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Sample records for algorithm substantial flexibility

  1. Flexible Phrase Based Query Handling Algorithms.

    ERIC Educational Resources Information Center

    Wilbur, W. John; Kim, Won

    2001-01-01

    Flexibility in query handling can be important if one types a search engine query that is misspelled, contains terms not in the database, or requires knowledge of a controlled vocabulary. Presents results of experiments that suggest the optimal form of similarity functions that are applicable to the task of phrase based retrieval to find either…

  2. OSPREY: Protein Design with Ensembles, Flexibility, and Provable Algorithms

    PubMed Central

    Gainza, Pablo; Roberts, Kyle E.; Georgiev, Ivelin; Lilien, Ryan H.; Keedy, Daniel A.; Chen, Cheng-Yu; Reza, Faisal; Anderson, Amy C.; Richardson, David C.; Richardson, Jane S.; Donald, Bruce R.

    2013-01-01

    Summary We have developed a suite of protein redesign algorithms that improves realistic in silico modeling of proteins. These algorithms are based on three characteristics that make them unique: (1) improved flexibility of the protein backbone, protein side chains, and ligand to accurately capture the conformational changes that are induced by mutations to the protein sequence; (2) modeling of proteins and ligands as ensembles of low-energy structures to better approximate binding affinity; and (3) a globally-optimal protein design search, guaranteeing that the computational predictions are optimal with respect to the input model. Here, we illustrate the importance of these three characteristics. We then describe OSPREY, a protein redesign suite that implements our protein design algorithms. OSPREY has been used prospectively, with experimental validation, in several biomedically-relevant settings. We show in detail how OSPREY has been used to predict resistance mutations and explain why improved flexibility, ensembles, and provability are essential for this application. PMID:23422427

  3. A flexible unstructured mesh generation algorithm suitable for block partitioning

    SciTech Connect

    Karamete, B.K.

    1996-12-31

    This paper describes the logic of a dynamic algorithm for an arbitrarily prescribed geometry. The generated meshes show Delaunay property both in 2D and 3D. The algorithm requires minimal surface information in 3D. The surface triangles appear as the direct consequence of interior tetrahedration. The adopted successive refinement scheme results in such a node distribution that it is not needed to check boundary conformity. Further computational saving is provided by using a special binary tree (ADT). The generating front can not be determined a-priori as opposed to the moving front techniques. This feature can effectively be used to partition the geometry into equal element sized blocks while generating the mesh for parallel computing purposes. The algorithm shows flexibility to split the geometry into blocks at mesh generation time.

  4. A combined algorithm for minimum time slewing of flexible spacecraft

    NASA Technical Reports Server (NTRS)

    Bainum, P. M.; Li, F.; Xu, J.

    1994-01-01

    The use of Pontryagin's Maximum Principle for the large-angle slewing of large flexible structures usually results in the so-called two-point boundary-value problem (TPBVP), in which many requirements (e.g., minimum time, small flexible amplitude, and limited control powers, etc.) must be satisfied simultaneously. The successful solution of this problem depends largely on the use of an efficient numerical computational algorithm. There are many candidate algorithms available for his problem (e.g., quasilinearization, gradient, and shooting, etc.). In this paper, a proposed algorithm, which combines the quasilinearization method with a time shortening technique and a shooting method, is applied to the minimum-time, three-dimensional, and large-angle maneuver of flexible spacecraft, particularly the orbiting Spacecraft Control Laboratory Experiment (SCOLE) configuration. Theoretically, the nonlinear TPBVP can be solved only through the shooting method to find the 'exact' switching times for the bang-bang controls. However, computationally, a suitable guess for the missing initial costates is crucial because the convergence range of the unknown initial costates is usually narrow, especially for systems with high dimensions and when a multi-bang-bang control strategy is needed. On the other hand, the problems of near minimum time attitude maneuver of general rigid spacecraft and fast slewing of flexible spacecraft have been examined by the authors through a numerical approach based on the quasilinearization algorithm with a time shortening technique. Computational results have demonstrated its broad convergence range and insensitivity to initial costate choices. Consequently, a combined approach is naturally suggested here to solve the minimum time slewing problem. That is, in the computational process, the quasilinearization method is used first to obtain a near minimum time solution. Then, the acquired converged initial costates from the quasilinearization approach

  5. A genetic algorithm based method for docking flexible molecules

    SciTech Connect

    Judson, R.S.; Jaeger, E.P.; Treasurywala, A.M.

    1993-11-01

    The authors describe a computational method for docking flexible molecules into protein binding sites. The method uses a genetic algorithm (GA) to search the combined conformation/orientation space of the molecule to find low energy conformation. Several techniques are described that increase the efficiency of the basic search method. These include the use of several interacting GA subpopulations or niches; the use of a growing algorithm that initially docks only a small part of the molecule; and the use of gradient minimization during the search. To illustrate the method, they dock Cbz-GlyP-Leu-Leu (ZGLL) into thermolysin. This system was chosen because a well refined crystal structure is available and because another docking method had previously been tested on this system. Their method is able to find conformations that lie physically close to and in some cases lower in energy than the crystal conformation in reasonable periods of time on readily available hardware.

  6. A flexible algorithm for calculating pair interactions on SIMD architectures

    NASA Astrophysics Data System (ADS)

    Páll, Szilárd; Hess, Berk

    2013-12-01

    Calculating interactions or correlations between pairs of particles is typically the most time-consuming task in particle simulation or correlation analysis. Straightforward implementations using a double loop over particle pairs have traditionally worked well, especially since compilers usually do a good job of unrolling the inner loop. In order to reach high performance on modern CPU and accelerator architectures, single-instruction multiple-data (SIMD) parallelization has become essential. Avoiding memory bottlenecks is also increasingly important and requires reducing the ratio of memory to arithmetic operations. Moreover, when pairs only interact within a certain cut-off distance, good SIMD utilization can only be achieved by reordering input and output data, which quickly becomes a limiting factor. Here we present an algorithm for SIMD parallelization based on grouping a fixed number of particles, e.g. 2, 4, or 8, into spatial clusters. Calculating all interactions between particles in a pair of such clusters improves data reuse compared to the traditional scheme and results in a more efficient SIMD parallelization. Adjusting the cluster size allows the algorithm to map to SIMD units of various widths. This flexibility not only enables fast and efficient implementation on current CPUs and accelerator architectures like GPUs or Intel MIC, but it also makes the algorithm future-proof. We present the algorithm with an application to molecular dynamics simulations, where we can also make use of the effective buffering the method introduces.

  7. Algorithm development for the control design of flexible structures

    NASA Technical Reports Server (NTRS)

    Skelton, R. E.

    1983-01-01

    The critical problems associated with the control of highly damped flexible structures are outlined. The practical problems include: high performance; assembly in space, configuration changes; on-line controller software design; and lack of test data. Underlying all of these problems is the central problem of modeling errors. To justify the expense of a space structure, the performance requirements will necessarily be very severe. On the other hand, the absence of economical tests precludes the availability of reliable data before flight. A design algorithm is offered which: (1) provides damping for a larger number of modes than the optimal attitude controller controls; (2) coordinates the rate of feedback design with the attitude control design by use of a similar cost function; and (3) provides model reduction and controller reduction decisions which are systematically connected to the mathematical statement of the control objectives and the disturbance models.

  8. A Novel Flexible Inertia Weight Particle Swarm Optimization Algorithm.

    PubMed

    Amoshahy, Mohammad Javad; Shamsi, Mousa; Sedaaghi, Mohammad Hossein

    2016-01-01

    Particle swarm optimization (PSO) is an evolutionary computing method based on intelligent collective behavior of some animals. It is easy to implement and there are few parameters to adjust. The performance of PSO algorithm depends greatly on the appropriate parameter selection strategies for fine tuning its parameters. Inertia weight (IW) is one of PSO's parameters used to bring about a balance between the exploration and exploitation characteristics of PSO. This paper proposes a new nonlinear strategy for selecting inertia weight which is named Flexible Exponential Inertia Weight (FEIW) strategy because according to each problem we can construct an increasing or decreasing inertia weight strategy with suitable parameters selection. The efficacy and efficiency of PSO algorithm with FEIW strategy (FEPSO) is validated on a suite of benchmark problems with different dimensions. Also FEIW is compared with best time-varying, adaptive, constant and random inertia weights. Experimental results and statistical analysis prove that FEIW improves the search performance in terms of solution quality as well as convergence rate. PMID:27560945

  9. A Novel Flexible Inertia Weight Particle Swarm Optimization Algorithm

    PubMed Central

    Shamsi, Mousa; Sedaaghi, Mohammad Hossein

    2016-01-01

    Particle swarm optimization (PSO) is an evolutionary computing method based on intelligent collective behavior of some animals. It is easy to implement and there are few parameters to adjust. The performance of PSO algorithm depends greatly on the appropriate parameter selection strategies for fine tuning its parameters. Inertia weight (IW) is one of PSO’s parameters used to bring about a balance between the exploration and exploitation characteristics of PSO. This paper proposes a new nonlinear strategy for selecting inertia weight which is named Flexible Exponential Inertia Weight (FEIW) strategy because according to each problem we can construct an increasing or decreasing inertia weight strategy with suitable parameters selection. The efficacy and efficiency of PSO algorithm with FEIW strategy (FEPSO) is validated on a suite of benchmark problems with different dimensions. Also FEIW is compared with best time-varying, adaptive, constant and random inertia weights. Experimental results and statistical analysis prove that FEIW improves the search performance in terms of solution quality as well as convergence rate. PMID:27560945

  10. The Path-of-Probability Algorithm for Steering and Feedback Control of Flexible Needles

    PubMed Central

    Park, Wooram; Wang, Yunfeng; Chirikjian, Gregory S.

    2010-01-01

    In this paper we develop a new framework for path planning of flexible needles with bevel tips. Based on a stochastic model of needle steering, the probability density function for the needle tip pose is approximated as a Gaussian. The means and covariances are estimated using an error propagation algorithm which has second order accuracy. Then we adapt the path-of-probability (POP) algorithm to path planning of flexible needles with bevel tips. We demonstrate how our planning algorithm can be used for feedback control of flexible needles. We also derive a closed-form solution for the port placement problem for finding good insertion locations for flexible needles in the case when there are no obstacles. Furthermore, we propose a new method using reference splines with the POP algorithm to solve the path planning problem for flexible needles in more general cases that include obstacles. PMID:21151708

  11. A flexible Mth power carrier phase estimation algorithm for coherent optical receiver

    NASA Astrophysics Data System (ADS)

    Zhang, Yong; Wang, Yulong

    2016-05-01

    Although Mth power carrier phase estimation (PE) algorithm has been investigated intensively in coherent optical phase-shift-keying (PSK) system, block length effect impacts system performance and increases hardware complexity. In this paper, a flexible Mth power carrier PE algorithm is proposed to remove the effect of block length on system performance. We take into account the time-varying phase noise, instead of the assumption of constant phase noise over the entire observation interval. The weighted factors obtained from maximum likelihood method are introduced to eliminate the block length effect. Furthermore, we derive the analytical expression of phase error variance for the performance prediction of coherent receiver with the flexible Mth power. Bit error ratio (BER) performance of coherent receiver is evaluated and compared through both theoretical derivation and Monte Carlo simulation. The results show that by using the flexible Mth power algorithm, signal noise ratio (SNR) improvement over conventional Mth power algorithm with fixed block length of 20 and 40 at BER of 10-5 is 0.47 dB and 2.18 dB, when the linewidth per laser is 2 MHz. By employing our flexible Mth power algorithm, SNR improvement over conventional Mth power algorithm with optimum block length will be larger as increasing laser linewidth . It means our flexible Mth algorithm is more effective for mitigating phase noise than the conventional Mth power algorithm.

  12. Flexible, efficient and robust algorithm for parallel execution and coupling of components in a framework

    NASA Astrophysics Data System (ADS)

    Tóth, Gábor

    2006-05-01

    We describe a general algorithm suitable for executing and coupling components of a software framework on a parallel computer. The requirements of a flexible, efficient and robust algorithm are defined precisely, and the motivation for the requirements is demonstrated on several examples. In short, the requirements are the following: (i) the algorithm should allow arbitrary distribution of processors among the components, (ii) it should allow arbitrary coupling schedule between the components, (iii) it should not use any inter-processor communication other than already required by the components and their couplings, and (iv) it should never get into a dead-lock. We show that the proposed algorithm based on the Temporal and Predefined Ordering of Tasks (TPOT) satisfies all these requirements. The TPOT algorithm has been implemented in the Space Weather Modeling Framework. The flexibility and efficiency of the algorithm is demonstrated with several examples.

  13. ULTRASONIC IMAGING USING A FLEXIBLE ARRAY: IMPROVEMENTS TO THE MAXIMUM CONTRAST AUTOFOCUS ALGORITHM

    SciTech Connect

    Hunter, A. J.; Drinkwater, B. W.; Wilcox, P. D.

    2009-03-03

    In previous work, we have presented the maximum contrast autofocus algorithm for estimating unknown imaging parameters, e.g., for imaging through complicated surfaces using a flexible ultrasonic array. This paper details recent improvements to the algorithm. The algorithm operates by maximizing the image contrast metric with respect to the imaging parameters. For a flexible array, the relative positions of the array elements are parameterized using a cubic spline function and the spline control points are estimated by iterative maximisation of the image contrast via simulated annealing. The resultant spline gives an estimate of the array geometry and the profile of the surface that it has conformed to, allowing the generation of a well-focused image. A pre-processing step is introduced to obtain an initial estimate of the array geometry, reducing the time taken for the algorithm to convergence. Experimental results are demonstrated using a flexible array prototype.

  14. A Parallel Ghosting Algorithm for The Flexible Distributed Mesh Database

    DOE PAGESBeta

    Mubarak, Misbah; Seol, Seegyoung; Lu, Qiukai; Shephard, Mark S.

    2013-01-01

    Critical to the scalability of parallel adaptive simulations are parallel control functions including load balancing, reduced inter-process communication and optimal data decomposition. In distributed meshes, many mesh-based applications frequently access neighborhood information for computational purposes which must be transmitted efficiently to avoid parallel performance degradation when the neighbors are on different processors. This article presents a parallel algorithm of creating and deleting data copies, referred to as ghost copies, which localize neighborhood data for computation purposes while minimizing inter-process communication. The key characteristics of the algorithm are: (1) It can create ghost copies of any permissible topological order inmore » a 1D, 2D or 3D mesh based on selected adjacencies. (2) It exploits neighborhood communication patterns during the ghost creation process thus eliminating all-to-all communication. (3) For applications that need neighbors of neighbors, the algorithm can create n number of ghost layers up to a point where the whole partitioned mesh can be ghosted. Strong and weak scaling results are presented for the IBM BG/P and Cray XE6 architectures up to a core count of 32,768 processors. The algorithm also leads to scalable results when used in a parallel super-convergent patch recovery error estimator, an application that frequently accesses neighborhood data to carry out computation.« less

  15. An Improved Artificial Bee Colony Algorithm for Solving Hybrid Flexible Flowshop With Dynamic Operation Skipping.

    PubMed

    Li, Jun-Qing; Pan, Quan-Ke; Duan, Pei-Yong

    2016-06-01

    In this paper, we propose an improved discrete artificial bee colony (DABC) algorithm to solve the hybrid flexible flowshop scheduling problem with dynamic operation skipping features in molten iron systems. First, each solution is represented by a two-vector-based solution representation, and a dynamic encoding mechanism is developed. Second, a flexible decoding strategy is designed. Next, a right-shift strategy considering the problem characteristics is developed, which can clearly improve the solution quality. In addition, several skipping and scheduling neighborhood structures are presented to balance the exploration and exploitation ability. Finally, an enhanced local search is embedded in the proposed algorithm to further improve the exploitation ability. The proposed algorithm is tested on sets of the instances that are generated based on the realistic production. Through comprehensive computational comparisons and statistical analysis, the highly effective performance of the proposed DABC algorithm is favorably compared against several presented algorithms, both in solution quality and efficiency. PMID:26126292

  16. A Flexible Reservation Algorithm for Advance Network Provisioning

    SciTech Connect

    Balman, Mehmet; Chaniotakis, Evangelos; Shoshani, Arie; Sim, Alex

    2010-04-12

    Many scientific applications need support from a communication infrastructure that provides predictable performance, which requires effective algorithms for bandwidth reservations. Network reservation systems such as ESnet's OSCARS, establish guaranteed bandwidth of secure virtual circuits for a certain bandwidth and length of time. However, users currently cannot inquire about bandwidth availability, nor have alternative suggestions when reservation requests fail. In general, the number of reservation options is exponential with the number of nodes n, and current reservation commitments. We present a novel approach for path finding in time-dependent networks taking advantage of user-provided parameters of total volume and time constraints, which produces options for earliest completion and shortest duration. The theoretical complexity is only O(n2r2) in the worst-case, where r is the number of reservations in the desired time interval. We have implemented our algorithm and developed efficient methodologies for incorporation into network reservation frameworks. Performance measurements confirm the theoretical predictions.

  17. Sensor failure detection and isolation in flexible structures using the eigensystem realization algorithm

    NASA Astrophysics Data System (ADS)

    Zimmerman, David C.; Lyde, Terri L.

    Sensor failure detection and isolation (FDI) for flexible structures is approached from a system realization perspective. Instead of using hardware or analytical model redundancy, system realization is utilized to provide an experimental model based redundancy. The FDI algorithm utilizes the eigensystem realization algorithm to determine a minimum-order state space realization of the structure in the presence of noisy measurements. The FDI algorithm utilizes statistical comparisons of successive realizations to detect and isolate the failed sensor component. Due to the nature in which the FDI algorithm is formulated, it is also possible to classify the failure mode of the sensor. Results are presented using both numerically simulated and actual experimental data.

  18. A comparison of force control algorithms for robots in contact with flexible environments

    NASA Technical Reports Server (NTRS)

    Wilfinger, Lee S.

    1992-01-01

    In order to perform useful tasks, the robot end-effector must come into contact with its environment. For such tasks, force feedback is frequently used to control the interaction forces. Control of these forces is complicated by the fact that the flexibility of the environment affects the stability of the force control algorithm. Because of the wide variety of different materials present in everyday environments, it is necessary to gain an understanding of how environmental flexibility affects the stability of force control algorithms. This report presents the theory and experimental results of two force control algorithms: Position Accommodation Control and Direct Force Servoing. The implementation of each of these algorithms on a two-arm robotic test bed located in the Center for Intelligent Robotic Systems for Space Exploration (CIRSSE) is discussed in detail. The behavior of each algorithm when contacting materials of different flexibility is experimentally determined. In addition, several robustness improvements to the Direct Force Servoing algorithm are suggested and experimentally verified. Finally, a qualitative comparison of the force control algorithms is provided, along with a description of a general tuning process for each control method.

  19. Flexibility.

    ERIC Educational Resources Information Center

    Humphrey, L. Dennis

    1981-01-01

    Flexibility is an important aspect of all sports and recreational activities. Flexibility can be developed and maintained by stretching exercises. Exercises designed to develop flexibility in ankle joints, knees, hips, and the lower back are presented. (JN)

  20. MEPSA: A flexible peak search algorithm designed for uniformly spaced time series

    NASA Astrophysics Data System (ADS)

    Guidorzi, C.

    2015-04-01

    We present a novel algorithm aimed at identifying peaks within a uniformly sampled time series affected by uncorrelated Gaussian noise. The algorithm, called "MEPSA" (multiple excess peak search algorithm), essentially scans the time series at different timescales by comparing a given peak candidate with a variable number of adjacent bins. While this has originally been conceived for the analysis of gamma-ray burst light (GRB) curves, its usage can be readily extended to other astrophysical transient phenomena, whose activity is recorded through different surveys. We tested and validated it through simulated featureless profiles as well as simulated GRB time profiles. We showcase the algorithm's potential by comparing with the popular algorithm by Li and Fenimore, that is frequently adopted in the literature. Thanks to its high flexibility, the mask of excess patterns used by MEPSA can be tailored and optimised to the kind of data to be analysed without modifying the code. The C code is made publicly available.

  1. A homotopy algorithm for synthesizing robust controllers for flexible structures via the maximum entropy design equations

    NASA Technical Reports Server (NTRS)

    Collins, Emmanuel G., Jr.; Richter, Stephen

    1990-01-01

    One well known deficiency of LQG compensators is that they do not guarantee any measure of robustness. This deficiency is especially highlighted when considering control design for complex systems such as flexible structures. There has thus been a need to generalize LQG theory to incorporate robustness constraints. Here we describe the maximum entropy approach to robust control design for flexible structures, a generalization of LQG theory, pioneered by Hyland, which has proved useful in practice. The design equations consist of a set of coupled Riccati and Lyapunov equations. A homotopy algorithm that is used to solve these design equations is presented.

  2. Flexible Job-Shop Scheduling with Dual-Resource Constraints to Minimize Tardiness Using Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Paksi, A. B. N.; Ma'ruf, A.

    2016-02-01

    In general, both machines and human resources are needed for processing a job on production floor. However, most classical scheduling problems have ignored the possible constraint caused by availability of workers and have considered only machines as a limited resource. In addition, along with production technology development, routing flexibility appears as a consequence of high product variety and medium demand for each product. Routing flexibility is caused by capability of machines that offers more than one machining process. This paper presents a method to address scheduling problem constrained by both machines and workers, considering routing flexibility. Scheduling in a Dual-Resource Constrained shop is categorized as NP-hard problem that needs long computational time. Meta-heuristic approach, based on Genetic Algorithm, is used due to its practical implementation in industry. Developed Genetic Algorithm uses indirect chromosome representative and procedure to transform chromosome into Gantt chart. Genetic operators, namely selection, elitism, crossover, and mutation are developed to search the best fitness value until steady state condition is achieved. A case study in a manufacturing SME is used to minimize tardiness as objective function. The algorithm has shown 25.6% reduction of tardiness, equal to 43.5 hours.

  3. Trajectory-Oriented Approach to Managing Traffic Complexity: Trajectory Flexibility Metrics and Algorithms and Preliminary Complexity Impact Assessment

    NASA Technical Reports Server (NTRS)

    Idris, Husni; Vivona, Robert A.; Al-Wakil, Tarek

    2009-01-01

    This document describes exploratory research on a distributed, trajectory oriented approach for traffic complexity management. The approach is to manage traffic complexity based on preserving trajectory flexibility and minimizing constraints. In particular, the document presents metrics for trajectory flexibility; a method for estimating these metrics based on discrete time and degree of freedom assumptions; a planning algorithm using these metrics to preserve flexibility; and preliminary experiments testing the impact of preserving trajectory flexibility on traffic complexity. The document also describes an early demonstration capability of the trajectory flexibility preservation function in the NASA Autonomous Operations Planner (AOP) platform.

  4. A flexible implementation for Doppler radar to verify various base-band array signal processing algorithms

    NASA Astrophysics Data System (ADS)

    Yang, Eunjung; Lee, Jonghyun; Jung, Byungwook; Chun, Joohwan

    2005-09-01

    We describe a flexible hardware system of the Doppler radar which is designed to verify various baseband array signal processing algorithms. In this work we design the Doppler radar system simulator for baseband signal processing in laboratory level. Based on this baseband signal processor, a PN-code pulse doppler radar simulator is developed. More specifically, this simulator consists of an echo signal generation part and a signal processing part. For the echo signal generation part, we use active array structure with 4 elements, and adopt baker coded PCM signal in transmission and reception for digital pulse compression. In the signal processing part, we first transform RF radar pulse to the baseband signal because we use the basebands algorithms using IF sampling. Various digital beamforming algorithms can be adopted as a baseband algorithm in our simulator. We mainly use Multiple Sidelobe Canceller (MSC) with main array antenna elements and auxiliary antenna elements as beamforming and sidelobe canceller algorithm. For Doppler filtering algorithms, we use the FFT. A control set is necessary to control overall system and to manage the timing schedule for the operation.

  5. Time-varying modal parameters identification of a spacecraft with rotating flexible appendage by recursive algorithm

    NASA Astrophysics Data System (ADS)

    Ni, Zhiyu; Mu, Ruinan; Xun, Guangbin; Wu, Zhigang

    2016-01-01

    The rotation of spacecraft flexible appendage may cause changes in modal parameters. For this time-varying system, the computation cost of the frequently-used singular value decomposition (SVD) identification method is high. Some control problems, such as the self-adaptive control, need the latest modal parameters to update the controller parameters in time. In this paper, the projection approximation subspace tracking (PAST) recursive algorithm is applied as an alternative method to identify the time-varying modal parameters. This method avoids the SVD by signal subspace projection and improves the computational efficiency. To verify the ability of this recursive algorithm in spacecraft modal parameters identification, a spacecraft model with rapid rotational appendage, Soil Moisture Active/Passive (SMAP) satellite, is established, and the time-varying modal parameters of the satellite are identified recursively by designing the input and output signals. The results illustrate that this recursive algorithm can obtain the modal parameters in the high signal noise ratio (SNR) and it has better computational efficiency than the SVD method. Moreover, to improve the identification precision of this recursive algorithm in the low SNR, the wavelet de-noising technology is used to decrease the effect of noises.

  6. Automatic design of decision-tree induction algorithms tailored to flexible-receptor docking data

    PubMed Central

    2012-01-01

    Background This paper addresses the prediction of the free energy of binding of a drug candidate with enzyme InhA associated with Mycobacterium tuberculosis. This problem is found within rational drug design, where interactions between drug candidates and target proteins are verified through molecular docking simulations. In this application, it is important not only to correctly predict the free energy of binding, but also to provide a comprehensible model that could be validated by a domain specialist. Decision-tree induction algorithms have been successfully used in drug-design related applications, specially considering that decision trees are simple to understand, interpret, and validate. There are several decision-tree induction algorithms available for general-use, but each one has a bias that makes it more suitable for a particular data distribution. In this article, we propose and investigate the automatic design of decision-tree induction algorithms tailored to particular drug-enzyme binding data sets. We investigate the performance of our new method for evaluating binding conformations of different drug candidates to InhA, and we analyze our findings with respect to decision tree accuracy, comprehensibility, and biological relevance. Results The empirical analysis indicates that our method is capable of automatically generating decision-tree induction algorithms that significantly outperform the traditional C4.5 algorithm with respect to both accuracy and comprehensibility. In addition, we provide the biological interpretation of the rules generated by our approach, reinforcing the importance of comprehensible predictive models in this particular bioinformatics application. Conclusions We conclude that automatically designing a decision-tree algorithm tailored to molecular docking data is a promising alternative for the prediction of the free energy from the binding of a drug candidate with a flexible-receptor. PMID:23171000

  7. Numerical algorithms for computations of feedback laws arising in control of flexible systems

    NASA Technical Reports Server (NTRS)

    Lasiecka, Irena

    1989-01-01

    Several continuous models will be examined, which describe flexible structures with boundary or point control/observation. Issues related to the computation of feedback laws are examined (particularly stabilizing feedbacks) with sensors and actuators located either on the boundary or at specific point locations of the structure. One of the main difficulties is due to the great sensitivity of the system (hyperbolic systems with unbounded control actions), with respect to perturbations caused either by uncertainty of the model or by the errors introduced in implementing numerical algorithms. Thus, special care must be taken in the choice of the appropriate numerical schemes which eventually lead to implementable finite dimensional solutions. Finite dimensional algorithms are constructed on a basis of a priority analysis of the properties of the original, continuous (infinite diversional) systems with the following criteria in mind: (1) convergence and stability of the algorithms and (2) robustness (reasonable insensitivity with respect to the unknown parameters of the systems). Examples with mixed finite element methods and spectral methods are provided.

  8. A genetic algorithm-based approach to flexible flow-line scheduling with variable lot sizes.

    PubMed

    Lee, I; Sikora, R; Shaw, M J

    1997-01-01

    Genetic algorithms (GAs) have been used widely for such combinatorial optimization problems as the traveling salesman problem (TSP), the quadratic assignment problem (QAP), and job shop scheduling. In all of these problems there is usually a well defined representation which GA's use to solve the problem. We present a novel approach for solving two related problems-lot sizing and sequencing-concurrently using GAs. The essence of our approach lies in the concept of using a unified representation for the information about both the lot sizes and the sequence and enabling GAs to evolve the chromosome by replacing primitive genes with good building blocks. In addition, a simulated annealing procedure is incorporated to further improve the performance. We evaluate the performance of applying the above approach to flexible flow line scheduling with variable lot sizes for an actual manufacturing facility, comparing it to such alternative approaches as pair wise exchange improvement, tabu search, and simulated annealing procedures. The results show the efficacy of this approach for flexible flow line scheduling. PMID:18255838

  9. Exploring the Pareto frontier using multisexual evolutionary algorithms: an application to a flexible manufacturing problem

    NASA Astrophysics Data System (ADS)

    Bonissone, Stefano R.; Subbu, Raj

    2002-12-01

    In multi-objective optimization (MOO) problems we need to optimize many possibly conflicting objectives. For instance, in manufacturing planning we might want to minimize the cost and production time while maximizing the product's quality. We propose the use of evolutionary algorithms (EAs) to solve these problems. Solutions are represented as individuals in a population and are assigned scores according to a fitness function that determines their relative quality. Strong solutions are selected for reproduction, and pass their genetic material to the next generation. Weak solutions are removed from the population. The fitness function evaluates each solution and returns a related score. In MOO problems, this fitness function is vector-valued, i.e. it returns a value for each objective. Therefore, instead of a global optimum, we try to find the Pareto-optimal or non-dominated frontier. We use multi-sexual EAs with as many genders as optimization criteria. We have created new crossover and gender assignment functions, and experimented with various parameters to determine the best setting (yielding the highest number of non-dominated solutions.) These experiments are conducted using a variety of fitness functions, and the algorithms are later evaluated on a flexible manufacturing problem with total cost and time minimization objectives.

  10. A hybrid algorithm optimization approach for machine loading problem in flexible manufacturing system

    NASA Astrophysics Data System (ADS)

    Kumar, Vijay M.; Murthy, ANN; Chandrashekara, K.

    2012-05-01

    The production planning problem of flexible manufacturing system (FMS) concerns with decisions that have to be made before an FMS begins to produce parts according to a given production plan during an upcoming planning horizon. The main aspect of production planning deals with machine loading problem in which selection of a subset of jobs to be manufactured and assignment of their operations to the relevant machines are made. Such problems are not only combinatorial optimization problems, but also happen to be non-deterministic polynomial-time-hard, making it difficult to obtain satisfactory solutions using traditional optimization techniques. In this paper, an attempt has been made to address the machine loading problem with objectives of minimization of system unbalance and maximization of throughput simultaneously while satisfying the system constraints related to available machining time and tool slot designing and using a meta-hybrid heuristic technique based on genetic algorithm and particle swarm optimization. The results reported in this paper demonstrate the model efficiency and examine the performance of the system with respect to measures such as throughput and system utilization.

  11. Input-output oriented computation algorithms for the control of large flexible structures

    NASA Technical Reports Server (NTRS)

    Minto, K. D.

    1989-01-01

    An overview is given of work in progress aimed at developing computational algorithms addressing two important aspects in the control of large flexible space structures; namely, the selection and placement of sensors and actuators, and the resulting multivariable control law design problem. The issue of sensor/actuator set selection is particularly crucial to obtaining a satisfactory control design, as clearly a poor choice will inherently limit the degree to which good control can be achieved. With regard to control law design, the researchers are driven by concerns stemming from the practical issues associated with eventual implementation of multivariable control laws, such as reliability, limit protection, multimode operation, sampling rate selection, processor throughput, etc. Naturally, the burden imposed by dealing with these aspects of the problem can be reduced by ensuring that the complexity of the compensator is minimized. Our approach to these problems is based on extensions to input/output oriented techniques that have proven useful in the design of multivariable control systems for aircraft engines. In particular, researchers are exploring the use of relative gain analysis and the condition number as a means of quantifying the process of sensor/actuator selection and placement for shape control of a large space platform.

  12. Study on sub-cycling algorithm for flexible multi-body system: stability analysis and numerical examples

    NASA Astrophysics Data System (ADS)

    Miao, J. C.; Zhu, P.; Shi, G. L.; Chen, G. L.

    2008-01-01

    Numerical stability is an important issue for any integral procedure. Since sub-cycling algorithm has been presented by Belytschko et al. (Comput Methods Appl Mech Eng 17/18: 259-275, 1979), various kinds of these integral procedures were developed in later 20 years and their stability were widely studied. However, on how to apply the sub-cycling to flexible multi-body dynamics (FMD) is still a lack of investigation up to now. A particular sub-cycling algorithm for the FMD based on the central difference method was introduced in detail in part I (Miao et al. in Comp Mech doi: 10.1007/s00466-007-0183-9) of this paper. Adopting an integral approximation operator method, stability of the presented algorithm is transformed to a generalized eigenvalue problem in the paper and is discussed by solving the problem later. Numerical examples are performed to verify the availability and efficiency of the algorithm further.

  13. A flexible and robust neural network IASI-NH3 retrieval algorithm

    NASA Astrophysics Data System (ADS)

    Whitburn, S.; Van Damme, M.; Clarisse, L.; Bauduin, S.; Heald, C. L.; Hadji-Lazaro, J.; Hurtmans, D.; Zondlo, M. A.; Clerbaux, C.; Coheur, P.-F.

    2016-06-01

    In this paper, we describe a new flexible and robust NH3 retrieval algorithm from measurements of the Infrared Atmospheric Sounding Interferometer (IASI). The method is based on the calculation of a spectral hyperspectral range index (HRI) and subsequent conversion to NH3 columns via a neural network. It is an extension of the method presented in Van Damme et al. (2014a) who used lookup tables (LUT) for the radiance-concentration conversion. The new method inherits the advantages of the LUT-based method while providing several significant improvements. These include the following: (1) Complete temperature and humidity vertical profiles can be accounted for. (2) Third-party NH3 vertical profile information can be used. (3) Reported positive biases of LUT retrieval are reduced, and finally (4) a full measurement uncertainty characterization is provided. A running theme in this study, related to item (2), is the importance of the assumed vertical NH3 profile. We demonstrate the advantages of allowing variable profile shapes in the retrieval. As an example, we analyze how the retrievals change when all NH3 is assumed to be confined to the boundary layer. We analyze different averaging procedures in use for NH3 in the literature, introduced to cope with the variable measurement sensitivity and derive global averaged distributions for the year 2013. A comparison with a GEOS-Chem modeled global distribution is also presented, showing a general good correspondence (within ±3 × 1015 molecules.cm-2) over most of the Northern Hemisphere. However, IASI finds mean columns about 1-1.5 × 1016 molecules.cm-2 (˜50-60%) lower than GEOS-Chem for India and the North China plain.

  14. Vibration control of a flexible clamped-clamped plate based on an improved FULMS algorithm and laser displacement measurement

    NASA Astrophysics Data System (ADS)

    Xie, Lingbo; Qiu, Zhi-cheng; Zhang, Xian-min

    2016-06-01

    This paper presents a novel active resonant vibration control experiment of a flexible clamped-clamped plate using an improved filtered-U least mean square (FULMS) algorithm and laser displacement measurement. Different from the widely used PZT sensors or acceleration transducers, the vibration of the flexible clamped-clamped plate is measured by a non-contact laser displacement measurement sensor with higher measurement accuracy and without additional load to the plate. The conventional FULMS algorithm often uses fixed step size and needs reference signal related to the external disturbance signal. However, the fixed step size method cannot obtain a fast convergence speed and it will result in a low residual error. Thus, a variable step size method is investigated. In addition, it is difficult to extract reference signal related to the vibration source directly in the practical application. Therefore, it is practically useful that a reference signal is constructed by both the controller parameters and the vibration residual signal. The experimental results demonstrate that the improved FULMS algorithm has better vibration control effect than the proportional derivative (PD) feedback control algorithm and the fixed step-size control algorithm.

  15. Genetic algorithm based active vibration control for a moving flexible smart beam driven by a pneumatic rod cylinder

    NASA Astrophysics Data System (ADS)

    Qiu, Zhi-cheng; Shi, Ming-li; Wang, Bin; Xie, Zhuo-wei

    2012-05-01

    A rod cylinder based pneumatic driving scheme is proposed to suppress the vibration of a flexible smart beam. Pulse code modulation (PCM) method is employed to control the motion of the cylinder's piston rod for simultaneous positioning and vibration suppression. Firstly, the system dynamics model is derived using Hamilton principle. Its standard state-space representation is obtained for characteristic analysis, controller design, and simulation. Secondly, a genetic algorithm (GA) is applied to optimize and tune the control gain parameters adaptively based on the specific performance index. Numerical simulations are performed on the pneumatic driving elastic beam system, using the established model and controller with tuned gains by GA optimization process. Finally, an experimental setup for the flexible beam driven by a pneumatic rod cylinder is constructed. Experiments for suppressing vibrations of the flexible beam are conducted. Theoretical analysis, numerical simulation and experimental results demonstrate that the proposed pneumatic drive scheme and the adopted control algorithms are feasible. The large amplitude vibration of the first bending mode can be suppressed effectively.

  16. A Search Algorithm for Generating Alternative Process Plans in Flexible Manufacturing System

    NASA Astrophysics Data System (ADS)

    Tehrani, Hossein; Sugimura, Nobuhiro; Tanimizu, Yoshitaka; Iwamura, Koji

    Capabilities and complexity of manufacturing systems are increasing and striving for an integrated manufacturing environment. Availability of alternative process plans is a key factor for integration of design, process planning and scheduling. This paper describes an algorithm for generation of alternative process plans by extending the existing framework of the process plan networks. A class diagram is introduced for generating process plans and process plan networks from the viewpoint of the integrated process planning and scheduling systems. An incomplete search algorithm is developed for generating and searching the process plan networks. The benefit of this algorithm is that the whole process plan network does not have to be generated before the search algorithm starts. This algorithm is applicable to large and enormous process plan networks and also to search wide areas of the network based on the user requirement. The algorithm can generate alternative process plans and to select a suitable one based on the objective functions.

  17. Study on sub-cycling algorithm for flexible multi-body system—integral theory and implementation flow chart

    NASA Astrophysics Data System (ADS)

    Miao, J. C.; Zhu, P.; Shi, G. L.; Chen, G. L.

    2008-01-01

    A sub-cycling integration algorithm (or named multi-time-steps integration algorithm), which has been successfully applied to FEM dynamical analysis, was firstly presented by Belytschko et al. (Comput Methods Appl Mech Eng 17/18:259-275, 1979). However, the problem of how to apply this type of algorithm to flexible multi-body dynamics (FMD) problems still lacks investigation up to now. Similar to the region-partitioning method used in FEM, this paper presents a central-difference-based sub-cycling integral method by decomposing the variables of an FMD equation into several groups and adopting different integral step sizes to each group of the variables. Based on the condensed form of an FMD equation, a group of common update formulae and a sub-step update formula, which constitute the sub-cycling together, are established in the paper. Furthermore, an implementation flowchart of the sub-cycling is presented. Stability of the sub-cycling will be analyzed and numerical examples will be performed to verify availability and precision of the sub-cycling in part II of the paper.

  18. Flexible algorithm for real-time convolution supporting dynamic event-related fMRI

    NASA Astrophysics Data System (ADS)

    Eaton, Brent L.; Frank, Randall J.; Bolinger, Lizann; Grabowski, Thomas J.

    2002-04-01

    An efficient algorithm for generation of the task reference function has been developed that allows real-time statistical analysis of fMRI data, within the framework of the general linear model, for experiments with event-related stimulus designs. By leveraging time-stamped data collection in the Input/Output time-aWare Architecture (I/OWA), we detect the onset time of a stimulus as it is delivered to a subject. A dynamically updated list of detected stimulus event times is maintained in shared memory as a data stream and delivered as input to a real-time convolution algorithm. As each image is acquired from the MR scanner, the time-stamp of its acquisition is delivered via a second dynamically updated stream to the convolution algorithm, where a running convolution of the events with an estimated hemodynamic response function is computed at the image acquisition time and written to a third stream in memory. Output is interpreted as the activation reference function and treated as the covariate of interest in the I/OWA implementation of the general linear model. Statistical parametric maps are computed and displayed to the I/OWA user interface in less than the time between successive image acquisitions.

  19. Non-recursive augmented Lagrangian algorithms for the forward and inverse dynamics of constrained flexible multibodies

    NASA Technical Reports Server (NTRS)

    Bayo, Eduardo; Ledesma, Ragnar

    1993-01-01

    A technique is presented for solving the inverse dynamics of flexible planar multibody systems. This technique yields the non-causal joint efforts (inverse dynamics) as well as the internal states (inverse kinematics) that produce a prescribed nominal trajectory of the end effector. A non-recursive global Lagrangian approach is used in formulating the equations for motion as well as in solving the inverse dynamics equations. Contrary to the recursive method previously presented, the proposed method solves the inverse problem in a systematic and direct manner for both open-chain as well as closed-chain configurations. Numerical simulation shows that the proposed procedure provides an excellent tracking of the desired end effector trajectory.

  20. Caseworker judgments and substantiation.

    PubMed

    Cross, Theodore P; Casanueva, Cecilia

    2009-02-01

    Substantiation can have an important effect on what interventions are pursued for children investigated for maltreatment, but researchers lack knowledge about how the decision to substantiate is made. Using information from 4,515 children from a national probability study of children investigated for maltreatment, this study examined how caseworker judgments of harm, risk, and evidence predicted substantiation. The substantiation rate was 29.9%, but the majority of cases were substantiated when caseworkers reported at least moderate harm, at least moderate risk, and/or probably to clearly sufficient evidence. Each judgment variable significantly predicted substantiation in a multivariable model, with evidence the strongest predictor. Child gender and age were significant predictors beyond harm, risk, and evidence, suggesting that other judgments also influence substantiation. In 9 of 100 cases, reports were not substantiated despite moderate to severe harm. Thus, substantiation is generally based on judgments of harm, risk, and evidence but not exclusively. The findings underline previous researchers' conclusions that substantiation is a flawed measure of child maltreatment and suggest that policy and practice related to substantiation are due for a fresh appraisal by state child welfare service agencies. PMID:18794302

  1. Algorithms for Efficient Computation of Transfer Functions for Large Order Flexible Systems

    NASA Technical Reports Server (NTRS)

    Maghami, Peiman G.; Giesy, Daniel P.

    1998-01-01

    An efficient and robust computational scheme is given for the calculation of the frequency response function of a large order, flexible system implemented with a linear, time invariant control system. Advantage is taken of the highly structured sparsity of the system matrix of the plant based on a model of the structure using normal mode coordinates. The computational time per frequency point of the new computational scheme is a linear function of system size, a significant improvement over traditional, still-matrix techniques whose computational times per frequency point range from quadratic to cubic functions of system size. This permits the practical frequency domain analysis of systems of much larger order than by traditional, full-matrix techniques. Formulations are given for both open- and closed-loop systems. Numerical examples are presented showing the advantages of the present formulation over traditional approaches, both in speed and in accuracy. Using a model with 703 structural modes, the present method was up to two orders of magnitude faster than a traditional method. The present method generally showed good to excellent accuracy throughout the range of test frequencies, while traditional methods gave adequate accuracy for lower frequencies, but generally deteriorated in performance at higher frequencies with worst case errors being many orders of magnitude times the correct values.

  2. The use of a multiobjective evolutionary algorithm to increase flexibility in the search for better IMRT plans

    PubMed Central

    Holdsworth, Clay; Kim, Minsun; Liao, Jay; Phillips, Mark

    2012-01-01

    Purpose: To evaluate how a more flexible and thorough multiobjective search of feasible IMRT plans affects performance in IMRT optimization. Methods: A multiobjective evolutionary algorithm (MOEA) was used as a tool to investigate how expanding the search space to include a wider range of penalty functions affects the quality of the set of IMRT plans produced. The MOEA uses a population of IMRT plans to generate new IMRT plans through deterministic minimization of recombined penalty functions that are weighted sums of multiple, tissue-specific objective functions. The quality of the generated plans are judged by an independent set of nonconvex, clinically relevant decision criteria, and all dominated plans are eliminated. As this process repeats itself, better plans are produced so that the population of IMRT plans will approach the Pareto front. Three different approaches were used to explore the effects of expanding the search space. First, the evolutionary algorithm used genetic optimization principles to search by simultaneously optimizing both the weights and tissue-specific dose parameters in penalty functions. Second, penalty function parameters were individually optimized for each voxel in all organs at risk (OARs) in the MOEA. Finally, a heuristic voxel-specific improvement (VSI) algorithm that can be used on any IMRT plan was developed that incrementally improves voxel-specific penalty function parameters for all structures (OARs and targets). Different approaches were compared using the concept of domination comparison applied to the sets of plans obtained by multiobjective optimization. Results: MOEA optimizations that simultaneously searched both importance weights and dose parameters generated sets of IMRT plans that were superior to sets of plans produced when either type of parameter was fixed for four example prostate plans. The amount of improvement increased with greater overlap between OARs and targets. Allowing the MOEA to search for voxel

  3. A fast algorithm for parabolic PDE-based inverse problems based on Laplace transforms and flexible Krylov solvers

    SciTech Connect

    Bakhos, Tania; Saibaba, Arvind K.; Kitanidis, Peter K.

