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Sample records for algorithm resolves loops

  1. Wilson loops in warped resolved deformed conifolds

    SciTech Connect

    Bennett, Stephen

    2011-11-15

    We calculate quark-antiquark potentials using the relationship between the expectation value of the Wilson loop and the action of a probe string in the string dual. We review and categorise the possible forms of the dependence of the energy on the separation between the quarks. In particular, we examine the possibility of there being a minimum separation for probe strings which do not penetrate close to the origin of the bulk space, and derive a condition which determines whether this is the case. We then apply these considerations to the flavoured resolved deformed conifold background of Gaillard et al. (2010) . We suggest that the unusual behaviour that we observe in this solution is likely to be related to the IR singularity which is not present in the unflavoured case. - Highlights: > We calculate quark-antiquark potentials using the Wilson loop and the action of a probe string in the string dual. > We review and categorise the possible forms of the dependence of the energy on the separation between the quarks. > We look in particular at the flavoured resolved deformed conifold. > There appears to be unusual behaviour which seems likely to be related to the IR singularity introduced by flavours.

  2. Closed Loop System Identification with Genetic Algorithms

    NASA Technical Reports Server (NTRS)

    Whorton, Mark S.

    2004-01-01

    High performance control design for a flexible space structure is challenging since high fidelity plant models are di.cult to obtain a priori. Uncertainty in the control design models typically require a very robust, low performance control design which must be tuned on-orbit to achieve the required performance. Closed loop system identi.cation is often required to obtain a multivariable open loop plant model based on closed-loop response data. In order to provide an accurate initial plant model to guarantee convergence for standard local optimization methods, this paper presents a global parameter optimization method using genetic algorithms. A minimal representation of the state space dynamics is employed to mitigate the non-uniqueness and over-parameterization of general state space realizations. This control-relevant system identi.cation procedure stresses the joint nature of the system identi.cation and control design problem by seeking to obtain a model that minimizes the di.erence between the predicted and actual closed-loop performance.

  3. A hybrid genetic algorithm for resolving closely spaced objects

    NASA Technical Reports Server (NTRS)

    Abbott, R. J.; Lillo, W. E.; Schulenburg, N.

    1995-01-01

    A hybrid genetic algorithm is described for performing the difficult optimization task of resolving closely spaced objects appearing in space based and ground based surveillance data. This application of genetic algorithms is unusual in that it uses a powerful domain-specific operation as a genetic operator. Results of applying the algorithm to real data from telescopic observations of a star field are presented.

  4. A worm algorithm for the fully-packed loop model

    NASA Astrophysics Data System (ADS)

    Zhang, Wei; Garoni, Timothy M.; Deng, Youjin

    2009-06-01

    We present a Markov-chain Monte Carlo algorithm of worm type that correctly simulates the fully-packed loop model with n=1 on the honeycomb lattice, and we prove that it is ergodic and has uniform stationary distribution. The honeycomb-lattice fully-packed loop model with n=1 is equivalent to the zero-temperature triangular-lattice antiferromagnetic Ising model, which is fully frustrated and notoriously difficult to simulate. We test this worm algorithm numerically and estimate the dynamic exponent z=0.515(8). We also measure several static quantities of interest, including loop-length and face-size moments. It appears numerically that the face-size moments are governed by the magnetic dimension for percolation.

  5. Mapping nested loop algorithms into multidimensional systolic arrays

    SciTech Connect

    Lee, P.Z. ); Kedem, Z.M. )

    1990-01-01

    This paper is concerned with transforming depth p-nested for loop algorithms into q-dimensional systolic VLSI arrays where 1 {le} q {le} p {minus} 1. Previously there existed complete characterizations of correct transformations only for the cases when q = p {minus} 1 or q = 1. The authors fill in this gap by giving formal necessary and sufficient conditions for correct transformation of a p-nested loop algorithm into a q-dimensional systolic array for any q, 1 {le} q {le} p {minus} 1. They also provide practical methods to derive optimal or suboptimal systolic array implementations. They apply the techniques developed by us to the automatic design of special purpose and programmable systolic arrays. The author's results also contribute towards automatic compilation onto more general purpose programmable arrays. Synthesis of linear and planar systolic array implementations for a three-dimensional cube-graph algorithm and a reindexed Warshall-Floyd pathfinding algorithm is used to illustrate our method.

  6. Some Algorithms For Simulating Size-resolved Aerosol Dynamics Models

    NASA Astrophysics Data System (ADS)

    Debry, E.; Sportisse, B.

    The objective of this presentation is to show some algorithms used to solve aerosol dynamics in 3D dispersion models. INTRODUCTION The gas phase pollution has been widely studied and some models are now available . The situation is quite different with respect to atmospheric aerosols . However at- mospheric particulate matter significantly influences atmospheric properties such as radiative balance, cloud formation, gas pollutants concentrations ( gas to particle con- version ), and has an impact on man health. As aerosols properties ( optical, hygroscopic, noxiousness ) depend mainly on their size, it appears important to be able to follow the aerosol ( or particle ) size distribution (PSD) during time. This former is modified by physical processes as coagulation, condensation or evaporation, nucleation and removal. Aerosol dynamics is usually modelized by the well-known General Dynamics Equation (GDE) [1]. MODELS Several models already exist to solve this equation. Multi-modal models are widely used [2] [3] because of the few parameters needed, but the GDE is solved only on its moments and the PSD is assumed to remain in a log-normal form. On the contrary, size-resolved models implies a discretization of the aerosol size spec- trum into several bins and to solve the GDE within each one. This step can be per- formed either by resolving each process separately ( splitting ), for example coagula- tion can be resolved by the well-known "size-binning" algorithms [4] and condensa- tion leads to an advection equation on the PSD [5], or by coupling all processes, what the finite elements [6] and stochastic methods [7] allows. Stochastic algorithms may not be competitive compared to deterministic ones with respect to the computation time, but they provide reference solutions useful to validate more operational codes on realistic cases, as analytic solutions of the GDE exist only for academic cases. REFERENCES [1] Seinfeld, J.H. and Pandis,S.N. Atmospheric chemistry and

  7. RESOLVE: A new algorithm for aperture synthesis imaging of extended emission in radio astronomy

    NASA Astrophysics Data System (ADS)

    Junklewitz, H.; Bell, M. R.; Selig, M.; Enßlin, T. A.

    2016-02-01

    We present resolve, a new algorithm for radio aperture synthesis imaging of extended and diffuse emission in total intensity. The algorithm is derived using Bayesian statistical inference techniques, estimating the surface brightness in the sky assuming a priori log-normal statistics. resolve estimates the measured sky brightness in total intensity, and the spatial correlation structure in the sky, which is used to guide the algorithm to an optimal reconstruction of extended and diffuse sources. During this process, the algorithm succeeds in deconvolving the effects of the radio interferometric point spread function. Additionally, resolve provides a map with an uncertainty estimate of the reconstructed surface brightness. Furthermore, with resolve we introduce a new, optimal visibility weighting scheme that can be viewed as an extension to robust weighting. In tests using simulated observations, the algorithm shows improved performance against two standard imaging approaches for extended sources, Multiscale-CLEAN and the Maximum Entropy Method.

  8. A component-level failure detection and identification algorithm based on open-loop and closed-loop state estimators

    NASA Astrophysics Data System (ADS)

    You, Seung-Han; Cho, Young Man; Hahn, Jin-Oh

    2013-04-01

    This study presents a component-level failure detection and identification (FDI) algorithm for a cascade mechanical system subsuming a plant driven by an actuator unit. The novelty of the FDI algorithm presented in this study is that it is able to discriminate failure occurring in the actuator unit, the sensor measuring the output of the actuator unit, and the plant driven by the actuator unit. The proposed FDI algorithm exploits the measurement of the actuator unit output together with its estimates generated by open-loop (OL) and closed-loop (CL) estimators to enable FDI at the component's level. In this study, the OL estimator is designed based on the system identification of the actuator unit. The CL estimator, which is guaranteed to be stable against variations in the plant, is synthesized based on the dynamics of the entire cascade system. The viability of the proposed algorithm is demonstrated using a hardware-in-the-loop simulation (HILS), which shows that it can detect and identify target failures reliably in the presence of plant uncertainties.

  9. The solar extreme ultra-violet corona: Resolved loops and the unresolved active region corona

    NASA Astrophysics Data System (ADS)

    Cirtain, Jonathan Wesley

    In this work, physical characteristics of the solar corona as observed in the Extreme Ultra-Violet (EUV) regime are investigated. The focus will be the regions of intense EUV radiation generally found near the locations of sunspots. These regions are commonly called active regions. Multiple space- based observing platforms have been deployed in the last decade; it is possible to use several of these observatories in combination to develop a more complete picture of the solar corona. Joint Observing Program 146 was created to collect spectroscopic intensities using the Coronal Diagnostic Spectrometer on Solar and Heliospheric Observatory and EUV images using NASA's Transition Region and Coronal Explorer. The emission line intensities are analyzed to develop an understanding of the temperature and density of the active region coronal plasma. However, the performance of the CDS instrument in the spatial and temporal domains is limited and to compensate for these limitations, data collected by the TRACE instrument provide a high spatial and temporal resolution set of observations. One of the most exciting unsolved problems in solar astrophysics is to understand why the corona maintains a temperature roughly two orders of magnitude higher than the underlying material. A detailed investigation of the coronal emission has provided constraints on models of the heating mechanism, since the temperature, density and evolution of emission rates for multiple ionic species are indicative of the mechanism(s) working to heat the corona. The corona appears to consist of multiple unresolved structures as well as resolved active region structures, called coronal loops. The purpose of the present work is to determine the characteristics of the unresolved background corona. Using the characterizations of the coronal unresolved background, results for loops after background subtraction are also presented. This work demonstrates the magnitude of the unresolved coronal emission with

  10. A genetic algorithm based molecular modeling technique for RNA stem-loop structures.

    PubMed Central

    Ogata, H; Akiyama, Y; Kanehisa, M

    1995-01-01

    A new modeling technique for arriving at the three dimensional (3-D) structure of an RNA stem-loop has been developed based on a conformational search by a genetic algorithm and the following refinement by energy minimization. The genetic algorithm simultaneously optimizes a population of conformations in the predefined conformational space and generates 3-D models of RNA. The fitness function to be optimized by the algorithm has been defined to reflect the satisfaction of known conformational constraints. In addition to a term for distance constraints, the fitness function contains a term to constrain each local conformation near to a prepared template conformation. The technique has been applied to the two loops of tRNA, the anticodon loop and the T-loop, and has found good models with small root mean square deviations from the crystal structure. Slightly different models have also been found for the anticodon loop. The analysis of a collection of alternative models obtained has revealed statistical features of local variations at each base position. Images PMID:7533901

  11. Phase Reconstruction from FROG Using Genetic Algorithms[Frequency-Resolved Optical Gating

    SciTech Connect

    Omenetto, F.G.; Nicholson, J.W.; Funk, D.J.; Taylor, A.J.

    1999-04-12

    The authors describe a new technique for obtaining the phase and electric field from FROG measurements using genetic algorithms. Frequency-Resolved Optical Gating (FROG) has gained prominence as a technique for characterizing ultrashort pulses. FROG consists of a spectrally resolved autocorrelation of the pulse to be measured. Typically a combination of iterative algorithms is used, applying constraints from experimental data, and alternating between the time and frequency domain, in order to retrieve an optical pulse. The authors have developed a new approach to retrieving the intensity and phase from FROG data using a genetic algorithm (GA). A GA is a general parallel search technique that operates on a population of potential solutions simultaneously. Operators in a genetic algorithm, such as crossover, selection, and mutation are based on ideas taken from evolution.

  12. A combined NLP-differential evolution algorithm approach for the optimization of looped water distribution systems

    NASA Astrophysics Data System (ADS)

    Zheng, Feifei; Simpson, Angus R.; Zecchin, Aaron C.

    2011-08-01

    This paper proposes a novel optimization approach for the least cost design of looped water distribution systems (WDSs). Three distinct steps are involved in the proposed optimization approach. In the first step, the shortest-distance tree within the looped network is identified using the Dijkstra graph theory algorithm, for which an extension is proposed to find the shortest-distance tree for multisource WDSs. In the second step, a nonlinear programming (NLP) solver is employed to optimize the pipe diameters for the shortest-distance tree (chords of the shortest-distance tree are allocated the minimum allowable pipe sizes). Finally, in the third step, the original looped water network is optimized using a differential evolution (DE) algorithm seeded with diameters in the proximity of the continuous pipe sizes obtained in step two. As such, the proposed optimization approach combines the traditional deterministic optimization technique of NLP with the emerging evolutionary algorithm DE via the proposed network decomposition. The proposed methodology has been tested on four looped WDSs with the number of decision variables ranging from 21 to 454. Results obtained show the proposed approach is able to find optimal solutions with significantly less computational effort than other optimization techniques.

  13. A self-adaptive genetic algorithm to estimate JA model parameters considering minor loops

    NASA Astrophysics Data System (ADS)

    Lu, Hai-liang; Wen, Xi-shan; Lan, Lei; An, Yun-zhu; Li, Xiao-ping

    2015-01-01

    A self-adaptive genetic algorithm for estimating Jiles-Atherton (JA) magnetic hysteresis model parameters is presented. The fitness function is established based on the distances between equidistant key points of normalized hysteresis loops. Linearity function and logarithm function are both adopted to code the five parameters of JA model. Roulette wheel selection is used and the selection pressure is adjusted adaptively by deducting a proportional which depends on current generation common value. The Crossover operator is established by combining arithmetic crossover and multipoint crossover. Nonuniform mutation is improved by adjusting the mutation ratio adaptively. The algorithm is used to estimate the parameters of one kind of silicon-steel sheet's hysteresis loops, and the results are in good agreement with published data.

  14. Loop closure detection by algorithmic information theory: implemented on range and camera image data.

    PubMed

    Ravari, Alireza Norouzzadeh; Taghirad, Hamid D

    2014-10-01

    In this paper the problem of loop closing from depth or camera image information in an unknown environment is investigated. A sparse model is constructed from a parametric dictionary for every range or camera image as mobile robot observations. In contrast to high-dimensional feature-based representations, in this model, the dimension of the sensor measurements' representations is reduced. Considering the loop closure detection as a clustering problem in high-dimensional space, little attention has been paid to the curse of dimensionality in the existing state-of-the-art algorithms. In this paper, a representation is developed from a sparse model of images, with a lower dimension than original sensor observations. Exploiting the algorithmic information theory, the representation is developed such that it has the geometrically transformation invariant property in the sense of Kolmogorov complexity. A universal normalized metric is used for comparison of complexity based representations of image models. Finally, a distinctive property of normalized compression distance is exploited for detecting similar places and rejecting incorrect loop closure candidates. Experimental results show efficiency and accuracy of the proposed method in comparison to the state-of-the-art algorithms and some recently proposed methods. PMID:24968363

  15. A robust model predictive control algorithm for uncertain nonlinear systems that guarantees resolvability

    NASA Technical Reports Server (NTRS)

    Acikmese, Ahmet Behcet; Carson, John M., III

    2006-01-01

    A robustly stabilizing MPC (model predictive control) algorithm for uncertain nonlinear systems is developed that guarantees resolvability. With resolvability, initial feasibility of the finite-horizon optimal control problem implies future feasibility in a receding-horizon framework. The control consists of two components; (i) feed-forward, and (ii) feedback part. Feed-forward control is obtained by online solution of a finite-horizon optimal control problem for the nominal system dynamics. The feedback control policy is designed off-line based on a bound on the uncertainty in the system model. The entire controller is shown to be robustly stabilizing with a region of attraction composed of initial states for which the finite-horizon optimal control problem is feasible. The controller design for this algorithm is demonstrated on a class of systems with uncertain nonlinear terms that have norm-bounded derivatives and derivatives in polytopes. An illustrative numerical example is also provided.

  16. Design and analysis of closed-loop decoder adaptation algorithms for brain-machine interfaces.

    PubMed

    Dangi, Siddharth; Orsborn, Amy L; Moorman, Helene G; Carmena, Jose M

    2013-07-01

    Closed-loop decoder adaptation (CLDA) is an emerging paradigm for achieving rapid performance improvements in online brain-machine interface (BMI) operation. Designing an effective CLDA algorithm requires making multiple important decisions, including choosing the timescale of adaptation, selecting which decoder parameters to adapt, crafting the corresponding update rules, and designing CLDA parameters. These design choices, combined with the specific settings of CLDA parameters, will directly affect the algorithm's ability to make decoder parameters converge to values that optimize performance. In this article, we present a general framework for the design and analysis of CLDA algorithms and support our results with experimental data of two monkeys performing a BMI task. First, we analyze and compare existing CLDA algorithms to highlight the importance of four critical design elements: the adaptation timescale, selective parameter adaptation, smooth decoder updates, and intuitive CLDA parameters. Second, we introduce mathematical convergence analysis using measures such as mean-squared error and KL divergence as a useful paradigm for evaluating the convergence properties of a prototype CLDA algorithm before experimental testing. By applying these measures to an existing CLDA algorithm, we demonstrate that our convergence analysis is an effective analytical tool that can ultimately inform and improve the design of CLDA algorithms. PMID:23607558

  17. Learning tensegrity locomotion using open-loop control signals and coevolutionary algorithms.

    PubMed

    Iscen, Atil; Caluwaerts, Ken; Bruce, Jonathan; Agogino, Adrian; SunSpiral, Vytas; Tumer, Kagan

    2015-01-01

    Soft robots offer many advantages over traditional rigid robots. However, soft robots can be difficult to control with standard control methods. Fortunately, evolutionary algorithms can offer an elegant solution to this problem. Instead of creating controls to handle the intricate dynamics of these robots, we can simply evolve the controls using a simulation to provide an evaluation function. In this article, we show how such a control paradigm can be applied to an emerging field within soft robotics: robots based on tensegrity structures. We take the model of the Spherical Underactuated Planetary Exploration Robot ball (SUPERball), an icosahedron tensegrity robot under production at NASA Ames Research Center, develop a rolling locomotion algorithm, and study the learned behavior using an accurate model of the SUPERball simulated in the NASA Tensegrity Robotics Toolkit. We first present the historical-average fitness-shaping algorithm for coevolutionary algorithms to speed up learning while favoring robustness over optimality. Second, we use a distributed control approach by coevolving open-loop control signals for each controller. Being simple and distributed, open-loop controllers can be readily implemented on SUPERball hardware without the need for sensor information or precise coordination. We analyze signals of different complexities and frequencies. Among the learned policies, we take one of the best and use it to analyze different aspects of the rolling gait, such as lengths, tensions, and energy consumption. We also discuss the correlation between the signals controlling different parts of the tensegrity robot. PMID:25951199

  18. Algorithms for a Closed-Loop Artificial Pancreas: The Case for Model Predictive Control

    PubMed Central

    Bequette, B. Wayne

    2013-01-01

    The relative merits of model predictive control (MPC) and proportional-integral-derivative (PID) control are discussed, with the end goal of a closed-loop artificial pancreas (AP). It is stressed that neither MPC nor PID are single algorithms, but rather are approaches or strategies that may be implemented very differently by different engineers. The primary advantages to MPC are that (i) constraints on the insulin delivery rate (and/or insulin on board) can be explicitly included in the control calculation; (ii) it is a general framework that makes it relatively easy to include the effect of meals, exercise, and other events that are a function of the time of day; and (iii) it is flexible enough to include many different objectives, from set-point tracking (target) to zone (control to range). In the end, however, it is recognized that the control algorithm, while important, represents only a portion of the effort required to develop a closed-loop AP. Thus, any number of algorithms/approaches can be successful—the engineers involved in the design must have experience with the particular technique, including the important experience of implementing the algorithm in human studies and not simply through simulation studies. PMID:24351190

  19. Deterministic and stochastic algorithms for resolving the flow fields in ducts and networks using energy minimization

    NASA Astrophysics Data System (ADS)

    Sochi, Taha

    2016-09-01

    Several deterministic and stochastic multi-variable global optimization algorithms (Conjugate Gradient, Nelder-Mead, Quasi-Newton and global) are investigated in conjunction with energy minimization principle to resolve the pressure and volumetric flow rate fields in single ducts and networks of interconnected ducts. The algorithms are tested with seven types of fluid: Newtonian, power law, Bingham, Herschel-Bulkley, Ellis, Ree-Eyring and Casson. The results obtained from all those algorithms for all these types of fluid agree very well with the analytically derived solutions as obtained from the traditional methods which are based on the conservation principles and fluid constitutive relations. The results confirm and generalize the findings of our previous investigations that the energy minimization principle is at the heart of the flow dynamics systems. The investigation also enriches the methods of computational fluid dynamics for solving the flow fields in tubes and networks for various types of Newtonian and non-Newtonian fluids.

  20. The indexing ambiguity in serial femtosecond crystallography (SFX) resolved using an expectation maximization algorithm

    PubMed Central

    Liu, Haiguang; Spence, John C.H.

    2014-01-01

    Crystallographic auto-indexing algorithms provide crystal orientations and unit-cell parameters and assign Miller indices based on the geometric relations between the Bragg peaks observed in diffraction patterns. However, if the Bravais symmetry is higher than the space-group symmetry, there will be multiple indexing options that are geometrically equivalent, and hence many ways to merge diffraction intensities from protein nanocrystals. Structure factor magnitudes from full reflections are required to resolve this ambiguity but only partial reflections are available from each XFEL shot, which must be merged to obtain full reflections from these ‘stills’. To resolve this chicken-and-egg problem, an expectation maximization algorithm is described that iteratively constructs a model from the intensities recorded in the diffraction patterns as the indexing ambiguity is being resolved. The reconstructed model is then used to guide the resolution of the indexing ambiguity as feedback for the next iteration. Using both simulated and experimental data collected at an X-ray laser for photosystem I in the P63 space group (which supports a merohedral twinning indexing ambiguity), the method is validated. PMID:25485120

  1. Development of a prototype algorithm for the operational retrieval of height-resolved products from GOME

    NASA Technical Reports Server (NTRS)

    Spurr, Robert J. D.

    1997-01-01

    Global ozone monitoring experiment (GOME) level 2 products of total ozone column amounts have been generated on a routine operational basis since July 1996. These products and the level 1 radiance products are the major outputs from the ERS-2 ground segment GOME data processor (GDP) at DLR in Germany. Off-line scientific work has already shown the feasibility of ozone profile retrieval from GOME. It is demonstrated how the retrievals can be performed in an operational context. Height-resolved retrieval is based on the optimal estimation technique, #and cloud-contaminated scenes are treated in an equivalent reflecting surface approximation. The prototype must be able to handle GOME measurements routinely on a global basis. Requirements for the major components of the algorithm are described: this incorporates an overall strategy for operational height-resolved retrieval from GOME.

  2. Battery algorithm verification and development using hardware-in-the-loop testing

    NASA Astrophysics Data System (ADS)

    He, Yongsheng; Liu, Wei; Koch, Brain J.

    Battery algorithms play a vital role in hybrid electric vehicles (HEVs), plug-in hybrid electric vehicles (PHEVs), extended-range electric vehicles (EREVs), and electric vehicles (EVs). The energy management of hybrid and electric propulsion systems needs to rely on accurate information on the state of the battery in order to determine the optimal electric drive without abusing the battery. In this study, a cell-level hardware-in-the-loop (HIL) system is used to verify and develop state of charge (SOC) and power capability predictions of embedded battery algorithms for various vehicle applications. Two different batteries were selected as representative examples to illustrate the battery algorithm verification and development procedure. One is a lithium-ion battery with a conventional metal oxide cathode, which is a power battery for HEV applications. The other is a lithium-ion battery with an iron phosphate (LiFePO 4) cathode, which is an energy battery for applications in PHEVs, EREVs, and EVs. The battery cell HIL testing provided valuable data and critical guidance to evaluate the accuracy of the developed battery algorithms, to accelerate battery algorithm future development and improvement, and to reduce hybrid/electric vehicle system development time and costs.

  3. Closed loop, DM diversity-based, wavefront correction algorithm for high contrast imaging systems.

    PubMed

    Give'on, Amir; Belikov, Ruslan; Shaklan, Stuart; Kasdin, Jeremy

    2007-09-17

    High contrast imaging from space relies on coronagraphs to limit diffraction and a wavefront control systems to compensate for imperfections in both the telescope optics and the coronagraph. The extreme contrast required (up to 10(-10) for terrestrial planets) puts severe requirements on the wavefront control system, as the achievable contrast is limited by the quality of the wavefront. This paper presents a general closed loop correction algorithm for high contrast imaging coronagraphs by minimizing the energy in a predefined region in the image where terrestrial planets could be found. The estimation part of the algorithm reconstructs the complex field in the image plane using phase diversity caused by the deformable mirror. This method has been shown to achieve faster and better correction than classical speckle nulling. PMID:19547602

  4. Small Body GN&C Research Report: A Robust Model Predictive Control Algorithm with Guaranteed Resolvability

    NASA Technical Reports Server (NTRS)

    Acikmese, Behcet A.; Carson, John M., III

    2005-01-01

    A robustly stabilizing MPC (model predictive control) algorithm for uncertain nonlinear systems is developed that guarantees the resolvability of the associated finite-horizon optimal control problem in a receding-horizon implementation. The control consists of two components; (i) feedforward, and (ii) feedback part. Feed-forward control is obtained by online solution of a finite-horizon optimal control problem for the nominal system dynamics. The feedback control policy is designed off-line based on a bound on the uncertainty in the system model. The entire controller is shown to be robustly stabilizing with a region of attraction composed of initial states for which the finite-horizon optimal control problem is feasible. The controller design for this algorithm is demonstrated on a class of systems with uncertain nonlinear terms that have norm-bounded derivatives, and derivatives in polytopes. An illustrative numerical example is also provided.

  5. Limitations of Time-Resolved Fluorescence Suggested by Molecular Simulations: Assessing the Dynamics of T cell Receptor Binding Loops

    PubMed Central

    Scott, Daniel R.; Vardeman, Charles F.; Corcelli, Steven A.; Baker, Brian M.

    2012-01-01

    Time-resolved fluorescence anisotropy (TRFA) has a rich history in evaluating protein dynamics. Yet as often employed, TRFA assumes that the motional properties of a covalently tethered fluorescent probe accurately portray the motional properties of the protein backbone at the probe attachment site. In an extensive survey using TRFA to study the dynamics of the binding loops of a αβ T cell receptor, we observed multiple discrepancies between the TRFA data and previously published results that led us to question this assumption. We thus simulated several of the experimentally probed systems using a protocol that permitted accurate determination of probe and protein time correlation functions. We found excellent agreement in the decays of the experimental and simulated correlation functions. However, the motional properties of the probe were poorly correlated with those of the backbone of both the labeled and unlabeled protein. Our results warrant caution in the interpretation of TRFA data and suggest further studies to ascertain the extent to which probe dynamics reflect those of the protein backbone. Meanwhile, the agreement between experiment and computation validates the use of molecular dynamics simulations as an accurate tool for exploring the molecular motion of T cell receptors and their binding loops. PMID:23260055

  6. Design and hardware-in-loop implementation of collision avoidance algorithms for heavy commercial road vehicles

    NASA Astrophysics Data System (ADS)

    Rajaram, Vignesh; Subramanian, Shankar C.

    2016-07-01

    An important aspect from the perspective of operational safety of heavy road vehicles is the detection and avoidance of collisions, particularly at high speeds. The development of a collision avoidance system is the overall focus of the research presented in this paper. The collision avoidance algorithm was developed using a sliding mode controller (SMC) and compared to one developed using linear full state feedback in terms of performance and controller effort. Important dynamic characteristics such as load transfer during braking, tyre-road interaction, dynamic brake force distribution and pneumatic brake system response were considered. The effect of aerodynamic drag on the controller performance was also studied. The developed control algorithms have been implemented on a Hardware-in-Loop experimental set-up equipped with the vehicle dynamic simulation software, IPG/TruckMaker®. The evaluation has been performed for realistic traffic scenarios with different loading and road conditions. The Hardware-in-Loop experimental results showed that the SMC and full state feedback controller were able to prevent the collision. However, when the discrepancies in the form of parametric variations were included, the SMC provided better results in terms of reduced stopping distance and lower controller effort compared to the full state feedback controller.

  7. Synthetic line-of-sight algorithms for hardware-in-the-loop simulations

    NASA Astrophysics Data System (ADS)

    Richard, Henri; Lowman, Alan; Ballard, Gary

    2005-05-01

    During the flight of guided submunitions, translation of the missile with respect to the designated aimpoint causes a rotation of the Line-of-Sight (LOS) in inertial space. Large transmit arrays or 5 axis CARCO tables are used to perform True LOS (TLOS) for in-band simulations. Both of these TLOS approaches have cost or fidelity issues for RF seekers. Typically RF Hardware-in-the-Loop (HWIL) simulations of these guided submunitions are mounted on a Three Axes Rotational Flight Simulator (TARFS), which is not capable of translation, and utilize a 2 to 3 seeker beam width transmit array. This necessitates using a Synthetic Line-of-Sight (SLOS) algorithm with the TARFS in order to maintain the proper line-of-sight orientation during all phases of flight which typically includes largely varying LOS motion. This paper presents a simple explanation depicting TLOS and SLOS (TARFS) geometry and the seamless boresight/target SLOS algorithm utilized in AMRDEC's RF4 facility for a test article flight profile. In conclusion this paper will summarize the current state of SLOS algorithms utilized at AMRDEC and challenges and possible solutions envisioned in the near future.

  8. Pre-Hardware Optimization and Implementation Of Fast Optics Closed Control Loop Algorithms

    NASA Technical Reports Server (NTRS)

    Kizhner, Semion; Lyon, Richard G.; Herman, Jay R.; Abuhassan, Nader

    2004-01-01

    One of the main heritage tools used in scientific and engineering data spectrum analysis is the Fourier Integral Transform and its high performance digital equivalent - the Fast Fourier Transform (FFT). The FFT is particularly useful in two-dimensional (2-D) image processing (FFT2) within optical systems control. However, timing constraints of a fast optics closed control loop would require a supercomputer to run the software implementation of the FFT2 and its inverse, as well as other image processing representative algorithm, such as numerical image folding and fringe feature extraction. A laboratory supercomputer is not always available even for ground operations and is not feasible for a night project. However, the computationally intensive algorithms still warrant alternative implementation using reconfigurable computing technologies (RC) such as Digital Signal Processors (DSP) and Field Programmable Gate Arrays (FPGA), which provide low cost compact super-computing capabilities. We present a new RC hardware implementation and utilization architecture that significantly reduces the computational complexity of a few basic image-processing algorithm, such as FFT2, image folding and phase diversity for the NASA Solar Viewing Interferometer Prototype (SVIP) using a cluster of DSPs and FPGAs. The DSP cluster utilization architecture also assures avoidance of a single point of failure, while using commercially available hardware. This, combined with the control algorithms pre-hardware optimization, or the first time allows construction of image-based 800 Hertz (Hz) optics closed control loops on-board a spacecraft, based on the SVIP ground instrument. That spacecraft is the proposed Earth Atmosphere Solar Occultation Imager (EASI) to study greenhouse gases CO2, C2H, H2O, O3, O2, N2O from Lagrange-2 point in space. This paper provides an advanced insight into a new type of science capabilities for future space exploration missions based on on-board image processing

  9. Linear-scaling source-sink algorithm for simulating time-resolved quantum transport and superconductivity

    NASA Astrophysics Data System (ADS)

    Weston, Joseph; Waintal, Xavier

    2016-04-01

    We report on a "source-sink" algorithm which allows one to calculate time-resolved physical quantities from a general nanoelectronic quantum system (described by an arbitrary time-dependent quadratic Hamiltonian) connected to infinite electrodes. Although mathematically equivalent to the nonequilibrium Green's function formalism, the approach is based on the scattering wave functions of the system. It amounts to solving a set of generalized Schrödinger equations that include an additional "source" term (coming from the time-dependent perturbation) and an absorbing "sink" term (the electrodes). The algorithm execution time scales linearly with both system size and simulation time, allowing one to simulate large systems (currently around 106 degrees of freedom) and/or large times (currently around 105 times the smallest time scale of the system). As an application we calculate the current-voltage characteristics of a Josephson junction for both short and long junctions, and recover the multiple Andreev reflection physics. We also discuss two intrinsically time-dependent situations: the relaxation time of a Josephson junction after a quench of the voltage bias, and the propagation of voltage pulses through a Josephson junction. In the case of a ballistic, long Josephson junction, we predict that a fast voltage pulse creates an oscillatory current whose frequency is controlled by the Thouless energy of the normal part. A similar effect is found for short junctions; a voltage pulse produces an oscillating current which, in the absence of electromagnetic environment, does not relax.

  10. A Real-Time and Closed-Loop Control Algorithm for Cascaded Multilevel Inverter Based on Artificial Neural Network

    PubMed Central

    Wang, Libing; Mao, Chengxiong; Wang, Dan; Lu, Jiming; Zhang, Junfeng; Chen, Xun

    2014-01-01

    In order to control the cascaded H-bridges (CHB) converter with staircase modulation strategy in a real-time manner, a real-time and closed-loop control algorithm based on artificial neural network (ANN) for three-phase CHB converter is proposed in this paper. It costs little computation time and memory. It has two steps. In the first step, hierarchical particle swarm optimizer with time-varying acceleration coefficient (HPSO-TVAC) algorithm is employed to minimize the total harmonic distortion (THD) and generate the optimal switching angles offline. In the second step, part of optimal switching angles are used to train an ANN and the well-designed ANN can generate optimal switching angles in a real-time manner. Compared with previous real-time algorithm, the proposed algorithm is suitable for a wider range of modulation index and results in a smaller THD and a lower calculation time. Furthermore, the well-designed ANN is embedded into a closed-loop control algorithm for CHB converter with variable direct voltage (DC) sources. Simulation results demonstrate that the proposed closed-loop control algorithm is able to quickly stabilize load voltage and minimize the line current's THD (<5%) when subjecting the DC sources disturbance or load disturbance. In real design stage, a switching angle pulse generation scheme is proposed and experiment results verify its correctness. PMID:24772025

  11. A real-time pressure estimation algorithm for closed-loop combustion control

    NASA Astrophysics Data System (ADS)

    Al-Durra, Ahmed; Canova, Marcello; Yurkovich, Stephen

    2013-07-01

    The cylinder pressure is arguably the most important variable characterizing the combustion process in internal combustion engines. In light of the recent advances in combustion technologies and in engine control, the use of cylinder pressure is now frequently considered as a feedback signal for closed-loop combustion control algorithms. In order to generate an accurate pressure trace for real-time combustion control and diagnostics, the output of the in-cylinder pressure transducer must be conditioned with signal processing methods to mitigate the well-known issues of offset and noise. While several techniques have been proposed for processing the cylinder pressure signal with limited computational burden, most of the available methods still require one to apply low-pass filters or moving average windows in order to mitigate the noise. This ultimately limits the opportunity of exploiting the in-cylinder pressure feedback for a cycle-by-cycle control of the combustion process. To this extent, this paper presents an estimation algorithm that extracts the pressure signal from the in-cylinder sensor in real-time, allowing for estimating the 50% burn rate location and IMEP on a cycle-by-cycle basis. The proposed approach relies on a model-based estimation algorithm whose starting point is a crank-angle based engine combustion model that predicts the in-cylinder pressure from the definition of a burn rate function. Linear parameter varying (LPV) techniques are then used to expand the region of estimation to cover the engine operating map, as well as allowing for real-time cylinder estimation during transients. The estimator is tested on the experimental data collected on an engine dynamometer as well as on a high-fidelity engine simulator. The results obtained show the effectiveness of the estimator in reconstructing the cylinder pressure on a crank-angle basis and in rejecting measurement noise and modeling errors, with considerably low computation effort.

  12. Neural signal processing and closed-loop control algorithm design for an implanted neural recording and stimulation system.

    PubMed

    Hamilton, Lei; McConley, Marc; Angermueller, Kai; Goldberg, David; Corba, Massimiliano; Kim, Louis; Moran, James; Parks, Philip D; Sang Chin; Widge, Alik S; Dougherty, Darin D; Eskandar, Emad N

    2015-08-01

    A fully autonomous intracranial device is built to continually record neural activities in different parts of the brain, process these sampled signals, decode features that correlate to behaviors and neuropsychiatric states, and use these features to deliver brain stimulation in a closed-loop fashion. In this paper, we describe the sampling and stimulation aspects of such a device. We first describe the signal processing algorithms of two unsupervised spike sorting methods. Next, we describe the LFP time-frequency analysis and feature derivation from the two spike sorting methods. Spike sorting includes a novel approach to constructing a dictionary learning algorithm in a Compressed Sensing (CS) framework. We present a joint prediction scheme to determine the class of neural spikes in the dictionary learning framework; and, the second approach is a modified OSort algorithm which is implemented in a distributed system optimized for power efficiency. Furthermore, sorted spikes and time-frequency analysis of LFP signals can be used to generate derived features (including cross-frequency coupling, spike-field coupling). We then show how these derived features can be used in the design and development of novel decode and closed-loop control algorithms that are optimized to apply deep brain stimulation based on a patient's neuropsychiatric state. For the control algorithm, we define the state vector as representative of a patient's impulsivity, avoidance, inhibition, etc. Controller parameters are optimized to apply stimulation based on the state vector's current state as well as its historical values. The overall algorithm and software design for our implantable neural recording and stimulation system uses an innovative, adaptable, and reprogrammable architecture that enables advancement of the state-of-the-art in closed-loop neural control while also meeting the challenges of system power constraints and concurrent development with ongoing scientific research designed

  13. A Generic 1D Forward Modeling and Inversion Algorithm for TEM Sounding with an Arbitrary Horizontal Loop

    NASA Astrophysics Data System (ADS)

    Li, Zhanhui; Huang, Qinghua; Xie, Xingbing; Tang, Xingong; Chang, Liao

    2016-08-01

    We present a generic 1D forward modeling and inversion algorithm for transient electromagnetic (TEM) data with an arbitrary horizontal transmitting loop and receivers at any depth in a layered earth. Both the Hankel and sine transforms required in the forward algorithm are calculated using the filter method. The adjoint-equation method is used to derive the formulation of data sensitivity at any depth in non-permeable media. The inversion algorithm based on this forward modeling algorithm and sensitivity formulation is developed using the Gauss-Newton iteration method combined with the Tikhonov regularization. We propose a new data-weighting method to minimize the initial model dependence that enhances the convergence stability. On a laptop with a CPU of i7-5700HQ@3.5 GHz, the inversion iteration of a 200 layered input model with a single receiver takes only 0.34 s, while it increases to only 0.53 s for the data from four receivers at a same depth. For the case of four receivers at different depths, the inversion iteration runtime increases to 1.3 s. Modeling the data with an irregular loop and an equal-area square loop indicates that the effect of the loop geometry is significant at early times and vanishes gradually along the diffusion of TEM field. For a stratified earth, inversion of data from more than one receiver is useful in noise reducing to get a more credible layered earth. However, for a resistive layer shielded below a conductive layer, increasing the number of receivers on the ground does not have significant improvement in recovering the resistive layer. Even with a down-hole TEM sounding, the shielded resistive layer cannot be recovered if all receivers are above the shielded resistive layer. However, our modeling demonstrates remarkable improvement in detecting the resistive layer with receivers in or under this layer.

  14. A Generic 1D Forward Modeling and Inversion Algorithm for TEM Sounding with an Arbitrary Horizontal Loop

    NASA Astrophysics Data System (ADS)

    Li, Zhanhui; Huang, Qinghua; Xie, Xingbing; Tang, Xingong; Chang, Liao

    2016-07-01

    We present a generic 1D forward modeling and inversion algorithm for transient electromagnetic (TEM) data with an arbitrary horizontal transmitting loop and receivers at any depth in a layered earth. Both the Hankel and sine transforms required in the forward algorithm are calculated using the filter method. The adjoint-equation method is used to derive the formulation of data sensitivity at any depth in non-permeable media. The inversion algorithm based on this forward modeling algorithm and sensitivity formulation is developed using the Gauss-Newton iteration method combined with the Tikhonov regularization. We propose a new data-weighting method to minimize the initial model dependence that enhances the convergence stability. On a laptop with a CPU of i7-5700HQ@3.5 GHz, the inversion iteration of a 200 layered input model with a single receiver takes only 0.34 s, while it increases to only 0.53 s for the data from four receivers at a same depth. For the case of four receivers at different depths, the inversion iteration runtime increases to 1.3 s. Modeling the data with an irregular loop and an equal-area square loop indicates that the effect of the loop geometry is significant at early times and vanishes gradually along the diffusion of TEM field. For a stratified earth, inversion of data from more than one receiver is useful in noise reducing to get a more credible layered earth. However, for a resistive layer shielded below a conductive layer, increasing the number of receivers on the ground does not have significant improvement in recovering the resistive layer. Even with a down-hole TEM sounding, the shielded resistive layer cannot be recovered if all receivers are above the shielded resistive layer. However, our modeling demonstrates remarkable improvement in detecting the resistive layer with receivers in or under this layer.

  15. Open-loop control of SCExAO's MEMS deformable mirror using the Fast Iterative Algorithm: speckle control performances

    NASA Astrophysics Data System (ADS)

    Blain, Célia; Guyon, Olivier; Martinache, Frantz; Bradley, Colin; Clergeon, Christophe

    2012-07-01

    Micro-Electro-Mechanical Systems (MEMS) deformable mirrors (DMs) are widely utilized in astronomical Adaptive Optics (AO) instrumentation. High precision open-loop control of MEMS DMs has been achieved by developing a high accuracy DM model, the Fast Iterative Algorithm (FIA), a physics-based model allowing precise control of the DM shape. Accurate open-loop control is particularly critical for the wavefront control of High- Contrast Imaging (HCI) instruments to create a dark hole area free of most slow and quasi-static speckles which remain the limiting factor for direct detection and imaging of exoplanets. The Subaru Coronagraphic Extreme Adaptive Optics (SCExAO) system is one of these high contrast imaging instruments and uses a 1024-actuator MEMS deformable mirror (DM) both in closed-loop and open-loop. The DM is used to modulate speckles in order to distinguish (i) speckles due to static and slow-varying residual aberrations from (ii) speckles due to genuine structures, such as exoplanets. The FIA has been fully integrated into the SCExAO wavefront control software and we report the FIA’s performance for the control of speckles in the focal plane.

  16. Using an Improved SIFT Algorithm and Fuzzy Closed-Loop Control Strategy for Object Recognition in Cluttered Scenes

    PubMed Central

    Nie, Haitao; Long, Kehui; Ma, Jun; Yue, Dan; Liu, Jinguo

    2015-01-01

    Partial occlusions, large pose variations, and extreme ambient illumination conditions generally cause the performance degradation of object recognition systems. Therefore, this paper presents a novel approach for fast and robust object recognition in cluttered scenes based on an improved scale invariant feature transform (SIFT) algorithm and a fuzzy closed-loop control method. First, a fast SIFT algorithm is proposed by classifying SIFT features into several clusters based on several attributes computed from the sub-orientation histogram (SOH), in the feature matching phase only features that share nearly the same corresponding attributes are compared. Second, a feature matching step is performed following a prioritized order based on the scale factor, which is calculated between the object image and the target object image, guaranteeing robust feature matching. Finally, a fuzzy closed-loop control strategy is applied to increase the accuracy of the object recognition and is essential for autonomous object manipulation process. Compared to the original SIFT algorithm for object recognition, the result of the proposed method shows that the number of SIFT features extracted from an object has a significant increase, and the computing speed of the object recognition processes increases by more than 40%. The experimental results confirmed that the proposed method performs effectively and accurately in cluttered scenes. PMID:25714094

  17. A Method for Precision Closed-Loop Irrigation Using a Modified PID Control Algorithm

    NASA Astrophysics Data System (ADS)

    Goodchild, Martin; Kühn, Karl; Jenkins, Malcolm; Burek, Kazimierz; Dutton, Andrew

    2016-04-01

    The benefits of closed-loop irrigation control have been demonstrated in grower trials which show the potential for improved crop yields and resource usage. Managing water use by controlling irrigation in response to soil moisture changes to meet crop water demands is a popular approach but requires knowledge of closed-loop control practice. In theory, to obtain precise closed-loop control of a system it is necessary to characterise every component in the control loop to derive the appropriate controller parameters, i.e. proportional, integral & derivative (PID) parameters in a classic PID controller. In practice this is often difficult to achieve. Empirical methods are employed to estimate the PID parameters by observing how the system performs under open-loop conditions. In this paper we present a modified PID controller, with a constrained integral function, that delivers excellent regulation of soil moisture by supplying the appropriate amount of water to meet the needs of the plant during the diurnal cycle. Furthermore, the modified PID controller responds quickly to changes in environmental conditions, including rainfall events which can result in: controller windup, under-watering and plant stress conditions. The experimental work successfully demonstrates the functionality of a constrained integral PID controller that delivers robust and precise irrigation control. Coir substrate strawberry growing trial data is also presented illustrating soil moisture control and the ability to match water deliver to solar radiation.

  18. Depth-resolved analytical model and correction algorithm for photothermal optical coherence tomography

    PubMed Central

    Lapierre-Landry, Maryse; Tucker-Schwartz, Jason M.; Skala, Melissa C.

    2016-01-01

    Photothermal OCT (PT-OCT) is an emerging molecular imaging technique that occupies a spatial imaging regime between microscopy and whole body imaging. PT-OCT would benefit from a theoretical model to optimize imaging parameters and test image processing algorithms. We propose the first analytical PT-OCT model to replicate an experimental A-scan in homogeneous and layered samples. We also propose the PT-CLEAN algorithm to reduce phase-accumulation and shadowing, two artifacts found in PT-OCT images, and demonstrate it on phantoms and in vivo mouse tumors. PMID:27446693

  19. Spatially Resolved Spectroscopy of a Balmer-dominated Shock in the Cygnus Loop: An Extremely Thin Cosmic-Ray Precursor?

    NASA Astrophysics Data System (ADS)

    Katsuda, Satoru; Maeda, Keiichi; Ohira, Yutaka; Yatsu, Yoichi; Mori, Koji; Aoki, Wako; Morihana, Kumiko; Raymond, John C.; Ghavamian, Parviz; Lee, Jae-Joon; Shimoda, Jiro; Yamazaki, Ryo

    2016-03-01

    We present high-resolution long-slit spectroscopy of a Balmer-dominated shock in the northeastern limb of the Cygnus Loop with the Subaru high dispersion spectrograph. By setting the slit angle along the shock normal, we investigate variations of the flux and profile of the Hα line from preshock to postshock regions with a spatial resolution of ˜4 × 1015 cm. The Hα line profile can be represented by a narrow (28.9 ± 0.7 km s-1) Gaussian in a diffuse region ahead of the shock, i.e., a photoionization precursor, and narrow (33.1 ± 0.2 km s-1) plus broad (130-230 km s-1) Gaussians at the shock itself. We find that the width of the narrow component abruptly increases up to 33.1 ± 0.2 km s-1, or 38.8 ± 0.4 km s-1 if we eliminate projected emission originating from the photoionization precursor, in an unresolved thin layer (≲4 × 1015 cm at a distance of 540 pc) at the shock. We show that the sudden broadening can be best explained by heating via damping of Alfvén waves in a thin cosmic-ray (CR) precursor, although other possibilities are not fully ruled out. The thickness of the CR precursor in the Cygnus Loop (a soft gamma-ray emitter) is an order of magnitude thinner than that in Tycho’s Knot g (a hard gamma-ray emitter), which may be caused by the different energy distribution of accelerated particles between the two sources. In this context, systematic studies might reveal a positive correlation between the thickness of the CR precursor and the hardness of the CR energy distribution.

  20. A double-loop structure in the adaptive generalized predictive control algorithm for control of robot end-point contact force.

    PubMed

    Wen, Shuhuan; Zhu, Jinghai; Li, Xiaoli; Chen, Shengyong

    2014-09-01

    Robot force control is an essential issue in robotic intelligence. There is much high uncertainty when robot end-effector contacts with the environment. Because of the environment stiffness effects on the system of the robot end-effector contact with environment, the adaptive generalized predictive control algorithm based on quantitative feedback theory is designed for robot end-point contact force system. The controller of the internal loop is designed on the foundation of QFT to control the uncertainty of the system. An adaptive GPC algorithm is used to design external loop controller to improve the performance and the robustness of the system. Two closed loops used in the design approach realize the system׳s performance and improve the robustness. The simulation results show that the algorithm of the robot end-effector contacting force control system is effective. PMID:24973336

  1. Effective followership: A standardized algorithm to resolve clinical conflicts and improve teamwork.

    PubMed

    Sculli, Gary L; Fore, Amanda M; Sine, David M; Paull, Douglas E; Tschannen, Dana; Aebersold, Michelle; Seagull, F Jacob; Bagian, James P

    2015-01-01

    In healthcare, the sustained presence of hierarchy between team members has been cited as a common contributor to communication breakdowns. Hierarchy serves to accentuate either actual or perceived chains of command, which may result in team members failing to challenge decisions made by leaders, despite concerns about adverse patient outcomes. While other tools suggest improved communication, none focus specifically on communication skills for team followers, nor do they provide techniques to immediately challenge authority and escalate assertiveness at a given moment in real time. This article presents data that show one such strategy, called the Effective Followership Algorithm, offering statistically significant improvements in team communication across the professional continuum from students and residents to experienced clinicians. PMID:26227290

  2. Loop tuning with specification on gain and phase margins via modified second-order sliding mode control algorithm

    NASA Astrophysics Data System (ADS)

    Boiko, I. M.

    2012-01-01

    The modified second-order sliding mode algorithm is used for controller tuning. Namely, the modified suboptimal algorithm-based test (modified SOT) and non-parametric tuning rules for proportional-integral-derivative (PID) controllers are presented in this article. In the developed method of test and tuning, the idea of coordinated selection of the test parameters and the controller tuning parameters is introduced. The proposed approach allows for the formulation of simple non-parametric tuning rules for PID controllers that provide desired amplitude or phase margins exactly. In the modified SOT, the frequency of the self-excited oscillations can be generated equal to either the phase crossover frequency or the magnitude crossover frequency of the open-loop system frequency response (including a future PID controller) - depending on the tuning method choice. The first option will provide tuning with specification on gain margin, and the second option will ensure tuning with specification on phase margin. Tuning rules for a PID controller and simulation examples are provided.

  3. Computational solution of spike overlapping using data-based subtraction algorithms to resolve synchronous sympathetic nerve discharge

    PubMed Central

    Su, Chun-Kuei; Chiang, Chia-Hsun; Lee, Chia-Ming; Fan, Yu-Pei; Ho, Chiu-Ming; Shyu, Liang-Yu

    2013-01-01

    Sympathetic nerves conveying central commands to regulate visceral functions often display activities in synchronous bursts. To understand how individual fibers fire synchronously, we establish “oligofiber recording techniques” to record “several” nerve fiber activities simultaneously, using in vitro splanchnic sympathetic nerve–thoracic spinal cord preparations of neonatal rats as experimental models. While distinct spike potentials were easily recorded from collagenase-dissociated sympathetic fibers, a problem arising from synchronous nerve discharges is a higher incidence of complex waveforms resulted from spike overlapping. Because commercial softwares do not provide an explicit solution for spike overlapping, a series of custom-made LabVIEW programs incorporated with MATLAB scripts was therefore written for spike sorting. Spikes were represented as data points after waveform feature extraction and automatically grouped by k-means clustering followed by principal component analysis (PCA) to verify their waveform homogeneity. For dissimilar waveforms with exceeding Hotelling's T2 distances from the cluster centroids, a unique data-based subtraction algorithm (SA) was used to determine if they were the complex waveforms resulted from superimposing a spike pattern close to the cluster centroid with the other signals that could be observed in original recordings. In comparisons with commercial software, higher accuracy was achieved by analyses using our algorithms for the synthetic data that contained synchronous spiking and complex waveforms. Moreover, both T2-selected and SA-retrieved spikes were combined as unit activities. Quantitative analyses were performed to evaluate if unit activities truly originated from single fibers. We conclude that applications of our programs can help to resolve synchronous sympathetic nerve discharges (SND). PMID:24198782

  4. A hybrid multi-loop genetic-algorithm/simplex/spatial-grid method for locating the optimum orientation of an adsorbed protein on a solid surface

    NASA Astrophysics Data System (ADS)

    Wei, Tao; Mu, Shengjing; Nakano, Aiichiro; Shing, Katherine

    2009-05-01

    Atomistic simulation of protein adsorption on a solid surface in aqueous environment is computationally demanding, therefore the determination of preferred protein orientations on the solid surface usually serves as an initial step in simulation studies. We have developed a hybrid multi-loop genetic-algorithm/simplex/spatial-grid method to search for low adsorption-energy orientations of a protein molecule on a solid surface. In this method, the surface and the protein molecule are treated as rigid bodies, whereas the bulk fluid is represented by spatial grids. For each grid point, an effective interaction region in the surface is defined by a cutoff distance, and the possible interaction energy between an atom at the grid point and the surface is calculated and recorded in a database. In searching for the optimum position and orientation, the protein molecule is translated and rotated as a rigid body with the configuration obtained from a previous Molecular Dynamic simulation. The orientation-dependent protein-surface interaction energy is obtained using the generated database of grid energies. The hybrid search procedure consists of two interlinked loops. In the first loop A, a genetic algorithm (GA) is applied to identify promising regions for the global energy minimum and a local optimizer with the derivative-free Nelder-Mead simplex method is used to search for the lowest-energy orientation within the identified regions. In the second loop B, a new population for GA is generated and competitive solution from loop A is improved. Switching between the two loops is adaptively controlled by the use of similarity analysis. We test the method for lysozyme adsorption on a hydrophobic hydrogen-terminated silicon (110) surface in implicit water (i.e., a continuum distance-dependent dielectric constant). The results show that the hybrid search method has faster convergence and better solution accuracy compared with the conventional genetic algorithm.

  5. Use of a Closed-Loop Tracking Algorithm for Orientation Bias Determination of an S-Band Ground Station

    NASA Technical Reports Server (NTRS)

    Welch, Bryan W.; Schrage, Dean S.; Piasecki, Marie T.

    2015-01-01

    The Space Communications and Navigation (SCaN) Testbed project completed installation and checkout testing of a new S-Band ground station at the NASA Glenn Research Center in Cleveland, Ohio in 2015. As with all ground stations, a key alignment process must be conducted to obtain offset angles in azimuth (AZ) and elevation (EL). In telescopes with AZ-EL gimbals, this is normally done with a two-star alignment process, where telescope-based pointing vectors are derived from catalogued locations with the AZ-EL bias angles derived from the pointing vector difference. For an antenna, the process is complicated without an optical asset. For the present study, the solution was to utilize the gimbal control algorithms closed-loop tracking capability to acquire the peak received power signal automatically from two distinct NASA Tracking and Data Relay Satellite (TDRS) spacecraft, without a human making the pointing adjustments. Briefly, the TDRS satellite acts as a simulated optical source and the alignment process proceeds exactly the same way as a one-star alignment. The data reduction process, which will be discussed in the paper, results in two bias angles which are retained for future pointing determination. Finally, the paper compares the test results and provides lessons learned from the activity.

  6. Optimization of the Inverse Algorithm for Estimating the Optical Properties of Biological Materials Using Spatially-resolved Diffuse Reflectance Technique

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Determination of the optical properties from intact biological materials based on diffusion approximation theory is a complicated inverse problem, and it requires proper implementation of inverse algorithm, instrumentation, and experiment. This work was aimed at optimizing the procedure of estimatin...

  7. Hardware-In-The-Loop Testing of Continuous Control Algorithms for a Precision Formation Flying Demonstration Mission

    NASA Technical Reports Server (NTRS)

    Naasz, Bo J.; Burns, Richard D.; Gaylor, David; Higinbotham, John

    2004-01-01

    A sample mission sequence is defined for a low earth orbit demonstration of Precision Formation Flying (PFF). Various guidance navigation and control strategies are discussed for use in the PFF experiment phases. A sample PFF experiment is implemented and tested in a realistic Hardware-in-the-Loop (HWIL) simulation using the Formation Flying Test Bed (FFTB) at NASA's Goddard Space Flight Center.

  8. SU-E-J-85: Leave-One-Out Perturbation (LOOP) Fitting Algorithm for Absolute Dose Film Calibration

    SciTech Connect

    Chu, A; Ahmad, M; Chen, Z; Nath, R

    2014-06-01

    Purpose: To introduce an outliers-recognition fitting routine for film dosimetry. It cannot only be flexible with any linear and non-linear regression but also can provide information for the minimal number of sampling points, critical sampling distributions and evaluating analytical functions for absolute film-dose calibration. Methods: The technique, leave-one-out (LOO) cross validation, is often used for statistical analyses on model performance. We used LOO analyses with perturbed bootstrap fitting called leave-one-out perturbation (LOOP) for film-dose calibration . Given a threshold, the LOO process detects unfit points (“outliers”) compared to other cohorts, and a bootstrap fitting process follows to seek any possibilities of using perturbations for further improvement. After that outliers were reconfirmed by a traditional t-test statistics and eliminated, then another LOOP feedback resulted in the final. An over-sampled film-dose- calibration dataset was collected as a reference (dose range: 0-800cGy), and various simulated conditions for outliers and sampling distributions were derived from the reference. Comparisons over the various conditions were made, and the performance of fitting functions, polynomial and rational functions, were evaluated. Results: (1) LOOP can prove its sensitive outlier-recognition by its statistical correlation to an exceptional better goodness-of-fit as outliers being left-out. (2) With sufficient statistical information, the LOOP can correct outliers under some low-sampling conditions that other “robust fits”, e.g. Least Absolute Residuals, cannot. (3) Complete cross-validated analyses of LOOP indicate that the function of rational type demonstrates a much superior performance compared to the polynomial. Even with 5 data points including one outlier, using LOOP with rational function can restore more than a 95% value back to its reference values, while the polynomial fitting completely failed under the same conditions

  9. Validation and Development of a New Automatic Algorithm for Time-Resolved Segmentation of the Left Ventricle in Magnetic Resonance Imaging

    PubMed Central

    Tufvesson, Jane; Hedström, Erik; Steding-Ehrenborg, Katarina; Carlsson, Marcus; Arheden, Håkan; Heiberg, Einar

    2015-01-01

    Introduction. Manual delineation of the left ventricle is clinical standard for quantification of cardiovascular magnetic resonance images despite being time consuming and observer dependent. Previous automatic methods generally do not account for one major contributor to stroke volume, the long-axis motion. Therefore, the aim of this study was to develop and validate an automatic algorithm for time-resolved segmentation covering the whole left ventricle, including basal slices affected by long-axis motion. Methods. Ninety subjects imaged with a cine balanced steady state free precession sequence were included in the study (training set n = 40, test set n = 50). Manual delineation was reference standard and second observer analysis was performed in a subset (n = 25). The automatic algorithm uses deformable model with expectation-maximization, followed by automatic removal of papillary muscles and detection of the outflow tract. Results. The mean differences between automatic segmentation and manual delineation were EDV −11 mL, ESV 1 mL, EF −3%, and LVM 4 g in the test set. Conclusions. The automatic LV segmentation algorithm reached accuracy comparable to interobserver for manual delineation, thereby bringing automatic segmentation one step closer to clinical routine. The algorithm and all images with manual delineations are available for benchmarking. PMID:26180818

  10. Development and Implementation of a Hardware In-the-Loop Test Bed for Unmanned Aerial Vehicle Control Algorithms

    NASA Technical Reports Server (NTRS)

    Nyangweso, Emmanuel; Bole, Brian

    2014-01-01

    Successful prediction and management of battery life using prognostic algorithms through ground and flight tests is important for performance evaluation of electrical systems. This paper details the design of test beds suitable for replicating loading profiles that would be encountered in deployed electrical systems. The test bed data will be used to develop and validate prognostic algorithms for predicting battery discharge time and battery failure time. Online battery prognostic algorithms will enable health management strategies. The platform used for algorithm demonstration is the EDGE 540T electric unmanned aerial vehicle (UAV). The fully designed test beds developed and detailed in this paper can be used to conduct battery life tests by controlling current and recording voltage and temperature to develop a model that makes a prediction of end-of-charge and end-of-life of the system based on rapid state of health (SOH) assessment.

  11. Time-resolved Emission from Bright Hot Pixels of an Active Region Observed in the EUV Band with SDO/AIA and Multi-stranded Loop Modeling

    NASA Astrophysics Data System (ADS)

    Tajfirouze, E.; Reale, F.; Petralia, A.; Testa, P.

    2016-01-01

    Evidence of small amounts of very hot plasma has been found in active regions and might be an indication of impulsive heating released at spatial scales smaller than the cross-section of a single loop. We investigate the heating and substructure of coronal loops in the core of one such active region by analyzing the light curves in the smallest resolution elements of solar observations in two EUV channels (94 and 335 Å) from the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory. We model the evolution of a bundle of strands heated by a storm of nanoflares by means of a hydrodynamic 0D loop model (EBTEL). The light curves obtained from a random combination of those of single strands are compared to the observed light curves either in a single pixel or in a row of pixels, simultaneously in the two channels, and using two independent methods: an artificial intelligent system (Probabilistic Neural Network) and a simple cross-correlation technique. We explore the space of the parameters to constrain the distribution of the heat pulses, their duration, their spatial size, and, as a feedback on the data, their signatures on the light curves. From both methods the best agreement is obtained for a relatively large population of events (1000) with a short duration (less than 1 minute) and a relatively shallow distribution (power law with index 1.5) in a limited energy range (1.5 decades). The feedback on the data indicates that bumps in the light curves, especially in the 94 Å channel, are signatures of a heating excess that occurred a few minutes before.

  12. Mid-tropospheric Moisture Variations During the Development of Hurricane Karl as Resolved by Airborne GPS Radio Occultation with Open Loop Tracking

    NASA Astrophysics Data System (ADS)

    Haase, J. S.; Murphy, B.; Wang, K. N.; Garrison, J. L.; Adhikari, L.; Xie, F.

