-01
The search for new superhard materials has usually focused on strong covalent solids. It is, however, a huge challenge to design superhard metals because of the low resistance of metallic bonds against the formation and movement of dislocations. Here, we report a microscopic mechanism of enhancing hardness by identifying highly stable thermodynamic phases and strengthening weak slip planes. Using the well-known transition-metal borides as prototypes, we demonstrate that several low borides possess unexpectedly high hardness whereas high borides exhibit an anomalous hardness reduction. Such an unusual phenomenon originates from the peculiar bonding mechanisms in these compounds. Furthermore, the low borides have close compositions, similar structures, and degenerate formation energies. This enables facile synthesis of a multiphase material that includes a large number of interfaces among different borides, and these interfaces form nanoscale interlocks that strongly suppress the glide dislocations within the metal bilayers, thereby drastically enhancing extrinsic hardness and achieving true superhard metals. Therefore, this study not only elucidates the unique mechanism responsible for the anomalous hardening in this class of borides but also offers a valid alchemy to design novel superhard metals with multiple functionalities.
NASA Astrophysics Data System (ADS)
Liao, Yang; Lin, Jintian; Cheng, Ya
2013-12-01
Recently, hybrid integration of multifunctional micro-components for creating complex, intelligent micro/nano systems has attracted significant attention. These micro-/nano-systems have important applications in a variety of areas, such as healthcare, environment, communication, national security, and so on. However, fabrication of micro/nano systems incorporated with different functions is still a challenging task, which generally requires fabrication of discrete microcomponents beforehand followed by assembly and packaging procedures. Furthermore, current micro-/nano-fabrication techniques are mainly based on the well-established planar lithographic approach, which suffer from severe issues in producing three dimensional (3D) structures with complex geometries and arbitrary configurations. In recent years, the rapid development of femtosecond laser machining technology has enabled 3D direct fabrication and integration of multifunctional components, such as microfluidics, microoptics, micromechanics, microelectronics, etc., into single substrates. In this invited talk, we present our recent progress in this active area. Particularly, we focus on fabrication of 3D micro- and nanofluidic devices and 3D high-Q microcavities in glass substrates by femtosecond laser direct writing.
[Illustrations of of alchemy vessels in a manuscript of Pseudo-Geber].
Kurzmann, Peter
2011-01-01
Manuscript ric. 933 "Geber de investigatione perfectionis magisterii", kept in the Libreria Riccardiana in Florence, is a 13th century Latin version of the "Book of the Secret of the Secrets" ("kitab sirr al-asrar") by the Arabian alchemist al-Razi (865-925). The manuscript shows on page 25r a series of drawings of alchemistic vessels and apparatus which do not figure in the Arabian original but which are of particular interest as they date from as early as the 13th century and are numbered amongst the earliest drawings of this kind which we possess. The publication of the manuscript by Julius Ruska in 1935 shows only copied drawings with his interpretations of the legends. There was considerable interest in the publication of the original page 25r and in the course of further study it became clear that these interpretations had to be revised. These new interpretations presented in detail in this paper are justified and put into an alchemistic context. In some cases they give a new understanding and differ considerably from Ruska's versions.
Hiding in plain sight: Jung, astrology, and the psychology of the unconscious.
Buck, Stephanie
2018-04-01
Astrology was a lifelong interest for C.G. Jung and an important aid in his formulation of psyche and psychic process. Archetypally configured, astrology provided Jung an objective means to a fuller understanding of the analysand's true nature and unique individuation journey. Jung credits astrology with helping to unlock the mystery of alchemy and in so doing providing the symbol language necessary for deciphering the historically remote cosmology of Gnosticism. Astrology also aided Jung's work on synchronicity. Despite astrology's worth to Jung's development of analytical psychology, its fundamental role in guiding his discoveries is all but absent from historical notice. The astrological natal chart seems rarely used clinically, and many clinicians seem unaware of its value as a dynamic diagram of the personality and the potentialities within which nature and nurture foster and/or discourage for individual growth and development over the lifespan. This paper charts Jung's interest in astrology and suggests why his great regard for it and other paranormal or occult practices remains largely neglected and unknown. © 2018, The Society of Analytical Psychology.
Institute on oil and gas law and taxation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ernst, A.C.
1979-01-01
This volume contains discussions, by acknowledged authorities, of important legal and tax problems of the oil and gas industries. The articles were delivered in condensed form as lectures during the Thirtieth Annual Institute on Oil and Gas Law and Taxation held by the Southwest Legal Foundation. The following topics are discussed: crude oil issues; natural gas liquid-selected problems in regulation; recent developments in DOE audits of refiners and marketers; contrasting administrative procedures before the DOE, DOE organization - the limit of regulatory power, current major developments in federal natural gas legislation and regulation; dedication and abandonment - problems under sectionmore » 7(b) of the Natural Gas Act; Natural gas pipelines - their regulation and their current problems, current antitrust developments in oil and gas exploration and production; developments in nonregulatory oil and gas law; recent developments in oil and gas taxation; entity selection - an experience in alchemy - a comparison of corporations, partnerships, and joint ventures; foreign money and US oil and gas - tax considerations; 1978 legislative developments in oil and gas taxation; and recapture of intangibles under section 1254. (DC)« less
Zhu, Caifang Jeremy
2009-09-01
This paper provides a historical, religious-philosophical context for the study of the Daoist text known as The Secret of the Golden Flower. An updated study is conducted into the controversy over the source of the text including the editions translated by Richard Wilhelm and Thomas Cleary. The main teachings of the text and the basics of two major denominations of Daoism are introduced to ground later critiques of Jung's commentary. The psychodynamics of analytical psychology, especially those concerned with integration of unconscious contents and the realization of the self (individuation) are compared with the psycho-spiritual dynamics of integration in Eastern spirituality based on the Golden Flower text. The paper concludes that it was amiss for Jung to have equated the Western 'unconscious' with states of higher consciousness in Eastern meditation practices, although his claim that Eastern higher consciousness is characterized by a nebulous state of non-intentionality does raise questions about the appropriateness of calling Eastern meditative states 'consciousness'. A new concept is required to characterize the special qualities of this psychic state shared generally by Eastern spiritual traditions and a more meaningful comparison may be found in Jung's concept of the self.
Modern alchemy: Fred Hoyle and element building by neutron capture
NASA Astrophysics Data System (ADS)
Burbidge, E. Margaret
Fred Hoyle's fundamental work on building the chemical elements by nuclear processes in stars at various stages in their lives began with the building of elements around iron in the very dense hot interiors of stars. Later, in the paper by Burbidge, Burbidge, Fowler and Hoyle, we four showed that Hoyle's "equilibrium process" is one of eight processes required to make all of the isotopes of all the elements detected in the Sun and stars. Neutron capture reactions, which Fred had not considered in his epochal 1946 paper, but for which experimental data were just becoming available in 1957, are very important, in addition to the energy-generating reactions involving hydrogen, helium, carbon, nitrogen and oxygen, for building all of the elements. They are now providing clues to the late stages of stellar evolution and the earliest history of our Galaxy. I describe here our earliest observational work on neutron capture processes in evolved stars, some new work on stars showing the results of the neutron capture reactions, and data relating to processes ending in the production of lead, and I discuss where this fits into the history of stars in our own Galaxy.
Cao, Xiaodong; MacNaughton, Piers; Deng, Zhengyi; Yin, Jie; Zhang, Xi; Allen, Joseph G
2018-02-02
Twitter provides a rich database of spatiotemporal information about users who broadcast their real-time opinions, sentiment, and activities. In this paper, we sought to investigate the holistic influence of land use and time period on public sentiment. A total of 880,937 tweets posted by 26,060 active users were collected across Massachusetts (MA), USA, through 31 November 2012 to 3 June 2013. The IBM Watson Alchemy API (application program interface) was employed to quantify the sentiment scores conveyed by tweets on a large scale. Then we statistically analyzed the sentiment scores across different spaces and times. A multivariate linear mixed-effects model was used to quantify the fixed effects of land use and the time period on the variations in sentiment scores, considering the clustering effect of users. The results exposed clear spatiotemporal patterns of users' sentiment. Higher sentiment scores were mainly observed in the commercial and public areas, during the noon/evening and on weekends. Our findings suggest that social media outputs can be used to better understand the spatial and temporal patterns of public happiness and well-being in cities and regions.
López-Valdés, Julio César
2018-01-01
Mary Wollstonecraft Godwin, better known as Mary Shelley, and her romantic vision of the world gave life to an endless progeny of literacy stories; also originated the myth of the mortal creator who generate life from science. Unexpectedly the history has been considered as a myth, due to acts grounded in facts of certain “truthful;” such were galvanism and the study of the electrical potential in living beings by the two Italian physicians: Luigi Galvani and Giovanni Aldini. Also, is possible to proclaim direct influence on the work by the European folklore surrounding the theologian, alchemist Johann Konrad Dippel and physician who habited the Frankenstein’s Castle from his birth, and further developing the “life elixir.” The similarities between the novel and the life of the three historical figures suggests that Mary Shelley, belonging to a socially graceful and educated class, was aware of the scientific dispute over the understanding of electricity. Shelley’s creative world, full of gothic and romantic hues, shows direct influence of alchemy speaking of the “spark of life” as well as works published by Galvani and Aldini. Copyright: © 2018 SecretarÍa de Salud.
Transforming Matter: A History of Chemistry from Alchemy to the Buckyball by Trevor H. Levere
NASA Astrophysics Data System (ADS)
Truman Schwartz, A.
2001-08-01
By and large, the chemistry is presented in a logical and comprehensible form. People and ideas are emphasized. However, because of Transforming Matter's brevity and its intended audience, there are inevitable oversimplifications and sins of omission. There were also a few sins of commission in the uncorrected proof that I read. On page 159 there is an implication that equilibrium does not exist in "irreversible" processes such as the precipitation of silver chloride. The author rushes through electron orbitals in one paragraph (page 178) in which he mistakenly refers to something he calls "Planck's equation" and appears to identify p orbitals with n = 2. On the next page we are told that "overlapping p orbitals produced a pi bond." True, but they can also produce a sigma bond. And on page 198 we learn that "a single Freon molecule can cause the decomposition of millions of ozone molecules." The most frequently cited estimate is 100,000 ozone molecules decomposed per Freon molecule. This may be the nit picking of a physical chemist, but it does reflect some of the hazards of trying to achieve an admirable goal--introducing readers to the fascinating history of our fascinating science.
John Dee and the alchemists: Practising and promoting English alchemy in the Holy Roman Empire
Rampling, Jennifer M.
2012-01-01
This paper investigates John Dee’s relationship with two kinds of alchemist: the authorities whose works he read, and the contemporary practitioners with whom he exchanged texts and ideas. Both strands coincide in the reception of works attributed to the famous English alchemist, George Ripley (d. c. 1490). Dee’s keen interest in Ripley appears from the number of transcriptions he made of ‘Ripleian’ writings, including the Bosome book, a manuscript discovered in 1574 and believed to have been written in Ripley’s own hand. In 1583, Dee and his associate Edward Kelley left England for East Central Europe, taking with them a proportion of Dee’s vast library, including alchemical books—the contents of which would soon pique the interest of continental practitioners. Kelley used Ripley’s works, including the Bosome book, not only as sources of practical information, but as a means of furthering his own relationships with colleagues and patrons: transactions that in turn influenced Ripley’s posthumous continental reception. The resulting circulation of texts allows us to trace, with unusual precision, the spread of English alchemical ideas in the Holy Roman Empire from the late sixteenth century.
MacNaughton, Piers; Deng, Zhengyi; Yin, Jie; Zhang, Xi; Allen, Joseph G.
2018-01-01
Twitter provides a rich database of spatiotemporal information about users who broadcast their real-time opinions, sentiment, and activities. In this paper, we sought to investigate the holistic influence of land use and time period on public sentiment. A total of 880,937 tweets posted by 26,060 active users were collected across Massachusetts (MA), USA, through 31 November 2012 to 3 June 2013. The IBM Watson Alchemy API (application program interface) was employed to quantify the sentiment scores conveyed by tweets on a large scale. Then we statistically analyzed the sentiment scores across different spaces and times. A multivariate linear mixed-effects model was used to quantify the fixed effects of land use and the time period on the variations in sentiment scores, considering the clustering effect of users. The results exposed clear spatiotemporal patterns of users’ sentiment. Higher sentiment scores were mainly observed in the commercial and public areas, during the noon/evening and on weekends. Our findings suggest that social media outputs can be used to better understand the spatial and temporal patterns of public happiness and well-being in cities and regions. PMID:29393869
Mining Tacitus: secrets of empire, nature and art in the reason of state.
Keller, Vera
2012-06-01
A new political practice, the 'reason of state', informed the ends and practices of natural study in the late sixteenth century. Informed by the study of the Roman historian Tacitus, political writers gathered 'secrets of empire' from both history and travel. Following the economic reorientation of 'reason of state' by Giovanni Botero (1544-1617), such secrets came to include bodies of useful particulars concerning nature and art collected by an expanding personnel of intelligencers. A comparison between various writers describing wide-scale collections, such as Botero, Francis Bacon (1561-1626), Jakob Bornitz (1560-1625) and Matthias Bernegger (1582-1640), reveals that seventeenth-century natural intelligencers across Europe not only were analogous to political intelligencers, but also were sometimes one and the same. Those seeking political prudence cast themselves as miners, prying precious particulars from the recesses of history, experience and disparate disciplines, including mathematics, alchemy and natural philosophy. The seventeenth-century practice of combining searches for secrets of empire, nature and art contests a frequent historiographical divide between empirical science and Tacitism or reason of state. It also points to the ways political cunning shaped the management of information for both politics and the study of nature and art.
Some reflections on the influence of Chinese thought on Jung and his psychological theory.
Stein, Murray
2005-04-01
Jung claimed that Richard Wilhelm, whose masterful translations of Chinese wisdom literature into a European language (German) and thence into Western consciousness have brought Chinese modes of thinking to so many, was one of the most important influences on his own life and work. The contacts between the two men, which took place from the early 1920's until Wilhelm's death in 1930, were few but intense and for Jung decisive in several ways. Wilhelm's translations of the I Ching and The Secret of the Golden Flower opened new avenues for Jung that had far-reaching consequences on his research and writing after 1930. The latter opened the door to the study of alchemy as a key to the archetypal process of individuation as rooted in the collective unconscious. 'Synchronicity' is a term that grew out of his contact with Chinese thought, in particular with the I Ching. From his contact with Chinese thought, additionally, he received confirmation of the view, independently arrived at, that adult psychological development is not linear but rather circular and spiral-like. The letters between Jung and Wilhelm illuminate the great importance Jung ascribed to Wilhelm's contribution toward bridging East and West and the potential value of Chinese philosophy for psychotherapy.