    2015-10-15

    We consider the problem of estimating parameters in large-scale weakly nonlinear inverse problems for which the underlying governing equations is a linear, time-dependent, parabolic partial differential equation. A major challenge in solving these inverse problems using Newton-type methods is the computational cost associated with solving the forward problem and with repeated construction of the Jacobian, which represents the sensitivity of the measurements to the unknown parameters. Forming the Jacobian can be prohibitively expensive because it requires repeated solutions of the forward and adjoint time-dependent parabolic partial differential equations corresponding to multiple sources and receivers. We propose an efficient method based on a Laplace transform-based exponential time integrator combined with a flexible Krylov subspace approach to solve the resulting shifted systems of equations efficiently. Our proposed solver speeds up the computation of the forward and adjoint problems, thus yielding significant speedup in total inversion time. We consider an application from Transient Hydraulic Tomography (THT), which is an imaging technique to estimate hydraulic parameters related to the subsurface from pressure measurements obtained by a series of pumping tests. The algorithms discussed are applied to a synthetic example taken from THT to demonstrate the resulting computational gains of this proposed method.

  4. Active vibration reduction of a flexible structure bonded with optimised piezoelectric pairs using half and quarter chromosomes in genetic algorithms

    NASA Astrophysics Data System (ADS)

    Daraji, A. H.; Hale, J. M.

    2012-08-01

    The optimal placement of sensors and actuators in active vibration control is limited by the number of candidates in the search space. The search space of a small structure discretized to one hundred elements for optimising the location of ten actuators gives 1.73 × 1013 possible solutions, one of which is the global optimum. In this work, a new quarter and half chromosome technique based on symmetry is developed, by which the search space for optimisation of sensor/actuator locations in active vibration control of flexible structures may be greatly reduced. The technique is applied to the optimisation for eight and ten actuators located on a 500×500mm square plate, in which the search space is reduced by up to 99.99%. This technique helps for updating genetic algorithm program by updating natural frequencies and mode shapes in each generation to find the global optimal solution in a greatly reduced number of generations. An isotropic plate with piezoelectric sensor/actuator pairs bonded to its surface was investigated using the finite element method and Hamilton's principle based on first order shear deformation theory. The placement and feedback gain of ten and eight sensor/actuator pairs was optimised for a cantilever and clamped-clamped plate to attenuate the first six modes of vibration, using minimization of linear quadratic index as an objective function.

  5. Flexible, flexible and flexible

    SciTech Connect

    Blankinship, S.

    2009-02-15

    CFB plants are gaining a reputation for taking advantage of opportunity fuel while providing other substantial benefits. While dozens of pulverized coal projects face delay or cancellation amid uncertainty about the future of national policies regarding carbon capture among other issues, several CFB projects are moving forward in the US and elsewhere. The advances of CFB technology are discussed. Cleco Corp. is shifting from 70% gas and 30% coal to a 50/50 gas/coal mix using a 600 MW CFB in its Rodemacher 3 plant. The Virginia City Hybrid Energy Center will burn a mixture of 80% waste coal and 20% forestry wood chips in a CFB unit. Alstom is pursuing oxy-firing on the pulverised coal side with a 30 MW demonstration with Vattenfall in Germany. It is also pursuing the CFB side of oxy-fuel on a large scale. 1 photo.

  6. Establishing Substantial Equivalence: Transcriptomics

    NASA Astrophysics Data System (ADS)

    Baudo, María Marcela; Powers, Stephen J.; Mitchell, Rowan A. C.; Shewry, Peter R.

    Regulatory authorities in Western Europe require transgenic crops to be substantially equivalent to conventionally bred forms if they are to be approved for commercial production. One way to establish substantial equivalence is to compare the transcript profiles of developing grain and other tissues of transgenic and conventionally bred lines, in order to identify any unintended effects of the transformation process. We present detailed protocols for transcriptomic comparisons of developing wheat grain and leaf material, and illustrate their use by reference to our own studies of lines transformed to express additional gluten protein genes controlled by their own endosperm-specific promoters. The results show that the transgenes present in these lines (which included those encoding marker genes) did not have any significant unpredicted effects on the expression of endogenous genes and that the transgenic plants were therefore substantially equivalent to the corresponding parental lines.

  7. Establishing Substantial Equivalence: Metabolomics

    NASA Astrophysics Data System (ADS)

    Beale, Michael H.; Ward, Jane L.; Baker, John M.

    Modern ‘metabolomic’ methods allow us to compare levels of many structurally diverse compounds in an automated fashion across a large number of samples. This technology is ideally suited to screening of populations of plants, including trials where the aim is the determination of unintended effects introduced by GM. A number of metabolomic methods have been devised for the determination of substantial equivalence. We have developed a methodology, using [1H]-NMR fingerprinting, for metabolomic screening of plants and have applied it to the study of substantial equivalence of field-grown GM wheat. We describe here the principles and detail of that protocol as applied to the analysis of flour generated from field plots of wheat. Particular emphasis is given to the downstream data processing and comparison of spectra by multivariate analysis, from which conclusions regarding metabolome changes due to the GM can be assessed against the background of natural variation due to environment.

  8. Substantial evidence of effect.

    PubMed

    Gould, A Lawrence

    2002-02-01

    Pressures for rapid drug development, especially for treatments that may affect public health significantly, drive a need to reconsider what is necessary to establish the "substantial evidence" of efficacy and safety required for regulatory approval. The concept of substantial evidence of effect can be stated fairly simply in principle, but its application to the evaluation of findings from real clinical drug development programs can be quite complicated and depend on circumstances relating to the population studied and the condition being treated. This paper discusses a number of considerations that arise in attempting to address this issue. These include confirmation of efficacy/safety as opposed to replication of results, the use of surrogates for the clinical outcome, ethical considerations, the use of trials aimed at demonstrating equivalence or noninferiority instead of superiority of a new drug, and the balance between benefits and risks. Recent developments such as the International Conference on Harmonization (ICH) guidelines dealing with statistical principles and choice of control group, and Food and Drug Administration (FDA) guidances interpreting the 1998 Modernization Act identify useful alternative definitions of substantial evidence and also identify when a single study can be enough to demonstrate a clinically important effect. The primary difficulty with the use of noninferiority trials is the need to demonstrate assay sensitivity or validity, i.e., that the trial would have demonstrated the superiority of the active control treatment to placebo had the trial included a placebo group. Failure to demonstrate a significant difference between the presumed active treatments and an inactive control precludes a definitive conclusion of assay validity, but external evidence, e.g., from trials demonstrating the activity of the active control, may yet justify concluding that the trial was assay valid. Issues of interpretation of important unexpected

  9. Establishing Substantial Equivalence: Proteomics

    NASA Astrophysics Data System (ADS)

    Lovegrove, Alison; Salt, Louise; Shewry, Peter R.

    Wheat is a major crop in world agriculture and is consumed after processing into a range of food products. It is therefore of great importance to determine the consequences (intended and unintended) of transgenesis in wheat and whether genetically modified lines are substantially equivalent to those produced by conventional plant breeding. Proteomic analysis is one of several approaches which can be used to address these questions. Two-dimensional PAGE (2D PAGE) remains the most widely available method for proteomic analysis, but is notoriously difficult to reproduce between laboratories. We therefore describe methods which have been developed as standard operating procedures in our laboratory to ensure the reproducibility of proteomic analyses of wheat using 2D PAGE analysis of grain proteins.

  10. Criteria for substantiating claims.

    PubMed

    Aggett, Peter J

    2007-01-01

    Claims are used to support public health advocacy and marketing. Their evidence base is variable. Claims are made on (i) nutrient content, (ii) comparative merits, (iii) health benefits, and (iv) medical benefits. Experience with therapeutic agents has aided the development of recommendations for the substantiation of health claims for foods and food components, with which dietary supplements would be included. An EU Concerted Activity, Functional Food Science in Europe, suggested that such claims should be based on the general outcomes of 'enhanced function' and 'reduced risk of disease'. A further EU Concerted Activity, The Process for the Assessment of Scientific Support for Claims on Foods, proposed that the evidence base should provide: a characterization of the food or food component to which the claimed effect is attributed; human data, primarily from intervention studies that represent the target populations for the claim; a dose-response relationship: evidence of allowing for confounders including lifestyle, consumption patterns, background diet and food matrix; an appropriate duration for the study; a measure of compliance; and have adequate statistical power to test the hypothesis. When ideal endpoints are not easily accessible for measurement, validated and quality assured markers of the intermediate or final outcomes could be used, as long as their relationship is well characterized. Overall, the totality and coherence of published and unpublished evidence should be considered. Assessments for substantiation need expert judgement, weighting of the strength of the claim, and intelligent use of the criteria applied on an individual basis with respect both to gaps in knowledge and to any need for new knowledge and data. PMID:17913223

  11. Evaluation of Variable Refrigerant Flow Systems Performance and the Enhanced Control Algorithm on Oak Ridge National Laboratory s Flexible Research Platform

    SciTech Connect

    Im, Piljae; Munk, Jeffrey D; Gehl, Anthony C

    2015-06-01

    A research project “Evaluation of Variable Refrigerant Flow (VRF) Systems Performance and the Enhanced Control Algorithm on Oak Ridge National Laboratory’s (ORNL’s) Flexible Research Platform” was performed to (1) install and validate the performance of Samsung VRF systems compared with the baseline rooftop unit (RTU) variable-air-volume (VAV) system and (2) evaluate the enhanced control algorithm for the VRF system on the two-story flexible research platform (FRP) in Oak Ridge, Tennessee. Based on the VRF system designed by Samsung and ORNL, the system was installed from February 18 through April 15, 2014. The final commissioning and system optimization were completed on June 2, 2014, and the initial test for system operation was started the following day, June 3, 2014. In addition, the enhanced control algorithm was implemented and updated on June 18. After a series of additional commissioning actions, the energy performance data from the RTU and the VRF system were monitored from July 7, 2014, through February 28, 2015. Data monitoring and analysis were performed for the cooling season and heating season separately, and the calibrated simulation model was developed and used to estimate the energy performance of the RTU and VRF systems. This final report includes discussion of the design and installation of the VRF system, the data monitoring and analysis plan, the cooling season and heating season data analysis, and the building energy modeling study

  12. Piping Flexibility

    NASA Technical Reports Server (NTRS)

    1978-01-01

    A NASA computer program aids Hudson Engineering Corporation, Houston, Texas, in the design and construction of huge petrochemical processing plants like the one shown, which is located at Ju'aymah, Saudi Arabia. The pipes handling the flow of chemicals are subject to a variety of stresses, such as weight and variations in pressure and temperature. Hudson Engineering uses a COSMIC piping flexibility analysis computer program to analyze stresses and unsure the necessary strength and flexibility of the pipes. This program helps the company realize substantial savings in reduced engineering time.

  13. A flexibility-based method via the iterated improved reduction system and the cuckoo optimization algorithm for damage quantification with limited sensors

    NASA Astrophysics Data System (ADS)

    Zare Hosseinzadeh, Ali; Bagheri, Abdollah; Ghodrati Amiri, Gholamreza; Koo, Ki-Young

    2014-04-01

    In this paper, a novel and effective damage diagnosis algorithm is proposed to localize and quantify structural damage using incomplete modal data, considering the existence of some limitations in the number of attached sensors on structures. The damage detection problem is formulated as an optimization problem by computing static displacements in the reduced model of a structure subjected to a unique static load. The static responses are computed through the flexibility matrix of the damaged structure obtained based on the incomplete modal data of the structure. In the algorithm, an iterated improved reduction system method is applied to prepare an accurate reduced model of a structure. The optimization problem is solved via a new evolutionary optimization algorithm called the cuckoo optimization algorithm. The efficiency and robustness of the presented method are demonstrated through three numerical examples. Moreover, the efficiency of the method is verified by an experimental study of a five-story shear building structure on a shaking table considering only two sensors. The obtained damage identification results for the numerical and experimental studies show the suitable and stable performance of the proposed damage identification method for structures with limited sensors.

  14. Flexible Filter Bank Based on an Improved Weighted Overlap-Add Algorithm for Processing Wide Bandwidth Radio Astronomy Signals

    NASA Astrophysics Data System (ADS)

    Wang, Xianhai; Meng, Qiao; Han, J. L.; Liu, Wei; Zhang, Jianwei

    2015-12-01

    Wideband signals from a radio telescope have to be channelized for spectral observations or for dedispersion for pulsar observations. A polyphase filter bank is designed based on the improved weighted overlap-add (IWOLA) algorithm to achieve channelization. The IWOLA algorithm involves applying an equivalent Hilbert transform to the normal WOLA filter bank by shifting the center frequency of every sub-band by a half of the frequency bin, so that the IWOLA filter bank provides K independently output complex subbands instead of the usual K + 1 sub-bands, reducing the subsequent processing units by one set. Performance of the proposed IWOLA filter bank is analyzed by means of MATLAB simulations. We show how the IWOLA filter bank can be used for a two-stage, high-resolution spectrometer, with a much reduced consumption of FPGA on-chip block RAM.

  15. Ligand Docking to Intermediate and Close-To-Bound Conformers Generated by an Elastic Network Model Based Algorithm for Highly Flexible Proteins.

    PubMed

    Kurkcuoglu, Zeynep; Doruker, Pemra

    2016-01-01

    Incorporating receptor flexibility in small ligand-protein docking still poses a challenge for proteins undergoing large conformational changes. In the absence of bound structures, sampling conformers that are accessible by apo state may facilitate docking and drug design studies. For this aim, we developed an unbiased conformational search algorithm, by integrating global modes from elastic network model, clustering and energy minimization with implicit solvation. Our dataset consists of five diverse proteins with apo to complex RMSDs 4.7-15 Å. Applying this iterative algorithm on apo structures, conformers close to the bound-state (RMSD 1.4-3.8 Å), as well as the intermediate states were generated. Dockings to a sequence of conformers consisting of a closed structure and its "parents" up to the apo were performed to compare binding poses on different states of the receptor. For two periplasmic binding proteins and biotin carboxylase that exhibit hinge-type closure of two dynamics domains, the best pose was obtained for the conformer closest to the bound structure (ligand RMSDs 1.5-2 Å). In contrast, the best pose for adenylate kinase corresponded to an intermediate state with partially closed LID domain and open NMP domain, in line with recent studies (ligand RMSD 2.9 Å). The docking of a helical peptide to calmodulin was the most challenging case due to the complexity of its 15 Å transition, for which a two-stage procedure was necessary. The technique was first applied on the extended calmodulin to generate intermediate conformers; then peptide docking and a second generation stage on the complex were performed, which in turn yielded a final peptide RMSD of 2.9 Å. Our algorithm is effective in producing conformational states based on the apo state. This study underlines the importance of such intermediate states for ligand docking to proteins undergoing large transitions. PMID:27348230

  16. Ligand Docking to Intermediate and Close-To-Bound Conformers Generated by an Elastic Network Model Based Algorithm for Highly Flexible Proteins

    PubMed Central

    Kurkcuoglu, Zeynep; Doruker, Pemra

    2016-01-01

    Incorporating receptor flexibility in small ligand-protein docking still poses a challenge for proteins undergoing large conformational changes. In the absence of bound structures, sampling conformers that are accessible by apo state may facilitate docking and drug design studies. For this aim, we developed an unbiased conformational search algorithm, by integrating global modes from elastic network model, clustering and energy minimization with implicit solvation. Our dataset consists of five diverse proteins with apo to complex RMSDs 4.7–15 Å. Applying this iterative algorithm on apo structures, conformers close to the bound-state (RMSD 1.4–3.8 Å), as well as the intermediate states were generated. Dockings to a sequence of conformers consisting of a closed structure and its “parents” up to the apo were performed to compare binding poses on different states of the receptor. For two periplasmic binding proteins and biotin carboxylase that exhibit hinge-type closure of two dynamics domains, the best pose was obtained for the conformer closest to the bound structure (ligand RMSDs 1.5–2 Å). In contrast, the best pose for adenylate kinase corresponded to an intermediate state with partially closed LID domain and open NMP domain, in line with recent studies (ligand RMSD 2.9 Å). The docking of a helical peptide to calmodulin was the most challenging case due to the complexity of its 15 Å transition, for which a two-stage procedure was necessary. The technique was first applied on the extended calmodulin to generate intermediate conformers; then peptide docking and a second generation stage on the complex were performed, which in turn yielded a final peptide RMSD of 2.9 Å. Our algorithm is effective in producing conformational states based on the apo state. This study underlines the importance of such intermediate states for ligand docking to proteins undergoing large transitions. PMID:27348230

  17. Production of substantially pure fructose

    SciTech Connect

    Hatcher, H.J.; Gallian, J.J.; Leeper, S.A.

    1990-05-22

    This patent describes a process for the production of a substantially pure product containing greater than 60% fructose. It comprises: combining a sucrose-containing substrate with effective amounts of a levansucrase enzyme preparation to form levan and glucose; purifying the levan by at least one of the following purification methods: ultrafiltration, diafiltration, hyperfiltration, reverse osmosis, liquid--liquid partition, solvent extraction, chromatography, and precipitation; hydrolyzing the levan to form fructose substantially free of glucose and sucrose; and recovering the fructose by at least one of the following recovery methods: hyperfiltration, reverse osmosis, evaporation, drying, crystallization, and chromatography.

  18. Production of substantially pure fructose

    DOEpatents

    Hatcher, Herbert J.; Gallian, John J.; Leeper, Stephen A.

    1990-01-01

    A process is disclosed for the production of substantially pure fructose from sucrose-containing substrates. The process comprises converting the sucrose to levan and glucose, purifying the levan by membrane technology, hydrolyzing the levan to form fructose monomers, and recovering the fructose.

  19. Vcfanno: fast, flexible annotation of genetic variants.

    PubMed

    Pedersen, Brent S; Layer, Ryan M; Quinlan, Aaron R

    2016-01-01

    The integration of genome annotations is critical to the identification of genetic variants that are relevant to studies of disease or other traits. However, comprehensive variant annotation with diverse file formats is difficult with existing methods. Here we describe vcfanno, which flexibly extracts and summarizes attributes from multiple annotation files and integrates the annotations within the INFO column of the original VCF file. By leveraging a parallel "chromosome sweeping" algorithm, we demonstrate substantial performance gains by annotating ~85,000 variants per second with 50 attributes from 17 commonly used genome annotation resources. Vcfanno is available at https://github.com/brentp/vcfanno under the MIT license. PMID:27250555

  20. Design of a flexible component gathering algorithm for converting cell-based models to graph representations for use in evolutionary search

    PubMed Central

    2014-01-01

    Background The ability of science to produce experimental data has outpaced the ability to effectively visualize and integrate the data into a conceptual framework that can further higher order understanding. Multidimensional and shape-based observational data of regenerative biology presents a particularly daunting challenge in this regard. Large amounts of data are available in regenerative biology, but little progress has been made in understanding how organisms such as planaria robustly achieve and maintain body form. An example of this kind of data can be found in a new repository (PlanformDB) that encodes descriptions of planaria experiments and morphological outcomes using a graph formalism. Results We are developing a model discovery framework that uses a cell-based modeling platform combined with evolutionary search to automatically search for and identify plausible mechanisms for the biological behavior described in PlanformDB. To automate the evolutionary search we developed a way to compare the output of the modeling platform to the morphological descriptions stored in PlanformDB. We used a flexible connected component algorithm to create a graph representation of the virtual worm from the robust, cell-based simulation data. These graphs can then be validated and compared with target data from PlanformDB using the well-known graph-edit distance calculation, which provides a quantitative metric of similarity between graphs. The graph edit distance calculation was integrated into a fitness function that was able to guide automated searches for unbiased models of planarian regeneration. We present a cell-based model of planarian that can regenerate anatomical regions following bisection of the organism, and show that the automated model discovery framework is capable of searching for and finding models of planarian regeneration that match experimental data stored in PlanformDB. Conclusion The work presented here, including our algorithm for converting cell

  1. Synthesis of substantially monodispersed colloids

    NASA Technical Reports Server (NTRS)

    Klabunde, Kenneth J. (Inventor); Stoeva, Savka (Inventor); Sorensen, Christopher (Inventor)

    2003-01-01

    A method of forming ligated nanoparticles of the formula Y(Z).sub.x where Y is a nanoparticle selected from the group consisting of elemental metals having atomic numbers ranging from 21-34, 39-52, 57-83 and 89-102, all inclusive, the halides, oxides and sulfides of such metals, and the alkali metal and alkaline earth metal halides, and Z represents ligand moieties such as the alkyl thiols. In the method, a first colloidal dispersion is formed made up of nanoparticles solvated in a molar excess of a first solvent (preferably a ketone such as acetone), a second solvent different than the first solvent (preferably an organic aryl solvent such as toluene) and a quantity of ligand moieties; the first solvent is then removed under vacuum and the ligand moieties ligate to the nanoparticles to give a second colloidal dispersion of the ligated nanoparticles solvated in the second solvent. If substantially monodispersed nanoparticles are desired, the second dispersion is subjected to a digestive ripening process. Upon drying, the ligated nanoparticles may form a three-dimensional superlattice structure.

  2. Flexible multiply towpreg

    NASA Technical Reports Server (NTRS)

    Muzzy, John D. (Inventor); Varughese, Babu (Inventor)

    1992-01-01

    This invention relates to an improved flexible towpreg and a method of production therefor. The improved flexible towpreg comprises a plurality of towpreg plies which comprise reinforcing filaments and matrix forming material; the reinforcing filaments being substantially wetout by the matrix forming material such that the towpreg plies are substantially void-free composite articles, and the towpreg plies having an average thickness less than about 100 microns. The method of production for the improved flexible towpreg comprises the steps of spreading the reinforcing filaments to expose individually substantially all of the reinforcing filaments; coating the reinforcing filaments with the matrix forming material in a manner causing interfacial adhesion of the matrix forming material to the reinforcing filaments; forming the towpreg plies by heating the matrix forming material contacting the reinforcing filaments until the matrix forming material liquifies and coats the reinforcing filaments; and cooling the towpreg plies in a manner such that substantial cohesion between neighboring towpreg plies is prevented until the matrix forming material solidifies.

  3. 29 CFR 1990.145 - Consideration of substantial new issues or substantial new evidence.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... substance any substantial new issues upon which the Secretary did not reach a conclusion in the rulemaking... 29 Labor 9 2010-07-01 2010-07-01 false Consideration of substantial new issues or substantial new... of substantial new issues or substantial new evidence. (a) Substantial new issues....

  4. 29 CFR 1990.145 - Consideration of substantial new issues or substantial new evidence.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... substance any substantial new issues upon which the Secretary did not reach a conclusion in the rulemaking... 29 Labor 9 2011-07-01 2011-07-01 false Consideration of substantial new issues or substantial new... of substantial new issues or substantial new evidence. (a) Substantial new issues....

  5. Multi-Objective Trajectory Optimization by a Hierarchical Gradient Algorithm with Fuzzy Decision Logic —Application to Slew Maneuver Problems of a Flexible Space Structure—

    NASA Astrophysics Data System (ADS)

    Kojima, Hirohisa; Nakajima, Nobuyuki

    The rest-to-rest maneuver problem of a flexible space structure is a two-point boundary value problem (TPBVP) and is solved by some gradient methods. If TPBVP is strongly restricted by constraints, TBVP becomes an ill-defined problem, and the solution meeting all constraints cannot be obtained. However, reasonable suboptimal solutions are often needed since real plant systems are necessary to be controlled. In order to obtain such suboptimal solutions, we have developed a modified version of the hierarchy gradient method by installing fuzzy decision logic. Constraints are classified into non-fuzzy constraints and fuzzy constraints according to their priorities. Fuzzy constraints having a trade-off relationship with each other are compromised reasonably by fuzzy decision logic. The usefulness of the proposed method is numerically and experimentally verified by applying it to the rest-to-rest slew maneuver problem of a flexible space structure, where fuzzy constraints are final time, sensitivity of residual vibration energy with respect to the structure frequency uncertainty and maximum bending moment at the root of the flexible appendage.

  6. FLEXIBLE GEIGER COUNTER

    DOEpatents

    Richter, H.G.; Gillespie, A.S. Jr.

    1963-11-12

    A flexible Geiger counter constructed from materials composed of vinyl chloride polymerized with plasticizers or co-polymers is presented. The counter can be made either by attaching short segments of corrugated plastic sleeving together, or by starting with a length of vacuum cleaner hose composed of the above materials. The anode is maintained substantially axial Within the sleeving or hose during tube flexing by means of polystyrene spacer disks or an easily assembled polyethylene flexible cage assembly. The cathode is a wire spiraled on the outside of the counter. The sleeving or hose is fitted with glass end-pieces or any other good insulator to maintain the anode wire taut and to admit a counting gas mixture into the counter. Having the cathode wire on the outside of the counter substantially eliminates the objectional sheath effect of prior counters and permits counting rates up to 300,000 counts per minute. (AEC)

  7. Flexibility Program

    ERIC Educational Resources Information Center

    Connors, G. Patrick

    These brief guidelines for a muscular flexibility program state that the purpose of such a program is to increase the range of motion in order to avoid injuries and eliminate awkwardness in physical activities. A flexibility program is described as an extension of the warm-up period and should be an ongoing, permanent effort to lengthen muscles. A…

  8. Flexible Scheduling.

    ERIC Educational Resources Information Center

    Davis, Harold S.; Bechard, Joseph E.

    A flexible schedule allows teachers to change group size, group composition, and class length according to the purpose of the lesson. This pamphlet presents various "master" schedules for flexible scheduling: (1) Simple block schedules, (2) back-to-back schedules, (3) interdisciplinary schedules, (4) school-wide block schedules, (5) open-lab…

  9. Flexible spacecraft simulator

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Verification of control algorithms for flexible spacecraft can be done only through simulation and test; these are necessary to understand control/structure interaction (C/SI) sufficiently to design robust controllers for future spacecraft. The objective persued is to develop a low-cost facility which simulates the fundamental problem of C/SI; and to provide accessibility for designs so that experience can be gained in applying various multivariable control design methods to an actual structure. A test facility is being constructed with test elements that provide 3 rigid body and 6 flexible modes, all in the horizontal plane, with frequencies below 2.5 Hz. The control force actuator are on/off air jets with sensing by optical displacement sensors. Loop closure is provided by a digital computer with control algorithms designed using the IAC and MATRIX-X.

  10. 46 CFR 28.501 - Substantial alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Substantial alterations. 28.501 Section 28.501 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY UNINSPECTED VESSELS REQUIREMENTS FOR COMMERCIAL FISHING INDUSTRY VESSELS Stability § 28.501 Substantial alterations. (a) Except as provided in paragraph (b) of this section, a vessel that is...

  11. 40 CFR 725.94 - Substantiation requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CONTROL ACT REPORTING REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Confidentiality and Public... Inventory, the claim must be reasserted and substantiated at the time the Notice of Commencement (NOC) is... Inventory. (2) The submitter must substantiate the claim for confidentiality of the microorganism...

  12. 77 FR 39452 - Substantial Business Activities; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ..., June 12, 2012 (77 FR 34887) regarding whether a foreign corporation has substantial business activities...- 107889-12), which was the subject of FR. Doc. 2012-14238, is corrected as follows: On page 34887, column... Internal Revenue Service 26 CFR Part 1 RIN 1545-BK85 Substantial Business Activities; Correction...

  13. The development and assessment of a flexible inversion algorithm for aerosol property retrieval combining passive multiangle multispectral intensity and polarization measurements

    NASA Astrophysics Data System (ADS)

    Tsekeri, Alexandra; Gross, Barry; Moshary, Fred; Ahmed, Samir

    2009-08-01

    Quantifying aerosols on a global scale is extremely important due to their strong but anomalous impact on the global climate. Traditionally, the aerosols retrievals use only the intensity measurements of the scattered light. However, these measurements are less sensitive to aerosol type and also suffer contamination from ground surfaces. It is with these limitations in mind that we plan to improve the quality and scope of aerosol retrieval by making use of soon to be available polarimetric sensors such as the Aerosol Polarimetry Sensor (APS) on the GLORY satellite and combine them with other available datasets such as lidar data from the CALIPSO satellite for vertical profiling, and high-spatialcoverage intensity measurements from MODIS. To handle these extremely large sensor data sets, we will explore the capabilities of various statistical methods and even combine them to create inversion algorithms that will work best. Up to now, we worked with the simplest case, the single-scattering approximation and built a retrieval algorithm using multi-angular, multi-wavelength simulated measurements of intensity and polarization. The inversion techniques we used are the optimal estimator and the neural networks.

  14. Flexible cystoscopy.

    PubMed

    Kennedy, T J; Preminger, G M

    1988-08-01

    Flexible fiberoptic technology was first applied to cystoscopy in 1973, with greatly increased usage since 1982. Most procedures formerly performed with rigid cystoscopes can be done using flexible cystoscopes with minimal or no anesthesia. Patient positioning and precystocopy preparation and draping are simplified with the flexible fiberoptic instruments. Complete examination of the urethra and bladder can be performed with a single-lens system and with the patient in a variety of positions. Fiberoptic cystoscopy is limited in patients who are bleeding or have blood clots in their bladders. Withdrawal of irrigant or bladder drainage is cumbersome, and the fiberoptic image is currently not of the same caliber as that of the rigid-lens systems. Fiberoptic cystoscopy has become the procedure of choice for many urologists for ureteral stenting prior to extracorporeal shock-wave lithotripsy. With the advent of lithotripters that require no anesthesia, this application is likely to broaden. Future applications of flexible cystoscopy may include a flexible videocystoscope for use in diagnostic and therapeutic procedures. PMID:3407042

  15. Adaptive Control Strategies for Flexible Robotic Arm

    NASA Technical Reports Server (NTRS)

    Bialasiewicz, Jan T.

    1996-01-01

    The control problem of a flexible robotic arm has been investigated. The control strategies that have been developed have a wide application in approaching the general control problem of flexible space structures. The following control strategies have been developed and evaluated: neural self-tuning control algorithm, neural-network-based fuzzy logic control algorithm, and adaptive pole assignment algorithm. All of the above algorithms have been tested through computer simulation. In addition, the hardware implementation of a computer control system that controls the tip position of a flexible arm clamped on a rigid hub mounted directly on the vertical shaft of a dc motor, has been developed. An adaptive pole assignment algorithm has been applied to suppress vibrations of the described physical model of flexible robotic arm and has been successfully tested using this testbed.

  16. Optimal placement of sensors and actuators for active vibration reduction of a flexible structure using a genetic algorithm based on modified Hinfinity

    NASA Astrophysics Data System (ADS)

    Hale, J. M.; Daraji, A. H.

    2012-08-01

    This paper is concerned with active vibration reduction of a square isotropic plate, mounted rigidly along one edge to form a cantilever. Optimal placement of ten piezoelectric sensor/actuator pairs is investigated using a genetic algorithm to suppress the first six modes of vibration. A new objective function is developed based on modified Hinfinity to locate the sensor/actuator pairs. The plate, with piezoelectric sensor/actuator pairs bonded to its surfaces, is modelled using the finite element method and Hamilton's principle based on first order shear deformation theory including bending, membrane, and shear deformation effects. The effects of piezoelectric mass, stiffness and electromechanical coupling are taken into account. The first six natural frequencies are validated by comparison with the finite element ANSYS package using two dimensional SHELL63 and three dimensional SOLID45 elements and also experimentally. Vibration reduction for the cantilever plate with piezoelectric patches bonded in the optimal location was investigated to attenuate the first six modes of vibration using a linear optimal control scheme. The new fitness function has reduced the computational cost and given greater vibration reduction than other previously published results.

  17. Energy minimization on manifolds for docking flexible molecules

    PubMed Central

    Mirzaei, Hanieh; Zarbafian, Shahrooz; Villar, Elizabeth; Mottarella, Scott; Beglov, Dmitri; Vajda, Sandor; Paschalidis, Ioannis Ch.; Vakili, Pirooz; Kozakov, Dima

    2015-01-01

    In this paper we extend a recently introduced rigid body minimization algorithm, defined on manifolds, to the problem of minimizing the energy of interacting flexible molecules. The goal is to integrate moving the ligand in six dimensional rotational/translational space with internal rotations around rotatable bonds within the two molecules. We show that adding rotational degrees of freedom to the rigid moves of the ligand results in an overall optimization search space that is a manifold to which our manifold optimization approach can be extended. The effectiveness of the method is shown for three different docking problems of increasing complexity. First we minimize the energy of fragment-size ligands with a single rotatable bond as part of a protein mapping method developed for the identification of binding hot spots. Second, we consider energy minimization for docking a flexible ligand to a rigid protein receptor, an approach frequently used in existing methods. In the third problem we account for flexibility in both the ligand and the receptor. Results show that minimization using the manifold optimization algorithm is substantially more efficient than minimization using a traditional all-atom optimization algorithm while producing solutions of comparable quality. In addition to the specific problems considered, the method is general enough to be used in a large class of applications such as docking multidomain proteins with flexible hinges. The code is available under open source license (at http://cluspro.bu.edu/Code/Code_Rigtree.tar), and with minimal effort can be incorporated into any molecular modeling package. PMID:26478722

  18. 40 CFR 725.94 - Substantiation requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... microorganism identity confidential in the MCAN and wants the identity to be listed on the confidential... submitted under § 725.190. Otherwise, EPA will list the specific microorganism identity on the public Inventory. (2) The submitter must substantiate the claim for confidentiality of the microorganism...

  19. 40 CFR 725.94 - Substantiation requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Substantiation requirements. 725.94 Section 725.94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT REPORTING REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Confidentiality and Public Access to Information § 725.94...

  20. 40 CFR 725.94 - Substantiation requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... microorganism identity confidential in the MCAN and wants the identity to be listed on the confidential... submitted under § 725.190. Otherwise, EPA will list the specific microorganism identity on the public Inventory. (2) The submitter must substantiate the claim for confidentiality of the microorganism...

  1. 24 CFR 902.79 - Substantial default.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Notification of substantial default and response. If information from an annual assessment or audit, or any... substantively accurate; and (v) Notification to the PHA that, absent a satisfactory response in accordance with... determined to be an emergency, or in any case where the events or conditions precipitating the...

  2. Substantially oxygen-free contact tube

    NASA Technical Reports Server (NTRS)

    Pike, James F. (Inventor)

    1993-01-01

    A device for arc welding is provided in which a continuously-fed electrode wire is in electrical contact with a contact tube. The contact tube is improved by using a substantially oxygen-free conductive alloy in order to reduce the amount of electrical erosion.

  3. 21 CFR 514.4 - Substantial evidence.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... adequate and well-controlled studies, such as a study in a target species, study in laboratory animals... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS NEW ANIMAL DRUG APPLICATIONS General Provisions § 514.4 Substantial...

  4. 21 CFR 514.4 - Substantial evidence.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... effectiveness of the new animal drug involved that the new animal drug will have the effect it purports or is... have its intended effect. (b) Characteristics of substantial evidence—(1) Qualifications of experts... for use other than in animal feed or drinking water. (iii) Antibacterial with respect to a...

  5. 21 CFR 514.4 - Substantial evidence.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... effectiveness of the new animal drug involved that the new animal drug will have the effect it purports or is... have its intended effect. (b) Characteristics of substantial evidence—(1) Qualifications of experts... for use other than in animal feed or drinking water. (iii) Antibacterial with respect to a...

  6. Substantially Oxygen-Free Contact Tube

    NASA Technical Reports Server (NTRS)

    Pike, James F. (Inventor)

    1991-01-01

    A device for arc welding is provided in which a continuously-fed electrode wire is in electrical contact with a contact tube. The contact tube is improved by using a substantially oxygen-free conductive alloy in order to reduce the amount of electrical erosion.

  7. Pipelined Flexible Krylov Subspace Methods

    NASA Astrophysics Data System (ADS)

    Sanan, Patrick; Schnepp, Sascha M.; May, Dave A.

    2015-04-01

    State-of-the-art geophysical forward models expend most of their computational resources solving large, sparse linear systems. To date, preconditioned Krylov subspace methods have proven to be the only algorithmically scalable approach to solving these systems. However, at `extreme scale', the global reductions required by the inner products within these algorithms become a computational bottleneck, and it becomes advantageous to use pipelined Krylov subspace methods. These allow overlap of global reductions with other work, at the expense of using more storage and local computational effort, including overhead required to synchronize overlapping work. An impediment to using currently-available pipelined solvers for relevant geophysical forward modeling is that they are not `flexible', meaning that they cannot support nonlinear or varying preconditioners. Such preconditioners are effective for solving challenging linear systems, notably those arising from modelling of Stokes flow with highly heterogeneous viscosity structure. To this end, we introduce, for the first time, Krylov subspace methods which are both pipelined and flexible. We implement and demonstrate pipelined, flexible Conjugate Gradient, GMRES, and Conjugate Residual methods, which will be made publicly available via the open source PETSc library. Our algorithms are nontrivial modifications of the flexible methods they are based on (that is, they are not equivalent in exact arithmetic), so we analyze them mathematically and through a number of numerical experiments employing multi-level preconditioners. We highlight the benefits of these algorithms by solving variable viscosity Stokes problems directly relevant to lithospheric dynamics.

  8. Flexible ocean upwelling pipe

    DOEpatents

    Person, Abraham

    1980-01-01

    In an ocean thermal energy conversion facility, a cold water riser pipe is releasably supported at its upper end by the hull of the floating facility. The pipe is substantially vertical and has its lower end far below the hull above the ocean floor. The pipe is defined essentially entirely of a material which has a modulus of elasticity substantially less than that of steel, e.g., high density polyethylene, so that the pipe is flexible and compliant to rather than resistant to applied bending moments. The position of the lower end of the pipe relative to the hull is stabilized by a weight suspended below the lower end of the pipe on a flexible line. The pipe, apart from the weight, is positively buoyant. If support of the upper end of the pipe is released, the pipe sinks to the ocean floor, but is not damaged as the length of the line between the pipe and the weight is sufficient to allow the buoyant pipe to come to a stop within the line length after the weight contacts the ocean floor, and thereafter to float submerged above the ocean floor while moored to the ocean floor by the weight. The upper end of the pipe, while supported by the hull, communicates to a sump in the hull in which the water level is maintained below the ambient water level. The sump volume is sufficient to keep the pipe full during heaving of the hull, thereby preventing collapse of the pipe.

  9. Algorithms and Algorithmic Languages.

    ERIC Educational Resources Information Center

    Veselov, V. M.; Koprov, V. M.

    This paper is intended as an introduction to a number of problems connected with the description of algorithms and algorithmic languages, particularly the syntaxes and semantics of algorithmic languages. The terms "letter, word, alphabet" are defined and described. The concept of the algorithm is defined and the relation between the algorithm and…

  10. Contextual classification on a CDC Flexible Processor system. [for photomapped remote sensing data

    NASA Technical Reports Server (NTRS)

    Smith, B. W.; Siegel, H. J.; Swain, P. H.

    1981-01-01

    A potential hardware organization for the Flexible Processor Array is presented. An algorithm that implements a contextual classifier for remote sensing data analysis is given, along with uniprocessor classification algorithms. The Flexible Processor algorithm is provided, as are simulated timings for contextual classifiers run on the Flexible Processor Array and another system. The timings are analyzed for context neighborhoods of sizes three and nine.

  11. Does Pluto have a substantial atmosphere

    SciTech Connect

    Trafton, L.

    1980-01-01

    The presence of CH4 ice on Pluto implies that Pluto may have a substantial atmosphere consisting of heavy gases. Without such an atmosphere, sublimation of the CH4 ice would be so rapid on a cosmogonic time scale that either such an atmosphere would soon develop through the exposure of gases trapped in the CH4 ice or else the surface CH4 ice would soon be all sublimated away as other, more stable, ices became exposed. If such stable ices were present from the beginning, the existence of CH4 frosts would also imply that Pluto's present atmosphere contains a remnant of its primordial atmosphere.

  12. Highly porous ceramic oxide aerogels having improved flexibility

    NASA Technical Reports Server (NTRS)

    Meador, Mary Ann B. (Inventor); Nguyen, Baochau N. (Inventor); Guo, Haiquan (Inventor)

    2012-01-01

    Ceramic oxide aerogels having improved flexibility are disclosed. Preferred embodiments exhibit high modulus and other strength properties despite their improved flexibility. The gels may be polymer cross-linked via organic polymer chains to further improve strength properties, without substantially detracting from the improved flexibility. Methods of making such aerogels are also disclosed.

  13. FLEXIBLE COUPLING

    DOEpatents

    Babelay, E.F.

    1962-02-13

    A flexible shaft coupling for operation at speeds in excess of 14,000 rpm is designed which requires no lubrication. A driving sleeve member and a driven sleeve member are placed in concentric spaced relationship. A torque force is transmitted to the driven member from the driving member through a plurality of nylon balls symmetrically disposed between the spaced sleeves. The balls extend into races and recesses within the respective sleeve members. The sleeve members have a suitable clearance therebetween and the balls have a suitable radial clearance during operation of the coupling to provide a relatively loose coupling. These clearances accommodate for both parallel and/or angular misalignments and avoid metal-tometal contact between the sleeve members during operation. Thus, no lubrication is needed, and a minimum of vibrations is transmitted between the sleeve members. (AEC)

  14. Computation of the fuel optimal degree of controllability. [of large flexible spacecraft

    NASA Technical Reports Server (NTRS)

    Chen, Xin; Longman, Richard W.

    1990-01-01

    A new algorithm based on discretization is propposed which gives arbitrarily accurate results for fuel-optimal degree of controllability (DOC) as the discretization interval approaches zero. This research on DOC was motivated by the problem of optimizing the actuator locations in the control of large flexible spacecraft, but the concepts can also be applied to model reduction and as a measure of coupling between subsystems in hierarchical or decentralized control. The approach utilized is related closely to the time-optimal DOC algorithm; however, additional constraints must be applied, and a useful approach is found that avoids substantial increase in complexity. Algorithms are developed to calculate both the volume and the minimum distance to the boundary of the recovery region as the two choices of the controllability measure. Accurate methods for computation of both the time-optimal and fuel-optimal DOC for maneuver problems, are also described.

  15. Substantial bulk photovoltaic effect enhancement via nanolayering.

    PubMed

    Wang, Fenggong; Young, Steve M; Zheng, Fan; Grinberg, Ilya; Rappe, Andrew M

    2016-01-01

    Spontaneous polarization and inversion symmetry breaking in ferroelectric materials lead to their use as photovoltaic devices. However, further advancement of their applications are hindered by the paucity of ways of reducing bandgaps and enhancing photocurrent. By unravelling the correlation between ferroelectric materials' responses to solar irradiation and their local structure and electric polarization landscapes, here we show from first principles that substantial bulk photovoltaic effect enhancement can be achieved by nanolayering PbTiO3 with nickel ions and oxygen vacancies ((PbNiO2)x(PbTiO3)(1-x)). The enhancement of the total photocurrent for different spacings between the Ni-containing layers can be as high as 43 times due to a smaller bandgap and photocurrent direction alignment for all absorption energies. This is due to the electrostatic effect that arises from nanolayering. This opens up the possibility for control of the bulk photovoltaic effect in ferroelectric materials by nanoscale engineering of their structure and composition. PMID:26791545

  16. Substantial bulk photovoltaic effect enhancement via nanolayering

    PubMed Central

    Wang, Fenggong; Young, Steve M.; Zheng, Fan; Grinberg, Ilya; Rappe, Andrew M.

    2016-01-01

    Spontaneous polarization and inversion symmetry breaking in ferroelectric materials lead to their use as photovoltaic devices. However, further advancement of their applications are hindered by the paucity of ways of reducing bandgaps and enhancing photocurrent. By unravelling the correlation between ferroelectric materials' responses to solar irradiation and their local structure and electric polarization landscapes, here we show from first principles that substantial bulk photovoltaic effect enhancement can be achieved by nanolayering PbTiO3 with nickel ions and oxygen vacancies ((PbNiO2)x(PbTiO3)1−x). The enhancement of the total photocurrent for different spacings between the Ni-containing layers can be as high as 43 times due to a smaller bandgap and photocurrent direction alignment for all absorption energies. This is due to the electrostatic effect that arises from nanolayering. This opens up the possibility for control of the bulk photovoltaic effect in ferroelectric materials by nanoscale engineering of their structure and composition. PMID:26791545

  17. Substantial nitrogen pollution embedded in international trade

    NASA Astrophysics Data System (ADS)

    Oita, Azusa; Malik, Arunima; Kanemoto, Keiichiro; Geschke, Arne; Nishijima, Shota; Lenzen, Manfred

    2016-02-01

    Anthropogenic emissions of reactive nitrogen to the atmosphere and water bodies can damage human health and ecosystems. As a measure of a nation’s contribution to this potential damage, a country’s nitrogen footprint has been defined as the quantity of reactive nitrogen emitted during the production, consumption and transportation of commodities consumed within that country, whether those commodities are produced domestically or internationally. Here we use global emissions databases, a global nitrogen cycle model, and a global input-output database of domestic and international trade to calculate the nitrogen footprints for 188 countries as the sum of emissions of ammonia, nitrogen oxides and nitrous oxide to the atmosphere, and of nitrogen potentially exportable to water bodies. Per-capita footprints range from under 7 kg N yr-1 in some developing countries to over 100 kg N yr-1 in some wealthy nations. Consumption in China, India, the United States and Brazil is responsible for 46% of global emissions. Roughly a quarter of the global nitrogen footprint is from commodities that were traded across country borders. The main net exporters have significant agricultural, food and textile exports, and are often developing countries, whereas important net importers are almost exclusively developed economies. We conclude that substantial local nitrogen pollution is driven by demand from consumers in other countries.

