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Sample records for alkylammonium bromide gemini

  1. Structure activity relationships in alkylammonium C12-gemini surfactants used as dermal permeation enhancers.

    PubMed

    Silva, Sérgio M C; Sousa, João J S; Marques, Eduardo F; Pais, Alberto A C C; Michniak-Kohn, Bozena B

    2013-10-01

    The purpose of this study was to determine the ability and the safety of a series of alkylammonium C12-gemini surfactants to act as permeation enhancers for three model drugs, namely lidocaine HCl, caffeine, and ketoprofen. In vitro permeation studies across dermatomed porcine skin were performed over 24 h, after pretreating the skin for 1 h with an enhancer solution 0.16 M dissolved in propylene glycol. The highest enhancement ratio (enhancement ratio (ER)=5.1) was obtained using G12-6-12, resulting in a cumulative amount of permeated lidocaine HCl of 156.5 μg cm−2. The studies with caffeine and ketoprofen revealed that the most effective gemini surfactant was the one with the shorter spacer, G12-2-12. The use of the latter resulted in an ER of 2.4 and 2.2 in the passive permeation of caffeine and ketoprofen, respectively. However, Azone was found to be the most effective permeation enhancer for ketoprofen, attaining a total of 138.4 μg cm−2 permeated, 2.7-fold over controls. This work demonstrates that gemini surfactants are effective in terms of increasing the permeation of drugs, especially in the case of hydrophilic ionized compounds, that do not easily cross the stratum corneum. Skin integrity evaluation studies did not indicate the existence of relevant changes in the skin structure after the use of the permeation enhancers, while the cytotoxicity studies allowed establishing a relative cytotoxicity profile including this class of compounds, single chain surfactants, and Azone. A dependence of the toxicity to HEK and to HDF cell lines on the spacer length of the various gemini molecules was found. PMID:23959685

  2. Hydration of alkylammonium salt micelles--influence of bromide and chloride counterions.

    PubMed

    Rózycka-Roszak, B; Zyłka, R; Sarapuk, J

    2000-01-01

    The micellization process of dodecyltrimethylammonium chloride (DTAC) and bromide (DTAB) was studied. Nuclear magnetic resonance method was used. The 1H NMR and 13C NMR spectra were taken at higher and lower concentrations than the critical micelle concentrations (CMC) of the compounds studied. Chemical shifts were analysed. The studies performed were prompted by earlier calorimetric measurements which showed that there were significant qualitative and quantitative differences in the micellization process of the compounds studied. Namely, DTAB micelle dissociation was found to be an endothermic process while that of DTAC was exothermic. The differences found must be the result of differentiated influence of bromide and chloride counterions on the micellization process, including the phenomenon of micelle hydration. The objective of the work was to check whether cationic surfactant counterions can influence the micelle hydration process. Indeed, DTAB and DTAC, as monomers, exhibit similar hydrophobic hydration, but DTAB micelles are more hydrated than DTAC ones. It seems that the differences found in micellization of both salts studied may be attributed to different physicochemical properties of bromide and chloride ions, such as their mobilities and radii of their hydrated forms. Moreover, the effect of anions on the water structure must be taken into account. It is important whether the anions can be classified as water ordering kosmotropes, that hold the first hydration shell tightly, or water disordering chaotropes, that hold water molecules in that shell loosely.

  3. Density and viscosity studies of symmetrical tetra- n-alkylammonium bromides in water-ethanol mixtures at 303.15 K1

    NASA Astrophysics Data System (ADS)

    Hasan, M.; Pawar, T. B.; Sawant, A. B.

    2010-03-01

    The densities and viscosities of tetra- n-alkylammonium bromides, R4NBr (R=CH3 to C4H9), NaBPh4 and NaBr have been measured in 0, 10, 30, 50, 70, 90, and 100 wt % ethanol + water at 303.15 K. From the densities, apparent and limiting partial molar volumes of the electrolytes and ions in these mixture have been evaluated. The viscosity data have been analyzed with the help of Jones-Dole equation and the viscosity B-coefficients have been determined. The viscosity B-coefficients are further split up in to their ionic contributions.

  4. Effect of gemini (alkanediyl-α,ω-bis(dimethylcetylammonium bromide)) (16-s-16, s = 4, 5, 6) surfactants on the interaction of ninhydrin with chromium-glycylphenylalanine

    NASA Astrophysics Data System (ADS)

    Kumar, Dileep; Rub, Malik Abdul; Akram, Mohd.; Kabir-ud-Din

    2014-11-01

    The effect of gemini (alkanediyl-α,ω-bis(dimethylcetylammonium bromide)) (16-s-16, s = 4, 5, 6) surfactants on the interaction of ninhydrin with chromium(III) complex of glycylphenylalanine ([Cr(III)-Gly-Phe]2+) has been investigated using UV-visible spectrophotometer at different temperatures. The order of reaction with respect to [Cr(III)-Gly-Phe]2+ is unity while it is fractional with respect to ninhydrin. Whereas, the values of rate constant (kψ) increase and leveling-off regions, like conventional single chain cetyltrimethylammonium bromide (CTAB) surfactant, were observed with geminis, later produces a third region of increasing kψ at higher gemini surfactant concentrations. This unusual third-region effect of the gemini micelles is assigned to changes in their micellar morphologies. The results obtained in micellar media were treated in terms of pseudo-phase model. The values of thermodynamic parameters (Ea, ΔH# and ΔS#) and binding constants (KA and KNin) have been evaluated.

  5. Effect of gemini (alkanediyl-α,ω-bis(dimethylcetylammonium bromide)) (16-s-16, s=4, 5, 6) surfactants on the interaction of ninhydrin with chromium-glycylphenylalanine.

    PubMed

    Kumar, Dileep; Rub, Malik Abdul; Akram, Mohd; Kabir-ud-Din

    2014-11-11

    The effect of gemini (alkanediyl-α,ω-bis(dimethylcetylammonium bromide)) (16-s-16, s=4, 5, 6) surfactants on the interaction of ninhydrin with chromium(III) complex of glycylphenylalanine ([Cr(III)-Gly-Phe]2+) has been investigated using UV-visible spectrophotometer at different temperatures. The order of reaction with respect to [Cr(III)-Gly-Phe]2+ is unity while it is fractional with respect to ninhydrin. Whereas, the values of rate constant (kψ) increase and leveling-off regions, like conventional single chain cetyltrimethylammonium bromide (CTAB) surfactant, were observed with geminis, later produces a third region of increasing kψ at higher gemini surfactant concentrations. This unusual third-region effect of the gemini micelles is assigned to changes in their micellar morphologies. The results obtained in micellar media were treated in terms of pseudo-phase model. The values of thermodynamic parameters (Ea, ΔH# and ΔS#) and binding constants (KA and KNin) have been evaluated. PMID:24878435

  6. Analysis of mixed micellar behavior of cationic gemini alkanediyl-α,ω-bis(dimethylcetylammonium bromide) series with ionic and nonionic hydrotropes in aqueous medium at different temperatures.

    PubMed

    Khan, Iqrar Ahmad; Khanam, Ahmad Jahan; Sheikh, Mohmad Shafi; Kabir-ud-Din

    2011-12-29

    The interaction between cationic symmetrical gemini alkanediyl-α,ω-bis(dimethylcetylammonium bromide) series (16-s-16, s = 5, 6, abbreviated as G5 and G6) with hydrotropes (cationic: aniline hydrochloride, para-toluidine hydrochloride, and ortho-toluidine hydrochloride; nonionic: phenol, resorcinol, and pyrogallol) in aqueous medium has been investigated at four different temperatures ranging from 298.15 to 313.15 K. Different physicochemical parameters such as critical micelle concentration (cmc), interaction parameter (β(m), an energetic parameter that represents the excess Gibbs free energy of mixing), activity coefficients (f(i)), mole fraction of hydrotrope in mixed micelles at ideal mixing conditions (X(1)(ideal))(,) excess free energy of mixing (Δ(mix)G(E)), standard enthalpy (Δ(mic)H°), entropy (Δ(mic)S°), and Gibbs free energy (Δ(mic)G°) of micellization were evaluated and then intracompared. For further understanding, similar studies were carried out with their conventional counterpart cetyltrimethyl ammonium bromide (CTAB) and then compared. The bulk behaviors were explored using different theoretical models of Clint, Rubingh, and Motomura for justification and comparison of results of different binary combinations of hydrotropes with the gemini series and CTAB. Synergistic interaction was observed in all binary combinations at all temperatures in the micelles which decreases slightly with increasing temperature. This study will give insight into the selection of surfactants in different applications as their properties get modified by interaction with hydrotropes, thus influencing their solution behavior which, in turn, modifying the phase-forming behavior, microemulsion, liquid crystal forming systems, clouding phenomenon, cleaning, and laundry processes besides solubilization. The ability of hydrotropes to dramatically alter the solubility of other molecules in a medium can be exploited for the purpose of selective encapsulation and release

  7. Synthesis and surface activities of a novel di-hydroxyl-sulfate-betaine-type zwitterionic gemini surfactants

    NASA Astrophysics Data System (ADS)

    Geng, Xiang F.; Hu, Xing Q.; Xia, Ji J.; Jia, Xue C.

    2013-04-01

    A series of novel di-hydroxyl-sulfate-betaine-type zwitterionic gemini surfactants of 1,2-bis[N-ethyl-N-(2-hydroxyl-3-sulfopropyl)-alkylammonium] alkyl betaines (DBAs-n, where s and n represent the spacer length of 2, 4 and 6 and the hydrocarbon chain length of 8, 12, 14, 16 and 18, respectively) were synthesized by reacting alkylamine with sodium 3-chloro-2-hydroxypropanesulfonate (the alternative sulphonated agent), followed by the reactions with а,ω-dibromoalkyl and then ethyl bromide. Their adsorption and aggregation properties were investigated by means of equilibrium surface tension, dynamic light-scattering (DLS) and transmission electron microscopy (TEM). DBAs-n gemini surfactants showed excellent surface activities and packed tightly at the interface. For example, the minimum CMC value for DBAs-n series was of the order of 10-5 M and the surface tension of water can be decreased as low as 22.2 mN/m. It was also found that the aggregates of DBAs-n solutions were significantly dependent on their hydrocarbon chain lengths. The aggregates changed from vesicles to entangled fiber-like micelles as the chain length increased from dodecyl to tetradecyl.

  8. Water dynamics in aqueous solutions of tetra-n-alkylammonium salts: hydrophobic and Coulomb interactions disentangled.

    PubMed

    van der Post, Sietse T; Scheidelaar, Stefan; Bakker, Huib J

    2013-12-01

    We studied the effects of tetra-n-alkylammonium bromide (N(C(n)H(2n+1))(4)(+)Br(-)) salts on the dynamics of water using polarization-resolved femtosecond infrared spectroscopy. With this technique, we are capable of distinguishing the response of water solvating the hydrophobic cations from that of water solvating the bromide anion. We observe that both types of ions slow down the orientational dynamics of the water molecules in their solvation shells. However, the nature of this slowdown is different for both ions. For the hydrophobic cation, we find an increasing number of retarded water molecules, scaling with the alkyl chain length. Water in the bromide solvation shell experiences a partial decay of its orientation by a fast wobbling motion, after which the remaining anisotropy decays much slower. The dynamics of the wobbling motion are observed to be dependent on the nature of the cation. For Me(4)NBr, the slow reorientation time is not concentration-dependent, and no aggregation is observed. This is in contrast to the tetra-n-alkylammonium salts with longer alkyl chains, for which the slow reorientation time of bromide-bound water molecules increases dramatically with concentration, and clusters of cations and anions appear to be formed. PMID:24228939

  9. Lipoplexes of dicationic gemini surfactants with DNA: Structural features of DNA compaction and transfection efficiency.

    PubMed

    Faizullin, D A; Zuev, Yu F; Zakharova, L Ya; Pokrovsky, A G; Korobeinikov, V A; Mukhametzyanov, T A; Konovalov, A I

    2015-01-01

    The internal structure of DNA lipoplexes with hydroxyethylated alkylammonium gemini surfactants (GS) with high transfection activity was studied by circular dichroism. It was shown that the efficiency of transfection of HEK293T cells with the pEGFP-N1 circular plasmid was different from zero only in the region of existence of chiral supramolecular DNA-GS complexes and reaches a maximum at concentrations at which the spontaneous aggregation of components is observed.

  10. Gemini Space Program emblem

    NASA Technical Reports Server (NTRS)

    1965-01-01

    The insignia of the Gemini space program is a disc of dark blue as a background for a gold Zodiac Gemini symbol. A white star on each of the two vertical curves of the Gemini symbol represent the Gemini twins, Pollux and Castor.

  11. Memorized chiral arrangement of gemini surfactant assemblies in nanometric hybrid organic-silica helices.

    PubMed

    Ryu, Naoya; Okazaki, Yutaka; Hirai, Kana; Takafuji, Makoto; Nagaoka, Shoji; Pouget, Emilie; Ihara, Hirotaka; Oda, Reiko

    2016-04-30

    Hybrid nanohelices were obtained from silicification of self-assemblies of gemini surfactants with tartrate counterions. The chiral arrangement of these non-chiral gemini surfactants was preserved in the silica matrix even after the counterion exchange for a non-chiral bromide, and was capable of inducing the chiral organisation of a non-chiral dye, methyl orange. PMID:26961377

  12. Instrumentation at Gemini Observatory

    NASA Astrophysics Data System (ADS)

    Kleinman, S. J.; Boccas, Maxime; Goodsell, Stephen J.; Gomez, Percy; Murowinski, Rick; Chené, André-Nicolas; Henderson, David

    2014-07-01

    Gemini South's instrument suite has been completely transformed since our last biennial update. We commissioned the Gemini Multi-Conjugate Adaptive Optics System (GeMS) and its associated Gemini South Adaptive Optics Imager (GSAOI) as well as Flamingos-2, our long-slit and multi-object infrared imager and spectrograph, and the Gemini Planet Imager (GPI). We upgraded the CCDs in GMOS-S, our multi-object optical imager and spectrograph, with the GMOS-N CCD upgrade scheduled for 2015. Our next instrument, the Gemini High-resolution Optical SpecTrograph (GHOST) is in its preliminary design stage and we are making plans for the instrument to follow:Gen4#3.

  13. Synthesis of organic rectorite with novel Gemini surfactants for copper removal

    NASA Astrophysics Data System (ADS)

    Han, Guocheng; Han, Yang; Wang, Xiaoying; Liu, Shijie; Sun, Runcang

    2014-10-01

    Three novel Gemini surfactants were used to prepare organic rectorite (OREC) under microwave irradiation, in comparison with single-chain surfactant ester quaternary ammonium salt (EQAS) and cetyltrimethyl ammonium bromide (CTAB). The structure and morphology of OREC were characterized by XRD, BET, FT-IR, TEM and TGA. The removal of Cu2+ on OREC from aqueous solution was performed. The results reveal that Gemini surfactants modified REC had larger interlayer distance and higher surface area than single-chain surfactants EQAS and CTAB, and the increasing amount or chain length of Gemini surfactants led to larger layer spacing and higher adsorption capacities. The adsorption behavior of Gemini surfactant modified REC can be better described by Freundlich adsorption isotherm model, with a maximum adsorption capacity of 15.16 mg g-1. The desorption and regeneration experiments indicate good reuse property of Gemini modified REC adsorbent. Therefore, this study may widen the utilization of Gemini surfactants modified layered silicates.

  14. Quaternary Alkylammonium Conjugates of Steroids: Synthesis, Molecular Structure, and Biological Studies.

    PubMed

    Brycki, Bogumił; Koenig, Hanna; Pospieszny, Tomasz

    2015-11-23

    The methods of synthesis as well as physical, spectroscopic (¹H-NMR, 13C-NMR, and FT-IR, ESI-MS), and biological properties of quaternary and dimeric quaternary alkylammonium conjugates of steroids are presented. The results were contrasted with theoretical calculations (PM5 methods) and potential pharmacological properties (PASS). Alkylammonium sterols exhibit a broad spectrum of antimicrobial activity comparable to squalamine.

  15. Quaternary Alkylammonium Conjugates of Steroids: Synthesis, Molecular Structure, and Biological Studies.

    PubMed

    Brycki, Bogumił; Koenig, Hanna; Pospieszny, Tomasz

    2015-01-01

    The methods of synthesis as well as physical, spectroscopic (¹H-NMR, 13C-NMR, and FT-IR, ESI-MS), and biological properties of quaternary and dimeric quaternary alkylammonium conjugates of steroids are presented. The results were contrasted with theoretical calculations (PM5 methods) and potential pharmacological properties (PASS). Alkylammonium sterols exhibit a broad spectrum of antimicrobial activity comparable to squalamine. PMID:26610455

  16. Gemini IRAF: Data reduction software for the Gemini telescopes

    NASA Astrophysics Data System (ADS)

    Gemini Observatory; AURA

    2016-08-01

    The Gemini IRAF package processes observational data obtained with the Gemini telescopes. It is an external package layered upon IRAF and supports data from numerous instruments, including FLAMINGOS-2, GMOS-N, GMOS-S, GNIRS, GSAOI, NIFS, and NIRI. The Gemini IRAF package is organized into sub-packages; it contains a generic tools package, "gemtools", along with instrument-specific packages. The raw data from the Gemini facility instruments are stored as Multi-Extension FITS (MEF) files. Therefore, all the tasks in the Gemini IRAF package, intended for processing data from the Gemini facility instruments, are capable of handling MEF files.

  17. Vinyl bromide

    Integrated Risk Information System (IRIS)

    Vinyl bromide ; CASRN 593 - 60 - 2 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogenic Eff

  18. Cyanogen bromide

    Integrated Risk Information System (IRIS)

    Cyanogen bromide ; CASRN 506 - 68 - 3 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogenic

  19. Hydrodynamic size of DNA/cationic gemini surfactant complex as a function of surfactant structure.

    PubMed

    Devínsky, Ferdinand; Pisárcik, Martin; Lacko, Ivan

    2009-06-01

    The present study deals with the determination of hydrodynamic size of DNA/cationic gemini surfactant complex in sodium bromide solution using the dynamic light scattering method. Cationic gemini surfactants with polymethylene spacer of variable length were used for the interaction with DNA. The scattering experiments were performed at constant DNA and sodium bromide concentrations and variable surfactant concentration in the premicellar and micellar regions as a function of surfactant spacer length. It was found that the DNA conformation strongly depends on the polymethylene spacer length as well as on the surfactant concentration relative to the surfactant critical micelle concentration. Gemini surfactant molecules with 4 methylene groups in the spacer were found to be the least efficient DNA compacting agent in the region above the surfactant cmc. Gemini molecules with the shortest spacer length (2 methylene groups) and the longest spacer length (8 methylene groups) investigated showed the most efficient DNA compaction ability. PMID:19592712

  20. Gemini primary mirror support system

    NASA Astrophysics Data System (ADS)

    Stepp, Larry M.; Huang, Eugene W.; Cho, Myung K.

    1994-06-01

    The primary mirror selected for the Gemini 8-m Telescopes is a thin meniscus made of Corning ULE(superscript TM) glass. The conceptual design of the Gemini support system has evolved in response to the properties of the meniscus mirror and the functional requirements of the Gemini Telescopes. This paper describes the design requirements, the design features, and predicted performance of this system.

  1. Legacy of Gemini

    NASA Technical Reports Server (NTRS)

    1967-01-01

    In the perspective of a single composite mission, this documentary illustrates the major accomplishments of the Gemini two man space flights and the significance of these flights to the Apollo Program. This film includes outstanding photography of the Earth and man in space.

  2. Dielectric relaxation of alkyl chains in graphite oxide and n-alkylammonium halides

    NASA Astrophysics Data System (ADS)

    Ai, Xiaoqian; Tian, Yuchen; Gu, Min; Yu, Ji; Tang, Tong B.

    2016-05-01

    The dynamic of n-alkylammonium halides and n-alkylammonium cations (n = 12, 14, 16, 18) intercalated in graphite oxide (GO) have been investigated with complex impedance spectroscopy. X-ray diffraction, X-ray photoelectron spectroscopy, Fourier-transform infrared spectroscopy, elemental analysis and thermogravimetry served to characterize the materials. The intercalated alkylammonium cations distributes as monolayers (when n = 12, 14 or 16) or bilayers (when n = 18), with their long axis parallel to GO layers, and with cations of headgroups bonded ionically to C-O- groups of GO; backbones of the confined molecules remain free. All halides and intercalation compounds suffer dielectric loss at low temperature. Arrhenius plots of the thermal dependence of the loss peaks, which are asymmetric, produce apparent activation energies that rise with increasing n. Ngai's correlated-state model helps to correct for effects of dipole-dipole interaction, leading to virtually identical values for actual activation energy of 110 meV ± 5%; the values are also almost the same as the barrier energy for internal rotation in the alkyl macromolecule. We conclude that the relaxation of the alkylammonium cations arises not from C3 reorientation of the CH3 at its headgroup, but from small-angle wobbling around its major axis, an intrinsic motion.

  3. Gemini facility calibration unit

    NASA Astrophysics Data System (ADS)

    Ramsay-Howat, Suzanne K.; Harris, John W.; Gostick, David C.; Laidlaw, Ken; Kidd, Norrie; Strachan, Mel; Wilson, Ken

    2000-08-01

    High-quality, efficient calibration instruments is a pre- requisite for the modern observatory. Each of the Gemini telescopes will be equipped with identical facility calibration units (GCALs) designed to provide wavelength and flat-field calibrations for the suite of instruments. The broad range of instrumentation planned for the telescopes heavily constrains the design of GCAL. Short calibration exposures are required over wavelengths from 0.3micrometers to 5micrometers , field sizes up to 7 arcminutes and spectral resolution from R-5 to 50,000. The output from GCAL must mimic the f-16 beam of the telescope and provide a uniform illumination of the focal plane. The calibration units are mounted on the Gemini Instrument Support Structure, two meters from the focal pane, necessitating the use of large optical components. We will discuss the opto-mechanical design of the Gemini calibration unit, with reference to those feature which allow these stringent requirements to be met. A novel reflector/diffuser unit replaces the integration sphere more normally found in calibration systems. The efficiency of this system is an order of magnitude greater than for an integration sphere. A system of two off-axis mirrors reproduces the telescope pupil and provides the 7 foot focal plane. The results of laboratory test of the uniformity and throughput of the GCAL will be presented.

  4. Gemini Scout Control Software

    SciTech Connect

    Clinton Hobart, Justin Garretson

    2010-11-23

    The Gemini Scout Control Software consists of two Windows applications that allow the Gemini Scout vehicle to be controlled by an operator. The Embedded application runs on the vehicle's Gemini Scout Control Software onboard computer and controls the vehicle's various motors and sensors. This application reports the vehicle's status and receives vehicle commands overthe local-area-network. The Embedded applicationalso allows the user to control the vehicle using a USB game-pad connected directly to the vehicle. The Operator Control Unit (OCU) application runs on an external PC and communicates with the vehicle via an Ethernet connection. The OCU application sends commands to and receives data from the Embedded application running on the vehicle. The OCU application also communicates directly with the digital video encoders and radios in order to display video from the vehicle's cameras and the status of the radio link. The OCU application has a graphical user interface (GUI) that displays the vehicle's status and allows the user to change various vehicle settings. Finally, the OCU application receives input from a USB game-pad connected to the PC in order to control the vehicle's functions.

  5. Gemini Scout Control Software

    2010-11-23

    The Gemini Scout Control Software consists of two Windows applications that allow the Gemini Scout vehicle to be controlled by an operator. The Embedded application runs on the vehicle's Gemini Scout Control Software onboard computer and controls the vehicle's various motors and sensors. This application reports the vehicle's status and receives vehicle commands overthe local-area-network. The Embedded applicationalso allows the user to control the vehicle using a USB game-pad connected directly to the vehicle. Themore » Operator Control Unit (OCU) application runs on an external PC and communicates with the vehicle via an Ethernet connection. The OCU application sends commands to and receives data from the Embedded application running on the vehicle. The OCU application also communicates directly with the digital video encoders and radios in order to display video from the vehicle's cameras and the status of the radio link. The OCU application has a graphical user interface (GUI) that displays the vehicle's status and allows the user to change various vehicle settings. Finally, the OCU application receives input from a USB game-pad connected to the PC in order to control the vehicle's functions.« less

  6. Synthesis and crystal structures of gold nanowires with Gemini surfactants as directing agents.

    PubMed

    Xu, Feng; Hou, Hao; Gao, Zhinong

    2014-12-15

    The preparation of crystalline gold nanowires (NWs) by using gemini surfactants as directing agents through a three-step seed-mediated method is reported. Unlike the nanorods with relatively low aspect ratios (typically below 20) obtained by using cetyltrimethylammonium bromide as a directing agent, the NWs obtained in this investigation can reach up to 4.4 μm, and the largest aspect ratio is calculated to be 210. For this, each of seven different gemini surfactants are utilized as directing agents, and the length and/or aspect ratio of the NWs can be tuned by varying the hydrocarbon chain lengths of the gemini surfactants. Both single and twinned crystalline structures are elucidated by selected-area electron diffraction and high-resolution transmission electron microscopy studies. The use of gemini surfactants not only advances the synthesis of gold nanostructures, but improves the understanding of the growth mechanism for seed-mediated growth.

  7. Synthesis and crystal structures of gold nanowires with Gemini surfactants as directing agents.

    PubMed

    Xu, Feng; Hou, Hao; Gao, Zhinong

    2014-12-15

    The preparation of crystalline gold nanowires (NWs) by using gemini surfactants as directing agents through a three-step seed-mediated method is reported. Unlike the nanorods with relatively low aspect ratios (typically below 20) obtained by using cetyltrimethylammonium bromide as a directing agent, the NWs obtained in this investigation can reach up to 4.4 μm, and the largest aspect ratio is calculated to be 210. For this, each of seven different gemini surfactants are utilized as directing agents, and the length and/or aspect ratio of the NWs can be tuned by varying the hydrocarbon chain lengths of the gemini surfactants. Both single and twinned crystalline structures are elucidated by selected-area electron diffraction and high-resolution transmission electron microscopy studies. The use of gemini surfactants not only advances the synthesis of gold nanostructures, but improves the understanding of the growth mechanism for seed-mediated growth. PMID:25257473

  8. Efficient Planar Heterojunction Perovskite Solar Cells Based on Formamidinium Lead Bromide.

    PubMed

    Hanusch, Fabian C; Wiesenmayer, Erwin; Mankel, Eric; Binek, Andreas; Angloher, Philipp; Fraunhofer, Christina; Giesbrecht, Nadja; Feckl, Johann M; Jaegermann, Wolfram; Johrendt, Dirk; Bein, Thomas; Docampo, Pablo

    2014-08-21

    The development of medium-bandgap solar cell absorber materials is of interest for the design of devices such as tandem solar cells and building-integrated photovoltaics. The recently developed perovskite solar cells can be suitable candidates for these applications. At present, wide bandgap alkylammonium lead bromide perovskite absorbers require a high-temperature sintered mesoporous TiO2 photoanode in order to function efficiently, which makes them unsuitable for some of the above applications. Here, we present for the first time highly efficient wide bandgap planar heterojunction solar cells based on the structurally related formamidinium lead bromide. We show that this material exhibits much longer diffusion lengths of the photoexcited species than its methylammonium counterpart. This results in planar heterojunction solar cells exhibiting power conversion efficiencies approaching 7%. Hence, formamidinium lead bromide is a strong candidate as a wide bandgap absorber in perovskite solar cells.

  9. The Gemini Planet Imager

    SciTech Connect

    Macintosh, B; al., e

    2006-05-02

    The next major frontier in the study of extrasolar planets is direct imaging detection of the planets themselves. With high-order adaptive optics, careful system design, and advanced coronagraphy, it is possible for an AO system on a 8-m class telescope to achieve contrast levels of 10{sup -7} to 10{sup -8}, sufficient to detect warm self-luminous Jovian planets in the solar neighborhood. Such direct detection is sensitive to planets inaccessible to current radial-velocity surveys and allows spectral characterization of the planets, shedding light on planet formation and the structure of other solar systems. We have begun the construction of such a system for the Gemini Observatory. Dubbed the Gemini Planet Imager (GPI), this instrument should be deployed in 2010 on the Gemini South telescope. It combines a 2000-actuator MEMS-based AO system, an apodized-pupil Lyot coronagraph, a precision infrared interferometer for real-time wavefront calibration at the nanometer level, and a infrared integral field spectrograph for detection and characterization of the target planets. GPI will be able to achieve Strehl ratios > 0.9 at 1.65 microns and to observe a broad sample of science targets with I band magnitudes less than 8. In addition to planet detection, GPI will also be capable of polarimetric imaging of circumstellar dust disks, studies of evolved stars, and high-Strehl imaging spectroscopy of bright targets. We present here an overview of the GPI instrument design, an error budget highlighting key technological challenges, and models of the system performance.

  10. Project Gemini online digital archive

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2012-01-01

    An archive containing the first high-resolution digital scans of the original flight films from Project Gemini, the second U.S. human spaceflight program, was unveiled by the NASA Johnson Space Center and Arizona State University's (ASU) School of Earth and Space Exploration on 6 January. The archive includes images from 10 flights. Project Gemini, which ran from 1964 to 1966, followed Project Mercury and preceded the Apollo spacecraft. Mercury and Apollo imagery are also available through ASU. For more information, see http://tothemoon.ser.asu.edu/gallery/gemini and http://apollo.sese.asu.edu/index.html.

  11. Janus and Gemini Nanoplates

    NASA Astrophysics Data System (ADS)

    Cheng, Zhengdong; Mejia, Andres; Chang, Ya-Wen; He, Peng; Diaz, Agustin; Clearfield, Abraham

    2011-03-01

    Janus particles were used to make stable Pickering emulsions (emulsions stabilized by particles). Here we demonstrated a novel method to produce high aspect ratio Janus plates with atomic thickness. Gemini plates with only the edges functionalized are also fabricated. These novel nanoplates are observed to have super surface activity. Most importantly, these particles overcome the two opposite effects in the stabilization of Pickering emulsions using spherical particles: stabilization requires particles as small as possible; but smaller particles are easy to escape the interface due to Brownian motion since the adsorption energy to the oil-water interface is proportional to the diameter of the spheres. Our nanoplates have a large aspect ratio due to the extremely thin thickness, which offers extraordinary stability to the liquid film between two emulsions to prevent coalescence. In the meantime, their large lateral surface area offers strong adsorption energy at the oil-water interface.

  12. Gemini 9 spacecraft recovery operations

    NASA Technical Reports Server (NTRS)

    1966-01-01

    The Gemini 9-A spacecraft, with Astronauts Thomas Stafford and Eugene Cernan still inside, in water as the aircraft carrier U.S.S. Wasp, the recovery ship, comes alongside to recover the astronauts and their spaceship.

  13. Application of an alkylammonium method for characterization of phyllosilicates in CI chondrites

    NASA Technical Reports Server (NTRS)

    Golden, D. C.; Ming, D. W.; Zolensky, M. E.; Yang, S. V.

    1994-01-01

    Many meteorites and interplanetary dust particles (IDP's) with primitive compositions contain significant amounts of phyllosilicates, which are generally interpreted as evidence of protoplanetary aqueous alteration at an early period in the solar system. These meteorites are chondrites of the carbonaceous and ordinary varieties. Characterization of phyllosilicates in these materials is important because of the important physico-chemical information they hold, e.g., from well characterized phyllosilicates, thermodynamic stability relations and hence the conditions of formation of phyllosilicates in the parent body of the meteorite can be predicted. Although we are at a rudimentary level of understanding of the minerals resulting from the aqueous alteration in the early solar nebula, we know that the most common phyllosilicates present in chondritic extraterrestrial materials are serpentines, smectites, chlorites, and micas. The characterization of fine grained minerals in meteorites and IDP's rely heavily on electron beam instruments, especially transmission electron microscopy (TEM). Typically, phyllosilicates are identified by a combination of high resolution imaging of basal spacings, electron diffraction analysis, and chemical analysis. Smectites can be difficult to differentiate from micas because the smectites loose their interlayer water and the interlayers collapse to the same basal spacing as mica in the high vacuum of the TEM. In high-resolution TEM (HRTEM) images, smectite basal spacings vary from 1 nm up to 1.5 nm, while micas show 1 or 2 nm basal spacings. Not only is it difficult to differentiate smectites from micas, but there is no way of identifying different classes of smectites in meteorites and IDP's. To differentiate smectites from micas and also to recognize the charge differences among smectites, an alkylammonium method can be employed because the basal spacings of alkylammonium saturated smectites expand as a function of alkylamine chain

  14. The Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Graham, James R.; Macintosh, Bruce; Perrin, Marshall D.; Ingraham, Patrick; Konopacky, Quinn M.; Marois, Christian; Poyneer, Lisa; Bauman, Brian; Barman, Travis; Burrows, Adam Seth; Cardwell, Andrew; Chilcote, Jeffrey K.; De Rosa, Robert John J.; Dillon, Daren; Doyon, Rene; Dunn, Jennifer; Erikson, Darren; Fitzgerald, Michael P.; Gavel, Donald; Goodsell, Stephen J.; Hartung, Markus; Hibon, Pascale; Kalas, Paul; Larkin, James E.; Maire, Jerome; Marchis, Franck; Marley, Mark S.; McBride, James; Millar-Blanchaer, Max; Morzinski, Kathleen M.; Nielsen, Eric L.; Norton, Andew; Oppenheimer, Rebecca; Palmer, David; Patience, Jenny; Pueyo, Laurent; Rantakyro, Fredrik; Sadakuni, Naru; Saddlemeyer, Leslie; Savransky, Dmitry; Serio, Andrew W.; Soummer, Remi; Sivaramakrishnan, Anand; Song, Inseok; Thomas, Sandrine; Wallace, J. Kent; Wang, Jason; Wiktorowicz, Sloane; Wolff, Schulyer; Gpi/Gpies Team

    2015-01-01

    The Gemini Planet Imager (GPI) is a dedicated facility for directly imaging and spectroscopically characterizing extrasolar planets. It combines a very high-order adaptive optics system, a diffraction-suppressing coronagraph, and an integral field spectrograph with low spectral resolution but high spatial resolution. Every aspect of GPI has been tuned for maximum sensitivity to faint planets near bright stars. GPI has undergone a year of commissioning, verification, and calibration work. We have achieved an estimated H-band contrast (5-sigma) of 106 at 0.75 arcseconds and 105 at 0.35 arcseconds in spectral mode, and suppression of unpolarized starlight by a factor of 800 in imaging polarimetry mode. Early science observations include study of the spectra of β Pic b and HR 8799, orbital investigations of β Pic b and PZ Tel, and observations of the debris disk systems associated with β Pic, AU Mic, and HR 4796A. An 890-hour exoplanet survey with GPI is scheduled to begin in late 2014. A status report for the campaign will be presented.

  15. Gemini Alkyldeoxy-D-Glucitolammonium Salts as Modern Surfactants and Microbiocides: Synthesis, Antimicrobial and Surface Activity, Biodegradation

    PubMed Central

    Brycki, Bogumił; Szulc, Adrianna

    2014-01-01

    Dimeric quaternary alkylammonium salts possess a favourable surface and antimicrobial activity. In this paper we describe synthesis, spectroscopic analysis, surface and antimicrobial activity as well as biodegradability of polymethylene-α,ω-bis(N,N-dialkyl-N-deoxy-D-glucitolammonium iodides), a new group of dimeric quaternary ammonium salts. This new group of gemini surfactants can be produced from chemicals which come from renewable sources. The structure of products has been determined by the FTIR and 1H and 13C NMR spectroscopy. The biodegradability, surface activity and antimicrobial efficacy against Escherichia coli, Staphylococcus aureus, Candida albicans, Aspergillus niger and Penicillium chrysogenum were determined. The influence of the number of alkyl chains and their lengths on surface and antimicrobial properties has been shown. In general, dimeric quaternary alkyldeoxy-D-glucitolammonium salts with long alkyl substituents show favourable surface properties and an excellent antimicrobial activity. PMID:24416314

  16. Recovery of Gemini 4 spacecraft and astronauts

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Recovery of Gemini 4 spacecraft and astronauts. Views include Astronaut James A. McDivitt, command pilot of the Gemini 4 space flight, sitting in life raft awaiting pickup by helicopter from the recovery ship, the aircraft carrier U.S.S. Wasp (33490); Navy frogmen stand on the flotation collar of the Gemini 4 spacecraft during recovery operations (33491).

  17. Index maps for Gemini earth photography

    NASA Technical Reports Server (NTRS)

    Giddings, L. E.

    1975-01-01

    Index maps for the Gemini missions are presented; these are for the Gemini 3 through Gemini 12 missions. The maps are divided into four sections: the whole earth; the Western Hemisphere and eastern Pacific Ocean; Africa, India, and the Near East; and Asia, Australia, and the Pacific Ocean.

  18. El Observatorio Gemini - Status actual

    NASA Astrophysics Data System (ADS)

    Levato, H.

    Se hace una breve descripción de la situación actual del Observatorio Gemini y de las últimas decisiones del Board para incrementar la eficiencia operativa. Se hace también una breve referencia al uso argentino del observatorio.

  19. [Bromide encephalopathies (author's transl)].

    PubMed

    Loubrieu, G; Bourin, M; Bizière, K; Breteau, M; Autret, A

    1979-07-01

    Bromide encephalopathies are frequently reported in Northern America and Great Britain. There is no characteristic clinical pattern, the neurological symptoms are multiple, this is readily explained by the diffusion of bromide ions to all regions in the central nervous system. An accurate history (bromide intake, followed by the slow onset of digestive and neuropsychiatric symptoms) as well as an apparent hyperchloremia are of the greatest aid in suggesting the diagnosis. The incidence of this type of intoxication is greater in women over 50. The association of a salt free diet to bromide therapy favors the onset of clinical symptoms because of the competition between bromide and chloride at the choroid plexus and at the renal tubule.

  20. AO operations at Gemini South

    NASA Astrophysics Data System (ADS)

    Marin, Eduardo; Cardwell, Andrew; Pessev, Peter

    2014-08-01

    The 8m Gemini South telescope is entering an exciting new era of AO operations, which put it at the forefront of astronomical AO in terms of both wide field AO, and extreme-AO systems. Major milestones achieved were the successful commissioning of GeMS, in 2012, and GPI, in late 2013 and early 2014. Currently we are operating two of the worlds most advanced astronomical AO systems. Gemini, running primarily in queue, must balance the promise of AO with the demands of the community to use non-AO instruments. We discuss the current state of the two AO systems, and their operational models. The preparations that go into planning each AO run, the difficulties in scheduling around non-AO instruments, and the differences between scheduling LGS AO and non-LGS AO are discussed.

  1. The Gemini Deep Planet Survey

    NASA Astrophysics Data System (ADS)

    Lafrenière, David; Doyon, René; Marois, Christian; Nadeau, Daniel; Oppenheimer, Ben R.; Roche, Patrick F.; Rigaut, François; Graham, James R.; Jayawardhana, Ray; Johnstone, Doug; Kalas, Paul G.; Macintosh, Bruce; Racine, René

    2007-12-01

    We present the results of the Gemini Deep Planet Survey, a near-infrared adaptive optics search for giant planets and brown dwarfs around 85 nearby young stars. The observations were obtained with the Altair adaptive optics system at the Gemini North telescope, and angular differential imaging was used to suppress the speckle noise of the central star. Typically, the observations are sensitive to angular separations beyond 0.5" with 5 σ contrast sensitivities in magnitude difference at 1.6 μm of 9.5 at 0.5", 12.9 at 1", 15.0 at 2", and 16.5 at 5". These sensitivities are sufficient to detect planets more massive than 2 MJ with a projected separation in the range 40-200 AU around a typical target. Second-epoch observations of 48 stars with candidates (out of 54) have confirmed that all candidates are unrelated background stars. A detailed statistical analysis of the survey results is presented. Assuming a planet mass distribution dn/dm~m-1.2 and a semimajor-axis distribution dn/da~a-1, the 95% credible upper limits on the fraction of stars with at least one planet of mass 0.5-13 MJ are 0.28 for the range 10-25 AU, 0.13 for 25-50 AU, and 0.093 for 50-250 AU; this result is weakly dependent on the semimajor-axis distribution power-law index. The 95% credible interval for the fraction of stars with at least one brown dwarf companion having a semimajor axis in the range 25-250 AU is 0.019+0.083-0.015, irrespective of any assumption on the mass and semimajor-axis distributions. The observations made as part of this survey have resolved the stars HD 14802, HD 166181, and HD 213845 into binaries for the first time. Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the Particle Physics and Astronomy Research Council (United Kingdom), the National

  2. Gemini surfactants with a disaccharide spacer.

    PubMed

    Menger, F M; Mbadugha, B N

    2001-02-01

    A gemini surfactant is an amphiphile possessing (in sequence) the following: hydrocarbon tail/polar group/spacer/polar group/hydrocarbon tail. Widespread interest in geminis has emerged recently from both industrial and academic laboratories. In the present contribution, two related families of geminis have been synthesized, both with trehalose, a disaccharide, as a polar spacer. One family, Series-A, is nonionic and has amide groups separating the long chains from the trehalose spacer. The other family, Series-B, has quaternary ammonium ions connecting the long chains to the trehalose spacer. It was found that Series-A geminis are water insoluble despite the two amides and multiple hydroxyls. When hydrated or extruded, these geminis form microscopically visible vesicular and tubular structures above their transition temperatures (which were determined calorimetrically). Insoluble monomolecular films, constructed from these geminis, have interfacial areas that are dominated by the sugar spacer although intermolecular chain/chain interactions seem to stabilize the films. Thus, the behavior of Series-A geminis in many ways parallels that of phospholipids and simple double-chain surfactants. It is as if the trehalose is less of a spacer than a large but conventional headgroup. In contrast, cationic Series-B geminis are water soluble and form micelles with critical micelle concentrations an order of magnitude lower than that of corresponding conventional surfactants. Molecular modeling using the Amber force field explains the difference in properties between the two families of geminis. Series-A are tubular in shape and thus prefer bilayer packing as do other amphiphiles in which the headgroups are similar in width to the sum of the tail diameters. Series-B geminis are conical-shaped and pack more readily into spherical micelles. This work entails synthesis, tensiometry, conductance, microscopy, surface balance studies, calorimetry, light scattering, and molecular

  3. D-glucose derived novel gemini surfactants: synthesis and study of their surface properties, interaction with DNA, and cytotoxicity.

    PubMed

    Kumar, Vikash; Chatterjee, Amrita; Kumar, Nupur; Ganguly, Anasuya; Chakraborty, Indranil; Banerjee, Mainak

    2014-10-01

    Four new D-glucose derived m-s-m type gemini surfactants with variable spacer and tail length have been synthesized by a simple and efficient synthetic methodology utilizing the free C-3 hydroxy group of diisopropylidene glucose. The synthetic route to these gemini surfactants with a quaternary ammonium group as polar head group involves a sequence of simple reactions including alkylation, imine formation, quaternization of amine etc. The surface properties of the new geminis were evaluated by surface tension and conductivity measurements. These gemini surfactants showed low cytotoxicity by MTT assay on HeLa cell line. The DNA binding capabilities of these surfactants were determined by agarose gel electrophoresis, fluorescence titration, and DLS experiments. The preliminary studies by agarose gel electrophoresis indicated chain length dependent DNA binding abilities, further supported by ethidium bromide exclusion experiments. Two of the D-glucose derived gemini surfactants showed effective binding with pET-28a plasmid DNA (pDNA) at relatively low N/P ratio (i.e., cationic nitrogen/DNA phosphate molar ratio).

  4. Gemini

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    (the Twins; abbrev. Gem, gen. Geminorum; area 514 sq. deg.) A northern zodiacal constellation which lies between Auriga and Canis Minor, and culminates at midnight in early January. It represents Castor and Pollux, the twin sons of Leda, Queen of Sparta, in Greek mythology, whose brotherly love was rewarded by a place among the stars. Its brightest stars were cataloged by Ptolemy (c. AD 100-175) ...

  5. Schirra, Stafford and Gemini on Deck

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Astronaut Walter H. Schirra Jr. (on right), Command pilot, climbs from his Gemini VI spacecraft as he and Astronaut Thomas P. Stafford (not in view) arrive aboard the aircraft carrier U.S.S. Wasp. They are assisted by various McDonell Douglas technicians. The Gemini VI spacecraft splashed down in the western Atlantic recover area at 10:29 a.m. (EST) December 16, 1965, after a successful 25 hr. 52 minute mission in space.

  6. Gemini 11 prime and back-up crews at Gemini Mission Simulator at Cape Kennedy

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Gemini 11 prime and back-up crews at Gemini Mission Simulator at Cape Kennedy, Florida. Left to right are Astronauts William A. Anders, back-up crew pilot; Richard F. Gordon Jr., prime crew pilot; Charles Conrad Jr. (foot on desk), prime crew command pilot; and Neil A. Armstrong, back-up crew command pilot.

  7. Action of reactive oxygen species in the antifungal mechanism of gemini-pyridinium salts against yeast.

    PubMed

    Shirai, Akihiro; Ueta, Shouko; Maseda, Hideaki; Kourai, Hiroki; Omasa, Takeshi

    2012-06-01

    We previously found that the gemini quaternary salt (gemini-QUAT) containing two pyridinium residues per molecule, 3,3'- (2,7-dioxaoctane) bis (1-decylpyridinium bromide) (3DOBP-4,10) , exerted fungicidal activity against Saccharomyces cerevisiae and caused respiration inhibition and the cytoplasmic leakage of ATP, magnesium, and potassium ions. Here, we investigated how the gemini-QUAT, 3DOBP-4,10, exerts more powerful antimicrobial activity than the mono-QUAT N-cetylpyridinium chloride (CPC) and examined the association between reactive oxygen species (ROS) and the antimicrobial mechanism. Antifungal assays showed that the activity of 3DOBP-4,10 against two yeasts, S. cerevisiae and Candida albicans, was significantly elevated under aerobic conditions, and largely reduced under anaerobic conditions (nitrogen atmosphere) . Adding radical scavengers such as superoxide dismutase, catalase and potassium iodide (KI) also decreased the fungicidal activity of 3DOBP-4,10 but negligibly affected that of CPC. We measured survival under static conditions and found that the rapid fungicidal profile of 3DOBP-4,10 was lost, whereas that of CPC was slightly affected in the presence of KI. Our results suggest that 3DOBP-4,10 exerts powerful antimicrobial activity by penetrating the cell wall and membrane, which then allows oxygen to enter the cells, where it participates in the generation of intracellular ROS. The activity could thus be attributable to a synergic antimicrobial combination of the disruption of organelle membranes by the QUAT and oxidative stress imposed by ROS.

  8. Action of reactive oxygen species in the antifungal mechanism of gemini-pyridinium salts against yeast.

    PubMed

    Shirai, Akihiro; Ueta, Shouko; Maseda, Hideaki; Kourai, Hiroki; Omasa, Takeshi

    2012-06-01

    We previously found that the gemini quaternary salt (gemini-QUAT) containing two pyridinium residues per molecule, 3,3'- (2,7-dioxaoctane) bis (1-decylpyridinium bromide) (3DOBP-4,10) , exerted fungicidal activity against Saccharomyces cerevisiae and caused respiration inhibition and the cytoplasmic leakage of ATP, magnesium, and potassium ions. Here, we investigated how the gemini-QUAT, 3DOBP-4,10, exerts more powerful antimicrobial activity than the mono-QUAT N-cetylpyridinium chloride (CPC) and examined the association between reactive oxygen species (ROS) and the antimicrobial mechanism. Antifungal assays showed that the activity of 3DOBP-4,10 against two yeasts, S. cerevisiae and Candida albicans, was significantly elevated under aerobic conditions, and largely reduced under anaerobic conditions (nitrogen atmosphere) . Adding radical scavengers such as superoxide dismutase, catalase and potassium iodide (KI) also decreased the fungicidal activity of 3DOBP-4,10 but negligibly affected that of CPC. We measured survival under static conditions and found that the rapid fungicidal profile of 3DOBP-4,10 was lost, whereas that of CPC was slightly affected in the presence of KI. Our results suggest that 3DOBP-4,10 exerts powerful antimicrobial activity by penetrating the cell wall and membrane, which then allows oxygen to enter the cells, where it participates in the generation of intracellular ROS. The activity could thus be attributable to a synergic antimicrobial combination of the disruption of organelle membranes by the QUAT and oxidative stress imposed by ROS. PMID:22790843

  9. Denaturation of Proteins by SDS and by Tetra-alkylammonium Dodecyl Sulfates

    PubMed Central

    Lee, Andrew; Tang, Sindy K. Y.; Mace, Charles R.

    2011-01-01

    This paper describes the use of capillary electrophoresis (CE) to examine the influence of different cations (C+; C+ = Na+ and tetra-n-alkylammonium, NR4 +, where R = Me, Et, Pr, Bu) on the rates of denaturation of bovine carbonic anhydrase II (BCA) in the presence of the anionic surfactant dodecylsulfate (DS−). Analysis of the denaturation of BCA in solutions of Na+DS− and NR4 +DS− (in Tris-Gly buffer) indicated that the rates of formation of complexes of denatured BCA with DS− (BCAD-DS−n,sat) are indistinguishable and independent of the cation below the critical micellar concentration (cmc), and independent of the total concentration of DS− above the cmc. At concentrations of C+DS− above the cmc, BCA denatured with rates that depended on the cation; the rates decreased by a factor > 104, in the order Na+ ~ NMe4 + > NEt4 + > NPr4 + > NBu4 + – the same order as the values of cmc (which decrease from 4.0 mM for Na+DS− to 0.9 mM for NBu4 +DS− in Tris-Gly buffer). The relationship between values of cmc and rates of formation of BCAD-DS−n,sat suggested that the kinetics of denaturation of BCA involve the association of this protein with monomeric DS−, rather than with micelles of (C+DS−)n. A less-detailed survey of seven other proteins (α-lactalbumin, β-lactoglobulin A, β-lactoglobulin B, carboxypeptidase B, creatine phosphokinase, myoglobin, and ubiquitin) showed that the difference between Na+DS− and NR4 +DS− observed with BCA was not general. Instead, the influence of NR4 + on the association of DS− with these proteins depended on the protein. The selection of cation contributed to the properties (including composition, electrophoretic mobility, and partitioning behavior in aqueous two-phase systems) of aggregates of denatured protein and DS−. These results suggest that variation in the behavior of NR4 +DS− with changes in R may be exploited in methods for analyzing and separating mixtures of proteins. PMID:21834533

  10. Rapacuronium bromide (Organon Teknika).

    PubMed

    Plowman, A N

    1999-07-01

    Organon Teknika's rapacuronium bromide (Org-9487), the 16-N-allyl, 17-beta-propionate analog of vecuronium bromide, is in phase III clinical trials in the US and Europe for potential use as an anesthetic. It is a steroidal neuromuscular blocking drug characterized by low potency, rapid rate of block development and short time course of neuromuscular blocking action as compared with other non-depolarizing compounds [170210,221422]. A multicenter, randomized, assessor-blind, placebo-controlled, dose-finding study in patients undergoing tracheal intubation showed that the drug produced a dose dependent neuromuscular block. Doses of 1.5 to 2 mg/kg allowed rapid intubation and short duration of action [273336]. Another study showed that the drug does not cause cardiovascular side-effects [273336]. A meeting was held in Europe on 8 February 1999 to brief company employees on the registration and release of rapacuronium [319211] for which the company anticipates a launch in late 1999 [320706]. Organon estimates that the market value of Org-9487 is between dollar 100 m and dollar 250 m a year, each for Europe and the US [221422].

  11. Removal of phenol from synthetic waste water using Gemini micellar-enhanced ultrafiltration (GMEUF).

    PubMed

    Zhang, Wenxiang; Huang, Guohe; Wei, Jia; Li, Huiqin; Zheng, Rubing; Zhou, Ya

    2012-10-15

    Comprehensive studies were conducted on the phenol wastewater ultrafiltration (UF) with the help of various concentrations of cationic Gemini surfactant (N1-dodecyl-N1,N1,N2,N2-tetramethyl-N2-octylethane-1,2-diaminium bromide, CG), conventional cationic surfactant (dodecyl trimethyl ammonium bromide, DTAB), anionic surfactant (sodium dodecyl sulfate, SDS) and nonionic surfactant ((dodecyloxy)polyethoxyethanol, Brij35). A flat sheet module with polyethersulfone (PES) membrane was employed in this investigation. The effects of feed concentration (phenol and surfactant) on the retention of phenol and surfactant, permeate flux and membrane fouling by micelles were evaluated. The distribution coefficient (D), the loading of the micelles (L(m)) and the equilibrium distribution constant (K) were also utilized to estimate the micellar-enhanced ultrafiltration ability for phenol. Scanning electron microscope (SEM), Fourier transform infrared spectrometer with attenuated total reflectance accessory (ATR-FTIR) and mercury porosimeter were applied to analyze membrane surface morphology, membrane material characteristics and membrane fouling for the original and fouled membranes. Based on the above analysis, the performance of the selected Gemini surfactant was proved superior in the following aspects: retention of phenol/surfactant (peak value is 95.8% for phenol retention), permeate flux and membrane fouling with respect to other conventional surfactants possessing equal alkyl chain length. These results demonstrated that CG surfactant with exceptional structure has favorable prospects in the treatment of phenol wastewater by the micellar-enhanced ultrafiltration.

  12. Women Astronomers at Gemini: A Success Story

    NASA Astrophysics Data System (ADS)

    Rodgers, Bernadette; Jorgensen, I.; Barker, N.; Edwards, M.; Trancho, G.