Yan, Shanzhao
2002-06-01
The emergency treatments for the damage and bleeding of the vagina, and the sharp pubic pain of young virgins which were caused occurred by the sexual art, were recorded in traditional medicine books, such as the "Ji yan fang" and others. It is a fact that in ancient China some people used the sexual art of having intercourse with several young virgins at the same time in order to increase their health and keep perpetual youth and longevity. The famous traditional general-medical book, "qian jin yao fang" recommended that method to rich persons too. It is supposed that the beginning of the sexual art of having intercourse with several young virgins traces back to the times of Emperor Hanwu , but it seems to have disappeared from the historical stage in the Song period. On the other hand, the criticisms from the traditional medicine books and the secret languages of internal alchemy used for the Taoist sacred books show that the sexual art of having intercourse with several young virgins was still going on behind the scene in the Ming and Qing periods. Even if we consider the historical changes of ethics and mortality, we now cannot but criticize this behavior of abusing juveniles for the sexual art.
Art, archetypes and alchemy: images of self following treatment for breast cancer.
Thibeault, Catherine; Sabo, Brenda M
2012-04-01
The loss or alteration of a breast poses a threat to a woman's selfhood, particularly those aspects that embrace feminine identity such as sexuality and caring. The use of art as a vehicle for recreating a sense of self after breast cancer surgery framed the study that generated the stories reported here. A team of nurse-researchers and professional artists entered into a collaborative partnership aimed at creating life-like prototypes of the torsos of two breast cancer survivors. The authors sought to understand participants' experiences of healing through the narratives of their breast cancer journeys and their experiences of creating art through the use of their bodies. The participants consented to having interviews and casting sessions audio-taped. The authors used thematic analysis to explore the narratives. The authors present excerpts of stories and comment on how participants articulated the feminine archetype in the form of the Greek goddesses Hestia, Artemis, and Aphrodite. The authors explore the transformative nature of participants' experiences. The emergence of the goddess archetypes in participants' narratives was an unanticipated result of the study. The authors invite readers to contemplate these anecdotes and embark on their own quest for deeper knowledge of breast cancer experiences. Copyright © 2011 Elsevier Ltd. All rights reserved.
High-pressure alchemy on a small-pore zeolite
NASA Astrophysics Data System (ADS)
Lee, Y.
2011-12-01
While an ever-expanding variety of zeolites with a wide range of framework topology is available, it is desirable to have a way to tailor the chemistry of the zeolitic nanopores for a given framework topology via controlling both the coordination-inclusion chemistry and framework distortion/relaxation. This is, however, subjected to the ability of a zeolitic nanopore to allow the redistribution of cations-water assembly and/or insertion of foreign molecules into the pores and channels. Small-pore zeolites such as natrolite (Na16Al16Si24O80x16H2O), however, have been known to show very limited capacity for any changes in the confinement chemistry. We have recently shown that various cation-exchanged natrolites can be prepared under modest conditions from natural sodium natrolite and exhibit cation-dependent volume expansions by up to 18.5% via converting the elliptical channels into progressively circular ones. Here, we show that pressure can be used as a unique and clean tool to further manipulate the chemistry of the natrolite nanopores. Our recent crystallographic and spectroscopic studies of pressure-insertion of foreign molecules, trivalent-cation exchange under pressure, and pressure-induced inversion of cation-water coordination and pore geometry in various cation-exchanged natrolites will be presented.
Variable Emittance Electrochromic Devices for Satellite Thermal Control
NASA Astrophysics Data System (ADS)
Demiryont, Hulya; Shannon, Kenneth C.
2007-01-01
An all-solid-state electrochromic device (ECD) was designed for electronic variable emissivity (VE) control. In this paper, a low weight (5g/m2) electrochromic thermal control device, the EclipseVEECD™, is detailed as a viable thermal control system for spacecraft outer surface temperatures. Discussion includes the technology's performance, satellite applications, and preparations for space based testing. This EclipseVEECD™ system comprises substrate/mirror electrode/active element/IR transparent electrode layers. This system tunes and modulates reflection/emittance from 5 μm to 15 μm region. Average reflectance/emittance modulation of the system from the 400 K to 250 K region is about 75%, while at room temperature (9.5 micron) reflectance/emittance is around 90%. Activation voltage of the EclipseVEECD™ is around ±1 Volt. The EclipseVEECD™ can be used as a smart thermal modulator for the thermal control of satellites and spacecraft by monitoring and adjusting the amount of energy emitted from the outer surfaces. The functionality of the EclipseVEECD™ was successfully demonstrated in vacuum using a multi-purpose heat dissipation/absorption test module, the EclipseHEAT™. The EclipseHEAT™ has been successfully flight checked and integrated onto the United States Naval Alchemy MidSTAR satellite, scheduled to launch December 2006.
Primordial alchemy: from the Big Bang to the present universe
NASA Astrophysics Data System (ADS)
Steigman, Gary
Of the light nuclides observed in the universe today, D, 3He, 4He, and 7Li are relics from its early evolution. The primordial abundances of these relics, produced via Big Bang Nucleosynthesis (BBN) during the first half hour of the evolution of the universe provide a unique window on Physics and Cosmology at redshifts ~1010. Comparing the BBN-predicted abundances with those inferred from observational data tests the consistency of the standard cosmological model over ten orders of magnitude in redshift, constrains the baryon and other particle content of the universe, and probes both Physics and Cosmology beyond the current standard models. These lectures are intended to introduce students, both of theory and observation, to those aspects of the evolution of the universe relevant to the production and evolution of the light nuclides from the Big Bang to the present. The current observational data is reviewed and compared with the BBN predictions and the implications for cosmology (e.g., universal baryon density) and particle physics (e.g., relativistic energy density) are discussed. While this comparison reveals the stunning success of the standard model(s), there are currently some challenge which leave open the door for more theoretical and observational work with potential implications for astronomy, cosmology, and particle physics.
2018-01-01
The “long-life elixir” has long represented for humans a dream, a vanity's sin for remaining young and to long survive. Today, because of ageing population phenomenon, the research of antiageing interventions appears to be more important than ever, for preserving health in old age and retarding/or delaying the onset of age-related diseases. A hope is given by experimental data, which evidence the possibility of retarding ageing in animal models. In addition, it has been also demonstrated in animal life-extending studies not only the possibility of increasing longevity but also the ability to retard the onset of age-related diseases. Interestingly, this recent evidence is leading to promise of obtaining the same effects in humans and resulting in benefits for their health in old ages. In order to achieve this goal, different approaches have been used ranging from pharmacological targeting of ageing, basic biological assays, and big data analysis to the recent use of young blood, stem cells, cellular, genetic, and epigenetic reprogramming, or other techniques of regenerative medicine. However, only a little fraction of these approaches has the features for being tested in clinical applications. Here, new emerging molecules, drugs, and procedures will be described, by evidencing potential benefits and limitations. PMID:29576745
Synthesis meets theory: Past, present and future of rational chemistry
NASA Astrophysics Data System (ADS)
Fianchini, Mauro
2017-11-01
Chemical synthesis has its roots in the empirical approach of alchemy. Nonetheless, the birth of the scientific method, the technical and technological advances (exploiting revolutionary discoveries in physics) and the improved management and sharing of growing databases greatly contributed to the evolution of chemistry from an esoteric ground into a mature scientific discipline during these last 400 years. Furthermore, thanks to the evolution of computational resources, platforms and media in the last 40 years, theoretical chemistry has added to the puzzle the final missing tile in the process of "rationalizing" chemistry. The use of mathematical models of chemical properties, behaviors and reactivities is nowadays ubiquitous in literature. Theoretical chemistry has been successful in the difficult task of complementing and explaining synthetic results and providing rigorous insights when these are otherwise unattainable by experiment. The first part of this review walks the reader through a concise historical overview on the evolution of the "model" in chemistry. Salient milestones have been highlighted and briefly discussed. The second part focuses more on the general description of recent state-of-the-art computational techniques currently used worldwide by chemists to produce synergistic models between theory and experiment. Each section is complemented by key-examples taken from the literature that illustrate the application of the technique discussed therein.
Stem cell therapy for cardiovascular disease: the demise of alchemy and rise of pharmacology.
Jadczyk, T; Faulkner, A; Madeddu, P
2013-05-01
Regenerative medicine holds great promise as a way of addressing the limitations of current treatments of ischaemic disease. In preclinical models, transplantation of different types of stem cells or progenitor cells results in improved recovery from ischaemia. Furthermore, experimental studies indicate that cell therapy influences a spectrum of processes, including neovascularization and cardiomyogenesis as well as inflammation, apoptosis and interstitial fibrosis. Thus, distinct strategies might be required for specific regenerative needs. Nonetheless, clinical studies have so far investigated a relatively small number of options, focusing mainly on the use of bone marrow-derived cells. Rapid clinical translation resulted in a number of small clinical trials that do not have sufficient power to address the therapeutic potential of the new approach. Moreover, full exploitation has been hindered so far by the absence of a solid theoretical framework and inadequate development plans. This article reviews the current knowledge on cell therapy and proposes a model theory for interpretation of experimental and clinical outcomes from a pharmacological perspective. Eventually, with an increased association between cell therapy and traditional pharmacotherapy, we will soon need to adopt a unified theory for understanding how the two practices additively interact for a patient's benefit. © 2012 The Authors. British Journal of Pharmacology © 2012 The British Pharmacological Society.
Kahn, Didier
2010-11-01
This article provides a preliminary description of medieval and early modern alchemical poetry composed in Latin and in the principal vernacular languages of western Europe. It aims to distinguish the various genres in which this poetry flourished, and to identify the most representative aspects of each cultural epoch by considering the medieval and early modern periods in turn. Such a distinction (always somewhat artificial) between two broad historical periods may be justified by the appearance of new cultural phenomena that profoundly modified the character of early modern alchemical poetry: the ever-increasing importance of the prisca theologia, the alchemical interpretation of ancient mythology, and the rise of neo-Latin humanist poetry. Although early modern alchemy was marked by the appearance of new doctrines (notably the alchemical spiritus mundi and Paracelsianism), alchemical poetry was only superficially modified by criteria of a scientific nature, which therefore appear to be of lesser importance. This study falls into two parts. Part I provides a descriptive survey of extant poetry, and in Part II the results of the survey are analysed in order to highlight such distinctive features as the function of alchemical poetry, the influence of the book market on its evolution, its doctrinal content, and the question of whether any theory of alchemical poetry ever emerged. Part II is accompanied by an index of the authors and works cited in both parts.
Kahn, Didier
2011-03-01
This article provides a preliminary description of medieval and early modern alchemical poetry composed in Latin and in the principal vernacular languages of western Europe. It aims to distinguish the various genres in which this poetry flourished, and to identify the most representative aspects of each cultural epoch by considering the medieval and early modern periods in turn. Such a distinction (always somewhat artificial) between two broad historical periods may be justified by the appearance of new cultural phenomena that profoundly modified the character of early modern alchemical poetry: the ever-increasing importance of the prisca theologia, the alchemical interpretation of ancient mythology, and the rise of neo-Latin humanist poetry. Although early modern alchemy was marked by the appearance of new doctrines (notably the alchemical spiritus mundi and Paracelsianism), alchemical poetry was only superficially modified by criteria of a scientific nature, which therefore appear to be of lesser importance. This study falls into two parts. Part I provides a descriptive survey of extant poetry, and in Part II the results of the survey are analysed in order to highlight such distinctive features as the function of alchemical poetry, the influence of the book market on its evolution, its doctrinal content, and the question of whether any theory of alchemical poetry ever emerged. Part II is accompanied by an index of the authors and works cited in both parts.
Electron capture in collisions of Al2+ ions with He atoms at intermediate energies
NASA Astrophysics Data System (ADS)
Watanabe, A.; Sato, H.; Gu, J. P.; Hirsch, G.; Buenker, R. J.; Kimura, M.
2001-09-01
Electron capture resulting from collisions of Al2+ ions with He atoms from 0.15 to 1000 keV/u is investigated using a molecular-orbital representation within a semiclassical frame. Molecular electronic states and corresponding couplings are determined by the ALCHEMY program. Sixteen molecular states all connecting to single-electron-capture processes are included, and hence radial and rotational couplings among these channels are fully considered. The trajectory effect arising from the straight-line, Coulomb, and ground-state potential trajectories for electron-capture and excitation processes is carefully assessed. The electron-capture cross section by ground-state Al2+(2S) ions slowly increases before it reaches a maximum of 1.3×10-16 cm2 at 100 keV/u. Those for metastable Al2+(2P) ions sharply increase with increasing energy, and reach a peak at 1 keV/u with a value of 1.5×10-16 cm2. The earlier experimental data are found to be larger by an order of magnitude although their energy dependence is in good accord with the present result. Excitation cross sections for both the ground and metastable states are found to be much larger by a factor of 2-3 than corresponding capture cross sections above 1 keV/u although they become comparable below this energy.
Egger-Biniores, Deborah
2007-04-01
Training in Zurich has its own special character but also is marked by the very fact that it is in Zurich. Zurich radiates its own distinct energy and carries a specific historical significance in the world of analytical psychology. This, like all things with psychic energy, has a spectrum of meaning. This spectrum, as well as the 'spirit' of the place, will be critically examined, taking into account the 'blessings' and 'curses' of such genius loci. Training in Zurich is experientially based and is first and foremost an initiation: an initiation into symbolic life, or rather life where symbol plays an important role. Training is understood to involve a transformation of one's self, much like the 8th century alchemist Morienus Romanus understood the opus as a 'human transformation system'. It is not merely an education. The requirement of 'immersion' is core to the experience of becoming an analyst in Zurich and this sets up a valuable discomfort between rational intellectual learning and intuitive experience, between knowing and not-knowing. How does this dis-serve the making of an analyst? What is implicit in this immersion and its discomfort? Does it have a role in today's emphasis on clinical and empirical training? Does Zurich still offer something unique and valuable in the world of training, or is it passé? From these questions, the dichotomy of what is 'urgent' and 'essential' in training will be examined.
Compression selective solid-state chemistry
NASA Astrophysics Data System (ADS)
Hu, Anguang
Compression selective solid-state chemistry refers to mechanically induced selective reactions of solids under thermomechanical extreme conditions. Advanced quantum solid-state chemistry simulations, based on density functional theory with localized basis functions, were performed to provide a remarkable insight into bonding pathways of high-pressure chemical reactions in all agreement with experiments. These pathways clearly demonstrate reaction mechanisms in unprecedented structural details, showing not only the chemical identity of reactive intermediates but also how atoms move along the reaction coordinate associated with a specific vibrational mode, directed by induced chemical stress occurred during bond breaking and forming. It indicates that chemical bonds in solids can break and form precisely under compression as we wish. This can be realized through strongly coupling of mechanical work to an initiation vibrational mode when all other modes can be suppressed under compression, resulting in ultrafast reactions to take place isothermally in a few femtoseconds. Thermodynamically, such reactions correspond to an entropy minimum process on an isotherm where the compression can force thermal expansion coefficient equal to zero. Combining a significantly brief reaction process with specific mode selectivity, both statistical laws and quantum uncertainty principle can be bypassed to precisely break chemical bonds, establishing fundamental principles of compression selective solid-state chemistry. Naturally this leads to understand the ''alchemy'' to purify, grow, and perfect certain materials such as emerging novel disruptive energetics.
Seeing in the dark - I. Multi-epoch alchemy
NASA Astrophysics Data System (ADS)
Huff, Eric M.; Hirata, Christopher M.; Mandelbaum, Rachel; Schlegel, David; Seljak, Uroš; Lupton, Robert H.