  18. EARLY CHILDHOOD INVESTMENTS SUBSTANTIALLY BOOST ADULT HEALTH

    PubMed Central

    Campbell, Frances; Conti, Gabriella; Heckman, James J.; Moon, Seong Hyeok; Pinto, Rodrigo; Pungello, Elizabeth; Pan, Yi

    2014-01-01

    High-quality early childhood programs have been shown to have substantial benefits in reducing crime, raising earnings, and promoting education. Much less is known about their benefits for adult health. We report the long-term health impacts of one of the oldest and most heavily cited early childhood interventions with long-term follow-up evaluated by the method of randomization: the Carolina Abecedarian Project (ABC). Using recently collected biomedical data, we find that disadvantaged children randomly assigned to treatment have significantly lower prevalence of risk factors for cardiovascular and metabolic diseases in their mid-30s. The evidence is especially strong for males. The mean systolic blood pressure among the control males is 143, while only 126 among the treated. One in four males in the control group is affected by metabolic syndrome, while none in the treatment group is. To reach these conclusions, we address several statistical challenges. We use exact permutation tests to account for small sample sizes and conduct a parallel bootstrap confidence interval analysis to confirm the permutation analysis. We adjust inference to account for the multiple hypotheses tested and for nonrandom attrition. Our evidence shows the potential of early life interventions for preventing disease and promoting health. PMID:24675955

  19. Substantial bulk photovoltaic effect enhancement via nanolayering

    DOE PAGESBeta

    Wang, Fenggong; Young, Steve M.; Zheng, Fan; Grinberg, Ilya; Rappe, Andrew M.

    2016-01-21

    Spontaneous polarization and inversion symmetry breaking in ferroelectric materials lead to their use as photovoltaic devices. However, further advancement of their applications are hindered by the paucity of ways of reducing bandgaps and enhancing photocurrent. By unravelling the correlation between ferroelectric materials’ responses to solar irradiation and their local structure and electric polarization landscapes, here we show from first principles that substantial bulk photovoltaic effect enhancement can be achieved by nanolayering PbTiO3 with nickel ions and oxygen vacancies ((PbNiO2)x(PbTiO3)1–x). The enhancement of the total photocurrent for different spacings between the Ni-containing layers can be as high as 43 times duemore » to a smaller bandgap and photocurrent direction alignment for all absorption energies. This is due to the electrostatic effect that arises from nanolayering. Lastly, this opens up the possibility for control of the bulk photovoltaic effect in ferroelectric materials by nanoscale engineering of their structure and composition.« less

  20. Gasdynamic substantiation of physical theory of meteors

    NASA Astrophysics Data System (ADS)

    Egorova, Lidia A.; Tirskiy, Grigoriy A.

    2014-12-01

    Physical theory of meteors developing since 30s of the last century, based on two ordinary differential equations: the equation of motion for the center of mass of meteoroid and equation of meteoroid ablation. These equations contain drag and heat transfer coefficients, which are share of momentum and energy transferred from gas to meteoroid and effective enthalpy of mass loss. Accounting for different values of these coefficients substantially changes meteoroid ballistics compared with the results of simple physical theory of meteors. For the drag coefficient a simple interpolation formula is valid for all flow regimes and depends on the Reynolds number. The heat transfer coefficient represented in the form of the approximation depending on density and meteoroid radius. Based on the law of conservation of mass and energy at the front of meteoroid melting and evaporation the explicit expression for the effective enthalpy of mass loss Q was obtained, depending on the speed of the meteoroid and heterogeneous reactions on the surface. Classical solution gives a significant deviation from the exact one obtained in present study for small bodies (1 mm) at high altitudes and high speeds.

  1. Flexible weapons architecture design

    NASA Astrophysics Data System (ADS)

    Pyant, William C., III

    Present day air-delivered weapons are of a closed architecture, with little to no ability to tailor the weapon for the individual engagement. The closed architectures require weaponeers to make the target fit the weapon instead of fitting the individual weapons to a target. The concept of a flexible weapons aims to modularize weapons design using an open architecture shell into which different modules are inserted to achieve the desired target fractional damage while reducing cost and civilian casualties. This thesis shows that the architecture design factors of damage mechanism, fusing, weapons weight, guidance, and propulsion are significant in enhancing weapon performance objectives, and would benefit from modularization. Additionally, this thesis constructs an algorithm that can be used to design a weapon set for a particular target class based on these modular components.

  2. 20 CFR 220.141 - Substantial gainful activity, defined.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... activities like taking care of one's self, household tasks, hobbies, therapy, school attendance, club...) Substantial work activity. Substantial work activity is work activity that involves doing significant...

  3. 20 CFR 220.141 - Substantial gainful activity, defined.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... activities like taking care of one's self, household tasks, hobbies, therapy, school attendance, club...) Substantial work activity. Substantial work activity is work activity that involves doing significant...

  4. 20 CFR 220.141 - Substantial gainful activity, defined.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... activities like taking care of one's self, household tasks, hobbies, therapy, school attendance, club...) Substantial work activity. Substantial work activity is work activity that involves doing significant...

  5. 20 CFR 220.141 - Substantial gainful activity, defined.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... activities like taking care of one's self, household tasks, hobbies, therapy, school attendance, club...) Substantial work activity. Substantial work activity is work activity that involves doing significant...

  6. 20 CFR 220.141 - Substantial gainful activity, defined.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... activities like taking care of one's self, household tasks, hobbies, therapy, school attendance, club...) Substantial work activity. Substantial work activity is work activity that involves doing significant...

  7. Spatial operator algebra for flexible multibody dynamics

    NASA Technical Reports Server (NTRS)

    Jain, A.; Rodriguez, G.

    1993-01-01

    This paper presents an approach to modeling the dynamics of flexible multibody systems such as flexible spacecraft and limber space robotic systems. A large number of degrees of freedom and complex dynamic interactions are typical in these systems. This paper uses spatial operators to develop efficient recursive algorithms for the dynamics of these systems. This approach very efficiently manages complexity by means of a hierarchy of mathematical operations.

  8. Antenna pointing of large flexible telecommunications spacecraft

    NASA Technical Reports Server (NTRS)

    Govin, B.; Bousquet, A.

    1985-01-01

    Attitude control problems for large flexible telecommunications spacecraft were investigated. A typical S/C configuration is described and modeled by modal data derived from a finite element analysis. The effect of structural flexibility on radio-frequency sensor is analyzed. Model reduction using modal gain considerations is applied. Two control concepts are investigated: separate central body and antenna pointing control using direct feedback laws, centralized control using modal observer and optimal control. Performances of each concept and the algorithm implementation are assessed.

  9. Numerical stability analysis of the pseudo-spectral analytical time-domain PIC algorithm

    SciTech Connect

    Godfrey, Brendan B.; Vay, Jean-Luc; Haber, Irving

    2014-02-01

    The pseudo-spectral analytical time-domain (PSATD) particle-in-cell (PIC) algorithm solves the vacuum Maxwell's equations exactly, has no Courant time-step limit (as conventionally defined), and offers substantial flexibility in plasma and particle beam simulations. It is, however, not free of the usual numerical instabilities, including the numerical Cherenkov instability, when applied to relativistic beam simulations. This paper derives and solves the numerical dispersion relation for the PSATD algorithm and compares the results with corresponding behavior of the more conventional pseudo-spectral time-domain (PSTD) and finite difference time-domain (FDTD) algorithms. In general, PSATD offers superior stability properties over a reasonable range of time steps. More importantly, one version of the PSATD algorithm, when combined with digital filtering, is almost completely free of the numerical Cherenkov instability for time steps (scaled to the speed of light) comparable to or smaller than the axial cell size.

  10. 20 CFR 404.1675 - Finding of substantial failure.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Finding of substantial failure. 404.1675... DISABILITY INSURANCE (1950- ) Determinations of Disability Substantial Failure § 404.1675 Finding of substantial failure. A finding of substantial failure with respect to a State may not be made unless and...

  11. 20 CFR 416.1075 - Finding of substantial failure.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Finding of substantial failure. 416.1075... AGED, BLIND, AND DISABLED Determinations of Disability Substantial Failure § 416.1075 Finding of substantial failure. A finding of substantial failure with respect to a State may not be made unless and...

  12. 20 CFR 404.1675 - Finding of substantial failure.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Finding of substantial failure. 404.1675... DISABILITY INSURANCE (1950- ) Determinations of Disability Substantial Failure § 404.1675 Finding of substantial failure. A finding of substantial failure with respect to a State may not be made unless and...

  13. 20 CFR 416.1075 - Finding of substantial failure.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Finding of substantial failure. 416.1075... AGED, BLIND, AND DISABLED Determinations of Disability Substantial Failure § 416.1075 Finding of substantial failure. A finding of substantial failure with respect to a State may not be made unless and...

  14. 20 CFR 404.1675 - Finding of substantial failure.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Finding of substantial failure. 404.1675... DISABILITY INSURANCE (1950- ) Determinations of Disability Substantial Failure § 404.1675 Finding of substantial failure. A finding of substantial failure with respect to a State may not be made unless and...

  15. 20 CFR 416.1075 - Finding of substantial failure.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Finding of substantial failure. 416.1075... AGED, BLIND, AND DISABLED Determinations of Disability Substantial Failure § 416.1075 Finding of substantial failure. A finding of substantial failure with respect to a State may not be made unless and...

  16. 20 CFR 404.1675 - Finding of substantial failure.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Finding of substantial failure. 404.1675... DISABILITY INSURANCE (1950- ) Determinations of Disability Substantial Failure § 404.1675 Finding of substantial failure. A finding of substantial failure with respect to a State may not be made unless and...

  17. 20 CFR 416.1075 - Finding of substantial failure.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Finding of substantial failure. 416.1075... AGED, BLIND, AND DISABLED Determinations of Disability Substantial Failure § 416.1075 Finding of substantial failure. A finding of substantial failure with respect to a State may not be made unless and...

  18. 20 CFR 404.1675 - Finding of substantial failure.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Finding of substantial failure. 404.1675... DISABILITY INSURANCE (1950- ) Determinations of Disability Substantial Failure § 404.1675 Finding of substantial failure. A finding of substantial failure with respect to a State may not be made unless and...

  19. Large planar maneuvers for articulated flexible manipulators

    NASA Technical Reports Server (NTRS)

    Huang, Jen-Kuang; Yang, Li-Farn

    1988-01-01

    An articulated flexible manipulator carried on a translational cart is maneuvered by an active controller to perform certain position control tasks. The nonlinear dynamics of the articulated flexible manipulator are derived and a transformation matrix is formulated to localize the nonlinearities within the inertia matrix. Then a feedback linearization scheme is introduced to linearize the dynamic equations for controller design. Through a pole placement technique, a robust controller design is obtained by properly assigning a set of closed-loop desired eigenvalues to meet performance requirements. Numerical simulations for the articulated flexible manipulators are given to demonstrate the feasibility and effectiveness of the proposed position control algorithms.

  20. Adaptive path planning for flexible manufacturing

    SciTech Connect

    Chen, Pang C.

    1994-08-01

    Path planning needs to be fast to facilitate real-time robot programming. Unfortunately, current planning techniques are still too slow to be effective, as they often require several minutes, if not hours of computation. To overcome this difficulty, we present an adaptive algorithm that uses past experience to speed up future performance. It is a learning algorithm suitable for automating flexible manufacturing in incrementally-changing environments. The algorithm allows the robot to adapt to its environment by having two experience manipulation schemes: For minor environmental change, we use an object-attached experience abstraction scheme to increase the flexibility of the learned experience; for major environmental change, we use an on-demand experience repair scheme to retain those experiences that remain valid and useful. Using this algorithm, we can effectively reduce the overall robot planning time by re-using the computation result for one task to plan a path for another.

  1. Image enhancement algorithm based on improved lateral inhibition network

    NASA Astrophysics Data System (ADS)

    Yun, Haijiao; Wu, Zhiyong; Wang, Guanjun; Tong, Gang; Yang, Hua

    2016-05-01

    There is often substantial noise and blurred details in the images captured by cameras. To solve this problem, we propose a novel image enhancement algorithm combined with an improved lateral inhibition network. Firstly, we built a mathematical model of a lateral inhibition network in conjunction with biological visual perception; this model helped to realize enhanced contrast and improved edge definition in images. Secondly, we proposed that the adaptive lateral inhibition coefficient adhere to an exponential distribution thus making the model more flexible and more universal. Finally, we added median filtering and a compensation measure factor to build the framework with high pass filtering functionality thus eliminating image noise and improving edge contrast, addressing problems with blurred image edges. Our experimental results show that our algorithm is able to eliminate noise and the blurring phenomena, and enhance the details of visible and infrared images.

  2. Flexible high-speed CODEC

    NASA Technical Reports Server (NTRS)

    Segallis, Greg P.; Wernlund, Jim V.; Corry, Glen

    1993-01-01

    This report is prepared by Harris Government Communication Systems Division for NASA Lewis Research Center under contract NAS3-25087. It is written in accordance with SOW section 4.0 (d) as detailed in section 2.6. The purpose of this document is to provide a summary of the program, performance results and analysis, and a technical assessment. The purpose of this program was to develop a flexible, high-speed CODEC that provides substantial coding gain while maintaining bandwidth efficiency for use in both continuous and bursted data environments for a variety of applications.

  3. The Nature and Substantiation of Official Sexual Abuse Reports.

    ERIC Educational Resources Information Center

    Eckenrode, John; And Others

    1988-01-01

    A sample of 796 New York sexual abuse reports was studied to explore factors associated with substantiation of the reports following an investigation. Substantiation rates increased with the child's age, and reports were more likely to be substantiated when they involved female children or came from a mandated source. (Author/JDD)

  4. 24 CFR 907.3 - Bases for substantial default.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Bases for substantial default. 907.3 Section 907.3 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT... DEVELOPMENT SUBSTANTIAL DEFAULT BY A PUBLIC HOUSING AGENCY § 907.3 Bases for substantial default....

  5. 19 CFR 10.7 - Substantial containers or holders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Substantial containers or holders. 10.7 Section 10... Exported and Returned § 10.7 Substantial containers or holders. (a) Substantial containers or holders... domestic products exported and returned. When such containers or holders are imported not containing...

  6. 29 CFR 825.218 - Substantial and grievous economic injury.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Substantial and grievous economic injury. 825.218 Section... Medical Leave Act § 825.218 Substantial and grievous economic injury. (a) In order to deny restoration to... cause “substantial and grievous economic injury” to the operations of the employer, not whether...

  7. 29 CFR 825.218 - Substantial and grievous economic injury.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Substantial and grievous economic injury. 825.218 Section... Medical Leave Act § 825.218 Substantial and grievous economic injury. (a) In order to deny restoration to... cause “substantial and grievous economic injury” to the operations of the employer, not whether...

  8. 29 CFR 825.218 - Substantial and grievous economic injury.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Substantial and grievous economic injury. 825.218 Section... Medical Leave Act § 825.218 Substantial and grievous economic injury. (a) In order to deny restoration to... cause “substantial and grievous economic injury” to the operations of the employer, not whether...

  9. 29 CFR 825.218 - Substantial and grievous economic injury.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Substantial and grievous economic injury. 825.218 Section... Medical Leave Act § 825.218 Substantial and grievous economic injury. (a) In order to deny restoration to... cause substantial and grievous economic injury to the operations of the employer, not whether...

  10. 29 CFR 825.218 - Substantial and grievous economic injury.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Substantial and grievous economic injury. 825.218 Section... Medical Leave Act § 825.218 Substantial and grievous economic injury. (a) In order to deny restoration to... cause substantial and grievous economic injury to the operations of the employer, not whether...

  11. Flexibility and Muscular Strength.

    ERIC Educational Resources Information Center

    Liemohn, Wendell

    1988-01-01

    This definition of flexibility and muscular strength also explores their roles in overall physical fitness and focuses on how increased flexibility and muscular strength can help decrease or eliminate lower back pain. (CB)

  12. SPS flexible system control assessment analysis

    NASA Technical Reports Server (NTRS)

    Balas, M. J.

    1981-01-01

    Active control of the Satellite Power System (SPS0, a large mechanically flexible aerospace structure is addressed. The control algorithm is the principle component in the feedback link from sensors to actuators. An analysis of the interaction of the SPS structure and its active control system is presented.

  13. Carbon Nanotube Flexible and Stretchable Electronics

    NASA Astrophysics Data System (ADS)

    Cai, Le; Wang, Chuan

    2015-08-01

    The low-cost and large-area manufacturing of flexible and stretchable electronics using printing processes could radically change people's perspectives on electronics and substantially expand the spectrum of potential applications. Examples range from personalized wearable electronics to large-area smart wallpapers and from interactive bio-inspired robots to implantable health/medical apparatus. Owing to its one-dimensional structure and superior electrical property, carbon nanotube is one of the most promising material platforms for flexible and stretchable electronics. Here in this paper, we review the recent progress in this field. Applications of single-wall carbon nanotube networks as channel semiconductor in flexible thin-film transistors and integrated circuits, as stretchable conductors in various sensors, and as channel material in stretchable transistors will be discussed. Lastly, state-of-the-art advancement on printing process, which is ideal for large-scale fabrication of flexible and stretchable electronics, will also be reviewed in detail.

  14. Carbon Nanotube Flexible and Stretchable Electronics.

    PubMed

    Cai, Le; Wang, Chuan

    2015-12-01

    The low-cost and large-area manufacturing of flexible and stretchable electronics using printing processes could radically change people's perspectives on electronics and substantially expand the spectrum of potential applications. Examples range from personalized wearable electronics to large-area smart wallpapers and from interactive bio-inspired robots to implantable health/medical apparatus. Owing to its one-dimensional structure and superior electrical property, carbon nanotube is one of the most promising material platforms for flexible and stretchable electronics. Here in this paper, we review the recent progress in this field. Applications of single-wall carbon nanotube networks as channel semiconductor in flexible thin-film transistors and integrated circuits, as stretchable conductors in various sensors, and as channel material in stretchable transistors will be discussed. Lastly, state-of-the-art advancement on printing process, which is ideal for large-scale fabrication of flexible and stretchable electronics, will also be reviewed in detail. PMID:26264684

  15. PHURBAS: AN ADAPTIVE, LAGRANGIAN, MESHLESS, MAGNETOHYDRODYNAMICS CODE. I. ALGORITHM

    SciTech Connect

    Maron, Jason L.; McNally, Colin P.; Mac Low, Mordecai-Mark E-mail: cmcnally@amnh.org

    2012-05-01

    We present an algorithm for simulating the equations of ideal magnetohydrodynamics and other systems of differential equations on an unstructured set of points represented by sample particles. Local, third-order, least-squares, polynomial interpolations (Moving Least Squares interpolations) are calculated from the field values of neighboring particles to obtain field values and spatial derivatives at the particle position. Field values and particle positions are advanced in time with a second-order predictor-corrector scheme. The particles move with the fluid, so the time step is not limited by the Eulerian Courant-Friedrichs-Lewy condition. Full spatial adaptivity is implemented to ensure the particles fill the computational volume, which gives the algorithm substantial flexibility and power. A target resolution is specified for each point in space, with particles being added and deleted as needed to meet this target. Particle addition and deletion is based on a local void and clump detection algorithm. Dynamic artificial viscosity fields provide stability to the integration. The resulting algorithm provides a robust solution for modeling flows that require Lagrangian or adaptive discretizations to resolve. This paper derives and documents the Phurbas algorithm as implemented in Phurbas version 1.1. A following paper presents the implementation and test problem results.

  16. Principles of Flexible Protein-Protein Docking

    PubMed Central

    Andrusier, Nelly; Mashiach, Efrat; Nussinov, Ruth; Wolfson, Haim J.

    2008-01-01

    Treating flexibility in molecular docking is a major challenge in cell biology research. Here we describe the background and the principles of existing flexible protein-protein docking methods, focusing on the algorithms and their rational. We describe how protein flexibility is treated in different stages of the docking process: in the preprocessing stage, rigid and flexible parts are identified and their possible conformations are modeled. This preprocessing provides information for the subsequent docking and refinement stages. In the docking stage, an ensemble of pre-generated conformations or the identified rigid domains may be docked separately. In the refinement stage, small-scale movements of the backbone and side-chains are modeled and the binding orientation is improved by rigid-body adjustments. For clarity of presentation, we divide the different methods into categories. This should allow the reader to focus on the most suitable method for a particular docking problem. PMID:18655061

  17. 49 CFR 384.301 - Substantial compliance-general requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 CFR 383.123 not later than September 30, 2006. (c) A State must come into substantial compliance... statutes, regulations, administrative procedures and practices, organizational structures, internal...

  18. 49 CFR 384.301 - Substantial compliance-general requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., organizational structures, internal control mechanisms, resource assignments (facilities, equipment, and... come into substantial compliance with 49 CFR 383.123 not later than September 30, 2006. (c) A...

  19. 49 CFR 384.301 - Substantial compliance-general requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., organizational structures, internal control mechanisms, resource assignments (facilities, equipment, and... come into substantial compliance with 49 CFR 383.123 not later than September 30, 2006. (c) A...

  20. 49 CFR 384.301 - Substantial compliance-general requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., organizational structures, internal control mechanisms, resource assignments (facilities, equipment, and... come into substantial compliance with 49 CFR 383.123 not later than September 30, 2006. (c) A...

  1. 49 CFR 384.301 - Substantial compliance-general requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., organizational structures, internal control mechanisms, resource assignments (facilities, equipment, and... come into substantial compliance with 49 CFR 383.123 not later than September 30, 2006. (c) A...

  2. The Constitution of the Human Embryo as Substantial Change.

    PubMed

    Alvargonzález, David

    2016-04-01

    This paper analyzes the transformation from the human zygote to the implanted embryo under the prism of substantial change. After a brief introduction, it vindicates the Aristotelian ideas of substance and accident, and those of substantial and accidental change. It then claims that the transformation from the multicelled zygote to the implanted embryo amounts to a substantial change. Pushing further, it contends that this substantial change cannot be explained following patterns of genetic reductionism, emergence, and self-organization, and proposes Gustavo Bueno's idea of anamorphosis as a means to encapsulate criticism against such positions. PMID:26850033

  3. MILSTAR's flexible substrate solar array: Lessons learned, addendum

    NASA Technical Reports Server (NTRS)

    Gibb, John

    1990-01-01

    MILSTAR's Flexible Substrate Solar Array (FSSA) is an evolutionary development of the lightweight, flexible substrate design pioneered at Lockheed during the seventies. Many of the features of the design are related to the Solar Array Flight Experiment (SAFE), flown on STS-41D in 1984. FSSA development has created a substantial technology base for future flexible substrate solar arrays such as the array for the Space Station Freedom. Lessons learned during the development of the FSSA can and should be applied to the Freedom array and other future flexible substrate designs.

  4. A decoupled recursive approach for constrained flexible multibody system dynamics

    NASA Technical Reports Server (NTRS)

    Lai, Hao-Jan; Kim, Sung-Soo; Haug, Edward J.; Bae, Dae-Sung

    1989-01-01

    A variational-vector calculus approach is employed to derive a recursive formulation for dynamic analysis of flexible multibody systems. Kinematic relationships for adjacent flexible bodies are derived in a companion paper, using a state vector notation that represents translational and rotational components simultaneously. Cartesian generalized coordinates are assigned for all body and joint reference frames, to explicitly formulate deformation kinematics under small deformation kinematics and an efficient flexible dynamics recursive algorithm is developed. Dynamic analysis of a closed loop robot is performed to illustrate efficiency of the algorithm.

  5. 19 CFR 134.35 - Articles substantially changed by manufacture.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Articles substantially changed by manufacture. 134...; DEPARTMENT OF THE TREASURY COUNTRY OF ORIGIN MARKING Exceptions to Marking Requirements § 134.35 Articles substantially changed by manufacture. (a) Articles other than goods of a NAFTA country. An article used in...

  6. 40 CFR Appendix C to Part 112 - Substantial Harm Criteria

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Substantial Harm Criteria C Appendix C to Part 112 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS OIL POLLUTION PREVENTION Pt. 112, App. C Appendix C to Part 112—Substantial Harm Criteria 1.0Introduction The flowchart provided in Attachment C-I...

  7. 40 CFR Appendix C to Part 112 - Substantial Harm Criteria

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Substantial Harm Criteria C Appendix C to Part 112 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS OIL POLLUTION PREVENTION Pt. 112, App. C Appendix C to Part 112—Substantial Harm Criteria 1.0Introduction The flowchart provided in Attachment C-I...

  8. 40 CFR Appendix C to Part 112 - Substantial Harm Criteria

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Substantial Harm Criteria C Appendix C to Part 112 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS OIL POLLUTION PREVENTION Pt. 112, App. C Appendix C to Part 112—Substantial Harm Criteria 1.0Introduction The flowchart provided in Attachment C-I...

  9. 40 CFR Appendix C to Part 112 - Substantial Harm Criteria

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Substantial Harm Criteria C Appendix C to Part 112 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS OIL POLLUTION PREVENTION Pt. 112, App. C Appendix C to Part 112—Substantial Harm Criteria 1.0Introduction The flowchart provided in Attachment C-I...

  10. 40 CFR Appendix C to Part 112 - Substantial Harm Criteria

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 23 2013-07-01 2013-07-01 false Substantial Harm Criteria C Appendix C to Part 112 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS OIL POLLUTION PREVENTION Pt. 112, App. C Appendix C to Part 112—Substantial Harm Criteria 1.0Introduction The flowchart provided in Attachment C-I...

  11. 26 CFR 1.528-4 - Substantiality test.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 7 2014-04-01 2013-04-01 true Substantiality test. 1.528-4 Section 1.528-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Homeowners Associations § 1.528-4 Substantiality test. (a) In general. In...

  12. 19 CFR 134.35 - Articles substantially changed by manufacture.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Articles substantially changed by manufacture. 134...; DEPARTMENT OF THE TREASURY COUNTRY OF ORIGIN MARKING Exceptions to Marking Requirements § 134.35 Articles substantially changed by manufacture. (a) Articles other than goods of a NAFTA country. An article used in...

  13. 19 CFR 134.35 - Articles substantially changed by manufacture.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Articles substantially changed by manufacture. 134... substantially changed by manufacture. (a) Articles other than goods of a NAFTA country. An article used in the United States in manufacture which results in an article having a name, character, or use differing...

  14. 19 CFR 134.35 - Articles substantially changed by manufacture.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Articles substantially changed by manufacture. 134... substantially changed by manufacture. (a) Articles other than goods of a NAFTA country. An article used in the United States in manufacture which results in an article having a name, character, or use differing...

  15. 19 CFR 134.35 - Articles substantially changed by manufacture.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Articles substantially changed by manufacture. 134... substantially changed by manufacture. (a) Articles other than goods of a NAFTA country. An article used in the United States in manufacture which results in an article having a name, character, or use differing...

  16. 20 CFR 627.477 - Governor's determination of substantial violation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Governor's determination of substantial... Standards § 627.477 Governor's determination of substantial violation. (a) Except as provided at paragraph (d) of this section, if, as a result of financial and compliance audits or otherwise, the...

  17. Differentiating between substantiated, suspected, and unsubstantiated maltreatment in Canada.

    PubMed

    Trocmé, Nico; Knoke, Della; Fallon, Barbara; MacLaurin, Bruce

    2009-02-01

    The decision to substantiate is a key factor in determining eligibility for services and decisions to press criminal charges or to remove a child, and it is frequently the basis for selecting samples of maltreated children or to measure recidivism or intervention effectiveness. Although there is a growing body of research on case substantiation in the United States, few studies have examined this decision in other jurisdictions. Using data from the 2003 Canadian Incidence Study of Reported Child Abuse and Neglect, this study examines the profiles of a national sample of 10,010 investigations. Multivariate analyses reveal that substantiation decisions are generally made in a fashion that is relatively consistent with the clinical characteristics of cases. Along with severity of harm, parent risk factors, and housing risk factors, police referrals are among the most important predictors of case substantiation. Cases involving multiple forms of maltreatment are also more likely to be substantiated. PMID:18710956

  18. Recursive dynamics for flexible multibody systems using spatial operators

    NASA Technical Reports Server (NTRS)

    Jain, A.; Rodriguez, G.

    1990-01-01

    Due to their structural flexibility, spacecraft and space manipulators are multibody systems with complex dynamics and possess a large number of degrees of freedom. Here the spatial operator algebra methodology is used to develop a new dynamics formulation and spatially recursive algorithms for such flexible multibody systems. A key feature of the formulation is that the operator description of the flexible system dynamics is identical in form to the corresponding operator description of the dynamics of rigid multibody systems. A significant advantage of this unifying approach is that it allows ideas and techniques for rigid multibody systems to be easily applied to flexible multibody systems. The algorithms use standard finite-element and assumed modes models for the individual body deformation. A Newton-Euler Operator Factorization of the mass matrix of the multibody system is first developed. It forms the basis for recursive algorithms such as for the inverse dynamics, the computation of the mass matrix, and the composite body forward dynamics for the system. Subsequently, an alternative Innovations Operator Factorization of the mass matrix, each of whose factors is invertible, is developed. It leads to an operator expression for the inverse of the mass matrix, and forms the basis for the recursive articulated body forward dynamics algorithm for the flexible multibody system. For simplicity, most of the development here focuses on serial chain multibody systems. However, extensions of the algorithms to general topology flexible multibody systems are described. While the computational cost of the algorithms depends on factors such as the topology and the amount of flexibility in the multibody system, in general, it appears that in contrast to the rigid multibody case, the articulated body forward dynamics algorithm is the more efficient algorithm for flexible multibody systems containing even a small number of flexible bodies. The variety of algorithms described

  19. Fuzzy Control of Flexible-Link Manipulators: A Review

    NASA Technical Reports Server (NTRS)

    Akbarzadeh-T, M.-R.; Quintana, S.; Jamshidi, M.

    1998-01-01

    Several recent research efforts are reviewed here which have applied fuzzy logic in control of flexible-link manipulators. A flexible robot is a distributed parameter system represented by complex nonlinear dynamics, its actuator and the control parameters are non-colocated, and lastly, unstructured/unknown parameters play a significant role in model dynamics of a flexible robot operating in the real world. As a result, control of flexible robots is considered a promising area for application of intelligent control methodologies such as fuzzy logic, genetic algorithms, and neural networks.

  20. Genetic algorithms

    NASA Technical Reports Server (NTRS)

    Wang, Lui; Bayer, Steven E.

    1991-01-01

    Genetic algorithms are mathematical, highly parallel, adaptive search procedures (i.e., problem solving methods) based loosely on the processes of natural genetics and Darwinian survival of the fittest. Basic genetic algorithms concepts are introduced, genetic algorithm applications are introduced, and results are presented from a project to develop a software tool that will enable the widespread use of genetic algorithm technology.

  1. Recursive flexible multibody system dynamics using spatial operators

    NASA Technical Reports Server (NTRS)

    Jain, A.; Rodriguez, G.

    1992-01-01

    This paper uses spatial operators to develop new spatially recursive dynamics algorithms for flexible multibody systems. The operator description of the dynamics is identical to that for rigid multibody systems. Assumed-mode models are used for the deformation of each individual body. The algorithms are based on two spatial operator factorizations of the system mass matrix. The first (Newton-Euler) factorization of the mass matrix leads to recursive algorithms for the inverse dynamics, mass matrix evaluation, and composite-body forward dynamics for the systems. The second (innovations) factorization of the mass matrix, leads to an operator expression for the mass matrix inverse and to a recursive articulated-body forward dynamics algorithm. The primary focus is on serial chains, but extensions to general topologies are also described. A comparison of computational costs shows that the articulated-body, forward dynamics algorithm is much more efficient than the composite-body algorithm for most flexible multibody systems.

  2. Flexibility, Is That All?

    ERIC Educational Resources Information Center

    Renes, Wim M.

    This paper discusses the design of flexible and intelligent library buildings. The first section addresses how flexibility, as one of the requirements of a library building, that has high priority in the planning process. Intelligent libraries are considered in the second section, and functionality is stressed. The third section examines…

  3. Shear flexibility for structures

    NASA Technical Reports Server (NTRS)

    Stangeland, Maynard L. (Inventor)

    1976-01-01

    This device comprises a flexible sheet member having cross convolutions oriented 45.degree. to the shear vector with spherical reliefs at the convolution junctions. The spherical reliefs are essential to the shear flexibility by interrupting the principal stress lines that act along the ridges of the convolutions. The spherical reliefs provide convolutions in both directions in the plane of the cross-convolution ridges.

  4. Shear flexibility for structures

    NASA Technical Reports Server (NTRS)

    Stangeland, Maynard L. (Inventor)

    1977-01-01

    This device comprises a flexible sheet member having cross convolutions oriented 45.degree. to the shear vector with spherical reliefs at the convolution junctions. The spherical reliefs are essential to the shear flexibility by interrupting the principal stress lines that act along the ridges of the convolutions. The spherical reliefs provide convolutions in both directions in the plane of the cross-convolution ridges.

  5. Flexible Learning Opportunities.

    ERIC Educational Resources Information Center

    Further Education Unit, London (England).

    One way for colleges to meet the demand for a wider range of learning opportunities for adults in Great Britain is to provide more flexibility within the further education system. The concept of flexible learning involves the modification of delivery systems, specific providing agencies, target populations, specific determinants such as geographic…

  6. Flexible Heat Pipe

    NASA Technical Reports Server (NTRS)

    Bienert, W. B.; Wolf, D. A.

    1985-01-01

    Narrow Tube carries 10 watts or more to moving parts. Heat pipe 12 inches long and diameter of 0.312 inch (7.92mm). Bent to minimum radius of 2.5 blocks. Flexible section made of 321 stainless steel tubing (Cajon Flexible Tubing or equivalent). Evaporator and condenser made of oxygen free copper. Working fluid methanol.

  7. Flexible Animation Computer Program

    NASA Technical Reports Server (NTRS)

    Stallcup, Scott S.

    1990-01-01

    FLEXAN (Flexible Animation), computer program animating structural dynamics on Evans and Sutherland PS300-series graphics workstation with VAX/VMS host computer. Typical application is animation of spacecraft undergoing structural stresses caused by thermal and vibrational effects. Displays distortions in shape of spacecraft. Program displays single natural mode of vibration, mode history, or any general deformation of flexible structure. Written in FORTRAN 77.

  8. Flexibility within Fidelity

    ERIC Educational Resources Information Center

    Kendall, Philip C.; Gosch, Elizabeth; Furr, Jami M.; Sood, Erica

    2008-01-01

    The authors address concerns regarding manual-based treatments, highlighting the role of flexibility and creativity. A cognitive-behavioral therapy for youth anxiety called the Coping Cat program demonstrates the flexible application of manuals and emphasizes the importance of a child-centered, personalized approach that involves the child in the…

  9. Shield For Flexible Pipe

    NASA Technical Reports Server (NTRS)

    Ponton, Michael K.; Williford, Clifford B.; Lagen, Nicholas T.

    1995-01-01

    Cylindrical shield designed to fit around flexible pipe to protect nearby workers from injury and equipment from damage if pipe ruptures. Designed as pressure-relief device. Absorbs impact of debris ejected radially from broken flexible pipe. Also redirects flow of pressurized fluid escaping from broken pipe onto flow path allowing for relief of pressure while minimizing potential for harm.

  10. PredyFlexy: flexibility and local structure prediction from sequence

    PubMed Central

    de Brevern, Alexandre G.; Bornot, Aurélie; Craveur, Pierrick; Etchebest, Catherine; Gelly, Jean-Christophe

    2012-01-01

    Protein structures are necessary for understanding protein function at a molecular level. Dynamics and flexibility of protein structures are also key elements of protein function. So, we have proposed to look at protein flexibility using novel methods: (i) using a structural alphabet and (ii) combining classical X-ray B-factor data and molecular dynamics simulations. First, we established a library composed of structural prototypes (LSPs) to describe protein structure by a limited set of recurring local structures. We developed a prediction method that proposes structural candidates in terms of LSPs and predict protein flexibility along a given sequence. Second, we examine flexibility according to two different descriptors: X-ray B-factors considered as good indicators of flexibility and the root mean square fluctuations, based on molecular dynamics simulations. We then define three flexibility classes and propose a method based on the LSP prediction method for predicting flexibility along the sequence. This method does not resort to sophisticate learning of flexibility but predicts flexibility from average flexibility of predicted local structures. The method is implemented in PredyFlexy web server. Results are similar to those obtained with the most recent, cutting-edge methods based on direct learning of flexibility data conducted with sophisticated algorithms. PredyFlexy can be accessed at http://www.dsimb.inserm.fr/dsimb_tools/predyflexy/. PMID:22689641

  11. 26 CFR 1.507-6 - Substantial contributor defined.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... taxable years. Status as a substantial contributor, however, will date from the time when the donor first... October 9, 1969, H (W's spouse at the time of the 1941 gift) is considered to have made such...

  12. 26 CFR 1.274-5 - Substantiation requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 3 2011-04-01 2011-04-01 false Substantiation requirements. 1.274-5 Section 1.274-5 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Not Deductible § 1.274-5 Substantiation requirements. (a)-(b) . For further guidance, see § 1.274-5T(a) and...

  13. Adaptive control strategies for flexible robotic arm

    NASA Technical Reports Server (NTRS)

    Bialasiewicz, Jan T.

    1993-01-01

    The motivation of this research came about when a neural network direct adaptive control scheme was applied to control the tip position of a flexible robotic arm. Satisfactory control performance was not attainable due to the inherent non-minimum phase characteristics of the flexible robotic arm tip. Most of the existing neural network control algorithms are based on the direct method and exhibit very high sensitivity if not unstable closed-loop behavior. Therefore a neural self-tuning control (NSTC) algorithm is developed and applied to this problem and showed promising results. Simulation results of the NSTC scheme and the conventional self-tuning (STR) control scheme are used to examine performance factors such as control tracking mean square error, estimation mean square error, transient response, and steady state response.

  14. Control of nonlinear flexible space structures

    NASA Astrophysics Data System (ADS)

    Shi, Jianjun

    With the advances made in computer technology and efficiency of numerical algorithms over last decade, the MPC strategies have become quite popular among control community. However, application of MPC or GPC to flexible space structure control has not been explored adequately in the literature. The work presented in this thesis primarily focuses on application of GPC to control of nonlinear flexible space structures. This thesis is particularly devoted to the development of various approximate dynamic models, design and assessment of candidate controllers, and extensive numerical simulations for a realistic multibody flexible spacecraft, namely, Jupiter Icy Moons Orbiter (JIMO)---a Prometheus class of spacecraft proposed by NASA for deep space exploratory missions. A stable GPC algorithm is developed for Multi-Input-Multi-Output (MIMO) systems. An end-point weighting (penalty) is used in the GPC cost function to guarantee the nominal stability of the closed-loop system. A method is given to compute the desired end-point state from the desired output trajectory. The methodologies based on Fake Algebraic Riccati Equation (FARE) and constrained nonlinear optimization, are developed for synthesis of state weighting matrix. This makes this formulation more practical. A stable reconfigurable GPC architecture is presented and its effectiveness is demonstrated on both aircraft as well as spacecraft model. A representative in-orbit maneuver is used for assessing the performance of various control strategies using various design models. Different approximate dynamic models used for analysis include linear single body flexible structure, nonlinear single body flexible structure, and nonlinear multibody flexible structure. The control laws evaluated include traditional GPC, feedback linearization-based GPC (FLGPC), reconfigurable GPC, and nonlinear dissipative control. These various control schemes are evaluated for robust stability and robust performance in the presence of

  15. Rolling cuff flexible bellows

    DOEpatents

    Lambert, Donald R.

    1985-01-01

    A flexible connector apparatus used to join two stiff non-deformable members, such as piping. The apparatus is provided with one or more flexible sections or assemblies each utilizing a bellows of a rolling cuff type connected between two ridge members, with the bellows being supported by a back-up ring, such that only the curved end sections of the bellows are unsupported. Thus, the bellows can be considered as being of a tube-shaped configuration and thus have high pressure resistance. The components of the flexible apparatus are sealed or welded one to another such that it is fluid tight.

  16. Rolling cuff flexible bellows

    SciTech Connect

    Lambert, D. R.

    1985-09-10

    A flexible connector apparatus used to join two stiff non-deformable members, such as piping. The apparatus is provided with one or more flexible sections or assemblies each utilizing a bellows of a rolling cuff type connected between two ridge members, with the bellows being supported by a back-up ring, such that only the curved end sections of the bellows are unsupported. Thus, the bellows can be considered as being of a tube-shaped configuration and thus have high pressure resistance. The components of the flexible apparatus are sealed or welded one to another such that it is fluid tight.

  17. Measuring Substantial Reduction in Functioning in Patients with CFS

    PubMed Central

    Jason, Leonard A.; Brown, Molly; Evans, Meredyth; Anderson, Valerie; Lerch, Athena; Brown, Abigail; Hunnell, Jessica; Porter, Nicole

    2011-01-01

    Purpose All of the major current case definitions for chronic fatigue syndrome (CFS) specify substantial reductions in previous levels of occupational, educational, social, or personal activities to meet criteria. Difficulties have been encountered in operationalizing “substantial reductions.” For example, the Medical Outcomes Study Short Form-36 Health Survey (SF-36) has been used to determine whether individuals met the CFS disability criterion. However, previous methods of using the SF-36 have been prone to including people without substantial reductions in key areas of physical functioning when diagnosing CFS. This study sought to empirically identify the most appropriate SF-36 subscales for measuring substantial reductions in patients with CFS. Method The SF-36 was administered to two samples of patients with CFS: one recruited from tertiary care and the other a community-based sample; as well as a non-fatigued control group. Receiver operating characteristics were used to determine optimal cutoff scores for identifying patients with CFS. Results The SF-36 Role-Emotional subscale had the worst sensitivity and specificity, whereas the Vitality, Role-Physical, and Social Functioning subscales had the best sensitivity and specificity. Conclusion Based on evidence from this study, potential criteria for defining substantial reductions in functioning and diagnosing CFS is provided. PMID:20617920

  18. Flexibility in insulin prescription

    PubMed Central

    Kalra, Sanjay; Gupta, Yashdeep; Unnikrishnan, Ambika Gopalakrishnan

    2016-01-01

    This communication explores the concept of flexibility, a propos insulin preparations and insulin regimes used in the management of type 2 diabetes. The flexibility of an insulin regime or preparation is defined as their ability to be injected at variable times, with variable injection-meal time gaps, in a dose frequency and quantum determined by shared decision making, with a minimal requirement of glucose monitoring and health professional consultation, with no compromise on safety, efficiency and tolerability. The relative flexibility of various basal, prandial and dual action insulins, as well as intensive regimes, is compared. The biopsychosocial model of health is used to assess the utility of different insulins while encouraging a philosophy of flexible insulin usage. PMID:27186563

  19. Modeling flexible active nematics

    NASA Astrophysics Data System (ADS)

    Varga, Michael; Selinger, Robin

    We study active nematic phases of self-propelled flexible chains in two dimensions using computer simulation, to investigate effects of chain flexibility. In a ``dry'' phase of self-propelled flexible chains, we find that increasing chain stiffness enhances orientational order and correlation length, narrows the distribution of turning angles, increases persistence length, and increases the magnitude of giant density fluctuations. We further adapt the simulation model to describe behavior of microtubules driven by kinesin molecular motors in two different environments: on a rigid substrate with kinesin immobilized on the surface; and on a lipid membrane where kinesin is bonded to lipid head groups and can diffuse. Results are compared to experiments by L. Hirst and J. Xu. Lastly, we consider active nematics of flexible particles enclosed in soft, deformable encapsulation in two dimensions, and demonstrate novel mechanisms of pattern formation that are fundamentally different from those observed in bulk. Supported by NSF-DMR 1409658.

  20. Composite flexible blanket insulation

    NASA Technical Reports Server (NTRS)

    Kourtides, Demetrius A. (Inventor); Lowe, David M. (Inventor)

    1994-01-01

    An improved composite flexible blanket insulation is presented comprising top silicon carbide having an interlock design, wherein the reflective shield is composed of single or double aluminized polyimide and wherein the polyimide film has a honeycomb pattern.

  1. Flexible memory networks.

    PubMed

    Curto, Carina; Degeratu, Anda; Itskov, Vladimir

    2012-03-01

    Networks of neurons in some brain areas are flexible enough to encode new memories quickly. Using a standard firing rate model of recurrent networks, we develop a theory of flexible memory networks. Our main results characterize networks having the maximal number of flexible memory patterns, given a constraint graph on the network's connectivity matrix. Modulo a mild topological condition, we find a close connection between maximally flexible networks and rank 1 matrices. The topological condition is H (1)(X;ℤ)=0, where X is the clique complex associated to the network's constraint graph; this condition is generically satisfied for large random networks that are not overly sparse. In order to prove our main results, we develop some matrix-theoretic tools and present them in a self-contained section independent of the neuroscience context. PMID:21826564

  2. Flexible Polyhedral Surfaces.

    ERIC Educational Resources Information Center

    Alexandrov, V. A.

    1998-01-01

    Discusses some questions connected with Cauchy's theorem which states that two convex closed polyhedral surfaces whose corresponding faces are congruent and whose faces adjoin each other in the same way are congruent. Describes how to construct a flexible polyhedron. (ASK)

  3. Flexibility in insulin prescription.

    PubMed

    Kalra, Sanjay; Gupta, Yashdeep; Unnikrishnan, Ambika Gopalakrishnan

    2016-01-01

    This communication explores the concept of flexibility, a propos insulin preparations and insulin regimes used in the management of type 2 diabetes. The flexibility of an insulin regime or preparation is defined as their ability to be injected at variable times, with variable injection-meal time gaps, in a dose frequency and quantum determined by shared decision making, with a minimal requirement of glucose monitoring and health professional consultation, with no compromise on safety, efficiency and tolerability. The relative flexibility of various basal, prandial and dual action insulins, as well as intensive regimes, is compared. The biopsychosocial model of health is used to assess the utility of different insulins while encouraging a philosophy of flexible insulin usage. PMID:27186563

  4. Flexible sliding seal

    NASA Technical Reports Server (NTRS)

    Wallenhorst, E. L.