    2015-12-01

    The development of hurricane Karl in 2010 was investigated with dropsonde and airborne radio occultation (ARO) measurements from the stage of tropical disturbance within an easterly wave through to genesis of the tropical storm. Infrared imagery showed deep convection with extensive cold cloud tops on 11 September however the storm failed to develop until 3 days later. One possible explanation is the horizontal offset of the mid and lower level circulation centers. We illustrate with airborne radio occultation measurements additional information on the moisture distribution during this stage of development that indicates that average mid-level moisture was lower the following day and then increased again over the next two days prior to development. High sample rate RF data recorded by the GNSS instrument system for multistatic and occultation sensing (GISMOS) was analyzed with a version of the Purdue Software Receiver that has open-loop tracking implemented. Open loop tracking eliminates the feedback loop of conventional receivers that fails in the complex signal propagation environment typical of atmosphere with sharp moisture gradients. The open-loop excess phase profiles routinely sample below 4 km, with half of the profiles extending below 2 km. We retrieve slanted vertical profiles of atmospheric refractivity that can be considered a proxy for moisture in this tropical environment. We illustrate that in the mid to upper troposphere, ARO refractivity profiles sampling different areas within the tropical wave showed characteristics that were consistent with (~150 to 200 km scale) horizontal moisture gradients present in the NWP model representation of the developing tropical storm. Variation in refractivity preceding the development of the pre-Karl system is consistent with increasing moisture near the storm center. The ARO observations almost double the amount of thermodynamic data over that provided by the dropsondes. They provide interesting complementary

  13. Platform for Real-Time Simulation of Dynamic Systems and Hardware-in-the-Loop for Control Algorithms

    PubMed Central

    de Souza, Isaac D. T.; Silva, Sergio N.; Teles, Rafael M.; Fernandes, Marcelo A. C.

    2014-01-01

    The development of new embedded algorithms for automation and control of industrial equipment usually requires the use of real-time testing. However, the equipment required is often expensive, which means that such tests are often not viable. The objective of this work was therefore to develop an embedded platform for the distributed real-time simulation of dynamic systems. This platform, called the Real-Time Simulator for Dynamic Systems (RTSDS), could be applied in both industrial and academic environments. In industrial applications, the RTSDS could be used to optimize embedded control algorithms. In the academic sphere, it could be used to support research into new embedded solutions for automation and control and could also be used as a tool to assist in undergraduate and postgraduate teaching related to the development of projects concerning on-board control systems. PMID:25320906

  14. Platform for real-time simulation of dynamic systems and hardware-in-the-loop for control algorithms.

    PubMed

    de Souza, Isaac D T; Silva, Sergio N; Teles, Rafael M; Fernandes, Marcelo A C

    2014-01-01

    The development of new embedded algorithms for automation and control of industrial equipment usually requires the use of real-time testing. However, the equipment required is often expensive, which means that such tests are often not viable. The objective of this work was therefore to develop an embedded platform for the distributed real-time simulation of dynamic systems. This platform, called the Real-Time Simulator for Dynamic Systems (RTSDS), could be applied in both industrial and academic environments. In industrial applications, the RTSDS could be used to optimize embedded control algorithms. In the academic sphere, it could be used to support research into new embedded solutions for automation and control and could also be used as a tool to assist in undergraduate and postgraduate teaching related to the development of projects concerning on-board control systems. PMID:25320906

  15. The structure of 4-methylphenol and its water cluster revealed by rotationally resolved UV spectroscopy using a genetic algorithm approach

    NASA Astrophysics Data System (ADS)

    Myszkiewicz, Grzegorz; Meerts, W. Leo; Ratzer, Christian; Schmitt, Michael

    2005-07-01

    The structure of 4-methylphenol (p-cresol) and its binary water cluster have been elucidated by rotationally resolved laser-induced fluorescence spectroscopy. The electronic origins of the monomer and the cluster are split into four sub-bands by the internal rotation of the methyl group and of the hydroxy group in case of the monomer, and the water moiety in case of the cluster. From the rotational constants of the monomer the structure in the S1 state could be determined to be distorted quinoidally. The structure of the p-cresol-water cluster is determined to be trans linear, with a O-O hydrogen bond length of 290pm in the electronic ground state and of 285pm in the electronically excited state. The S1-state lifetime of p-cresol, p-cresol-d1, and the binary water cluster have been determined to be 1.6, 9.7, and 3.8ns, respectively.

  16. Resolving of challenging gas chromatography-mass spectrometry peak clusters in fragrance samples using multicomponent factorization approaches based on polygon inflation algorithm.

    PubMed

    Ghaheri, Salehe; Masoum, Saeed; Gholami, Ali

    2016-01-15

    Analysis of fragrance composition is very important for both the fragrance producers and consumers. Unraveling of fragrance formulation is necessary for quality control, competitor and trace analysis. Gas chromatography-mass spectrometry (GC-MS) has been introduced as the most appropriate analytical technique for this type of analysis, which is based on Kovats index and MS database. The most straightforward method to analyze a GC-MS dataset is to integrate those peaks that can be recognized by their mass profiles. But, because of common problems of chromatographic data such as spectral background, baseline offset and specially overlapped peaks, accurate quantitative and qualitative analysis could be failed. Some chemometric modeling techniques such as bilinear multivariate curve resolution (MCR) methods have been introduced to overcome these problems and obtained well resolved chromatographic profiles. The main drawback of these methods is rotational ambiguity or nonunique solution that is represented as area of feasible solutions (AFS). Polygonal inflation algorithm (PIA) is an automatic and simple to use algorithm for numerical computation of AFS. In this study, the extent of rotational ambiguity in curve resolution methods is calculated by MCR-BAND toolbox and the PIA. The ability of the PIA in resolving GC-MS data sets is evaluated by simulated GC-MS data in comparison with other popular curve resolution methods such as multivariate curve resolution alternative least square (MCR-ALS), multivariate curve resolution objective function minimization (MCR-FMIN) by different initial estimation methods and independent component analysis (ICA). In addition, two typical challenging area of total ion chromatogram (TIC) of commercial fragrances with overlapped peaks were analyzed by the PIA to investigate the possibility of peak deconvolution analysis. PMID:26711156

  17. Resolving Off-Nominal Situations in Schedule-Based Terminal Area Operations: Results from a Human-in-the-Loop Simulation

    NASA Technical Reports Server (NTRS)

    Mercer, Joey; Callantine, Todd; Martin, Lynne

    2012-01-01

    A recent human-in-the-loop simulation in the Airspace Operations Laboratory (AOL) at NASA's Ames Research Center investigated the robustness of Controller-Managed Spacing (CMS) operations. CMS refers to AOL-developed controller tools and procedures for enabling arrivals to conduct efficient Optimized Profile Descents with sustained high throughput. The simulation provided a rich data set for examining how a traffic management supervisor and terminal-area controller participants used the CMS tools and coordinated to respond to off-nominal events. This paper proposes quantitative measures for characterizing the participants responses. Case studies of go-around events, replicated during the simulation, provide insights into the strategies employed and the role the CMS tools played in supporting them.

  18. Development of an algorithm to regulate pump output for a closed air-loop type pneumatic biventricular assist device.

    PubMed

    Nam, Kyoung Won; Lee, Jung Joo; Hwang, Chang Mo; Choi, Jaesoon; Choi, Hyuk; Choi, Seong Wook; Sun, Kyung

    2009-12-01

    The closed air space-type of extracorporeal pneumatic ventricular assist device (VAD) developed by the Korea Artificial Organ Center utilizes a bellows-transforming mechanism to generate the air pressure required to pump blood. This operating mechanism can reduce the size and weight of the driving unit; however, the output of the blood pump can be affected by the pressure loading conditions of the blood sac. Therefore, to guarantee a proper pump output level, regardless of the pressure loading conditions that vary over time, automatic pump output regulation of the blood pump is required. We describe herein a pump output regulation algorithm that was developed to maintain pump output around a reference level against various afterload pressures, and verified the pump performance in vitro. Based on actual operating conditions in animal experiments, the pumping rate was limited to 40-84 beats per minute, and the afterload pressure was limited to 80-150 mm Hg. The tested reference pump output was 4.0 L/min. During experiments, the pump output was successfully and automatically regulated within the preset area regardless of the varying afterload conditions. The results of this preliminary experiment can be used as the basis for an automatic control algorithm that can enhance the stability and reliability of the applied VAD. PMID:19604228

  19. Mapping hydrogeophysical structures with time--domain electromagnetic methods: Resolving small-scale details with large loops and three--component measurements

    NASA Astrophysics Data System (ADS)

    Weiss, C. J.; Li, Y.; Nabighian, M.

    2004-12-01

    One of the outstanding problems in managing water resources in geologically complex aquifers is to develop improved techniques for mapping compartmentalization due to faulting. And although the role of faults in aquifer dynamics can vary considerably, knowledge of their location is key to understanding aquifer recharge and developing a sensible model for predicting aquifer response due to anthropogenic loads. We have explored the application of time--domain electromagnetic methods for mapping shallow aquifer faults on the western flanks of the Estancia Basin, central New Mexico. The field site is underlain by massive Pennsylvanian limestones (Madera Group) subsequently faulted by Laramide tectonics of the Ancestral Rockies and Neogene extension of the Rio Grande Rift. Two experimental configurations were deployed: a large 50 × 40 m transmitter loop with receiver stations located on a 5 m grid over the loop's interior; and an azimuthal survey consisting of a smaller fixed transmitter with receiver stations at ˜2 m intervals along a 30 m radius circle centered on the transmitter. Three--component transients of magnetic field due to a fast linear ramp--off in the transmitter were recorded at each station. As a rapid reconnaisance tool, the azimuthal experiment is well--suited for identification of subsurface fault planes since symmetry constraints require a vanishing azimuthal ̂ φ component of magnetic field when the electrical strike, or fault plane, lies in the ̂ φ direction. However, each of the experimental configurations revealed that the site's electrical structure is far more three--dimensional than previously believed and is not dominated by the response of a previously identified fault plane. Instead, we have observed spatially coherent transient signals which may indicate compartmentalization over length scales as small as a few tens of meters. Sections of this work were performed at Sandia National Laboratories. Sandia is a multi--program laboratory

  20. Regulative Loops, Step Loops and Task Loops

    ERIC Educational Resources Information Center

    VanLehn, Kurt

    2016-01-01

    This commentary suggests a generalization of the conception of the behavior of tutoring systems, which the target article characterized as having an outer loop that was executed once per task and an inner loop that was executed once per step of the task. A more general conception sees these two loops as instances of regulative loops, which…

  1. Automatic one-loop calculations with Sherpa+OpenLoops

    NASA Astrophysics Data System (ADS)

    Cascioli, F.; Höche, S.; Krauss, F.; Maierhöfer, P.; Pozzorini, S.; Siegert, F.

    2014-06-01

    We report on the OpenLoops generator for one-loop matrix elements and its application to four-lepton production in association with up to one jet. The open loops algorithm uses a numerical recursion to construct the numerator of one-loop Feynman diagrams as functions of the loop momentum. In combination with tensor integrals this results in a highly efficient and numerically stable matrix element generator. In order to obtain a fully automated setup for the simulation of next-to-leading order scattering processes we interfaced OpenLoops to the Sherpa Monte Carlo event generator.

  2. Automatic blocking of nested loops

    NASA Technical Reports Server (NTRS)

    Schreiber, Robert; Dongarra, Jack J.

    1990-01-01

    Blocked algorithms have much better properties of data locality and therefore can be much more efficient than ordinary algorithms when a memory hierarchy is involved. On the other hand, they are very difficult to write and to tune for particular machines. The reorganization is considered of nested loops through the use of known program transformations in order to create blocked algorithms automatically. The program transformations used are strip mining, loop interchange, and a variant of loop skewing in which invertible linear transformations (with integer coordinates) of the loop indices are allowed. Some problems are solved concerning the optimal application of these transformations. It is shown, in a very general setting, how to choose a nearly optimal set of transformed indices. It is then shown, in one particular but rather frequently occurring situation, how to choose an optimal set of block sizes.

  3. Higher dimensional loop quantum cosmology

    NASA Astrophysics Data System (ADS)

    Zhang, Xiangdong

    2016-07-01

    Loop quantum cosmology (LQC) is the symmetric sector of loop quantum gravity. In this paper, we generalize the structure of loop quantum cosmology to the theories with arbitrary spacetime dimensions. The isotropic and homogeneous cosmological model in n+1 dimensions is quantized by the loop quantization method. Interestingly, we find that the underlying quantum theories are divided into two qualitatively different sectors according to spacetime dimensions. The effective Hamiltonian and modified dynamical equations of n+1 dimensional LQC are obtained. Moreover, our results indicate that the classical big bang singularity is resolved in arbitrary spacetime dimensions by a quantum bounce. We also briefly discuss the similarities and differences between the n+1 dimensional model and the 3+1 dimensional one. Our model serves as a first example of higher dimensional loop quantum cosmology and offers the possibility to investigate quantum gravity effects in higher dimensional cosmology.

  4. Fast loop modeling for protein structures

    NASA Astrophysics Data System (ADS)

    Zhang, Jiong; Nguyen, Son; Shang, Yi; Xu, Dong; Kosztin, Ioan

    2015-03-01

    X-ray crystallography is the main method for determining 3D protein structures. In many cases, however, flexible loop regions of proteins cannot be resolved by this approach. This leads to incomplete structures in the protein data bank, preventing further computational study and analysis of these proteins. For instance, all-atom molecular dynamics (MD) simulation studies of structure-function relationship require complete protein structures. To address this shortcoming, we have developed and implemented an efficient computational method for building missing protein loops. The method is database driven and uses deep learning and multi-dimensional scaling algorithms. We have implemented the method as a simple stand-alone program, which can also be used as a plugin in existing molecular modeling software, e.g., VMD. The quality and stability of the generated structures are assessed and tested via energy scoring functions and by equilibrium MD simulations. The proposed method can also be used in template-based protein structure prediction. Work supported by the National Institutes of Health [R01 GM100701]. Computer time was provided by the University of Missouri Bioinformatics Consortium.

  5. Control algorithm for the inverter fed induction motor drive with DC current feedback loop based on principles of the vector control

    SciTech Connect

    Vuckovic, V.; Vukosavic, S. )

    1992-01-01

    This paper brings out a control algorithm for VSI fed induction motor drives based on the converter DC link current feedback. It is shown that the speed and flux can be controlled over the wide speed and load range quite satisfactorily for simpler drives. The base commands of both the inverter voltage and frequency are proportional to the reference speed, but each of them is further modified by the signals derived from the DC current sensor. The algorithm is based on the equations well known from the vector control theory, and is aimed to obtain the constant rotor flux and proportionality between the electrical torque, the slip frequency and the active component of the stator current. In this way, the problems of slip compensation, Ri compensation and correction of U/f characteristics are solved in the same time. Analytical considerations and computer simulations of the proposed control structure are in close agreement with the experimental results measured on a prototype drive.

  6. Time-resolved cardiac interventional cone-beam CT reconstruction from fully truncated projections using the prior image constrained compressed sensing (PICCS) algorithm

    NASA Astrophysics Data System (ADS)

    Thériault Lauzier, Pascal; Tang, Jie; Chen, Guang-Hong

    2012-05-01

    C-arm cone-beam CT could replace preoperative multi-detector CT scans in the cardiac interventional setting. However, cardiac gating results in view angle undersampling and the small size of the detector results in projection data truncation. These problems are incompatible with conventional tomographic reconstruction algorithms. In this paper, the prior image constrained compressed sensing (PICCS) reconstruction method was adapted to solve these issues. The performance of the proposed method was compared to that of FDK, FDK with extrapolated projection data (E-FDK), and total variation-based compressed sensing. A canine projection dataset acquired using a clinical C-arm imaging system supplied realistic cardiac motion and anatomy for this evaluation. Three different levels of truncation were simulated. The relative root mean squared error and the universal image quality index were used to quantify the reconstruction accuracy. Three main conclusions were reached. (1) The adapted version of the PICCS algorithm offered the highest image quality and reconstruction accuracy. (2) No meaningful variation in performance was observed when the amount of truncation was changed. (3) This study showed evidence that accurate interior tomography with an undersampled acquisition is possible for realistic objects if a prior image with minimal artifacts is available.

  7. Loop-to-loop coupling.

    SciTech Connect

    Warne, Larry Kevin; Lucero, Larry Martin; Langston, William L.; Salazar, Robert Austin; Coleman, Phillip Dale; Basilio, Lorena I.; Bacon, Larry Donald

    2012-05-01

    This report estimates inductively-coupled energy to a low-impedance load in a loop-to-loop arrangement. Both analytical models and full-wave numerical simulations are used and the resulting fields, coupled powers and energies are compared. The energies are simply estimated from the coupled powers through approximations to the energy theorem. The transmitter loop is taken to be either a circular geometry or a rectangular-loop (stripline-type) geometry that was used in an experimental setup. Simple magnetic field models are constructed and used to estimate the mutual inductance to the receiving loop, which is taken to be circular with one or several turns. Circuit elements are estimated and used to determine the coupled current and power (an equivalent antenna picture is also given). These results are compared to an electromagnetic simulation of the transmitter geometry. Simple approximate relations are also given to estimate coupled energy from the power. The effect of additional loads in the form of attached leads, forming transmission lines, are considered. The results are summarized in a set of susceptibility-type curves. Finally, we also consider drives to the cables themselves and the resulting common-to-differential mode currents in the load.

  8. RCD+: Fast loop modeling server

    PubMed Central

    López-Blanco, José Ramón; Canosa-Valls, Alejandro Jesús; Li, Yaohang; Chacón, Pablo

    2016-01-01

    Modeling loops is a critical and challenging step in protein modeling and prediction. We have developed a quick online service (http://rcd.chaconlab.org) for ab initio loop modeling combining a coarse-grained conformational search with a full-atom refinement. Our original Random Coordinate Descent (RCD) loop closure algorithm has been greatly improved to enrich the sampling distribution towards near-native conformations. These improvements include a new workflow optimization, MPI-parallelization and fast backbone angle sampling based on neighbor-dependent Ramachandran probability distributions. The server starts by efficiently searching the vast conformational space from only the loop sequence information and the environment atomic coordinates. The generated closed loop models are subsequently ranked using a fast distance-orientation dependent energy filter. Top ranked loops are refined with the Rosetta energy function to obtain accurate all-atom predictions that can be interactively inspected in an user-friendly web interface. Using standard benchmarks, the average root mean squared deviation (RMSD) is 0.8 and 1.4 Å for 8 and 12 residues loops, respectively, in the challenging modeling scenario in where the side chains of the loop environment are fully remodeled. These results are not only very competitive compared to those obtained with public state of the art methods, but also they are obtained ∼10-fold faster. PMID:27151199

  9. RCD+: Fast loop modeling server.

    PubMed

    López-Blanco, José Ramón; Canosa-Valls, Alejandro Jesús; Li, Yaohang; Chacón, Pablo

    2016-07-01

    Modeling loops is a critical and challenging step in protein modeling and prediction. We have developed a quick online service (http://rcd.chaconlab.org) for ab initio loop modeling combining a coarse-grained conformational search with a full-atom refinement. Our original Random Coordinate Descent (RCD) loop closure algorithm has been greatly improved to enrich the sampling distribution towards near-native conformations. These improvements include a new workflow optimization, MPI-parallelization and fast backbone angle sampling based on neighbor-dependent Ramachandran probability distributions. The server starts by efficiently searching the vast conformational space from only the loop sequence information and the environment atomic coordinates. The generated closed loop models are subsequently ranked using a fast distance-orientation dependent energy filter. Top ranked loops are refined with the Rosetta energy function to obtain accurate all-atom predictions that can be interactively inspected in an user-friendly web interface. Using standard benchmarks, the average root mean squared deviation (RMSD) is 0.8 and 1.4 Å for 8 and 12 residues loops, respectively, in the challenging modeling scenario in where the side chains of the loop environment are fully remodeled. These results are not only very competitive compared to those obtained with public state of the art methods, but also they are obtained ∼10-fold faster. PMID:27151199

  10. Closing the loop.

    PubMed

    Dassau, E; Atlas, E; Phillip, M

    2011-02-01

    Closed-loop algorithms can be found in every aspect of everyday modern life. Automation and control are used constantly to provide safety and to improve quality of life. Closed-loop systems and algorithms can be found in home appliances, automobiles, aviation and more. Can one imagine nowadays driving a car without ABS, cruise control or even anti-sliding control? Similar principles of automation and control can be used in the management of diabetes mellitus (DM). The idea of an algorithmic/technological way to control glycaemia is not new and has been researched for more than four decades. However, recent improvements in both glucose-sensing technology and insulin delivery together with advanced control and systems engineering made this dream of an artificial pancreas possible. The artificial pancreas may be the next big step in the treatment of DM since the use of insulin analogues. An artificial pancreas can be described as internal or external devices that use continuous glucose measurements to automatically manage exogenous insulin delivery with or without other hormones in an attempt to restore glucose regulation in individuals with DM using a control algorithm. This device as described can be internal or external; can use different types of control algorithms with bi-hormonal or uni-hormonal design; and can utilise different ways to administer them. The different designs and implementations have transitioned recently from in silico simulations to clinical evaluation stage with practical applications in mind. This may mark the beginning of a new era in diabetes management with the introduction of semi-closed-loop systems that can prevent or minimise nocturnal hypoglycaemia, to hybrid systems that will manage blood glucose (BG) levels with minimal user intervention to finally fully automated systems that will take the user out of the loop. More and more clinical trials will be needed for the artificial pancreas to become a reality but initial encouraging

  11. Testing block subdivision algorithms on block designs

    NASA Astrophysics Data System (ADS)

    Wiseman, Natalie; Patterson, Zachary

    2016-01-01

    Integrated land use-transportation models predict future transportation demand taking into account how households and firms arrange themselves partly as a function of the transportation system. Recent integrated models require parcels as inputs and produce household and employment predictions at the parcel scale. Block subdivision algorithms automatically generate parcel patterns within blocks. Evaluating block subdivision algorithms is done by way of generating parcels and comparing them to those in a parcel database. Three block subdivision algorithms are evaluated on how closely they reproduce parcels of different block types found in a parcel database from Montreal, Canada. While the authors who developed each of the algorithms have evaluated them, they have used their own metrics and block types to evaluate their own algorithms. This makes it difficult to compare their strengths and weaknesses. The contribution of this paper is in resolving this difficulty with the aim of finding a better algorithm suited to subdividing each block type. The proposed hypothesis is that given the different approaches that block subdivision algorithms take, it's likely that different algorithms are better adapted to subdividing different block types. To test this, a standardized block type classification is used that consists of mutually exclusive and comprehensive categories. A statistical method is used for finding a better algorithm and the probability it will perform well for a given block type. Results suggest the oriented bounding box algorithm performs better for warped non-uniform sites, as well as gridiron and fragmented uniform sites. It also produces more similar parcel areas and widths. The Generalized Parcel Divider 1 algorithm performs better for gridiron non-uniform sites. The Straight Skeleton algorithm performs better for loop and lollipop networks as well as fragmented non-uniform and warped uniform sites. It also produces more similar parcel shapes and patterns.

  12. Closed-loop anesthesia.

    PubMed

    LE Guen, Morgan; Liu, Ngai; Chazot, Thierry; Fischler, Marc

    2016-05-01

    Automated anesthesia which may offer to the physician time to control hemodynamic and to supervise neurological outcome and which may offer to the patient safety and quality was until recently consider as a holy grail. But this field of research is now increasing in every component of general anesthesia (hypnosis, nociception, neuromuscular blockade) and literature describes some successful algorithms - single or multi closed-loop controller. The aim of these devices is to control a predefined target and to continuously titrate anesthetics whatever the patients' co morbidities and surgical events to reach this target. Literature contains many randomized trials comparing manual and automated anesthesia and shows feasibility and safety of this system. Automation could quickly concern other aspects of anesthesia as fluid management and this review proposes an overview of closed-loop systems in anesthesia. PMID:26554614

  13. Application of a Genetic Algorithm in a Collaborative Process to Resolve Hydrology and Physical Reality with Both Western and Maori Cultural Values

    NASA Astrophysics Data System (ADS)

    Sheer, D.; Sheer, A.; Lebherz, S.

    2009-12-01

    Lakes Rotorua and Rotoiti are two sizeable, culturally and economically important lakes on the North Island of New Zealand. Rotorua outflows traverse the short Ohau Channel before entering Lake Rotoiti. Ohau channel flows are partially controlled by a stoplog structure. Rotoiti outflows to the Kaituna River are fully controlled by the Okere Gate structure. The structures are managed by Environment Bay of Plenty (EBOP), a government agency. Management objectives include maintaining minimum lake levels to support recreational boating, restricting maximum lake levels to avoid residential flooding, minimum instream flows below the lower lake to maintain aquatic ecosystems, limits on maximum releases to control erosion and prevent flooding. In addition, management seeks to provide for a minimum annual variation in lake levels to control the growth of aquatic plants in the littoral zone and to periodically expose beaches with important cultural value to the indigenous Maori population. The levels necessary to expose beaches may be lower than the minimum levels desired to support boating. Records of beach exposure are scant; the existence of beaches may depend on climate cycles. There is flow dependent recreational rafting below Okere Gates. This rafting is economically valuable, but is also contentious because the reach of Kaituna River flows through important Maori cultural areas, including grave sites. The Maoris have expressed a preference for replacing the Okere Gates with a fixed stepped weir, although the existing gates can be relatively easily operated to reproduce the flows over any of the fixed weir designs so far proposed. HydroLogics created a model of the two-lake system using its OASIS software system. The inflows to the lakes were estimated based on available historical flow and lake level data and on flow estimates derived from Mike-11 modeling of historical lake outlet configurations. A custom genetic algorithm (GA) was created to “wrap” the

  14. Manchester transition tracking loop (MTTL)

    NASA Technical Reports Server (NTRS)

    Cellier, A.; Ma, L. N.; Huey, D. C.

    1977-01-01

    In new tracking loop, separate phase detection algorithm is incorporated for acquisition; programmed acquisition-to-track sequence includes automatic bandwidth switching. Additionally, system has very effective phase detection signal-to-noise ratio and can operate at any rate by changing master clock frequency. All system parameters remain constant.

  15. Design and Evaluation in a Real Use-case of Closed-loop Scheduling Algorithms for the gLite Workload Management System

    NASA Astrophysics Data System (ADS)

    Andreetto, P.; Bauce, M.; Bertocco, S.; Capannini, F.; Cecchi, M.; Compostella, G.; Dorigo, A.; Frizziero, E.; Giacomini, F.; Gianelle, A.; Lucchesi, D.; Mezzadri, M.; Monforte, S.; Prelz, F.; Molinari, E.; Rebatto, D.; Sgaravatto, M.; Zangrando, L.

    2011-12-01

    The High Throughput Computing paradigm typically involves a scenario whereby a given, estimated processing power is made available and sustained by the computing environment over a medium/long period of time. As a consequence, the performance goals are in general targeted at maximizing resource utilization to obtain the expected throughput, rather than minimizing run time for individual jobs. This does not mean that optimal resource selection through adequate workload management is not desired nor effective, nonetheless, relatively small and pre-assessed percentages of suboptimal choices or unexpected events can be tolerated. However, there are use-cases, among the HEP community, for which the described model does not immediately fit. This paper deals with the workload needs primarily driven by the Collider Detector at Fermilab (CDF) experimental collaboration. In particular, the CDF analysis facility (CAF) typically operates by splitting its computations into so-called sections, which can be seen as sets of uniform and independent jobs. Processing a section cannot be considered completed until all _its jobs have been successfully executed, thus requiring a Minimum Completion Time (MCT) dynamic scheduling policy where not even a single job should lay in non-terminal Grid states. A significant part of the CDF analysis is processed on the European Grid infrastructure through the gLite Workload Management System (WMS) [2]. This paper describes the design enhancements and ranking algorithms the WMS has been provided with to implement an adaptive scheduling policy to minimise MCT. Case study, outlined approach and first results are presented.

  16. Thermal Analysis of CDS Coronal Loops

    NASA Astrophysics Data System (ADS)

    Kimble, J. A.; Schmelz, J. T.; Nasraoui, K.; Rightmire, L. A.; Andrews, J. M.; Cirtain, J. W.

    2008-05-01

    The coronal loop data used for this analysis was obtained using the Coronal Diagnostic Spectrometer (CDS) aboard the Solar and Heliospheric Observatory on 2003 January 17 at 14:24:43 UT. We use the Chianti atomic physics database and the hybrid coronal abundances to determine temperatures and densities for positions along several loops. We chose six pixels along each loop as well as background pixels. The intensities of the background pixels are subtracted from each loop pixel to isolate the emission from the loop pixel, and then spectral lines with significant contributions to the loop intensities are selected. The loops were then analyzed with a forward folding process to produce differential emission measure (DEM) curves. Emission measure loci plots and DEM automatic inversions are then used to verify those conclusions. We find different results for each of these loops. One appears to be isothermal at each loop position, and the temperature does not change with height. The second appears to be multithermal at each position and the third seems to be consistent with two DEM spikes, which might indicate that there are two isothermal loops so close together, that they are not resolved by CDS. Solar physics research at the University of Memphis is supported by a Hinode subcontract from NASA/SAO as well as NSF ATM-0402729.

  17. Efficient Tiled Loop Generation: D-Tiling

    NASA Astrophysics Data System (ADS)

    Kim, Daegon; Rajopadhye, Sanjay

    Tiling is an important loop optimization for exposing coarse-grained parallelism and enhancing data locality. Tiled loop generation from an arbitrarily shaped polyhedron is a well studied problem. Except for the special case of a rectangular iteration space, the tiled loop generation problem has been long believed to require heavy machinery such as Fourier-Motzkin elimination and projection, and hence to have an exponential complexity. In this paper we propose a simple and efficient tiled loop generation technique similar to that for a rectangular iteration space. In our technique, each loop bound is adjusted only once, syntactically and independently. Therefore, our algorithm runs linearly with the number of loop bounds. Despite its simplicity, we retain several advantages of recent tiled code generation schemes - unified generation for fixed, parameterized and hybrid tiled loops, scalability for multi-level tiled loop generation with the ability to separate full tiles at any levels, and compact code. We also explore various schemes for multi-level tiled loop generation. We formally prove the correctness of our scheme and experimentally validate that the efficiency of our technique is comparable to existing parameterized tiled loop generation approaches. Our experimental results also show that multi-level tiled loop generation schemes have an impact on performance of generated code. The fact that our scheme can be implemented without sophisticated machinery makes it well suited for autotuners and production compilers.

  18. Ekpyrotic loop quantum cosmology

    SciTech Connect

    Wilson-Ewing, Edward

    2013-08-01

    We consider the ekpyrotic paradigm in the context of loop quantum cosmology. In loop quantum cosmology the classical big-bang singularity is resolved due to quantum gravity effects, and so the contracting ekpyrotic branch of the universe and its later expanding phase are connected by a smooth bounce. Thus, it is possible to explicitly determine the evolution of scalar perturbations, from the contracting ekpyrotic phase through the bounce and to the post-bounce expanding epoch. The possibilities of having either one or two scalar fields have been suggested for the ekpyrotic universe, and both cases will be considered here. In the case of a single scalar field, the constant mode of the curvature perturbations after the bounce is found to have a blue spectrum. On the other hand, for the two scalar field ekpyrotic model where scale-invariant entropy perturbations source additional terms in the curvature perturbations, the power spectrum in the post-bounce expanding cosmology is shown to be nearly scale-invariant and so agrees with observations.

  19. RESOLVE Project

    NASA Technical Reports Server (NTRS)

    Parker, Ray; Coan, Mary; Cryderman, Kate; Captain, Janine

    2013-01-01

    The RESOLVE project is a lunar prospecting mission whose primary goal is to characterize water and other volatiles in lunar regolith. The Lunar Advanced Volatiles Analysis (LAVA) subsystem is comprised of a fluid subsystem that transports flow to the gas chromatograph - mass spectrometer (GC-MS) instruments that characterize volatiles and the Water Droplet Demonstration (WDD) that will capture and display water condensation in the gas stream. The LAVA Engineering Test Unit (ETU) is undergoing risk reduction testing this summer and fall within a vacuum chamber to understand and characterize component and integrated system performance. Testing of line heaters, printed circuit heaters, pressure transducers, temperature sensors, regulators, and valves in atmospheric and vacuum environments was done. Test procedures were developed to guide experimental tests and test reports to analyze and draw conclusions from the data. In addition, knowledge and experience was gained with preparing a vacuum chamber with fluid and electrical connections. Further testing will include integrated testing of the fluid subsystem with the gas supply system, near-infrared spectrometer, WDD, Sample Delivery System, and GC-MS in the vacuum chamber. This testing will provide hands-on exposure to a flight forward spaceflight subsystem, the processes associated with testing equipment in a vacuum chamber, and experience working in a laboratory setting. Examples of specific analysis conducted include: pneumatic analysis to calculate the WDD's efficiency at extracting water vapor from the gas stream to form condensation; thermal analysis of the conduction and radiation along a line connecting two thermal masses; and proportional-integral-derivative (PID) heater control analysis. Since LAVA is a scientific subsystem, the near-infrared spectrometer and GC-MS instruments will be tested during the ETU testing phase.

  20. Rollercoaster Loop Shapes

    ERIC Educational Resources Information Center

    Pendrill, Ann-Marie

    2005-01-01

    Many modern rollercoasters feature loops. Although textbook loops are often circular, real rollercoaster loops are not. In this paper, we look into the mathematical description of various possible loop shapes, as well as their riding properties. We also discuss how a study of loop shapes can be used in physics education.

  1. Rollercoaster loop shapes

    NASA Astrophysics Data System (ADS)

    Pendrill, Ann-Marie

    2005-11-01

    Many modern rollercoasters feature loops. Although textbook loops are often circular, real rollercoaster loops are not. In this paper, we look into the mathematical description of various possible loop shapes, as well as their riding properties. We also discuss how a study of loop shapes can be used in physics education.

  2. RESOLVE Project

    NASA Technical Reports Server (NTRS)

    Parker, Ray O.

    2012-01-01

    The RESOLVE project is a lunar prospecting mission whose primary goal is to characterize water and other volatiles in lunar regolith. The Lunar Advanced Volatiles Analysis (LAVA) subsystem is comprised of a fluid subsystem that transports flow to the gas chromatograph- mass spectrometer (GC-MS) instruments that characterize volatiles and the Water Droplet Demonstration (WDD) that will capture and display water condensation in the gas stream. The LAVA Engineering Test Unit (ETU) is undergoing risk reduction testing this summer and fall within a vacuum chamber to understand and characterize C!Jmponent and integrated system performance. Ray will be assisting with component testing of line heaters, printed circuit heaters, pressure transducers, temperature sensors, regulators, and valves in atmospheric and vacuum environments. He will be developing procedures to guide these tests and test reports to analyze and draw conclusions from the data. In addition, he will gain experience with preparing a vacuum chamber with fluid and electrical connections. Further testing will include integrated testing of the fluid subsystem with the gas supply system, near-infrared spectrometer, WDD, Sample Delivery System, and GC-MS in the vacuum chamber. This testing will provide hands-on exposure to a flight forward spaceflight subsystem, the processes associated with testing equipment in a vacuum chamber, and experience working in a laboratory setting. Examples of specific analysis Ray will conduct include: pneumatic analysis to calculate the WOO's efficiency at extracting water vapor from the gas stream to form condensation; thermal analysis of the conduction and radiation along a line connecting two thermal masses; and proportional-integral-derivative (PID) heater control analysis. In this Research and Technology environment, Ray will be asked to problem solve real-time as issues arise. Since LAVA is a scientific subsystem, Ray will be utilizing his chemical engineering background to

  3. Water Stream "Loop-the-Loop"

    ERIC Educational Resources Information Center

    Jefimenko, Oleg

    1974-01-01

    Discusses the design of a modified loop-the-loop apparatus in which a water stream is used to illustrate centripetal forces and phenomena of high-velocity hydrodynamics. Included are some procedures of carrying out lecture demonstrations. (CC)

  4. Coronal Loops: Observations and Modeling of Confined Plasma

    NASA Astrophysics Data System (ADS)

    Reale, Fabio

    2014-07-01

    Coronal loops are the building blocks of the X-ray bright solar corona. They owe their brightness to the dense confined plasma, and this review focuses on loops mostly as structures confining plasma. After a brief historical overview, the review is divided into two separate but not independent parts: the first illustrates the observational framework, the second reviews the theoretical knowledge. Quiescent loops and their confined plasma are considered and, therefore, topics such as loop oscillations and flaring loops (except for non-solar ones, which provide information on stellar loops) are not specifically addressed here. The observational section discusses the classification, populations, and the morphology of coronal loops, its relationship with the magnetic field, and the loop stranded structure. The section continues with the thermal properties and diagnostics of the loop plasma, according to the classification into hot, warm, and cool loops. Then, temporal analyses of loops and the observations of plasma dynamics, hot and cool flows, and waves are illustrated. In the modeling section, some basics of loop physics are provided, supplying fundamental scaling laws and timescales, a useful tool for consultation. The concept of loop modeling is introduced and models are divided into those treating loops as monolithic and static, and those resolving loops into thin and dynamic strands. More specific discussions address modeling the loop fine structure and the plasma flowing along the loops. Special attention is devoted to the question of loop heating, with separate discussion of wave (AC) and impulsive (DC) heating. Large-scale models including atmosphere boxes and the magnetic field are also discussed. Finally, a brief discussion about stellar coronal loops is followed by highlights and open questions.

  5. Algorithms and Algorithmic Languages.

    ERIC Educational Resources Information Center

    Veselov, V. M.; Koprov, V. M.

    This paper is intended as an introduction to a number of problems connected with the description of algorithms and algorithmic languages, particularly the syntaxes and semantics of algorithmic languages. The terms "letter, word, alphabet" are defined and described. The concept of the algorithm is defined and the relation between the algorithm and…

  6. OPE for super loops

    NASA Astrophysics Data System (ADS)

    Sever, Amit; Vieira, Pedro; Wang, Tianheng

    2011-11-01

    We extend the Operator Product Expansion for Null Polygon Wilson loops to the Mason-Skinner-Caron-Huot super loop dual to non MHV gluon amplitudes. We explain how the known tree level amplitudes can be promoted into an infinite amount of data at any loop order in the OPE picture. As an application, we re-derive all one loop NMHV six gluon amplitudes by promoting their tree level expressions. We also present some new all loops predictions for these amplitudes.

  7. The preprocessed doacross loop

    NASA Technical Reports Server (NTRS)

    Saltz, Joel H.; Mirchandaney, Ravi

    1990-01-01

    Dependencies between loop iterations cannot always be characterized during program compilation. Doacross loops typically make use of a-priori knowledge of inter-iteration dependencies to carry out required synchronizations. A type of doacross loop is proposed that allows the scheduling of iterations of a loop among processors without advance knowledge of inter-iteration dependencies. The method proposed for loop iterations requires that parallelizable preprocessing and postprocessing steps be carried out during program execution.

  8. Fast flux locked loop

    DOEpatents

    Ganther, Jr., Kenneth R.; Snapp, Lowell D.

    2002-09-10

    A flux locked loop for providing an electrical feedback signal, the flux locked loop employing radio-frequency components and technology to extend the flux modulation frequency and tracking loop bandwidth. The flux locked loop of the present invention has particularly useful application in read-out electronics for DC SQUID magnetic measurement systems, in which case the electrical signal output by the flux locked loop represents an unknown magnetic flux applied to the DC SQUID.

  9. Hot topic, warm loops, cooling plasma? Multithermal analysis of active region loops

    SciTech Connect

    Schmelz, J. T.; Pathak, S.; Christian, G. M.; Dhaliwal, R. S.; Brooks, D. H.

    2014-11-10

    We have found indications of a relationship between the differential emission measure (DEM) weighted temperature and the cross-field DEM width for coronal loops. The data come from the Hinode X-ray Telescope, the Hinode EUV Imaging Spectrometer, and the Solar Dynamics Observatory Atmospheric Imaging Assembly. These data show that cooler loops tend to have narrower DEM widths. If most loops observed by these instruments are composed of bundles of unresolved magnetic strands and are only observed in their cooling phase, as some studies have suggested, then this relationship implies that the DEM of a coronal loop narrows as it cools. This could imply that fewer strands are seen emitting in the later cooling phase, potentially resolving the long standing controversy of whether the cross-field temperatures of coronal loops are multithermal or isothermal.

  10. Parametric Multi-Level Tiling of Imperfectly Nested Loops

    SciTech Connect

    Hartono, Albert; Baskaran, Muthu M.; Bastoul, Cedric; Cohen, Albert; Krishnamoorthy, Sriram; Norris, Boyana; Ramanujam, J.; Sadayappan, Ponnuswamy

    2009-05-18

    Tiling is a critical loop transformation for generating high-performance code on modern architectures. Efficient generation of multilevel tiled code is essential to exploit several levels of parallelism and/or to maximize data reuse in deep memory hierarchies. Tiled loops with parameterized tile sizes (not compile time constants) facilitate runtime feedback and dynamic optimizations used in iterative compilation and automatic tuning. The existing parametric multilevel tiling approach has focused on transformation for perfectly nested loops, where all assignment statements are contained inside the innermost loop of a loop nest. Previous solutions to tiling for imperfect loop nests are limited to the case where tile sizes are fixed. In this paper, we present an approach to parameterized multilevel tiling for imperfectly nested loops. Our tiling algorithm generates loops that iterate over full rectangular tiles that are amenable for potential compiler optimizations such as register tiling. Experimental results using a number of computational benchmarks demonstrate the effectiveness of our tiling approach.

  11. The Statistical Loop Analyzer (SLA)

    NASA Technical Reports Server (NTRS)

    Lindsey, W. C.

    1985-01-01

    The statistical loop analyzer (SLA) is designed to automatically measure the acquisition, tracking and frequency stability performance characteristics of symbol synchronizers, code synchronizers, carrier tracking loops, and coherent transponders. Automated phase lock and system level tests can also be made using the SLA. Standard baseband, carrier and spread spectrum modulation techniques can be accomodated. Through the SLA's phase error jitter and cycle slip measurements the acquisition and tracking thresholds of the unit under test are determined; any false phase and frequency lock events are statistically analyzed and reported in the SLA output in probabilistic terms. Automated signal drop out tests can be performed in order to trouble shoot algorithms and evaluate the reacquisition statistics of the unit under test. Cycle slip rates and cycle slip probabilities can be measured using the SLA. These measurements, combined with bit error probability measurements, are all that are needed to fully characterize the acquisition and tracking performance of a digital communication system.

  12. Blind loop syndrome

    MedlinePlus

    Blind loop syndrome occurs when digested food slows or stops moving through part of the intestines. This ... The name of this condition refers to the "blind loop" formed by part of the intestine that ...

  13. An efficient algorithm for planar drawing of RNA structures with pseudoknots of any type.

    PubMed

    Byun, Yanga; Han, Kyungsook

    2016-06-01

    An RNA pseudoknot is a tertiary structural element in which bases of a loop pair with complementary bases are outside the loop. A drawing of RNA secondary structures is a tree, but a drawing of RNA pseudoknots is a graph that has an inner cycle within a pseudoknot and possibly outer cycles formed between the pseudoknot and other structural elements. Visualizing a large-scale RNA structure with pseudoknots as a planar drawing is challenging because a planar drawing of an RNA structure requires both pseudoknots and an entire structure enclosing the pseudoknots to be embedded into a plane without overlapping or crossing. This paper presents an efficient heuristic algorithm for visualizing a pseudoknotted RNA structure as a planar drawing. The algorithm consists of several parts for finding crossing stems and page mapping the stems, for the layout of stem-loops and pseudoknots, and for overlap detection between structural elements and resolving it. Unlike previous algorithms, our algorithm generates a planar drawing for a large RNA structure with pseudoknots of any type and provides a bracket view of the structure. It generates a compact and aesthetic structure graph for a large pseudoknotted RNA structure in O([Formula: see text]) time, where n is the number of stems of the RNA structure. PMID:26932273

  14. The adaptive-loop-gain adaptive-scale CLEAN deconvolution of radio interferometric images

    NASA Astrophysics Data System (ADS)

    Zhang, L.; Zhang, M.; Liu, X.

    2016-05-01

    CLEAN algorithms are a class of deconvolution solvers which are widely used to remove the effect of the telescope Point Spread Function (PSF). Loop gain is one important parameter in CLEAN algorithms. Currently the parameter is fixed during deconvolution, which restricts the performance of CLEAN algorithms. In this paper, we propose a new deconvolution algorithm with an adaptive loop gain scheme, which is referred to as the adaptive-loop-gain adaptive-scale CLEAN (Algas-Clean) algorithm. The test results show that the new algorithm can give a more accurate model with faster convergence.

  15. Loop transformations to prevent false sharing

    SciTech Connect

    Granston, E.D.; Montaut, T.; Bodin, F.

    1995-08-01

    To date, page management in shared virtual memory (SVM) systems has been primarily the responsibility of the run-time system. However, there are some problems that are difficult to resolve efficiently at run time. Chief among these is false sharing. In this paper, a loop transformation theory is developed for identifying and eliminating potential sources of multiple-writer false sharing and other sources of page migration resulting from regular references in numerical applications. Loop nests of one and two dimensions (before blocking) with single-level, DOALL-style parallelism are covered. The potential of these transformations is demonstrated experimentally.

  16. Kinematic calibration of manipulators with closed loop actuated joints

    NASA Technical Reports Server (NTRS)

    Everett, Louis J.; Lin, C. Y.

    1988-01-01

    A method for performing forward kinematic calibration of manipulators having one or more closed-loop-actuated joints is presented. The technique is an extension of algorithms designed for open-loop jointed manipulators. The calibration is equivalent to minimizing an objective function subject to constraints. The objective function is taken as the integral of end-effector position and orientation error. The constraints arise from the closed-loop mechanisms present in the manipulator.

  17. Algorithmic chemistry

    SciTech Connect

    Fontana, W.

    1990-12-13

    In this paper complex adaptive systems are defined by a self- referential loop in which objects encode functions that act back on these objects. A model for this loop is presented. It uses a simple recursive formal language, derived from the lambda-calculus, to provide a semantics that maps character strings into functions that manipulate symbols on strings. The interaction between two functions, or algorithms, is defined naturally within the language through function composition, and results in the production of a new function. An iterated map acting on sets of functions and a corresponding graph representation are defined. Their properties are useful to discuss the behavior of a fixed size ensemble of randomly interacting functions. This function gas'', or Turning gas'', is studied under various conditions, and evolves cooperative interaction patterns of considerable intricacy. These patterns adapt under the influence of perturbations consisting in the addition of new random functions to the system. Different organizations emerge depending on the availability of self-replicators.

  18. Loop Invariants, Exploration of Regularities, and Mathematical Games.

    ERIC Educational Resources Information Center

    Ginat, David

    2001-01-01

    Presents an approach for illustrating, on an intuitive level, the significance of loop invariants for algorithm design and analysis. The illustration is based on mathematical games that require the exploration of regularities via problem-solving heuristics. (Author/MM)

  19. Robust tuning of two-loop automatic control systems

    NASA Astrophysics Data System (ADS)

    Smirnov, N. I.; Sabanin, V. R.; Repin, A. I.

    2007-07-01

    We propose a solution to the problem of finding trade-off robust tuning parameters for two-loop automatic control systems by means of a numerical simulation method using the authors’ version of the Optim-MGA evolutionary optimization algorithm. Results from calculating and analyzing a two-loop superheated steam temperature control system employing a PI controller and a differentiator are presented.

  20. Resolving thermoelectric "paradox" in superconductors.

    PubMed

    Shelly, Connor D; Matrozova, Ekaterina A; Petrashov, Victor T

    2016-02-01

    For almost a century, thermoelectricity in superconductors has been one of the most intriguing topics in physics. During its early stages in the 1920s, the mere existence of thermoelectric effects in superconductors was questioned. In 1944, it was demonstrated that the effects may occur in inhomogeneous superconductors. Theoretical breakthrough followed in the 1970s, when the generation of a measurable thermoelectric magnetic flux in superconducting loops was predicted; however, a major crisis developed when experiments showed puzzling discrepancies with the theory. Moreover, different experiments were inconsistent with each other. This led to a stalemate in bringing theory and experiment into agreement. With this work, we resolve this stalemate, thus solving this long-standing "paradox," and open prospects for exploration of novel thermoelectric phenomena predicted recently. PMID:26933688

  1. Loops and trees

    NASA Astrophysics Data System (ADS)

    Caron-Huot, S.

    2011-05-01

    We investigate relations between loop and tree amplitudes in quantum field theory that involve putting on-shell some loop propagators. This generalizes the so-called Feynman tree theorem which is satisfied at 1-loop. Exploiting retarded boundary conditions, we give a generalization to ℓ-loop expressing the loops as integrals over the on-shell phase space of exactly ℓ particles. We argue that the corresponding integrand for ℓ > 2 does not involve the forward limit of any physical tree amplitude, except in planar gauge theories. In that case we explicitly construct the relevant physical amplitude. Beyond the planar limit, abandoning direct integral representations, we propose that loops continue to be determined implicitly by the forward limit of physical connected trees, and we formulate a precise conjecture along this line. Finally, we set up technology to compute forward amplitudes in supersymmetric theories, in which specific simplifications occur.

  2. Improved multiprocessor garbage collection algorithms

    SciTech Connect

    Newman, I.A.; Stallard, R.P.; Woodward, M.C.

    1983-01-01

    Outlines the results of an investigation of existing multiprocessor garbage collection algorithms and introduces two new algorithms which significantly improve some aspects of the performance of their predecessors. The two algorithms arise from different starting assumptions. One considers the case where the algorithm will terminate successfully whatever list structure is being processed and assumes that the extra data space should be minimised. The other seeks a very fast garbage collection time for list structures that do not contain loops. Results of both theoretical and experimental investigations are given to demonstrate the efficacy of the algorithms. 7 references.

  3. Laminated BEAM loops

    NASA Astrophysics Data System (ADS)

    Danisch, Lee A.

    1996-10-01

    BEAM sensors include treated loops of optical fiber that modulate optical throughput with great sensitivity and linearity, in response to curvature of the loop out of its plane. This paper describes BEAM sensors that have two loops treated in opposed fashion, hermetically sealed in flexible laminations. The sensors include an integrated optoelectronics package that extracts curvature information from the treated portion of the loops while rejecting common mode errors. The laminated structure is used to sense various parameters including displacement, force, pressure, flow, and acceleration.

  4. Observational Evidence for Loop-Loop Interaction

    NASA Astrophysics Data System (ADS)

    Guiping, W.; Guangli, H.; Yuhua, T.; Aoao, X.

    2004-01-01

    Through analysis of the data including the hard x-ray(BASTE) microwave(NoRP) and magnetogram(MDI from SOHO) as well as the images of soft x-ray(YHKOH) and EIT(SOHO) on Apr. 151998 solar flare in the active region 8203(N30W12) we found: (1) there are similar quasi period oscillation in the profile of hard x-ray flux (25-5050-100keV) and microwave flux(1GHz) with duration of 85+/-25s every peak includes two sub-peak structures; (2) in the preheat phase of the flare active magnetic field changes apparently and a s-pole spot emerges ; (3) several EIT and soft x-ray loops exist and turn into bright . All of these may suggest that loop-loop interaction indeed exist. Through reconnection the electrons may be accelerated and the hard x-ray and microwave emission take place.

  5. Generalized directed loop method for quantum Monte Carlo simulations.

    PubMed

    Alet, Fabien; Wessel, Stefan; Troyer, Matthias

    2005-03-01

    Efficient quantum Monte Carlo update schemes called directed loops have recently been proposed, which improve the efficiency of simulations of quantum lattice models. We propose to generalize the detailed balance equations at the local level during the loop construction by accounting for the matrix elements of the operators associated with open world-line segments. Using linear programming techniques to solve the generalized equations, we look for optimal construction schemes for directed loops. This also allows for an extension of the directed loop scheme to general lattice models, such as high-spin or bosonic models. The resulting algorithms are bounce free in larger regions of parameter space than the original directed loop algorithm. The generalized directed loop method is applied to the magnetization process of spin chains in order to compare its efficiency to that of previous directed loop schemes. In contrast to general expectations, we find that minimizing bounces alone does not always lead to more efficient algorithms in terms of autocorrelations of physical observables, because of the nonuniqueness of the bounce-free solutions. We therefore propose different general strategies to further minimize autocorrelations, which can be used as supplementary requirements in any directed loop scheme. We show by calculating autocorrelation times for different observables that such strategies indeed lead to improved efficiency; however, we find that the optimal strategy depends not only on the model parameters but also on the observable of interest. PMID:15903632

  6. Intrinsic flexibility of snRNA hairpin loops facilitates protein binding.

    PubMed

    Rau, Michael; Stump, W Tom; Hall, Kathleen B

    2012-11-01

    Stem-loop II of U1 snRNA and Stem-loop IV of U2 snRNA typically have 10 or 11 nucleotides in their loops. The fluorescent nucleobase 2-aminopurine was used as a substitute for the adenines in each loop to probe the local and global structures and dynamics of these unusually long loops. Using steady-state and time-resolved fluorescence, we find that, while the bases in the loops are stacked, they are able to undergo significant local motion on the picosecond/nanosecond timescale. In addition, the loops have a global conformational change at low temperatures that occurs on the microsecond timescale, as determined using laser T-jump experiments. Nucleobase and loop motions are present at temperatures far below the melting temperature of the hairpin stem, which may facilitate the conformational change required for specific protein binding to these RNA loops. PMID:23012481

  7. Resolving the Pericenter

    NASA Astrophysics Data System (ADS)

    Wisdom, Jack

    2015-10-01

    The Wisdom-Holman mapping method and its variations have become a mainstay of research in solar system dynamics. But the method is not without its limitations. Rauch & Holman noted that at large eccentricities sufficiently small steps must be taken to resolve the pericenter. In this paper, I explore in more detail what it means to resolve the pericenter.

  8. Structure Prediction of RNA Loops with a Probabilistic Approach

    PubMed Central

    Li, Jun; Zhang, Jian; Wang, Jun; Li, Wenfei; Wang, Wei

    2016-01-01

    The knowledge of the tertiary structure of RNA loops is important for understanding their functions. In this work we develop an efficient approach named RNApps, specifically designed for predicting the tertiary structure of RNA loops, including hairpin loops, internal loops, and multi-way junction loops. It includes a probabilistic coarse-grained RNA model, an all-atom statistical energy function, a sequential Monte Carlo growth algorithm, and a simulated annealing procedure. The approach is tested with a dataset including nine RNA loops, a 23S ribosomal RNA, and a large dataset containing 876 RNAs. The performance is evaluated and compared with a homology modeling based predictor and an ab initio predictor. It is found that RNApps has comparable performance with the former one and outdoes the latter in terms of structure predictions. The approach holds great promise for accurate and efficient RNA tertiary structure prediction. PMID:27494763

  9. Structure Prediction of RNA Loops with a Probabilistic Approach.

    PubMed

    Li, Jun; Zhang, Jian; Wang, Jun; Li, Wenfei; Wang, Wei

    2016-08-01

    The knowledge of the tertiary structure of RNA loops is important for understanding their functions. In this work we develop an efficient approach named RNApps, specifically designed for predicting the tertiary structure of RNA loops, including hairpin loops, internal loops, and multi-way junction loops. It includes a probabilistic coarse-grained RNA model, an all-atom statistical energy function, a sequential Monte Carlo growth algorithm, and a simulated annealing procedure. The approach is tested with a dataset including nine RNA loops, a 23S ribosomal RNA, and a large dataset containing 876 RNAs. The performance is evaluated and compared with a homology modeling based predictor and an ab initio predictor. It is found that RNApps has comparable performance with the former one and outdoes the latter in terms of structure predictions. The approach holds great promise for accurate and efficient RNA tertiary structure prediction. PMID:27494763

  10. Loops and multiple edges in modularity maximization of networks

    NASA Astrophysics Data System (ADS)

    Cafieri, Sonia; Hansen, Pierre; Liberti, Leo

    2010-04-01

    The modularity maximization model proposed by Newman and Girvan for the identification of communities in networks works for general graphs possibly with loops and multiple edges. However, the applications usually correspond to simple graphs. These graphs are compared to a null model where the degree distribution is maintained but edges are placed at random. Therefore, in this null model there will be loops and possibly multiple edges. Sharp bounds on the expected number of loops, and their impact on the modularity, are derived. Then, building upon the work of Massen and Doye, but using algebra rather than simulation, we propose modified null models associated with graphs without loops but with multiple edges, graphs with loops but without multiple edges and graphs without loops nor multiple edges. We validate our models by using the exact algorithm for clique partitioning of Grötschel and Wakabayashi.

  11. Resolution of curvature singularities from quantum mechanical and loop perspective

    NASA Astrophysics Data System (ADS)

    Tahamtan, T.; Svítek, O.

    2014-08-01

    We analyze the persistence of curvature singularities when analyzed using quantum theory. First, quantum test particles obeying the Klein-Gordon and Chandrasekhar-Dirac equation are used to probe the classical timelike naked singularity. We show that the classical singularity is felt even by our quantum probes. Next, we use loop quantization to resolve a singularity hidden beneath the horizon. The singularity is resolved in this case.

  12. Thermal power loops

    NASA Technical Reports Server (NTRS)

    Gottschlich, Joseph M.; Richter, Robert

    1991-01-01

    The concept of a thermal power loop (TPL) to transport thermal power over relatively large distances is presented as an alternative to heat pipes and their derivatives. The TPL is compared to heat pipes, and capillary pumped loops with respect to size, weight, conservation of thermal potential, start-up, and 1-g testing capability. Test results from a proof of feasibility demonstrator at the NASA JPL are discussed. This analysis demonstrates that the development of specific thermal power loops will result in substantial weight and cost savings for many spacecraft.

  13. Whisker weaving: Invalid connectivity resolution and primal construction algorithm

    SciTech Connect

    Tautgas, T.J.; Mitchell, S.A.

    1995-11-01

    This paper describes the techniques used to resolve invalid connectivity created as a natural part of the whisker weaving algorithm. These techniques rely on the detection of {open_quotes}repeated hexes{close_quotes} in the STC data, which indicate face pairs which share two edges. The {open_quotes}repeated hex{close_quotes} case is described in detail, including the resolution technique by which a self-intersecting whisker sheet with two independent face loops are created. The algorithm used to construct the primal of an all-hexahedral mesh (i.e. the actual nodes and hex elements) from the connectivity data contained in the STC is also described. The primal is constructed using a {open_quotes}gift-wrapping{close_quotes} algorithm, where all the mesh edges and hexes containing a particular node are found by traversing between hexes already known to share the node. This algorithm is implemented inside the CUBIT code and is used to generate meshes for several example problems.

  14. Interstitial loop transformations in FeCr

    DOE PAGESBeta

    Béland, Laurent Karim; Osetsky, Yuri N.; Stoller, Roger E.; Xu, Haixuan

    2015-03-27

    Here, we improve the Self-Evolving Atomistic Kinetic Monte Carlo (SEAKMC) algorithm by integrating the Activation Relaxation Technique nouveau (ARTn), a powerful open-ended saddle-point search method, into the algorithm. We use it to investigate the reaction of 37-interstitial 1/2[1 1 1] and 1/2[View the MathML source] loops in FeCr at 10 at.% Cr. They transform into 1/2[1 1 1], 1/2[View the MathML source], [1 0 0] and [0 1 0] 74-interstitial clusters with an overall barrier of 0.85 eV. We find that Cr decoration locally inhibits the rotation of crowdions, which dictates the final loop orientation. Moreover, the final loop orientationmore » depends on the details of the Cr decoration. Generally, a region of a given orientation is favored if Cr near its interface with a region of another orientation is able to inhibit reorientation at this interface more than the Cr present at the other interfaces. Also, we find that substitutional Cr atoms can diffuse from energetically unfavorable to energetically favorable sites within the interlocked 37-interstitial loops conformation with barriers of less than 0.35 eV.« less

  15. Interstitial loop transformations in FeCr

    SciTech Connect

    Béland, Laurent Karim; Osetsky, Yuri N.; Stoller, Roger E.; Xu, Haixuan

    2015-03-27

    Here, we improve the Self-Evolving Atomistic Kinetic Monte Carlo (SEAKMC) algorithm by integrating the Activation Relaxation Technique nouveau (ARTn), a powerful open-ended saddle-point search method, into the algorithm. We use it to investigate the reaction of 37-interstitial 1/2[1 1 1] and 1/2[View the MathML source] loops in FeCr at 10 at.% Cr. They transform into 1/2[1 1 1], 1/2[View the MathML source], [1 0 0] and [0 1 0] 74-interstitial clusters with an overall barrier of 0.85 eV. We find that Cr decoration locally inhibits the rotation of crowdions, which dictates the final loop orientation. Moreover, the final loop orientation depends on the details of the Cr decoration. Generally, a region of a given orientation is favored if Cr near its interface with a region of another orientation is able to inhibit reorientation at this interface more than the Cr present at the other interfaces. Also, we find that substitutional Cr atoms can diffuse from energetically unfavorable to energetically favorable sites within the interlocked 37-interstitial loops conformation with barriers of less than 0.35 eV.

  16. Natively Unstructured Loops Differ from Other Loops

    PubMed Central

    Schlessinger, Avner; Liu, Jinfeng; Rost, Burkhard

    2007-01-01

    Natively unstructured or disordered protein regions may increase the functional complexity of an organism; they are particularly abundant in eukaryotes and often evade structure determination. Many computational methods predict unstructured regions by training on outliers in otherwise well-ordered structures. Here, we introduce an approach that uses a neural network in a very different and novel way. We hypothesize that very long contiguous segments with nonregular secondary structure (NORS regions) differ significantly from regular, well-structured loops, and that a method detecting such features could predict natively unstructured regions. Training our new method, NORSnet, on predicted information rather than on experimental data yielded three major advantages: it removed the overlap between testing and training, it systematically covered entire proteomes, and it explicitly focused on one particular aspect of unstructured regions with a simple structural interpretation, namely that they are loops. Our hypothesis was correct: well-structured and unstructured loops differ so substantially that NORSnet succeeded in their distinction. Benchmarks on previously used and new experimental data of unstructured regions revealed that NORSnet performed very well. Although it was not the best single prediction method, NORSnet was sufficiently accurate to flag unstructured regions in proteins that were previously not annotated. In one application, NORSnet revealed previously undetected unstructured regions in putative targets for structural genomics and may thereby contribute to increasing structural coverage of large eukaryotic families. NORSnet found unstructured regions more often in domain boundaries than expected at random. In another application, we estimated that 50%–70% of all worm proteins observed to have more than seven protein–protein interaction partners have unstructured regions. The comparative analysis between NORSnet and DISOPRED2 suggested that long

  17. Introduction to Loop Heat Pipes

    NASA Technical Reports Server (NTRS)

    Ku, Jentung

    2015-01-01

    This is the presentation file for the short course Introduction to Loop Heat Pipes, to be conducted at the 2015 Thermal Fluids and Analysis Workshop, August 3-7, 2015, Silver Spring, Maryland. This course will discuss operating principles and performance characteristics of a loop heat pipe. Topics include: 1) pressure profiles in the loop; 2) loop operating temperature; 3) operating temperature control; 4) loop startup; 4) loop shutdown; 5) loop transient behaviors; 6) sizing of loop components and determination of fluid inventory; 7) analytical modeling; 8) examples of flight applications; and 9) recent LHP developments.