2014-05-01
Weak lensing by large-scale structure is an invaluable cosmological tool given that most of the energy density of the concordance cosmology is invisible. Several large ground-based imaging surveys will attempt to measure this effect over the coming decade, but reliable control of the spurious lensing signal introduced by atmospheric turbulence and telescope optics remains a challenging problem. We address this challenge with a demonstration that point spread function (PSF) effects on measured galaxy shapes in the Sloan Digital Sky Survey (SDSS) can be corrected with existing analysis techniques. In this work, we co-add existing SDSS imaging on the equatorial stripe in order to build a data set with the statistical power to measure cosmic shear, while using a rounding kernel method to null out the effects of the anisotropic PSF. We build a galaxy catalogue from the combined imaging, characterize its photometric properties and show that the spurious shear remaining in this catalogue after the PSF correction is negligible compared to the expected cosmic shear signal. We identify a new source of systematic error in the shear-shear autocorrelations arising from selection biases related to masking. Finally, we discuss the circumstances in which this method is expected to be useful for upcoming ground-based surveys that have lensing as one of the science goals, and identify the systematic errors that can reduce its efficacy.
Priesner, Claus
2011-01-01
Germany's Hausväterliteratur, the "literature of the fathers of the houses," was once a popular genre but today is seldom studied. Roughly, this literature, as its name suggests, comprises books on the proper keeping of noble households and mansions. Interestingly, besides the content which one might expect in such books, the organization of personnel, the arrangement of festivities, discussions of the various branches of technical skills, economic advice and the whole field of agriculture, fishing and hunting, these books also contain remarkably large amounts of information directly connected with magic and an associated popular medicine (Volksmedizin). This medicine involved treatment administered mostly by laywomen instead of regular physicians and was based not just upon traditional medical knowledge per se but also upon magical practices. Also found in such texts are alchemical ideas and recipes. This means that despite the fact that such books were written and published in the 17th and early 18th century, the Age of Enlightenment, conceptions found in them are still deeply rooted in older intellectual currents, in Medieval and Renaissance thinking. The present study examines examples of alchemical, magical and popular medical ideas in three such works and seeks to explain how pre-enlightenment ideas and thought could maintain such an influential place in the intellectual world of a later time dominated by other philosophies.
The Oxford Guide to the History of Physics and Astronomy
NASA Astrophysics Data System (ADS)
Heilbron, John L.
2005-06-01
With over 150 alphabetically arranged entries about key scientists, concepts, discoveries, technological innovations, and learned institutions, the Oxford Guide to Physics and Astronomy traces the history of physics and astronomy from the Renaissance to the present. For students, teachers, historians, scientists, and readers of popular science books such as Galileo's Daughter , this guide deciphers the methods and philosophies of physics and astronomy as well as the historical periods from which they emerged. Meant to serve the lay reader and the professional alike, this book can be turned to for the answer to how scientists learned to measure the speed of light, or consulted for neat, careful summaries of topics as complicated as quantum field theory and as vast as the universe. The entries, each written by a noted scholar and edited by J. L. Heilbron, Professor of History and Vice Chancellor, Emeritus, University of California, Berkeley, reflect the most up-to-date research and discuss the applications of the scientific disciplines to the wider world of religion, law, war, art and literature. No other source on these two branches of science is as informative or as inviting. Thoroughly cross-referenced and accented by dozens of black and white illustrations, the Oxford Guide to Physics and Astronomy is the source to turn to for anyone looking for a quick explanation of alchemy, x-rays and any type of matter or energy in between.
Hunt, Harry T
2012-02-01
A needed rapprochement between Jung and the contemporary human sciences may rest less on the much debated relevance of a biologistic collective unconscious than on a re-inscribing of an archetypal imagination, as the phenomenological and empirical core of Jungian psychology. The most promising approaches in this regard in terms of theory and research in psychology come from combining the cognitive psychology of metaphor and synaesthesia, individual differences in imaginative absorption and openness to numinous experience and spirituality as a form of symbolic intelligence. On the socio-cultural side, this cognitive psychology of archetypal imagination is also congruent with Lévi-Strauss on the metaphoric roots of mythological thinking, and Durkheim on a sociology of collective consciousness. This conjoined perspective, while validating the cross cultural commonality of physical metaphor intuited by Jung and Hillman on alchemy, also shows Jung's Red Book, considered as the expressive source for his more formal psychology, to be far closer in spirit to a socio-cultural collective consciousness, based on metaphoric imagination, than to a phylogenetic or evolutionary unconscious. A mutual re-inscribing of Jung into congruent areas of contemporary psychology, anthropology, sociology, and vice versa, can help to further validate Jung's key observations and is fully consistent with Jung's own early efforts at synthesis within the human sciences. © 2012, The Society of Analytical Psychology.
Changing Dielectrics into Multiferroics---Alchemy Enabled by Strain
NASA Astrophysics Data System (ADS)
Schlom, Darrell
2011-03-01
Ferroelectric ferromagnets are exceedingly rare, fundamentally interesting multiferroic materials. The properties of what few compounds simultaneously exhibit these phenomena pale in comparison to useful ferroelectrics or ferromagnets: their spontaneous polarizations (Ps) or magnetizations (Ms) are smaller by a factor of 1000 or more. The same holds for (magnetic or electric) field-induced multiferroics. Recently, however, Fennie and Rabe proposed a new route to ferroelectric ferromagnets---transforming magnetically ordered insulators that are neither ferroelectric nor ferromagnetic, of which there are many, into ferroelectric ferromagnets using a single control parameter: strain. The system targeted, EuTi O3 , was predicted to simultaneously exhibit strong ferromagnetism (Ms ~ ~ ~7~μB /Eu) and strong ferroelectricity (Ps ~ ~ ~10~ μ C/cm2) under large biaxial compressive strain. These values are orders of magnitude higher than any known ferroelectric ferromagnet and rival the best materials that are solely ferroelectric or ferromagnetic. Hindered by the absence of an appropriate substrate to provide the desired compression, we show 3 both experimentally and theoretically the emergence of a multiferroic state under biaxial tension with the unexpected benefit that even lower misfits are required, thereby enabling higher quality crystalline films. The resulting genesis of a strong ferromagnetic ferroelectric points the way to high temperature manifestations of this spin-phonon coupling mechanism. Our work demonstrates that a single experimental parameter, strain, simultaneously controls multiple order parameters and is a viable alternative tuning parameter to composition for creating multiferroics. C.J. Fennie and K.M. Rabe, Phys. Rev. Lett. 97 (2006) 267602.
Stellar Explosions: Hydrodynamics and Nucleosynthesis
NASA Astrophysics Data System (ADS)
Jose, Jordi
2016-01-01
Stars are the main factories of element production in the universe through a suite of complex and intertwined physical processes. Such stellar alchemy is driven by multiple nuclear interactions that through eons have transformed the pristine, metal-poor ashes leftover by the Big Bang into a cosmos with 100 distinct chemical species. The products of stellar nucleosynthesis frequently get mixed inside stars by convective transport or through hydrodynamic instabilities, and a fraction of them is eventually ejected into the interstellar medium, thus polluting the cosmos with gas and dust. The study of the physics of the stars and their role as nucleosynthesis factories owes much to cross-fertilization of different, somehow disconnected fields, ranging from observational astronomy, computational astrophysics, and cosmochemistry to experimental and theoretical nuclear physics. Few books have simultaneously addressed the multidisciplinary nature of this field in an engaging way suitable for students and young scientists. Providing the required multidisciplinary background in a coherent way has been the driving force for Stellar Explosions: Hydrodynamics and Nucleosynthesis. Written by a specialist in stellar astrophysics, this book presents a rigorous but accessible treatment of the physics of stellar explosions from a multidisciplinary perspective at the crossroads of computational astrophysics, observational astronomy, cosmochemistry, and nuclear physics. Basic concepts from all these different fields are applied to the study of classical and recurrent novae, type I and II supernovae, X-ray bursts and superbursts, and stellar mergers. The book shows how a multidisciplinary approach has been instrumental in our understanding of nucleosynthesis in stars, particularly during explosive events.
Stellar Explosions: Hydrodynamics and Nucleosynthesis
NASA Astrophysics Data System (ADS)
José, Jordi
2015-12-01
Stars are the main factories of element production in the universe through a suite of complex and intertwined physical processes. Such stellar alchemy is driven by multiple nuclear interactions that through eons have transformed the pristine, metal-poor ashes leftover by the Big Bang into a cosmos with 100 distinct chemical species. The products of stellar nucleosynthesis frequently get mixed inside stars by convective transport or through hydrodynamic instabilities, and a fraction of them is eventually ejected into the interstellar medium, thus polluting the cosmos with gas and dust. The study of the physics of the stars and their role as nucleosynthesis factories owes much to cross-fertilization of different, somehow disconnected fields, ranging from observational astronomy, computational astrophysics, and cosmochemistry to experimental and theoretical nuclear physics. Few books have simultaneously addressed the multidisciplinary nature of this field in an engaging way suitable for students and young scientists. Providing the required multidisciplinary background in a coherent way has been the driving force for Stellar Explosions: Hydrodynamics and Nucleosynthesis. Written by a specialist in stellar astrophysics, this book presents a rigorous but accessible treatment of the physics of stellar explosions from a multidisciplinary perspective at the crossroads of computational astrophysics, observational astronomy, cosmochemistry, and nuclear physics. Basic concepts from all these different fields are applied to the study of classical and recurrent novae, type I and II supernovae, X-ray bursts and superbursts, and stellar mergers. The book shows how a multidisciplinary approach has been instrumental in our understanding of nucleosynthesis in stars, particularly during explosive events.
Stem cell therapy for cardiovascular disease: the demise of alchemy and rise of pharmacology
Jadczyk, T; Faulkner, A; Madeddu, P
2013-01-01
Regenerative medicine holds great promise as a way of addressing the limitations of current treatments of ischaemic disease. In preclinical models, transplantation of different types of stem cells or progenitor cells results in improved recovery from ischaemia. Furthermore, experimental studies indicate that cell therapy influences a spectrum of processes, including neovascularization and cardiomyogenesis as well as inflammation, apoptosis and interstitial fibrosis. Thus, distinct strategies might be required for specific regenerative needs. Nonetheless, clinical studies have so far investigated a relatively small number of options, focusing mainly on the use of bone marrow-derived cells. Rapid clinical translation resulted in a number of small clinical trials that do not have sufficient power to address the therapeutic potential of the new approach. Moreover, full exploitation has been hindered so far by the absence of a solid theoretical framework and inadequate development plans. This article reviews the current knowledge on cell therapy and proposes a model theory for interpretation of experimental and clinical outcomes from a pharmacological perspective. Eventually, with an increased association between cell therapy and traditional pharmacotherapy, we will soon need to adopt a unified theory for understanding how the two practices additively interact for a patient's benefit. LINKED ARTICLES This article is part of a themed section on Regenerative Medicine and Pharmacology: A Look to the Future. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2013.169.issue-2 PMID:22712727
The late medieval kidney--nephrology in and about the fourteenth century.
Eknoyan, Garabed
2012-01-01
The Late Medieval Period was a decisive period in the history of medicine. It was then that medical education was integrated into the universities that were coming into existence and when medicine made its transition from a menial trade to a regulated profession with a statutory basis of learning and graduation. It was also then that the necessities of understanding the fabric of the body was realized; for the first time in history, the study of anatomy and of human dissection were incorporated into the medical curriculum. This was a defining change whose subsequent expansion and evolution would bring about the study of function (physiology) and changes in disease (pathology). Few advances were made in the study of the kidney, which was considered part of the venous circulation, whose function was subservient to that of nutrition in eliminating excess fluid. Uroscopy flourished and reached unrealistic levels of dominance in the diagnosis, treatment, and prognostication of any and all diseases, especially in the hands of quacks and charlatans. Alchemy, a mysterious pseudo-science, blossomed into a discipline that nurtured experimentation and laid the rudimentary foundations of scientific study, chemistry, and pharmacology. It was also then that surgery took form as a specialty that actually provided much of the medical care of the period including that of the principal diseases of the kidney, obstruction and calculi, and thereby laid the foundations of what in time would become urology. © 2012 Wiley Periodicals, Inc.
Fallen star legends and traditional religion of Japan: an aspect of star lore
NASA Astrophysics Data System (ADS)
Goto, Akira
2015-08-01
Japanese star lore is a complex mixture of animism, Buddhism, Shinto-ism, Confucianism and folk beliefs. Although some studies have been done on rituals concerning constellation developed in esoteric Buddhism (e.g. Journal Culture and Cosmos, Vol. 10 no 1 and 2), studies on other aspects of Japanese star lore are limited, in particular, to the English audience.In historic literatures, there often mentioned abnormal astronomical phenomena, such as, eclipse, meteors and comets. In this paper, I will discuss the possibility of reference to these astronomical phenomena in order to talk about some historical facts.In western part of Japan, there are Shinto shrines and Buddhistic temples that are said to be built as monuments of fallen stars. Usually fallen stars were divided into three, and a trio of shrines/temples are said to be the remnants of this phenomenon. Similar legends are found in Kudamatsu (that means "fallen pine=pine where stars fallen") of Yamaguchi Prefecture, Bisei-cho (that means "beautiful star") of Okayama Prefecture, Hoshida (that means "rice field or village of star") shrine of Osaka, and also Hoshida shrine of Nagoya.The purpose of this presentation is not to argue whether fallen star legend was truly astronomical phenomenon, such as, meteor or not. Instead, I will discuss why similar legends have been talked concerning the origin of particular shrines or temples. Citing Eliade who related gorge and alchemy producing spark to astronomical phenomena, I will disclose the possibility to relate these astronomical legends to the coming of the naturalized Japanese from Korean Peninsula who introducd forge to Japan abound 5 to 6 centuries.
Boosters and barriers for direct cardiac reprogramming.
Talkhabi, Mahmood; Zonooz, Elmira Rezaei; Baharvand, Hossein
2017-06-01
Heart disease is currently the most significant cause of morbidity and mortality worldwide, which accounts for approximately 33% of all deaths. Recently, a promising and alchemy-like strategy has been developed called direct cardiac reprogramming, which directly converts somatic cells such as fibroblasts to cardiac lineage cells such as cardiomyocytes (CMs), termed induced CMs or iCMs. The first in vitro cardiac reprogramming study, mediated by cardiac transcription factors (TFs)-Gata4, Tbx5 and Mef2C-, was not enough efficient to produce an adequate number of fully reprogrammed, functional iCMs. As a result, numerous combinations of cardiac TFs exist for direct cardiac reprogramming of mouse and human fibroblasts. However, the efficiency of direct cardiac reprogramming remains low. Recently, a number of cellular and molecular mechanisms have been identified to increase the efficiency of direct cardiac reprogramming and the quality of iCMs. For example, microgrooved substrate, cardiogenic growth factors [VEGF, FGF, BMP4 and Activin A], and an appropriate stoichiometry of TFs boost the direct cardiac reprogramming. On the other hand, serum, TGFβ signaling, activators of epithelial to mesenchymal transition, and some epigenetic factors (Bmi1 and Ezh2) are barriers for direct cardiac reprogramming. Manipulating these mechanisms by the application of boosters and removing barriers can increase the efficiency of direct cardiac reprogramming and possibly make iCMs reliable for cell-based therapy or other potential applications. In this review, we summarize the latest trends in cardiac TF- or miRNA-based direct cardiac reprogramming and comprehensively discuses all molecular and cellular boosters and barriers affecting direct cardiac reprogramming. Copyright © 2017 Elsevier Inc. All rights reserved.