    1980-01-01

    Circular seal both slides and flexes to accomodate relative motion between two sealed members. Originally developed for Space Shuttle orbiter, it contains sliding seal to accommodate engine gimbaling and flexible seal that absorbs forward motion at high thrust of engine heat shield relative to airframe. Other possible applications are in support structures of heavy machinery and vehicle engines. Flexible sliding seal is ring about 7 feet in diameter and can withstand temperatures up to 1,600 F.

  5. Flexible production systems

    NASA Astrophysics Data System (ADS)

    Chudakov, A. D.; Shchetinin, D. D.

    1986-03-01

    Flexible production systems are a technological tool design to automate multiple product line manufacturing. Flexible production systems provide an efficient means of organizing combined equipment operations and bring the production organization nearer to an unmanned arrangement or one requiring a limited number of workers. This is achieved by intensifying and automating manufacturing processes; coordinating the automated processes involved in warehousing and materials transport to maintain a tight production path; and using computers to automate production preparation and production control. The prerequisites for a change to these new production structures include numerical control NC tools and machining centers, power connection points for robots, automated conveying and warehousing systems controlled by microelectronic devices and control computer complexes consisting primarily of microprocessor-based units capable of controlling equipment via a direct connection and on a real-time basis. The types of flexible production systems in operation are divided into three groups: (1) flexible automated lines (GAL), (2) flexible production modules (GPM); and (3) flexible production complexes (GPK).

  6. Method of sealing an ultracapacitor substantially free of water

    DOEpatents

    Chapman-Irwin, Patricia; Feist, Thomas Paul

    2002-04-02

    A method of sealing an ultracapacitor substantially free of water is disclosed. The method includes providing a multilayer cell comprising two solid, non porous current collectors, separated by two porous electrodes with a separator between the two electrodes, sealing the cell with a reclosable hermetic closure. Water inside the closure is dissociated by an applied voltage to the cell and escapes in the form of hydrogen and oxygen when the closure is unmated, the closure is then mated to hermetically seal the cell which is substantially free of water.

  7. 76 FR 38961 - Tobacco Products, Exemptions From Substantial Equivalence Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-05

    ... / Tuesday, July 5, 2011 / Rules and Regulations#0;#0; ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and... Substantial Equivalence Requirements AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is issuing this final rule to establish procedures...

  8. 29 CFR 4043.27 - Distribution to a substantial owner.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... TERMINATIONS REPORTABLE EVENTS AND CERTAIN OTHER NOTIFICATION REQUIREMENTS Post-Event Notice of Reportable Events § 4043.27 Distribution to a substantial owner. (a) Reportable event. A reportable event occurs for... does not exceed the limitation (as of the date the reportable event occurs) under section...

  9. 29 CFR 4043.27 - Distribution to a substantial owner.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Distribution to a substantial owner. 4043.27 Section 4043.27 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION PLAN TERMINATIONS REPORTABLE EVENTS AND CERTAIN OTHER NOTIFICATION REQUIREMENTS Post-Event Notice of Reportable Events § 4043.27 Distribution to a...

  10. 29 CFR 4043.27 - Distribution to a substantial owner.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... TERMINATIONS REPORTABLE EVENTS AND CERTAIN OTHER NOTIFICATION REQUIREMENTS Post-Event Notice of Reportable Events § 4043.27 Distribution to a substantial owner. (a) Reportable event. A reportable event occurs for... does not exceed the limitation (as of the date the reportable event occurs) under section...

  11. 29 CFR 4043.27 - Distribution to a substantial owner.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Distribution to a substantial owner. 4043.27 Section 4043.27 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION PLAN TERMINATIONS REPORTABLE EVENTS AND CERTAIN OTHER NOTIFICATION REQUIREMENTS Post-Event Notice of Reportable Events § 4043.27 Distribution to a...

  12. 29 CFR 4043.27 - Distribution to a substantial owner.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... TERMINATIONS REPORTABLE EVENTS AND CERTAIN OTHER NOTIFICATION REQUIREMENTS Post-Event Notice of Reportable Events § 4043.27 Distribution to a substantial owner. (a) Reportable event. A reportable event occurs for... does not exceed the limitation (as of the date the reportable event occurs) under section...

  13. 77 FR 35245 - Substantially Underserved Trust Areas (SUTA)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    ... entitled ``Department Programs and Activities Excluded from Executive Order 12372,'' (50 FR 47034). However... October 14, 2011, (76 FR 63846), the agency requested comments regarding implementing the Substantially... Guarantees. The Catalog is available on the Internet at http://www.cfda.gov . Executive Order 12372...

  14. 20 CFR 404.1510 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Meaning of substantial gainful activity. 404.1510 Section 404.1510 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Definition of Disability §...

  15. 20 CFR 404.1510 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Meaning of substantial gainful activity. 404.1510 Section 404.1510 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Definition of Disability §...

  16. 20 CFR 404.1510 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Meaning of substantial gainful activity. 404.1510 Section 404.1510 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Definition of Disability §...

  17. 20 CFR 404.1510 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Meaning of substantial gainful activity. 404.1510 Section 404.1510 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Definition of Disability §...

  18. 20 CFR 404.1510 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Meaning of substantial gainful activity. 404.1510 Section 404.1510 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Definition of Disability §...

  19. 15 CFR 970.209 - Substantial compliance with application requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 3 2014-01-01 2014-01-01 false Substantial compliance with application requirements. 970.209 Section 970.209 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL...

  20. 76 FR 737 - Tobacco Products, Exemptions From Substantial Equivalence Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-06

    ...The Food and Drug Administration (FDA) is issuing this proposed rule to establish procedures for requesting an exemption from the substantial equivalence requirements of the Family Smoking Prevention and Tobacco Control Act (Tobacco Control Act). The proposed rule would describe the process and statutory criteria for requesting an exemption and explain how FDA would review requests for......

  1. 15 CFR 970.209 - Substantial compliance with application requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Substantial compliance with application requirements. 970.209 Section 970.209 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL...

  2. 15 CFR 970.209 - Substantial compliance with application requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Substantial compliance with application requirements. 970.209 Section 970.209 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL...

  3. 26 CFR 7.105-2 - Substantial gainful activity.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 14 2012-04-01 2012-04-01 false Substantial gainful activity. 7.105-2 Section 7.105-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX... because of a physical or mental impairment accepts sheltered employment in a protected environment...

  4. 26 CFR 7.105-2 - Substantial gainful activity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Substantial gainful activity. 7.105-2 Section 7.105-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX... because of a physical or mental impairment accepts sheltered employment in a protected environment...

  5. Mistreatment in Assisted Living Facilities: Complaints, Substantiations, and Risk Factors

    ERIC Educational Resources Information Center

    Phillips, Linda R.; Guo, Guifang

    2011-01-01

    Purpose of the Study: Use archived public data from Arizona to explore relationships among selected institutional and resident risk and situation-specific factors and complaints and substantiated allegations of various types of mistreatment in assisted living facilities (ALFs). Design and Methods: An exploratory/descriptive 2-group design was…

  6. 29 CFR 4.12 - Substantial interest proceedings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... procedures set forth at 29 CFR part 6. (f) Referral to the Administrative Review Board. When the person or... accordance with the procedures set forth at 29 CFR part 8. ... 29 Labor 1 2010-07-01 2010-07-01 true Substantial interest proceedings. 4.12 Section 4.12...

  7. 20 CFR 416.910 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Meaning of substantial gainful activity. 416.910 Section 416.910 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Definition of Disability §...

  8. 20 CFR 416.910 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Meaning of substantial gainful activity. 416.910 Section 416.910 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Definition of Disability §...

  9. 20 CFR 416.910 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Meaning of substantial gainful activity. 416.910 Section 416.910 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Definition of Disability §...

  10. 20 CFR 416.910 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Meaning of substantial gainful activity. 416.910 Section 416.910 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Definition of Disability §...

  11. 20 CFR 416.910 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Meaning of substantial gainful activity. 416.910 Section 416.910 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Definition of Disability §...

  12. 15 CFR 970.209 - Substantial compliance with application requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Substantial compliance with application requirements. 970.209 Section 970.209 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL...

  13. Optimization of the double dosimetry algorithm for interventional cardiologists

    NASA Astrophysics Data System (ADS)

    Chumak, Vadim; Morgun, Artem; Bakhanova, Elena; Voloskiy, Vitalii; Borodynchik, Elena

    2014-11-01

    A double dosimetry method is recommended in interventional cardiology (IC) to assess occupational exposure; yet currently there is no common and universal algorithm for effective dose estimation. In this work, flexible and adaptive algorithm building methodology was developed and some specific algorithm applicable for typical irradiation conditions of IC procedures was obtained. It was shown that the obtained algorithm agrees well with experimental measurements and is less conservative compared to other known algorithms.

  14. Flexible Residential Smart Grid Simulation Framework

    NASA Astrophysics Data System (ADS)

    Xiang, Wang

    Different scheduling and coordination algorithms controlling household appliances' operations can potentially lead to energy consumption reduction and/or load balancing in conjunction with different electricity pricing methods used in smart grid programs. In order to easily implement different algorithms and evaluate their efficiency against other ideas, a flexible simulation framework is desirable in both research and business fields. However, such a platform is currently lacking or underdeveloped. In this thesis, we provide a simulation framework to focus on demand side residential energy consumption coordination in response to different pricing methods. This simulation framework, equipped with an appliance consumption library using realistic values, aims to closely represent the average usage of different types of appliances. The simulation results of traditional usage yield close matching values compared to surveyed real life consumption records. Several sample coordination algorithms, pricing schemes, and communication scenarios are also implemented to illustrate the use of the simulation framework.

  15. Numerical simulation of mechanisms and manipulator robots with flexible links and flexible joints

    NASA Astrophysics Data System (ADS)

    Gong, D.

    1995-01-01

    This thesis deals with numerical simulation of mechanical systems like mechanisms and manipulator robots. The mechanical system may be considered in a two or three dimensional space, may have electrical machines, and may contain flexible links and flexible joints. Methods and algorithms to perform static analysis, kinematic analysis, dynamic analysis, linearization of nonlinear systems, periodic solution of periodically forced systems and control simulation of robots have been applied. A finite element method is used to get the mathematical model for a mechanical system. Friendly interfaces for pre- and post-processing have been designed by using X Window on Sun workstations. An integrated program network and data base has been applied in the software system SPACAR. For the simulation of robots with flexible links and flexible joints, two linearization methods have been studied: the variational linearization method and the feedback linearization method. Numerical examples for simulation of robots with flexible links and flexible joints have been presented to show the elegance and powerfulness of the introduced methods and the designed software system.

  16. Flexible transparent electrode

    NASA Astrophysics Data System (ADS)

    Demiryont, Hulya; Shannon, Kenneth C., III; Moorehead, David; Bratcher, Matthew

    2011-06-01

    This paper presents the properties of the EclipseTECTM transparent conductor. EclipseTECTM is a room temperature deposited nanostructured thin film coating system comprised of metal-oxide semiconductor elements. The system possesses metal-like conductivity and glass-like transparency in the visible region. These highly conductive TEC films exhibit high shielding efficiency (35dB at 1 to 100GHz). EclipseTECTM can be deposited on rigid or flexible substrates. For example, EclipseTECTM deposited on polyethylene terephthalate (PET) is extremely flexible that can be rolled around a 9mm diameter cylinder with little or no reduction in electrical conductivity and that can assume pre-extension states after an applied stress is relieved. The TEC is colorless and has been tailored to have high visible transmittance which matches the eye sensitivity curve and allows the viewing of true background colors through the coating. EclipseTECTM is flexible, durable and can be tailored at the interface for applications such as electron- or hole-injecting OLED electrodes as well as electrodes in flexible displays. Tunable work function and optical design flexibility also make EclipseTECTM well-suited as a candidate for grid electrode replacement in next-generation photovoltaic cells.

  17. Printed Microinductors for Flexible Substrates

    NASA Technical Reports Server (NTRS)

    Brandon, Erik; Whitacre, Jay; Wesseling, Emily

    2005-01-01

    A method of fabricating planar, flexible microinductors that exhibit a relatively high quality factor (Q) between 1 and 10 MHz has been devised. These inductors are targeted for use in flexible, low-profile power-converter circuits. They could also be incorporated into electronic circuits integrated into flexible structures, including flexible antenna and solar-sail structures that are deployable.

  18. Applying Side-chain Flexibility in Motifs for Protein Docking

    PubMed Central

    Liu, Hui; Lin, Feng; Yang, Jian-Li; Wang, Hong-Rui; Liu, Xiu-Ling

    2015-01-01

    Conventional rigid docking algorithms have been unsatisfactory in their computational results, largely due to the fact that protein structures are flexible in live environments. In response, we propose to introduce the side-chain flexibility in protein motif into the docking. First, the Morse theory is applied to curvature labeling and surface region growing, for segmentation of the protein surface into smaller patches. Then, the protein is described by an ensemble of conformations that incorporate the flexibility of interface side chains and are sampled using rotamers. Next, a 3D rotation invariant shape descriptor is proposed to deal with the flexible motifs and surface patches; thus, pairwise complementarity matching is needed only between the convex patches of ligand and the concave patches of receptor. The iterative closest point (ICP) algorithm is implemented for geometric alignment of the two 3D protein surface patches. Compared with the fast Fourier transform-based global geometric matching algorithm and other methods, our FlexDock system generates much less false-positive docking results, which benefits identification of the complementary candidates. Our computational experiments show the advantages of the proposed flexible docking algorithm over its counterparts. PMID:26508871

  19. Applying Side-chain Flexibility in Motifs for Protein Docking.

    PubMed

    Liu, Hui; Lin, Feng; Yang, Jian-Li; Wang, Hong-Rui; Liu, Xiu-Ling

    2015-01-01

    Conventional rigid docking algorithms have been unsatisfactory in their computational results, largely due to the fact that protein structures are flexible in live environments. In response, we propose to introduce the side-chain flexibility in protein motif into the docking. First, the Morse theory is applied to curvature labeling and surface region growing, for segmentation of the protein surface into smaller patches. Then, the protein is described by an ensemble of conformations that incorporate the flexibility of interface side chains and are sampled using rotamers. Next, a 3D rotation invariant shape descriptor is proposed to deal with the flexible motifs and surface patches; thus, pairwise complementarity matching is needed only between the convex patches of ligand and the concave patches of receptor. The iterative closest point (ICP) algorithm is implemented for geometric alignment of the two 3D protein surface patches. Compared with the fast Fourier transform-based global geometric matching algorithm and other methods, our FlexDock system generates much less false-positive docking results, which benefits identification of the complementary candidates. Our computational experiments show the advantages of the proposed flexible docking algorithm over its counterparts. PMID:26508871

  20. Protein folding in hydrophobic-polar lattice model: a flexible ant-colony optimization approach.

    PubMed

    Hu, Xiao-Min; Zhang, Jun; Xiao, Jing; Li, Yun

    2008-01-01

    This paper proposes a flexible ant colony (FAC) algorithm for solving protein folding problems based on the hydrophobic-polar square lattice model. Collaborations of novel pheromone and heuristic strategies in the proposed algorithm make it more effective in predicting structures of proteins compared with other state-of-the-art algorithms. PMID:18537736

  1. Improved Thin, Flexible Heat Pipes

    NASA Technical Reports Server (NTRS)

    Rosenfeld, John H.; Gernert, Nelson J.; Sarraf, David B.; Wollen, Peter J.; Surina, Frank C.; Fale, John E.

    2004-01-01

    Flexible heat pipes of an improved type are fabricated as layers of different materials laminated together into vacuum- tight sheets or tapes. In comparison with prior flexible heat pipes, these flexible heat pipes are less susceptible to leakage. Other advantages of these flexible heat pipes, relative to prior flexible heat pipes, include high reliability and greater ease and lower cost of fabrication. Because these heat pipes are very thin, they are highly flexible. When coated on outside surfaces with adhesives, these flexible heat pipes can be applied, like common adhesive tapes, to the surfaces of heat sinks and objects to be cooled, even if those surfaces are curved.

  2. Natural flexible dermal armor.

    PubMed

    Yang, Wen; Chen, Irene H; Gludovatz, Bernd; Zimmermann, Elizabeth A; Ritchie, Robert O; Meyers, Marc A

    2013-01-01

    Fish, reptiles, and mammals can possess flexible dermal armor for protection. Here we seek to find the means by which Nature derives its protection by examining the scales from several fish (Atractosteus spatula, Arapaima gigas, Polypterus senegalus, Morone saxatilis, Cyprinius carpio), and osteoderms from armadillos, alligators, and leatherback turtles. Dermal armor has clearly been developed by convergent evolution in these different species. In general, it has a hierarchical structure with collagen fibers joining more rigid units (scales or osteoderms), thereby increasing flexibility without significantly sacrificing strength, in contrast to rigid monolithic mineral composites. These dermal structures are also multifunctional, with hydrodynamic drag (in fish), coloration for camouflage or intraspecies recognition, temperature and fluid regulation being other important functions. The understanding of such flexible dermal armor is important as it may provide a basis for new synthetic, yet bioinspired, armor materials. PMID:23161399

  3. Spatial operator approach to flexible multibody system dynamics and control

    NASA Technical Reports Server (NTRS)

    Rodriguez, G.

    1991-01-01

    The inverse and forward dynamics problems for flexible multibody systems were solved using the techniques of spatially recursive Kalman filtering and smoothing. These algorithms are easily developed using a set of identities associated with mass matrix factorization and inversion. These identities are easily derived using the spatial operator algebra developed by the author. Current work is aimed at computational experiments with the described algorithms and at modelling for control design of limber manipulator systems. It is also aimed at handling and manipulation of flexible objects.

  4. Substantial Life Extension and the Fair Distribution of Healthspans.

    PubMed

    Wareham, Christopher S

    2016-10-01

    One of the strongest objections to the development and use of substantially life-extending interventions is that they would exacerbate existing unjust disparities of healthy lifespans between rich and poor members of society. In both popular opinion and ethical theory, this consequence is sometimes thought to justify a ban on life-prolonging technologies. However, the practical and ethical drawbacks of banning receive little attention, and the viability of alternative policies is seldom considered. Moreover, where ethicists do propose alternatives, there is scant effort to consider their merits in light of developing world priorities. In response to these shortcomings, I distinguish four policy options and, on the basis of a plausible intuition about fairness, evaluate their implications for a fair distribution of healthy lifespans. I claim that even in developing nations it would be fairest to favor policies that promote equal access to at least one promising category of substantially life-extending intervention: calorie restriction mimetics. PMID:27465775

  5. Patients' substantialization of disease, the hybrid symptom and metaphysical care.

    PubMed

    Pârvan, Alexandra

    2015-06-01

    In the context of current scholarship concerned with facilitating integration between the biomedical and the patient-centred models of care, the article suggests that disease brings about an ontological disruption in patients, which is not directly addressed in either model, and may interfere with treatment and therapy outcomes if not met with a type of care termed here as 'metaphysical'. The receipt of diagnosis and medical care can give patients the sense that they are ontologically diminished, or less of a human, and along with physicians' approaches to and discourses about disease, may prompt them to seek ontological restoration or security in the same way as psychologically traumatized patients sometimes do: by treating the disease and/or the experience of harm associated with it as a thing that exists per se. I call this 'substantialization' of disease (or harm) and draw on Augustine's theory of non-substantial deficiencies (physiological and moral) and on Plato's and Plotinus's different takes on such defects in order to discuss what substantialization can do for patients. Based on literature that examines patients' ways of talking about and living with their disease, I speculate that substantialization can generate a 'hybrid symptom', consisting in patterns of exercising agency which may predispose to non-adherence. Ways in which physicians could provide metaphysical care are proposed, along with an understanding of chronic patients as hybrid ontological and agentic units, which draws on theories of enactive cognition. I opine that metaphysical care may facilitate integration between the depersonalized and personalized models of care. PMID:25312387

  6. Automatic Filtering and Substantiation of Drug Safety Signals

    PubMed Central

    Bauer-Mehren, Anna; van Mullingen, Erik M.; Avillach, Paul; Carrascosa, María del Carmen; Garcia-Serna, Ricard; Piñero, Janet; Singh, Bharat; Lopes, Pedro; Oliveira, José L.; Diallo, Gayo; Ahlberg Helgee, Ernst; Boyer, Scott; Mestres, Jordi; Sanz, Ferran; Kors, Jan A.; Furlong, Laura I.

    2012-01-01

    Drug safety issues pose serious health threats to the population and constitute a major cause of mortality worldwide. Due to the prominent implications to both public health and the pharmaceutical industry, it is of great importance to unravel the molecular mechanisms by which an adverse drug reaction can be potentially elicited. These mechanisms can be investigated by placing the pharmaco-epidemiologically detected adverse drug reaction in an information-rich context and by exploiting all currently available biomedical knowledge to substantiate it. We present a computational framework for the biological annotation of potential adverse drug reactions. First, the proposed framework investigates previous evidences on the drug-event association in the context of biomedical literature (signal filtering). Then, it seeks to provide a biological explanation (signal substantiation) by exploring mechanistic connections that might explain why a drug produces a specific adverse reaction. The mechanistic connections include the activity of the drug, related compounds and drug metabolites on protein targets, the association of protein targets to clinical events, and the annotation of proteins (both protein targets and proteins associated with clinical events) to biological pathways. Hence, the workflows for signal filtering and substantiation integrate modules for literature and database mining, in silico drug-target profiling, and analyses based on gene-disease networks and biological pathways. Application examples of these workflows carried out on selected cases of drug safety signals are discussed. The methodology and workflows presented offer a novel approach to explore the molecular mechanisms underlying adverse drug reactions. PMID:22496632

  7. Flexible radiator system

    NASA Technical Reports Server (NTRS)

    Oren, J. A.

    1982-01-01

    The soft tube radiator subsystem is described including applicable system requirements, the design and limitations of the subsystem components, and the panel manufacturing method. The soft tube radiator subsystem is applicable to payloads requiring 1 to 12 kW of heat rejection for orbital lifetimes per mission of 30 days or less. The flexible radiator stowage volume required is about 60% and the system weight is about 40% of an equivalent heat rejection rigid panel. The cost should also be considerably less. The flexible radiator is particularly suited to shuttle orbiter sortie payloads and also whose mission lengths do not exceed the 30 day design life.

  8. Thin flexible intercalation anodes

    SciTech Connect

    Levy, S.C.; Cieslak, W.R.; Klassen, S.E.; Lagasse, R.R.

    1994-10-01

    Poly(acrylonitrile) fibers have been pyrolyzed under various conditions to form flexible carbon yarns capable of intercalating lithium ions. These fibers have also been formed into both woven and non woven cloths. Potentiostatic, potentiodynamic and galvanostatic tests have been conducted with these materials in several electrolytes. In some tests, a potential hold was used after each constant current charge and discharge. These tests have shown some of these flexible materials to reversibly intercalate lithium ions to levels that are suitable for use as a practical battery anode.

  9. Scanning of wind turbine upwind conditions: numerical algorithm and first applications

    NASA Astrophysics Data System (ADS)

    Calaf, Marc; Cortina, Gerard; Sharma, Varun; Parlange, Marc B.

    2014-11-01

    Wind turbines still obtain in-situ meteorological information by means of traditional wind vane and cup anemometers installed at the turbine's nacelle, right behind the blades. This has two important drawbacks: 1-turbine misalignment with the mean wind direction is common and energy losses are experienced; 2-the near-blade monitoring does not provide any time to readjust the profile of the wind turbine to incoming turbulence gusts. A solution is to install wind Lidar devices on the turbine's nacelle. This technique is currently under development as an alternative to traditional in-situ wind anemometry because it can measure the wind vector at substantial distances upwind. However, at what upwind distance should they interrogate the atmosphere? A new flexible wind turbine algorithm for large eddy simulations of wind farms that allows answering this question, will be presented. The new wind turbine algorithm timely corrects the turbines' yaw misalignment with the changing wind. The upwind scanning flexibility of the algorithm also allows to track the wind vector and turbulent kinetic energy as they approach the wind turbine's rotor blades. Results will illustrate the spatiotemporal evolution of the wind vector and the turbulent kinetic energy as the incoming flow approaches the wind turbine under different atmospheric stability conditions. Results will also show that the available atmospheric wind power is larger during daytime periods at the cost of an increased variance.

  10. Fast and anisotropic flexibility-rigidity index for protein flexibility and fluctuation analysis

    SciTech Connect

    Opron, Kristopher; Xia, Kelin; Wei, Guo-Wei

    2014-06-21

    Protein structural fluctuation, typically measured by Debye-Waller factors, or B-factors, is a manifestation of protein flexibility, which strongly correlates to protein function. The flexibility-rigidity index (FRI) is a newly proposed method for the construction of atomic rigidity functions required in the theory of continuum elasticity with atomic rigidity, which is a new multiscale formalism for describing excessively large biomolecular systems. The FRI method analyzes protein rigidity and flexibility and is capable of predicting protein B-factors without resorting to matrix diagonalization. A fundamental assumption used in the FRI is that protein structures are uniquely determined by various internal and external interactions, while the protein functions, such as stability and flexibility, are solely determined by the structure. As such, one can predict protein flexibility without resorting to the protein interaction Hamiltonian. Consequently, bypassing the matrix diagonalization, the original FRI has a computational complexity of O(N{sup 2}). This work introduces a fast FRI (fFRI) algorithm for the flexibility analysis of large macromolecules. The proposed fFRI further reduces the computational complexity to O(N). Additionally, we propose anisotropic FRI (aFRI) algorithms for the analysis of protein collective dynamics. The aFRI algorithms permit adaptive Hessian matrices, from a completely global 3N × 3N matrix to completely local 3 × 3 matrices. These 3 × 3 matrices, despite being calculated locally, also contain non-local correlation information. Eigenvectors obtained from the proposed aFRI algorithms are able to demonstrate collective motions. Moreover, we investigate the performance of FRI by employing four families of radial basis correlation functions. Both parameter optimized and parameter-free FRI methods are explored. Furthermore, we compare the accuracy and efficiency of FRI with some established approaches to flexibility analysis, namely

  11. Fast and anisotropic flexibility-rigidity index for protein flexibility and fluctuation analysis

    NASA Astrophysics Data System (ADS)

    Opron, Kristopher; Xia, Kelin; Wei, Guo-Wei

    2014-06-01

    Protein structural fluctuation, typically measured by Debye-Waller factors, or B-factors, is a manifestation of protein flexibility, which strongly correlates to protein function. The flexibility-rigidity index (FRI) is a newly proposed method for the construction of atomic rigidity functions required in the theory of continuum elasticity with atomic rigidity, which is a new multiscale formalism for describing excessively large biomolecular systems. The FRI method analyzes protein rigidity and flexibility and is capable of predicting protein B-factors without resorting to matrix diagonalization. A fundamental assumption used in the FRI is that protein structures are uniquely determined by various internal and external interactions, while the protein functions, such as stability and flexibility, are solely determined by the structure. As such, one can predict protein flexibility without resorting to the protein interaction Hamiltonian. Consequently, bypassing the matrix diagonalization, the original FRI has a computational complexity of O(N^2). This work introduces a fast FRI (fFRI) algorithm for the flexibility analysis of large macromolecules. The proposed fFRI further reduces the computational complexity to O(N). Additionally, we propose anisotropic FRI (aFRI) algorithms for the analysis of protein collective dynamics. The aFRI algorithms permit adaptive Hessian matrices, from a completely global 3N × 3N matrix to completely local 3 × 3 matrices. These 3 × 3 matrices, despite being calculated locally, also contain non-local correlation information. Eigenvectors obtained from the proposed aFRI algorithms are able to demonstrate collective motions. Moreover, we investigate the performance of FRI by employing four families of radial basis correlation functions. Both parameter optimized and parameter-free FRI methods are explored. Furthermore, we compare the accuracy and efficiency of FRI with some established approaches to flexibility analysis, namely, normal

  12. Frequency response modeling and control of flexible structures: Computational methods

    NASA Technical Reports Server (NTRS)

    Bennett, William H.

    1989-01-01

    The dynamics of vibrations in flexible structures can be conventiently modeled in terms of frequency response models. For structural control such models capture the distributed parameter dynamics of the elastic structural response as an irrational transfer function. For most flexible structures arising in aerospace applications the irrational transfer functions which arise are of a special class of pseudo-meromorphic functions which have only a finite number of right half place poles. Computational algorithms are demonstrated for design of multiloop control laws for such models based on optimal Wiener-Hopf control of the frequency responses. The algorithms employ a sampled-data representation of irrational transfer functions which is particularly attractive for numerical computation. One key algorithm for the solution of the optimal control problem is the spectral factorization of an irrational transfer function. The basis for the spectral factorization algorithm is highlighted together with associated computational issues arising in optimal regulator design. Options for implementation of wide band vibration control for flexible structures based on the sampled-data frequency response models is also highlighted. A simple flexible structure control example is considered to demonstrate the combined frequency response modeling and control algorithms.

  13. Launch flexibility using NLP guidance and remote wind sensing

    NASA Technical Reports Server (NTRS)

    Cramer, Evin J.; Bradt, Jerre E.; Hardtla, John W.

    1990-01-01

    This paper examines the use of lidar wind measurements in the implementation of a guidance strategy for a nonlinear programming (NLP) launch guidance algorithm. The NLP algorithm uses B-spline command function representation for flexibility in the design of the guidance steering commands. Using this algorithm, the guidance system solves a two-point boundary value problem at each guidance update. The specification of different boundary value problems at each guidance update provides flexibility that can be used in the design of the guidance strategy. The algorithm can use lidar wind measurements for on pad guidance retargeting and for load limiting guidance steering commands. Examples presented in the paper use simulated wind updates to correct wind induced final orbit errors and to adjust the guidance steering commands to limit the product of the dynamic pressure and angle-of-attack for launch vehicle load alleviation.

  14. Flexible Classroom Furniture

    ERIC Educational Resources Information Center

    Kim Hassell,

    2011-01-01

    Classroom design for the 21st-century learning environment should accommodate a variety of learning skills and needs. The space should be large enough so it can be configured to accommodate a number of learning activities. This also includes furniture that provides flexibility and accommodates collaboration and interactive work among students and…

  15. Designing Flexible Instruction

    ERIC Educational Resources Information Center

    Harris, Clark R.; Kaff, Marilyn S.; Anderson, Mary Jo; Knackendoffel, Ann

    2007-01-01

    Principals and teachers need a framework that will allow school personnel to reach and teach all students within the general education setting. One such framework is universal design for learning (UDL). UDL is achieved by means of flexible curricular materials and activities that provide alternatives for students with disparities in abilities and…

  16. Flexible electronics: Sophisticated skin

    NASA Astrophysics Data System (ADS)

    Bauer, Siegfried

    2013-10-01

    Advances in materials science and layout design have enabled the realization of flexible and multifunctional electronic devices. Two demonstrations of electronic skins, which combine temperature and pressure sensing with integrated thermal actuators and organic displays, unveil the potential of these devices for robotics and clinical applications.

  17. Diversity and Flexibility.

    ERIC Educational Resources Information Center

    Anastasi, Anne

    1990-01-01

    Responds to five major articles by Duckworth, Goldman, Healy, Sampson, and Goodyear on issues pertaining to testing and assessment in counseling psychology. Suggests that such a diversity of approaches leads to a more comprehensive and flexible model of counseling, adaptable to differences in clients, context, and counselor personalities. (TE)

  18. Flexible photovoltaic device

    SciTech Connect

    Berman, E.

    1989-03-28

    A photovoltaic device is described comprising a transparent substrate, a transparent conductive layer adjacent to the transparent substrate, a TFS layer adjacent to the transparent conductive layer, and a conductive layer adjacent to the TFS layer, the transparent substrate being a tetrafluoroethyleneperfluoroalkooxy resin in the form of a flexible film.

  19. Flexible optical panel

    DOEpatents

    Veligdan, James T.

    2001-01-01

    A flexible optical panel includes laminated optical waveguides, each including a ribbon core laminated between cladding, with the core being resilient in the plane of the core for elastically accommodating differential movement thereof to permit winding of the panel in a coil.

  20. ESEA Flexibility. Updated

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    In order to move forward with State and local reforms designed to improve academic achievement and increase the quality of instruction for all students in a manner that was not originally contemplated by the No Child Left Behind Act of 2001 (NCLB), a State educational agency (SEA) may request flexibility, on its own behalf and on behalf of its…

  1. Quantum algorithms

    NASA Astrophysics Data System (ADS)

    Abrams, Daniel S.

    This thesis describes several new quantum algorithms. These include a polynomial time algorithm that uses a quantum fast Fourier transform to find eigenvalues and eigenvectors of a Hamiltonian operator, and that can be applied in cases (commonly found in ab initio physics and chemistry problems) for which all known classical algorithms require exponential time. Fast algorithms for simulating many body Fermi systems are also provided in both first and second quantized descriptions. An efficient quantum algorithm for anti-symmetrization is given as well as a detailed discussion of a simulation of the Hubbard model. In addition, quantum algorithms that calculate numerical integrals and various characteristics of stochastic processes are described. Two techniques are given, both of which obtain an exponential speed increase in comparison to the fastest known classical deterministic algorithms and a quadratic speed increase in comparison to classical Monte Carlo (probabilistic) methods. I derive a simpler and slightly faster version of Grover's mean algorithm, show how to apply quantum counting to the problem, develop some variations of these algorithms, and show how both (apparently distinct) approaches can be understood from the same unified framework. Finally, the relationship between physics and computation is explored in some more depth, and it is shown that computational complexity theory depends very sensitively on physical laws. In particular, it is shown that nonlinear quantum mechanics allows for the polynomial time solution of NP-complete and #P oracle problems. Using the Weinberg model as a simple example, the explicit construction of the necessary gates is derived from the underlying physics. Nonlinear quantum algorithms are also presented using Polchinski type nonlinearities which do not allow for superluminal communication. (Copies available exclusively from MIT Libraries, Rm. 14- 0551, Cambridge, MA 02139-4307. Ph. 617-253-5668; Fax 617-253-1690.)

  2. Scheduling Jobs with Genetic Algorithms

    NASA Astrophysics Data System (ADS)

    Ferrolho, António; Crisóstomo, Manuel

    Most scheduling problems are NP-hard, the time required to solve the problem optimally increases exponentially with the size of the problem. Scheduling problems have important applications, and a number of heuristic algorithms have been proposed to determine relatively good solutions in polynomial time. Recently, genetic algorithms (GA) are successfully used to solve scheduling problems, as shown by the growing numbers of papers. GA are known as one of the most efficient algorithms for solving scheduling problems. But, when a GA is applied to scheduling problems various crossovers and mutations operators can be applicable. This paper presents and examines a new concept of genetic operators for scheduling problems. A software tool called hybrid and flexible genetic algorithm (HybFlexGA) was developed to examine the performance of various crossover and mutation operators by computing simulations of job scheduling problems.

  3. Creating Connections: College Innovations in Flexibility, Access and Participation.

    ERIC Educational Resources Information Center

    Further Education Development Agency, London (England).

    This document contains 14 papers explaining how 12 further education colleges in the United Kingdom used fellowship funds to maximize their use of current information and learning technologies and make other substantial innovations to improve their flexibility, accessibility, and rates of participation. The following papers are included: "Leading…

  4. Thin film with oriented cracks on a flexible substrate

    DOEpatents

    Feng, Bao; McGilvray, Andrew; Shi, Bo

    2010-07-27

    A thermoelectric film is disclosed. The thermoelectric film includes a substrate that is substantially electrically non-conductive and flexible and a thermoelectric material that is deposited on at least one surface of the substrate. The thermoelectric film also includes multiple cracks oriented in a predetermined direction.

  5. Flexible Docking of Proteins and "Drug-like" Ligands.

    PubMed

    Tang, Hai-Xu; Ye, Yu-Zhen; Ding, Da-Fu

    1998-01-01

    By using "tabu search" algorithm and Gehlhaar potential function, a new approach is presented for flexible docking of protein and its "drug-like" ligand has been developed. Computational test for this method with a set of 100 complexes has been performed, which indicated that the deviation of 89% of the predicted complex conformation was less than 0.25 nm. Compared with GOLD, a program of genetic algorithm, our method has high accuracy, low limit and short computation time. PMID:12168000

  6. CZT vs FFT: Flexibility vs Speed

    SciTech Connect

    S. Sirin

    2003-10-01

    Bluestein's Fast Fourier Transform (FFT), commonly called the Chirp-Z Transform (CZT), is a little-known algorithm that offers engineers a high-resolution FFT combined with the ability to specify bandwidth. In the field of digital signal processing, engineers are always challenged to detect tones, frequencies, signatures, or some telltale sign that signifies a condition that must be indicated, ignored, or controlled. One of these challenges is to detect specific frequencies, for instance when looking for tones from telephones or detecting 60-Hz noise on power lines. The Goertzel algorithm described in Embedded Systems Programming, September 2002, offered a powerful tool toward finding specific frequencies faster than the FFT.Another challenge involves analyzing a range of frequencies, such as recording frequency response measurements, matching voice patterns, or displaying spectrum information on the face of an amateur radio. To meet this challenge most engineers use the well-known FFT. The CZT gives the engineer the flexibility to specify bandwidth and outputs real and imaginary frequency components from which the magnitude and phase can be computed. A description of the CZT and a discussion of the advantages and disadvantages of CZT versus the FFT and Goertzel algorithms will be followed by situations in which the CZT would shine. The reader will find that the CZT is very useful but that flexibility has a price.

  7. A flexible sequential Gaussian simulation program: USGSIM

    NASA Astrophysics Data System (ADS)

    Manchuk, John G.; Deutsch, Clayton V.

    2012-04-01

    Sequential Gaussian simulation is a widely used algorithm for the stochastic characterization of properties from various earth science disciplines. Many variants have been developed to deal with the increasing complexity of modeling applications. The program described in this paper is a flexible, tested, and documented implementation. Multiple variables can be cosimulated within different rock types simultaneously. The stepwise transform is integrated into the program as are collocated cokriging, collocated cokriging with the intrinsic model, and cokriging with a linear model of coregionalization for the cosimulation of multiple variables. Multiple secondary data can be incorporated using locally varying means, collocated cokriging, and Bayesian updating. The search options and other parameters are flexible within rock types. Fortran source code and a compiled executable are provided.

  8. Haplotyping algorithms

    SciTech Connect

    Sobel, E.; Lange, K.; O`Connell, J.R.

    1996-12-31

    Haplotyping is the logical process of inferring gene flow in a pedigree based on phenotyping results at a small number of genetic loci. This paper formalizes the haplotyping problem and suggests four algorithms for haplotype reconstruction. These algorithms range from exhaustive enumeration of all haplotype vectors to combinatorial optimization by simulated annealing. Application of the algorithms to published genetic analyses shows that manual haplotyping is often erroneous. Haplotyping is employed in screening pedigrees for phenotyping errors and in positional cloning of disease genes from conserved haplotypes in population isolates. 26 refs., 6 figs., 3 tabs.

  9. FSD- FLEXIBLE SPACECRAFT DYNAMICS

    NASA Technical Reports Server (NTRS)

    Fedor, J. V.

    1994-01-01

    The Flexible Spacecraft Dynamics and Control program (FSD) was developed to aid in the simulation of a large class of flexible and rigid spacecraft. FSD is extremely versatile and can be used in attitude dynamics and control analysis as well as in-orbit support of deployment and control of spacecraft. FSD has been used to analyze the in-orbit attitude performance and antenna deployment of the RAE and IMP class satellites, and the HAWKEYE, SCATHA, EXOS-B, and Dynamics Explorer flight programs. FSD is applicable to inertially-oriented spinning, earth oriented, or gravity gradient stabilized spacecraft. The spacecraft flexibility is treated in a continuous manner (instead of finite element) by employing a series of shape functions for the flexible elements. Torsion, bending, and three flexible modes can be simulated for every flexible element. FSD can handle up to ten tubular elements in an arbitrary orientation. FSD is appropriate for studies involving the active control of pointed instruments, with options for digital PID (proportional, integral, derivative) error feedback controllers and control actuators such as thrusters and momentum wheels. The input to FSD is in four parts: 1) Orbit Construction FSD calculates a Keplerian orbit with environmental effects such as drag, magnetic torque, solar pressure, thermal effects, and thruster adjustments; or the user can supply a GTDS format orbit tape for a particular satellite/time-span; 2) Control words - for options such as gravity gradient effects, control torques, and integration ranges; 3) Mathematical descriptions of spacecraft, appendages, and control systems- including element geometry, properties, attitudes, libration damping, tip mass inertia, thermal expansion, magnetic tracking, and gimbal simulation options; and 4) Desired state variables to output, i.e., geometries, bending moments, fast Fourier transform plots, gimbal rotation, filter vectors, etc. All FSD input is of free format, namelist construction. FSD

  10. Identifying Regions Based on Flexible User Defined Constraints.

    PubMed

    Folch, David C; Spielman, Seth E

    2014-01-01

    The identification of regions is both a computational and conceptual challenge. Even with growing computational power, regionalization algorithms must rely on heuristic approaches in order to find solutions. Therefore, the constraints and evaluation criteria that define a region must be translated into an algorithm that can efficiently and effectively navigate the solution space to find the best solution. One limitation of many existing regionalization algorithms is a requirement that the number of regions be selected a priori. The max-p algorithm, introduced in Duque et al. (2012), does not have this requirement, and thus the number of regions is an output of, not an input to, the algorithm. In this paper we extend the max-p algorithm to allow for greater flexibility in the constraints available to define a feasible region, placing the focus squarely on the multidimensional characteristics of region. We also modify technical aspects of the algorithm to provide greater flexibility in its ability to search the solution space. Using synthetic spatial and attribute data we are able to show the algorithm's broad ability to identify regions in maps of varying complexity. We also conduct a large scale computational experiment to identify parameter settings that result in the greatest solution accuracy under various scenarios. The rules of thumb identified from the experiment produce maps that correctly assign areas to their "true" region with 94% average accuracy, with nearly 50 percent of the simulations reaching 100 percent accuracy. PMID:25018663

  11. The Relegation Algorithm

    NASA Astrophysics Data System (ADS)

    Deprit, André; Palacián, Jesúus; Deprit, Etienne

    2001-03-01

    The relegation algorithm extends the method of normalization by Lie transformations. Given a Hamiltonian that is a power series ℋ = ℋ0+ ɛℋ1+ ... of a small parameter ɛ, normalization constructs a map which converts the principal part ℋ0into an integral of the transformed system — relegation does the same for an arbitrary function ℋ[G]. If the Lie derivative induced by ℋ[G] is semi-simple, a double recursion produces the generator of the relegating transformation. The relegation algorithm is illustrated with an elementary example borrowed from galactic dynamics; the exercise serves as a standard against which to test software implementations. Relegation is also applied to the more substantial example of a Keplerian system perturbed by radiation pressure emanating from a rotating source.

  12. Ascent guidance algorithm using lidar wind measurements

    NASA Technical Reports Server (NTRS)

    Cramer, Evin J.; Bradt, Jerre E.; Hardtla, John W.

    1990-01-01

    The formulation of a general nonlinear programming guidance algorithm that incorporates wind measurements in the computation of ascent guidance steering commands is discussed. A nonlinear programming (NLP) algorithm that is designed to solve a very general problem has the potential to address the diversity demanded by future launch systems. Using B-splines for the command functional form allows the NLP algorithm to adjust the shape of the command profile to achieve optimal performance. The algorithm flexibility is demonstrated by simulation of ascent with dynamic loading constraints through a set of random wind profiles with and without wind sensing capability.

  13. Investigation into the geometric consequences of processing substantially compressed images

    NASA Astrophysics Data System (ADS)

    Tempelmann, Udo; Nwosu, Zubbi; Zumbrunn, Roland M.

    1995-07-01

    One of the major driving forces behind digital photogrammetric systems is the continued drop in the cost of digital storage systems. However, terrestrial remote sensing systems continue to generate enormous volumes of data due to smaller pixels, larger coverage, and increased multispectral and multitemporal possibilities. Sophisticated compression algorithms have been developed but reduced visual quality of their output, which impedes object identification, and resultant geometric deformation have been limiting factors in employing compression. Compression and decompression time is also an issue but of less importance due to off-line possibilities. Two typical image blocks have been selected, one sub-block from a SPOT image and the other is an image of industrial targets taken with an off-the-shelf CCD. Three common compression algorithms have been chosen: JPEG, Wavelet, and Fractal. The images are run through the compression/decompression cycle, with parameter chosen to cover the whole range of available compression ratios. Points are identified on these images and their locations are compared against those in the originals. These results are presented to assist choice of compression facilities after considerations on metric quality against storage availability. Fractals offer the best visual quality but JPEG, closely followed by wavelets, imposes less geometric defects. JPEG seems to offer the best all-around performance when you consider geometric and visual quality, and compression/decompression speed.

  14. Flexible cryogenic conduit

    DOEpatents

    Brindza, Paul Daniel; Wines, Robin Renee; Takacs, James Joseph

    1999-01-01

    A flexible and relatively low cost cryogenic conduit is described. The flexible cryogenic conduit of the present invention comprises a first inner corrugated tube with single braided serving, a second outer corrugated tube with single braided serving concentric with the inner corrugated tube, and arranged outwardly about the periphery of the inner corrugated tube and between the inner and outer corrugated tubes: a superinsulation layer; a one half lap layer of polyester ribbon; a one half lap layer of copper ribbon; a spirally wound refrigeration tube; a second one half lap layer of copper ribbon; a second one half lap layer of polyester ribbon; a second superinsulation layer; a third one half lap layer of polyester ribbon; and a spirally wound stretchable and compressible filament.

  15. Flexible rotor dynamics analysis

    NASA Technical Reports Server (NTRS)

    Shen, F. A.