  18. Modeling of protein loops by simulated annealing.

    PubMed Central

    Collura, V.; Higo, J.; Garnier, J.

    1993-01-01

    A method is presented to model loops of protein to be used in homology modeling of proteins. This method employs the ESAP program of Higo et al. (Higo, J., Collura, V., & Garnier, J., 1992, Biopolymers 32, 33-43) and is based on a fast Monte Carlo simulation and a simulated annealing algorithm. The method is tested on different loops or peptide segments from immunoglobulin, bovine pancreatic trypsin inhibitor, and bovine trypsin. The predicted structure is obtained from the ensemble average of the coordinates of the Monte Carlo simulation at 300 K, which exhibits the lowest internal energy. The starting conformation of the loop prior to modeling is chosen to be completely extended, and a closing harmonic potential is applied to N, CA, C, and O atoms of the terminal residues. A rigid geometry potential of Robson and Platt (1986, J. Mol. Biol. 188, 259-281) with a united atom representation is used. This we demonstrate to yield a loop structure with good hydrogen bonding and torsion angles in the allowed regions of the Ramachandran map. The average accuracy of the modeling evaluated on the eight modeled loops is 1 A root mean square deviation (rmsd) for the backbone atoms and 2.3 A rmsd for all heavy atoms. PMID:8401234

  19. Conformational Sampling in Template-Free Protein Loop Structure Modeling: An Overview

    PubMed Central

    Li, Yaohang

    2013-01-01

    Accurately modeling protein loops is an important step to predict three-dimensional structures as well as to understand functions of many proteins. Because of their high flexibility, modeling the three-dimensional structures of loops is difficult and is usually treated as a “mini protein folding problem” under geometric constraints. In the past decade, there has been remarkable progress in template-free loop structure modeling due to advances of computational methods as well as stably increasing number of known structures available in PDB. This mini review provides an overview on the recent computational approaches for loop structure modeling. In particular, we focus on the approaches of sampling loop conformation space, which is a critical step to obtain high resolution models in template-free methods. We review the potential energy functions for loop modeling, loop buildup mechanisms to satisfy geometric constraints, and loop conformation sampling algorithms. The recent loop modeling results are also summarized. PMID:24688696

  20. A Mirnov loop array for field-reversed configurations

    SciTech Connect

    Tuszewski, M.

    1990-01-01

    An array of 64 magnetic pick-up loops has been used for stability studies of large field-reversed configurations in the FRX-C/LSM device. This array proved reliable, could resolve signals of a few Gauss, and allowed the detection of several plasma instabilities. 3 refs., 4 figs.

  1. A Robustly Stabilizing Model Predictive Control Algorithm

    NASA Technical Reports Server (NTRS)

    Ackmece, A. Behcet; Carson, John M., III

    2007-01-01

    A model predictive control (MPC) algorithm that differs from prior MPC algorithms has been developed for controlling an uncertain nonlinear system. This algorithm guarantees the resolvability of an associated finite-horizon optimal-control problem in a receding-horizon implementation.

  2. The Fundamental Structure of Coronal Loops

    NASA Technical Reports Server (NTRS)

    Winebarger, Amy; Warren, Harry; Cirtain, Jonathan; Kobayashi, Ken; Korreck, Kelly; Golub, Leon; Kuzin, Sergey; Walsh, Robert; DePontieu, Bart; Title, Alan; Weber, Mark

    2012-01-01

    During the past ten years, solar physicists have attempted to infer the coronal heating mechanism by comparing observations of coronal loops with hydrodynamic model predictions. These comparisons often used the addition of sub ]resolution strands to explain the observed loop properties. On July 11, 2012, the High Resolution Coronal Imager (Hi ]C) was launched on a sounding rocket. This instrument obtained images of the solar corona was 0.2 ]0.3'' resolution in a narrowband EUV filter centered around 193 Angstroms. In this talk, we will compare these high resolution images to simultaneous density measurements obtained with the Extreme Ultraviolet Imaging Spectrograph (EIS) on Hinode to determine whether the structures observed with Hi ]C are resolved.

  3. Loop quantization of the Schwarzschild black hole.

    PubMed

    Gambini, Rodolfo; Pullin, Jorge

    2013-05-24

    We quantize spherically symmetric vacuum gravity without gauge fixing the diffeomorphism constraint. Through a rescaling, we make the algebra of Hamiltonian constraints Abelian, and therefore the constraint algebra is a true Lie algebra. This allows the completion of the Dirac quantization procedure using loop quantum gravity techniques. We can construct explicitly the exact solutions of the physical Hilbert space annihilated by all constraints. New observables living in the bulk appear at the quantum level (analogous to spin in quantum mechanics) that are not present at the classical level and are associated with the discrete nature of the spin network states of loop quantum gravity. The resulting quantum space-times resolve the singularity present in the classical theory inside black holes. PMID:23745855

  4. IRIS Resolving Unresolved Structure

    NASA Video Gallery

    NASA’s IRIS, which is able to look at a low layer of the sun’s atmosphere in unprecedented resolution, reveals details in the bright loops seen over the sun’s limb that have never been witnessed be...

  5. Efficient static scheduling of loops on synchronous multiprocessors

    SciTech Connect

    Zaky, A.M.

    1989-01-01

    This dissertation investigates efficient compile-time scheduling techniques for exploiting parallelism on synchronous multiprocessors. Synchronous multiprocessors, e.g. Very Long Instruction Word (VLIW) machines, are very effective in utilizing unstructured fine-grained parallelism in programs. The effectiveness of such machines is crucially dependent on the static compile-time analysis and detection of potential parallelism. The first part of the dissertation focuses on scheduling sequential loops on multiprocessors with multiple identical processor units. The problem of determining the maximal initiation rate for the execution of a sequential loop with uniform dependence distances on a synchronous multiprocessor is addressed and cast as an eigenvalue problem in a path algebra. A low-order polynomial algorithm for the determination of the optimal loop initiation rate is developed, and a schedule that exploits fine-grained parallelism and achieves the optimal initiation rate is developed under an idealized unbounded processor model. Next, the concepts developed above are extended to deal with perfectly-nested loops with uniform dependences. A strategy is developed to identify both the loop level and fine-grained expression level parallelism in nested loops, and to efficiently schedule such loops on synchronous multiprocessors. Loop scheduling techniques such as Do-Across, Wavefront scheduling, and fine-grained scheduling techniques such as loop unfolding are shown to be derivable within the presented framework.

  6. Multicenter Closed-Loop Insulin Delivery Study Points to Challenges for Keeping Blood Glucose in a Safe Range by a Control Algorithm in Adults and Adolescents with Type 1 Diabetes from Various Sites

    PubMed Central

    Zisser, Howard; Renard, Eric; Kovatchev, Boris; Cobelli, Claudio; Avogaro, Angelo; Nimri, Revital; Magni, Lalo; Buckingham, Bruce A.; Chase, H. Peter; Doyle, Francis J.; Lum, John; Calhoun, Peter; Kollman, Craig; Dassau, Eyal; Farret, Anne; Place, Jerome; Breton, Marc; Anderson, Stacey M.; Dalla Man, Chiara; Del Favero, Simone; Bruttomesso, Daniela; Filippi, Alessio; Scotton, Rachele; Phillip, Moshe; Atlas, Eran; Muller, Ido; Miller, Shahar; Toffanin, Chiara; Raimondo, Davide Martino; De Nicolao, Giuseppe

    2014-01-01

    Abstract Background: The Control to Range Study was a multinational artificial pancreas study designed to assess the time spent in the hypo- and hyperglycemic ranges in adults and adolescents with type 1 diabetes while under closed-loop control. The controller attempted to keep the glucose ranges between 70 and 180 mg/dL. A set of prespecified metrics was used to measure safety. Research Design and Methods: We studied 53 individuals for approximately 22 h each during clinical research center admissions. Plasma glucose level was measured every 15–30 min (YSI clinical laboratory analyzer instrument [YSI, Inc., Yellow Springs, OH]). During the admission, subjects received three mixed meals (1 g of carbohydrate/kg of body weight; 100 g maximum) with meal announcement and automated insulin dosing by the controller. Results: For adults, the mean of subjects' mean glucose levels was 159 mg/dL, and mean percentage of values 71–180 mg/dL was 66% overall (59% daytime and 82% overnight). For adolescents, the mean of subjects' mean glucose levels was 166 mg/dL, and mean percentage of values in range was 62% overall (53% daytime and 82% overnight). Whereas prespecified criteria for safety were satisfied by both groups, they were met at the individual level in adults only for combined daytime/nighttime and for isolated nighttime. Two adults and six adolescents failed to meet the daytime criterion, largely because of postmeal hyperglycemia, and another adolescent failed to meet the nighttime criterion. Conclusions: The control-to-range system performed as expected: faring better overnight than during the day and performing with variability between patients even after individualization based on patients' prior settings. The system had difficulty preventing postmeal excursions above target range. PMID:25003311

  7. Wilson-loop instantons

    NASA Technical Reports Server (NTRS)

    Lee, Kimyeong; Holman, Richard; Kolb, Edward W.

    1987-01-01

    Wilson-loop symmetry breaking is considered on a space-time of the form M4 x K, where M4 is a four-dimensional space-time and K is an internal space with nontrivial and finite fundamental group. It is shown in a simple model that the different vacua obtained by breaking a non-Abelian gauge group by Wilson loops are separated in the space of gauge potentials by a finite energy barrier. An interpolating gauge configuration is then constructed between these vacua and shown to have minimum energy. Finally some implications of this construction are discussed.

  8. Sarsat location algorithms

    NASA Astrophysics Data System (ADS)

    Nardi, Jerry

    The Satellite Aided Search and Rescue (Sarsat) is designed to detect and locate distress beacons using satellite receivers. Algorithms used for calculating the positions of 406 MHz beacons and 121.5/243 MHz beacons are presented. The techniques for matching, resolving and averaging calculated locations from multiple satellite passes are also described along with results pertaining to single pass and multiple pass location estimate accuracy.

  9. HIGH SPATIAL RESOLUTION OBSERVATIONS OF LOOPS IN THE SOLAR CORONA

    SciTech Connect

    Brooks, David H.; Ugarte-Urra, Ignacio; Warren, Harry P.; Winebarger, Amy R.

    2013-08-01

    Understanding how the solar corona is structured is of fundamental importance to determine how the Sun's upper atmosphere is heated to high temperatures. Recent spectroscopic studies have suggested that an instrument with a spatial resolution of 200 km or better is necessary to resolve coronal loops. The High Resolution Coronal Imager (Hi-C) achieved this performance on a rocket flight in 2012 July. We use Hi-C data to measure the Gaussian widths of 91 loops observed in the solar corona and find a distribution that peaks at about 270 km. We also use Atmospheric Imaging Assembly data for a subset of these loops and find temperature distributions that are generally very narrow. These observations provide further evidence that loops in the solar corona are often structured at a scale of several hundred kilometers, well above the spatial scale of many proposed physical mechanisms.

  10. Resolving Problems through Mediation.

    ERIC Educational Resources Information Center

    Notar, Susan

    1997-01-01

    Examines state variations in use of mediation to resolve domestic relations disputes. Mediation may be optional or mandatory, requested by the parties or the judge. Mediator qualifications vary considerably. Child support is less likely than custody and visitation to be the sole topic for mediation. More states are likely to use mediation in…

  11. Has Abstractness Been Resolved?

    ERIC Educational Resources Information Center

    Al-Omoush, Ahmad

    1989-01-01

    A discussion focusing on the abstractness of analysis in phonology, debated since the 1960s, describes the issue, reviews the literature on the subject, cites specific natural language examples, and examines the extent to which the issue has been resolved. An underlying representation is said to be abstract if it is different from the derived one,…

  12. Livermore Compiler Analysis Loop Suite

    2013-03-01

    LCALS is designed to evaluate compiler optimizations and performance of a variety of loop kernels and loop traversal software constructs. Some of the loop kernels are pulled directly from "Livermore Loops Coded in C", developed at LLNL (see item 11 below for details of earlier code versions). The older suites were used to evaluate floating-point performances of hardware platforms prior to porting larger application codes. The LCALS suite is geared toward assissing C++ compiler optimizationsmore » and platform performance related to SIMD vectorization, OpenMP threading, and advanced C++ language features. LCALS contains 20 of 24 loop kernels from the older Livermore Loop suites, plus various others representative of loops found in current production appkication codes at LLNL. The latter loops emphasize more diverse loop constructs and data access patterns than the others, such as multi-dimensional difference stencils. The loops are included in a configurable framework, which allows control of compilation, loop sampling for execution timing, which loops are run and their lengths. It generates timing statistics for analysis and comparing variants of individual loops. Also, it is easy to add loops to the suite as desired.« less

  13. Livermore Compiler Analysis Loop Suite

    SciTech Connect

    Hornung, R. D.

    2013-03-01

    LCALS is designed to evaluate compiler optimizations and performance of a variety of loop kernels and loop traversal software constructs. Some of the loop kernels are pulled directly from "Livermore Loops Coded in C", developed at LLNL (see item 11 below for details of earlier code versions). The older suites were used to evaluate floating-point performances of hardware platforms prior to porting larger application codes. The LCALS suite is geared toward assissing C++ compiler optimizations and platform performance related to SIMD vectorization, OpenMP threading, and advanced C++ language features. LCALS contains 20 of 24 loop kernels from the older Livermore Loop suites, plus various others representative of loops found in current production appkication codes at LLNL. The latter loops emphasize more diverse loop constructs and data access patterns than the others, such as multi-dimensional difference stencils. The loops are included in a configurable framework, which allows control of compilation, loop sampling for execution timing, which loops are run and their lengths. It generates timing statistics for analysis and comparing variants of individual loops. Also, it is easy to add loops to the suite as desired.

  14. Projection-resolved optical coherence tomographic angiography

    PubMed Central

    Zhang, Miao; Hwang, Thomas S.; Campbell, J. Peter; Bailey, Steven T.; Wilson, David J.; Huang, David; Jia, Yali

    2016-01-01

    Shadowgraphic projection artifacts from superficial vasculature interfere with the visualization of deeper vascular networks in optical coherence tomography angiography (OCT-A). We developed a novel algorithm to remove this artifact by resolving the ambiguity between in situ and projected flow signals. The algorithm identifies voxels with in situ flow as those where intensity-normalized decorrelation values are higher than all shallower voxels in the same axial scan line. This “projection-resolved” (PR) algorithm effectively suppressed the projection artifact on both en face and cross-sectional angiograms and enhanced depth resolution of vascular networks. In the human macula, the enhanced angiograms show three distinct vascular plexuses in the inner retina and no vessels in the outer retina. We demonstrate that PR OCT-A cleanly removes flow projection from the normally avascular outer retinal slab while preserving the density and continuity of the intermediate and deep retinal capillary plexuses. PMID:27231591

  15. NETL - Chemical Looping Reactor

    SciTech Connect

    2013-07-24

    NETL's Chemical Looping Reactor unit is a high-temperature integrated CLC process with extensive instrumentation to improve computational simulations. A non-reacting test unit is also used to study solids flow at ambient temperature. The CLR unit circulates approximately 1,000 pounds per hour at temperatures around 1,800 degrees Fahrenheit.

  16. NETL - Chemical Looping Reactor

    ScienceCinema

    None

    2014-06-26

    NETL's Chemical Looping Reactor unit is a high-temperature integrated CLC process with extensive instrumentation to improve computational simulations. A non-reacting test unit is also used to study solids flow at ambient temperature. The CLR unit circulates approximately 1,000 pounds per hour at temperatures around 1,800 degrees Fahrenheit.

  17. Loops: Twisting and Scaling

    NASA Astrophysics Data System (ADS)

    Walsh, R. W.

    2004-01-01

    Loop-like structures are the fundamental magnetic building blocks of the solar atmosphere. Recent space-based EUV and X-ray satellite observations (from Yohkoh SOHO and TRACE) have challenged the view that these features are simply static gravitationally stratified plasma pipes. Rather it is now surmised that each loop may consist of a bundle of fine plasma threads that are twisted around one another and can brighten independently. This invited review will outline the latest developments in ""untangling"" the topology of these features through three dimensional magnetohydrodynamic modelling and how their properties are being deduced through spectroscopic observations coupled to theoretical scaling laws. In particular recent interest has centred on how the observed thermal profile along loops can be employed as a tool to diagnose any localised energy input to the structure and hence constrain the presence of a particular coronal heating mechanism. The dynamic nature of loops will be highlighted and the implications of superior resolution plasma thread observations (whether spatial temporal or spectral) from future space missions (SolarB STEREO SDO and Solar Orbiter) will be discussed.

  18. RNA in the Loop

    PubMed Central

    Kung, Johnny T.Y.; Lee, Jeannie T.

    2013-01-01

    Long noncoding RNAs (lncRNAs) have been implicated in a variety of biological roles, particularly as cis or trans gene expression regulators. Reporting recently in Nature, Lai et al. (2013) show that a class of gene-activating lncRNAs combines two gene regulation paradigms: enhancer-directed chromosomal looping and RNA-mediated protein effector recruitment. PMID:23537627

  19. Closing the Loop Sampler.

    ERIC Educational Resources Information Center

    California Integrated Waste Management Board, Sacramento.

    Closing the Loop (CTL) is a science curriculum designed to introduce students to integrated waste management through awareness. This document presents five lesson plans focusing on developing an understanding of natural resources, solid wastes, conservation, and the life of landfills. Contents include: (1) "What Are Natural Resources?"; (2)…

  20. [Prediction of short loops in the proteins with internal disorder].

    PubMed

    Deriusheva, E I; Galzitskaia, O V; Serdiuk, I N

    2008-01-01

    New possibility of the FoldUnfold program for prediction of short disordered regions (loops), which appears by using the short window width (3 amino acid residues), was described. For three representatives of the proteins G family the FoldUnfold program predicted almost all short loops and yield results are well compatible with the X-ray structure data. We have classified the loops predicted in the protein Ras-p21 structure in two types. In the first type, loops have high values of the Debye-Waller factor typical of the so-called functional loops (flexible loops). In the other type, loops have lower values of the Debye-Waller factor and can be considered as loops connecting secondary structure elements (rigid loops). When the results of prediction with the use of our program are compared with the results of other programs (PONDR, RONN, DisEMBL, PreLINK, IUPred, GlobPlot 2, FoldIndex), it is seen that the first enables far better prediction of short loop positions. Use of FoldUnfold for ubiquitin-like domain h-PLIC-2 allows to resolve such task as definition of boundary between the structured and unstructured regions in proteins with a big portion of disordered regions. The FoldUnfold program defines a clear boundary between the structured and unstructured regions at amino acid residues 30-31,whereas each of the other programs outlines the boundary from the 28-th amino acid residues through the 70th. PMID:19140328

  1. 3D MHD Models of Active Region Loops

    NASA Technical Reports Server (NTRS)

    Ofman, Leon

    2004-01-01

    Present imaging and spectroscopic observations of active region loops allow to determine many physical parameters of the coronal loops, such as the density, temperature, velocity of flows in loops, and the magnetic field. However, due to projection effects many of these parameters remain ambiguous. Three dimensional imaging in EUV by the STEREO spacecraft will help to resolve the projection ambiguities, and the observations could be used to setup 3D MHD models of active region loops to study the dynamics and stability of active regions. Here the results of 3D MHD models of active region loops are presented, and the progress towards more realistic 3D MHD models of active regions. In particular the effects of impulsive events on the excitation of active region loop oscillations, and the generation, propagations and reflection of EIT waves are shown. It is shown how 3D MHD models together with 3D EUV observations can be used as a diagnostic tool for active region loop physical parameters, and to advance the science of the sources of solar coronal activity.

  2. Genetic algorithms

    NASA Technical Reports Server (NTRS)

    Wang, Lui; Bayer, Steven E.

    1991-01-01

    Genetic algorithms are mathematical, highly parallel, adaptive search procedures (i.e., problem solving methods) based loosely on the processes of natural genetics and Darwinian survival of the fittest. Basic genetic algorithms concepts are introduced, genetic algorithm applications are introduced, and results are presented from a project to develop a software tool that will enable the widespread use of genetic algorithm technology.

  3. Inferring Flare Loop Parameters with Measurements of Standing Sausage Modes

    NASA Astrophysics Data System (ADS)

    Guo, Ming-Zhe; Chen, Shao-Xia; Li, Bo; Xia, Li-Dong; Yu, Hui

    2016-03-01

    Standing fast sausage modes in flare loops were suggested to account for a considerable number of quasi-periodic pulsations (QPPs) in the light curves of solar flares. This study continues our investigation into the possibility of inverting the measured periods P and damping times τ of sausage modes to deduce the transverse Alfvén time R/v_{Ai}, density contrast ρi/ρe, and the steepness of the density distribution transverse to flare loops. A generic dispersion relation governing linear sausage modes is derived for pressureless cylinders where density inhomogeneity of arbitrary form takes place within the cylinder. We show that in general the inversion problem is under-determined for QPP events where only a single sausage mode exists, whether the measurements are spatially resolved or unresolved. While R/v_{Ai} can be inferred to some extent, the range of possible steepness parameters may be too broad to be useful. However, for spatially resolved measurements where an additional mode is present, it is possible to deduce self-consistently ρi/ρe, the profile steepness, and the internal Alfvén speed v_{Ai}. We show that at least for a recent QPP event that involves a fundamental kink mode in addition to a sausage one, flare loop parameters are well constrained even if the specific form of the transverse density distribution remains unknown. We conclude that spatially resolved, multi-mode QPP measurements need to be pursued to infer flare loop parameters.

  4. COLD TEST LOOP INTEGRATED TEST LOOP RESULTS

    SciTech Connect

    Abraham, TJ

    2003-10-22

    A testing facility (Cold Test Loop) was constructed and operated to demonstrate the efficacy of the Accelerated Waste Retrieval (AWR) Project's planned sluicing approach to the remediation of Silos 1 and 2 at the Fernald Environmental Management Project near Cincinnati, Ohio. The two silos contain almost 10,000 tons of radium-bearing low-level waste, which consists primarily of solids of raffinates from processing performed on ores from the Democratic Republic of Congo (commonly referred to as ''Belgium Congo ores'') for the recovery of uranium. These silos are 80 ft in diameter, 36 ft high to the center of the dome, and 26.75 ft to the top of the vertical side walls. The test facility contained two test systems, each designed for a specific purpose. The first system, the Integrated Test Loop (ITL), a near-full-scale plant including the actual equipment to be installed at the Fernald Site, was designed to demonstrate the sluicing operation and confirm the selection of a slurry pump, the optimal sluicing nozzle operation, and the preliminary design material balance. The second system, the Component Test Loop (CTL), was designed to evaluate many of the key individual components of the waste retrieval system over an extended run. The major results of the initial testing performed during July and August 2002 confirmed that the AWR approach to sluicing was feasible. The ITL testing confirmed the following: (1) The selected slurry pump (Hazleton 3-20 type SHW) performed well and is suitable for AWR application. However, the pump's motor should be upgraded to a 200-hp model and be driven by a 150-hp variable-frequency drive (VFD). A 200-hp VFD is not much more expensive and would allow the pump to operate at full speed. (2) The best nozzle performance was achieved by using 15/16-in. nozzles operated alternately. This configuration appeared to most effectively mine the surrogate. (3) The Solartron densitometer, which was tested as an alternative mass flow measurement

  5. The flow-chart loop: temperature, density, and cooling observables supporting nanoflare coronal heating models

    SciTech Connect

    Schmelz, J. T.; Pathak, S.; Dhaliwal, R. S.; Christian, G. M.; Fair, C. B.

    2014-11-10

    We have tested three controversial properties for a target loop observed with the Atmospheric Imaging Assembly: (1) overdense loops; (2) long-lifetime loops; and (3) multithermal loops. Our loop is overdense by a factor of about 10 compared to results expected from steady uniform heating models. If this were the only inconsistency, our loop could still be modeled as a single strand, but the density mismatch would imply that the heating must be impulsive. Moving on to the second observable, however, we find that the loop lifetime is at least an order of magnitude greater than the predicted cooling time. This implies that the loop cannot be composed of a single flux tube, even if the heating were dynamic, and must be multi-stranded. Finally, differential emission measure analysis shows that the cross-field temperature of the target loop is multithermal in the early and middle phases of its lifetime, but effectively isothermal before it fades from view. If these multithermal cooling results are found to be widespread, our results could resolve the original coronal loop controversy of 'isothermal' versus 'multithermal' cross-field temperatures. That is, the cross-field temperature is not always 'multithermal' nor is it always 'isothermal', but might change as the loop cools. We find that the existence and evolution of this loop is consistent with predictions of nanoflare heating.

  6. Adaptive Inner-Loop Rover Control

    NASA Technical Reports Server (NTRS)

    Kulkarni, Nilesh; Ippolito, Corey; Krishnakumar, Kalmanje; Al-Ali, Khalid M.

    2006-01-01

    Adaptive control technology is developed for the inner-loop speed and steering control of the MAX Rover. MAX, a CMU developed rover, is a compact low-cost 4-wheel drive, 4-wheel steer (double Ackerman), high-clearance agile durable chassis, outfitted with sensors and electronics that make it ideally suited for supporting research relevant to intelligent teleoperation and as a low-cost autonomous robotic test bed and appliance. The design consists of a feedback linearization based controller with a proportional - integral (PI) feedback that is augmented by an online adaptive neural network. The adaptation law has guaranteed stability properties for safe operation. The control design is retrofit in nature so that it fits inside the outer-loop path planning algorithms. Successful hardware implementation of the controller is illustrated for several scenarios consisting of actuator failures and modeling errors in the nominal design.

  7. Molecular motor driven transportation on microtubule loops

    NASA Astrophysics Data System (ADS)

    Sikora, Aurelien; Federici, Filippo; Kim, Kyongwan; Nakazawa, Hikaru; Umetsu, Mitsuo; Hwang, Wonmuk; Teizer, Winfried

    2015-03-01

    Molecular motors such as kinesin are naturally fitted for the transport of cargo. By offering an unlimited path, microtubule loops allow the study of kinesin motility on distances exceeding that offered by a single microtubule. Moreover, the periodicity of the path allows the comparisons of trajectories between laps. Here we study the motility of quantum dot labeled kinesin on microtubule loops. Motility of kinesins over multiple laps is observed and their trajectories are extracted from kymograph using a custom algorithm. Distribution of velocities at given locations do not vary randomly but show a correlation with the presence of obstacles. Possible mechanisms responsible for the long range transport are discussed in the context of available theories.

  8. Portable Health Algorithms Test System

    NASA Technical Reports Server (NTRS)

    Melcher, Kevin J.; Wong, Edmond; Fulton, Christopher E.; Sowers, Thomas S.; Maul, William A.

    2010-01-01

    A document discusses the Portable Health Algorithms Test (PHALT) System, which has been designed as a means for evolving the maturity and credibility of algorithms developed to assess the health of aerospace systems. Comprising an integrated hardware-software environment, the PHALT system allows systems health management algorithms to be developed in a graphical programming environment, to be tested and refined using system simulation or test data playback, and to be evaluated in a real-time hardware-in-the-loop mode with a live test article. The integrated hardware and software development environment provides a seamless transition from algorithm development to real-time implementation. The portability of the hardware makes it quick and easy to transport between test facilities. This hard ware/software architecture is flexible enough to support a variety of diagnostic applications and test hardware, and the GUI-based rapid prototyping capability is sufficient to support development execution, and testing of custom diagnostic algorithms. The PHALT operating system supports execution of diagnostic algorithms under real-time constraints. PHALT can perform real-time capture and playback of test rig data with the ability to augment/ modify the data stream (e.g. inject simulated faults). It performs algorithm testing using a variety of data input sources, including real-time data acquisition, test data playback, and system simulations, and also provides system feedback to evaluate closed-loop diagnostic response and mitigation control.

  9. Inner mappings of Bruck loops

    NASA Astrophysics Data System (ADS)

    Kreuzer, Alexander

    1998-01-01

    K-loops have their origin in the theory of sharply 2-transitive groups. In this paper a proof is given that K-loops and Bruck loops are the same. For the proof it is necessary to show that in a (left) Bruck loop the left inner mappings L(b)L(a) L(ab)[minus sign]1 are automorphisms. This paper generalizes results of Glauberman [3], Kist [8] and Kreuzer [9].

  10. Control algorithm implementation for a redundant degree of freedom manipulator

    NASA Technical Reports Server (NTRS)

    Cohan, Steve

    1991-01-01

    This project's purpose is to develop and implement control algorithms for a kinematically redundant robotic manipulator. The manipulator is being developed concurrently by Odetics Inc., under internal research and development funding. This SBIR contract supports algorithm conception, development, and simulation, as well as software implementation and integration with the manipulator hardware. The Odetics Dexterous Manipulator is a lightweight, high strength, modular manipulator being developed for space and commercial applications. It has seven fully active degrees of freedom, is electrically powered, and is fully operational in 1 G. The manipulator consists of five self-contained modules. These modules join via simple quick-disconnect couplings and self-mating connectors which allow rapid assembly/disassembly for reconfiguration, transport, or servicing. Each joint incorporates a unique drive train design which provides zero backlash operation, is insensitive to wear, and is single fault tolerant to motor or servo amplifier failure. The sensing system is also designed to be single fault tolerant. Although the initial prototype is not space qualified, the design is well-suited to meeting space qualification requirements. The control algorithm design approach is to develop a hierarchical system with well defined access and interfaces at each level. The high level endpoint/configuration control algorithm transforms manipulator endpoint position/orientation commands to joint angle commands, providing task space motion. At the same time, the kinematic redundancy is resolved by controlling the configuration (pose) of the manipulator, using several different optimizing criteria. The center level of the hierarchy servos the joints to their commanded trajectories using both linear feedback and model-based nonlinear control techniques. The lowest control level uses sensed joint torque to close torque servo loops, with the goal of improving the manipulator dynamic behavior

  11. Loop Heat Pipes and Capillary Pumped Loops: An Applications Perspective

    NASA Technical Reports Server (NTRS)

    Butler, Dan; Ku, Jentung; Swanson, Theodore; Obenschain, Arthur F. (Technical Monitor)

    2001-01-01

    Capillary pumped loops (CPLS) and loop heat pipes (LHPS) are versatile two-phase heat transfer devices which have recently gained increasing acceptance in space applications. Both systems work based on the same principles and have very similar designs. Nevertheless, some differences exist in the construction of the evaporator and the hydro-accumulator, and these differences lead to very distinct operating characteristics for each loop. This paper presents comparisons of the two loops from an applications perspective, and addresses their impact on spacecraft design, integration, and test. Some technical challenges and issues for both loops are also addressed.

  12. Cygnus Loop Supernova Blast Wave

    NASA Technical Reports Server (NTRS)

    1993-01-01

    This is an image of a small portion of the Cygnus Loop supernova remnant, which marks the edge of a bubble-like, expanding blast wave from a colossal stellar explosion, occurring about 15,000 years ago. The HST image shows the structure behind the shock waves, allowing astronomers for the first time to directly compare the actual structure of the shock with theoretical model calculations. Besides supernova remnants, these shock models are important in understanding a wide range of astrophysical phenomena, from winds in newly-formed stars to cataclysmic stellar outbursts. The supernova blast is slamming into tenuous clouds of insterstellar gas. This collision heats and compresses the gas, causing it to glow. The shock thus acts as a searchlight revealing the structure of the interstellar medium. The detailed HST image shows the blast wave overrunning dense clumps of gas, which despite HST's high resolution, cannot be resolved. This means that the clumps of gas must be small enough to fit inside our solar system, making them relatively small structures by interstellar standards. A bluish ribbon of light stretching left to right across the picture might be a knot of gas ejected by the supernova; this interstellar 'bullet' traveling over three million miles per hour (5 million kilometres) is just catching up with the shock front, which has slowed down by ploughing into interstellar material. The Cygnus Loop appears as a faint ring of glowing gases about three degrees across (six times the diameter of the full Moon), located in the northern constellation, Cygnus the Swan. The supernova remnant is within the plane of our Milky Way galaxy and is 2,600 light-years away. The photo is a combination of separate images taken in three colors, oxygen atoms (blue) emit light at temperatures of 30,000 to 60,000 degrees Celsius (50,000 to 100,000 degrees Farenheit). Hydrogen atoms (green) arise throughout the region of shocked gas. Sulfur atoms (red) form when the gas cools to

  13. Verification of Loop Diagnostics

    NASA Technical Reports Server (NTRS)

    Winebarger, A.; Lionello, R.; Mok, Y.; Linker, J.; Mikic, Z.

    2014-01-01

    Many different techniques have been used to characterize the plasma in the solar corona: density-sensitive spectral line ratios are used to infer the density, the evolution of coronal structures in different passbands is used to infer the temperature evolution, and the simultaneous intensities measured in multiple passbands are used to determine the emission measure. All these analysis techniques assume that the intensity of the structures can be isolated through background subtraction. In this paper, we use simulated observations from a 3D hydrodynamic simulation of a coronal active region to verify these diagnostics. The density and temperature from the simulation are used to generate images in several passbands and spectral lines. We identify loop structures in the simulated images and calculate the loop background. We then determine the density, temperature and emission measure distribution as a function of time from the observations and compare with the true temperature and density of the loop. We find that the overall characteristics of the temperature, density, and emission measure are recovered by the analysis methods, but the details of the true temperature and density are not. For instance, the emission measure curves calculated from the simulated observations are much broader than the true emission measure distribution, though the average temperature evolution is similar. These differences are due, in part, to inadequate background subtraction, but also indicate a limitation of the analysis methods.

  14. Chemical Looping Combustion Kinetics

    SciTech Connect

    Edward Eyring; Gabor Konya

    2009-03-31

    One of the most promising methods of capturing CO{sub 2} emitted by coal-fired power plants for subsequent sequestration is chemical looping combustion (CLC). A powdered metal oxide such as NiO transfers oxygen directly to a fuel in a fuel reactor at high temperatures with no air present. Heat, water, and CO{sub 2} are released, and after H{sub 2}O condensation the CO{sub 2} (undiluted by N{sub 2}) is ready for sequestration, whereas the nickel metal is ready for reoxidation in the air reactor. In principle, these processes can be repeated endlessly with the original nickel metal/nickel oxide participating in a loop that admits fuel and rejects ash, heat, and water. Our project accumulated kinetic rate data at high temperatures and elevated pressures for the metal oxide reduction step and for the metal reoxidation step. These data will be used in computational modeling of CLC on the laboratory scale and presumably later on the plant scale. The oxygen carrier on which the research at Utah is focused is CuO/Cu{sub 2}O rather than nickel oxide because the copper system lends itself to use with solid fuels in an alternative to CLC called 'chemical looping with oxygen uncoupling' (CLOU).

  15. Loops of Jupiter

    NASA Astrophysics Data System (ADS)

    Opolski, Antoni

    2014-12-01

    Professor Antoni Opolski was actively interested in astronomy after his retirement in 1983. He especially liked to study the works of the famous astronomer Copernicus getting inspiration for his own work. Opolski started his work on planetary loops in 2011 continuing it to the end of 2012 . During this period calculations, drawings, tables, and basic descriptions of all the planets of the Solar System were created with the use of a piece of paper and a pencil only. In 2011 Antoni Opolski asked us to help him in editing the manuscript and preparing it for publication. We have been honored having the opportunity to work on articles on planetary loops with Antoni Opolski in his house for several months. In the middle of 2012 the detailed material on Jupiter was ready. However, professor Opolski improved the article by smoothing the text and preparing new, better drawings. Finally the article ''Loops of Jupiter'', written by the 99- year old astronomer, was published in the year of his 100th birthday.

  16. Mapping algorithms on regular parallel architectures

    SciTech Connect

    Lee, P.

    1989-01-01

    It is significant that many of time-intensive scientific algorithms are formulated as nested loops, which are inherently regularly structured. In this dissertation the relations between the mathematical structure of nested loop algorithms and the architectural capabilities required for their parallel execution are studied. The architectural model considered in depth is that of an arbitrary dimensional systolic array. The mathematical structure of the algorithm is characterized by classifying its data-dependence vectors according to the new ZERO-ONE-INFINITE property introduced. Using this classification, the first complete set of necessary and sufficient conditions for correct transformation of a nested loop algorithm onto a given systolic array of an arbitrary dimension by means of linear mappings is derived. Practical methods to derive optimal or suboptimal systolic array implementations are also provided. The techniques developed are used constructively to develop families of implementations satisfying various optimization criteria and to design programmable arrays efficiently executing classes of algorithms. In addition, a Computer-Aided Design system running on SUN workstations has been implemented to help in the design. The methodology, which deals with general algorithms, is illustrated by synthesizing linear and planar systolic array algorithms for matrix multiplication, a reindexed Warshall-Floyd transitive closure algorithm, and the longest common subsequence algorithm.

  17. Semi-numerical evaluation of one-loop corrections

    SciTech Connect

    Ellis, R.K.; Giele, W.T.; Zanderighi, G.; /Fermilab

    2005-08-01

    We present a semi-numerical algorithm to calculate one-loop virtual corrections to scattering amplitudes. The divergences of the loop amplitudes are regulated using dimensional regularization. We treat in detail the case of amplitudes with up to five external legs and massless internal lines, although the method is more generally applicable. Tensor integrals are reduced to generalized scalar integrals, which in turn are reduced to a set of known basis integrals using recursion relations. The reduction algorithm is modified near exceptional configurations to ensure numerical stability. To test the procedure we apply these techniques to one-loop corrections to the Higgs to four quark process for which analytic results have recently become available.

  18. FORTE hardware-in-loop simulation

    SciTech Connect

    Ruud, K.K.; Murray, H.S.; Moore, T.K.

    1997-12-01

    Fast On-Orbit Recording of Transient Events (FORTE) is a small, low Earth orbit satellite scheduled for launch in August 1997. FORTE is a momentum-biased, gravity-gradient stabilized spacecraft. This paper describes the use of a hardware-in-loop simulator, developed by Ithaco Inc. and Los Alamos National Laboratory, in performing FORTE mission simulations. Scenarios studied include separation, acquisition on orbit, control system parameter sensitivity studies, sensor noise simulations, antenna deployment and momentum desaturation. Use of the simulator to refine control algorithms and sequences is also described.

  19. Loops in Reeb Graphs of 2-Manifolds

    SciTech Connect

    Cole-McLaughlin, K; Edelsbrunner, H; Harer, J; Natarajan, V; Pascucci, V

    2004-12-16

    Given a Morse function f over a 2-manifold with or without boundary, the Reeb graph is obtained by contracting the connected components of the level sets to points. We prove tight upper and lower bounds on the number of loops in the Reeb graph that depend on the genus, the number of boundary components, and whether or not the 2-manifold is orientable. We also give an algorithm that constructs the Reeb graph in time O(n log n), where n is the number of edges in the triangulation used to represent the 2-manifold and the Morse function.

  20. Loops in Reeb Graphs of 2-Manifolds

    SciTech Connect

    Cole-McLaughlin, K; Edelsbrunner, H; Harer, J; Natarajan, V; Pascucci, V

    2003-02-11

    Given a Morse function f over a 2-manifold with or without boundary, the Reeb graph is obtained by contracting the connected components of the level sets to points. We prove tight upper and lower bounds on the number of loops in the Reeb graph that depend on the genus, the number of boundary components, and whether or not the 2-manifold is orientable. We also give an algorithm that constructs the Reeb graph in time O(n log n), where n is the number of edges in the triangulation used to represent the 2-manifold and the Morse function.

  1. Small Body GN&C Research Report: A Guidance and Control Technique for Small-Body Proximity Operations with Guaranteed Guidance Resolvability and Required Thruster Silent Time

    NASA Technical Reports Server (NTRS)

    Carson, John M., III; Ackmese, A. Behcet

    2005-01-01

    The guidance and control (G&C) algorithms for enabling small-body proximity operations are developed by using a model predictive control approach along with a convexification of the governing dynamics, control constraints, and trajectory/state constraints. The open-loop guidance is solved ahead of time or in a resolvable, real-time manner through the use of PWG (Pseudo Way-point Generation), a technique developed in this research. The PWG scheme ensures required thruster silent times during trajectory maneuvers. The feedback control is implemented to track the PWG trajectories in a manner that guarantees the resolvability for the open-loop problem, enabling the ability to update the G&C in a model-predictive manner. The schemes incorporate gravity models and thruster ring times into discrete dynamics that are solved as a optimal control problem to minimize fuel consumption or thruster energy expenditure. The optimal control problem is cast as an LMI (Linear Matrix Inequality) and then solved through Semi-Definite Programming techniques in a computationally efficient manner that provides convergence and constraint guarantees.

  2. Resource Prospector: The RESOLVE Payload

    NASA Astrophysics Data System (ADS)

    Quinn, J.; Smith, J.; J., Captain; Paz, A.; Colaprete, A.; Elphic, R.; Zacny, K.

    2015-10-01

    NASA has been developing a lunar volatiles exploration payload named RESOLVE. Now the primary science payload on-board the Resource Prospector (RP) mission, RESOLVE, consists of several instruments that evaluate lunar volatiles.

  3. Automatic numerical integration methods for Feynman integrals through 3-loop

    NASA Astrophysics Data System (ADS)

    de Doncker, E.; Yuasa, F.; Kato, K.; Ishikawa, T.; Olagbemi, O.

    2015-05-01

    We give numerical integration results for Feynman loop diagrams through 3-loop such as those covered by Laporta [1]. The methods are based on automatic adaptive integration, using iterated integration and extrapolation with programs from the QUADPACK package, or multivariate techniques from the ParInt package. The Dqags algorithm from QuadPack accommodates boundary singularities of fairly general types. PARINT is a package for multivariate integration layered over MPI (Message Passing Interface), which runs on clusters and incorporates advanced parallel/distributed techniques such as load balancing among processes that may be distributed over a network of nodes. Results are included for 3-loop self-energy diagrams without IR (infra-red) or UV (ultra-violet) singularities. A procedure based on iterated integration and extrapolation yields a novel method of numerical regularization for integrals with UV terms, and is applied to a set of 2-loop self-energy diagrams with UV singularities.

  4. Semi-Infinite Cohomology of Loop Spaces

    NASA Astrophysics Data System (ADS)

    Shutler, Paul Maurice Edmund

    Available from UMI in association with The British Library. Requires signed TDF. This thesis attempts to construct a de Rham model for the Floer homology of the space of free loops on a symplectic manifold. It derives its inspiration principally from the work of Witten on topological quantum field theories. Chapter 1 consist of a review of background material followed by a number of elementary results. It is seen how Floer homology should naturally be representable by a semi-infinite generalisation of the ordinary de Rham theory associated to a manifold. In Chapter 2 the main attempt at constructing such a semi-infinite theory is made by defining an exterior derivative. Two different kinds of divergences are encountered and resolved. A suitable space of semi-infinite forms is constructed and some remarks are made about the likelihood that this model captures the Floer homology. In Chapter 3 the obstruction to the existence of a chiral factorisation of the bundle of fermionic Fock spaces over the loop space of the two-sphere is computed. For this purpose the ordinary cohomology ring of the loop space is calculated, also the action of the deck transformation on the cohomology of the simply connected covering space. In Chapter 4 the supersymmetric path integral approach to quantising topological field theories is developed formally. The semi-infinite dimensionality of the differential forms involved emerges naturally. The Floer homology of loop space is shown to be a ring. Its structure is calculated for the simple case of complex projective space. Chapter 5 concludes the thesis with some remarks about the action of the super-Virasoro algebra on the space of ordinary and semi-infinite differential forms respectively. Two short appendices are included describing a polynomial generating function for spherical harmonics and the spectrum of curl on vector fields on the three -sphere.

  5. A quadratic weight selection algorithm. [for optimal flight control

    NASA Technical Reports Server (NTRS)

    Broussard, J. R.

    1981-01-01

    A new numerical algorithm is presented which determines a positive semi-definite state weighting matrix in the linear-quadratic optimal control design problem. The algorithm chooses the weighting matrix by placing closed-loop eigenvalues and eigenvectors near desired locations using optimal feedback gains. A simplified flight control design example is used to illustrate the algorithms capabilities.

  6. Dual Brushless Resolver Rate Sensor

    NASA Technical Reports Server (NTRS)

    Howard, David E. (Inventor)

    1997-01-01

    A resolver rate sensor is disclosed in which dual brushless resolvers are mechanically coupled to the same output shaft. Diverse inputs are provided to each resolver by providing the first resolver with a DC input and the second resolver with an AC sinusoidal input. A trigonometric identity in which the sum of the squares of the sin and cosine components equal one is used to advantage in providing a sensor of increased accuracy. The first resolver may have a fixed or variable DC input to permit dynamic adjustment of resolver sensitivity thus permitting a wide range of coverage. In one embodiment of the invention the outputs of the first resolver are directly inputted into two separate multipliers and the outputs of the second resolver are inputted into the two separate multipliers, after being demodulated in a pair of demodulator circuits. The multiplied signals are then added in an adder circuit to provide a directional sensitive output. In another embodiment the outputs from the first resolver is modulated in separate modulator circuits and the output from the modulator circuits are used to excite the second resolver. The outputs from the second resolver are demodulated in separate demodulator circuit and added in an adder circuit to provide a direction sensitive rate output.

  7. CAVITY CONTROL ALGORITHM

    SciTech Connect

    Tomasz Plawski, J. Hovater

    2010-09-01

    A digital low level radio frequency (RF) system typically incorporates either a heterodyne or direct sampling technique, followed by fast ADCs, then an FPGA, and finally a transmitting DAC. This universal platform opens up the possibilities for a variety of control algorithm implementations. The foremost concern for an RF control system is cavity field stability, and to meet the required quality of regulation, the chosen control system needs to have sufficient feedback gain. In this paper we will investigate the effectiveness of the regulation for three basic control system algorithms: I&Q (In-phase and Quadrature), Amplitude & Phase and digital SEL (Self Exciting Loop) along with the example of the Jefferson Lab 12 GeV cavity field control system.

  8. HEATING OF FLARE LOOPS WITH OBSERVATIONALLY CONSTRAINED HEATING FUNCTIONS

    SciTech Connect

    Qiu Jiong; Liu Wenjuan; Longcope, Dana W.

    2012-06-20

    We analyze high-cadence high-resolution observations of a C3.2 flare obtained by AIA/SDO on 2010 August 1. The flare is a long-duration event with soft X-ray and EUV radiation lasting for over 4 hr. Analysis suggests that magnetic reconnection and formation of new loops continue for more than 2 hr. Furthermore, the UV 1600 Angstrom-Sign observations show that each of the individual pixels at the feet of flare loops is brightened instantaneously with a timescale of a few minutes, and decays over a much longer timescale of more than 30 minutes. We use these spatially resolved UV light curves during the rise phase to construct empirical heating functions for individual flare loops, and model heating of coronal plasmas in these loops. The total coronal radiation of these flare loops are compared with soft X-ray and EUV radiation fluxes measured by GOES and AIA. This study presents a method to observationally infer heating functions in numerous flare loops that are formed and heated sequentially by reconnection throughout the flare, and provides a very useful constraint to coronal heating models.

  9. Cloud Resolving Modeling

    NASA Technical Reports Server (NTRS)

    Tao, Wei-Kuo

    2007-01-01

    One of the most promising methods to test the representation of cloud processes used in climate models is to use observations together with cloud-resolving models (CRMs). CRMs use more sophisticated and realistic representations of cloud microphysical processes, and they can reasonably well resolve the time evolution, structure, and life cycles of clouds and cloud systems (with sizes ranging from about 2-200 km). CRMs also allow for explicit interaction between clouds, outgoing longwave (cooling) and incoming solar (heating) radiation, and ocean and land surface processes. Observations are required to initialize CRMs and to validate their results. This paper provides a brief discussion and review of the main characteristics of CRMs as well as some of their major applications. These include the use of CRMs to improve our understanding of: (1) convective organization, (2) cloud temperature and water vapor budgets, and convective momentum transport, (3) diurnal variation of precipitation processes, (4) radiative-convective quasi-equilibrium states, (5) cloud-chemistry interaction, (6) aerosol-precipitation interaction, and (7) improving moist processes in large-scale models. In addition, current and future developments and applications of CRMs will be presented.

  10. RESOLVE 2010 Field Test

    NASA Technical Reports Server (NTRS)

    Captain, J.; Quinn, J.; Moss, T.; Weis, K.

    2010-01-01

    This slide presentation reviews the field tests conducted in 2010 of the Regolith Environment Science & Oxygen & Lunar Volatile Extraction (RESOLVE). The Resolve program consist of several mechanism: (1) Excavation and Bulk Regolith Characterization (EBRC) which is designed to act as a drill and crusher, (2) Regolith Volatiles Characterization (RVC) which is a reactor and does gas analysis,(3) Lunar Water Resources Demonstration (LWRD) which is a fluid system, water and hydrogen capture device and (4) the Rover. The scientific goal of this test is to demonstrate evolution of low levels of hydrogen and water as a function of temperature. The Engineering goals of this test are to demonstrate:(1) Integration onto new rover (2) Miniaturization of electronics rack (3) Operation from battery packs (elimination of generator) (4) Remote command/control and (5) Operation while roving. Views of the 2008 and the 2010 mechanisms, a overhead view of the mission path, a view of the terrain, the two drill sites, and a graphic of the Master Events Controller Graphical User Interface (MEC GUI) are shown. There are descriptions of the Gas chromatography (GC), the operational procedure, water and hydrogen doping of tephra. There is also a review of some of the results, and future direction for research and tests.

  11. Resolving thermoelectric “paradox” in superconductors

    PubMed Central

    Shelly, Connor D.; Matrozova, Ekaterina A.; Petrashov, Victor T.

    2016-01-01

    For almost a century, thermoelectricity in superconductors has been one of the most intriguing topics in physics. During its early stages in the 1920s, the mere existence of thermoelectric effects in superconductors was questioned. In 1944, it was demonstrated that the effects may occur in inhomogeneous superconductors. Theoretical breakthrough followed in the 1970s, when the generation of a measurable thermoelectric magnetic flux in superconducting loops was predicted; however, a major crisis developed when experiments showed puzzling discrepancies with the theory. Moreover, different experiments were inconsistent with each other. This led to a stalemate in bringing theory and experiment into agreement. With this work, we resolve this stalemate, thus solving this long-standing “paradox,” and open prospects for exploration of novel thermoelectric phenomena predicted recently. PMID:26933688

  12. Coupled dual loop absorption heat pump

    DOEpatents

    Sarkisian, Paul H.; Reimann, Robert C.; Biermann, Wendell J.

    1985-01-01

    A coupled dual loop absorption system which utilizes two separate complete loops. Each individual loop operates at three temperatures and two pressures. This low temperature loop absorber and condenser are thermally coupled to the high temperature loop evaporator, and the high temperature loop condenser and absorber are thermally coupled to the low temperature generator.

  13. Loop quantum cosmology of Bianchi type IX models

    SciTech Connect

    Wilson-Ewing, Edward

    2010-08-15

    The loop quantum cosmology 'improved dynamics' of the Bianchi type IX model are studied. The action of the Hamiltonian constraint operator is obtained via techniques developed for the Bianchi type I and type II models, no new input is required. It is shown that the big bang and big crunch singularities are resolved by quantum gravity effects. We also present effective equations which provide quantum geometry corrections to the classical equations of motion.

  14. What's in the loop? The anatomy of double Higgs production

    NASA Astrophysics Data System (ADS)

    Dawson, S.; Ismail, A.; Low, Ian

    2015-06-01

    Determination of Higgs self-interactions through the double Higgs production from gluon fusion is a major goal of current and future collider experiments. We point out this channel could help disentangle and resolve the nature of ultraviolet contributions to Higgs couplings to two gluons. Analytic properties of the double Higgs amplitudes near kinematic threshold are used to study features resulting from scalar and fermionic loop particles mediating the interaction. Focusing on the h h invariant mass spectrum, we consider the effect from anomalous top and bottom Yukawa couplings, as well as from scalar and fermionic loop particles. In particular, the spectrum at high h h invariant mass is sensitive to the spin of the particles in the loop.

  15. Accelerating the loop expansion

    SciTech Connect

    Ingermanson, R.

    1986-07-29

    This thesis introduces a new non-perturbative technique into quantum field theory. To illustrate the method, I analyze the much-studied phi/sup 4/ theory in two dimensions. As a prelude, I first show that the Hartree approximation is easy to obtain from the calculation of the one-loop effective potential by a simple modification of the propagator that does not affect the perturbative renormalization procedure. A further modification then susggests itself, which has the same nice property, and which automatically yields a convex effective potential. I then show that both of these modifications extend naturally to higher orders in the derivative expansion of the effective action and to higher orders in the loop-expansion. The net effect is to re-sum the perturbation series for the effective action as a systematic ''accelerated'' non-perturbative expansion. Each term in the accelerated expansion corresponds to an infinite number of terms in the original series. Each term can be computed explicitly, albeit numerically. Many numerical graphs of the various approximations to the first two terms in the derivative expansion are given. I discuss the reliability of the results and the problem of spontaneous symmetry-breaking, as well as some potential applications to more interesting field theories. 40 refs.

  16. Georges Bank conflict resolved

    NASA Astrophysics Data System (ADS)

    Robb, David W.

    1984-04-01

    The International Court of Justice has resolved the long-term conflict between the United States and Canada over claims to mineral and living resources lying along the countries' common Atlantic maritime border. On October 12, in a 4-1 decision, the World Court rejected the United States' claim to the entire Georges Bank area, a region of the Continental Shelf off Massachusetts and Nova Scotia that is a prime fishing ground and is believed to have good potential for oil and gas deposits as well. The disputed area is roughly the top third of the Georges Bank area. The court awarded each country approximately half of this disputed area. No appeals are allowed under this decision.

  17. Reduction of One-Loop Amplitudes at the Integrand Level -- NLO QCD Calculations

    NASA Astrophysics Data System (ADS)

    Ossola, G.; Papadopoulos, C. G.; Pittau, R.

    2008-07-01

    The recently proposed method (OPP) to extract the coefficients of the scalar one-loop integrals to any multi-particle (sub)-amplitude is described. Within this method no analytical information on the structure of the amplitude is needed, allowing for a purely numerical, but still algebraic, implementation of the algorithm. The algorithm can be used to automatically perform one-loop calculation both in QCD and in the EW Theory. As an application, we give QCD one-loop results for the process p p to ZZZ at the LHC.

  18. The double loop mattress suture

    PubMed Central

    Biddlestone, John; Samuel, Madan; Creagh, Terry; Ahmad, Tariq

    2014-01-01

    An interrupted stitch type with favorable tissue characteristics will reduce local wound complications. We describe a novel high-strength, low-tension repair for the interrupted closure of skin, cartilage, and muscle, the double loop mattress stitch, and compare it experimentally with other interrupted closure methods. The performance of the double loop mattress technique in porcine cartilage and skeletal muscle is compared with the simple, mattress, and loop mattress interrupted sutures in both a novel porcine loading chamber and mechanical model. Wound apposition is assessed by electron microscopy. The performance of the double loop mattress in vivo was confirmed using a series of 805 pediatric laparotomies/laparoscopies. The double loop mattress suture is 3.5 times stronger than the loop mattress in muscle and 1.6 times stronger in cartilage (p ≤ 0.001). Additionally, the double loop mattress reduces tissue tension by 66% compared with just 53% for the loop mattress (p ≤ 0.001). Wound gapping is equal, and wound eversion appears significantly improved (p ≤ 0.001) compared with the loop mattress in vitro. In vivo, the double loop mattress performs as well as the loop mattress and significantly better than the mattress stitch in assessments of wound eversion and dehiscence. There were no episodes of stitch extrusion in our series of patients. The mechanical advantage of its intrinsic pulley arrangement gives the double loop mattress its favorable properties. Wound dehiscence is reduced because this stitch type is stronger and exerts less tension on the tissue than the mattress stitch. We advocate the use of this novel stitch wherever a high-strength, low-tension repair is required. These properties will enhance wound repair, and its application will be useful to surgeons of all disciplines. PMID:24698436

  19. The Seasonality Of The Loop Current

    NASA Astrophysics Data System (ADS)

    Hall, Cody Alan

    A total of 20 Loop Current eddy separation event dates were derived from Seasat and ERS-1 satellite altimetry, Coastal Zone Color Scanner chlorophyll-a images, Advanced Very High Resolution Radiometer sea surface temperature images, Horizon Marine, Inc. EddyWatch(TM) reports, and Climatology and Simulation of Eddies Eddy Joint Industry Project Gulf Eddy Model analyses spanning mid-1978 - 1992. There were many inconsistencies between the new "pre-altimetry" reanalysis dates derived from mostly non-altimeter data and dates published in past literature based on earlier versions of the pre-altimetry record. The reanalysis dates were derived from a larger compilation of data types and, consequently, were not as affected by intermittent and seasonal data outages common with past records. Therefore, the reanalysis dates are likely more accurate. About 30 Loop Current eddy separation dates were derived from altimetry data spanning 1993 -- 2012. The pre-altimetry and altimetry reanalysis dates along with similar altimetry dates published in other literature exhibit statistically significant seasonality. Eddy separation events are more likely in the months March, August, and September, and less likely in December. Reanalysis event dates were objectively divided into "spring" and "fall" seasons using a k-means clustering algorithm. The estimated spring and fall season centers are March 2nd and August 23 rd, respectively, with seasonal boundaries on May 22nd and December 3rd. The altimetry data suggest that Loop Current intrusion/retreat is dominantly an annual process. Loop Current metrics such as maximum northern boundary latitude and area are relatively high from January through about July and low in September and October. February metrics are statistically different than metrics in either October or November or both. This annual process is primarily driven by and dynamically linked to geostrophic currents seaward of the Campeche Bank shelf break forced by Kelvin waves

  20. Improved Speech Coding Based on Open-Loop Parameter Estimation

    NASA Technical Reports Server (NTRS)

    Juang, Jer-Nan; Chen, Ya-Chin; Longman, Richard W.

    2000-01-01

    A nonlinear optimization algorithm for linear predictive speech coding was developed early that not only optimizes the linear model coefficients for the open loop predictor, but does the optimization including the effects of quantization of the transmitted residual. It also simultaneously optimizes the quantization levels used for each speech segment. In this paper, we present an improved method for initialization of this nonlinear algorithm, and demonstrate substantial improvements in performance. In addition, the new procedure produces monotonically improving speech quality with increasing numbers of bits used in the transmitted error residual. Examples of speech encoding and decoding are given for 8 speech segments and signal to noise levels as high as 47 dB are produced. As in typical linear predictive coding, the optimization is done on the open loop speech analysis model. Here we demonstrate that minimizing the error of the closed loop speech reconstruction, instead of the simpler open loop optimization, is likely to produce negligible improvement in speech quality. The examples suggest that the algorithm here is close to giving the best performance obtainable from a linear model, for the chosen order with the chosen number of bits for the codebook.

  1. Modeling of compact loop antennas

    SciTech Connect

    Baity, F.W.

    1987-01-01

    A general compact loop antenna model which treats all elements of the antenna as lossy transmission lines has been developed. In addition to capacitively-tuned resonant double loop (RDL) antennas the model treats stub-tuned resonant double loop antennas. Calculations using the model have been compared with measurements on full-scale mockups of resonant double loop antennas for ATF and TFTR in order to refine the transmission line parameters. Results from the model are presented for RDL antenna designs for ATF, TFTR, Tore Supra, and for the Compact Ignition Tokamak (CIT).

  2. Loop Heat Pipe Startup Behaviors

    NASA Technical Reports Server (NTRS)

    Ku, Jentung

    2016-01-01

    A loop heat pipe must start successfully before it can commence its service. The startup transient represents one of the most complex phenomena in the loop heat pipe operation. This paper discusses various aspects of loop heat pipe startup behaviors. Topics include the four startup scenarios, the initial fluid distribution between the evaporator and reservoir that determines the startup scenario, factors that affect the fluid distribution between the evaporator and reservoir, difficulties encountered during the low power startup, and methods to enhance the startup success. Also addressed are the pressure spike and pressure surge during the startup transient, and repeated cycles of loop startup and shutdown under certain conditions.

  3. Heating Profiles of Coronal Loops

    NASA Astrophysics Data System (ADS)

    Plowman, Joseph; Kankelborg, Charles C.; Martens, Petrus C.

    2016-05-01

    We analyze the temperature and density profiles of coronal loops, as a function of their length, using data from SDO/AIA and Hinode/EIS. The analysis considers the location of the heating along the loop's length, and we conduct a more throrough investigation of our previous preliminary result that heating is concentrated near the loop footpoints. The work now features a larger selection of coronal loops, compared to our previous presentations, and examines their scale-height temperatures to ascertain the extent to which they are hydrostatic.

  4. Modeling of compact loop antennas

    NASA Astrophysics Data System (ADS)

    Baity, F. W.

    A general compact loop antenna model which treats all elements of the antenna as lossy transmission lines has been developed. In addition to capacitively-tuned resonant double loop (RDL) antennas the model treats stub-tuned resonant double loop antennas. Calculations using the model have been compared with measurements on full-scale mockups of resonant double loop antennas for ATF and TFTR in order to refine the transmission line parameters. Results from the model are presented for RDL antenna designs for ATF, TFTR, Tore Supra, and for the Compact Ignition Tokamak (CIT).

  5. Unstable anisotropic loop quantum cosmology

    SciTech Connect

    Nelson, William; Sakellariadou, Mairi

    2009-09-15

    We study stability conditions of the full Hamiltonian constraint equation describing the quantum dynamics of the diagonal Bianchi I model in the context of loop quantum cosmology. Our analysis has shown robust evidence of an instability in the explicit implementation of the difference equation, implying important consequences for the correspondence between the full loop quantum gravity theory and loop quantum cosmology. As a result, one may question the choice of the quantization approach, the model of lattice refinement, and/or the role of the ambiguity parameters; all these should, in principle, be dictated by the full loop quantum gravity theory.