Those astronomers crazy about the skies, or the story of the observation of double stars
NASA Astrophysics Data System (ADS)
Ling, J. F.
2015-05-01
Those astronomers crazy about the skies are people who have dedicated their lives, often their fortunes, to the research and study of double stars, enigmatic star systems that like to play hide and seek while dancing a mysterious waltz. Many efforts have been made to collect the wonderful golden harvest that celestial fields provide. Starting with Sir William Herschel, organist and brilliant astronomer who documented their orbital motions, the Struve clan who undertook the first census, the Anglican priest who discovered authentic celestial jewels and all the way to current international research teams using the greatest telescopes, they all searched with the same passion. They all went beyond the mere spectacle of the eternity of these pairs, seeking the Philosopher's Stone, the secret of stellar alchemy and the means to break down the wall that imprisons our knowledge. This book is the Spanish translation of the original French text written by Paul Couteau, one of the foremost authorities on the subject. No one better than him to immerse us into the knowledge of these objects, both scientifically and historically. Despite the 25 years since its publication, the text has not lost relevance. The story never dies and the attraction that still elicits has been one of the reasons to provide readers with this Spanish translation. In addition, we have included a chapter written by Josefina F. Ling. This version, published by the Department of Publications and Scientific Communications at the University of Santiago de Compostela and partially funded by the Spanish Society of Astronomy, has an initial print of 500 copies.
NASA Astrophysics Data System (ADS)
de la Roja, J. M.; Baonza, V. G.; San Andrés, M.
2007-12-01
Verdigris is an historical pigment of synthetic origin widely used in the artistic scope, from the antiquity to beginning of 19th century. It is a greenish or green-bluish colored product resulting from corrosion of pure copper and alloys caused by the action of different chemical reagents. The preparation recipes are numerous and appear in old texts, such as: treatises of art and texts of alchemy, as well as in books of secrets, natural history and those concerning medicines. A comparative study of these recipes shows significant differences depending on the initial components and the methodology applied in the synthesis of the pigment. Consequently, typical verdigris pigments very likely correspond to a variety of chemical compositions and, in addition, it might contain certain amounts of unknown by-products. To confirm such hypothesis, four different preparation recipes of verdigris have been carefully reproduced in our laboratory, and characterized by Raman microscopy. Our experiments allowed us to establish interesting differences among the studied samples. Some differences are mostly related to the ingredients used in the elaboration of the so-called raw verdigris. In other cases, the observed variations are consequence of the recrystallization treatment of the pigment. In general, all spectra reveal the existence of common component, namely, the copper(II) acetate (hydrated or anhydrous). However, other minority components have been detected in our samples, for instance, copper oxides, copper chlorides, and ammonic salts. In some cases, these compounds allow us to deduce the type of recipe used in the elaboration of the pigment.
NASA Astrophysics Data System (ADS)
Reines, Frederick; Cowan, Clyde L.
EACH new discovery of natural science broadens our knowledge and deepens our understanding of the physical universe; but at times these advances raise new and even more fundamental questions than those which they answer. Such was the case with the discovery and investigation of the radioactive process termed `beta decay'. In this process an atomic nucleus spontaneously emits either a negative or positive electron, and in so doing it becomes a different element with the same mass number but with a nuclear charge different from that of the parent element, by one electronic charge. As might be expected, intensive investigation of this interesting alchemy of Nature has shed much light on problems concerning the atomic nucleus. A new question arose at the beginning, however, when it was found that accompanying beta decay there was an unaccountable loss of energy from the decaying nucleus1, and that one could do nothing to the apparatus in which the decay occurred to trap this lost energy2. One possible explanation was that the conservation laws (upon which the entire structure of modern science is built) were not valid when applied to regions of subatomic dimensions. Another novel explanation, but one which would maintain the integrity of the conservation laws, was a proposal by Wolfgang Pauli in 1933 which hypothesized a new and fundamental particle3 to account for the loss of energy from the nucleus. This particle would be emitted by the nucleus simultaneously with the electron, would carry with it no electric charge but, would carry the missing energy and momentum—escaping from the laboratory equipment without detection…
Archetypal-Imaging and Mirror-Gazing
Caputo, Giovanni B.
2013-01-01
Mirrors have been studied by cognitive psychology in order to understand self-recognition, self-identity, and self-consciousness. Moreover, the relevance of mirrors in spirituality, magic and arts may also suggest that mirrors can be symbols of unconscious contents. Carl G. Jung investigated mirrors in relation to the unconscious, particularly in Psychology and Alchemy. However, the relationship between the conscious behavior in front of a mirror and the unconscious meaning of mirrors has not been clarified. Recently, empirical research found that gazing at one’s own face in the mirror for a few minutes, at a low illumination level, produces the perception of bodily dysmorphic illusions of strange-faces. Healthy observers usually describe huge distortions of their own faces, monstrous beings, prototypical faces, faces of relatives and deceased, and faces of animals. In the psychiatric population, some schizophrenics show a dramatic increase of strange-face illusions. They can also describe the perception of multiple-others that fill the mirror surface surrounding their strange-face. Schizophrenics are usually convinced that strange-face illusions are truly real and identify themselves with strange-face illusions, diversely from healthy individuals who never identify with them. On the contrary, most patients with major depression do not perceive strange-face illusions, or they perceive very faint changes of their immobile faces in the mirror, like death statues. Strange-face illusions may be the psychodynamic projection of the subject’s unconscious archetypal contents into the mirror image. Therefore, strange-face illusions might provide both an ecological setting and an experimental technique for “imaging of the unconscious”. Future researches have been proposed. PMID:25379264
Archetypal-imaging and mirror-gazing.
Caputo, Giovanni B
2014-03-01
Mirrors have been studied by cognitive psychology in order to understand self-recognition, self-identity, and self-consciousness. Moreover, the relevance of mirrors in spirituality, magic and arts may also suggest that mirrors can be symbols of unconscious contents. Carl G. Jung investigated mirrors in relation to the unconscious, particularly in Psychology and Alchemy. However, the relationship between the conscious behavior in front of a mirror and the unconscious meaning of mirrors has not been clarified. Recently, empirical research found that gazing at one's own face in the mirror for a few minutes, at a low illumination level, produces the perception of bodily dysmorphic illusions of strange-faces. Healthy observers usually describe huge distortions of their own faces, monstrous beings, prototypical faces, faces of relatives and deceased, and faces of animals. In the psychiatric population, some schizophrenics show a dramatic increase of strange-face illusions. They can also describe the perception of multiple-others that fill the mirror surface surrounding their strange-face. Schizophrenics are usually convinced that strange-face illusions are truly real and identify themselves with strange-face illusions, diversely from healthy individuals who never identify with them. On the contrary, most patients with major depression do not perceive strange-face illusions, or they perceive very faint changes of their immobile faces in the mirror, like death statues. Strange-face illusions may be the psychodynamic projection of the subject's unconscious archetypal contents into the mirror image. Therefore, strange-face illusions might provide both an ecological setting and an experimental technique for "imaging of the unconscious". Future researches have been proposed.
Choo, Jae-Uk
2014-12-01
As the sciences advanced rapidly in the modern European world, outstanding achievements have been made in medicine, chemistry, biology, physiology, physics and others, which have been co-influencing each of the scientific disciplines. Accordingly, such medical and scientific phenomena began to be reflected in novels. In particular, Mary Shelley's Frankenstein includes the diverse aspects of the change and development in the medicine and science. Associated with medical and scientific information reflected in Frankenstein and Frankenstein's experiments in the text, accordingly, this research will investigate the aspects of medical and scientific development taking place in the nineteenth century in three ways. First, the medical and scientific development of the nineteenth century has been reviewed by summerizing both the information of alchemy in which Frankenstein shows his interest and the new science in general that M. Waldman introduces in the text. Second, the actual features of medical and scientific development have been examined through some examples of the experimental methods that M. Waldman implicitly uttered to Frankenstein. Third, it has been checked how the medical and scientific development is related to the main issues of mechanism and vitalism which can be explained as principles of life. Even though this research deals with the developmental process of medicine & science and origin & principles of life implied in Mary Shelley's Frankenstein, its significance is that it is the interdisciplinary research focussing on how deeply medical and scientific discourse of Mary Shelley's period has been imbedded in the nineteenth century novel.
NASA Astrophysics Data System (ADS)
Hudspeth, W. B.; Sanchez-Silva, R.; Cavner, J. A.
2010-12-01
New Mexico's Environmental Public Health Tracking System (EPHTS), funded by the Centers for Disease Control (CDC) Environmental Public Health Tracking Network (EPHTN), aims to improve health awareness and services by linking health effects data with levels and frequency of environmental exposure. As a public health decision-support system, EPHTS systems include: state-of-the-art statistical analysis tools; geospatial visualization tools; data discovery, extraction, and delivery tools; and environmental/public health linkage information. As part of its mandate, EPHTS issues public health advisories and forecasts of environmental conditions that have consequences for human health. Through a NASA-funded partnership between the University of New Mexico and the University of Arizona, NASA Earth Science results are fused into two existing models (the Dust Regional Atmospheric Model (DREAM) and the Community Multiscale Air Quality (CMAQ) model) in order to improve forecasts of atmospheric dust, ozone, and aerosols. The results and products derived from the outputs of these models are made available to an Open Source mapping component of the New Mexico EPHTS. In particular, these products are integrated into a Django content management system using GeoDjango, GeoAlchemy, and other OGC-compliant geospatial libraries written in the Python and C++ programming languages. Capabilities of the resultant mapping system include indicator-based thematic mapping, data delivery, and analytical capabilities. DREAM and CMAQ outputs can be inspected, via REST calls, through temporal and spatial subsetting of the atmospheric concentration data across analytical units employed by the public health community. This paper describes details of the architecture and integration of NASA Earth Science into the EPHTS decision-support system.
NASA Astrophysics Data System (ADS)
Merritt, Brett W.
Understanding is widely touted to be of paramount importance for education. This is especially true in science education research and development where understanding is heralded as one of the cornerstones of reform. Teachers are expected to teach for understanding and students are expected to learn with understanding. This dissertation is an empirical study of the concept of understanding. After analyzing various constructions of understanding in current U.S. education literature, I suggest that understanding is defined by five distinct features---they are knowledge (or knowledge base), coherence, transfer, extrapolation, and cognition--- and that these features are heavily informed and shaped by the psychological sciences. This relationship is neither good nor bad, I argue, but it means that teaching for and learning with understanding are not heavily informed and shaped by, for example, the natural sciences. Drawing from historical, philosophical, and anthropological perspectives of science, but especially from the work of Bruno Latour, I enact a radical revision(ing) of psychological notions such as "abstraction" and "transfer." The two main purposes of this re-visioning are (1) to draw critical attention to particular characteristics of a cognitive learning theory that emphasizes abstract concepts, and (2) to align many of the principles and tools used in science education more closely with those used in empirical scientific research. Finally, by bringing some examples of teaching and learning from an undergraduate biology classroom into conversation with both psychological and empirical practices and perspectives, I suggest that problematizing the current construction of understanding creates much needed room in mainstream science education for more empirical forms of learning and styles of teaching. A shift to such forms and styles, I conclude, should prove to be more inclusive and less constraining for both students and teachers.
Alkali Halide Opacity in Brown Dwarf and Cool Stellar Atmospheres: A Study of Lithium Chloride
NASA Astrophysics Data System (ADS)
Kirby, K.; Weck, P. F.; Schweitzer, A.; Stancil, P. C.; Hauschildt, P. H.
2003-12-01
Recent thermochemical equilibrium calculations have revealed the important role played by lithium chloride in the lithium chemistry of cool dwarf atmospheres (K. Lodders 1999, ApJ 519, 793). Indeed, LiCl appears to be the dominant Li-bearing gas over an extended domain of the (P,T) diagram, typically for temperatures below 1500 K. LiCl has a large dipole moment in its ground electronic state which can give rise to intense rovibrational line spectra. In addition, LiCl can make dipole transitions to several low-lying unbound excited states, causing dissociation of the molecule. For these reasons, LiCl may be a significant source of line and continuum opacity in brown dwarf and cool stellar atmospheres. In this work, we report calculations of complete lists of line oscillator strengths and photodissociation cross sections for the low-lying electronic states of LiCl. We have performed single- and double-excitation configuration interaction calculations using the ALCHEMY ab initio package (Mc Lean et al. 1991, MOTECC 91, Elsevier, Leiden) and obtained the potential curves and the corresponding dipole transition moment functions between the X 1Σ ^+ ground state and the B 1Σ ^+ and A 1Π excited states. The resulting line oscillator strengths and molecular photodissociation cross sections have been included in the PHOENIX stellar atmosphere code (Hauschildt & Baron 1999, J. Comput. App. Math. 102, 41). The new models, calculated using spherical geometry for all gravities considered, also incorporate our latest database of nearly 670 million molecular lines, and updated equations of state (EOS). This work was supported in part by NSF grants AST-9720704 and AST-0086246, NASA grants NAG5-8425, NAG5-9222, and NAG5-10551 as well as NASA/JPL grant 961582.
NASA Astrophysics Data System (ADS)
Perry, David S.; Miller, Anthony; Amyay, Badr; Fayt, André; Herman, Michel
2010-04-01
The link between energy-resolved spectra and time-resolved dynamics is explored quantitatively for acetylene (12C2H2), ? with up to 8600 cm-1 of vibrational energy. This comparison is based on the extensive and reliable knowledge of the vibration-rotation energy levels and on the model Hamiltonian used to fit them to high precision [B. Amyay, S. Robert, M. Herman, A. Fayt, B. Raghavendra, A. Moudens, J. Thiévin, B. Rowe, and R. Georges, J. Chem. Phys. 131, 114301 (2009)]. Simulated intensity borrowing features in high resolution absorption spectra and predicted survival probabilities in intramolecular vibrational redistribution (IVR) are first investigated for the v 4 + v 5 and v 3 bright states, for J = 2, 30 and 100. The dependence of the results on the rotational quantum number and on the choice of vibrational bright state reflects the interplay of three kinds of off-diagonal resonances: anharmonic, rotational l-type, and Coriolis. The dynamical quantities used to characterize the calculated time-dependent dynamics are the dilution factor φ d, the IVR lifetime τ IVR , and the recurrence time τ rec. For the two bright states v 3 + 2v 4 and 7v 4, the collisionless dynamics for thermally averaged rotational distributions at T = 27, 270 and 500 K were calculated from the available spectroscopic data. For the 7v 4 bright state, an apparent irreversible decay of is found. In all cases, the model Hamiltonian allows a detailed calculation of the energy flow among all of the coupled zeroth-order vibration-rotation states.
To succeed in the long-term, focus on the middle-term.