    2010-01-01

    Gemini Observatory has been very successful at attracting, hiring and retaining female Scientists. We present data on the growth of the scientific staff since the start of the Observatory, and science fellow recruiting from 2006-2008. At Gemini 31% of the Science Staff holding PhDs are female compared with 13.9% within the United States. The Science Management is 75% female, as is 50% of the Gemini Directorate. This critical mass of female representation within the science staff and management appears to have had a positive effect on female recruitment and hiring. The science fellow recruitment during the past 3 years has attracted 21-38% female applicants and 57% of new hires during this period have been female scientists. Perhaps even more significant, the retention rate of female science staff at Gemini is 88%, compared to 64% for male science staff. There are likely many factors that contribute to this success, but the conclusion is that Gemini has earned a reputation in the scientific community as a place where female scientists are valued and can be successful.

  13. Interaction between dipeptide (glycyl-phenylalanine) and ninhydrin: role of CTAB and gemini (16-s-16, s=4, 5, 6) surfactant micelles.

    PubMed

    Kumar, Dileep; Rub, Malik Abdul; Akram, Mohd; Kabir-ud-Din

    2014-03-15

    The kinetics of interaction of dipeptide glycylphenylalanine (Gly-Phe) with ninhydrin have been studied by following the reaction spectrophotometrically at 70 °C and a particular pH 5.0 in the absence and presence of conventional cetyltrimethylammonium bromide (CTAB) and gemini (alkanediyl-α,ω-bis(dimethylhexadecylammonium bromide)) surfactants. The rate shows first- and fractional-order dependence on [Gly-Phe] and [ninhydrin], respectively. The surfactants were found to catalyse the reaction. Furthermore, whereas the typical rate constant (kΨ) increase and leveling-off regions are observed with geminis, just like as seen with conventional surfactants, the former produced a third region of increasing kΨ at higher concentrations. A kinetic rate law consistent with experimental results has been derived on the basis of the proposed mechanism. PMID:24461852

  14. Summary analysis of the Gemini entry aerodynamics

    NASA Technical Reports Server (NTRS)

    Whitnah, A. M.; Howes, D. B.

    1972-01-01

    The aerodynamic data that were derived in 1967 from the analysis of flight-generated data for the Gemini entry module are presented. These data represent the aerodynamic characteristics exhibited by the vehicle during the entry portion of Gemini 2, 3, 5, 8, 10, 11, and 12 missions. For the Gemini, 5, 8, 10, 11, and 12 missions, the flight-generated lift-to-drag ratios and corresponding angles of attack are compared with the wind tunnel data. These comparisons show that the flight generated lift-to-drag ratios are consistently lower than were anticipated from the tunnel data. Numerous data uncertainties are cited that provide an insight into the problems that are related to an analysis of flight data developed from instrumentation systems, the primary functions of which are other than the evaluation of flight aerodynamic performance.

  15. Iron bromide vapor laser

    NASA Astrophysics Data System (ADS)

    Sukhanov, V. B.; Shiyanov, D. V.; Trigub, M. V.; Dimaki, V. A.; Evtushenko, G. S.

    2016-03-01

    We have studied the characteristics of a pulsed gas-discharge laser on iron bromide vapor generating radiation with a wavelength of 452.9 nm at a pulse repetition frequency (PRF) of 5-30 kHz. The maximum output power amounted to 10 mW at a PRF within 5-15 kHz for a voltage of 20-25 kV applied to electrodes of the discharge tube. Addition of HBr to the medium produced leveling of the radial profile of emission. Initial weak lasing at a wavelength of 868.9 nm was observed for the first time, which ceased with buildup of the main 452.9-nm line.

  16. The Gemini Instrument Feasibilities Studies project

    NASA Astrophysics Data System (ADS)

    Hibon, Pascale; Goodsell, Stephen J.; Hardie, Kayla

    2015-01-01

    The Gemini Instrument Feasibilities Studies (GIFS) project is part of a program that will provide a number of community-created science-driven instrumentation design study reports and presentations to the observatory, conforming to a number of desired principles.By the time of the AAS, Gemini will have received a number of proposals and will be evaluating them shortly afterwards with the expectation of placing 3 or more feasibility study contracts based on a facility instrument costing between USD 8,000,000 and USD 12,000,000. These instrument studies will provide synergies with new capabilities coming online (e.g. LSST, JWST, ALMA, etc)Following the project, Gemini together with the Gemini Science and Technical Advisory Committee (STAC) and input from the wider community will decide on the top-level instrument requirements for the next facility instrument (Gen4#3) and launch a targeted Request for Proposals to design, build, test and deliver a suitable instrument. Gemini expects to release an RfP for Gen4#3 in Q4 2015.Each feasibility study will include fully developed science case(s), optical, mechanical, electronic and software design elements at the conceptual level as needed to demonstrate the technical viability. In particular, each design study will thoroughly identify and mitigate key risks.Each study team will present a status summary presentation at the 2015 Meeting on the Science and Future of Gemini held in Toronto in June 2015. The final GIFS reports and presentations are expected in Sept 2015.We will discuss the status of GIFS and the currently plans for Gen4#3.

  17. Potassium bromide-associated panniculitis.

    PubMed

    Boynosky, N A; Stokking, L B

    2014-12-01

    Two cases of panniculitis associated with administration of potassium bromide in dogs are reported. Both dogs were treated with potassium bromide for idiopathic epilepsy for over 1 year. Dose increases in both cases were associated with panniculitis, characterised by painful subcutaneous nodules in a generalised distribution over the trunk. Nodule eruption waxed and waned in one dog and was persistent in the other. In both cases, panniculitis was accompanied by lethargy and pyrexia. Panniculitis, lethargy and pyrexia resolved and failed to recur after discontinuation of potassium bromide. No other cause of panniculitis could be determined for either dog. Panniculitis has been reported after administration of potassium bromide in humans and may be a form of drug-induced erythema nodosum. To the authors' knowledge, these are the first reports of potassium bromide-associated panniculitis in dogs.

  18. Geo-Engineering through Internet Informatics (GEMINI)

    SciTech Connect

    Doveton, John H.; Watney, W. Lynn

    2003-03-06

    The program, for development and methodologies, was a 3-year interdisciplinary effort to develop an interactive, integrated Internet Website named GEMINI (Geo-Engineering Modeling through Internet Informatics) that would build real-time geo-engineering reservoir models for the Internet using the latest technology in Web applications.

  19. Gemini helium closed cycle cooling system

    NASA Astrophysics Data System (ADS)

    Lazo, Manuel; Galvez, Ramon; Rogers, Rolando; Solis, Hernan; Tapia, Eduardo; Maltes, Diego; Collins, Paul; White, John; Cavedoni, Chas; Yamasaki, Chris; Sheehan, Michael P.; Walls, Brian

    2008-07-01

    The Gemini Observatory presents the Helium Closed Cycle Cooling System that provides cooling capacity at cryogenic temperatures for instruments and detectors. It is implemented by running three independent helium closed cycle cooling circuits with several banks of compressors in parallel to continuously supply high purity helium gas to cryocoolers located about 100-120 meters apart. This poster describes how the system has been implemented, the required helium pressures and gas flow to reach cryogenic temperature, the performance it has achieved, the helium compressors and cryocoolers in use and the level of vibration the cryocoolers produce in the telescope environment. The poster also describes the new technology for cryocoolers that Gemini is considering in the development of new instruments.

  20. Gemini planet imager one button approach

    NASA Astrophysics Data System (ADS)

    Dunn, Jennifer; Kerley, Dan; Saddlemyer, Leslie; Smith, Malcolm; Wooff, Robert; Savransky, Dmitry; Palmer, David; Macintosh, Bruce; Weiss, Jason; Quiroz, Carlos; Rantakyrö, Fredrik T.; Goodsell, Stephen J.

    2014-07-01

    The Gemini Planet Imager (GPI) is an "extreme" adaptive optics coronagraph system that is now on the Gemini South telescope in Chile. This instrument is composed of three different systems that historically have been separate instruments. These systems are the extreme Adaptive Optics system, with deformable mirrors, including a high-order 64x64 element MEMS system; the Science Instrument, which is a near-infrared integral field spectrograph; and the Calibration system, a precision IR wavefront sensor that also holds key coronagraph components. Each system coordinates actions that require precise timing. The observatory is responsible for starting these actions and has typically done this asynchronously across independent systems. Despite this complexity we strived to provide an interface that is as close to a onebutton approach as possible. This paper will describe the sequencing of these systems both internally and externally through the observatory.

  1. Gemini 4 Recovery with Green Marker Dye

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Overhead view of the Gemini 4 spacecraft showing the yellow flotation collar used to stabilize the spacecraft in choppy seas. The green marker dye is highly visible from the air and is used as a locating aid. A crewmember is being hoisted aboard a U.S. Navy helicopter during recovery operations following the successful four-day, 62 revolution mission highlighted by Ed White's space walk.

  2. Gemini 10 prime crew during post flight press conference

    NASA Technical Reports Server (NTRS)

    1966-01-01

    At podium during Gemini 10 press conference are (l-r) Dr. Robert C. Seamans, Astronauts John Young and Michael Collins and Dr. Robert R. Gilruth (39895); Wide angle view of the Manned Spacecraft Center (MSC) News Center during the Gemini 10 prime crew post flight press conference (38786); Astronaut Young draws diagram on chalk board of tethered extravehicular activity accomplished during Gemini 10 flight (39897).

  3. Portrait of Gemini 11 prime and backup crews

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Portrait of Gemini 11 prime and backup crews. Seated are the Gemini 11 prime crewmembers (l.-r.) Astronauts Richard F. Gordon Jr., prime crew pilot, and Charles Conrad Jr., prime crew command pilot. Standing are (l.-r.) Astronauts William A. Anders, backup crew pilot, and Neil Armstrong, backup crew command pilot. They are in their space suits next to a mock-up of the Gemini spacecraft.

  4. Gemini 8 prime crew and other astronauts at prelaunch breakfast

    NASA Technical Reports Server (NTRS)

    1966-01-01

    The Gemini 8 prime crew, along with several fellow astronauts, have a hearty breakfast of steak and eggs on the morning of the Gemini 8 launch. Seated clockwise around the table, starting at lower left, are Donald K. Slayton, Manned Spaceflight Center (MSC) Assistant Director for Flight Crew Operations; Astronaut Neil A. Armstrong, Gemini 8 command pilot; Scientist-Astronaut F. Curtis Michel; Astronaut R. Walter Cunningham; Astronaut Alan B. Shepard Jr. (face obscured), Chief, MSC Astronaut Office; Astronaut David R. Scott, Gemini 8 pilot; and Astronaut Roger B. Chaffee.

  5. The Transformation of Observatory Newsletters - A Gemini Perspective

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaoyu

    2015-08-01

    Astronomical observatories publish newsletters to communicate the observatory’s new discoveries and activities with its user communities, funding agencies, and general public. Gemini Observatory started publishing the newsletter in March 1992. Over the years, it transformed from a no-frills black and white publication to a full-color magazine type newsletter with a special name “GeminiFocus”. Since 2012, the contents of GeminiFocus moved from print to digital with an additional print issue of the Year in Review. The newsletter transformation is in sync with the rapid development of the internet technologies. We discuss here the evolvement of Gemini newsletter and the lessons learned.

  6. Gemini planet imager integration to the Gemini South telescope software environment

    NASA Astrophysics Data System (ADS)

    Rantakyrö, Fredrik T.; Cardwell, Andrew; Chilcote, Jeffrey; Dunn, Jennifer; Goodsell, Stephen; Hibon, Pascale; Macintosh, Bruce; Quiroz, Carlos; Perrin, Marshall D.; Sadakuni, Naru; Saddlemyer, Leslie; Savransky, Dmitry; Serio, Andrew; Winge, Claudia; Galvez, Ramon; Gausachs, Gaston; Hardie, Kayla; Hartung, Markus; Luhrs, Javier; Poyneer, Lisa; Thomas, Sandrine

    2014-08-01

    The Gemini Planet Imager is an extreme AO instrument with an integral field spectrograph (IFS) operating in Y, J, H, and K bands. Both the Gemini telescope and the GPI instrument are very complex systems. Our goal is that the combined telescope and instrument system may be run by one observer operating the instrument, and one operator controlling the telescope and the acquisition of light to the instrument. This requires a smooth integration between the two systems and easily operated control interfaces. We discuss the definition of the software and hardware interfaces, their implementation and testing, and the integration of the instrument with the telescope environment.

  7. Solubilization of two organic dyes by cationic ester-containing gemini surfactants.

    PubMed

    Tehrani-Bagha, A R; Singh, R G; Holmberg, K

    2012-06-15

    Solubilization of two different types of organic dyes, Quinizarin with an anthraquinone structure and Sudan I with an azo structure, has been studied in aqueous solutions of a series of cationic gemini surfactants and of a conventional monomeric cationic surfactant, dodecyltrimethylammonium bromide (DTAB). Surfactant concentrations both above and below the critical micelle concentration were used. The concentration of solubilized dye at equilibrium was determined from the absorbance of the solution at λ(max) with the aid of a calibration curve. The solubilization power of the gemini surfactants was higher than that of DTAB and increased with increasing alkyl chain length. An increase in length of the spacer unit resulted in increased solubilization power while a hydroxyl group in the spacer did not have much effect. Ester bonds in the alkyl chains reduced the solubilization power with respect to both dyes. A comparison between the absorbance spectra of the dyes in micellar solution with spectra in a range of solvents of different polarity indicated that the dye is situated in a relatively polar environment. One may therefore assume that the dye is located just below the head group region of the micelle. Attractive π-cation interactions may play a role for orienting the dye to the outer region of the micelle.

  8. Interaction of a biosurfactant, Surfactin with a cationic Gemini surfactant in aqueous solution.

    PubMed

    Jin, Lei; Garamus, Vasil M; Liu, Fang; Xiao, Jingwen; Eckerlebe, Helmut; Willumeit-Römer, Regine; Mu, Bozhong; Zou, Aihua

    2016-11-01

    The interaction between biosurfactant Surfactin and cationic Gemini surfactant ethanediyl-1,3-bis(dodecyldimethylammonium bromide) (abbreviated as 12-3-12) was investigated using turbidity, surface tension, dynamic light scattering (DLS) and small angle neutron scattering (SANS). Analysis of critical micelle concentration (CMC) values in Surfactin/12-3-12 mixture indicates that there is synergism in formation of mixed Surfactin/12-3-12 micelles. Although Surfactin and 12-3-12 are oppositely charged in phosphate buffer solution (PBS, pH7.4), there are no precipitates observed at the concentrations below the CMC of Surfactin/12-3-12 system. However, at the concentration above CMC value, the Surfactin/12-3-12 mixture is severely turbid with high 12-3-12 content. DLS and SANS measurements follow the size and shape changes of mixed Surfactin/12-3-12 aggregates from small spherical micelles via elongated aggregates to large bulk complexes with increasing fraction of Gemini surfactant. PMID:27475707

  9. Mode changes associated with oil droplet movement in solutions of gemini cationic surfactants.

    PubMed

    Banno, Taisuke; Miura, Shingo; Kuroha, Rie; Toyota, Taro

    2013-06-25

    Micrometer-sized self-propelled oil droplets in nonequilibrium systems have attracted much attention, since they form stable emulsions composed of oil, water, and surfactant which represent a primitive type of inanimate chemical machinery. In this work, we examined means of controlling the movement of oil droplets by studying the dynamics of n-heptyloxybenzaldehyde droplets in phosphate buffers containing alkanediyl-α,ω-bis(N-dodecyl-N,N-dimethylammonium bromide) (nG12) with either tetramethylene (4G12), octaethylene (8G12), or dodecamethylene (12G12) chains in the linker moiety. Significant differences in droplet dynamics were observed to be induced by changes in the linker structure of these gemini cationic surfactants. In a phosphate buffer containing 30 mM 4G12, self-propelled motion of droplets concurrent with the formation of molecular aggregates on their surfaces was observed, whereas the fusion of oil droplets was evident in both 8G12 and 12G12 solutions. We also determined that the surface activities and the extent of molecular self-assembly of the surfactants in phosphate buffer were strongly influenced by the alkyl chain length in the linker moiety. We therefore conclude that the surface activities of the gemini cationic surfactant have important effects on the oil-water interfacial tension of oil droplets and the formation of molecular aggregates and that both of these factors induce the unique movement of the droplets.

  10. Monomeric and gemini surfactants as antimicrobial agents - influence on environmental and reference strains.

    PubMed

    Koziróg, Anna; Brycki, Bogumił

    2015-01-01

    Quaternary ammonium salts (QAS) belong to surfactant commonly used both, in the household and in different branches of industry, primarily in the process of cleaning and disinfection. They have several positive features inter alia effectively limiting the development of microorganisms on many surfaces. In the present work, two compounds were used as biocides: hexamethylene-1,6-bis-(N,N-dimethyl-N-dodecylammonium bromide) that belongs to the gemini surfactant (GS), and its single analogue - dodecyl(trimethyl)ammonium bromide (DTAB). Two fold dilution method was used to determine the minimum concentration of compounds (MIC) which inhibit the growth of bacteria: Staphylococcus aureus (ATCC 6538 and an environmental strain), Pseudomonas aeruginosa (ATCC 85327 and an environmental strain), and yeast Candida albicans (ATCC 11509 and an environmental strain). The viability of cells in liquid cultures with addition of these substances at ¼ MIC, ½ MIC and MIC concentrations were also determined. The obtained results show that DTAB inhibits the growth of bacteria at the concentration of 0.126-1.010 µM/ml, and gemini surfactant is active at 0.036-0.029 µM/ml. Therefore, GS is active at more than 17-70-fold lower concentrations than its monomeric analogue. Strains isolated from natural environment are less sensitive upon testing biocides than the references strains. Both compounds at the MIC value reduced the number of cells of all strains. The use of too low concentration of biocides can limit the growth of microorganisms, but often only for a short period of time in case of special environmental strains. Later on, they can adapt to adverse environmental conditions and begin to evolve defence mechanisms.

  11. Monomeric and gemini surfactants as antimicrobial agents - influence on environmental and reference strains.

    PubMed

    Koziróg, Anna; Brycki, Bogumił

    2015-01-01

    Quaternary ammonium salts (QAS) belong to surfactant commonly used both, in the household and in different branches of industry, primarily in the process of cleaning and disinfection. They have several positive features inter alia effectively limiting the development of microorganisms on many surfaces. In the present work, two compounds were used as biocides: hexamethylene-1,6-bis-(N,N-dimethyl-N-dodecylammonium bromide) that belongs to the gemini surfactant (GS), and its single analogue - dodecyl(trimethyl)ammonium bromide (DTAB). Two fold dilution method was used to determine the minimum concentration of compounds (MIC) which inhibit the growth of bacteria: Staphylococcus aureus (ATCC 6538 and an environmental strain), Pseudomonas aeruginosa (ATCC 85327 and an environmental strain), and yeast Candida albicans (ATCC 11509 and an environmental strain). The viability of cells in liquid cultures with addition of these substances at ¼ MIC, ½ MIC and MIC concentrations were also determined. The obtained results show that DTAB inhibits the growth of bacteria at the concentration of 0.126-1.010 µM/ml, and gemini surfactant is active at 0.036-0.029 µM/ml. Therefore, GS is active at more than 17-70-fold lower concentrations than its monomeric analogue. Strains isolated from natural environment are less sensitive upon testing biocides than the references strains. Both compounds at the MIC value reduced the number of cells of all strains. The use of too low concentration of biocides can limit the growth of microorganisms, but often only for a short period of time in case of special environmental strains. Later on, they can adapt to adverse environmental conditions and begin to evolve defence mechanisms. PMID:26641636

  12. Separation and determination of homologues of linear alkylbenzenesulfonates by nonaqueous capillary zone electrophoresis using alkylammonium salts in ethanol.

    PubMed

    Herrero-Martínez, J M; Simó-Alfonso, E F; Ramis-Ramos, G

    2001-06-01

    The separation of linear alkylbenzene sulfonates (LAS) by nonaqueous capillary electrophoresis (NACE) using negative polarity, and a buffer containing acetic acid and an alkylamine in nonaqueous ethanol, has been investigated. Several primary, secondary, and tertiary alkylamines with alkyl chains of different length were compared. The solutes travelled against the electroosmotic flow (EOF), and at the same time were braked by association with the alkylamine molecules or with the alkylammonium ions. The best resolution between adjacent LAS homologues (R approximately 2.1), partial isomer resolution in two peaks, and at the same time an excellent repeatability, was obtained with a small dipentylamine excess over the acetic acid. When the buffer concentration increased, resolution between the homologues increased slightly (R approximately 2.4), and a different isomer group was partially separated. A background electrolyte (BGE) containing 10 mM acetic acid and 20 mM dipentylamine to separate and quantify the homologues within 25 min is recommended. The isomer peak profile with up to three peaks can be estimated using this buffer and another one with 80 mM acetic acid and 90 mM dipentylamine. The former BGE was used to determine LAS in liquid and powder laundry detergents. The detection limit for the determination of total LAS in these products was 2.5 microg mL(-1), and the peak area and migration time interday repeatabilities were below 4.3 and 2.8%, respectively.

  13. Synthesis and characterization of a new family of alkylammonium-chromium phosphates with worm-like morphology

    NASA Astrophysics Data System (ADS)

    Amghouz, Zakariae; Espina, Aránzazu; García, José R.

    2015-01-01

    A series of layered alkylammonium-chromium phosphates, formulated as [CnH2n+1NH3]Cr(OH)PO4 (n=2-6), has been synthesized under hydrothermal conditions. The interlayer spacing, increasing linearly with the increase of alkyl-chain length from 13.61 Å (n=2) to 21.20 Å (n=6), is occupied by a double sheet of packed amine molecules with a tilt angle of ca. 51° respect to the inorganic sheet. The powders are constituted by circular plates (diameter=0.5-3 μm, thickness=~50 nm) with central holes when n=4-6, stacked in axial direction showing worm-like morphologies. The presence of holes, and some corrugated and zig-zag fashions observed on the edge of thin circular plates are the most probable ways for the reduction of the steric tensions between organic and inorganic portions in these hybrid materials. The thermal and thermo-oxidative stability of selected compounds have been studied, including the determination of activation energy data for the decomposition processes.

  14. Gemini Observatory's Innovative Education and Outreach for 2006 and Beyond

    NASA Astrophysics Data System (ADS)

    Harvey, J.

    2006-08-01

    Gemini Observatory, in preparation for its bold informal science plan for the next five years, is making an exciting effort to bring education outside our typical borders and into our partner countries and beyond. We will introduce some of the innovative outreach programs that have been highly successful in Hawaii/US and explain how Gemini's PIO efforts will further develop new concepts as we move forward in our next phase of education and outreach. In this presentation we will highlight a few of Gemini's highly successful initiatives: - Stars Over Mauna Kea Newspaper Tabloid, the second bi-annual publication giving a comprehensive review of astronomy on Mauna Kea - Hawaii's Journey through the Universe program which has been touted as the flagship program in the US. I will discuss how we envision introducing this novel education approach to our seven partner countries. - StarTeachers International teacher's exchange - The newly developed partnership between the Imiloa Astronomy Education Center's planetarium and Gemini's StarLab programs. - Extension of our Family Astro programs internationally. - Gemini's student "Time on the Telescope" mentor program. - "Gemini Live," a videoconference between our astronomers at the control room of Gemini and classrooms around the world. - The unique partnership created between Gemini's PIO department and the Department of Education in Hawaii, and how other astronomical facilities could play a prominent role in their state's/country's informal science education development.

  15. Current and future facility instruments at the Gemini Observatory

    NASA Astrophysics Data System (ADS)

    Jensen, Joseph B.; Kleinman, Scot J.; Simons, Douglas A.; Lazo, Manuel; Rigaut, François; White, John K.

    2008-07-01

    At the present time, several new Gemini instruments are being delivered and commissioned. The Near-Infrared Coronagraph has been extensively tested and commissioned on the Gemini-South telescope, and will soon begin a large survey to discover extrasolar planets. The FLAMINGOS-2 near-IR multi-object spectrograph is nearing completion at the University of Florida, and is expected to be delivered to Gemini-South by the end of 2008. Gemini's Multi-Conjugate Adaptive Optics bench has been successfully integrated and tested in the lab, and now awaits integration with the laser system and the Gemini-South AO Imager on the telescope. We also describe our efforts to repair thermal damage to the Gemini Near-IR Spectrograph that occurred last year. Since the last update, progress has been made on several of Gemini's next generation of ambitious "Aspen" instruments. The Gemini Planet Imager is now in the final design phase, and construction is scheduled to begin shortly. Two competitive conceptual design studies for the Wide-Field Fiber Multi-Object Spectrometer have now started. The Mauna Kea ground layer monitoring campaign has collected data for well over a year in support of the planning process for a future Ground Layer Adaptive Optics system.

  16. Portrait of the Gemini 8 prime and backup crews

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Portrait of the Gemini 8 prime and backup crews. Astronauts David R. Scott (left), pilot, and Astronaut Neil A. Armstrong, command pilot, are the prime crew of the Gemini 8 mission. Backup crew (left to right, standing), are Astronauts Richard F. Gordon Jr., pilot, and Charles Conrad Jr., command pilot.

  17. Gemini-IFU Spectroscopy of HH 111

    NASA Astrophysics Data System (ADS)

    Cerqueira, A. H.; Vasconcelos, M. J.; Raga, A. C.; Feitosa, J.; Plana, H.

    2015-03-01

    We present new optical observations of the Herbig-Haro (HH) 111 jet using the Gemini Multi Object Spectrograph in its Integral Field Unit mode. Eight fields of 5\\prime\\prime × 3\\buildrel{\\prime\\prime}\\over{.} 5 have been positioned along and across the HH 111 jet, covering the spatial region from knot E to L in HH 111 (namely, knots E, F, G, H, J, K, and L). We present images and velocity channel maps for the [O i] 6300+6360, Hα, [N ii] 6548+6583, and [S ii] 6716+6730 lines, as well as for the [S ii] 6716/6730 line ratio. We find that the HH 111 jet has an inner region with lower excitation and higher radial velocity, surrounded by a broader region of higher excitation and lower radial velocity. Also, we find higher electron densities at lower radial velocities. These results imply that the HH 111 jet has a fast, axial region with lower velocity shocks surrounded by a lower velocity sheath with higher velocity shocks. Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the Science and Technology Facilities Council (United Kingdom), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência, Tecnologia e Inovação (Brazil), and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina).

  18. Aggregation behaviors of gelatin with cationic gemini surfactant at air/water interface.

    PubMed

    Wu, Dan; Xu, Guiying; Feng, Yujun; Li, Yiming

    2007-03-10

    The dilational rheological properties of gelatin with cationic gemini surfactant 1,2-ethane bis(dimethyl dodecyl ammonium bromide) (C(12)C(2)C(12)) at air/water interface were investigated using oscillating barriers method at low frequency (0.005-0.1 Hz), which was compared with single-chain surfactant dodecyltrimethyl ammonium bromide (DTAB). The results indicate that the maximum dilational modulus and the film stability of gelatin-C(12)C(2)C(12) are higher than those of gelatin-DTAB. At high concentration of C(12)C(2)C(12) or DTAB, the dilational modulus of gelatin-surfactant system becomes close to that corresponding to pure surfactant, suggesting gelatin at interface is replaced by surfactant. This replacement is also observed by surface tension measurement. However, it is found that gelatin-C(12)C(2)C(12) system has two obvious breaks but gelatin-DTAB has not in surface tension isotherms. These phenomena are ascribed to the double charges and strong hydrophobicity of C(12)C(2)C(12). Based on these experimental results, a mechanism of gelatin-surfactant interaction at air/water interface is proposed.

  19. Self-Assembly of Gemini Surfactants

    NASA Astrophysics Data System (ADS)

    Yethiraj, Arun; Mondal, Jagannath; Mahanthappa, Mahesh

    2013-03-01

    The self-assembly behavior of Gemini (dimeric or twin-tail) dicarboxylate disodium surfactants is studied using molecular dynamics simulations. This gemini architecture, in which two single tailed surfactants are joined through a flexible hydrophobic linker, has been shown to exhibit concentration-dependent aqueous self-assembly into lyotropic phases including hexagonal, gyroid, and lamellar morphologies. Our simulations reproduce the experimentally observed phases at similar amphiphile concentrations in water, including the unusual ability of these surfactants to form gyroid phases over unprecedentedly large amphiphile concentration windows. We demonstrate quanitative agreement between the predicted and experimentally observed domain spacings of these nanostructured materials. Through careful conformation analyses of the surfactant molecules, we show that the gyroid phase is electrostatically stabilized related to the lamellar phase. By starting with a lamellar phase, we show that decreasing the charge on the surfactant headgroups by carboxylate protonation or use of a bulkier tetramethyl ammonium counterion in place of sodium drives the formation of a gyroid phase.

  20. First light of the Gemini Planet Imager

    DOE PAGES

    Macintosh, Bruce; Graham, James R.; Ingraham, Patrick; Konopacky, Quinn; Marois, Christian; Perrin, Marshall; Poyneer, Lisa; Bauman, Brian; Barman, Travis; Burrows, Adam S.; et al

    2014-05-12

    The Gemini Planet Imager is a dedicated facility for directly imaging and spectroscopically characterizing extrasolar planets. It combines a very high-order adaptive optics system, a diffraction-suppressing coronagraph, and an integral field spectrograph with low spectral resolution but high spatial resolution. Every aspect of the Gemini Planet Imager has been tuned for maximum sensitivity to faint planets near bright stars. During first-light observations, we achieved an estimated H band Strehl ratio of 0.89 and a 5-σ contrast of 106 at 0.75 arcseconds and 105 at 0.35 arcseconds. Observations of Beta Pictoris clearly detect the planet, Beta Pictoris b, in a singlemore » 60-s exposure with minimal postprocessing. Beta Pictoris b is observed at a separation of 434 ± 6 milliarcseconds (mas) and position angle 211.8 ± 0.5°. Fitting the Keplerian orbit of Beta Pic b using the new position together with previous astrometry gives a factor of 3 improvement in most parameters over previous solutions. The planet orbits at a semimajor axis of 9.0+0.8–0.4 AU near the 3:2 resonance with the previously known 6-AU asteroidal belt and is aligned with the inner warped disk. In conclusion, the observations give a 4% probability of a transit of the planet in late 2017.« less

  1. First light of the Gemini Planet Imager

    PubMed Central

    Macintosh, Bruce; Graham, James R.; Ingraham, Patrick; Konopacky, Quinn; Marois, Christian; Perrin, Marshall; Poyneer, Lisa; Bauman, Brian; Barman, Travis; Burrows, Adam S.; Cardwell, Andrew; Chilcote, Jeffrey; De Rosa, Robert J.; Dillon, Daren; Doyon, Rene; Dunn, Jennifer; Erikson, Darren; Fitzgerald, Michael P.; Gavel, Donald; Goodsell, Stephen; Hartung, Markus; Hibon, Pascale; Kalas, Paul; Larkin, James; Maire, Jerome; Marchis, Franck; Marley, Mark S.; McBride, James; Millar-Blanchaer, Max; Morzinski, Katie; Norton, Andrew; Oppenheimer, B. R.; Palmer, David; Patience, Jennifer; Pueyo, Laurent; Rantakyro, Fredrik; Sadakuni, Naru; Saddlemyer, Leslie; Savransky, Dmitry; Serio, Andrew; Soummer, Remi; Sivaramakrishnan, Anand; Song, Inseok; Thomas, Sandrine; Wallace, J. Kent; Wiktorowicz, Sloane; Wolff, Schuyler

    2014-01-01

    The Gemini Planet Imager is a dedicated facility for directly imaging and spectroscopically characterizing extrasolar planets. It combines a very high-order adaptive optics system, a diffraction-suppressing coronagraph, and an integral field spectrograph with low spectral resolution but high spatial resolution. Every aspect of the Gemini Planet Imager has been tuned for maximum sensitivity to faint planets near bright stars. During first-light observations, we achieved an estimated H band Strehl ratio of 0.89 and a 5-σ contrast of 106 at 0.75 arcseconds and 105 at 0.35 arcseconds. Observations of Beta Pictoris clearly detect the planet, Beta Pictoris b, in a single 60-s exposure with minimal postprocessing. Beta Pictoris b is observed at a separation of 434 ± 6 milliarcseconds (mas) and position angle 211.8 ± 0.5°. Fitting the Keplerian orbit of Beta Pic b using the new position together with previous astrometry gives a factor of 3 improvement in most parameters over previous solutions. The planet orbits at a semimajor axis of 9.0−0.4+0.8 AU near the 3:2 resonance with the previously known 6-AU asteroidal belt and is aligned with the inner warped disk. The observations give a 4% probability of a transit of the planet in late 2017. PMID:24821792

  2. Tumbling and spaceflight: the Gemini VIII experience.

    PubMed

    Mohler, S R; Nicogossian, A E; McCormack, P D; Mohler, S R

    1990-01-01

    A malfunctioning orbital flight attitude thruster during the flight of Gemini VIII led to acceleration forces on astronauts Neil Armstrong (commander) and David Scott (pilot) that created the potential for derogation of oculo-vestibular and eye-hand coordination effects. The spacecraft attained an axial tumbling rotation of 50 rpm and would have exceeded this had not the commander accurately diagnosed the problem and taken immediate corrective action. By the time counter-measure controls were applied, both astronauts were experiencing vertigo and the physiological effects of the tumbling acceleration. Data from the recorders reveal that one astronaut experienced -Gy of 0.92 G-units, and the other +Gy of 0.92 for approximately 46 s. Both received a -Gz of 0.89 G-units from the waist up with a +Gz of 0.05 from the waist down. A substantial increase of time and/or an increase in rpm would ultimately have produced incapacitation of both astronauts. NASA corrected the Gemini thruster problem by changing the ignition system wiring. Future space-craft undertaking long-term missions could be equipped with unambiguous thruster fault displays and could have computer-controlled automatic cutoffs to control excessive thruster burns. PMID:2302130

  3. First light of the Gemini Planet imager.

    PubMed

    Macintosh, Bruce; Graham, James R; Ingraham, Patrick; Konopacky, Quinn; Marois, Christian; Perrin, Marshall; Poyneer, Lisa; Bauman, Brian; Barman, Travis; Burrows, Adam S; Cardwell, Andrew; Chilcote, Jeffrey; De Rosa, Robert J; Dillon, Daren; Doyon, Rene; Dunn, Jennifer; Erikson, Darren; Fitzgerald, Michael P; Gavel, Donald; Goodsell, Stephen; Hartung, Markus; Hibon, Pascale; Kalas, Paul; Larkin, James; Maire, Jerome; Marchis, Franck; Marley, Mark S; McBride, James; Millar-Blanchaer, Max; Morzinski, Katie; Norton, Andrew; Oppenheimer, B R; Palmer, David; Patience, Jennifer; Pueyo, Laurent; Rantakyro, Fredrik; Sadakuni, Naru; Saddlemyer, Leslie; Savransky, Dmitry; Serio, Andrew; Soummer, Remi; Sivaramakrishnan, Anand; Song, Inseok; Thomas, Sandrine; Wallace, J Kent; Wiktorowicz, Sloane; Wolff, Schuyler

    2014-09-01

    The Gemini Planet Imager is a dedicated facility for directly imaging and spectroscopically characterizing extrasolar planets. It combines a very high-order adaptive optics system, a diffraction-suppressing coronagraph, and an integral field spectrograph with low spectral resolution but high spatial resolution. Every aspect of the Gemini Planet Imager has been tuned for maximum sensitivity to faint planets near bright stars. During first-light observations, we achieved an estimated H band Strehl ratio of 0.89 and a 5-σ contrast of 10(6) at 0.75 arcseconds and 10(5) at 0.35 arcseconds. Observations of Beta Pictoris clearly detect the planet, Beta Pictoris b, in a single 60-s exposure with minimal postprocessing. Beta Pictoris b is observed at a separation of 434 ± 6 milliarcseconds (mas) and position angle 211.8 ± 0.5°. Fitting the Keplerian orbit of Beta Pic b using the new position together with previous astrometry gives a factor of 3 improvement in most parameters over previous solutions. The planet orbits at a semimajor axis of [Formula: see text] near the 3:2 resonance with the previously known 6-AU asteroidal belt and is aligned with the inner warped disk. The observations give a 4% probability of a transit of the planet in late 2017. PMID:24821792

  4. First light of the Gemini Planet imager.

    PubMed

    Macintosh, Bruce; Graham, James R; Ingraham, Patrick; Konopacky, Quinn; Marois, Christian; Perrin, Marshall; Poyneer, Lisa; Bauman, Brian; Barman, Travis; Burrows, Adam S; Cardwell, Andrew; Chilcote, Jeffrey; De Rosa, Robert J; Dillon, Daren; Doyon, Rene; Dunn, Jennifer; Erikson, Darren; Fitzgerald, Michael P; Gavel, Donald; Goodsell, Stephen; Hartung, Markus; Hibon, Pascale; Kalas, Paul; Larkin, James; Maire, Jerome; Marchis, Franck; Marley, Mark S; McBride, James; Millar-Blanchaer, Max; Morzinski, Katie; Norton, Andrew; Oppenheimer, B R; Palmer, David; Patience, Jennifer; Pueyo, Laurent; Rantakyro, Fredrik; Sadakuni, Naru; Saddlemyer, Leslie; Savransky, Dmitry; Serio, Andrew; Soummer, Remi; Sivaramakrishnan, Anand; Song, Inseok; Thomas, Sandrine; Wallace, J Kent; Wiktorowicz, Sloane; Wolff, Schuyler

    2014-09-01

    The Gemini Planet Imager is a dedicated facility for directly imaging and spectroscopically characterizing extrasolar planets. It combines a very high-order adaptive optics system, a diffraction-suppressing coronagraph, and an integral field spectrograph with low spectral resolution but high spatial resolution. Every aspect of the Gemini Planet Imager has been tuned for maximum sensitivity to faint planets near bright stars. During first-light observations, we achieved an estimated H band Strehl ratio of 0.89 and a 5-σ contrast of 10(6) at 0.75 arcseconds and 10(5) at 0.35 arcseconds. Observations of Beta Pictoris clearly detect the planet, Beta Pictoris b, in a single 60-s exposure with minimal postprocessing. Beta Pictoris b is observed at a separation of 434 ± 6 milliarcseconds (mas) and position angle 211.8 ± 0.5°. Fitting the Keplerian orbit of Beta Pic b using the new position together with previous astrometry gives a factor of 3 improvement in most parameters over previous solutions. The planet orbits at a semimajor axis of [Formula: see text] near the 3:2 resonance with the previously known 6-AU asteroidal belt and is aligned with the inner warped disk. The observations give a 4% probability of a transit of the planet in late 2017.

  5. First light of the Gemini Planet Imager

    SciTech Connect

    Macintosh, Bruce; Graham, James R.; Ingraham, Patrick; Konopacky, Quinn; Marois, Christian; Perrin, Marshall; Poyneer, Lisa; Bauman, Brian; Barman, Travis; Burrows, Adam S.; Cardwell, Andrew; Chilcote, Jeffrey; De Rosa, Robert J.; Dillon, Daren; Doyon, Rene; Dunn, Jennifer; Erikson, Darren; Fitzgerald, Michael P.; Gavel, Donald; Goodsell, Stephen; Hartung, Markus; Hibon, Pascale; Kalas, Paul; Larkin, James; Maire, Jerome; Marchis, Franck; Marley, Mark S.; McBride, James; Millar-Blanchaer, Max; Morzinski, Katie; Norton, Andrew; Oppenheimer, B. R.; Palmer, David; Patience, Jennifer; Pueyo, Laurent; Rantakyro, Fredrik; Sadakuni, Naru; Saddlemyer, Leslie; Savransky, Dmitry; Serio, Andrew; Soummer, Remi; Sivaramakrishnan, Anand; Song, Inseok; Thomas, Sandrine; Wallace, J. Kent; Wiktorowicz, Stone; Wolff, Schuyler

    2014-05-12

    The Gemini Planet Imager is a dedicated facility for directly imaging and spectroscopically characterizing extrasolar planets. It combines a very high-order adaptive optics system, a diffraction-suppressing coronagraph, and an integral field spectrograph with low spectral resolution but high spatial resolution. Every aspect of the Gemini Planet Imager has been tuned for maximum sensitivity to faint planets near bright stars. During first-light observations, we achieved an estimated H band Strehl ratio of 0.89 and a 5-σ contrast of 106 at 0.75 arcseconds and 105 at 0.35 arcseconds. Observations of Beta Pictoris clearly detect the planet, Beta Pictoris b, in a single 60-s exposure with minimal postprocessing. Beta Pictoris b is observed at a separation of 434 ± 6 milliarcseconds (mas) and position angle 211.8 ± 0.5°. Fitting the Keplerian orbit of Beta Pic b using the new position together with previous astrometry gives a factor of 3 improvement in most parameters over previous solutions. The planet orbits at a semimajor axis of 9.0+0.8–0.4 AU near the 3:2 resonance with the previously known 6-AU asteroidal belt and is aligned with the inner warped disk. In conclusion, the observations give a 4% probability of a transit of the planet in late 2017.

  6. Tumbling and spaceflight: the Gemini VIII experience.

    PubMed

    Mohler, S R; Nicogossian, A E; McCormack, P D; Mohler, S R

    1990-01-01

    A malfunctioning orbital flight attitude thruster during the flight of Gemini VIII led to acceleration forces on astronauts Neil Armstrong (commander) and David Scott (pilot) that created the potential for derogation of oculo-vestibular and eye-hand coordination effects. The spacecraft attained an axial tumbling rotation of 50 rpm and would have exceeded this had not the commander accurately diagnosed the problem and taken immediate corrective action. By the time counter-measure controls were applied, both astronauts were experiencing vertigo and the physiological effects of the tumbling acceleration. Data from the recorders reveal that one astronaut experienced -Gy of 0.92 G-units, and the other +Gy of 0.92 for approximately 46 s. Both received a -Gz of 0.89 G-units from the waist up with a +Gz of 0.05 from the waist down. A substantial increase of time and/or an increase in rpm would ultimately have produced incapacitation of both astronauts. NASA corrected the Gemini thruster problem by changing the ignition system wiring. Future space-craft undertaking long-term missions could be equipped with unambiguous thruster fault displays and could have computer-controlled automatic cutoffs to control excessive thruster burns.

  7. The effect of the spacer rigidity on the aggregation behavior of two ester-containing Gemini surfactants.

    PubMed

    Zhang, Zhiguo; Zheng, Peizhu; Guo, Yimin; Yang, Yan; Chen, Zhiyun; Wang, Xiaoyong; An, Xueqin; Shen, Weiguo

    2012-08-01

    Two Gemini surfactants with very similar structure but different spacer rigidity, namely 1-dodecanaminium,N,N'-[[(2E)-1,4-dioxo-2-butene-1,4-diyl]bis(oxy-2,1-ethanediyl)]bis[N,N-dimethyl-,bromide] (12-fo-12) and 1-dodecanaminium, N,N'-[(1,4-dioxo-1,4-butanediyl)bis(oxy-2,1-ethanediyl)] bis[N,N-dimethyl-, bromide] (12-su-12), and their monomeric counterpart 1-dodecanaminium, N-[2-(acetyloxy)ethyl]-N,N-dimethyl-, bromide (DTAAB) were synthesized and their aggregation behavior in aqueous solutions was studied by measurements of surface tension, conductivity, isothermal titration calorimetry, dynamic light scattering, and transmission electron microscopy. It was found that the Krafft point of 12-fo-12 was 18.6°C, significantly higher than that of 12-su-12 (7.6°C) and DTAAB (<0°C). The minimum surface areas per surfactant A(min) at the water-air interface of DTAAB, 12-su-12, and 12-fo-12 were determined. It was found that the value of A(min) of DTAAB was larger than half that of 12-su-12 but smaller than half that of 12-fo-12. The values of the degree of association β of the three surfactants were found to be in a sequence of DTAAB>12-su-12>12-fo-12, which was in accord with the sequence of the entropy of micellization. The enthalpies of micellization of the two Gemini surfactants were found to be more negative than double that of DTAAB, and 12-fo-12 had the most negative standard enthalpy of micellization. It was also found that 12-su-12 and DTAAB formed micelles in aqueous solutions, while 12-fo-12 could form micelles and vesicles dependent on the concentration.

  8. Different sensitivities of rat skeletal muscles and brain to novel anti-cholinesterase agents, alkylammonium derivatives of 6-methyluracil (ADEMS)

    PubMed Central

    Petrov, Konstantin A; Yagodina, Lilia O; Valeeva, Guzel R; Lannik, Natalya I; Nikitashina, Alexandra D; Rizvanov, Albert A; Zobov, Vladimir V; Bukharaeva, Ellya A; Reznik, Vladimir S; Nikolsky, Eugeny E; Vyskočil, František

    2011-01-01

    BACKGROUND AND PURPOSE The rat respiratory muscle diaphragm has markedly lower sensitivity than the locomotor muscle extensor digitorum longus (EDL) to the new acetylcholinesterase (AChE) inhibitors, alkylammonium derivatives of 6-methyluracil (ADEMS). This study evaluated several possible reasons for differing sensitivity between the diaphragm and limb muscles and between the muscles and the brain. EXPERIMENTAL APPROACH Increased amplitude and prolonged decay time of miniature endplate currents were used to assess anti-cholinesterase activity in muscles. In hippocampal slices, induction of synchronous network activity was used to follow cholinesterase inhibition. The inhibitor sensitivities of purified AChE from the EDL and brain were also estimated. KEY RESULTS The intermuscular difference in sensitivity to ADEMS is partly explained caused by a higher level of mRNA and activity of 1,3-bis[5(diethyl-o-nitrobenzylammonium)pentyl]-6-methyluracildibromide (C-547)-resistant BuChE in the diaphragm. Moreover, diaphragm AChE was more than 20 times less sensitive to C-547 than that from the EDL. Sensitivity of the EDL to C-547 dramatically decreased after treadmill exercises that increased the amount of PRiMA AChE(G4), but not ColQ AChE(A12) molecular forms. The A12 form present in muscles appeared more sensitive to C-547. The main form of AChE in brain, PRiMA AChE(G4), was apparently less sensitive because brain cholinesterase activity was almost three orders of magnitude more resistant to C-547 than that of the EDL. CONCLUSIONS AND IMPLICATIONS Our findings suggest that ADEMS compounds could be used for the selective inhibition of AChEs and as potential therapeutic tools. PMID:21232040

  9. Geo-Engineering through Internet Informatics (GEMINI)

    SciTech Connect

    Watney, W. Lynn; Doveton, John H.; Victorine, John R.; Bohling, Goeffrey C.; Bhattacharya, Saibal; Byers, Alan P.; Carr, Timothy R.; Dubois, Martin K.; Gagnon, Glen; Guy, Willard J.; Look, Kurt; Magnuson, Mike; Moore, Melissa; Olea, Ricardo; Pakalapadi, Jayprakash; Stalder, Ken; Collins, David R.

    2002-06-25

    GEMINI will resolve reservoir parameters that control well performance; characterize subtle reservoir properties important in understanding and modeling hydrocarbon pore volume and fluid flow; expedite recognition of bypassed, subtle, and complex oil and gas reservoirs at regional and local scale; differentiate commingled reservoirs; build integrated geologic and engineering model based on real-time, iterate solutions to evaluate reservoir management options for improved recovery; provide practical tools to assist the geoscientist, engineer, and petroleum operator in making their tasks more efficient and effective; enable evaluations to be made at different scales, ranging from individual well, through lease, field, to play and region (scalable information infrastructure); and provide training and technology transfer to evaluate capabilities of the client.

  10. The Gemini Planet Imager: integration and status

    NASA Astrophysics Data System (ADS)

    Macintosh, Bruce A.; Anthony, Andre; Atwood, Jennifer; Barriga, Nicolas; Bauman, Brian; Caputa, Kris; Chilcote, Jeffery; Dillon, Daren; Doyon, René; Dunn, Jennifer; Gavel, Donald T.; Galvez, Ramon; Goodsell, Stephen J.; Graham, James R.; Hartung, Markus; Isaacs, Joshua; Kerley, Dan; Konopacky, Quinn; Labrie, Kathleen; Larkin, James E.; Maire, Jerome; Marois, Christian; Millar-Blanchaer, Max; Nunez, Arturo; Oppenheimer, Ben R.; Palmer, David W.; Pazder, John; Perrin, Marshall; Poyneer, Lisa A.; Quirez, Carlos; Rantakyro, Frederik; Reshtov, Vlad; Saddlemyer, Leslie; Sadakuni, Naru; Savransky, Dmitry; Sivaramakrishnan, Anand; Smith, Malcolm; Soummer, Remi; Thomas, Sandrine; Wallace, J. Kent; Weiss, Jason; Wiktorowicz, Sloane

    2012-09-01

    The Gemini Planet Imager is a next-generation instrument for the direct detection and characterization of young warm exoplanets, designed to be an order of magnitude more sensitive than existing facilities. It combines a 1700-actuator adaptive optics system, an apodized-pupil Lyot coronagraph, a precision interferometric infrared wavefront sensor, and a integral field spectrograph. All hardware and software subsystems are now complete and undergoing integration and test at UC Santa Cruz. We will present test results on each subsystem and the results of end-to-end testing. In laboratory testing, GPI has achieved a raw contrast (without post-processing) of 10-6 5σ at 0.4", and with multiwavelength speckle suppression, 2x10-7 at the same separation.

  11. Gemini: A long-range cargo transport

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The proposed Gemini, a long-range cargo transport, is designed as a high capacity, dedicated cargo transporter of 8'x8'x20' inter-modal containers, and long-range design. These requirements will result in a design that is larger than any existing aircraft. Due to the size, a conventional configuration would result in an aircraft unable to operate economically at existing airports. It is necessary to design for a minimum possible empty weight, wingspan, and landing gear track. After considering both a single fuselage biplane and a double fuselage biplane configuration, the design team choose the double fuselage biplane configuration. Both of these configuration choices result in a reduced wing root bending moment and subsequently in substantial savings in the wing weight. An overall decrease in the weight of the airplane, its systems, and fuel will be a direct result of the wing weight savings.

  12. Wavefront control for the Gemini Planet Imager

    SciTech Connect

    Poyneer, L A; Veran, J; Dillon, D; Severson, S; Macintosh, B

    2006-04-14

    The wavefront control strategy for the proposed Gemini Planet Imager, an extreme adaptive optics coronagraph for planet detection, is presented. Two key parts of this strategy are experimentally verified in a testbed at the Laboratory for Adaptive Optics, which features a 32 x 32 MEMS device. Detailed analytic models and algorithms for Shack-Hartmann wavefront sensor alignment and calibration are presented. It is demonstrated that with these procedures, the spatially filtered WFS and the Fourier Transform reconstructor can be used to flatten to the MEMS to 1 nm RMS in the controllable band. Performance is further improved using the technique of modifying the reference slopes using a measurement of the static wavefront error in the science leg.

  13. The Gemini Planet Imager Exoplanet Survey

    NASA Astrophysics Data System (ADS)

    Macintosh, Bruce

    The Gemini Planet Imager (GPI) is a next-generation coronagraph constructed for the Gemini Observatory. GPI will see first light this fall. It will be the most advanced planet-imaging system in operation - an order of magnitude more sensitive than any current instrument, capable of detecting and spectroscopically characterizing young Jovian planets 107 times fainter than their parent star at separations of 0.2 arcseconds. GPI was built from the beginning as a facility-class survey instrument, and the observatory will employ it that way. Our team has been selected by Gemini Observatory to carry out an 890-hour program - the GPI Exoplanet Survey (GPIES) campaign from 2014-2017. We will observe 600 stars spanning spectral types A-M. We will use published young association catalogs and a proprietary list in preparation that adds several hundred new young (<100 Myr, <75 pc) and adolescent (<300 Myr, <35 pc) stars. The range of separations studied by GPI is completely inaccessible to Doppler and transit techniques (even with Kepler or TESS)— GPI offers a new window into planet formation. We will use GPI to produce the first-ever robust census of giant planet populations in the 5-50 AU range, allowing us to: 1) illuminate the formation pathways of Jovian planets; 2) reconstruct the early dynamical evolution of systems, including migration mechanisms and the interaction with disks and belts of debris; and 3) bridge the gap between Jupiter and the brown dwarfs with the first examples of cool low- gravity planetary atmospheres. Simulations predict this survey will discover approximately 50 exoplanets, increasing the number of exoplanet images by an order of magnitude, enough for statistical investigation. This Origins of Solar Systems proposal will support the execution of the GPI Exoplanet Survey campaign. We will develop tools needed to execute the survey efficiently. We will refine the existing GPI data pipeline to a final version that robustly removes residual speckle

  14. First light of the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Macintosh, Bruce; Graham, James R.; Ingraham, Patrick; Konopacky, Quinn; Marois, Christian; Perrin, Marshall; Poyneer, Lisa; Bauman, Brian; Barman, Travis; Burrows, Adam S.; Cardwell, Andrew; Chilcote, Jeffrey; De Rosa, Robert J.; Dillon, Daren; Doyon, Rene; Dunn, Jennifer; Erikson, Darren; Fitzgerald, Michael P.; Gavel, Donald; Goodsell, Stephen; Hartung, Markus; Hibon, Pascale; Kalas, Paul; Larkin, James; Maire, Jerome; Marchis, Franck; Marley, Mark S.; McBride, James; Millar-Blanchaer, Max; Morzinski, Katie; Norton, Andrew; Oppenheimer, B. R.; Palmer, David; Patience, Jennifer; Pueyo, Laurent; Rantakyro, Fredrik; Sadakuni, Naru; Saddlemyer, Leslie; Savransky, Dmitry; Serio, Andrew; Soummer, Remi; Sivaramakrishnan, Anand; Song, Inseok; Thomas, Sandrine; Wallace, J. Kent; Wiktorowicz, Sloane; Wolff, Schuyler

    2014-09-01

    The Gemini Planet Imager is a dedicated facility for directly imaging and spectroscopically characterizing extrasolar planets. It combines a very high-order adaptive optics system, a diffraction-suppressing coronagraph, and an integral field spectrograph with low spectral resolution but high spatial resolution. Every aspect of the Gemini Planet Imager has been tuned for maximum sensitivity to faint planets near bright stars. During first-light observations, we achieved an estimated H band Strehl ratio of 0.89 and a 5-σ contrast of 106 at 0.75 arcseconds and 105 at 0.35 arcseconds. Observations of Beta Pictoris clearly detect the planet, Beta Pictoris b, in a single 60-s exposure with minimal postprocessing. Beta Pictoris b is observed at a separation of 434 ± 6 milliarcseconds (mas) and position angle 211.8 ± 0.5°. Fitting the Keplerian orbit of Beta Pic b using the new position together with previous astrometry gives a factor of 3 improvement in most parameters over previous solutions. The planet orbits at a semimajor axis of 9.0-0.4+0.8AU near the 3:2 resonance with the previously known 6-AU asteroidal belt and is aligned with the inner warped disk. The observations give a 4% probability of a transit of the planet in late 2017.