  6. Generalized effective description of loop quantum cosmology

    NASA Astrophysics Data System (ADS)

    Ashtekar, Abhay; Gupt, Brajesh

    2015-10-01

    The effective description of loop quantum cosmology (LQC) has proved to be a convenient platform to study phenomenological implications of the quantum bounce that resolves the classical big bang singularity. Originally, this description was derived using Gaussian quantum states with small dispersions. In this paper we present a generalization to incorporate states with large dispersions. Specifically, we derive the generalized effective Friedmann and Raychaudhuri equations and propose a generalized effective Hamiltonian which are being used in an ongoing study of the phenomenological consequences of a broad class of quantum geometries. We also discuss an interesting interplay between the physics of states with larger dispersions in standard LQC, and of sharply peaked states in (hypothetical) LQC theories with larger area gap.

  7. Covariant entropy bound and loop quantum cosmology

    SciTech Connect

    Ashtekar, Abhay; Wilson-Ewing, Edward

    2008-09-15

    We examine Bousso's covariant entropy bound conjecture in the context of radiation filled, spatially flat, Friedmann-Robertson-Walker models. The bound is violated near the big bang. However, the hope has been that quantum gravity effects would intervene and protect it. Loop quantum cosmology provides a near ideal setting for investigating this issue. For, on the one hand, quantum geometry effects resolve the singularity and, on the other hand, the wave function is sharply peaked at a quantum corrected but smooth geometry, which can supply the structure needed to test the bound. We find that the bound is respected. We suggest that the bound need not be an essential ingredient for a quantum gravity theory but may emerge from it under suitable circumstances.

  8. Negative Selection Algorithm for Aircraft Fault Detection

    NASA Technical Reports Server (NTRS)

    Dasgupta, D.; KrishnaKumar, K.; Wong, D.; Berry, M.

    2004-01-01

    We investigated a real-valued Negative Selection Algorithm (NSA) for fault detection in man-in-the-loop aircraft operation. The detection algorithm uses body-axes angular rate sensory data exhibiting the normal flight behavior patterns, to generate probabilistically a set of fault detectors that can detect any abnormalities (including faults and damages) in the behavior pattern of the aircraft flight. We performed experiments with datasets (collected under normal and various simulated failure conditions) using the NASA Ames man-in-the-loop high-fidelity C-17 flight simulator. The paper provides results of experiments with different datasets representing various failure conditions.

  9. Loop-the-Loop: Bringing Theory into Practice

    ERIC Educational Resources Information Center

    Suwonjandee, N.; Asavapibhop, B.

    2012-01-01

    During the Thai high-school physics teacher training programme, we used an aluminum loop-the-loop system built by the Institute for the Promotion of Teaching Science and Technology (IPST) to demonstrate a circular motion and investigate the concept of the conservation of mechanical energy. There were 27 high-school teachers from three provinces,…

  10. Vortex loops and Majoranas

    SciTech Connect

    Chesi, Stefano; Jaffe, Arthur; Loss, Daniel; Pedrocchi, Fabio L.

    2013-11-15

    We investigate the role that vortex loops play in characterizing eigenstates of interacting Majoranas. We give some general results and then focus on ladder Hamiltonian examples as a test of further ideas. Two methods yield exact results: (i) A mapping of certain spin Hamiltonians to quartic interactions of Majoranas shows that the spectra of these two examples coincide. (ii) In cases with reflection-symmetric Hamiltonians, we use reflection positivity for Majoranas to characterize vortices in the ground states. Two additional methods suggest wider applicability of these results: (iii) Numerical evidence suggests similar behavior for certain systems without reflection symmetry. (iv) A perturbative analysis also suggests similar behavior without the assumption of reflection symmetry.

  11. Dynamic PID loop control

    SciTech Connect

    Pei, L.; Klebaner, A.; Theilacker, J.; Soyars, W.; Martinez, A.; Bossert, R.; DeGraff, B.; Darve, C.; /Fermilab

    2011-06-01

    The Horizontal Test Stand (HTS) SRF Cavity and Cryomodule 1 (CM1) of eight 9-cell, 1.3GHz SRF cavities are operating at Fermilab. For the cryogenic control system, how to hold liquid level constant in the cryostat by regulation of its Joule-Thompson JT-valve is very important after cryostat cool down to 2.0 K. The 72-cell cryostat liquid level response generally takes a long time delay after regulating its JT-valve; therefore, typical PID control loop should result in some cryostat parameter oscillations. This paper presents a type of PID parameter self-optimal and Time-Delay control method used to reduce cryogenic system parameters oscillation.

  12. Fluctuations in closed-loop fluorescent particle tracking

    NASA Astrophysics Data System (ADS)

    Berglund, Andrew J.; McHale, Kevin; Mabuchi, Hideo

    2007-06-01

    We present a comprehensive theory of closed-loop particle tracking for calculating the statistics of a diffusing fluorescent particle’s motion relative to the tracking lock point. A detailed comparison is made between the theory and experimental results, with excellent quantitative agreement found in all cases. A generalization of the theory of (open-loop) fluorescence correlation spectroscopy is developed, and the relationship to previous results is discussed. Two applications of the statistical techniques are given: a method for determining a tracked particle’s localization and an algorithm for rapid particle classification based on real-time analysis of the tracking control signal.

  13. Uranyl Nitrate Flow Loop

    SciTech Connect

    Ladd-Lively, Jennifer L

    2008-10-01

    The objectives of the work discussed in this report were to: (1) develop a flow loop that would simulate the purified uranium-bearing aqueous stream exiting the solvent extraction process in a natural uranium conversion plant (NUCP); (2) develop a test plan that would simulate normal operation and disturbances that could be anticipated in an NUCP; (3) use the flow loop to test commercially available flowmeters for use as safeguards monitors; and (4) recommend a flowmeter for production-scale testing at an NUCP. There has been interest in safeguarding conversion plants because the intermediate products [uranium dioxide (UO{sub 2}), uranium tetrafluoride (UF{sub 4}), and uranium hexafluoride (UF{sub 6})] are all suitable uranium feedstocks for producing special nuclear materials. Furthermore, if safeguards are not applied virtually any nuclear weapons program can obtain these feedstocks without detection by the International Atomic Energy Agency (IAEA). Historically, IAEA had not implemented safeguards until the purified UF{sub 6} product was declared as feedstock for enrichment plants. H. A. Elayat et al. provide a basic definition of a safeguards system: 'The function of a safeguards system on a chemical conversion plant is in general terms to verify that no useful nuclear material is being diverted to use in a nuclear weapons program'. The IAEA now considers all highly purified uranium compounds as candidates for safeguarding. DOE is currently interested in 'developing instruments, tools, strategies, and methods that could be of use to the IAEA in the application of safeguards' for materials found in the front end of the nuclear fuel cycle-prior to the production of the uranium hexafluoride or oxides that have been the traditional starting point for IAEA safeguards. Several national laboratories, including Oak Ridge, Los Alamos, Lawrence Livermore, and Brookhaven, have been involved in developing tools or techniques for safeguarding conversion plants. This study

  14. Loop-the-Loop: An Easy Experiment, A Challenging Explanation

    NASA Astrophysics Data System (ADS)

    Asavapibhop, B.; Suwonjandee, N.

    2010-07-01

    A loop-the-loop built by the Institute for the Promotion of Teaching Science and Technology (IPST) was used in Thai high school teachers training program to demonstrate a circular motion and investigate the concept of the conservation of mechanical energy. We took videos using high speed camera to record the motions of a spherical steel ball moving down the aluminum inclined track at different released positions. The ball then moved into the circular loop and underwent a projectile motion upon leaving the track. We then asked the teachers to predict the landing position of the ball if we changed the height of the whole loop-the-loop system. We also analyzed the videos using Tracker, a video analysis software. It turned out that most teachers did not realize the effect of the friction between the ball and the track and could not obtain the correct relationship hence their predictions were inconsistent with the actual landing positions of the ball.

  15. Dual Brushless Resolver Rate Sensor

    NASA Technical Reports Server (NTRS)

    Howard, David E. (Inventor)

    1996-01-01

    This invention relates to dual analog angular rate sensors which are implemented without the use of mechanical brushes. A resolver rate sensor which includes two brushless resolvers which are mechanically coupled to the same output shaft is provided with inputs which are provided to each resolver by providing the first resolver with a DC input and the second resolver with an AC sinusoidal input. A trigonometric identity in which the sum of the squares of the sin and cosine components equal one is used to advantage in providing a sensor of increased accuracy. The first resolver may have a fixed or variable DC input to permit dynamic adjustment of resolver sensitivity thus permitting a wide range of coverage. Novelty and advantages of the invention reside in the excitation of a resolver with a DC signal and in the utilization of two resolvers and the trigonometric identity of cos(exp 2)(theta) + sin(exp 2)(theta) = 1 to provide an accurate rate sensor which is sensitive to direction and accurate through zero rate.

  16. Research on Signal Processing Algorithms in GPS Receivers

    NASA Astrophysics Data System (ADS)

    Cai, Fan; Yin, Yan; Zhang, Xiu-Zhong

    2007-03-01

    The modern standard satellite navigation receivers are commonly based on ASICs for signal processing and fast microprocessors for application calculations. The software satellite navigation receiver is also developed in recent years. The research on software receivers becomes one trend of satellite navigation receiver. For algorithms on signal processing play an important role in satellite navigation receivers, the paper illuminates the signal processing algorithms in detail. The GPS receiver is widely used at present. So the paper places emphasis on signal processing algorithms about GPS receiver. Signal processing algorithms include three aspects: the algorithm on signal acquisition, the algorithm on carrier tracking and the algorithm on PRN (pseudo random noise) code tracking. In the part of signal acquisition, the method of using FFT to get the result of circular correlation is introduced. The paper carefully researches the method and discusses the derivation process of the method. In the part of carrier tracking, the paper describes the principle of frequency locked loop (FLL) and phase locked loop (PLL) and analyzes the principle of loop filter. The method of transition from s-domain to z-domain is introduced. The computation of noise bandwidth of the loop filter are expatiated and the structures of one-step digital loop filter, two-step digital loop filter and three step are given. Other parameters of loop filters are also given. In the part of code tracking, delay-early locked loop (DLL) is introduced. Theoretical analysis and experiment results demonstrate the algorithms in the paper. Through the simulation testing, the performance of combination of PLL and FLL can be acknowledged.

  17. Causal Loop Analysis of coastal geomorphological systems

    NASA Astrophysics Data System (ADS)

    Payo, Andres; Hall, Jim W.; French, Jon; Sutherland, James; van Maanen, Barend; Nicholls, Robert J.; Reeve, Dominic E.

    2016-03-01

    As geomorphologists embrace ever more sophisticated theoretical frameworks that shift from simple notions of evolution towards single steady equilibria to recognise the possibility of multiple response pathways and outcomes, morphodynamic modellers are facing the problem of how to keep track of an ever-greater number of system feedbacks. Within coastal geomorphology, capturing these feedbacks is critically important, especially as the focus of activity shifts from reductionist models founded on sediment transport fundamentals to more synthesist ones intended to resolve emergent behaviours at decadal to centennial scales. This paper addresses the challenge of mapping the feedback structure of processes controlling geomorphic system behaviour with reference to illustrative applications of Causal Loop Analysis at two study cases: (1) the erosion-accretion behaviour of graded (mixed) sediment beds, and (2) the local alongshore sediment fluxes of sand-rich shorelines. These case study examples are chosen on account of their central role in the quantitative modelling of geomorphological futures and as they illustrate different types of causation. Causal loop diagrams, a form of directed graph, are used to distil the feedback structure to reveal, in advance of more quantitative modelling, multi-response pathways and multiple outcomes. In the case of graded sediment bed, up to three different outcomes (no response, and two disequilibrium states) can be derived from a simple qualitative stability analysis. For the sand-rich local shoreline behaviour case, two fundamentally different responses of the shoreline (diffusive and anti-diffusive), triggered by small changes of the shoreline cross-shore position, can be inferred purely through analysis of the causal pathways. Explicit depiction of feedback-structure diagrams is beneficial when developing numerical models to explore coastal morphological futures. By explicitly mapping the feedbacks included and neglected within a

  18. Neurochemostat: A Neural Interface SoC With Integrated Chemometrics for Closed-Loop Regulation of Brain Dopamine.

    PubMed

    Bozorgzadeh, Bardia; Schuweiler, Douglas R; Bobak, Martin J; Garris, Paul A; Mohseni, Pedram

    2016-06-01

    This paper presents a 3.3×3.2 mm(2) system-on-chip (SoC) fabricated in AMS 0.35 μm 2P/4M CMOS for closed-loop regulation of brain dopamine. The SoC uniquely integrates neurochemical sensing, on-the-fly chemometrics, and feedback-controlled electrical stimulation to realize a "neurochemostat" by maintaining brain levels of electrically evoked dopamine between two user-set thresholds. The SoC incorporates a 90 μW, custom-designed, digital signal processing (DSP) unit for real-time processing of neurochemical data obtained by 400 V/s fast-scan cyclic voltammetry (FSCV) with a carbon-fiber microelectrode (CFM). Specifically, the DSP unit executes a chemometrics algorithm based upon principal component regression (PCR) to resolve in real time electrically evoked brain dopamine levels from pH change and CFM background-current drift, two common interferents encountered using FSCV with a CFM in vivo. Further, the DSP unit directly links the chemically resolved dopamine levels to the activation of the electrical microstimulator in on-off-keying (OOK) fashion. Measured results from benchtop testing, flow injection analysis (FIA), and biological experiments with an anesthetized rat are presented. PMID:26390501

  19. Modeling of hysteresis loops by Monte Carlo simulation

    NASA Astrophysics Data System (ADS)

    Nehme, Z.; Labaye, Y.; Sayed Hassan, R.; Yaacoub, N.; Greneche, J. M.

    2015-12-01

    Recent advances in MC simulations of magnetic properties are rather devoted to non-interacting systems or ultrafast phenomena, while the modeling of quasi-static hysteresis loops of an assembly of spins with strong internal exchange interactions remains limited to specific cases. In the case of any assembly of magnetic moments, we propose MC simulations on the basis of a three dimensional classical Heisenberg model applied to an isolated magnetic slab involving first nearest neighbors exchange interactions and uniaxial anisotropy. Three different algorithms were successively implemented in order to simulate hysteresis loops: the classical free algorithm, the cone algorithm and a mixed one consisting of adding some global rotations. We focus particularly our study on the impact of varying the anisotropic constant parameter on the coercive field for different temperatures and algorithms. A study of the angular acceptation move distribution allows the dynamics of our simulations to be characterized. The results reveal that the coercive field is linearly related to the anisotropy providing that the algorithm and the numeric conditions are carefully chosen. In a general tendency, it is found that the efficiency of the simulation can be greatly enhanced by using the mixed algorithm that mimic the physics of collective behavior. Consequently, this study lead as to better quantified coercive fields measurements resulting from physical phenomena of complex magnetic (nano)architectures with different anisotropy contributions.

  20. Mechanism of promoter repression by Lac repressor-DNA loops.

    PubMed

    Becker, Nicole A; Peters, Justin P; Maher, L James; Lionberger, Troy A

    2013-01-01

    The Escherichia coli lactose (lac) operon encodes the first genetic switch to be discovered, and lac remains a paradigm for studying negative and positive control of gene expression. Negative control is believed to involve competition of RNA polymerase and Lac repressor for overlapping binding sites. Contributions to the local Lac repressor concentration come from free repressor and repressor delivered to the operator from remote auxiliary operators by DNA looping. Long-standing questions persist concerning the actual role of DNA looping in the mechanism of promoter repression. Here, we use experiments in living bacteria to resolve four of these questions. We show that the distance dependence of repression enhancement is comparable for upstream and downstream auxiliary operators, confirming the hypothesis that repressor concentration increase is the principal mechanism of repression loops. We find that as few as four turns of DNA can be constrained in a stable loop by Lac repressor. We show that RNA polymerase is not trapped at repressed promoters. Finally, we show that constraining a promoter in a tight DNA loop is sufficient for repression even when promoter and operator do not overlap. PMID:23143103

  1. Temperature and Density Analysis of a Coronal Loop Using EIS

    NASA Astrophysics Data System (ADS)

    Garst, J. W.; Schmelz, J. T.

    2008-05-01

    The temperature analysis of coronal loops has produced contradictory results. Image ratios from TRACE show substantially smaller temperature gradients than predicted by standard models for loops in hydrodynamic equilibrium. TRACE has state-of-the-art spatial resolution but limited temperature coverage. On the other hand, the pixels of the Coronal Diagnostics Spectrometer (CDS) on SOHO are larger but its temperature resolution is state-of-the-art. Loop results from differential emission measure analyses from CDS data have been questioned due to the resolving power. Loop analysis could benefit greatly from observations by an instrument with the spatial resolution of TRACE and the temperature coverage of CDS. A spectrometer with (almost) these characteristics was launched in September 2006 on the Japanese/USA/UK Hinode mission. The EUV Imaging Spectrometer (EIS) is similar to CDS, observing emission lines originating from the solar corona and upper transition region at wavelength intervals in the extreme ultraviolet, but with a spatial resolution that is almost as good as TRACE. Differential emission measure and density analysis is done on the coronal loop data observed by EIS on 01 June 2007. Results from CDS and TRACE analysis are compared and discussed qualitatively. Solar physics research at the University of Memphis is supported by a Hinode subcontract from NASA/SAO as well as NSF ATM-0402729.

  2. Loop quantum cosmology of Bianchi type I models

    SciTech Connect

    Ashtekar, Abhay; Wilson-Ewing, Edward

    2009-04-15

    The ''improved dynamics'' of loop quantum cosmology is extended to include anisotropies of the Bianchi type I model. As in the isotropic case, a massless scalar field serves as a relational time parameter. However, the extension is nontrivial because one has to face several conceptual subtleties as well as technical difficulties. These include a better understanding of the relation between loop quantum gravity and loop quantum cosmology, handling novel features associated with the nonlocal field strength operator in presence of anisotropies, and finding dynamical variables that make the action of the Hamiltonian constraint manageable. Our analysis provides a conceptually complete description that overcomes limitations of earlier works. We again find that the big-bang singularity is resolved by quantum geometry effects but, because of the presence of Weyl curvature, Planck scale physics is now much richer than in the isotropic case. Since the Bianchi I models play a key role in the Belinskii, Khalatnikov, Lifshitz conjecture on the nature of generic spacelike singularities in general relativity, the quantum dynamics of Bianchi I cosmologies is likely to provide considerable intuition about the fate of generic spacelike singularities in quantum gravity. Finally, we show that the quantum dynamics of Bianchi I cosmologies projects down exactly to that of the Friedmann model. This opens a new avenue to relate more complicated models to simpler ones, thereby providing a new tool to relate the quantum dynamics of loop quantum gravity to that of loop quantum cosmology.

  3. Loop quantum cosmology of Bianchi type I models

    NASA Astrophysics Data System (ADS)

    Ashtekar, Abhay; Wilson-Ewing, Edward

    2009-04-01

    The “improved dynamics” of loop quantum cosmology is extended to include anisotropies of the Bianchi type I model. As in the isotropic case, a massless scalar field serves as a relational time parameter. However, the extension is nontrivial because one has to face several conceptual subtleties as well as technical difficulties. These include a better understanding of the relation between loop quantum gravity and loop quantum cosmology, handling novel features associated with the nonlocal field strength operator in presence of anisotropies, and finding dynamical variables that make the action of the Hamiltonian constraint manageable. Our analysis provides a conceptually complete description that overcomes limitations of earlier works. We again find that the big-bang singularity is resolved by quantum geometry effects but, because of the presence of Weyl curvature, Planck scale physics is now much richer than in the isotropic case. Since the Bianchi I models play a key role in the Belinskii, Khalatnikov, Lifshitz conjecture on the nature of generic spacelike singularities in general relativity, the quantum dynamics of Bianchi I cosmologies is likely to provide considerable intuition about the fate of generic spacelike singularities in quantum gravity. Finally, we show that the quantum dynamics of Bianchi I cosmologies projects down exactly to that of the Friedmann model. This opens a new avenue to relate more complicated models to simpler ones, thereby providing a new tool to relate the quantum dynamics of loop quantum gravity to that of loop quantum cosmology.

  4. Inverse problem for the current loop model: Possibilities and restrictions

    NASA Astrophysics Data System (ADS)

    Demina, I. M.; Farafonova, Yu. G.

    2016-07-01

    The possibilities of determining arbitrary current loop parameters based on the spatial structures of the magnetic field components generated by this loop on a sphere with a specified radius have been considered with the use of models. The model parameters were selected such that anomalies created by current loops on a sphere with a radius of 6378 km would be comparable in value with the different-scale anomalies of the observed main geomagnetic field (MGF). The least squares method was used to solve the inverse problem. Estimates close to the specified values were obtained for all current loop parameters except the current strength and radius. The radius determination error can reach ±120 km; at the same time, the magnetic moment value is determined with an accuracy of ±1%. The resolvability of the current force and radius can to a certain degree be improved by decreasing the observation sphere radius such that the ratio of the source distance to the current loop radius would be at least smaller than eight, which can be difficult to reach when modeling MGF.

  5. Standing Kink modes in three-dimensional coronal loops

    SciTech Connect

    Pascoe, D. J.; De Moortel, I.

    2014-04-01

    So far, the straight flux tube model proposed by Edwin and Roberts is the most commonly used tool in practical coronal seismology, in particular, to infer values of the (coronal) magnetic field from observed, standing kink mode oscillations. In this paper, we compare the period predicted by this basic model with three-dimensional (3D) numerical simulations of standing kink mode oscillations, as the period is a crucial parameter in the seismological inversion to determine the magnetic field. We perform numerical simulations of standing kink modes in both straight and curved 3D coronal loops and consider excitation by internal and external drivers. The period of oscillation for the displacement of dense coronal loops is determined by the loop length and the kink speed, in agreement with the estimate based on analytical theory for straight flux tubes. For curved coronal loops embedded in a magnetic arcade and excited by an external driver, a secondary mode with a period determined by the loop length and external Alfvén speed is also present. When a low number of oscillations is considered, these two periods can result in a single, non-resolved (broad) peak in the power spectrum, particularly for low values of the density contrast for which the two periods will be relatively similar. In that case (and for this particular geometry), the presence of this additional mode would lead to ambiguous seismological estimates of the magnetic field strength.

  6. Wilson Loop Diagrams and Positroids

    NASA Astrophysics Data System (ADS)

    Agarwala, Susama; Marin-Amat, Eloi

    2016-07-01

    In this paper, we study a new application of the positive Grassmannian to Wilson loop diagrams (or MHV diagrams) for scattering amplitudes in N= 4 Super Yang-Mill theory (N = 4 SYM). There has been much interest in studying this theory via the positive Grassmannians using BCFW recursion. This is the first attempt to study MHV diagrams for planar Wilson loop calculations (or planar amplitudes) in terms of positive Grassmannians. We codify Wilson loop diagrams completely in terms of matroids. This allows us to apply the combinatorial tools in matroid theory used to identify positroids (non-negative Grassmannians) to Wilson loop diagrams. In doing so, we find that certain non-planar Wilson loop diagrams define positive Grassmannians. While non-planar diagrams do not have physical meaning, this finding suggests that they may have value as an algebraic tool, and deserve further investigation.

  7. Loop-bed combustion apparatus

    DOEpatents

    Shang, Jer-Yu; Mei, Joseph S.; Slagle, Frank D.; Notestein, John E.

    1984-01-01

    The present invention is directed to a combustion apparatus in the configuration of a oblong annulus defining a closed loop. Particulate coal together with a sulfur sorbent such as sulfur or dolomite is introduced into the closed loop, ignited, and propelled at a high rate of speed around the loop. Flue gas is withdrawn from a location in the closed loop in close proximity to an area in the loop where centrifugal force imposed upon the larger particulate material maintains these particulates at a location spaced from the flue gas outlet. Only flue gas and smaller particulates resulting from the combustion and innerparticle grinding are discharged from the combustor. This structural arrangement provides increased combustion efficiency due to the essentially complete combustion of the coal particulates as well as increased sulfur absorption due to the innerparticle grinding of the sorbent which provides greater particle surface area.

  8. Loop Heat Pipe Startup Behaviors

    NASA Technical Reports Server (NTRS)

    Ku, Jentung

    2014-01-01

    A loop heat pipe must start successfully before it can commence its service. The start-up transient represents one of the most complex phenomena in the loop heat pipe operation. This paper discusses various aspects of loop heat pipe start-up behaviors. Topics include the four start-up scenarios, the initial fluid distribution between the evaporator and reservoir that determines the start-up scenario, factors that affect the fluid distribution between the evaporator and reservoir, difficulties encountered during the low power start-up, and methods to enhance the start-up success. Also addressed are the thermodynamic constraint between the evaporator and reservoir in the loop heat pipe operation, the superheat requirement for nucleate boiling, pressure spike and pressure surge during the start-up transient, and repeated cycles of loop start-up andshutdown under certain conditions.

  9. Circumstellar shells resolved in the IRAS survey data. I - Data processing procedure, results, and confidence tests

    NASA Technical Reports Server (NTRS)

    Young, K.; Phillips, T. G.; Knapp, G. R.

    1993-01-01

    We have examined the IRAS 60 and 100 micron survey data covering 512 evolved stars and young planetary nebulae for evidence of spatially resolved structure. A simple model, consisting of a central unresolved source surrounded by a resolved isothermal shell, was fitted to the data for each star. Seventy-six stars were found to be resolved in the 60 micron data. Tests have been performed to verify that the extended structure seen is not an artifact of the data-processing algorithm.

  10. Cloud-Resolving Model and GPM

    NASA Technical Reports Server (NTRS)

    Tao, Wei-Kuo; Lang, S.; Simpson, J.; Adler, R.; Hou, A.; Li, X.; Shie, C.-L.; Olson, W.; Kummerow, C.

    2003-01-01

    Over the past twenty years, rainfall retrieval algorithms have been developed to retrieve rainfall and vertical hydrometeor structures from passive microwave observations by making use of the fact that weighting functions for various frequencies peak at different levels within a rainy atmosphere. GPROF is one of two TMI rainfall algorithms. It is physically based retrieval that finds the vertical hydrometeor profile that best fits the brightness temperatures in the available passive radiometer channels. Matching is achieved using a library of hydrometeor profiles generated by cloud-resolving models (CRMs). The hydrometeor profiles have a corresponding surface precipitation rate. The algorithm retrieves the hydrometeor profiles and associated surface rainfall using a Bayesian approach that gives the estimated expected values. The ability of CRMs to produce cloud structures that are reliable and representative of observed storms is crucial for the success of GPROF. The cloud mycrophysics are one of the keys to achieving this. In addition, CRMs have been a very useful tool for GPM-algorithm developers through Cloud-Radiation Simulations (CRS), one of the nine GPM disciplinary research themes. This paper will discuss how to generate consistent and comprehensive 4D cloud datasets from an improved (i.e., in regard to bulk and multi-moment microphysics) CRM for TRMM and GPM rainfall retrieval algorithm developers. These cloud datasets include CRM-simulated clouds and cloud systems from different geographic locations in the tropics and midlatitudes. By linking the CRM with a passive microwave radiative-transfer model and using satellite and airborne data, the performance of the "cloud physics" can be assessed and in turn modified and improved. This paper will also address how to assess and improve the performance of various latent and diabatic heating algorithms and develop an algorithm to retrieve the vertical structure of apparent moistening (Q2). Considering that the

  11. Quantum algorithms

    NASA Astrophysics Data System (ADS)

    Abrams, Daniel S.

    This thesis describes several new quantum algorithms. These include a polynomial time algorithm that uses a quantum fast Fourier transform to find eigenvalues and eigenvectors of a Hamiltonian operator, and that can be applied in cases (commonly found in ab initio physics and chemistry problems) for which all known classical algorithms require exponential time. Fast algorithms for simulating many body Fermi systems are also provided in both first and second quantized descriptions. An efficient quantum algorithm for anti-symmetrization is given as well as a detailed discussion of a simulation of the Hubbard model. In addition, quantum algorithms that calculate numerical integrals and various characteristics of stochastic processes are described. Two techniques are given, both of which obtain an exponential speed increase in comparison to the fastest known classical deterministic algorithms and a quadratic speed increase in comparison to classical Monte Carlo (probabilistic) methods. I derive a simpler and slightly faster version of Grover's mean algorithm, show how to apply quantum counting to the problem, develop some variations of these algorithms, and show how both (apparently distinct) approaches can be understood from the same unified framework. Finally, the relationship between physics and computation is explored in some more depth, and it is shown that computational complexity theory depends very sensitively on physical laws. In particular, it is shown that nonlinear quantum mechanics allows for the polynomial time solution of NP-complete and #P oracle problems. Using the Weinberg model as a simple example, the explicit construction of the necessary gates is derived from the underlying physics. Nonlinear quantum algorithms are also presented using Polchinski type nonlinearities which do not allow for superluminal communication. (Copies available exclusively from MIT Libraries, Rm. 14- 0551, Cambridge, MA 02139-4307. Ph. 617-253-5668; Fax 617-253-1690.)

  12. Identification of system, observer, and controller from closed-loop experimental data

    NASA Technical Reports Server (NTRS)

    Juang, Jer-Nan; Phan, Minh

    1992-01-01

    This paper considers the identification problem of a system operating in closed-loop with an existing feedback controller. The closed-loop system is excited by a known excitation signal, and the resulting time histories of the closed-loop system response and the feedback signal are measured. From the time history data, the algorithm computes the Markov parameters of a closed-loop observer, from which the Markov parameters of the individual open-loop plant, observer, and controller are recovered. A state space model of the open-loop plant and the gain matrices for the controller and the observer are then realized. The results of the paper are demonstrated by an example using actual aircraft flutter test data.

  13. A study of digital gyro compensation loops. [data conversion routines and breadboard models

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The feasibility is discussed of replacing existing state-of-the-art analog gyro compensation loops with digital computations. This was accomplished by designing appropriate compensation loops for the dry turned TDF gyro, selecting appropriate data conversion and processing techniques and algorithms, and breadboarding the design for laboratory evaluation. A breadboard design was established in which one axis of a Teledyne turned-gimbal TDF gyro was caged digitally while the other was caged using conventional analog electronics. The digital loop was designed analytically to closely resemble the analog loop in performance. The breadboard was subjected to various static and dynamic tests in order to establish the relative stability characteristics and frequency responses of the digital and analog loops. Several variations of the digital loop configuration were evaluated. The results were favorable.

  14. Resolvent mode identification in a turbulent boundary layer

    NASA Astrophysics Data System (ADS)

    Rosenberg, Kevin; McKeon, Beverley

    2014-11-01

    The resolvent analysis developed by McKeon and Sharma (J. Fluid Mechanics, 2010) has demonstrated a connection between the most amplified disturbances in wavenumber/frequency space and observed structures in wall turbulence. Three simultaneous hotwire measurements are made across a zero-pressure gradient turbulent boundary layer to identify the resolvent modes associated with these structures. A resolvent mode is designated by a streamwise wavenumber, a spanwise number, and a temporal frequency (k, n, ω respectively) and physically represents a travelling wave. The three wires are aligned in the wall normal direction and spaced in the streamwise and spanwise directions. The signals are filtered at the frequency corresponding to the resolvent mode of interest and ensemble averaged over a single period; the resulting phase differences between wires and their respective separation distances allows for the calculation of the spatial wavenumbers. The eventual goal is to sense these modes in real time as this will provide an important first step towards the development of closed-loop control schemes, specifically within the context of the resolvent framework. The support of the Air Force Office of Scientific Research under Grant # FA 9550-12-1-0469 (P.M. Doug Smith) is gratefully acknowledged.

  15. Closed-loop real-time infrared scene generator

    NASA Astrophysics Data System (ADS)

    Crow, Dennis R.; Coker, Charles F.; Garbo, Dennis L.; Olson, Eric M.

    1998-07-01

    A computer program has been developed to provide closed-loop infrared imagery of composite targets and backgrounds in real- time. This program operates on parametric databases generated off-line by computationally intensive first principle physics codes such as the Composite Hardbody and Missile Plume (CHAMP) program, Synthetic Scene Generation Model (SSGM), and Multi- Spectral Modeling and Analysis (MSMA/Irma program. The parametric databases allow dynamic variations in flight and engagement scenarios to be modeled as closed-loop guidance and control algorithms modify the operational dynamics. The program is tightly coupled with the parametric databases to produce infrared radiation results in real-time and OpenGL graphic libraries to interface with high performance graphic hardware. The program is being sponsored for development by the Kinetic Kill Vehicle Hardware-in-the-Loop Simulator facility of the Air Force Research Laboratory Munitions Directorate located at Eglin AFB, Florida.

  16. VERSATILE TWO-AXIS OPEN-LOOP SOLAR TRACKER CONTROLLER*

    SciTech Connect

    Ward, Christina D; Maxey, L Curt; Evans III, Boyd Mccutchen; Lapsa, Melissa Voss

    2008-01-01

    A versatile single-board controller for two-axis solar tracking applications has been developed and tested on operating solar tracking systems with over two years of field experience. The operating experience gained from the two systems and associated modifications are discussed as representative examples of the practical issues associated with implementing a new two-axis solar tracker design. In this research, open and closed loop control methods were evaluated; however, only the open loop method met the 0.125 tracking accuracy requirement and the requirement to maintain pointing accuracy in hazy and scattered cloudy skies. The open loop algorithm was finally implemented in a microcontroller-based tracking system. Methods of applying this controller hardware to different tracker geometries and hardware are discussed along with the experience gained to date.

  17. Haplotyping algorithms

    SciTech Connect

    Sobel, E.; Lange, K.; O`Connell, J.R.

    1996-12-31

    Haplotyping is the logical process of inferring gene flow in a pedigree based on phenotyping results at a small number of genetic loci. This paper formalizes the haplotyping problem and suggests four algorithms for haplotype reconstruction. These algorithms range from exhaustive enumeration of all haplotype vectors to combinatorial optimization by simulated annealing. Application of the algorithms to published genetic analyses shows that manual haplotyping is often erroneous. Haplotyping is employed in screening pedigrees for phenotyping errors and in positional cloning of disease genes from conserved haplotypes in population isolates. 26 refs., 6 figs., 3 tabs.

  18. Digital phase-locked loop

    NASA Technical Reports Server (NTRS)

    Cliff, R. A. (Inventor)

    1975-01-01

    An digital phase-locked loop is provided for deriving a loop output signal from an accumulator output terminal. A phase detecting exclusive OR gate is fed by the loop digital input and output signals. The output of the phase detector is a bi-level digital signal having a duty cycle indicative of the relative phase of the input and output signals. The accumulator is incremented at a first rate in response to a first output level of the phase detector and at a second rate in response to a second output level of the phase detector.

  19. An Environment for Hardware-in-the-Loop Formation Navigation and Control Simulation

    NASA Technical Reports Server (NTRS)

    Burns, Rich

    2004-01-01

    Recent interest in formation flying satellite systems has spurred a considerable amount of research in the relative navigation and control of satellites. Development in this area has included new estimation and control algorithms as well as sensor and actuator development specifically geared toward the relative control problem. This paper describes a simulation facility, the Formation Flying Testbed (FFTB) at NASA's Goddard Space Flight Center, which allows engineers to test new algorithms for the formation flying problem with relevant GN&C hardware in a closed loop simulation. The FFTB currently supports the injection of GPS receiver hardware into the simulation loop, and support for satellite crosslink ranging technology is at a prototype stage. This closed-loop, hardware inclusive simulation capability permits testing of navigation and control software in the presence of the actual hardware with which the algorithms must interact. This capability provides the navigation or control developer with a perspective on how the algorithms perform as part of the closed-loop system. In this paper, the overall design and evolution of the FFTB are presented. Each component of the FFTB is then described in detail. Interfaces between the components of the FFTB are shown and the interfaces to and between navigation and control software are described in detail. Finally, an example of closed-loop formation control with GPS receivers in the loop is presented and results are analyzed.

  20. An Environmental for Hardware-in-the-Loop Formation Navigation and Control

    NASA Technical Reports Server (NTRS)

    Burns, Rich; Naasz, Bo; Gaylor, Dave; Higinbotham, John

    2004-01-01

    Recent interest in formation flying satellite systems has spurred a considerable amount of research in the relative navigation and control of satellites. Development in this area has included new estimation and control algorithms as well as sensor and actuator development specifically geared toward the relative control problem. This paper describes a simulation facility, the Formation Flying Test Bed (FFTB) at NASA Goddard Space Flight Center, which allows engineers to test new algorithms for the formation flying problem with relevant GN&C hardware in a closed loop simulation. The FFTB currently supports the inclusion of GPS receiver hardware in the simulation loop. Support for satellite crosslink ranging technology is at a prototype stage. This closed-loop, hardware inclusive simulation capability permits testing of navigation and control software in the presence of the actual hardware with which the algorithms must interact. This capability provides the navigation or control developer with a perspective on how the algorithms perform as part of the closed-loop system. In this paper, the overall design and evolution of the FFTB are presented. Each component of the FFTB is then described. Interfaces between the components of the FFTB are shown and the interfaces to and between navigation and control software are described. Finally, an example of closed-loop formation control with GPS receivers in the loop is presented.

  1. RESOLVE and ECO: Survey Design

    NASA Astrophysics Data System (ADS)

    Kannappan, Sheila; Moffett, Amanda J.; Norris, Mark A.; Eckert, Kathleen D.; Stark, David; Berlind, Andreas A.; Snyder, Elaine M.; Norman, Dara J.; Hoversten, Erik A.; RESOLVE Team

    2016-01-01

    The REsolved Spectroscopy Of a Local VolumE (RESOLVE) survey is a volume-limited census of stellar, gas, and dynamical mass as well as star formation and galaxy interactions within >50,000 cubic Mpc of the nearby cosmic web, reaching down to dwarf galaxies of baryonic mass ~10^9 Msun and spanning multiple large-scale filaments, walls, and voids. RESOLVE is surrounded by the ~10x larger Environmental COntext (ECO) catalog, with matched custom photometry and environment metrics enabling analysis of cosmic variance with greater statistical power. For the ~1500 galaxies in its two equatorial footprints, RESOLVE goes beyond ECO in providing (i) deep 21cm data with adaptive sensitivity ensuring HI mass detections or upper limits <10% of the stellar mass and (ii) 3D optical spectroscopy including both high-resolution ionized gas or stellar kinematic data for each galaxy and broad 320-725nm spectroscopy spanning [OII] 3727, Halpha, and Hbeta. RESOLVE is designed to complement other radio and optical surveys in providing diverse, contiguous, and uniform local/global environment data as well as unusually high completeness extending into the gas-dominated dwarf galaxy regime. RESOLVE also offers superb reprocessed photometry including full, deep NUV coverage and synergy with other equatorial surveys as well as unique northern and southern facilities such as Arecibo, the GBT, and ALMA. The RESOLVE and ECO surveys have been supported by funding from NSF grants AST-0955368 and OCI-1156614.

  2. Automated Coronal Loop Identification Using Digital Image Processing Techniques

    NASA Technical Reports Server (NTRS)

    Lee, Jong K.; Gary, G. Allen; Newman, Timothy S.

    2003-01-01

    The results of a master thesis project on a study of computer algorithms for automatic identification of optical-thin, 3-dimensional solar coronal loop centers from extreme ultraviolet and X-ray 2-dimensional images will be presented. These center splines are proxies of associated magnetic field lines. The project is pattern recognition problems in which there are no unique shapes or edges and in which photon and detector noise heavily influence the images. The study explores extraction techniques using: (1) linear feature recognition of local patterns (related to the inertia-tensor concept), (2) parametric space via the Hough transform, and (3) topological adaptive contours (snakes) that constrains curvature and continuity as possible candidates for digital loop detection schemes. We have developed synthesized images for the coronal loops to test the various loop identification algorithms. Since the topology of these solar features is dominated by the magnetic field structure, a first-order magnetic field approximation using multiple dipoles provides a priori information in the identification process. Results from both synthesized and solar images will be presented.

  3. The Future of Seizure Prediction and Intervention: Closing the loop

    PubMed Central

    Nagaraj, Vivek; Lee, Steven; Krook-Magnuson, Esther; Soltesz, Ivan; Benquet, Pascal; Irazoqui, Pedro; Netoff, Theoden

    2014-01-01

    The ultimate goal of epilepsy therapies is to provide seizure control for all patients while eliminating side effects. Improved specificity of intervention through on-demand approaches may overcome many of the limitations of current intervention strategies. This article reviews progress in seizure prediction and detection, potential new therapies to provide improved specificity, and devices to achieve these ends. Specifically, we discuss 1) potential signal modalities and algorithms for seizure detection and prediction, 2) closed-loop intervention approaches, and 3) hardware for implementing these algorithms and interventions. Seizure prediction and therapies maximize efficacy while minimizing side-effects through improved specificity may represent the future of epilepsy treatments. PMID:26035672

  4. Future of seizure prediction and intervention: closing the loop.

    PubMed

    Nagaraj, Vivek; Lee, Steven T; Krook-Magnuson, Esther; Soltesz, Ivan; Benquet, Pascal; Irazoqui, Pedro P; Netoff, Theoden I

    2015-06-01

    The ultimate goal of epilepsy therapies is to provide seizure control for all patients while eliminating side effects. Improved specificity of intervention through on-demand approaches may overcome many of the limitations of current intervention strategies. This article reviews the progress in seizure prediction and detection, potential new therapies to provide improved specificity, and devices to achieve these ends. Specifically, we discuss (1) potential signal modalities and algorithms for seizure detection and prediction, (2) closed-loop intervention approaches, and (3) hardware for implementing these algorithms and interventions. Seizure prediction and therapies maximize efficacy, whereas minimizing side effects through improved specificity may represent the future of epilepsy treatments. PMID:26035672

  5. Closed-loop endo-atmospheric ascent guidance for reusable launch vehicle

    NASA Astrophysics Data System (ADS)

    Sun, Hongsheng

    This dissertation focuses on the development of a closed-loop endo-atmospheric ascent guidance algorithm for the 2nd generation reusable launch vehicle. Special attention has been given to the issues that impact on viability, complexity and reliability in on-board implementation. The algorithm is called once every guidance update cycle to recalculate the optimal solution based on the current flight condition, taking into account atmospheric effects and path constraints. This is different from traditional ascent guidance algorithms which operate in a simple open-loop mode inside atmosphere, and later switch to a closed-loop vacuum ascent guidance scheme. The classical finite difference method is shown to be well suited for fast solution of the constrained optimal three-dimensional ascent problem. The initial guesses for the solutions are generated using an analytical vacuum optimal ascent guidance algorithm. Homotopy method is employed to gradually introduce the aerodynamic forces to generate the optimal solution from the optimal vacuum solution. The vehicle chosen for this study is the Lockheed Martin X-33 lifting-body reusable launch vehicle. To verify the algorithm presented in this dissertation, a series of open-loop and closed-loop tests are performed for three different missions. Wind effects are also studied in the closed-loop simulations. For comparison, the solutions for the same missions are also obtained by two independent optimization softwares. The results clearly establish the feasibility of closed-loop endo-atmospheric ascent guidance of rocket-powered launch vehicles. ATO cases are also tested to assess the adaptability of the algorithm to autonomously incorporate the abort modes.

  6. Heating and dynamics of two flare loop systems observed by AIA and EIS

    SciTech Connect

    Li, Y.; Ding, M. D.; Qiu, J.

    2014-02-01

    We investigate heating and evolution of flare loops in a C4.7 two-ribbon flare on 2011 February 13. From Solar Dynamics Observatory/Atmospheric Imaging Assembly (AIA) imaging observations, we can identify two sets of loops. Hinode/EUV Imaging Spectrometer (EIS) spectroscopic observations reveal blueshifts at the feet of both sets of loops. The evolution and dynamics of the two sets are quite different. The first set of loops exhibits blueshifts for about 25 minutes followed by redshifts, while the second set shows stronger blueshifts, which are maintained for about one hour. The UV 1600 observation by AIA also shows that the feet of the second set of loops brighten twice. These suggest that continuous heating may be present in the second set of loops. We use spatially resolved UV light curves to infer heating rates in the few tens of individual loops comprising the two loop systems. With these heating rates, we then compute plasma evolution in these loops with the 'enthalpy-based thermal evolution of loops' model. The results show that, for the first set of loops, the synthetic EUV light curves from the model compare favorably with the observed light curves in six AIA channels and eight EIS spectral lines, and the computed mean enthalpy flow velocities also agree with the Doppler shift measurements by EIS. For the second set of loops modeled with twice-heating, there are some discrepancies between modeled and observed EUV light curves in low-temperature bands, and the model does not fully produce the prolonged blueshift signatures as observed. We discuss possible causes for the discrepancies.

  7. SDO Sees Brightening Magnetic Loops

    NASA Video Gallery

    Two active regions sprouted arches of bundled magnetic loops in this video from NASA’s Solar Dynamics Observatory taken on Nov. 11-12, 2015. Charged particles spin along the magnetic field, tracing...

  8. SDO Sees Flourishing Magnetic Loops

    NASA Video Gallery

    A bright set of loops near the edge of the sun’s face grew and shifted quickly after the magnetic field was disrupted by a small eruption on Nov. 25, 2015. Charged particles emitting light in extre...

  9. Loop Electrosurgical Excision Procedure (LEEP)

    MedlinePlus

    ... that acts like a scalpel (surgical knife). An electric current is passed through the loop, which cuts away ... A procedure in which an instrument works with electric current to destroy tissue. Local Anesthesia: The use of ...

  10. Resolving the 180-degree ambiguity in vector magnetic field measurements: The 'minimum' energy solution

    NASA Technical Reports Server (NTRS)

    Metcalf, Thomas R.

    1994-01-01

    I present a robust algorithm that resolves the 180-deg ambiguity in measurements of the solar vector magnetic field. The technique simultaneously minimizes both the divergence of the magnetic field and the electric current density using a simulated annealing algorithm. This results in the field orientation with approximately minimum free energy. The technique is well-founded physically and is simple to implement.

  11. Observations of loops and prominences

    NASA Technical Reports Server (NTRS)

    Strong, Keith T.

    1994-01-01

    We review recent observations by the Yohkoh-SXT (Soft X-ray Telescope) in collaboration with other spacecraft and ground-based observatories of coronal loops and prominences. These new results point to problems that SoHO will be able to address. With a unique combination of rapid-cadence digital imaging (greater than or equal to 32 s full-disk and greater than or equal to 2 s partial-frame images), high spatial resolution (greater than or equal to 2.5 arcsec pixels), high sensitivity (EM less than or equal to 10(exp 42) cm(exp -3)), a low-scatter mirror, and large dynamic range, SXT can observe a vast range of targets on the Sun. Over the first 21 months of Yohkoh operations SXT has taken over one million images of the corona and so is building up an invaluable long-term database on the large-scale corona and loop geometry. The most striking thing about the SXT images is the range of loop sizes and shapes. The active regions are a bright tangle of magnetic field lines, surrounded by a network of large-scale quiet-Sun loops stretching over distances in excess of 105 km. The cross-section of most loops seems to be constant. Loops displaying significant Gamma's are the exception, not the rule, implying the presence of widespread currents in the corona. All magnetic structures show changes. Time scales range from seconds to months. The question of how these structures are formed, become filled with hot plasma, and are maintained is still open. While we see the propagation of brightenings along the length of active-region loops and in X-ray jets with velocities of several hundred km/s, much higher velocities are seen in the quiet Sun. In XBP flares, for example, velocities of over 1000 km/s are common. Active-region loops seem to be in constant motion, moving slowly outward, carrying plasma with them. During flares, loops often produce localized brightenings at the base and later at the apex of the loop. Quiescent filaments and prominences have been observed regularly

  12. Dynamical behaviour in coronal loops

    NASA Technical Reports Server (NTRS)

    Haisch, Bernhard M.

    1986-01-01

    Rapid variability has been found in two active region coronal loops observed by the X-ray Polychromator (XRP) and the Hard X-ray Imaging Spectrometer (HXIS) onboard the Solar Maximum Mission (SMM). There appear to be surprisingly few observations of the short-time scale behavior of hot loops, and the evidence presented herein lends support to the hypothesis that coronal heating may be impulsive and driven by flaring.

  13. Large scale tracking algorithms.

    SciTech Connect

    Hansen, Ross L.; Love, Joshua Alan; Melgaard, David Kennett; Karelitz, David B.; Pitts, Todd Alan; Zollweg, Joshua David; Anderson, Dylan Z.; Nandy, Prabal; Whitlow, Gary L.; Bender, Daniel A.; Byrne, Raymond Harry

    2015-01-01

    Low signal-to-noise data processing algorithms for improved detection, tracking, discrimination and situational threat assessment are a key research challenge. As sensor technologies progress, the number of pixels will increase signi cantly. This will result in increased resolution, which could improve object discrimination, but unfortunately, will also result in a significant increase in the number of potential targets to track. Many tracking techniques, like multi-hypothesis trackers, suffer from a combinatorial explosion as the number of potential targets increase. As the resolution increases, the phenomenology applied towards detection algorithms also changes. For low resolution sensors, "blob" tracking is the norm. For higher resolution data, additional information may be employed in the detection and classfication steps. The most challenging scenarios are those where the targets cannot be fully resolved, yet must be tracked and distinguished for neighboring closely spaced objects. Tracking vehicles in an urban environment is an example of such a challenging scenario. This report evaluates several potential tracking algorithms for large-scale tracking in an urban environment.

  14. Hinode XRT and EIS Multithermal Analysis of a Coronal Loop

    NASA Astrophysics Data System (ADS)

    Schmelz, Joan T.; Saar, S.; Kashyap, V.

    2010-05-01

    Data from the X-Ray Telescope (XRT) and the EUV Imaging Spectrometer (EIS) on Hinode were used to investigate the spatial and thermal properties of an isolated quiescent coronal loop. We constructed Differential Emission Measure (DEM) curves using Monte Carlo based reconstruction algorithms. We studied the loop as a whole, in segments, in transverse cuts, and point-by-point, always with some form of background subtraction, and find that the loop DEM is neither isothermal nor extremely broad, with 96% of the EM between 6.2 < log T < 6.7, and an EM weighted average temperature of log T = 6.48 +/- 0.16. We find evidence for a gradual change in temperature along the loop, with log T increasing by 0.1 from the footpoints to the peak. The combined XRT-EIS data can do a good job of constraining the temperature distribution for coronal loop plasma, but strong high- and low- temperature constraints are crucial. Solar physics research at the University of Memphis is supported by a Hinode subcontract from NASA/SAO as well as NSF ATM-0402729.

  15. Visualizations of coherent center domains in local Polyakov loops

    SciTech Connect

    Stokes, Finn M. Kamleh, Waseem; Leinweber, Derek B.

    2014-09-15

    Quantum Chromodynamics exhibits a hadronic confined phase at low to moderate temperatures and, at a critical temperature T{sub C}, undergoes a transition to a deconfined phase known as the quark–gluon plasma. The nature of this deconfinement phase transition is probed through visualizations of the Polyakov loop, a gauge independent order parameter. We produce visualizations that provide novel insights into the structure and evolution of center clusters. Using the HMC algorithm the percolation during the deconfinement transition is observed. Using 3D rendering of the phase and magnitude of the Polyakov loop, the fractal structure and correlations are examined. The evolution of the center clusters as the gauge fields thermalize from below the critical temperature to above it are also exposed. We observe deconfinement proceeding through a competition for the dominance of a particular center phase. We use stout-link smearing to remove small-scale noise in order to observe the large-scale evolution of the center clusters. A correlation between the magnitude of the Polyakov loop and the proximity of its phase to one of the center phases of SU(3) is evident in the visualizations. - Highlights: • We produce visualizations of center clusters in Polyakov loops. • The evolution of center clusters with HMC simulation time is examined. • Visualizations provide novel insights into the percolation of center clusters. • The magnitude and phase of the Polyakov loop are studied. • A correlation between the magnitude and center phase proximity is evident.

  16. ArchDB 2014: structural classification of loops in proteins

    PubMed Central

    Bonet, Jaume; Planas-Iglesias, Joan; Garcia-Garcia, Javier; Marín-López, Manuel A.; Fernandez-Fuentes, Narcis; Oliva, Baldo

    2014-01-01

    The function of a protein is determined by its three-dimensional structure, which is formed by regular (i.e. β-strands and α-helices) and non-periodic structural units such as loops. Compared to regular structural elements, non-periodic, non-repetitive conformational units enclose a much higher degree of variability—raising difficulties in the identification of regularities, and yet represent an important part of the structure of a protein. Indeed, loops often play a pivotal role in the function of a protein and different aspects of protein folding and dynamics. Therefore, the structural classification of protein loops is an important subject with clear applications in homology modelling, protein structure prediction, protein design (e.g. enzyme design and catalytic loops) and function prediction. ArchDB, the database presented here (freely available at http://sbi.imim.es/archdb), represents such a resource and has been an important asset for the scientific community throughout the years. In this article, we present a completely reworked and updated version of ArchDB. The new version of ArchDB features a novel, fast and user-friendly web-based interface, and a novel graph-based, computationally efficient, clustering algorithm. The current version of ArchDB classifies 149,134 loops in 5739 classes and 9608 subclasses. PMID:24265221

  17. Quantifying the Significance of Substructure in Coronal Loops

    NASA Astrophysics Data System (ADS)

    McKeough, K. B. D.; Kashyap, V.; McKillop, S.

    2014-12-01

    A method to infer the presence of small-scale substructure in SDO/AIA (Atmospheric Imaging Assembly on the Solar Dynamics Observatory) images of coronal loops is developed. We can classify visible loop structure based on this propensity to show substructure which puts constraints on contemporary solutions to the coronal heating problem. The method uses the Bayesian algorithm Low-count Image Reconstruction and Analysis (LIRA) to infer the multi-scale component of the loops which describes deviations from a smooth model. The increase in contrast of features in this multi-scale component is determined using a statistic that estimates the sharpness across the image. Regions with significant substructure are determined using p-value upper bounds. We are able to locate substructure visible in Hi-C (High-Resolution Coronal Imager) data that are not salient features in the corresponding AIA image. Looking at coronal loops at different regions of the Sun (e.g., low-lying structure and loops in the upper corona) we are able to map where detectable substructure exists and thus the influence of the nanoflare heating process. We acknowledge support from AIA under contract SP02H1701R from Lockheed-Martin to SAO.

  18. Resolving Conflicts in Middle Schools.

    ERIC Educational Resources Information Center

    Eddings, Evyonne

    1992-01-01

    Describes a lesson plan that explains the role of compromise as a method of resolving conflicts for use in a sixth-grade world cultures class. Includes activities, assessment, reteaching activities, and an extension project involving student skits. (DK)

  19. The Coronal Loop Inventory Project

    NASA Astrophysics Data System (ADS)

    Schmelz, J. T.; Pathak, S.; Christian, G. M.; Dhaliwal, R. S. S.; Paul, K. S.

    2015-11-01

    Most coronal physicists now seem to agree that loops are composed of tangled magnetic strands and have both isothermal and multithermal cross-field temperature distributions. As yet, however, there is no information on the relative importance of each of these categories, and we do not know how common one is with respect to the other. In this paper, we investigate these temperature properties for all loop segments visible in the 171-Å image of AR 11294, which was observed by the Atmospheric Imaging Assembly (AIA) on 2011 September 15. Our analysis revealed 19 loop segments, but only 2 of these were clearly isothermal. Six additional segments were effectively isothermal, that is, the plasma emission to which AIA is sensitive could not be distinguished from isothermal emission, within measurement uncertainties. One loop had both isothermal transition region and multithermal coronal solutions. Another five loop segments require multithermal plasma to reproduce the AIA observations. The five remaining loop segments could not be separated reliably from the background in the crucial non-171-Å AIA images required for temperature analysis. We hope that the direction of coronal heating models and the efforts modelers spend on various heating scenarios will be influenced by these results.

  20. The Structure of Coronal Loops

    NASA Technical Reports Server (NTRS)

    Antiochos, Spiro K.

    2009-01-01

    It is widely believed that the simple coronal loops observed by XUV imagers, such as EIT, TRACE, or XRT, actually have a complex internal structure consisting of many (perhaps hundreds) of unresolved, interwoven "strands". According to the nanoflare model, photospheric motions tangle the strands, causing them to reconnect and release the energy required to produce the observed loop plasma. Although the strands, themselves, are unresolved by present-generation imagers, there is compelling evidence for their existence and for the nanoflare model from analysis of loop intensities and temporal evolution. A problem with this scenario is that, although reconnection can eliminate some of the strand tangles, it cannot destroy helicity, which should eventually build up to observable scales. we consider, therefore, the injection and evolution of helicity by the nanoflare process and its implications for the observed structure of loops and the large-scale corona. we argue that helicity does survive and build up to observable levels, but on spatial and temporal scales larger than those of coronal loops. we discuss the implications of these results for coronal loops and the corona, in general .

  1. Combining Charge Couple Devices and Rate Sensors for the Feedforward Control System of a Charge Coupled Device Tracking Loop.

    PubMed

    Tang, Tao; Tian, Jing; Zhong, Daijun; Fu, Chengyu

    2016-01-01

    A rate feed forward control-based sensor fusion is proposed to improve the closed-loop performance for a charge couple device (CCD) tracking loop. The target trajectory is recovered by combining line of sight (LOS) errors from the CCD and the angular rate from a fiber-optic gyroscope (FOG). A Kalman filter based on the Singer acceleration model utilizes the reconstructive target trajectory to estimate the target velocity. Different from classical feed forward control, additive feedback loops are inevitably added to the original control loops due to the fact some closed-loop information is used. The transfer function of the Kalman filter in the frequency domain is built for analyzing the closed loop stability. The bandwidth of the Kalman filter is the major factor affecting the control stability and close-loop performance. Both simulations and experiments are provided to demonstrate the benefits of the proposed algorithm. PMID:27347970

  2. Combining Charge Couple Devices and Rate Sensors for the Feedforward Control System of a Charge Coupled Device Tracking Loop

    PubMed Central

    Tang, Tao; Tian, Jing; Zhong, Daijun; Fu, Chengyu

    2016-01-01

    A rate feed forward control-based sensor fusion is proposed to improve the closed-loop performance for a charge couple device (CCD) tracking loop. The target trajectory is recovered by combining line of sight (LOS) errors from the CCD and the angular rate from a fiber-optic gyroscope (FOG). A Kalman filter based on the Singer acceleration model utilizes the reconstructive target trajectory to estimate the target velocity. Different from classical feed forward control, additive feedback loops are inevitably added to the original control loops due to the fact some closed-loop information is used. The transfer function of the Kalman filter in the frequency domain is built for analyzing the closed loop stability. The bandwidth of the Kalman filter is the major factor affecting the control stability and close-loop performance. Both simulations and experiments are provided to demonstrate the benefits of the proposed algorithm. PMID:27347970

  3. Resolving local ambiguity using semantics of shape.

    SciTech Connect

    Diegert, Carl F.

    2010-05-01

    We demonstrate a new semantic method for automatic analysis of wide-area, high-resolution overhead imagery to tip and cue human intelligence analysts to human activity. In the open demonstration, we find and trace cars and rooftops. Our methodology, extended to analysis of voxels, may be applicable to understanding morphology and to automatic tracing of neurons in large-scale, serial-section TEM datasets. We defined an algorithm and software implementation that efficiently finds all combinations of image blobs that satisfy given shape semantics, where image blobs are formed as a general-purpose, first step that 'oversegments' image pixels into blobs of similar pixels. We will demonstrate the remarkable power (ROC) of this combinatorial-based work flow for automatically tracing any automobiles in a scene by applying semantics that require a subset of image blobs to fill out a rectangular shape, with width and height in given intervals. In most applications we find that the new combinatorial-based work flow produces alternative (overlapping) tracings of possible objects (e.g. cars) in a scene. To force an estimation (tracing) of a consistent collection of objects (cars), a quick-and-simple greedy algorithm is often sufficient. We will demonstrate a more powerful resolution method: we produce a weighted graph from the conflicts in all of our enumerated hypotheses, and then solve a maximal independent vertex set problem on this graph to resolve conflicting hypotheses. This graph computation is almost certain to be necessary to adequately resolve multiple, conflicting neuron topologies into a set that is most consistent with a TEM dataset.

  4. Resolving conflicts in water sharing: A systemic approach

    NASA Astrophysics Data System (ADS)

    Nandalal, K. D. W.; Simonovic, S. P.

    2003-12-01

    With industrial development and economic growth, conflicts over use and allocation of water have been increasing. Though diverse efforts have been made toward resolving conflicts through computer-based models, its clear understanding is prerequisite for models to be effective. A systems view illuminates how people think and consequences of their thoughts and actions on results and thus helps to achieve sustainable solutions. This paper presents a systemic approach to assist stakeholders in two different jurisdictions in a hypothetical water resource system to resolve a potential water-sharing conflict. A causal loop diagram developed provides an understanding of the conflict dynamics and feedback nature. A system dynamics simulation model developed fitting the causal diagram offers a significant opportunity to explore conflict's behavior and resolution with respect to final water allocations and time necessary to reach an agreement. The impact of initial aspiration, influence on system and struggle of stakeholders is discussed in detail.

  5. Algorithms for computing the multivariable stability margin

    NASA Technical Reports Server (NTRS)

    Tekawy, Jonathan A.; Safonov, Michael G.; Chiang, Richard Y.

    1989-01-01

    Stability margin for multiloop flight control systems has become a critical issue, especially in highly maneuverable aircraft designs where there are inherent strong cross-couplings between the various feedback control loops. To cope with this issue, we have developed computer algorithms based on non-differentiable optimization theory. These algorithms have been developed for computing the Multivariable Stability Margin (MSM). The MSM of a dynamical system is the size of the smallest structured perturbation in component dynamics that will destabilize the system. These algorithms have been coded and appear to be reliable. As illustrated by examples, they provide the basis for evaluating the robustness and performance of flight control systems.