Moore, Geoffrey A
2007-01-01
When a mature company fails to endure over the long term, it's often due to the "Horizon 2 vacuum," argues Moore, author of Crossing the Chasm and several other books on innovation strategy, and managing director of the consulting firm TCG Advisors. The reference is to the strategic horizons outlined by McKinsey's Mehrdad Baghai and colleagues in The Alchemy of Growth: Horizon 1 is today's cash-generating business, Horizon 2 is the set of innovations just being commercialized, and Horizon 3 consists of forward-thinking R&D. Most companies understand they must invest in their future, so the funding and management of Horizon 3 is not the problem. The trouble starts when those innovations are brought to market and must compete with the mainstay business for company resources. They disappear from top management's radar screen and suffer a level of neglect few ventures could survive. Cisco Systems is one company that has recognized the problem and tried to address it. To begin with, CEO John Chambers has insulated Horizon 2 projects from many of the pressures of Horizon 1--for example, by reorchestrating sales coverage so that emerging markets won't be neglected. He has also kick-started some Horizon 2 businesses by augmenting them with acquisitions, increasing their scale, and giving them more management attention. For the same reason, he has challenged his head of product development to think in terms of new businesses, not simply new products--knowing that the latter tend to get lost in salespeople's bags. Most important, Cisco is handicapping its Horizon 2 projects so that they need not compete head-to-head with established businesses. Their success is judged by metrics that are appropriate to new businesses, and they are given the benefit of Cisco's best managerial talent.
Origins Of The Elements - An Educational Web Site
NASA Astrophysics Data System (ADS)
Samarasingha, Iranga; Ivans, I. I.
2011-01-01
This poster introduces a new and unique web site "ORIGINS OF THE ELEMENTS" to the astronomy and physics communities. The main objective of our site is to provide a useful reference guide to the origins of the elements for researchers, educators and students. Only a very few of the lightest elements have their origins at the earliest cosmological ages of the Universe, the Big Bang. Most of the elements found on the Earth, and in the rest of the Universe, owe their primary existence to stellar nucleosynthesis, either during the course of the energy generation lifetimes of stars, or in the exploding supernovae of stars at the end of their lives. A by-product of stellar energy generation and exploding supernovae is alchemy -- the ashes of the energy generation contribution of one element is another, more massive element. Although various reference sources are available to learn about nucleosynthesis, it's a challenging task to uncover appropriate study materials. In this single site, we present both data and recent research results in a concise and attractive structure. Using tables and charts, the material is presented in a multi-level style. For each of the elements in the periodic table, and for each of the stable isotopes in the chart of the nuclides, the site gives a clear visualization of their corresponding nucleosynthetic origins. As a consequence, the charts afford an insight into the patterns of nucleosynthesis. Moreover, the web site provides the student with an intuition to the relative distributions of those elements. Another important feature of our site is that users have direct access to the tabulated elemental abundances (both theoretical and observed) of stars and meteorites.
Salzmann-Erikson, Martin; Eriksson, Henrik
2018-02-01
Technology in the healthcare sector is undergoing rapid development. One of the most prominent areas of healthcare in which robots are implemented is nursing homes. However, nursing and technology are often considered as being contradictory, an attitude originating in the view of "the natural" versus "the artificial". Social media mirror this view, including in attitudes and societal debates regarding nursing and care robots. However, little is known about this topic in previous research. To examine user behaviour in social media platforms on the topic of nursing and care robots. A retrospective and cross-sectional observation study design was applied. Data were collected via the Alchemy streaming application programming interface. Data from social media were collected from 1 January 2014 to 5 January 2016. The data set consisted of 12,311 mentions in total. Nursing and care robots are a small-scale topic of discussion in social media. Twitter was found to be the largest channel in terms of volume, followed by Tumblr. News channels had the highest percentage of visibility, while forums and Tumblr had the least. It was found in the data that 67.9% of the mentions were positive, 24.4% were negative and 7.8% were neutral. The volume and visibility of the data on nursing robots found in social media, as well as the attitudes to nursing robots found there, indicate that nursing care robots, which are seen as representing a next step in technological development in healthcare, are a topic on the rise in social media. These findings are likely to be related to the idea that nursing care robots are on the breakthrough of replacing human labour in healthcare worldwide.
Bentley, A R; Horsnell, R; Werner, C P; Turner, A S; Rose, G A; Bedard, C; Howell, P; Wilhelm, E P; Mackay, I J; Howells, R M; Greenland, A; Laurie, D A; Gosman, N
2013-04-01
Flowering is a critical period in the life cycle of flowering plant species, resulting in an irreversible commitment of significant resources. Wheat is photoperiod sensitive, flowering only when daylength surpasses a critical length; however, photoperiod insensitivity (PI) has been selected by plant breeders for >40 years to enhance yield in certain environments. Control of flowering time has been greatly facilitated by the development of molecular markers for the Photoperiod-1 (Ppd-1) homeoloci, on the group 2 chromosomes. In the current study, an allelic series of BC2F4 lines in the winter wheat cultivars 'Robigus' and 'Alchemy' was developed to elucidate the influence on flowering of eight gene variants from the B- and D-genomes of bread wheat and the A-genome of durum wheat. Allele effects were tested in short, natural, and extended photoperiods in the field and controlled environments. Across genetic background and treatment, the D-genome PI allele, Ppd-D1a, had a more potent effect on reducing flowering time than Ppd-B1a. However, there was significant donor allele effect for both Ppd-D1a and Ppd-B1a, suggesting the presence of linked modifier genes and/or additional sources of latent sensitivity. Development of Ppd-A1a BC2F4 lines derived from synthetic hexaploid wheat provided an opportunity to compare directly the flowering time effect of the A-genome allele from durum with the B- and D-genome variants from bread wheat for the first time. Analyses indicated that the reducing effect of Ppd-A1a is comparable with that of Ppd-D1a, confirming it as a useful alternative source of PI.
[The therapeutics of Paracelsus with reference to natural philosophy, alchemy and psychology].
Schott, H
1993-01-01
The controversial reception of Paracelsus is still going on. The crucial question is whether he is a man of the Middle Ages or of modern times. It is not possible to give a simple answer. We have to study the writings of Paracelsus within the scientific and cultural context of the Renaissance. This period is characterized by a new concept of natural philosophy. The theory of signature tries to read or translate certain constellations within the natural environment as a secret code. The idea of a sympathetic correspondence between natural bodies or substances implies the possibility of magical healing. A wellknown example is the preparation of the 'weapon salve'. There are two realities of spiritual powers at the same time: demons from the outside of the human body and powers of the mind from its inside which influence the body functions. The natural philosophy of the Renaissance tries to 'naturalize' the demons as a complement of matter. Paracelsus reflects the ideas of his time. The human being has got two bodies: a visible one which belongs to earth and an invisible one which belongs to heaven. The 'philosopher' as a pharmacist and a doctor has to detect the invisible body corresponding with the celestial world (stars, planets) by analysing the manifest astrological signs. The alchemical preparation of remedies has to purify the specific healing substances ('arcana') from the crude material. The pharmacist and doctor just imitates artificially the quasi alchemical metabolic process of nature itself continuing and finishing it. Paracelsus' concept of imagination ('imaginatio') implies a psychosomatic model how far spiritual powers can influence the body functions. Paracelsus stresses radically the importance of suggestions as a source of illness. The synchronical concepts are confusing today. Knowledge and superstition, scientific rationality and irrational speculations come together and can hardly be separated. Nevertheless, at the end of the 20th century we may have more mental relations to this scenario than we are able to realize it at the moment.
Comparative electronic structure of a lanthanide and actinide diatomic oxide: Nd versus U
NASA Astrophysics Data System (ADS)
Krauss, M.; Stevens, W. J.
2003-01-01
Using a modified version of the Alchemy electronic structure code and relativistic pseudopotentials, the electronic structure of the ground and low lying excited states of UO, NdO, and NdO + have been calculated at the Hartree-Fock (HF) and multiconfiguration self-consistent field (MCSCF) levels of theory. Including results from an earlier study of UO + this provides the information for a comparative analysis of a lanthanide and an actinide diatomic oxide. UO and NdO are both described formally as M +2 O -2 and the cations as M +3 O -2 , but the HF and MCSCF calculations show that these systems are considerably less ionic due to large charge back-transfer in the πorbitals. The electronic states putatively arise from the ligand field (oxygen anion) perturbed f 4 , sf 3 , df 3 , sdf 2 , or s 2 f 2 states of M +2 and f 3 , sf 2 or df 2 states of M +3 . Molecular orbital results show a substantial stabilization of the sf 3 or s 2 f 2 configurations relative to the f 4 or df 3 configurations that are the even or odd parity ground states in the M +2 free ion. The compact f and d orbitals are more destabilized by the anion field than the diffuse s orbital. The ground states of the neutral species are dominated by orbitals arising from the M +2 sf 3 term, and all the potential energy curves arising from this configuration are similar, which allows an estimate of the vibrational frequencies for UO and NdO of 862 cm -1 and 836 cm -1 , respectively. For NdO + and UO + the excitation energies for the Ωstates were calculated with a valence configuration interaction method using ab initio effective spin-orbit operators to couple the molecular orbital configurations. The results for NdO + are very comparable with the results for UO + , and show the vibrational and electronic states to be interleaved.
[Early career of Michael Sendivogius].
Prinke, Rafał T
2012-01-01
One of the most influential alchemical authors of the early modern period was Michael Sendivogius whose early life is shrouded in mystery. He may be labelled the most famous Polish scientific writer between Copernicus and Marie Skłodowska-Curie, but because of the difficulties involved in researching the biography of any alchemist, there has been relatively little interest in him among Polish historians. The early work of Roman Bugaj (author of the still fundamental monograph) and Włodzimierz Hubicki (who made his research available to the international community) has been continued only by the English-born Zbigniew Szydło and the author of this article. The roots of many legends about Sendivogius were three mid-17th century short biographies, none of which is trustworthy, so it is crucial to verify the received myth and the version constructed in the 1960's and 1970's with primary sources and evidence from the recent "new historiography of alchemy". The present article examines them in the light of newly discovered sources and reinterpretation of the old ones. The genealogy of the Sedzimir family is discussed at length to show that Sendivogius most probably was not its member but only a pretender in order to assume (or prove) the status of a nobleman. Several possible hypotheses about his origins are presented. He is known to have studied at three universities (Leipzig, Vienna and Altdorf) but authors of early panegyrics dedicated to Sendivogius list more universities which he may have attended. The most interesting is that of Cambridge, listed as the first one, because practically no Poles or Czechs went there at the time. Finally, his marriage to Veronica Stiebar, a wealthy widow of a Franconian knightly family, and her interesting family relationships (links to Erasmus, Camerarius, Paracelsus and the original Doctor Faustus) are discussed. The period covered is that before Sendivogius moved to Prague in about 1597, having already been a courtier of Rudolf II since early 1594.
Photocathodes for RF photoinjectors
NASA Astrophysics Data System (ADS)
Michelato, P.
1997-02-01
Over the past ten years photocathodes have been extensively used as high-brightness electron sources in RF guns. In this paper, I present a general review of the alkali-based high quantum efficiency (QE) photoemitters (e.g. Cs 3Sb, K 2CsSb and Cs 2Te), together with a comparative analysis of the different preparation procedures and the results obtained, both in the preparation chambers and in RF guns. The need to increase the photocathode reliability has provided the impetus to get an R&D activity to go over the alchemy of photocathode preparation procedure. In this paper, I will discuss the results so far obtained in different laboratories, both by using traditional investigation strategy (e.g. QE and RF behavior) and by means of surface science techniques as Auger Electron Spectroscopy (AES) and X-ray Photoelectron Spectroscopy (XPS). Alkali antimonides have been used at first in the RF gun due to the high QE response to the green light of the Nd:YLF second-harmonic radiation. Measurements have confirmed the high reactivity of the alkali antimonide photocathodes to the residual gases: this fact makes their use in RF guns not practical, mainly for short lifetimes. Further investigations have shown that the choice of the substratum preparation procedure and chemical composition plays a fundamental role in the photocathode performance, both from the point of view of the QE and the operative lifetime and ruggedness to gas exposition. Cesium telluride (Cs 2Te) prepared on a molybdenum substratum seems to be, nowadays, the best compromise, in terms of preparation procedure reliability and ruggedness, that now the characteristics and drawbacks of this material are well understood (e.g. the need of an UV laser source). Future possible developments will be discussed. In particular, the measurement and the control of the thermal emittance and the time response could be an important task.
Electronic Structure of Transition Metal Clusters, Actinide Complexes and Their Reactivities
DOE Office of Scientific and Technical Information (OSTI.GOV)
Krishnan Balasubramanian
2009-07-18
This is a continuing DOE-BES funded project on transition metal and actinide containing species, aimed at the electronic structure and spectroscopy of transition metal and actinide containing species. While a long term connection of these species is to catalysis and environmental management of high-level nuclear wastes, the immediate relevance is directly to other DOE-BES funded experimental projects at DOE-National labs and universities. There are a number of ongoing gas-phase spectroscopic studies of these species at various places, and our computational work has been inspired by these experimental studies and we have also inspired other experimental and theoretical studies. Thus ourmore » studies have varied from spectroscopy of diatomic transition metal carbides to large complexes containing transition metals, and actinide complexes that are critical to the environment. In addition, we are continuing to make code enhancements and modernization of ALCHEMY II set of codes and its interface with relativistic configuration interaction (RCI). At present these codes can carry out multi-reference computations that included up to 60 million configurations and multiple states from each such CI expansion. ALCHEMY II codes have been modernized and converted to a variety of platforms such as Windows XP, and Linux. We have revamped the symbolic CI code to automate the MRSDCI technique so that the references are automatically chosen with a given cutoff from the CASSCF and thus we are doing accurate MRSDCI computations with 10,000 or larger reference space of configurations. The RCI code can also handle a large number of reference configurations, which include up to 10,000 reference configurations. Another major progress is in routinely including larger basis sets up to 5g functions in thee computations. Of course higher angular momenta functions can also be handled using Gaussian and other codes with other methods such as DFT, MP2, CCSD(T), etc. We have also calibrated our RECP methods with all-electron Douglas-Kroll relativistic methods. We have the capabilities for computing full CI extrapolations including spin-orbit effects and several one-electron properties and electron density maps including spin-orbit effects. We are continuously collaborating with several experimental groups around the country and at National Labs to carry out computational studies on the DOE-BES funded projects. The past work in the last 3 years was primarily motivated and driven by the concurrent or recent experimental studies on these systems. We were thus significantly benefited by coordinating our computational efforts with experimental studies. The interaction between theory and experiment has resulted in some unique and exciting opportunities. For example, for the very first time ever, the upper spin-orbit component of a heavy trimer such as Au{sub 3} was experimentally observed as a result of our accurate computational study on the upper electronic states of gold trimer. Likewise for the first time AuH{sub 2} could be observed and interpreted clearly due to our computed potential energy surfaces that revealed the existence of a large barrier to convert the isolated AuH{sub 2} back to Au and H{sub 2}. We have also worked on yet to be observed systems and have made predictions for future experiments. We have computed the spectroscopic and thermodynamic properties of transition metal carbides transition metal clusters and compared our electronic states to the anion photodetachment spectra of Lai Sheng Wang. Prof Mike Morse and coworkers(funded also by DOE-BES) and Prof Stimle and coworkers(also funded by DOE-BES) are working on the spectroscopic properties of transition metal carbides and nitrides. Our predictions on the excited states of transition metal clusters such as Hf{sub 3}, Nb{sub 2}{sup +} etc., have been confirmed experimentally by Prof. Lombardi and coworkers using resonance Raman spectroscopy. We have also been studying larger complexes critical to the environmental management of high-level nuclear wastes. In collaboration with experimental colleague Prof Hieno Nitsche (Berkeley) and Dr. Pat Allen (Livermore, EXAFS) we have studied the uranyl complexes with silicates and carbonates. It should be stressed that although our computed ionization potential of uranium oxide was in conflict with the existing experimental data at the time, a subsequent gas-phase experimental work by Prof Mike Haven and coworkers published as communication in JACS confirmed our computed result to within 0.1 eV. This provides considerable confidence that the computed results in large basis sets with highly-correlated wave functions have excellent accuracies and they have the capabilities to predict the excited states also with great accuracy. Computations of actinide complexes (Uranyl and plutonyl complexes) are critical to management of high-level nuclear wastes.« less
Arnaldo Da Villanova medieval physician (1235-1311). A first approach.