    1973-01-01

    A digital computer program was developed to analyze the general nonaxisymmetric and nonsynchronous transient and steady-state rotor dynamic performance of a bending- and shear-wise flexible rotor-bearing system under various operating conditions. The effects of rotor material mechanical hysteresis, rotor torsion flexibility, transverse effects of rotor axial and torsional loading and the anisotropic, in-phase and out-of-phase bearing stiffness and damping force and moment coefficients were included in the program to broaden its capability. An optimum solution method was found and incorporated in the computer program. Computer simulation of experimental data was made and qualitative agreements observed. The mathematical formulations, computer program verification, test data simulation, and user instruction was presented and discussed.

  16. Flexible cryogenic conduit

    SciTech Connect

    Brindza, P.D.; Wines, R.R.; Takacs, J.J.

    1999-12-21

    A flexible and relatively low cost cryogenic conduit is described. The flexible cryogenic conduit of the present invention comprises a first inner corrugated tube with single braided serving, a second outer corrugated tube with single braided serving concentric with the inner corrugated tube, and arranged outwardly about the periphery of the inner corrugated tube and between the inner and outer corrugated tubes: a superinsulation layer; a one half lap layer of polyester ribbon; a one half lap layer of copper ribbon; a spirally wound refrigeration tube; a second one half lap layer of copper ribbon; a second one half lap layer of polyester ribbon; a second superinsulation layer; a third one half lap layer of polyester ribbon; and a spirally wound stretchable and compressible filament.

  17. Control of flexible structures

    NASA Technical Reports Server (NTRS)

    Russell, R. A.

    1985-01-01

    The requirements for future space missions indicate that many of these spacecraft will be large, flexible, and in some applications, require precision geometries. A technology program that addresses the issues associated with the structure/control interactions for these classes of spacecraft is discussed. The goal of the NASA control of flexible structures technology program is to generate a technology data base that will provide the designer with options and approaches to achieve spacecraft performance such as maintaining geometry and/or suppressing undesired spacecraft dynamics. This technology program will define the appropriate combination of analysis, ground testing, and flight testing required to validate the structural/controls analysis and design tools. This work was motivated by a recognition that large minimum weight space structures will be required for many future missions. The tools necessary to support such design included: (1) improved structural analysis; (2) modern control theory; (3) advanced modeling techniques; (4) system identification; and (5) the integration of structures and controls.

  18. PTFE films with improved flexibility

    NASA Technical Reports Server (NTRS)

    Muraca, R. F.; Koch, A. A.

    1972-01-01

    Development and application of flexible polytetrafluroethylene films for expulsion bladders in spacecraft propellant tanks are described. Flexibility of material is obtained by reducing crystallinity through annealing and quenching in water. Physical and mechanical properties of material are presented.

  19. Industrial Fuel Flexibility Workshop

    SciTech Connect

    none,

    2006-09-01

    On September 28, 2006, in Washington, DC, ITP and Booz Allen Hamilton conducted a fuel flexibility workshop with attendance from various stakeholder groups. Workshop participants included representatives from the petrochemical, refining, food and beverage, steel and metals, pulp and paper, cement and glass manufacturing industries; as well as representatives from industrial boiler manufacturers, technology providers, energy and waste service providers, the federal government and national laboratories, and developers and financiers.

  20. Assumed modes method and flexible multibody dynamics

    NASA Technical Reports Server (NTRS)

    Tadikonda, S. S. K.; Mordfin, T. G.; Hu, T. G.

    1993-01-01

    The use of assumed modes in flexible multibody dynamics algorithms requires the evaluation of several domain dependent integrals that are affected by the type of modes used. The implications of these integrals - often called zeroth, first and second order terms - are investigated in this paper, for arbitrarily shaped bodies. Guidelines are developed for the use of appropriate boundary conditions while generating the component modal models. The issue of whether and which higher order terms must be retained is also addressed. Analytical results, and numerical results using the Shuttle Remote Manipulator System as the multibody system, are presented to qualitatively and quantitatively address these issues.

  1. Flexible materials technology

    NASA Technical Reports Server (NTRS)

    Steurer, W. H.

    1980-01-01

    A survey of all presently defined or proposed large space systems indicated an ever increasing demand for flexible components and materials, primarily as a result of the widening disparity between the stowage space of launch vehicles and the size of advanced systems. Typical flexible components and material requirements were identified on the basis of recurrence and/or functional commonality. This was followed by the evaluation of candidate materials and the search for material capabilities which promise to satisfy the postulated requirements. Particular attention was placed on thin films, and on the requirements of deployable antennas. The assessment of the performance of specific materials was based primarily on the failure mode, derived from a detailed failure analysis. In view of extensive on going work on thermal and environmental degradation effects, prime emphasis was placed on the assessment of the performance loss by meteoroid damage. Quantitative data were generated for tension members and antenna reflector materials. A methodology was developed for the representation of the overall materials performance as related to systems service life. A number of promising new concepts for flexible materials were identified.

  2. RF Sputtering for preparing substantially pure amorphous silicon monohydride

    DOEpatents

    Jeffrey, Frank R.; Shanks, Howard R.

    1982-10-12

    A process for controlling the dihydride and monohydride bond densities in hydrogenated amorphous silicon produced by reactive rf sputtering of an amorphous silicon target. There is provided a chamber with an amorphous silicon target and a substrate therein with the substrate and the target positioned such that when rf power is applied to the target the substrate is in contact with the sputtering plasma produced thereby. Hydrogen and argon are fed to the chamber and the pressure is reduced in the chamber to a value sufficient to maintain a sputtering plasma therein, and then rf power is applied to the silicon target to provide a power density in the range of from about 7 watts per square inch to about 22 watts per square inch to sputter an amorphous silicon hydride onto the substrate, the dihydride bond density decreasing with an increase in the rf power density. Substantially pure monohydride films may be produced.

  3. Borehole survey method and apparatus for drilling substantially horizontal boreholes

    SciTech Connect

    Trowsdale, L.S.

    1982-11-30

    A borehole survey method and apparatus are claimed for use in drilling substantially horizontal boreholes through a mineral deposit wherein a dip accelerometer, a roll accelerometer assembly and a fluxgate are disposed near the drill bit, which is mounted on a bent sub, and connected to a surface computation and display unit by a cable which extends through the drill string. The dip angle of the borehole near the drill bit, the azimuth of the borehole near the drill bit and the roll angle or orientation of the bent sub are measured and selectively displayed at the surface while the drill string is in the borehole for utilization in guiding the drill bit through the mineral deposit along a predetermined path.

  4. Clozapine-induced dysphagia with secondary substantial weight loss.

    PubMed

    Osman, Mugtaba; Devadas, Vekneswaran

    2016-01-01

    Dysphagia is listed as a 'rare' side effect following clozapine treatment. In this case report, we describe how significant clozapine-induced dysphagia has led to significant reduction of nutritional intake with subsequent substantial weight loss. An 18-year-old single man with an established diagnosis of treatment-resistant paranoid schizophrenia recovered well on a therapeutic dose of clozapine. However, he was noted to lose weight significantly (up to 20% of his original weight) as the dose was uptitrated. This was brought about by development of dysphagia, likely to be due to clozapine. Addition of nutritional supplementary liquids and initiation of a modified behavioural dietary/swallowing programme, while repeatedly mastering the Mendelsohn manoeuvre technique, alleviated the swallowing difficulties and restored his weight. PMID:27543610

  5. Resonant infrared detector with substantially unit quantum efficiency

    NASA Technical Reports Server (NTRS)

    Farhoomand, Jam (Inventor); Mcmurray, Robert E., Jr. (Inventor)

    1994-01-01

    A resonant infrared detector includes an infrared-active layer which has first and second parallel faces and which absorbs radiation of a given wavelength. The detector also includes a first tuned reflective layer, disposed opposite the first face of the infrared-active layer, which reflects a specific portion of the radiation incident thereon and allows a specific portion of the incident radiation at the given wavelength to reach the infrared-active layer. A second reflective layer, disposed opposite the second face of the infrared-active layer, reflects back into the infrared-active layer substantially all of the radiation at the given wavelength which passes through the infrared-active layer. The reflective layers have the effect of increasing the quantum efficiency of the infrared detector relative to the quantum efficiency of the infrared-active layer alone.

  6. Method and apparatus for a substantially coaxial injector element

    NASA Technical Reports Server (NTRS)

    Horn, Mark D. (Inventor); Miyata, Shinjiro (Inventor); Farhangi, Shahram (Inventor)

    2006-01-01

    A system to provide a two piece robust fluid injector. According to various embodiments, the fluid injector is a fuel injector for a combustion engine. The injector includes two coaxially formed annuluses. One annulus is formed in a face plate and the second annulus or hole is defined by a tube extending through the face plate. The tube extends through the face plate in a portion of a through bore which also is used to define the second annulus. The second annulus is formed using a throughbore through which the tube extends. This allows the second annulus to always be formed inherently and precisely substantially coaxial with the first annulus. Moreover, the second annulus can be formed with a much greater tolerance than if other independent components needed to be added.

  7. Flexible Multi-Shock Shield

    NASA Technical Reports Server (NTRS)

    Christiansen, Eric L. (Inventor); Crews, Jeanne L. (Inventor)

    2005-01-01

    Flexible multi-shock shield system and method are disclosed for defending against hypervelocity particles. The flexible multi-shock shield system and method may include a number of flexible bumpers or shield layers spaced apart by one or more resilient support layers, all of which may be encapsulated in a protective cover. Fasteners associated with the protective cover allow the flexible multi-shock shield to be secured to the surface of a structure to be protected.

  8. Portable Health Algorithms Test System

    NASA Technical Reports Server (NTRS)

    Melcher, Kevin J.; Wong, Edmond; Fulton, Christopher E.; Sowers, Thomas S.; Maul, William A.

    2010-01-01

    A document discusses the Portable Health Algorithms Test (PHALT) System, which has been designed as a means for evolving the maturity and credibility of algorithms developed to assess the health of aerospace systems. Comprising an integrated hardware-software environment, the PHALT system allows systems health management algorithms to be developed in a graphical programming environment, to be tested and refined using system simulation or test data playback, and to be evaluated in a real-time hardware-in-the-loop mode with a live test article. The integrated hardware and software development environment provides a seamless transition from algorithm development to real-time implementation. The portability of the hardware makes it quick and easy to transport between test facilities. This hard ware/software architecture is flexible enough to support a variety of diagnostic applications and test hardware, and the GUI-based rapid prototyping capability is sufficient to support development execution, and testing of custom diagnostic algorithms. The PHALT operating system supports execution of diagnostic algorithms under real-time constraints. PHALT can perform real-time capture and playback of test rig data with the ability to augment/ modify the data stream (e.g. inject simulated faults). It performs algorithm testing using a variety of data input sources, including real-time data acquisition, test data playback, and system simulations, and also provides system feedback to evaluate closed-loop diagnostic response and mitigation control.

  9. Current Issues in Flexibility Fitness.

    ERIC Educational Resources Information Center

    Knudson, Duane V.; Magnusson, Peter; McHugh, Malachy

    2000-01-01

    Physical activity is extremely important in maintaining good health. Activity is not possible without a certain amount of flexibility. This report discusses issues related to flexibility fitness. Flexibility is a property of the musculoskeletal system that determines the range of motion achievable without injury to the joints. Static flexibility…

  10. Flexible Scheduling: Making the Transition

    ERIC Educational Resources Information Center

    Creighton, Peggy Milam

    2008-01-01

    Citing literature that supports the benefits of flexible scheduling on student achievement, the author exhorts readers to campaign for flexible scheduling in their library media centers. She suggests tips drawn from the work of Graziano (2002), McGregor (2006) and Stripling (1997) for making a smooth transition from fixed to flexible scheduling:…

  11. Navigation system for flexible endoscopes

    NASA Astrophysics Data System (ADS)

    Hummel, Johann; Figl, Michael; Birkfellner, Wolfgang; Häfner, Michael; Kollmann, Christian; Bergmann, Helmar

    2003-05-01

    Endoscopic Ultrasound (EUS) features flexible endoscopes equipped with a radial or linear array scanhead allowing high resolution examination of organs adjacent to the upper gastrointestinal tract. An optical system based on fibre-glass or a CCD-chip allows additional orientation. However, 3-dimensional orientation and correct identification of the various anatomical structures may be difficult. It therefore seems desirable to merge real-time US images with high resolution CT or MR images acquired prior to EUS to simplify navigation during the intervention. The additional information provided by CT or MR images might facilitate diagnosis of tumors and, ultimately, guided puncture of suspicious lesions. We built a grid with 15 plastic spheres and measured their positions relatively to five fiducial markers placed on the top of the grid. For this measurement we used an optical tracking system (OTS) (Polaris, NDI, Can). Two sensors of an electromagnetic tracking system (EMTS) (Aurora, NDI, Can) were mounted on a flexible endoscope (Pentax GG 38 UX, USA) to enable a free hand ultrasound calibration. To determine the position of the plastic spheres in the emitter coordinate system of the EMTS we applied a point-to-point registration (Horn) using the coordinates of the fiducial markers in both coordinate systems (OTS and EMTS). For the transformation between EMTS to the CT space the Horn algorithm was adopted again using the fiducial markers. Visualization was enabled by the use of the AVW-4.0 library (Biomedical Imaging Resource, Mayo Clinic, Rochester/MN, USA). To evaluate the suitability of our new navigation system we measured the Fiducial Registration Error (FRE) of the diverse registrations and the Target Registration Error (TRE) for the complete transformation from the US space to the CT space. The FRE for the ultrasound calibration amounted to 4.3 mm +/- 4.2 mm, resulting from 10 calibration procedures. For the transformation from the OTS reference system to the

  12. Actuator Grouping Optimization on Flexible Space Reflectors

    NASA Technical Reports Server (NTRS)

    Hill, Jeffrey R.; Wang, K. W.; Fang, Houfei; Quijano, Ubaldo

    2011-01-01

    With the rapid advances in deployable membrane and mesh antenna technologies, the feasibility of developing large, lightweight reflectors has greatly improved. In order to achieve the required surface accuracy, precision surface control is needed on these lightweight reflectors. For this study, an analytical model is shown which combines a flexible Kapton reflector with Polyvinylidene fluoride (PVDF) actuators for surface control. Surface errors are introduced that are similar to real world scenarios, and a least squares control algorithm is developed for surface control. Experimental results on a 2.4 meter reflector show that while the analytical reflector model is generally correct, due to idiosyncrasies in the reflector it cannot be used for online control. A new method called the En Mass Elimination algorithm is used to determine the optimal grouping of actuators when the number of actuators in the system exceeds the number of power supplies available.

  13. Control of resonance phenomenon in flexible structures via active support

    NASA Astrophysics Data System (ADS)

    Tavakolpour Saleh, A. R.; Mailah, M.

    2012-07-01

    This paper introduces the concept of active support to cope with the resonance phenomenon in the flexible structures. A valid computational platform for the flexible structure was first presented via a finite difference (FD) approach. Then, the active support mechanism was applied to the simulation algorithm through which the performance of the proposed methodology in suppressing the resonance phenomenon was evaluated. The flexible structure was thus excited with the external disturbance and the system response with and without the effect of the active support was investigated through a simulation study. The simulation outcomes clearly demonstrated effective resonance suppression in the flexible structure. Finally, an experimental rig was developed to investigate the validity of the proposed technique. The experimental results revealed an acceptable agreement with the simulation outcomes through which the validity of the proposed control method was affirmed.

  14. Analyses of substantially different plasma current densities and safety factors reconstructed from magnetic diagnostics data

    NASA Astrophysics Data System (ADS)

    Zaitsev, F. S.; Kostomarov, D. P.; Suchkov, E. P.; Drozdov, V. V.; Solano, E. R.; Murari, A.; Matejcik, S.; Hawkes, N. C.; Contributors, JET-EFDA

    2011-10-01

    The problem of plasma current density and safety factor reconstruction using magnetic field measurements is considered. In the traditional formulation, the problem is strongly ill-posed. In particular, substantially different current densities and safety factors can be equally well attributed to the same set of measurements, given their experimental errors. In other words, the problem can be strongly unstable with respect to the input data. Different constraints are used in practice to make the problem more stable. This paper presents an accurate mathematical formulation of the inverse problem and its variants. A numerical algorithm is provided, which permits us to study the stability with respect to variations in the input data, to find all substantially different solutions, or to prove their absence, and to determine the confidence intervals of the reconstructions. The proposed method also allows establishing the maximum error for a given diagnostic (additional constraint), below which the diagnostic efficiently extracts one solution among several substantially different ones. Examples of very different current density and safety factor reconstructions for measurements with finite accuracy are presented for the original formulation of the inverse problem. Cases of MAST, JET and ITER-like plasmas are considered. It is shown that including the motional Stark effect (MSE) measurements as a constraint, provided the accuracy of MSE measurements is sufficient, allows identifying one solution among several very different ones, obtained without such a constraint. The maximum MSE diagnostics error for efficient identification of this solution is estimated for JET. The approach of this paper can be used for a wide range of ill-posed problems in physics and can help in selecting additional conditions, which can identify the most likely solution among several.

  15. The flexible nature of unconscious cognition.

    PubMed

    Wokke, Martijn E; van Gaal, Simon; Scholte, H Steven; Ridderinkhof, K Richard; Lamme, Victor A F

    2011-01-01

    The cognitive signature of unconscious processes is hotly debated recently. Generally, consciousness is thought to mediate flexible, adaptive and goal-directed behavior, but in the last decade unconscious processing has rapidly gained ground on traditional conscious territory. In this study we demonstrate that the scope and impact of unconscious information on behavior and brain activity can be modulated dynamically on a trial-by-trial basis. Participants performed a Go/No-Go experiment in which an unconscious (masked) stimulus preceding a conscious target could be associated with either a Go or No-Go response. Importantly, the mapping of stimuli onto these actions varied on a trial-by-trial basis, preventing the formation of stable associations and hence the possibility that unconscious stimuli automatically activate these control actions. By eliminating stimulus-response associations established through practice we demonstrate that unconscious information can be processed in a flexible and adaptive manner. In this experiment we show that the same unconscious stimulus can have a substantially different effect on behavior and (prefrontal) brain activity depending on the rapidly changing task context in which it is presented. This work suggests that unconscious information processing shares many sophisticated characteristics (including flexibility and context-specificity) with its conscious counterpart. PMID:21980530

  16. Neutron star glitches have a substantial minimum size

    NASA Astrophysics Data System (ADS)

    Espinoza, C. M.; Antonopoulou, D.; Stappers, B. W.; Watts, A.; Lyne, A. G.

    2014-05-01

    Glitches are sudden spin-up events that punctuate the steady spin-down of pulsars and are thought to be due to the presence of a superfluid component within neutron stars. The precise glitch mechanism and its trigger, however, remain unknown. The size of glitches is a key diagnostic for models of the underlying physics. While the largest glitches have long been taken into account by theoretical models, it has always been assumed that the minimum size lay below the detectability limit of the measurements. In this paper we define general glitch detectability limits and use them on 29 yr of daily observations of the Crab pulsar, carried out at Jodrell Bank Observatory. We find that all glitches lie well above the detectability limits and by using an automated method to search for small events we are able to uncover the full glitch size distribution, with no biases. Contrary to the prediction of most models, the distribution presents a rapid decrease of the number of glitches below ˜0.05 μHz. This substantial minimum size indicates that a glitch must involve the motion of at least several billion superfluid vortices and provides an extra observable which can greatly help the identification of the trigger mechanism. Our study also shows that glitches are clearly separated from all the other rotation irregularities. This supports the idea that the origin of glitches is different to that of timing noise, which comprises the unmodelled random fluctuations in the rotation rates of pulsars.

  17. Familial Influences on Recantation in Substantiated Child Sexual Abuse Cases.

    PubMed

    Malloy, Lindsay C; Mugno, Allison P; Rivard, Jillian R; Lyon, Thomas D; Quas, Jodi A

    2016-08-01

    The underlying reasons for recantation in children's disclosure of child sexual abuse (CSA) have been debated in recent years. In the present study, we examined the largest sample of substantiated CSA cases involving recantations to date (n = 58 cases). We specifically matched those cases to 58 nonrecanters on key variables found to predict recantation in prior research (i.e., child age, alleged parent figure perpetrator, and caregiver unsupportiveness). Bivariate analyses revealed that children were less likely to recant when they were (1) initially removed from home postdisclosure and (2) initially separated from siblings postdisclosure. Multivariate analyses revealed that children were less likely to recant when family members (other than the nonoffending caregiver) expressed belief in the children's allegations and more likely to recant when family members (other than the nonoffending caregiver) expressed disbelief in the allegations and when visitations with the alleged perpetrator were recommended at their first hearing. Results have implications for understanding the complex ways in which social processes may motivate some children to retract previous reports of sexual abuse. PMID:27234520

  18. Process for preparing superconducting film having substantially uniform phase development

    DOEpatents

    Bharacharya, Raghuthan; Parilla, Philip A.; Blaugher, Richard D.

    1995-01-01

    A process for preparing a superconducting film, such as a thallium-barium-calcium-copper oxide superconducting film, having substantially uniform phase development. The process comprises providing an electrodeposition bath having one or more soluble salts of one or more respective potentially superconducting metals in respective amounts adequate to yield a superconducting film upon subsequent appropriate treatment. Should all of the metals required for producing a superconducting film not be made available in the bath, such metals can be a part of the ambient during a subsequent annealing process. A soluble silver salt in an amount between about 0.1% and about 4.0% by weight of the provided other salts is also provided to the bath, and the bath is electrically energized to thereby form a plated film. The film is annealed in ambient conditions suitable to cause formation of a superconductor film. Doping with silver reduces the temperature at which the liquid phase appears during the annealing step, initiates a liquid phase throughout the entire volume of deposited material, and influences the nucleation and growth of the deposited material.

  19. Process for preparing superconducting film having substantially uniform phase development

    DOEpatents

    Bharacharya, R.; Parilla, P.A.; Blaugher, R.D.

    1995-12-19

    A process is disclosed for preparing a superconducting film, such as a thallium-barium-calcium-copper oxide superconducting film, having substantially uniform phase development. The process comprises providing an electrodeposition bath having one or more soluble salts of one or more respective potentially superconducting metals in respective amounts adequate to yield a superconducting film upon subsequent appropriate treatment. Should all of the metals required for producing a superconducting film not be made available in the bath, such metals can be a part of the ambient during a subsequent annealing process. A soluble silver salt in an amount between about 0.1% and about 4.0% by weight of the provided other salts is also provided to the bath, and the bath is electrically energized to thereby form a plated film. The film is annealed in ambient conditions suitable to cause formation of a superconductor film. Doping with silver reduces the temperature at which the liquid phase appears during the annealing step, initiates a liquid phase throughout the entire volume of deposited material, and influences the nucleation and growth of the deposited material. 3 figs.

  20. Substantial proportion of global streamflow less than three months old

    NASA Astrophysics Data System (ADS)

    Jasechko, Scott; Kirchner, James W.; Welker, Jeffrey M.; McDonnell, Jeffrey J.

    2016-02-01

    Biogeochemical cycles, contaminant transport and chemical weathering are regulated by the speed at which precipitation travels through landscapes and reaches streams. Streamflow is a mixture of young and old precipitation, but the global proportions of these young and old components are not known. Here we analyse seasonal cycles of oxygen isotope ratios in rain, snow and streamflow compiled from 254 watersheds around the world, and calculate the fraction of streamflow that is derived from precipitation that fell within the past two or three months. This young streamflow accounts for about a third of global river discharge, and comprises at least 5% of discharge in about 90% of the catchments we investigated. We conclude that, although typical catchments have mean transit times of years or even decades, they nonetheless can rapidly transmit substantial fractions of soluble contaminant inputs to streams. Young streamflow is less prevalent in steeper landscapes, which suggests they are characterized by deeper vertical infiltration. Because young streamflow is derived from less than 0.1% of global groundwater storage, we conclude that this thin veneer of aquifer storage will have a disproportionate influence on stream water quality.

  1. Substantial SNP-based heritability estimates for working memory performance

    PubMed Central

    Vogler, C; Gschwind, L; Coynel, D; Freytag, V; Milnik, A; Egli, T; Heck, A; de Quervain, D J-F; Papassotiropoulos, A

    2014-01-01

    Working memory (WM) is an important endophenotype in neuropsychiatric research and its use in genetic association studies is thought to be a promising approach to increase our understanding of psychiatric disease. As for any genetically complex trait, demonstration of sufficient heritability within the specific study context is a prerequisite for conducting genetic studies of that trait. Recently developed methods allow estimating trait heritability using sets of common genetic markers from genome-wide association study (GWAS) data in samples of unrelated individuals. Here we present single-nucleotide polymorphism (SNP)-based heritability estimates (h2SNP) for a WM phenotype. A Caucasian sample comprising a total of N=2298 healthy and young individuals was subjected to an N-back WM task. We calculated the genetic relationship between all individuals on the basis of genome-wide SNP data and performed restricted maximum likelihood analyses for variance component estimation to derive the h2SNP estimates. Heritability estimates for three 2-back derived WM performance measures based on all autosomal chromosomes ranged between 31 and 41%, indicating a substantial SNP-based heritability for WM traits. These results indicate that common genetic factors account for a prominent part of the phenotypic variation in WM performance. Hence, the application of GWAS on WM phenotypes is a valid method to identify the molecular underpinnings of WM. PMID:25203169

  2. Rotating flexible drag mill

    DOEpatents

    Pepper, W.B.

    1984-05-09

    A rotating parachute for decelerating objects travelling through atmosphere at subsonic or supersonic deployment speeds includes a circular canopy having a plurality of circumferentially arranged flexible panels projecting radially from a solid central disk. A slot extends radially between adjacent panels to the outer periphery of the canopy. Upon deployment, the solid disk diverts air radially to rapidly inflate the panels into a position of maximum diameter. Air impinging on the panels adjacent the panel slots rotates the parachute during its descent. Centrifugal force flattens the canopy into a constant maximum diameter during terminal descent for maximum drag and deceleration.

  3. Composite Flexible Blanket Insulation

    NASA Technical Reports Server (NTRS)

    Kourtides, Demetrius A. (Inventor); Pitts, William C. (Inventor); Goldstein, Howard E. (Inventor); Sawko, Paul M. (Inventor)

    1991-01-01

    Composite flexible multilayer insulation systems (MLI) were evaluated for thermal performance and compared with the currently used fibrous silica (baseline) insulation system. The systems described are multilayer insulations consisting of alternating layers of metal foil and scrim ceramic cloth or vacuum metallized polymeric films quilted together using ceramic thread. A silicon carbide thread for use in the quilting and the method of making it are also described. These systems are useful in providing lightweight insulation for a variety of uses, particularly on the surface of aerospace vehicles subject to very high temperatures during flight.

  4. A flexible business focus

    SciTech Connect

    Hennagir, T.

    1994-11-01

    The challenge of sourcing equipment to meet customer needs around the world remains a prerequisite for boiler and CFB manufacturers as they strive to maintain a strong business presence in key markets. Boiler vendors are learning to meet their targets based upon what the market is, not what they hope it will become. An elastic equipment supply strategy is bolstering new business activity for internationally active boiler and circulating fluidized bed combustion (CFB) vendors. Techniques such as flexible sourcing and expanded scope capability are helping suppliers gain market advantage in new global growth areas.

  5. Flexible composite radiation detector

    DOEpatents

    Cooke, D. Wayne; Bennett, Bryan L.; Muenchausen, Ross E.; Wrobleski, Debra A.; Orler, Edward B.

    2006-12-05

    A flexible composite scintillator was prepared by mixing fast, bright, dense rare-earth doped powdered oxyorthosilicate (such as LSO:Ce, LSO:Sm, and GSO:Ce) scintillator with a polymer binder. The binder is transparent to the scintillator emission. The composite is seamless and can be made large and in a wide variety of shapes. Importantly, the composite can be tailored to emit light in a spectral region that matches the optimum response of photomultipliers (about 400 nanometers) or photodiodes (about 600 nanometers), which maximizes the overall detector efficiency.

  6. Flexible Volumetric Structure

    NASA Technical Reports Server (NTRS)

    Cagle, Christopher M. (Inventor); Schlecht, Robin W. (Inventor)

    2014-01-01

    A flexible volumetric structure has a first spring that defines a three-dimensional volume and includes a serpentine structure elongatable and compressible along a length thereof. A second spring is coupled to at least one outboard edge region of the first spring. The second spring is a sheet-like structure capable of elongation along an in-plane dimension thereof. The second spring is oriented such that its in-plane dimension is aligned with the length of the first spring's serpentine structure.

  7. Flexible Material Systems Testing

    NASA Technical Reports Server (NTRS)

    Lin, John K.; Shook, Lauren S.; Ware, Joanne S.; Welch, Joseph V.

    2010-01-01

    An experimental program has been undertaken to better characterize the stress-strain characteristics of flexible material systems to support a NASA ground test program for inflatable decelerator material technology. A goal of the current study is to investigate experimental methods for the characterization of coated woven material stiffness. This type of experimental mechanics data would eventually be used to define the material inputs of fluid-structure interaction simulation models. The test methodologies chosen for this stress-strain characterization are presented along with the experimental results.

  8. Parallel processing environment for multi-flexible body dynamics

    NASA Technical Reports Server (NTRS)

    Venugopal, Ravi; Kumar, Manoj N.; Singh, Ramen P.; Taylor, Lawrence W., Jr.

    1989-01-01

    The implementation of a dynamics solution algorithm with inherent parallelism which is applicable to the dynamics of large flexible space structures is described. The algorithm is unique in that parts of the solution can be computed simultaneously by working with different branches of its tree topology. The algorithm exhibits close to 0(n) type behavior. The data flow within the solution algorithm is discussed along with results from its implementation in a multiprocessing environment. A model of the United States Space Station is used as an example. The results show that, with fast multiple scalar processors, an efficient algorithm, and symbolically generated equations of motion, real-time performance can be achieved with present-day hardware technology, even with complex dynamical models.

  9. A flexible self-learning model based on granular computing

    NASA Astrophysics Data System (ADS)

    Wei, Ting; Wu, Yu; Li, Yinguo

    2007-04-01

    Granular Computing(GrC) is an emerging theory which simulates the process of human brain understanding and solving problems. Rough set theory is a tool for dealing with uncertainty and vagueness aspects of knowledge model. SMLGrC algorithm introduces GrC to classical rough set algorithms, and makes the length of the rules relatively short but it can not process mass data sets. In order to solve this problem, based on the analysis of the hierarchical granular model of information table, the method of Granular Distribution List(GDL) is introduced to generate granule, and a granular computing algorithm(SLMGrC) is improved. Sample Covered Factor(SCF) is also introduced to control the generation of rules when the algorithm generates conflicting rules. The improved algorithm can process mass data sets directly without influencing the validity of SLMGrC. Experiments demonstrated the validity and flexibility of our method.

  10. A flexible approach to distributed data anonymization.

    PubMed

    Kohlmayer, Florian; Prasser, Fabian; Eckert, Claudia; Kuhn, Klaus A

    2014-08-01

    Sensitive biomedical data is often collected from distributed sources, involving different information systems and different organizational units. Local autonomy and legal reasons lead to the need of privacy preserving integration concepts. In this article, we focus on anonymization, which plays an important role for the re-use of clinical data and for the sharing of research data. We present a flexible solution for anonymizing distributed data in the semi-honest model. Prior to the anonymization procedure, an encrypted global view of the dataset is constructed by means of a secure multi-party computing (SMC) protocol. This global representation can then be anonymized. Our approach is not limited to specific anonymization algorithms but provides pre- and postprocessing for a broad spectrum of algorithms and many privacy criteria. We present an extensive analytical and experimental evaluation and discuss which types of methods and criteria are supported. Our prototype demonstrates the approach by implementing k-anonymity, ℓ-diversity, t-closeness and δ-presence with a globally optimal de-identification method in horizontally and vertically distributed setups. The experiments show that our method provides highly competitive performance and offers a practical and flexible solution for anonymizing distributed biomedical datasets. PMID:24333850

  11. Protein-protein docking with backbone flexibility.

    PubMed

    Wang, Chu; Bradley, Philip; Baker, David

    2007-10-19

    Computational protein-protein docking methods currently can create models with atomic accuracy for protein complexes provided that the conformational changes upon association are restricted to the side chains. However, it remains very challenging to account for backbone conformational changes during docking, and most current methods inherently keep monomer backbones rigid for algorithmic simplicity and computational efficiency. Here we present a reformulation of the Rosetta docking method that incorporates explicit backbone flexibility in protein-protein docking. The new method is based on a "fold-tree" representation of the molecular system, which seamlessly integrates internal torsional degrees of freedom and rigid-body degrees of freedom. Problems with internal flexible regions ranging from one or more loops or hinge regions to all of one or both partners can be readily treated using appropriately constructed fold trees. The explicit treatment of backbone flexibility improves both sampling in the vicinity of the native docked conformation and the energetic discrimination between near-native and incorrect models. PMID:17825317

  12. Flexible multiply towpreg and method of production therefor

    NASA Technical Reports Server (NTRS)

    Muzzy, John D. (Inventor); Varughese, Babu (Inventor)

    1992-01-01

    This invention relates to an improved flexible towpreg and a method of production therefor. The improved flexible towpreg comprises a plurality of towpreg plies which comprise reinforcing filaments and matrix forming material; the reinforcing filaments being substantially wetout by the matrix forming material such that the towpreg plies are substantially void-free composite articles, and the towpreg plies having an average thickness less than about 100 microns. The method of production for the improved flexible towpreg comprises the steps of spreading the reinforcing filaments to expose individually substantially all of the reinforcing filaments; coating the reinforcing filaments with the matrix forming material in a manner causing interfacial adhesion of the matrix forming material to the reinforcing filaments; forming the towpreg plies by heating the matrix forming material contacting the reinforcing filaments until the matrix forming material liquefies and coats the reinforcing filaments; and cooling the towpreg plies in a manner such that substantial cohesion between neighboring towpreg plies is prevented until the matrix forming material solidifies.

  13. Asymmetric Flexible Supercapacitor Stack

    PubMed Central

    2008-01-01

    Electrical double layer supercapacitor is very significant in the field of electrical energy storage which can be the solution for the current revolution in the electronic devices like mobile phones, camera flashes which needs flexible and miniaturized energy storage device with all non-aqueous components. The multiwalled carbon nanotubes (MWNTs) have been synthesized by catalytic chemical vapor deposition technique over hydrogen decrepitated Mischmetal (Mm) based AB3alloy hydride. The polymer dispersed MWNTs have been obtained by insitu polymerization and the metal oxide/MWNTs were synthesized by sol-gel method. Morphological characterizations of polymer dispersed MWNTs have been carried out using scanning electron microscopy (SEM), transmission electron microscopy (TEM and HRTEM). An assymetric double supercapacitor stack has been fabricated using polymer/MWNTs and metal oxide/MWNTs coated over flexible carbon fabric as electrodes and nafion®membrane as a solid electrolyte. Electrochemical performance of the supercapacitor stack has been investigated using cyclic voltammetry, galvanostatic charge-discharge, and electrochemical impedance spectroscopy.

  14. Substantial Alterations of the Cutaneous Bacterial Biota in Psoriatic Lesions

    PubMed Central

    Gao, Zhan; Tseng, Chi-hong; Strober, Bruce E.; Pei, Zhiheng; Blaser, Martin J.

    2008-01-01

    For psoriasis, an idiopathic inflammatory disorder of the skin, the microbial biota has not been defined using cultivation-independent methods. We used broad-range 16S rDNA PCR for archaea and bacteria to examine the microbiota of normal and psoriatic skin. From 6 patients, 19 cutaneous samples (13 from diseased skin and 6 from normal skin) were obtained. Extracted DNA was subjected to the broad range PCR, and 1,925 cloned products were compared with 2,038 products previously reported from healthy persons. Using 98% sequence identity as a species boundary, 1,841 (95.6%) clones were similar to known bacterial 16S rDNA, representing 6 phyla, 86 genera, or 189 species-level operational taxonomic unit (SLOTU); 84 (4.4%) clones with <98% identity probably represented novel species. The most abundant and diverse phylum populating the psoriatic lesions was Firmicutes (46.2%), significantly (P<0.001) overrepresented, compared to the samples from uninvolved skin of the patients (39.0%) and healthy persons (24.4%). In contrast, Actinobacteria, the most prevalent and diverse phylum in normal skin samples from both healthy persons (47.6%) and the patients (47.8%), was significantly (P<0.01) underrepresented in the psoriatic lesion samples (37.3%). Representation of Propionibacterium species were lower in the psoriatic lesions (2.9±5.5%) than from normal persons (21.1±18.2%; P<0.001), whereas normal skin from the psoriatic patients showed intermediate levels (12.3±21.6%). We conclude that psoriasis is associated with substantial alteration in the composition and representation of the cutaneous bacterial biota. PMID:18648509

  15. Algorithm development

    NASA Technical Reports Server (NTRS)

    Barth, Timothy J.; Lomax, Harvard

    1987-01-01

    The past decade has seen considerable activity in algorithm development for the Navier-Stokes equations. This has resulted in a wide variety of useful new techniques. Some examples for the numerical solution of the Navier-Stokes equations are presented, divided into two parts. One is devoted to the incompressible Navier-Stokes equations, and the other to the compressible form.

  16. Transient dynamics of a flexible rotor with squeeze film dampers

    NASA Technical Reports Server (NTRS)

    Buono, D. F.; Schlitzer, L. D.; Hall, R. G., III; Hibner, D. H.

    1978-01-01

    A series of simulated blade loss tests are reported on a test rotor designed to operate above its second bending critical speed. A series of analyses were performed which predicted the transient behavior of the test rig for each of the blade loss tests. The scope of the program included the investigation of transient rotor dynamics of a flexible rotor system, similar to modern flexible jet engine rotors, both with and without squeeze film dampers. The results substantiate the effectiveness of squeeze film dampers and document the ability of available analytical methods to predict their effectiveness and behavior.

  17. Flexible time domain averaging technique

    NASA Astrophysics Data System (ADS)

    Zhao, Ming; Lin, Jing; Lei, Yaguo; Wang, Xiufeng

    2013-09-01

    Time domain averaging(TDA) is essentially a comb filter, it cannot extract the specified harmonics which may be caused by some faults, such as gear eccentric. Meanwhile, TDA always suffers from period cutting error(PCE) to different extent. Several improved TDA methods have been proposed, however they cannot completely eliminate the waveform reconstruction error caused by PCE. In order to overcome the shortcomings of conventional methods, a flexible time domain averaging(FTDA) technique is established, which adapts to the analyzed signal through adjusting each harmonic of the comb filter. In this technique, the explicit form of FTDA is first constructed by frequency domain sampling. Subsequently, chirp Z-transform(CZT) is employed in the algorithm of FTDA, which can improve the calculating efficiency significantly. Since the signal is reconstructed in the continuous time domain, there is no PCE in the FTDA. To validate the effectiveness of FTDA in the signal de-noising, interpolation and harmonic reconstruction, a simulated multi-components periodic signal that corrupted by noise is processed by FTDA. The simulation results show that the FTDA is capable of recovering the periodic components from the background noise effectively. Moreover, it can improve the signal-to-noise ratio by 7.9 dB compared with conventional ones. Experiments are also carried out on gearbox test rigs with chipped tooth and eccentricity gear, respectively. It is shown that the FTDA can identify the direction and severity of the eccentricity gear, and further enhances the amplitudes of impulses by 35%. The proposed technique not only solves the problem of PCE, but also provides a useful tool for the fault symptom extraction of rotating machinery.

  18. Investigation of Boundary Conditions for Flexible Multibody Spacecraft Dynamics

    NASA Technical Reports Server (NTRS)

    MacLean, John R.; Huynh, An; Quiocho, Leslie J.

    2007-01-01

    In support of both the Space Shuttle and International Space Station programs, a set of generic multibody dynamics algorithms integrated within the Trick simulation environment have addressed the variety of on-orbit manipulator simulation requirements for engineering analysis, procedures development and crew familiarization/training at the NASA Johnson Space Center (JSC). Enhancements to these dynamics algorithms are now being driven by a new set of Constellation program requirements for flexible multibody spacecraft simulation. One particular issue that has been discussed within the NASA community is the assumption of cantilever-type flexible body boundary conditions. This assumption has been commonly utilized within manipulator multibody dynamics formulations as it simplifies the computation of relative motion for articulated flexible topologies. Moreover, its use for modeling of space-based manipulators such as the Shuttle Remote Manipulator System (SRMS) and Space Station Remote Manipulator System (SSRMS) has been extensively validated against flight data. For more general flexible spacecraft applications, however, the assumption of cantilever-type boundary conditions may not be sufficient. This paper describes the boundary condition assumptions that were used in the original formulation, demonstrates that this formulation can be augmented to accommodate systems in which the assumption of cantilever boundary conditions no longer applies, and verifies the approach through comparison with an independent model previously validated against experimental hardware test data from a spacecraft flexible dynamics emulator.

  19. Generalized flexibility-rigidity index

    NASA Astrophysics Data System (ADS)

    Nguyen, Duc Duy; Xia, Kelin; Wei, Guo-Wei

    2016-06-01

    Flexibility-rigidity index (FRI) has been developed as a robust, accurate, and efficient method for macromolecular thermal fluctuation analysis and B-factor prediction. The performance of FRI depends on its formulations of rigidity index and flexibility index. In this work, we introduce alternative rigidity and flexibility formulations. The structure of the classic Gaussian surface is utilized to construct a new type of rigidity index, which leads to a new class of rigidity densities with the classic Gaussian surface as a special case. Additionally, we introduce a new type of flexibility index based on the domain indicator property of normalized rigidity density. These generalized FRI (gFRI) methods have been extensively validated by the B-factor predictions of 364 proteins. Significantly outperforming the classic Gaussian network model, gFRI is a new generation of methodologies for accurate, robust, and efficient analysis of protein flexibility and fluctuation. Finally, gFRI based molecular surface generation and flexibility visualization are demonstrated.

  20. Flexible transformation plasmonics using graphene.

    PubMed

    Lu, Wei Bing; Zhu, Wei; Xu, Hong Ju; Ni, Zhen Hua; Dong, Zheng Gao; Cui, Tie Jun

    2013-05-01

    The flexible control of surface plasmon polaritons (SPPs) is important and intriguing due to its wide application in novel plasmonic devices. Transformation optics (TO) offers the capability either to confine the SPP propagation on rigid curved/uneven surfaces, or to control the flow of SPPs on planar surfaces. However, TO has not permitted us to confine, manipulate, and control SPP waves on flexible curved surfaces. Here, we propose to confine and freely control flexible SPPs using TO and graphene. We show that SPP waves can be naturally confined and propagate on curved or uneven graphene surfaces with little bending and radiation losses, and the confined SPPs are further manipulated and controlled using TO. Flexible plasmonic devices are presented, including the bending waveguides, wave splitter, and Luneburg lens on curved surfaces. Together with the intrinsic flexibility, graphene can be served as a good platform for flexible transformation plasmonics. PMID:23669904

  1. FlexSnap: Flexible Non-sequential Protein Structure Alignment

    PubMed Central

    2010-01-01

    Background Proteins have evolved subject to energetic selection pressure for stability and flexibility. Structural similarity between proteins that have gone through conformational changes can be captured effectively if flexibility is considered. Topologically unrelated proteins that preserve secondary structure packing interactions can be detected if both flexibility and Sequential permutations are considered. We propose the FlexSnap algorithm for flexible non-topological protein structural alignment. Results The effectiveness of FlexSnap is demonstrated by measuring the agreement of its alignments with manually curated non-sequential structural alignments. FlexSnap showed competitive results against state-of-the-art algorithms, like DALI, SARF2, MultiProt, FlexProt, and FATCAT. Moreover on the DynDom dataset, FlexSnap reported longer alignments with smaller rmsd. Conclusions We have introduced FlexSnap, a greedy chaining algorithm that reports both sequential and non-sequential alignments and allows twists (hinges). We assessed the quality of the FlexSnap alignments by measuring its agreements with manually curated non-sequential alignments. On the FlexProt dataset, FlexSnap was competitive to state-of-the-art flexible alignment methods. Moreover, we demonstrated the benefits of introducing hinges by showing significant improvements in the alignments reported by FlexSnap for the structure pairs for which rigid alignment methods reported alignments with either low coverage or large rmsd. Availability An implementation of the FlexSnap algorithm will be made available online at http://www.cs.rpi.edu/~zaki/software/flexsnap. PMID:20047669

  2. Flexible retinal electrode array

    DOEpatents

    Okandan, Murat; Wessendorf, Kurt O.; Christenson, Todd R.

    2006-10-24

    An electrode array which has applications for neural stimulation and sensing. The electrode array can include a large number of electrodes each of which is flexibly attached to a common substrate using a plurality of springs to allow the electrodes to move independently. The electrode array can be formed from a combination of bulk and surface micromachining, with electrode tips that can include an electroplated metal (e.g. platinum, iridium, gold or titanium) or a metal oxide (e.g. iridium oxide) for biocompatibility. The electrode array can be used to form a part of a neural prosthesis, and is particularly well adapted for use in an implantable retinal prosthesis where the electrodes can be tailored to provide a uniform gentle contact pressure with optional sensing of this contact pressure at one or more of the electrodes.