  6. Approximate inference on planar graphs using loop calculus and belief progagation

    SciTech Connect

    Chertkov, Michael; Gomez, Vicenc; Kappen, Hilbert

    2009-01-01

    We introduce novel results for approximate inference on planar graphical models using the loop calculus framework. The loop calculus (Chertkov and Chernyak, 2006b) allows to express the exact partition function Z of a graphical model as a finite sum of terms that can be evaluated once the belief propagation (BP) solution is known. In general, full summation over all correction terms is intractable. We develop an algorithm for the approach presented in Chertkov et al. (2008) which represents an efficient truncation scheme on planar graphs and a new representation of the series in terms of Pfaffians of matrices. We analyze in detail both the loop series and the Pfaffian series for models with binary variables and pairwise interactions, and show that the first term of the Pfaffian series can provide very accurate approximations. The algorithm outperforms previous truncation schemes of the loop series and is competitive with other state-of-the-art methods for approximate inference.

  7. Loop quantum cosmology with self-dual variables

    NASA Astrophysics Data System (ADS)

    Wilson-Ewing, Edward

    2015-12-01

    Using the complex-valued self-dual connection variables, the loop quantum cosmology of a closed Friedmann space-time coupled to a massless scalar field is studied. It is shown how the reality conditions can be imposed in the quantum theory by choosing a particular inner product for the kinematical Hilbert space. While holonomies of the self-dual Ashtekar connection are not well defined in the kinematical Hilbert space, it is possible to introduce a family of generalized holonomylike operators of which some are well defined; these operators in turn are used in the definition of the Hamiltonian constraint operator where the scalar field can be used as a relational clock. The resulting quantum theory is closely related, although not identical, to standard loop quantum cosmology constructed from the Ashtekar-Barbero variables with a real Immirzi parameter. Effective Friedmann equations are derived which provide a good approximation to the full quantum dynamics for sharply peaked states whose volume remains much larger than the Planck volume, and they show that for these states quantum gravity effects resolve the big-bang and big-crunch singularities and replace them by a nonsingular bounce. Finally, the loop quantization in self-dual variables of a flat Friedmann space-time is recovered in the limit of zero spatial curvature and is identical to the standard loop quantization in terms of the real-valued Ashtekar-Barbero variables.

  8. Global far-ultraviolet properties of the Cygnus Loop

    SciTech Connect

    Kim, Il-Joong; Seon, Kwang-Il; Lee, Dae-Hee; Han, Wonyong; Lim, Yeo-Myeong; Min, Kyoung-Wook; Edelstein, Jerry

    2014-03-20

    We present the C III λ977, O VI λλ1032, 1038 and N IV] λ1486 emission line maps of the Cygnus Loop, obtained with the newly processed data of the Spectroscopy of Plasma Evolution from Astrophysical Radiation (SPEAR; also known as FIMS) mission. In addition, the Si IV+O IV] line complexes around 1400 Å are resolved into two separate emission lines whose intensity demonstrates a relatively high Si IV region that was predicted in the previous study. The morphological similarity between the O VI and X-ray images, as well as a comparison of the O VI intensity with the value expected from the X-ray results, indicates that large portions of the observed O VI emissions could be produced from X-ray emitting gas. Comparisons of the far-ultraviolet (FUV) images with the optical and H I 21 cm images reveal spatial variations of shock-velocity populations and high FUV extinction in the direction of a previously identified H I cloud. By calculating the FUV line ratios for several subregions of the Cygnus Loop, we investigate the spatial variation of the population of radiative shock velocities as well as the effects of resonance scattering, X-ray emitting gas, and nonradiative shocks. The FUV and X-ray luminosity comparisons between the Cygnus Loop and the Vela supernova remnant suggest that the fraction of shocks in the early evolutionary stages is much larger in the Cygnus Loop.

  9. Modeling and image reconstruction in spectrally resolved bioluminescence tomography

    NASA Astrophysics Data System (ADS)

    Dehghani, Hamid; Pogue, Brian W.; Davis, Scott C.; Patterson, Michael S.

    2007-02-01

    Recent interest in modeling and reconstruction algorithms for Bioluminescence Tomography (BLT) has increased and led to the general consensus that non-spectrally resolved intensity-based BLT results in a non-unique problem. However, the light emitted from, for example firefly Luciferase, is widely distributed over the band of wavelengths from 500 nm to 650 nm and above, with the dominant fraction emitted from tissue being above 550 nm. This paper demonstrates the development of an algorithm used for multi-wavelength 3D spectrally resolved BLT image reconstruction in a mouse model. It is shown that using a single view data, bioluminescence sources of up to 15 mm deep can be successfully recovered given correct information about the underlying tissue absorption and scatter.

  10. Pulse retrieval in frequency-resolved optical gating based on the method of generalized projections

    SciTech Connect

    DeLong, K.W.; Fittinghoff, D.N.; Trebino, R. ); Kohler, B.; Wilson, K. )

    1994-12-15

    We use the algorithmic method of generalized projections (GP's) to retrieve the intensity and phase of an ultrashort laser pulse from the experimental trace in frequency-resolved optical gating (FROG). Using simulations, we show that the use of GP's improves significantly the convergence properties of the algorithm over the basic FROG algorithm. In experimental measurements, the GP-based algorithm achieves significantly lower errors than previous algorithms. The use of GP's also permits the inclusion of an arbitrary material response function in the FROG problem.

  11. Loop Quantum Cosmology: holonomy corrections to inflationary models

    SciTech Connect

    Artymowski, Michal; Lalak, Zygmunt; Szulc, Lukasz

    2009-01-15

    In the recent years the quantization methods of Loop Quantum Gravity have been successfully applied to the homogeneous and isotropic Friedmann-Robertson-Walker space-times. The resulting theory, called Loop Quantum Cosmology (LQC), resolves the Big Bang singularity by replacing it with the Big Bounce. We argue that the LQC holonomy corrections generate also certain corrections to field theoretical inflationary scenarios. These corrections imply that in the LQC the effective sonic horizon becomes infinite at some point after the bounce and that the scale of the inflationary potential implied by the COBE normalisation increases. The evolution of scalar fields immediately after the Bounce becomes modified in an interesting way. We point out that one can use COBE normalisation to establish an upper bound on the quantum of length of LQG. LQC corrections other than the holonomy one are assumed to be subdominant.

  12. Compaction and segregation of sister chromatids via active loop extrusion

    PubMed Central

    Goloborodko, Anton; Imakaev, Maxim V; Marko, John F; Mirny, Leonid

    2016-01-01

    The mechanism by which chromatids and chromosomes are segregated during mitosis and meiosis is a major puzzle of biology and biophysics. Using polymer simulations of chromosome dynamics, we show that a single mechanism of loop extrusion by condensins can robustly compact, segregate and disentangle chromosomes, arriving at individualized chromatids with morphology observed in vivo. Our model resolves the paradox of topological simplification concomitant with chromosome 'condensation', and explains how enzymes a few nanometers in size are able to control chromosome geometry and topology at micron length scales. We suggest that loop extrusion is a universal mechanism of genome folding that mediates functional interactions during interphase and compacts chromosomes during mitosis. DOI: http://dx.doi.org/10.7554/eLife.14864.001 PMID:27192037

  13. Instanton calculus and loop operator in supersymmetric gauge theory

    SciTech Connect

    Kanno, Hiroaki; Moriyama, Sanefumi

    2008-06-15

    We compute the one-point function of the glueball loop operator in the maximally confining phase of supersymmetric gauge theory using instanton calculus. In the maximally confining phase the residual symmetry is the diagonal U(1) subgroup and the localization formula implies that the chiral correlation functions are the sum of the contributions from each fixed point labeled by the Young diagram. The summation can be performed exactly by operator formalism of free fermions, which is also featured in the equivariant Gromov-Witten theory of P{sup 1}. By taking the Laplace transformation of the glueball loop operator, we find an exact agreement with the previous results for the generating function (resolvent) of the glueball one-point functions.

  14. Kalman Orbit Optimized Loop Tracking

    NASA Technical Reports Server (NTRS)

    Young, Lawrence E.; Meehan, Thomas K.

    2011-01-01

    Under certain conditions of low signal power and/or high noise, there is insufficient signal to noise ratio (SNR) to close tracking loops with individual signals on orbiting Global Navigation Satellite System (GNSS) receivers. In addition, the processing power available from flight computers is not great enough to implement a conventional ultra-tight coupling tracking loop. This work provides a method to track GNSS signals at very low SNR without the penalty of requiring very high processor throughput to calculate the loop parameters. The Kalman Orbit-Optimized Loop (KOOL) tracking approach constitutes a filter with a dynamic model and using the aggregate of information from all tracked GNSS signals to close the tracking loop for each signal. For applications where there is not a good dynamic model, such as very low orbits where atmospheric drag models may not be adequate to achieve the required accuracy, aiding from an IMU (inertial measurement unit) or other sensor will be added. The KOOL approach is based on research JPL has done to allow signal recovery from weak and scintillating signals observed during the use of GPS signals for limb sounding of the Earth s atmosphere. That approach uses the onboard PVT (position, velocity, time) solution to generate predictions for the range, range rate, and acceleration of the low-SNR signal. The low- SNR signal data are captured by a directed open loop. KOOL builds on the previous open loop tracking by including feedback and observable generation from the weak-signal channels so that the MSR receiver will continue to track and provide PVT, range, and Doppler data, even when all channels have low SNR.

  15. Fabrication techniques for superconducting readout loops

    NASA Technical Reports Server (NTRS)

    Payne, J. E.

    1982-01-01

    Procedures for the fabrication of superconducting readout loops out of niobium on glass substrates were developed. A computer program for an existing fabrication system was developed. Both positive and negative resist procedures for the production of the readout loops were investigated. Methods used to produce satisfactory loops are described and the various parameters affecting the performance of the loops are analyzed.

  16. Filter for third order phase locked loops

    NASA Technical Reports Server (NTRS)

    Crow, R. B.; Tausworthe, R. C. (Inventor)

    1973-01-01

    Filters for third-order phase-locked loops are used in receivers to acquire and track carrier signals, particularly signals subject to high doppler-rate changes in frequency. A loop filter with an open-loop transfer function and set of loop constants, setting the damping factor equal to unity are provided.

  17. Refinement of thermal imager minimum resolvable temperature difference calculating method

    NASA Astrophysics Data System (ADS)

    Kolobrodov, V. G.; Mykytenko, V. I.

    2015-11-01

    Calculating methods, which accurately predict minimum resolvable temperature difference (MRTD), are of significant interest for many years. The article deals with improvement the accuracy of determining the thermal imaging system MRTD by elaboration the visual perception model. We suggest MRTD calculating algorithm, which is based on a reliable approximation of the human visual system modulation transfer function (MTF) proposed by N. Nill. There was obtained a new expression for the bandwidth evaluation, which is independent of angular size of the Foucault bar target.

  18. Study of the Open Loop and Closed Loop Oscillator Techniques

    SciTech Connect

    Imel, George R.; Baker, Benjamin; Riley, Tony; Langbehn, Adam; Aryal, Harishchandra; Benzerga, M. Lamine

    2015-04-11

    This report presents the progress and completion of a five-year study undertaken at Idaho State University of the measurement of very small worth reactivity samples comparing open and closed loop oscillator techniques.The study conclusively demonstrated the equivalency of the two techniques with regard to uncertainties in reactivity values, i.e., limited by reactor noise. As those results are thoroughly documented in recent publications, in this report we will concentrate on the support work that was necessary. For example, we describe in some detail the construction and calibration of a pilot rod for the closed loop system. We discuss the campaign to measure the required reactor parameters necessary for inverse-kinetics. Finally, we briefly discuss the transfer of the open loop technique to other reactor systems.

  19. Algorithm development

    NASA Technical Reports Server (NTRS)

    Barth, Timothy J.; Lomax, Harvard

    1987-01-01

    The past decade has seen considerable activity in algorithm development for the Navier-Stokes equations. This has resulted in a wide variety of useful new techniques. Some examples for the numerical solution of the Navier-Stokes equations are presented, divided into two parts. One is devoted to the incompressible Navier-Stokes equations, and the other to the compressible form.

  20. Exploring the energy landscapes of flexible molecular loops using higher-dimensional continuation.

    PubMed

    Porta, Josep M; Jaillet, Léonard

    2013-01-30

    The conformational space of a flexible molecular loop includes the set of conformations fulfilling the geometric loop-closure constraints and its energy landscape can be seen as a scalar field defined on this implicit set. Higher-dimensional continuation tools, recently developed in dynamical systems and also applied to robotics, provide efficient algorithms to trace out implicitly defined sets. This article describes these tools and applies them to obtain full descriptions of the energy landscapes of short molecular loops that, otherwise, can only be partially explored, mainly via sampling. Moreover, to deal with larger loops, this article exploits the higher-dimensional continuation tools to find local minima and minimum energy transition paths between them, without deviating from the loop-closure constraints. The proposed techniques are applied to previously studied molecules revealing the intricate structure of their energy landscapes. PMID:23015474

  1. Gluing hexagons at three loops

    NASA Astrophysics Data System (ADS)

    Basso, Benjamin; Goncalves, Vasco; Komatsu, Shota; Vieira, Pedro

    2016-06-01

    We perform extensive three-loop tests of the hexagon bootstrap approach for structure constants in planar N = 4 SYM theory. We focus on correlators involving two BPS operators and one non-BPS operator in the so-called SL (2) sector. At three loops, such correlators receive wrapping corrections from mirror excitations flowing in either the adjacent or the opposing channel. Amusingly, we find that the first type of correction coincides exactly with the leading wrapping correction for the spectrum (divided by the one-loop anomalous dimension). We develop an efficient method for computing the second type of correction for operators with any spin. The results are in perfect agreement with the recently obtained three-loop perturbative data by Chicherin, Drummond, Heslop, Sokatchev [2] and by Eden [3]. We also derive the integrand for general multi-particle wrapping corrections, which turns out to take a remarkably simple form. As an application we estimate the loop order at which various new physical effects are expected to kick-in.

  2. Resolving the Issues with Flywheel Position Sensors

    NASA Technical Reports Server (NTRS)

    Fehrmann, Elizabeth A.

    2004-01-01

    For the past few years, the Advanced Electrical Systems Branch here at NASA Glenn has been pursuing research in the area of flywheels. The purpose of these pursuits has been t o explore the potential for flywheels to replace current battery-powered systems in space. So far it has been learned that flywheels offer large momentum storage capacity, comparatively small volume, high durability, and near- complete discharge capabilities, all of which are advancements over the existing nickel hydrogen and nickel cadmium batteries. Another significant advantage of flywheels is the potential they offer for combining the function of attitude control with energy storage. During the summer of 2004, I worked with Dr. Barbara Kenny in the Advanced Electrical Systems Branch, supporting the work she is doing by analyzing and testing some new components for the new Generation-2 flywheel. To monitor the speed and angular position of the flywheel rotor, a once-around (OAR) signal along with a sensorless algorithm is used. The OAR signal is used for the magnetic bearings that keep the flywheel suspended for frictionless operation. The sensorless algorithm is used for the flywheel motor/generator control. The OAR is generated from position sensors that monitor a circular plate. The plate has a cut down the middle such that one half of the circle is on a slightly lower level than the other. Every half-turn, or 180, the sensors detect the "cut" on the plate, and trigger the OAR, telling the computer that the rotor has made half a revolution. This, however, doesn't provide needed detailed information about the angular position of the rotor, since it only provides a signal alert every half- revolution. This is enough information for the magnetic bearing control but is insufficient for the motor/generator control. A new resolver was designed such that it would give continuous angle information rather than the 180 degree information of the OAR. The new resolver has two separate observable

  3. Bandwidth controller for phase-locked-loop

    NASA Technical Reports Server (NTRS)

    Brockman, Milton H. (Inventor)

    1992-01-01

    A phase locked loop utilizing digital techniques to control the closed loop bandwidth of the RF carrier phase locked loop in a receiver provides high sensitivity and a wide dynamic range for signal reception. After analog to digital conversion, a digital phase locked loop bandwidth controller provides phase error detection with automatic RF carrier closed loop tracking bandwidth control to accommodate several modes of transmission.

  4. Phenomenological loop quantum geometry of the Schwarzschild black hole

    SciTech Connect

    Chiou, D.-W.

    2008-09-15

    The interior of a Schwarzschild black hole is investigated at the level of phenomenological dynamics with the discreteness corrections of loop quantum geometry implemented in two different improved quantization schemes. In one scheme, the classical black hole singularity is resolved by the quantum bounce, which bridges the black hole interior with a white hole interior. In the other scheme, the classical singularity is resolved and the event horizon is also diffused by the quantum bounce. Jumping over the quantum bounce, the black hole gives birth to a baby black hole with a much smaller mass. This lineage continues as each classical black hole brings forth its own descendant in the consecutive classical cycle, giving the whole extended spacetime fractal structure, until the solution eventually descends into the deep Planck regime, signaling a breakdown of the semiclassical description. The issues of scaling symmetry and no-hair theorem are also discussed.

  5. A compensatory algorithm for the slow-down effect on constant-time-separation approaches

    NASA Technical Reports Server (NTRS)

    Abbott, Terence S.

    1991-01-01

    In seeking methods to improve airport capacity, the question arose as to whether an electronic display could provide information which would enable the pilot to be responsible for self-separation under instrument conditions to allow for the practical implementation of reduced separation, multiple glide path approaches. A time based, closed loop algorithm was developed and simulator validated for in-trail (one aircraft behind the other) approach and landing. The algorithm was designed to reduce the effects of approach speed reduction prior to landing for the trailing aircraft as well as the dispersion of the interarrival times. The operational task for the validation was an instrument approach to landing while following a single lead aircraft on the same approach path. The desired landing separation was 60 seconds for these approaches. An open loop algorithm, previously developed, was used as a basis for comparison. The results showed that relative to the open loop algorithm, the closed loop one could theoretically provide for a 6 pct. increase in runway throughput. Also, the use of the closed loop algorithm did not affect the path tracking performance and pilot comments indicated that the guidance from the closed loop algorithm would be acceptable from an operational standpoint. From these results, it is concluded that by using a time based, closed loop spacing algorithm, precise interarrival time intervals may be achievable with operationally acceptable pilot workload.

  6. Reactive Collision Avoidance Algorithm

    NASA Technical Reports Server (NTRS)

    Scharf, Daniel; Acikmese, Behcet; Ploen, Scott; Hadaegh, Fred

    2010-01-01

    -line. The optimal avoidance trajectory is implemented as a receding-horizon model predictive control law. Therefore, at each time step, the optimal avoidance trajectory is found and the first time step of its acceleration is applied. At the next time step of the control computer, the problem is re-solved and the new first time step is again applied. This continual updating allows the RCA algorithm to adapt to a colliding spacecraft that is making erratic course changes.

  7. Digital phase-lock loop

    NASA Technical Reports Server (NTRS)

    Thomas, Jr., Jess B. (Inventor)

    1991-01-01

    An improved digital phase lock loop incorporates several distinctive features that attain better performance at high loop gain and better phase accuracy. These features include: phase feedback to a number-controlled oscillator in addition to phase rate; analytical tracking of phase (both integer and fractional cycles); an amplitude-insensitive phase extractor; a more accurate method for extracting measured phase; a method for changing loop gain during a track without loss of lock; and a method for avoiding loss of sampled data during computation delay, while maintaining excellent tracking performance. The advantages of using phase and phase-rate feedback are demonstrated by comparing performance with that of rate-only feedback. Extraction of phase by the method of modeling provides accurate phase measurements even when the number-controlled oscillator phase is discontinuously updated.

  8. Criteria for saturated magnetization loop

    NASA Astrophysics Data System (ADS)

    Harres, A.; Mikhov, M.; Skumryev, V.; Andrade, A. M. H. de; Schmidt, J. E.; Geshev, J.

    2016-03-01

    Proper estimation of magnetization curve parameters is vital in studying magnetic systems. In the present article, criteria for discrimination non-saturated (minor) from saturated (major) hysteresis loops are proposed. These employ the analysis of (i) derivatives of both ascending and descending branches of the loop, (ii) remanent magnetization curves, and (iii) thermomagnetic curves. Computational simulations are used in order to demonstrate their validity. Examples illustrating the applicability of these criteria to well-known real systems, namely Fe3O4 and Ni fine particles, are provided. We demonstrate that the anisotropy-field value estimated from a visual examination of an only apparently major hysteresis loop could be more than two times lower than the real one.

  9. Waves in Solar Coronal Loops

    NASA Astrophysics Data System (ADS)

    Wang, T. J.

    2016-02-01

    The corona is visible in the optical band only during a total solar eclipse or with a coronagraph. Coronal loops are believed to be plasma-filled closed magnetic flux anchored in the photosphere. Based on the temperature regime, they are generally classified into cool, warm, and hot loops. The magnetized coronal structures support propagation of various types of magnetohydrodynamics (MHD) waves. This chapter reviews the recent progress made in studies based on observations of four types of wave phenomena mainly occurring in coronal loops of active regions, including: flare-excited slow-mode waves; impulsively excited kink-mode waves; propagating slow magnetoacoustic waves; and ubiquitous propagating kink (Alfvénic) waves. This review not only comprehensively discusses these waves and coronal seismology but also topics that are newly emerging or hotly debated in order to provide the reader with useful guidance on further studies.

  10. Resolvability of positron decay channels

    SciTech Connect

    Fluss, M.J.; Howell, R.H.; Rosenberg, I.J.; Meyer, P.

    1985-03-07

    Many data analysis treatments of positron experiments attempt to resolve two or more positron decay or exist channels which may be open simultaneously. Examples of the need to employ such treatments of the experimental results can be found in the resolution of the constituents of a defect ensemble, or in the analysis of the complex spectra which arise from the interaction of slow positrons at or near the surfaces of solids. Experimental one- and two-dimensional angular correlation of annihilation radiation experiments in Al single crystals have shown that two defect species (mono- and divacancies) can be resolved under suitable conditions. Recent experiments at LLNL indicate that there are a variety of complex exit channels open to positrons interacting at surfaces, and ultimely these decay channels must also be suitably resolved from one another. 6 refs., 4 figs.

  11. Evaluation of feedback-reduction algorithms for hearing aids.

    PubMed

    Greenberg, J E; Zurek, P M; Brantley, M

    2000-11-01

    Three adaptive feedback-reduction algorithms were implemented in a laboratory-based digital hearing aid system and evaluated with dynamic feedback paths and hearing-impaired subjects. The evaluation included measurements of maximum stable gain and subjective quality ratings. The continuously adapting CNN algorithm (Closed-loop processing with No probe Noise) provided the best performance: 8.5 dB of added stable gain (ASG) relative to a reference algorithm averaged over all subjects, ears, and vent conditions. Two intermittently adapting algorithms, ONO (Open-loop with Noise when Oscillation detected) and ONQ (Open-loop with Noise when Quiet detected), provided an average of 5 dB of ASG. Subjects with more severe hearing losses received greater benefits: 13 dB average ASG for the CNN algorithm and 7-8 dB average ASG for the ONO and ONQ algorithms. These values are conservative estimates of ASG because the fitting procedure produced a frequency-gain characteristic that already included precautions against feedback. Speech quality ratings showed no substantial algorithm effect on pleasantness or intelligibility, although subjects informally expressed strong objections to the probe noise used by the ONO and ONQ algorithms. This objection was not reflected in the speech quality ratings because of limitations of the experimental procedure. The results clearly indicate that the CNN algorithm is the most promising choice for adaptive feedback reduction in hearing aids. PMID:11108377

  12. All digital pulsewidth control loop

    NASA Astrophysics Data System (ADS)

    Huang, Hong-Yi; Jan, Shiun-Dian; Pu, Ruei-Iun

    2013-03-01

    This work presents an all-digital pulsewidth control loop (ADPWCL). The proposed system accepts a wide range of input duty cycles and performs a fast correction to the target output pulsewidth. An all-digital delay-locked loop (DLL) with fast locking time using a simplified time to digital converter and a new differential two-step delay element is proposed. The area of the delay element is much smaller than that in conventional designs, while having the same delay range. A test chip is verified in a 0.18-µm CMOS process. The measured duty cycle ranges from 4% to 98% with 7-bit resolution.

  13. Loop quantum cosmology: an overview

    NASA Astrophysics Data System (ADS)

    Ashtekar, Abhay

    2009-04-01

    A brief overview of loop quantum cosmology of homogeneous isotropic models is presented with emphasis on the origin of and subtleties associated with the resolution of big bang and big crunch singularities. These results bear out the remarkable intuition that John Wheeler had. Discussion is organized at two levels. The the main text provides a bird’s eye view of the subject that should be accessible to non-experts. Appendices address conceptual and technical issues that are often raised by experts in loop quantum gravity and string theory.

  14. Modeling of compact loop antennas

    NASA Astrophysics Data System (ADS)

    Baity, F. W.

    1987-09-01

    A general compact loop antenna model which treats all elements of the antenna as lossy transmission lines has been developed. In addition to capacitively tuned resonant double loop (RDL) antennas, the model treats sub-tuned RDL antennas. Calculations using the model have been compared with measurements on full-scale mock-ups of RDL antennas for ATF and TFTR in order to refine the transmission line parameters. Results from the model are presented for RDL antenna designs for ATF, TFTR, Tore Supra, and the Compact Ignition Tokamak (CIT).

  15. Many Ways to Loop DNA

    PubMed Central

    Griffith, Jack D.

    2013-01-01

    In the 1960s, I developed methods for directly visualizing DNA and DNA-protein complexes using an electron microscope. This made it possible to examine the shape of DNA and to visualize proteins as they fold and loop DNA. Early applications included the first visualization of true nucleosomes and linkers and the demonstration that repeating tracts of adenines can cause a curvature in DNA. The binding of DNA repair proteins, including p53 and BRCA2, has been visualized at three- and four-way junctions in DNA. The trombone model of DNA replication was directly verified, and the looping of DNA at telomeres was discovered. PMID:24005675

  16. Cervical Radiculopathy Caused by Vertebral Artery Loop Formation : A Case Report and Review of the Literature

    PubMed Central

    Kim, Hoon Soo; Cheh, Gene; Lee, Sang-Ho

    2010-01-01

    Vertebral artery loop formation causing encroachment on cervical neural foramen and canal is a rare cause of cervical radiculopathy. We report a case of 61-year-old woman with vertebral artery loop formation who presented with right shoulder pain radiating to her arm for 2 years. Plain radiograph and computed tomography scan revealed widening of the right intervertebral foramen at the C5-6 level. Magnetic resonance imaging and angiogram confirmed the vertebral artery loop formation compressing the right C6 nerve root. We had considered microdecompressive surgery, but the patient's symptoms resolved after conservative management. Clinician should keep in mind that vertebral artery loop formation is one of important causes of cervical radiculopathy. Vertebral artery should be visualized using magnetic resonance angiography in suspected case. PMID:21286489

  17. A coordinate axis transformation study of spatial QRS loop in hypertrophic cardiomyopathy.

    PubMed

    Takimiya, A; Nakajima, S; Mugikura, M; Mutoh, K; Ibukiyama, C

    1991-01-01

    To obtain an overall view of the QRS loop on vectorcardiograms (VCG) of hypertrophic cardiomyopathy (HCM), the coordinate axis was transformed using the resolver method. The morphological features and planarity of the loop were compared with hypertrophic patterns and hypertensive heart disease (HHD). The subjects in the present study included 30 normal individuals, 40 patients with HCM and 30 with HHD. The HHD group was selected from patients showing left ventricular hypertrophy on VCG similar to that of HCM patients. The HCM group showed significantly greater values than the HHD group in the thickness/length ratio, which represents the planarity of the spatial QRS loop. The above finding suggests that the HCM group had greater deformation in the QRS loop than the HHD group. This may provide a useful indicator for the differential diagnosis of the two diseases. PMID:1920958

  18. Empirical Measurements of Loop Structures in the Sun's Transition Region Compared with Energy Balance Models

    NASA Astrophysics Data System (ADS)

    Chesny, David; Oluseyi, H. M.; Orange, N. B.; DeBoth, D.; Preuss, L.; Neira, C.; Ebert, M.; Cohen, L.

    2011-01-01

    We have measured the properties of solar upper transition region loop structures barely resolvable in 1-arcsecond resolution data from the Transition Region and Coronal Explorer (TRACE) satellite and from the Solar Ultraviolet Measurements of Emitted Radiation (SUMER) instrument aboard the SOHO satellite for the purpose of investigating the mechanisms that generate and energize these structures. The images were wavelet transformed to elucidate and isolate fine-scale loops, whose lengths, widths, emergent flux, flows, and underlying magnetic field were measured. It was found that the loops' magnetic geometries were well-fit by potential field models. However, hydrostatic models were unable to self-consistently reproduce the loop's observed properties for a wide range of parameter space.

  19. Loop quantization of vacuum Bianchi I cosmology

    SciTech Connect

    Martin-Benito, M.; Mena Marugan, G. A.; Pawlowski, T.

    2008-09-15

    We analyze the loop quantization of the family of vacuum Bianchi I spacetimes, a gravitational system of which classical solutions describe homogeneous anisotropic cosmologies. We rigorously construct the operator that represents the Hamiltonian constraint, showing that the states of zero volume completely decouple from the rest of quantum states. This fact ensures that the classical cosmological singularity is resolved in the quantum theory. In addition, this allows us to adopt an equivalent quantum description in terms of a well-defined densitized Hamiltonian constraint. This latter constraint can be regarded in a certain sense as a difference evolution equation in an internal time provided by one of the triad components, which is polymerically quantized. Generically, this evolution equation is a relation between the projection of the quantum states in three different sections of constant internal time. Nevertheless, around the initial singularity the equation involves only the two closest sections with the same orientation of the triad. This has a double effect: on the one hand, physical states are determined just by the data on one section, on the other hand, the evolution defined in this way never crosses the singularity, without the need of any special boundary condition. Finally, we determine the inner product and the physical Hilbert space employing group averaging techniques, and we specify a complete algebra of Dirac observables. This completes the quantization program.

  20. Resolution of singularities for multi-loop integrals

    NASA Astrophysics Data System (ADS)

    Bogner, Christian; Weinzierl, Stefan

    2008-04-01

    We report on a program for the numerical evaluation of divergent multi-loop integrals. The program is based on iterated sector decomposition. We improve the original algorithm of Binoth and Heinrich such that the program is guaranteed to terminate. The program can be used to compute numerically the Laurent expansion of divergent multi-loop integrals regulated by dimensional regularisation. The symbolic and the numerical steps of the algorithm are combined into one program. Program summaryProgram title: sector_decomposition Catalogue identifier: AEAG_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEAG_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 47 506 No. of bytes in distributed program, including test data, etc.: 328 485 Distribution format: tar.gz Programming language: C++ Computer: all Operating system: Unix RAM: Depending on the complexity of the problem Classification: 4.4 External routines: GiNaC, available from http://www.ginac.de, GNU scientific library, available from http://www.gnu.org/software/gsl Nature of problem: Computation of divergent multi-loop integrals. Solution method: Sector decomposition. Restrictions: Only limited by the available memory and CPU time. Running time: Depending on the complexity of the problem.

  1. Closed-loop thrust and pressure profile throttling of a nitrous oxide/hydroxyl-terminated polybutadiene hybrid rocket motor

    NASA Astrophysics Data System (ADS)

    Peterson, Zachary W.

    Hybrid motors that employ non-toxic, non-explosive components with a liquid oxidizer and a solid hydrocarbon fuel grain have inherently safe operating characteristics. The inherent safety of hybrid rocket motors offers the potential to greatly reduce overall operating costs. Another key advantage of hybrid rocket motors is the potential for in-flight shutdown, restart, and throttle by controlling the pressure drop between the oxidizer tank and the injector. This research designed, developed, and ground tested a closed-loop throttle controller for a hybrid rocket motor using nitrous oxide and hydroxyl-terminated polybutadiene as propellants. The research simultaneously developed closed-loop throttle algorithms and lab scale motor hardware to evaluate the fidelity of the throttle simulations and algorithms. Initial open-loop motor tests were performed to better classify system parameters and to validate motor performance values. Deep-throttle open-loop tests evaluated limits of stable thrust that can be achieved on the test hardware. Open-loop tests demonstrated the ability to throttle the motor to less than 10% of maximum thrust with little reduction in effective specific impulse and acoustical stability. Following the open-loop development, closed-loop, hardware-in-the-loop tests were performed. The closed-loop controller successfully tracked prescribed step and ramp command profiles with a high degree of fidelity. Steady-state accuracy was greatly improved over uncontrolled thrust.

  2. Tracking filter algorithm for automatic video tracking

    NASA Astrophysics Data System (ADS)

    McEver, Mark A.; Kimbrell, James E.

    2006-05-01

    In addition to servo control and power amplification, motion control systems for optical tracking pedestals feature capabilities such as electro-optical tracking using an integrated Automatic Video Tracker (AVT) card. An electro-optical system tracking loop is comprised of sensors mounted on a pointing pedestal, an AVT that detects a target in the sensor imagery, and a tracking filter algorithm that commands the pedestal to follow the target. The tracking filter algorithm receives the target boresight error from the AVT and calculates motion demands for the pedestal servo controller. This paper presents a tracking algorithm based on target state estimation using a Kalman filter. The servo demands are based on calculating the Kalman filter state estimate from absolute line-of-sight angles to the target. Simulations are used to compare its performance to tracking loops without tracking filters, and to other tracking filter algorithms, such as rate feedback loops closed around boresight error. Issues such as data latency and sensor alignment error are discussed.

  3. TIME-RESOLVED VIBRATIONAL SPECTROSCOPY

    SciTech Connect

    Andrei Tokmakoff, MIT; Paul Champion, Northeastern University; Edwin J. Heilweil, NIST; Keith A. Nelson, MIT; Larry Ziegler, Boston University

    2009-05-14

    This document contains the Proceedings from the 14th International Conference on Time-Resolved Vibrational Spectroscopy, which was held in Meredith, NH from May 9-14, 2009. The study of molecular dynamics in chemical reaction and biological processes using time-resolved spectroscopy plays an important role in our understanding of energy conversion, storage, and utilization problems. Fundamental studies of chemical reactivity, molecular rearrangements, and charge transport are broadly supported by the DOE’s Office of Science because of their role in the development of alternative energy sources, the understanding of biological energy conversion processes, the efficient utilization of existing energy resources, and the mitigation of reactive intermediates in radiation chemistry. In addition, time-resolved spectroscopy is central to all five of DOE’s grand challenges for fundamental energy science. The Time-Resolved Vibrational Spectroscopy conference is organized biennially to bring the leaders in this field from around the globe together with young scientists to discuss the most recent scientific and technological advances. The latest technology in ultrafast infrared, Raman, and terahertz spectroscopy and the scientific advances that these methods enable were covered. Particular emphasis was placed on new experimental methods used to probe molecular dynamics in liquids, solids, interfaces, nanostructured materials, and biomolecules.

  4. Resolving Ethical Issues at School

    ERIC Educational Resources Information Center

    Benninga, Jacques S.

    2013-01-01

    Although ethical dilemmas are a constant in teachers' lives, the profession has offered little in the way of training to help teachers address such issues. This paper presents a framework, based on developmental theory, for resolving professional ethical dilemmas. The Four-Component Model of Moral Maturity, when used in conjunction with a…

  5. Virginia Resolves, 1993-1994.

    ERIC Educational Resources Information Center

    Morrow, S. Rex, Ed.

    1994-01-01

    These two issues of "Virginia Resolves" provide articles of interest to the social studies reader and provides ideas for social studies instruction and curriculum. The fall issue features seven articles: (1) "Death and the Young Child" (Rosanne J. Marek); (2) "Simulations: Bibliography for the Middle and Elementary Teachers" (William Coleman Redd…

  6. An Overview of LISA Data Analysis Algorithms

    NASA Astrophysics Data System (ADS)

    Porter, Edward K.

    2009-07-01

    The development of search algorithms for gravitational wave sources in the LISA data stream is currently a very active area of research. It has become clear that not only does difficulty lie in searching for the individual sources, but in the case of galactic binaries, evaluating the fidelity of resolved sources also turns out to be a major challenge in itself. In this article we review the current status of developed algorithms for galactic binary, non-spinning supermassive black hole binary and extreme mass ratio inspiral sources. While covering the vast majority of algorithms, we will highlight those that represent the state of the art in terms of speed and accuracy.

  7. Closed-Loop Neuromorphic Benchmarks

    PubMed Central

    Stewart, Terrence C.; DeWolf, Travis; Kleinhans, Ashley; Eliasmith, Chris

    2015-01-01

    Evaluating the effectiveness and performance of neuromorphic hardware is difficult. It is even more difficult when the task of interest is a closed-loop task; that is, a task where the output from the neuromorphic hardware affects some environment, which then in turn affects the hardware's future input. However, closed-loop situations are one of the primary potential uses of neuromorphic hardware. To address this, we present a methodology for generating closed-loop benchmarks that makes use of a hybrid of real physical embodiment and a type of “minimal” simulation. Minimal simulation has been shown to lead to robust real-world performance, while still maintaining the practical advantages of simulation, such as making it easy for the same benchmark to be used by many researchers. This method is flexible enough to allow researchers to explicitly modify the benchmarks to identify specific task domains where particular hardware excels. To demonstrate the method, we present a set of novel benchmarks that focus on motor control for an arbitrary system with unknown external forces. Using these benchmarks, we show that an error-driven learning rule can consistently improve motor control performance across a randomly generated family of closed-loop simulations, even when there are up to 15 interacting joints to be controlled. PMID:26696820

  8. Closed-Loop Neuromorphic Benchmarks.

    PubMed

    Stewart, Terrence C; DeWolf, Travis; Kleinhans, Ashley; Eliasmith, Chris

    2015-01-01

    Evaluating the effectiveness and performance of neuromorphic hardware is difficult. It is even more difficult when the task of interest is a closed-loop task; that is, a task where the output from the neuromorphic hardware affects some environment, which then in turn affects the hardware's future input. However, closed-loop situations are one of the primary potential uses of neuromorphic hardware. To address this, we present a methodology for generating closed-loop benchmarks that makes use of a hybrid of real physical embodiment and a type of "minimal" simulation. Minimal simulation has been shown to lead to robust real-world performance, while still maintaining the practical advantages of simulation, such as making it easy for the same benchmark to be used by many researchers. This method is flexible enough to allow researchers to explicitly modify the benchmarks to identify specific task domains where particular hardware excels. To demonstrate the method, we present a set of novel benchmarks that focus on motor control for an arbitrary system with unknown external forces. Using these benchmarks, we show that an error-driven learning rule can consistently improve motor control performance across a randomly generated family of closed-loop simulations, even when there are up to 15 interacting joints to be controlled. PMID:26696820

  9. Closing the Loop with Exercises

    ERIC Educational Resources Information Center

    Altizer, Andy

    2008-01-01

    Conducting exercises provides a critical bridge between the theory of an Emergency Action Plan and its effective implementation. When conducted properly, exercises can fill the gap between training and after-action review to close the preparedness loop--before an actual emergency occurs. Often exercises are planned and conducted on campus based on…

  10. Bimodal loop-gap resonator

    NASA Astrophysics Data System (ADS)

    Piasecki, W.; Froncisz, W.; Hyde, James S.

    1996-05-01

    A bimodal loop-gap resonator for use in electron paramagnetic resonance (EPR) spectroscopy at S band is described. It consists of two identical one-loop-one-gap resonators in coaxial juxtaposition. In one mode, the currents in the two loops are parallel and in the other antiparallel. By introducing additional capacitors between the loops, the frequencies of the two modes can be made to coincide. Details are given concerning variable coupling to each mode, tuning of the resonant frequency of one mode to that of the other, and adjustment of the isolation between modes. An equivalent circuit is given and network analysis carried out both experimentally and theoretically. EPR applications are described including (a) probing of the field distributions with DPPH, (b) continuous wave (cw) EPR with a spin-label line sample, (c) cw electron-electron double resonance (ELDOR), (d) modulation of saturation, and (e) saturation-recovery (SR) EPR. Bloch induction experiments can be performed when the sample extends half way through the structure, but microwave signals induced by Mx and My components of magnetization cancel when it extends completely through. This latter situation is particularly favorable for SR, modulation of saturation, and ELDOR experiments, which depend on observing Mz indirectly using a second weak observing microwave source.

  11. DEEPER BY THE DOZEN: UNDERSTANDING THE CROSS-FIELD TEMPERATURE DISTRIBUTIONS OF CORONAL LOOPS

    SciTech Connect

    Schmelz, J. T.; Pathak, S.; Jenkins, B. S.; Worley, B. T.

    2013-02-10

    Spectroscopic analysis of coronal loops has revealed a variety of cross-field temperature distributions. Some loops appear to be isothermal while others require multithermal plasma. The EUV Imaging Spectrometer on Hinode has the spatial resolution and temperature coverage required for differential emission measure (DEM) analysis of coronal loops. Our results also use data from the X-Ray Telescope on Hinode as a high-temperature constraint. Of our 12 loops, two were post-flare loops with broad temperature distributions, two were narrow but not quite isothermal, and the remaining eight were in the mid range. We consider our DEM methods to be a significant advance over previous work, and it is also reassuring to learn that our findings are consistent with results available in the literature. For the quiescent loops analyzed here, 10 MK plasma, a signature of nanoflares, appears to be absent at a level of approximately two orders of magnitude down from the DEM peak. We find some evidence that warmer loops require broader DEMs. The cross-field temperatures obtained here cannot be modeled as single flux tubes. Rather, the observed loop must be composed of several or many unresolved strands. The plasma contained in each of these strands could be cooling at different rates, contributing to the multithermal nature of the observed loop pixels. An important implication of our DEM results involves observations from future instruments. Once solar telescopes can truly resolve X-ray and EUV coronal structures, these images would have to reveal the loop substructure implied by our multithermal results.

  12. Unresolved Fine-scale Structure in Solar Coronal Loop-tops

    NASA Astrophysics Data System (ADS)

    Scullion, E.; Rouppe van der Voort, L.; Wedemeyer, S.; Antolin, P.

    2014-12-01

    New and advanced space-based observing facilities continue to lower the resolution limit and detect solar coronal loops in greater detail. We continue to discover even finer substructures within coronal loop cross-sections, in order to understand the nature of the solar corona. Here, we push this lower limit further to search for the finest coronal loop substructures, through taking advantage of the resolving power of the Swedish 1 m Solar Telescope/CRisp Imaging Spectro-Polarimeter (CRISP), together with co-observations from the Solar Dynamics Observatory/Atmospheric Image Assembly (AIA). High-resolution imaging of the chromospheric Hα 656.28 nm spectral line core and wings can, under certain circumstances, allow one to deduce the topology of the local magnetic environment of the solar atmosphere where its observed. Here, we study post-flare coronal loops, which become filled with evaporated chromosphere that rapidly condenses into chromospheric clumps of plasma (detectable in Hα) known as a coronal rain, to investigate their fine-scale structure. We identify, through analysis of three data sets, large-scale catastrophic cooling in coronal loop-tops and the existence of multi-thermal, multi-stranded substructures. Many cool strands even extend fully intact from loop-top to footpoint. We discover that coronal loop fine-scale strands can appear bunched with as many as eight parallel strands within an AIA coronal loop cross-section. The strand number density versus cross-sectional width distribution, as detected by CRISP within AIA-defined coronal loops, most likely peaks at well below 100 km, and currently, 69% of the substructure strands are statistically unresolved in AIA coronal loops.

  13. Unresolved fine-scale structure in solar coronal loop-tops

    SciTech Connect

    Scullion, E.; Van der Voort, L. Rouppe; Wedemeyer, S.; Antolin, P.

    2014-12-10

    New and advanced space-based observing facilities continue to lower the resolution limit and detect solar coronal loops in greater detail. We continue to discover even finer substructures within coronal loop cross-sections, in order to understand the nature of the solar corona. Here, we push this lower limit further to search for the finest coronal loop substructures, through taking advantage of the resolving power of the Swedish 1 m Solar Telescope/CRisp Imaging Spectro-Polarimeter (CRISP), together with co-observations from the Solar Dynamics Observatory/Atmospheric Image Assembly (AIA). High-resolution imaging of the chromospheric Hα 656.28 nm spectral line core and wings can, under certain circumstances, allow one to deduce the topology of the local magnetic environment of the solar atmosphere where its observed. Here, we study post-flare coronal loops, which become filled with evaporated chromosphere that rapidly condenses into chromospheric clumps of plasma (detectable in Hα) known as a coronal rain, to investigate their fine-scale structure. We identify, through analysis of three data sets, large-scale catastrophic cooling in coronal loop-tops and the existence of multi-thermal, multi-stranded substructures. Many cool strands even extend fully intact from loop-top to footpoint. We discover that coronal loop fine-scale strands can appear bunched with as many as eight parallel strands within an AIA coronal loop cross-section. The strand number density versus cross-sectional width distribution, as detected by CRISP within AIA-defined coronal loops, most likely peaks at well below 100 km, and currently, 69% of the substructure strands are statistically unresolved in AIA coronal loops.

  14. Inherent directionality explains the lack of feedback loops in empirical networks

    PubMed Central

    Domínguez-García, Virginia; Pigolotti, Simone; Muñoz, Miguel A.

    2014-01-01

    We explore the hypothesis that the relative abundance of feedback loops in many empirical complex networks is severely reduced owing to the presence of an inherent global directionality. Aimed at quantifying this idea, we propose a simple probabilistic model in which a free parameter γ controls the degree of inherent directionality. Upon strengthening such directionality, the model predicts a drastic reduction in the fraction of loops which are also feedback loops. To test this prediction, we extensively enumerated loops and feedback loops in many empirical biological, ecological and socio-technological directed networks. We show that, in almost all cases, empirical networks have a much smaller fraction of feedback loops than network randomizations. Quite remarkably, this empirical finding is quantitatively reproduced, for all loop lengths, by our model by fitting its only parameter γ. Moreover, the fitted value of γ correlates quite well with another direct measurement of network directionality, performed by means of a novel algorithm. We conclude that the existence of an inherent network directionality provides a parsimonious quantitative explanation for the observed lack of feedback loops in empirical networks. PMID:25531727

  15. Inherent directionality explains the lack of feedback loops in empirical networks.

    PubMed

    Domínguez-García, Virginia; Pigolotti, Simone; Muñoz, Miguel A

    2014-01-01

    We explore the hypothesis that the relative abundance of feedback loops in many empirical complex networks is severely reduced owing to the presence of an inherent global directionality. Aimed at quantifying this idea, we propose a simple probabilistic model in which a free parameter γ controls the degree of inherent directionality. Upon strengthening such directionality, the model predicts a drastic reduction in the fraction of loops which are also feedback loops. To test this prediction, we extensively enumerated loops and feedback loops in many empirical biological, ecological and socio-technological directed networks. We show that, in almost all cases, empirical networks have a much smaller fraction of feedback loops than network randomizations. Quite remarkably, this empirical finding is quantitatively reproduced, for all loop lengths, by our model by fitting its only parameter γ. Moreover, the fitted value of γ correlates quite well with another direct measurement of network directionality, performed by means of a novel algorithm. We conclude that the existence of an inherent network directionality provides a parsimonious quantitative explanation for the observed lack of feedback loops in empirical networks. PMID:25531727

  16. Spatially Resolved Mapping of Disorder Type and Distribution in Random Systems using Artificial Neural Network Recognition

    SciTech Connect

    Jesse, Stephen; Kalinin, Sergei V; Kumar, Amit; Ovchinnikov, Oleg S; Guo, Senli; Griggio, Flavio; Trolier-Mckinstry, Susan E

    2011-01-01

    The spatial variability of the polarization dynamics in thin film ferroelectric capacitors was probed by recognition analysis of spatially-resolved spectroscopic data. Switching spectroscopy piezoresponse force microscopy was used to measure local hysteresis loops and map them on a 2D random-bond, random-field Ising model. A neural-network based recognition approach was utilized to analyze the hysteresis loops and their spatial variability. Strong variability is observed in the polarization dynamics around macroscopic cracks due to the modified local elastic and electric boundary conditions, with most pronounced effect on the length scale of ~100 nm away from the crack.

  17. Clustering of Hadronic Showers with a Structural Algorithm

    SciTech Connect

    Charles, M.J.; /SLAC

    2005-12-13

    The internal structure of hadronic showers can be resolved in a high-granularity calorimeter. This structure is described in terms of simple components and an algorithm for reconstruction of hadronic clusters using these components is presented. Results from applying this algorithm to simulated hadronic Z-pole events in the SiD concept are discussed.

  18. Loop Closing Detection in RGB-D SLAM Combining Appearance and Geometric Constraints.

    PubMed

    Zhang, Heng; Liu, Yanli; Tan, Jindong

    2015-01-01

    A kind of multi feature points matching algorithm fusing local geometric constraints is proposed for the purpose of quickly loop closing detection in RGB-D Simultaneous Localization and Mapping (SLAM). The visual feature is encoded with BRAND (binary robust appearance and normals descriptor), which efficiently combines appearance and geometric shape information from RGB-D images. Furthermore, the feature descriptors are stored using the Locality-Sensitive-Hashing (LSH) technique and hierarchical clustering trees are used to search for these binary features. Finally, the algorithm for matching of multi feature points using local geometric constraints is provided, which can effectively reject the possible false closure hypotheses. We demonstrate the efficiency of our algorithms by real-time RGB-D SLAM with loop closing detection in indoor image sequences taken with a handheld Kinect camera and comparative experiments using other algorithms in RTAB-Map dealing with a benchmark dataset. PMID:26102492

  19. Loop Closing Detection in RGB-D SLAM Combining Appearance and Geometric Constraints

    PubMed Central

    Zhang, Heng; Liu, Yanli; Tan, Jindong

    2015-01-01

    A kind of multi feature points matching algorithm fusing local geometric constraints is proposed for the purpose of quickly loop closing detection in RGB-D Simultaneous Localization and Mapping (SLAM). The visual feature is encoded with BRAND (binary robust appearance and normals descriptor), which efficiently combines appearance and geometric shape information from RGB-D images. Furthermore, the feature descriptors are stored using the Locality-Sensitive-Hashing (LSH) technique and hierarchical clustering trees are used to search for these binary features. Finally, the algorithm for matching of multi feature points using local geometric constraints is provided, which can effectively reject the possible false closure hypotheses. We demonstrate the efficiency of our algorithms by real-time RGB-D SLAM with loop closing detection in indoor image sequences taken with a handheld Kinect camera and comparative experiments using other algorithms in RTAB-Map dealing with a benchmark dataset. PMID:26102492

  20. Open-loop and closed-loop control of dissociative ionization of ethanol in intense laser fields

    SciTech Connect

    Yazawa, Hiroki; Tanabe, Takasumi; Okamoto, Tatsuyoshi; Yamanaka, Mio; Kannari, Fumihiko; Itakura, Ryuji; Yamanouchi, Kaoru

    2006-05-28

    The relative yield of the C-O bond breaking with respect to the C-C bond breaking in ethanol cation C{sub 2}H{sub 5}OH{sup +} is maximized in intense laser fields (10{sup 13}-10{sup 15} W/cm{sup 2}) by open-loop and closed-loop optimization procedures. In the open-loop optimization, a train of intense laser pulses are synthesized so that the temporal separation between the first and last pulses becomes 800 fs, and the number and width of the pulses within a train are systematically varied. When the duration of 800 fs is filled with laser fields by increasing the number of pulses or by stretching all pulses in a triple pulse train, the relative yield of the C-O bond breaking becomes significantly large. In the closed-loop optimization using a self-learning algorithm, the four dispersion coefficients or the phases of 128 frequency components of an intense laser pulse are adopted as optimized parameters. From these optimization experiments it is revealed that the yield ratio of the C-O bond breaking is maximized as far as the total duration of the intense laser field reaches as long as {approx}1 ps and that the intermittent disappearance of the laser field within a pulse does not affect the relative yields of the bond breaking pathways.

  1. Exotic singularities and spatially curved loop quantum cosmology

    SciTech Connect

    Singh, Parampreet; Vidotto, Francesca

    2011-03-15

    We investigate the occurrence of various exotic spacelike singularities in the past and the future evolution of k={+-}1 Friedmann-Robertson-Walker model and loop quantum cosmology using a sufficiently general phenomenological model for the equation of state. We highlight the nontrivial role played by the intrinsic curvature for these singularities and the new physics which emerges at the Planck scale. We show that quantum gravity effects generically resolve all strong curvature singularities including big rip and big freeze singularities. The weak singularities, which include sudden and big brake singularities, are ignored by quantum gravity when spatial curvature is negative, as was previously found for the spatially flat model. Interestingly, for the spatially closed model there exist cases where weak singularities may be resolved when they occur in the past evolution. The spatially closed model exhibits another novel feature. For a particular class of equation of state, this model also exhibits an additional physical branch in loop quantum cosmology, a baby universe separated from the parent branch. Our analysis generalizes previous results obtained on the resolution of strong curvature singularities in flat models to isotropic spacetimes with nonzero spatial curvature.

  2. Lac Repressor Mediated DNA Looping: Monte Carlo Simulation of Constrained DNA Molecules Complemented with Current Experimental Results

    PubMed Central

    Biton, Yoav Y.; Kumar, Sandip; Dunlap, David; Swigon, David

    2014-01-01

    Tethered particle motion (TPM) experiments can be used to detect time-resolved loop formation in a single DNA molecule by measuring changes in the length of a DNA tether. Interpretation of such experiments is greatly aided by computer simulations of DNA looping which allow one to analyze the structure of the looped DNA and estimate DNA-protein binding constants specific for the loop formation process. We here present a new Monte Carlo scheme for accurate simulation of DNA configurations subject to geometric constraints and apply this method to Lac repressor mediated DNA looping, comparing the simulation results with new experimental data obtained by the TPM technique. Our simulations, taking into account the details of attachment of DNA ends and fluctuations of the looped subsegment of the DNA, reveal the origin of the double-peaked distribution of RMS values observed by TPM experiments by showing that the average RMS value for anti-parallel loop types is smaller than that of parallel loop types. The simulations also reveal that the looping probabilities for the anti-parallel loop types are significantly higher than those of the parallel loop types, even for loops of length 600 and 900 base pairs, and that the correct proportion between the heights of the peaks in the distribution can only be attained when loops with flexible Lac repressor conformation are taken into account. Comparison of the in silico and in vitro results yields estimates for the dissociation constants characterizing the binding affinity between O1 and Oid DNA operators and the dimeric arms of the Lac repressor. PMID:24800809

  3. Anaphora Resolution Algorithm for Sanskrit

    NASA Astrophysics Data System (ADS)

    Pralayankar, Pravin; Devi, Sobha Lalitha

    This paper presents an algorithm, which identifies different types of pronominal and its antecedents in Sanskrit, an Indo-European language. The computational grammar implemented here uses very familiar concepts such as clause, subject, object etc., which are identified with the help of morphological information and concepts such as precede and follow. It is well known that natural languages contain anaphoric expressions, gaps and elliptical constructions of various kinds and that understanding of natural languages involves assignment of interpretations to these elements. Therefore, it is only to be expected that natural language understanding systems must have the necessary mechanism to resolve the same. The method we adopt here for resolving the anaphors is by exploiting the morphological richness of the language. The system is giving encouraging results when tested with a small corpus.

  4. Deconvolution method for recovering the photon time-of-flight distribution from time-resolved measurements.

    PubMed

    Diop, Mamadou; St Lawrence, Keith

    2012-06-15

    A nonparametric deconvolution algorithm for recovering the photon time-of-flight distribution (TOFD) from time-resolved (TR) measurements is described. The algorithm combines wavelet denoising and a two-stage deconvolution method based on generalized singular value decomposition and Tikhonov regularization. The efficacy of the algorithm was tested on simulated and experimental TR data and the results show that it can recover the photon TOFD with high fidelity. Combined with the microscopic Beer-Lambert law, the algorithm enables accurate quantification of absorption changes from arbitrary time-of-flight windows, thereby optimizing the depth sensitivity provided by TR measurements. PMID:22739907

  5. A translational platform for prototyping closed-loop neuromodulation systems

    PubMed Central

    Afshar, Pedram; Khambhati, Ankit; Stanslaski, Scott; Carlson, David; Jensen, Randy; Linde, Dave; Dani, Siddharth; Lazarewicz, Maciej; Cong, Peng; Giftakis, Jon; Stypulkowski, Paul; Denison, Tim

    2013-01-01

    While modulating neural activity through stimulation is an effective treatment for neurological diseases such as Parkinson's disease and essential tremor, an opportunity for improving neuromodulation therapy remains in automatically adjusting therapy to continuously optimize patient outcomes. Practical issues associated with achieving this include the paucity of human data related to disease states, poorly validated estimators of patient state, and unknown dynamic mappings of optimal stimulation parameters based on estimated states. To overcome these challenges, we present an investigational platform including: an implanted sensing and stimulation device to collect data and run automated closed-loop algorithms; an external tool to prototype classifier and control-policy algorithms; and real-time telemetry to update the implanted device firmware and monitor its state. The prototyping system was demonstrated in a chronic large animal model studying hippocampal dynamics. We used the platform to find biomarkers of the observed states and transfer functions of different stimulation amplitudes. Data showed that moderate levels of stimulation suppress hippocampal beta activity, while high levels of stimulation produce seizure-like after-discharge activity. The biomarker and transfer function observations were mapped into classifier and control-policy algorithms, which were downloaded to the implanted device to continuously titrate stimulation amplitude for the desired network effect. The platform is designed to be a flexible prototyping tool and could be used to develop improved mechanistic models and automated closed-loop systems for a variety of neurological disorders. PMID:23346048

  6. One-loop kink mass shifts: A computational approach

    NASA Astrophysics Data System (ADS)

    Alonso Izquierdo, A.; Guilarte, J. Mateos

    2011-11-01

    In this paper we develop a procedure to compute the one-loop quantum correction to the kink masses in generic (1+1)-dimensional one-component scalar field theoretical models. The procedure uses the generalized zeta function regularization method helped by the Gilkey-de Witt asymptotic expansion of the heat function via Mellin's transform. We find a formula for the one-loop kink mass shift that depends only on the part of the energy density with no field derivatives, evaluated by means of a symbolic software algorithm that automates the computation. The improved algorithm with respect to earlier work in this subject has been tested in the sine-Gordon and λ(ϕ)24 models. The quantum corrections of the sG-soliton and λ(-kink masses have been estimated with a relative error of 0.00006% and 0.00007% respectively. Thereafter, the algorithm is applied to other models. In particular, an interesting one-parametric family of double sine-Gordon models interpolating between the ordinary sine-Gordon and a re-scaled sine-Gordon model is addressed. Another one-parametric family, in this case of ϕ models, is analyzed. The main virtue of our procedure is its versatility: it can be applied to practically any type of relativistic scalar field models supporting kinks.

  7. Evolution in a Braided Loop Ensemble

    NASA Video Gallery

    This braided loop has several loops near the 'base' that appear to be unwinding with significant apparent outflow. This is evidence of untwisting, and the braided structure also seeming to unwind w...

  8. Approaches to resolving trade disputes.

    PubMed

    Wilson, D W; Thiermann, A B

    2003-08-01

    The authors discuss the various approaches to resolving trade disputes available to Member Countries of the OIE (World organisation for animal health). The paper first describes the rights and obligations of Member Countries in setting health measures for the importation of animals and animal products, according to the provisions of the World Trade Organization (WTO) Agreement on the Application of Sanitary and Phytosanitary Measures (the SPS Agreement). The authors indicate how OIE standards may be used to set import measures and introduce issues such as equivalence and the use of provisional measures, which are both areas of potential conflict. The authors then describe the options available for resolving disputes--bilateral discussions, mediation through the OIE, the use of the WTO SPS Committee and the formal WTO dispute settlement process, discussing the advantages and disadvantages of each. PMID:15884603

  9. Fragmentation of cosmic-string loops

    NASA Technical Reports Server (NTRS)

    York, Thomas

    1989-01-01

    The fragmentation of cosmic string loops is discussed, and the results of a simulation of this process are presented. The simulation can evolve any of a large class of loops essentially exactly, including allowing fragments that collide to join together. Such reconnection enhances the production of small fragments, but not drastically. With or without reconnections, the fragmentation process produces a collection of nonself-intersecting loops whose typical length is on the order of the persistence length of the initial loop.

  10. Time-resolved molecular imaging

    NASA Astrophysics Data System (ADS)

    Xu, Junliang; Blaga, Cosmin I.; Agostini, Pierre; DiMauro, Louis F.

    2016-06-01

    Time-resolved molecular imaging is a frontier of ultrafast optical science and physical chemistry. In this article, we review present and future key spectroscopic and microscopic techniques for ultrafast imaging of molecular dynamics and show their differences and connections. The advent of femtosecond lasers and free electron x-ray lasers bring us closer to this goal, which eventually will extend our knowledge about molecular dynamics to the attosecond time domain.

  11. STED microscopy resolves nanoparticle assemblies

    NASA Astrophysics Data System (ADS)

    Willig, K. I.; Keller, J.; Bossi, M.; Hell, S. W.

    2006-06-01

    We demonstrate the ability of stimulated emission depletion (STED) microscopy, a far-field fluorescence imaging technique with diffraction-unlimited resolution, to reveal the spatial order of fluorescent nanoparticles. Unlike its confocal counterpart, here STED microscopy resolves the arrangements of densely packed 40 nm beads, supramolecular aggregates in a cell membrane, and colloidal nanoparticles. Both raw and linearly deconvolved data disclose unprecedented details of both biological and non-biological nanopatterns.

  12. Resolved Observations of Transition Disks

    NASA Astrophysics Data System (ADS)

    Casassus, Simon

    2016-04-01

    Resolved observations are bringing new constraints on the origin of radial gaps in protoplanetary disks. The kinematics, sampled in detail in one case-study, are indicative of non-Keplerian flows, corresponding to warped structures and accretion which may both play a role in the development of cavities. Disk asymmetries seen in the radio continuum are being interpreted in the context of dust segregation via aerodynamic trapping. We summarise recent observational progress, and describe prospects for improvements in the near term.

  13. NONLINEAR FORCE-FREE MAGNETIC FIELD FITTING TO CORONAL LOOPS WITH AND WITHOUT STEREOSCOPY

    SciTech Connect

    Aschwanden, Markus J.