Ricciardi, Biagio; Ricciardi, Elisabetta; Ricciardi, Carlo Alberto
2016-02-01
Arnaldo de Villanova, was a Catalan Physician, born in Villanova de Grau, a suburb of Valencia - Spain about 1235. He died off the coast of Genoa in 1311 during a sea voyage departing from Messina in Sicily, during a diplomatic mission by Pope Clement V in Avignon on orders by the King of Sicily. He was a so famous and clever scientist of the thirteenth century, to give his name to the Universitary Hospital of Montpellier - France. His interests ranged from theology, to politics, medicine, and anymore alchemy. He was an adviser and physician of Kings of Aragon, like Peter III the Great (1276-1285) and James II the Right (1285-1327), of Robert of Angi (1309-1343) of Naples, and of Popes, like Innocenzo V (1276), Bonifacio VIII (1294-1303), Benedetto XI (1303-1304), Clemente V (1305-1314), and of the King of Sicily Federico II of Aragon (1296-1337). For the Pope Bonifacio VIII, suffering from renal colic due to kidney stones, he prescribed Hydrotherapy with Fiuggi Thermal water, that was specially transported for him from its source to Rome and Anagni, in jars wrapped in coarse carpets or wool fabrics, to better maintain the source temperature. In addition in July of 1301, he also produced an astrological seal (Talisman) made of gold loaded of virtues, obtained exposing the seal to the power of the Sun, in those days in the Leo Constellation. This seal was worn by the Pope in an hernial belt of leather to support the kidney,probably to improve hisnephroptosis. Arnaldo produced this seal according to what was described in the book Picatrix - The goal of the wise of the Arabic astronomer and alchemist "Abū l-Qāsim Maslama b.- Ahmad al-Majriti, known with the pseudonym Ghayat al hakim died in Cordova about 1008. Ten years later, after his mysterious death at sea on a Sicilian royal ship, his body was not buried at sea, but was reported in Sicily and buried in the Federician Castle of Montalbano of Elicona at the end of Peloritans Mountains near Milazzo, about 90 km from Messina, where he loved to stay and to write.
[Corpus Hermeticum in history].
Bugaj, R
2001-01-01
The originator and founder of hermetism was the mythical Hermes Trismegistos, a deity of the syncretic Hellenistic religion that came into being through the identification of the Greek god Hermes with the Egyptian god Thot. In later Hellenistsic times various hermetic writers considered Hermes Trismegistos to have been a historical personage, a king, prophet and philosopher (physician), as well as author of many widely disseminated writings that made up the so-called Corpus Hermeticum (eighteen separate treatises from the 2nd-4th centuries AD) and the so-called Emerald Table (Tabula Smaragdina). The Corpus Hermeticum is a collection of treatises of a philosophical, religious, theological as well as theosophical nature. The collection played an important role in the development of the philosophy of alchemy and hermetism, and formed the basis for an alchemist philosophy of nature. There are currently two views among scholars on the origins of hermetism. According to one, hermetism derived directly from Egypt, while according to the other it orginated in Greece. In the years 1945-46 a number of hermetic texts forming part of the now famous gnostic "library" were discovered in Nag-Hammadi (Chenosboskion) in Upper Egypt. The Coptic texts from Nag-Hammadi date from the middle of the 4th century AD, and according to experts are translations from the Greek. Some authors (R. Reitzenstein and T. Zieliński) have suggested that along with the appearance in Egypt of the Hermetic Books, attributed to Hermes Trismegistos, there also appeared a new god in Egypt, Poimandres, and a new religion was established, hermetism, which competed for influence with Christianity. The present article discusses the main of the hermetic treatises, including Poimandres, which contains an account of the creation of the world. The article also discusses the reasons for the decline of hermetism as a religion and stresses that in spite of this decline the doctrine managed to survive in the form of alchemic hermetism, which played an important role in the culture of the Renaissance. The article also cites the voluminous work by W. Scott and A. S. Ferguson (1924-1936), and A. D. Nock and A. -J. Festugiére (1945-1964), which contains contemporary, English and French, commentaries on and translations of the Corpus Hermeticum texts.
Harmonious colors: from alchemy to science
NASA Astrophysics Data System (ADS)
Beretta, Giordano B.; Moroney, Nathan M.
2012-01-01
There is a very long tradition in designing color palettes for various applications, going back to at least the Upanishad. Although color palettes have been influenced by the available colorants, starting with the advent of aniline dyes in the late 1850s there have been few physical limits on the choice of individual colors. This abundance of choices exacerbates the problem of limiting the number of colors in a palette, i.e., in keeping them into a manageable quantity. For example, it is not practical for a car company to offer each model in hundreds of colors. Instead, for each model year a small number of color palettes is offered, each containing the colors for the body, trim, interior, etc. Another example is the fashion industry, where in addition to solid colors there are also patterns, leading to a huge variety of combinations that would be impossible to stock. The traditional solution is that of "color forecasting." Color consultants assess the sentiment or affective state of a target customer class and compare it with new colorants offered by the industry. They assemble a limited color palette, name the colors according to the sentiment, and publish their result. Textile manufacturers will produce fabrics in these colors and fashion designers will design clothes, accessories, and furniture based on these fabrics. Eventually, the media will communicate these forecasts to the consumers, who will be admired by their cohorts when they choose colors from the forecast palette, which by then is widely diffused. The color forecasting business is very labor intensive and difficult, thus for years computer engineers have tried to come up with algorithms to design harmonious color palettes, alas with little commercial success. For example, Johannes Itten's color theory has been implemented many times, but despite Itten's success in the Bauhaus artifacts, the computer tools have been of little utility. Indeed, contrary to the auditory sense, there is no known physiological mechanism sustaining harmony and the term "harmonious" just has the informal meaning of "going well together." We argue that the intellectual flaw resides in the belief that a masterful individual can devise a "perfect methodology" that the engineer can then reduce to practice in a computer program. We suggest that the correct approach is to consider color forecasting as an act of distillation, where a palette is digested from the sentiment of a very large number of people. We describe how this approach can be reduced to an algorithm by replacing the subjective process with a data analytic process.
NASA Astrophysics Data System (ADS)
Pedentchouk, Nikolai; Eley, Yvette; Frizell-Armitage, Amelia; Uauy, Cristobal
2015-04-01
The use of the 2H/1H composition of terrestrial plants in climate and ecology studies depends on fundamental understanding of the processes within the plant that control fractionation of these two isotopes. Little is currently known about the extent of 2H/1H fractionation at different steps of biosynthesis, after the initial H uptake following leaf water photolysis. Knowing this effect is particularly important when seeking to interpret the 2H/1H composition of leaf wax biomarkers from plants that differ in the amount and type of individual compound classes in their leaf waxes. The purpose of this study was to investigate the link between the quantity and distribution of n-alkyl lipids in leaf waxes and their isotopic composition. We used a genetic approach to suppress glaucousness in 2 varieties of wheat (Alchemy and Malacca), which resulted in glaucous and non-glaucous phenotypes of both varieties. Both phenotypes were then grown outdoors under identical environmental conditions in central Norfolk, UK. At the end of the growing season, the plants were sampled for soil water, leaf water, and leaf wax isotopic measurements. Comparison of the leaf wax composition of the non-glaucous and glaucous phenotypes revealed that the non-glaucous varieties were characterised by the absence of diketones and a greater concentration of n-alkanes and primary alcohols.. Our results showed very small differences between glaucous and non-glaucous varieties with regard to soil (mean values, <2 per mil) and leaf (<1 per mil) water 2H/1H. Conversely, there was 15-20 and 10-15 per mil 2H-depletion in the C29 and C31 n-alkanes, respectively, from the non-glaucous phenotype. This 2H-depletion in the non-glaucous phenotype demonstrated that the suppression of diketone production and the increase in n-alkane and primary alcohol concentrations are linked with a shift in the 2H/1H composition of n-alkanes. The initial results of this work suggest that plants using the same environmental water, subjected to the same effects of evapotranspiration, but which differ in the amount and composition of leaf wax compounds, can exhibit large variation in their n-alkane 2H/1H. Our current work on determining the 2H/1H composition of other n-alkyl lipids from these plants will provide further details regarding the role of biosynthesis in controlling 2H/1H fractionation within leaf waxes.
Spurio, Maria Grazia
2016-09-01
For a long time, terms like "mind" and "emotion" have rarely been taken into account, not even mentioned in the medical texts. The latest scientific researches, including the studies of Candace Pert, on the contrary, have emphasized that the entire body thinks, because every single cell hears, and feels emotions. The international researcher has discovered the endocrines and a vast number of neuropeptides, that work as an "information network" that interconnects the entire body, the "psychic" molecules are transmitted and travel, communicating information as in a circular and recursive body - mind mechanism. This is a sort of body and mind functional identity, which is different in each person, because each person is a unique universe, and the body is the place where mind and body meet in a unique and unrepeatable alchemy. So, if it is true that only in the body the secret of its potential for development and transformation is well hidden, it is also true that this secret is unique for each of us. Then, the strategic therapy becomes 'tailor-made', and the knowledge of the body component is essential to unlock behavior patterns and planning new ones, in order to improve relationships and the quality of life, and enhance the sense of well-being. People are not as simple containers which merely record external incitements, on the contrary, they are able to evaluate and weigh what happens around. Depending on the meaning attributed to each stimulus, a stress response of different magnitude and duration is activated, this can be considered functional or dysfunctional. Many recent studies, in fact, states that there is a significant correlation between the coping strategy chosen and the onset of a disease. According to the theory of 'psychogenic tumor', for example, anyone can potentially develop cancer, but only those who do not have the psychological strength to resist disease get sick. No matter what is the theoretical framework and the conclusion adopted, we go towards a consensus of considering body and mind as a part of a unique and complex functional identity. As a consequence of this completely new approach on how to consider the wellbeing and health, researchers suggest that the goal of a satisfactory physical and mental balance can be achieved through a transversal approach to the various disciplines (psychotherapy, surgical, nutritionist, medical aesthetics and medicine in general). According to this bio-psycho-social approach, each person should be approached in his entirety, bodily and psychological; each individual should be 'hosted' in a sort of 'Body and Mind' zone, where the entire body is able to think.
BOOK REVIEW: Tycho Brahe and Prague: Crossroads of European Science
NASA Astrophysics Data System (ADS)
Sterken, C.; Christianson, J. R.; Hadravová, A.; Hadrava, P.; Solc, M.
2003-01-01
The 16th volume of the Acta Historica Astronomiae is the Proceedings of the International Symposium on the History of Science in the Rudolphine Period. The meeting was held in Prague from 22 to 25 October 2001, on the 400th anniversary of Tycho's sudden death, and was attended by approximately 65 scientists and historians. The volume contains 36 contributions dealing with the life and work of Tycho Brahe, the astronomy of the era, and many cultural aspects of Rudolphine Prague. One of the first papers is an eye-opener on the fact that Tycho Brahe was a cosmologically-driven observer. This is followed by a very illuminating paper on gender roles in science in the late 16th century, with emphasis on the role of Sophie Brahe, Tycho's youngest sister. Several subsequent papers reveal the existence of barely known links between Tycho and his contemporaneous colleagues. These extremely-well documented papers also deal with the broader philosophical investigation he was involved in, viz. meteorology, medicine, astrology, alchemy and even theology. Important names of Tycho's days are Petrus Severinus, Johannes Pratensis, Theophrastus Paracelsus, John Craig, Ursus (Nicolai Reymers Baer) etc. Very illuminating is the information on the relations between Tycho and the Jesuits in Prague, explaining the reason why this order was very supportive of the Tychonic cosmological model. The relationsship with Kepler, and also Kepler's observational activities (after Tycho's death) are highlighted as well as the hideous mode of communication between Galileo and Kepler. More than one paper deals with the accuracy and precision of Tycho's observations, and the causal impact of this accuracy on the scientific revolution. Another study discusses the study of Tycho's handwriting, this paper brings the aditional bonus of a list of accessible works which contain notes by him. One very interesting project was Brahe's proposal to the Republic of Venice to determine the exact latitudes of geographical points at different epochs in order to prove that the value of the precession is constant, which would support his cosmological model. Technically, the book has several regrettable shortcomings: there is no subject nor object index, the layout is rather heterogeneous (some papers have figure captions and others not, only 7 papers have a list of references at the end, some papers are structured in Sections but several are not). Most references appear in footnotes, and several of these footnotes cover a full page or even more, a truly irritating situation for the reader. About 10% of the papers are written in German, the remaining are in English. Despite the editorial imperfections, this is a delightful book, a treasure trove of detailed information which usually is not available in textbooks on the history of astronomy. It is one of these rare proceedings that makes the reader truly regret the fact that he or she could not participate at the conference. This is great informative value for the money.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Padhi, Payodhar; Sahoo, G.; Das, K.