  3. Flexible cloth seal assembly

    DOEpatents

    Bagepalli, Bharat Sampathkumar; Taura, Joseph Charles; Aksit, Mahmut Faruk; Demiroglu, Mehmet; Predmore, Daniel Ross

    1999-01-01

    A seal assembly having a flexible cloth seal which includes a shim assemblage surrounded by a cloth assemblage. A first tubular end portion, such as a gas turbine combustor, includes a longitudinal axis and has smooth and spaced-apart first and second surface portions defining a notch therebetween which is wider at its top than at its bottom and which extends outward from the axis. The second surface portion is outside curved, and a first edge of the cloth seal is positioned in the bottom of the notch. A second tubular end portion, such as a first stage nozzle, is located near, spaced apart from, and coaxially aligned with, the first tubular end portion. The second tubular end portion has a smooth third surface portion which surrounds at least a portion of the first tubular end portion and which is contacted by the cloth seal.

  4. Damped flexible seal

    DOEpatents

    DuBois, Neil J.; Amaral, Antonio M.

    1992-10-27

    A damped flexible seal assembly for a torpedo isolates the tailcone thereof rom vibrational energy present in the drive shaft assembly. A pair of outside flanges, each of which include an inwardly facing groove and an O-ring constrained therein, provide a watertight seal against the outer non-rotating surface of the drive shaft assembly. An inside flange includes an outwardly-facing groove and an O-ring constrained therein, and provides a watertight seal against the inner surface of the tail cone. Two cast-in-place elastomeric seals provide a watertight seal between the flanges and further provide a damping barrier between the outside flanges and the inside flanges for damping vibrational energy present in the drive shaft assembly before the energy can reach the tailcone through the seal assembly.

  5. Flexible cloth seal assembly

    DOEpatents

    Bagepalli, B.S.; Taura, J.C.; Aksit, M.F.; Demiroglu, M.; Predmore, D.R.

    1999-06-29

    A seal assembly is described having a flexible cloth seal which includes a shim assemblage surrounded by a cloth assemblage. A first tubular end portion, such as a gas turbine combustor, includes a longitudinal axis and has smooth and spaced-apart first and second surface portions defining a notch there between which is wider at its top than at its bottom and which extends outward from the axis. The second surface portion is outside curved, and a first edge of the cloth seal is positioned in the bottom of the notch. A second tubular end portion, such as a first stage nozzle, is located near, spaced apart from, and coaxially aligned with, the first tubular end portion. The second tubular end portion has a smooth third surface portion which surrounds at least a portion of the first tubular end portion and which is contacted by the cloth seal. 7 figs.

  6. Flexible swivel connection

    DOEpatents

    Hoh, J.C.

    1985-02-19

    A flexible swivel boot connector for connecting a first boot shield section to a second boot shield section, both first and second boot sections having openings therethrough, the second boot section having at least two adjacent accordian folds at the end having the opening, the second boot section being positioned through the opening of the first boot section such that a first of the accordian folds is within the first boot section and a second of the accordian folds is outside of the first boot, includes first and second annular discs, the first disc being positioned within and across the first accordian fold, the second disc being positioned within and across the second accordian fold, such that the first boot section is moveably and rigidly connected between the first and second accordian folds of the second boot section.

  7. Conformational flexibility of aspartame.

    PubMed

    Toniolo, Claudio; Temussi, Pierandrea

    2016-05-01

    L-Aspartyl-L-phenylalanine methyl ester, better known as aspartame, is not only one of the most used artificial sweeteners, but also a very interesting molecule with respect to the correlation between molecular structure and taste. The extreme conformational flexibility of this dipeptide posed a huge difficulty when researchers tried to use it as a lead compound to design new sweeteners. In particular, it was difficult to take advantage of its molecular model as a mold to infer the shape of the, then unknown, active site of the sweet taste receptor. Here, we follow the story of the 3D structural aspects of aspartame from early conformational studies to recent docking into homology models of the receptor. © 2016 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 106: 376-384, 2016. PMID:27038223

  8. Can Flexible Non-Linear Modeling Tell Us Anything New about Educational Productivity?

    ERIC Educational Resources Information Center

    Baker, Bruce D.

    2001-01-01

    Explores whether flexible nonlinear models (including neural networks and genetic algorithms) can reveal otherwise unexpected patterns of relationship in typical school-productivity data. Applying three types of algorithms alongside regression modeling to school-level data in 183 elementary schools proves the hypothesis and reveals new directions…

  9. Online Planning Algorithm

    NASA Technical Reports Server (NTRS)

    Rabideau, Gregg R.; Chien, Steve A.

    2010-01-01

    AVA v2 software selects goals for execution from a set of goals that oversubscribe shared resources. The term goal refers to a science or engineering request to execute a possibly complex command sequence, such as image targets or ground-station downlinks. Developed as an extension to the Virtual Machine Language (VML) execution system, the software enables onboard and remote goal triggering through the use of an embedded, dynamic goal set that can oversubscribe resources. From the set of conflicting goals, a subset must be chosen that maximizes a given quality metric, which in this case is strict priority selection. A goal can never be pre-empted by a lower priority goal, and high-level goals can be added, removed, or updated at any time, and the "best" goals will be selected for execution. The software addresses the issue of re-planning that must be performed in a short time frame by the embedded system where computational resources are constrained. In particular, the algorithm addresses problems with well-defined goal requests without temporal flexibility that oversubscribes available resources. By using a fast, incremental algorithm, goal selection can be postponed in a "just-in-time" fashion allowing requests to be changed or added at the last minute. Thereby enabling shorter response times and greater autonomy for the system under control.

  10. Telerobotic operation of structurally flexible, long-reach manipulators

    SciTech Connect

    Kwon, D.S.; Hwang, D.H.; Babcock, S.M.

    1994-09-01

    As a part of the Department of Energy`s Environmental Restoration and Waste Management Program, long-reach manipulators are being considered for the retrieval of waste from large storage tanks. Long-reach manipulators may have characteristics significantly different from those of typical industrial robots because of the flexibility of long links needed to cover the large workspace. To avoid structural vibrations during operation, control algorithms employing various types of shaping filters were investigated. A new approach that uses embedded simulation was developed and compared with others. In the new approach, generation of joint trajectories considering link flexibility was also investigated.

  11. A spectrum-scan routing scheme in flexible optical networks

    NASA Astrophysics Data System (ADS)

    Liu, Yang; Hua, Nan; Wan, Xin; Zheng, Xiaoping; Liu, Zhigang

    2011-12-01

    The routing and spectrum assignment (RSA) is one of the key problems in flexible optical networks. When in a gridless fashion, the shortest-path RSA algorithms have exponential computational complexity, and are thus not suitable to be employed in real networks. On the other hand, today most optical components cannot support fully gridless tunability, which also limits the application of gridless RSA schemes. In this paper, we propose a novel grid-based spectrum-scan routing (SSR) scheme in flexible optical networks. The SSR scheme achieves optimal routing with a polynomial computational complexity. Compared with other RSA schemes, SSR has shorter computation time, lower blocking probability, and higher resource utilization.

  12. Mechanically flexible organic electroluminescent device with directional light emission

    DOEpatents

    Duggal, Anil Raj; Shiang, Joseph John; Schaepkens, Marc

    2005-05-10

    A mechanically flexible and environmentally stable organic electroluminescent ("EL") device with directional light emission comprises an organic EL member disposed on a flexible substrate, a surface of which is coated with a multilayer barrier coating which includes at least one sublayer of a substantially transparent organic polymer and at least one sublayer of a substantially transparent inorganic material. The device includes a reflective metal layer disposed on the organic EL member opposite to the substrate. The reflective metal layer provides an increased external quantum efficiency of the device. The reflective metal layer and the multilayer barrier coating form a seal around the organic EL member to reduce the degradation of the device due to environmental elements.

  13. PeaksDB: New Software for Substantially Improved Peptide Identification from Orbitrap ETD Mass Spectrometry

    PubMed Central

    Zhang, J.; Xin, L.; Shan, B.; Chen, W.; Ma, B.

    2011-01-01

    Objective: To substantially improve the peptide identification sensitivity and accuracy from the Orbitrap ETD data with computational methods. Method: The algorithm takes full advantage of the characteristics of the Orbitrap ETD data, including: (1) high mass resolution of the precursor ions, and (2) the distributions of different fragment ion types in the MS/MS scans. For the first characteristic, a pre-search step is conducted to determine the precursor mass error distribution. This does not only make the precursor mass more accurate by a software recalibration, but also allows the use of the mass error as an important feature in the peptide-spectrum matching score function. For the second characteristic, the frequencies of different fragment ion types at different precursor charge states are statistically learned, and used in the score calculation. Moreover, the precursor-related ions in the MS/MS spectra are removed. Additionally, the score function makes use of the similarity between a database peptide and the de novo sequencing result. Result: PeaksDB was compared against three other search engines: MSGF-DB, Mascot, and ZCore. The same shuffled decoy database was appended to the target database and searched together to estimate the false discovery rate (FDR) of each individual engine. The same search parameters were used for all engines except that MSGFDB does not support variable PTMs. If no variable PTM is allowed, the numbers of identified peptides of different engines at 1% FDR are: PeaksDB (2356) > MSGF-DB (2147) > Mascot (1459) > ZCore (1030). If a few common PTMs are allowed, the numbers change to PeaksDB (3501) > Mascot (2677) > MSGF-DB (2147) > ZCore(1125). Conclusion: PeaksDB substantially improved the sensitivity and accuracy of peptide identifications on Orbitrap ETD data. At 1% false discovery rate, PeaksDB identified 1.3 to 1.6 times as many peptides as Mascot 2.3.

  14. Rapid flexible docking using a stochastic rotamer library of ligands

    PubMed Central

    Ding, Feng; Yin, Shuangye; Dokholyan, Nikolay V.

    2010-01-01

    Existing flexible docking approaches model the ligand and receptor flexibility either separately or in a loosely-coupled manner, which captures the conformational changes inefficiently. Here, we propose a flexible docking approach, MedusaDock, which models both ligand and receptor flexibility simultaneously with sets of discrete rotamers. We develop an algorithm to build the ligand rotamer library “on-the-fly” during docking simulations. MedusaDock benchmarks demonstrate a rapid sampling efficiency and high prediction accuracy in both self-docking (to the co-crystallized state) and cross-docking (to a state co-crystallized with a different ligand), the latter of which mimics the virtual-screening procedure in computational drug discovery. We also perform a virtual-screening test of four flexible kinase targets including cyclin-dependent kinase 2, vascular endothelial growth factor receptor 2, HIV reverse transcriptase, and HIV protease. We find significant improvements of virtual-screening enrichments when compared to rigid-receptor methods. The predictive power of MedusaDock in cross-docking and preliminary virtual-screening benchmarks highlights the importance to model both ligand and receptor flexibility simultaneously in computational docking. PMID:20712341

  15. Motion Cueing Algorithm Development: Initial Investigation and Redesign of the Algorithms

    NASA Technical Reports Server (NTRS)

    Telban, Robert J.; Wu, Weimin; Cardullo, Frank M.; Houck, Jacob A. (Technical Monitor)

    2000-01-01

    In this project four motion cueing algorithms were initially investigated. The classical algorithm generated results with large distortion and delay and low magnitude. The NASA adaptive algorithm proved to be well tuned with satisfactory performance, while the UTIAS adaptive algorithm produced less desirable results. Modifications were made to the adaptive algorithms to reduce the magnitude of undesirable spikes. The optimal algorithm was found to have the potential for improved performance with further redesign. The center of simulator rotation was redefined. More terms were added to the cost function to enable more tuning flexibility. A new design approach using a Fortran/Matlab/Simulink setup was employed. A new semicircular canals model was incorporated in the algorithm. With these changes results show the optimal algorithm has some advantages over the NASA adaptive algorithm. Two general problems observed in the initial investigation required solutions. A nonlinear gain algorithm was developed that scales the aircraft inputs by a third-order polynomial, maximizing the motion cues while remaining within the operational limits of the motion system. A braking algorithm was developed to bring the simulator to a full stop at its motion limit and later release the brake to follow the cueing algorithm output.

  16. Compact Active Vibration Control System for a Flexible Panel

    NASA Technical Reports Server (NTRS)

    Schiller, Noah H. (Inventor); Cabell, Randolph H. (Inventor); Perey, Daniel F. (Inventor)

    2014-01-01

    A diamond-shaped actuator for a flexible panel has an inter-digitated electrode (IDE) and a piezoelectric wafer portion positioned therebetween. The IDE and/or the wafer portion are diamond-shaped. Point sensors are positioned with respect to the actuator and measure vibration. The actuator generates and transmits a cancelling force to the panel in response to an output signal from a controller, which is calculated using a signal describing the vibration. A method for controlling vibration in a flexible panel includes connecting a diamond-shaped actuator to the flexible panel, and then connecting a point sensor to each actuator. Vibration is measured via the point sensor. The controller calculates a proportional output voltage signal from the measured vibration, and transmits the output signal to the actuator to substantially cancel the vibration in proximity to each actuator.

  17. Teacher Flexibility in Mathematical Discussion

    ERIC Educational Resources Information Center

    Leikin, Roza; Dinur, Sariga

    2007-01-01

    The significance of discussion in mathematics classes has been prominently debated in the research literature. Different studies have stressed the importance of teacher flexibility in orchestrating the discussion. We introduce an operational definition of teacher flexibility. In a case study with one secondary-school mathematics teacher, we…

  18. 26 CFR 1.6662-5T - Substantial and gross valuation misstatements under chapter 1 (temporary).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Substantial and gross valuation misstatements... Amounts, and Assessable Penalties § 1.6662-5T Substantial and gross valuation misstatements under chapter... related to section 482—(i) Substantial valuation misstatement. There is a substantial...

  19. Flexible phosphorene devices and circuits

    NASA Astrophysics Data System (ADS)

    Zhu, Weinan; Yogeesh, Maruthi N.; Akinwande, Deji

    2015-05-01

    Two-dimensional (2D) semiconductors with high carrier mobilities and sizeable bandgap are desirable for future high-speed and low power mechanically flexible nanoelectronics. In this work, we report encapsulated bottom-gated black phosphorus (BP) field-effect transistors (FETs) on flexible polyimide affording maximum carrier mobility of about 310cm2/V•s and current on/off ratio exceeding 103. Essential circuits of flexible electronic systems enabled by the device ambipolar functionality, high-mobility and current saturation are demonstrated in this work, including digital inverter, frequency doubler, and analog amplifiers featuring a voltage gain of ~8.7, which is the state-of-the-art value for flexible 2D semiconductor based amplifiers. In addition, we demonstrate the single FET based flexible BP amplitude-modulated (AM) demodulator, an active stage in radio receivers.

  20. [The flexibility of family medicine].

    PubMed

    Minguet, C; Aubrege, A; Aubart, M; Cornuz, J; di Patrizio, P; Du Boullay, D; Farghadani, H; Flammang, M; Haas, N; Kacenelenbogen, N; Kopp, M; Leners, J C; Levêque, M; Mbengue, M; Paur, H; Paur, I; Raphaël, F; Rausch, S; Shetgen, M; Stein R; Tabouring, P; Thomas, J M; Vignon, G

    2015-01-01

    We are a European academic group of family doctors and we propose a definition of flexibility in family medicine. A review of the literature shows that flexibility and complexity are emerging concepts in the field of family practice. The outcomes of a workshop at the WONCA-Europe congress in 2014 are discussed. The flexibility is a capability of the general practitioner to deal with complex clinical situations in a biomedical and societal changing world. Flexibility is framed by ethics. It could improve the quality of care, be useful against burnout and used in medical research. In conclusion, family medicine should adopt a specific definition of the flexibility describing its specificity, a useful and teachable capacity. PMID:26946851

  1. Conformational Flexibility in the Transmembrane Protein TSPO.

    PubMed

    Jaremko, Łukasz; Jaremko, Mariusz; Giller, Karin; Becker, Stefan; Zweckstetter, Markus

    2015-11-01

    The translocator protein (TSPO) is an integral membrane protein that interacts with a wide variety of endogenous ligands, such as cholesterol and porphyrins, and is also the target for several small molecules with substantial in vivo efficacy. When complexed with the TSPO-specific radioligand (R)-PK11195, TSPO folds into a rigid five-helix bundle. However, little is known about the structure and dynamics of TSPO in the absence of high-affinity ligands. By means of NMR spectroscopy, we show that TSPO exchanges between multiple conformations in the absence of (R)-PK11195. Extensive motions on time scales from pico- to microseconds occur all along the primary sequence of the protein, leading to a loss of stable tertiary interactions and local unfolding of the helical structure in the vicinity of the ligand-binding site. The flexible nature of TSPO highlights the importance of conformational plasticity in integral membrane proteins. PMID:26394723

  2. Conformational flexibility of mephenesin.

    PubMed

    Écija, Patricia; Evangelisti, Luca; Vallejo, Montserrat; Basterretxea, Francisco J; Lesarri, Alberto; Castaño, Fernando; Caminati, Walther; Cocinero, Emilio J

    2014-05-22

    The mephenesin molecule (3-(2-methylphenoxy)propane-1,2-diol) serves as a test bank to explore several structural and dynamical issues, such as conformational flexibility, the orientation of the carbon linear chain relative to the benzene plane, or the effect of substituent position on the rotational barrier of a methyl group. The molecule has been studied by rotational spectroscopy in the 4-18 GHz frequency range by Fourier-transform methods in a supersonic expansion. The experiment has been backed by a previous conformational search plus optimization of the lowest energy structures by ab initio and density functional quantum calculations. The three lowest-lying conformers that can interconvert to each other by simple bond rotations have been detected in the jet. Rotational parameters for all structures have been obtained, and methyl torsional barriers have been determined for the two lowest-lying rotamers. The lowest-lying structure of mephenesin is highly planar, with all carbon atoms lying nearly in the benzene ring plane, and is stabilized by the formation of cooperative intramolecular hydrogen bonding. An estimation of the relative abundance of the detected conformers indicates that the energetically most stable conformer will have an abundance near 80% at temperatures relevant for biological activity. PMID:24754523

  3. Transonic Wing Shape Optimization Using a Genetic Algorithm

    NASA Technical Reports Server (NTRS)

    Holst, Terry L.; Pulliam, Thomas H.; Kwak, Dochan (Technical Monitor)

    2002-01-01

    A method for aerodynamic shape optimization based on a genetic algorithm approach is demonstrated. The algorithm is coupled with a transonic full potential flow solver and is used to optimize the flow about transonic wings including multi-objective solutions that lead to the generation of pareto fronts. The results indicate that the genetic algorithm is easy to implement, flexible in application and extremely reliable.

  4. Flexible solid-state photoelectrochromic windows

    SciTech Connect

    Pichot, F.; Ferrere, S.; Pitts, R.J.; Gregg, B.A.

    1999-11-01

    Photoelectrochromic smart window technology is extended to include the use of flexible substrates and solid-state electrolytes. This should facilitate their application as retrofit modifications of office windows, where, by blocking incoming solar irradiation, they could substantially lower air-conditioning costs. These devices are based on a dye-sensitized TiO{sub 2} electrode coupled with a 500 nm thick WO{sub 3} electrochromic counter electrode, separated by a cross-linked polymer electrolyte containing LiI. A novel method for preparing conducting nanoporous TiO{sub 2} films is described that allows for the construction of these devices on flexible organic substrates. Colloidal solutions of TiO{sub 2} free of surfactants were spin-coated onto indium-tin oxide coated polyester substrates, resulting in highly transparent films ranging from 100 nm to 1 {micro}m in thickness. Upon annealing at 100 C, these films were strongly adherent and displayed excellent photoconductivity as shown by their current-voltage characteristics. The devices typically transmit 75% of visible light in the bleached state. After a few minutes of exposure to white light (75 mW/cm{sup 2}), the windows turn dark blue, transmitting only 30% of visible light. They spontaneously bleach back to their initial noncolored state upon removal of the light source.

  5. Identification of uncertain structural parameters in flexible boosters

    NASA Astrophysics Data System (ADS)

    Sawai, Shujiro; Kawaguchi, Jun'ichiro; Matsuo, Hiroki

    A novel algorithm for identification of unknown structural parameters in flexible boosters is presented here. In this method, first of all coefficient matrices in recursive form are estimated based on sensor outputs, which is followed by identifying structural parameters utilizing matrix relations between those and system description form. This algorithm is relatively robust and promising, since neither modal coordinates nor state reconstruction is required, in which tremendous amount of efforts have been to be concentrated to. Numerical discussion here was carried out and it demonstrated its practical effectiveness.

  6. Adaptive-Control Experiments On A Large Flexible Structure

    NASA Technical Reports Server (NTRS)

    Ih, Che-Hang C.; Bayard, David S.; Wang, Shyh J.; Eldred, Daniel B.

    1990-01-01

    Antennalike flexible structure built for research in advanced technology including suppression of vibrations and control of initial deflections. Structure instrumented with sensors and actuators connected to digital electronic control system, programmed with control algorithms to be tested. Particular attention in this research focused on direct model-reference adaptive-control algorithm based on command generator tracker theory. Built to exhibit multiple vibrational modes, low modal frequencies, and low structural damping. Made three-dimensional so complicated interactions among components of structure and control system investigated.

  7. Flexible Transmission in the Smart Grid

    NASA Astrophysics Data System (ADS)

    Hedman, Kory Walter

    There is currently a national push to create a smarter electric grid; introducing new technologies that will create a more controllable and flexible grid is part of the smart grid concept and integral to its success. The full control of transmission assets are not currently built into electric energy dispatch optimization models. Optimal transmission switching is a straightforward way to leverage grid controllability: to make better use of the existing system and meet growing demand with existing infrastructure. Previous research has shown that transmission switching as a corrective mechanism can help relieve line overloading, voltage violations, etc. However, there has been limited focus on the use of transmission switching as a means to improve the economic efficiency of the network by incorporating the control of transmission assets into the overall economic dispatch problem. This research discusses the ways that the modeling of flexible transmission assets can benefit the multi-trillion dollar electric industry. It presents and analyzes novel formulations by which the operator can incorporate this flexibility into the economic dispatch formulation. This research focuses on modeling transmission assets so that they can be temporarily taken out of service, i.e., by opening breakers, or kept in service, i.e., by keeping the breakers closed. By incorporating this control into the network optimization problem, this provides the ability for the operator to consider the state of a transmission line as a decision variable instead of treating it as a static asset, which is the current practice today. The possible benefits demonstrated from this research indicate that the benefits to society are substantial. On the contrary, the benefits to individual market participants are uncertain; some will benefit and other will not. Consequently, this research also analyzes the impacts that optimal transmission switching may have on market participants as well as the policy

  8. The dynamics and control of large flexible space structures

    NASA Technical Reports Server (NTRS)

    Bainum, P. M.; Kumar, V. K.; Krishna, R.; Reddy, A. S. S. R.; Diarra, C. M.

    1983-01-01

    Large, flexible orbiting systems proposed for possible use in communications, electronic orbital based mail systems, and solar energy collection are discussed. The size and low weight to area ratio of such systems indicate that system flexibility is now the main consideration in the dynamics and control problem. For such large, flexible systems, both orientation and surface shape control will often be required. A conceptual development plan of a system software capability for use in analysis of the dynamics and control of large space structures technology (LSST) systems is discussed. This concept can be subdivided into four different stages: (1) system dynamics; (2) structural dynamics; (3) application of control algorithms; and (4) simulation of environmental disturbances. Modeling the system dynamics of such systems in orbit is the most fundamental component. Solar radiation pressure effects and orbital and gravity gradient effects are discussed.

  9. Robustness of Flexible Systems With Component-Level Uncertainties

    NASA Technical Reports Server (NTRS)

    Maghami, Peiman G.

    2000-01-01

    Robustness of flexible systems in the presence of model uncertainties at the component level is considered. Specifically, an approach for formulating robustness of flexible systems in the presence of frequency and damping uncertainties at the component level is presented. The synthesis of the components is based on a modifications of a controls-based algorithm for component mode synthesis. The formulation deals first with robustness of synthesized flexible systems. It is then extended to deal with global (non-synthesized ) dynamic models with component-level uncertainties by projecting uncertainties from component levels to system level. A numerical example involving a two-dimensional simulated docking problem is worked out to demonstrate the feasibility of the proposed approach.

  10. Neural optimal control of flexible spacecraft slew maneuver

    NASA Astrophysics Data System (ADS)

    Nayeri, M. Reza Dehghan; Alasty, Aria; Daneshjou, Kamran

    2004-11-01

    This paper deals with the problem of optimal large-angle single-axis maneuvers of a flexible spacecraft with simultaneous vibration suppression of elastic modes. A spacecraft model with a cylindrical hub and one flexible appendage and tip mass is considered. Gravity gradient torque is considered as a disturbance torque. Multilayer perceptron neural networks are used to design a Neural Optimal Controller (NOC) for this multivariable non-linear maneuver. For NOC training, an off-line training procedure based on backpropagation through time algorithm is developed to minimize the general quadratic cost function in forward and backward pass stages. The proposed controller is also applicable to simultaneous multi-axis reorientation of a flexible spacecraft. Simulation results are presented to show that very fast reference pitch angle trajectory tracking and vibration suppression are accomplished.

  11. Swarming: flexible roaming plans.

    PubMed

    Partridge, Jonathan D; Harshey, Rasika M

    2013-03-01

    Movement over an agar surface via swarming motility is subject to formidable challenges not encountered during swimming. Bacteria display a great deal of flexibility in coping with these challenges, which include attracting water to the surface, overcoming frictional forces, and reducing surface tension. Bacteria that swarm on "hard" agar surfaces (robust swarmers) display a hyperflagellated and hyperelongated morphology. Bacteria requiring a "softer" agar surface (temperate swarmers) do not exhibit such a dramatic morphology. For polarly flagellated robust swarmers, there is good evidence that restriction of flagellar rotation somehow signals the induction of a large number of lateral flagella, but this scenario is apparently not relevant to temperate swarmers. Swarming bacteria can be further subdivided by their requirement for multiple stators (Mot proteins) or a stator-associated protein (FliL), secretion of essential polysaccharides, cell density-dependent gene regulation including surfactant synthesis, a functional chemotaxis signaling pathway, appropriate cyclic (c)-di-GMP levels, induction of virulence determinants, and various nutritional requirements such as iron limitation or nitrate availability. Swarming strategies are as diverse as the bacteria that utilize them. The strength of these numerous designs stems from the vantage point they offer for understanding mechanisms for effective colonization of surface niches, acquisition of pathogenic potential, and identification of environmental signals that regulate swarming. The signature swirling and streaming motion within a swarm is an interesting phenomenon in and of itself, an emergent behavior with properties similar to flocking behavior in diverse systems, including birds and fish, providing a convenient new avenue for modeling such behavior. PMID:23264580

  12. Swarming: Flexible Roaming Plans

    PubMed Central

    Partridge, Jonathan D.

    2013-01-01

    Movement over an agar surface via swarming motility is subject to formidable challenges not encountered during swimming. Bacteria display a great deal of flexibility in coping with these challenges, which include attracting water to the surface, overcoming frictional forces, and reducing surface tension. Bacteria that swarm on “hard” agar surfaces (robust swarmers) display a hyperflagellated and hyperelongated morphology. Bacteria requiring a “softer” agar surface (temperate swarmers) do not exhibit such a dramatic morphology. For polarly flagellated robust swarmers, there is good evidence that restriction of flagellar rotation somehow signals the induction of a large number of lateral flagella, but this scenario is apparently not relevant to temperate swarmers. Swarming bacteria can be further subdivided by their requirement for multiple stators (Mot proteins) or a stator-associated protein (FliL), secretion of essential polysaccharides, cell density-dependent gene regulation including surfactant synthesis, a functional chemotaxis signaling pathway, appropriate cyclic (c)-di-GMP levels, induction of virulence determinants, and various nutritional requirements such as iron limitation or nitrate availability. Swarming strategies are as diverse as the bacteria that utilize them. The strength of these numerous designs stems from the vantage point they offer for understanding mechanisms for effective colonization of surface niches, acquisition of pathogenic potential, and identification of environmental signals that regulate swarming. The signature swirling and streaming motion within a swarm is an interesting phenomenon in and of itself, an emergent behavior with properties similar to flocking behavior in diverse systems, including birds and fish, providing a convenient new avenue for modeling such behavior. PMID:23264580

  13. Electronic applications of flexible graphite

    NASA Astrophysics Data System (ADS)

    Luo, Xiangcheng; Chugh, Randy; Biller, Brian C.; Hoi, Yie Meng; Chung, D. D. L.

    2002-05-01

    Flexible graphite is effective for electronic applications, specifically electromagnetic interference (EMI) gasketing, resistive heating, thermoelectric-energy generation, and heat dissipation. It is comparable to or better than conductive-filled silicone materials for EMI gasketing. The shielding effectiveness reaches 125 dB. Flexible graphite as a heating element provides temperatures up to 980°C, response half-time down to 4 sec, and heat output at 60 sec up to 5600 J. The through-thickness, absolute thermoelectric power of flexible graphite is -2.6 µV/°C. Flexible graphite is effective as a thermal-interface material if the thickness is low (0.13 mm), the density is low (1.1 g/cm3), and the contact pressure is high (11.1 MPa). These applications make use of the flexibility and compliance of flexible graphite, in addition to its electronic and thermal behavior. Compliance is particularly important for the use of flexible graphite as interface materials, whether the interface is electrom agnetic, thermoelectric, or thermal.

  14. The joys and perils of flexible fitting.

    PubMed

    Volkmann, Niels

    2014-01-01

    While performing their functions, biological macromolecules often form large, dynamically changing macromolecular assemblies. Only a relatively small number of such assemblies have been accessible to the atomic-resolution techniques X-ray crystallography and NMR. Electron microscopy in conjunction with image reconstruction has become the preferred alternative for revealing the structures of such macromolecular complexes. However, for most assemblies the achievable resolution is too low to allow accurate atomic modeling directly from the data. Yet, useful models often can be obtained by fitting atomic models of individual components into a low-resolution reconstruction of the entire assembly. Several algorithms for achieving optimal fits in this context were developed recently, many allowing considerable degrees of flexibility to account for binding-induced conformational changes of the assembly components. This chapter describes the advantages and potential pitfalls of these methods and puts them into perspective with alternative approaches such as iterative modular fitting of rigid-body domains. PMID:24446360

  15. Precision pointing and control of flexible spacecraft

    NASA Technical Reports Server (NTRS)

    Bantell, M. H., Jr.

    1987-01-01

    The problem and long term objectives for the precision pointing and control of flexible spacecraft are given. The four basic objectives are stated in terms of two principle tasks. Under Task 1, robust low order controllers, improved structural modeling methods for control applications and identification methods for structural dynamics are being developed. Under Task 2, a lab test experiment for verification of control laws and system identification algorithms is being developed. For Task 1, work has focused on robust low order controller design and some initial considerations for structural modeling in control applications. For Task 2, work has focused on experiment design and fabrication, along with sensor selection and initial digital controller implementation. Conclusions are given.

  16. Random motion analysis of flexible satellite structures

    NASA Technical Reports Server (NTRS)

    Huang, T. C.; Das, A.

    1978-01-01

    A singular perturbation formulation is used to study the responses of a flexible satellite when random measurement errors can occur. The random variables, at different instants of time, are assumed to be uncorrelated. Procedures for obtaining maxima and minima are described, and a variation of the linear method is developed for the formal solution of the two-point boundary-value problems represented by the variational equations. Random and deterministic solutions for the structural position coordinates are studied, and an analytic algorithm for treating the force equation of motion is developed. Since the random system indicated by the variational equation will always be asymptotically unstable, any analysis of stability must be based on the deterministic system.

  17. Scenario aggregation for supply chain quantity-flexibility contract

    NASA Astrophysics Data System (ADS)

    Kim, Gitae; Wu, Chih-Hang

    2013-11-01

    In this research, we apply a scenario aggregation approach to solving the supply chain contract model formulated by two-stage stochastic programming problem. The supply chain contract can achieve the coordination between the buyer and the supplier. We formulate the stochastic programming model for a quantity-flexibility contract. The scenario aggregation method called the progressive hedging method is used to solve this problem. Experimental results show the convergence behaviour of the algorithm and the sensitivity of parameters.

  18. A new frame-based registration algorithm.

    PubMed

    Yan, C H; Whalen, R T; Beaupre, G S; Sumanaweera, T S; Yen, S Y; Napel, S

    1998-01-01

    This paper presents a new algorithm for frame registration. Our algorithm requires only that the frame be comprised of straight rods, as opposed to the N structures or an accurate frame model required by existing algorithms. The algorithm utilizes the full 3D information in the frame as well as a least squares weighting scheme to achieve highly accurate registration. We use simulated CT data to assess the accuracy of our algorithm. We compare the performance of the proposed algorithm to two commonly used algorithms. Simulation results show that the proposed algorithm is comparable to the best existing techniques with knowledge of the exact mathematical frame model. For CT data corrupted with an unknown in-plane rotation or translation, the proposed technique is also comparable to the best existing techniques. However, in situations where there is a discrepancy of more than 2 mm (0.7% of the frame dimension) between the frame and the mathematical model, the proposed technique is significantly better (p < or = 0.05) than the existing techniques. The proposed algorithm can be applied to any existing frame without modification. It provides better registration accuracy and is robust against model mis-match. It allows greater flexibility on the frame structure. Lastly, it reduces the frame construction cost as adherence to a concise model is not required. PMID:9472834

  19. A new frame-based registration algorithm

    NASA Technical Reports Server (NTRS)

    Yan, C. H.; Whalen, R. T.; Beaupre, G. S.; Sumanaweera, T. S.; Yen, S. Y.; Napel, S.

    1998-01-01

    This paper presents a new algorithm for frame registration. Our algorithm requires only that the frame be comprised of straight rods, as opposed to the N structures or an accurate frame model required by existing algorithms. The algorithm utilizes the full 3D information in the frame as well as a least squares weighting scheme to achieve highly accurate registration. We use simulated CT data to assess the accuracy of our algorithm. We compare the performance of the proposed algorithm to two commonly used algorithms. Simulation results show that the proposed algorithm is comparable to the best existing techniques with knowledge of the exact mathematical frame model. For CT data corrupted with an unknown in-plane rotation or translation, the proposed technique is also comparable to the best existing techniques. However, in situations where there is a discrepancy of more than 2 mm (0.7% of the frame dimension) between the frame and the mathematical model, the proposed technique is significantly better (p < or = 0.05) than the existing techniques. The proposed algorithm can be applied to any existing frame without modification. It provides better registration accuracy and is robust against model mis-match. It allows greater flexibility on the frame structure. Lastly, it reduces the frame construction cost as adherence to a concise model is not required.

  20. Automatic body flexibility classification using laser doppler flowmeter

    NASA Astrophysics Data System (ADS)

    Lien, I.-Chan; Li, Yung-Hui; Bau, Jian-Guo

    2015-10-01

    Body flexibility is an important indicator that can measure whether an individual is healthy or not. Traditionally, we need to prepare a protractor and the subject need to perform a pre-defined set of actions. The measurement takes place at the same time when the subject performs required action, which is clumsy and inconvenient. In this paper, we propose a statistical learning model using the technique of random forest. The proposed system can classify body flexibility based on LDF signals analyzed in the frequency domain. The reasons of using random forest are because of their efficiency (fast in classification), interpretable structures and their ability to filter out irrelevant features. In addition, using random forest can prevent the problem of over-fitting, and the output model will become more robust to noises. In our experiment, we use chirp Z-transform (CZT), to transform a LDF signal into its energy values in five frequency bands. Combining the power of the random forest algorithm and frequency band analysis methods, a maximum recognition rate of 66% is achieved. Compared to traditional flexibility measuring process, the proposed system shortens the long and tedious stages of measurement to a simple, fast and pre-defined activity set. The major contributions of our work include (1) a novel body flexibility classification scheme using non-invasive biomedical sensor; (2) a set of designed protocol which is easy to conduct and practice; (3) a high precision classification scheme which combines the power of spectrum analysis and machine learning algorithms.

  1. Flexible sensors for biomedical technology.

    PubMed

    Vilela, Diana; Romeo, Agostino; Sánchez, Samuel

    2016-02-01

    Flexible sensing devices have gained a great deal of attention among the scientific community in recent years. The application of flexible sensors spans over several fields, including medicine, industrial automation, robotics, security, and human-machine interfacing. In particular, non-invasive health-monitoring devices are expected to play a key role in the improvement of patient life and in reducing costs associated with clinical and biomedical diagnostic procedures. Here, we focus on recent advances achieved in flexible devices applied on the human skin for biomedical and healthcare purposes. PMID:26675174

  2. Guideline Implementation: Processing Flexible Endoscopes.

    PubMed

    Bashaw, Marie A

    2016-09-01

    The updated AORN "Guideline for processing flexible endoscopes" provides guidance to perioperative, endoscopy, and sterile processing personnel for processing all types of reusable flexible endoscopes and accessories in all procedural settings. This article focuses on key points of the guideline to help perioperative personnel safely and effectively process flexible endoscopes to prevent infection transmission. The key points address verification of manual cleaning, mechanical cleaning and processing, storage in a drying cabinet, determination of maximum storage time before reprocessing is needed, and considerations for implementing a microbiologic surveillance program. Perioperative RNs should review the complete guideline for additional information and for guidance when writing and updating policies and procedures. PMID:27568535

  3. Rolling-cuff flexible bellows

    DOEpatents

    Lambert, D.R.

    1982-09-27

    A flexible connector apparatus used to join two stiff non-deformable members, such as piping, is described. The apparatus is provided with one or more flexible sections or assemblies each utilizing a bellows of a rolling cuff type connected between two ridge members, with the bellows being supported by a back-up ring, such that only the curved end sections of the bellows are unsupported. Thus, the bellows can be considered as being of a tube-shaped configuration and thus have high pressure resistance. The components of the flexible apparatus are sealed or welded one to another such that it is fluid tight.

  4. High performance flexible heat pipes

    NASA Technical Reports Server (NTRS)

    Shaubach, R. M.; Gernert, N. J.

    1985-01-01

    A Phase I SBIR NASA program for developing and demonstrating high-performance flexible heat pipes for use in the thermal management of spacecraft is examined. The program combines several technologies such as flexible screen arteries and high-performance circumferential distribution wicks within an envelope which is flexible in the adiabatic heat transport zone. The first six months of work during which the Phase I contract goal were met, are described. Consideration is given to the heat-pipe performance requirements. A preliminary evaluation shows that the power requirement for Phase II of the program is 30.5 kilowatt meters at an operating temperature from 0 to 100 C.

  5. Air cushion vehicle conductive/semiconductive flexible skirt, and method

    NASA Astrophysics Data System (ADS)

    Cavenagh, Richard A.; Dyke, Raymond W.

    1990-03-01

    Discussed here is a method for dissipating static electrical energy from air cushion vehicles when operating more particularly in cold, low humidity environments, which method involves fabricating the skirt assembly from a flexible sheet material of at least semiconductive character, which will provide a suitable dissipating grounding pathway to discharge potential static electrical energy generated during the aforesaid operation. The method includes using a coated flexible fabric material having at least one of its opposite surfaces coated with an elastomeric abrasion-resistant material, and embedding a plurality of electrically conductive flexible strands at least partially within said flexible fabric material, or alternatively embedding electrically conductive particles or fibers in a generally uniformly manner throughout a forming of its elastomeric composition. The invention also is directed specifically to/on an air cushion vehicle skirt component comprised of electrically conductive composite flexible sheet material having sufficient conductive characteristics to provide a near constant dissipation grounding pathway from said vehicle for any substantial build up of generated static electrical energy, more particularly when the air cushion vehicle is operating in cold, low humidity environments.

  6. Flexible embedding of networks

    NASA Astrophysics Data System (ADS)

    Fernandez-Gracia, Juan; Buckee, Caroline; Onnela, Jukka-Pekka

    We introduce a model for embedding one network into another, focusing on the case where network A is much bigger than network B. Nodes from network A are assigned to the nodes in network B using an algorithm where we control the extent of localization of node placement in network B using a single parameter. Starting from an unassigned node in network A, called the source node, we first map this node to a randomly chosen node in network B, called the target node. We then assign the neighbors of the source node to the neighborhood of the target node using a random walk based approach. To assign each neighbor of the source node to one of the nodes in network B, we perform a random walk starting from the target node with stopping probability α. We repeat this process until all nodes in network A have been mapped to the nodes of network B. The simplicity of the model allows us to calculate key quantities of interest in closed form. By varying the parameter α, we are able to produce embeddings from very local (α = 1) to very global (α --> 0). We show how our calculations fit the simulated results, and we apply the model to study how social networks are embedded in geography and how the neurons of C. Elegans are embedded in the surrounding volume.

  7. Flexible Learning in a Digital World.

    ERIC Educational Resources Information Center

    Collis, Betty; Moonen, Jef

    2002-01-01

    Defines flexible learning and describes components of flexible learning in higher education, including technology, pedagogy or instructional approach, implementation strategies, and institutional framework. Considers factors constraining learning flexibility; changing student characteristics; and the need for lifelong learning, particularly in the…

  8. Fourier Lucas-Kanade algorithm.

    PubMed

    Lucey, Simon; Navarathna, Rajitha; Ashraf, Ahmed Bilal; Sridharan, Sridha

    2013-06-01

    In this paper, we propose a framework for both gradient descent image and object alignment in the Fourier domain. Our method centers upon the classical Lucas & Kanade (LK) algorithm where we represent the source and template/model in the complex 2D Fourier domain rather than in the spatial 2D domain. We refer to our approach as the Fourier LK (FLK) algorithm. The FLK formulation is advantageous when one preprocesses the source image and template/model with a bank of filters (e.g., oriented edges, Gabor, etc.) as 1) it can handle substantial illumination variations, 2) the inefficient preprocessing filter bank step can be subsumed within the FLK algorithm as a sparse diagonal weighting matrix, 3) unlike traditional LK, the computational cost is invariant to the number of filters and as a result is far more efficient, and 4) this approach can be extended to the Inverse Compositional (IC) form of the LK algorithm where nearly all steps (including Fourier transform and filter bank preprocessing) can be precomputed, leading to an extremely efficient and robust approach to gradient descent image matching. Further, these computational savings translate to nonrigid object alignment tasks that are considered extensions of the LK algorithm, such as those found in Active Appearance Models (AAMs). PMID:23599053

  9. Photocatalytic reactor with flexible supports

    DOEpatents

    Jacoby, William A.; Blake, Daniel M.

    1995-01-01

    Organic pollutants and bioaerosols in a gaseous stream are oxidized by exposure to light (e.g., UV light) in the presence of semiconductor catalyst particles or coatings supported on flexible strips suspended in the gaseous stream.

  10. Photocatalytic reactor with flexible supports

    DOEpatents

    Jacoby, W.A.; Blake, D.M.

    1995-09-12

    Organic pollutants and bioaerosols in a gaseous stream are oxidized by exposure to light (e.g., UV light) in the presence of semiconductor catalyst particles or coatings supported on flexible strips suspended in the gaseous stream. 3 figs.

  11. Ultra-Thin, Flexible Electronics

    NASA Technical Reports Server (NTRS)

    Holland, Brian; McPherson, Ryan; Zhang, Tan; Hou, Zhenwei; Dean, Robert; Johnson, R. Wayne; DelCastillo, Linda; Moussessian, Alina

    2008-01-01

    Thinned die can be used to realize ultra-thin flexible electronics for applications such as conformal and wearable electronics. Three techniques have been developed to achieve this goal using thinned die: die flip chip bonded onto flexible substrates, die laminated onto LCP films, and die embedded in polyimide. A key to achieving each of these techniques is the thinning of die to a thickness of 50 microns or thinner. Conventional CMP processing can be used to thin to 50 microns. At 50 microns, the active die become flexible and must be handled by temporarily bonding them to a holder die, for further processing. Once bonded face down to the holder die, the active die can be further thinned by DRIE etching the exposed backside. The thinned die can then been packaged in or on the flexible substrate.

  12. Flexible Transparent Electronic Gas Sensors.

    PubMed

    Wang, Ting; Guo, Yunlong; Wan, Pengbo; Zhang, Han; Chen, Xiaodong; Sun, Xiaoming

    2016-07-01

    Flexible and transparent electronic gas sensors capable of real-time, sensitive, and selective analysis at room-temperature, have gained immense popularity in recent years for their potential to be integrated into various smart wearable electronics and display devices. Here, recent advances in flexible transparent sensors constructed from semiconducting oxides, carbon materials, conducting polymers, and their nanocomposites are presented. The sensing material selection, sensor device construction, and sensing mechanism of flexible transparent sensors are discussed in detail. The critical challenges and future development associated with flexible and transparent electronic gas sensors are presented. Smart wearable gas sensors are believed to have great potential in environmental monitoring and noninvasive health monitoring based on disease biomarkers in exhaled gas. PMID:27276698

  13. Marine Technology: Diversity and Flexibility

    ERIC Educational Resources Information Center

    Buck, Dale R.

    1973-01-01

    Training for a specific field must reflect the diversity of that field and also remain flexible enough to accommodate fluctuations in the job market and the field, as marine technology illustrates. (Editor)

  14. Algorithms for optimal dyadic decision trees

    SciTech Connect

    Hush, Don; Porter, Reid

    2009-01-01

    A new algorithm for constructing optimal dyadic decision trees was recently introduced, analyzed, and shown to be very effective for low dimensional data sets. This paper enhances and extends this algorithm by: introducing an adaptive grid search for the regularization parameter that guarantees optimal solutions for all relevant trees sizes, revising the core tree-building algorithm so that its run time is substantially smaller for most regularization parameter values on the grid, and incorporating new data structures and data pre-processing steps that provide significant run time enhancement in practice.

  15. Complexity of the Quantum Adiabatic Algorithm

    NASA Technical Reports Server (NTRS)

    Hen, Itay

    2013-01-01

    The Quantum Adiabatic Algorithm (QAA) has been proposed as a mechanism for efficiently solving optimization problems on a quantum computer. Since adiabatic computation is analog in nature and does not require the design and use of quantum gates, it can be thought of as a simpler and perhaps more profound method for performing quantum computations that might also be easier to implement experimentally. While these features have generated substantial research in QAA, to date there is still a lack of solid evidence that the algorithm can outperform classical optimization algorithms.