  15. Structural Characterization of Novel Gemini Non-viral DNA

    SciTech Connect

    Foldvari,M.; Badea, I.; Wettig, S.; Verrall, R.; Bagonluri, M.

    2006-01-01

    The structural and physicochemical properties of novel cationic lipid-based DNA complexes have been investigated for the purpose of designing micro/nano-scale self-assembling delivery systems for cutaneous gene therapy. DNA/gemini surfactant (spacer n = 3-16; chain m = 12 or 16) complexes (1 : 10 charge ratio), with or without dioleoylphosphatidyl-ethanolamine (DOPE), designed for cellular transfection, were generally in the range of 100-200 nm as demonstrated by atomic force microscopy and particle size analysis. Small-angle X-ray scattering measurements indicated that the DNA/gemini complexes lacked long-range order, whereas DNA/gemini/DOPE complexes exhibited lamellar and polymorphic phases other than hexagonal. Correlation studies using transfection efficiency data in PAM 212 keratinocytes and in vitro skin absorption indicated that formulations containing gemini surfactants having the ability to induce structures other than lamellar in the resulting complexes, generally exhibited greater transfection activity and cutaneous absorption.

  16. Food packages for use on the Gemini 4 flight

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Food packages for use on the Gemini 4 flight. Packages include beef and gravy, peaches, strawberry cereal cubes and beef sandwiches. Water gun is used to reconstitute dehydrated food. Scissors are used to open the packages.

  17. Indonesian Islands as seen from Gemini 11 spacecraft

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Indonesian Islands (partial cloud cover): Sumatra, Java, Bali, Borneo, Sumbawa, as photographed from the Gemini 11 spacecraft during its 26th revolution of the earth, at an altitude of 570 nautical miles.

  18. View of Gemini 11 experiment S-13 Ultraviolet Astronomical Camera

    NASA Technical Reports Server (NTRS)

    1966-01-01

    View of Gemini 11 experiment S-13 Ultraviolet Astronomical Camera before flight. Its object was to obtain data on ultraviolet radiation of hot stars and to develop and evaluate basic techniques for photography of celestial objects from manned spacecraft.

  19. Lanthanum Bromide Detectors for Safeguards Measurements

    SciTech Connect

    Wright, J.

    2011-05-25

    Lanthanum bromide has advantages over other popular inorganic scintillator detectors. Lanthanum bromide offers superior resolution, and good efficiency when compared to sodium iodide and lanthanum chloride. It is a good alternative to high purity germanium detectors for some safeguards applications. This paper offers an initial look at lanthanum bromide detectors. Resolution of lanthanum bromide will be compared lanthanum chloride and sodium-iodide detectors through check source measurements. Relative efficiency and angular dependence will be looked at. Nuclear material spectra, to include plutonium and highly enriched uranium, will be compared between detector types.

  20. New serine-derived gemini surfactants as gene delivery systems.

    PubMed

    Cardoso, Ana M; Morais, Catarina M; Cruz, A Rita; Silva, Sandra G; do Vale, M Luísa; Marques, Eduardo F; de Lima, Maria C Pedroso; Jurado, Amália S

    2015-01-01

    Gemini surfactants have been extensively used for in vitro gene delivery. Amino acid-derived gemini surfactants combine the special aggregation properties characteristic of the gemini surfactants with high biocompatibility and biodegradability. In this work, novel serine-derived gemini surfactants, differing in alkyl chain lengths and in the linker group bridging the spacer to the headgroups (amine, amide and ester), were evaluated for their ability to mediate gene delivery either per se or in combination with helper lipids. Gemini surfactant-based DNA complexes were characterized in terms of hydrodynamic diameter, surface charge, stability in aqueous buffer and ability to protect DNA. Efficient formulations, able to transfect up to 50% of the cells without causing toxicity, were found at very low surfactant/DNA charge ratios (1/1-2/1). The most efficient complexes presented sizes suitable for intravenous administration and negative surface charge, a feature known to preclude potentially adverse interactions with serum components. This work brings forward a new family of gemini surfactants with great potential as gene delivery systems.

  1. GEMINI: Integrative Exploration of Genetic Variation and Genome Annotations

    PubMed Central

    Paila, Umadevi; Chapman, Brad A.; Kirchner, Rory; Quinlan, Aaron R.

    2013-01-01

    Modern DNA sequencing technologies enable geneticists to rapidly identify genetic variation among many human genomes. However, isolating the minority of variants underlying disease remains an important, yet formidable challenge for medical genetics. We have developed GEMINI (GEnome MINIng), a flexible software package for exploring all forms of human genetic variation. Unlike existing tools, GEMINI integrates genetic variation with a diverse and adaptable set of genome annotations (e.g., dbSNP, ENCODE, UCSC, ClinVar, KEGG) into a unified database to facilitate interpretation and data exploration. Whereas other methods provide an inflexible set of variant filters or prioritization methods, GEMINI allows researchers to compose complex queries based on sample genotypes, inheritance patterns, and both pre-installed and custom genome annotations. GEMINI also provides methods for ad hoc queries and data exploration, a simple programming interface for custom analyses that leverage the underlying database, and both command line and graphical tools for common analyses. We demonstrate GEMINI's utility for exploring variation in personal genomes and family based genetic studies, and illustrate its ability to scale to studies involving thousands of human samples. GEMINI is designed for reproducibility and flexibility and our goal is to provide researchers with a standard framework for medical genomics. PMID:23874191

  2. Effects of spacer chain length of amino acid-based gemini surfactants on wormlike micelle formation.

    PubMed

    Sakai, Kenichi; Nomura, Kazuyuki; Shrestha, Rekha Goswami; Endo, Takeshi; Sakamoto, Kazutami; Sakai, Hideki; Abe, Masahiko

    2014-01-01

    We studied the effects of the spacer chain length of amino acid-based gemini surfactants on the formation of wormlike micelles in aqueous solutions. The surfactants used were synthesized by reacting dodecanoylglutamic acid anhydride with diamine compounds (ethylenediamine, pentanediamine, and octanediamine), and were abbreviated as 12-GsG-12 (s: the spacer chain length of 2, 5, and 8 methylene units). These surfactants yielded viscoelastic wormlike micellar solutions at pH 9 upon mixing with a cationic monomeric surfactant, hexadecyltrimethylammonium bromide (HTAB). We found that the rheological behavior was strongly dependent on the spacer chain length and HTAB concentration. When the shortest spacer chain analogue (12-G2G-12) was used, an increased HTAB concentration resulted in the following structural transformations of the micelles: (i) spherical or rodlike micelles; (ii) anionic wormlike micelles exhibiting a transient network structure; (iii) anionic wormlike micelles with a micellar branching or interconnected structure; and (iv) cationic wormlike micelles. Similarly, when the middle spacer chain analogue (12-G5G-12) was used, a structural transformation from anionic to cationic wormlike micelles occurs; however, molecular aggregates with a lower positive curvature were also formed in this transition region. When the longest spacer analogue (12-G8G-12) was used, the formation of cation-rich molecular aggregates was not observed. These transition behaviors were attributed to the packing geometry of the gemini surfactants with HTAB. Additionally, as the spacer chain length increased, the zero-shear viscosity in the anionic wormlike micellar region decreased, suggesting limited one-dimensional micellar growth of spherical, rodlike, or anionic wormlike micelles.

  3. The Gemini Deep Planet Survey - GDPS

    SciTech Connect

    Lafreniere, D; Doyon, R; Marois, C; Nadeau, D; Oppenheimer, B R; Roche, P F; Rigaut, F; Graham, J R; Jayawardhana, R; Johnstone, D; Kalas, P G; Macintosh, B; Racine, R

    2007-06-01

    We present the results of the Gemini Deep Planet Survey, a near-infrared adaptive optics search for giant planets and brown dwarfs around nearby young stars. The observations were obtained with the Altair adaptive optics system at the Gemini North telescope and angular differential imaging was used to suppress the speckle noise of the central star. Detection limits for the 85 stars observed are presented, along with a list of all faint point sources detected around them. Typically, the observations are sensitive to angular separations beyond 0.5-inch with 5{sigma} contrast sensitivities in magnitude difference at 1.6 {micro}m of 9.6 at 0.5-inch, 12.9 at 1-inch, 15 at 2-inch, and 16.6 at 5-inch. For the typical target of the survey, a 100 Myr old K0 star located 22 pc from the Sun, the observations are sensitive enough to detect planets more massive than 2 M{sub Jup} with a projected separation in the range 40-200 AU. Depending on the age, spectral type, and distance of the target stars, the minimum mass that could be detected with our observations can be {approx}1 M{sub Jup}. Second epoch observations of 48 stars with candidates (out of 54) have confirmed that all candidates are unrelated background stars. A detailed statistical analysis of the survey results, which provide upper limits on the fractions of stars with giant planet or low mass brown dwarf companions, is presented. Assuming a planet mass distribution dn/dm {proportional_to} m{sup -1.2} and a semi-major axis distribution dn/da {proportional_to} a{sup -1}, the upper limits on the fraction of stars with at least one planet of mass 0.5-13 M{sub Jup} are 0.29 for the range 10-25 AU, 0.13 for 25-50 AU, and 0.09 for 50-250 AU, with a 95% confidence level; this result is weakly dependent on the semi-major axis distribution power-law index. Without making any assumption on the mass and semi-major axis distributions, the fraction of stars with at least one brown dwarf companion having a semi-major axis in the

  4. Measuring methyl bromide emissions from fields

    SciTech Connect

    Yates, S.R.; Gan, J.; Ernst, F.F.; Yates, M.V.

    1995-12-31

    Methyl bromide is used extensively for pest control. Recent evidence suggests that methyl bromide may react with stratospheric ozone and, due to the Clean Air Act, is scheduled for phase-out within the next 5 to 10 years. As indicated in a recent report from The National Agricultural Pesticide Impact Assessment Program, there will be substantial economic impact on the agricultural community if the use of methyl bromide is restricted. There are several areas of uncertainty concerning the agricultural use of methyl bromide. Foremost is the quantification of mass emitted to the atmosphere from agricultural fields. To address this, two field experiments were conducted to directly measure methyl bromide emissions. In the first experiment, methyl bromide was injected at approximately 25 cm depth and the soil was covered with 1 mil high-density polyethylene plastic. The second experiment was similar except that methyl bromide was injected at approximately 68 cm depth and the soil was not covered. From these experiments, the emission rate into the atmosphere and the subsurface transport of methyl bromide was determined. Both experiments include a field-scale mass balance to verify the accuracy of the flux-measurement methods as well as to check data consistency. The volatilization rate and mass lost was determined from estimates of the degradation and from several atmospheric and chamber flux methods.

  5. Experience with a new approach for instrument software at Gemini

    NASA Astrophysics Data System (ADS)

    Núñez, Arturo; Walker, Shane; Goodsell, Stephen; Dunn, Jennifer; Gillies, Kim

    2010-07-01

    Gemini Observatory is using a new approach with instrument software that takes advantage of the strengths of our instrument builders and at the same time better supports our own operational needs. A lightweight software library in conjunction with modern agile software development methodologies is being used to ameliorate the problems encountered with the development of the first and second-generation Gemini instruments. Over the last two years, Gemini and the team constructing the software for the Gemini Planet Imager (GPI) have been using an agile development process to implement the Gemini Instrument Application Interface (GIAPI) and the highlevel control software for the GPI instrument. The GPI is being tested and exercised with the GIAPI, and this has allowed us to perform early end-to-end testing of the instrument software. Early in 2009 for the first time in our development history, we were able to move instrument mechanisms with Gemini software during early instrument construction. As a result of this approach, we discovered and fixed software interface issues between Gemini and GPI. Resolving these problems at this stage is simpler and less expensive than when the full instrument is completed. GPI is currently approaching its integration and testing phase, which will occur in 2010. We expect that utilizing this new approach will yield a more robust software implementation resulting in smoother instrument integration, testing, and commissioning phases. In this paper we describe the key points of our approach and results of applying the new instrument API approach together with agile development methodologies. The paper concludes with lessons learned and suggestions for adapting agile approaches in other astronomy development projects.

  6. GEO-ENGINEERING MODELING THROUGH INTERNET INFORMATICS (GEMINI)

    SciTech Connect

    W. Lynn Watney; John H. Doveton

    2004-05-13

    GEMINI (Geo-Engineering Modeling through Internet Informatics) is a public-domain web application focused on analysis and modeling of petroleum reservoirs and plays (http://www.kgs.ukans.edu/Gemini/index.html). GEMINI creates a virtual project by ''on-the-fly'' assembly and analysis of on-line data either from the Kansas Geological Survey or uploaded from the user. GEMINI's suite of geological and engineering web applications for reservoir analysis include: (1) petrofacies-based core and log modeling using an interactive relational rock catalog and log analysis modules; (2) a well profile module; (3) interactive cross sections to display ''marked'' wireline logs; (4) deterministic gridding and mapping of petrophysical data; (5) calculation and mapping of layer volumetrics; (6) material balance calculations; (7) PVT calculator; (8) DST analyst, (9) automated hydrocarbon association navigator (KHAN) for database mining, and (10) tutorial and help functions. The Kansas Hydrocarbon Association Navigator (KHAN) utilizes petrophysical databases to estimate hydrocarbon pay or other constituent at a play- or field-scale. Databases analyzed and displayed include digital logs, core analysis and photos, DST, and production data. GEMINI accommodates distant collaborations using secure password protection and authorized access. Assembled data, analyses, charts, and maps can readily be moved to other applications. GEMINI's target audience includes small independents and consultants seeking to find, quantitatively characterize, and develop subtle and bypassed pays by leveraging the growing base of digital data resources. Participating companies involved in the testing and evaluation of GEMINI included Anadarko, BP, Conoco-Phillips, Lario, Mull, Murfin, and Pioneer Resources.

  7. Gemini-IFU spectroscopy of HH 111

    SciTech Connect

    Cerqueira, A. H.; Vasconcelos, M. J.; Feitosa, J.; Plana, H.; Raga, A. C.

    2015-03-01

    We present new optical observations of the Herbig–Haro (HH) 111 jet using the Gemini Multi Object Spectrograph in its Integral Field Unit mode. Eight fields of 5{sup ′′}×3.{sup ′′}5 have been positioned along and across the HH 111 jet, covering the spatial region from knot E to L in HH 111 (namely, knots E, F, G, H, J, K, and L). We present images and velocity channel maps for the [O i] 6300+6360, Hα, [N ii] 6548+6583, and [S ii] 6716+6730 lines, as well as for the [S ii] 6716/6730 line ratio. We find that the HH 111 jet has an inner region with lower excitation and higher radial velocity, surrounded by a broader region of higher excitation and lower radial velocity. Also, we find higher electron densities at lower radial velocities. These results imply that the HH 111 jet has a fast, axial region with lower velocity shocks surrounded by a lower velocity sheath with higher velocity shocks.

  8. Gemini planet imager observational calibrations VII: on-sky polarimetric performance of the Gemini planet imager

    NASA Astrophysics Data System (ADS)

    Wiktorowicz, Sloane J.; Millar-Blanchaer, Max; Perrin, Marshall D.; Graham, James R.; Fitzgerald, Michael P.; Maire, Jérôme; Ingraham, Patrick; Savransky, Dmitry; Macintosh, Bruce A.; Thomas, Sandrine J.; Chilcote, Jeffrey K.; Draper, Zachary H.; Song, Inseok; Cardwell, Andrew; Goodsell, Stephen J.; Hartung, Markus; Hibon, Pascale; Rantakyrö, Fredrik; Sadakuni, Naru

    2014-07-01

    We present on-sky polarimetric observations with the Gemini Planet Imager (GPI) obtained at straight Cassegrain focus on the Gemini South 8-m telescope. Observations of polarimetric calibrator stars, ranging from nearly un- polarized to strongly polarized, enable determination of the combined telescope and instrumental polarization. We find the conversion of Stokes I to linear and circular instrumental polarization in the instrument frame to be I --> (QIP, UIP, PIP, VIP) = (-0.037 +/- 0.010%, +0.4338 +/- 0.0075%, 0.4354 +/- 0.0075%, -6.64 +/- 0.56%). Such precise measurement of instrumental polarization enables ~0.1% absolute accuracy in measurements of linear polarization, which together with GPI's high contrast will allow GPI to explore scattered light from circumstellar disk in unprecedented detail, conduct observations of a range of other astronomical bodies, and potentially even study polarized thermal emission from young exoplanets. Observations of unpolarized standard stars also let us quantify how well GPI's differential polarimetry mode can suppress the stellar PSF halo. We show that GPI polarimetry achieves cancellation of unpolarized starlight by factors of 100-200, reaching the photon noise limit for sensitivity to circumstellar scattered light for all but the smallest separations at which the calibration for instrumental polarization currently sets the limit.

  9. Large-scale, low-cost synthesis of monodispersed gold nanorods using a gemini surfactant

    NASA Astrophysics Data System (ADS)

    Xu, Yong; Zhao, Yang; Chen, Lei; Wang, Xuchun; Sun, Jianxia; Wu, Haihua; Bao, Feng; Fan, Jian; Zhang, Qiao

    2015-04-01

    In this work, we demonstrate that monodispersed gold nanorods (AuNRs) can be obtained in a large-scale and cost-effective way. By using an industrial grade gemini surfactant (P16-8-16), the cost of the synthesis of high-quality AuNRs can be significantly reduced by 90%. The synthesis can be scaled up to over 4 L. The aspect ratio of AuNRs can be well tuned from ~2.4 to ~6.3, resulting in a wide tunability of the SPR properties. Systematic studies reveal that P16-8-16 could have a dual function: it can not only act as a capping ligand to stabilize AuNRs but also it can pre-reduce Au3+ to Au+ by the unsaturated C&z.dbd;C bond. Furthermore, the shape of AuNRs can be tailored from straight nanorods to ``dog-bones'' by simply varying the concentration of the surfactant. A mechanistic study shows that the shape change can be attributed to the presence of excess bromide ions because of the complex effect between bromide ions and gold ions. This work will not only help to achieve the industrial production of AuNRs, but also promote research into practical applications of various nanomaterials.In this work, we demonstrate that monodispersed gold nanorods (AuNRs) can be obtained in a large-scale and cost-effective way. By using an industrial grade gemini surfactant (P16-8-16), the cost of the synthesis of high-quality AuNRs can be significantly reduced by 90%. The synthesis can be scaled up to over 4 L. The aspect ratio of AuNRs can be well tuned from ~2.4 to ~6.3, resulting in a wide tunability of the SPR properties. Systematic studies reveal that P16-8-16 could have a dual function: it can not only act as a capping ligand to stabilize AuNRs but also it can pre-reduce Au3+ to Au+ by the unsaturated C&z.dbd;C bond. Furthermore, the shape of AuNRs can be tailored from straight nanorods to ``dog-bones'' by simply varying the concentration of the surfactant. A mechanistic study shows that the shape change can be attributed to the presence of excess bromide ions because of the

  10. Gemini Planet Imager First Light and Campaign Survey

    NASA Astrophysics Data System (ADS)

    Patience, J.; Macintosh, B. A.; Graham, J. R.; Gpies Team

    2014-03-01

    Detecting, characterizing, and modeling exoplanets are among the fastestgrowing and highest-profile fields in current international astrophysics research. With direct imaging, it is possible to investigate the frequency of planetary systems with an architecture similar to that of the Solar System by detecting Jupiter-like planets in orbits comparable to the location of the giant planets in the Solar System. The detection and characterization of a new population of wide orbit exoplanets is essential to obtain a full census of planetary systems and to provide crucial tests of planet formation and evolution theories. Directly imaged planets also present important systems for which the atmospheric properties can be characterized. Achieving this potential is the fundamental goal of the Gemini Planet Imager (GPI). GPI, a facility instrument for the Gemini South Observatory, will be the most sensitive planet imager ever constructed, an order of magnitude more powerful than current facilities and capable of discovering young (<1 GYr) planets from 5-100 AU. The Gemini Observatory has allocated our team 890 hours of telescope time to carry out the Gemini Planet Imager Exoplanet Survey (GPIES) - the largest single allocation in the history of Gemini. The GPIES survey is designed to observe ~600 young, nearby stars, at high sensitivity, optimized to provide detection and basic characterization of 20-50 1-10 MJ planets.

  11. Gemini, a Bifunctional Enzymatic and Fluorescent Reporter of Gene Expression

    PubMed Central

    Endy, Drew

    2009-01-01

    Background The development of collections of quantitatively characterized standard biological parts should facilitate the engineering of increasingly complex and novel biological systems. The existing enzymatic and fluorescent reporters that are used to characterize biological part functions exhibit strengths and limitations. Combining both enzymatic and fluorescence activities within a single reporter protein would provide a useful tool for biological part characterization. Methodology/Principal Findings Here, we describe the construction and quantitative characterization of Gemini, a fusion between the β-galactosidase (β-gal) α-fragment and the N-terminus of full-length green fluorescent protein (GFP). We show that Gemini exhibits functional β-gal activity, which we assay with plates and fluorometry, and functional GFP activity, which we assay with fluorometry and microscopy. We show that the protein fusion increases the sensitivity of β-gal activity and decreases the sensitivity of GFP. Conclusions/Significance Gemini is therefore a bifunctional reporter with a wider dynamic range than the β-gal α-fragment or GFP alone. Gemini enables the characterization of gene expression, screening assays via enzymatic activity, and quantitative single-cell microscopy or FACS via fluorescence activity. The analytical flexibility afforded by Gemini will likely increase the efficiency of research, particularly for screening and characterization of libraries of standard biological parts. PMID:19888458

  12. Sky Background Variability Measured on Maunakea at Gemini North Observatory

    NASA Astrophysics Data System (ADS)

    Smith, Adam B.; Roth, Katherine; Stephens, Andrew W.

    2016-01-01

    Gemini North has recently implemented a Quality Assessment Pipeline (QAP) that automatically reduces images in realtime to determine sky condition quantities, including background sky brightness from the optical to near-infrared. Processing archived images through the QAP and mining the results allows us to look for trends and systematic issues with the instruments and optics during the first decade of Gemini.Here we present the results of using the QAP calculated values to quantify how airglow affects the background sky brightness of images taken with Gemini's imaging instruments, GMOS and NIRI, as well as searching for other factors that may cause changes in the sky brightness. By investigating the dependence of measured sky brightness as a function of a variety of variables, including time after twilight, airmass, season, distance from the moon, air temperature, etc., we quantify the effect of sky brightness and its impact on the sensitivity of Gemini optical and near-infrared imaging data. These measurements will be used to determine new sky background relationships for Maunakea, and to improve the Gemini Integration Time Calculators (ITCs).

  13. Close-up view of Gemini 9 spacecraft taken during EVA

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Astronaut Eugene A. Cernan took this close-up view of the Gemini 9 spacecraft during his extravehicular activity on the Gemini 9 mission. Taken during the 32nd revolution of the 72 hr. 21 min. space flight.

  14. Astronaut Virgil Grissom shown through window of open hatch on Gemini craft

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Astronaut Virgil I. Grissom, the command pilot of the Gemini-Titan 3 three orbit mission, is shown through the window of the open hatch on Gemini spacecraft in the white room on the mornining of the launch.

  15. Interactions of cationic trimeric, gemini and monomeric surfactants with trianionic curcumin in aqueous solution.

    PubMed

    Wang, Meina; Wu, Chunxian; Tang, Yongqiang; Fan, Yaxun; Han, Yuchun; Wang, Yilin

    2014-05-21

    Interactions of trianionic curcumin (Cur(3-)) with a series of cationic surfactants, monomeric surfactant dodecyl trimethylammonium bromide (DTAB), dimeric surfactant hexamethylene-1,6-bis(dodecyldimethylammonium bromide) (12-6-12) and trimeric surfactant tri(dodecyldimethylammonioacetoxy)diethyltriamine trichloride (DTAD), have been investigated in aqueous solution of pH 13.0. Surface tension and spectral measurements indicate that the cationic surfactants display a similar surfactant concentration dependent interaction process with Cur(3-), involving three interaction stages. At first the three cationic surfactants electrostatically bind on Cur(3-) to form the surfactant-Cur(3-) complex. Then the bound and unbound cationic surfactants with Cur(3-) aggregate into surfactant-Cur(3-) mixed micelles through hydrophobic interactions above the critical micelle concentration of the surfactants (CMCC) in the presence of Cur(3-). Finally excess unbound surfactants self-assemble into micelles like those without Cur(3-). For all the three surfactants, the addition of Cur(3-) only decreases the critical micelle concentration of 12-6-12 but does not affect the critical micelle concentration of DTAB and DTAD. As the oligomeric degree of surfactants increases, the intermolecular interaction of the cationic surfactants with Cur(3-) increases and the surfactant amount needed for Cur(3-) encapsulation decreases. Compared with 12-6-12, either the weaker interaction of DTAB with Cur(3-) or stronger interaction of DTAD with Cur(3-) limits the stability or solubility of Cur(3-) in surfactant micelles. Therefore, gemini surfactant 12-6-12 is the best choice to effectively suppress Cur(3-) degradation at very low concentrations. Isothermal titration microcalorimetry, surface tension and (1)H NMR results reveal that 12-6-12 and Cur(3-) form a (12-6-12)2-Cur(3-) complex and start to form micelles at extremely decreased concentrations, where either 12-6-12 or Cur(3-) works as a bridge

  16. How the Type of Cosurfactant Impacts Strongly on the Size and Interfacial Composition in Gemini 12-2-12 RMs Explored by DLS, SLS, and FTIR Techniques.

    PubMed

    Cuenca, Victor E; Falcone, R Darío; Silber, Juana J; Correa, N Mariano

    2016-01-28

    The limited amount of information about reverse micelles (RMs) made with gemini surfactants, the effect of the n-alcohols in their interface, and the water-entrapped structure in the polar core motivated us to perform this work. Thus, in the present contribution, we use dynamic light scattering (DLS), static light scattering (SLS), and FT-IR techniques to obtain information on RMs structure created, with the gemini dimethylene-1,2-bis(dodecyldimethylammonium) bromide (G12-2-12) surfactant and compare the results with its monomer: dodecyltrimethylammonium bromide (DTAB). In this way, the size of the aggregates formed in different nonpolar organic solvents, the effect of the chain length of n-alcohols used as cosurfactants, and the water-entrapped structure were explored. The data show that the structure of the cosurfactant needed to stabilize the RMs plays a fundamental role, affecting the size and behavior of the aggregates. In contrast to what happens with the RMs formed with the monomer DTAB, water entrapped inside G12-2-12 RMs displays different interaction with the interface depending on the hydrocarbon chain length of the n-alcohol used as cosurfactant. Thus, n-pentanol and n-octanol molecules are located in different regions in the RMs interfaces formed with the gemini surfactant. n-Octanol locates at the RMs interface among the surfactant hydrocarbon tails increasing the water-surfactant polar headgroup interaction. On the other hand, n-pentanol locates at the RMs interface near the polar core, limiting the interaction of water with the micellar inner interface and favoring the water-water interaction in the polar core.

  17. Potassium bromide method of infrared sampling

    USGS Publications Warehouse

    Milkey, R.G.

    1958-01-01

    In the preparation of potassium bromide pressed windows for use in the infrared analysis of solids, severe grinding of the potassium bromide powder may produce strong absorption bands that could interfere seriously with the spectra of the sample. These absorption bands appear to be due to some crystal alteration of the potassium bromide as a result of the grinding process. They were less apt to occur when the coarser powder, which had received a relatively gentle grinding, was used. Window blanks prepared from the coarser powders showed smaller adsorbed water peaks and generally higher over-all transmittance readings than windows pressed from the very fine powders.

  18. The system support associate model at Gemini Observatory

    NASA Astrophysics Data System (ADS)

    Hainaut, Marie-Claire; Coulson, Dolores

    2008-07-01

    At Gemini Observatory, the traditional employment position of telescope operator has been discarded in favor of a more diverse and flexible position known as System Support Associate (SSA). From the very beginning, the operational model of Gemini was designed to involve SSAs in observatory projects well beyond the strict operation of the telescope systems. We describe the motivation behind the original model, how it was eventually implemented and how it has evolved. We describe how the schedule allows SSAs to assume different roles within Gemini and how flexible time allows them to participate to a wide range of projects, increasing their motivation, deepening their knowledge and strengthening communication between groups, as well as allowing management to allocate resources to projects that would otherwise lack manpower. We give examples of such projects and comment on the difficulties inherent in the model.

  19. Thermal emissivity analysis of a GEMINI 8-meter telescopes design

    NASA Technical Reports Server (NTRS)

    St. Clair Dinger, Ann

    1993-01-01

    The GEMINI 8-meter Telescopes Project is designing twin 8-meter telescopes to be located in Hawaii and Chile. The GEMINI telescopes will have interchangeable secondary mirrors for use in the visible and IR. The APART/PADE program is being used to evaluate the effective IR emissivity of the IR configuration plus enclosure as a function of mirror contamination at three IR wavelengths. The goal is to design a telescope whose effective IR emissivity is no more than 2 percent when the mirrors are clean.

  20. Gemini 4 astronauts relax aboard Navy helicopter after recovery

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Gemini 4 astronauts, James A. McDivitt (right), command pilot, and Edward H. White II, (left), pilot, relax aboard a U.S. Navy helicopter on their way to the aircraft carrier U.S.S. Wasp after recovery from the Gemini 4 spacecraft. They had been picked up out of the Atlantic Ocean following a successful splashdown (33532); White (left) and McDivitt listen to the voice of President Lyndon B. Johnson as he congratulated them by telephone on the successful mission. They are shown aboard the carrier U.S.S. Wasp just after their recovery (33533).

  1. The Gemini Planet Imager: From Science to Design to Construction

    SciTech Connect

    Macintosh, B; Graham, J R; Palmer, D; Doyon, R; Dunn, J; Gavel, D; Larkin, J; Oppenheimer, B; Saddlemyer, L; Sivaramakrishnan, A; Wallace, J K; Bauman, B; Erickson, D; Marois, C; Poyneer, L; Soummer, R

    2008-07-01

    The Gemini Planet Imager (GPI) is a facility instrument under construction for the 8-m Gemini South telescope. It combines a 1500 subaperture AO system using a MEMS deformable mirror, an apodized-pupil Lyot coronagraph, a high-accuracy IR interferometer calibration system, and a near-infrared integral field spectrograph to allow detection and characterization of self-luminous extrasolar planets at planet/star contrast ratios of 10{sup -7}. I will discuss the evolution from science requirements through modeling to the final detailed design, provide an overview of the subsystems and show models of the instrument's predicted performance.

  2. Performance of the Gemini Planet Imager's adaptive optics system.

    PubMed

    Poyneer, Lisa A; Palmer, David W; Macintosh, Bruce; Savransky, Dmitry; Sadakuni, Naru; Thomas, Sandrine; Véran, Jean-Pierre; Follette, Katherine B; Greenbaum, Alexandra Z; Ammons, S Mark; Bailey, Vanessa P; Bauman, Brian; Cardwell, Andrew; Dillon, Daren; Gavel, Donald; Hartung, Markus; Hibon, Pascale; Perrin, Marshall D; Rantakyrö, Fredrik T; Sivaramakrishnan, Anand; Wang, Jason J

    2016-01-10

    The Gemini Planet Imager's adaptive optics (AO) subsystem was designed specifically to facilitate high-contrast imaging. A definitive description of the system's algorithms and technologies as built is given. 564 AO telemetry measurements from the Gemini Planet Imager Exoplanet Survey campaign are analyzed. The modal gain optimizer tracks changes in atmospheric conditions. Science observations show that image quality can be improved with the use of both the spatially filtered wavefront sensor and linear-quadratic-Gaussian control of vibration. The error budget indicates that for all targets and atmospheric conditions AO bandwidth error is the largest term.

  3. Distributed user support and the Gemini Observatory help desk

    NASA Astrophysics Data System (ADS)

    Chan, Simon; Puxley, Phil J.

    2000-07-01

    The Gemini Observatory HelpDesk was activated early in 2000 to aid in the rapid and accurate resolution of queries concerning the Gemini telescopes and their capabilities. This system co- ordinates user support amongst staff within the Observatory and at National Offices in each partner country. The HelpDesk is based on a commercial product from Remedy Corporation that logs, tracks, forwards and escalates queries and self- generates a knowledgebase of previously asked questions. Timestamping of these events in the life cycle of a request and analysis of associated information provides valuable feedback on the static web content and performance of user support.

  4. Emission of methyl bromide from biomass burning

    SciTech Connect

    Manoe, S.; Andreae, M.O. )

    1994-03-04

    Bromine is, per atom, far more efficient than chlorine in destroying stratospheric ozone, and methyl bromide is the single largest source of stratospheric bromine. The two main previously known sources of this compound are emissions from the ocean and from the compound's use as an agricultural pesticide. Laboratory biomass combustion experiments showed that methyl bromide was emitted in the smoke from various fuels tested. Methyl bromide was also found in smoke plumes from wildfires in savannas, chaparral, and boreal forest. Global emissions of methyl bromide from biomass burning are estimated to be in the range of 10 to 50 gigagrams per year, which is comparable to the amount produced by ocean emission and pesticide use and represents a major contribution ([approximately]30 percent) to the stratospheric bromine budget.

  5. Investigation of drug interactions with pinaverium bromide.

    PubMed

    Devred, C; Godeau, P; Guerot, C; Librez, P; Mougeot, G; Orsetti, A; Segrestaa, J M

    1986-01-01

    A series of studies was carried out at 6 centres to investigate possible drug interaction between the spasmolytic, pinaverium bromide, and cardiac glycosides, anticoagulants and hypoglycaemic agents given to patients as part of the long-term treatment of their condition. The results of clinical and laboratory investigations did not show any evidence of pinaverium bromide interfering with the action or activity of any of the drugs studied. PMID:3084176

  6. GEMINI-GMOS spectroscopy in the Antlia cluster

    NASA Astrophysics Data System (ADS)

    Faifer, F.; Smith Castelli, A. V.; Bassino, L. P.; Richtler, T.; Cellone, S. A.

    : We present preliminary results of a spectroscopic study performed in the Antlia cluster through GEMINI-GMOS data. They are related with new radial velocities that allow us to confirm the cluster membership of several new faint galaxies, as well as to identify very interesting background objects.

  7. Gemini 12 crew arrives aboard U.S.S. Wasp

    NASA Technical Reports Server (NTRS)

    1966-01-01

    A happy Gemini 12 prime crew arrives aboard the aircraft carrier, U.S.S. Wasp. Astronauts James A. Lovell Jr. (left), command pilot, and Edwin E. Aldrin Jr., pilot, had just been picked up from the splashdown area by helicopter.

  8. Designing Scalable PGAS Communication Subsystems on Cray Gemini Interconnect

    SciTech Connect

    Vishnu, Abhinav; Daily, Jeffrey A.; Palmer, Bruce J.

    2012-12-26

    The Cray Gemini Interconnect has been recently introduced as a next generation network architecture for building multi-petaflop supercomputers. Cray XE6 systems including LANL Cielo, NERSC Hopper, ORNL Titan and proposed NCSA BlueWaters leverage the Gemini Interconnect as their primary Interconnection network. At the same time, programming models such as the Message Passing Interface (MPI) and Partitioned Global Address Space (PGAS) models such as Unified Parallel C (UPC) and Co-Array Fortran (CAF) have become available on these systems. Global Arrays is a popular PGAS model used in a variety of application domains including hydrodynamics, chemistry and visualization. Global Arrays uses Aggregate Re- mote Memory Copy Interface (ARMCI) as the communication runtime system for Remote Memory Access communication. This paper presents a design, implementation and performance evaluation of scalable and high performance communication subsystems on Cray Gemini Interconnect using ARMCI. The design space is explored and time-space complexities of commu- nication protocols for one-sided communication primitives such as contiguous and uniformly non-contiguous datatypes, atomic memory operations (AMOs) and memory synchronization is presented. An implementation of the proposed design (referred as ARMCI-Gemini) demonstrates the efficacy on communication primitives, application kernels such as LU decomposition and full applications such as Smooth Particle Hydrodynamics (SPH) application.

  9. Gemini photographs of the world: A complete index

    NASA Technical Reports Server (NTRS)

    Giddings, L. E.

    1977-01-01

    The most authoritative catalogs of photographs of all Gemini missions are assembled. Included for all photographs are JSC (Johnson Space Center) identification number, percent cloud cover, geographical area in sight, and miscellaneous information. In addition, details are given on cameras, filters, films, and other technical details.

  10. Gemini high-resolution optical spectrograph conceptual design

    NASA Astrophysics Data System (ADS)

    Szeto, Kei; McConnachie, Alan; Anthony, André; Bohlender, David; Crampton, David; Desaulniers, Pierre; Dunn, Jennifer; Hardy, Tim; Hill, Alexis; Monin, Dmitry; Pazder, John; Schwab, Christian; Spano, Paola; Starkenburg, Else; Thibault, Simon; Walker, Gordon; Venn, Kim; Zhang, Hu

    2012-09-01

    A multiplexed moderate resolution (R = 34,000) and a single object high resolution (R = 90,000) spectroscopic facility for the entire 340 - 950nm wavelength region has been designed for Gemini. The result is a high throughput, versatile instrument that will enable precision spectroscopy for decades to come. The extended wavelength coverage for these relatively high spectral resolutions is achieved by use of an Echelle grating with VPH cross-dispersers and for the R = 90,000 mode utilization of an image slicer. The design incorporates a fast, efficient, reliable system for acquiring targets over the7 arcmin field of Gemini. This paper outlines the science case development and requirements flow-down process that leads to the configuration of the HIA instrument and describes the overall GHOS conceptual design. In addition, this paper discusses design trades examined during the conceptual design study instrument group of the Herzberg Institute of Astrophysics has been commissioned by the Gemini Observatory as one of the three competing organizations to conduct a conceptual design study for a new Gemini High-Resolution Optical Spectrograph (GHOS). This paper outlines the science case development and requirements flow-down process that leads to the configuration of the HIA instrument and describes the overall GHOS conceptual design. In addition, this paper discusses design trades examined during the conceptual design study.

  11. Classification of 3 DES supernovae by Gemini-North

    NASA Astrophysics Data System (ADS)

    Pan, Y.-C.; Foley, R. J.; Maartens, R.; Gupta, R.; Kovacs, E.; Kuhlmann, S.; Spinka, H.; Ahn, E.; Finley, D. A.; Frieman, J.; Marriner, J.; Wester, W.; Aldering, G.; Kim, A. G.; Thomas, R. C.; Barbary, K.; Bloom, J. S.; Goldstein, D.; Nugent, P.; Perlmutter, S.; Casas, R.; Castander, F. J.; Desai, S.; Paech, K.; Smith, R. C.; Schubnell, M.; Kessler, R.; Lasker, J.; Scolnic, D.; Brout, D. J.; Gladney, L.; Sako, M.; Wolf, R. C.; Brown, P. J.; Krisciunas, K.; Suntzeff, N.; Nichol, R.; Papadopoulos, A.; Childress, M.; D'Andrea, C.; Smith, M.; Sullivan, M.

    2015-11-01

    We report optical spectroscopy of 3 supernovae discovered by the Dark Energy Survey. The spectra (380-820nm) were obtained using GMOS on Gemini-North. Object classification was performed using SNID (Blondin & Tonry, 2007, ApJ, 666, 1024) and superfit (Howell et al, 2005, ApJ, 634, 119), the details of which are reported in the table below.

  12. Gemini Multi-Object Spectrograph Upgrades: Hamamatsu CCDs and AO

    NASA Astrophysics Data System (ADS)

    Roth, Katherine; Gimeno, G.; Murowinski, R.; Kleinman, S.; Trujillo, C. A.; Lai, O.

    2014-01-01

    The Gemini Multi-Object Spectrographs (GMOS) at both Gemini North and South have provided crucial access to longslit, MOS and IFU moderate resolution optical spectroscopy for the Gemini international partnership for over a decade. The interim installment of e2v deep depletion CCDs at GMOS-N in November 2011, providing enhanced red sensitivity, was the first major upgrade for either GMOS since the implementation of the Nod&Shuffle mode in 2002. We present plans to replace the original EEV detectors in GMOS-S with new Hamamatsu CCDs, extending wavelength coverage out beyond 1.03 microns. GMOS-N upgrade to Hamamatsu CCDs will follow the successful deployment on GMOS-S. With the extension of GMOS sensitivity further to long wavelengths it becomes even more attractive to extend the number of observing modes to include adaptive optics imaging and spectroscopy. As has already been demonstrated with GEMS/GMOS-S imaging, adaptive optics in the 0.8-1 micron wavelength regime on Gemini can effectively transform IQ70 conditions to IQ20 and more than double the spatial resolution over the natural seeing. We present plans to move forward with plans to enable GMOS + adaptive optics as a regular user mode at both sites.

  13. Gemini 8 prime and backup crews during press conference

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Gemini 8 prime and backup crews during press conference. Left to right are Astronauts David R. Scott, prime crew pilot; Neil A. Armstrong, prime crew command pilot; Charles Conrad Jr., backup crew command pilot; and Richard F. Gordon Jr., backup crew pilot.

  14. Gemini Series Experiment Data Reduction and Storage Techniques

    SciTech Connect

    R. A. Berglin

    2011-11-01

    The presentation covers data formats expected from Gemini experiments; data quick look vs. in-depth analysis; iPDV object-oriented data storage; iPDV's traceability of analysis results; optimizing object memory usage in iPDV; and long-term archival of data objects by iPDV.

  15. Astrometric Calibration of the Gemini NICI Planet-Finding Campaign

    NASA Astrophysics Data System (ADS)

    Hayward, Thomas L.; Biller, Beth A.; Liu, Michael C.; Nielsen, Eric L.; Wahhaj, Zahed; Chun, Mark; Ftaclas, Christ; Hartung, Markus; Toomey, Douglas W.

    2014-12-01

    We describe the astrometric calibration of the Gemini NICI Planet-Finding Campaign. The Campaign requires a relative astrometric accuracy of ≈20 mas across multiyear timescales in order to distinguish true companions from background stars by verifying common proper motion and parallax with their parent stars. The calibration consists of a correction for instrumental optical image distortion, plus on-sky imaging of astrometric fields to determine the pixel scale and image orientation. We achieve an accuracy of lsim7 mas between the center and edge of the 18'' NICI field, meeting the 20 mas requirement. Most of the Campaign data in the Gemini Science Archive are accurate to this level but we identify a number of anomalies and present methods to correct the errors. Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc. under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência, Tecnologia e Inovação (Brazil), and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina).

  16. Novel fluorinated gemini surfactants with γ-butyrolactone segments.

    PubMed

    Kawase, Tokuzo; Okada, Kazuyuki; Oida, Tatsuo

    2015-01-01

    In this work, novel γ-butyrolactone-type monomeric and dimeric (gemini) surfactants with a semifluoroalkyl group [Rf- (CH2)3-; Rf = C4F9, C6F13, C8F17] as the hydrophobic group were successfully synthesized. Dimethyl malonate was dimerized or connected using Br(CH2)sBr (s = 0, 1, 2, 3) to give tetraesters, and they were bis-allylated. Radical addition of fluoroalkyl using Rf-I and an initiator, i.e., 2,2'-azobisisobutyronitrile for C4F9 or di-t-butyl peroxide for C6F13 and C8F17, was perform at high temperature, with prolonged heating, to obtain bis(semifluoroalkyl)-dilactone diesters. These dilactone diesters were hydrolyzed using KOH/EtOH followed by decarboxylation in AcOH to afford γ-butyrolactonetype gemini surfactants. Common 1 + 1 semifluoroalkyl lactone surfactants were synthesized using the same method. Their surfactant properties [critical micelle concentration (CMC), γCMC, pC20, ΓCMC, and AG] were investigated by measuring the surface tension of the γ-hydroxybutyrate form prepared in aqueous tetrabutylammonium hydroxide solution. As expected, the CMC values of the gemini surfactants were more than one order of magnitude smaller than those of the corresponding 1 + 1 surfactants. Other properties also showed the excellent ability of the gemini structure to reduce the surface tension. These surfactants were easily and quantitatively recovered by acidification. The monomeric surfactant was recovered in the γ-hydroxybutyric acid form, and the gemini surfactant as a mixture of γ-butyrolactone and γ-hydroxybutyric acid forms.

  17. Gemini Planet Imager: Preliminary Design Report

    SciTech Connect

    Macintosh, B

    2007-05-10

    For the first time in history, direct and indirect detection techniques have enabled the exploration of the environments of nearby stars on scales comparable to the size of our solar system. Precision Doppler measurements have led to the discovery of the first extrasolar planets, while high-contrast imaging has revealed new classes of objects including dusty circumstellar debris disks and brown dwarfs. The ability to recover spectrophotometry for a handful of transiting exoplanets through secondary-eclipse measurements has allowed us to begin to study exoplanets as individual entities rather than points on a mass/semi-major-axis diagram and led to new models of planetary atmospheres and interiors, even though such measurements are only available at low SNR and for a handful of planets that are automatically those most modified by their parent star. These discoveries have galvanized public interest in science and technology and have led to profound new insights into the formation and evolution of planetary systems, and they have set the stage for the next steps--direct detection and characterization of extrasolar Jovian planets with instruments such as the Gemini Planet Imager (GPI). As discussed in Volume 1, the ability to directly detect Jovian planets opens up new regions of extrasolar planet phase space that in turn will inform our understanding of the processes through which these systems form, while near-IR spectra will advance our understanding of planetary physics. Studies of circumstellar debris disks using GPI's polarimetric mode will trace the presence of otherwise-invisible low-mass planets and measure the build-up and destruction of planetesimals. To accomplish the science mission of GPI will require a dedicated instrument capable of achieving contrast of 10{sup -7} or more. This is vastly better than that delivered by existing astronomical AO systems. Currently achievable contrast, about 10{sup -5} at separations of 1 arc second or larger, is

  18. Mutagenic effects of lead (II) bromide.

    PubMed

    Maslat, A O; Haas, H J

    1989-12-01

    The mutagenicity of lead (II) bromide (a combustion product of the gasoline additives lead (IV) tetraethyl and 1,2-dibromoethane) was investigated using various strains of bacteria. Taking prodigiosin (the red pigment) production as a marker, lead (II) bromide was found to be mutagenic in S. marcescens, leading to the appearance of white mutant colonies that are unable to produce such a pigment. This compound was also found to be mutagenic in E. coli KMBL1851, resulting in the appearance of rifampicin-resistant mutants in addition to Met+ and His+ revertants. Some of the S. marcescens mutants were found to be reversible, able to resynthesize prodigiosin. Differences in the sensitivity to antibiotics as well as in the biochemical properties were detected between the mutants and their corresponding wild types. Lead (II) bromide gave positive results in the Ames test performed with strain TA 1535.

  19. Neutron reflectometry of quaternary gemini surfactants as a function of alkyl chain length: anomalies arising from ion association and premicellar aggregation.

    PubMed

    Li, Pei Xun; Dong, Chu Chuan; Thomas, Robert K; Penfold, J; Wang, Yilin

    2011-03-15

    We have measured the structure and properties of a series of dicationic quaternary ammonium compounds α,ω-bis(N-alkyl dimethyl ammonium)hexane halides (Cn-C6-Cn) for values of the alkyl chain length n of 8, 9, 10, 11, 12, and 16, and a series of α,ω-bis(N-alkyl dimethyl ammonium)diethylether halides (Cn-C2OC2-Cn) for values of n of 8, 12, and 16, as well as C8-C12-C8 and C12-C10-C12 at the air/water interface. Although the critical micelle concentration (CMC) in the two series decreases in the normal way, that is, logarithmically, with increasing chain length, the limiting surface tension at the CMC and the limiting area per molecule both increase with chain length, in the opposite direction from comparable single chain surfactants. The structures of the surface layers, which were determined by neutron reflectometry, indicate that the anomalous behavior of the surface tension and area are probably caused by poor packing of the gemini side chains between adjacent molecules. Comparison of the directly determined surface coverage using neutron reflectometry and the apparent coverage determined by application of the Gibbs equation to surface tension data gives an experimental measurement of the prefactor in the Gibbs equation, which should be 3 for these geminis. It was found to vary from about 3 for the two C16 geminis down to about 1.5 for the two C8 geminis. We have devised a simple quantitative model that explains this variation and earlier observations that the Gibbs prefactor for C12-Cn-C12 (n varying from 3 to 12) is around 2. The model is consistent with the conductivity, NMR, and fluorescence measurements of other authors. This model shows that both dimerization and ion association are required to explain the surface tension behavior of cationic gemini bromide surfactants and that, in many cases, the prefactor itself varies with concentration.

  20. Effects of pinaverium bromide on Oddi's sphincter.

    PubMed

    DiSomma, C; Reboa, G; Patrone, M G; Mortola, G P; Sala, G; Ciampini, M

    1986-01-01

    Twelve to 15 days after cholecystectomy, endocholedochal pressure was measured in ten patients before and one hour after oral administration of 15 mg of pinaverium bromide (six patients) or placebo. The mean endocholedochal pressure was 7.1 +/- 0.25 mmHg before and 3.1 +/- 0.2 mmHg after pinaverium (P less than 0.01), and 7.0 +/- 0.2 and 6.8 +/- 1.2 mmHg in the placebo-treated patients. The results suggest that pinaverium bromide has a specific effect on the common bile duct and probably on Oddi's sphincter. PMID:3815457

  1. [The clinical pharmacological profile of pinaverium bromide].

    PubMed

    Guslandi, M

    1994-04-01

    Pinaverium bromide is a locally acting spasmolytic agent of the digestive tract. Its mechanism of action relies upon inhibition of calcium ion entrance into smooth muscle cells (calcium-antagonist effect). In humans pinaverium facilitates gastric emptying and decreases intestinal transit time in patients with constipation. Pinaverium is very effective in improving symptoms of irritable bowel syndrome (abdominal pain, gas, diarrhea or constipation). In this respect the drug proved to be significantly superior to placebo, at least as effective as trimebutine and on the whole more active than otilonium and prifinium bromide, being always extremely well tolerated. PMID:8028745

  2. Integration and test of the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Thomas, Sandrine J.; Poyneer, Lisa; De Rosa, Rob; Macintosh, Bruce; Dillon, Daren; Wallace, James K.; Palmer, David; Gavel, Donald; Bauman, Brian; Saddlemyer, Leslie; Goodsell, Stephen

    2011-10-01

    Exoplanet imaging is driving a race to higher contrast imaging, both from earth and from space. Next-generation instruments such as the Gemini Planet Imager (GPI) and SPHERE are designed to achieve contrast ratios of 10-6 - 10-7 this requires very good wavefront correction and coronagraphic control of diffraction. GPI is a facility instrument, now in integration and test, with first light on the 8-m Gemini South telescope expected by the middle of 2012. It combines a 1700 subaperture AO system using a MEMS deformable mirror, an apodized-pupil Lyot coronagraph, a high-accuracy IR interferometric wavefront calibration system, and a nearinfrared integral field spectrograph to allow detection and characterization of self-luminous extrasolar planets at planet/star contrast ratios of 10-7. In this paper we will discuss the status of the integration and test now taking place at the University of Santa Cruz California.

  3. Kinetics of aqueous lubrication in the hydrophilic hydrogel Gemini interface.

    PubMed

    Dunn, Alison C; Pitenis, Angela A; Urueña, Juan M; Schulze, Kyle D; Angelini, Thomas E; Sawyer, W Gregory

    2015-12-01

    The exquisite sliding interfaces in the human body share the common feature of hydrated dilute polymer mesh networks. These networks, especially when they constitute a sliding interface such as the pre-corneal tear film on the ocular interface, are described by the molecular weight of the polymer chains and a characteristic size of a minimum structural unit, the mesh size, ξ. In a Gemini interface where hydrophilic hydrogels are slid against each other, the aqueous lubrication behavior has been shown to be a function of sliding velocity, introducing a sliding timescale competing against the time scales of polymer fluctuation and relaxation at the surface. In this work, we examine two recent studies and postulate that when the Gemini interface slips faster than the single-chain relaxation time, chains must relax, suppressing the amplitude of the polymer chain thermal fluctuations.