The use of metals and minerals in the traditional Indian system of medicine known as aired is very common and is practiced since seventh century B.C. Metals were reduced to calcined powder form for medicinal purpose. For detoxification, a further step of purification of the metals and minerals with different vegetable extracts was practiced. The people of East India were using mercury and its sulfide as medicine. Gradually this secret was leaked to Arabic physicians who used mercury in skin ointment. Subsequently Italian Physicians adopted Arabic prescriptions of mercurial ointments for skin diseases. In the olden days, metals and mineralsmore » were impregnated with decoction and juice of vegetables and animal products like milk and fat for purification. These were then reduced to fine particles by milling with a pestle and mortar. It was known by then that the fineness of the powder had a significant influence on the color, texture, and medicinal properties as is cited by Charak. Nagarjun studied in detail the processing of metals and minerals, particularly mercury and the influence of the processing parameters on the medicinal values. Mercury is unique in many aspects. Indian alchemy developed a wide variety a chemical processes for the ostensible transmutation of metals and preparation of elixir of life, in which mercury occupied a prime position .The present investigation attempts to use the traditional methods as prescribed in the ancient texts to prepare mercury sulfide in both red and black form for medicinal use. XRD, SEM and HRTEM investigations of the sulfides obtained shows that the ancient Indians were able to produce nano-sized powders. Possibly this may be taken as the earliest application of the production and use of nano powder. The study proves that even in ancient time the knowledge of nano particle synthesis was prevalent and used to enhance effectiveness of medicines. Further mercury in the free form is not acceptable in medicines. The ancient physicians could get rid of free mercury by milling and proper choice of the ratio of ingredients as is shown in the investigation by X-ray diffraction studies. In the traditional method for synthesis of mercury sulfide, mercury and pure sulfur were taken and milled in a mortar and pastel. During milling process, the white mercury and yellow sulfur yielded to a gray black colored sulfide. Synthesis of red sulfide of mercury required additional steps of heating and subsequent milling. For therapeutically application, the sulfide thus obtained needed detoxification, which was done using organic extracts. In the present investigation, the same method was followed to synthesize the sapphires and the product was characterized using modern methods like XRD, SEM and HRTEM. With increase in milling time the fineness of the powder increases, which increases the efficacy of the medicine, and free mercury, which is not desirable for medicinal application is found to decrease. The powder obtained at the end of 48 hours of milling is found to be of a size finer than l0nm.« less
NASA Astrophysics Data System (ADS)
Padhi, Payodhar; Sahoo, G.; Das, K.; Ghosh, Sudipto; Panigrahi, S. C.
2008-10-01
The use of metals and minerals in the traditional Indian system of medicine known as aired is very common and is practiced since seventh century B.C. Metals were reduced to calcined powder form for medicinal purpose. For detoxification, a further step of purification of the metals and minerals with different vegetable extracts was practiced. The people of East India were using mercury and its sulfide as medicine. Gradually this secret was leaked to Arabic physicians who used mercury in skin ointment. Subsequently Italian Physicians adopted Arabic prescriptions of mercurial ointments for skin diseases. In the olden days, metals and minerals were impregnated with decoction and juice of vegetables and animal products like milk and fat for purification. These were then reduced to fine particles by milling with a pestle and mortar. It was known by then that the fineness of the powder had a significant influence on the color, texture, and medicinal properties as is cited by Charak. Nagarjun studied in detail the processing of metals and minerals, particularly mercury and the influence of the processing parameters on the medicinal values. Mercury is unique in many aspects. Indian alchemy developed a wide variety a chemical processes for the ostensible transmutation of metals and preparation of elixir of life, in which mercury occupied a prime position .The present investigation attempts to use the traditional methods as prescribed in the ancient texts to prepare mercury sulfide in both red and black form for medicinal use. XRD, SEM and HRTEM investigations of the sulfides obtained shows that the ancient Indians were able to produce nano-sized powders. Possibly this may be taken as the earliest application of the production and use of nano powder. The study proves that even in ancient time the knowledge of nano particle synthesis was prevalent and used to enhance effectiveness of medicines. Further mercury in the free form is not acceptable in medicines. The ancient physicians could get rid of free mercury by milling and proper choice of the ratio of ingredients as is shown in the investigation by X-ray diffraction studies. In the traditional method for synthesis of mercury sulfide, mercury and pure sulfur were taken and milled in a mortar and pastel. During milling process, the white mercury and yellow sulfur yielded to a gray black colored sulfide. Synthesis of red sulfide of mercury required additional steps of heating and subsequent milling. For therapeutically application, the sulfide thus obtained needed detoxification, which was done using organic extracts. In the present investigation, the same method was followed to synthesize the sapphires and the product was characterized using modern methods like XRD, SEM and HRTEM. With increase in milling time the fineness of the powder increases, which increases the efficacy of the medicine, and free mercury, which is not desirable for medicinal application is found to decrease. The powder obtained at the end of 48 hours of milling is found to be of a size finer than l0nm.
Wijenayake, Apsara; Pitawala, Amarasooriya; Bandara, Ratnayake; Abayasekara, Charmalie
2014-09-11
Biotite mica enriched with Fe(2+) ions are widely used as a major mineral ingredient in traditional pharmaceutical science of alchemy (Rasashastra). Abhrak bhasma (mica ash), a pharmaceutical product containing treated mica, is utilized, for example, in Ayurvedic treatments for ailments such as gastritis, renal disease, skin disease and mainly in rejuvenation formulations. However, the untreated mica minerals may be harmful when used directly, as they carry considerably high amounts of trace-elements that can cause undesirable effects in the human body. In order to remove toxic factors and produce readily absorbable materials having high nutrient capacity, specific thermal and chemical treatments (purification, detoxification, particle size reduction and incineration) are performed during the preparation of Rasashastra. This review evaluates the chemical and pharmacological aspects of mica ash as well as the technological aspects of mica ash production. The detailed literature review on the chemistry and scientific basis of mica ash, its preparation techniques, mica alterations and pharmaceutical applications was carried out by using published Ayurvedic text books and research articles, available from Science Direct, on mica minerals, mica ash and their physico-chemical alteration processes and pharmacological applications. During the purification and detoxification procedures, heating followed by quenching (in ionic medium) influences the structural distortion and the development of stress-induced cracks and spallations of the micaceous plates. Thus, the efficient diffusion of the external medium takes place at successive heating and quenching steps. Acidic organic liquids and animal byproducts can enhance the cation exchange capacity and solubility of mica. Further, these natural compounds facilitate the removal of toxic-elements in the structure. When treated-mica and paddy husks are tied up in a cloth and squeezed, particle size reduction and further detoxification takes place. Leaching out of oxidized iron coatings is accelerated when the mixtures are immersed in acidic media, by which the filtrate is enriched with oxidized iron-silicate particles. These nano-oxide particles are converted into a more favorable oxidation form for human consumption when the herbometallic mixture is incinerated in closed vessels. Recent analytical data reveals that major and minor elements in mica ash are within the limits of pharmacopoeial standards for Ayurvedic formulations. Further, recent studies show that mica ash has hypoglycemic, hepatoprotective, anthelminthic and antimicrobial properties. Chemical and structural modifications in mica occur during mica-based drug preparation in traditional medicine. Purification steps particularly influence the structural distortion while heating and quenching can form nano-size particles. Carboxylic acids and other organic molecules present in quenching media serve as chemical modifiers of mica. At the same time the toxic elements are leached out from mica to the quenching media through an ion exchange process. Mica ash has been successfully used for treating liver, kidney and skin related ailments in traditional medicine, and mica ash alone or its herbo-metallic formulations have different applications. Further, the recent toxicological and analytical studies validate the traditional uses of mica ash and mica ash bearing products. Further scientific studies are needed to fully establish that mica-based pharmaceuticals are safe and devoid of toxic and long term side effects. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Perrault's experiments, a matter of soil hydrology and epistemology
NASA Astrophysics Data System (ADS)
Barontini, Stefano; Berta, Andrea; Settura, Matteo
2017-04-01
The studies conducted in the second half of the Sixteenth Century were crucial both for the hydrological knowledge and for the modern epistemology. In fact thanks to the new experiment-based scientific approach the Sun was about to be fully recognized as the engine of the hydrological cycle instead of an endogenous engine placed in the depths of the Earth, and the original Aristotelic approach to the description of the nature, based on the the four qualities (hot and cold, dry and moist), was got over. At the same time, the questions posed on the hydrological cycle and on the soil hydrology, which are hardly reproducible by means of a controlled laboratory model, severely tested the modern scientific approach at its beginning, and contributed to the development of modern epistemology. Perrault's classical book De l'origine des fontaines (On the origin of springs, 1674) is deeply rooted in these debates. In this book he performed experiments and collected many observations both to assess the water balance at the basin scale and to understand the water movement in the upper soil layers. Particularly he performed four experiments to understand whether the water could spontaneously rise within the soil from the water table and originate springs (1st and 2nd experiment), how deep the rainfall could percolate through the soil and recharge the groundwater table (3rd one), and whether salty water remained salty when rising into the soil by capillary action (4th one). In order to do so he filled with different soils a leaden pipe, 65cm long, and observed their performances against capillary rise, infiltration, percolation and water-content redistribution. The great detail of the experimental report allowed us to quantitatively re-experience the first three ones in the laboratory, with comparable results to Perrault's ones. Moreover it allowed us to recognize both the omitted data which would be needed for a complete repeatability, and the observations which leaded Perrault to misinterpretate the experiments by a physical point of view. As his interpretation of the experiments did not corroborate the hypothesis that precipitation might be at the origin of all the springs, it accepted one of the forms of the traditional scheme of water circulation. According to it, greatly productive springs should be sustained by evaporation and condensation processes taking place below the soil surface. Even if Perrault's conclusions went in the direction of the ancient opinion, not only De l'origine des fontaines is a seminal work of experimental hydrology, but also it can be regarded to as a milestone of scientific revolution. In his critique of both ancient (e.g. Aristotle) and modern scholars (e.g. Nicolas Papin) he makes use of principles drawn by the works of Bacon, Galilei and Pascal. Stating that "the first and most usual maxim of our moderns is to doubt everything", he shows deep awareness of the specific essence of scientific modernity. Moreover his rejection of alchemy, analogical reasoning and astrological influences arises from the conviction that "it is to experiments that we owe the finest knowledge we now have concerning the things of nature". According to this perspective, despite of all the difficulties of the soil-hydrologic laboratory practice, Perrault was nevertheless able to report his experiments in terms that we can properly reproduce nowadays.
NASA Astrophysics Data System (ADS)
Caserio, Marjorie C.
1999-07-01
Women who made significant contributions in the chemical sciences prior to the 20th century do not come readily to mind. Yet, as this book relates so engagingly, women have been influential in chemistry since the earliest period of recorded history. However, Women in Chemistry is more than a dated collection of biographical sketches of notable women scientists. The book highlights the main periods of history when it was possible for women to have some measure of success in the chemical sciences and focuses on their changing roles from alchemical times to the mid-20th century. By glimpsing into the life and work of individuals in the context of the time in which they lived, the authors impart a credible and moving image of the restraints imposed on aspiring women scientists and the obstacles that confronted them-making the extent of their contributions all the more remarkable. Each chapter has a theme into which are woven selected biographical sketches. Chapter 1 offers a whirlwind tour of the centuries from Babylonian times (1200 B.C.E.) through the Middle Ages and into the 17th century, giving perspective on how the various civilizations did (or did not) consider women capable of intellectual achievement or permit such of them. This short but powerful chapter invokes appreciation for the major contributions made by women in the face of enormous obstacles of prejudice, superstition (witchcraft), monastic reprisals, pseudoscience (alchemy), and denial of education. The women featured include Maria Hebraea (around 300 C.E.famed for the water bath, bain Marie), Hypatia (mathematician, 400 C.E.), Western alchemists (de Gourney and Meudrac), and Chinese alchemists. By the 18th century, science had progressed and alchemy was at an end. Though enlightened scientifically, western society still considered women's intellect inferior. But, as Chapter 2 relates, the literary salons of France nurtured intellectual discussion in society women, and it was in this context that such women pursued higher education. The role of women as "chemical assistants" to leading chemists of the day is well illustrated in the lives of du Chatelet, Paulze-Lavoisier, Picardet, and Necker de Saussure. Sadly, all this ended with the French Revolution when the woman intellectual became unacceptable. Chapter 3 focuses on a few exceptional women of the 1800-1900s who succeeded independently in their scientific work in an era when, without access to universities and financial resources, it was almost impossible to function other than as a "chemical assistant". This chapter gives a fascinating account of the life and work of five women, including Elizabeth Fulhame, who is credited with the discovery of photoreduction and the concept of catalysis, and Agnes Pockels, who, without formal education or laboratory facilities, pioneered research in surface films. By the 1850s, access to advanced education for women began in earnest. Chapter 4 tells of this radical change and its ramifications. This most readable account of the cultural conflicts that existed in Europe and the United States over educating women, admitting them to professional societies, and gaining faculty appointments is exemplified in the biographies of four U.S. women (Ellen Swallow Richards, Rachel Lloyd, Laura Linton, Ida Freund) and two Russian women (Yulya Lermontova and Vera Bogdanovskaia). Much of the content of the book resides in the remaining chapters (5-10) and covers 20th century science through 1950. The titles, Women in: Crystallography (Chapter 5), Radioactivity (Chapter 6), Biochemistry (Chapter 7), Industrial Chemistry (Chapter 8), Analytical, Education and History (Chapter 9), suggest that women favored some areas of chemistry over others. Why did they tend to congregate in certain fields? The authors give cogent reasons why this was so. They observe that, in developing fields, there was initially a collegiality among colleagues and the support of senior mentors that established a working environment in which women felt welcome and in which they could flourish. The early success of women in crystallography, radioactivity, and biochemistry encouraged other women to follow. There also seems to have been more opportunity for women in emerging fields than in more established but more competitive areas of science. The biographies of the women chemists featured are poignant accounts of their lives, their work, and the recognition they received for it. Though short, the biographies have been well researched and are well referenced, which should enable interested readers to delve more deeply into the subject if they wish. There are common threads that run through all the accounts, which the authors point to as important factors in determining success. These include encouragement in early years, particularly through sympathetic parents or close relatives; access to formal education; and family values that stress education. The encouragement of mentors is a recurrent theme, as is a hospitable working environment. Mentoring recognized as important not only for individual success but also in creating and sustaining whole areas of research (as we see in crystallography and radioactivity). Each biography documents an impressive record of achievement even when the obstacles encountered in the woman's personal as well as professional life were almost overwhelming. Regrettably, as the authors point out, most women left no personal records (or they have since been lost or destroyed), so we are denied their perspective on their life and times. Evidently, women did not feel sufficient self-worth to record their autobiographies. In fact, a feature that appears in several of the biographies is the "awful self-doubt" about their own abilities. But it is apparent that success increased self-esteem, which fueled further achievement. Other attributes necessary for success included great determination, incredible tenacity, and almost obsessive enthusiasm for chemistry. The authors are selective in their choice of biographies. They feature women on the basis of importance and interest rather than just the most notable. The crystallography chapter reveals the paradox that outstanding work is sometimes recognized (Lonsdale and Hodgkin) and sometimes not (Franklin). Chapter 6 is a fascinating account of the roller-coaster fortunes of women in radioactivity (Curie, Gleditsch, Chamie, Joliot-Curie, Perey, Brooks, Horovitz, Meitner, Noddack, and Goeppert-Mayer) and is the strongest chapter of the book. The biochemistry chapter acknowledges the work of Hoobler, Pennington, Denis, Fuller Brown, Cori, Elion, Willcock, Menten, Wrinch, and others. Industrial Chemistry was not a haven for women during the first part of this century, but the remarkable contributions of a few (Leslie, Wall, Blodgett, and Lathbury) are described in Chapter 8. The barriers for women in industry were numerous, including policy bans on married women and perceptions that women were unskilled or incapable of chemical work, even though they proved otherwise in the urgent need of wartime. Chapter 9 is a mixed bag, beginning with analytical chemists (Cremer and Miller), including surprisingly few who became prominent in education (Emma Perry Carr of Mount Holyoke and Mary Fieser of Bryn Mawr and Harvard), and ending with the famous historian of science Helen Metzger. In the concluding chapter, we are reminded of the ups and downs for women scientists in the first half of the 20th century. Blossoming educational and job opportunities led to record numbers of women in science by the early 1900s, but the numbers declined in the aftermath of World War I and to a lesser extent after World War II, as a result of changing societal attitudes when men and women compete for the same jobs. This thought-provoking book, elegantly written, concludes with the rhetorical question: will the current "second wave" of women scientists in this century be more permanent than the first, and will they play a full role in determining the nature and culture of chemistry in the 21st century. There is much to be learned from multiple readings of this interesting book.