  16. Flexible solar-array mechanism

    NASA Technical Reports Server (NTRS)

    Olson, M. C.

    1972-01-01

    One of the key elements of the flexible rolled-up solar array system is a mechanism to deploy, retract, and store the flexible solar-cell arrays. The selection of components, the design of the mechanism assembly, and the tests that were performed are discussed. During 6 months in orbit, all mission objectives were satisfied, and inflight performance has shown good correlation with preflight analyses and tests.

  17. Developmental constraints on behavioural flexibility

    PubMed Central

    Holekamp, Kay E.; Swanson, Eli M.; Van Meter, Page E.

    2013-01-01

    We suggest that variation in mammalian behavioural flexibility not accounted for by current socioecological models may be explained in part by developmental constraints. From our own work, we provide examples of constraints affecting variation in behavioural flexibility, not only among individuals, but also among species and higher taxonomic units. We first implicate organizational maternal effects of androgens in shaping individual differences in aggressive behaviour emitted by female spotted hyaenas throughout the lifespan. We then compare carnivores and primates with respect to their locomotor and craniofacial adaptations. We inquire whether antagonistic selection pressures on the skull might impose differential functional constraints on evolvability of skulls and brains in these two orders, thus ultimately affecting behavioural flexibility in each group. We suggest that, even when carnivores and primates would theoretically benefit from the same adaptations with respect to behavioural flexibility, carnivores may nevertheless exhibit less behavioural flexibility than primates because of constraints imposed by past adaptations in the morphology of the limbs and skull. Phylogenetic analysis consistent with this idea suggests greater evolutionary lability in relative brain size within families of primates than carnivores. Thus, consideration of developmental constraints may help elucidate variation in mammalian behavioural flexibility. PMID:23569298

  18. Flexible metal-organic frameworks.

    PubMed

    Schneemann, A; Bon, V; Schwedler, I; Senkovska, I; Kaskel, S; Fischer, R A

    2014-08-21

    Advances in flexible and functional metal-organic frameworks (MOFs), also called soft porous crystals, are reviewed by covering the literature of the five years period 2009-2013 with reference to the early pertinent work since the late 1990s. Flexible MOFs combine the crystalline order of the underlying coordination network with cooperative structural transformability. These materials can respond to physical and chemical stimuli of various kinds in a tunable fashion by molecular design, which does not exist for other known solid-state materials. Among the fascinating properties are so-called breathing and swelling phenomena as a function of host-guest interactions. Phase transitions are triggered by guest adsorption/desorption, photochemical, thermal, and mechanical stimuli. Other important flexible properties of MOFs, such as linker rotation and sub-net sliding, which are not necessarily accompanied by crystallographic phase transitions, are briefly mentioned as well. Emphasis is given on reviewing the recent progress in application of in situ characterization techniques and the results of theoretical approaches to characterize and understand the breathing mechanisms and phase transitions. The flexible MOF systems, which are discussed, are categorized by the type of metal-nodes involved and how their coordination chemistry with the linker molecules controls the framework dynamics. Aspects of tailoring the flexible and responsive properties by the mixed component solid-solution concept are included, and as well examples of possible applications of flexible metal-organic frameworks for separation, catalysis, sensing, and biomedicine. PMID:24875583

  19. Developmental constraints on behavioural flexibility.

    PubMed

    Holekamp, Kay E; Swanson, Eli M; Van Meter, Page E

    2013-05-19

    We suggest that variation in mammalian behavioural flexibility not accounted for by current socioecological models may be explained in part by developmental constraints. From our own work, we provide examples of constraints affecting variation in behavioural flexibility, not only among individuals, but also among species and higher taxonomic units. We first implicate organizational maternal effects of androgens in shaping individual differences in aggressive behaviour emitted by female spotted hyaenas throughout the lifespan. We then compare carnivores and primates with respect to their locomotor and craniofacial adaptations. We inquire whether antagonistic selection pressures on the skull might impose differential functional constraints on evolvability of skulls and brains in these two orders, thus ultimately affecting behavioural flexibility in each group. We suggest that, even when carnivores and primates would theoretically benefit from the same adaptations with respect to behavioural flexibility, carnivores may nevertheless exhibit less behavioural flexibility than primates because of constraints imposed by past adaptations in the morphology of the limbs and skull. Phylogenetic analysis consistent with this idea suggests greater evolutionary lability in relative brain size within families of primates than carnivores. Thus, consideration of developmental constraints may help elucidate variation in mammalian behavioural flexibility. PMID:23569298

  20. A Comparison of Two Approaches to Beta-Flexible Clustering.

    PubMed

    Belbin, L; Faith, D P; Milligan, G W

    1992-07-01

    We introduce a UPGMA based counterpart to the Lance and Williams (1966) p-flexible clustering strategy. This new method is compared with the original p-flexible technique based on WPGMA for a range of fl values from -0.8 to +0.1. Recovery of the known cluster structure from simulated data was evaluated using the Hubert and Arabie (1985) version of the Rand statistic. The algorithm used to generate the simulated clusters in the study included error-free data as well as three other error conditions. The simulated data also varied the number of clusters, the underlying dimensionality, and the density distribution of points to the clusters. Results showed that the flexible UPGMA gives the best recovery for all generated data configurations. Further, the flexible UPGMA method with a small negative β value performed better than the standard UPGMA method where β is set equal to zero. The flexible UPGMA strategy, employed with a narrow β range, is recommended based upon its ability to recover cluster structure over all error conditions. PMID:26789790

  1. Algorithmic chemistry

    SciTech Connect

    Fontana, W.

    1990-12-13

    In this paper complex adaptive systems are defined by a self- referential loop in which objects encode functions that act back on these objects. A model for this loop is presented. It uses a simple recursive formal language, derived from the lambda-calculus, to provide a semantics that maps character strings into functions that manipulate symbols on strings. The interaction between two functions, or algorithms, is defined naturally within the language through function composition, and results in the production of a new function. An iterated map acting on sets of functions and a corresponding graph representation are defined. Their properties are useful to discuss the behavior of a fixed size ensemble of randomly interacting functions. This function gas'', or Turning gas'', is studied under various conditions, and evolves cooperative interaction patterns of considerable intricacy. These patterns adapt under the influence of perturbations consisting in the addition of new random functions to the system. Different organizations emerge depending on the availability of self-replicators.

  2. 5 CFR 842.213 - Voluntary early retirement-substantial delayering, reorganization, reduction in force, transfer...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... delayering, reorganization, reduction in force, transfer of function, or other workforce restructuring. 842... early retirement-substantial delayering, reorganization, reduction in force, transfer of function, or... budgetary situation that will result in an excess of personnel because of a substantial...

  3. 5 CFR 831.114 - Voluntary early retirement-substantial delayering, reorganization, reduction in force, transfer...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... delayering, reorganization, reduction in force, transfer of function, or other workforce restructuring. 831...-substantial delayering, reorganization, reduction in force, transfer of function, or other workforce... situation that will result in an excess of personnel because of a substantial delayering,...

  4. 5 CFR 842.213 - Voluntary early retirement-substantial delayering, reorganization, reduction in force, transfer...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... delayering, reorganization, reduction in force, transfer of function, or other workforce restructuring. 842... early retirement-substantial delayering, reorganization, reduction in force, transfer of function, or... budgetary situation that will result in an excess of personnel because of a substantial...

  5. 5 CFR 842.213 - Voluntary early retirement-substantial delayering, reorganization, reduction in force, transfer...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... delayering, reorganization, reduction in force, transfer of function, or other workforce restructuring. 842... early retirement-substantial delayering, reorganization, reduction in force, transfer of function, or... budgetary situation that will result in an excess of personnel because of a substantial...

  6. 5 CFR 831.114 - Voluntary early retirement-substantial delayering, reorganization, reduction in force, transfer...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... delayering, reorganization, reduction in force, transfer of function, or other workforce restructuring. 831...-substantial delayering, reorganization, reduction in force, transfer of function, or other workforce... situation that will result in an excess of personnel because of a substantial delayering,...

  7. Flexible Language Constructs for Large Parallel Programs

    DOE PAGESBeta

    Rosing, Matt; Schnabel, Robert

    1994-01-01

    The goal of the research described in this article is to develop flexible language constructs for writing large data parallel numerical programs for distributed memory (multiple instruction multiple data [MIMD]) multiprocessors. Previously, several models have been developed to support synchronization and communication. Models for global synchronization include single instruction multiple data (SIMD), single program multiple data (SPMD), and sequential programs annotated with data distribution statements. The two primary models for communication include implicit communication based on shared memory and explicit communication based on messages. None of these models by themselves seem sufficient to permit the natural and efficient expression ofmore » the variety of algorithms that occur in large scientific computations. In this article, we give an overview of a new language that combines many of these programming models in a clean manner. This is done in a modular fashion such that different models can be combined to support large programs. Within a module, the selection of a model depends on the algorithm and its efficiency requirements. In this article, we give an overview of the language and discuss some of the critical implementation details.« less

  8. Flexible language constructs for large parallel programs

    NASA Technical Reports Server (NTRS)

    Rosing, Matthew; Schnabel, Robert

    1993-01-01

    The goal of the research described is to develop flexible language constructs for writing large data parallel numerical programs for distributed memory (MIMD) multiprocessors. Previously, several models have been developed to support synchronization and communication. Models for global synchronization include SIMD (Single Instruction Multiple Data), SPMD (Single Program Multiple Data), and sequential programs annotated with data distribution statements. The two primary models for communication include implicit communication based on shared memory and explicit communication based on messages. None of these models by themselves seem sufficient to permit the natural and efficient expression of the variety of algorithms that occur in large scientific computations. An overview of a new language that combines many of these programming models in a clean manner is given. This is done in a modular fashion such that different models can be combined to support large programs. Within a module, the selection of a model depends on the algorithm and its efficiency requirements. An overview of the language and discussion of some of the critical implementation details is given.

  9. Flow Interaction With Highly Flexible Structures

    NASA Astrophysics Data System (ADS)

    Shoele, Kourosh

    essential to high propulsion performance. We also note that this structural design is a recurring motif in nature. To understand flow-induced vibrations of deformable bluff objects, we study dynamics of a pressurized elastic ring within a uniform flow by using an immersed-boundary algorithm. The vibration of the flexible ring is decomposed into a pitching and flexible bending modes. Across the resonance region, nonlinear behavior of the ring is studied and the hydrodynamic loads are recorded. It is observed that within the resonance region, the lift force demonstrates a beating phenomenon reminiscent of findings from reduced models and low-degree-of-freedom systems.

  10. 24 CFR 115.201 - The two phases of substantial equivalency certification.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false The two phases of substantial... ENFORCEMENT AGENCIES Certification of Substantially Equivalent Agencies § 115.201 The two phases of.... The Department has developed a two-phase process of substantial equivalency certification....

  11. 26 CFR 1.671-1 - Grantors and others treated as substantial owners; scope.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Grantors and others treated as substantial... TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Grantors and Others Treated As Substantial Owners § 1.671-1 Grantors and others treated as substantial owners; scope. (a) Subpart E (section 671...

  12. 20 CFR 654.13 - Determination of areas of substantial unemployment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 3 2013-04-01 2013-04-01 false Determination of areas of substantial unemployment. 654.13 Section 654.13 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... 10582 § 654.13 Determination of areas of substantial unemployment. An area of substantial...

  13. 20 CFR 654.13 - Determination of areas of substantial unemployment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Determination of areas of substantial unemployment. 654.13 Section 654.13 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... 10582 § 654.13 Determination of areas of substantial unemployment. An area of substantial...

  14. 20 CFR 654.13 - Determination of areas of substantial unemployment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 3 2014-04-01 2014-04-01 false Determination of areas of substantial unemployment. 654.13 Section 654.13 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... 10582 § 654.13 Determination of areas of substantial unemployment. An area of substantial...

  15. 20 CFR 654.13 - Determination of areas of substantial unemployment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Determination of areas of substantial unemployment. 654.13 Section 654.13 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... 10582 § 654.13 Determination of areas of substantial unemployment. An area of substantial...

  16. 42 CFR 422.356 - Determining substantial financial risk and majority financial interest.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Determining substantial financial risk and majority... Provider-Sponsored Organizations § 422.356 Determining substantial financial risk and majority financial interest. (a) Determining substantial financial risk. The PSO must demonstrate to CMS's satisfaction...

  17. 20 CFR 654.13 - Determination of areas of substantial unemployment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Determination of areas of substantial unemployment. 654.13 Section 654.13 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... 10582 § 654.13 Determination of areas of substantial unemployment. An area of substantial...

  18. QPSO-Based Adaptive DNA Computing Algorithm

    PubMed Central

    Karakose, Mehmet; Cigdem, Ugur

    2013-01-01

    DNA (deoxyribonucleic acid) computing that is a new computation model based on DNA molecules for information storage has been increasingly used for optimization and data analysis in recent years. However, DNA computing algorithm has some limitations in terms of convergence speed, adaptability, and effectiveness. In this paper, a new approach for improvement of DNA computing is proposed. This new approach aims to perform DNA computing algorithm with adaptive parameters towards the desired goal using quantum-behaved particle swarm optimization (QPSO). Some contributions provided by the proposed QPSO based on adaptive DNA computing algorithm are as follows: (1) parameters of population size, crossover rate, maximum number of operations, enzyme and virus mutation rate, and fitness function of DNA computing algorithm are simultaneously tuned for adaptive process, (2) adaptive algorithm is performed using QPSO algorithm for goal-driven progress, faster operation, and flexibility in data, and (3) numerical realization of DNA computing algorithm with proposed approach is implemented in system identification. Two experiments with different systems were carried out to evaluate the performance of the proposed approach with comparative results. Experimental results obtained with Matlab and FPGA demonstrate ability to provide effective optimization, considerable convergence speed, and high accuracy according to DNA computing algorithm. PMID:23935409

  19. A flexible decision-aided maximum likelihood phase estimation in hybrid QPSK/OOK coherent optical WDM systems

    NASA Astrophysics Data System (ADS)

    Zhang, Yong; Wang, Yulong

    2016-04-01

    Although decision-aided (DA) maximum likelihood (ML) phase estimation (PE) algorithm has been investigated intensively, block length effect impacts system performance and leads to the increasing of hardware complexity. In this paper, a flexible DA-ML algorithm is proposed in hybrid QPSK/OOK coherent optical wavelength division multiplexed (WDM) systems. We present a general cross phase modulation (XPM) model based on Volterra series transfer function (VSTF) method to describe XPM effects induced by OOK channels at the end of dispersion management (DM) fiber links. Based on our model, the weighted factors obtained from maximum likelihood method are introduced to eliminate the block length effect. We derive the analytical expression of phase error variance for the performance prediction of coherent receiver with the flexible DA-ML algorithm. Bit error ratio (BER) performance is evaluated and compared through both theoretical derivation and Monte Carlo (MC) simulation. The results show that our flexible DA-ML algorithm has significant improvement in performance compared with the conventional DA-ML algorithm as block length is a fixed value. Compared with the conventional DA-ML with optimum block length, our flexible DA-ML can obtain better system performance. It means our flexible DA-ML algorithm is more effective for mitigating phase noise than conventional DA-ML algorithm.

  20. Improving load balance with flexibly assignable tasks

    SciTech Connect

    Pinar, Ali; Hendrickson, Bruce

    2003-09-09

    In many applications of parallel computing, distribution ofthe data unambiguously implies distribution of work among processors. Butthere are exceptions where some tasks can be assigned to one of severalprocessors without altering the total volume of communication. In thispaper, we study the problem of exploiting this flexibility in assignmentof tasks to improve load balance. We first model the problem in terms ofnetwork flow and use combinatorial techniques for its solution. Ourparametric search algorithms use maximum flow algorithms for probing on acandidate optimal solution value. We describe two algorithms to solve theassignment problem with \\logW_T and vbar P vbar probe calls, w here W_Tand vbar P vbar, respectively, denote the total workload and number ofproce ssors. We also define augmenting paths and cuts for this problem,and show that anyalgorithm based on augmenting paths can be used to findan optimal solution for the task assignment problem. We then consideracontinuous version of the problem, and formulate it as a linearlyconstrained optimization problem, i.e., \\min\\|Ax\\|_\\infty,\\; {\\rms.t.}\\;Bx=d. To avoid solving an intractable \\infty-norm optimization problem,we show that in this case minimizing the 2-norm is sufficient to minimizethe \\infty-norm, which reduces the problem to the well-studiedlinearly-constrained least squares problem. The continuous version of theproblem has the advantage of being easily amenable to parallelization.Our experiments with molecular dynamics and overlapped domaindecomposition applications proved the effectiveness of our methods withsignificant improvements in load balance. We also discuss how ourtechniques can be enhanced for heterogeneous systems.

  1. Mode estimation and adaptive feedforward control for stabilization of a flexible gun tube

    NASA Astrophysics Data System (ADS)

    Vandegrift, Mark W.; DiRenzo, Michael T.

    1998-07-01

    In this paper we describe an approach for designing a pointing and stabilization system for an unbalanced, flexible gun. Our approach is based upon classical control techniques as well as system identification and adaptive feedforward techniques. Adaptive algorithms identify the flexible modes of the system and estimate the dynamics unbalance. This information is used to update the control law in order to improve the stabilization accuracy of the system.

  2. Implementation of input command shaping to reduce vibration in flexible space structures

    NASA Technical Reports Server (NTRS)

    Chang, Kenneth W.; Seering, Warren P.; Rappole, B. Whitney

    1992-01-01

    Viewgraphs on implementation of input command shaping to reduce vibration in flexible space structures are presented. Goals of the research are to explore theory of input command shaping to find an efficient algorithm for flexible space structures; to characterize Middeck Active Control Experiment (MACE) test article; and to implement input shaper on the MACE structure and interpret results. Background on input shaping, simulation results, experimental results, and future work are included.

  3. Transform methods for precision continuum and control models of flexible space structures

    NASA Technical Reports Server (NTRS)

    Lupi, Victor D.; Turner, James D.; Chun, Hon M.

    1991-01-01

    An open loop optimal control algorithm is developed for general flexible structures, based on Laplace transform methods. A distributed parameter model of the structure is first presented, followed by a derivation of the optimal control algorithm. The control inputs are expressed in terms of their Fourier series expansions, so that a numerical solution can be easily obtained. The algorithm deals directly with the transcendental transfer functions from control inputs to outputs of interest, and structural deformation penalties, as well as penalties on control effort, are included in the formulation. The algorithm is applied to several structures of increasing complexity to show its generality.

  4. Force control for robotic manipulators with structurally flexible links

    NASA Astrophysics Data System (ADS)

    Latornell, Douglas John

    1992-01-01

    This thesis reports on the development of strategies for the control of contact forces exerted by a structurally flexible robotic manipulator on surfaces in its working environment. The controller is based on a multivariable, explicitly adaptive, long range predictive control algorithm. A static equilibrium bias term which is particularly applicable to the contact force control problem has been incorporated into the control algorithm cost function. A general formulation for the discrete time domain characteristic polynomial of the closed loop system has been derived and shown useful in tuning the controller. Kinematic and dynamic models of a robotic manipulator with structurally flexible links interacting with its working environment are derived. These models include inertia and damping effects in the contact dynamics in addition to the contact stiffness employed in most previous work. Linear analyses of the dynamic models for a variety of manipulator configurations reveal that the controlled variable, the contact force, is dominated by different open loop modes of the system depending on the effective stiffness of the contacting surfaces. This result has important implications for the selection of the controller parameters. The performance of the controller has been evaluated using computer simulation. A special purpose simulation program, TWOFLEX, which includes the dynamics models of the manipulator and the environment as well as the control algorithm was developed during the research. The configurations investigated using the simulation include a single flexible manipulator link, two link manipulators with both rigid and flexible links, and a two link prototype model of the Mobile Servicing System (MSS) manipulator for the proposed Space Station Freedom. The results show that the controller can be tuned to provide fast contact force step responses with minimal overshoot and zero steady-state error. The problem of maintaining control through the discontinuous

  5. Generation of Referring Expressions: Assessing the Incremental Algorithm

    ERIC Educational Resources Information Center

    van Deemter, Kees; Gatt, Albert; van der Sluis, Ielka; Power, Richard

    2012-01-01

    A substantial amount of recent work in natural language generation has focused on the generation of "one-shot" referring expressions whose only aim is to identify a target referent. Dale and Reiter's Incremental Algorithm (IA) is often thought to be the best algorithm for maximizing the similarity to referring expressions produced by people. We…

  6. Computational Controls Workstation: Algorithms and hardware

    NASA Technical Reports Server (NTRS)

    Venugopal, R.; Kumar, M.

    1993-01-01

    The Computational Controls Workstation provides an integrated environment for the modeling, simulation, and analysis of Space Station dynamics and control. Using highly efficient computational algorithms combined with a fast parallel processing architecture, the workstation makes real-time simulation of flexible body models of the Space Station possible. A consistent, user-friendly interface and state-of-the-art post-processing options are combined with powerful analysis tools and model databases to provide users with a complete environment for Space Station dynamics and control analysis. The software tools available include a solid modeler, graphical data entry tool, O(n) algorithm-based multi-flexible body simulation, and 2D/3D post-processors. This paper describes the architecture of the workstation while a companion paper describes performance and user perspectives.

  7. Flexible fibers in turbulent flows

    NASA Astrophysics Data System (ADS)

    Verhille, Gautier; Brouzet, Christophe; Le Gal, Patrice; Irphe Team

    2014-11-01

    We describe, for the first time, an experiment devoted to the study of the spatial conformation of a flexible fiber in a turbulent flow. We propose a model for the transition from rigid to flexible regimes as the intensity of turbulence is increased or the elastic energy of the fiber is decreased. This transition occurs for a fiber typical length which is observed experimentally and recovered by our analysis. We also demonstrate that the conformations of flexible fibers in a turbulent flow are analog to conformations of flexible polymers in a good solvent. This last result opens some new and creative ways to model flexible fiber distortions in turbulent flows while addressing fundamental problems in polymer dynamics. This work has been carried out in the framework of the Labex MEC Project (No. ANR-10-LABX-0092) and of the A*MIDEX Project (No. ANR-11-IDEX-0001-02), funded by the `Investissements d'Avenir' French Government program managed by the French National Research.

  8. An advanced dispatch simulator with advanced dispatch algorithm

    SciTech Connect

    Kafka, R.J. ); Fink, L.H. ); Balu, N.J. ); Crim, H.G. )

    1989-01-01

    This paper reports on an interactive automatic generation control (AGC) simulator. Improved and timely information regarding fossil fired plant performance is potentially useful in the economic dispatch of system generating units. Commonly used economic dispatch algorithms are not able to take full advantage of this information. The dispatch simulator was developed to test and compare economic dispatch algorithms which might be able to show improvement over standard economic dispatch algorithms if accurate unit information were available. This dispatch simulator offers substantial improvements over previously available simulators. In addition, it contains an advanced dispatch algorithm which shows control and performance advantages over traditional dispatch algorithms for both plants and electric systems.

  9. Innovations in Lattice QCD Algorithms

    SciTech Connect

    Konstantinos Orginos

    2006-06-25

    Lattice QCD calculations demand a substantial amount of computing power in order to achieve the high precision results needed to better understand the nature of strong interactions, assist experiment to discover new physics, and predict the behavior of a diverse set of physical systems ranging from the proton itself to astrophysical objects such as neutron stars. However, computer power alone is clearly not enough to tackle the calculations we need to be doing today. A steady stream of recent algorithmic developments has made an important impact on the kinds of calculations we can currently perform. In this talk I am reviewing these algorithms and their impact on the nature of lattice QCD calculations performed today.

  10. A comparison of heuristic search algorithms for molecular docking.

    PubMed

    Westhead, D R; Clark, D E; Murray, C W

    1997-05-01

    This paper describes the implementation and comparison of four heuristic search algorithms (genetic algorithm, evolutionary programming, simulated annealing and tabu search) and a random search procedure for flexible molecular docking. To our knowledge, this is the first application of the tabu search algorithm in this area. The algorithms are compared using a recently described fast molecular recognition potential function and a diverse set of five protein-ligand systems. Statistical analysis of the results indicates that overall the genetic algorithm performs best in terms of the median energy of the solutions located. However, tabu search shows a better performance in terms of locating solutions close to the crystallographic ligand conformation. These results suggest that a hybrid search algorithm may give superior results to any of the algorithms alone. PMID:9263849

  11. An Adaptive Unified Differential Evolution Algorithm for Global Optimization

    SciTech Connect

    Qiang, Ji; Mitchell, Chad

    2014-11-03

    In this paper, we propose a new adaptive unified differential evolution algorithm for single-objective global optimization. Instead of the multiple mutation strate- gies proposed in conventional differential evolution algorithms, this algorithm employs a single equation unifying multiple strategies into one expression. It has the virtue of mathematical simplicity and also provides users the flexibility for broader exploration of the space of mutation operators. By making all control parameters in the proposed algorithm self-adaptively evolve during the process of optimization, it frees the application users from the burden of choosing appro- priate control parameters and also improves the performance of the algorithm. In numerical tests using thirteen basic unimodal and multimodal functions, the proposed adaptive unified algorithm shows promising performance in compari- son to several conventional differential evolution algorithms.

  12. Analyses to improve operational flexibility

    SciTech Connect

    Trikouros, N.G.

    1986-01-01

    Operational flexibility is greatly enhanced if the technical bases for plant limits and design margins are fully understood, and the analyses necessary to evaluate the effect of plant modifications or changes in operating modes on these parameters can be performed as required. If a condition should arise that might jeopardize a plant limit or reduce operational flexibility, it would be necessary to understand the basis for the limit or the specific condition limiting operational flexibility and be capable of performing a reanalysis to either demonstrate that the limit will not be violated or to change the limit. This paper provides examples of GPU Nuclear efforts in this regard. Examples of Oyster Creek and Three Mile Island operating experiences are discussed.

  13. Flexible ultrasonic pipe inspection apparatus

    DOEpatents

    Jenkins, Charles F.; Howard, Boyd D.

    1998-01-01

    A flexible, modular ultrasonic pipe inspection apparatus, comprising a flexible, hollow shaft that carries a plurality of modules, including at least one rotatable ultrasonic transducer, a motor/gear unit, and a position/signal encoder. The modules are connected by flexible knuckle joints that allow each module of the apparatus to change its relative orientation with respect to a neighboring module, while the shaft protects electrical wiring from kinking or buckling while the apparatus moves around a tight corner. The apparatus is moved through a pipe by any suitable means, including a tether or drawstring attached to the nose or tail, differential hydraulic pressure, or a pipe pig. The rotational speed of the ultrasonic transducer and the forward velocity of the apparatus are coordinated so that the beam sweeps out the entire interior surface of the pipe, enabling the operator to accurately assess the condition of the pipe wall and determine whether or not leak-prone corrosion damage is present.

  14. Experimental demonstration of static shape control. [using flexible beam facility for large space structure development

    NASA Technical Reports Server (NTRS)

    Eldred, D.; Schaechter, D.

    1981-01-01

    Results of a microprocessor-controlled implementation of static shape control using a specially constructed flexible beam facility are presented. The discussion covers the development of shape control algorithms, adaptation of the algorithms for use with finite element models, construction of a flexible beam, characterization and calibration of the facility, development of a finite element model for the beam, and the development of computer hardware and software. It is shown that feedback control yields better results than open-loop control, and that the use of more than two sensors in the control loop has little effect on the system performance.

  15. Boundary flexibility method of component mode synthesis using static Ritz vectors

    NASA Technical Reports Server (NTRS)

    Abdallah, A. A.; Huckelbridge, A. A.

    1990-01-01

    A method of dynamic substructuring is presented which provides for the incorporation of a set of static Ritz vectors, referred to as boundary flexibility vectors, as a replacement and/or supplement to conventional eigenvectors in component mode synthesis. The suggested boundary flexibility Ritz vectors are generated by an extension of Wilson's load-dependent Ritz vector algorithm for transient dynamic analysis. The extended algorithm is not load-dependent, is applicable to both fixed-and free-interface components, and results in a general component mode synthesis model appropriate for any type of dynamic analysis.

  16. Stability of Bareiss algorithm

    NASA Astrophysics Data System (ADS)

    Bojanczyk, Adam W.; Brent, Richard P.; de Hoog, F. R.

    1991-12-01

    In this paper, we present a numerical stability analysis of Bareiss algorithm for solving a symmetric positive definite Toeplitz system of linear equations. We also compare Bareiss algorithm with Levinson algorithm and conclude that the former has superior numerical properties.

  17. Nursing shortages: let's be flexible.

    PubMed

    Sullivan, Christine; Reading, Sonya

    2002-10-01

    The following paper is a report outlining a significant work pattern change in an acute cardiac ward at a large Brisbane-based private hospital. The nursing staff expressed the desire for more flexible rostering and the opportunity to work 12-hour shifts. After agreement was reached between the hospital, the union and the Industrial Relations Board, guidelines were put in place and a Flexible Rostering System was proposed and trialed. An 80% consensus of staff was required both to proceed with the trial and to implement any permanent changes. Initially, the trial was conducted for three months and extended to six months. The shifts trialed were between four and 12 hours in length with varied starting and finishing times. The Flexible Rostering System was evaluated using feedback from staff surveys and the results of a staff vote. In addition, patient feedback, incident reports, financial and managerial evaluation of staff costs, hours per patient day utilised, sick leave, and the use of permanent staff for voluntary extra shifts were also monitored. The outcome of the trial was positive with over 80% of staff voting to implement the Flexible Rostering System permanently. A significant reduction in sick leave of 41% and improved retention of skilled registered nursing staff was noted. There was no increase in the number of incident reports or patient complaints. Both patients and nurses commented on the improved continuity of care. Salaries and wages were within budget. Staff surveys showed positive feedback such as increased morale, increased flexibility with rosters, decreased fatigue levels, improved patient assessment on night duty and an increase in number of days off. In conclusion, the Flexible Rostering System has been accepted as a positive change for staff and is cost effective for the hospital. In light of nursing shortages, the outcome of this trial cannot be ignored. PMID:12539924

  18. Computing Bounds on Resource Levels for Flexible Plans

    NASA Technical Reports Server (NTRS)

    Muscvettola, Nicola; Rijsman, David

    2009-01-01

    A new algorithm efficiently computes the tightest exact bound on the levels of resources induced by a flexible activity plan (see figure). Tightness of bounds is extremely important for computations involved in planning because tight bounds can save potentially exponential amounts of search (through early backtracking and detection of solutions), relative to looser bounds. The bound computed by the new algorithm, denoted the resource-level envelope, constitutes the measure of maximum and minimum consumption of resources at any time for all fixed-time schedules in the flexible plan. At each time, the envelope guarantees that there are two fixed-time instantiations one that produces the minimum level and one that produces the maximum level. Therefore, the resource-level envelope is the tightest possible resource-level bound for a flexible plan because any tighter bound would exclude the contribution of at least one fixed-time schedule. If the resource- level envelope can be computed efficiently, one could substitute looser bounds that are currently used in the inner cores of constraint-posting scheduling algorithms, with the potential for great improvements in performance. What is needed to reduce the cost of computation is an algorithm, the measure of complexity of which is no greater than a low-degree polynomial in N (where N is the number of activities). The new algorithm satisfies this need. In this algorithm, the computation of resource-level envelopes is based on a novel combination of (1) the theory of shortest paths in the temporal-constraint network for the flexible plan and (2) the theory of maximum flows for a flow network derived from the temporal and resource constraints. The measure of asymptotic complexity of the algorithm is O(N O(maxflow(N)), where O(x) denotes an amount of computing time or a number of arithmetic operations proportional to a number of the order of x and O(maxflow(N)) is the measure of complexity (and thus of cost) of a maximumflow

  19. [Flexibility competencies: emotional organization management].

    PubMed

    Caballero Muñoz, Domingo; Blanco Prieto, Antonio

    2007-11-01

    The aim of this article is to analyse the transferral of flexibility from contemporary organizations to workers. Through the approach of management by competencies, organizations try to develop in their workers behaviours that are related to efficient job performance. In order to appraise the importance of this approach, we used a critical-rational perspective to discuss the productivity demands that are characteristic of advanced industrial societies. The article shows how the link between workers' flexibility management and their emotional competencies affects their lives, which, like the organizations, should be versatile and adaptable to change. PMID:17959116

  20. Flexible Dermal Armor in Nature

    NASA Astrophysics Data System (ADS)

    Yang, Wen; Chen, Irene H.; Mckittrick, Joanna; Meyers, Marc A.

    2012-04-01

    Many animals possess dermal armor, which acts primarily as protection against predators. We illustrate this through examples from both our research and the literature: alligator, fish (alligator gar, arapaima, and Senegal bichir), armadillo, leatherback turtle, and a lizard, the Gila monster. The dermal armor in these animals is flexible and has a hierarchical structure with collagen fibers joining mineralized units (scales, tiles, or plates). This combination significantly increases the strength and flexibility in comparison with a simple monolithic mineral composite or rigid dermal armor. This dermal armor is being studied for future bioinspired armor applications providing increased mobility.

  1. Flexible graphene based microwave attenuators.

    PubMed

    Byun, Kisik; Ju Park, Yong; Ahn, Jong-Hyun; Min, Byung-Wook

    2015-02-01

    We demonstrate flexible 3 dB and 6 dB microwave attenuators using multilayer graphene grown by the chemical vapor deposition method. On the basis of the characterized results of multilayer graphene and graphene-Au ohmic contacts, the graphene attenuators are designed and measured. The flexible graphene-based attenuators have 3 dB and 6 dB attenuation with a return loss of less than -15 dB at higher than 5 GHz. The devices have shown durability in a bending cycling test of 100 times. The circuit model of the attenuator based on the characterized results matches the experimental results well. PMID:25590144

  2. Articulation and flexibility in the physical linkage between band 3 and the cytoskeleton in the human erythrocyte

    NASA Astrophysics Data System (ADS)

    Sawyer, William H.; Tilley, Leann M.

    1992-04-01

    The erythrocyte membrane with its underlying cytoskeleton undergoes gross deformation during passage of the cell through fine capillary networks in the circulation. The physical linkages between the cytoskeleton and the membrane must involve substantial internal flexibility or points of articulation within and between molecules in the system. We have used time-resolved phosphorescence spectroscopy to examine three aspects of this dynamic flexibility on the microsecond to millisecond time scale: (1) the rotational diffusion and internal flexibility of F-actin, (2) the intrinsic flexibility of spectrin in solution and when reconstituted to erythrocyte membranes, and (3) internal flexibility in the cytoplasmic domain of band three. The results show that the spectrin dimer displays substantial flexibility on the microsecond time scale: this flexibility is largely retained when spectrin is reassociated with the erythrocyte membrane. There is also evidence that the cytoplasmic domain of band three itself is flexible since the rotational correlation time for band three labeled through this domain (via a phosphorescently labeled monoclonal Fab) is significantly shorter than when the protein is labeled directly at the external face of its transmembrane domain. Short actin filaments possess limited torsional motion on the submicrosecond time scale and are unlikely to contribute to the flexibility of the cytoskeleton.

  3. Hyperspectral Imaging Using Flexible Endoscopy for Laryngeal Cancer Detection.

    PubMed

    Regeling, Bianca; Thies, Boris; Gerstner, Andreas O H; Westermann, Stephan; Müller, Nina A; Bendix, Jörg; Laffers, Wiebke

    2016-01-01

    Hyperspectral imaging (HSI) is increasingly gaining acceptance in the medical field. Up until now, HSI has been used in conjunction with rigid endoscopy to detect cancer in vivo. The logical next step is to pair HSI with flexible endoscopy, since it improves access to hard-to-reach areas. While the flexible endoscope's fiber optic cables provide the advantage of flexibility, they also introduce an interfering honeycomb-like pattern onto images. Due to the substantial impact this pattern has on locating cancerous tissue, it must be removed before the HS data can be further processed. Thereby, the loss of information is to minimize avoiding the suppression of small-area variations of pixel values. We have developed a system that uses flexible endoscopy to record HS cubes of the larynx and designed a special filtering technique to remove the honeycomb-like pattern with minimal loss of information. We have confirmed its feasibility by comparing it to conventional filtering techniques using an objective metric and by applying unsupervised and supervised classifications to raw and pre-processed HS cubes. Compared to conventional techniques, our method successfully removes the honeycomb-like pattern and considerably improves classification performance, while preserving image details. PMID:27529255

  4. Modelling the Shuttle Remote Manipulator System: Another flexible model

    NASA Technical Reports Server (NTRS)

    Barhorst, Alan A.

    1993-01-01

    High fidelity elastic system modeling algorithms are discussed. The particular system studied is the Space Shuttle Remote Manipulator System (RMS) undergoing full articulated motion. The model incorporates flexibility via a methodology the author has been developing. The technique is based in variational principles, so rigorous boundary condition generation and weak formulations for the associated partial differential equations are realized, yet the analyst need not integrate by parts. The methodology is formulated using vector-dyad notation with minimal use of tensor notation, therefore the technique is believed to be affable to practicing engineers. The objectives of this work are as follows: (1) determine the efficacy of the modeling method; and (2) determine if the method affords an analyst advantages in the overall modeling and simulation task. Generated out of necessity were Mathematica algorithms that quasi-automate the modeling procedure and simulation development. The project was divided into sections as follows: (1) model development of a simplified manipulator; (2) model development of the full-freedom RMS including a flexible movable base on a six degree of freedom orbiter (a rigid-body is attached to the manipulator end-effector); (3) simulation development for item 2; and (4) comparison to the currently used model of the flexible RMS in the Structures and Mechanics Division of NASA JSC. At the time of the writing of this report, items 3 and 4 above were not complete.

  5. Integrated Controls-Structures Design Methodology for Flexible Spacecraft

    NASA Technical Reports Server (NTRS)

    Maghami, P. G.; Joshi, S. M.; Price, D. B.

    1995-01-01

    This paper proposes an approach for the design of flexible spacecraft, wherein the structural design and the control system design are performed simultaneously. The integrated design problem is posed as an optimization problem in which both the structural parameters and the control system parameters constitute the design variables, which are used to optimize a common objective function, thereby resulting in an optimal overall design. The approach is demonstrated by application to the integrated design of a geostationary platform, and to a ground-based flexible structure experiment. The numerical results obtained indicate that the integrated design approach generally yields spacecraft designs that are substantially superior to the conventional approach, wherein the structural design and control design are performed sequentially.

  6. Evaluation of flexible pavement crack sealing methods used in Utah

    NASA Astrophysics Data System (ADS)

    Belangie, M. C.; Anderson, D. I.

    1981-01-01

    Criteria to improve the effectiveness of Utah's flexible pavements crack sealing practice were studied. Field measurements, in-depth interviews questionaires were used. Findings indicate that flexible pavement cracking is a significant problem in the Far West, Rocky Mountains, Great Lakes and New England. Choice of materials is effected by storage requirements and equipment available. Prepackaging of materials designed for crack sealing has resulted in improvements in control of mix and material properties. Low temperature and freeze thaw cycles significantly effect the amount of thermal cracking and the performance of crack sealant. Ductile sealants, such as Crumb rubber/asphalt cement mixes, in combination with routing appear to offer substantial gains in sealant life and performance.

  7. Technical considerations for flexible piping design in nuclear power plants

    SciTech Connect

    Lu, S.C.; Chou, C.K.

    1985-03-15

    The overall objective of this research project is to develop a technical basis for flexible piping designs which will improve piping reliability and minimize the use of pipe supports, snubbers, and pipe whip restraints. The current study was conducted to establish the necessary groundwork based on the piping reliability analysis. A confirmatory piping reliability assessment indicated that removing rigid supports and snubbers tends to either improve or affect very little the piping reliability. A couple of changes to be implemented in Regulatory Guide (RG) 1.61 and RG 1.122 aimed at more flexible piping design were investigated. It was concluded that these changes substantially reduce calculated piping responses and allows piping redesigns with significant reduction in number of supports and snubbers without violating ASME code requirements.

  8. Annealed Importance Sampling Reversible Jump MCMC algorithms

    SciTech Connect

    Karagiannis, Georgios; Andrieu, Christophe

    2013-03-20

    It will soon be 20 years since reversible jump Markov chain Monte Carlo (RJ-MCMC) algorithms have been proposed. They have significantly extended the scope of Markov chain Monte Carlo simulation methods, offering the promise to be able to routinely tackle transdimensional sampling problems, as encountered in Bayesian model selection problems for example, in a principled and flexible fashion. Their practical efficient implementation, however, still remains a challenge. A particular difficulty encountered in practice is in the choice of the dimension matching variables (both their nature and their distribution) and the reversible transformations which allow one to define the one-to-one mappings underpinning the design of these algorithms. Indeed, even seemingly sensible choices can lead to algorithms with very poor performance. The focus of this paper is the development and performance evaluation of a method, annealed importance sampling RJ-MCMC (aisRJ), which addresses this problem by mitigating the sensitivity of RJ-MCMC algorithms to the aforementioned poor design. As we shall see the algorithm can be understood as being an “exact approximation” of an idealized MCMC algorithm that would sample from the model probabilities directly in a model selection set-up. Such an idealized algorithm may have good theoretical convergence properties, but typically cannot be implemented, and our algorithms can approximate the performance of such idealized algorithms to an arbitrary degree while not introducing any bias for any degree of approximation. Our approach combines the dimension matching ideas of RJ-MCMC with annealed importance sampling and its Markov chain Monte Carlo implementation. We illustrate the performance of the algorithm with numerical simulations which indicate that, although the approach may at first appear computationally involved, it is in fact competitive.

  9. Can flexibility help you float?

    NASA Astrophysics Data System (ADS)

    Burton, L. J.; Bush, J. W. M.

    2012-10-01

    We consider the role of flexibility in the weight-bearing characteristics of bodies floating at an interface. Specifically, we develop a theoretical model for a two-dimensional thin floating plate that yields the maximum stable plate load and optimal stiffness for weight support. Plates small relative to the capillary length are primarily supported by surface tension, and their weight-bearing potential does not benefit from flexibility. Above a critical size comparable to the capillary length, flexibility assists interfacial flotation. For plates on the order of and larger than the capillary length, deflection from an initially flat shape increases the force resulting from hydrostatic pressure, allowing the plate to support a greater load. In this large plate limit, the shape that bears the most weight is a semicircle, which displaces the most fluid above the plate for a fixed plate length. Exact results for maximum weight-bearing plate shapes are compared to analytic approximations made in the limits of large and small plate sizes. The value of flexibility for floating to a number of biological organisms is discussed in light of our study.

  10. Flexible substrate for printed wiring

    NASA Technical Reports Server (NTRS)

    Asakura, M.; Yabe, K.; Tanaka, H.; Soda, A.

    1982-01-01

    A very flexible substrate for printed wiring is disclosed which is composed of a blend of phenoxy resin-polyisocyanate-brominated epoxy resin in which the equivalent ration of the functional groups is hydroxyl grouped: isocyanate group: epoxy group = 1:0.2 to 2:0.5 to 3. The product has outstanding solder resistance and is applied to metal without using adhesives.

  11. Flexibility in Language and Thought

    ERIC Educational Resources Information Center

    Srinivasan, Mahesh

    2011-01-01

    Many words can be used flexibly: a book can be physically heavy, but also have provocative content, a "chicken" might live in a coop, but could also be tasty to eat. What do the uses of "polysemous" words such as these reveal about the structure of language and thought? Paper 1 examined 4-year-old children's representations of polysemous words…

  12. Flexible Metal-Fabric Radiators

    NASA Technical Reports Server (NTRS)

    Cross, Cynthia; Nguyen, Hai D.; Ruemmele, Warren; Andish, Kambiz K.; McCalley, Sean

    2005-01-01

    Flexible metal-fabric radiators have been considered as alternative means of dissipating excess heat from spacecraft and space suits. The radiators also may be useful in such special terrestrial applications as rejecting heat from space-suit-like protective suits worn in hot work environments. In addition to flexibility and consequent ease of deployment and installation on objects of varying sizes and shapes, the main advantages of these radiators over conventional rigid radiators are that they weigh less and occupy less volume for a given amount of cooling capacity. A radiator of this type includes conventional stainless-steel tubes carrying a coolant fluid. The main radiating component consists of a fabric of interwoven aluminum-foil strips bonded to the tubes by use of a proprietary process. The strip/tube bonds are strong and highly thermally conductive. Coolant is fed to and from the tubes via flexible stainless-steel manifolds designed to accommodate flexing of, and minimize bending forces on, the fabric. The manifolds are sized to minimize pressure drops and distribute the flow of coolant evenly to all the tubes. The tubes and manifolds are configured in two independent flow loops for operational flexibility and protective redundancy.

  13. PNF and Other Flexibility Techniques.

    ERIC Educational Resources Information Center

    Cornelius, William L.