  4. Kinetics of aqueous lubrication in the hydrophilic hydrogel Gemini interface.

    PubMed

    Dunn, Alison C; Pitenis, Angela A; Urueña, Juan M; Schulze, Kyle D; Angelini, Thomas E; Sawyer, W Gregory

    2015-12-01

    The exquisite sliding interfaces in the human body share the common feature of hydrated dilute polymer mesh networks. These networks, especially when they constitute a sliding interface such as the pre-corneal tear film on the ocular interface, are described by the molecular weight of the polymer chains and a characteristic size of a minimum structural unit, the mesh size, ξ. In a Gemini interface where hydrophilic hydrogels are slid against each other, the aqueous lubrication behavior has been shown to be a function of sliding velocity, introducing a sliding timescale competing against the time scales of polymer fluctuation and relaxation at the surface. In this work, we examine two recent studies and postulate that when the Gemini interface slips faster than the single-chain relaxation time, chains must relax, suppressing the amplitude of the polymer chain thermal fluctuations. PMID:26614802

  5. Gemini Observatory Takes its Local Communities on an Expanding Journey

    NASA Astrophysics Data System (ADS)

    Harvey, Janice; Michaud, Peter

    2012-08-01

    Currently in its 7th year (2011) Hawaii's annual Journey through the Universe (JttU) program is a flagship Gemini Observatory public education/outreach initiative involving a broad cross-section of the local Hawai'i Island astronomical community, the public, educators, businesses, local government officials, and thousands of local students. This paper describes the program, its history, planning, implementation, as well as the program's objectives and philosophy. The success of this program is documented here, as measured by continuous and expanding engagement of educators, the community, and the public, along with formal evaluation feedback and selected informal verbal testimony. The program's success also serves as justification for the planned adaptation of a version of the program in Chile in 2011 (adapted for Chilean educational and cultural differences). Finally, lessons learned are shared which have refined the program for Gemini's host communities but can also apply to any institution wishing to initiate a similar program.

  6. Gemini's instrumentation program: latest results and long-range plan

    NASA Astrophysics Data System (ADS)

    Boccas, Maxime; Kleinman, S. J.; Goodsell, Stephen; Tollestrup, Eric; Adamson, Andrew; Arriagada, Gustavo; Christou, Julian; Gonzalez, Patricio; Hanna, Kevin; Hartung, Markus; Lazo, Manuel; Mason, Rachel; Neichel, Benoît; Perez, Gabriel; Simons, Doug; Walls, Brian; White, John

    2012-09-01

    The Gemini Observatory is going through an extraordinary time with astronomical instrumentation. New powerful capabilities are delivered and are soon entering scientific operations. In parallel, new instruments are being planned and designed to align the strategy with community needs and enhance the competitiveness of the Observatory for the next decade. We will give a broad overview of the instrumentation program, focusing on achievements, challenges and strategies within a scientific, technical and management perspective. In particular we will discuss the following instruments and projects (some will have dedicated detailed papers in this conference): GMOS-CCD refurbishment, FLAMINGOS-2, GeMS (MCAO system and imager GSAOI), GPI, new generation of A&G, GRACES (fiber feed to CFHT ESPaDOnS) and GHOS (Gemini High-resolution Optical Spectrograph), and provide some updates about detector controllers, mid-IR instruments, Altair, GNIRS, GLAO and future workhorse instruments.

  7. Observations of Beta Pictoris b with the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Chilcote, J.; Graham, J.; Barman, T.; Fitzgerald, M.; Larkin, J.; Macintosh, B.; Bauman, B.; Burrows, A.; Cardwell, A.; De Rosa, R.; Dillon, D.; Doyon, R.; Dunn, J.; Erikson, D.; Gavel, D.; Goodsell, S.; Hartung, M.; Hibon, P.; Ingraham, P.; Kalas, P.; Konopacky, Q.; Maire, J.; Marchis, F.; Marley, M.; Mcbride, J.; Millar-Blanchaer, M.; Morzinski, K.; Norton, A.; Oppenheimer, B.; Palmer, D.; Patience, J.; Pueyo, L.; Rantakyro, F.; Sadakuni, N.; Saddlemyer, L.; Savransky, D.; Serio, A.; Soummer, R.; Sivaramakrishnan, A.; Song, I.; Thomas, S.; Wallace, K.; Wiktorowicz, S.; Wolff, S.

    2014-09-01

    Using the recently installed Gemini Planet Imager (GPI), we present measurements of the planetary companion to the nearby young star beta Pic. GPI is a facility class instrument located at Gemini South designed to image and provide low-resolution spectra of Jupiter sized, self-luminous planetary companions around young nearby stars. We present the current imaged spectrum and atmospheric models of the planet based upon GPI's R ˜50 integral field spectrograph. Further, we present a joint analysis of the GPI and NACO astrometry, and the Snellen et al. (2014) radial velocity measurement of beta Pic b that provides the first constraint on the argument of periastron, providing a causal link to the infalling, evaporating bodies.

  8. Gemini 8 crew stands on deck of recovery vessel

    NASA Technical Reports Server (NTRS)

    1966-01-01

    The Gemini 8 crew stands on the deck of the recovery vessel, the U.S.S. Leonard F. Mason, with three U.S. Air Force pararescue men. Left to right (standing) are Astronaut Neil A. Armstrong, command pilot; A/2C Glenn M. Moore; Astronaut David R. Scott, pilot; kneeling, left to right are A/1C Eldridge M. Neal; and S/Sgt Larry D. Huyett.

  9. Gemini's protected silver coatings: first two years in operation

    NASA Astrophysics Data System (ADS)

    Vucina, Tomislav; Boccas, Maxime; Araya, Claudio; Ahhee, Clayton

    2006-06-01

    The Gemini twins were the first large modern telescopes to receive protected Silver coatings on their mirrors in 2004. We report the performance evolution of these 4-layer coatings in terms of reflectivity and emissivity. We evaluate the durability of these thin films by comparison to the evolution of some samples that we have produced and exposed since 2002. Finally, we will explain our maintenance plan.

  10. Methyl bromide emissions from tarped fields

    SciTech Connect

    Cicerone, R.J.; Williams, J.; Wang, N.Y.

    1995-12-31

    Once in the stratosphere, bromine atoms can destroy ozone effectively. Because of this potential effect, certain organobromine compounds including methyl bromide (MeBr) are being controlled or eliminated by national and international regulations. It would be valuable to determine the fraction of MeBr used in soil fumigations that subsequently enters the atmosphere to better assess the need for, and value of, strong regulations. We have designed and conducted several experiments accompanying field fumigations with MeBr/chloropicrin mixtures. In each of three field-fumigation experiments new Irvine, CA in which the fumigated field was covered immediately with plastic tarping, we have deployed static flux chambers on top of the tarping and measured escape fluxes of MeBr. After tarp removal, the same chambers were replaced on the bare soil to continue the measurements. We have also measured soil bromide contents before and after the fumigation. One experiment yielded an escape fraction of 80 to 87% (with 19% remaining as bromide) while the other two experiments yielded escape fractions of 30 to 35% (with about 70% remaining as bromide). This paper will summarize stratospheric bromine chemistry, describe the field experiments and discuss factors that influence emissions, including soil pH, moisture and organic content and injection technique. We acknowledge TriCal, Inc. for many helpful discussions and for professional field applications of MeBr.

  11. 77 FR 35295 - Methyl Bromide; Pesticide Tolerances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    .... Background In the Federal Register of April 6, 2012 (77 FR 20752) (FRL-9345- 1), EPA issued a proposed rule... methyl bromide in or on cotton, undelinted seed under the Federal Food, Drug, and Cosmetic Act (FFDCA... on cotton, undelinted seed at 150 parts per million (ppm). EPA issued a proposed rule that...

  12. Zinc Bromide Waste Solution Treatment Options

    SciTech Connect

    Langston, C.A.

    2001-01-16

    The objective of this effort was to identify treatment options for 20,000 gallons of low-level radioactively contaminated zinc bromide solution currently stored in C-Area. These options will be relevant when the solutions are declared waste.

  13. Can Georgia growers replace methyl bromide

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The price and availability of methyl bromide is limiting its use on Georgia farms; the need for an alternative is essential for sustainable vegetable production in GA. Three alternatives were evaluated in on-farm trials in the spring 2007 in Tift, Colquitt and Echols Counties. Treatments were replic...

  14. On the Shoulders of Titans: A History of Project Gemini

    NASA Technical Reports Server (NTRS)

    Hacker, B. C.

    1977-01-01

    Gemini was the intermediate manned space flight program between America's first steps into space with Mercury and the manned lunar expeditions of Apollo. Because of its position between these two other efforts, Gemini is probably less remembered. Still, it more than had its place in man's progress into this new frontier. Gemini accomplishments were manyfold. They included many firsts: first astronaut-controlled maneuvering in space; first rendezvous in space of one spacecraft with another; first docking of one spacecraft with a propulsive stage and use of that stage to transfer man to high altitude; first traverse of man into the earth's radiation belts; first extended manned flights of a week or more in duration; first extended stays of man outside his spacecraft; first controlled reentry and precision landing; and many more. These achievements were significant in ways one cannot truly evaluate even today, but two things stand out: (1) it was the time when America caught up and surpassed the Soviet Union in manned space flight, and (2) these demonstrations of capability were an absolute prerequisite to the phenomenal Apollo accomplishments then yet to come.

  15. Gemini - John W. Young in Rendezvous Docking Simulator

    NASA Technical Reports Server (NTRS)

    1963-01-01

    Astronaut John Young (above) was one of 14 astronauts, 8 NASA test pilots, and 2 McDonnell test pilots who took part in simulator studies. Young piloted the simulator on November 12, 1963 Arthur Vogeley wrote: 'Many of the astronauts have flown this simulator in support of the Gemini studies and they, without exception, appreciated the realism of the visual scene. The simulator has also been used in the development of pilot techniques to handle certain jet malfunctions in order that aborts could be avoided. In these situations large attitude changes are sometimes necessary and the false motion cues that were generated due to earth gravity were somewhat objectionable; however, the pilots were readily able to overlook these false motion cues in favor of the visual realism.' Roy F. Brissenden wrote:'The basic Gemini control studies developed the necessary techniques and demonstrated the ability of human pilots to perform final space docking with the specified Gemini-Agena systems using only visual references. ... Results... showed that trained astronauts can effect the docking with direct acceleration control and even with jet malfunctions as long as good visual conditions exist.... Probably more important than data results was the early confidence that the astronauts themselves gained in their ability to perform the maneuver in the ultimate flight mission.'

  16. A Virtual Field Trip to the Gemini Observatory

    NASA Astrophysics Data System (ADS)

    Fisher, R. Scott; Michaud, P. D.

    2010-01-01

    Live from Gemini (LfG) is a virtual field trip using video conferencing technology to connect primary, secondary and post-secondary students with scientists and educators at the Gemini Observatory. As a pilot project, LfG is rapidly becoming one of the observatory's most often-requested educational programs for learners of all ages. The program aligns exceptionally well with national science (and technology) standards, as well as existing school curricula. This combination makes it easy for teachers to justify participation in the program, especially as the necessary video conferencing technology becomes ever more ubiquitous in classrooms and technology learning centers around the world. In developing and testing this pilot project, a programmatic approach and philosophy evolved that includes post-field-trip educational materials, multi-disciplinary subject matter (astronomy, geology, mathematics, meteorology, engineering and even language - the program is offered in Spanish from Gemini South in Chile), and the establishment of a personal connection and rapport with students. The presenters work to create a comfortable interaction despite the perceived technological barriers. The authors’ experiences with the LfG pilot project convince us that this model is viable for almost any astronomical observatory and should be considered by any dynamic, technology- and education-oriented facility.

  17. Easier Phase IIs: Recent Improvements to the Gemini User Tools

    NASA Astrophysics Data System (ADS)

    Miller, Bryan; Nuñez, A.

    2013-01-01

    During 2011 and 2012 Gemini Observatory undertook a significant project to improve the software tools used by investigators to propose for and prepare observations. The main goal was to make the definition of observation details (the Phase II process) easier and faster. The main initiatives included rewriting the observing proposal tool (Phase I Tool) and making several major improvements to the Observing Tool, including automatic settings for arc and flat exposures, automatic guide star selection for all instruments and wavefront sensors, and more complete initial template observations with capabilities for simultaneous editing of many observations. This poster explains these major changes as well as outlines future development plans. The Gemini Observatory is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the Science and Technology Facilities Council (United Kingdom), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência, Tecnologia e Inovação (Brazil), and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina).

  18. Visible Spectroscopic Observation Of Asteroid 162173 (1999ju3) With The Gemini-s Telescope

    NASA Astrophysics Data System (ADS)

    Sugita, Seiji; Kuroda, D.; Kameda, S.; Hasegawa, S.; Kamata, S.; Abe, M.; Ishiguro, M.; Takato, N.; Yoshikawa, M.

    2012-10-01

    Asteroid 162173 (1999JU3; hereafter JU3) is the target of the Hayabusa-2 mission. Its visible reflectance spectra have been observed a few times [1,2], and obtained spectra exhibit a wide variety of spectral patterns ranging from a spectra with absorption in the UV region (May 1999) to a flat spectrum with a faint broad absorption centered around 0.6 microns (September 2007) and that with UV absorption and strong broad absorption centered around 0.7 micron (July 2007). The apparent large spectral variation may be due to variegation on the asteroid surface. Such variegation would make a large influence on remote sensing strategy for Hayabusa-2 before its sampling operations. In order to better constraint the spectral properties of JU3, we conducted visible spectroscopic observations at the GEMINI-South observatory 8.1-m telescope with the GMOS instrument. We could obtain three different sets of data in June and July 2012. Although the JU3 rotation phases of two of the observation are close to each other, the other is about 120 degrees away from the two. Our preliminary analyses indicate that these three spectra are slightly reddish but generally flat across the observed wavelength range (0.47 - 0.89 microns). The observed flat spectra are most similar to the spectrum obtained in September 2007, which probably has the highest signal-to-noise ratio among the previous three spectra. This result suggests that material with a flat spectrum probably covers a dominant proportion of the JU3 surface and that the other two types of previously obtained spectra may not cover a very large fraction of the JU3 surface. [1] Binzel, R. P. et al. (2001) Icarus, 151, 139-149; [2] Vilas, F. (2008) AJ, 135, 1101-1105.

  19. Gemini 9-A spacecraft touches down in the Atlantic at end of mission

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Gemini 9-A space flight is concluded as the Gemini 9 spacecraft touches down in the Atlantic. In this view its parachute is still deployed as the spacecraft hits the water (34117); Astronauts Thomas Stafford (right) and Eugene Cernan wave to the crowd aboard the aircraft carrier U.S.S. Wasp as they emerge from their Gemini 9 capsule. John C. Stonesifer (far right), with the Manned Spacecraft Center's Landing and Recovery Division, was on board to greet the astronauts (34118).

  20. A comprehensive study on micellization of dissymmetric pyrrolidinium headgroup-based gemini surfactants.

    PubMed

    Zou, Min; Dong, Jinfeng; Yang, Guangfu; Li, Xuefeng

    2015-04-21

    Three groups of pyrrolidinium headgroup-based gemini surfactants of 1,1'-(propane-1,3-diyl)bis(1-alkyl pyrrolidinium) bromide, in categories of symmetric CmC3CmPB (m = 10, 12, 14), dissymmetric CmC3C14PB (m = 10, 12, 14) and CmC3CnPB (m = 8, 10, 12, m + n = 24) surfactants, are studied using equilibrium surface tension, conductivity, fluorescence, and NMR techniques. The importance of the dissymmetry on the micellization has been revealed in detail. The increase in the hydrophobic chain length m for CmC3CmPB and CmC3C14PB or in the dissymmetry (n/m) for CmC3CnPB can strengthen the aggregation ability and surface activity of the surfactants significantly, i.e., a lower critical micelle concentration (cmc) and a lower surface tension at cmc (γcmc). However, the aggregation number at cmc (N*) obeys the opposite variation tendency and it becomes smaller upon increasing m or n/m, due to the formation of premicelles. Thermodynamic results reveal that the contribution of enthalpy (ΔH) to the Gibbs free energy (ΔG) is strengthened by increasing m or n/m during the spontaneous micellization process. Moreover, (1)H NMR results confirm the microenvironment change of the surfactants from polar water to micelles during the micellization, and 2D Noesy NMR spectra suggest that the methylene groups in the ring should adopt a conformation toward the nonpolar micellar core rather than in the polar water.

  1. A comparison of the action of otilonium bromide and pinaverium bromide: study conducted under clinical control.

    PubMed

    Defrance, P; Casini, A

    1991-11-01

    We studied 40 patients with irritable bowel syndrome (IBS) which received in a simple-blind fashion otilonium and pinaverium bromide (15 days each drug). During each 15-day period we evaluated: number of pain episodes, intensity of pain, number of bowel movements, side effects. Otilonium bromide, (OB), compared with pinaverium bromide was able to significantly (p less than 0.05) reduce the number of pain attacks, whereas no significant differences were found between the 2 groups as regards the other parameters. The occurrence of side effects was similar in the two treatment courses. We can conclude that the two types of treatment were similarly useful in IBS, although OB seems more effective than pinaverium bromide. PMID:1756286

  2. Novel Synthesis of Anionic Gemini Surfactants from 1, 4-Diol as a Key Block Material.

    PubMed

    Kawase, Tokuzo; Nakagawa, Mami; Higuchi, Yuuya; Oida, Tatsuo

    2015-01-01

    In this study, a series of all-hydrocarbon anionic gemini surfactants containing COOH (adipic acid-type and suberic acid-type), SO3Na, OSO3Na, and OP=O(OH)2 functional groups was developed from 1,4-diol and 1,4-diketone as a key block material. The effect of the surfactant head groups on the surface properties was investigated by surface tension and surface pressure-area (π-A) measurements. We found that the critical micelle concentrations (CMC) of the studied geminis were smaller by one order of magnitude than those of the corresponding 1+l-type surfactants. From π-A measurements, the limiting areas of COOH-type geminis were less than twofold of the area of the corresponding 1+1-type, which indicates that the gemini structure enabled tighter packing than is possible in surfactants of the 1+l-type. In contrast, the limiting area of the OP=O(OH)2-type gemini was larger than those of the COOH-type geminis. Furthermore, the suberic acid-type gemini showed a smaller limiting area than that of adipic acid-type gemini. Therefore, we can conclude that the flexibility of the gemini at the connecting position has a significant effect on formation of the monolayer at the air/water interface.

  3. Flow injection determination of bromide ion in a developer using bromide ion-selective electrode detector.

    PubMed

    Masadome, T; Asano, Y; Nakamura, T

    1999-10-01

    A potentiometric flow injection determination method for bromide ion in a developer was proposed, by utilizing a flow-through type bromide ion-selective electrode detector. The sensing membrane of the electrode was Ag(2)S-AgBr membrane. The response of the electrode detector as a peak-shape signal was obtained for injected bromide ion in a developer. A linear relationship was found to exist between peak height and the concentration of the bromide ion in a developer in a concentration range from 1.0x10(-3) to 1.0x10(-2) mol l(-1). The relative standard deviation for 10 injections of a 6x10(-3) mol l(-1) bromide ion in a developer was 1.3% and the sampling rate was ca 17-20 samples h(-1). The present method was free from the interference of an organic reducing reagent, an organic substance in a developer sample solution for the determination of bromide ion in a developer.

  4. 21 CFR 522.275 - N-Butylscopolammonium bromide.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 6 2013-04-01 2013-04-01 false N-Butylscopolammonium bromide. 522.275 Section 522....275 N-Butylscopolammonium bromide. (a) Specifications. Each milliliter of solution contains 20 milligrams (mg) N-butylscopolammonium bromide. (b) Sponsor. See No. 000010 in § 510.600(c) of this...

  5. 21 CFR 522.275 - N-Butylscopolammonium bromide.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 6 2012-04-01 2012-04-01 false N-Butylscopolammonium bromide. 522.275 Section 522....275 N-Butylscopolammonium bromide. (a) Specifications. Each milliliter of solution contains 20 milligrams (mg) N-butylscopolammonium bromide. (b) Sponsor. See No. 000010 in § 510.600(c) of this...

  6. 40 CFR 180.124 - Methyl bromide; tolerances for residues.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Methyl bromide; tolerances for... § 180.124 Methyl bromide; tolerances for residues. (a) General. A tolerance is established for residues of the fumigant methyl bromide, including metabolites and degradates, in or on the commodity in...

  7. 21 CFR 522.275 - N-Butylscopolammonium bromide.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false N-Butylscopolammonium bromide. 522.275 Section 522....275 N-Butylscopolammonium bromide. (a) Specifications. Each milliliter of solution contains 20 milligrams (mg) N-butylscopolammonium bromide. (b) Sponsor. See No. 000010 in § 510.600(c) of this...

  8. 21 CFR 522.275 - N-Butylscopolammonium bromide.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 6 2011-04-01 2011-04-01 false N-Butylscopolammonium bromide. 522.275 Section 522....275 N-Butylscopolammonium bromide. (a) Specifications. Each milliliter of solution contains 20 milligrams (mg) N-butylscopolammonium bromide. (b) Sponsor. See No. 000010 in § 510.600(c) of this...

  9. Measurements of atmospheric methyl bromide and bromoform

    SciTech Connect

    Cicerone, R.J.; Heidt, L.E.; Pollock, W.H.

    1988-04-20

    We have measured gaseous methyl bromide (CH/sub 3/Br) and bromoform (CHBr/sub 3/) in air samples that were gathered approximately weekly from five ground-level sites: Point Barrow, Alaska; Mauna Loa Observatory and Cape Kumukahi, Hawaii; Matatula, Samoa; and Kaitorete Spit, New Zealand. Approximately 750 samples have been analyzed for CH/sub 3/Br between January 1985 and October 1987 and 990 samples have been analyzed for CHBr/sub 3/ between early 1984 and September 1987, all by gas chromatography/mass spectroscopy. Methyl bromide concentrations are typically 10--11 parts per trillion (ppt) by volume; there are no clear indications of temporal increases. Bromoform concentrations are typically 2--3 ppt, but large seasonal variations are seen at Point Barrow. copyright American Geophysical Union 1988

  10. Methyl bromide users search for science

    SciTech Connect

    Winegar, E.D.

    1995-01-01

    Workers, neighbors and the ozone are protected by regulation from this chemical, but those needing it complain that a solid foundation is lacking for the rules. Although not yet featured on {open_quotes}60 Minutes,{close_quotes} the pesticide methyl bromide is gaining widespread attention because of its central position in debates about worker health and safety, environmental toxics exposure and global ozone depletion.

  11. Removal of bromide and natural organic matter by anion exchange.

    PubMed

    Hsu, Susan; Singer, Philip C

    2010-04-01

    Bromide removal by anion exchange was explored for various water qualities, process configurations, and resin characteristics. Simulated natural waters containing different amounts of natural organic matter (NOM), bicarbonate, chloride, and bromide were treated with a polyacrylate-based magnetic ion exchange (MIEX) resin on a batch basis to evaluate the effectiveness of the resin for removal of bromide. While bromide removal was achieved to some degree, alkalinity (bicarbonate), dissolved organic carbon (DOC), and chloride were shown to inhibit bromide removal in waters with bromide concentrations of 100 and 300 microg/L. Water was also treated using a two-stage batch MIEX process. Two-stage treatment resulted in only a slight improvement in bromide removal compared to single-stage treatment, presumably due to competition with the high concentration of chloride which is present along with bromide in natural waters. In view of the relatively poor bromide removal results for the MIEX resin, a limited set of experiments was performed using polystyrene resins. DOC and bromide removal were compared by treating model waters with MIEX and two polystyrene resins, Ionac A-641 and Amberlite IRA910. The two polystyrene resins were seen to be more effective for bromide removal, while the MIEX resin was more effective at removing DOC.

  12. [Research advances in methyl bromide in the ocean].

    PubMed

    Du, Hui-na; Xie, Wen-xia; Cui, Yu-qian; Chen, Jian-lei; Ye, Si-yuan

    2014-12-01

    Methyl bromide is an important atmospheric trace gas, which plays significant roles in the global warming and atmospheric chemistry. The ocean plays important and complex roles in the global biogeochemical cycles of methyl bromide, not only the source of atmospheric methyl bromide, but also the sink. Therefore, developing the chemical research of the soluble methyl bromide in the ocean, will not only have a certain guiding significance to the atmospheric ozone layer protection, but also provide a theoretical basis for estimating methyl bromide's contribution to the global environmental change on global scale. This paper reviewed the research advances on methyl bromide in the ocean, from the aspects of the biogeochemical cycle of methyl bromide in the ocean, the analysis and determination method, the concentration distribution, the sea-to-air flux and its sources and sinks in the atmosphere. Some deficiencies in the current studies were put forward, and the directions of the future studies were prospected. PMID:25876424

  13. [Research advances in methyl bromide in the ocean].

    PubMed

    Du, Hui-na; Xie, Wen-xia; Cui, Yu-qian; Chen, Jian-lei; Ye, Si-yuan

    2014-12-01

    Methyl bromide is an important atmospheric trace gas, which plays significant roles in the global warming and atmospheric chemistry. The ocean plays important and complex roles in the global biogeochemical cycles of methyl bromide, not only the source of atmospheric methyl bromide, but also the sink. Therefore, developing the chemical research of the soluble methyl bromide in the ocean, will not only have a certain guiding significance to the atmospheric ozone layer protection, but also provide a theoretical basis for estimating methyl bromide's contribution to the global environmental change on global scale. This paper reviewed the research advances on methyl bromide in the ocean, from the aspects of the biogeochemical cycle of methyl bromide in the ocean, the analysis and determination method, the concentration distribution, the sea-to-air flux and its sources and sinks in the atmosphere. Some deficiencies in the current studies were put forward, and the directions of the future studies were prospected.

  14. Methyl bromide: Ocean sources, ocean sinks, and climate sensitivity

    SciTech Connect

    Anbar, A.D.; Yung, Y.L.; Chavez, F.P.

    1996-03-01

    This study was performed to examine conflicting conclusions of two previously published studies which estimated the size of oceanic sources of methyl bromide. In addition, the sensitivity of atmospheric methyl bromide to climatic variations was examined. A steady state mass balance model was used to reexamine data from the previous studies. Linear scaling of methyl bromide production rates to chlorophyll content provided agreement between the two models. The results suggest that the open ocean is a small net sink for atmospheric methyl bromide, rather than a large net source. A high rate of biological production of methyl bromide in seawater is also strongly indicated. A coupled ocean-atmosphere model indicated that methyl bromide variations induced by climatic change can be larger than those resulting from 25% variations in anthropogenic sources. Quantifying marine production rates of methyl bromide is suggested as a necessary step in assessing stratospheric ozone loss. 63 refs., 10 figs., 2 tabs.

  15. Methyl bromide volatility measurements from treated fields

    SciTech Connect

    Majewski, M.S.; Woodrow, J.E.; Seiber, J.N. |

    1995-12-31

    Methyl bromide is used as an agricultural soil fumigant and concern is growing over the role it may play in the depletion of stratospheric ozone. Methyl bromide is applied using various techniques and little is known about how much of the applied fumigant volatilizes into the atmosphere after application. The post-application volatilization losses of methyl bromide from two fields using different application practices were measured using an aerodynamic-gradient technique. One field was covered with a high-barrier plastic film tarp during application and the other was left uncovered, but the furrows made by the injection shanks were bedded over. The cumulative volatilization losses from the tarped field were 22% of the nominal application within the first 5 days of the experiment and about 32% of the nominal application within 9 days including the one day after the tarp was removed on day 8. The nontarped field lost 89%of the nominal application by volatilization in 5 days. The error associated, with each flux measurement, as well as variations in daily flux losses with differing sampling period lengths show the degree of variability inherent in this type of study.

  16. Methyl bromide fate in fumigated soils

    SciTech Connect

    Anderson, T.A.; Rice, P.J.; Cink, J.H.

    1995-12-31

    Although widespread use of methyl bromide (MeBr) as a sail and structure fumigant has previously been recognized as a potential significant source of atmospheric MeBr, losses have not been well quantified. Our research indicates that, in laboratory studies, MeBr is volatilized rapidly from fumigated soils and that volatility increases with temperature (35{degrees}C > 25{degrees}C and 15{degrees}C) and moisture (0.03 bar and 0.3 bar > 1 bar > 3 bar). Degradation of MeBr in soil, as indicated by production of bromide ion, was also directly related to temperature and moisture. Most of the soil degradation of MeBr in these studies appears to be abiotic based on the observation of toxicity (reduced microbial respiration) in fumigated soils. We also determined the transformation and movement of MeBr in undisturbed soil columns. These studies also indicated that MeBT volatilizes rapidly (> 50% in 48 h) from soil. In addition, MeBr was not detected in the leachate from the soil columns, however, bromide ion was detected at levels above background 48 h after fumigation and peaked at 5 weeks.

  17. Gemini spectra of 12000 K white dwarf stars

    NASA Astrophysics Data System (ADS)

    Kepler, S. O.; Castanheira, B. G.; Costa, A. F. M.; Koester, D.

    2006-11-01

    We report signal-to-noise ratio (S/N) ~= 100 optical spectra for four DA white dwarf stars acquired with the GMOS spectrograph of the 8-m Gemini north telescope. These stars have 18 < g < 19 and are around Teff ~ 12000 K, where the hydrogen lines are close to maximum. Our purpose is to test if the effective temperatures and surface gravities derived from the relatively low-S/N ( ~ 21) optical spectra acquired by the Sloan Digital Sky Survey through model atmosphere fitting are trustworthy. Our spectra range from 3800 to 6000 Å, therefore including Hβ to H9. The H8 line was only marginally present in the SDSS spectra, but is crucial to determine the gravity. When we compare the values published by Kleinman et al. and Eisenstein et al. with our line-profile technique (LPT) fits, the average differences are: ΔTeff ~= 320 K, systematically lower in the SDSS, and Δ log g ~= 0.24 dex, systematically larger in the SDSS. The correlation between the gravity and the effective temperature can only be broken at wavelengths bluer than 3800 Å. The uncertainties in Teff are 60 per cent larger, and in log g larger by a factor of 4, than the internal uncertainties of Kleinman et al. and Eisenstein et al. Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the Particle Physics and Astronomy Research Council (United Kingdom), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), CNPq (Brazil) and CONICET (Argentina). E-mail: kepler@if.ufrgs.br

  18. Giant Micelles of Organoplatinum(II) Gemini Amphiphiles

    PubMed Central

    Maran, Umamageswaran; Conley, Hiram; Frank, Markus; Arif, Atta M.; Orendt, Anita M.; Britt, David; Hlady, Vladimir; Davis, Robert; Stang, Peter J.

    2008-01-01

    Organoplatinum(II) gemini amphiphiles with two different chain lengths are synthesized and characterized. Self-assembly at the air-water interface is investigated as a function of chain length and reduction in surface area by using Langmuir-trough techniques. The Langmuir-trough experiments lead to a conjecture that surface aggregates may be the adsorbing units. Atomic force microscopy on the transferred Langmuir-Schaefer films reveals spontaneous formation of wormlike micellar aggregates. A shear-induced transition and alignment are proposed for the observed effects. PMID:18439034

  19. Participación argentina en el Gemini Observatory

    NASA Astrophysics Data System (ADS)

    Cellone, S. A.; Faifer, F. R.; Smith-Castelli, A. V.; Ferreiro, D.; Ferrero, G.

    Since the beginning of the present century; Argentina has access to two twin telescopes each 8.1m in diameter. The Observatory covers both celestial hemispheres; and is equipped with modern instrumentation spanning from the optical to the mid-infrared. This paper gives a brief description of present instruments as well as those available in the near future; pointing to their possible impact on different research lines. The present situation of the Argentine participation in Gemini is illustrated with a few relevant statistical data; focusing the attention on the new agreement that should be signed by all the partners in 2015. FULL TEXT IN SPANISH

  20. Characterizing Transiting Exoplanet Atmospheres with Gemini/GMOS: First Results

    NASA Astrophysics Data System (ADS)

    Huitson, Catherine; Desert, Jean-Michel; Bean, Jacob; Fortney, Jonathan J.; Stevenson, Kevin B.; Bergmann, Marcel

    2015-01-01

    We present the first results from a 4-year ground-based survey of nine transiting exoplanet atmospheres. The program uses the Multi-Object Spectrograph (GMOS) on both Gemini north and south to repetitively measure transit lightcurves of individual exoplanets at high spectrophotometric precision. I will present the first results from this program. We attain photometric precisions per spectral bin of 200-600 ppm. Such precision enables us to construct transmission spectra of hot Jupiters. These transmission spectra reveal the dominant upper-atmosphere absorbers in the optical bandpass. Our overarching goal is to understand the prevalence and formation of high altitude clouds and hazes, and other important atmospheric constituents.

  1. Molecular investigation of the interaction between ionic liquid type gemini surfactant and lysozyme: A spectroscopic and computational approach.

    PubMed

    Maurya, Jitendra Kumar; Mir, Muzaffar Ul Hassan; Singh, Upendra Kumar; Maurya, Neha; Dohare, Neeraj; Patel, Seema; Ali, Anwar; Patel, Rajan

    2015-07-01

    Herein, we are reporting the interaction of ionic liquid type gemini surfactant, 1,4-bis(3-dodecylimidazolium-1-yl) butane bromide ([C12-4-C12 im]Br2) with lysozyme by using Steady state fluorescence, UV-visible, Time resolved fluorescence, Fourier transform-infrared (FT-IR) spectroscopy techniques in combination with molecular modeling and docking method. The steady state fluorescence spectra suggested that the fluorescence of lysozyme was quenched by [C12-4-C12 im]Br2 through static quenching mechanism as confirmed by time resolved fluorescence spectroscopy. The binding constant for lysozyme-[C12-4-C12 im]Br2 interaction have been measured by UV-visible spectroscopy and found to be 2.541 × 10(5) M(-1). The FT-IR results show conformational changes in the secondary structure of lysozyme by the addition of [C12-4-C12 im]Br2. Moreover, the molecular docking study suggested that hydrogen bonding and hydrophobic interactions play a key role in the protein-surfactant binding. Additionally, the molecular dynamic simulation results revealed that the lysozyme-[C12-4-C12 im]Br2 complex reaches an equilibrium state at around 3 ns.

  2. Synthesis of Multibranched Gold Nanoechinus Using a Gemini Cationic Surfactant and Its Application for Surface Enhanced Raman Scattering.

    PubMed

    Vijayaraghavan, Priya; Liu, Cheng-Hong; Hwang, Kuo Chu

    2016-09-14

    High-yield multibranched Au nanoechinus possessing lengthy and dense branched nanorods on the surface were synthesized using a seed-mediated surfactant-directed approach in the presence of gemini cationic surfactant N,N,N'N'-tetramethyl-N,N'-ditetradecylethane-1,2-diaminium bromide (C14C2C14Br2), HAuCl4, AgNO3, and ascorbic acid. C14C2C14Br2 surfactant provides a versatile template in designing the unique morphology of Au nanoechinus with the assistance of AgNO3. UV-vis spectroscopic analysis proves that Au nanoechinus possess a unique intense broad localized surface plasmon resonance (LSPR) peak, which extends from 400 to 1700 nm in the NIR region making a highly potential platform for biomedical applications. Systematic time-dependent TEM, UV-vis-NIR, and XRD analysis were performed to monitor the morphological evolution of multibranched Au nanoechinus. It was found that the surface of branched nanorods of Au NE preferentially grew along (111) crystal planes. Furthermore, as-synthesized Au nanoechinus shows excellent SERS enhancement ability for dopamine inside HeLa cells. PMID:27556284

  3. Integral field spectroscopy with the Gemini Near-Infrared Spectrograph

    NASA Astrophysics Data System (ADS)

    Allington-Smith, Jeremy R.; Dubbeldam, Cornelis M.; Content, Robert; Dunlop, Colin J.; Robertson, David J.; Elias, Jay; Rodgers, Bernadette; Turner, James E.

    2004-09-01

    The Astronomical Instrumentation Group (AIG) of the University of Durham has recently completed an integral field unit (IFU) for use on the Gemini-South telescope with the Gemini Near-Infrared Spectrograph (GNIRS) built by the National Optical Astronomy Observatories (NOAO, USA). When the IFU is deployed remotely inside the instrument cryostat, GNIRS is converted into an integral field spectrograph with a field of 5 × 3 arcsec2 and spatial sampling of 0.15 × 0.15 arcsec2, optimised for 1-2.5μm but operable up to 5μm. We present summaries of the design and construction and results from laboratory testing. We also show results obtained at the telescope where a throughput of 90% was measured at 2.5μm, and show that this is consistent with predictions of a simple model where surface scattering is the dominant loss mechanism. The throughput data are well fit by the roughness measured in the laboratory. Finally, we show a few examples of astrophysical data from the commissioning run in April 2004.

  4. Gemini Planet Imager: From Integration And Test To Planning Observations

    NASA Astrophysics Data System (ADS)

    Thomas, Sandrine; Macintosh, B.; Palmer, D.; Saddlemyer, L.; Wallace, J. K.; Gavel, D.; Larkin, J.; Graham, J.; Doyon, R.; Oppenheimer, B.; GOODSell, S.; GPI Team

    2012-01-01

    Achieving higher contrast is an ongoing theme in exoplanet imaging, both from earth and from space. Next-generation instruments such as the Gemini Planet Imager and SPHERE are designed to achieve contrast ratios of 106 - 107 from the ground; this requires very good static and dynamic wavefront correction as well as very good coronagraphic control of diffraction. GPI is a facility instrument, now in integration and test at the Laboratory for Adaptive Optics in Santa Cruz California. Its first light on the 8-m Gemini South telescope is expected by the end of 2012. GPI combines a high density MEMS deformable mirror (1700 subapertures), an apodized-pupil Lyot coronagraph and a high-accuracy IR interferometer calibration system. The instrument is a near-infrared integral field spectrograph (IFS) that will allow detection and characterization of self-luminous extrasolar planets at planet/star contrast ratios of 10-7. One additional feature of the IFS is a polarimetric mode to characterize scattered light from disks. We will discuss the status of the integration and test happening at the University of Santa Cruz California and discuss its scientific capabilities.

  5. Test results for the Gemini Planet Imager data reduction pipeline

    NASA Astrophysics Data System (ADS)

    Maire, Jérôme; Perrin, Marshall D.; Doyon, René; Chilcote, Jeffrey; Larkin, James E.; Weiss, Jason L.; Marois, Christian; Konopacky, Quinn M.; Millar-Blanchaer, Maxwell; Graham, James R.; Dunn, Jennifer; Galicher, Raphael; Marchis, Franck; Wiktorowicz, Sloane J.; Labrie, Kathleen; Thomas, Sandrine J.; Goodsell, Stephen J.; Rantakyro, Fredrik T.; Palmer, David W.; Macintosh, Bruce A.

    2012-09-01

    The Gemini Planet Imager (GPI) is a new facility instrument for the Gemini Observatory designed to detect and characterize planets and debris disks orbiting nearby stars; its science camera is a near infrared integral field spectrograph. We have developed a data pipeline for this instrument, which will be made publicly available to the community. The GPI data reduction pipeline (DRP) incorporates all necessary image reduction and calibration steps for high contrast imaging in both the spectral and polarimetric modes, including datacube generation, wavelength solution, astrometric and photometric calibrations, and speckle suppression via ADI and SSDI algorithms. It is implemented in IDL as a flexible modular system, and includes both command line and graphical interface tools including a customized viewer for GPI datacubes. This GPI data reduction pipeline is currently working very well, and is in use daily processing data during the instrument’s ongoing integration and test period at UC Santa Cruz. Here we summarize the results from recent pipeline tests, and present reductions of instrument test data taken with GPI. We will continue to refine and improve these tools throughout the rest of GPI’s testing and commissioning, and they will be released to the community, including both IDL source code and compiled versions that can be used without an IDL license.

  6. The Astrometric Calibration of the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Tran, Debby; Konopacky, Quinn; GPIES Collaboration

    2016-06-01

    The Gemini Planet Imager (GPI), housed on the 8-meter Gemini South telescope in Chile, is an instrument designed to detect Jupiter-like extrasolar planets by direct imaging. It relies on adaptive optics to correct the effects of atmospheric turbulence, along with an advanced coronagraph and calibration system. One of the scientific goals of GPI is to measure the orbital properties of the planets it discovers. Because these orbits have long periods, precise measurements of the relative position between the star and the planet (relative astrometry) are required. In this poster, I will present the astrometric calibration of GPI. We constrain the plate scale and orientation of the camera by observing different binary star systems with both GPI and another well-calibrated instrument, NIRC2, at the Keck telescope in Hawaii. We measure their separations with both instruments and use that information to calibrate the plate scale. By taking these calibration measurements over the course of one year, we have measured the plate scale to 0.05% and shown that it is stable across multiple epochs. I will also discuss our effort to correct for optical distortion using pinhole masks in the laboratory.

  7. Point spread function reconstruction on the Gemini Canopus bench

    NASA Astrophysics Data System (ADS)

    Gilles, Luc; Neichel, Benoit; Veran, Jean-Pierre; Ellerbroek, Brent

    2013-12-01

    This paper discusses an open loop, single-conjugate, point spread function reconstruction experiment performed with a bright calibration source and synthetic turbulence injected on the ground-level deformable mirror of the Multi Conjugate Adaptive Optics Canopus bench at Gemini South. Time histories of high-order Shack-Hartmann wavefront sensor slopes were recorded on the telemetry circular buffer, and time histories of short exposure K-band point spread functions with and without turbulence injected were recorded with the Gemini South Adaptive Optics Imager. We discuss the processing of the data and show that the long exposure background- and tip/tilt-removed turbulence image can be reconstructed at a percent level accuracy from the tip/tilt-removed de-noised wavefront sensor slope covariance matrix and from the long exposure background- and tip/tilt-removed static image. Future experiments are planned with multiple calibration sources at infinite and finite range and turbulence injected on 2 deformable mirrors, aiming at validating the recently published point spread function reconstruction algorithm [Gilles et. al. Appl. Opt. 51, 7443 (2012)] for closed loop laser guide star multi-conjugate adaptive optics.

  8. Europium-doped barium bromide iodide

    SciTech Connect

    Gundiah, Gautam; Hanrahan, Stephen M.; Hollander, Fredrick J.; Bourret-Courchesne, Edith D.

    2009-10-21

    Single crystals of Ba0.96Eu0.04BrI (barium europium bromide iodide) were grown by the Bridgman technique. The title compound adopts the ordered PbCl2 structure [Braekken (1932). Z. Kristallogr. 83, 222-282]. All atoms occupy the fourfold special positions (4c, site symmetry m) of the space group Pnma with a statistical distribution of Ba and Eu. They lie on the mirror planes, perpendicular to the b axis at y = +-0.25. Each cation is coordinated by nine anions in a tricapped trigonal prismatic arrangement.

  9. Advanced hydrogen electrode for hydrogen-bromide battery

    NASA Technical Reports Server (NTRS)

    Kosek, Jack A.; Laconti, Anthony B.

    1987-01-01

    Binary platinum alloys are being developed as hydrogen electrocatalysts for use in a hydrogen bromide battery system. These alloys were varied in terms of alloy component mole ratio and heat treatment temperature. Electrocatalyst evaluation, performed in the absence and presence of bromide ion, includes floating half cell polarization studies, electrochemical surface area measurements, X ray diffraction analysis, scanning electron microscopy analysis and corrosion measurements. Results obtained to date indicate a platinum rich alloy has the best tolerance to bromide ion poisoning.

  10. The Gemini Science User Support Department: A community-centered approach to user support

    NASA Astrophysics Data System (ADS)

    Chené, André-Nicolas; Thomas-Osip, Joanna

    2016-01-01

    The Gemini Science User Support Department (SUSD) was formed a little more than a year ago to create a collaborative community of users and staff and to consolidate existing post-observing support throughout the observatory for more efficient use of resources as well as better visibility amongst our user community. This poster is an opportunity to exchange ideas about how Gemini can improve your experience while working with the Observatory and present details about new avenues of post-observing support coming soon. We encourage your feedback at any time.Shortly after its creation, the SUSD conducted a complete revision of the communication cycle between Gemini and its community of researchers. The cycle was then revisited from the perspective of an astronomer interested in using Gemini for their research. This exercise led to a series of proposed changes that are currently under development, and the implementation of a sub-selection is expected in 2016, including the following. (1) Email notifications: Gemini users will receive new forms of email communications that are more instructive and tailored to their program. The objective is to direct the users more efficiently toward the useful links and documentation all along the lifecycle of the program, from phaseII to after the data are completely reduced. (2) HelpDesk system: The HelpDesk will become more user-friendly and transparent. (3) Webpages: The organization of the Gemini webpages will be redesigned to optimize navigation; especially for anything regarding more critical periods likes phaseIs and phaseIIs. (4) Data Reduction User Forum: Following recommendations from Gemini users, new capabilities were added to the forum, like email notifications, and a voting system, in order to make it more practical. This forum's objective is to bring the Gemini community together to exchange their ideas, thoughts, questions and solutions about data reduction, a sort of Reddit, StackOverflow or Slashdot for Gemini data.

  11. Upgrade and standardization of real-time software for telescope systems at the Gemini telescopes

    NASA Astrophysics Data System (ADS)

    Rambold, William N.; Gigoux, Pedro; Urrutia, Cristian; Ebbers, Angelic; Taylor, Philip; Rippa, Mathew J.; Rojas, Roberto; Cumming, Tom

    2014-07-01

    The real-time control systems for the Gemini Telescopes were designed and built in the 1990s using state-of-the-art software tools and operating systems of that time. Since these systems are in use every night they have not been kept upto- date and are now obsolete and very labor intensive to support. Gemini is currently engaged in a major upgrade of its telescope control systems. This paper reviews the studies performed to select and develop a new standard operating environment for Gemini real-time systems and the work performed so far in implementing it.

  12. Ceremonies for Gemini 10 crew on the U.S.S. Guadalcanal

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Twelve-year-old Bill Doyle of Virginia Beach, VA., shakes hands with Gemini 10 pilot Michael Collins aboard the recovery ship U.S.S. Guadalcanal. At right is John W. Young, Gemini 10 command pilot. Billy represented 41 youngsters permitted aboard the Guadalcanal to witness the recovery with their Naval fathers or close relatives, marking the first time dependents have been permitted aboard a ship during a Gemini recovery operation. In front of them is a large cake baked by the ship's cooks for the occasion.

  13. Experiment T001: Entry communication on the Gemini 3 mission

    NASA Technical Reports Server (NTRS)

    Schroeder, L. C.; Sims, T. E.; Cuddihy, W. F.

    1971-01-01

    Water addition to the Gemini 3 exhaust plasma was studied to determine its effectiveness in the establishment of communication links during the entry portion of the flight. Attenuation levels were measured with and without water injection at uhf frequencies of 230.4 and 296.8 megahertz and at the C-band frequency of 5690 megahertz. Ultrahigh frequency signals that had been blacked out were restored to significant levels, during early portions of the water-injection sequence, by the high flow rate injection. The C-band signal was enhanced by medium and high flow rate injections during the latter portion of the injection period. The uhf signal recovered during water injection resulted in an antenna pattern that was beamed in the radial direction of injection from the spacecraft. Postflight analysis showed that the uhf recovery data were consistent with injection-penetration theory.

  14. Fan-In Communications On A Cray Gemini Interconnect

    SciTech Connect

    Jones, Terry R; Settlemyer, Bradley W

    2014-01-01

    Using the Cray Gemini interconnect as our platform, we present a study of an important class of communication operations the fan-in communication pattern. By its nature, fan-in communications form hot spots that present significant challenges for any interconnect fabric and communication software stack. Yet despite the inherent challenges, these communication patterns are common in both applications (which often perform reductions and other collective operations that include fan-in communication such as barriers) and system software (where they assume an important role within parallel file systems and other components requiring high-bandwidth or low-latency I/O). Our study determines the effectiveness of differing clientserver fan-in strategies. We describe fan-in performance in terms of aggregate bandwidth in the presence of varying degrees of congestion, as well as several other key attributes. Comparison numbers are presented for the Cray Aries interconnect. Finally, we provide recommended communication strategies based on our findings.

  15. The synthesis and properties of a new nonionic Gemini surfactant

    NASA Astrophysics Data System (ADS)

    Ren, Yanmei; Lv, Tong; Wang, Qi; Tian, Zhenxing

    2010-07-01

    A new Gemini nonionic surfactant was prepared, taking anhydrous glucose, glycol, maleic anhydride, lauric acid as main materials, and the reaction was carried out by three steps. Firstly, glycol glucoside was synthesized by the direct glycosidation of the anhydrous glucose with glycol in the presence of acidic catalyst. The synthesis and the characterization of this have been reported previously.Secondly, reaction intermediate was prepared by ring opening reaction of maleic anhydride with glycol glucoside. The last, primary hydroxyl group in glucose of reaction intermediate was esterified with lauric acid for synthesis of target product. It was analyzed and characterized by IR, 1HNMR and 13CNMR. Besides, the critical micelle concentration (cmc) and the corresponding surface tension of the target product were measured to be 8.87×10-3molL-1 and 20.70mNm-1 (20°C), respectively.

  16. Gemini ester quat surfactants and their biological activity.

    PubMed

    Łuczyński, Jacek; Frąckowiak, Renata; Włoch, Aleksandra; Kleszczyńska, Halina; Witek, Stanisław

    2013-03-01

    Cationic gemini surfactants are an important class of surface-active compounds that exhibit much higher surface activity than their monomeric counterparts. This type of compound architecture lends itself to the compound being easily adsorbed at interfaces and interacting with the cellular membranes of microorganisms. Conventional cationic surfactants have high chemical stability but poor chemical and biological degradability. One of the main approaches to the design of readily biodegradable and environmentally friendly surfactants involves inserting a bond with limited stability into the surfactant molecule to give a cleavable surfactant. The best-known example of such a compound is the family of ester quats, which are cationic surfactants with a labile ester bond inserted into the molecule. As part of this study, a series of gemini ester quat surfactants were synthesized and assayed for their biological activity. Their hemolytic activity and changes in the fluidity and packing order of the lipid polar heads were used as the measures of their biological activity. A clear correlation between the hemolytic activity of the tested compounds and their alkyl chain length was established. It was found that the compounds with a long hydrocarbon chain showed higher activity. Moreover, the compounds with greater spacing between their alkyl chains were more active. This proves that they incorporate more easily into the lipid bilayer of the erythrocyte membrane and affect its properties to a greater extent. A better understanding of the process of cell lysis by surfactants and of their biological activity may assist in developing surfactants with enhanced selectivity and in widening their range of application.

  17. Monolayer behavior of asymmetrical ester-type tartaric gemini amphiphiles.

    PubMed

    Kawase, Tokuzo; Saito, Isao; Oida, Tatsuo

    2013-01-01

    The ester-type asymmetrical tartaric gemini amphiphiles (C(m)-C(n), where m and n are the number of carbon atoms of hydrophobic alkanoyl group, m+n=28) bearing two carboxyl groups and two different alkanoyl groups were prepared from L-tartaric acid, and the pressure-area (π-A) isotherms for a series of asymmetrical tartaric gemini amphiphiles were studied.The π-A isotherms of asymmetrical C(m)-C(n) monolayers were classified into two groups. Group 1: The asymmetry was small (n/m <1.55), and a phase transition of the monolayer from the liquid-expanded to the liquid condensed state, and a subsequent transition to solid phases were observed. Group 2: The asymmetry was large (n/m >1.8), and only liquid-expanded state of the monolayer film was observed. Based on the subphase temperature (T(sub)) dependence of monolayer static elasticity, es, the melting temperature (T(L)) of asymmetrical C(m)-C(n) monolayer was estimated to be T(L) = 31.7°C and 50.6°C for C₁₃-C₁₅ and C₁₂-C₁₆, respectively. Furthermore, assuming that asymmetrical C₁₃-C₁₅ can be viewed as an equimolar mixture of symmetrical 2C₁₃ and 2C₁₅, the temperature dependence of monolayers of 2C₁₃ and 2C₁₅ mixture at various ratios were also studied. As a result, all TL values of 2C14, C₁₃-C₁₅ and an equimolar mixture of 2C₁₃ and 2C₁₅ were almost the same. However, the variation of T(L) with the molar fraction of 2C₁₅ (X(2C15)) was remarkably different from that of solid melting point T(m) with X(2C15).

  18. Final A&T stages of the Gemini Planet Finder

    NASA Astrophysics Data System (ADS)

    Hartung, Markus; Macintosh, Bruce; Poyneer, Lisa; Savransky, Dimitri; Gavel, Donald; Palmer, Dave; Thomas, Sandrine; Dillon, Daren; Chilcote, Jeffrey; Ingraham, Patrick; Sadakuni, Naru; Wallace, Kent; Perrin, Marshall; Marois, Christian; Maire, Jerome; Rantakyro, Fredrik; Hibon, Pascale; Saddlemyer, Les; Goodsell, Stephen

    2013-12-01

    The Gemini Planet Finder (GPI) is currently in its final Acceptance & Testing stages at the University of Santa Cruz, California. GPI is an XAO system based on a tweeter & woofer architecture (43 & 9 actuators across the pupil), with the tweeter being a Boston Michromachines 64^2 MEMS device. The XAO AO system is tightly integrated with a Lyot apodizing coronagraph. Acceptance has started in February 2013. After the conclusive acceptance review shipment is scheduled mid 2013 to ensure readiness for commissioning at the Gemini South telescope on Cerro Pachon, Chile, end of 2013, matching the summer window of the southern hemisphere. According to current estimates the 3 year (~800 allocated hours) planet finding campaign might discover, image, and spectroscopically analyze 20 to 40 new exo-planets.Final acceptance testing of the integrated instrument can always emerge a number of unforeseen challenges as we are eventually using cold chamber and flexure rig installations. The latest developments will be reported. Also, we will give an overview of GPI's lab performance, the interplay between subsystems such as the calibration unit (CAL) with the AO bench. (The CAL principal purpose is to maintain a clean and centered XAO PSF on the coronagraph.) We report on-going optimizations on the AO controler loop to filter vibrations and last but not least achieved contrast performance applying speckle nulling. Furthermore, we will give an outlook of possible but challenging future upgrades as the implementation of a predictive controler or exchanging the conventional 48x48 SH WFS with a pyramid. With the ELT area arising, GPI will proof as a versatile and path-finding testbed for AO technologies on the next generation of ground-based telescopes.