    2013-02-15

    We developed a new nonlinear force-free magnetic field (NLFFF) forward-fitting algorithm based on an analytical approximation of force-free and divergence-free NLFFF solutions, which requires as input a line-of-sight magnetogram and traced two-dimensional (2D) loop coordinates of coronal loops only, in contrast to stereoscopically triangulated three-dimensional loop coordinates used in previous studies. Test results of simulated magnetic configurations and from four active regions observed with STEREO demonstrate that NLFFF solutions can be fitted with equal accuracy with or without stereoscopy, which relinquishes the necessity of STEREO data for magnetic modeling of active regions (on the solar disk). The 2D loop tracing method achieves a 2D misalignment of {mu}{sub 2} = 2. Degree-Sign 7 {+-} 1. Degree-Sign 3 between the model field lines and observed loops, and an accuracy of Almost-Equal-To 1.0% for the magnetic energy or free magnetic energy ratio. The three times higher spatial resolution of TRACE or SDO/AIA (compared with STEREO) also yields a proportionally smaller misalignment angle between model fit and observations. Visual/manual loop tracings are found to produce more accurate magnetic model fits than automated tracing algorithms. The computation time of the new forward-fitting code amounts to a few minutes per active region.

  14. Nonlinear Force-free Magnetic Field Fitting to Coronal Loops with and without Stereoscopy

    NASA Astrophysics Data System (ADS)

    Aschwanden, Markus J.

    2013-02-01

    We developed a new nonlinear force-free magnetic field (NLFFF) forward-fitting algorithm based on an analytical approximation of force-free and divergence-free NLFFF solutions, which requires as input a line-of-sight magnetogram and traced two-dimensional (2D) loop coordinates of coronal loops only, in contrast to stereoscopically triangulated three-dimensional loop coordinates used in previous studies. Test results of simulated magnetic configurations and from four active regions observed with STEREO demonstrate that NLFFF solutions can be fitted with equal accuracy with or without stereoscopy, which relinquishes the necessity of STEREO data for magnetic modeling of active regions (on the solar disk). The 2D loop tracing method achieves a 2D misalignment of μ2 = 2.°7 ± 1.°3 between the model field lines and observed loops, and an accuracy of ≈1.0% for the magnetic energy or free magnetic energy ratio. The three times higher spatial resolution of TRACE or SDO/AIA (compared with STEREO) also yields a proportionally smaller misalignment angle between model fit and observations. Visual/manual loop tracings are found to produce more accurate magnetic model fits than automated tracing algorithms. The computation time of the new forward-fitting code amounts to a few minutes per active region.

  15. Chromosome Compaction by Active Loop Extrusion.

    PubMed

    Goloborodko, Anton; Marko, John F; Mirny, Leonid A

    2016-05-24

    During cell division, chromosomes are compacted in length by more than a 100-fold. A wide range of experiments demonstrated that in their compacted state, mammalian chromosomes form arrays of closely stacked consecutive ∼100 kb loops. The mechanism underlying the active process of chromosome compaction into a stack of loops is unknown. Here we test the hypothesis that chromosomes are compacted by enzymatic machines that actively extrude chromatin loops. When such loop-extruding factors (LEF) bind to chromosomes, they progressively bridge sites that are further away along the chromosome, thus extruding a loop. We demonstrate that collective action of LEFs leads to formation of a dynamic array of consecutive loops. Simulations and an analytically solved model identify two distinct steady states: a sparse state, where loops are highly dynamic but provide little compaction; and a dense state, where there are more stable loops and dramatic chromosome compaction. We find that human chromosomes operate at the border of the dense steady state. Our analysis also shows how the macroscopic characteristics of the loop array are determined by the microscopic properties of LEFs and their abundance. When the number of LEFs are used that match experimentally based estimates, the model can quantitatively reproduce the average loop length, the degree of compaction, and the general loop-array morphology of compact human chromosomes. Our study demonstrates that efficient chromosome compaction can be achieved solely by an active loop-extrusion process. PMID:27224481

  16. Hard thermal loops in static external fields

    SciTech Connect

    Frenkel, J.; Takahashi, N.; Pereira, S. H.

    2009-04-15

    We examine, in the imaginary-time formalism, the high temperature behavior of n-point thermal loops in static Yang-Mills and gravitational fields. We show that in this regime, any hard thermal loop gives the same leading contribution as the one obtained by evaluating the loop integral at zero external energies and momenta.

  17. Interference Lattice-based Loop Nest Tilings for Stencil Computations

    NASA Technical Reports Server (NTRS)

    VanderWijngaart, Rob F.; Frumkin, Michael

    2000-01-01

    adjacent tiles are visited successively, there will be no replacement misses on the shared boundary. The iteration space may be covered with pencils larger than the size of the cache while avoiding data conflicts if the pencils are traversed by a scanning-face method. Replacement misses are incurred only on the boundaries of the pencils, and the number of misses is minimized by maximizing the volume of the scanning face, not the volume of the tile. We present an algorithm for constructing the most efficient scanning face for a given grid and stencil operator. In two dimensions it is based on a continued fraction algorithm. In three dimensions it follows Voronoi's successive minima algorithm. We show experimental results of using the scanning face, and compare with canonical loop orderings.

  18. Microgyroscope with closed loop output

    NASA Technical Reports Server (NTRS)

    Challoner, A. Dorian (Inventor); Gutierrez, Roman C. (Inventor); Tang, Tony K. (Inventor); Cargille, Donald R. (Inventor)

    2002-01-01

    A micro-gyroscope (10) having closed loop operation by a control voltage (V.sub.TY), that is demodulated by an output signal of the sense electrodes (S1, S2), providing Coriolis torque rebalance to prevent displacement of the micro-gyroscope (10) on the output axis (y-axis). The present invention provides wide-band, closed-loop operation for a micro-gyroscope (10) and allows the drive frequency to be closely tuned to a high Q sense axis resonance. A differential sense signal (S1-S2) is compensated and fed back by differentially changing the voltage on the drive electrodes to rebalance Coriolis torque. The feedback signal is demodulated in phase with the drive axis signal (K.sub..omega..crclbar..sub.x) to produce a measure of the Coriolis force.

  19. Loop connectors in dentogenic diastema.

    PubMed

    Nayar, Sanjna; Jayesh, Raghevendra; Venkateshwaran; Dinakarsamy, V

    2015-04-01

    Patients with a missing tooth along with diastema have limited treatment options to restore the edentulous space. The use of a conventional fixed partial denture (FPD) to replace the missing tooth may result in too wide anterior teeth leading to poor esthetics. Loss of anterior teeth with existing diastema may result in excess space available for pontic. This condition presents great esthetic challenge for prosthodontist. If implant supported prosthesis is not possible because of inadequate bone support, FPD along with loop connector may be a treatment option to maintain the diastema and provide optimal esthetic restoration. Here, we report a clinical case where FPD along with loop connector was used to achieve esthetic rehabilitation in maxillary anterior region in which midline diastema has been maintained. PMID:26015732

  20. Two Loop Higgs Unitarity Constraints

    NASA Astrophysics Data System (ADS)

    Maher, Peter Noel

    The perturbative approximation in the Symmetry Breaking sector of the Standard Model is investigated to two loops. The breakdown of perturbative unitarity seen at one loop is only slightly postponed. Attention is restricted to the coupled elastic scattering matrix of the neutral channels W^+W ^-, ZZ, HH, ZH. The high energy limit s gg M_sp{H} {2} gg M_sp{W}{2} and the Equivalence Theorem are used to simplify the calculation. The theory is renormalized on mass shell, in a way that automatically sums the tadpole graphs. Calculation of the counterterms was the most difficult part of the entire work. The running coupling and anomalous dimensions are calculated. The Landau pole of the running coupling is not significantly affected by the two loop contributions unless the coupling is large. Similarly, the anomalous dimensions are small. The eigen-amplitudes of the partial wave projected scattering matrix are analysed for breakdown of perturbative unitarity using Argand diagrams, and for term-wise convergence. It is found that if the Standard Model is to hold true up to sqrt{s} ~ 2TeV, the theory is strongly coupled and perturbative approximations are no longer trustworthy if M_{H} _sp{~}{>} 350 - 450 GeV. If the Standard Model is embedded in a perturbative grand unified theory, and assumed to hold true up to sqrt{s} = 10^ {15} GeV, then the Higgs mass is bounded M_{H} _sp{~ }{<} 160 GeV.

  1. Polyhedra in loop quantum gravity

    SciTech Connect

    Bianchi, Eugenio; Speziale, Simone; Dona, Pietro

    2011-02-15

    Intertwiners are the building blocks of spin-network states. The space of intertwiners is the quantization of a classical symplectic manifold introduced by Kapovich and Millson. Here we show that a theorem by Minkowski allows us to interpret generic configurations in this space as bounded convex polyhedra in R{sup 3}: A polyhedron is uniquely described by the areas and normals to its faces. We provide a reconstruction of the geometry of the polyhedron: We give formulas for the edge lengths, the volume, and the adjacency of its faces. At the quantum level, this correspondence allows us to identify an intertwiner with the state of a quantum polyhedron, thus generalizing the notion of the quantum tetrahedron familiar in the loop quantum gravity literature. Moreover, coherent intertwiners result to be peaked on the classical geometry of polyhedra. We discuss the relevance of this result for loop quantum gravity. In particular, coherent spin-network states with nodes of arbitrary valence represent a collection of semiclassical polyhedra. Furthermore, we introduce an operator that measures the volume of a quantum polyhedron and examine its relation with the standard volume operator of loop quantum gravity. We also comment on the semiclassical limit of spin foams with nonsimplicial graphs.

  2. Two-loop quantum gravity

    NASA Astrophysics Data System (ADS)

    van de Ven, Anton E. M.

    1992-07-01

    We prove the existence of a nonrenormalizable infinity in the two-loop effective action of perturbative quantum gravity by means of an explicit calculation. Our final result agrees with that obtained by earlier authors. We use the background-field method in coordinate space, combined with dimensional regularization and a heat kernel representation for the propagators. General covariance is manifestly preserved. Only vacuum graphs in the presence of an on-shell background metric need to be calculated. We extend the background covariant harmonic gauge to include terms nonlinear in the quantum gravitational fields and allow for general reparametrizations of those fields. For a particular gauge choice and field parametrization only two three-graviton and six four-graviton vertices are present in the action. Calculational labor is further reduced by restricting to backgrounds, which are not only Ricci-flat, but satisfy an additional constraint bilinear in the Weyl tensor. To handle the still formidable amount of algebra, we use the symbolic manipulation program FORM. We checked that the on-shell two-loop effective action is in fact independent of all gauge and field redefinition parameters. A two-loop analysis for Yang-Mills fields is included as well, since in that case we can give full details as well as simplify earlier analyses.

  3. Polyhedra in loop quantum gravity

    NASA Astrophysics Data System (ADS)

    Bianchi, Eugenio; Doná, Pietro; Speziale, Simone

    2011-02-01

    Intertwiners are the building blocks of spin-network states. The space of intertwiners is the quantization of a classical symplectic manifold introduced by Kapovich and Millson. Here we show that a theorem by Minkowski allows us to interpret generic configurations in this space as bounded convex polyhedra in R3: A polyhedron is uniquely described by the areas and normals to its faces. We provide a reconstruction of the geometry of the polyhedron: We give formulas for the edge lengths, the volume, and the adjacency of its faces. At the quantum level, this correspondence allows us to identify an intertwiner with the state of a quantum polyhedron, thus generalizing the notion of the quantum tetrahedron familiar in the loop quantum gravity literature. Moreover, coherent intertwiners result to be peaked on the classical geometry of polyhedra. We discuss the relevance of this result for loop quantum gravity. In particular, coherent spin-network states with nodes of arbitrary valence represent a collection of semiclassical polyhedra. Furthermore, we introduce an operator that measures the volume of a quantum polyhedron and examine its relation with the standard volume operator of loop quantum gravity. We also comment on the semiclassical limit of spin foams with nonsimplicial graphs.

  4. Quantum reduced loop gravity and the foundation of loop quantum cosmology

    NASA Astrophysics Data System (ADS)

    Alesci, Emanuele; Cianfrani, Francesco

    2016-06-01

    Quantum reduced loop gravity is a promising framework for linking loop quantum gravity and the effective semiclassical dynamics of loop quantum cosmology. We review its basic achievements and its main perspectives, outlining how it provides a quantum description of the Universe in terms of a cuboidal graph which constitutes the proper framework for applying loop techniques in a cosmological setting.

  5. Root Locus Algorithms for Programmable Pocket Calculators

    NASA Technical Reports Server (NTRS)

    Wechsler, E. R.

    1983-01-01

    Two algorithms are described which allow the plotting of individual points on a root locus diagram with or without time delay. The development was performed during the design of a continuous phase shifter used in the Baseband Antenna Combiner for the Deep Space Network (DSN). The algorithms, which are expected to be useful in similar DSN efforts, are simple enough to be implemented on a programmable pocket calculator. The coordinates of the open-loop zeros and poles, the gain constant K, and the time delay T are the data inputs.

  6. Spatially resolved mapping of disorder type and distribution in random systems using artificial neural network recognition

    NASA Astrophysics Data System (ADS)

    Kumar, A.; Ovchinnikov, O.; Guo, S.; Griggio, F.; Jesse, S.; Trolier-McKinstry, S.; Kalinin, S. V.

    2011-07-01

    The spatial variability of the polarization dynamics in thin film ferroelectric capacitors was probed by recognition analysis of spatially resolved spectroscopic data. Switching spectroscopy piezoresponse force microscopy (SSPFM) was used to measure local hysteresis loops and map them on a two dimensional (2D) random-bond, random-field Ising model. A neural-network based recognition approach was utilized to analyze the hysteresis loops and their spatial variability. Strong variability is observed in the polarization dynamics around macroscopic cracks because of the modified local-elastic and electric-boundary conditions, with the most pronounced effect on the length scale of ˜100 nm away from the crack. The recognition approach developed here is universal and can potentially be applied for arbitrary macroscopic and spatially resolved data, including temperature- and field-dependent hysteresis, I-V curve mapping, electron microscopy electron energy loss spectroscopy (EELS) imaging, and many others.

  7. Covariant effective action for loop quantum cosmology a la Palatini

    SciTech Connect

    Olmo, Gonzalo J.; Singh, Parampreet E-mail: psingh@perimeterinstitute.ca

    2009-01-15

    In loop quantum cosmology, non-perturbative quantum gravity effects lead to the resolution of the big bang singularity by a quantum bounce without introducing any new degrees of freedom. Though fundamentally discrete, the theory admits a continuum description in terms of an effective Hamiltonian. Here we provide an algorithm to obtain the corresponding effective action, establishing in this way the covariance of the theory for the first time. This result provides new insights on the continuum properties of the discrete structure of quantum geometry and opens new avenues to extract physical predictions such as those related to gauge invariant cosmological perturbations.

  8. The Human is the Loop: New Directions for Visual Analytics

    SciTech Connect

    Endert, Alexander; Hossain, Shahriar H.; Ramakrishnan, Naren; North, Chris; Fiaux, Patrick; Andrews, Christopher

    2014-01-28

    Visual analytics is the science of marrying interactive visualizations and analytic algorithms to support exploratory knowledge discovery in large datasets. We argue for a shift from a ‘human in the loop’ philosophy for visual analytics to a ‘human is the loop’ viewpoint, where the focus is on recognizing analysts’ work processes, and seamlessly fitting analytics into that existing interactive process. We survey a range of projects that provide visual analytic support contextually in the sensemaking loop, and outline a research agenda along with future challenges.

  9. A New Technique for Analysis of Static Eccentricity in Axial Flux Resolver

    NASA Astrophysics Data System (ADS)

    Tootoonchian, F.; Abbaszadeh, K.; Ardebili, M.

    2012-01-01

    Resolvers have been widely used in motion control systems as position sensors. This paper deals with the analysis of Axial Flux Resolvers. Axial flux resolvers are a group of resolvers which can be used in high performance servomechanisms. The accuracy of resolver detected position is affected by errors. Some of these errors are caused by speed fluctuations, permeance ripples, unbalanced voltages, and eccentricity between rotor and stator. Among these errors the static eccentricity > and Lq values and then, the static eccentricity effect based on the developed model is studied. A novel algorithm is proposed for suppressing the eccentricity error. This method is based on analytical model and modern control fundamentals. In a comparison, simulation and experimental results show good agreement. Finally, the effect of air gap length, pole number and excitation voltage on position error of eccentric AFR is investigated, practically.

  10. Resolving Conflicting Predictions from Multimapping Reads.

    PubMed

    Canzar, Stefan; Elbassioni, Khaled; Jones, Mitchell; Mestre, Julián

    2016-03-01

    The first step in the analysis of data produced by ultra-high-throughput next-generation sequencing technology is to map short sequence "reads" to a reference genome, if available. Sequencing errors, repeat regions, and polymorphisms may lead a read to align to multiple locations in the genome reasonably well. While ignoring such multimapping reads, or some of their alignments, will reduce the sensitivity of almost any type of downstream analysis (e.g., detecting structural variants), erroneous mappings will typically yield false positive predictions. Here we propose a framework that aims to identify true predictions among a large set of candidate predictions by selecting for each read a unique mapping that collectively imply conflict-free predictions. We formulate this problem as the maximum facility location problem, for which we propose LP-rounding heuristics. We provide a theoretic guarantee on the quality of the solution and demonstrate the utility of our algorithm in resolving conflicting deletions implied by simulated reads mapping ambiguously to Craig Venter's genome model and Illumina sequencing reads of the well-studied NA12878 individual. PMID:26745826

  11. Prediction of calcium-binding sites by combining loop-modeling with machine learning

    PubMed Central

    2009-01-01

    limited loop modeling (e.g. loops less than 17 residues) combined with pattern matching algorithms can recover functions and propose putative conformations associated with these functions. PMID:20003365

  12. Protein loop modeling using a new hybrid energy function and its application to modeling in inaccurate structural environments.

    PubMed

    Park, Hahnbeom; Lee, Gyu Rie; Heo, Lim; Seok, Chaok

    2014-01-01

    Protein loop modeling is a tool for predicting protein local structures of particular interest, providing opportunities for applications involving protein structure prediction and de novo protein design. Until recently, the majority of loop modeling methods have been developed and tested by reconstructing loops in frameworks of experimentally resolved structures. In many practical applications, however, the protein loops to be modeled are located in inaccurate structural environments. These include loops in model structures, low-resolution experimental structures, or experimental structures of different functional forms. Accordingly, discrepancies in the accuracy of the structural environment assumed in development of the method and that in practical applications present additional challenges to modern loop modeling methods. This study demonstrates a new strategy for employing a hybrid energy function combining physics-based and knowledge-based components to help tackle this challenge. The hybrid energy function is designed to combine the strengths of each energy component, simultaneously maintaining accurate loop structure prediction in a high-resolution framework structure and tolerating minor environmental errors in low-resolution structures. A loop modeling method based on global optimization of this new energy function is tested on loop targets situated in different levels of environmental errors, ranging from experimental structures to structures perturbed in backbone as well as side chains and template-based model structures. The new method performs comparably to force field-based approaches in loop reconstruction in crystal structures and better in loop prediction in inaccurate framework structures. This result suggests that higher-accuracy predictions would be possible for a broader range of applications. The web server for this method is available at http://galaxy.seoklab.org/loop with the PS2 option for the scoring function. PMID:25419655

  13. Premeasured Chordal Loops for Mitral Valve Repair.

    PubMed

    Gillinov, Marc; Quinn, Reed; Kerendi, Faraz; Gaudiani, Vince; Shemin, Richard; Barnhart, Glenn; Raines, Edward; Gerdisch, Marc W; Banbury, Michael

    2016-09-01

    Premeasured expanded polytetrafluoroethylene chordal loops with integrated sutures for attachment to the papillary muscle and leaflet edges facilitate correction of mitral valve prolapse. Configured as a group of 3 loops (length range 12 to 24 mm), the loops are attached to a pledget that is passed through the papillary muscle and tied. Each of the loops has 2 sutures with attached needles; these needles are passed through the free edge of the leaflet and then the sutures are tied to each other, securing the chordal loop to the leaflet. PMID:27549563

  14. Z-Sum approach to loop integrals

    NASA Astrophysics Data System (ADS)

    Rottmann, Paulo A.

    We study the applicability of the Z-Sum approach to multi-loop calculations with massive particles in perturbative quantum field theory. We systematically analyze the case of one-loop scalar integrals, which represent the building blocks of any higher-loop calculation. We focus in particular on triangle one-loop integrals and identify strengths and limitations of the Z-Sum approach, extending our results to the case of one-loop box integrals when appropriate. We conclude with the calculation of a specific physical example: the calculation of heavy flavor corrections to the renormalized scattering amplitude for deep inelastic scattering.

  15. Dynamic Aperture-based Solar Loop Segmentation

    NASA Technical Reports Server (NTRS)

    Lee, Jon Kwan; Newman, Timothy S.; Gary, G. Allen

    2006-01-01

    A new method to automatically segment arc-like loop structures from intensity images of the Sun's corona is introduced. The method constructively segments credible loop structures by exploiting the Gaussian-like shape of loop cross-sectional intensity profiles. The experimental results show that the method reasonably segments most of the well-defined loops in coronal images. The method is only the second published automated solar loop segmentation method. Its advantage over the other published method is that it operates independently of supplemental time specific data.

  16. Analysis of a fully packed loop model arising in a magnetic Coulomb phase.

    PubMed

    Jaubert, L D C; Haque, M; Moessner, R

    2011-10-21

    The Coulomb phase of spin ice, and indeed the I(c) phase of water ice, naturally realize a fully packed two-color loop model in 3D. We present a detailed analysis of the statistics of these loops: we find loops spanning the system multiple times hosting a finite fraction of all sites while the average loop length remains finite. We contrast the behavior with an analogous 2D model. We connect this body of results to properties of polymers, percolation and insights from Schramm-Loewner evolution processes. We also study another extended degree of freedom, called worms, which appear as "Dirac strings" in spin ice. We discuss implications of these results for the efficiency of numerical cluster algorithms, and address implications for the ordering properties of a broader class of magnetic systems, e.g., with Heisenberg spins, such as CsNiCrF(6) or ZnCr(2)O(4). PMID:22107573

  17. Differential phase shift keyed signal resolver

    NASA Technical Reports Server (NTRS)

    Hopkins, P. M.; Wallingford, W. M. (Inventor)

    1974-01-01

    A differential phase shift keyed signal resolver resolves the differential phase shift in the incoming signal to determine the data content thereof overcoming phase uncertainty without requiring a transmitted reference signal.

  18. Hyperstaticity and loops in frictional granular packings

    NASA Astrophysics Data System (ADS)

    Tordesillas, Antoinette; Lam, Edward; Metzger, Philip T.

    2009-06-01

    The hyperstatic nature of granular packings of perfectly rigid disks is analyzed algebraically and through numerical simulation. The elementary loops of grains emerge as a fundamental element in addressing hyperstaticity. Loops consisting of an odd number of grains behave differently than those with an even number. For odd loops, the latent stresses are exterior and are characterized by the sum of frictional forces around each loop. For even loops, the latent stresses are interior and are characterized by the alternating sum of frictional forces around each loop. The statistics of these two types of loop sums are found to be Gibbsian with a "temperature" that is linear with the friction coefficient μ when μ<1.

  19. Tree-based shortest-path routing algorithm

    NASA Astrophysics Data System (ADS)

    Long, Y. H.; Ho, T. K.; Rad, A. B.; Lam, S. P. S.

    1998-12-01

    A tree-based shortest path routing algorithm is introduced in this paper. With this algorithm, every network node can maintain a shortest path routing tree topology of the network with itself as the root. In this algorithm, every node constructs its own routing tree based upon its neighbors' routing trees. Initially, the routing tree at each node has the root only, the node itself. As information exchanges, every node's routing tree will evolve until a complete tree is obtained. This algorithm is a trade-off between distance vector algorithm and link state algorithm. Loops are automatically deleted, so there is no count-to- infinity effect. A simple routing tree information storage approach and a protocol data until format to transmit the tree information are given. Some special issues, such as adaptation to topology change, implementation of the algorithm on LAN, convergence and computation overhead etc., are also discussed in the paper.

  20. Network Inference Algorithms Elucidate Nrf2 Regulation of Mouse Lung Oxidative Stress

    PubMed Central

    Singhal, Mudita; Malhotra, Deepti; Biswal, Shyam

    2008-01-01

    A variety of cardiovascular, neurological, and neoplastic conditions have been associated with oxidative stress, i.e., conditions under which levels of reactive oxygen species (ROS) are elevated over significant periods. Nuclear factor erythroid 2-related factor (Nrf2) regulates the transcription of several gene products involved in the protective response to oxidative stress. The transcriptional regulatory and signaling relationships linking gene products involved in the response to oxidative stress are, currently, only partially resolved. Microarray data constitute RNA abundance measures representing gene expression patterns. In some cases, these patterns can identify the molecular interactions of gene products. They can be, in effect, proxies for protein–protein and protein–DNA interactions. Traditional techniques used for clustering coregulated genes on high-throughput gene arrays are rarely capable of distinguishing between direct transcriptional regulatory interactions and indirect ones. In this study, newly developed information-theoretic algorithms that employ the concept of mutual information were used: the Algorithm for the Reconstruction of Accurate Cellular Networks (ARACNE), and Context Likelihood of Relatedness (CLR). These algorithms captured dependencies in the gene expression profiles of the mouse lung, allowing the regulatory effect of Nrf2 in response to oxidative stress to be determined more precisely. In addition, a characterization of promoter sequences of Nrf2 regulatory targets was conducted using a Support Vector Machine classification algorithm to corroborate ARACNE and CLR predictions. Inferred networks were analyzed, compared, and integrated using the Collective Analysis of Biological Interaction Networks (CABIN) plug-in of Cytoscape. Using the two network inference algorithms and one machine learning algorithm, a number of both previously known and novel targets of Nrf2 transcriptional activation were identified. Genes predicted as

  1. Loop Dynamics of the Extracellular Domain of Human Tissue Factor and Activation of Factor VIIa

    PubMed Central

    Minazzo, Agnese S.; Darlington, Reuben C.; Ross, J.B. Alexander

    2009-01-01

    Abstract In the crystal structure of the complex between the soluble extracellular domain of tissue factor (sTF) and active-site-inhibited VIIa, residues 91 and 92 in the Pro79-Pro92 loop of sTF interact with the catalytic domain of VIIa. It is not known, however, whether this loop has a role in allosteric activation of VIIa. Time-resolved fluorescence anisotropy measurements of probes covalently bound to sTF mutants E84C and T121C show that binding uninhibited Factor VIIa affects segmental motions in sTF. Glu84 resides in the Pro79-Pro92 loop, and Thr121 resides in the turn between the first and second antiparallel β-strands of the sTF subdomain that interacts with the Gla and EGF1 domains of VIIa; neither Glu84 nor Thr121 makes direct contact with VIIa. Probes bound to T121C report limited segmental flexibility in free sTF, which is lost after VIIa binding. Probes bound to E84C report substantial segmental flexibility in the Pro79-Pro92 loop in free sTF, which is greatly reduced after VIIa binding. Thus, VIIa binding reduces dynamic motions in sTF. In particular, the decrease in the Pro79-Pro92 loop motions indicates that loop entropy has a role in the thermodynamics of the protein-protein interactions involved in allosteric control of VIIa activation. PMID:19167313

  2. Double closed-loop cascade control for lower limb exoskeleton with elastic actuation.

    PubMed

    Zhu, Yanhe; Zheng, Tianjiao; Jin, Hongzhe; Yang, Jixing; Zhao, Jie

    2015-01-01

    Unlike traditional rigid actuators, the significant features of Series Elastic Actuator (SEA) are stable torque control, lower output impedance, impact resistance and energy storage. Recently, SEA has been applied in many exoskeletons. In such applications, a key issue is how to realize the human-exoskeleton movement coordination. In this paper, double closed-loop cascade control for lower limb exoskeleton with SEA is proposed. This control method consists of inner SEA torque loop and outer contact force loop. Utilizing the SEA torque control with a motor velocity loop, actuation performances of SEA are analyzed. An integrated exoskeleton control system is designed, in which joint angles are calculated by internal encoders and resolvers and contact forces are gathered by external pressure sensors. The double closed-loop cascade control model is established based on the feedback signals of internal and external sensor. Movement experiments are accomplished in our prototype of lower limb exoskeleton. Preliminary results indicate the exoskeleton movements with pilot can be realized stably by utilizing this double closed-loop cascade control method. Feasibility of the SEA in our exoskeleton robot and effectiveness of the control method are verified. PMID:26409545

  3. Improved Magnetic-Field-Component Resolvers

    NASA Technical Reports Server (NTRS)

    Garner, H. D.

    1982-01-01

    New resolvers for vectorially summing outputs of aircraft-mounted magnetometers are lighter and more economical to fabricate than conventional electromagnetic resolvers. One resolver is based on potentiometric principles, the second uses polarization filters, and the third has variable-capacitance elements. Optical, capacitive and potentiometric devices have applications in aircraft navigation systems.

  4. Spatially resolved concentration measurements based on backscatter absorption spectroscopy

    NASA Astrophysics Data System (ADS)

    Wang, Ze; Sanders, Scott T.; Robinson, Michael A.

    2016-06-01

    We demonstrate the feasibility of spatially resolved measurements of gas properties using direct absorption spectroscopy in conjunction with backscattered signals. We report a 1-D distribution of H2O mole fraction with a spatial resolution of 5 mm. The peak and average discrepancy between the measured and expected mole fraction are 21.1 and 8.0 %, respectively. The demonstration experiment is related to a diesel aftertreatment system; a selective catalytic reduction brick made of cordierite is used. The brick causes volume scattering interference; advanced baseline fitting based on a genetic algorithm is used to reduce the effects of this interference by a factor of 2.3.

  5. Loop Virasoro Lie conformal algebra

    SciTech Connect

    Wu, Henan Chen, Qiufan; Yue, Xiaoqing

    2014-01-15

    The Lie conformal algebra of loop Virasoro algebra, denoted by CW, is introduced in this paper. Explicitly, CW is a Lie conformal algebra with C[∂]-basis (L{sub i} | i∈Z) and λ-brackets [L{sub i} {sub λ} L{sub j}] = (−∂−2λ)L{sub i+j}. Then conformal derivations of CW are determined. Finally, rank one conformal modules and Z-graded free intermediate series modules over CW are classified.

  6. Closed-Loop Neuroscience and Non-Invasive Brain Stimulation: A Tale of Two Loops.

    PubMed

    Zrenner, Christoph; Belardinelli, Paolo; Müller-Dahlhaus, Florian; Ziemann, Ulf

    2016-01-01

    Closed-loop neuroscience is receiving increasing attention with recent technological advances that enable complex feedback loops to be implemented with millisecond resolution on commodity hardware. We summarize emerging conceptual and methodological frameworks that are available to experimenters investigating a "brain in the loop" using non-invasive brain stimulation and briefly review the experimental and therapeutic implications. We take the view that closed-loop neuroscience in fact deals with two conceptually quite different loops: a "brain-state dynamics" loop, used to couple with and modulate the trajectory of neuronal activity patterns, and a "task dynamics" loop, that is the bidirectional motor-sensory interaction between brain and (simulated) environment, and which enables goal-directed behavioral tasks to be incorporated. Both loops need to be considered and combined to realize the full experimental and therapeutic potential of closed-loop neuroscience. PMID:27092055

  7. Multidimensional smooth loops with universal elasticity

    NASA Astrophysics Data System (ADS)

    Dzhukashev, K. R.; Shelekhov, A. M.

    2015-05-01

    Let \\widetilde E be a universal (isotopically invariant) identity that is derived from the elasticity identity E\\colon (xy)x=x(yx). One of the authors has previously shown that a) each local loop of dimension r with identity \\widetilde E (briefly, a loop \\widetilde E) is a smooth middle Bol loop of dimension r; b) smooth two-dimensional loops \\widetilde E are Lie groups; c) up to isotopy, there exist only two three-dimensional loops \\widetilde E: the loops E_1 and E_2. In this paper, the loops E_1 and E_2 are extended to the multidimensional case. The fact that each smooth loop \\widetilde E of dimension r corresponds to a unique multidimensional three-web on a manifold of dimension 2r is key to our work. In addition, the class of loops under investigation is characterized by the fact that the torsion tensor of the corresponding web has rank 1 (that is, the algebra generated by this tensor has a one-dimensional derived algebra). This enables us to express the differential equations of the problem in an invariant form. The system of equations thus obtained was found to be amenable to integration in the most general case, and the equations of the required loops have been obtained in local coordinates. Bibliography: 17 titles.

  8. Costas loop lock detection in the advanced receiver

    NASA Technical Reports Server (NTRS)

    Mileant, A.; Hinedi, S.

    1989-01-01

    The advanced receiver currently being developed uses a Costas digital loop to demodulate the subcarrier. Previous analyses of lock detector algorithms for Costas loops have ignored the effects of the inherent correlation between the samples of the phase-error process. Accounting for this correlation is necessary to achieve the desired lock-detection probability for a given false-alarm rate. Both analysis and simulations are used to quantify the effects of phase correlation on lock detection for the square-law and the absolute-value type detectors. Results are obtained which depict the lock-detection probability as a function of loop signal-to-noise ratio for a given false-alarm rate. The mathematical model and computer simulation show that the square-law detector experiences less degradation due to phase jitter than the absolute-value detector and that the degradation in detector signal-to-noise ratio is more pronounced for square-wave than for sine-wave signals.

  9. Analysis of the loop length distribution for the negative-weight percolation problem in dimensions d=2 through d=6.

    PubMed

    Claussen, G; Apolo, L; Melchert, O; Hartmann, A K

    2012-11-01

    We consider the negative weight percolation (NWP) problem on hypercubic lattice graphs with fully periodic boundary conditions in all relevant dimensions from d=2 to the upper critical dimension d=6. The problem exhibits edge weights drawn from disorder distributions that allow for weights of either sign. We are interested in the full ensemble of loops with negative weight, i.e., nontrivial (system spanning) loops as well as topologically trivial ("small") loops. The NWP phenomenon refers to the disorder driven proliferation of system spanning loops of total negative weight. While previous studies where focused on the latter loops, we here put under scrutiny the ensemble of small loops. Our aim is to characterize-using this extensive and exhaustive numerical study-the loop length distribution of the small loops right at and below the critical point of the hypercubic setups by means of two independent critical exponents. These can further be related to the results of previous finite-size scaling analyses carried out for the system spanning loops. For the numerical simulations, we employed a mapping of the NWP model to a combinatorial optimization problem that can be solved exactly by using sophisticated matching algorithms. This allowed us to study here numerically exact very large systems with high statistics. PMID:23214907

  10. Solar Load Voltage Tracking for Water Pumping: An Algorithm

    NASA Astrophysics Data System (ADS)

    Kappali, M.; Udayakumar, R. Y.

    2014-07-01

    Maximum power is to be harnessed from solar photovoltaic (PV) panel to minimize the effective cost of solar energy. This is accomplished by maximum power point tracking (MPPT). There are different methods to realise MPPT. This paper proposes a simple algorithm to implement MPPT lv method in a closed loop environment for centrifugal pump driven by brushed PMDC motor. Simulation testing of the algorithm is done and the results are found to be encouraging and supportive of the proposed method MPPT lv .

  11. CORONAL FUZZINESS MODELED WITH PULSE-HEATED MULTI-STRANDED LOOP SYSTEMS

    SciTech Connect

    Guarrasi, Massimiliano; Reale, Fabio; Peres, Giovanni

    2010-08-10

    Coronal active regions are observed to get increasingly fuzzy (i.e., increasingly confused and uniform) in increasingly hard energy bands or lines. We explain this as evidence of fine multi-temperature structure of coronal loops. To this end, we model bundles of loops made of thin strands, each heated by short and intense heat pulses. For simplicity, we assume that the heat pulses are all equal and triggered only once in each strand at a random time. The pulse intensity and cadence are selected so as to have steady active region loops ({approx}3 MK) on average. We compute the evolution of the confined heated plasma with a hydrodynamic loop model. We then compute the emission along each strand in several spectral lines, from cool ({<=}1 MK), to warm (2-3 MK) lines, detectable with Hinode/Extreme-ultraviolet Imaging Spectrometer, to hot X-ray lines. The strands are then put side by side to construct an active region loop bundle. We find that in the warm lines (2-3 MK) the loop emission fills all the available image surface. Therefore, the emission appears quite uniform and it is difficult to resolve the single loops, while in the cool lines the loops are considerably more contrasted and the region is less fuzzy. The main reasons for this effect are that, during their evolution, i.e., pulse heating and slow cooling, each strand spends a relatively long time at temperatures around 2-3 MK and it has a high emission measure during that phase, so the whole region appears more uniform or smudged. We predict that fuzziness should be reduced in the hot UV and X-ray lines.

  12. The Quiet Sun Network at Subarcsecond Resolution: VAULT Observations and Radiative Transfer Modeling of Cool Loops

    NASA Astrophysics Data System (ADS)

    Patsourakos, S.; Gouttebroze, P.; Vourlidas, A.

    2007-08-01

    One of the most enigmatic regions of the solar atmosphere is the transition region (TR), corresponding to plasmas with temperatures intermediate of the cool, few thousand K, chromosphere and the hot, few million K, corona. The traditional view is that the TR emission originates from a thin thermal interface in hot coronal structures, connecting their chromosphere with their corona. This paradigm fails badly for cool plasmas (~T<105 K), since it predicts emission orders of magnitude less than what it is observed. It was therefore proposed that the ``missing'' TR emission could originate from tiny, isolated from the hot corona, cool loops at TR temperatures. A major problem in investigating this proposal is the very small sizes of the hypothesized cool loops. Here, we report the first spatially resolved observations of subarcsecond-scale looplike structures seen in the Lyα line made by the Very High Angular Resolution Ultraviolet Telescope (VAULT). The subarcsecond (~0.3") resolution of VAULT allows us to directly view and resolve looplike structures in the quiet Sun network. We compare the observed intensities of these structures with simplified radiative transfer models of cool loops. The reasonable agreement between the models and the observations indicates that an explanation of the observed fine structure in terms of cool loops is plausible.

  13. Extended loop representation of quantum gravity

    SciTech Connect

    Di Bartolo, C. ); Gambini, R.; Griego, J. )

    1995-01-15

    A new representation of quantum gravity is developed. This formulation is based on an extension of the group of loops. The enlarged group that we call the extended loop group behaves locally as an infinite dimensional Lie group. Quantum gravity can be realized on the state space of extended loop-dependent wave functions. The extended representation generalizes the loop representation and contains this representation as a particular case. The resulting diffeomorphism and Hamiltonian constraints take a very simple form and allow us to apply functional methods and simplify the loop calculus. In particular we show that the constraints are linear in the momenta. The nondegenerate solutions known in the loop representation are also solutions of the constraints in the new representation. An approach to the regularization problems associated with the formal calculus is performed. We show that the solutions are generalized knot invariants, smooth in the extended variables, and any framing is unnecessary.

  14. Optimal Pipe Size Design for Looped Irrigation Water Supply System Using Harmony Search: Saemangeum Project Area

    PubMed Central

    Lee, Ho Min; Sadollah, Ali

    2015-01-01

    Water supply systems are mainly classified into branched and looped network systems. The main difference between these two systems is that, in a branched network system, the flow within each pipe is a known value, whereas in a looped network system, the flow in each pipe is considered an unknown value. Therefore, an analysis of a looped network system is a more complex task. This study aims to develop a technique for estimating the optimal pipe diameter for a looped agricultural irrigation water supply system using a harmony search algorithm, which is an optimization technique. This study mainly serves two purposes. The first is to develop an algorithm and a program for estimating a cost-effective pipe diameter for agricultural irrigation water supply systems using optimization techniques. The second is to validate the developed program by applying the proposed optimized cost-effective pipe diameter to an actual study region (Saemangeum project area, zone 6). The results suggest that the optimal design program, which applies an optimization theory and enhances user convenience, can be effectively applied for the real systems of a looped agricultural irrigation water supply. PMID:25874252

  15. Numerical Algorithms Based on Biorthogonal Wavelets

    NASA Technical Reports Server (NTRS)

    Ponenti, Pj.; Liandrat, J.

    1996-01-01

    Wavelet bases are used to generate spaces of approximation for the resolution of bidimensional elliptic and parabolic problems. Under some specific hypotheses relating the properties of the wavelets to the order of the involved operators, it is shown that an approximate solution can be built. This approximation is then stable and converges towards the exact solution. It is designed such that fast algorithms involving biorthogonal multi resolution analyses can be used to resolve the corresponding numerical problems. Detailed algorithms are provided as well as the results of numerical tests on partial differential equations defined on the bidimensional torus.

  16. Magnetic monopole in the loop representation

    SciTech Connect

    Leal, Lorenzo; Lopez, Alexander

    2006-01-15

    We quantize, within the Loop Representation formalism, the electromagnetic field in the presence of a static magnetic pole. It is found that the loop-dependent physical wave functionals of the quantum Maxwell theory become multivalued, through a topological phase factor depending on the solid angle subtended at the monopole by a surface bounded by the loop. It is discussed how this fact generalizes what occurs in ordinary quantum mechanics in multiply connected spaces.

  17. Biopolymer hairpin loops sustained by polarons

    NASA Astrophysics Data System (ADS)

    Chakrabarti, B.; Piette, B. M. A. G.; Zakrzewski, W. J.

    2012-08-01

    We show that polarons can sustain looplike configurations in flexible biopolymers and that the size of the loops depend on both the flexural rigidity of the polymer and the electron-phonon coupling constant. In particular we show that for single stranded DNA (ssDNA) and polyacetylene such loops can have as few as seven monomers. We also show that these configurations are very stable under thermal fluctuations and so could facilitate the formation of hairpin loops of ssDNA.

  18. LMFBR with booster pump in pumping loop

    DOEpatents

    Rubinstein, H.J.

    1975-10-14

    A loop coolant circulation system is described for a liquid metal fast breeder reactor (LMFBR) utilizing a low head, high specific speed booster pump in the hot leg of the coolant loop with the main pump located in the cold leg of the loop, thereby providing the advantages of operating the main pump in the hot leg with the reliability of cold leg pump operation.

  19. Loop anomalies in the causal approach

    NASA Astrophysics Data System (ADS)

    Grigore, Dan-Radu

    2015-01-01

    We consider gauge models in the causal approach and study one-loop contributions to the chronological products and the anomalies they produce. We prove that in order greater than 4 there are no one-loop anomalies. Next we analyze one-loop anomalies in the second- and third-order of the perturbation theory. We prove that the even parity contributions (with respect to parity) do not produce anomalies; for the odd parity contributions we reobtain the well-known result.

  20. Stability of Bareiss algorithm

    NASA Astrophysics Data System (ADS)

    Bojanczyk, Adam W.; Brent, Richard P.; de Hoog, F. R.

    1991-12-01

    In this paper, we present a numerical stability analysis of Bareiss algorithm for solving a symmetric positive definite Toeplitz system of linear equations. We also compare Bareiss algorithm with Levinson algorithm and conclude that the former has superior numerical properties.

  1. Binary phase locked loops for Omega receivers

    NASA Technical Reports Server (NTRS)

    Chamberlin, K.

    1974-01-01

    An all-digital phase lock loop (PLL) is considered because of a number of problems inherent in an employment of analog PLL. The digital PLL design presented solves these problems. A single loop measures all eight Omega time slots. Memory-aiding leads to the name of this design, the memory-aided phase lock loop (MAPLL). Basic operating principles are discussed and the superiority of MAPLL over the conventional digital phase lock loop with regard to the operational efficiency for Omega applications is demonstrated.

  2. Loop statistics in polymers in crowded environment

    NASA Astrophysics Data System (ADS)

    Haydukivska, K.; Blavatska, V.

    2016-02-01

    We analyze the probability to find a single loop in a long flexible polymer chain in disordered environment in d dimensions. The structural defects are considered to be correlated on large distances r according to a power law ˜r-a. Working within the frames of continuous chain model and applying the direct polymer renormalization scheme, we obtain the values of critical exponents governing the scaling of probabilities to find the loops of various positions along the chain as function of loops' length. Our results quantitatively reveal that the presence of structural defects in environment decreases the probability of loop formation in polymer macromolecules.

  3. Multi-instrument observations of coronal loops

    NASA Astrophysics Data System (ADS)

    Scott, Jason Terrence

    This document exhibits results of analysis from data collected with multiple EUV satellites (SOHO, TRACE, STEREO, Hinode, and SDO). The focus is the detailed observation of coronal loops using multiple instruments, i.e. filter imagers and spectrometers. Techniques for comparing the different instruments and deriving loop parameters are demonstrated. Attention is given to the effects the different instruments may introduce into the data and their interpretation. The assembled loop parameters are compared to basic energy balance equations and scaling laws. Discussion of the blue-shifted, asymmetric, and line broadened spectral line profiles near the footpoints of coronal loops is made. The first quantitative analysis of the anti-correlation between intensity and spectral line broadening for isolated regions along loops and their footpoints is presented. A magnetic model of an active region shows where the separatrices meet the photospheric boundary. At the boundary, the spectral data reveal concentrated regions of increased blue-shifted outflows, blue wing asymmetry, and line broadening. This is found just outside the footpoints of bright loops. The intensity and line broadening in this region are anti-correlated. A comparison of the similarities in the spectroscopic structure near the footpoints of the arcade loops and more isolated loops suggests the notion of consistent structuring for the bright loops forming an apparent edge of an active region core.

  4. A generic sun-tracking algorithm for on-axis solar collector in mobile platforms

    NASA Astrophysics Data System (ADS)

    Lai, An-Chow; Chong, Kok-Keong; Lim, Boon-Han; Ho, Ming-Cheng; Yap, See-Hao; Heng, Chun-Kit; Lee, Jer-Vui; King, Yeong-Jin

    2015-04-01

    This paper proposes a novel dynamic sun-tracking algorithm which allows accurate tracking of the sun for both non-concentrated and concentrated photovoltaic systems located on mobile platforms to maximize solar energy extraction. The proposed algorithm takes not only the date, time, and geographical information, but also the dynamic changes of coordinates of the mobile platforms into account to calculate the sun position angle relative to ideal azimuth-elevation axes in real time using general sun-tracking formulas derived by Chong and Wong. The algorithm acquires data from open-loop sensors, i.e. global position system (GPS) and digital compass, which are readily available in many off-the-shelf portable gadgets, such as smart phone, to instantly capture the dynamic changes of coordinates of mobile platforms. Our experiments found that a highly accurate GPS is not necessary as the coordinate changes of practical mobile platforms are not fast enough to produce significant differences in the calculation of the incident angle. On the contrary, it is critical to accurately identify the quadrant and angle where the mobile platforms are moving toward in real time, which can be resolved by using digital compass. In our implementation, a noise filtering mechanism is found necessary to remove unexpected spikes in the readings of the digital compass to ensure stability in motor actuations and effectiveness in continuous tracking. Filtering mechanisms being studied include simple moving average and linear regression; the results showed that a compound function of simple moving average and linear regression produces a better outcome. Meanwhile, we found that a sampling interval is useful to avoid excessive motor actuations and power consumption while not sacrificing the accuracy of sun-tracking.

  5. Ultrashort-pulse measurement using noninstantaneous nonlinearities: Raman effects in frequency-resolved optical gating

    SciTech Connect

    DeLong, K.W.; Ladera, C.L.; Trebino, R.; Kohler, B.; Wilson, K.R.

    1995-03-01

    Ultrashort-pulse-characterization techniques generally require instantaneously responding media. We show that this is not the case for frequency-resolved optical gating (FROG). We include, as an example, the noninstantaneous Raman response of fused silica, which can cause errors in the retrieved pulse width of as much as 8% for a 25-fs pulse in polarization-gate FROG. We present a modified pulse-retrieval algorithm that deconvolves such slow effects and use it to retrieve pulses of any width. In experiments with 45-fs pulses this algorithm achieved better convergence and yielded a shorter pulse than previous FROG algorithms.

  6. Anisotropic loop quantum cosmology with self-dual variables

    NASA Astrophysics Data System (ADS)

    Wilson-Ewing, Edward

    2016-04-01

    A loop quantization of the diagonal class A Bianchi models starting from the complex-valued self-dual connection variables is presented in this paper. The basic operators in the quantum theory correspond to areas and generalized holonomies of the Ashtekar connection, and the reality conditions are implemented via the choice of the inner product on the kinematical Hilbert space. The action of the Hamiltonian constraint operator is given explicitly for the case when the matter content is a massless scalar field (in which case the scalar field can be used as a relational clock), and it is shown that the big bang and big crunch singularities are resolved in the sense that singular and nonsingular states decouple under the action of the Hamiltonian constraint operator.

  7. Thermal 2-loop master spectral function at finite momentum

    NASA Astrophysics Data System (ADS)

    Laine, M.

    2013-05-01

    When considering NLO corrections to thermal particle production in the "relativistic" regime, in which the invariant mass squared of the produced particle is {{{K}}^2} ( πT)2, then the production rate can be expressed as a sum of a few universal "master" spectral functions. Taking the most complicated 2-loop master as an example, a general strategy for obtaining a convergent 2-dimensional integral representation is suggested. The analysis applies both to bosonic and fermionic statistics, and shows that for this master the non-relativistic approximation is only accurate for {{{K}}^2} (8 πT)2, whereas the zero-momentum approximation works surprisingly well. Once the simpler masters have been similarly resolved, NLO results for quantities such as the right-handed neutrino production rate from a Standard Model plasma or the dilepton production rate from a QCD plasma can be assembled for {{{K}}^2} ( πT)2.

  8. Attitude-Control Algorithm for Minimizing Maneuver Execution Errors

    NASA Technical Reports Server (NTRS)

    Acikmese, Behcet

    2008-01-01

    A G-RAC attitude-control algorithm is used to minimize maneuver execution error in a spacecraft with a flexible appendage when said spacecraft must induce translational momentum by firing (in open loop) large thrusters along a desired direction for a given period of time. The controller is dynamic with two integrators and requires measurement of only the angular position and velocity of the spacecraft. The global stability of the closed-loop system is guaranteed without having access to the states describing the dynamics of the appendage and with severe saturation in the available torque. Spacecraft apply open-loop thruster firings to induce a desired translational momentum with an extended appendage. This control algorithm will assist this maneuver by stabilizing the attitude dynamics around a desired orientation, and consequently minimize the maneuver execution errors.

  9. Closed-Loop Neuroscience and Non-Invasive Brain Stimulation: A Tale of Two Loops

    PubMed Central

    Zrenner, Christoph; Belardinelli, Paolo; Müller-Dahlhaus, Florian; Ziemann, Ulf

    2016-01-01

    Closed-loop neuroscience is receiving increasing attention with recent technological advances that enable complex feedback loops to be implemented with millisecond resolution on commodity hardware. We summarize emerging conceptual and methodological frameworks that are available to experimenters investigating a “brain in the loop” using non-invasive brain stimulation and briefly review the experimental and therapeutic implications. We take the view that closed-loop neuroscience in fact deals with two conceptually quite different loops: a “brain-state dynamics” loop, used to couple with and modulate the trajectory of neuronal activity patterns, and a “task dynamics” loop, that is the bidirectional motor-sensory interaction between brain and (simulated) environment, and which enables goal-directed behavioral tasks to be incorporated. Both loops need to be considered and combined to realize the full experimental and therapeutic potential of closed-loop neuroscience. PMID:27092055

  10. The analytical basis for the resonances and anti-resonances of loop antennas and meta-material ring resonators

    NASA Astrophysics Data System (ADS)

    McKinley, A. F.; White, T. P.; Maksymov, I. S.; Catchpole, K. R.

    2012-11-01

    Interest in the electromagnetic properties of loop structures has surged with the recent appearance of split-ring resonator meta-materials (SRRs) and nano-antennas. Understanding the resonances, anti-resonances, and harmonics of these loops is key to understanding their response to a wide range of excitation wavelengths. We present the classical analytical solution for the input impedance of a loop structure with circumference on the order of the wavelength, and we show how to identify these resonances from the function. We transform the classical solution into a new RLC formulation and show that each natural mode of the loop can be represented as a series resonant circuit, such that the full response function can be resolved by placing all of these circuits in parallel. We show how this formulation applies to SRRs.

  11. UWB communication receiver feedback loop

    DOEpatents

    Spiridon, Alex; Benzel, Dave; Dowla, Farid U.; Nekoogar, Faranak; Rosenbury, Erwin T.

    2007-12-04

    A novel technique and structure that maximizes the extraction of information from reference pulses for UWB-TR receivers is introduced. The scheme efficiently processes an incoming signal to suppress different types of UWB as well as non-UWB interference prior to signal detection. Such a method and system adds a feedback loop mechanism to enhance the signal-to-noise ratio of reference pulses in a conventional TR receiver. Moreover, sampling the second order statistical function such as, for example, the autocorrelation function (ACF) of the received signal and matching it to the ACF samples of the original pulses for each transmitted bit provides a more robust UWB communications method and system in the presence of channel distortions.

  12. Closed loop steam cooled airfoil

    SciTech Connect

    Widrig, Scott M.; Rudolph, Ronald J.; Wagner, Gregg P.

    2006-04-18

    An airfoil, a method of manufacturing an airfoil, and a system for cooling an airfoil is provided. The cooling system can be used with an airfoil located in the first stages of a combustion turbine within a combined cycle power generation plant and involves flowing closed loop steam through a pin array set within an airfoil. The airfoil can comprise a cavity having a cooling chamber bounded by an interior wall and an exterior wall so that steam can enter the cavity, pass through the pin array, and then return to the cavity to thereby cool the airfoil. The method of manufacturing an airfoil can include a type of lost wax investment casting process in which a pin array is cast into an airfoil to form a cooling chamber.

  13. Delay locked loop integrated circuit.

    SciTech Connect

    Brocato, Robert Wesley

    2007-10-01

    This report gives a description of the development of a Delay Locked Loop (DLL) integrated circuit (IC). The DLL was developed and tested as a stand-alone IC test chip to be integrated into a larger application specific integrated circuit (ASIC), the Quadrature Digital Waveform Synthesizer (QDWS). The purpose of the DLL is to provide a digitally programmable delay to enable synchronization between an internal system clock and external peripherals with unknown clock skew. The DLL was designed and fabricated in the IBM 8RF process, a 0.13 {micro}m CMOS process. It was designed to operate with a 300MHz clock and has been tested up to 500MHz.

  14. Closing the loop with blur

    NASA Astrophysics Data System (ADS)

    Tani, Jacopo

    A great variety of systems use image sensors to provide measurements for closed loop operation. A drawback of using image sensors in real-time feedback is that they provide measurements at slower sampling rates as compared to the actuators, typically around 30 Hz for CCD cameras, hence acting as the bottleneck for closed loop control bandwidths. While high speed cameras exist, higher frame rates imply an upper bound on exposures which lowers the signal-to-noise-ratio (SNR), reducing measurements accuracy. The integrative nature of image sensors though offers the opportunity to prolong the exposure window and collect motion blurred measurements. This research describes how to exploit the dynamic information of observed system outputs, encoded in motion blur, to control fast systems at the fast rate through slow rate image sensors. In order to achieve this objective it is necessary to (a) design a controller providing fast rate input to the system based on the slow image measurements. Ideally such a controller would require a fast rate estimate of the system's state variables in order to provide the necessary control action, therefore an (b) image blur based estimator is to be developed. State estimators typically need a model of the system in order to provide their estimates, so (c) a system identification problem has to be addressed, where a reliable model describing the frequency content of the system, up to frequencies corresponding to the fast rate, has to be determined through slow rate image sensor measurements. Alternatively when such a procedure is not possible for lack, e.g., of knowledge of the input to the system, then (d) a method to reconstruct the output signal frequency content up to frequencies above those set by the limitations of the sampling theorem is to be devised. Therefore in order to "close the loop with blur", this work describes how to pose and solve the problems of, namely: system identification , state estimation, closed loop control and

  15. On the feasibility of closed-loop control of intra-aortic balloon pumping

    NASA Technical Reports Server (NTRS)

    Clark, J. W., Jr.; Bourland, H. M.; Kane, G. R.

    1973-01-01

    A closed-loop control scheme for the control of intra-aortic balloon pumping has been developed and tested in dog experiments. A performance index reflecting the general objectives of balloon-assist pumping is developed and a modified steepest ascent control algorithm is utilized for the selection of a proper operating point for the balloon during its pumping cycle. This paper attempts to indicate the feasibility of closed-loop control of balloon pumping, and particularly its flexibility in achieving both diastolic augmentation of mean aortic pressure and control of the level of end-diastolic pressure (EDP) an important factor in reducing heart work.

  16. A method to resolve low velocities in a PIV system

    NASA Astrophysics Data System (ADS)

    Bharadwaj, Sunil; Alam, Meheboob

    2015-11-01

    A method is proposed to improve the velocity-dynamic range (VDR) of particle-image velocimetry (PIV) technique. This method uses two different timings of a pulsed laser and an outlier detection technique that helped to measure very low velocities, bypassing the limits set by the VDR of the PIV-system. The lower limit of the resolvable velocity is not set by the algorithm but by the laser-timings. The reliability of the method is verified by carrying our planar measurements of the mean and fluctuation velocities in an axisymmetric jet at a Reynolds number of about 3500. The radial velocity, which is usually an order-of-magnitude lower than the axial velocity, is successfully resolved in the ambient region of the jet as compared to results obtained by employing the post-processing techniques of the standard PIV-system. Overall, the proposed method seems to increase the velocity-dynamic range of PIV-algorithm to capture low-velocities in an otherwise fast flow. Thsi work is supported by the BARC, Government of India (BARC/MA/4350).

  17. Three-loop cusp anomalous dimension and a conjecture for n loops

    NASA Astrophysics Data System (ADS)

    Kidonakis, Nikolaos

    2016-05-01

    I present analytical expressions for the massive cusp anomalous dimension in QCD through three loops, first calculated in 2014, in terms of elementary functions and ordinary polylogarithms. I observe interesting relations between the results at different loops and provide a conjecture for the n-loop cusp anomalous dimension in terms of the lower-loop results. I also present numerical results and simple approximate formulas for the cusp anomalous dimension relevant to top-quark production.

  18. Maximizing the biochemical resolving power of fluorescence microscopy.

    PubMed

    Esposito, Alessandro; Popleteeva, Marina; Venkitaraman, Ashok R

    2013-01-01

    Most recent advances in fluorescence microscopy have focused on achieving spatial resolutions below the diffraction limit. However, the inherent capability of fluorescence microscopy to non-invasively resolve different biochemical or physical environments in biological samples has not yet been formally described, because an adequate and general theoretical framework is lacking. Here, we develop a mathematical characterization of the biochemical resolution in fluorescence detection with Fisher information analysis. To improve the precision and the resolution of quantitative imaging methods, we demonstrate strategies for the optimization of fluorescence lifetime, fluorescence anisotropy and hyperspectral detection, as well as different multi-dimensional techniques. We describe optimized imaging protocols, provide optimization algorithms and describe precision and resolving power in biochemical imaging thanks to the analysis of the general properties of Fisher information in fluorescence detection. These strategies enable the optimal use of the information content available within the limited photon-budget typically available in fluorescence microscopy. This theoretical foundation leads to a generalized strategy for the optimization of multi-dimensional optical detection, and demonstrates how the parallel detection of all properties of fluorescence can maximize the biochemical resolving power of fluorescence microscopy, an approach we term Hyper Dimensional Imaging Microscopy (HDIM). Our work provides a theoretical framework for the description of the biochemical resolution in fluorescence microscopy, irrespective of spatial resolution, and for the development of a new class of microscopes that exploit multi-parametric detection systems. PMID:24204821

  19. Maximizing the Biochemical Resolving Power of Fluorescence Microscopy

    PubMed Central

    Esposito, Alessandro; Popleteeva, Marina; Venkitaraman, Ashok R.

    2013-01-01

    Most recent advances in fluorescence microscopy have focused on achieving spatial resolutions below the diffraction limit. However, the inherent capability of fluorescence microscopy to non-invasively resolve different biochemical or physical environments in biological samples has not yet been formally described, because an adequate and general theoretical framework is lacking. Here, we develop a mathematical characterization of the biochemical resolution in fluorescence detection with Fisher information analysis. To improve the precision and the resolution of quantitative imaging methods, we demonstrate strategies for the optimization of fluorescence lifetime, fluorescence anisotropy and hyperspectral detection, as well as different multi-dimensional techniques. We describe optimized imaging protocols, provide optimization algorithms and describe precision and resolving power in biochemical imaging thanks to the analysis of the general properties of Fisher information in fluorescence detection. These strategies enable the optimal use of the information content available within the limited photon-budget typically available in fluorescence microscopy. This theoretical foundation leads to a generalized strategy for the optimization of multi-dimensional optical detection, and demonstrates how the parallel detection of all properties of fluorescence can maximize the biochemical resolving power of fluorescence microscopy, an approach we term Hyper Dimensional Imaging Microscopy (HDIM). Our work provides a theoretical framework for the description of the biochemical resolution in fluorescence microscopy, irrespective of spatial resolution, and for the development of a new class of microscopes that exploit multi-parametric detection systems. PMID:24204821

  20. Dihedral-like constructions of automorphic loops

    NASA Astrophysics Data System (ADS)

    Aboras, Mouna

    In this dissertation we study dihedral-like constructions of automorphic loops. Automorphic loops are loops in which all inner mappings are automorphisms. We start by describing a generalization of the dihedral construction for groups. Namely, if (G, +) is an abelian group, m > 1 and alpha ∈2 Aut(G), let Dih(m, G, alpha) on Zm x G be defined by. (i, u)(j, v) = (i + j, ((--1)ju + v)alpha ij). We prove that the resulting loop is automorphic if and only if m = 2 or (alpha2 = 1 and m is even) or (m is odd, alpha = 1 and exp(G) ≤ 2). In the last case, the loop is a group. The case m = 2 was introduced by Kinyon, Kunen, Phillips, and Vojtechovsky. We study basic structural properties of dihedral-like automorphic loops. We describe certain subloops, including: nucleus, commutant, center, associator subloop and derived subloop. We prove theorems for dihedral-like automorphic loops analogous to the Cauchy and Lagrange theorems for groups, and further we discuss the coset decomposition in dihedral-like automorphic loops. We show that two finite dihedral-like automorphic loops Dih( m, G, alpha) and Dih(m¯, G¯, [special character omitted]) are isomorphic if and only if m = m¯, G ≅ G¯ and alpha is conjugate to [special character omitted] in Aut(G). We describe the automorphism group of Q and its subgroup consisting of inner mappings of Q. Finally, due to the solution to the isomorphism problem, we are interested in studying conjugacy classes of automorphism groups of finite abelian groups. Then we describe all dihedral-like automorphic loops of order < 128 up to isomorphism. We conclude with a description of all dihedral-like automorphic loops of order < 64 up to isotopism.