Rodrigues, Ramon Gouveia; das Dores, Rafael Marques; Camilo-Junior, Celso G; Rosa, Thierson Couto
2016-01-01
Cancer is a critical disease that affects millions of people and families around the world. In 2012 about 14.1 million new cases of cancer occurred globally. Because of many reasons like the severity of some cases, the side effects of some treatments and death of other patients, cancer patients tend to be affected by serious emotional disorders, like depression, for instance. Thus, monitoring the mood of the patients is an important part of their treatment. Many cancer patients are users of online social networks and many of them take part in cancer virtual communities where they exchange messages commenting about their treatment or giving support to other patients in the community. Most of these communities are of public access and thus are useful sources of information about the mood of patients. Based on that, Sentiment Analysis methods can be useful to automatically detect positive or negative mood of cancer patients by analyzing their messages in these online communities. The objective of this work is to present a Sentiment Analysis tool, named SentiHealth-Cancer (SHC-pt), that improves the detection of emotional state of patients in Brazilian online cancer communities, by inspecting their posts written in Portuguese language. The SHC-pt is a sentiment analysis tool which is tailored specifically to detect positive, negative or neutral messages of patients in online communities of cancer patients. We conducted a comparative study of the proposed method with a set of general-purpose sentiment analysis tools adapted to this context. Different collections of posts were obtained from two cancer communities in Facebook. Additionally, the posts were analyzed by sentiment analysis tools that support the Portuguese language (Semantria and SentiStrength) and by the tool SHC-pt, developed based on the method proposed in this paper called SentiHealth. Moreover, as a second alternative to analyze the texts in Portuguese, the collected texts were automatically translated into English, and submitted to sentiment analysis tools that do not support the Portuguese language (AlchemyAPI and Textalytics) and also to Semantria and SentiStrength, using the English option of these tools. Six experiments were conducted with some variations and different origins of the collected posts. The results were measured using the following metrics: precision, recall, F1-measure and accuracy The proposed tool SHC-pt reached the best averages for accuracy and F1-measure (harmonic mean between recall and precision) in the three sentiment classes addressed (positive, negative and neutral) in all experimental settings. Moreover, the worst accuracy value (58%) achieved by SHC-pt in any experiment is 11.53% better than the greatest accuracy (52%) presented by other addressed tools. Finally, the worst average F1 (48.46%) reached by SHC-pt in any experiment is 4.14% better than the greatest average F1 (46.53%) achieved by other addressed tools. Thus, even when we compare the SHC-pt results in complex scenario versus others in easier scenario the SHC-pt is better. This paper presents two contributions. First, it proposes the method SentiHealth to detect the mood of cancer patients that are also users of communities of patients in online social networks. Second, it presents an instantiated tool from the method, called SentiHealth-Cancer (SHC-pt), dedicated to automatically analyze posts in communities of cancer patients, based on SentiHealth. This context-tailored tool outperformed other general-purpose sentiment analysis tools at least in the cancer context. This suggests that the SentiHealth method could be instantiated as other disease-based tools during future works, for instance SentiHealth-HIV, SentiHealth-Stroke and SentiHealth-Sclerosis. Copyright © 2015. Published by Elsevier Ireland Ltd.
EDITORIAL: Power is nothing without control Power is nothing without control
NASA Astrophysics Data System (ADS)
Demming, Anna
2012-04-01
A great deal of technological progress occurs by chance. In 1985 Harold Kroto and his colleagues at Rice University were working on experiments to understand the mechanisms by which long-chain carbon molecules are formed in interstellar space and circumstellar shells. What they found was the remarkably stable C60 molecule now referred to as Buckminster fullerene or 'bucky balls' [1]. Six years later, using an arc-discharge evaporation method similar to that used for fullerene synthesis at NEC Corporation in Japan, Sumio Ijima synthesised carbon nanotubes [2]. The extraordinary properties of these carbon nanostructures have since sparked the imagination of researchers in fields ranging from photonics and electronics to biology and medicine. But these properties depend greatly on geometrical factors, such as the chirality, length, diameter and whether they are single- or multi-walled. While it is possible to discover these fascinating materials by chance, it takes a great deal of curiosity and scientific ingenuity to reveal their unusual qualities, and their potential can only be harnessed by careful design. In this issue, Journet et al from Lyon University in France describes how far the field has come in exacting control in carbon nanotube synthesis [3] Morphological control has become key to nanotechnology synthesis. In2O3 nanowires have generated considerable interest for potential applications in thin film transistors and optoelectronic devices. But the morphology significantly affects the performance of these devices. Synthesising high-quality crystalline nanowires is crucial. Researchers in Singapore have investigated factors affecting the resulting products in vapour transport, a dominant technique for In2O3 nanowire synthesis. They successfully synthesised In2O3 nanowires, nanotowers and ultralong layered nanorods with uniform diameter, high aspect ratio and high yield by controlling the synthesis conditions [4]. A collaboration of researchers in Korea and China have shown that they can fabricate well aligned arrays of ZnO nanorods as long as 10 μm by using a preheating hydrothermal treatment [5.] The dimensions and orientations of the nanorod arrays are particularly well suited to technological applications. Researchers in the US have enhanced the gas-sensing performance of SnO2 single-crystal nanostructures by fabricating nanowires with a segmented morphology [6]. The low-diameter sections allow an optimum ratio of the radius to the Debye length. At the same time, the structures are sufficiently robust to avoid the problems associated with manipulating extremely narrow nanowires. It has been suggested that differences in fabrication methods such as annealing parameters can affect the photoluminescence from silicon quantum dots. Hao and Shen from Shanghai Jiao Tong University in China combined their data on silicon dots annealed in oxygen with that of silicon dots annealed in hydrogen and argon and used analysis of the results to identify the photoluminescence mechanism [7]. The work shows how annealing can be used to control photoluminescence properties by modifying the defect density through annealing treatment. Defects play an important role in tailoring the properties of graphene to maximise the materials potential in electronics and spintronics. Atomistic simulations of these sorts of systems can face problems due to the shear size of the calculations. Researchers in Brazil integrated a number of modelling approaches to propose a true spin filter based on realistic boron-doped zigzag singly hydrogen passivated graphene nanoribbons up to 450 nm in length [8]. The authors explain the excellent spin filtering performance in terms of different scattering probabilities at the impurity site for majority and minority spins, which consequently leads to different localization lengths. Carbon-based nanomaterials have catalysed enormous activity in nanoscale science and technology research. As Journet et al describe in their review, synthesis of these materials is now a refined art allowing considerable control over the parameters. The mechanisms behind the growth using different techniques is also understood, making the alchemy of creating these prized nanostructures into an advanced science. With these new nanomaterials researchers in nanoscale science and technology now have the power to create devices with performance attributes previously unimagined, and the advancing fine art of controlled synthesis allows these devices to be made on demand. References [1] Kroto H W, Heath J R, O'Brien S C, Curl R F and Smalley R E Nature 318 162-3 [2] Iijima S 1991 Nature B 354 56-8 [3] Journet C, Picher M and Jourdain V 2012 Nanotechnology 23 296-304 [4] Singh N, Zhang T and Lee P S 2009 Nanotechnology 20 195605 [5] Qiu J, Li X, He W, Park S-J, Kim H-K, Hwang Y-H, Lee J-H and Kim Y-D 2009 Nanotechnology 20 155603 [6]Dmitriev S, Lilach Y, Button B, Moskovits M and Kolmakov A 2007 Nanotechnology 18 055707 [7] Hao H L and Shen W Z 2008 Nanotechnology 19 055601 [8] Rocha A R, Martins T B, Fazzio A and da Silva A J R 2010 Nanotechnology 21 345202
European astronomers' successes with the Hubble Space Telescope*
NASA Astrophysics Data System (ADS)
1997-02-01
[Figure: Laguna Nebula] Their work spans all aspects of astronomy, from the planets to the most distant galaxies and quasars, and the following examples are just a few European highlights from Hubble's second phase, 1994-96. A scarcity of midget stars Stars less massive and fainter than the Sun are much numerous in the Milky Way Galaxy than the big bright stars that catch the eye. Guido De Marchi and Francesco Paresce of the European Southern Observatory as Garching, Germany, have counted them. With the wide-field WFPC2 camera, they have taken sample censuses within six globular clusters, which are large gatherings of stars orbiting independently in the Galaxy. In every case they find that the commonest stars have an output of light that is only one-hundredth of the Sun's. They are ten times more numerous than stars like the Sun. More significant for theories of the Universe is a scarcity of very faint stars. Some astronomers have suggested that vast numbers of such stars could account for the mysterious dark matter, which makes stars and galaxies move about more rapidly than expected from the mass of visible matter. But that would require an ever-growing count of objects at low brightnesses, and De Marchi and Paresce find the opposite to be the case -- the numbers diminish. There may be a minimum size below which Nature finds starmaking difficult. The few examples of very small stars seen so far by astronomers may be, not the heralds of a multitude of dark-matter stars, but rareties. Unchanging habits in starmaking Confirmation that very small stars are scarce comes from Gerry Gilmore of the Institute of Astronomy in Cambridge (UK). He leads a European team that analyses long-exposure images in the WFPC2 camera, obtained as a by-product when another instrument is examining a selected object. The result is an almost random sample of well-observed stars and galaxies. The most remarkable general conclusion is that the make-up of stellar populations never seems to vary. In dense or diffuse regions, in very young or very old agglomerations, in the Milky Way Galaxy or elsewhere, the relative numbers of stars of different masses are always roughly the same. Evidently Nature mass-produces quotas of large and small stars irrespective of circumstances. This discovery will assist astronomers in making sense of very distant and early galaxies. They can assume that the stars are of the most familiar kinds. Another surprise was spotted by Rebecca Elson in Gilmore's team, in long-exposure images of the giant galaxy M87, in the nearby Virgo cluster. It possesses globular clusters of very different ages. In the Milky Way and its similar spiral neighbour, the Andromeda galaxy, globular clusters contain the oldest stars. While M87 has ancient globular clusters too, some are different in colour and much younger. The theory is that they were manufactured during collisions of the galaxies that merged into M87, making it the egg-shaped giant seen today. If so, the absence of young globular clusters in the Milky Way may mean that our Galaxy has never suffered a major collision. Accidents in the galactic traffic Brighter than a million million suns, a quasar is the most powerful lamp in the Universe. Astronomers understand it to be powered by matter falling into a massive black hole in the heart of a galaxy. Mike Disney of the University of Wales, Cardiff, leads a European team that asks why some thousands of galaxies harbour quasars, in contrast to the billions that do not. In almost every case that he and his colleagues have investigated, using Hubble's WFPC2 camera at its highest resolution, they see the quasar's home galaxy involved in a collision with another galaxy. "It's my opinion that almost any galaxy can be a quasar," Disney says, "if only its central black hole gets enough to eat. In the galactic traffic accidents that Hubble reveals, we can visualize fresh supplies of stars and gas being driven into the black hole's clutches. My American opposite number, John Bahcall, prefers to stress those quasar hosts that look like undisturbed galaxies. But the important thing is that we have wonderfully clear pictures to argue about. Quasar theories were mostly pure speculation before we had Hubble." The history of the elements Astronomers at the Hamburger Sternwarte use the Faint Object Spectrograph to analyse ultraviolet light from distant quasars, which they also examine by visible light from the ground. They trace the origin, through cosmic time, of elements like carbon, silicon and iron, from which planets and living things can be built. On its way to Hubble, the quasar light passes through various intervening galaxies and gas clouds, like the skewer of a kebab. Each object visited absorbs some of the quasar light, depending on the local abundances of the elements. As they detect more and more objects, Dieter Reimers and his colleagues form an impression of galaxies building up their stocks of elements progressively through time, by the alchemy of successive generations of stars. Apart from primordial hydrogen the second lightest element, helium, has also been abundant since the origin of the Universe. The first major discovery after Hubble's last refurbishment came from Peter Jakobsen of ESA's Space Science Department at Noordwijk, who detected ionized helium in the remote Universe, by the light of a very distant quasar, 0302-003. That was in January 1994, and since then Jakobsen has looked for the ionized helium using other quasars. He now suspects that this helium is nearly all gathered in clumps, rather than scattered freely through intergalactic space. If so, it greatly increases the estimates of the total mass of ordinary matter in the Universe. Through a lens to the early Universe Natural lenses scattered through the cosmos reveal distant galaxies, and make an astronomical tool for Richard Ellis of the Institute of Astronomy, Cambridge (UK). The strong gravity of an intervening cluster of galaxies can bend the light from more distant objects, so magnifying and intensifying their images. In one spectacular case, cluster Abell 2218 creates in Hubble's WFPC2 camera more than a hundred images of galaxies lying beyond it. Without the magnifying effect of the cluster, many of these remote objects would be too faint to study in detail. Compared with man-made optics, the gravitational lenses are complex. They produce multiple images (as many as seven or more views of the same object) and they also smear the images into arcs. Team-member Jean-Paul Kneib, who is now at Toulouse, uses the distortions as a guide to distance. The more distorted the image, the farther off a galaxy is. The galaxies imaged by Abell 2218 are 5 to 8 billion light-years away, and Kneib's estimates have been confirmed by Tim Ebbels of Cambridge using the William Herschel Telescope located on the Spanish island of La Palma. Seen as they were early in the history of the Universe, the objects seem surprisingly similar to nearer and more mature galaxies. The cosmic scale Gustav Tammann of Basel and his collaborators use the Hubble Space Telescope to measure the Hubble Constant. Both are named after Edwin Hubble who discovered, almost 70 years ago, that the galaxies are spreading apart. The Hubble Constant is the rate of expansion -- and the most important number in cosmology, because it fixes the size and the maximum age of the observable Universe. Since the launch of the space telescope in 1990, two independent teams have tried to fix the constant but their answers disagree. A high expansion rate, which makes the Universe relatively young, is preferred by Wendy Freedman's team consisting largely of American astronomers. A lower value for Hubble's Constant, implying an older Universe, comes from a mainly European team led by the American astronomer Allan Sandage. Tammann belongs to the latter, "old Universe" camp and he is philosophical about the delay in reaching a consensus. "I've been waiting nearly 20 years for this result, and I expect the arguments will go on for a while longer," Gustav Tammann says. "In 1979 I asserted that a key task for the space telescope should be to use variable stars to fix the distances to nearby galaxies in which standard supernovae have been seen. Then the supernovae become candles lighting our way far out into the Universe. Well we've done it now, with stars in seven galaxies, and their supernovae give us wonderfully consistent answers. So we're in no mood to compromise, or to split the difference with Wendy Freedman's Hubble Constant. Time will tell us who is closer to the right answer." * Note to TV editors : A betacam tape on this subject is available from ESA Public Relations Office (Tel: 33(0)01.53.69.7155 Fax : 33(0)01.53.69.7690)