  19. Photochemical studies of alkylammonium molybdates. Part 12. O→Mo charge-transfer triplet-states-initiated self-assembly to {Mo154} ring- and tube-molybdenum-blues

    NASA Astrophysics Data System (ADS)

    Yamase, T.; Prokop, P.; Arai, Y.

    2003-08-01

    The chemically induced dynamic electron-spin-polarization technique is employed in order to investigate the primary steps of the photoredox reaction between polyoxomolybdates and alkylammonium cations as both proton and electron-donors in solutions. An observation of emissive electron-spin-polarization signals of alkylamino radical cations for the photoredox reaction between polyoxomolybdates and alkylammonium cations in solutions reveals that the O→Mo ligand-to-metal charge-transfer triplet states are involved in the transfers of both proton and electron from alkylammonium cation to polyoxomolybdate anions. Prolonged photolysis of aqueous solutions containing [Mo36O112(H2O)16]8-, [iPrNH3]+, and LaCl3 at pH 1.0 leads to formation of two kinds of {Mo154} molybdenum-blues, [Mo28VMo126VIO462H28(H2O)70]·156.5H2O (1) and [iPrNH3]8 [Mo28VMo126VIO458H12(H2O)66]·127H2O (2), which were X-ray crystallographically characterized. The former exhibits the intact car-tire-shaped {Mo154} ring structure (with thickness of about 1.1 nm and with outer- and inner-rings of approximately 3.5- and 2.3-nm diameters, respectively) derived formally from the dehydrated cyclic heptamerization of four-electron reduced building blocks of {Mo22} (≡[Mo4VMo18VIO70H12(H2O)10]) with overall symmetry of D7d. The anion for the latter, [Mo28VMo126VIO458H12(H2O)66]8- (2a), exhibits a nanotube structure of {Mo154} rings, each inner ring of which contains a bis(μ-oxo)-linkaged [MoO2(μ-O)(μ-H2O)MoO2]2+ unit replacing one of seven [Mo(H2O)O2(μ-O)Mo(H2O)O2]2+linker units. The neighboring {Mo154} rings are connected by six Mo-O-Mo bridge between inner-rings consisting of 7 head- and 14 linkers-MoO6 octahedra for each.

  20. Gemini 12 crew receive Official welcome aboard U.S.S. Wasp

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Astronauts James A. Lovell Jr. (left), command pilot, and Edwin E. Aldrin Jr., pilot, receive Official welcome as they arrive aboard the aircraft carrier U.S.S. Wasp after their splashdown at the end of the Gemini 12 mission.

  1. An Ill Wind: Methyl Bromide Use Near California Schools, 1998.

    ERIC Educational Resources Information Center

    Ross, Zev; Walker, Bill

    A California study investigates the use of the toxic pesticide methyl bromide near the state's public schools, explains why proposed safety rules have failed to protect children and others from exposure, and examines regions at particular exposure risk. Study results show an increasing exposure to methyl bromide near schools already at risk while…

  2. 40 CFR 180.124 - Methyl bromide; tolerances for residues.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Methyl bromide; tolerances for residues. 180.124 Section 180.124 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.124 Methyl bromide; tolerances...

  3. 40 CFR 180.124 - Methyl bromide; tolerances for residues.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Methyl bromide; tolerances for residues. 180.124 Section 180.124 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.124 Methyl bromide; tolerances...

  4. Degradation of methyl bromide in anaerobic sediments

    USGS Publications Warehouse

    Oremland, R.S.; Miller, L.G.; Strohmaler, F.E.

    1994-01-01

    Methyl bromide (MeBr) was anaerobically degraded in saltmarsh sediments after reaction with sulfide. The product of this nucleophilic substitution reaction was methanethiol, which underwent further chemical and bacterial reactions to form dimethyl sulfide. These two gases appeared transiently during sediment incubations because they were metabolized by methanogenic and sulfate-reducing bacteria. A second, less significant reaction of MeBr was the exchange with chloride, forming methyl chloride, which was also susceptible to attack by sulfide. Incubation of 14C-labeled methyl iodide as an analogue of MeBr resulted in the formation of 14CH4 and 14CO2 and also indicated that sulfate-reducing bacteria as well as methanogens metabolized the methylated sulfur intermediates. These results suggest that exposed sediments with abundant free sulfide, such as coastal salt-marshes, may constitute a sink for atmospheric MeBr.

  5. Single ion dynamics in molten sodium bromide

    SciTech Connect

    Alcaraz, O.; Trullas, J.; Demmel, F.

    2014-12-28

    We present a study on the single ion dynamics in the molten alkali halide NaBr. Quasielastic neutron scattering was employed to extract the self-diffusion coefficient of the sodium ions at three temperatures. Molecular dynamics simulations using rigid and polarizable ion models have been performed in parallel to extract the sodium and bromide single dynamics and ionic conductivities. Two methods have been employed to derive the ion diffusion, calculating the mean squared displacements and the velocity autocorrelation functions, as well as analysing the increase of the line widths of the self-dynamic structure factors. The sodium diffusion coefficients show a remarkable good agreement between experiment and simulation utilising the polarisable potential.

  6. A new methyl bromide gas generator for inhalation toxicity studies.

    PubMed

    Hori, H; Hyakudo, T; Tanaka, I

    1992-09-01

    A simple generator for methyl bromide gas has been newly developed by us. For inhalation toxicity studies, until now, there have been few generators capable of producing a constant and stable concentration of methyl bromide gas easily because of its high volatility. The principle of this new generator is based on gas-liquid equilibrium. The gas is generated from the surface of liquid methyl bromide in an evaporator made of a Teflon tube. The generator can produce up to 10,000 ppm of methyl bromide gas in a 0.1 m3 exposure chamber, and the concentration of this generated gas is able to be kept within +/- 0.8% over a long period of time. The generator has proved to be useful for investigating the effects of methyl bromide on health in inhalation toxicity studies.

  7. Atmosphere-plant canopy interactions of methyl bromide

    SciTech Connect

    Taylor, G.E. Jr.; Leonard, T.D.; Gustin, M.S.

    1995-12-31

    In the planetary boundary layer, parcels of air containing background and elevated concentrations of methyl bromide commonly pass through plant canopies in managed (agriculture) and natural (forests, grasslands) ecosystems. It is hypothesized that leaf surfaces are a significant sink or methyl bromide on a local and regional scale and that failure to account for this sink results in a significant overestimation of methyl bromide transport to the stratosphere. Using highly controlled environments, studies are investigating the reactivity of leaf surfaces for methyl bromide at elevated and global background concentrations. Estimates of pathway resistances are being calculated and sites of deposition determined. The results indicate that plant canopies are a significant unrecognized sink for methyl bromide in the atmosphere.

  8. Indirect spectrophotometric determination of traces of bromide in water

    USGS Publications Warehouse

    Fishman, M. J.; Skougstad, M.W.

    1963-01-01

    A rapid, accurate, and sensitive indirect spectrophotometric method for the determination of bromide in natural waters is based on the catalytic effect of bromide on the oxidation of iodine to iodate by potassium permanganate in sulfuric acid solution. The method is applicable to concentrations ranging from 1 to 100 ??g. of bromide per liter, but may be modified to extend the concentration range. Most ions commonly occurring in water do not interfere. The standard deviation is 2.9 at bromide concentrations of 100 ??g. per liter and less at lower concentrations. The determination of bromide in samples containing known added amounts gave values ranging from 99 to 105% of the concentration calculated to be present.

  9. Target of Opportunity Observing in Queue Mode at the Gemini North Observatory

    NASA Astrophysics Data System (ADS)

    Roth, Katherine; Price, P.; Gillies, K.; Walker, S.; Miller, B.

    2009-01-01

    The Gemini Observatories primarily operate a multi-instrument queue, with observers selecting observations that are best suited to weather and seeing conditions. Queue operations give higher ranked programs a greater chance for completion than lower ranked programs requesting the same conditions and instrument configuration. Queue observing naturally lends itself to Target of Opportunity (ToO) support since the time required to switch between programs and instruments is very short, and the staff observer is trained to operate all the available instruments and modes. Gemini Observatory has supported pre-approved ToO programs since beginning queue operations, and has implemented a rapid (less than 15 minutes response time) ToO mode since 2005. The rapid response ToO mode has thus far been exclusively utilized by the Gemini community for optical and near-IR follow-up of Gamma Ray Bursts (GRBs), primarily discovered by the Swift satellite. We discuss the ToO implementation at Gemini Observatory including the ToO user interface and the procedures followed by observatory staff astronomers once a ToO trigger is received. We present the statistics of 4 years of rapid ToOs at Gemini North Observatory, and the advances in our understanding of GRBs, their host galaxies and the intergalactic medium that this important mode has enabled. Finally we discuss recent changes in both software and policy to improve standard and rapid ToO support at the Gemini Observatories. The Gemini Observatory is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the Science and Technology Facilities Council (United Kingdom), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciìncia e Tecnologia (Brazil), and SECYT (Argentina)

  10. Hierarchical Structure from the Self-Assembly of Giant Gemini Surfactants in Condensed State

    NASA Astrophysics Data System (ADS)

    Su, Hao; Wang, Zhao; Li, Yiwen; Cheng, Stephen

    2013-03-01

    In the past a few years, a new class of amphiphiles with both asymmetrical shapes and interactions named ``shape amphiphiles'' has been significantly intensified. Recently, a new kind of shape amphiphiles called ``Giant Gemini Surfactants'' consisting of two hydrophilic carboxylic acid-functionalized polyhedral oligomeric silsesquioxane (APOSS) heads and two hydrophobic polystyrene (PS) tails covalently linked via rigid spacers (p-phenylene versus biphenylene) has been successful behavior of giant gemini surfactants. We currently continue to investigate the spacer effects on the self-assembly behaviors of giant gemini surfactants in condensed state by utilizing DCS, SAXS and TEM. Preliminary results showed that giant gemini surfactants with different spacers have diverse phase behaviors. As we use the same 3.2k PS chains, the giant gemini surfactant with p-phenylene spacer showed double gyroid morphology, while the one with biphenylene spacer revealed cylindrical morphology. This study expands the scope of giant gemini surfactants and contributes a lot to the basic physical principles in self-assembly behavior.

  11. Selective oxidation of bromide in wastewater brines from hydraulic fracturing.

    PubMed

    Sun, Mei; Lowry, Gregory V; Gregory, Kelvin B

    2013-07-01

    Brines generated from oil and natural gas production, including flowback water and produced water from hydraulic fracturing of shale gas, may contain elevated concentrations of bromide (~1 g/L). Bromide is a broad concern due to the potential for forming brominated disinfection byproducts (DBPs) during drinking water treatment. Conventional treatment processes for bromide removal is costly and not specific. Selective bromide removal is technically challenging due to the presence of other ions in the brine, especially chloride as high as 30-200 g/L. This study evaluates the ability of solid graphite electrodes to selectively oxidize bromide to bromine in flowback water and produced water from a shale gas operation in Southwestern PA. The bromine can then be outgassed from the solution and recovered, as a process well understood in the bromine industry. This study revealed that bromide may be selectively and rapidly removed from oil and gas brines (~10 h(-1) m(-2) for produced water and ~60 h(-1) m(-2) for flowback water). The electrolysis occurs with a current efficiency between 60 and 90%, and the estimated energy cost is ~6 kJ/g Br. These data are similar to those for the chlor-alkali process that is commonly used for chlorine gas and sodium hydroxide production. The results demonstrate that bromide may be selectively removed from oil and gas brines to create an opportunity for environmental protection and resource recovery.

  12. Polymerizable gemini surfactants at solid/solution interfaces: adsorption and polymerization on melamine formaldehyde particles and capsule fabrication.

    PubMed

    Sakai, Kenichi; Izumi, Keiko; Sakai, Hideki; Abe, Masahiko

    2010-03-15

    Organic capsules have been fabricated via three steps, by using the polymerizable gemini surfactant (1,2-bis(dimethyl(11-methacryloyloxy)undecylammonio) hexane dibromide, PC11-6-11) as a single wall component. In the first fabrication step, the surfactant spontaneously adsorbs on acid-dissolvable melamine formaldehyde (MF) particles in aqueous media. The adsorption isotherm data reveal that the adsorbed amount of PC11-6-11 (per chain) is greater than that of the corresponding monomeric surfactant ((11-methacryloyloxy)undecyltrimethylammonium bromide, PC11), resulting from the greater intermolecular association of PC11-6-11 at the solid/solution interface. The closely packed adsorbed layer of PC11-6-11 provides an opportunity to give a polymer thin film, as a result of in situ photo-polymerization on MF particles (in the second fabrication step) and subsequent acid dissolution of the core MF particles (in the third fabrication step). The dynamic light scattering (DLS) measurements have shown that the apparent hydrodynamic diameter of PC11-6-11 capsules is reversibly changed in response to a change in ionic strength: the increased background electrolyte concentration results in deswelling of the capsules, and vice versa. It seems likely that this swelling/deswelling behavior is primarily driven by the electrostatic interaction between quaternary ammonium groups within the polymerized film. We have also studied the capture and release capabilities of glucose into/from the capsule core and found that (i) glucose is encapsulated into the capsule core at high electrolyte concentrations and (ii) the glucose molecules encapsulated into the core are gradually released when the outer electrolyte solution is replaced by pure water. We believe, therefore, that the PC11-6-11 capsules fabricated here are useful as stimulus-responsive smart vehicles.

  13. Chloride, bromide and iodide scintillators with europium

    DOEpatents

    Zhuravleva, Mariya; Yang, Kan

    2016-09-27

    A halide scintillator material is disclosed where the halide may comprise chloride, bromide or iodide. The material is single-crystalline and has a composition of the general formula ABX.sub.3 where A is an alkali, B is an alkali earth and X is a halide which general composition was investigated. In particular, crystals of the formula ACa.sub.1-yEu.sub.yI.sub.3 where A=K, Rb and Cs were formed as well as crystals of the formula CsA.sub.1-yEu.sub.yX.sub.3 (where A=Ca, Sr, Ba, or a combination thereof and X=Cl, Br or I or a combination thereof) with divalent Europium doping where 0.ltoreq.y.ltoreq.1, and more particularly Eu doping has been studied at one to ten mol %. The disclosed scintillator materials are suitable for making scintillation detectors used in applications such as medical imaging and homeland security.

  14. Design and analysis of the Gemini chain system in dual clutch transmission of automobile

    NASA Astrophysics Data System (ADS)

    Cheng, Yabing; Guo, Haitao; Fu, Zhenming; Wan, Nen; Li, Lei; Wang, Yang

    2015-01-01

    Chain drive system is widely used in the conditions of high-speed, overload, variable speed and load. Many studies are focused on the meshing theory and wear characteristics of chain drive system, but system design, analysis, and noise characteristics of the chain drive system are weak. System design and noise characteristic are studied for a new type Gemini chain of dual-clutch automatic transmission. Based on the meshing theory of silent chain, the design parameters of the Gemini chain system are calculated and the mathematical models and dynamic analysis models of the Gemini chain system are established. Dynamic characteristics of the Gemini chain system is simulated and the contact force of plate and pin, plate and sprockets, the chain tension forces, the transmission error and the stress of plates and pins are analyzed. According to the simulation results of the Gemini chain system, the noise experiment about system is carried out. The noise values are tested at different speed and load and spectral characteristics are analyzed. The results of simulation and experimental show that the contact forces of plate and pin, plate and sprockets are smaller than the allowable stress values, the chain tension force is less than ultimate tension and transmission error is limited in 1.2%. The noise values can meet the requirements of industrial design, and it is proved that the design and analysis method of the Gemini chain system is scientific and feasible. The design and test system is built from analysis to test of Gemini chain system. This research presented will provide a corresponding theoretical guidance for the design and dynamic characteristics and noise characteristics of chain drive system.

  15. Results from the Gemini NICI Planet-Finding Campaign

    NASA Astrophysics Data System (ADS)

    Biller, Beth A.; Liu, Michael C.; Wahhaj, Zahed; Nielsen, Eric L.; Hayward, Thomas L.; Chun, Mark R.; Close, Laird M.; Ftaclas, Christ; Males, Jared R.; Hartung, Markus; Reid, I. N.; Shkolnik, Evgenya; Skemer, Andrew J.; Tecza, Matthias; Thatte, Niranjan A.; Clarke, Fraser; Toomey, Douglas

    2014-08-01

    From 2008 December to 2012 September, the NICI (Near-Infrared Coronagraphic Imager at the Gemini-South 8.1-m) Planet-Finding Campaign (Liu et al. 2010) obtained deep, high-contrast AO imaging of a carefully selected sample of over 200 young, nearby stars. In the course of the campaign, we discovered four co-moving brown dwarf companions: PZ Tel B (36+/-6 MJup, 16.4+/-1.0 AU), CD-35 2722B (31+/-8 MJup, 67+/-4 AU), HD 1160B (33+12 -9 MJup, 81+/- AU), and HIP 79797Bb (55+20-19MJup, 3 AU from the previously known brown dwarf companion HIP 79797Ba), as well as numerous stellar binaries. Three survey papers have been published to date, covering: 1) high mass stars (Nielsen et al. 2013), 2) debris disk stars (Wahhaj et al. 2013), and 3) stars which are members of nearby young moving groups (Biller et al. 2013). In addition, the Campaign has yielded new orbital constraints for the ~8-10 MJup planet Pic β (Nielsen et al. 2014) and a high precision measurement of the star-disk offset for the well-known disk around HR 4796A (Wahhaj et al. 2014). Here we discuss constraints placed on the distribution of wide giant exoplanets from the NICI Campaign, new substellar companion discoveries, and characterization both of exoplanets and circumstellar disks.

  16. The Gemini Planet Imager Exoplanet Survey (GPIES) Campaign Initial Results

    NASA Astrophysics Data System (ADS)

    Patience, Jennifer; Macintosh, Bruce; Graham, James R.; Barman, Travis; De Rosa, Robert; Konopacky, Quinn; Marley, Mark; Marois, Christian; Nielsen, Eric Ludwig; Pueyo, Laurent; Rajan, Abhijith; Rameau, Julien; Saumon, Didier; Wang, Jason

    2015-12-01

    The Gemini Planet Imager (GPI) is a next-generation coronagraphic integral field unit with the sensitivity and resolution to detect planetary companions with separations of 0”.2 to 1”.0 around a large set of stars. An 890-hour GPI survey of 600 young, nearby stars commenced in late-2014, and approximately 100 stars have been observed thus far. The central aims of the program are: (1) the discovery of a population of giant planets with orbital radii of 5-50 AU comparable to Solar System gas giant orbits, (2) the characterization of the atmospheric properties of young planetary companions, and (3) the exploration of planet-disk interactions. Initial results from GPI exoplanet observations include the discovery of a new planetary companion to a young F-star; the planet spectrum shows a strong signature of methane absorption, indicating a cooler temperature than previously imaged young planets. An overview of the survey scope, current detection limits, and initial results will be presented.

  17. Properties of Ellipticity Correlation with Atmospheric Structure from Gemini South

    SciTech Connect

    Asztalos, S J; Treadway, T; de Vries, W H; Rosenberg, L J; Burke, D; Claver, C; Saha, A; Puxley, P

    2006-12-21

    Cosmic shear holds great promise for a precision independent measurement of {Omega}{sub m}, the mass density of the universe relative to the critical density. The signal is expected to be weak, so a thorough understanding of systematic effects is crucial. An important systematic effect is the atmosphere: shear power introduced by the atmosphere is larger than the expected signal. Algorithms exist to extract the cosmic shear from the atmospheric component, though a measure of their success applied to a range of seeing conditions is lacking. To gain insight into atmospheric shear, Gemini South imaging in conjunction with ground condition and satellite wind data were obtained. We find that under good seeing conditions Point-Spread-Function (PSF) correlations persist well beyond the separation typical of high-latitude stars. Under these conditions, ellipticity residuals based on a simple PSF interpolation can be reduced to within a factor of a few of the shot-noise induced ellipticity floor. We also find that the ellipticity residuals are highly correlated with wind direction. Finally, we correct stellar shapes using a more sophisticated procedure and generate shear statistics from stars. Under all seeing conditions in our data set the residual correlations lie everywhere below the target signal level. For good seeing we find that the systematic error attributable to atmospheric turbulence is comparable in magnitude to the statistical error (shape noise) over angular scales relevant to present lensing surveys.

  18. Properties of Ellipticity Correlation with Atmospheric Structure From Gemini South

    SciTech Connect

    Asztalos, Stephen J.; de Vries, W.H.; Rosenberg, L.J; Treadway, T.; Burke, D.; Claver, C.; Saha, A.; Puxley, P.; /Gemini Observ., La Serena

    2007-01-17

    Cosmic shear holds great promise for a precision independent measurement of {Omega}{sub m}, the mass density of the universe relative to the critical density. The signal is expected to be weak, so a thorough understanding of systematic effects is crucial. An important systematic effect is the atmosphere: shear power introduced by the atmosphere is larger than the expected signal. Algorithms exist to extract the cosmic shear from the atmospheric component, though a measure of their success applied to a range of seeing conditions is lacking. To gain insight into atmospheric shear, Gemini South imaging in conjunction with ground condition and satellite wind data were obtained. We find that under good seeing conditions Point-Spread-Function (PSF) correlations persist well beyond the separation typical of high-latitude stars. Under these conditions, ellipticity residuals based on a simple PSF interpolation can be reduced to within a factor of a few of the shot-noise induced ellipticity floor. We also find that the ellipticity residuals are highly correlated with wind direction. Finally, we correct stellar shapes using a more sophisticated procedure and generate shear statistics from stars. Under all seeing conditions in our data set the residual correlations lie everywhere below the target signal level. For good seeing we find that the systematic error attributable to atmospheric turbulence is comparable in magnitude to the statistical error (shape noise) over angular scales relevant to present lensing surveys.

  19. User interface for the control of the Gemini Telescopes

    NASA Astrophysics Data System (ADS)

    Smith, Steven S.; Gillies, Kim K.

    1997-09-01

    A discussion of the interactive operator user interface developed for the Gemini 8-m Telescopes is presented. Topics include the use of a layered synthesized view of the area of interest on the sky, a data driven approach to the control of the subsystems, and an adaptive view on the health of those subsystems. The synthesized view utilizes information from pre-existing databases; guide, wavefront and scientific detector image data; as well as operating and performance limits. This information is presented to the user in layers, with each layer containing an observer, subsystem or other logically oriented view. The ability to control which layers are presented, as well as which parameters are directly modifiable is vested in both the user and the configuration software. Implementing this above a data driven control interface encourages the use of observing templates. Exhaustive parameter control with parallel realization in the lower level mechanisms results in fast, fine grained and repeatable control. Combining the major control interfaces, each with a different view of the desired behavior, error in behavior, and possible corrections allows the operator to spend more time optimizing observations, rather than setting up equipment. Maximizing time with quality light falling on the science detectors is a primary goal.

  20. Health and Environmental Effects Profile for methyl bromide

    SciTech Connect

    Not Available

    1986-06-01

    The Health and Environmental Effects Profile for methyl bromide was prepared to support listings of hazardous constituents of a wide range of waste streams under Section 3001 of the Resource Conservation and Recovery Act (RCRA) and to provide health-related limits for emergency actions under Section 101 of the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA). Both published literature and information obtained from Agency program office files were evaluated as they pertained to potential human health, aquatic life, and environmental effects. Quantitative estimates are presented provided sufficient data are available. Methyl bromide has been determined to be a systemic toxicant. An Acceptable Daily Intake (ADI), for methyl bromide is 0.0014 mg/kg/day for oral exposure. The Reportable Quantity (RQ) value for methyl bromide is 100.

  1. Methyl bromide as a microbicidal fumigant for tree nuts.

    PubMed Central

    Schade, J E; King, A D

    1977-01-01

    Methyl bromide (MeBr) has broad microbicidal activity, but its use as a disinfectant for food is limited by the resulting bromide residues. Increasing the MeBr concentration, exposure temperature, or exposure period of a treatment tended to increase both the microbicidal efficacy of MeBr and the bromide residues. Its sporicidal activity was less at high than at low relative humidity within the range of 20 to 99%. Both the efficacy and the resulting residues of a MeBr treatment varied inversely with the load of product in a fumigation chamber due to sorption of the fumigant. Fumigation tests with almond kernels inoculated with Escherichia coli or Salmonella typhimurium indicated that MeBr can be used to disinfect whole nut kernels without resulting in excessive bromide residues, although the MeBr level necessary is higher than that normally used for insect control. PMID:406844

  2. 7 CFR 305.6 - Methyl bromide fumigation treatment schedules.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., fumigation with methyl bromide for sapote fruit fly. Regulated citrus fruits originating inside an area quarantined for sapote fruit fly that are to be moved outside the quarantined area may be treated with...

  3. Synthesis and Monolayer Behaviors of Succinic Acid-Type Gemini Surfactants Containing Semifluoroalkyl Groups.

    PubMed

    Kawase, Tokuzo; Nagase, Youhei; Oida, Tatsuo

    2016-01-01

    In this work, novel succinic acid-type gemini surfactants containing semifluoroalkyl groups, dl- and meso-2,3-bis[Rf-(CH2)n]-succinic acids (Rf = C4F9, C6F13, C8F17; n = 2, 9), were successfully synthesized, and the effects of Rf, methylene chain length (n), and stereochemistry on their monolayer behaviors were studied. Critical micelle concentrations (CMC) of dl- and meso-2,3-bis[C4F9(CH2)9]-succinic acids were one order of magnitude smaller than that of the corresponding 1+1 type surfactant, C4F9(CH2)9COOH. From surface pressure-area (π-A) measurements, the lift-off areas of the geminis were found to decrease in the order C4F9 ≥ C6F13 > C8F17, regardless of methylene chain length and stereochemistry. The zero-pressure molecular areas of the geminis were twice those of the corresponding 1+1 type surfactants. Based on Gibbs compression modulus analysis, it was clarified that 2,3-bis[C8F17(CH2)n]-succinic gemini with short methylene chains (n = 2) would form more rigid monolayers than those having long methylene chains (n = 9). Unlike for 2,3-bis(alkyl)-succinic acids, the effects of stereochemistry on the monolayer behavior of semifluoroalkylated geminis were small.

  4. Antibacterial Activity, in Vitro Cytotoxicity, and Cell Cycle Arrest of Gemini Quaternary Ammonium Surfactants.

    PubMed

    Zhang, Shanshan; Ding, Shiping; Yu, Jing; Chen, Xuerui; Lei, Qunfang; Fang, Wenjun

    2015-11-10

    Twelve gemini quaternary ammonium surfactants have been employed to evaluate the antibacterial activity and in vitro cytotoxicity. The antibacterial effects of the gemini surfactants are performed on Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) with minimum inhibitory concentrations (MIC) ranging from 2.8 to 167.7 μM. Scanning electron microscopy (SEM) analysis results show that these surfactants interact with the bacterial cell membrane, disrupt the integrity of the membrane, and consequently kill the bacteria. The data recorded on C6 glioma and HEK293 human kidney cell lines using an MTT assay exhibit low half inhibitory concentrations (IC50). The influences of the gemini surfactants on the cell morphology, the cell migration ability, and the cell cycle are observed through hematoxylin-eosin (HE) staining, cell wound healing assay, and flow cytometric analyses, respectively. Both the values of MIC and IC50 decrease against the growth of the alkyl chain length of the gemini surfactants with the same spacer group. In the case of surfactants 12-s-12, the MICs and IC50s are found to decrease slightly with the spacer chain length changing from 2 to 8 and again to increase at higher spacer length (s = 10-12). All of the gemini surfactants show great antibacterial activity and cytotoxicity, and they might exhibit potential applications in medical fields.

  5. Synthesis and Monolayer Behaviors of Succinic Acid-Type Gemini Surfactants Containing Semifluoroalkyl Groups.

    PubMed

    Kawase, Tokuzo; Nagase, Youhei; Oida, Tatsuo

    2016-01-01

    In this work, novel succinic acid-type gemini surfactants containing semifluoroalkyl groups, dl- and meso-2,3-bis[Rf-(CH2)n]-succinic acids (Rf = C4F9, C6F13, C8F17; n = 2, 9), were successfully synthesized, and the effects of Rf, methylene chain length (n), and stereochemistry on their monolayer behaviors were studied. Critical micelle concentrations (CMC) of dl- and meso-2,3-bis[C4F9(CH2)9]-succinic acids were one order of magnitude smaller than that of the corresponding 1+1 type surfactant, C4F9(CH2)9COOH. From surface pressure-area (π-A) measurements, the lift-off areas of the geminis were found to decrease in the order C4F9 ≥ C6F13 > C8F17, regardless of methylene chain length and stereochemistry. The zero-pressure molecular areas of the geminis were twice those of the corresponding 1+1 type surfactants. Based on Gibbs compression modulus analysis, it was clarified that 2,3-bis[C8F17(CH2)n]-succinic gemini with short methylene chains (n = 2) would form more rigid monolayers than those having long methylene chains (n = 9). Unlike for 2,3-bis(alkyl)-succinic acids, the effects of stereochemistry on the monolayer behavior of semifluoroalkylated geminis were small. PMID:26743669

  6. The oceans: A source or a sink of methyl bromide?

    SciTech Connect

    Pilinis, C.; King, D.B.; Saltzman, E.S.

    1996-04-15

    The global ocean/atmosphere flux of methyl bromide has been estimated from shipboard measurements of the saturation anomaly. When such data are extrapolated globally on the basis of constant saturation anomaly, the ocean is a net sink for methyl bromide [Lobert et al.]. The same data can also be extrapolated on the basis of steady-state production rate of methyl bromide in the water column, allowing regional and seasonal variations in temperature to affect the saturation anomaly. The authors have carried out this type of extrapolation, and they found that the oceans are a strong net source of methyl bromide to the atmosphere. The difference arises mainly due to slow degradation rates in water of higher latitudes. A reduction of the applied production rate by more than 35% is needed in order to switch the ocean from a source to a sink of methyl bromide. These results demonstrate the sensitivity of current estimates of oceanic flux to assumptions about methyl bromide production and destruction in the water column. 19 refs., 2 fig.

  7. Surface and bulk properties of aqueous decyltrimethylammonium bromide-hexadecyltrimethylammonium bromide mixed system.

    PubMed

    Rodríguez, J L; Sierra, M B; Messina, P V; Morini, M A; Schulz, P C; Del Burgo, P; Junquera, E; Rodríguez, A; Aicart, E

    2007-10-15

    The aqueous mixed system decyltrimethylammonium bromide (C(10)TAB)-hexadecyltrimethylammonium bromide (C(16)TAB) was studied by conductivity, ion-selective electrodes, surface tension, and fluorescence spectroscopy techniques. The mixture critical micelle concentration, cmc(*), aggregation number, N( *), and micelle molar conductivity, Lambda(M)(cmc), showed that the system aggregation is strongly nonideal. Both cmc(*) and N( *) results were analyzed with two different procedures: (i) the regular solution theory on mixed micelles or Rubingh's theory, and (ii) by the determination of the partial critical micelle concentration of the amphiphile component i in the presence of a constant concentration of the other amphiphile component, cmc(i)( *). The Rubingh procedure gives micelles richer in C(16)TAB than the overall mixtures, while procedure (ii) gives micelles having the same composition as in the complete surfactant mixture (alpha(C(10)TAB). Mixed micelles are larger than pure surfactant ones, with nonspherical shape. Using a literature model, the cause of the synergistic effect seems to be a reduction of the hydrocarbon/water contact at the micelle surface when mixed micelles form. Conductivity and ion-selective electrodes indicate that highly ionized premicelles form immediately before the cmc(*). The air/solution interface is strongly nonideal and much richer in C(16)TAB than the composition in the bulk. When micelles form there is a strong desorption from the air/solution interface because micelles are energetically favored when compared with the monolayer.

  8. Solution Properties of Dissymmetric Sulfonate-type Anionic Gemini Surfactants.

    PubMed

    Yoshimura, Tomokazu; Akiba, Kazuki

    2016-01-01

    Dissymmetric and symmetric anionic gemini surfactants, N-alkyl-N'-alkyl-N,N'dipropanesulfonylethylenediamine (CmCnSul, where m and n represent alkyl chain lengths of m-n = 4-16, 6-14, 8-12, 10-10, and 12-12), were synthesized by two- or three-step reactions. Their physicochemical properties were characterized by equilibrium surface tension measurements, steady-state fluorescence spectroscopy of pyrene, and dynamic light scattering. The critical micelle concentration (CMC) of the dissymmetric surfactants C4C16Sul, C6C14Sul, and C8C12Sul was slightly lower than that of the symmetric surfactant C10C10Sul. The occupied area per molecule (A) of C8C12Sul was smaller than that of C10C10Sul, indicating that C8C12Sul has a high surface activity. However, the increase in the degree of dissymmetry from C8C12Sul to C6C14Sul and then to C4C16Sul resulted in high surface tension and large A. Based on the surface tension, the standard free energies of micellization (∆G°mic) and adsorption (∆G°ads), the efficiency of surface adsorption (pC20), and the effectiveness of surface adsorption (CMC/C20) were obtained. These parameters suggested that C8C12Sul formed micelles more readily than the other surfactants. The properties determined from the surface tension indicated that C8C12Sul's ability is intermediate between those of C10C10Sul and C12C12Sul. The pyrene fluorescence and dynamic light scattering results revealed that the micelle size depends on the longer of the two alkyl chains in dissymmetric surfactants.

  9. Gemini spectroscopy of the outer disk star cluster BH176

    NASA Astrophysics Data System (ADS)

    Sharina, M. E.; Donzelli, C. J.; Davoust, E.; Shimansky, V. V.; Charbonnel, C.

    2014-10-01

    Context. BH176 is an old metal-rich star cluster. It is spatially and kinematically consistent with belonging to the Monoceros Ring. It is larger in size and more distant from the Galactic plane than typical open clusters, and it does not belong to the Galactic bulge. Aims: Our aim is to determine the origin of this unique object by accurately determining its distance, metallicity, and age. The best way to reach this goal is to combine spectroscopic and photometric methods. Methods: We present medium-resolution observations of red clump and red giant branch stars in BH176 obtained with the Gemini South Multi-Object Spectrograph. We derive radial velocities, metallicities, effective temperatures, and surface gravities of the observed stars and use these parameters to distinguish member stars from field objects. Results: We determine the following parameters for BH176: Vh = 0 ± 15 km s-1, [Fe/H] = -0.1 ± 0.1, age 7 ± 0.5 Gyr, E(V - I) = 0.79 ± 0.03, distance 15.2 ± 0.2 kpc, α-element abundance [α/Fe] ~ 0.25 dex (the mean of [Mg/Fe], and [Ca/Fe]). Conclusions: BH176 is a member of old Galactic open clusters that presumably belong to the thick disk. It may have originated as a massive star cluster after the encounter of the forming thin disk with a high-velocity gas cloud or as a satellite dwarf galaxy. Appendix A is available in electronic form at http://www.aanda.org

  10. Thermodynamic investigation of the binding of dissymmetric pyrenyl-gemini surfactants to DNA.

    PubMed

    Wettig, Shawn D; Deubry, Rubena; Akbar, Javed; Kaur, Tranum; Wang, Haitang; Sheinin, Tatiana; Joseph, Jamie W; Slavcev, Roderick A

    2010-05-14

    Gemini surfactants have demonstrated significant potential for use in constructing non-viral transfection vectors for the delivery of genes into cells to induce protein expression. Previously, two asymmetric gemini surfactants containing pyrenyl groups in one of the alkyl tails of the surfactants were synthesized as fluorescence probes for use in mechanistic studies of the transfection process. Here we present the results of a thermodynamic investigation of the binding interaction(s) between the pyrenyl-modified surfactants and DNA. The thermodynamics of the interactions have been examined using isothermal titration calorimetry, light scattering, zeta potential, and circular dichroism measurements. Distinct differences are observed between the interaction of 12-s-12 vs. the pyrene modified py-s-12 surfactants with DNA; an intercalated binding is found for the py-s-12 surfactants that disrupts the typical interactions observed between DNA and gemini surfactants.

  11. A comparison of Gemini and ERTS imagery obtained over southern Morocco

    NASA Technical Reports Server (NTRS)

    Blodget, H. W.; Anderson, A. T.

    1973-01-01

    A mosaic constructed from three ERTS MSS band 5 images enlarged to 1:500,000 compares favorably with a similar scale geologic map of southern Morocco, and a near-similar scale Gemini 5 photo pair. A comparative plot of lineations and generalized geology on the three formats show that a significantly greater number of probable fractures are visible on the ERTS imagery than on the Gemini photography, and that both orbital formats show several times more lineaments than were previously mapped. A plot of mineral occurrences on the structural overlays indicates that definite structure-mineralization relationships exist; this finding is used to define underdeveloped areas which are prospective for mineralization. More detailed mapping is possible using MSS imagery than on Gemini 5 photographs, and in addition, the ERTS format is not restricted to limited coverage.

  12. A new look for Gemini: rapid-cured composites for an exchangeable top-end

    NASA Astrophysics Data System (ADS)

    Miziarski, Stan; McGrath, Andrew; Milby, N.; Brosius, D. E.; von Bertouch, M. J.

    2006-06-01

    The Gemini-sponsored WFMOS Feasibility Study investigated a wide-field, prime focus installation for the Gemini telescopes. As constructed, the Gemini design allows for multiple, interchangeable telescope top-ends, although this capability has never been implemented. Constrained by a particularly challenging top-end mass budget, we proposed a new top end specific to WFMOS, employing a carbon fiber reinforced plastic structure. An innovative, out-of-autoclave manufacturing process using balanced pressure and liquid heating and cooling enables high-specification, large CFRP structures to be constructed suitable for incorporation as fundamental parts of telescope structures. Advantages include low weight, enhanced overall telescope stiffness, and cost-effective construction with on-site final assembly. We describe the manufacturing process and the proposed top-end structure, as well as highlighting the advantages of this type of structure and material for large and extremely large telescopes in general.

  13. Structural and transfection properties of amine-substituted gemini surfactant-based nanoparticles

    SciTech Connect

    Wettig,S.; Badea, I.; Donkuru, M.; Verrall, R.; Foldvari, M.

    2007-01-01

    Increases in DNA transfection efficiencies for non-viral vectors can be achieved through rational design of novel cationic building blocks. Based on previous results examining DNA condensation by polyamines, novel gemini surfactants have been designed that incorporate aza or imino substituents within the spacer group in order to increase interactions with DNA and potentially improve their DNA transfection ability. Transfection efficiencies and cell toxicity of gemini nanoparticles constructed from plasmid DNA, gemini surfactant, and a neutral lipid were measured in COS7 cells using a luciferase assay. Structural properties of nanoparticles were examined by using circular dichroism, particle size, zeta potential, and small-angle X-ray scattering (SAXS) measurements. The incorporation of aza and imino substituents within the spacer group was observed to enhance the transfection ability of gemini surfactants. Incorporation of an imino group in the structure of the 1,9-bis(dodecyl)-1,1,9,9-tetramethyl-5-imino-1,9-nonanediammonium dibromide surfactant (12-7NH-12) resulted in a statistically significant (p < 0.01) 9-fold increase in transfection compared to an unsubstituted gemini surfactant and a 3-fold increase compared to the corresponding aza-substituted compound. A pH-dependent transition in size and zeta potential was observed to occur at pH 5.5 for complexes formed from the 12-7NH-12 compound. SAXS results show weakly ordered structures and the presence of multiple phases. The incorporation of a pH-active imino group within the spacer of the gemini surfactant results in a significant increase in transfection efficiency that can be related to both pH-induced changes in nanoparticle structure and the formation of multiple phases that more readily allow for membrane fusion that may facilitate DNA release.

  14. Dielectric Analysis for the Spherical and Rodlike Micelle Aggregates Formed from a Gemini Surfactant: Driving Forces of Micellization and Stability of Micelles.

    PubMed

    Wang, Shanshan; Zhao, Kongshuang

    2016-08-01

    The self-aggregation behavior of Gemini surfactant 12-2-12 (ethanediyl-1,2-bis(dimethyldodecylammonium bromide)) in water was investigated by dielectric relaxation spectroscopy (DRS) over a frequency range from 40 Hz to 110 MHz. Dielectric determination shows that well-defined spherical micelles formed when the concentration of the surfactant was above a critical micelle concentration CMC1 of 3 mM and rodlike micelles formed above CMC2, 16 mM. The formation mechanism of the spherical micelles and their transition mechanism to clubbed micelles were proposed by calculating the degree of counterion binding of the micelles. The interactions between the head groups and the hydrophobic chains of the surfactant led to the formation of the micelles, whereas the transition is mainly attributed to the interaction among the hydrophobic chains. By analyzing the dielectric relaxation observed at about 10(7) Hz based on the interface polarization theory, the permittivity and conductivity of micelle aggregates (spherical and clubbed) and volume fraction of micelles were calculated theoretically as well as the electrical properties of the solution medium. Furthermore, we also calculated the electrokinetic parameters of the micelle particle surface, surface conductivity, surface charge density, and zeta potential, using the relaxation parameters and phase parameters. On the basis of these results, the balance of forces controlling morphological transitions, interfacial electrokinetic properties, and the stability of the micelle aggregates was discussed. PMID:27396495

  15. Conformational changes of DNA in the presence of 12-s-12 gemini surfactants (s=2 and 10). Role of the spacer's length in the interaction surfactant-polynucleotide.

    PubMed

    García, J P; Marrón, E; Martín, V I; Moyá, M L; Lopez-Cornejo, P

    2014-06-01

    A multifaceted study on the interaction of calf-thymus DNA with two different cationic gemini surfactants alkanediyl-α-ω-bis(dodecyldimethyl-amonium)bromide, 12-s-12,2Br(-) (with s=2, G2, and 10, G10) was carried out. The measurements were done at different molar ratios X=[surfactant]/[DNA]. Results show two different conformational changes in DNA: a first compaction of the polynucleotide corresponding to a partial conformational (not total) change of DNA from an extended coil state to a globular state that happens at the lower molar ratio X. A second change corresponds to a breaking of the partial condensation, that is, the transition from the compacted state to a new more extended conformation (for the higher X values) different to the initial extension. According to circular dichroism spectra and dynamic light scattering measurements, this new state of DNA seems to be similar to a ψ-phase. Measurements confirm that interactions involved in the compaction are different to those previously obtained for the analog surfactant CTAB. X values at which the conformational changes happen depend on the length of the spacer in the surfactant along with the charge of the polar heads.

  16. Bromide therapy in refractory canine idiopathic epilepsy.

    PubMed

    Podell, M; Fenner, W R

    1993-01-01

    On a retrospective basis, the response to adding chronic oral bromide (BR) to phenobarbital (PB) administration in 23 refractory canine idiopathic epileptics between 1986 and 1991 was studied. The mean age for an observed first seizure was 24 months (range 7 to 72) for all dogs. Thirteen (57%) dogs were males with no breed predisposition observed. All dogs were diagnosed as having idiopathic epilepsy based on normal metabolic and neurologic diagnostic evaluations. Dogs were evaluated before BR therapy for a mean time of 22 months (range 5 to 75 months). Seventeen dogs (74%) received multiple antiepileptic drugs (AEDs) before BR therapy. All animals were maintained on PB at least 4 months before the onset of BR therapy, with a mean trough serum concentration of 37.8 mcg/mL and no improvement in seizure severity or recurrence. Twelve dogs presented with generalized isolated seizures and 11 with generalized cluster seizures (two or more seizures within 24 hours) as their first seizure. The effects of BR therapy were evaluated for a mean time of 15 months (range 4 to 33), with 17 dogs (74%) followed for 12 or more months. The mean BR serum concentration for the 0 to 4 months time period was 117 mg/dL compared with 161 mg/dL for the greater than 4 months period. Overall, response to BR therapy was associated with a reduction in the total number of seizures in 83% of the dogs when compared with their respective pre-BR period. For those followed for 1 year after BR, there was a 53% reduction in the number of seizures compared with the previous 12 months. Furthermore, owners reported a decrease in seizure intensity (65% of dogs) and change to a less severe seizure type (22% of dogs) in those dogs that continued to have seizures. Seizure-free status was obtained in 26% of the dogs with protection continuing up to 31 months in one dog. No correlations could be determined between response to BR and either age of onset of the first seizure or interval from the first AED

  17. Disposition of ( UC)methyl bromide in rats after inhalation

    SciTech Connect

    Bond, J.A.; Dutcher, J.S.; Medinsky, M.A.; Henderson, R.F.; Birnbaum, L.S.

    1985-01-01

    The purpose of this investigation was to determine the disposition and metabolism of ( UC)methyl bromide in rats after inhalation. Male Fischer-344 rats were exposed nose only to a vapor concentration of 337 nmol ( UC)methyl bromide/liter air (9.0 ppm, 25C, 620 torr) for 6 hr. Urine, feces, expired air, and tissues were collected for up to 65 hr after exposure. Elimination of UC as UCO2 was the major route of excretion with about 47% (3900 nmol/rat) of the total ( UC)methyl bromide absorbed excreted by this route. CO2 excretion exhibited a biphasic elimination pattern with 85% of the UCO2 being excreted with a half-time of 3.9 +/- 0.1 hr (anti x +/- SE) and 15% excreted with a half-time of 11.4 +/- 0.2 hr. Half-times for elimination of UC in urine and feces were 9.6 +/- 0.1 and 16.1 +/- 0.1 hr, respectively. By 65 hr after exposure, about 75% of the initial radioactivity had been excreted with 25% remaining in the body. Radioactivity was widely distributed in tissues immediately following exposure with lung (250 nmol equivalents/g), adrenal (240 nmol equivalents/g), and nasal turbinates (110 nmol equivalents/g) containing the highest concentrations of UC. Radioactivity in livers immediately after exposure accounted for about 17% of the absorbed methyl bromide. Radioactivity in all other tissues examined accounted for about 10% of the absorbed methyl bromide. Elimination half-times of UC from tissues were on the order of 1.5 to 8 hr. In all tissues examined, over 90% of the UC in the tissues was methyl bromide metabolities. The data from this study indicate that after inhalation methyl bromide is rapidly metabolized in tissues and readily excreted. 22 references, 4 figures, 4 tables.

  18. Modern Gemini-Approach to Technology Development for Human Space Exploration

    NASA Technical Reports Server (NTRS)

    White, Harold

    2010-01-01

    In NASA's plan to put men on the moon, there were three sequential programs: Mercury, Gemini, and Apollo. The Gemini program was used to develop and integrate the technologies that would be necessary for the Apollo program to successfully put men on the moon. We would like to present an analogous modern approach that leverages legacy ISS hardware designs, and integrates developing new technologies into a flexible architecture This new architecture is scalable, sustainable, and can be used to establish human exploration infrastructure beyond low earth orbit and into deep space.

  19. Deep-depletion Hamamatsu CCDs for the Gemini multi-object spectrograph

    NASA Astrophysics Data System (ADS)

    Hardy, Tim; Hanna, Kevin; Szeto, Kei; Burley, Greg

    2012-07-01

    The instrumentation group of the Herzberg Institute of Astrophysics was commissioned by the Gemini Observatory to develop a new focal plane assembly for the Gemini Multi-Object Spectrograph with an array of three deep-depletion Hamamatsu CCDs. The main objective of the upgrade is to improve the sensitivity of the instrument in the red and nearinfrared wavelengths, with the additional benefits of reduced fringing, faster readout, and better performance in the "nod and shuffle" mode. We describe what we learned about these relatively new CCDs, including several problems encountered during testing, and report on the performance of the system.

  20. An ultra short pulse reconstruction software applied to the GEMINI high power laser system

    NASA Astrophysics Data System (ADS)

    Galletti, Mario; Galimberti, Marco; Hooker, Chris; Chekhlov, Oleg; Tang, Yunxin; Bisesto, Fabrizio Giuseppe; Curcio, Alessandro; Anania, Maria Pia; Giulietti, Danilo

    2016-09-01

    The GRENOUILLE traces of Gemini pulses (15 J, 30 fs, PW, shot per 20 s) were acquired in the Gemini Target Area PetaWatt at the Central Laser Facility (CLF), Rutherford Appleton Laboratory (RAL). A comparison between the characterizations of the laser pulse parameters made using two different types of algorithms: Video Frog and GRenouille/FrOG (GROG), was made. The temporal and spectral parameters came out to be in great agreement for the two kinds of algorithms. In this experimental campaign it has been showed how GROG, the developed algorithm, works as well as VideoFrog algorithm with the PetaWatt pulse class.

  1. UV photodissociation of methyl bromide and methyl bromide cation studied by velocity map imaging

    SciTech Connect

    Blanchet, Valerie; Samartzis, Peter C.; Wodtke, Alec M.

    2009-01-21

    We employ the velocity map imaging technique to measure kinetic energy and angular distributions of state selected CH{sub 3} (v{sub 2}=0,1,2,3) and Br ({sup 2}P{sub 3/2}, {sup 2}P{sub 1/2}) photofragments produced by methyl bromide photolysis at 215.9 nm. These results show unambiguously that the Br and Br* forming channels result in different vibrational excitations of the umbrella mode of the methyl fragment. Low energy structured features appear on the images, which arise from CH{sub 3}Br{sup +} photodissociation near 330 nm. The excess energy of the probe laser photon is channeled into CH{sub 3}{sup +} vibrational excitation, most probably in the {nu}{sub 4} degenerate bend.

  2. Zinc Bromide Combustion: Implications for the Consolidated Incinerator Facility

    SciTech Connect

    Oji, L.N.

    1998-12-16

    In the nuclear industry, zinc bromide (ZnBr2) is used for radiation shielding. At Savannah River Site (SRS) zinc bromide solution, in appropriate configurations and housings, was used mainly for shielding in viewing windows in nuclear reactor and separation areas. Waste stream feeds that will be incinerated at the CIF will occasionally include zinc bromide solution/gel matrices.The CIF air pollution systems control uses a water-quench and steam atomizer scrubber that collects salts, ash and trace metals in the liquid phase. Water is re-circulated in the quench unit until a predetermined amount of suspended solids or dissolved salts are present. After reaching the threshold limit, "dirty liquid", also called "blowdown", is pumped to a storage tank in preparation for treatment and disposal. The air pollution control system is coupled to a HEPA pre-filter/filter unit, which removes particulate matter from the flue gas stream (1).The objective of this report is to review existing literature data on the stability of zinc bromide (ZnBr2) at CIF operating temperatures (>870 degrees C (1600 degrees F) and determine what the combustion products are in the presence of excess air. The partitioning of the combustion products among the quencher/scrubber solution, bottom ash and stack will also be evaluated. In this report, side reactions between zinc bromide and its combustion products with fuel oil were not taken into consideration.

  3. Electrophysiological study of intravenous pinaverium bromide in cardiology.

    PubMed

    Guerot, C; Khemache, A; Sebbah, J; Noel, B

    1988-01-01

    Pinaverium bromide is a musculotropic spasmolytic agent which acts by inhibiting transmembrane calcium movements, an effect similar to that of verapamil. Because of this, an investigation was carried out to see if it had any electrophysiological effects in patients with various cardiac disorders. In an open study, 10 patients received 2 mg pinaverium bromide intravenously. In a double-blind study, 10 patients received 4 mg pinaverium bromide intravenously and 10 patients placebo. Patients included those with either normal or pathological basal conduction, such as bundle-branch block and 1st degree atrioventricular block. Measurements were made of electrophysiological parameters before and 10 minutes after injection. The results showed that neither of the two doses of pinaverium bromide had any effect on atrial excitability, sino-atrial conduction, node and trunk atrioventricular conduction or on intraventricular conduction. No significant difference was seen in comparison with placebo. Pinaverium bromide had no anti-arrhythmic properties in these studies. Local, cardiac and general clinical tolerability was good in all patients. PMID:3219882

  4. Does bromide cause conversion of epilepsy to psychosis?

    PubMed

    Lund, M

    1997-04-01

    The aim of this study is to find out whether bromide was able to cause conversion of epilepsy to psychosis i.e., so-called paradoxical normalization such as has been seen in treatment with modern antiepileptic drugs. Spontaneous conversion has been known for three hundred years. Locock introduced bromide in the treatment of epilepsy in 1857. Belgrave wrote in 1868 on its effect on epileptic attacks and concommitant insanity. In 1868 Holm observed reduction of the frequency of seizures at the same time as psychotic symptoms or just dysphoria. In 1875 Voisin described a dose-dependent intoxication with psychosis and/or neurological signs. Stark in 1875 and Bannister in 1881 were the first to clearly describe the antagonism between epileptic seizures and psychotic symptoms, an antagonism or conversion described by many authors, both in cases with high and low dosage, and with and without intoxication. Thus, the title of this paper should be answered in the affirmative. Bromide has been used as a sedative and has rarely caused intoxication. Thus the presence of epilepsy is not a condition for the development of bromide intoxication. A case with epilepsy and fatal massive bromide intoxication is reported. It is discussed whether the pathological findings give support to Wolf's hypothesis of latent epileptic activity in subcortical pathways during "normalization".