  1. Magnetic loop emergence within a granule

    NASA Astrophysics Data System (ADS)

    Gömöry, P.; Beck, C.; Balthasar, H.; Rybák, J.; Kučera, A.; Koza, J.; Wöhl, H.

    2010-02-01

    Aims: We investigate the temporal evolution of magnetic flux emerging within a granule in the quiet-Sun internetwork at disk center. Methods: We combined IR spectropolarimetry of high angular resolution performed in two Fe i lines at 1565 nm with speckle-reconstructed G-band imaging. We determined the magnetic field parameters by a LTE inversion of the full Stokes vector using the SIR code, and followed their evolution in time. To interpret the observations, we created a geometrical model of a rising loop in 3D. The relevant parameters of the loop were matched to the observations where possible. We then synthesized spectra from the 3D model for a comparison to the observations. Results: We found signatures of magnetic flux emergence within a growing granule. In the early phases, a horizontal magnetic field with a distinct linear polarization signal dominated the emerging flux. Later on, two patches of opposite circular polarization signal appeared symmetrically on either side of the linear polarization patch, indicating a small loop-like structure. The mean magnetic flux density of this loop was roughly 450 G, with a total magnetic flux of around 3 × 1017 Mx. During the ~12 min episode of loop occurrence, the spatial extent of the loop increased from about 1 to 2 arcsec. The middle part of the appearing feature was blueshifted during its occurrence, supporting the scenario of an emerging loop. There is also clear evidence for the interaction of one loop footpoint with a preexisting magnetic structure of opposite polarity. The temporal evolution of the observed spectra is reproduced to first order by the spectra derived from the geometrical model. During the phase of clearest visibility of the loop in the observations, the observed and synthetic spectra match quantitatively. Conclusions: The observed event can be explained as a case of flux emergence in the shape of a small-scale loop. The fast disappearance of the loop at the end could possibly be due to magnetic

  2. Resolving Seamounts in Satellite Altimetry

    NASA Astrophysics Data System (ADS)

    Marks, K. M.; Smith, W. H.

    2006-12-01

    We have examined three factors influencing the use of satellite altimeter data to map seamounts and guyots in the deep ocean: (1) the resolution of seamount and guyot gravity anomalies by altimetry; (2) the non-linearity of the relationship between gravity and bathymetry; and (3) the homogeneity of the mass density within the seamount or guyot. When altimeter data are used to model the marine gravity anomaly field the result may have limited resolution due to noise levels in the altimeter data, track spacing of the satellite profiles, inclination angles of the orbits, and filters used to combine and interpolate the data (Sandwell and Smith, JGR, 1997). We compared the peak-to-trough amplitude of gravity anomalies in Sandwell and Smith`'s version 15.1 field to peak-to-trough amplitudes measured by gravimeters on board ships. The satellite gravity field amplitudes match ship measurements well over seamounts and guyots having volumes exceeding ~2000 km3. Over smaller volume seamounts, where the anomalies have most of their power at quite short wavelengths, the satellite field under-estimates the anomaly amplitude. If less filtering could be done, or a new mission with a lower noise level were flown, more of the anomalies associated with small seamounts might be resolved. Smith and Sandwell (Science, 1997) predicted seafloor topography from altimetric gravity assuming that the density of seafloor topography is nearly constant over ~100 km distances, and that the relationship between gravity and topography may be approximated by a liner filter over those distances. In fact, the true theoretical relationship is non-linear (Parker, Geophys. J. R. astr. Soc, 1972); it can be expressed as an N-th order expansion, with the N=1 term representing a linear filter and the N>1 terms accounting for higher-order corrections. We find that N=2 is a sufficient approximation at both seamounts and guyots. Constant density models of large volume guyots do not fit the observed gravity

  3. Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells.

    PubMed

    Priest, David G; Kumar, Sandip; Yan, Yan; Dunlap, David D; Dodd, Ian B; Shearwin, Keith E

    2014-10-21

    Eukaryotic gene regulation involves complex patterns of long-range DNA-looping interactions between enhancers and promoters, but how these specific interactions are achieved is poorly understood. Models that posit other DNA loops--that aid or inhibit enhancer-promoter contact--are difficult to test or quantitate rigorously in eukaryotic cells. Here, we use the well-characterized DNA-looping proteins Lac repressor and phage λ CI to measure interactions between pairs of long DNA loops in E. coli cells in the three possible topological arrangements. We find that side-by-side loops do not affect each other. Nested loops assist each other's formation consistent with their distance-shortening effect. In contrast, alternating loops, where one looping element is placed within the other DNA loop, inhibit each other's formation, thus providing clear support for the loop domain model for insulation. Modeling shows that combining loop assistance and loop interference can provide strong specificity in long-range interactions. PMID:25288735

  4. Thumb-loops up for catalysis: a structure/function investigation of a functional loop movement in a GH11 xylanase

    PubMed Central

    Paës, Gabriel; Cortés, Juan; Siméon, Thierry; O'Donohue, Michael J.; Tran, Vinh

    2012-01-01

    Dynamics is a key feature of enzyme catalysis. Unfortunately, current experimental and computational techniques do not yet provide a comprehensive understanding and description of functional macromolecular motions. In this work, we have extended a novel computational technique, which combines molecular modeling methods and robotics algorithms, to investigate functional motions of protein loops. This new approach has been applied to study the functional importance of the so-called thumb-loop in the glycoside hydrolase family 11 xylanase from Thermobacillus xylanilyticus (Tx-xyl). The results obtained provide new insight into the role of the loop in the glycosylation/deglycosylation catalytic cycle, and underline the key importance of the nature of the residue located at the tip of the thumb-loop. The effect of mutations predicted in silico has been validated by in vitro site-directed mutagenesis experiments. Overall, we propose a comprehensive model of Tx-xyl catalysis in terms of substrate and product dynamics by identifying the action of the thumb-loop motion during catalysis. PMID:24688637

  5. Depth resolved hyperspectral imaging spectrometer based on structured light illumination and Fourier transform interferometry.

    PubMed

    Choi, Heejin; Wadduwage, Dushan; Matsudaira, Paul T; So, Peter T C

    2014-10-01

    A depth resolved hyperspectral imaging spectrometer can provide depth resolved imaging both in the spatial and the spectral domain. Images acquired through a standard imaging Fourier transform spectrometer do not have the depth-resolution. By post processing the spectral cubes (x, y, λ) obtained through a Sagnac interferometer under uniform illumination and structured illumination, spectrally resolved images with depth resolution can be recovered using structured light illumination algorithms such as the HiLo method. The proposed scheme is validated with in vitro specimens including fluorescent solution and fluorescent beads with known spectra. The system is further demonstrated in quantifying spectra from 3D resolved features in biological specimens. The system has demonstrated depth resolution of 1.8 μm and spectral resolution of 7 nm respectively. PMID:25360367

  6. Depth resolved hyperspectral imaging spectrometer based on structured light illumination and Fourier transform interferometry

    PubMed Central

    Choi, Heejin; Wadduwage, Dushan; Matsudaira, Paul T.; So, Peter T.C.

    2014-01-01

    A depth resolved hyperspectral imaging spectrometer can provide depth resolved imaging both in the spatial and the spectral domain. Images acquired through a standard imaging Fourier transform spectrometer do not have the depth-resolution. By post processing the spectral cubes (x, y, λ) obtained through a Sagnac interferometer under uniform illumination and structured illumination, spectrally resolved images with depth resolution can be recovered using structured light illumination algorithms such as the HiLo method. The proposed scheme is validated with in vitro specimens including fluorescent solution and fluorescent beads with known spectra. The system is further demonstrated in quantifying spectra from 3D resolved features in biological specimens. The system has demonstrated depth resolution of 1.8 μm and spectral resolution of 7 nm respectively. PMID:25360367

  7. Magnetic Cycles and Buoyant Loops in Convective Dynamos

    NASA Astrophysics Data System (ADS)

    Nelson, Nicholas J.

    2013-01-01

    Solar-type stars display a rich spectrum of magnetic activity. Seeking to explore convective dynamo action in solar-like stars with the anelastic spherical harmonic (ASH) code, we have carried out a series of global 3-D MHD simulations. Here we report on the dynamo mechanisms realized in a series of numerical models of a sun-like star which explore the effects of decreasing diffusion. While these models nominally rotate at three times the current solar rate (3Ω), the results may be more widely applicable as both these simulations and the solar convection zone achieve similar levels of rotationally constrained convection. Previous simulations at 3Ω have shown that convective dynamos can build persistent wreath-like structures of strong toroidal magnetic field in the convection zone (Brown et al. 2010). Here we find that magnetic reversals and cycles can be realized at 3Ω by decreasing the explicit diffusion and thereby making the resolved flows more turbulent. In these more turbulent models, diffusive processes no longer play a primary role in the key dynamical balances which maintain differential rotation and generate the global-scale wreaths. With reduced resistive diffusion of magnetic fields, the axisymmetric poloidal fields can no longer achieve a steady state and this triggers reversals in global magnetic polarity. Additionally, the enhanced levels of turbulence lead to greater intermittency in the toroidal magnetic wreaths, which can create buoyant magnetic loops that rise from the deep interior to the upper regions of our simulated domain. Turbulence-enabled magnetic buoyancy in our most turbulent simulation yields large numbers of buoyant loops, enabling us to examine the distribution of the characteristics of buoyant magnetic loops, such as twist, tilt angle, and relation to axisymmetric fields. These models provide a pathway towards linking convective dynamo models and the emergence of magnetic flux in the Sun and sun-like stars.

  8. A discrete analog of the extended Bass algorithm for stabilizing constant linear systems

    NASA Technical Reports Server (NTRS)

    Armstrong, E. S.; Rublein, G. T.

    1976-01-01

    Two methods for stabilizing constant linear systems, namely, the extended Bass algorithm for continuous systems and a discrete system analog, are discussed. For the continuous algorithm, a new result on the degree of stability of the closed-loop eigenvalues is presented, and for both methods, typical results and asymptotic trends in the data are illustrated through an example computation.

  9. Loop calculus for lattice gauge theories

    SciTech Connect

    Gambini, R.; Leal, L.; Trias, A.

    1989-05-15

    Hamiltonian calculations are performed using a loop-labeled basis where the full set of identities for the SU(/ital N/) gauge models has been incorporated. The loops are classified as clusterlike structures and the eigenvalue problem leads to a linear set of finite-difference equations easily amenable to numerical treatment. Encouraging results are reported for SU(2) at spatial dimension 2.

  10. Feedback loop compensates for rectifier nonlinearity

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Signal processing circuit with two negative feedback loops rectifies two sinusoidal signals which are 180 degrees out of phase and produces a single full-wave rectified output signal. Each feedback loop incorporates a feedback rectifier to compensate for the nonlinearity of the circuit.

  11. The Cygnus Loop: An Older Supernova Remnant.

    ERIC Educational Resources Information Center

    Straka, William

    1987-01-01

    Describes the Cygnus Loop, one of brightest and most easily studied of the older "remnant nebulae" of supernova outbursts. Discusses some of the historical events surrounding the discovery and measurement of the Cygnus Loop and makes some projections on its future. (TW)

  12. Structural Study of a Flexible Active Site Loop in Human Indoleamine 2,3-Dioxygenase and Its Functional Implications.

    PubMed

    Álvarez, Lucía; Lewis-Ballester, Ariel; Roitberg, Adrián; Estrin, Darío A; Yeh, Syun-Ru; Marti, Marcelo A; Capece, Luciana

    2016-05-17

    Human indoleamine 2,3-dioxygenase catalyzes the oxidative cleavage of tryptophan to N-formyl kynurenine, the initial and rate-limiting step in the kynurenine pathway. Additionally, this enzyme has been identified as a possible target for cancer therapy. A 20-amino acid protein segment (the JK loop), which connects the J and K helices, was not resolved in the reported hIDO crystal structure. Previous studies have shown that this loop undergoes structural rearrangement upon substrate binding. In this work, we apply a combination of replica exchange molecular dynamics simulations and site-directed mutagenesis experiments to characterize the structure and dynamics of this protein region. Our simulations show that the JK loop can be divided into two regions: the first region (JK loop(C)) displays specific and well-defined conformations and is within hydrogen bonding distance of the substrate, while the second region (JK loop(N)) is highly disordered and exposed to the solvent. The peculiar flexible nature of JK loop(N) suggests that it may function as a target for post-translational modifications and/or a mediator for protein-protein interactions. In contrast, hydrogen bonding interactions are observed between the substrate and Thr379 in the highly conserved "GTGG" motif of JK loop(C), thereby anchoring JK loop(C) in a closed conformation, which secures the appropriate substrate binding mode for catalysis. Site-directed mutagenesis experiments confirm the key role of this residue, highlighting the importance of the JK loop(C) conformation in regulating the enzymatic activity. Furthermore, the existence of the partially and totally open conformations in the substrate-free form suggests a role of JK loop(C) in controlling substrate and product dynamics. PMID:27112409

  13. Piloted simulation of an on-board trajectory optimization algorithm

    NASA Technical Reports Server (NTRS)

    Price, D. B.; Calise, A. J.; Moerder, D. D.

    1981-01-01

    This paper will describe a real time piloted simulation of algorithms designed for on-board computation of time-optimal intercept trajectories for an F-8 aircraft. The algorithms, which were derived using singular perturbation theory, generate commands that are displayed to the pilot on flight director needles on the 8-ball. By flying the airplane so as to zero the horizontal and vertical needles, the pilot flies an approximation to a time-optimal intercept trajectory. The various display and computation modes that are available will be described and results will be presented illustrating the performance of the algorithms with a pilot in the loop.

  14. Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes

    PubMed Central

    Szczelkun, Mark D.; Tikhomirova, Maria S.; Sinkunas, Tomas; Gasiunas, Giedrius; Karvelis, Tautvydas; Pschera, Patrizia; Siksnys, Virginijus; Seidel, Ralf

    2014-01-01

    Clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems protect bacteria and archaea from infection by viruses and plasmids. Central to this defense is a ribonucleoprotein complex that produces RNA-guided cleavage of foreign nucleic acids. In DNA-targeting CRISPR-Cas systems, the RNA component of the complex encodes target recognition by forming a site-specific hybrid (R-loop) with its complement (protospacer) on an invading DNA while displacing the noncomplementary strand. Subsequently, the R-loop structure triggers DNA degradation. Although these reactions have been reconstituted, the exact mechanism of R-loop formation has not been fully resolved. Here, we use single-molecule DNA supercoiling to directly observe and quantify the dynamics of torque-dependent R-loop formation and dissociation for both Cascade- and Cas9-based CRISPR-Cas systems. We find that the protospacer adjacent motif (PAM) affects primarily the R-loop association rates, whereas protospacer elements distal to the PAM affect primarily R-loop stability. Furthermore, Cascade has higher torque stability than Cas9 by using a conformational locking step. Our data provide direct evidence for directional R-loop formation, starting from PAM recognition and expanding toward the distal protospacer end. Moreover, we introduce DNA supercoiling as a quantitative tool to explore the sequence requirements and promiscuities of orthogonal CRISPR-Cas systems in rapidly emerging gene-targeting applications. PMID:24912165

  15. Loop polymer brushes from polymer single crystals

    NASA Astrophysics Data System (ADS)

    Zhou, Tian; Li, Christopher

    2014-03-01

    Loop polymer brushes represent a category of polymer brushes with both chain ends being tethered to a surface or interface with sufficiently high density. Due to this morphological difference, loop brushes exhibit distinct properties compared with traditional polymer brushes with single chain end being tethered. In our study, α, ω-functionalized polycaprolactone (PCL) single crystals were prepared as templates for polymer brush synthesis. By carefully controlling crystallization condition and immobilization, looped polymer brushes were successfully prepared. Comprehensive studies on the morphology and physical properties of these polymer brushes were carried out using Atomic Force Microscopy and FTIR. Advantages of using this method include exclusive loop morphology, high grafting density, controlled tethering sites and tunable loop size.

  16. Library of Continuation Algorithms

    2005-03-01

    LOCA (Library of Continuation Algorithms) is scientific software written in C++ that provides advanced analysis tools for nonlinear systems. In particular, it provides parameter continuation algorithms. bifurcation tracking algorithms, and drivers for linear stability analysis. The algorithms are aimed at large-scale applications that use Newton’s method for their nonlinear solve.

  17. Transient brightenings of interconnecting loops. II - Dynamics of the brightened loops

    NASA Technical Reports Server (NTRS)

    Svestka, Z.; Howard, R.

    1981-01-01

    Three different kinds of dynamic events related to interconnecting loops observed in soft X-rays aboard Skylab are discussed: (1) a newly born transequatorial loop that was either emerging from subphotospheric layers or gradually filled in with hot plasma; (2) large-scale twists of interconnecting loops which never relax, and often only form after the loop brightenings, and (3) three events where the loop that later interconnected two active regions had been visible long before one of the interconnecting regions was born. Several impacts this observation might have upon the understanding of the process of flux emergence are suggested.

  18. A communication scheme for the distrubted execution of loop nests with while loops

    SciTech Connect

    Griebl, M.; Lengauer, C.

    1995-10-01

    The mathematical model for the parallelization, or {open_quotes}space-time mapping,{close_quotes} of loop nests is the polyhedron model. The presence of while loops in the nest complicates matters for two reasons: (1) the parallelized loop nest does not correspond to a polyhedron but instead to a subset that resembles a (multi-dimensional) comb and (2) it is not clear when the entire loop nest has terminated. We describe a communication scheme which can deal with both problems and which can be added to the parallel target loop nest by a compiler.

  19. Loop heat pipes and capillary pumped loops-an applications perspective

    NASA Astrophysics Data System (ADS)

    Butler, Dan; Ku, Jentung; Swanson, Theodore

    2002-01-01

    Capillary pumped loops (CPLs) and loop heat pipes (LHPs) are versatile two-phase heat transfer devices which have recently gained increasing acceptance in space applications. Both systems work based on the same principles and have very similar designs. Nevertheless, some differences exist in the construction of the evaporator and the hydro-accumulator, and these differences lead to very distinct operating characteristics for each loop. This paper presents comparisons of the two loops from an applications perspective, and addresses their impact on spacecraft design, integration, and test. Some technical challenges and issues for both loops are also addressed. .

  20. The BR eigenvalue algorithm

    SciTech Connect

    Geist, G.A.; Howell, G.W.; Watkins, D.S.

    1997-11-01

    The BR algorithm, a new method for calculating the eigenvalues of an upper Hessenberg matrix, is introduced. It is a bulge-chasing algorithm like the QR algorithm, but, unlike the QR algorithm, it is well adapted to computing the eigenvalues of the narrowband, nearly tridiagonal matrices generated by the look-ahead Lanczos process. This paper describes the BR algorithm and gives numerical evidence that it works well in conjunction with the Lanczos process. On the biggest problems run so far, the BR algorithm beats the QR algorithm by a factor of 30--60 in computing time and a factor of over 100 in matrix storage space.

  1. Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells

    PubMed Central

    Priest, David G.; Kumar, Sandip; Yan, Yan; Dunlap, David D.; Dodd, Ian B.; Shearwin, Keith E.

    2014-01-01

    Eukaryotic gene regulation involves complex patterns of long-range DNA-looping interactions between enhancers and promoters, but how these specific interactions are achieved is poorly understood. Models that posit other DNA loops—that aid or inhibit enhancer–promoter contact—are difficult to test or quantitate rigorously in eukaryotic cells. Here, we use the well-characterized DNA-looping proteins Lac repressor and phage λ CI to measure interactions between pairs of long DNA loops in E. coli cells in the three possible topological arrangements. We find that side-by-side loops do not affect each other. Nested loops assist each other’s formation consistent with their distance-shortening effect. In contrast, alternating loops, where one looping element is placed within the other DNA loop, inhibit each other’s formation, thus providing clear support for the loop domain model for insulation. Modeling shows that combining loop assistance and loop interference can provide strong specificity in long-range interactions. PMID:25288735

  2. Four-phase differential phase shift resolver

    NASA Technical Reports Server (NTRS)

    Hopkins, P. M.; Wallingford, W. M.

    1973-01-01

    Two systems have been developed to resolve phase uncertainty without transmitting reference signals. In both methods signal is impressed on carrier as differential, rather than absolute, phase shift. At the receiver four-phase demodulation and logic process unambiguously resolves differential phase shift of input carrier.

  3. Helping You Buy: Link Resolver Tools

    ERIC Educational Resources Information Center

    Singer, Ross

    2006-01-01

    To any library with an electronic collection of any significance, the OpenURL link resolver has (or should) become an indispensable service for helping its users retrieve full text from citations. Although they are a relatively new technology (in library terms, at any rate), link resolvers arguably have become as important as the OPAC; they locate…

  4. Time-resolved X-ray PIV measurements of hemodynamic information of real pulsatile blood flows

    NASA Astrophysics Data System (ADS)

    Park, Hanwook; Yeom, Eunseop; Lee, Sang Joon

    2015-11-01

    X-ray imaging technique has been used to visualize various bio-fluid flow phenomena as a nondestructive manner. To obtain hemodynamic information related with circulatory vascular diseases, a time-resolved X-ray PIV technique with high temporal resolution was developed. In this study, to embody actual pulsatile blood flows in a circular conduit without changes in hemorheological properties, a bypass loop is established by connecting a microtube between the jugular vein and femoral artery of a rat. Biocompatible CO2 microbubbles are used as tracer particles. After mixing with whole blood, CO2 microbubbles are injected into the bypass loop. Particle images of the pulsatile blood flows in the bypass loop are consecutively captured by the time-resolved X-ray PIV system. The velocity field information are obtained with varying flow rate and pulsataility. To verify the feasibility of the use of CO2 microbubbles under in vivo conditions, the effects of the surrounding-tissues are also investigated, because these effects are crucial for deteriorating the image contrast of CO2 microbubbles. Therefore, the velocity information of blood flows in the abdominal aorta are obtained to demonstrate the visibility and usefulness of CO2 microbubbles under ex vivo conditions. This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2008-0061991).

  5. Towards conformal loop quantum gravity

    NASA Astrophysics Data System (ADS)

    H-T Wang, Charles

    2006-03-01

    A discussion is given of recent developments in canonical gravity that assimilates the conformal analysis of gravitational degrees of freedom. The work is motivated by the problem of time in quantum gravity and is carried out at the metric and the triad levels. At the metric level, it is shown that by extending the Arnowitt-Deser-Misner (ADM) phase space of general relativity (GR), a conformal form of geometrodynamics can be constructed. In addition to the Hamiltonian and Diffeomorphism constraints, an extra first class constraint is introduced to generate conformal transformations. This phase space consists of York's mean extrinsic curvature time, conformal three-metric and their momenta. At the triad level, the phase space of GR is further enlarged by incorporating spin-gauge as well as conformal symmetries. This leads to a canonical formulation of GR using a new set of real spin connection variables. The resulting gravitational constraints are first class, consisting of the Hamiltonian constraint and the canonical generators for spin-gauge and conformorphism transformations. The formulation has a remarkable feature of being parameter-free. Indeed, it is shown that a conformal parameter of the Barbero-Immirzi type can be absorbed by the conformal symmetry of the extended phase space. This gives rise to an alternative approach to loop quantum gravity that addresses both the conceptual problem of time and the technical problem of functional calculus in quantum gravity.

  6. Direct Demonstration That Loop1 of Scap Binds to Loop7: A CRUCIAL EVENT IN CHOLESTEROL HOMEOSTASIS.

    PubMed

    Zhang, Yinxin; Lee, Kwang Min; Kinch, Lisa N; Clark, Lindsay; Grishin, Nick V; Rosenbaum, Daniel M; Brown, Michael S; Goldstein, Joseph L; Radhakrishnan, Arun

    2016-06-10

    Cholesterol homeostasis is mediated by Scap, a polytopic endoplasmic reticulum (ER) protein that transports sterol regulatory element-binding proteins from the ER to Golgi, where they are processed to forms that activate cholesterol synthesis. Scap has eight transmembrane helices and two large luminal loops, designated Loop1 and Loop7. We earlier provided indirect evidence that Loop1 binds to Loop7, allowing Scap to bind COPII proteins for transport in coated vesicles. When ER cholesterol rises, it binds to Loop1. We hypothesized that this causes dissociation from Loop7, abrogating COPII binding. Here we demonstrate direct binding of the two loops when expressed as isolated fragments or as a fusion protein. Expressed alone, Loop1 remained intracellular and membrane-bound. When Loop7 was co-expressed, it bound to Loop1, and the soluble complex was secreted. A Loop1-Loop7 fusion protein was also secreted, and the two loops remained bound when the linker between them was cleaved by a protease. Point mutations that disrupt the Loop1-Loop7 interaction prevented secretion of the Loop1-Loop7 fusion protein. These data provide direct documentation of intramolecular Loop1-Loop7 binding, a central event in cholesterol homeostasis. PMID:27068746

  7. Sequential Closure of Loop Structures Forms the Folding Nucleus during the Refolding Transition of the Escherichia coli Adenylate Kinase Molecule.

    PubMed

    Orevi, Tomer; Rahamim, Gil; Amir, Dan; Kathuria, Sagar; Bilsel, Osman; Matthews, C Robert; Haas, Elisha

    2016-01-12

    The ensemble of conformers of globular protein molecules immediately following transfer from unfolding to folding conditions is assumed to be collapsed though still disordered, as the first steps of the folding pathway are initiated. In order to test the hypothesis that long loop closure transitions are part of the initiation of the folding pathway, our groups are studying the initiation of the folding transition of a model protein by time-resolved excitation energy transfer (trFRET) detected fast kinetics experiments. Site-specific double labeling is used to study the timing of conformational transitions of individual loop forming chain segments at the microsecond time regime. Previously, it was shown that at least three long loops in the Escherichia coli adenylate kinase (AK) molecule close within the first 5 ms of folding of AK, while the main global folding transition occurs in a time regime of seconds. In order to enhance the time resolution of the kinetics experiments to the microsecond time regime and determine the rate of closure of the two N terminal loops (loop I residues 1-26 and loop II residues 29-72), we applied a continuous flow based double kinetics experiment. These measurements enabled us to obtain a microsecond series of transient time dependent distributions of distances between the ends of the labeled loops. Analysis of the trFRET experiments show that the N terminal loop (loop I) is closed within less than 60 μs after the initiation of refolding. Loop II is also mostly closed within that time step but shows an additional small reduction of the mean end-to-end distance in a second phase at a rate of 0.005 μs(-1). This second phase can either reflect tightening of a loosely closed loop in the ensemble of conformers or may reflect two subpopulations in the ensemble, which differ in the rate of closure of loop II, but not in the rate of closure of loop I. This study shows the very fast closure of long loops in the otherwise disordered backbone

  8. A closed-loop photon beam control study for the Advanced Light Source

    SciTech Connect

    Portmann, G.; Bengtsson, J.

    1993-05-01

    The third generation Advanced Light Source (ALS) will produce extremely bright photon beams using undulators and wigglers. In order to position the photon beams accurate to the micron level, a closed-loop feedback system is being developed. Using photon position monitors and dipole corrector magnets, a closed-loop system can automatically compensate for modeling uncertainties and exogenous disturbances. The following paper will present a dynamics model for the perturbations of the closed orbit of the electron beam in the ALS storage ring including the vacuum chamber magnetic field penetration effects. Using this reference model, two closed-loop feedback algorithms will be compared -- a classical PI controller and a two degree-of-freedom approach. The two degree-of-freedom method provides superior disturbance rejection while maintaining the desired performance goals. Both methods will address the need to gain schedule the controller due to the time varying dynamics introduced by changing field strengths when scanning the insertion devices.

  9. Closed-Loop Artificial Pancreas Systems: Physiological Input to Enhance Next-Generation Devices

    PubMed Central

    Kudva, Yogish C.; Carter, Rickey E.; Cobelli, Claudio

    2014-01-01

    To provide an understanding of both the preclinical and clinical aspects of closed-loop artificial pancreas systems, we provide a discussion of this topic as part of this two-part Bench to Clinic narrative. Here, the Bench narrative provides an in-depth understanding of insulin-glucose-glucagon physiology in conditions that mimic the free-living situation to the extent possible in type 1 diabetes that will help refine and improve future closed-loop system algorithms. In the Clinic narrative, Doyle and colleagues compare and evaluate technology used in current closed-loop studies to gain further momentum toward outpatient trials and eventual approval for widespread use. PMID:24757225

  10. Counting loop diagrams: computational complexity of higher-order amplitude evaluation

    NASA Astrophysics Data System (ADS)

    van Eijk, E.; Kleiss, R.; Lazopoulos, A.

    2004-08-01

    We discuss the computational complexity of the perturbative evaluation of scattering amplitudes, both by the Caravaglios-Moretti algorithm and by direct evaluation of the individual diagrams. For a self-interacting scalar theory, we determine the complexity as a function of the number of external legs. We describe a method for obtaining the number of topologically inequivalent Feynman graphs containing closed loops, and apply this to 1- and 2-loop amplitudes. We also compute the number of graphs weighted by their symmetry factors, thus arriving at exact and asymptotic estimates for the average symmetry factor of diagrams. We present results for the asymptotic number of diagrams up to 10 loops, and prove that the average symmetry factor approaches unity as the number of external legs becomes large.

  11. [Closed-loop control for chest compression based on coronary perfusion pressure: a computer simulation study].

    PubMed

    Chen, Aihua; Gao, Lei; Tian, Linhuai; Zhang, Jian; Zhan, Ningbo

    2014-08-01

    In this study, a closed-loop controller for chest compression which adjusts chest compression depth according to the coronary perfusion pressure (CPP) was proposed. An effective and personalized chest compression method for automatic mechanical compression devices was provided, and the traditional and uniform chest compression standard neglecting individual difference was improved. This study rebuilds Charles F. Babbs human circulation model with CPP simulation module and proposes a closed-loop controller based on a fuzzy control algorithm. The performance of the fuzzy controller was evaluated and compared to that of a traditional PID controller in computer simulation studies. The simulation results demonstrated that the fuzzy closed-loop controller produced shorter regulation time, fewer oscillations and smaller overshoot than those of the traditional PID controller and outperforms the traditional PID controller in CPP regulation and maintenance. PMID:25464812

  12. [Closed-loop control for chest compression based on coronary perfusion pressure: a computer simulation study].

    PubMed

    Chen, Aihua; Gao, Lei; Tian, Linhuai; Zhang, Jian; Zhan, Ningbo

    2014-08-01

    In this study, a closed-loop controller for chest compression which adjusts chest compression depth according to the coronary perfusion pressure (CPP) was proposed. An effective and personalized chest compression method for automatic mechanical compression devices was provided, and the traditional and uniform chest compression standard neglecting individual difference was improved. This study rebuilds Charles F. Babbs human circulation model with CPP simulation module and proposes a closed-loop controller based on a fuzzy control algorithm. The performance of the fuzzy controller was evaluated and compared to that of a traditional PID controller in computer simulation studies. The simulation results demonstrated that the fuzzy closed-loop controller produced shorter regulation time, fewer oscillations and smaller overshoot than those of the traditional PID controller and outperforms the traditional PID controller in CPP regulation and maintenance. PMID:25508443

  13. Linear state feedback, quadratic weights, and closed loop eigenstructures. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Thompson, P. M.

    1979-01-01

    Results are given on the relationships between closed loop eigenstructures, state feedback gain matrices of the linear state feedback problem, and quadratic weights of the linear quadratic regulator. Equations are derived for the angles of general multivariable root loci and linear quadratic optimal root loci, including angles of departure and approach. The generalized eigenvalue problem is used for the first time to compute angles of approach. Equations are also derived to find the sensitivity of closed loop eigenvalues and the directional derivatives of closed loop eigenvectors (with respect to a scalar multiplying the feedback gain matrix or the quadratic control weight). An equivalence class of quadratic weights that produce the same asymptotic eigenstructure is defined, sufficient conditions to be in it are given, a canonical element is defined, and an algorithm to find it is given. The behavior of the optimal root locus in the nonasymptotic region is shown to be different for quadratic weights with the same asymptotic properties.

  14. Multispectral excitation based multiple fluorescent targets resolving in fluorescence molecular tomography

    NASA Astrophysics Data System (ADS)

    Zhou, Yuan; Guang, Huizhi; Pu, Huangsheng; Zhang, Jiulou; Bai, Jing; Luo, Jianwen

    2016-04-01

    Fluorescence molecular tomography (FMT) can visualize biological activities at cellular and molecular levels in vivo, and has been extensively used in drug delivery and tumor detection research of small animals. The ill-posedness of the FMT inverse problem makes it difficult to reconstruct and resolve multiple adjacent fluorescent targets that have different functional features but are labeled with the same fluorochrome. An algorithm based on independent component analysis (ICA) for multispectral excited FMT is proposed to resolve multiple fluorescent targets in this study. Fluorescent targets are excited by multispectral excitation, and the three-dimensional distribution of fluorescent yields under the excitation spectrum is reconstructed by an iterative Tikhonov regularization algorithm. Subsequently, multiple fluorescent targets are resolved from mixed fluorescence signals by employing ICA. Simulations were performed and the results demonstrate that multiple adjacent fluorescent targets can be resolved if the number of excitation wavelengths is not smaller than that of fluorescent targets with different concentrations. The algorithm obtains both independent components that provide spatial information of different fluorescent targets and spectral courses that reflect variation trends of fluorescent yields along with the excitation spectrum. By using this method, it is possible to visualize the metabolism status of drugs in different structure organs, and quantitatively depict the variation trends of fluorescent yields of each functional organ under the excitation spectrum. This method may provide a pattern for tumor detection, drug delivery and treatment monitoring in vivo.

  15. Super-resolved parallel MRI by spatiotemporal encoding.

    PubMed

    Schmidt, Rita; Baishya, Bikash; Ben-Eliezer, Noam; Seginer, Amir; Frydman, Lucio

    2014-01-01

    Recent studies described an "ultrafast" scanning method based on spatiotemporal (SPEN) principles. SPEN demonstrates numerous potential advantages over EPI-based alternatives, at no additional expense in experimental complexity. An important aspect that SPEN still needs to achieve for providing a competitive ultrafast MRI acquisition alternative, entails exploiting parallel imaging algorithms without compromising its proven capabilities. The present work introduces a combination of multi-band frequency-swept pulses simultaneously encoding multiple, partial fields-of-view, together with a new algorithm merging a Super-Resolved SPEN image reconstruction and SENSE multiple-receiving methods. This approach enables one to reduce both the excitation and acquisition times of sub-second SPEN acquisitions by the customary acceleration factor R, without compromises in either the method's spatial resolution, SAR deposition, or capability to operate in multi-slice mode. The performance of these new single-shot imaging sequences and their ancillary algorithms were explored and corroborated on phantoms and human volunteers at 3 T. The gains of the parallelized approach were particularly evident when dealing with heterogeneous systems subject to major T2/T2* effects, as is the case upon single-scan imaging near tissue/air interfaces. PMID:24120293

  16. Mitotic chromosome compaction via active loop extrusion

    NASA Astrophysics Data System (ADS)

    Goloborodko, Anton; Imakaev, Maxim; Marko, John; Mirny, Leonid; MIT-Northwestern Team

    During cell division, two copies of each chromosome are segregated from each other and compacted more than hundred-fold into the canonical X-shaped structures. According to earlier microscopic observations and the recent Hi-C study, chromosomes are compacted into arrays of consecutive loops of ~100 kilobases. Mechanisms that lead to formation of such loop arrays are largely unknown. Here we propose that, during cell division, chromosomes can be compacted by enzymes that extrude loops on chromatin fibers. First, we use computer simulations and analytical modeling to show that a system of loop-extruding enzymes on a chromatin fiber self-organizes into an array of consecutive dynamic loops. Second, we model the process of loop extrusion in 3D and show that, coupled with the topo II strand-passing activity, it leads to robust compaction and segregation of sister chromatids. This mechanism of chromosomal condensation and segregation does not require additional proteins or specific DNA markup and is robust against variations in the number and properties of such loop extruding enzymes. Work at NU was supported by the NSF through Grants DMR-1206868 and MCB-1022117, and by the NIH through Grants GM105847 and CA193419. Work at MIT was supported by the NIH through Grants GM114190 R01HG003143.

  17. Near-Native Protein Loop Sampling Using Nonparametric Density Estimation Accommodating Sparcity

    PubMed Central

    Day, Ryan; Lennox, Kristin P.; Sukhanov, Paul; Dahl, David B.; Vannucci, Marina; Tsai, Jerry

    2011-01-01

    Unlike the core structural elements of a protein like regular secondary structure, template based modeling (TBM) has difficulty with loop regions due to their variability in sequence and structure as well as the sparse sampling from a limited number of homologous templates. We present a novel, knowledge-based method for loop sampling that leverages homologous torsion angle information to estimate a continuous joint backbone dihedral angle density at each loop position. The φ,ψ distributions are estimated via a Dirichlet process mixture of hidden Markov models (DPM-HMM). Models are quickly generated based on samples from these distributions and were enriched using an end-to-end distance filter. The performance of the DPM-HMM method was evaluated against a diverse test set in a leave-one-out approach. Candidates as low as 0.45 Å RMSD and with a worst case of 3.66 Å were produced. For the canonical loops like the immunoglobulin complementarity-determining regions (mean RMSD <2.0 Å), the DPM-HMM method performs as well or better than the best templates, demonstrating that our automated method recaptures these canonical loops without inclusion of any IgG specific terms or manual intervention. In cases with poor or few good templates (mean RMSD >7.0 Å), this sampling method produces a population of loop structures to around 3.66 Å for loops up to 17 residues. In a direct test of sampling to the Loopy algorithm, our method demonstrates the ability to sample nearer native structures for both the canonical CDRH1 and non-canonical CDRH3 loops. Lastly, in the realistic test conditions of the CASP9 experiment, successful application of DPM-HMM for 90 loops from 45 TBM targets shows the general applicability of our sampling method in loop modeling problem. These results demonstrate that our DPM-HMM produces an advantage by consistently sampling near native loop structure. The software used in this analysis is available for download at http

  18. Resolved rate and torque control schemes for large scale space based kinematically redundant manipulators

    NASA Technical Reports Server (NTRS)

    Bailey, Robert W.; Quiocho, Leslie J.

    1991-01-01

    Resolved rate control of kinematically redundant ground based manipulators is a challenging problem. The structural, actuator, and control loop frequency characteristics of industrial grade robots generally allow operation with resolved rate control; a rate command is achievable with good accuracy. However, space based manipulators are different, typically have less structural stiffness, more motor and joint friction, and lower control loop cycle frequencies. These undesirable characteristics present a considerable Point of Resolution (POR) control problem for space based, kinematically redundant manipulators for the following reason: a kinematically redundant manipulator requires an arbitrary constraint to solve for the joint rate commands. A space manipulator will not respond to joint rate commands because of these characteristics. A space based manipulator simulation, including free end rigid body dynamics, motor dynamics, motor striction/friction, gearbox backlash, joint striction/friction, and Space Station Remote Manipulator System type configuration parameters, is used to evaluate the performance of a documented resolved rate control law. Alternate schemes which include torque control are also evaluated.

  19. Closed loop control of dielectric elastomer actuators based on self-sensing displacement feedback

    NASA Astrophysics Data System (ADS)

    Rizzello, G.; Naso, D.; York, A.; Seelecke, S.

    2016-03-01

    This paper describes a sensorless control algorithm for a positioning system based on a dielectric elastomer actuator (DEA). The voltage applied to the membrane and the resulting current can be measured during the actuation and used to estimate its displacement, i.e., to perform self-sensing. The estimated displacement can be then used as a feedback signal for a position control algorithm, which results in a compact device capable of operating in closed loop control without the need for additional electromechanical or optical transducers. In this work, a circular DEA preloaded with a bi-stable spring is used as a case of study to validate the proposed control architecture. A comparison of the closed loop performance achieved using an accurate laser displacement sensor for feedback is also provided to better assess the performance limitations of the overall sensorless scheme.

  20. Hardware-in-the-loop simulation and energy optimization of cardiac pacemakers.

    PubMed

    Barker, Chris; Kwiatkowska, Marta; Mereacre, Alexandru; Paoletti, Nicola; Patane, Andrea

    2015-08-01

    Implantable cardiac pacemakers are medical devices that can monitor and correct abnormal heart rhythms. To provide the necessary safety assurance for pacemaker software, both testing and verification of the code, as well as testing the entire pacemaker hardware in the loop, is necessary. In this paper, we present a hardware testbed that enables detailed hardware-in-the-loop simulation and energy optimisation of pacemaker algorithms with respect to a heart model. Both the heart and the pacemaker models are encoded in Simulink/Stateflow™ and translated into executable code, with the pacemaker executed directly on the microcontroller. We evaluate the usefulness of the testbed by developing a parameter synthesis algorithm which optimises the timing parameters based on power measurements acquired in real-time. The experiments performed on real measurements successfully demonstrate that the testbed is capable of energy minimisation in real-time and obtains safe pacemaker timing parameters. PMID:26737950

  1. Closed-loop and decision-assist resuscitation of burn patients.

    PubMed

    Salinas, Jose; Drew, Guy; Gallagher, James; Cancio, Leopoldo C; Wolf, Steven E; Wade, Charles E; Holcomb, John B; Herndon, David N; Kramer, George C

    2008-04-01

    Effective resuscitation is critical in reducing mortality and morbidity rates of patients with acute burns. To this end, guidelines and formulas have been developed to define infusion rates and volume requirements during the first 48 hours postburn. Even with these standardized resuscitation guidelines, however, over- and under-resuscitation are not uncommon. Two approaches to adjust infusion rate are decision-assist and closed-loop algorithms based on levels of urinary output. Specific decision assist guidelines or a closed-loop system using computer-controlled feedback technology that supplies automatic control of infusion rates can potentially achieve better control of urinary output. In a properly designed system, closed-loop control has the potential to provide more accurate titration rates, while lowering the incidence of over- and under-resuscitation. Because the system can self-adjust based on monitoring inputs, the technology can be pushed to environments such as combat zones where burn resuscitation expertise is limited. A closed-loop system can also assist in the management of mass casualties, another scenario in which medical expertise is often in short supply. This article reviews the record of fluid balance of contemporary burn resuscitation and approaches, as well as the engineering efforts, animal studies, and algorithm development of our most recent autonomous systems for burn resuscitation. PMID:18385584

  2. The ionospheric outflow feedback loop

    NASA Astrophysics Data System (ADS)

    Moore, T. E.; Fok, M.-C.; Garcia-Sage, K.

    2014-08-01

    Following a long period of observation and investigation beginning in the early 1970s, it has been firmly established that Earth's magnetosphere is defined as much by the geogenic plasma within it as by the geomagnetic field. This plasma is not confined to the ionosphere proper, defined as the region within a few density scale heights of the F-region plasma density peak. Rather, it fills the flux tubes on which it is created, and circulates throughout the magnetosphere in a pattern driven by solar wind plasma that becomes magnetically connected to the ionosphere by reconnection through the dayside magnetopause. Under certain solar wind conditions, plasma and field energy is stored in the magnetotail rather than being smoothly recirculated back to the dayside. Its release into the downstream solar wind is produced by magnetotail disconnection of stored plasma and fields both continuously and in the form of discrete plasmoids, with associated generation of energetic Earthward-moving bursty bulk flows and injection fronts. A new generation of global circulation models is showing us that outflowing ionospheric plasmas, especially O+, load the system in a different way than the resistive F-region load of currents dissipating energy in the plasma and atmospheric neutral gas. The extended ionospheric load is reactive to the primary dissipation, forming a time-delayed feedback loop within the system. That sets up or intensifies bursty transient behaviors that would be weaker or absent if the ionosphere did not “strike back” when stimulated. Understanding this response appears to be a necessary, if not sufficient, condition for us to gain accurate predictive capability for space weather. However, full predictive understanding of outflow and incorporation into global simulations requires a clear observational and theoretical identification of the causal mechanisms of the outflows. This remains elusive and requires a dedicated mission effort.

  3. NASA MSFC hardware in the loop simulations of automatic rendezvous and capture systems

    NASA Technical Reports Server (NTRS)

    Tobbe, Patrick A.; Naumann, Charles B.; Sutton, William; Bryan, Thomas C.

    1991-01-01

    Two complementary hardware-in-the-loop simulation facilities for automatic rendezvous and capture systems at MSFC are described. One, the Flight Robotics Laboratory, uses an 8 DOF overhead manipulator with a work volume of 160 by 40 by 23 feet to evaluate automatic rendezvous algorithms and range/rate sensing systems. The other, the Space Station/Station Operations Mechanism Test Bed, uses a 6 DOF hydraulic table to perform docking and berthing dynamics simulations.

  4. Implementation of a Vector-based Tracking Loop Receiver in a Pseudolite Navigation System

    PubMed Central

    So, Hyoungmin; Lee, Taikjin; Jeon, Sanghoon; Kim, Chongwon; Kee, Changdon; Kim, Taehee; Lee, Sanguk

    2010-01-01

    We propose a vector tracking loop (VTL) algorithm for an asynchronous pseudolite navigation system. It was implemented in a software receiver and experiments in an indoor navigation system were conducted. Test results show that the VTL successfully tracks signals against the near–far problem, one of the major limitations in pseudolite navigation systems, and could improve positioning availability by extending pseudolite navigation coverage. PMID:22163552

  5. Closed-Loop Rehabilitation of Age-Related Cognitive Disorders

    PubMed Central

    Mishra, Jyoti; Gazzaley, Adam

    2015-01-01

    Cognitive deficits are common in older adults, as a result of both the natural aging process and neurodegenerative disease. Although medical advancements have successfully prolonged the human lifespan, the challenge of remediating cognitive aging remains. The authors discuss the current state of cognitive therapeutic interventions and then present the need for development and validation of more powerful neurocognitive therapeutics. They propose that the next generation of interventions be implemented as closed-loop systems that target specific neural processing deficits, incorporate quantitative feedback to the individual and clinician, and are personalized to the individual’s neurocognitive capacities using real-time performance-adaptive algorithms. This approach should be multimodal and seamlessly integrate other treatment approaches, including neurofeedback and transcranial electrical stimulation. This novel approach will involve the generation of software that engages the individual in an immersive and enjoyable game-based interface, integrated with advanced biosensing hardware, to maximally harness plasticity and assure adherence. Introducing such next-generation closed-loop neurocognitive therapeutics into the mainstream of our mental health care system will require the combined efforts of clinicians, neuroscientists, bioengineers, software game developers, and industry and policy makers working together to meet the challenges and opportunities of translational neuroscience in the 21st century. PMID:25520029

  6. Sensor enabled closed-loop bending control of soft beams

    NASA Astrophysics Data System (ADS)

    Case, Jennifer C.; White, Edward L.; Kramer, Rebecca K.

    2016-04-01

    Control of soft-bodied systems is challenging, as the absence of rigidity typically implies distributed deformations and infinite degrees-of-freedom. In this paper, we demonstrate closed-loop control of three elastomer beams that vary in bending stiffness. The most stiff beam is comprised of a single prismatic structure made from a single elastomer. In the next beam, increased flexibility is introduced via an indentation in the elastomer, forming a joint. The most flexible beam uses a softer elastomer in the joint section, along with an indentation. An antagonistic pair of actuators bend the joint while a pair of liquid-metal-embedded strain sensors provide angle feedback to a control loop. We were able to achieve control of the system with a proportional-integral-derivative control algorithm. The procedure we demonstrate in this work is not dependent on actuator and sensor choice and could be applied to to other hardware systems, as well as more complex multi-joint robotic structures in the future.

  7. Simulations of magnetic hysteresis loops at high temperatures

    SciTech Connect

    Plumer, M. L.; Whitehead, J. P.; Fal, T. J.; Ek, J. van; Mercer, J. I.

    2014-09-28

    The kinetic Monte-Carlo algorithm as well as standard micromagnetics are used to simulate MH loops of high anisotropy magnetic recording media at both short and long time scales over a wide range of temperatures relevant to heat-assisted magnetic recording. Microscopic parameters, common to both methods, were determined by fitting to experimental data on single-layer FePt-based media that uses the Magneto-Optic Kerr effect with a slow sweep rate of 700 Oe/s. Saturation moment, uniaxial anisotropy, and exchange constants are given an intrinsic temperature dependence based on published atomistic simulations of FePt grains with an effective Curie temperature of 680 K. Our results show good agreement between micromagnetics and kinetic Monte Carlo results over a wide range of sweep rates. Loops at the slow experimental sweep rates are found to become more square-shaped, with an increasing slope, as temperature increases from 300 K. These effects also occur at higher sweep rates, typical of recording speeds, but are much less pronounced. These results demonstrate the need for accurate determination of intrinsic thermal properties of future recording media as input to micromagnetic models as well as the sensitivity of the switching behavior of thin magnetic films to applied field sweep rates at higher temperatures.

  8. A hybrid mock circulation loop for a total artificial heart.

    PubMed

    Nestler, Frank; Bradley, Andrew P; Wilson, Stephen J; Timms, Daniel L; Frazier, O Howard; Cohn, William E

    2014-09-01

    Rotary blood pumps are emerging as a viable technology for total artificial hearts, and the development of physiological control algorithms is accelerated with new evaluation environments. In this article, we present a novel hybrid mock circulation loop (HMCL) designed specifically for evaluation of rotary total artificial hearts (rTAH). The rTAH is operated in the physical domain while all vasculature elements are embedded in the numerical domain, thus combining the strengths of both approaches: fast and easy exchange of the vasculature model together with improved controllability of the pump. Parameters, such as vascular resistance, compliance, and blood volume, can be varied dynamically in silico during operation. A hydraulic-numeric interface creates a real-time feedback loop between the physical and numerical domains. The HMCL uses computer-controlled resistance valves as actuators, thereby reducing the size and number of hydraulic elements. Experimental results demonstrate a stable interaction over a wide operational range and a high degree of flexibility. Therefore, we demonstrate that the newly created design environment can play an integral part in the hydraulic design, control development, and durability testing of rTAHs. PMID:25234760

  9. Closed-loop rehabilitation of age-related cognitive disorders.

    PubMed

    Mishra, Jyoti; Gazzaley, Adam

    2014-11-01

    Cognitive deficits are common in older adults, as a result of both the natural aging process and neurodegenerative disease. Although medical advancements have successfully prolonged the human lifespan, the challenge of remediating cognitive aging remains. The authors discuss the current state of cognitive therapeutic interventions and then present the need for development and validation of more powerful neurocognitive therapeutics. They propose that the next generation of interventions be implemented as closed-loop systems that target specific neural processing deficits, incorporate quantitative feedback to the individual and clinician, and are personalized to the individual's neurocognitive capacities using real-time performance-adaptive algorithms. This approach should be multimodal and seamlessly integrate other treatment approaches, including neurofeedback and transcranial electrical stimulation. This novel approach will involve the generation of software that engages the individual in an immersive and enjoyable game-based interface, integrated with advanced biosensing hardware, to maximally harness plasticity and assure adherence. Introducing such next-generation closed-loop neurocognitive therapeutics into the mainstream of our mental health care system will require the combined efforts of clinicians, neuroscientists, bioengineers, software game developers, and industry and policy makers working together to meet the challenges and opportunities of translational neuroscience in the 21st century. PMID:25520029

  10. Open-loop digital frequency multiplier

    NASA Technical Reports Server (NTRS)

    Moore, R. C.

    1977-01-01

    Monostable multivibrator is implemented by using digital integrated circuits where multiplier constant is too large for conventional phase-locked-loop integrated circuit. A 400 Hz clock is generated by divide-by-N counter from 1 Hz timing reference.

  11. The universal one-loop effective action

    NASA Astrophysics Data System (ADS)

    Drozd, Aleksandra; Ellis, John; Quevillon, Jérémie; You, Tevong

    2016-03-01

    We present the universal one-loop effective action for all operators of dimension up to six obtained by integrating out massive, non-degenerate multiplets. Our general expression may be applied to loops of heavy fermions or bosons, and has been checked against partial results available in the literature. The broad applicability of this approach simplifies one-loop matching from an ultraviolet model to a lower-energy effective field theory (EFT), a procedure which is now reduced to the evaluation of a combination of matrices in our universal expression, without any loop integrals to evaluate. We illustrate the relationship of our results to the Standard Model (SM) EFT, using as an example the supersymmetric stop and sbottom squark Lagrangian and extracting from our universal expression the Wilson coefficients of dimension-six operators composed of SM fields.

  12. Loop Diuretics in the Treatment of Hypertension.

    PubMed

    Malha, Line; Mann, Samuel J

    2016-04-01

    Loop diuretics are not recommended in current hypertension guidelines largely due to the lack of outcome data. Nevertheless, they have been shown to lower blood pressure and to offer potential advantages over thiazide-type diuretics. Torsemide offers advantages of longer duration of action and once daily dosing (vs. furosemide and bumetanide) and more reliable bioavailability (vs. furosemide). Studies show that the previously employed high doses of thiazide-type diuretics lower BP more than furosemide. Loop diuretics appear to have a preferable side effect profile (less hyponatremia, hypokalemia, and possibly less glucose intolerance). Studies comparing efficacy and side effect profiles of loop diuretics with the lower, currently widely prescribed, thiazide doses are needed. Research is needed to fill gaps in knowledge and common misconceptions about loop diuretic use in hypertension and to determine their rightful place in the antihypertensive arsenal. PMID:26951244

  13. Mathematical Modeling of Loop Heat Pipes

    NASA Technical Reports Server (NTRS)

    Kaya, Tarik; Ku, Jentung; Hoang, Triem T.; Cheung, Mark L.

    1998-01-01

    The primary focus of this study is to model steady-state performance of a Loop Heat Pipe (LHP). The mathematical model is based on the steady-state energy balance equations at each component of the LHP. The heat exchange between each LHP component and the surrounding is taken into account. Both convection and radiation environments are modeled. The loop operating temperature is calculated as a function of the applied power at a given loop condition. Experimental validation of the model is attempted by using two different LHP designs. The mathematical model is tested at different sink temperatures and at different elevations of the loop. Tbc comparison of the calculations and experimental results showed very good agreement (within 3%). This method proved to be a useful tool in studying steady-state LHP performance characteristics.

  14. A magnetohydrodynamic theory of coronal loop transients

    NASA Technical Reports Server (NTRS)

    Yeh, T.

    1982-01-01

    The physical and geometrical characteristics of solar coronal loop transients are described in an MHD model based on Archimedes' MHD buoyancy force. The theory was developed from interpretation of coronagraphic data, particularly from Skylab. The brightness of a loop is taken to indicate the electron density, and successive pictures reveal the electron enhancement in different columns. The forces which lift the loop off the sun surface are analyzed as an MHD buoyancy force affecting every mass element by imparting an inertial force necessary for heliocentrifugal motion. Thermal forces are responsible for transferring the ambient stress to the interior of the loop to begin the process. The kinematic and hydrostatic buoyancy overcome the gravitational force, and a flux rope can then curve upward, spiralling like a corkscrew with varying cross section around the unwinding solar magnetic field lines.

  15. Automatic Event Detection in Search for Inter-Moss Loops in IRIS Si IV Slit-Jaw Images

    NASA Technical Reports Server (NTRS)

    Fayock, Brian; Winebarger, Amy R.; De Pontieu, Bart

    2015-01-01

    The high-resolution capabilities of the Interface Region Imaging Spectrometer (IRIS) mission have allowed the exploration of the finer details of the solar magnetic structure from the chromosphere to the lower corona that have previously been unresolved. Of particular interest to us are the relatively short-lived, low-lying magnetic loops that have foot points in neighboring moss regions. These inter-moss loops have also appeared in several AIA pass bands, which are generally associated with temperatures that are at least an order of magnitude higher than that of the Si IV emission seen in the 1400 angstrom pass band of IRIS. While the emission lines seen in these pass bands can be associated with a range of temperatures, the simultaneous appearance of these loops in IRIS 1400 and AIA 171, 193, and 211 suggest that they are not in ionization equilibrium. To study these structures in detail, we have developed a series of algorithms to automatically detect signal brightening or events on a pixel-by-pixel basis and group them together as structures for each of the above data sets. These algorithms have successfully picked out all activity fitting certain adjustable criteria. The resulting groups of events are then statistically analyzed to determine which characteristics can be used to distinguish the inter-moss loops from all other structures. While a few characteristic histograms reveal that manually selected inter-moss loops lie outside the norm, a combination of several characteristics will need to be used to determine the statistical likelihood that a group of events be categorized automatically as a loop of interest. The goal of this project is to be able to automatically pick out inter-moss loops from an entire data set and calculate the characteristics that have previously been determined manually, such as length, intensity, and lifetime. We will discuss the algorithms, preliminary results, and current progress of automatic characterization.

  16. Closed loop computer control for an automatic transmission

    DOEpatents

    Patil, Prabhakar B.

    1989-01-01

    In an automotive vehicle having an automatic transmission that driveably connects a power source to the driving wheels, a method to control the application of hydraulic pressure to a clutch, whose engagement produces an upshift and whose disengagement produces a downshift, the speed of the power source, and the output torque of the transmission. The transmission output shaft torque and the power source speed are the controlled variables. The commanded power source torque and commanded hydraulic pressure supplied to the clutch are the control variables. A mathematical model is formulated that describes the kinematics and dynamics of the powertrain before, during and after a gear shift. The model represents the operating characteristics of each component and the structural arrangement of the components within the transmission being controlled. Next, a close loop feedback control is developed to determine the proper control law or compensation strategy to achieve an acceptably smooth gear ratio change, one in which the output torque disturbance is kept to a minimum and the duration of the shift is minimized. Then a computer algorithm simulating the shift dynamics employing the mathematical model is used to study the effects of changes in the values of the parameters established from a closed loop control of the clutch hydraulic and the power source torque on the shift quality. This computer simulation is used also to establish possible shift control strategies. The shift strategies determined from the prior step are reduced to an algorithm executed by a computer to control the operation of the power source and the transmission.

  17. A multiple-pass ring oscillator based dual-loop phase-locked loop

    NASA Astrophysics Data System (ADS)

    Danfeng, Chen; Junyan, Ren; Jingjing, Deng; Wei, Li; Ning, Li

    2009-10-01

    A dual-loop phase-locked loop (PLL) for wideband operation is proposed. The dual-loop architecture combines a coarse-tuning loop with a fine-tuning one, enabling a wide tuning range and low voltage-controlled oscillator (VCO) gain without poisoning phase noise and reference spur suppression performance. An analysis of the phase noise and reference spur of the dual-loop PLL is emphasized. A novel multiple-pass ring VCO is designed for the dual-loop application. It utilizes both voltage-control and current-control simultaneously in the delay cell. The PLL is fabricated in Jazz 0.18-μm RF CMOS technology. The measured tuning range is from 4.2 to 5.9 GHz. It achieves a low phase noise of -99 dBc/Hz @ 1 MHz offset from a 5.5 GHz carrier.

  18. Loop quantum cosmology in 2 +1 dimension

    NASA Astrophysics Data System (ADS)

    Zhang, Xiangdong

    2014-12-01

    As a first step to generalize the structure of loop quantum cosmology to the theories with the spacetime dimension other than four, the isotropic model of loop quantum cosmology in 2 +1 dimension is studied in this paper. We find that the classical big bang singularity is again replaced by a quantum bounce in the model. The similarities and differences between the (2 +1 )-dimensional model and the (3 +1 )-dimensional one are also discussed.

  19. Onset of inflation in loop quantum cosmology

    SciTech Connect

    Germani, Cristiano; Nelson, William; Sakellariadou, Mairi

    2007-08-15

    Using a Liouville measure, similar to the one proposed recently by Gibbons and Turok, we investigate the probability that single-field inflation with a polynomial potential can last long enough to solve the shortcomings of the standard hot big bang model, within the semiclassical regime of loop quantum cosmology. We conclude that, for such a class of inflationary models and for natural values of the loop quantum cosmology parameters, a successful inflationary scenario is highly improbable.

  20. Deployable radiator with flexible line loop

    NASA Technical Reports Server (NTRS)

    Keeler, Bryan V. (Inventor); Lehtinen, Arthur Mathias (Inventor); McGee, Billy W. (Inventor)

    2003-01-01

    Radiator assembly (10) for use on a spacecraft (12) is provided including at least one radiator panel assembly (26) repeatably movable between a panel stowed position (28) and a panel deployed position (36), at least two flexible lines (40) in fluid communication with the at least one radiator panel assembly (26) and repeatably movable between a stowage loop (42) and a flattened deployed loop (44).

  1. Bonus symmetry for super Wilson loops

    NASA Astrophysics Data System (ADS)

    Münkler, Hagen

    2016-05-01

    The Yangian level-one hypercharge generator for the super Wilson loop in { N }=4 supersymmetric Yang-Mills theory is constructed. Moreover, evidence for the presence of a corresponding symmetry generator at all higher levels is provided. The derivation is restricted to the strong-coupling description of the super Wilson loop and based on the construction of novel conserved charges for type IIB superstrings on {{AdS}}5× {{{S}}}5.

  2. Cyclic universe from Loop Quantum Gravity

    NASA Astrophysics Data System (ADS)

    Cianfrani, Francesco; Kowalski-Glikman, Jerzy; Rosati, Giacomo

    2016-02-01

    We discuss how a cyclic model for the flat universe can be constructively derived from Loop Quantum Gravity. This model has a lower bounce, at small values of the scale factor, which shares many similarities with that of Loop Quantum Cosmology. We find that Quantum Gravity corrections can be also relevant at energy densities much smaller than the Planckian one and that they can induce an upper bounce at large values of the scale factor.

  3. Tachyon matter in loop quantum cosmology

    NASA Astrophysics Data System (ADS)

    Sen, A. A.

    2006-08-01

    An analytical approach for studying the cosmological scenario with a homogeneous tachyon field within the framework of loop quantum gravity is developed. Our study is based on the semiclassical regime where space time can be approximated as a continuous manifold, but matter Hamiltonian gets nonperturbative quantum corrections. A formal correspondence between classical and loop quantum cosmology is also established. The Hamilton-Jacobi method for getting exact solutions is constructed and some exact power law as well as bouncing solutions are presented.