    Effective flexibility procedures are one of the essential tools by which excellence can be attained. Although stretching exercises provide obvious benefits, negative outcomes can result unless effective stretching procedures are incoroporated. Characteristics of effective stretching include warmup before stretching, stretch before and after…

  14. Trading Accountability for Greater Flexibility.

    ERIC Educational Resources Information Center

    Sanders, Ted

    1991-01-01

    Describes the plight of two risk-taking principals who drastically improved their schools' academic performance, only to be defeated by bureaucratic regulations and business-as-usual attitudes. Allowing schools greater flexibility in exchange for increased accountability will free talented teachers and principals to restructure schools and solve…

  15. Flexible Systems Invade the Factory.

    ERIC Educational Resources Information Center

    Kinnucan, Paul

    1983-01-01

    Flexible manufacturing systems (FMS) are systems that can be programed to alter their procedures to suit varying production requirements. Use of and trends related to these systems in the United States and foreign countries are discussed. A detailed diagram of a hypothetical FMS is provided. (JN)

  16. Flexible Work Schedules. ERIC Digest.

    ERIC Educational Resources Information Center

    Kerka, Sandra

    Flexible work schedules are one response to changes in the composition of the work force, new life-styles, and changes in work attitudes. Types of alternative work schedules are part-time and temporary employment, job sharing, and flextime. Part-time workers are a diverse group--women, the very young, and older near-retirees. Although part-time…

  17. Flexible Bistable Cholesteric Reflective Displays

    NASA Astrophysics Data System (ADS)

    Yang, Deng-Ke

    2006-03-01

    Cholesteric liquid crystals (ChLCs) exhibit two stable states at zero field condition-the reflecting planar state and the nonreflecting focal conic state. ChLCs are an excellent candidate for inexpensive and rugged electronic books and papers. This paper will review the display cell structure,materials and drive schemes for flexible bistable cholesteric (Ch) reflective displays.

  18. Flexible Schedules and Shift Work.

    ERIC Educational Resources Information Center

    Beers, Thomas M.

    2000-01-01

    Flexible work hours have gained prominence, as more than 25 million workers (27.6% of all full-time workers) can now vary their schedules. However, there has been little change since the mid-1980s in the proportion who work a shift other than a regular daytime shift. (JOW)

  19. Adaptive Control For Flexible Structures

    NASA Technical Reports Server (NTRS)

    Bayard, David S.; Ih, Che-Hang Charles; Wang, Shyh Jong

    1988-01-01

    Paper discusses ways to cope with measurement noise in adaptive control system for large, flexible structure in outer space. System generates control signals for torque and thrust actuators to turn all or parts of structure to desired orientations while suppressing torsional and other vibrations. Main result of paper is general theory for introduction of filters to suppress measurement noise while preserving stability.

  20. Student Involvement, Flexibility and Individualization.

    ERIC Educational Resources Information Center

    Ryberg, Donald

    1971-01-01

    Innovative curricular reforms in language instruction at an inner-city experimental high school are described in this article. The primary concern for flexibility in enrollment procedures, language offerings, planning of learning opportunities, and, in general, the total curriculum, is prompted by the recognition of individual differences and…

  1. Flexible Learning: A Luddite View

    ERIC Educational Resources Information Center

    Baggaley, Jon

    2011-01-01

    This article reflects on the flexible learning concept through the eyes of the 19th-century industrial activists known as the Luddites. During a period of economic uncertainty, the Luddite perspective provides a sensitive justification for a change-free educational environment, and for a backlash in favour of "inflexible learning" (IL). The…

  2. Exploring Quadrilaterals through Flexible Approaches

    ERIC Educational Resources Information Center

    Richardson, Kerri; Reynolds, Anne; Schwartz, Catherine S.

    2012-01-01

    The quadrilaterals problem is a particularly rich task, applicable to in-service teachers as well as to the students they teach. The ways in which students engage in this task, the strategies they use, and the mathematics that results align well with this "MT" Focus Issue on flexible mathematical thinking. The authors offer their observations of…

  3. States Seek Flexibility on Testing

    ERIC Educational Resources Information Center

    McNeil, Michele; Gewertz, Catherine

    2013-01-01

    With the debut of common assessments less than two years away, states and districts are worried about the accountability systems that hinge on those tests. A growing chorus of policy groups is urging more flexibility in how states evaluate teachers, label schools, and enforce other high-stakes consequences during what's likely to be a messy…

  4. Flexible separator for alkaline batteries

    NASA Technical Reports Server (NTRS)

    Sheibley, D. W.

    1977-01-01

    Device is fabricated from low-cost readily-available commercial-materials by automated methods utilizing conventional paper coating processes. Flexibility of unit prevents cracking and disintegration caused by electrode warpage and dendrite growth, major causes of early battery failure with present separators.

  5. Flexible ultrasonic pipe inspection apparatus

    DOEpatents

    Jenkins, C.F.; Howard, B.D.

    1994-01-01

    Pipe crawlers, pipe inspection {open_quotes}rabbits{close_quotes} and similar vehicles are widely used for inspecting the interior surfaces of piping systems, storage tanks and process vessels for damaged or flawed structural features. This paper describes the design of a flexible, modular ultrasonic pipe inspection apparatus.

  6. Robust on-off pulse control of flexible space vehicles

    NASA Technical Reports Server (NTRS)

    Wie, Bong; Sinha, Ravi

    1993-01-01

    The on-off reaction jet control system is often used for attitude and orbital maneuvering of various spacecraft. Future space vehicles such as the orbital transfer vehicles, orbital maneuvering vehicles, and space station will extensively use reaction jets for orbital maneuvering and attitude stabilization. The proposed robust fuel- and time-optimal control algorithm is used for a three-mass spacing model of flexible spacecraft. A fuel-efficient on-off control logic is developed for robust rest-to-rest maneuver of a flexible vehicle with minimum excitation of structural modes. The first part of this report is concerned with the problem of selecting a proper pair of jets for practical trade-offs among the maneuvering time, fuel consumption, structural mode excitation, and performance robustness. A time-optimal control problem subject to parameter robustness constraints is formulated and solved. The second part of this report deals with obtaining parameter insensitive fuel- and time- optimal control inputs by solving a constrained optimization problem subject to robustness constraints. It is shown that sensitivity to modeling errors can be significantly reduced by the proposed, robustified open-loop control approach. The final part of this report deals with sliding mode control design for uncertain flexible structures. The benchmark problem of a flexible structure is used as an example for the feedback sliding mode controller design with bounded control inputs and robustness to parameter variations is investigated.

  7. Direct model reference adaptive control of a flexible robotic manipulator

    NASA Technical Reports Server (NTRS)

    Meldrum, D. R.

    1985-01-01

    Quick, precise control of a flexible manipulator in a space environment is essential for future Space Station repair and satellite servicing. Numerous control algorithms have proven successful in controlling rigid manipulators wih colocated sensors and actuators; however, few have been tested on a flexible manipulator with noncolocated sensors and actuators. In this thesis, a model reference adaptive control (MRAC) scheme based on command generator tracker theory is designed for a flexible manipulator. Quicker, more precise tracking results are expected over nonadaptive control laws for this MRAC approach. Equations of motion in modal coordinates are derived for a single-link, flexible manipulator with an actuator at the pinned-end and a sensor at the free end. An MRAC is designed with the objective of controlling the torquing actuator so that the tip position follows a trajectory that is prescribed by the reference model. An appealing feature of this direct MRAC law is that it allows the reference model to have fewer states than the plant itself. Direct adaptive control also adjusts the controller parameters directly with knowledge of only the plant output and input signals.

  8. Modern control design for flexible wind turbines

    NASA Astrophysics Data System (ADS)

    Wright, Alan Duane

    Control can improve energy capture and reduce dynamic loads in wind turbines. In the 1970s and 1980s wind turbines used classical control designs to regulate power and speed. The methods used, however, were not always successful. These systems often had bandwidths large enough to destabilize low-damped flexible modes leading to high dynamic load fatigue failures. Modern turbines are larger, mounted on taller towers, and are more dynamically active than their predecessors. Control systems to regulate turbine power and maintain stable closed-loop behavior in the presence of turbulent wind inflow will be critical for these designs. New advanced control approaches and paradigms must account for low-damped flexible modes in order to reduce structural dynamic loading and achieve the 20--25 year operational life required of today's machines. This thesis applies modern state-space control design methods to a two-bladed teetering hub upwind machine located at the National Wind Technology Center. The design objective is to regulate turbine speed and enhance damping in several low-damped flexible modes of the turbine. Starting with simple control algorithms based on linear models, complexity is added incrementally until the desired performance is firmly established. The controls approach is based on the Disturbance Accommodating Control (DAC) method and provides accountability for wind-speed fluctuations. First, controls are designed using the single control input rotor collective pitch to stabilize the 1st drive-train torsion as well as the tower 1st fore-aft bending modes. Generator torque is then incorporated as an additional control input. This reduces some of the demand placed on the rotor collective pitch control system and enhances 1st drive train torsion mode damping. Individual blade pitch control is then used to attenuate wind disturbances having spatial variation over the rotor and effectively reduces blade flap deflections due to wind shear. Finally, results from

  9. 16 CFR 260.5 - Interpretation and substantiation of environmental marketing claims.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... substantiation of environmental marketing claims. Section 5 of the FTC Act makes unlawful deceptive acts and... deceptive or unsubstantiated environmental advertising claims. A current list of environmental...

  10. Development and Evaluation of an Order-N Formulation for Multi-Flexible Body Space Systems

    NASA Technical Reports Server (NTRS)

    Ghosh, Tushar K.; Quiocho, Leslie J.

    2013-01-01

    This paper presents development of a generic recursive Order-N algorithm for systems with rigid and flexible bodies, in tree or closed-loop topology, with N being the number of bodies of the system. Simulation results are presented for several test cases to verify and evaluate the performance of the code compared to an existing efficient dense mass matrix-based code. The comparison brought out situations where Order-N or mass matrix-based algorithms could be useful.

  11. Approach to recognition of flexible form for credit card expiration date recognition as example

    NASA Astrophysics Data System (ADS)

    Sheshkus, Alexander; Nikolaev, Dmitry P.; Ingacheva, Anastasia; Skoryukina, Natalya

    2015-12-01

    In this paper we consider a task of finding information fields within document with flexible form for credit card expiration date field as example. We discuss main difficulties and suggest possible solutions. In our case this task is to be solved on mobile devices therefore computational complexity has to be as low as possible. In this paper we provide results of the analysis of suggested algorithm. Error distribution of the recognition system shows that suggested algorithm solves the task with required accuracy.

  12. On the reliable and flexible solution of practical subset regression problems

    NASA Technical Reports Server (NTRS)

    Verhaegen, M.

    1987-01-01

    A new algorithm for solving subset regression problems is described. The algorithm performs a QR decomposition with a new column-pivoting strategy, which permits subset selection directly from the originally defined regression parameters. This, in combination with a number of extensions of the new technique, makes the method a very flexible tool for analyzing subset regression problems in which the parameters have a physical meaning.

  13. Domain decomposition approach to flexible multibody dynamics simulation

    NASA Astrophysics Data System (ADS)

    Kwak, JunYoung; Chun, TaeYoung; Shin, SangJoon; Bauchau, Olivier A.

    2014-01-01

    Finite element based formulations for flexible multibody systems are becoming increasingly popular and as the complexity of the configurations to be treated increases, so does the computational cost. It seems natural to investigate the applicability of parallel processing to this type of problems; domain decomposition techniques have been used extensively for this purpose. In this approach, the computational domain is divided into non-overlapping sub-domains, and the continuity of the displacement field across sub-domain boundaries is enforced via the Lagrange multiplier technique. In the finite element literature, this approach is presented as a mathematical algorithm that enables parallel processing. In this paper, the divided system is viewed as a flexible multibody system, and the sub-domains are connected by kinematic constraints. Consequently, all the techniques applicable to the enforcement of constraints in multibody systems become applicable to the present problem. In particular, it is shown that a combination of the localized Lagrange multiplier technique with the augmented Lagrange formulation leads to interesting solution strategies. The proposed algorithm is compared with the well-known FETI approach with regards to convergence and efficiency characteristics. The present algorithm is relatively simple and leads to improved convergence and efficiency characteristics. Finally, implementation on a parallel computer was conducted for the proposed approach.

  14. Framework and algorithms for illustrative visualizations of time-varying flows on unstructured meshes

    DOE PAGESBeta

    Rattner, Alexander S.; Guillen, Donna Post; Joshi, Alark; Garimella, Srinivas

    2016-03-17

    Photo- and physically realistic techniques are often insufficient for visualization of fluid flow simulations, especially for 3D and time-varying studies. Substantial research effort has been dedicated to the development of non-photorealistic and illustration-inspired visualization techniques for compact and intuitive presentation of such complex datasets. However, a great deal of work has been reproduced in this field, as many research groups have developed specialized visualization software. Additionally, interoperability between illustrative visualization software is limited due to diverse processing and rendering architectures employed in different studies. In this investigation, a framework for illustrative visualization is proposed, and implemented in MarmotViz, a ParaViewmore » plug-in, enabling its use on a variety of computing platforms with various data file formats and mesh geometries. Region-of-interest identification and feature-tracking algorithms incorporated into this tool are described. Implementations of multiple illustrative effect algorithms are also presented to demonstrate the use and flexibility of this framework. Here, by providing an integrated framework for illustrative visualization of CFD data, MarmotViz can serve as a valuable asset for the interpretation of simulations of ever-growing scale.« less

  15. Generalized Framework and Algorithms for Illustrative Visualization of Time-Varying Data on Unstructured Meshes

    SciTech Connect

    Alexander S. Rattner; Donna Post Guillen; Alark Joshi

    2012-12-01

    Photo- and physically-realistic techniques are often insufficient for visualization of simulation results, especially for 3D and time-varying datasets. Substantial research efforts have been dedicated to the development of non-photorealistic and illustration-inspired visualization techniques for compact and intuitive presentation of such complex datasets. While these efforts have yielded valuable visualization results, a great deal of work has been reproduced in studies as individual research groups often develop purpose-built platforms. Additionally, interoperability between illustrative visualization software is limited due to specialized processing and rendering architectures employed in different studies. In this investigation, a generalized framework for illustrative visualization is proposed, and implemented in marmotViz, a ParaView plugin, enabling its use on variety of computing platforms with various data file formats and mesh geometries. Detailed descriptions of the region-of-interest identification and feature-tracking algorithms incorporated into this tool are provided. Additionally, implementations of multiple illustrative effect algorithms are presented to demonstrate the use and flexibility of this framework. By providing a framework and useful underlying functionality, the marmotViz tool can act as a springboard for future research in the field of illustrative visualization.

  16. Statistical Methods for Tissue Array Images – Algorithmic Scoring and Co-training

    PubMed Central

    Yan, Donghui; Wang, Pei; Knudsen, Beatrice S.; Linden, Michael; Randolph, Timothy W.

    2012-01-01

    Recent advances in tissue microarray technology have allowed immunohistochemistry to become a powerful medium-to-high throughput analysis tool, particularly for the validation of diagnostic and prognostic biomarkers. However, as study size grows, the manual evaluation of these assays becomes a prohibitive limitation; it vastly reduces throughput and greatly increases variability and expense. We propose an algorithm—Tissue Array Co-Occurrence Matrix Analysis (TACOMA)—for quantifying cellular phenotypes based on textural regularity summarized by local inter-pixel relationships. The algorithm can be easily trained for any staining pattern, is absent of sensitive tuning parameters and has the ability to report salient pixels in an image that contribute to its score. Pathologists’ input via informative training patches is an important aspect of the algorithm that allows the training for any specific marker or cell type. With co-training, the error rate of TACOMA can be reduced substantially for a very small training sample (e.g., with size 30). We give theoretical insights into the success of co-training via thinning of the feature set in a high dimensional setting when there is “sufficient” redundancy among the features. TACOMA is flexible, transparent and provides a scoring process that can be evaluated with clarity and confidence. In a study based on an estrogen receptor (ER) marker, we show that TACOMA is comparable to, or outperforms, pathologists’ performance in terms of accuracy and repeatability. PMID:22984376

  17. On the use of multi-algorithm, genetically adaptive multi-objective method for multi-site calibration of the SWAT model

    SciTech Connect

    Zhang, Xuesong; Srinivasan, Raghavan; Van Liew, M.

    2010-04-15

    With the availability of spatially distributed data, distributed hydrologic models are increasingly used for simulation of spatially varied hydrologic processes to understand and manage natural and human activities that affect watershed systems. Multi-objective optimization methods have been applied to calibrate distributed hydrologic models using observed data from multiple sites. As the time consumed by running these complex models is increasing substantially, selecting efficient and effective multi-objective optimization algorithms is becoming a nontrivial issue. In this study, we evaluated a multi-algorithm, genetically adaptive multi-objective method (AMALGAM) for multi-site calibration of a distributed hydrologic model—Soil and Water Assessment Tool (SWAT), and compared its performance with two widely used evolutionary multi-objective optimization (EMO) algorithms (i.e. Strength Pareto Evolutionary Algorithm 2 (SPEA2) and Non-dominated Sorted Genetic Algorithm II (NSGA-II)). In order to provide insights into each method’s overall performance, these three methods were tested in four watersheds with various characteristics. The test results indicate that the AMALGAM can consistently provide competitive or superior results compared with the other two methods. The multi-method search framework of AMALGAM, which can flexibly and adaptively utilize multiple optimization algorithms, makes it a promising tool for multi-site calibration of the distributed SWAT. For practical use of AMALGAM, it is suggested to implement this method in multiple trials with relatively small number of model runs rather than run it once with long iterations. In addition, incorporating different multiobjective optimization algorithms and multi-mode search operators into AMALGAM deserves further research.

  18. Library of Continuation Algorithms

    2005-03-01

    LOCA (Library of Continuation Algorithms) is scientific software written in C++ that provides advanced analysis tools for nonlinear systems. In particular, it provides parameter continuation algorithms. bifurcation tracking algorithms, and drivers for linear stability analysis. The algorithms are aimed at large-scale applications that use Newton’s method for their nonlinear solve.

  19. A computational procedure for multibody systems including flexible beam dynamics

    NASA Technical Reports Server (NTRS)

    Downer, J. D.; Park, K. C.; Chiou, J. C.

    1990-01-01

    A computational procedure suitable for the solution of equations of motions for flexible multibody systems has been developed. The flexible beams are modeled using a fully nonlinear theory which accounts for both finite rotations and large deformations. The present formulation incorporates physical measures of conjugate Cauchy stress and covariant strain increments. As a consequence, the beam model can easily be interfaced with real-time strain measurements and feedback control systems. A distinct feature of the present work is the computational preservation of total energy for undamped systems; this is obtained via an objective strain increment/stress update procedure combined with an energy-conserving time integration algorithm which contains an accurate update of angular orientations. The procedure is demonstrated via several example problems.

  20. A flexible and configurable system to test accelerator magnets

    SciTech Connect

    Jerzy M. Nogiec et al.

    2001-07-20

    Fermilab's accelerator magnet R and D programs, including production of superconducting high gradient quadrupoles for the LHC insertion regions, require rigorous yet flexible magnetic measurement systems. Measurement systems must be capable of handling various types of hardware and extensible to all measurement technologies and analysis algorithms. A tailorable software system that satisfies these requirements is discussed. This single system, capable of distributed parallel signal processing, is built on top of a flexible component-based framework that allows for easy reconfiguration and run-time modification. Both core and domain-specific components can be assembled into various magnet test or analysis systems. The system configured to comprise a rotating coil harmonics measurement is presented. Technologies as Java, OODB, XML, JavaBeans, software bus and component-based architectures are used.

  1. Analytical dynamic solution of a flexible cable-suspended manipulator

    NASA Astrophysics Data System (ADS)

    Bamdad, Mahdi

    2013-12-01

    Cable-suspended manipulators are used in large scale applications with, heavy in weight and long in span cables. It seems impractical to maintain cable assumptions of smaller robots for large scale manipulators. The interactions among the cables, platforms and actuators can fully evaluate the coupled dynamic analysis. The structural flexibility of the cables becomes more pronounced in large manipulators. In this paper, an analytic solution is provided to solve cable vibration. Also, a closed form solution can be adopted to improve the dynamic response to flexibility. The output is provided by the optimal torque generation subject to the actuator limitations in a mechatronic sense. Finally, the performance of the proposed algorithm is examined through simulations.

  2. Dedalus: Flexible framework for spectrally solving differential equations

    NASA Astrophysics Data System (ADS)

    Burns, Keaton; Brown, Ben; Lecoanet, Daniel; Oishi, Jeff; Vasil, Geoff

    2016-03-01

    Dedalus solves differential equations using spectral methods. It is designed to solve initial-value, boundary-value, and eigenvalue problems involving nearly arbitrary equations sets and implements a highly flexible spectral framework that can simulate many domains and custom equations. Its primary features include symbolic equation entry, spectral domain discretization, multidimensional parallelization, implicit-explicit timestepping, and flexible analysis with HDF5. The code is written primarily in Python and features an easy-to-use interface, including text-based equation entry. The numerical algorithm produces highly sparse systems for a wide variety of equations on spectrally-discretized domains; these systems are efficiently solved by Dedalus using compiled libraries and multidimensional parallelization through MPI.

  3. Graphene-based materials for flexible supercapacitors.

    PubMed

    Shao, Yuanlong; El-Kady, Maher F; Wang, Lisa J; Zhang, Qinghong; Li, Yaogang; Wang, Hongzhi; Mousavi, Mir F; Kaner, Richard B

    2015-06-01

    The demand for flexible/wearable electronic devices that have aesthetic appeal and multi-functionality has stimulated the rapid development of flexible supercapacitors with enhanced electrochemical performance and mechanical flexibility. After a brief introduction to flexible supercapacitors, we summarize current progress made with graphene-based electrodes. Two recently proposed prototypes for flexible supercapacitors, known as micro-supercapacitors and fiber-type supercapacitors, are then discussed. We also present our perspective on the development of graphene-based electrodes for flexible supercapacitors. PMID:25898904

  4. The BR eigenvalue algorithm

    SciTech Connect

    Geist, G.A.; Howell, G.W.; Watkins, D.S.

    1997-11-01

    The BR algorithm, a new method for calculating the eigenvalues of an upper Hessenberg matrix, is introduced. It is a bulge-chasing algorithm like the QR algorithm, but, unlike the QR algorithm, it is well adapted to computing the eigenvalues of the narrowband, nearly tridiagonal matrices generated by the look-ahead Lanczos process. This paper describes the BR algorithm and gives numerical evidence that it works well in conjunction with the Lanczos process. On the biggest problems run so far, the BR algorithm beats the QR algorithm by a factor of 30--60 in computing time and a factor of over 100 in matrix storage space.

  5. Flexible Gating of Contextual Influences in Natural Vision

    PubMed Central

    Coen-Cagli, R.; Kohn, A.; Schwartz, O.

    2015-01-01

    Identical sensory inputs can be perceived as strikingly different when embedded in distinct contexts. Neural responses to simple stimuli are also modulated by context, but the contribution of this modulation to the processing of natural sensory input is unclear. We measured surround suppression, a quintessential contextual influence, in macaque primary visual cortex with natural images. We found suppression strength varied substantially for different images. This variability was not well explained by existing descriptions of surround suppression, but it was predicted by Bayesian inference about statistical dependencies in images. In this framework, surround suppression was flexible: it was recruited when the image was inferred to contain redundancies, and substantially reduced in strength otherwise. Our results thus reveal a surprising gating of a basic, widespread cortical computation, by inference about the statistics of natural input. PMID:26436902

  6. Control of flexible robots with prismatic joints and hydraulic drives

    SciTech Connect

    Love, L.J.; Kress, R.L.; Jansen, J.F.

    1997-03-01

    The design and control of long-reach, flexible manipulators has been an active research topic for over 20 years. Most of the research to date has focused on single link, fixed length, single plane of vibration test beds. In addition, actuation has been predominantly based upon electromagnetic motors. Ironically, these elements are rarely found in the existing industrial long-reach systems. One example is the Modified Light Duty Utility Arm (MLDUA) designed and built by Spar Aerospace for Oak Ridge National Laboratory (ORNL). This arm operates in larger, underground waste storage tanks located at ORNL. The size and nature of the tanks require that the robot have a reach of approximately 15 ft and a payload capacity of 250 lb. In order to achieve these criteria, each joint is hydraulically actuated. Furthermore, the robot has a prismatic degree-of-freedom to ease deployment. When fully extended, the robot`s first natural frequency is 1.76 Hz. Many of the projected tasks, coupled with the robot`s flexibility, present an interesting problem. How will many of the existing flexure control algorithms perform on a hydraulic, long-reach manipulator with prismatic links? To minimize cost and risk of testing these algorithms on the MLDUA, the authors have designed a new test bed that contains many of the same elements. This manuscript described a new hydraulically actuated, long-reach manipulator with a flexible prismatic link at ORNL. Focus is directed toward both modeling and control of hydraulic actuators as well as flexible links that have variable natural frequencies.

  7. Algorithmic synthesis using Python compiler

    NASA Astrophysics Data System (ADS)

    Cieszewski, Radoslaw; Romaniuk, Ryszard; Pozniak, Krzysztof; Linczuk, Maciej

    2015-09-01

    This paper presents a python to VHDL compiler. The compiler interprets an algorithmic description of a desired behavior written in Python and translate it to VHDL. FPGA combines many benefits of both software and ASIC implementations. Like software, the programmed circuit is flexible, and can be reconfigured over the lifetime of the system. FPGAs have the potential to achieve far greater performance than software as a result of bypassing the fetch-decode-execute operations of traditional processors, and possibly exploiting a greater level of parallelism. This can be achieved by using many computational resources at the same time. Creating parallel programs implemented in FPGAs in pure HDL is difficult and time consuming. Using higher level of abstraction and High-Level Synthesis compiler implementation time can be reduced. The compiler has been implemented using the Python language. This article describes design, implementation and results of created tools.

  8. 26 CFR 1.7874-3T - Substantial business activities (temporary).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... rules in § 1.7874-2T(g), as contained in 26 CFR part 1 revised as of April 12, 2012, or the rules set... 26 Internal Revenue 13 2013-04-01 2013-04-01 false Substantial business activities (temporary). 1... Substantial business activities (temporary). (a) Scope. This section provides rules regarding whether...

  9. 20 CFR 220.29 - Work that is considered substantial gainful activity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Employment § 220.29 Work that is considered substantial gainful activity. Work is considered to be substantial gainful activity if it— (a) Involves doing significant and productive physical or mental duties... activity. 220.29 Section 220.29 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER...

  10. 20 CFR 220.29 - Work that is considered substantial gainful activity.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Employment § 220.29 Work that is considered substantial gainful activity. Work is considered to be substantial gainful activity if it— (a) Involves doing significant and productive physical or mental duties... activity. 220.29 Section 220.29 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER...

  11. 20 CFR 220.29 - Work that is considered substantial gainful activity.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Employment § 220.29 Work that is considered substantial gainful activity. Work is considered to be substantial gainful activity if it— (a) Involves doing significant and productive physical or mental duties... activity. 220.29 Section 220.29 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER...

  12. 24 CFR 247.5 - Inapplicability to substantial rehabilitation or demolition.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... rehabilitation or demolition. 247.5 Section 247.5 Housing and Urban Development Regulations Relating to Housing... Projects § 247.5 Inapplicability to substantial rehabilitation or demolition. This subpart shall not apply... project to a purchaser who purchases for the purpose of substantial rehabilitation or demolition....

  13. 26 CFR 1.103-11 - Bonds held by substantial users.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 2 2011-04-01 2011-04-01 false Bonds held by substantial users. 1.103-11 Section 1.103-11 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Specifically Excluded from Gross Income § 1.103-11 Bonds held by substantial users. (a) In...

  14. 26 CFR 1.103-11 - Bonds held by substantial users.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 2 2014-04-01 2014-04-01 false Bonds held by substantial users. 1.103-11 Section 1.103-11 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Specifically Excluded from Gross Income § 1.103-11 Bonds held by substantial users. (a) In...

  15. 26 CFR 1.103-11 - Bonds held by substantial users.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 2 2013-04-01 2013-04-01 false Bonds held by substantial users. 1.103-11 Section 1.103-11 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Specifically Excluded from Gross Income § 1.103-11 Bonds held by substantial users. (a) In...

  16. 26 CFR 1.103-11 - Bonds held by substantial users.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Bonds held by substantial users. 1.103-11 Section 1.103-11 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Specifically Excluded from Gross Income § 1.103-11 Bonds held by substantial users. (a) In...

  17. 26 CFR 1.103-11 - Bonds held by substantial users.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 2 2012-04-01 2012-04-01 false Bonds held by substantial users. 1.103-11 Section 1.103-11 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Specifically Excluded from Gross Income § 1.103-11 Bonds held by substantial users. (a) In...

  18. 26 CFR 1.162-17 - Reporting and substantiation of certain business expenses of employees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Reporting and substantiation of certain business... Individuals and Corporations § 1.162-17 Reporting and substantiation of certain business expenses of employees... reporting of information on income tax returns by taxpayers who pay or incur ordinary and necessary...

  19. 24 CFR 247.5 - Inapplicability to substantial rehabilitation or demolition.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... rehabilitation or demolition. 247.5 Section 247.5 Housing and Urban Development Regulations Relating to Housing... Projects § 247.5 Inapplicability to substantial rehabilitation or demolition. This subpart shall not apply... project to a purchaser who purchases for the purpose of substantial rehabilitation or demolition....

  20. 24 CFR 247.10 - Inapplicability to substantial rehabilitation or demolition; right of disposition unimpaired.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... rehabilitation or demolition; right of disposition unimpaired. 247.10 Section 247.10 Housing and Urban... SUBSIDIZED AND HUD-OWNED PROJECTS HUD-Owned Projects § 247.10 Inapplicability to substantial rehabilitation... of substantial rehabilitation or demolition. Nothing in this subpart should be construed to affect...

  1. 24 CFR 247.5 - Inapplicability to substantial rehabilitation or demolition.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... rehabilitation or demolition. 247.5 Section 247.5 Housing and Urban Development Regulations Relating to Housing... Projects § 247.5 Inapplicability to substantial rehabilitation or demolition. This subpart shall not apply... project to a purchaser who purchases for the purpose of substantial rehabilitation or demolition....

  2. 24 CFR 247.5 - Inapplicability to substantial rehabilitation or demolition.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... rehabilitation or demolition. 247.5 Section 247.5 Housing and Urban Development Regulations Relating to Housing... Projects § 247.5 Inapplicability to substantial rehabilitation or demolition. This subpart shall not apply... project to a purchaser who purchases for the purpose of substantial rehabilitation or demolition....

  3. 24 CFR 247.10 - Inapplicability to substantial rehabilitation or demolition; right of disposition unimpaired.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... rehabilitation or demolition; right of disposition unimpaired. 247.10 Section 247.10 Housing and Urban... SUBSIDIZED AND HUD-OWNED PROJECTS HUD-Owned Projects § 247.10 Inapplicability to substantial rehabilitation... of substantial rehabilitation or demolition. Nothing in this subpart should be construed to affect...

  4. 24 CFR 247.5 - Inapplicability to substantial rehabilitation or demolition.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... rehabilitation or demolition. 247.5 Section 247.5 Housing and Urban Development Regulations Relating to Housing... Projects § 247.5 Inapplicability to substantial rehabilitation or demolition. This subpart shall not apply... project to a purchaser who purchases for the purpose of substantial rehabilitation or demolition....

  5. 32 CFR 48.302 - Substantiating evidence regarding dependency and age of dependents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... youngest child birth date as applicable to the option elected. At or before the time of his retirement, he... age of the dependents must be substantiated by a birth certificate or other competent evidence. The birth date of a member must be verified by his service record. All required substantiating evidence...

  6. 32 CFR 48.302 - Substantiating evidence regarding dependency and age of dependents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... youngest child birth date as applicable to the option elected. At or before the time of his retirement, he... age of the dependents must be substantiated by a birth certificate or other competent evidence. The birth date of a member must be verified by his service record. All required substantiating evidence...

  7. 32 CFR 48.302 - Substantiating evidence regarding dependency and age of dependents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... youngest child birth date as applicable to the option elected. At or before the time of his retirement, he... age of the dependents must be substantiated by a birth certificate or other competent evidence. The birth date of a member must be verified by his service record. All required substantiating evidence...

  8. 46 CFR 252.22 - Substantiality and extent of foreign-flag competition.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Substantiality and extent of foreign-flag competition... WORLDWIDE SERVICES Operation § 252.22 Substantiality and extent of foreign-flag competition. (a) Type and tonnage groupings. Foreign-flag competition shall be determined, as of January 1 of the year...

  9. 46 CFR 252.22 - Substantiality and extent of foreign-flag competition.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Substantiality and extent of foreign-flag competition... WORLDWIDE SERVICES Operation § 252.22 Substantiality and extent of foreign-flag competition. (a) Type and tonnage groupings. Foreign-flag competition shall be determined, as of January 1 of the year...

  10. 26 CFR 1.6043-3 - Return regarding liquidation, dissolution, termination, or substantial contraction of...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., termination, or substantial contraction of organizations exempt from taxation under section 501(a). 1.6043-3..., termination, or substantial contraction of organizations exempt from taxation under section 501(a). (a) In... organization was exempt from taxation under section 501(a) shall provide the information will respect to...

  11. What Criteria Do Child Protective Services Investigators Use to Substantiate Exposure to Domestic Violence?

    ERIC Educational Resources Information Center

    Coohey, Carol

    2007-01-01

    The primary purpose of this study is to determine whether child protective services investigators apply a recognizable set of criteria to substantiate batterers and victims of battering for exposing their children to domestic violence. Although domestic violence occurred in 35% of the 1,248 substantiated incidents of child maltreatment, only 31…

  12. 26 CFR 601.507 - Evidence required to substantiate facts alleged by a recognized representative.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 20 2014-04-01 2014-04-01 false Evidence required to substantiate facts alleged... Practice Requirements § 601.507 Evidence required to substantiate facts alleged by a recognized... perjury) that the recognized representative prepared such submission and that the facts contained...

  13. 26 CFR 601.507 - Evidence required to substantiate facts alleged by a recognized representative.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 20 2013-04-01 2013-04-01 false Evidence required to substantiate facts alleged... Practice Requirements § 601.507 Evidence required to substantiate facts alleged by a recognized... perjury) that the recognized representative prepared such submission and that the facts contained...

  14. 26 CFR 601.507 - Evidence required to substantiate facts alleged by a recognized representative.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 20 2011-04-01 2011-04-01 false Evidence required to substantiate facts alleged... Practice Requirements § 601.507 Evidence required to substantiate facts alleged by a recognized... perjury) that the recognized representative prepared such submission and that the facts contained...

  15. 26 CFR 601.507 - Evidence required to substantiate facts alleged by a recognized representative.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 20 2012-04-01 2012-04-01 false Evidence required to substantiate facts alleged... Practice Requirements § 601.507 Evidence required to substantiate facts alleged by a recognized... perjury) that the recognized representative prepared such submission and that the facts contained...

  16. 26 CFR 1.42-7 - Substantially bond-financed buildings. [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Substantially bond-financed buildings. 1.42-7 Section 1.42-7 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY INCOME TAX INCOME TAXES Credits Against Tax § 1.42-7 Substantially bond-financed buildings....

  17. 26 CFR 1.42-7 - Substantially bond-financed buildings. [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 1 2011-04-01 2009-04-01 true Substantially bond-financed buildings. 1.42-7 Section 1.42-7 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY INCOME TAX INCOME TAXES Credits Against Tax § 1.42-7 Substantially bond-financed buildings....

  18. 26 CFR 1.42-7 - Substantially bond-financed buildings. [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 1 2012-04-01 2012-04-01 false Substantially bond-financed buildings. 1.42-7 Section 1.42-7 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY INCOME TAX INCOME TAXES Credits Against Tax § 1.42-7 Substantially bond-financed buildings....

  19. 26 CFR 1.42-7 - Substantially bond-financed buildings. [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 1 2013-04-01 2013-04-01 false Substantially bond-financed buildings. 1.42-7 Section 1.42-7 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY INCOME TAX INCOME TAXES Credits Against Tax § 1.42-7 Substantially bond-financed buildings....

  20. 26 CFR 1.42-7 - Substantially bond-financed buildings. [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 1 2014-04-01 2013-04-01 true Substantially bond-financed buildings. 1.42-7 Section 1.42-7 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY INCOME TAX INCOME TAXES Credits Against Tax § 1.42-7 Substantially bond-financed buildings....

  1. 20 CFR 404.1572 - What we mean by substantial gainful activity.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false What we mean by substantial gainful activity. 404.1572 Section 404.1572 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Substantial...

  2. 20 CFR 404.1572 - What we mean by substantial gainful activity.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false What we mean by substantial gainful activity. 404.1572 Section 404.1572 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Substantial...

  3. 20 CFR 404.1572 - What we mean by substantial gainful activity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false What we mean by substantial gainful activity. 404.1572 Section 404.1572 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Substantial...

  4. 20 CFR 404.1572 - What we mean by substantial gainful activity.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false What we mean by substantial gainful activity. 404.1572 Section 404.1572 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Substantial...

  5. 20 CFR 404.1572 - What we mean by substantial gainful activity.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false What we mean by substantial gainful activity. 404.1572 Section 404.1572 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Substantial...

  6. 26 CFR 1.6043-3T - Returns regarding liquidation, dissolution, termination, or substantial contraction of...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., termination, or substantial contraction of organizations exempt from taxation under section 501(a) (temporary..., dissolution, termination, or substantial contraction of organizations exempt from taxation under section 501(a... organization no longer exempt from taxation under section 501(a) and that during the period of its...

  7. 26 CFR 1.6662-5 - Substantial and gross valuation misstatements under chapter 1.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...—(1) Substantial valuation misstatement. There is a substantial valuation misstatement if the value or... value or adjusted basis of any property claimed on a return of tax imposed under chapter 1 is 400... property-by-property basis. Assume, for example, that property A has a value of 60 but a taxpayer claims...

  8. 20 CFR 229.85 - Substantial gainful activity by blind employee or child.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false Substantial gainful activity by blind... Reductions § 229.85 Substantial gainful activity by blind employee or child. A blind employee or child who is 55 years old or older is entitled to an O/M benefit based on disability while he or she is working...

  9. 20 CFR 229.85 - Substantial gainful activity by blind employee or child.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true Substantial gainful activity by blind employee... § 229.85 Substantial gainful activity by blind employee or child. A blind employee or child who is 55 years old or older is entitled to an O/M benefit based on disability while he or she is working...

  10. 20 CFR 229.85 - Substantial gainful activity by blind employee or child.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Substantial gainful activity by blind... Reductions § 229.85 Substantial gainful activity by blind employee or child. A blind employee or child who is 55 years old or older is entitled to an O/M benefit based on disability while he or she is working...

  11. 20 CFR 229.85 - Substantial gainful activity by blind employee or child.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Substantial gainful activity by blind employee... § 229.85 Substantial gainful activity by blind employee or child. A blind employee or child who is 55 years old or older is entitled to an O/M benefit based on disability while he or she is working...

  12. 20 CFR 229.85 - Substantial gainful activity by blind employee or child.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Substantial gainful activity by blind... Reductions § 229.85 Substantial gainful activity by blind employee or child. A blind employee or child who is 55 years old or older is entitled to an O/M benefit based on disability while he or she is working...

  13. Alloy substantially free of dendrites and method of forming the same

    DOEpatents

    de Figueredo, Anacleto M.; Apelian, Diran; Findon, Matt M.; Saddock, Nicholas

    2009-04-07

    Described herein are alloys substantially free of dendrites. A method includes forming an alloy substantially free of dendrites. A superheated alloy is cooled to form a nucleated alloy. The temperature of the nucleated alloy is controlled to prevent the nuclei from melting. The nucleated alloy is mixed to distribute the nuclei throughout the alloy. The nucleated alloy is cooled with nuclei distributed throughout.

  14. On a programming language for graph algorithms

    NASA Technical Reports Server (NTRS)

    Rheinboldt, W. C.; Basili, V. R.; Mesztenyi, C. K.

    1971-01-01

    An algorithmic language, GRAAL, is presented for describing and implementing graph algorithms of the type primarily arising in applications. The language is based on a set algebraic model of graph theory which defines the graph structure in terms of morphisms between certain set algebraic structures over the node set and arc set. GRAAL is modular in the sense that the user specifies which of these mappings are available with any graph. This allows flexibility in the selection of the storage representation for different graph structures. In line with its set theoretic foundation, the language introduces sets as a basic data type and provides for the efficient execution of all set and graph operators. At present, GRAAL is defined as an extension of ALGOL 60 (revised) and its formal description is given as a supplement to the syntactic and semantic definition of ALGOL. Several typical graph algorithms are written in GRAAL to illustrate various features of the language and to show its applicability.

  15. Synthesis algorithm of VLSI multipliers for ASIC

    NASA Technical Reports Server (NTRS)

    Chua, O. H.; Eldin, A. G.

    1993-01-01

    Multipliers are critical sub-blocks in ASIC design, especially for digital signal processing and communications applications. A flexible multiplier synthesis tool is developed which is capable of generating multiplier blocks for word size in the range of 4 to 256 bits. A comparison of existing multiplier algorithms is made in terms of speed, silicon area, and suitability for automated synthesis and verification of its VLSI implementation. The algorithm divides the range of supported word sizes into sub-ranges and provides each sub-range with a specific multiplier architecture for optimal speed and area. The algorithm of the synthesis tool and the multiplier architectures are presented. Circuit implementation and the automated synthesis methodology are discussed.

  16. Lightweight flexible rooftop PV module

    SciTech Connect

    Izu, M.; Ovshinsky, H.C.; Whelan, K.

    1994-12-31

    Energy Conversion Devices, Inc. (ECD) and United Solar Systems Corp. (United Solar) are developing lightweight, flexible photovoltaic modules that can replace conventional roofing materials and be economically and aesthetically integrated into residential and commercial buildings. The modules will be fabricated from high-efficiency multi-junction a-Si alloy solar cells developed by ECD and United Solar. These cells are produced on thin, flexible, stainless steel substrates. Two types of products 1 ft by 10 ft overlapping PV shingles and 1.3 ft by 20 ft PV roof panels are being developed by United Solar and ECD, respectively. United Solar`s shingle type design uses a roof mounting procedures similar to those used with conventional asphalt shingles, while ECD`s PV panel uses mounting procedures conforming to metal roof systems. Thus, they can be installed on roof sheathings, replacing ordinary shingles or metal roofing panels, on a standard wood roof construction.

  17. Thin, Flexible IMM Solar Array

    NASA Technical Reports Server (NTRS)

    Walmsley, Nicholas

    2015-01-01

    NASA needs solar arrays that are thin, flexible, and highly efficient; package compactly for launch; and deploy into large, structurally stable high-power generators. Inverted metamorphic multijunction (IMM) solar cells can enable these arrays, but integration of this thin crystalline cell technology presents certain challenges. The Thin Hybrid Interconnected Solar Array (THINS) technology allows robust and reliable integration of IMM cells into a flexible blanket comprising standardized modules engineered for easy production. The modules support the IMM cell by using multifunctional materials for structural stability, shielding, coefficient of thermal expansion (CTE) stress relief, and integrated thermal and electrical functions. The design approach includes total encapsulation, which benefits high voltage as well as electrostatic performance.

  18. Automated design of flexible linkers.

    PubMed

    Manion, Charles; Arlitt, Ryan; Campbell, Matthew I; Tumer, Irem; Stone, Rob; Greaney, P Alex

    2016-03-14

    This paper presents a method for the systematic and automated design of flexible organic linkers for construction of metal organic-frameworks (MOFs) in which flexibility, compliance, or other mechanically exotic properties originate at the linker level rather than from the framework kinematics. Our method couples a graph grammar method for systematically generating linker like molecules with molecular dynamics modeling of linkers' mechanical response. Using this approach we have generated a candidate pool of >59,000 hypothetical linkers. We screen linker candidates according to their mechanical behaviors under large deformation, and extract fragments common to the most performant candidate materials. To demonstrate the general approach to MOF design we apply our system to designing linkers for pressure switching MOFs-MOFs that undergo reversible structural collapse after a stress threshold is exceeded. PMID:26687337

  19. Flexible Temperature Sensors on Fibers

    PubMed Central

    Sibinski, Maciej; Jakubowska, Malgorzata; Sloma, Marcin

    2010-01-01

    The aim of this paper is to present research dedicated to the elaboration of novel, miniaturized flexible temperature sensors for textronic applications. Examined sensors were manufactured on a single yarn, which ensures their high flexibility and good compatibility with textiles. Stable and linear characteristics were obtained by special technological process and applied temperature profiles. As a thermo-sensitive materials the innovative polymer compositions filled with multiwalled carbon nanotubes were used. Elaborated material was adapted to printing and dip-coating techniques to produce NTC composites. Nanotube sensors were free from tensometric effect typical for other carbon-polymer sensor, and demonstrated TCR of 0.13%/K. Obtained temperature sensors, compatible with textile structure, can be applied in rapidly developing smart textiles and be used for health and protections purposes. PMID:22163634

  20. Neural algorithms on VLSI concurrent architectures

    SciTech Connect

    Caviglia, D.D.; Bisio, G.M.; Parodi, G.

    1988-09-01

    The research concerns the study of neural algorithms for developing CAD tools with A.I. features in VLSI design activities. In this paper the focus is on optimization problems such as partitioning, placement and routing. These problems require massive computational power to be solved (NP-complete problems) and the standard approach is usually based on euristic techniques. Neural algorithms can be represented by a circuital model. This kind of representation can be easily mapped in a real circuit, which, however, features limited flexibility with respect to the variety of problems. In this sense the simulation of the neural circuit, by mapping it on a digital VLSI concurrent architecture seems to be preferrable; in addition this solution offers a wider choice with regard to algorithms characteristics (e.g. transfer curve of neural elements, reconfigurability of interconnections, etc.). The implementation with programmable components, such as transputers, allows an indirect mapping of the algorithm (one transputer for N neurons) accordingly to the dimension and the characteristics of the problem. In this way the neural algorithm described by the circuit is reduced to the algorithm that simulates the network behavior. The convergence properties of that formulation are studied with respect to the characteristics of the neural element transfer curve.