  5. Effect of Bromide-Hypochlorite Bactericides on Microorganisms1

    PubMed Central

    Shere, Lewis; Kelley, Maurice J.; Richardson, J. Harold

    1962-01-01

    A new principle in compounding stable, granular bactericidal products led to unique combinations of a water-soluble inorganic bromide salt with a hypochlorite-type disinfectant of either inorganic or organic type. Microbiological results are shown for an inorganic bactericide composed of chlorinated trisodium phosphate containing 3.1% “available chlorine” and 2% potassium bromide, and for an organic bactericide formulated from sodium dichloroisocyanurate so as to contain 13.4% “available chlorine” and 8% potassium bromide. Comparison of these products with their nonbromide counterparts are reported for Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Streptococcus lactis, Aerobacter aerogenes, and Proteus vulgaris. Test methods employed were the Chambers test, the A.O.A.C. Germicidal and Detergent Sanitizer-Official test, and the Available Chlorine Germicidal Equivalent Concentration test. The minimal killing concentrations for the bromide-hypochlorite bactericides against this variety of organisms were reduced by a factor 2 to 24 times those required for similar hypochlorite-type disinfectants not containing the bromide. PMID:13977149

  6. IR, Raman and SERS spectra of propantheline bromide.

    PubMed

    Baraldi, C; Freguglia, G; Tinti, A; Sparta, M; Alexandrova, A N; Gamberini, M C

    2013-02-15

    The two known propantheline bromide polymorphs (form I and form II) were studied and characterized by a multianalytical approach. In the present work, the identification of propantheline bromide polymorphic forms through vibrational IR spectroscopies are presented and for the first time Raman microscopy and hot stage Raman microscopy (HSRM) studies are reported. Finally, quantum mechanical calculations were performed. For assisting the assignment of the experimental picks, the two IR spectra of the most and least stable representatives of a set of 56 conformers are calculated and studied. DSC thermograms data, are also reported. The surface enhanced Raman scattering (SERS) spectrum was also recorded in a silver colloid; it could be inferred that propantheline bromide is adsorbed on silver colloid through the oxygen atom with the molecular plane perpendicular to the metal surface.

  7. Intensification of sonochemical degradation of malachite green by bromide ions.

    PubMed

    Moumeni, Ouarda; Hamdaoui, Oualid

    2012-05-01

    Sonochemical oxidation has been investigated as a viable advanced oxidation process (AOP) for the destruction of various pollutants in water. Ultrasonic irradiation generates ()OH radicals that can recombine, react with other gaseous species present in the cavity, or diffuse out of the bubble into the bulk liquid medium where they are able to react with solute molecules. The extent of degradation of an organic dye such as malachite green (MG) is limited by the quantity of hydroxyl radicals diffused from cavitation bubbles. In this work, the effect of bromide ions on sonolytic degradation of MG was investigated. The obtained results clearly demonstrated the considerable enhancement of sonochemical destruction of MG in the presence of bromide. No significant differences were observed in the presence of chloride and sulfate, excluding the salting-out effect. Positive effect of bromide ions, which increases with increasing bromide level and decreasing MG concentration, is due to the generation of dibromine radical anion (Br(2)(-)) formed by reaction of Br(-) with ()OH radicals followed by rapid complexation with another anion. The generated Br(2)(-) radicals, reactive but less than ()OH, are likely able to migrate far from the cavitation bubbles towards the solution bulk and are suitable for degradation of an organic dye such as MG. Additionally, Br(2)(-) radicals undergo radical-radical recombination at a lesser extent than hydroxyl radicals and would be more available than ()OH for substrate degradation, both at the bubble surface and in the solution bulk. This effect compensates for the lower reactivity of Br(2)(-) compared to ()OH toward organic substrate. Addition of bromide to natural and sea waters induces a slight positive effect on MG degradation. In the absence of bromide, ultrasonic treatment for the removal of MG was promoted in complex matrices such as natural and sea waters.

  8. Methyl bromide emissions from a covered field: II. Volatilization

    SciTech Connect

    Yates, S.R.; Gan, J.; Ernst, F.F.

    1996-01-01

    An experiment to investigate the environmental fate and transport of methyl bromide in agricultural fields is described. The methyl bromide volatilization rate was determined as a function of time for conditions where methyl bromide was applied at a rate of 843 kg in a 3.5-ha (i.e., 240 kg/ha) field covered with plastic at a depth of 25 cm. Three methods were used to estimate the methyl bromide volatilization rate, including: the aerodynamic, theoretical profile shape and integrated horizontal flux methods. The highest methyl bromide volatilization rates were at the beginning of the experiment. Within the first 24 h, approximately 36% of the applied methyl bromide mass was lost. Diurnally, the largest volatilization rates occurred during the day when temperatures were high and the atmosphere was unstable. Cooler temperatures, light winds, and neutral to stable atmospheric conditions were present at night, reducing the flux. The total emission calculated using these methods was found to be approximately 64% ({+-} 10%) of the applied mass. A mass balance was calculated using each flux estimation technique and several methods for analyzing the data. The average mass recovery using all the flux methods was 867 kg ({+-}83 kg), which was 102.8% ({+-}9.8%) of the applied (i.e., 843 kg). The range in the mass balance percent (i.e., percent of applied mass that is measured) is from 88 to 112%. The averaged mass balance percent for the aerodynamic method, which involved using the measured data directly, was approximately 100.8%. The total emission calculated using the aerodynamic method was found to be approximately 62% ({+-}11%) of the applied mass. 29 refs., 7 figs., 1 tab.

  9. Photochemistry of alkyl bromides trapped in water ice films

    NASA Astrophysics Data System (ADS)

    Schrems, O.; Okaikwei, B.; Bluszcz, Th.

    2012-04-01

    Photochemical reactions of atmospheric trace gases taking place at the surface of atmospheric ice particles and in bulk ice are important in stratospheric and tropospheric chemistry but also in polar and alpine snowpack chemistry. Consequently, the understanding of the uptake und incorporation of atmospheric trace gases in water ice as well as their interactions with water molecules is very important for the understanding of processes which occur in ice particles and at the air/ice interface. Reactive atmospheric trace gases trapped in ice are subject of photochemical reactions when irradiated with solar UV radiation. Among such compounds bromine species are highly interesting due to their potential of depleting ozone both in the stratosphere and troposphere. Organic bromine gases can carry bromine to the stratosphere. Methyl bromide (CH3Br) is the largest bromine carrier to the stratosphere. It has both natural and anthropogenic sources. In this contribution we will present the results of our laboratory studies of alkyl bromides (methyl, bromide (CH3Br), dimethyl bromide (CH2Br2), n-propyl bromide (C3H7Br), 1,2-dibromoethane C2H4Br2)), trapped in water ice. We have simulated the UV photochemistry of these brominated alkanes isolated in ice films kept at 16 K and for comparison in solid argon matrices. The photoproducts formed in the ice have been identified by means of FTIR spectroscopy. Reflection absorption infrared spectroscopy (RAIRS) is especially useful to study nascent ice surfaces, kinetics of adsorption/decomposition, and heterogeneous catalysis. Among the observed photoproducts we could identify carbon monoxide and carbon dioxide for each alkyl bromide studied. The photoproduct HBr is dissociated in the bulk ice. Based on the experimental observations possible reaction mechanisms will be discussed.

  10. Gulf Coast area from Texas to Louisiana seen from the Gemini 12 spacecraft

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Gulf Coast area from Matagorda Bay, Texas to Vermillion Bay, Louisiana, looking east, as seen from the Gemini 12 spacecraft during its 44th revolution of the earth. Galveston Bay is in center of picture. Houston and its environs are clearly visible. Note network of freeways and superhighways. Large lake near left center of picture is the Sam Rayburn Reservoir.

  11. U.S. Gulf Coast as seen from Gemini 11 spacecraft

    NASA Technical Reports Server (NTRS)

    1966-01-01

    U.S. Gulf coast area from Aransas Bay, Texas to Mobile Bay, Alabama, as seen from the Gemini 11 spacecraft during its 29th revolution of the earth. The Galveston Bay and Houston area is in center of photograph. Further eastward along the coast can be seen the Mississippi River delta and New Orleans area.

  12. Crewmen of the U.S.S. Wasp watching recovery of Gemini 7 spacecraft

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Crewmen of the aircraft carrier U.S.S. Wasp gather on deck to watch the recovery of the Gemini 7 spacecraft and astronauts. Note the signs hanging from the railings which say 'Seasons Greetings from WASP' and 'Spirit of 76'.

  13. Crewmen of the U.S.S. Wasp watching recovery of Gemini 6 spacecraft

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Crewmen of the aircraft carrier U.S.S. Wasp gather on deck to watch the recovery of the Gemini 6 spacecraft and astronauts. Note the signs hanging from the railings which say 'Seasons Greetings from WASP' and 'Spirit of 76'.

  14. Gemini 12 crew cut cake aboard U.S.S. Wasp

    NASA Technical Reports Server (NTRS)

    1966-01-01

    A happy Gemini 12 prime crew slice a cake made aboard the aircraft carrier, U.S.S. Wasp. Astronauts James A. Lovell Jr. (left), command pilot, and Edwin E. Aldrin Jr., pilot, had just been picked up from the splashdown area by helicopter.

  15. Gemini 9-A astronauts welcomed aboard U.S.S. Wasp

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Astronauts Thomas Stafford and Eugene Cernan (right) receive a warm welcome as they arrive aboard the prime recovery ship, the aircraft carrier U.S.S. Wasp. John C. Stonesifer, with the Manned Spacecraft Center's Landing and Recovery Division, stands next to microphone at left. The Gemini 9 spacecraft can be seen in the right background of the view.

  16. Some results of biomedical studies carried out in the Gemini and Apollo programs

    NASA Technical Reports Server (NTRS)

    Kopanev, V. I.; Yuganov, Y. M.

    1975-01-01

    Biomedical changes in Gemini and Apollo astronauts indicate physiological shifts in the majority of organs and systems of the body during space flight. Weightlessness conditions affected body weight, blood circulation, hematological indices, metabolisms, etc. Prophylactic measures to minimize the various physiological and psychological effects constitute activity and rest cycles, supplementary potassium addition to space food, artificial gravity, etc.

  17. Cationic gemini surfactants with cleavable spacer: chemical hydrolysis, biodegradation, and toxicity.

    PubMed

    Tehrani-Bagha, A R; Holmberg, K; van Ginkel, C G; Kean, M

    2015-07-01

    The paper describes synthesis and characterization of a new type of cationic gemini surfactant, which has dodecyl tails and a spacer that contains an ester bond. The nomenclature used to describe the structure is 12Q2OCO1Q12, with Q being a quaternary ammonium group and the numbers indicating the number of methylene or methyl groups. Due to the close proximity to the two quaternary ammonium groups, the ester bond is very stable on the acid side and very labile already at slightly alkaline conditions. The hydrolysis products are two single chain surfactants (i.e. 12Q2OH and 12Q1COOH) which are less surface active than the intact gemini surfactant. 12Q2OCO1Q12 was found to be readily biodegradable, i.e. it gave more than 60% biodegradation after 28 days. This is interesting because similar gemini surfactants but with ester bonds in the tails instead of the spacer, have previously been found not to be readily biodegradable. The gemini surfactant was found to be toxic to aquatic organisms (ErC50 value of 0.27 mg/l), although less toxic than the two hydrolysis products.

  18. Gemini 11 Commander Conrad and Pilot Gordon at post flight press conference

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Gemini 11 Commander Charles Conrad, Jr (left) and Pilot Richard F. Gordon, Jr describe mission activities during their post flight press conference at JSC. Gordon at the microphone talks about the extravehicular activity (EVA) photo projected behind the two crewmembers. During the EVA Gordon attached a tether to the Agena and retrieved a nuclear emulsion experiment package.

  19. Performance of the Gemini Planet Imager’s adaptive optics system

    DOE PAGES

    Poyneer, Lisa A.; Palmer, David W.; Macintosh, Bruce; Savransky, Dmitry; Sadakuni, Naru; Thomas, Sandrine; Véran, Jean-Pierre; Follette, Katherine B.; Greenbaum, Alexandra Z.; Mark Ammons, S.; et al

    2016-01-07

    The Gemini Planet Imager’s adaptive optics (AO) subsystem was designed specifically to facilitate high-contrast imaging. We give a definitive description of the system’s algorithms and technologies as built. Ultimately, the error budget indicates that for all targets and atmospheric conditions AO bandwidth error is the largest term.

  20. Gemini 4 prime crew with Official medical nurse for Astronaut crew members

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Gemini 4 prime crew, Astronauts Edward H. White II, (left), and James A. McDivitt (right) are shown with Lt. Dolores (Dee) O'Hare, US Air Force, Center Medical Office, Flight Medicine Branch, Manned Spaceflight Center (MSC). Lieutenant O'Hare has served during several space flights as Official medical nurse for the astronaut crew members on the missions.

  1. Biodegradability and aquatic toxicity of quaternary ammonium-based gemini surfactants: Effect of the spacer on their ecological properties.

    PubMed

    Garcia, M Teresa; Kaczerewska, Olga; Ribosa, Isabel; Brycki, Bogumił; Materna, Paulina; Drgas, Małgorzata

    2016-07-01

    Aerobic biodegradability and aquatic toxicity of five types of quaternary ammonium-based gemini surfactants have been examined. The effect of the spacer structure and the head group polarity on the ecological properties of a series of dimeric dodecyl ammonium surfactants has been investigated. Standard tests for ready biodegradability assessment (OECD 310) were conducted for C12 alkyl chain gemini surfactants containing oxygen, nitrogen or a benzene ring in the spacer linkage and/or a hydroxyethyl group attached to the nitrogen atom of the head groups. According to the results obtained, the gemini surfactants examined cannot be considered as readily biodegradable compounds. The negligible biotransformation of the gemini surfactants under the standard biodegradation test conditions was found to be due to their toxic effects on the microbial population responsible for aerobic biodegradation. Aquatic toxicity of gemini surfactants was evaluated against Daphnia magna. The acute toxicity values to Daphnia magna, IC50 at 48 h exposure, ranged from 0.6 to 1 mg/L. On the basis of these values, the gemini surfactants tested should be classified as toxic or very toxic to the aquatic environment. However, the dimeric quaternary ammonium-based surfactants examined result to be less toxic than their corresponding monomeric analogs. Nevertheless the aquatic toxicity of these gemini surfactants can be reduced by increasing the molecule hydrophilicity by adding a heteroatom to the spacer or a hydroxyethyl group to the polar head groups. PMID:27045632

  2. Investigation of possible interaction between pinaverium bromide and digoxin.

    PubMed

    Weitzel, O; Seidel, G; Engelbert, S; Berksoy, M; Eberhardt, G; Bode, R

    1983-01-01

    A single-blind study was carried out in 25 patients, who were receiving maintenance therapy for congestive heart failure with digoxin, to investigate the effect on steady-state plasma digoxin levels of concomitant administration of the spasmolytic, pinaverium bromide (50 mg 3-times daily). Patients received pinaverium bromide for 12 days followed by placebo for a further 7 days. Assessment of the results in 21 patients showed no evidence of any statistically significant variations in plasma digoxin levels during either treatment period or in the clinical observations which might indicate drug interaction. PMID:6653138

  3. Action of pinaverium bromide on calmodulin-regulated functions.

    PubMed

    Wuytack, F; De Schutter, G; Casteels, R

    1985-08-01

    Pinaverium bromide at concentrations below 10(-5) M did not inhibit calmodulin-dependent enzymes such as phosphodiesterase and the Ca transport ATPase of the plasma membrane. At higher concentrations the compound interacted with the stimulation of those enzymes by calmodulin and also inhibited the calmodulin-independent activity. A similar inhibitory action was observed for the NaK ATPase. It is concluded that the inhibitory action of pinaverium bromide on smooth muscle concentration at concentrations below 10(-5) M was due to its interaction with the voltage-dependent Ca channels and not to its interference with the calmodulin-dependent activation of the contractile proteins. PMID:2995077

  4. Adsorption Isotherm studies of Methyl Bromide adsorbed on Magnesium Oxide

    NASA Astrophysics Data System (ADS)

    Burns, Teresa; Sprung, Michael

    2005-03-01

    Understanding the interaction of polar molecules with ionic surfaces is technologically very important. Using high precision, volumetric adsorption isotherms the layering properties of methyl bromide on the MgO(100) surface were examined between 164 K and 179 K. Methyl bromide (Triple point = 179.49K) is found to exhibit two layering transitions within this temperature interval. Thermodynamic quantities derived from this study including the layering transition temperatures, the 2D compressibility, layer enthalpy and entropy of adsorption, and the isosteric enthalpy of adsorption will be presented. Comparisons with the adsorption properties of methyl chloride and methyl iodide will also be included.

  5. Versatile Route to Arylated Fluoroalkyl Bromide Building Blocks.

    PubMed

    Kaplan, Peter T; Vicic, David A

    2016-02-19

    New difunctionalized and fluoroalkylated silyl reagents have been prepared that react with silver and copper salts to afford active catalysts that can be used to synthesize arylated fluoroalkyl bromide building blocks. It has been shown that the [(phen)Ag(CF2)nBr] intermediates are capable of transferring both the phenanthroline ligand and the fluoroalkyl bromide chain to copper iodide, eliminating the need for a preligated copper salt precursor. The methodology is compatible with various chain lengths of the fluoroalkyl halide functionality. PMID:26820388

  6. Theoretical model to investigate the alkyl chain and anion dependent interactions of gemini surfactant with bovine serum albumin.

    PubMed

    Vishvakarma, Vijay K; Kumari, Kamlesh; Patel, Rajan; Dixit, V S; Singh, Prashant; Mehrotra, Gopal K; Chandra, Ramesh; Chakrawarty, Anand Kumar

    2015-05-15

    Surfactants are used to prevent the irreversible aggregation of partially refolded proteins and they also assist in protein refolding. We have reported the design and screening of gemini surfactant to stabilize bovine serum albumin (BSA) with the help of computational tool (iGEMDOCK). A series of gemini surfactant has been designed based on bis-N-alkyl nicotinate dianion via varying the alkyl group and anion. On changing the alkyl group and anion of the surfactant, the value of Log P changes means polarity of surfactant can be tuned. Further, the virtual screening of the gemini surfactant has been carried out based on generic evolutionary method. Herein, thermodynamic data was studied to determine the potential of gemini surfactant as BSA stabilizer. Computational tools help to find out the efficient gemini surfactant to stabilize the BSA rather than to use the surfactant randomly and directionless for the stabilization. It can be confirmed through the experimental techniques. Previously, researcher synthesized one of the designed and used gemini surfactant to stabilize the BSA and their interactions were confirmed through various techniques and computational docking. But herein, the authors find the most competent gemini surfactant to stabilize BSA using computational tools on the basis of energy score. Different from the single chain surfactant, the gemini surfactants exhibit much stronger electrostatic and hydrophobic interactions with the protein and are thus effective at much lower concentrations. Based on the present study, it is expected that gemini surfactants may prove useful in the protein stabilization operations and may thus be effectively employed to circumvent the problem of misfolding and aggregation.

  7. Correlation of the melting points of potential ionic liquids (imidazolium bromides and benzimidazolium bromides) using the CODESSA program.

    PubMed

    Katritzky, Alan R; Jain, Ritu; Lomaka, Andre; Petrukhin, Ruslan; Karelson, Mati; Visser, Ann E; Rogers, Robin D

    2002-01-01

    The melting points of several imidazolium-based ionic liquids or ionic liquid analogues were correlated using the CODESSA program in order to develop predictive tools for determination of suitable ionic liquid salts. The data set consisted of melting point data (degrees C) for 104 substituted imidazolium bromides divided on the basis of the N-substituents into three subsets: A-57 compounds, B-29 compounds, and C-18 compounds. The 45 benzimidazolium bromides form set D. Five-parameter correlations were obtained for (i) set A with R2 = 0.7442, (ii) set B with R2 = 0.7517, and (iii) set D with R2 = 0.6899, while set C was correlated with a three parameter equation with R(2) = 0.9432. These descriptors for predicting the melting points of the imidazolium and benzimidazolium bromides were based on the size and electrostatic interactions in the cations.

  8. Magnesium Lewis Acid Assisted Oxidative Bromoetherification Involving Bromine Transfer from Alkyl Bromides with Aldehydes by Umpolung of Bromide.

    PubMed

    Moriyama, Katsuhiko; Nishinohara, Chihiro; Togo, Hideo

    2016-08-16

    An oxidative bromoetherification involving a bromine transfer from alkyl bromides upon reacting them with aldehydes in a Grignard reaction with a concurrent oxidation of bromide was developed to provide substituted tetrahydrofurans in high yields. This reaction, which proceeds through two types of bromine transfer, was promoted by the addition of a Brønsted acid. Mechanistic studies suggested that a magnesium Lewis acid activates hypobromate, which is generated in situ from the reaction of bromide and Oxone to improve the electrophilicity of the bromonium ion (Br(+) ) for the oxidative bromoetherification of alkenyl alcohols. Furthermore, the magnesium Lewis acid catalyzed oxidative bromoetherification of an alkenyl alcohol proceeded to provide a cyclization product in 92 % yield. PMID:27304660

  9. Magnesium Lewis Acid Assisted Oxidative Bromoetherification Involving Bromine Transfer from Alkyl Bromides with Aldehydes by Umpolung of Bromide.

    PubMed

    Moriyama, Katsuhiko; Nishinohara, Chihiro; Togo, Hideo

    2016-08-16

    An oxidative bromoetherification involving a bromine transfer from alkyl bromides upon reacting them with aldehydes in a Grignard reaction with a concurrent oxidation of bromide was developed to provide substituted tetrahydrofurans in high yields. This reaction, which proceeds through two types of bromine transfer, was promoted by the addition of a Brønsted acid. Mechanistic studies suggested that a magnesium Lewis acid activates hypobromate, which is generated in situ from the reaction of bromide and Oxone to improve the electrophilicity of the bromonium ion (Br(+) ) for the oxidative bromoetherification of alkenyl alcohols. Furthermore, the magnesium Lewis acid catalyzed oxidative bromoetherification of an alkenyl alcohol proceeded to provide a cyclization product in 92 % yield.

  10. Solution properties and emulsification properties of amino acid-based gemini surfactants derived from cysteine.

    PubMed

    Yoshimura, Tomokazu; Sakato, Ayako; Esumi, Kunio

    2013-01-01

    Amino acid-based anionic gemini surfactants (2C(n)diCys, where n represents an alkyl chain with a length of 10, 12, or 14 carbons and "di" and "Cys" indicate adipoyl and cysteine, respectively) were synthesized using the amino acid cysteine. Biodegradability, equilibrium surface tension, and dynamic light scattering were used to characterize the properties of gemini surfactants. Additionally, the effects of alkyl chain length, number of chains, and structure on these properties were evaluated by comparing previously reported gemini surfactants derived from cystine (2C(n)Cys) and monomeric surfactants (C(n)Cys). 2C(n)diCys shows relatively higher biodegradability than does C(n)Cys and previously reported sugar-based gemini surfactants. Both critical micelle concentration (CMC) and surface tension decrease when alkyl chain length is increased from 10 to 12, while a further increase in chain length to 14 results in increased CMC and surface tension. This indicates that long-chain gemini surfactants have a decreased aggregation tendency due to the steric hindrance of the bulky spacer as well as premicelle formation at concentrations below the CMC and are poorly packed at the air/water interface. Formation of micelles (measuring 2 to 5 nm in solution) from 2C(n)diCys shows no dependence on alkyl chain length. Further, shaking the mixtures of aqueous 2C(n)diCys surfactant solutions and squalane results in the formation of oil-in-water type emulsions. The highly stable emulsions are formed using 2C₁₂diCys or 2C₁₄diCys solution and squalane in a 1:1 or 2:1 volume ratio.

  11. Observations Of The LCROSS Impact With NIFS On The Gemini North Telescope

    NASA Astrophysics Data System (ADS)

    Roth, Katherine; Stephens, A. W.; Trujillo, C. A.; McDermid, R. M.; Woodward, C. E.; Walls, B. D.; Coulson, D. M.; Matulonis, A. C.; Ball, J. G.; Wooden, D. H.

    2010-01-01

    The Lunar CRater Observation and Sensing Satellite (LCROSS) Centaur rocket impacted a permanently shadowed crater near the south pole of the Moon at 11:31 UTC 2009 October 09. Gemini, one of several telescopes in a coordinated network observing the impact, conducted observations using NIFS to obtain 3D K-band imaging spectroscopy to detect water ice in the ejected plume of material. The spectral slope of the NIFS data can constrain the grain size and height distribution as the plume evolves, measuring the total mass and the water ice concentration in the plume. These observations provided an engineering challenge for Gemini, including the need to track non-sidereal with constantly changing track rates and guide on small bright moon craters, in order to keep the impact site within the NIFS field-of-view. High quality images taken by GMOS-N, NIRI and the acquisition camera during engineering periods at specific lunar libration and illumination were also used by the LCROSS ground based observing team to supplement slit positioning and offset plans for other ground based observatories. LCROSS mission support and engineering has resulted in improved telescope functionality for non-sidereal targets, including the ability to upload and import target ephemerides directly into the TCS, starting in semester 2010B. In this poster we present the engineering results and observing improvements which will facilitate enhanced user capabilities of the Gemini telescopes arising from the intensive LCROSS support challenge. Gemini Observatory is operated by AURA, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the NSF (United States), the STFC (United Kingdom), the NRC (Canada), CONICYT (Chile), the ARC (Australia), Ministério da Ciência e Tecnologia (Brazil), and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina). In part this research was supported by NASA through contracts to SWRI and NSF grant AST-0706980 to the U

  12. Growth Behavior, Geometrical Shape, and Second CMC of Micelles Formed by Cationic Gemini Esterquat Surfactants.

    PubMed

    Bergström, L Magnus; Tehrani-Bagha, Alireza; Nagy, Gergely

    2015-04-28

    Micelles formed by novel gemini esterquat surfactants have been investigated with small-angle neutron scattering (SANS). The growth behavior of the micelles is found to differ conspicuously depending on the length of the gemini surfactant spacer group. The gemini surfactant with a long spacer form rather small triaxial ellipsoidal tablet-shaped micelles that grow weakly with surfactant concentration in the entire range of measured concentrations. Geminis with a short spacer, on the other hand, form weakly growing oblates or tablets at low concentrations that start to grow much more strongly into polydisperse rodlike or wormlike micelles at higher concentrations. The latter behavior is consistent with the presence of a second CMC that marks the transition from the weakly to the strongly growing regime. It is found that the growth behavior in terms of aggregation number as a function of surfactant concentration always appear concave in weakly growing regimes, while switching to convex behavior in strongly growing regimes. As a result, we are able to determine the second CMC of the geminis with short spacer by means of suggesting a rather precise definition of it, located at the point of inflection of the growth curve that corresponds to the transition from concave to convex growth behavior. Our SANS results are rationalized by comparison with the recently developed general micelle model. In particular, this theory is able to explain and reproduce the characteristic appearances of the experimental growth curves, including the presence of a second CMC and the convex strongly growing regime beyond. By means of optimizing the agreement between predictions from the general micelle model and results from SANS experiments, we are able to determine the three bending elasticity constants spontaneous curvature, bending rigidity, and saddle-splay constant for each surfactant. PMID:25835031

  13. Nickel-Catalyzed Reductive Cross-Coupling of Aryl Bromides with Alkyl Bromides: Et3N as the Terminal Reductant.

    PubMed

    Duan, Zhengli; Li, Wu; Lei, Aiwen

    2016-08-19

    Reductive cross-coupling has emerged as a direct method for the construction of carbon-carbon bonds. Most cobalt-, nickel-, and palladium-catalyzed reductive cross-coupling reactions to date are limited to stoichiometric Mn(0) or Zn(0) as the reductant. One nickel-catalyzed cross-coupling paradigm using Et3N as the terminal reductant is reported. By using this photoredox catalysis and nickel catalysis approach, a direct Csp(2)-Csp(3) reductive cross-coupling of aryl bromides with alkyl bromides is achieved under mild conditions without stoichiometric metal reductants. PMID:27472556

  14. REVIEW OF CONTROL OPTIONS FOR METHYL BROMIDE IN COMMODITY TREATMENT

    EPA Science Inventory

    The report describes recent developments in the control of methyl bromide (MeBr) and discusses technical considerations and requirements for and economic feasibility of recovery. (NOTE: MeBr, fumigant for agricultural commodities, is an ozone depleting chemical. The U.S. EPA has ...

  15. Pancuronium bromide induced joint contractures in the newborn.

    PubMed Central

    Sinha, S K; Levene, M I

    1984-01-01

    We report three infants paralysed with pancuronium bromide as an adjunct to mechanical ventilation, who developed multiple joint contractures. In two term infants, gentamicin and phenobarbitone given together with pancuronium may have potentiated its effect, and in one preterm infant contractures, which became more severe after paralysis, were present at birth. PMID:6696501

  16. Nickel-Catalyzed Reductive Amidation of Unactivated Alkyl Bromides.

    PubMed

    Serrano, Eloisa; Martin, Ruben

    2016-09-01

    A user-friendly, nickel-catalyzed reductive amidation of unactivated primary, secondary, and tertiary alkyl bromides with isocyanates is described. This catalytic strategy offers an efficient synthesis of a wide range of aliphatic amides under mild conditions and with an excellent chemoselectivity profile while avoiding the use of stoichiometric and sensitive organometallic reagents. PMID:27357076

  17. On the existence of 'L-alanine cadmium bromide'.

    PubMed

    Srinivasan, Bikshandarkoil R

    2013-12-01

    It is argued that the recently reported nonlinear optical crystal L-alanine cadmium bromide, grown by slow solvent evaporation method at room temperature [P. Ilayabarathi, J. Chandrasekaran, Spectrochim. Acta 96A (2012) 684-689] is the well-known L-alanine crystal. The isolation of L-alanine crystal is explained due to fractional crystallization.

  18. Methyl bromide phase out could affect future reforestation efforts

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Methyl bromide has long been an integral component in producing healthy tree seedlings in forest nurseries of California, Idaho, Montana, Oregon and Washington. The fumigant was supposed to be completely phased out of use in the United States of America by 2005, but many forest nurseries continue to...

  19. Investigation of bromide's spectra by high resolution UV-laser

    NASA Astrophysics Data System (ADS)

    Zhang, Jin; Ma, Jian-guo

    2011-12-01

    Experimental investigation has been carried out for dissociation/ionisation of methyl bromide using time of flight mass spectrometer, then, the mass signals were assigned to H+, CHm+ (m= 0-3), iBr+ (i = 79, 81), and the main processes of multi-photon ionization and dissociation of CH3Br were given.

  20. Ipratropium bromide spray as treatment for sialorrhea in Parkinson's disease.

    PubMed

    Thomsen, Teri R; Galpern, Wendy R; Asante, Abena; Arenovich, Tamara; Fox, Susan H

    2007-11-15

    Sialorrhea is a significant problem in advanced Parkinson's disease (PD). Current treatment options include systemic anticholinergics which frequently cause side effects. We hypothesized that sublingual application of ipratropium bromide spray, an anticholinergic agent that does not cross the blood brain barrier, may reduce drooling without systemic side effects. We performed a randomized, double blind, placebo-controlled, crossover study in 17 subjects with PD and bothersome drooling. Patients were randomized to receive ipratropium bromide or placebo (one to two sprays, maximum of four times per day) for 2 weeks followed by a 1 week washout and crossover for further 2 weeks of treatment. The primary outcome was an objective measure of weight of saliva production. Secondary outcomes were subjective rating of severity and frequency of sialorrhoea using home diaries, United Parkinson's Disease Rating Scale (UPDRS) part II salivation subscore, parkinsonian disability using UPDRS, and adverse events. Ipratropium bromide spray had no significant effect on weight of saliva produced. There was a mild effect of treatment on subjective measures of sialorrhea. There were no significant adverse events. Ipratropium bromide spray was well tolerated in subjects with PD. Although it did not affect objective measures of saliva production, further studies in parkinsonism may be warranted.

  1. Depleting methyl bromide residues in soil by reaction with bases

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Despite generally being considered the most effective soil fumigant, methyl bromide (MeBr) use is being phased out because its emissions from soil can lead to stratospheric ozone depletion. However, a large amount is still currently used due to Critical Use Exemptions. As strategies for reducing the...

  2. EFFECT OF BROMIDE ION ON FORMATION OF HAAS DURING CHLORINATION

    EPA Science Inventory

    loacetic acids (HAAs) during chlorination and he effects of independent variables, including pH, reaction time, and chlorine dosage. Almost all of the indpendent loaetic acids (HAAs) during chlorin...designed to statistically evaluate the influence of bromide ion on the formatio...

  3. T-type Ca2+ channel modulation by otilonium bromide

    PubMed Central

    Strege, Peter R.; Sha, Lei; Beyder, Arthur; Bernard, Cheryl E.; Perez-Reyes, Edward; Evangelista, Stefano; Gibbons, Simon J.; Szurszewski, Joseph H.

    2010-01-01

    Antispasmodics are used clinically to treat a variety of gastrointestinal disorders by inhibition of smooth muscle contraction. The main pathway for smooth muscle Ca2+ entry is through L-type channels; however, there is increasing evidence that T-type Ca2+ channels also play a role in regulating contractility. Otilonium bromide, an antispasmodic, has previously been shown to inhibit L-type Ca2+ channels and colonic contractile activity. The objective of this study was to determine whether otilonium bromide also inhibits T-type Ca2+ channels. Whole cell currents were recorded by patch-clamp technique from HEK293 cells transfected with cDNAs encoding the T-type Ca2+ channels, CaV3.1 (α1G), CaV3.2 (α1H), or CaV3.3 (α1I) alpha subunits. Extracellular solution was exchanged with otilonium bromide (10−8 to 10−5 M). Otilonium bromide reversibly blocked all T-type Ca2+ channels with a significantly greater affinity for CaV3.3 than CaV3.1 or CaV3.2. Additionally, the drug slowed inactivation in CaV3.1 and CaV3.3. Inhibition of T-type Ca2+ channels may contribute to inhibition of contractility by otilonium bromide. This may represent a new mechanism of action for antispasmodics and may contribute to the observed increased clinical effectiveness of antispasmodics compared with selective L-type Ca2+ channel blockers. PMID:20203058

  4. Tests of Dynamic Scale Model of Gemini Capsule in the Langley 20-Foot Free-Spinning Tunnel

    NASA Technical Reports Server (NTRS)

    1962-01-01

    Tests of Dynamic Scale Model of Gemini Capsule in the Langley 20-Foot Free-Spinning Tunnel. The film shows three spin tunnel tests of a 1/20 scale model of the Gemini capsule. In the first test, the capsule spins freely. In tests 2 and 3, a drogue parachute is attached to the capsule. [Entire movie available on DVD from CASI as Doc ID 20070030989. Contact help@sti.nasa.gov

  5. 40 CFR 180.519 - Bromide ion and residual bromine; tolerances for residues.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Bromide ion and residual bromine... Tolerances § 180.519 Bromide ion and residual bromine; tolerances for residues. (a) General. The food additives, bromide ion and residual bromine, may be present in water, potable in accordance with...

  6. 40 CFR 180.519 - Bromide ion and residual bromine; tolerances for residues.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Bromide ion and residual bromine... Tolerances § 180.519 Bromide ion and residual bromine; tolerances for residues. (a) General. The food additives, bromide ion and residual bromine, may be present in water, potable in accordance with...

  7. 40 CFR 180.519 - Bromide ion and residual bromine; tolerances for residues.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Bromide ion and residual bromine... Tolerances § 180.519 Bromide ion and residual bromine; tolerances for residues. (a) General. The food additives, bromide ion and residual bromine, may be present in water, potable in accordance with...

  8. 40 CFR 180.519 - Bromide ion and residual bromine; tolerances for residues.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Bromide ion and residual bromine... Tolerances § 180.519 Bromide ion and residual bromine; tolerances for residues. (a) General. The food additives, bromide ion and residual bromine, may be present in water, potable in accordance with...

  9. 40 CFR 721.4090 - Ethanaminium, N-[bis(diethylamino)-methylene]-N-ethyl-, bromide.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Ethanaminium, N- -N-ethyl-, bromide... Substances § 721.4090 Ethanaminium, N- -N-ethyl-, bromide. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as ethanaminium, N- -N-ethyl-, bromide (PMN...

  10. 40 CFR 721.4090 - Ethanaminium, N-[bis(diethylamino)-methylene]-N-ethyl-, bromide.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Ethanaminium, N- -N-ethyl-, bromide... Substances § 721.4090 Ethanaminium, N- -N-ethyl-, bromide. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as ethanaminium, N- -N-ethyl-, bromide (PMN...

  11. Uptake of ozone to mixed sodium bromide/ citric acid solutions

    NASA Astrophysics Data System (ADS)

    Lee, Ming-Tao; Steimle, Emilie; Bartels-Rausch, Thorsten; Kato, Shunsuke; Lampimäki, Markus; Brown, Matthew; van Bokhoven, Jeroen; Nolting, Frithjof; Kleibert, Armin; Türler, Andreas; Ammann, Markus

    2013-04-01

    Sea-salt solution - air interfaces play an important role in the chemistry of the marine boundary layer. The reaction of ozone (O3) with bromide is of interest in the context of formation of photolabile halogens (Br2, BrCl) in the marine boundary layer. Recent experiments have suggested that the bromide oxidation rate is related to the surface concentration of bromide [1] and inversely related to the gas phase concentration of O3, an indication for a precursor mediated reaction at the surface [2]. So far, the effect of organics (such as those occurring at the ocean surface or in marine aerosols) on the reaction of O3 with bromide aerosols has not been studied yet. In our study we investigate the uptake kinetics of O3 to a mixed solution of sodium bromide (NaBr) and citric acid (CA), which represents highly oxidized organic compounds present in the environment, with a well-established coated wall flow tube technique, which leads to exposure of the film to O3 allowing the heterogeneous reactions to take place and the loss of O3 being measured. The results indicate that the uptake of O3 to the films with the higher bromide concentrations (0.34M and 4M) is independent of the gas phase concentration and roughly consistent with uptake limited by reaction in the bulk. For the lower bromide concentration (84mM), however, we observe a trend of the uptake coefficient to decrease with increasing O3 concentration, indicating an increasing importance of a surface reaction. In an attempt to constrain the kinetic data, we employed X-ray photoelectron spectroscopy (XPS) to get insight into the surface composition of the aqueous solution - air interface. Previous XPS studies have shown that halide ion concentrations are enhanced at the aqueous solution air interface [3-4], which likely promotes the surface reactions of bromide or iodide with O3. A first XPS study of ternary solutions of KI with butanol indicated the importance of specific interactions of the cation with the alcohol

  12. Efficient improvement of surface activity of tea saponin through Gemini-like modification by straightforward esterification.

    PubMed

    Feng, Jin; Chen, Ying; Liu, Xin; Liu, Songbai

    2015-03-15

    Novel strategy of Gemini-like modification has been applied in development of new nonionic surfactants, tea saponin esters, with enhanced surface activity by simple esterification. Tea saponin was treated with acyl chlorides of different chain length and different ratio of tea saponin and acyl chloride under alkaline condition. The structures of tea saponin esters were analysed and confirmed by FT-IR, NMR and ESI-MS. Surface activity investigation revealed that esterification with the chain length of C12 and C14 and the ratio of 1:4 to 1:6 produced superior surface activity compared with tea saponin. The exceptional surface activity of the new surfactants suggested their great potential application in food industry as green surfactants due to their environmental benign nature as well as simple and inexpensive preparation. The strategy of Gemini-like modification will facilitate development of green surfactants based on natural resources.

  13. A new MOS mask cutter facility at Gemini/Cerro Tololo observatories

    NASA Astrophysics Data System (ADS)

    Wyman, Robert T.; Trancho, Gelys; Tighe, Roberto

    2010-07-01

    The installation and commissioning of a new laser cutter facility in La Serena, Chile is a cooperative effort between Gemini Observatory and the Cerro Tololo Inter-American Observatory. This system enables the cutting of aluminum and carbon fiber slit masks for three multi-object spectrographs operating in Chile: GMOS-S, Flamingos-2, and Goodman spectrograph. Selection of the new laser cutter tool was based on slit mask specifications developed for two materials. Prior to the commissioning all slit mask production was performed at Gemini's Northern base facility with a similar laser cutter system. The new facility supports two observatories and enhances the capabilities for both. This paper will discuss the observatory arrangement with respect to mask data tracking and handling. The laser system and facility will be discussed along with mask cutting performance, process development and manufacturing methods.

  14. Integrating the Galileoscope into Successfully Established as Well as New Outreach Programs at Gemini Observatory

    NASA Astrophysics Data System (ADS)

    Harvey, J.; Michaud, P.; Slater, T.; Slater, S.; Goldstein, J.

    2011-09-01

    The annual Journey through the Universe program is a flagship Gemini public education/outreach event that engages the public, teachers, astronomers, engineers, and thousands of local students and staff from all of the Mauna Kea Observatories. Now going into its seventh year in Hawaii, the 2010 program has integrated the Galileoscope as an integral part of the ten-day program with teacher workshops, classroom telescope kits, and a new teacher resource package developed for the program. Through the generous donation of Galileoscopes from the Ric and Jean Edelman Foundation and the Astronomical Society of the Pacific, each Project/Family Astro site received Galileoscopes. Each family participating in Gemini's Family Astro event and training program will receive a Galileoscope to take home. Workshops will be offered to the Girl and Boy scouts, the Boys and Girls Club of Hawaii, the County of Hawaii's Department of Parks and Recreation's summer programs, and other community organizations.

  15. Topical Non-Invasive Gene Delivery using Gemini Nanoparticles in Interferon-gamma-deficient Mice

    SciTech Connect

    Badea,I.; Wettig, S.; Verrall, R.; Foldvari, M.

    2007-01-01

    Cutaneous gene therapy, although a promising approach for many dermatologic diseases, has not progressed to the stage of clinical trials, mainly due to the lack of an effective gene delivery system. The main objective of this study was to construct and evaluate gemini nanoparticles as a topical formulation for the interferon gamma (IFN-{gamma}) gene in an IFN-{gamma}-deficient mouse model. Nanoparticles based on the gemini surfactant 16-3-16 (NP16-DNA) and another cationic lipid cholesteryl 3{beta}-(-N-[dimethylamino-ethyl] carbamate) [Dc-chol] (NPDc-DNA) were prepared and characterized. Zetasizer measurement indicated a bimodal distribution of 146 and 468 nm average particle sizes for the NP16-DNA ({zeta}-potential +51 mV) nanoparticles and monomodal distribution of 625 nm ({zeta}-potential +44 mV) for the NPDc-DNA. Circular dichroism studies showed that the gemini surfactant compacted the plasmid more efficiently compared to the Dc-chol. Small-angle X-ray scattering measurements revealed structural polymorphism in the NP16-DNA nanoparticles, with lamellar and Fd3m cubic phases present, while for the NPDc-DNA two lamellar phases could be distinguished. In vivo, both topically applied nanoparticles induced higher gene expression compared to untreated control and naked DNA (means of 0.480 and 0.398 ng/cm{sup 2} vs 0.067 and 0.167 ng/cm{sup 2}). However, treatment with NPDc-DNA caused skin irritation, and skin damage, whereas NP16-DNA showed no skin toxicity. In this study, we demonstrated that topical cutaneous gene delivery using gemini surfactant-based nanoparticles in IFN-{gamma}-deficient mice was safe and may provide increased gene expression in the skin due to structural complexity of NP16 nanoparticles (lamellar-cubic phases).

  16. Questions and Answers for Ken Thomas' "Intra-Extra Vehicular Activity Russian and Gemini Spacesuits" Presentation

    NASA Technical Reports Server (NTRS)

    Thomas, Kenneth S.

    2016-01-01

    Kenneth Thomas will discuss the Intra-Extra Vehicular Activity Russian & Gemini spacesuits. While the United States and Russia adapted to existing launch- and reentry-type suits to allow the first human ventures into the vacuum of space, there were differences in execution and capabilities. Mr. Thomas will discuss the advantages and disadvantages of this approach compared to exclusively intravehicular or extra-vehicular suit systems.

  17. Arabian Peninsula and northeast Africa as seen from Gemini 11 spacecraft

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Arabian Peninsula (on left) and northeast Africa (on right) as seen from the Gemini 11 spacecraft at an altitude of 340 nautical miles during its 27th revolution of the earth, looking southeast. Saudia Arabia, South Arabia, Yemen and Aden Protectorate are at left. At bottom right is Ethiopia. French Somaliland is in center on right shore. Somali is at upper right. Body of water at bottom is Red Sea. Gulf of Aden is in center; and at top left is Indian Ocean.

  18. The Gemini NICI Planet-Finding Campaign: The Companion Detection Pipeline

    NASA Astrophysics Data System (ADS)

    Wahhaj, Zahed; Liu, Michael C.; Biller, Beth A.; Nielsen, Eric L.; Close, Laird M.; Hayward, Thomas L.; Hartung, Markus; Chun, Mark; Ftaclas, Christ; Toomey, Douglas W.

    2013-12-01

    We present high-contrast image processing techniques used by the Gemini NICI Planet-Finding Campaign to detect faint companions to bright stars. The Near-Infrared Coronographic Imager (NICI) is an adaptive optics instrument installed on the 8 m Gemini South telescope, capable of angular and spectral difference imaging and specifically designed to image exoplanets. The Campaign data pipeline achieves median contrasts of 12.6 mag at 0.''5 and 14.4 mag at 1'' separation, for a sample of 45 stars (V = 4.3-13.9 mag) from the early phase of the campaign. We also present a novel approach to calculating contrast curves for companion detection based on 95% completeness in the recovery of artificial companions injected into the raw data, while accounting for the false-positive rate. We use this technique to select the image processing algorithms that are more successful at recovering faint simulated point sources. We compare our pipeline to the performance of the Locally Optimized Combination of Images (LOCI) algorithm for NICI data and do not find significant improvement with LOCI. Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the Science and Technology Facilities Council (United Kingdom), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência e Tecnologia (Brazil) and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina).

  19. Aluminum electroplating on steel from a fused bromide electrolyte

    SciTech Connect

    Prabhat K. Tripathy; Laura A. Wurth; Eric J. Dufek; Toni Y. Gutknecht; Natalie J. Gese; Paula Hahn; Steven M. Frank; Guy L. Frederickson; J. Stephen Herring

    2014-08-01

    A quaternary bromide bath (LiBr–KBr–CsBr–AlBr3) was used to electro-coat aluminum on steel substrates. The electrolytewas prepared by the addition of AlBr3 into the eutectic LiBr–KBr–CsBr melt. A smooth, thick, adherent and shiny aluminum coating could be obtained with 80 wt.% AlBr3 in the ternary melt. The SEM photographs of the coated surfaces suggest the formation of thick and dense coatings with good aluminum coverage. Both salt immersion and open circuit potential measurement suggested that the coatings did display a good corrosionresistance behavior. Annealing of the coated surfaces, prior to corrosion tests, suggested the robustness of the metallic aluminum coating in preventing the corrosion of the steel surfaces. Studies also indicated that the quaternary bromide plating bath can potentially provide a better aluminumcoating on both ferrous and non-ferrous metals, including complex surfaces/geometries.

  20. Viscosity and density of some lower alkyl chlorides and bromides

    SciTech Connect

    Rutherford, W.M.

    1988-07-01

    A high-pressure capillary viscometer, used previously to measure the viscosity of methyl chloride was rebuilt to eliminate the first-order dependence of the measured viscosity on the value assumed for the density of the fluid being investigated. At the same time, the system was arranged so that part of the apparatus could be used to measure density by a volumetric displacement technique. Viscosity and density were measured for ethyl chloride, 1-chloropropane, 1-chlorobutane, methyl bromide, ethyl bromide, and 1-bromopropane. The temperature and pressure ranges of the experiments were 20-150 /sup 0/C and 0.27-6.99 MPa, respectively. The accuracy of the viscosity measurements was estimated to be +-1% and of the density measurements, +-0.2%.

  1. Preparation of ethyl magnesium bromide for regiospecific analysis of triacylglycerols.

    PubMed

    Ando, Yasuhiro; Tomita, Yuki; Haba, Yusuke

    2008-01-01

    This paper presents a procedure for preparation of a Grignard reagent, ethyl magnesium bromide, used for partial deacylation of triacylglycerols (TAG) in their regiospecific analysis. Magnesium turnings were reacted with ethereal solution of bromoethane in a screw-capped test tube to synthesize 2 mL of 1 M ethyl magnesium bromide. Continuously stirred with a vortex mixer, the reaction smoothly proceeded at room temperature. Regiospecific analysis of 1,3-distearoyl-2-oleoylglycerol using this product showed that fatty acid compositions of the sn-1(3) and sn-2 positions were contaminated by less than 2 mol% of fatty acids migrated from isomeric positions. The analyses of lard and cod liver/mackerel oil TAG showed typical distribution patterns of 16:0, 22:5n-3 and 22:6n-3 in pig and fish depot TAG. These results confirmed the view that the freshly prepared reagent is usable for regiospecific analysis of TAG.

  2. Study of ferroelectric characteristics of diisopropylammonium bromide films

    NASA Astrophysics Data System (ADS)

    Thirmal, C.; Biswas, P. P.; Shin, Y. J.; Noh, T. W.; Giridharan, N. V.; Venimadhav, A.; Murugavel, P.

    2016-09-01

    Organic molecular ferroelectrics are highly desirable due to their numerous advantages. In the present work, a thick film of diisopropylammonium bromide organic molecular ferroelectric is fabricated on the ITO/glass substrate. The grown film shows preferential orientation along the c-axis with a ferroelectric transition at 419 K. The piezoresponse force microscopic measurements are done in a dual ac resonance tracking mode for its switching characteristics. The amplitude and phase images of the oppositely written domain patterns exhibit a clear contrast with 180° phase difference. The dynamical spectroscopic studies reveal a butterfly loop in amplitude and hysteretic character of the phase which are the expected characteristics features of ferroelectrics. In addition, the macroscopic polarization versus electric field hysteresis gives an additional proof for ferroelectric character of the film with the maximum polarization of 3.5 μC/cm2. Overall, we have successfully fabricated diisopropylammonium bromide organic films and demonstrated its room temperature ferroelectric characteristics.

  3. Aluminium Electroplating on Steel from a Fused Bromide Electrolyte

    SciTech Connect

    Prabhat Tripathy; Laura Wurth; Eric Dufek; Toni Y. Gutknecht; Natalie Gese; Paula Hahn; Steven Frank; Guy Fredrickson; J Stephen Herring

    2014-08-01

    A quaternary bromide bath (LiBr-KBr-CsBr-AlBr3) was used to electro-coat aluminium on steel substrates. The electrolyte was prepared by the addition of AlBr3 into the eutectic LiBr-KBr-CsBr melt. A smooth, thick, adherent and shiny aluminium coating could be obtained with 80 wt.% AlBr3 in the ternary melt. The SEM photographs of the coated surfaces suggest the formation of thick and dense coatings with good aluminium coverage. Both salt immersion and open circuit potential measurement suggest that the coatings did display good corrosion-resistance behavior. Annealing of the coated surfaces, prior to corrosion tests, suggested the robustness of the metallic aluminium coating in preventing the corrosion of the steel surfaces. Studies also indicated that the quaternary bromide plating bath can potentially provide a better aluminium coating on both ferrous and non-ferrous metals, including complex surfaces/geometries.

  4. Gemini Spectroscopy of Galactic Bulge Sources: A Population of Hidden Accreting Binaries Revealed?

    NASA Astrophysics Data System (ADS)

    Wu, Jianfeng; Jonker, Peter; Torres, Manuel; Britt, Christopher; Johnson, Chris; Hynes, Robert I.; Greiss, Sandra; Steeghs, Danny; Maccarone, Tom; Heinke, Craig O.; Wevers, Thomas

    2015-01-01

    We present Gemini spectroscopy for 21 X-ray sources detected in the Galactic Bulge Survey (GBS), which aims to investigate X-ray binaries in the Galactic Bulge region. For the majority of the sources, we have obtained spectra of the objects that are likely the real optical counterparts to the X-ray sources. Line measurements, spectral classification, and radial velocity analysis were performed on the Gemini spectra. We discover a population of hidden accreting binaries whose Gemini spectra apparently show neither strong Hα emission nor Hα absorption. However, the residual spectra of some sources after subtracting the best-fit stellar spectroscopic templates contain a broad Hα emission line which likely originates in an accretion disk. These hidden accreting sources may constitute a substantial portion of the full accreting binary population. We also identify three likely candidates of eclipsing or high-inclination quiescent low-mass X-ray binaries based on their broad Hα emission line profile and/or their optical light curves. Significant Hα emission line variability was also observed for two GBS sources.

  5. Genetic diversity of Mexican brook lamprey Lampetra (Tetrapleurodon) geminis (Alvarez del Villar, 1966).

    PubMed

    Mejía, Omar; Polaco, Oscar J; Zúñiga, Gerardo

    2004-11-01

    Lampreys are the only surviving representatives of the oldest known vertebrates. The Mexican lamprey L. geminis (nonparasitic), is particularly interesting, because it is an endemic, biogeographical relict, and a threatened species. RAPD markers were used to describe genetic diversity in L. geminis. A total of 77 specimens were collected from five populations, three in the Río Grande de Morelia-Cuitzeo basin and two in the Río Duero-Lerma-Chapala basin, México. Eighty-eight RAPD markers were obtained from eight primers. Genetic diversity within each population was estimated using Shannon's index (S), heterozygosity (H) and gene diversity (h). These estimates revealed significant variation within populations, although a variance homogeneity test (HOMOVA) showed no significant differences among populations or between basins. Nei genetic distance values indicate a low genetic differentiation among populations. Analysis of molecular variance (AMOVA) indicates that most of the genetic diversity occurs within populations (91.4%), but that a statistically significant amount is found among populations (P < 0.001). Principal coordinates and cluster analyses of RAPD phenotypes show that specimens are not grouped by geographical origin. The genetic diversity found within L. geminis populations may be explained by its breeding system and an overlapping of generations. The scarce genetic differentiation among populations is likely to the low rate of DNA change that characterizes the lamprey group.