  4. Can Chemical Looping Combustion Use CFB Technology?

    SciTech Connect

    Gamwo, I.K.

    2006-11-01

    Circulating Fluidized Bed (CFB) technology has demonstrated an unparalleled ability to achieve low SO2 and NOx emissions for coal-fired power plants without CO2 capture. Chemical Looping combustion (CLC) is a novel fuel combustion technology which appears as a leading candidate in terms of competitiveness for CO2 removal from flue gas. This presentaion deals with the adaptation of circulating fluidized bed technology to Chemical looping combustion

  5. Gain-scheduling Control of Rotary Inverted Pendulum by Weight Optimization and H∞ Loop Shaping Procedure

    NASA Astrophysics Data System (ADS)

    Yubai, Kazuhiro; Okuhara, Kazunori; Hirai, Junji

    Gain-scheduling control is one of effective methods for plants whose dynamics changes significantly according to its operating point. A frozen parameter method is known to be a practical gain-scheduling controller synthesis, which interpolates the controllers designed at the prespecified (frozen) operating points according to the current operation point. Hyde et al. proposed a gain-scheduling control that H∞ loop shaping procedure is adopted as a controller synthesis at each operating point. H∞ loop shaping procedure is based on loop shaping of an open loop characteristic by frequency weights and is known to be effective for plants with bad condition number. However, weight selection satisfying control specifications is hard job for a designer. This paper describes the design of a suboptimal weight and a controller by means of algorithm that maximizes the robust stability margin and shapes the open loop characteristic into the desired shape at each operating point. Moreover, we formulate a weight optimization problem as a generalized eigenvalue minimization problem, which reduces the designer's burden of weight selection. Finally, we realize robust and high performance control system by scheduling both weights and controllers. The effectiveness of the proposed control system is verified in terms of the achieved robust stability margin and experimental time responses of a rotary inverted pendulum which involves strong nonlinear dynamics.

  6. Reasoning about systolic algorithms

    SciTech Connect

    Purushothaman, S.

    1986-01-01

    Systolic algorithms are a class of parallel algorithms, with small grain concurrency, well suited for implementation in VLSI. They are intended to be implemented as high-performance, computation-bound back-end processors and are characterized by a tesselating interconnection of identical processing elements. This dissertation investigates the problem of providing correctness of systolic algorithms. The following are reported in this dissertation: (1) a methodology for verifying correctness of systolic algorithms based on solving the representation of an algorithm as recurrence equations. The methodology is demonstrated by proving the correctness of a systolic architecture for optimal parenthesization. (2) The implementation of mechanical proofs of correctness of two systolic algorithms, a convolution algorithm and an optimal parenthesization algorithm, using the Boyer-Moore theorem prover. (3) An induction principle for proving correctness of systolic arrays which are modular. Two attendant inference rules, weak equivalence and shift transformation, which capture equivalent behavior of systolic arrays, are also presented.

  7. Algorithm-development activities

    NASA Technical Reports Server (NTRS)

    Carder, Kendall L.

    1994-01-01

    The task of algorithm-development activities at USF continues. The algorithm for determining chlorophyll alpha concentration, (Chl alpha) and gelbstoff absorption coefficient for SeaWiFS and MODIS-N radiance data is our current priority.

  8. Multiple Flow Loop SCADA System Implemented on the Production Prototype Loop

    SciTech Connect

    Baily, Scott A.; Dalmas, Dale Allen; Wheat, Robert Mitchell; Woloshun, Keith Albert; Dale, Gregory E.

    2015-11-16

    The following report covers FY 15 activities to develop supervisory control and data acquisition (SCADA) system for the Northstar Moly99 production prototype gas flow loop. The goal of this effort is to expand the existing system to include a second flow loop with a larger production-sized blower. Besides testing the larger blower, this system will demonstrate the scalability of our solution to multiple flow loops.

  9. Space Station evolution study oxygen loop closure

    NASA Technical Reports Server (NTRS)

    Wood, M. G.; Delong, D.

    1993-01-01

    In the current Space Station Freedom (SSF) Permanently Manned Configuration (PMC), physical scars for closing the oxygen loop by the addition of oxygen generation and carbon dioxide reduction hardware are not included. During station restructuring, the capability for oxygen loop closure was deferred to the B-modules. As such, the ability to close the oxygen loop in the U.S. Laboratory module (LAB A) and the Habitation A module (HAB A) is contingent on the presence of the B modules. To base oxygen loop closure of SSF on the funding of the B-modules may not be desirable. Therefore, this study was requested to evaluate the necessary hooks and scars in the A-modules to facilitate closure of the oxygen loop at or subsequent to PMC. The study defines the scars for oxygen loop closure with impacts to cost, weight and volume and assesses the effects of byproduct venting. In addition, the recommended scenarios for closure with regard to topology and packaging are presented.

  10. Flare Half-Loops: What Are They?

    NASA Astrophysics Data System (ADS)

    McKenzie, David Eugene; Guidoni, S. E.; Longcope, D. W.; Yoshimura, K.

    2012-05-01

    The M1.4 flare of 28 January 2011 has a remarkable resemblance to the famous "Tsuneta candle-flame" flare of 1992. It was observed with Hinode/XRT, SDO/AIA, and STEREO (A)/EUVI, resulting in higher resolution, greater temperature coverage, and stereoscopic views of this iconic structure. The high temperature images reveal a brightening that grows in size to form a tower-like structure at the top of the arcade. They also show that loops which are successively connected to this tower develop a density increase in one of their legs that can exceed twice the density of the other leg, giving the appearance of "half loops". These jumps in density last for an extended period of time. On the other hand, XRT filter ratios suggest that temperature is approximately uniform along the entire loop. XRT filter-ratio density maps corroborate that the brighter legs have higher density than the fainter halves. The tower is associated with a localized density increase, with even higher densities than either leg of the loop. This spatial variation of density may correspond to a shock at the top of the loops. We use STEREO images to show that the half loop brightening is not a line-of-sight projection effect of the type suggested by Forbes & Acton. This work is supported under contract SP02H3901R from Lockheed-Martin to MSU, and under contract NNM07AB07C with the Harvard-Smithsonian Astrophysical Observatory.

  11. Accurate Finite Difference Algorithms

    NASA Technical Reports Server (NTRS)

    Goodrich, John W.

    1996-01-01

    Two families of finite difference algorithms for computational aeroacoustics are presented and compared. All of the algorithms are single step explicit methods, they have the same order of accuracy in both space and time, with examples up to eleventh order, and they have multidimensional extensions. One of the algorithm families has spectral like high resolution. Propagation with high order and high resolution algorithms can produce accurate results after O(10(exp 6)) periods of propagation with eight grid points per wavelength.

  12. Open-loop control of liquid-crystal spatial light modulators for vertical atmospheric turbulence wavefront correction.

    PubMed

    Liu, Chao; Hu, Lifa; Mu, Quanquan; Cao, Zhaoliang; Xuan, Li

    2011-01-01

    We present an open-loop adaptive optics (AO) system based on two liquid-crystal spatial light modulators (LCSLMs) that profit from high precision wavefront generation and good repeatability. A wide optical bandwidth of 300 nm is designed for the system, and a new open-loop optical layout is invented to conveniently switch between the open and closed loop. The corresponding control algorithm is introduced with a loop frequency (the reciprocal of the total time delay of a correction loop) of 103 Hz. The system was mounted onto a 2.16 m telescope for vertical atmospheric turbulence correction. The full width at half-maximum of the image of the star α Boo reached 0.636 arc sec after the open-loop correction, while it was 2.12 arc sec before the correction. The result indicates that the open-loop AO system based on LCSLMs potentially has the ability to be used for general astronomical applications. PMID:21221164

  13. Quantitative model of R-loop forming structures reveals a novel level of RNA–DNA interactome complexity

    PubMed Central

    Wongsurawat, Thidathip; Jenjaroenpun, Piroon; Kwoh, Chee Keong; Kuznetsov, Vladimir

    2012-01-01

    R-loop is the structure co-transcriptionally formed between nascent RNA transcript and DNA template, leaving the non-transcribed DNA strand unpaired. This structure can be involved in the hyper-mutation and dsDNA breaks in mammalian immunoglobulin (Ig) genes, oncogenes and neurodegenerative disease related genes. R-loops have not been studied at the genome scale yet. To identify the R-loops, we developed a computational algorithm and mapped R-loop forming sequences (RLFS) onto 66 803 sequences defined by UCSC as ‘known’ genes. We found that ∼59% of these transcribed sequences contain at least one RLFS. We created R-loopDB (http://rloop.bii.a-star.edu.sg/), the database that collects all RLFS identified within over half of the human genes and links to the UCSC Genome Browser for information integration and visualisation across a variety of bioinformatics sources. We found that many oncogenes and tumour suppressors (e.g. Tp53, BRCA1, BRCA2, Kras and Ptprd) and neurodegenerative diseases related genes (e.g. ATM, Park2, Ptprd and GLDC) could be prone to significant R-loop formation. Our findings suggest that R-loops provide a novel level of RNA–DNA interactome complexity, playing key roles in gene expression controls, mutagenesis, recombination process, chromosomal rearrangement, alternative splicing, DNA-editing and epigenetic modifications. RLFSs could be used as a novel source of prospective therapeutic targets. PMID:22121227

  14. Rare Event Detection Algorithm Of Water Quality

    NASA Astrophysics Data System (ADS)

    Ungs, M. J.

    2011-12-01

    A novel method is presented describing the development and implementation of an on-line water quality event detection algorithm. An algorithm was developed to distinguish between normal variation in water quality parameters and changes in these parameters triggered by the presence of contaminant spikes. Emphasis is placed on simultaneously limiting the number of false alarms (which are called false positives) that occur and the number of misses (called false negatives). The problem of excessive false alarms is common to existing change detection algorithms. EPA's standard measure of evaluation for event detection algorithms is to have a false alarm rate of less than 0.5 percent and a false positive rate less than 2 percent (EPA 817-R-07-002). A detailed description of the algorithm's development is presented. The algorithm is tested using historical water quality data collected by a public water supply agency at multiple locations and using spiking contaminants developed by the USEPA, Water Security Division. The water quality parameters of specific conductivity, chlorine residual, total organic carbon, pH, and oxidation reduction potential are considered. Abnormal data sets are generated by superimposing water quality changes on the historical or baseline data. Eddies-ET has defined reaction expressions which specify how the peak or spike concentration of a particular contaminant affects each water quality parameter. Nine default contaminants (Eddies-ET) were previously derived from pipe-loop tests performed at EPA's National Homeland Security Research Center (NHSRC) Test and Evaluation (T&E) Facility. A contaminant strength value of approximately 1.5 is considered to be a significant threat. The proposed algorithm has been able to achieve a combined false alarm rate of less than 0.03 percent for both false positives and for false negatives using contaminant spikes of strength 2 or more.

  15. PREFACE: Time-resolved scanning tunnelling microscopy Time-resolved scanning tunnelling microscopy

    NASA Astrophysics Data System (ADS)

    Zandvliet, Harold J. W.; Lin, Nian

    2010-07-01

    Scanning tunnelling microscopy has revolutionized our ability to image, manipulate, and investigate solid surfaces on the length scale of individual atoms and molecules. The strength of this technique lies in its imaging capabilities, since for many scientists 'seeing is believing'. However, scanning tunnelling microscopy also suffers from a severe limitation, namely its poor time resolution. Recording a scanning tunnelling microscopy image typically requires a few tens of seconds for a conventional scanning tunnelling microscope to a fraction of a second for a specially designed fast scanning tunnelling microscope. Designing and building such a fast scanning tunnelling microscope is a formidable task in itself and therefore, only a limited number of these microscopes have been built [1]. There is, however, another alternative route to significantly enhance the time resolution of a scanning tunnelling microscope. In this alternative method, the tunnelling current is measured as a function of time with the feedback loop switched off. The time resolution is determined by the bandwidth of the IV converter rather than the cut-off frequency of the feedback electronics. Such an approach requires a stable microscope and goes, of course, at the expense of spatial information. In this issue, we have collected a set of papers that gives an impression of the current status of this rapidly emerging field [2]. One of the very first attempts to extract information from tunnel current fluctuations was reported by Tringides' group in the mid-1990s [3]. They showed that the collective diffusion coefficient can be extracted from the autocorrelation of the time-dependent tunnelling current fluctuations produced by atom motion in and out of the tunnelling junction. In general, current-time traces provide direct information on switching/conformation rates and distributions of residence times. In the case where these processes are thermally induced it is rather straightforward to map

  16. The EF loop in green proteorhodopsin affects conformation and photocycle dynamics.

    PubMed

    Mehler, Michaela; Scholz, Frank; Ullrich, Sandra J; Mao, Jiafei; Braun, Markus; Brown, Lynda J; Brown, Richard C D; Fiedler, Sarah A; Becker-Baldus, Johanna; Wachtveitl, Josef; Glaubitz, Clemens

    2013-07-16

    The proteorhodopsin family consists of retinal proteins of marine bacterial origin with optical properties adjusted to their local environments. For green proteorhodopsin, a highly specific mutation in the EF loop, A178R, has been found to cause a surprisingly large redshift of 20 nm despite its distance from the chromophore. Here, we analyze structural and functional consequences of this EF loop mutation by time-resolved optical spectroscopy and solid-state NMR. We found that the primary photoreaction and the formation of the K-like photo intermediate is almost pH-independent and slower compared to the wild-type, whereas the decay of the K-intermediate is accelerated, suggesting structural changes within the counterion complex upon mutation. The photocycle is significantly elongated mainly due to an enlarged lifetime of late photo intermediates. Multidimensional MAS-NMR reveals mutation-induced chemical shift changes propagating from the EF loop to the chromophore binding pocket, whereas dynamic nuclear polarization-enhanced (13)C-double quantum MAS-NMR has been used to probe directly the retinylidene conformation. Our data show a modified interaction network between chromophore, Schiff base, and counterion complex explaining the altered optical and kinetic properties. In particular, the mutation-induced distorted structure in the EF loop weakens interactions, which help reorienting helix F during the reprotonation step explaining the slower photocycle. These data lead to the conclusion that the EF loop plays an important role in proton uptake from the cytoplasm but our data also reveal a clear interaction pathway between the EF loop and retinal binding pocket, which might be an evolutionary conserved communication pathway in retinal proteins. PMID:23870260

  17. The EF Loop in Green Proteorhodopsin Affects Conformation and Photocycle dynamics

    PubMed Central

    Mehler, Michaela; Scholz, Frank; Ullrich, Sandra J.; Mao, Jiafei; Braun, Markus; Brown, Lynda J.; Brown, Richard C.D.; Fiedler, Sarah A.; Becker-Baldus, Johanna; Wachtveitl, Josef; Glaubitz, Clemens

    2013-01-01

    The proteorhodopsin family consists of retinal proteins of marine bacterial origin with optical properties adjusted to their local environments. For green proteorhodopsin, a highly specific mutation in the EF loop, A178R, has been found to cause a surprisingly large redshift of 20 nm despite its distance from the chromophore. Here, we analyze structural and functional consequences of this EF loop mutation by time-resolved optical spectroscopy and solid-state NMR. We found that the primary photoreaction and the formation of the K-like photo intermediate is almost pH-independent and slower compared to the wild-type, whereas the decay of the K-intermediate is accelerated, suggesting structural changes within the counterion complex upon mutation. The photocycle is significantly elongated mainly due to an enlarged lifetime of late photo intermediates. Multidimensional MAS-NMR reveals mutation-induced chemical shift changes propagating from the EF loop to the chromophore binding pocket, whereas dynamic nuclear polarization-enhanced 13C-double quantum MAS-NMR has been used to probe directly the retinylidene conformation. Our data show a modified interaction network between chromophore, Schiff base, and counterion complex explaining the altered optical and kinetic properties. In particular, the mutation-induced distorted structure in the EF loop weakens interactions, which help reorienting helix F during the reprotonation step explaining the slower photocycle. These data lead to the conclusion that the EF loop plays an important role in proton uptake from the cytoplasm but our data also reveal a clear interaction pathway between the EF loop and retinal binding pocket, which might be an evolutionary conserved communication pathway in retinal proteins. PMID:23870260

  18. Algorithmic commonalities in the parallel environment

    NASA Technical Reports Server (NTRS)

    Mcanulty, Michael A.; Wainer, Michael S.

    1987-01-01

    The ultimate aim of this project was to analyze procedures from substantially different application areas to discover what is either common or peculiar in the process of conversion to the Massively Parallel Processor (MPP). Three areas were identified: molecular dynamic simulation, production systems (rule systems), and various graphics and vision algorithms. To date, only selected graphics procedures have been investigated. They are the most readily available, and produce the most visible results. These include simple polygon patch rendering, raycasting against a constructive solid geometric model, and stochastic or fractal based textured surface algorithms. Only the simplest of conversion strategies, mapping a major loop to the array, has been investigated so far. It is not entirely satisfactory.

  19. Hybrid Combustion-Gasification Chemical Looping

    SciTech Connect

    Herbert Andrus; Gregory Burns; John Chiu; Gregory Lijedahl; Peter Stromberg; Paul Thibeault

    2009-01-07

    For the past several years Alstom Power Inc. (Alstom), a leading world-wide power system manufacturer and supplier, has been in the initial stages of developing an entirely new, ultra-clean, low cost, high efficiency power plant for the global power market. This new power plant concept is based on a hybrid combustion-gasification process utilizing high temperature chemical and thermal looping technology The process consists of the oxidation, reduction, carbonation, and calcination of calcium-based compounds, which chemically react with coal, biomass, or opportunity fuels in two chemical loops and one thermal loop. The chemical and thermal looping technology can be alternatively configured as (i) a combustion-based steam power plant with CO{sub 2} capture, (ii) a hybrid combustion-gasification process producing a syngas for gas turbines or fuel cells, or (iii) an integrated hybrid combustion-gasification process producing hydrogen for gas turbines, fuel cells or other hydrogen based applications while also producing a separate stream of CO{sub 2} for use or sequestration. In its most advanced configuration, this new concept offers the promise to become the technology link from today's Rankine cycle steam power plants to tomorrow's advanced energy plants. The objective of this work is to develop and verify the high temperature chemical and thermal looping process concept at a small-scale pilot facility in order to enable AL to design, construct and demonstrate a pre-commercial, prototype version of this advanced system. In support of this objective, Alstom and DOE started a multi-year program, under this contract. Before the contract started, in a preliminary phase (Phase 0) Alstom funded and built the required small-scale pilot facility (Process Development Unit, PDU) at its Power Plant Laboratories in Windsor, Connecticut. Construction was completed in calendar year 2003. The objective for Phase I was to develop the indirect combustion loop with CO{sub 2

  20. Consistency of loop regularization method and divergence structure of QFTs Beyond one-loop order

    NASA Astrophysics Data System (ADS)

    Huang, Da; Li, Ling-Fong; Wu, Yue-Liang

    2013-04-01

    We study the problem how to deal with tensor-type two-loop integrals in the Loop Regularization (LORE) scheme. We use the two-loop photon vacuum polarization in the massless Quantum Electrodynamics (QED) as the example to present the general procedure. In the processes, we find a new divergence structure: the regulated result for each two-loop diagram contains a gauge-violating quadratic harmful divergent term even combined with their corresponding counterterm insertion diagrams. Only when we sum up over all the relevant diagrams do these quadratic harmful divergences cancel, recovering the gauge invariance and locality.

  1. Hyperspectrally-Resolved Surface Emissivity Derived Under Optically Thin Clouds

    NASA Technical Reports Server (NTRS)

    Zhou, Daniel K.; Larar, Allen M.; Liu, Xu; Smith, William L.; Strow, L. Larrabee; Yang, Ping

    2010-01-01

    Surface spectral emissivity derived from current and future satellites can and will reveal critical information about the Earth s ecosystem and land surface type properties, which can be utilized as a means of long-term monitoring of global environment and climate change. Hyperspectrally-resolved surface emissivities are derived with an algorithm utilizes a combined fast radiative transfer model (RTM) with a molecular RTM and a cloud RTM accounting for both atmospheric absorption and cloud absorption/scattering. Clouds are automatically detected and cloud microphysical parameters are retrieved; and emissivity is retrieved under clear and optically thin cloud conditions. This technique separates surface emissivity from skin temperature by representing the emissivity spectrum with eigenvectors derived from a laboratory measured emissivity database; in other words, using the constraint as a means for the emissivity to vary smoothly across atmospheric absorption lines. Here we present the emissivity derived under optically thin clouds in comparison with that under clear conditions.

  2. Fully resolved simulation of self-propulsion of aquatic organisms

    NASA Astrophysics Data System (ADS)

    Curet, Oscar M.; Alali, Ibrahim; Patankar, Neelesh A.; Maciver, Malcolm A.

    2008-11-01

    We present a computational approach for fully resolved simulation of self-propulsion of organisms through a fluid. Our implicit algorithm solves for the translational and rotational motion of the organism for prescribed deformation kinematics. In addition, the solution for the surrounding flow field is also obtained. The approach is easy to apply to the body forms of a variety of organisms. Our final goal is to use this computational tool to help in understanding the mechanisms of movement and its control in aquatic animals. In this abstract we present validation of this method for different organisms. To validate the method with respect to analytical solutions, we consider two cases: 1) a flagellum which propagates plane waves, and 2) a flagellum that propagates helical waves. To validate the method with respect to empirical measurements we consider data from two organisms: 1) jellyfish (data from John Dabiri at Caltech), and 2) zebrafish (data from Melina Hale at The University of Chicago).

  3. Time-resolved aluminium laser-induced plasma temperature measurements

    NASA Astrophysics Data System (ADS)

    Surmick, D. M.; Parigger, C. G.

    2014-11-01

    We seek to characterize the temperature decay of laser-induced plasma near the surface of an aluminium target from laser-induced breakdown spectroscopy measurements of aluminium alloy sample. Laser-induced plasma are initiated by tightly focussing 1064 nm, nanosecond pulsed Nd:YAG laser radiation. Temperatures are inferred from aluminium monoxide spectra viewed at systematically varied time delays by comparing experimental spectra to theoretical calculations with a Nelder Mead algorithm. The temperatures are found to decay from 5173 ± 270 to 3862 ± 46 Kelvin from 10 to 100 μs time delays following optical breakdown. The temperature profile along the plasma height is also inferred from spatially resolved spectral measurements and the electron number density is inferred from Stark broadened Hβ spectra.

  4. High-resolving mass spectrographs and spectrometers

    NASA Astrophysics Data System (ADS)

    Wollnik, Hermann

    2015-11-01

    Discussed are different types of high resolving mass spectrographs and spectrometers. In detail outlined are (1) magnetic and electric sector field mass spectrographs, which are the oldest systems, (2) Penning Trap mass spectrographs and spectrometers, which have achieved very high mass-resolving powers, but are technically demanding (3) time-of-flight mass spectrographs using high energy ions passing through accelerator rings, which have also achieved very high mass-resolving powers and are equally technically demanding, (4) linear time-of-flight mass spectrographs, which have become the most versatile mass analyzers for low energy ions, while the even higher performing multi-pass systems have only started to be used, (5) orbitraps, which also have achieved remarkably high mass-resolving powers for low energy ions.

  5. Time-Resolved Photoluminescence and Photovoltaics

    SciTech Connect

    Metzger, W. K.; Ahrenkiel, R. K.; Dippo, P.; Geisz, J.; Wanlass, M. W.; Kurtz, S.

    2005-01-01

    The time-resolved photoluminescence (TRPL) technique and its ability to characterize recombination in bulk photovoltaic semiconductor materials are reviewed. Results from a variety of materials and a few recent studies are summarized and compared.

  6. Multipulse interferometric frequency-resolved optical gating

    SciTech Connect

    Siders, C.W.; Siders, J.L.W.; Omenetto, F.G.; Taylor, A.J.

    1999-04-01

    The authors review multipulse interferometric frequency-resolved optical gating (MI-FROG) as a technique, uniquely suited for pump-probe coherent spectroscopy using amplified visible and near-infrared short-pulse systems and/or emissive targets, for time-resolving ultrafast phase shifts and intensity changes. Application of polarization-gate MI-FROG to the study of ultrafast ionization in gases is presented.

  7. Nonlinear Raman Techniques in Femtosecond Time Resolved Spectroscopy for the Analysis and Control of Molecular Dynamics

    SciTech Connect

    Materny, Arnulf; Konradi, Jakow; Namboodiri, Vinu; Namboodiri, Mahesh; Scaria, Abraham

    2008-11-14

    The use of four-wave mixing techniques in femtosecond time-resolved spectroscopy has considerable advantages. Due to the many degrees of freedom offered e.g. by coherent anti-Stokes Raman scattering (CARS), the dynamics even of complex systems can be analyzed in detail. Using pulse shaping techniques in combination with a self-learning loop approach, molecular mode excitation can be controlled very efficiently in a multi-photon excitation process. Results obtained from the optimal control of CARS on {beta}-carotene are discussed.

  8. Filtering algorithm for dotted interferences

    NASA Astrophysics Data System (ADS)

    Osterloh, K.; Bücherl, T.; Lierse von Gostomski, Ch.; Zscherpel, U.; Ewert, U.; Bock, S.

    2011-09-01

    An algorithm has been developed to remove reliably dotted interferences impairing the perceptibility of objects within a radiographic image. This particularly is a major challenge encountered with neutron radiographs collected at the NECTAR facility, Forschungs-Neutronenquelle Heinz Maier-Leibnitz (FRM II): the resulting images are dominated by features resembling a snow flurry. These artefacts are caused by scattered neutrons, gamma radiation, cosmic radiation, etc. all hitting the detector CCD directly in spite of a sophisticated shielding. This makes such images rather useless for further direct evaluations. One approach to resolve this problem of these random effects would be to collect a vast number of single images, to combine them appropriately and to process them with common image filtering procedures. However, it has been shown that, e.g. median filtering, depending on the kernel size in the plane and/or the number of single shots to be combined, is either insufficient or tends to blur sharp lined structures. This inevitably makes a visually controlled processing image by image unavoidable. Particularly in tomographic studies, it would be by far too tedious to treat each single projection by this way. Alternatively, it would be not only more comfortable but also in many cases the only reasonable approach to filter a stack of images in a batch procedure to get rid of the disturbing interferences. The algorithm presented here meets all these requirements. It reliably frees the images from the snowy pattern described above without the loss of fine structures and without a general blurring of the image. It consists of an iterative, within a batch procedure parameter free filtering algorithm aiming to eliminate the often complex interfering artefacts while leaving the original information untouched as far as possible.

  9. Lucas–Kanade fluid trajectories for time-resolved PIV

    NASA Astrophysics Data System (ADS)

    Yegavian, Robin; Leclaire, Benjamin; Champagnat, Frédéric; Illoul, Cédric; Losfeld, Gilles

    2016-08-01

    We introduce a new method for estimating fluid trajectories in time-resolved PIV. It relies on a Lucas–Kanade paradigm and consists in a simple and direct extension of a two-frame estimation with FOLKI-PIV (Champagnat et al 2011 Exp. Fluids 50 1169–82). The so-called Lucas–Kanade Fluid Trajectories (LKFT) are assumed to be polynomial in time, and are found as the minimizer of a global functional, in which displacements are sought so as to match the intensities of a series of images pairs in the sequence, in the least-squares sense. All pairs involve the central image, similar to other recent time-resolved approaches (FTC (Lynch and Scarano 2013 Meas. Sci. Technol. 24 035305) and FTEE (Jeon et al 2014 Exp. Fluids 55 1–16)). As switching from a two-frame to a time-resolved objective simply amounts to adding terms in a functional, no significant additional algorithmic element is required. Similar to FOLKI-PIV the method is very well suited for GPU acceleration, which is an important feature as computational complexity increases with the image sequence size. Tests on synthetic data exhibiting peak-locking show that increasing the image sequence size strongly reduces both associated bias and random error, and that LKFT has a remaining total error comparable to that of FTEE on this case. Results on case B of the third PIV challenge (Stanislas et al 2008 Exp. Fluids 45 27–71) also show its ability to drastically reduce the error in situations with low signal-to-noise ratio. These results are finally confirmed on experimental images acquired in the near-field of a low Reynolds number jet. Strong reductions in peak-locking, spatial and temporal noise compared to two-frame estimation are also observed, on the displacement components themselves, as well as on spatial or temporal derivatives, such as vorticity and material acceleration.

  10. A causal loop analysis of the sustainability of integrated community case management in Rwanda.

    PubMed

    Sarriot, Eric; Morrow, Melanie; Langston, Anne; Weiss, Jennifer; Landegger, Justine; Tsuma, Laban

    2015-04-01

    Expansion of community health services in Rwanda has come with the national scale up of integrated Community Case Management (iCCM) of malaria, pneumonia and diarrhea. We used a sustainability assessment framework as part of a large-scale project evaluation to identify factors affecting iCCM sustainability (2011). We then (2012) used causal-loop analysis to identify systems determinants of iCCM sustainability from a national systems perspective. This allows us to develop three high-probability future scenarios putting the achievements of community health at risk, and to recommend mitigating strategies. Our causal loop diagram highlights both balancing and reinforcing loops of cause and effect in the national iCCM system. Financial, political and technical scenarios carry high probability for threatening the sustainability through: (1) reduction in performance-based financing resources, (2) political shocks and erosion of political commitment for community health, and (3) insufficient progress in resolving district health systems--"building blocks"--performance gaps. In a complex health system, the consequences of choices may be delayed and hard to predict precisely. Causal loop analysis and scenario mapping make explicit complex cause-and-effects relationships and high probability risks, which need to be anticipated and mitigated. PMID:25779620

  11. Closed-loop nominal and abort atmospheric ascent guidance for rocket-powered launch vehicles

    NASA Astrophysics Data System (ADS)

    Dukeman, Greg A.

    2005-07-01

    An advanced ascent guidance algorithm for rocket-powered launch vehicles is developed. The ascent guidance function is responsible for commanding attitude, throttle and setting during the powered ascent phase of flight so that the vehicle attains target cutoff conditions in a near optimal manner while satisfying path constraints such as maximum allowed bending moment and maximum allowed axial acceleration. This algorithm cyclically solves the calculus-of-variations two-point boundary-value problem starting at vertical rise completion through orbit insertion. This is different from traditional ascent guidance algorithms which operate in an open-loop mode until the high dynamic pressure portion of the trajectory is over, at which time there is a switch to a closed loop guidance mode that operates under the assumption of negligible aerodynamic forces. The main contribution of this research is an algorithm of the predictor-corrector type wherein the state/costate system is propagated with known (navigated) initial state and guessed initial costate to predict the state/costate at engine cutoff. The initial costate guess is corrected, using a multi-dimensional Newton's method, based on errors in the terminal state constraints and the transversality conditions. Path constraints are enforced within the propagation process. A modified multiple shooting method is shown to be a very effective numerical technique for this application. Results for a single stage to orbit launch vehicle are given. In addition, the formulation for the free final time multi-arc trajectory optimization problem is given. Results for a two-stage launch vehicle burn-coast-burn ascent to orbit in a closed-loop guidance mode are shown. An abort to landing site formulation of the algorithm and numerical results are presented. A technique for numerically treating the transversality conditions is discussed that eliminates part of the analytical and coding burden associated with optimal control theory.

  12. Diagnosis of meningioma by time-resolved fluorescence spectroscopy.

    PubMed

    Butte, Pramod V; Pikul, Brian K; Hever, Aviv; Yong, William H; Black, Keith L; Marcu, Laura

    2005-01-01

    We investigate the use of time-resolved laser-induced fluorescence spectroscopy (TR-LIFS) as an adjunctive tool for the intraoperative rapid evaluation of tumor specimens and delineation of tumor from surrounding normal tissue. Tissue autofluorescence is induced with a pulsed nitrogen laser (337 nm, 1.2 ns) and the intensity decay profiles are recorded in the 370 to 500 nm spectral range with a fast digitizer (0.2 ns resolution). Experiments are conducted on excised specimens (meningioma, dura mater, cerebral cortex) from 26 patients (97 sites). Spectral intensities and time-dependent parameters derived from the time-resolved spectra of each site are used for tissue characterization. A linear discriminant analysis algorithm is used for tissue classification. Our results reveal that meningioma is characterized by unique fluorescence characteristics that enable discrimination of tumor from normal tissue with high sensitivity (>89%) and specificity (100%). The accuracy of classification is found to increase (92.8% cases in the training set and 91.8% in the cross-validated set correctly classified) when parameters from both the spectral and the time domain are used for discrimination. Our findings establish the feasibility of using TR-LIFS as a tool for the identification of meningiomas and enables further development of real-time diagnostic tools for analyzing surgical tissue specimens of meningioma or other brain tumors. PMID:16409091

  13. Time-Resolved SQUID Sensor with a Nyquist Frequency up to 25 GHz

    NASA Astrophysics Data System (ADS)

    Cui, Z.; Wang, Y. H.; Kratz, P.; Rosenberg, A. J.; Watson, C. A.; Sochnikov, I.; Fung, Y.-K.-K.; Gibson, G.; Kirtley, J. R.; Ketchen, M. B.; Moler, K. A.

    We demonstrate a time-resolved scanning Superconducting QUantum Interference Device (SQUID) sensor with an expected maximum sampling rate of 50 GHz. The time-resolved SQUID sampler is operated by a pump-probe pulse sequence and will be particularly useful in studying high-frequency magnetic devices and the transient behavior of magnetic materials. The high sampling rate is achieved through a Josephson-interferometry technique developed at IBM. We tested our sampler with flux signals of order 10 mΦ0 (where Φ0 is the magnetic flux quantum), which corresponds to 25 million Bohr magnetons located 1 micron directly below the pickup loop. Operating in this regime, our sampler will have much higher sensitivity than bulk sensors like conventional SQUIDs and much larger spatial scanning range than single-spin sensors like NV centers. The SQUID sampler will thus be well-suited to characterize individual mesoscopic samples as well as bulk samples with mesoscopic features.

  14. Super-resolved enhancing and edge deghosting (SEED) for spatiotemporally encoded single-shot MRI.

    PubMed

    Chen, Lin; Li, Jing; Zhang, Miao; Cai, Shuhui; Zhang, Ting; Cai, Congbo; Chen, Zhong

    2015-07-01

    Spatiotemporally encoded (SPEN) single-shot MRI is an ultrafast MRI technique proposed recently, which utilizes quadratic rather than linear phase profile to extract the spatial information. Compared to the echo planar imaging (EPI), this technique has great advantages in resisting field inhomogeneity and chemical shift effects. Super-resolved (SR) reconstruction is adopted to compensate the inherent low resolution of SPEN images. Due to insufficient sampling rate, the SR image is challenged by aliasing artifacts and edge ghosts. The existing SR algorithms always compromise in spatial resolution to suppress these undesirable artifacts. In this paper, we proposed a novel SR algorithm termed super-resolved enhancing and edge deghosting (SEED). Different from artifacts suppression methods, our algorithm aims at exploiting the relationship between aliasing artifacts and real signal. Based on this relationship, the aliasing artifacts can be eliminated without spatial resolution loss. According to the trait of edge ghosts, finite differences and high-pass filter are employed to extract the prior knowledge of edge ghosts. By combining the prior knowledge with compressed sensing, our algorithm can efficiently reduce the edge ghosts. The robustness of SEED is demonstrated by experiments under various situations. The results indicate that the SEED can provide better spatial resolution compared to state-of-the-art SR reconstruction algorithms in SPEN MRI. Theoretical analysis and experimental results also show that the SR images reconstructed by SEED have better spatial resolution than the images obtained with conventional k-space encoding methods under similar experimental condition. PMID:25910683

  15. Loop quantum cosmology of Bianchi IX: Inclusion of inverse triad corrections

    NASA Astrophysics Data System (ADS)

    Corichi, Alejandro; Karami, Asieh

    2016-06-01

    We consider the loop quantization of the (diagonal) Bianchi type IX cosmological model. We explore different quantization prescriptions that extend the work of Wilson-Ewing and Singh. In particular, we study two different ways of implementing the so-called inverse triad corrections. We construct the corresponding Hamiltonian constraint operators and show that the singularity is formally resolved. We find the effective equations associated with the different quantization prescriptions, and study the relation with the isotropic k = 1 model that, classically, is contained within the Bianchi IX model. Somewhat surprisingly, we find the most natural quantization does not reduce to the k = 1 model. We use geometrically defined scalar observables to explore the physical implications of each of these theories. This is the first part in a series of papers analyzing different aspects of the Bianchi IX model, with inverse corrections, within loop quantum cosmology (LQC).

  16. Induction of the lac promoter in the absence of DNA loops and the stoichiometry of induction.

    PubMed

    Oehler, Stefan; Alberti, Siegfried; Müller-Hill, Benno

    2006-01-01

    In vivo induction of the Escherichia coli lactose operon as a function of inducer concentration generates a sigmoidal curve, indicating a non-linear response. Suggested explanations for this dependence include a 2:1 inducer-repressor stoichiometry of induction, which is the currently accepted view. It is, however, known for decades that, in vitro, operator binding as a function of inducer concentration is not sigmoidal. This discrepancy between in vivo and in vitro data has so far not been resolved. We demonstrate that the in vivo non-linearity of induction is due to cooperative repression of the wild-type lac operon through DNA loop formation. In the absence of DNA loops, in vivo induction curves are hyperbolic. In the light of this result, we re-address the question of functional molecular inducer-repressor stoichiometry in induction of the lac operon. PMID:16432263

  17. Validation of the flux loop diagnostic for the measurement of launch package motion during electromagnetic launch

    NASA Astrophysics Data System (ADS)

    Koops, M.

    1992-07-01

    The development of diagnostics for studying the behavior and performance of armatures and rail accelerators is one of the subjects covered by the section EML-research of the PML-Pulse Physics Laboratory. Within that framework the development of data analysis software is in progress. This report describes a new data reduction technique to resolve armature motion from the measurement of the voltage induced in a flux loop diagnostic and the load current through the rail-armature circuit and/or its time derivative. Velocity and position of the armature as a function of time are calculated by the computer code developed. The recent improvements in data reduction are exemplified by the results of experiments performed with a 1m, 15mm square bore dipole rail accelerator. Validation of the flux loop diagnostic, in terms of accuracy, precision, range of operation, resolution, sensitivity and prospects is carried out. Suggestions to reduce the influence of the disadvantages observed are given.

  18. LOOP CALCULUS AND BELIEF PROPAGATION FOR Q-ARY ALPHABET: LOOP TOWER

    SciTech Connect

    CHERTKOV, MICHAEL; CHERNYAK, VLADIMIR

    2007-01-10

    Loop calculus introduced in [1], [2] constitutes a new theoretical tool that explicitly expresses symbol Maximum-A-Posteriori (MAP) solution of a general statistical inference problem via a solution of the Belief Propagation (BP) equations. This finding brought a new significance to the BP concept, which in the past was thought of as just a loop-free approximation. In this paper they continue a discussion of the Loop Calculus, partitioning the results into three Sections. In Section 1 they introduce a new formulation of the Loop Calculus in terms of a set of transformations (gauges) that keeping the partition function of the problem invariant. The full expression contains two terms referred to as the 'ground state' and 'excited states' contributions. The BP equations are interpreted as a special (BP) gauge fixing condition that emerges as a special orthogonality constraint between the ground state and excited states, which also selects loop contributions as the only surviving ones among the excited states. In Section 2 they demonstrate how the invariant interpretation of the Loop Calculus, introduced in Section 1, allows a natural extension to the case of a general q-ary alphabet, this is achieved via a loop tower sequential construction. The ground level in the tower is exactly equivalent to assigning one color (out of q available) to the 'ground state' and considering all 'excited' states colored in the remaining (q-1) colors, according to the loop calculus rule. Sequentially, the second level in the tower corresponds to selecting a loop from the previous step, colored in (q-1) colors, and repeating the same ground vs excited states splitting procedure into one and (q-2) colors respectively. The construction proceeds till the full (q-1)-levels deep loop tower (and the corresponding contributions to the partition function) are established. In Section 3 they discuss an ultimate relation between the loop calculus and the Bethe-Free energy variational approach of [3].

  19. An Antibody Loop Replacement Design Feasibility Study and a Loop-Swapped Dimer Structure

    SciTech Connect

    Clark, L.; Boriack-Sjodin, P; Day, E; Eldredge, J; Fitch, C; Jarpe, M; Miller, S; Li, Y; Simon, K; van Vlijmen, H

    2009-01-01

    A design approach was taken to investigate the feasibility of replacing single complementarity determining region (CDR) antibody loops. This approach may complement simpler mutation-based strategies for rational antibody design by expanding conformation space. Enormous crystal structure diversity is available, making CDR loops logical targets for structure-based design. A detailed analysis for the L1 loop shows that each loop length takes a distinct conformation, thereby allowing control on a length scale beyond that accessible to simple mutations. The L1 loop in the anti-VLA1 antibody was replaced with the L2 loop residues longer in an attempt to add an additional hydrogen bond and fill space on the antibody-antigen interface. The designs expressed well, but failed to improve affinity. In an effort to learn more, one design was crystallized and data were collected at 1.9 {angstrom} resolution. The designed L1 loop takes the qualitatively desired conformation; confirming that loop replacement by design is feasible. The crystal structure also shows that the outermost loop (residues Leu51-Ser68) is domain swapped with another monomer. Tryptophan fluorescence measurements were used to monitor unfolding as a function of temperature and indicate that the loop involved in domain swapping does not unfold below 60C. The domain-swapping is not directly responsible for the affinity loss, but is likely a side-effect of the structural instability which may contribute to affinity loss. A second round of design was successful in eliminating the dimerization through mutation of a residue (Leu51Ser) at the joint of the domain-swapped loop.

  20. Mechanics of Protein-Mediated DNA Looping

    NASA Astrophysics Data System (ADS)

    Meiners, Jens-Christian

    2009-03-01

    The formation of looped DNA-protein complexes in which a protein or protein assembly binds to multiple distant operator sites on the DNA is a common feature for many regulatory schemes on the transcriptional level. In a living cell, a multitude of mechanical forces and constraints act on these complexes, and it is imperative to understand their effects on biological function. For this aim, we study the lactose repressor as a model system for protein-mediated DNA looping in single-molecule experiments. Using a novel axial constant-force optical trapping scheme that allows us to manipulate sub-micron DNA fragments with well-controlled forces down to the 10 fN range, we show that mechanical tension in the substrate DNA of hundred femtonewton is sufficient to disrupt the loop formation process, which suggests that such mechanical tension may provide a mechanical pathway to controlling gene expression in vivo. From the force sensitivity of the loop formation process, we can also infer the topology of the looped complex; in our case an antiparallel conformation. In addition, we will present new tethered-particle microscopy data that shows lifetimes of the looped complexes that are two to three orders of magnitude shorter than those measured in biochemical competition assays and discuss possible interpretations, including the suggestion that operator binding of the lactose repressor tetramer leads to a destabilization of the dimer-dimer interface and that thus the loop breakdown process is mostly a dissociation of the tetramer into two dimers, instead, as widely assumed, an unbinding of the tetramer from the DNA.

  1. An Improved Neutron Transport Algorithm for HZETRN

    NASA Technical Reports Server (NTRS)

    Slaba, Tony C.; Blattnig, Steve R.; Clowdsley, Martha S.; Walker, Steven A.; Badavi, Francis F.

    2010-01-01

    Long term human presence in space requires the inclusion of radiation constraints in mission planning and the design of shielding materials, structures, and vehicles. In this paper, the numerical error associated with energy discretization in HZETRN is addressed. An inadequate numerical integration scheme in the transport algorithm is shown to produce large errors in the low energy portion of the neutron and light ion fluence spectra. It is further shown that the errors result from the narrow energy domain of the neutron elastic cross section spectral distributions, and that an extremely fine energy grid is required to resolve the problem under the current formulation. Two numerical methods are developed to provide adequate resolution in the energy domain and more accurately resolve the neutron elastic interactions. Convergence testing is completed by running the code for various environments and shielding materials with various energy grids to ensure stability of the newly implemented method.

  2. A Turn-Projected State-Based Conflict Resolution Algorithm

    NASA Technical Reports Server (NTRS)

    Butler, Ricky W.; Lewis, Timothy A.

    2013-01-01

    State-based conflict detection and resolution (CD&R) algorithms detect conflicts and resolve them on the basis on current state information without the use of additional intent information from aircraft flight plans. Therefore, the prediction of the trajectory of aircraft is based solely upon the position and velocity vectors of the traffic aircraft. Most CD&R algorithms project the traffic state using only the current state vectors. However, the past state vectors can be used to make a better prediction of the future trajectory of the traffic aircraft. This paper explores the idea of using past state vectors to detect traffic turns and resolve conflicts caused by these turns using a non-linear projection of the traffic state. A new algorithm based on this idea is presented and validated using a fast-time simulator developed for this study.

  3. Time synchronization over the Internet using an adaptive frequency-locked loop.

    PubMed

    Levine, J

    1999-01-01

    This paper describes the operation of an algorithm for synchronizing the time of computers using messages transmitted over packet-switched networks such as the Internet. The algorithm configures itself to realize any specified performance level at minimum cost (measured in computer cycles or network bandwidth). If the highest possible accuracy is requested, the performance will be limited by the larger of the instability of the local clock oscillator or the noise in the measurement process between the client and the server; uncertainties of about 8 ms RMS have been obtained using standard workstations and average network connections. Lower accuracy can be realized at substantially lower cost because the cost varies approximately as the inverse of the accuracy squared over a wide range of these parameters. The algorithm makes better use of scarce network bandwidth than previous methods. This improvement is realized by using a pure frequency-locked loop (rather than mixed frequency/phase locking algorithms currently proposed for the NTP) with unequal spacing between calibration cycles. The result is a cleaner separation between network noise and clock noise, which is especially important when the highest possible accuracy is desired. In addition, the algorithm is an improvement over the pure-FLL "Interlock" algorithm described previously because it is self configuring. In addition to supporting an explicit trade-off between cost and accuracy, the algorithm provides better performance than previous methods because it is better able to adapt itself to fluctuations in the asymmetry of the network delay. PMID:18238493

  4. TRANSVERSE OSCILLATIONS OF A COOLING CORONAL LOOP

    SciTech Connect

    Morton, R. J.; Erdelyi, R. E-mail: Robertus@sheffield.ac.u

    2009-12-10

    Here we present an investigation into how cooling of the plasma influences the oscillation properties (e.g., eigenfunctions and eigenfrequencies) of transverse (i.e., kink) magnetohydrodynamic (MHD) waves in a compressible magnetic flux tube embedded in a gravitationally stratified and uniformly magnetized atmosphere. The cooling is introduced via a temperature-dependent density profile. A time-dependent governing equation is derived and an approximate zeroth-order solution is then obtained. From this the influence of cooling on the behavior of the eigenfrequencies and eigenfunctions of the transverse MHD waves is determined for representative cooling timescales. It is shown analytically, as the loop cools, how the amplitude of the perturbations is found to decrease as time increases. For cooling timescales of 900-2000 s (as observed in typical EUV loops), it is shown that the cooling has important and relevant influence on the damping times of loop oscillations. Next, the theory is put to the test. The damping due to cooling is fitted to a representative observation of standing kink oscillation of EUV loops. It is also shown with an explicit approximate analytical form, how the period of the fundamental and first harmonic of the kink mode changes with time as the loop cools. A consequence of this is that the value of the period ratio P {sub 1}/P {sub 2}, a tool that is popular in magneto-seismological studies in coronal diagnostics, decreases from the value of a uniform loop, 2, as the temperature decreases. The rate of change in P {sub 1}/P {sub 2} is dependent upon the cooling timescale and is well within the observable range for typical EUV loops. Further to this, the magnitude of the anti-node shift of the eigenfunctions of the first harmonic is shown to continually increase as the loop cools, giving additional impetus to the use of spatial magneto-seismology of the solar atmosphere. Finally, we suggest that measurements of the rate of change in the

  5. Students' Understanding of Loops and Nested Loops in Computer Programming: An APOS Theory Perspective

    ERIC Educational Resources Information Center

    Cetin, Ibrahim

    2015-01-01

    The purpose of this study is to explore students' understanding of loops and nested loops concepts. Sixty-three mechanical engineering students attending an introductory programming course participated in the study. APOS (Action, Process, Object, Schema) is a constructivist theory developed originally for mathematics education. This study is the…

  6. Teachers' Attitudes and Perceptions of Looping and the Effect of Looping on Students' Academic Achievement

    ERIC Educational Resources Information Center

    Williams-Wright, Vera

    2013-01-01

    The purpose of this research study was two-fold. The first purpose was to investigate the impact of looping on academic achievement of students in selected public schools in Mississippi. The students' results on the 2010 and 2011 Mississippi Curriculum Test, Second Edition (MCT2) were used to determine whether looping students score differently in…

  7. An enriched simulation environment for evaluation of closed-loop anesthesia.

    PubMed

    Fang, Mengqi; Tao, Yuan; Wang, Youqing

    2014-02-01

    To simulate and evaluate the administration of anesthetic agents in the clinical setting, many pharmacology models have been proposed and validated, which play important roles for in silico testing of closed-loop control methods. However, to the authors' best knowledge, there is no anesthesia simulator incorporating closed-loop feedback control of anesthetic agent administration freely available and accessible to the public. Consequently, many necessary but time consuming procedures, such as selecting models from the available literatures and establishing new simulator algorithms, will be repeated by different researchers who intend to explore a novel control algorithm for closed-loop anesthesia. To address this issue, an enriched anesthesia simulator was devised in our laboratory and made freely available to the anesthesia community. This simulator was built by using MATLAB(®) (The MathWorks, Natick, MA). The GUI technology embedded in MATLAB was chosen as the tool to develop a human-machine interface. This simulator includes four types of anesthetic models, and all have been wildly used in closed-loop anesthesia studies. For each type of model, 24 virtual patients were created with significant diversity. In addition, the platform also provides a model identification module and a control method library. For the model identification module, the least square method and particle swarm optimization were presented. In the control method library, a proportional-integral-derivative control and a model predictive control were provided. Both the model identification module and the control method library are extensive and readily accessible for users to add user-defined functions. This simulator could be a benchmark-testing platform for closed-loop control of anesthesia, which is of great value and has significant development potential. For convenience, this simulator is termed as Wang's Simulator, which can be downloaded from http://www.AutomMed.org . PMID:23748601

  8. Multithermal Analysis of EIS Coronal Loops

    NASA Astrophysics Data System (ADS)

    Worley, Brian T.; Schmelz, J. T.; Pathak, S.

    2012-05-01

    Four separate active regions containing multiple coronal loops were selected for Differential Emission Measure (DEM) analysis from Hinode Extreme ultraviolet Imaging Spectrometer (EIS) data. Each loop was chosen based on its location and our ability to find a clean nearby area for background subtraction. Our analysis uses iron lines with ionization stages from Fe VIII to Fe XVI in the wavelength ranges 170 - 210 and 250 - 290 A. The twelve selected loops were then analyzed to determine if their cross-field temperature was isothermal or multithermal. This was accomplished by averaging the intensities of ten individual pixels along the length of each loop and subtracting the average intensity of ten nearby background pixels. We then used these background-subtracted values, the density from a density-sensitive line ratio, and the atomic data from the CHIANTI database to create a DEM curve for each loop. Solar physics research at the University of Memphis is supported by NSF ATM-0402729 as well as a Hinode subcontract from NASA/SAO.

  9. Coronal loops - Current-based heating processes

    NASA Technical Reports Server (NTRS)

    Beaufume, P.; Coppi, B.; Golub, L.

    1992-01-01

    Based on new observations, a theoretical model of magnetic-field related heating processes in the solar corona is given. In this model, field-aligned currents are induced along coronal loops in thin current sheaths. Excitation of instabilities involving magnetic reconnection converts the energy associated with the current-related magnetic field directly into particle energy, where the heating process proceeds via short bursts corresponding to an intermittent disruption of the current sheath configuration. Because of the relatively low transverse thermal conduction, only a small fraction of the loop volume is heated to a much higher temperature than the average value. This is consistent with experimental observations of low filling factors of hot plasmas in coronal loops. Thus the model involves a repeated sequence of dynamic events taking into account the observed loop topology, the differential emission measure distribution in the 10 exp 6 - 10 exp 7 K range, the energy balance requirements in the loop, and the probable duty cycles involved in the heating processes.

  10. Crack interaction with 3-D dislocation loops

    NASA Astrophysics Data System (ADS)

    Gao, Huajian

    CRACKS in a solid often interact with other crystal defects such as dislocation loops. The interaction effects are of 3-D character yet their analytical treatment has been mostly limited to the 2-D regime due to mathematical complications. This paper shows that distribution of the stress intensity factors along a crack front due to arbitrary dislocation loops may be expressed as simple line integrals along the loop contours. The method of analysis is based on the 3-D Bueckner-Rice weight function theory for elastic crack analysis. Our results have significantly simplified the calculations for 3-D dislocation loops produced in the plastic processes at the crack front due to highly concentrated crack tip stress fields. Examples for crack-tip 3-D loops and 2-D straight dislocations emerging from the crack tip are given to demonstrate applications of the derived formulae. The results are consistent with some previous analytical solutions existing in the literature. As further applications we also analyse straight dislocations that are parallel or perpendicular to the crack plane but are not parallel to the crack front.

  11. Bootstrapping the Three-Loop Hexagon

    SciTech Connect

    Dixon, Lance J.; Drummond, James M.; Henn, Johannes M.; /Humboldt U., Berlin /Santa Barbara, KITP

    2011-11-08

    We consider the hexagonal Wilson loop dual to the six-point MHV amplitude in planar N = 4 super Yang-Mills theory. We apply constraints from the operator product expansion in the near-collinear limit to the symbol of the remainder function at three loops. Using these constraints, and assuming a natural ansatz for the symbol's entries, we determine the symbol up to just two undetermined constants. In the multi-Regge limit, both constants drop out from the symbol, enabling us to make a non-trivial confirmation of the BFKL prediction for the leading-log approximation. This result provides a strong consistency check of both our ansatz for the symbol and the duality between Wilson loops and MHV amplitudes. Furthermore, we predict the form of the full three-loop remainder function in the multi-Regge limit, beyond the leading-log approximation, up to a few constants representing terms not detected by the symbol. Our results confirm an all-loop prediction for the real part of the remainder function in multi-Regge 3 {yields} 3 scattering. In the multi-Regge limit, our result for the remainder function can be expressed entirely in terms of classical polylogarithms. For generic six-point kinematics other functions are required.

  12. Wilson loops in supersymmetric gauge theories

    NASA Astrophysics Data System (ADS)

    Pestun, Vasily

    This thesis is devoted to several exact computations in four-dimensional supersymmetric gauge field theories. In the first part of the thesis we prove conjecture due to Erickson-Semenoff-Zarembo and Drukker-Gross which relates supersymmetric circular Wilson loop operators in the N = 4 supersymmetric Yang-Mills theory with a Gaussian matrix model. We also compute the partition function and give a new matrix model formula for the expectation value of a supersymmetric circular Wilson loop operator for the pure N = 2 and the N* = 2 supersymmetric Yang-Mills theory on a four-sphere. Circular supersymmetric Wilson loops in four-dimensional N = 2 superconformal gauge theory are treated similarly. In the second part we consider supersymmetric Wilson loops of arbitrary shape restricted to a two-dimensional sphere in the four-dimensional N = 4 supersymmetric Yang-Mills theory. We show that expectation value for these Wilson loops can be exactly computed using a two-dimensional theory closely related to the topological two-dimensional Higgs-Yang-Mills theory, or two-dimensional Yang-Mills theory for the complexified gauge group.

  13. Five-Loop Four-Point Amplitude of N=4 Super-Yang-Mills Theory

    NASA Astrophysics Data System (ADS)

    Bern, Z.; Carrasco, J. J. M.; Johansson, H.; Roiban, R.

    2012-12-01

    Using the method of maximal cuts, we construct the complete D-dimensional integrand of the five-loop four-point amplitude of N=4 super-Yang-Mills theory, including nonplanar contributions. In the critical dimension where this amplitude becomes ultraviolet divergent, we present a compact explicit expression for the nonvanishing ultraviolet divergence in terms of three vacuum integrals. This construction provides a crucial step towards obtaining the corresponding amplitude of N=8 supergravity required to resolve the general ultraviolet behavior of supergravity theories.

  14. Fatigue-Resistant Metal Hook-And-Loop Fastener

    NASA Technical Reports Server (NTRS)

    Sawaf, Bernard

    1994-01-01

    Proposed metal hook-and-loop fastener engaged and disengaged many hundreds of times without breaking. Fastener opens by mechanical action. Translation moves hooks out of loops or pushes loops away from hooks. Hooks not required to flex and, therefore, do not fail by fatigue. Lifetime much greater than that of other metal hook-and-loop fasteners, depending on flexure for disengagement such as article, "Hook-and-Loop Metal Fastener" (MSC-21586).

  15. A numerical study of the thermal stability of solar loops

    NASA Technical Reports Server (NTRS)

    Klimchuk, J. A.; Antiochos, S. K.; Mariska, J. T.

    1987-01-01

    An important property of all loops is their thermal stability. If low lying hot loops were thermally unstable, for example, a great majority of the low loops on the Sun might be expected to be cool. How small perturbations evolve in low lying, linearly unstable hot loops was determined and how high lying, linearly stable hot loops respond to large amplitude disturbances such as might be expected on the Sun were examined. Only general descriptions and results are given.

  16. A tree-loop duality relation at two loops and beyond

    NASA Astrophysics Data System (ADS)

    Bierenbaum, Isabella; Catani, Stefano; Draggiotis, Petros; Rodrigo, Germán

    2010-10-01

    The duality relation between one-loop integrals and phase-space integrals, developed in a previous work, is extended to higher-order loops. The duality relation is realized by a modification of the customary + i0 prescription of the Feynman propagators, which compensates for the absence of the multiple-cut contributions that appear in the Feynman tree theorem. We rederive the duality theorem at one-loop order in a form that is more suitable for its iterative extension to higher-loop orders. We explicitly show its application to two-and three-loop scalar master integrals, and we discuss the structure of the occurring cuts and the ensuing results in detail.

  17. Linear phase demodulator including a phase locked loop with auxiliary feedback loop

    NASA Technical Reports Server (NTRS)

    Rippy, R. R. (Inventor)

    1976-01-01

    A phase modulated wave that may have no carrier power is demodulated by a phase locked loop including a phase detector for deriving an A.C. data output signal having a magnitude and a phase indicative of the phase of the modulated wave. A feedback loop responsive to the data output signal restores power to the carrier frequency component to the loop. In one embodiment, the feedback loop includes a phase modulator responsive to the phase modulated wave and the data output signal. In a second embodiment, carrier frequency power is restored by differentiating the data output signal and supplying the differentiated signal to an input of a voltage controlled oscillator included in the phase locked loop.

  18. Three-loop hard-thermal-loop free energy for QED

    SciTech Connect

    Andersen, Jens O.; Strickland, Michael; Su, Nan

    2009-10-15

    We calculate the free energy of a hot gas of electrons and photons to three loops using the hard-thermal-loop perturbation theory reorganization of finite-temperature perturbation theory. We calculate the free energy through three loops by expanding in a power series in m{sub D}/T, m{sub f}/T, and e{sup 2}, where m{sub D} and m{sub f} are thermal masses and e is the coupling constant. We demonstrate that the hard-thermal-loop perturbation reorganization improves the convergence of the successive approximations to the QED free energy at large coupling, e{approx}2. The reorganization is gauge invariant by construction, and due to cancellation among various contributions, we obtain a completely analytic result for the resummed thermodynamic potential at three loops. Finally, we compare our result with similar calculations that use the {phi}-derivable approach.

  19. Semioptimal practicable algorithmic cooling

    SciTech Connect

    Elias, Yuval; Mor, Tal; Weinstein, Yossi

    2011-04-15

    Algorithmic cooling (AC) of spins applies entropy manipulation algorithms in open spin systems in order to cool spins far beyond Shannon's entropy bound. Algorithmic cooling of nuclear spins was demonstrated experimentally and may contribute to nuclear magnetic resonance spectroscopy. Several cooling algorithms were suggested in recent years, including practicable algorithmic cooling (PAC) and exhaustive AC. Practicable algorithms have simple implementations, yet their level of cooling is far from optimal; exhaustive algorithms, on the other hand, cool much better, and some even reach (asymptotically) an optimal level of cooling, but they are not practicable. We introduce here semioptimal practicable AC (SOPAC), wherein a few cycles (typically two to six) are performed at each recursive level. Two classes of SOPAC algorithms are proposed and analyzed. Both attain cooling levels significantly better than PAC and are much more efficient than the exhaustive algorithms. These algorithms are shown to bridge the gap between PAC and exhaustive AC. In addition, we calculated the number of spins required by SOPAC in order to purify qubits for quantum computation. As few as 12 and 7 spins are required (in an ideal scenario) to yield a mildly pure spin (60% polarized) from initial polarizations of 1% and 10%, respectively. In the latter case, about five more spins are sufficient to produce a highly pure spin (99.99% polarized), which could be relevant for fault-tolerant quantum computing.

  20. Toward GEOS-6, A Global Cloud System Resolving Atmospheric Model

    NASA Technical Reports Server (NTRS)

    Putman, William M.

    2010-01-01

    NASA is committed to observing and understanding the weather and climate of our home planet through the use of multi-scale modeling systems and space-based observations. Global climate models have evolved to take advantage of the influx of multi- and many-core computing technologies and the availability of large clusters of multi-core microprocessors. GEOS-6 is a next-generation cloud system resolving atmospheric model that will place NASA at the forefront of scientific exploration of our atmosphere and climate. Model simulations with GEOS-6 will produce a realistic representation of our atmosphere on the scale of typical satellite observations, bringing a visual comprehension of model results to a new level among the climate enthusiasts. In preparation for GEOS-6, the agency's flagship Earth System Modeling Framework [JDl] has been enhanced to support cutting-edge high-resolution global climate and weather simulations. Improvements include a cubed-sphere grid that exposes parallelism; a non-hydrostatic finite volume dynamical core, and algorithm designed for co-processor technologies, among others. GEOS-6 represents a fundamental advancement in the capability of global Earth system models. The ability to directly compare global simulations at the resolution of spaceborne satellite images will lead to algorithm improvements and better utilization of space-based observations within the GOES data assimilation system