  6. Development and Commissioning of the Integral Field Spectrograph for the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Chilcote, Jeffrey K.; Larkin, J. E.; Planet Imager instrument, Gemini; science Teams

    2014-01-01

    The Gemini Planet Imager (GPI) is one of a new generation of instruments being built to directly image extrasolar planets in the outer solar systems of young main sequence stars. By combining a 1700-actuactor adaptive optics system, an apodized-pupil Lyot coronagraph, a precision interferometric infrared wavefront sensor, and an integral field spectrograph (IFS), GPI’s goal is more than an order of magnitude improvement in contrast compared to existing high contrast systems. This presentation focuses on the performance and characterization of the GPI IFS which is based on concepts from the OSIRIS instrument employed at Keck. Like OSIRIS, the IFS utilizes an infrared transmissive lenslet array to sample an approximate 2.7 x 2.7 arcsecond field of view at the diffraction limit of the Gemini Telescopes. The IFS provides over 36,000 simultaneous low-resolution (R ~ 45) spectra across five bands between 1 and 2.5μm. Alternatively, the dispersing element can be replaced with a Wollaston prism to provide broadband polarimetry of the same five filter bands. The IFS construction was based at the University of California, Los Angeles in collaboration with the Université de Montreal, Immervision and Lawrence Livermore National Laboratory. The IFS was integrated with the other components of GPI in the fall of 2011. GPI has recently finished Integration & Testing at the University of California, Santa Cruz, and has been shipped to Gemini South where it is undergoing post delivery acceptance testing.

  7. The survival of terrestrial microorganisms in space at orbital altitudes during Gemini satellite experiments.

    PubMed

    Hotchin, J; Lorenz, P; Hemenway, C L

    1968-01-01

    In a previous series of rocket- and satellite-borne experiments, microorganisms were exposed to space between altitudes of 60 to 460 km for periods between 3 minutes and 4 months. The results showed that some of the unprotected microorganisms survived the direct exposure for up to 17 hours. Complete survival was found when the microorganisms were shielded from nonpenetrating radiation. These results made it desirable to systematically study the lethal influence of the space environment on a wider spectrum of unprotected microorganisms over various exposure periods. This communication presents the results of exposure experiments on board the Gemini XII satellite. The microorganisms were dried on plastic coated aluminum plates using techniques which will be described elsewhere. During the flight of the Gemini XII space capsule, the microorganisms were directly exposed to space for approximately 6 1/2 hours. After the successful completion of the Gemini XII mission the payload was returned to the laboratory for elution and titration of the microorganisms using techniques described elsewhere. The results showed that again survival of some microorganisms had occurred. An attempt is made to integrate these results with data obtained in previously published experiments.

  8. Managing target of opportunity (ToO) observations in queue mode at Gemini Observatory

    NASA Astrophysics Data System (ADS)

    Roth, Katherine C.; Carrasco, E. Rodrigo; Miller, Bryan W.; Stephens, Andrew W.; Jørgensen, Inger; Rodgers, Bernadette

    2010-07-01

    Target of opportunity observations (ToO) are an integral part of multi-instrument queue operations at Gemini Observatory. ToOs comprise a significant fraction of the queue (20-25% of the highest ranking band) and with the advent of large survey telescopes (eg. Pan-STARRS, LSST) dedicated to searching for transient events this fraction may reasonably be expected to increase significantly in the coming years. While some important aspects of ToO execution at Gemini Observatory are managed automatically (eg. trigger alerts, data distribution), other areas such as duplications checking, scheduling and relative priority determination still require manual intervention. In order to increase efficiency and improve our commitment to ToOs and queue observing in general, these aspects need to be formalized and incorporated into improved phase 2 checking, automated queue scheduling and on-the-fly nightly plan generation software. We discuss the different flavors of ToOs supported at Gemini Observatory and how each kind is scheduled with respect to existing queue observations. We present ideas for formalizing these practices into a system of dynamical prioritization which automatically self adjusts as new ToO observations are triggered, high priority targets become endangered, and timing windows near expiration.

  9. Implementing an Education and Outreach Program for the Gemini Observatory in Chile.

    NASA Astrophysics Data System (ADS)

    Garcia, M. A.

    2006-08-01

    Beginning in 2001, the Gemini Observatory began the development of an innovative and aggressive education and outreach program at its Southern Hemisphere site in northern Chile. A principal focus of this effort is centered on local education and outreach to communities surrounding the observatory and its base facility in La Serena Chile. Programs are now established with local schools using two portable StarLab planetaria, an internet-based teacher exchange called StarTeachers and multiple partnerships with local educational institutions. Other elements include a CD-ROM-based virtual tour that allows students, teachers and the public to experience the observatory's sites in Chile and Hawaii. This virtual environment allows interaction using a variety of immersive scenarios such as a simulated observation using real data from Gemini. Pilot projects like "Live from Gemini" are currently being developed which use internet videoconferencing technologies to bring the observatory's facilities into classrooms at universities and remote institutions. Lessons learned from the implementation of these and other programs will be introduced and the challenges of developing educational programming in a developing country will be shared.

  10. Oceanic Uptake of Methyl Bromide: Implications for Oceanic Production

    NASA Astrophysics Data System (ADS)

    Yvon-Lewis, S. A.; Butler, J. H.; King, D. B.; Saltzman, E. S.; Tokarczyk, R.

    2002-12-01

    Methyl bromide (CH3Br) is a source of inorganic bromine (Br) in the stratosphere, where it contributes to the depletion of stratospheric ozone. Unlike the chlorofluorocarbons, which are entirely anthropogenic, methyl bromide has both natural and anthropogenic sources. At ~10 parts per trillion in the troposphere, methyl bromide is believed to be the single largest contributor of stratospheric Br. Once in the stratosphere, Br is approximately 50 times more effective in depleting stratospheric ozone than Cl. However, the budget for CH3Br remains largely unbalanced with known sinks outweighing sources by ~50%. With production and degradation occurring in the ocean, the ocean is both a source and a sink for CH3Br. The balance between production and degradation results in the net undersaturation of CH3Br that has been observed over much of the world's ocean with an estimated global net ocean sink ranging from -11 to -20 Gg/y [King et al., 2000 and references therein]. However, effects of climate change, such as changes in windspeed distribution or sea-surface temperature could alter this balance. Modeling the potential effect of such forcing on the net flux of this important trace gas requires an understanding of the factors controlling the distributions of production and degradation in the surface ocean. During three recent research cruises (North Atlantic, North Pacific, and Southern Ocean), CH3Br degradation rate constants were measured along with saturation anomalies. Here we incorporate these data into a gridded global box model to examine the distribution of oceanic production rates necessary to support the observations. King, D.B., J.H. Butler, S.A. Montzka, S.A. Yvon-Lewis, and J.W. Elkins, Implications of methyl bromide supersaturations in the temperate North Atlantic Ocean, J. of Geophys. Res., 105 (D15), 19763-19769, 2000.

  11. Problems with NIOSH method 2520 for methyl bromide

    SciTech Connect

    Tharr, D.

    1994-03-01

    The National Institute for Occupational Safety and Health (NIOSH) publishes the NIOSH Manual of Analytical Methods (NMAM), a collection of analytical methods for characterizing exposures to environmental chemicals. When an industrial hygienist selects a method to monitor worker exposure, it is important to remember that not all the methods in the NMAM have undergone the same level of evaluation, as the following case demonstrates. As part of an industrywide study of the health effects resulting from methyl bromide exposure in structural and agricultural applicators, NIOSH researchers conducted industrial hygiene monitoring for methyl bromide in Florida during July 1990. NIOSH method 2520 was used. This method recommends use of two charcoal tubes (400 mg/100 mg) in series, desorption with carbon disulfide, and analysis by gas chromatography with a flame ionization detector. Sampling results from these surveys indicated a capacity problem. A project was then initiated to determine the reason for the methyl bromide breakthrough that occurred during industrial hygiene monitoring. While conducting research to define and solve this problem, several other problems were identified: reduced adsorption capacity caused by high humidity, difficulty in preparing standard solutions, sample instability, change in recovery with loading, and insufficiently low quantitation limit. The addition of a drying tube to the sampling train, as well as changes to the analytical technique, to the desorption solvent, and to the time till analysis, resulted in an improved method for methyl bromide. This case study demonstrates the importance of noting the conditions under which a method was evaluated and the benefit of testing method performance under conditions likely to exist at a field site. 5 refs.

  12. The Thz Absorption of Methyl Bromide (CH_3BR)

    NASA Astrophysics Data System (ADS)

    Ramos, Marlon; Drouin, Brian J.

    2011-06-01

    The possibility of monitoring Methyl Bromide is of interest for both environmental and health concerns. It has an ozone depletion potential of 0.2% and falls under regulations of the Clean Air Act. Neurological effects from long term exposure may result from its major use as a pesticide. Recent improvements in microwave limb sounding at mm & submm wavelengths have resulted in retrievals of Methyl Chloride from atmospheric spectra. It is conceivable that Methyl Bromide would also be measurable by this technique. In an effort to extend and improve the previous work, the THz spectrum of Methyl Bromide has been measured at JPL. We used an isotopically enriched 13CH_3Br (90%) sample and recorded spectra from 750 - 1200 GHz. Our assignment covers the CH_379Br, CH_381Br, 13CH_379Br and 13CH_381Br isotopologues with J< 66 and K< 17 for the ground vibrational state. We plan to assign vibrational satellites and investigate possible perturbations near K =12 in the ground state.

  13. [Manometric effects of pinaverium bromide in irritable bowel syndrome].

    PubMed

    Soifer, L; Varela, E; Olmos, J

    1992-01-01

    The effects of pinaverium bromide on colonic motility were investigated in a controlled, controlled, cross-over study in 32 patients with irritable bowel syndrome. Constipation was clearly predominant in one group of 16 patients, and diarrhea in the other group of 16. Manometric measurements were taken of the colonic motor response generated by distention of a balloon inserted to the rectosigmoid junction. Measurements were taken before and one hour after ingestion of two tablets containing placebo or two tablets each containing 50 mg of pinaverium bromide. Following intake of placebo the motility index increased from the basal value in patients with constipation, and resistance to distention decreased in the diarrhea group. These changes were attributable to repetition of the mechanical stimulus within a relatively brief time lapse, or more probably to the ingestion of liquid which accompanied intake of tablets. Compared with placebo, pinaverium bromide induced inhibition of both effects. From the therapeutic point of view, the decrease in motility index seen in patients with irritable bowel syndrome and constipation is particularly interesting. PMID:1295286

  14. Oral teratogenicity studies of methyl bromide in rats and rabbits.

    PubMed

    Kaneda, M; Hojo, H; Teramoto, S; Maita, K

    1998-05-01

    Teratogenicity studies of methyl bromide, a widely used fumigant, were conducted in rats and rabbits. Methyl bromide was dissolved in corn oil and administered orally to groups of 24 copulated female Crj:CD (SD) rats at dose levels of 0 (corn oil), 3, 10 or 30 mg/kg/day on days 6-15 of gestation and to groups of 18 artificially inseminated female Kbl:JW rabbits at 0, 1, 3 or 10 mg/kg/day on days 6-18 of gestation. Maternal rats and rabbits were euthanized on respective days 20 and 27 of gestation. Foetuses were examined for survival, growth and teratological alterations. Maternal toxicity was evident in the high-dose groups for both species. In these groups, maternal body weight gains and food consumption were significantly decreased during the dosing and post-dosing periods. Necropsy of maternal rats also revealed erosive lesions in the stomach and the surrounding organs. However, no treatment-related adverse effects were found in foetuses of the treated groups for both rat and rabbit studies. These results led to the conclusion that methyl bromide was not foetotoxic or teratogenic to rat and rabbit foetuses up to dose levels of 30 and 10 mg/kg/day, respectively, at which maternal toxicity was evident for both species.

  15. Comparison of Heat and Bromide as Ground Water Tracers Near Streams

    USGS Publications Warehouse

    Constantz, J.; Cox, M.H.; Su, G.W.

    2003-01-01

    Heat and bromide were compared as tracers for examining stream/ground water exchanges along the middle reaches of the Santa Clara River, California, during a 10-hour surface water sodium bromide injection test. Three cross sections that comprise six shallow (<1 m) piezometers were installed at the upper, middle, and lower sections of a 17 km long study reach, to monitor temperatures and bromide concentrations in the shallow ground water beneath the stream. A heat and ground water transport simulation model and a closely related solute and ground water transport simulation model were matched up for comparison of simulated and observed temperatures and bromide concentrations in the streambed. Vertical, one-dimensional simulations of sediment temperature were fitted to observed temperature results, to yield apparent streambed hydraulic conductivities in each cross section. The temperature-based hydraulic conductivities were assigned to a solute and ground water transport model to predict sediment bromide concentrations, during the sodium bromide injection test. Vertical, one-dimensional simulations of bromide concentrations in the sediments yielded a good match to the observed bromide concentrations, without adjustment of any model parameters except solute dispersivities. This indicates that, for the spatial and temporal scales examined on the Santa Clara River, the use of heat and bromide as tracers provide comparable information with respect to apparent hydraulic conductivities and fluxes for sediments near streams. In other settings, caution should be used due to differences in the nature of conservative (bromide) versus nonconservative (heat) tracers, particularly when preferential flowpaths are present.

  16. Interaction between gaseous ozone and crystalline potassium bromide

    NASA Astrophysics Data System (ADS)

    Levanov, A. V.; Maksimov, I. B.; Isaikina, O. Ya.; Antipenko, E. E.; Lunin, V. V.

    2016-07-01

    The formation of nonvolatile products of the oxidation of a bromide ion during the interaction between gaseous ozone and powdered crystalline KBr is studied. It is found that potassium bromate KBrO3 is the main product of the reaction. The influence of major experimental factors (the duration of ozonation, the concentration of ozone, the humidity of the initial gas, and the temperature) on the rate of formation of bromate is studied. The effective constants of the formation of bromate during the interaction between O3 and Br- in a heterogeneous gas-solid body system and in a homogeneous aqueous solution are compared.

  17. Photodissociation of methyl chloride and methyl bromide in the atmosphere

    NASA Technical Reports Server (NTRS)

    Robbins, D. E.

    1976-01-01

    Methyl chloride (CH3Cl) and methyl bromide (CH3Br) have been suggested to be significant sources of the stratospheric halogens. The breakup of these compounds in the stratosphere by photodissociation or reaction with OH releases halogen atoms which catalytically destroy ozone. Experimental results are presented for ultraviolet photoabsorption cross sections of CH3Cl and CH3Br. Calculations are presented of loss rates for the methyl halides due to photodissociation and reaction with OH and of mixing ratios of these species in the stratosphere.

  18. Automated determination of bromide in waters by ion chromatography with an amperometric detector

    USGS Publications Warehouse

    Pyen, G.S.; Erdmann, D.E.

    1983-01-01

    An automated ion chromatograph, including a program controller, an automatic sampler, an integrator, and an amperometric detector, was used to develop a procedure for the determination of bromide in rain water and many ground waters. Approximately 10 min is required to obtain a chromatogram. The detection limit for bromide is 0.01 mg l-1 and the relative standard deivation is <5% for bromide concentrations between 0.05 and 0.5 mg l-1. Chloride interferes if the chloride-to-bromide ratio is greater than 1 000:1 for a range of 0.01-0.1 mg l-1 bromide; similarly, chloride interferes in the 0.1-1.0 mg l-1 range if the ratio is greater than 5 000:1. In the latter case, a maximum of 2 000 mg l-1 of chloride can be tolerated. Recoveries of known concentrations of bromide added to several samples, ranged from 97 to 110%. ?? 1983.

  19. Vesicles from pH-regulated reversible gemini amino-acid surfactants as nanocapsules for delivery.

    PubMed

    Lv, Jing; Qiao, Weihong; Li, Zongshi

    2016-10-01

    Reversible transition from micelles to vesicles by regulating pH were realized by gemini amino-acid surfactants N,N'-dialkyl-N,N'-diacetate ethylenediamine. Measurement results of ζ-potential at different pH and DLS at varying solvents revealed that the protonation between H(+) and double NCH2COO(-) groups (generating NH(+)CH2COO(-)), expressed as pKa1 and pKa2, is the key driving force to control the aggregation behaviors of gemini surfactant molecule. Effect of pH on the bilayer structure was studied in detail by using steady-state fluorescence spectroscopy of hydrophobic pyrene and Coumarin 153 (C153) respectively and fluorescence resonance energy transfer (FRET) from C153 to Rhodamine 6G (R6G). Various pH-regulated and pH-reversible self-assemblies were obtained in one surfactant system. Vitamin D3 was encapsulated in vesicle bilayers to form nano-VD3-capsules as VD3 supplement agent for health care products. By using the electrostatic attraction between Ca(2+) and double -COO(-) groups, nano-VD3-capsules with Ca(2+) coated outermost layers were prepared as a formulation for VD3 and calcium co-supplement agent. DLS and TEM were performed to check stability and morphology of the nano-capsules. It is concluded that the pH-regulated gemini amino-acid surfactants can be used to construct colloidal systems for delivering hydrophobic drugs or nutritions without lipids at human physiological pH level. PMID:27419647

  20. The interactions between cationic cellulose and Gemini surfactant in aqueous solution.

    PubMed

    Zhao, Shaojing; Cheng, Fa; Chen, Yu; Wei, Yuping

    2016-05-01

    Due to the extensive application of cationic cellulose in cosmetic, drug delivery and gene therapy, combining the improvement effect of surfactant-cellulose complexes, to investigate the properties of cellulose in aqueous solution is an important topic from both scientific and technical views. In this study, the phase behavior, solution properties and microstructure of Gemini surfactant sodium 5-nonyl-2-(4-(4-nonyl-2-sulfonatophenoxy)butoxy)phenyl sulfite (9-4-9)/cationic cellulose (JR400, the ammonium groups are directly bonded to the hydroxyethyl substituent with a degree substitution of 0.37) mixture was investigated using turbidity, fluorescence spectrophotometer and shear rheology techniques. As a control, the interaction of corresponding monovalent surfactant, sodium 2-ethoxy-5-nonylbenzenesulfonate (9-2) with JR400 in aqueous solution was also studied. Experimental results showed that 9-4-9/JR400 mixture has lower critical aggregation concentration (CAC) and critical micelle concentration (CMC) (about one order of magnitude) than 9-2/JR400 mixture. A low concentration of Gemini surfactant 9-4-9 appeared to induce an obvious micropolarity and viscosity value variation of the mixture, while these effects required a high concentration of corresponding monovalent one. Furthermore, dynamic light scattering (DLS) and transmission electron microscopy (TEM) measurements illuminated the formation and collapse procedure of network structure of the 9-4-9/JR400 mixture, which resulted in the increase and decrease of viscosity. These results suggest that the molecular structure of the surfactant has a great effect on its interaction with cationic cellulose. Moreover, the Gemini surfactant/cationic cellulose mixture may be used as a potencial stimuli-responsive drug delivery vector which not only load hydrophilic drugs, but also deliver hydrophobic substances. PMID:26876997

  1. Vesicles from pH-regulated reversible gemini amino-acid surfactants as nanocapsules for delivery.

    PubMed

    Lv, Jing; Qiao, Weihong; Li, Zongshi

    2016-10-01

    Reversible transition from micelles to vesicles by regulating pH were realized by gemini amino-acid surfactants N,N'-dialkyl-N,N'-diacetate ethylenediamine. Measurement results of ζ-potential at different pH and DLS at varying solvents revealed that the protonation between H(+) and double NCH2COO(-) groups (generating NH(+)CH2COO(-)), expressed as pKa1 and pKa2, is the key driving force to control the aggregation behaviors of gemini surfactant molecule. Effect of pH on the bilayer structure was studied in detail by using steady-state fluorescence spectroscopy of hydrophobic pyrene and Coumarin 153 (C153) respectively and fluorescence resonance energy transfer (FRET) from C153 to Rhodamine 6G (R6G). Various pH-regulated and pH-reversible self-assemblies were obtained in one surfactant system. Vitamin D3 was encapsulated in vesicle bilayers to form nano-VD3-capsules as VD3 supplement agent for health care products. By using the electrostatic attraction between Ca(2+) and double -COO(-) groups, nano-VD3-capsules with Ca(2+) coated outermost layers were prepared as a formulation for VD3 and calcium co-supplement agent. DLS and TEM were performed to check stability and morphology of the nano-capsules. It is concluded that the pH-regulated gemini amino-acid surfactants can be used to construct colloidal systems for delivering hydrophobic drugs or nutritions without lipids at human physiological pH level.

  2. New ester based gemini surfactants: the effect of different cationic headgroups on micellization properties and viscosity of aqueous micellar solution.

    PubMed

    Bhadani, Avinash; Tani, Misako; Endo, Takeshi; Sakai, Kenichi; Abe, Masahiko; Sakai, Hideki

    2015-07-15

    A new series of ester functionalized cationic gemini surfactants having different cationic headgroups (i.e. piperidinium, pyrrolidinium, morpholinium and quaternary ammonium) have been synthesized and characterized using NMR and Mass spectroscopy. These new gemini surfactants were investigated for their micellization and viscosity properties using surface tension, conductivity, fluorescence and rheology thechniques. The physicochemical properties of the aqueous surfactant system were influenced by polarity, size and the nature of cationic headgroups as the surface, thermodynamic and viscosity properties of these gemini surfactants were found to be dependent on the type of cationic headgroup. The current research finding establishes the structure-property relationship of the surfactant molecule specifically taking into account the dominant role displayed by the nature of the cationic headgroup. PMID:26145125

  3. Gemini: A hybrid plasma modelling capability for low pressure systems. User`s manual - V.1.7

    SciTech Connect

    Johannes, J.; Bartel, T.; Sears, D.; Payne, J.

    1996-10-01

    Gemini is the coupling of Icarus, the Sandia National Laboratories (SNL) 2-D Direct Simulation Monte Carlo (DMSC) code, to MPRES, the University of Houston 2-D finite element plasma reactor code. Thus, Gemini is not a stand alone code. The primary application of Gemini is the simulation of inductively coupled plasma reactors that operate at low pressures (< 10mtorr) where continuum formulations of the transport equations begin to break down. Plasma parameters (electron density (ne), electron temperature (Te) and electrostatic fields (Er and Ez)) are computed in MPRES and interpolated onto the DSMC grid. This allows transport of the neutrals and ions to be performed using the DSMC method while including electron impact reactions and field transport effects. A sample calculation including appropriate input files is given.

  4. Effects of pinaverium bromide and verapamil on the motility of the rat isolated colon.

    PubMed Central

    Baumgartner, A.; Drack, E.; Halter, F.; Scheurer, U.

    1985-01-01

    Pinaverium bromide was 30 times less potent than verapamil in inhibiting intraluminal pressure responses of in vitro rat colonic segments to barium chloride, acetylcholine, FK 33-824 or field stimulation. The inhibitory effects of both verapamil and pinaverium bromide on the pressure responses to field stimulation were antagonized similarly by exogenous calcium administration. These results support the concept that pinaverium bromide acts on calcium channels in the smooth muscle cell membrane. PMID:4052731

  5. Effects of pinaverium bromide and verapamil on the motility of the rat isolated colon.

    PubMed

    Baumgartner, A; Drack, E; Halter, F; Scheurer, U

    1985-09-01

    Pinaverium bromide was 30 times less potent than verapamil in inhibiting intraluminal pressure responses of in vitro rat colonic segments to barium chloride, acetylcholine, FK 33-824 or field stimulation. The inhibitory effects of both verapamil and pinaverium bromide on the pressure responses to field stimulation were antagonized similarly by exogenous calcium administration. These results support the concept that pinaverium bromide acts on calcium channels in the smooth muscle cell membrane. PMID:4052731

  6. The Renaissance of an Old Problem: Highly Regioselective Carboxylation of 2-Alkynyl Bromides with Carbon Dioxide.

    PubMed

    Miao, Bukeyan; Li, Gen; Ma, Shengming

    2015-11-23

    A steric effect-controlled, zinc-mediated carboxylation of different 2-alkynyl bromides under an atmospheric pressure of CO2 has been developed by careful tuning of different reaction parameters, including the metal, solvent, temperature, and additive. 2-Substituted 2,3-allenoic acids were afforded from primary 2-alkynyl bromides, whereas the carboxylation of secondary 2-alkynyl bromides yielded 3-alkynoic acids in decent yields. A rationale for the observed regioselectivity has been proposed.

  7. GEMINI/GeMS Observations Unveil the Structure of the Heavily Obscured Globular Cluster Liller 1.

    NASA Astrophysics Data System (ADS)

    Saracino, S.; Dalessandro, E.; Ferraro, F. R.; Lanzoni, B.; Geisler, D.; Mauro, F.; Villanova, S.; Moni Bidin, C.; Miocchi, P.; Massari, D.

    2015-06-01

    By exploiting the exceptional high-resolution capabilities of the near-IR camera GSAOI combined with the Gemini Multi-Conjugate Adaptive System at the GEMINI South Telescope, we investigated the structural and physical properties of the heavily obscured globular cluster Liller 1 in the Galactic bulge. We have obtained the deepest and most accurate color–magnitude diagram published so far for this cluster, reaching {{K}s}∼ 19 (below the main-sequence turnoff level). We used these data to redetermine the center of gravity of the system, finding that it is located about 2.″2 southeast from the literature value. We also built new star density and surface brightness profiles for the cluster and rederived its main structural and physical parameters (scale radii, concentration parameter, central mass density, total mass). We find that Liller 1 is significantly less concentrated (concentration parameter c=1.74) and less extended (tidal radius {{r}t}=298\\prime\\prime and core radius {{r}c}=5\\buildrel{\\prime\\prime}\\over{.} 39) than previously thought. By using these newly determined structural parameters, we estimated the mass of Liller 1 to be {{M}tot}=2.3+0.3-0.1× {{10}6} {{M}ȯ } ({{M}tot}=1.5+0.2-0.1× {{10}6} {{M}ȯ } for a Kroupa initial mass function), which is comparable to that of the most massive clusters in the Galaxy (ω Centari and Terzan 5). Also, Liller 1 has the second-highest collision rate (after Terzan 5) among all star clusters in the Galaxy, thus confirming that it is an ideal environment for the formation of collisional objects (such as millisecond pulsars). Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da

  8. The use of a high-order MEMS deformable mirror in the Gemini Planet Imager

    SciTech Connect

    Poyneer, L A; Bauman, B; Cornelissen, S; Jones, S; Macintosh, B; Palmer, D; Isaacs, J

    2010-12-17

    We briefly review the development history of the Gemini Planet Imager's 4K Boston Micromachines MEMS deformable mirror. We discuss essential calibration steps and algorithms to control the MEMS with nanometer precision, including voltage-phase calibration and influence function characterization. We discuss the integration of the MEMS into GPI's Adaptive Optics system at Lawrence Livermore and present experimental results of 1.5 kHz closed-loop control. We detail mitigation strategies in the coronagraph to reduce the impact of abnormal actuators on final image contrast.

  9. Comparación fotométrica en imágenes Gemini/GMOS:

    NASA Astrophysics Data System (ADS)

    Escudero, C. G.; Sesto, L. A.; González, N. M.; Faifer, F. R.; Smith Castelli, A.; Forte, J. C.

    2015-08-01

    We compare the performance and reliability of PSFEx and daophot ii in the construction and modeling of the Point Spread Function (PSF) on real images. Both methods were applied over photometric catalogs of globular cluster candidates in the elliptical galaxy NGC1395, generated with SExtractor on Gemini/GMOS images in the filters,,,. We use the PSF photometry obtained from both softwares to compare magnitudes, colour-colour and colour-magnitude diagrams. We also analyzed the new parameter spreadmodel used by SExtractor+PSFEx, which allows to separate point sources from extended objects.

  10. Implementation of modal combination rules for response spectrum analysis using GEMINI

    SciTech Connect

    Nukala, P K

    1999-06-01

    One of the widely used methodologies for describing the behavior of a structural system subjected to seismic excitation is response spectrum modal dynamic analysis. Several modal combination rules are proposed in the literature to combine the responses of individual modes in a response spectrum dynamic analysis. In particular, these modal combination rules are used to estimate the representative maximum value of a particular response of interest for design purposes. Furthermore, these combination rules also provide guidelines for combining the representative maximum values of the response obtained for each of the three orthogonal spatial components of an earthquake. This report mainly focuses on the implementation of different modal combination rules into GEMINI [I].

  11. GEMINI/GeMS Observations Unveil the Structure of the Heavily Obscured Globular Cluster Liller 1.

    NASA Astrophysics Data System (ADS)

    Saracino, S.; Dalessandro, E.; Ferraro, F. R.; Lanzoni, B.; Geisler, D.; Mauro, F.; Villanova, S.; Moni Bidin, C.; Miocchi, P.; Massari, D.

    2015-06-01

    By exploiting the exceptional high-resolution capabilities of the near-IR camera GSAOI combined with the Gemini Multi-Conjugate Adaptive System at the GEMINI South Telescope, we investigated the structural and physical properties of the heavily obscured globular cluster Liller 1 in the Galactic bulge. We have obtained the deepest and most accurate color-magnitude diagram published so far for this cluster, reaching {{K}s}˜ 19 (below the main-sequence turnoff level). We used these data to redetermine the center of gravity of the system, finding that it is located about 2.″2 southeast from the literature value. We also built new star density and surface brightness profiles for the cluster and rederived its main structural and physical parameters (scale radii, concentration parameter, central mass density, total mass). We find that Liller 1 is significantly less concentrated (concentration parameter c=1.74) and less extended (tidal radius {{r}t}=298\\prime\\prime and core radius {{r}c}=5\\buildrel{\\prime\\prime}\\over{.} 39) than previously thought. By using these newly determined structural parameters, we estimated the mass of Liller 1 to be {{M}tot}=2.3+0.3-0.1× {{10}6} {{M}⊙ } ({{M}tot}=1.5+0.2-0.1× {{10}6} {{M}⊙ } for a Kroupa initial mass function), which is comparable to that of the most massive clusters in the Galaxy (ω Centari and Terzan 5). Also, Liller 1 has the second-highest collision rate (after Terzan 5) among all star clusters in the Galaxy, thus confirming that it is an ideal environment for the formation of collisional objects (such as millisecond pulsars). Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da

  12. Gemini/GMOS imaging of globular cluster systems in five early-type galaxies

    NASA Astrophysics Data System (ADS)

    Faifer, Favio R.; Forte, Juan C.; Norris, Mark A.; Bridges, Terry; Forbes, Duncan A.; Zepf, Stephen E.; Beasley, Mike; Gebhardt, Karl; Hanes, David A.; Sharples, Ray M.

    2011-09-01

    In this paper, we present deep high-quality photometry of globular cluster systems (GCSs) belonging to five early-type galaxies, covering a range of mass and environment. Photometric data were obtained with the Gemini North and Gemini South telescopes in the filter passbands g', r' and i'. The combination of these filters with good seeing conditions allows an excellent separation between globular cluster (GC) candidates and unresolved field objects. In fact, our previously published spectroscopic data indicate a contamination level of only ˜10 per cent in our sample of GC candidates. Bimodal GC colour distributions are found in all five galaxies. Most of the GCSs appear bimodal even in the (g'-r') versus (r'-i') plane. A population of resolved/marginally resolved GC and ultracompact dwarf candidates was found in all the galaxies. A search for the so-called 'blue tilt' in the colour-magnitude diagrams reveals that NGC 4649 clearly shows this phenomenon, although no conclusive evidence was found for the other galaxies in the sample. This 'blue tilt' translates into a mass-metallicity relation given by Z∝M0.28 ±0.03. This dependence was found using a new empirical (g'-i') versus [Z/H] relation, which relies on an homogeneous sample of GC colours and metallicities. In this paper, we also explore the radial trends in both colour and surface density for the blue (metal-poor) and red (metal-rich) GC subpopulations. As usual, the red GCs show a steeper radial distribution than the blue GCs. Evidence of galactocentric colour gradients is found in some of the GCSs, which is more significant for the two S0 galaxies in the sample. Red GC subpopulations show similar colours and gradients to the galaxy halo stars in their inner region. A GC mean colour-galaxy luminosity relation, consistent with [Z/H]∝L0.26 ±0.08B, is present for the red GCs. Estimates of the total GC populations and specific frequency SN values are presented for NGC 3115, 3923 and 4649. Based on

  13. Transient neuromyopathy after bromide intoxication in a dog with idiopathic epilepsy

    PubMed Central

    2012-01-01

    A seven-year old Australian Shepherd, suffering from idiopathic epilepsy under treatment with phenobarbitone and potassium bromide, was presented with generalised lower motor neuron signs. Electrophysiology and muscle-nerve biopsies revealed a neuromyopathy. The serum bromide concentration was increased more than two-fold above the upper reference value. Clinical signs disappeared after applying diuretics and reducing the potassium bromide dose rate. This is the first case report describing electrophysiological and histopathological findings associated with bromide induced lower motor neuron dysfunction in a dog. PMID:23216950

  14. The in vitro and in vivo profile of aclidinium bromide in comparison with glycopyrronium bromide.

    PubMed

    Gavaldà, Amadeu; Ramos, Israel; Carcasona, Carla; Calama, Elena; Otal, Raquel; Montero, José Luis; Sentellas, Sonia; Aparici, Monica; Vilella, Dolors; Alberti, Joan; Beleta, Jorge; Miralpeix, Montserrat

    2014-08-01

    This study characterised the in vitro and in vivo profiles of two novel long-acting muscarinic antagonists, aclidinium bromide and glycopyrronium bromide, using tiotropium bromide and ipratropium bromide as comparators. All four antagonists had high affinity for the five muscarinic receptor sub-types (M1-M5); aclidinium had comparable affinity to tiotropium but higher affinity than glycopyrronium and ipratropium for all receptors. Glycopyrronium dissociated faster from recombinant M3 receptors than aclidinium and tiotropium but more slowly than ipratropium; all four compounds dissociated more rapidly from M2 receptors than from M3 receptors. In vitro, aclidinium, glycopyrronium and tiotropium had a long duration of action at native M3 receptors (>8 h versus 42 min for ipratropium). In vivo, all compounds were equi-potent at reversing acetylcholine-induced bronchoconstriction. Aclidinium, glycopyrronium and ipratropium had a faster onset of bronchodilator action than tiotropium. Aclidinium had a longer duration of action than glycopyronnium (time to 50% recovery of effect [t½ offset] = 29 h and 13 h, respectively); these compare with a t½ offset of 64 h and 8 h for tiotropium and ipratropium, respectively. Aclidinium was less potent than glycopyrronium and tiotropium at inhibiting salivation in conscious rats (dose required to produce half-maximal effect [ED50] = 38, 0.74 and 0.88 μg/kg, respectively) and was more rapidly hydrolysed in rat, guinea pig and human plasma compared with glycopyrronium or tiotropium. These results indicate that while aclidinium and glycopyrronium are both potent antagonists at muscarinic receptors with similar kinetic selectivity for M3 receptors versus M2, aclidinium has a longer dissociation half-life at M3 receptors and a longer duration of bronchodilator action in vivo than glycopyrronium. The rapid plasma hydrolysis of aclidinium, coupled to its kinetic selectivity, may confer a reduced propensity for systemic

  15. Bromoform formation in ozonated groundwater containing bromide and humic substances

    SciTech Connect

    Cooper, W.J.; Amy, G.L.; Moore, C.A.; Zika, R.G.

    1986-01-01

    The effect of bromide ion, organic carbon concentration (natural aquatic humic substances), pH, and solar irradiation on the formation of bromoform in ozonated groundwater has been studied. The studies were conducted on four unique samples of groundwater taken from different regions of the Biscayne Aquifer in southern Florida. All other conditions being equal, increases in bromide ion concentrations resulted in increases in CHBr/sub 3/ formation. In three of the four samples, CHBr/sub 3/ formation decreased as the pH level increased from 5 to 9. The fourth sample exhibited an opposite trend whereby the CHBr/sub 3/ concentration increased with increasing pH. Bromoform concentration increased with increased O/sub 3/ concentration over an ozone dosage range of 3.4 to 6.7 mg/L. Ozonated samples placed in sunlight immediately after ozone addition showed a decrease in the formation of CHBr/sub 3/ presumably due to the photodecomposition of HOBr/OBr.

  16. Validation of an automated fluorescein method for determining bromide in water

    USGS Publications Warehouse

    Fishman, M. J.; Schroder, L.J.; Friedman, L.C.

    1985-01-01

    Surface, atmospheric precipitation and deionized water samples were spiked with ??g l-1 concentrations of bromide, and the solutions stored in polyethylene and polytetrafluoroethylene bottles. Bromide was determined periodically for 30 days. Automated fluorescein and ion chromatography methods were used to determine bromide in these prepared samples. Analysis of the data by the paired t-test indicates that the two methods are not significantly different at a probability of 95% for samples containing from 0.015 to 0.5 mg l-1 of bromide. The correlation coefficient for the same sets of paired data is 0.9987. Recovery data, except for the surface water samples to which 0.005 mg l-1 of bromide was added, range from 89 to 112%. There appears to be no loss of bromide from solution in either type of container.Surface, atmospheric precipitation and deionized water samples were spiked with mu g l** minus **1 concentrations of bromide, and the solutions stored in polyethylene and polytetrafluoroethylene bottles. Bromide was determined periodically for 30 days. Automated fluorescein and ion chromatography methods were used to determine bromide in these prepared samples. Analysis of the data by the paired t-test indicates that the two methods are not significantly different at a probability of 95% for samples containing from 0. 015 to 0. 5 mg l** minus **1 of bromide. The correlation coefficient for the same sets of paired data is 0. 9987. Recovery data, except for the surface water samples to which 0. 005 mg l** minus **1 of bromide was added, range from 89 to 112%. Refs.

  17. The distribution of bromide in water in the Floridan aquifer system, Duval County, northeastern Florida

    USGS Publications Warehouse

    German, E.R.; Taylor, G.F.

    1995-01-01

    Although Duval County, Florida, has ample ground-water resources for public supply, the potential exists for a problem with excessive disinfectant by-products. These disinfectant by-products result from the treatment of raw water containing low concentrations of bromide and naturally occurring organic compounds. Because of this potential problem, the relation of bromide concentrations to aquifer tapped, well location and depth, and chemical characteristics of water in the Floridan aquifer system underlying Duval County were studied to determine if these relations could be applied to delineate water with low-bromide concentrations for future supplies. In 1992, water samples from 106 wells that tap the Floridan aquifer system were analyzed for bromide and major dissolved constituents. A comparison of bromide concentrations from the 1992 sampling with data from earlier studies (1979-80) indicates that higher bromide concentrations were detected during the earlier studies. The difference between the old and new data is probably because of a change in analytical methodology in the analysis of samples. Bromide concentrations exceeded the detection limit (0.10 milligrams per liter) in water from 28 of the 106 wells (26 percent) sampled in 1992. The maximum concentration was 0.56 milligrams per liter. There were no relations between bromide and major dissolved constituents, well depth, or aquifer tapped that would be useful for determining bromide concentrations. Areal patterns of bromide occurrence are not clearly defined, but areas with relatively high bromide concentrations tend to be located in a triangular area near the community of Sunbeam, Florida, and along the St. Johns River throughout Duval County.

  18. The Gemini NICI planet-finding campaign: The companion detection pipeline

    SciTech Connect

    Wahhaj, Zahed; Liu, Michael C.; Nielsen, Eric L.; Chun, Mark; Ftaclas, Christ; Biller, Beth A.; Close, Laird M.; Hayward, Thomas L.; Hartung, Markus

    2013-12-10

    We present high-contrast image processing techniques used by the Gemini NICI Planet-Finding Campaign to detect faint companions to bright stars. The Near-Infrared Coronographic Imager (NICI) is an adaptive optics instrument installed on the 8 m Gemini South telescope, capable of angular and spectral difference imaging and specifically designed to image exoplanets. The Campaign data pipeline achieves median contrasts of 12.6 mag at 0.''5 and 14.4 mag at 1'' separation, for a sample of 45 stars (V = 4.3-13.9 mag) from the early phase of the campaign. We also present a novel approach to calculating contrast curves for companion detection based on 95% completeness in the recovery of artificial companions injected into the raw data, while accounting for the false-positive rate. We use this technique to select the image processing algorithms that are more successful at recovering faint simulated point sources. We compare our pipeline to the performance of the Locally Optimized Combination of Images (LOCI) algorithm for NICI data and do not find significant improvement with LOCI.

  19. Role of spacer length in interaction between novel gemini imidazolium surfactants and Rhizopus oryzae lipase.

    PubMed

    Adak, Sunita; Datta, Sougata; Bhattacharya, Santanu; Banerjee, Rintu

    2015-11-01

    An insight into the effects of new ionic liquid-type gemini imidazolium cationic surfactants on the structure and function of the lipases is of prime importance for their potential application. Changes in the activity, stability and structure of Rhizopus oryzae lipase in the presence of novel gemini surfactants, [C16-3-C16im]Br2 and [C16-12-C16im]Br2 were probed in the present study. Surfactant with shorter spacer length, [C16-3-C16im]Br2 was found to be better in improving the hydrolytic activity and thermal stability of the lipase. For both the surfactants, activation was concentration dependent. CD spectroscopy results showed a decrease in α-helix and an increase in β-sheet content in the presence of these surfactants. A higher structural change observed in presence of [C16-12-C16im]Br2 correlated with lower enzyme activity. Isothermal titration calorimetric studies showed the binding to be spontaneous in nature based on sequential two site binding model. The forces involved in binding were found to differ for the two surfactants proving that the spacer length is an important factor which governs the interaction. These surfactants could be used as promising components both in enzyme modification and media engineering for attaining the desired goals in biocatalytic reactions.

  20. Gemini Planet Imager observational calibrations I: Overview of the GPI data reduction pipeline

    NASA Astrophysics Data System (ADS)

    Perrin, Marshall D.; Maire, Jérôme; Ingraham, Patrick; Savransky, Dmitry; Millar-Blanchaer, Max; Wolff, Schuyler G.; Ruffio, Jean-Baptiste; Wang, Jason J.; Draper, Zachary H.; Sadakuni, Naru; Marois, Christian; Rajan, Abhijith; Fitzgerald, Michael P.; Macintosh, Bruce; Graham, James R.; Doyon, René; Larkin, James E.; Chilcote, Jeffrey K.; Goodsell, Stephen J.; Palmer, David W.; Labrie, Kathleen; Beaulieu, Mathilde; De Rosa, Robert J.; Greenbaum, Alexandra Z.; Hartung, Markus; Hibon, Pascale; Konopacky, Quinn; Lafreniere, David; Lavigne, Jean-Francois; Marchis, Franck; Patience, Jenny; Pueyo, Laurent; Rantakyrö, Fredrik T.; Soummer, Rémi; Sivaramakrishnan, Anand; Thomas, Sandrine; Ward-Duong, Kimberly; Wiktorowicz, Sloane

    2014-07-01

    The Gemini Planet Imager (GPI) has as its science instrument an infrared integral field spectrograph/polarimeter (IFS). Integral field spectrographs are scientificially powerful but require sophisticated data reduction systems. For GPI to achieve its scientific goals of exoplanet and disk characterization, IFS data must be reconstructed into high quality astrometrically and photometrically accurate datacubes in both spectral and polarization modes, via flexible software that is usable by the broad Gemini community. The data reduction pipeline developed by the GPI instrument team to meet these needs is now publicly available following GPI's commissioning. This paper, the first of a series, provides a broad overview of GPI data reduction, summarizes key steps, and presents the overall software framework and implementation. Subsequent papers describe in more detail the algorithms necessary for calibrating GPI data. The GPI data reduction pipeline is open source, available from planetimager.org, and will continue to be enhanced throughout the life of the instrument. It implements an extensive suite of task primitives that can be assembled into reduction recipes to produce calibrated datasets ready for scientific analysis. Angular, spectral, and polarimetric differential imaging are supported. Graphical tools automate the production and editing of recipes, an integrated calibration database manages reference files, and an interactive data viewer customized for high contrast imaging allows for exploration and manipulation of data.

  1. Performance of the integral field spectrograph for the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Chilcote, Jeffrey K.; Larkin, James E.; Maire, Jérôme; Perrin, Marshall D.; Fitzgerald, Michael P.; Doyon, René; Thibault, Simon; Bauman, Brian; Macintosh, Bruce A.; Graham, James R.; Saddlemyer, Les

    2012-09-01

    We present performance results, from in-lab testing, of the Integral Field Spectrograph (IFS) for the Gemini Planet Imager (GPI). GPI is a facility class instrument for the Gemini Observatory with the primary goal of directly detecting young Jovian planets. The GPI IFS is based on concepts from the OSIRIS instrument at Keck and utilizes an infrared transmissive lenslet array to sample a rectangular 2.8 x 2.8 arcsecond field of view. The IFS provides low-resolution spectra across five bands between 1 and 2.5μm. Alternatively, the dispersing element can be replaced with a Wollaston prism to provide broadband polarimetry across the same five filter bands. The IFS construction was based at the University of California, Los Angeles in collaboration with the Université de Montr eal, Immervision and Lawrence Livermore National Laboratory. During its construction, we encountered an unusual noise source from microphonic pickup by the Hawaii-2RG detector. We describe this noise and how we eliminated it through vibration isolation. The IFS has passed its preship review and was shipped to University of California, Santa Cruz at the end of 2011 for integration with the remaining sub-systems of GPI. The IFS has been integrated with the rest of GPI and is delivering high quality spectral datacubes of GPI's coronagraphic field.

  2. Gemini J-band observations of RX J0806.4-4123

    NASA Astrophysics Data System (ADS)

    Posselt, B.; Luhman, K. L.

    2016-07-01

    The detection of near-infrared (NIR) excess at the position of a star can indicate either a substellar companion or a disk around the respective star. In this work we probed whether a 2.5σ H-band flux enhancement at the position of the isolated neutron star RX J0806.4-4123 can be confirmed at another NIR wavelength. We observed RX J0806.4-4123 in the J-band with Gemini South equipped with FLAMINGOS-2. There was no significant detection of a J-band source at the neutron star position. However, similarly to the H-band we found a very faint (1.4σ) flux enhancement with a nominal magnitude of J=24.8 ± 0.5. The overall NIR-detection significance is 3.1σ. If real, this emission is too bright to come from the neutron star alone. Deeper near-infrared observations are necessary to confirm or refute the potential NIR excess. The confirmation of such NIR excess could imply that there is a substellar companion or a disk around RX J0806.4-4123. Based on observations obtained at the Gemini Observatory (Program ID: GS-2014B-Q-60) and ESO Paranal Observatory (Program ID: 74.C-0596)

  3. GeMini: The Next-Generation Mechanically-Cooled Germanium Spectrometer

    SciTech Connect

    Burks, M

    2008-11-12

    The next-generation mechanically-cooled germanium spectrometer has been developed. GeMini (MINIature GErmanium spectrometer) has been designed to bring high-resolution gamma-ray spectroscopy to a range of demanding field environments. Intended applications include short-notice inspections, border patrol, port monitoring and emergency response, where positive nuclide identification of radioactive materials is required but power and liquid cryogen are not easily available. GeMini weighs 2.75 kg for the basic instrument and 4.5 kg for the full instrument including user interface and ruggedized hermetic packaging. It is very low power allowing it to operate for 10 hours on a single set of rechargeable batteries. This instrument employs technology adapted from the gamma-ray spectrometer currently flying on NASA's Mercury MESSENGER spacecraft. Specifically, infrared shielding techniques allow for a vast reduction of thermal load. This in turn allows for a smaller, lighter-weight design, well-suited for a hand-held instrument. Three working prototypes have been built and tested in the lab. The measured energy resolution is 3 keV fwhm at 662 keV gamma-rays. This paper will focus on the design and performance of the instrument.

  4. Binding behaviors of p-sulfonatocalix[4]arene with gemini guests.

    PubMed

    Zhao, Hong-Xia; Guo, Dong-Sheng; Liu, Yu

    2013-02-14

    A dozen of homoditopic cations, possessing different spacer lengths and rigidities, as well as sizes, shapes, and charges of terminal groups, were synthesized as candidate gemini guests for the complexation of p-sulfonatocalix[4]arenes (SC4A). The 12 gemini guests are divided into five species according to the different terminal groups: imidazolium (G1-G3), pyridinium (G4-G6), quinolinium (G7), viologen (G8-G11), and 1,4-diazabicyclo[2.2.2]octane (DBO, G12). Their binding structures and stoichiometries with SC4A were examined by NMR spectroscopy, which is helpful to construct diverse highly ordered assemblies. The obtained results show that the length of the linkers, as well as the charge numbers on the end groups have a pronounced effect on the binding stoichiometry, whereas the size and shape of the terminal groups have no significant influence. Furthermore, both the stability constants and thermodynamic parameters of SC4A with the terminal subunits were determined by the isothermal titration calorimetry experiments, which are valuable to understand the binding behavior, giving quantitatively deep insight.

  5. Acquisition and guiding unit for Gemini 8-m telescopes: a progress report

    NASA Astrophysics Data System (ADS)

    Heilemann, Wolfgang; Naumann, Helgard

    1998-07-01

    An international partnership of the USA, UK, Canada, Chile, Argentina and Brazil are projecting two high performance 8- meter Aperture Optical/Infrared Telescopes to be commissioned between the years 1998 and 2000 at Mauna Kea, Hawaii, and Cerro Pachon, Chile. The aim is to exploit the best natural observing conditions to undertake a broad range of astronomical research programs within the national communities of other countries. Zeiss was awarded two mayor contracts within this project, to design, manufacture and test the secondary mirrors and the Gemini Acquisition and Guiding system (GAG) for the 8m telescopes. The current paper refers to the GAG. The Gemini Acquisition and Guiding Unit are complex integrated systems, including optics, mechanical assemblies, detectors and control and signal processing software. The project is to be accomplished under subcontract and in cooperation with the Royal Greenwich Observatory in the United Kingdom. We briefly review the technological and astronomical background of the project and the technical specification of the GAG. The paper describes the design of the Acquisition and Guidance Unit, highlights some design criteria and discusses the expected performance. A report about the actual status of work is given.

  6. Synthesis and properties of a lacquer wax-based quarternary ammonium gemini surfactant.

    PubMed

    Chen, Hongxia; Wang, Chengzhang; Ye, Jianzhong; Zhou, Hao; Lu, Li; Yang, Zhibing

    2014-03-24

    Lacquer wax is an important fatty resource obtained from the mesocarp of the berries of Toxicodendron vernicifluum. In order to expand the applications of lacquer wax, we hydrolyzed it after establishing the best conditions for the acid-catalyzed hydrolysis using a Box-Behnken design. Then we synthesized a quarternary ammonium gemini surfactant by a three-step reaction. The surface properties of an aqueous solution of the final product were investigated. The optimum conditions were 9% catalyst, 100 °C of reaction temperature and 14 h of reaction time, while the maximum free fatty acids (FFA)% was 99.67%. From the gas chromatography, the main fatty acids of the lacquer wax were palmitic, oleic and octadecanoic acid. The lacquer wax gemini surfactant was synthesized, and its structure was confirmed by IR and NMR. The experiments showed that the critical micelle concentration (CMC) is 5 × 10⁻⁴ mol·L⁻¹, the surface tension is 33.6 mN·m⁻¹. When the content of surfactant was 0.1%, the separation time of 5 mL water was 10 min.

  7. The AAO's Gemini High-Resolution Optical SpecTrograph (GHOST) concept

    NASA Astrophysics Data System (ADS)

    Ireland, Michael J.; Barnes, Stuart; Cochrane, David; Colless, Matthew; Connor, Peter; Horton, Anthony; Gibson, Steve; Lawrence, Jon; Martell, Sarah; McGregor, Peter; Nicolle, Tom; Nield, Kathryn; Orr, David; Robertson, J. G.; Ryder, Stuart; Sheinis, Andrew; Smith, Greg; Staszak, Nick; Tims, Julia; Xavier, Pascal; Young, Peter; Zheng, Jessica

    2012-09-01

    The Gemini High-Resolution Optical SpecTrograph (GHOST) will fill an important gap in the current suite of Gemini instruments. We will describe the Australian Astronomical Observatory (AAO)-led concept for GHOST, which consists of a multi-object, compact, high-efficiency, fixed-format, fiber-fed design. The spectrograph itself is a four-arm variant of the asymmetric white-pupil echelle Kiwispec spectrograph, Kiwisped, produced by Industrial Research Ltd. This spectrograph has an R4 grating and a 100mm pupil, and separate cross-disperser and camera optics for each of the four arms, carefully optimized for their respective wavelength ranges. We feed this spectrograph with a miniature lensletbased IFU that sub-samples the seeing disk of a single object into 7 hexagonal sub-images, reformatting this into a slit with a second set of double microlenses at the spectrograph entrance with relatively little loss due to focal-ratio degradation. This reformatting enables high spectral resolution from a compact design that fits well within the relatively tight GHOST budget. We will describe our baseline 2-object R~50,000 design with full wavelength coverage from the ultraviolet to the silicon cutoff, as well as the high-resolution single-object R~75,000 mode.

  8. Gemini planet imager observational calibrations IV: wavelength calibration and flexure correction for the integral field spectograph

    NASA Astrophysics Data System (ADS)

    Wolff, Schuyler G.; Perrin, Marshall D.; Maire, Jérôme; Ingraham, Patrick J.; Rantakyrö, Fredrik T.; Hibon, Pascale

    2014-08-01

    We present the wavelength calibration for the lenslet-based Integral Field Spectrograph (IFS) that serves as the science instrument for the Gemini Planet Imager (GPI). The GPI IFS features a 2.7" x 2.7" field of view and a 190 x 190 lenslet array (14.3 mas/lenslet) operating in Y, J, H, and K bands with spectral resolving power ranging from R ~ 35 to 78. Due to variations across the field of view, a unique wavelength solution is determined for each lenslet characterized by a two-dimensional position, the spectral dispersion, and the rotation of the spectrum with respect to the detector axes. The four free parameters are fit using a constrained Levenberg-Marquardt least-squares minimization algorithm, which compares an individual lenslet's arc lamp spectrum to a simulated arc lamp spectrum. This method enables measurement of spectral positions to better than 1/10th of a pixel on the GPI IFS detector using Gemini's facility calibration lamp unit GCAL, improving spectral extraction accuracy compared to earlier approaches. Using such wavelength calibrations we have measured how internal flexure of the spectrograph with changing zenith angle shifts spectra on the detector. We describe the methods used to compensate for these shifts when assembling datacubes from on-sky observations using GPI.

  9. Active compensation of flexure on the High-Resolution Optical Spectrograph for Gemini

    NASA Astrophysics Data System (ADS)

    D'Arrigo, P.; Diego, Francisco; Walker, David D.

    1997-03-01

    Gravity-induced flexure has been a long-standing challenge in Cassegrain spectrographs at 4-meter class telescopes; it is the more so at the scale of 8-meter telescopes. This is of particular concern for the Gemini high resolution optical spectrograph, which will be Cassegrain-mounted for its routine mode of operation. In this paper we address the general flexure problem, and how to solve it with the use of active optics. We also present the results of an experimental active flexure compensation system for the ISIS (intermediate- dispersion spectroscopic and imaging system) spectrograph on the 4.2 m William Herschel Telescope (WHT). This instrument, called ISAAC (ISIS spectrograph automatic active collimator), is based on the concept of active correction, where spectrum drifts, due to the spectrograph flexing under the effect of gravity, are compensated by the movement of an active optical element (in this case a fine steering tip-tilt collimator mirror). The experiment showed that active compensation can reduce flexure down to less than 3 micrometer over four hours of telescope motions, dramatically improving the spectrograph performance. The results of the experiment are used to discuss a flexure compensation system for the high resolution optical spectrograph (HROS) for the 8 m Gemini telescope.

  10. The Ages, Metallicities, and Alpha Element Enhancements of Globular Clusters in the Elliptical NGC 5128: A Homogeneous Spectroscopic Study with Gemini/Gemini Multi-Object Spectrograph

    NASA Astrophysics Data System (ADS)

    Woodley, Kristin A.; Harris, William E.; Puzia, Thomas H.; Gómez, Matías; Harris, Gretchen L. H.; Geisler, Doug

    2010-01-01

    We present new integrated light spectroscopy of globular clusters (GCs) in NGC 5128, a nearby giant elliptical galaxy less than 4 Mpc away, in order to measure radial velocities and derive ages, metallicities, and alpha-element abundance ratios. Using the Gemini South 8 meter telescope with the instrument Gemini Multi-Object Spectrograph, we obtained spectroscopy in the range of ~3400-5700 Å for 72 GCs with a signal-to-noise ratio greater than 30 Å-1 and we have also discovered 35 new GCs within NGC 5128 from our radial velocity measurements. We measured and compared the Lick indices from Hδ A through Fe5406 with the single stellar population models of Thomas et al. in order to derive age, metallicity, and [α/Fe] values. We also measure Lick indices for 41 Milky Way GCs from Puzia et al. and Schiavon et al. with the same methodology for direct comparison. Our results show that 68% of the NGC 5128 GCs have old ages (>8 Gyr), 14% have intermediate ages (5-8 Gyr), and 18% have young ages (<5 Gyr). However, when we look at the metallicity of the GCs as a function of age, we find 92% of metal-poor GCs and 56% of metal-rich GCs in NGC 5128 have ages >8 Gyr, indicating that the majority of both metallicity subpopulations of GCs formed earlier, with a significant population of young and metal-rich GCs forming later. Our metallicity distribution function generated directly from spectroscopic Lick indices is clearly bimodal, as is the color distribution of the same set of GCs. Thus, the metallicity bimodality is real and not an artifact of the color to metallicity conversion. However, the metallicity distribution function obtained from comparison with the single stellar population models is consistent with a unimodal, bimodal, or multimodal shape. The [α/Fe] values are supersolar with a mean value of 0.14 ± 0.04, indicating a fast formation timescale. However, the GCs in NGC 5128 are not as [α/Fe] enhanced as the Milky Way GCs also examined in this study. Our measured

  11. Methyl bromide fumigation of packed table grapes: Effect of shipping box on gas concentrations and phytotoxicity

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Current methyl bromide schedules for table grapes to control mealybugs are approved for fruit packed in Toyon Kraft Veneer (TKV) boxes. The question arose concerning equivalence of exposure to methyl bromide if an Extruded Polystyrene (EPS) box was used in lieu of the TKV box for table grapes being ...

  12. 76 FR 7200 - Methyl Bromide; Notice of Receipt of Requests To Voluntarily Amend Registrations To Terminate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-09

    ... Certain Soil Uses AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In accordance... bromide product registrations to terminate or delete one or more soil uses. The requests would delete all methyl bromide soil uses that do not meet the definition of a ``critical use,'' a...

  13. Acrolein as Potential Alternative to Methyl Bromide in California-Grown Calla Lilies

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Cut flower and ornamental bulb industries rely heavily on a methyl bromide/chloropicrin (MB/Pic) mixture as a key pest management tool. The loss of methyl bromide (MB) will seriously affect the cut flower and bulb industry, and in the future, will require growers to use alternative fumigants. Theref...

  14. Enthalpies of complex formation of boron and aluminum bromides with organic bases of high donor power

    SciTech Connect

    Grigor-ev, A.A.; Kondrat'ev, Y.V.; Suvorov, A.V.

    1986-11-20

    By the calorimetric method enthalpies of complex formation were determined for boron and aluminum bromides with piperidine and hexamethylphosphoric triamide in benzene solutions and for boron bromide with pyridine in dichloroethane, and also enthalpies of solution were determined for BBr/sub 3/ and the adducts AlBr/sub 3/ x PPy and BBr/sub 2/ x Py in benzene and pyridine.

  15. Floriculture Production with Iodomethane, 1, 3-dichloropropene and Chloropicrin as an Alternatie to Methyl Bromide

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Cut flower growers in California have routinely used methyl bromide and chloropicrin soil fumigation to control soilborne pathogens and weeds. Because of the ban on methyl bromide production and import, alternative treatments are required. Three field trials were established to test alternative trea...

  16. Destruction of methyl bromide sorbed to activated carbon by thiosulfate and electrolysis

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Methyl bromide is widely used as a fumigant for post-harvest and quarantine uses at port facilities due to the low treatment times required, but it is vented to the atmosphere after its use. Due to the potential contributions of methyl bromide to stratospheric ozone depletion, technologies for the c...

  17. Perfluorooctyl bromide dispersions in aqueous media for biomedical applications.

    PubMed

    Habif, S S; Normand, P E; Oleksiak, C B; Rosano, H L

    1992-01-01

    In studying perfluorooctyl bromide (PFOB) dispersions in aqueous media, we have used two types of surfactant: egg yolk phospholipids (EYP) and polyglycerol esters (PGE). Our interest in these dispersions arises from their potential biomedical applications as imaging solutions and oxygen-carrying solutions (i.e., blood substitutes). For EYP systems, we have identified the dispersion structure as consisting of (a) PFOB droplets (250-nm diameter) stabilized by a phospholipid monolayer adsorbed irreversibly at the o/w interface and (b) small empty phospholipid vesicles. With both surfactants commercial preparations yielded stable systems, while purified samples, being non-dispersible, could not be made to act as emulsifiers. In both cases, minor components in the commercial surfactant were found to be necessary for the formation of a stable dispersion, enabling the transport of the pure surfactant to the PFOB/water interface.

  18. Tiotropium Bromide in Chronic Obstructive Pulmonary Disease and Bronchial Asthma

    PubMed Central

    Alvarado-Gonzalez, Alcibey; Arce, Isabel

    2015-01-01

    Inhaled bronchodilators are the mainstay of pharmacological treatment for stable chronic obstructive pulmonary disease (COPD), including β2-agonists and muscarinic antagonists. Tiotropium bromide, a long-acting antimuscarinic bronchodilator (LAMA), is a treatment choice for moderate-to-severe COPD; its efficacy and safety have been demonstrated in recent trials. Studies also point to a beneficial role of tiotropium in the treatment of difficult-to-control asthma and a potential function in the asthma-COPD overlap syndrome (ACOS). Combination of different bronchodilator molecules and addition of inhaled corticosteroids are viable therapeutic alternatives. A condensation of the latest trials and the rationale behind these therapies will be presented in this article. PMID:26491494

  19. Location of Bromide Ions in Tetragonal Lysozyme Crystals

    NASA Technical Reports Server (NTRS)

    Lim, Kap; Nadarajah, Arunan; Forsythe, Elizabeth L.; Pusey, Marc L.

    1998-01-01

    Anions have been shown to play a dominant role in the crystallization of chicken egg white lysozyme from salt solutions. Previous studies employing X-ray crystallography had found one chloride ion binding site in the tetragonal crystal form of the protein and four nitrate ion binding sites in the monoclinic form. In this study the anion positions in the tetragonal form were determined from the difference Fourier map obtained from lysozyme crystal grown in bromide and chloride solutions. Five possible anion binding sites were found in this manner. Some of these sites were in pockets containing basic residues while others were near neutral, but polar, residues. The sole chloride ion binding site found in previous studies was confirmed, while four of these sites corresponded to four binding sites found for nitrate ions in monoclinic crystals. The study suggests that most of the anion binding sites in lysozyme remain unchanged, even when different anions and different crystal forms of lysozyme are employed.

  20. Unveiling Residual Molecular Binding in Triply Charged Hydrogen Bromide

    SciTech Connect

    Penent, F.; Lablanquie, P.; Palaudoux, J.; Gamblin, G.; Carniato, S.; Andric, L.; Hikosaka, Y.; Ito, K.

    2011-03-11

    We present an experimental and theoretical study of triply charged hydrogen bromide ions formed by photoionization of the inner 3d shell of Br. The experimental results, obtained by detecting the 3d photoelectron in coincidence with the two subsequent Auger electrons, are analyzed using calculated potential energy curves of HBr{sup 3+}. The competition between the short-range chemical binding potential and the Coulomb repulsion in the dissociative process is shown. Two different mechanisms are observed for double Auger decay: one, a direct process with simultaneous ejection of two Auger electrons to final HBr{sup 3+} ionic states and the other, a cascade process involving double Auger decay characterized by the autoionization of Br*{sup +} ion subsequent to the HBr{sup 2+} fragmentation.

  1. Error Evaluation of Methyl Bromide Aerodynamic Flux Measurements

    USGS Publications Warehouse

    Majewski, M.S.

    1997-01-01

    Methyl bromide volatilization fluxes were calculated for a tarped and a nontarped field using 2 and 4 hour sampling periods. These field measurements were averaged in 8, 12, and 24 hour increments to simulate longer sampling periods. The daily flux profiles were progressively smoothed and the cumulative volatility losses increased by 20 to 30% with each longer sampling period. Error associated with the original flux measurements was determined from linear regressions of measured wind speed and air concentration as a function of height, and averaged approximately 50%. The high errors resulted from long application times, which resulted in a nonuniform source strength; and variable tarp permeability, which is influenced by temperature, moisture, and thickness. The increase in cumulative volatilization losses that resulted from longer sampling periods were within the experimental error of the flux determination method.

  2. Perfluorooctyl bromide dispersions in aqueous media for biomedical applications.

    PubMed

    Habif, S S; Normand, P E; Oleksiak, C B; Rosano, H L

    1992-01-01

    In studying perfluorooctyl bromide (PFOB) dispersions in aqueous media, we have used two types of surfactant: egg yolk phospholipids (EYP) and polyglycerol esters (PGE). Our interest in these dispersions arises from their potential biomedical applications as imaging solutions and oxygen-carrying solutions (i.e., blood substitutes). For EYP systems, we have identified the dispersion structure as consisting of (a) PFOB droplets (250-nm diameter) stabilized by a phospholipid monolayer adsorbed irreversibly at the o/w interface and (b) small empty phospholipid vesicles. With both surfactants commercial preparations yielded stable systems, while purified samples, being non-dispersible, could not be made to act as emulsifiers. In both cases, minor components in the commercial surfactant were found to be necessary for the formation of a stable dispersion, enabling the transport of the pure surfactant to the PFOB/water interface. PMID:1369226

  3. N-(2-Bromo­benz­yl)cinchoninium bromide

    PubMed Central

    Skórska-Stania, Agnieszka; Jezierska-Zięba, Magdalena; Kąkol, Barbara; Fedoryński, Michał; Oleksyn, Barbara J.

    2012-01-01

    The title compound {systematic name: 1-(2-bromo­benz­yl)-5-ethenyl-2-[hy­droxy(quinolin-4-yl)meth­yl]-1-aza­bicyclo­[2.2.2]octan-1-ium bromide}, C26H28BrN2O+·Br−, is a chiral quater­nary ammonium salt of one of the Cinchona alkaloids. The planes of the quinoline and of the bromo­benzyl substituent are inclined to one another by 9.11 (9)°. A weak intra­molecular C—H⋯O hydrogen bond occurs. The crystal structure features strong O—H⋯Br hydrogen bonds and weak C—H⋯Br inter­actions. PMID:22969676

  4. Combined intranasal ipratropium bromide and oxymetazoline in experimental rhinovirus infection.

    PubMed

    Pitkäranta, A; Wecker, M T; Korts, D C; Hayden, F G

    1998-01-01

    The topical anticholinergic ipratropium bromide and topical decongestant oxymetazoline were tested to determine whether oxymetazoline alone and the combination were well tolerated and reduced rhinorrhea and middle ear pressure abnormalities during experimental rhinovirus infection. The study was double-bind, placebo-controlled, and double dummy in design. Healthy volunteers (n = 109) with low serum neutralizing antibody titer (< or = 1:2) were. Treatments inoculated with rhinovirus (type 39 or Hank's strain) and randomized to treatment with ipra-tropium bromide 0.06% two sprays per nostril (84 micrograms per treatment) and oxymetazoline 0.05% two sprays per nostril, oxymetazoline alone, or placebo. Treatments were self administered twice daily for 5 days beginning 1 day after rhinovirus inoculation. The overall infection rate was 83% and of those infected, 88% felt that they had a cold. During the 3-hour period after dosing, the increase in nasal discharge was significantly lower in the combined ipratropium and oxymetazoline (0.13 +/- 0.17 gm/3 hr, mean +/- SE) than after oxymetazoline alone (0.60 +/- 0.18 gm/3 hr) or vehicle (0.73 +/- 0.18 gm/3 hr). Over the 5-day observation period, total daily nasal discharge also tended to be lower in the ipratropium plus oxymetazoline group (3.67 +/- 0.70 gm/24 hr, mean +/- SE) compared to oxymetazoline (5.61 +/- 0.73: 35% reduction) or the vehicle (5.04 +/- 0.73; 27% reduction) recipients, but the differences were not statistically significant. Subjective assessments of rhinorrhea indicated that the severity of rhinorrhea was significantly better among patients receiving oxymetazoline alone or with ipratropium compared to the vehicle. No significant difference in the cumulative frequencies of middle ear pressure abnormalities (27-31%) were found among the treatment groups. Oxymetazoline does not consistently stimulate or decrease nasal mucus production, and ipratropium added to oxymetazoline is well tolerated and reduces

  5. Comparative mobility of sulfonamides and bromide tracer in three soils

    USGS Publications Warehouse

    Kurwadkar, S.T.; Adams, C.D.; Meyer, M.T.; Kolpin, D.W.

    2011-01-01

    In animal agriculture, sulfonamides are one of the routinely used groups of antimicrobials for therapeutic and sub-therapeutic purposes. It is observed that, the animals when administered the antimicrobials, often do not completely metabolize them; and excrete the partially metabolized forms into the environment. Due to the continued use of antimicrobials and disposal of untreated waste, widespread occurrence of partially metabolized antimicrobials in aquatic and terrestrial environments has been reported in various scientific journals. In this research, the mobility of two sulfonamides - sulfamethazine (SMN), sulfathiazole (STZ) and a conservative bromide tracer was investigated in three soils collected from regions in the United States with large number of concentrated animal-feed operations. Results of a series of column studies indicate that the mobility of these two sulfonamides was dependent on pH, soil charge density, and contact time. At low pH and high charge density, substantial retention of sulfonamides was observed in all three soils investigated, due to the increased fraction of cationic and neutral forms of the sulfonamides. Conversely, enhanced mobility was observed at high pH, where the sulfonamides are predominantly in the anionic form. The results indicate that when both SMN and STZ are predominantly in anionic forms, their mobility approximates the mobility of a conservative bromide tracer. This observation is consistent for the mobility of both SMN and STZ individually, and also in the presence of several other antimicrobials in all three soils investigated. Higher contact time indicates lower mobility due to increased interaction with soil material. ?? 2011.

  6. Exploración con GEMINI-GMOS del sistema de cúmulos globulares de NGC 5044

    NASA Astrophysics Data System (ADS)

    Faifer, F. R.; Cellone, S. A.; Smith Castelli, A. V.; Bassino, L. P.; Forte, J. C.

    We present preliminary results of the first photometric study of the globular cluster system associated to the elliptical galaxy NGC 5044, the dominant object in the homonymous group. These results are based on data recently (semester 2009A) obtained with the Multi Object Spectrograph GMOS at the Gemini South telescope. FULL TEXT IN SPANISH

  7. Experimenting with Synthesis and Analysis of Cationic Gemini Surfactants in a Second-Semester General Chemistry Laboratory

    ERIC Educational Resources Information Center

    Anzovino, Mary E.; Greenberg, Andrew E.; Moore, John W.

    2015-01-01

    A laboratory experiment is described in which students synthesize a variety of cationic gemini surfactants and analyze their efficacy as fabric softeners. Students perform a simple organic synthesis reaction and two analytical tests (one qualitative and one quantitative), and use the class data to assess the synthesized products. The experiment…

  8. Interactions of bovine serum albumin with cationic imidazolium and quaternary ammonium gemini surfactants: effects of surfactant architecture.

    PubMed

    Zhou, Ting; Ao, Mingqi; Xu, Guiying; Liu, Teng; Zhang, Juan

    2013-01-01

    The interactions of BSA with a series of cationic imidazolium gemini surfactants ([C(n)-s-C(n)im]Br(2), n=10, 12, 14, s=2, 4, 6), quaternary ammonium surfactants (C(12)C(2)C(12)), and their corresponding monomers ([C(12)mim]Br and DTAB) are investigated by fluorescence using pyrene as a molecular probe, synchronous fluorescence, circular dichroism (CD), and UV-visible absorption spectra. These surfactants are used to elucidate the effects of surfactant hydrophilic head group, spacer length, and hydrophobic chain length on the conformation of BSA. The results of fluorescence spectra and CD show that the imidazolium gemini surfactants with shorter spacers or with longer hydrophobic chains have a larger effect on BSA unfolding, and the imidazolium gemini surfactant interacts with BSA more strongly than its corresponding monomer and the quaternary ammonium gemini surfactant. These conclusions have been confirmed by the binding constants (K(a)) and binding sites (n) for the BSA/surfactant system. Stern-Volmer quenching constants K(SV) of cationic surfactants binding to BSA are obtained, indicating that the probable quenching mechanism is initiated by ground-state complex formation rather than by dynamic collision. Moreover, the synchronous fluorescence spectra show that the surfactants mainly interact with tryptophan residues of BSA.

  9. 78 FR 40541 - GDT Tek, Inc., Gemini Explorations, Inc., Genetic Vectors, Inc., and Global Gate Property Corp...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION GDT Tek, Inc., Gemini Explorations, Inc., Genetic Vectors, Inc., and Global Gate Property Corp... accurate information concerning the securities of Genetic Vectors, Inc. because it has not filed...

  10. The influence of novel gemini surfactants containing cycloalkyl side-chains on the structural phases of DNA in solution.

    PubMed

    Pietralik, Zuzanna; Kumita, Janet R; Dobson, Christopher M; Kozak, Maciej

    2015-07-01

    Very important to gene therapy is the delivery system of the nucleic acids (called a vector), which will enhance the efficiency of the transport of new DNA into cells whilst protecting against damage. A promising alternative to the currently used viral vectors are the systems based on amphiphilic compounds - lipoplexes. Among them, gemini surfactants, which consist of two hydrophobic chains and two cationic heads connected by a linker - spacer group, appear to be promising candidates. The subject of this study involves two gemini surfactants, alkoxy derivatives of bis-imidazolium quaternary salts, differing in the length of their spacer groups and how they interact with two types of salmon sperm DNA (low and high molecular weight (MW)) or plasmid DNA (pDNA). The mixtures of gemini surfactants with nucleic acids of differing p/n ratios (positive-to-negative charge ratio) were characterised by small angle X-ray scattering (SAXS) of synchrotron radiation, dynamic light scattering (DLS), circular dichroism (CD) spectroscopy, atomic force microscopy (AFM), transmission electron microscopy (TEM) and gel electrophoresis techniques. This analysis allows for the selection of the most suitable and promising candidates for non-viral vectors in gene therapy, determination of the conditions needed to form stable complexes, identification of conformational changes in the DNA molecules upon interactions with gemini surfactants and in some cases, determination of the structures formed in these lipoplexes.

  11. Action of pinaverium bromide, a calcium-antagonist, on gastrointestinal motility disorders.

    PubMed

    Christen, M O

    1990-01-01

    1. The evidence reviewed here indicates that pinaverium bromide (Dicetel) relaxes gastrointestinal (GI) structures primarily by inhibiting Ca2+ influx through potential-dependent channels of surface membranes of smooth muscle cells. 2. The in vivo selectivity of pinaverium bromide for the GI tract appears to be due mainly to its pharmacokinetic properties. Because of its low absorption (typical for quaternary ammonium compounds) and marked hepatobiliary excretion, most of the orally-administered dose of pinaverium bromide remains in the GI tract. 3. Orally-administered pinaverium bromide does not elicit adverse cardiovascular side-effects at doses that effectively relieve GI spasm, pain, transit disturbances and other symptoms related to motility disorders. 4. Pinaverium bromide is the only Ca2(+)-antagonist with known therapeutic efficacy in the treatment of irritable bowel syndrome and certain other functional intestinal disorders. PMID:2177709

  12. X-Ray absorption spectroscopy investigation of 1-alkyl-3-methylimidazolium bromide salts

    SciTech Connect

    D'Angelo, Paola; Zitolo, Andrea; Migliorati, Valentina; Bodo, Enrico; Caminiti, Ruggero; Aquilanti, Giuliana; Hazemann, Jean Louis; Testemale, Denis; Mancini, Giordano

    2011-08-21

    X-ray absorption spectroscopy (XAS) has been used to unveil the bromide ion local coordination structure in 1-alkyl-3-methylimidazolium bromide [C{sub n}mim]Br ionic liquids (ILs) with different alkyl chains. The XAS spectrum of 1-ethyl-3-methylimidazolium bromide has been found to be different from those of the other members of the series, from the butyl to the decyl derivatives, that have all identical XAS spectra. This result indicates that starting from 1-buthyl-3-methylimidazolium bromide the local molecular arrangement around the bromide anion is the same independently from the length of the alkyl chain, and that the imidazolium head groups in the liquid ILs with long alkyl chains assume locally the same orientation as in the [C{sub 4}mim]Br crystal. With this study we show that the XAS technique is an effective direct tool for unveiling the local structural arrangements around selected atoms in ILs.

  13. SUBARU AND GEMINI OBSERVATIONS OF SS 433: NEW CONSTRAINT ON THE MASS OF THE COMPACT OBJECT

    SciTech Connect

    Kubota, K.; Ueda, Y.; Fabrika, S.; Barsukova, E. A.; Sholukhova, O.; Medvedev, A.; Goranskij, V. P.

    2010-02-01

    We present results of optical spectroscopic observations of the mass donor star in SS 433 with Subaru and Gemini, with an aim to best constrain the mass of the compact object. Subaru/Faint Object Camera and Spectrograph observations were performed on four nights of 2007 October 6-8 and 10, covering the orbital phase of phi = 0.96 - 0.26. We first calculate the cross-correlation function (CCF) of these spectra with that of the reference star HD 9233 in the wavelength range of 4740-4840 A. This region is selected to avoid 'strong' absorption lines accompanied with contaminating emission components, which most probably originate from the surroundings of the donor star, such as the wind and gas stream. The same analysis is applied to archive data of Gemini/GMOS taken at phi = 0.84 - 0.30 by Hillwig and Gies. From the Subaru and Gemini CCF results, the amplitude of the radial velocity curve of the donor star is determined to be 58.3 +- 3.8 km s{sup -1} with a systemic velocity of 59.2 +- 2.5 km s{sup -1}. Together with the radial velocity curve of the compact object, we derive the mass of the donor star and compact object to be M{sub O} = 12.4 +- 1.9 M{sub sun} and M{sub X} = 4.3 +- 0.6 M{sub sun}, respectively. We conclude, however, that these values should be taken as upper limits. From the analysis of the averaged absorption line profiles of strong lines (mostly ions) and weak lines (mostly neutrals) observed with Subaru, we find evidence for heating effects from the compact object. Using a simple model, we find that the true radial velocity amplitude of the donor star could be as low as 40 +- 5 km s{sup -1} in order to produce the observed absorption-line profiles. Taking into account the heating of the donor star may lower the derived masses to M{sub O} = 10.4{sup +2.3}{sub -1.9} M{sub sun} and M{sub X} = 2.5{sup +0.7}{sub -0.6} M{sub sun}. Our final constraint, 1.9 M{sub sun} <=M{sub X}<= 4.9 M{sub sun}, indicates that the compact object in SS 433 is most likely a

  14. The Gemini NICI planet-finding campaign: The offset ring of HR 4796 A

    NASA Astrophysics Data System (ADS)

    Wahhaj, Zahed; Liu, Michael C.; Biller, Beth A.; Nielsen, Eric L.; Hayward, Thomas L.; Kuchner, Marc; Close, Laird M.; Chun, Mark; Ftaclas, Christ; Toomey, Douglas W.

    2014-07-01

    We present J,H, CH4 short (1.578 μm), CH4 long (1.652 μm) and Ks-band images of the dust ring around the 10 Myr old star HR 4796 A obtained using the Near Infrared Coronagraphic Imager (NICI) on the Gemini-South 8.1 m Telescope. Our images clearly show for the first time the position of the star relative to its circumstellar ring thanks to NICI's translucent focal plane occulting mask. We employ a Bayesian Markov chain Monte Carlo method to constrain the offset vector between the two. The resulting probability distribution shows that the ring center is offset from the star by 16.7 ± 1.3 milliarcseconds along a position angle of 26 ± 3°, along the PA of the ring, 26.47 ± 0.04°. We find that the size of this offset is not large enough to explain the brightness asymmetry of the ring. The ring is measured to have mostly red reflectivity across the JHKs filters, which seems to indicate micron-sized grains. Just like Neptune's 3:2 and 2:1 mean-motion resonances delineate the inner and outer edges of the classical Kuiper belt, we find that the radial extent of the HR 4796 A and the Fomalhaut rings could correspond to the 3:2 and 2:1 mean-motion resonances of hypothetical planets at 54.7 AU and 97.7 AU in the two systems, respectively. A planet orbiting HR 4796 A at 54.7 AU would have to be less massive than 1.6 MJup so as not to widen the ring too much by stirring. Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the Science and Technology Facilities Council (United Kingdom), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência e Tecnologia (Brazil) and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina).Tables 5 and 6 are available in electronic form at

  15. Interaction of a green ester-bonded gemini surfactant with xanthine oxidase: Biophysical perspective.

    PubMed

    Akram, Mohd; Bhat, Imtiyaz Ahmad; Kabir-ud-Din

    2015-01-01

    A multi technique approach was utilized to explore the interaction between a novel green gemini surfactant, ethane-1,2-diyl bis(N,N-dimethyl-N-tetradecylammoniumacetoxy) dichloride (14-E2-14), with bovine milk xanthine oxidase (XO). Tensiometric, spectroscopic, microscopic and molecular modeling results demonstrate significant interaction and structural change of native xanthine oxidase upon 14-E2-14 combination. The results obtained in this study may be beneficial for scientists to calibrate conformation of the enzyme by novel biodegradable/green microstructures; consequently, it would likely add new impetus in understanding the treatment modes of various diseases like gout, hyperuricemia, liver and brain necrosis. Moreover, the 14-E2-14-XO interaction assists to unfurl new routes in the designing/selection of green-surfactant-protein mixtures widely used in food processing, cosmetics, and pharmaceutical industries.

  16. Interaction of a green ester-bonded gemini surfactant with xanthine oxidase: Biophysical perspective.

    PubMed

    Akram, Mohd; Bhat, Imtiyaz Ahmad; Kabir-ud-Din

    2015-01-01

    A multi technique approach was utilized to explore the interaction between a novel green gemini surfactant, ethane-1,2-diyl bis(N,N-dimethyl-N-tetradecylammoniumacetoxy) dichloride (14-E2-14), with bovine milk xanthine oxidase (XO). Tensiometric, spectroscopic, microscopic and molecular modeling results demonstrate significant interaction and structural change of native xanthine oxidase upon 14-E2-14 combination. The results obtained in this study may be beneficial for scientists to calibrate conformation of the enzyme by novel biodegradable/green microstructures; consequently, it would likely add new impetus in understanding the treatment modes of various diseases like gout, hyperuricemia, liver and brain necrosis. Moreover, the 14-E2-14-XO interaction assists to unfurl new routes in the designing/selection of green-surfactant-protein mixtures widely used in food processing, cosmetics, and pharmaceutical industries. PMID:25849998

  17. Effect of Gemini primary mirror position relative to the lateral support on mirror figure

    NASA Astrophysics Data System (ADS)

    Cho, Myung K.; Stepp, Larry M.

    2000-07-01

    The Gemini primary mirror support incorporates a system of hydraulic whiffletrees to carry the mirror weight and define its position. The six orthogonal kinematic degrees of freedom are controlled by six hydraulic zones--three axial, two lateral, plus a transverse lateral. By varying the fluid volumes in these hydraulic zones the mirror position can be adjusted in all six degrees of freedom. Because of the finite lengths of the linkages that connect the mirror to the lateral supports, any shift in mirror position changes the amplitudes and directions of the applied forces with a resulting effect on the static balance and mirror figure. These effects have been calculated for mirror translations and rotations in all six degrees of freedom, resulting in predictions of the changes in the axial and lateral support forces and in the mirror figure. This paper describes the modeling as well as experimental verification of the results.

  18. GEMINI PLANET IMAGER SPECTROSCOPY OF THE HR 8799 PLANETS c AND d

    SciTech Connect

    Ingraham, Patrick; Macintosh, Bruce; Marley, Mark S.; Saumon, Didier; Marois, Christian; Dunn, Jennifer; Erikson, Darren; Barman, Travis; Bauman, Brian; Burrows, Adam; Chilcote, Jeffrey K.; Fitzgerald, Michael P.; De Rosa, Robert J.; Dillon, Daren; Gavel, Donald; Doyon, René; Goodsell, Stephen J.; Hartung, Markus; Hibon, Pascale; Graham, James R.; and others

    2014-10-10

    During the first-light run of the Gemini Planet Imager we obtained K-band spectra of exoplanets HR 8799 c and d. Analysis of the spectra indicates that planet d may be warmer than planet c. Comparisons to recent patchy cloud models and previously obtained observations over multiple wavelengths confirm that thick clouds combined with horizontal variation in the cloud cover generally reproduce the planets' spectral energy distributions. When combined with the 3 to 4 μm photometric data points, the observations provide strong constraints on the atmospheric methane content for both planets. The data also provide further evidence that future modeling efforts must include cloud opacity, possibly including cloud holes, disequilibrium chemistry, and super-solar metallicity.

  19. Discovery and spectroscopy of the young Jovian planet 51 Eri b with the Gemini Planet Imager

    DOE PAGES

    Macintosh, B.; Graham, J. R.; Barman, T.; De Rosa, R. J.; Konopacky, Q.; Marley, M. S.; Marois, C.; Nielsen, E. L.; Pueyo, L.; Rajan, A.; et al

    2015-10-02

    Directly detecting thermal emission from young extrasolar planets allows measurement of their atmospheric compositions and luminosities, which are influenced by their formation mechanisms. Using the Gemini Planet Imager, we discovered a planet orbiting the ~20-million-year-old star 51 Eridani at a projected separation of 13 astronomical units. Near-infrared observations show a spectrum with strong methane and water-vapor absorption. Modeling of the spectra and photometry yields a luminosity (normalized by the luminosity of the Sun) of 1.6 to 4.0 × 10–6 and an effective temperature of 600 to 750 kelvin. For this age and luminosity, “hot-start” formation models indicate a mass twicemore » that of Jupiter. As a result, this planet also has a sufficiently low luminosity to be consistent with the “cold-start” core-accretion process that may have formed Jupiter.« less

  20. Gemini Planet Imager Spectroscopy of the HR 8799 Planets c and d

    DOE PAGES

    Ingraham, Patrick; Marley, Mark S.; Saumon, Didier; Marois, Christian; Macintosh, Bruce; Barman, Travis; Bauman, Brian; Burrows, Adam; Chilcote, Jeffrey K.; De Rosa, Robert J.; et al

    2014-09-30

    During the first-light run of the Gemini Planet Imager we obtained K-band spectra of exoplanets HR 8799 c and d. Analysis of the spectra indicates that planet d may be warmer than planet c. Comparisons to recent patchy cloud models and previously obtained observations over multiple wavelengths confirm that thick clouds combined with horizontal variation in the cloud cover generally reproduce the planets’ spectral energy distributions.When combined with the 3 to 4μm photometric data points, the observations provide strong constraints on the atmospheric methane content for both planets. Lastly, the data also provide further evidence that future modeling efforts mustmore » include cloud opacity, possibly including cloud holes, disequilibrium chemistry, and super-solar metallicity.« less

  1. The Gemini secondary mirror tip/tilt system: past, present, and future

    NASA Astrophysics Data System (ADS)

    Carter, Christopher J.; Rippa, Mathew J.; Rojas, Roberto; Sheehan, Michael P.

    2008-07-01

    The Gemini Observatory is currently in the early stages of a major upgrade of the Secondary Mirror Tip/tilt Systems (M2TS). Although these systems continue to deliver good fast-steering and chopping performance at both sites, there are persistent and occasionally time-consuming issues that need to be addressed in order for them to deliver their full potential and further reduce downtime. We present an overview of the system, outline its capabilities, and review the early commissioning process and some of the issues encountered. We describe the augmentation of the original system with data logging features which made possible some critical servo tuning work that was key in delivering improved performance. The hardware and software upgrade project to date is discussed, along with a brief overview of items it intends to address.

  2. Discovery and spectroscopy of the young jovian planet 51 Eri b with the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Macintosh, B.; Graham, J. R.; Barman, T.; De Rosa, R. J.; Konopacky, Q.; Marley, M. S.; Marois, C.; Nielsen, E. L.; Pueyo, L.; Rajan, A.; Rameau, J.; Saumon, D.; Wang, J. J.; Patience, J.; Ammons, M.; Arriaga, P.; Artigau, E.; Beckwith, S.; Brewster, J.; Bruzzone, S.; Bulger, J.; Burningham, B.; Burrows, A. S.; Chen, C.; Chiang, E.; Chilcote, J. K.; Dawson, R. I.; Dong, R.; Doyon, R.; Draper, Z. H.; Duchêne, G.; Esposito, T. M.; Fabrycky, D.; Fitzgerald, M. P.; Follette, K. B.; Fortney, J. J.; Gerard, B.; Goodsell, S.; Greenbaum, A. Z.; Hibon, P.; Hinkley, S.; Cotten, T. H.; Hung, L.-W.; Ingraham, P.; Johnson-Groh, M.; Kalas, P.; Lafreniere, D.; Larkin, J. E.; Lee, J.; Line, M.; Long, D.; Maire, J.; Marchis, F.; Matthews, B. C.; Max, C. E.; Metchev, S.; Millar-Blanchaer, M. A.; Mittal, T.; Morley, C. V.; Morzinski, K. M.; Murray-Clay, R.; Oppenheimer, R.; Palmer, D. W.; Patel, R.; Perrin, M. D.; Poyneer, L. A.; Rafikov, R. R.; Rantakyrö, F. T.; Rice, E. L.; Rojo, P.; Rudy, A. R.; Ruffio, J.-B.; Ruiz, M. T.; Sadakuni, N.; Saddlemyer, L.; Salama, M.; Savransky, D.; Schneider, A. C.; Sivaramakrishnan, A.; Song, I.; Soummer, R.; Thomas, S.; Vasisht, G.; Wallace, J. K.; Ward-Duong, K.; Wiktorowicz, S. J.; Wolff, S. G.; Zuckerman, B.

    2015-10-01

    Directly detecting thermal emission from young extrasolar planets allows measurement of their atmospheric compositions and luminosities, which are influenced by their formation mechanisms. Using the Gemini Planet Imager, we discovered a planet orbiting the ~20-million-year-old star 51 Eridani at a projected separation of 13 astronomical units. Near-infrared observations show a spectrum with strong methane and water-vapor absorption. Modeling of the spectra and photometry yields a luminosity (normalized by the luminosity of the Sun) of 1.6 to 4.0 × 10-6 and an effective temperature of 600 to 750 kelvin. For this age and luminosity, “hot-start” formation models indicate a mass twice that of Jupiter. This planet also has a sufficiently low luminosity to be consistent with the “cold-start” core-accretion process that may have formed Jupiter.

  3. Discovery and spectroscopy of the young jovian planet 51 Eri b with the Gemini Planet Imager.

    PubMed

    Macintosh, B; Graham, J R; Barman, T; De Rosa, R J; Konopacky, Q; Marley, M S; Marois, C; Nielsen, E L; Pueyo, L; Rajan, A; Rameau, J; Saumon, D; Wang, J J; Patience, J; Ammons, M; Arriaga, P; Artigau, E; Beckwith, S; Brewster, J; Bruzzone, S; Bulger, J; Burningham, B; Burrows, A S; Chen, C; Chiang, E; Chilcote, J K; Dawson, R I; Dong, R; Doyon, R; Draper, Z H; Duchêne, G; Esposito, T M; Fabrycky, D; Fitzgerald, M P; Follette, K B; Fortney, J J; Gerard, B; Goodsell, S; Greenbaum, A Z; Hibon, P; Hinkley, S; Cotten, T H; Hung, L-W; Ingraham, P; Johnson-Groh, M; Kalas, P; Lafreniere, D; Larkin, J E; Lee, J; Line, M; Long, D; Maire, J; Marchis, F; Matthews, B C; Max, C E; Metchev, S; Millar-Blanchaer, M A; Mittal, T; Morley, C V; Morzinski, K M; Murray-Clay, R; Oppenheimer, R; Palmer, D W; Patel, R; Perrin, M D; Poyneer, L A; Rafikov, R R; Rantakyrö, F T; Rice, E L; Rojo, P; Rudy, A R; Ruffio, J-B; Ruiz, M T; Sadakuni, N; Saddlemyer, L; Salama, M; Savransky, D; Schneider, A C; Sivaramakrishnan, A; Song, I; Soummer, R; Thomas, S; Vasisht, G; Wallace, J K; Ward-Duong, K; Wiktorowicz, S J; Wolff, S G; Zuckerman, B

    2015-10-01

    Directly detecting thermal emission from young extrasolar planets allows measurement of their atmospheric compositions and luminosities, which are influenced by their formation mechanisms. Using the Gemini Planet Imager, we discovered a planet orbiting the ~20-million-year-old star 51 Eridani at a projected separation of 13 astronomical units. Near-infrared observations show a spectrum with strong methane and water-vapor absorption. Modeling of the spectra and photometry yields a luminosity (normalized by the luminosity of the Sun) of 1.6 to 4.0 × 10(-6) and an effective temperature of 600 to 750 kelvin. For this age and luminosity, "hot-start" formation models indicate a mass twice that of Jupiter. This planet also has a sufficiently low luminosity to be consistent with the "cold-start" core-accretion process that may have formed Jupiter. PMID:26272904

  4. Discovery and spectroscopy of the young jovian planet 51 Eri b with the Gemini Planet Imager.

    PubMed

    Macintosh, B; Graham, J R; Barman, T; De Rosa, R J; Konopacky, Q; Marley, M S; Marois, C; Nielsen, E L; Pueyo, L; Rajan, A; Rameau, J; Saumon, D; Wang, J J; Patience, J; Ammons, M; Arriaga, P; Artigau, E; Beckwith, S; Brewster, J; Bruzzone, S; Bulger, J; Burningham, B; Burrows, A S; Chen, C; Chiang, E; Chilcote, J K; Dawson, R I; Dong, R; Doyon, R; Draper, Z H; Duchêne, G; Esposito, T M; Fabrycky, D; Fitzgerald, M P; Follette, K B; Fortney, J J; Gerard, B; Goodsell, S; Greenbaum, A Z; Hibon, P; Hinkley, S; Cotten, T H; Hung, L-W; Ingraham, P; Johnson-Groh, M; Kalas, P; Lafreniere, D; Larkin, J E; Lee, J; Line, M; Long, D; Maire, J; Marchis, F; Matthews, B C; Max, C E; Metchev, S; Millar-Blanchaer, M A; Mittal, T; Morley, C V; Morzinski, K M; Murray-Clay, R; Oppenheimer, R; Palmer, D W; Patel, R; Perrin, M D; Poyneer, L A; Rafikov, R R; Rantakyrö, F T; Rice, E L; Rojo, P; Rudy, A R; Ruffio, J-B; Ruiz, M T; Sadakuni, N; Saddlemyer, L; Salama, M; Savransky, D; Schneider, A C; Sivaramakrishnan, A; Song, I; Soummer, R; Thomas, S; Vasisht, G; Wallace, J K; Ward-Duong, K; Wiktorowicz, S J; Wolff, S G; Zuckerman, B

    2015-10-01

    Directly detecting thermal emission from young extrasolar planets allows measurement of their atmospheric compositions and luminosities, which are influenced by their formation mechanisms. Using the Gemini Planet Imager, we discovered a planet orbiting the ~20-million-year-old star 51 Eridani at a projected separation of 13 astronomical units. Near-infrared observations show a spectrum with strong methane and water-vapor absorption. Modeling of the spectra and photometry yields a luminosity (normalized by the luminosity of the Sun) of 1.6 to 4.0 × 10(-6) and an effective temperature of 600 to 750 kelvin. For this age and luminosity, "hot-start" formation models indicate a mass twice that of Jupiter. This planet also has a sufficiently low luminosity to be consistent with the "cold-start" core-accretion process that may have formed Jupiter.

  5. Gemini H-band spectroscopy of the Galactic microquasar GRS 1915+105

    NASA Astrophysics Data System (ADS)

    McConnell, O.; Callanan, P.; Reynolds, M.

    2014-07-01

    Since its discovery in 1994 (Castro-Tirado 1994) GRS 1915+105 has become one of the most intensely studied of all the X-ray binaries in the Galaxy. This Galactic microquasar system is unique in that it has remained in outburst for the past 20 years: furthermore, initial measurements suggested a relatively high black hole mass of 14 ± 4 M_{⊙} (Greiner et al. 2001), outside the predicted mass range for such transients (Ozel et al. 2010). Here we present new Gemini H-band observations, and discuss the degree to which they can be used to refine the black hole mass in comparison to more recent estimates (Hurley et al 2013, Steeghs et al 2013). In addition, previous work found phase dependent emission of the CO bandheads in the K-band, and we present evidence of double peaked emission lines, indicative of ongoing mass transfer via the accretion disk.

  6. Direct observation of extrasolar planets and the development of the gemini planet imager integral field spectrograph

    NASA Astrophysics Data System (ADS)

    Chilcote, Jeffrey Kaplan

    This thesis is focused on the development and testing of a new instrument capable of finding and characterizing recently-formed Jupiter-sized planets orbiting other stars. To observe these planets, I present the design, construction and testing of the Gemini Planet Imager (GPI) Integral Field Spectrograph (IFS). GPI is a facility class instrument for the Gemini Observatory with the primary goal of directly detecting young Jovian planets. The GPI IFS utilizes an infrared transmissive lenslet array to sample a rectangular 2.7 x 2.7 arcsecond field of view and provide low-resolution spectra across five bands between 1 and 2.5 mum. The dispersing element can be replaced with a Wollaston prism to provide broadband polarimetry across the same five filter bands. The IFS construction was based at the University of California, Los Angeles in collaboration with the Universite de Montreal, Immervision and Lawrence Livermore National Laboratory. I will present performance results, from in-lab testing, of the Integral Field Spectrograph (IFS) for the Gemini Planet Imager (GPI). The IFS is a large, complex, cryogenic, optical system requiring several years of development and testing. I will present the design and integration of the mechanical and optical performance of the spectrograph optics. The IFS passed its pre-ship review in 2011 and was shipped to University of California, Santa Cruz for integration with the remaining sub-systems of GPI. The UCLA built GPI IFS was integrated with the rest of GPI and is delivering high quality spectral datacubes of GPI's coronagraphic field. Using the NIRC2 instrument located at the Keck Observatory, my collaborators and I observed the planetary companion to beta Pictoris in L' (3.5--4.1mum). Observations taken in the fall of 2009 and 2012 are used to find the location and inclination of the planet relative to the massive debris disk orbiting beta Pictoris. We find that the planet's orbit has a position angle on the sky of 211

  7. Discovery and spectroscopy of the young Jovian planet 51 Eri b with the Gemini Planet Imager

    SciTech Connect

    Macintosh, B.; Graham, J. R.; Barman, T.; De Rosa, R. J.; Konopacky, Q.; Marley, M. S.; Marois, C.; Nielsen, E. L.; Pueyo, L.; Rajan, A.; Rameau, J.; Saumon, D.; Wang, J. J.; Patience, J.; Ammons, M.; Arriaga, P.; Artigau, E.; Beckwith, S.; Brewster, J.; Bruzzone, S.; Bulger, J.; Burningham, B.; Burrows, A. S.; Chen, C.; Chiang, E.; Chilcote, J. K.; Dawson, R. I.; Dong, R.; Doyon, R.; Draper, Z. H.; Duchene, G.; Esposito, T. M.; Fabrycky, D.; Fitzgerald, M. P.; Follette, K. B.; Fortney, J. J.; Gerard, B.; Goodsell, S.; Greenbaum, A. Z.; Hibon, P.; Hinkley, S.; Cotten, T. H.; Hung, L. -W.; Ingraham, P.; Johnson-Groh, M.; Kalas, P.; Lafreniere, D.; Larkin, J. E.; Lee, J.; Line, M.; Long, D.; Maire, J.; Marchis, F.; Matthews, B. C.; Max, C. E.; Metchev, S.; Millar-Blanchaer, M. A.; Mittal, T.; Morley, C. V.; Morzinski, K. M.; Murray-Clay, R.; Oppenheimer, R.; Palmer, D. W.; Patel, R.; Perrin, M. D.; Poyneer, L. A.; Rafikov, R. R.; Rantakyro, F. T.; Rice, E. L.; Rojo, P.; Rudy, A. R.; Ruffio, J. -B.; Ruiz, M. T.; Sadakuni, N.; Saddlemyer, L.; Salama, M.; Savransky, D.; Schneider, A. C.; Sivaramakrishnan, A.; Song, I.; Soummer, R.; Thomas, S.; Vasisht, G.; Wallace, J. K.; Ward-Duong, K.; Wiktorowicz, S. J.; Wolff, S. G.; Zuckerman, B.

    2015-10-02

    Directly detecting thermal emission from young extrasolar planets allows measurement of their atmospheric compositions and luminosities, which are influenced by their formation mechanisms. Using the Gemini Planet Imager, we discovered a planet orbiting the ~20-million-year-old star 51 Eridani at a projected separation of 13 astronomical units. Near-infrared observations show a spectrum with strong methane and water-vapor absorption. Modeling of the spectra and photometry yields a luminosity (normalized by the luminosity of the Sun) of 1.6 to 4.0 × 10–6 and an effective temperature of 600 to 750 kelvin. For this age and luminosity, “hot-start” formation models indicate a mass twice that of Jupiter. As a result, this planet also has a sufficiently low luminosity to be consistent with the “cold-start” core-accretion process that may have formed Jupiter.

  8. Gemini Planet Imager Spectroscopy of the HR 8799 Planets c and d

    SciTech Connect

    Ingraham, Patrick; Marley, Mark S.; Saumon, Didier; Marois, Christian; Macintosh, Bruce; Barman, Travis; Bauman, Brian; Burrows, Adam; Chilcote, Jeffrey K.; De Rosa, Robert J.; Dillon, Daren; Doyon, René; Dunn, Jennifer; Erikson, Darren; Fitzgerald, Michael P.; Gavel, Donald; Goodsell, Stephen J.; Graham, James R.; Hartung, Markus; Hibon, Pascale; Kalas, Paul G.; Konopacky, Quinn; Larkin, James A.; Marchis, Franck; McBride, James; Millar-Blanchaer, Max; Morzinski, Katie M.; Norton, Andrew; Oppenheimer, Rebecca; Palmer, Dave W.; Patience, Jenny; Perrin, Marshall D.; Poyneer, Lisa A.; Pueyo, Laurent; Rantakyrö, Fredrik; Sadakuni, Naru; Saddlemyer, Leslie; Savransky, Dmitry; Soummer, Rémi; Sivaramakrishnan, Anand; Song, Inseok; Thomas, Sandrine; Kent Wallace, J.; Wiktorowicz, Sloane J.; Wolff, Schuyler G.

    2014-09-30

    During the first-light run of the Gemini Planet Imager we obtained K-band spectra of exoplanets HR 8799 c and d. Analysis of the spectra indicates that planet d may be warmer than planet c. Comparisons to recent patchy cloud models and previously obtained observations over multiple wavelengths confirm that thick clouds combined with horizontal variation in the cloud cover generally reproduce the planets’ spectral energy distributions.When combined with the 3 to 4μm photometric data points, the observations provide strong constraints on the atmospheric methane content for both planets. Lastly, the data also provide further evidence that future modeling efforts must include cloud opacity, possibly including cloud holes, disequilibrium chemistry, and super-solar metallicity.

  9. Tracking Publications Based on Telescope Sharing among Gemini, Subaru, and Keck: An Update

    NASA Astrophysics Data System (ADS)

    Zhang, X.; Tsang, E.; Kamisato, P.

    2015-04-01

    Gemini Observatory, Subaru Telescope, and Keck Observatory collectively operate five 8-10 meters telescopes on the summit of Mauna Kea on the Island of Hawaii and at Cerro Pachon in Chile. The three institutions began a telescope exchange program in 2005 to expand the range of backend instruments available to their respective users. A participating observatory's users can apply for telescope time from the other two observatories through the time exchange program. To measure the success of the program, we collected publications that resulted from the exchange program for the period from 2005 to 2013. Bibliometric analysis was performed on these publications to measure the productivity and impact of the exchange program. This is an enhanced and updated version of the paper presented at the IAU Commission 5 working Group Libraries session in Beijing, 2012.

  10. Observations of Rosetta Target (21) Lutetia with Keck and Gemini Adaptive Optics

    NASA Astrophysics Data System (ADS)

    Conrad, A. R.; Merline, W. J.; Drummond, J.; Carry, B.; Tamblyn, P. M.; Chapman, C. R.; Dumas, C.; Weaver, H. A.

    2009-12-01

    In support of the NASA/ESA Rosetta mission’s plans to observe asteroid (21) Lutetia during a 2010 July flyby, and in conjunction with a larger ground-based plus HST campaign to support this mission, we observed Lutetia from Keck and Gemini-North during several nights spanning 2008 Oct through 2009 Jan. Observations were made using adaptive optics in the near-IR, primarily at K-band (2.1 micron), and were timed to coincide with the asteroid's most recent opposition at a distance of about 1.4 AU. From these data, we determined Lutetia’s triaxial size and shape to be 132 x 101 x 76 km, with maximum expected uncertainties of 4 x 3 x 31 km. The spin pole is found to be at (RA, Dec) = (48, +9) deg or ecliptic (long, lat) = (49,-8) deg, with a formal uncertainty radius (not including systematics) of 3 deg. We have calibrated our technique of deriving dimensions of asteroids from AO images against Pluto and 4 satellites of Saturn with accurate diameters, and we expect that our systematics (included in the size uncertainties above) are no more than 3%. We also searched for satellites and our preliminary results indicate no detection of a satellite larger than about 1 km over a significant fraction of the Hill sphere (10-240 asteroid radii). Improved limits are expected from a more refined analysis. We are grateful for telescope time made available to us by S. Kulkarni and M. Busch (Cal Tech) for a portion of this dataset. We also thank our collaborators on Team Keck, the Keck science staff, for making possible some of these observations and for observing time granted at Gemini under NOAO time allocation. Plane-of-sky short and long axes of (21) Lutetia taken from Keck AO images on 2008 Dec 2.

  11. Interaction effects on galaxy pairs with Gemini/GMOS - II: oxygen abundance gradients

    NASA Astrophysics Data System (ADS)

    Rosa, D. A.; Dors, O. L.; Krabbe, A. C.; Hägele, G. F.; Cardaci, M. V.; Pastoriza, M. G.; Rodrigues, I.; Winge, C.

    2014-11-01

    In this paper, we derive oxygen abundance gradients from H II regions located in 11 galaxies in eight systems of close pairs. Long-slit spectra in the range 4400-7300 Å were obtained with the Gemini Multi-Object Spectrograph at Gemini South (GMOS-S). Spatial profiles of oxygen abundance in the gaseous phase along galaxy discs were obtained using calibrations based on strong emission lines (N2 and O3N2). We found oxygen gradients to be significantly flatter for all the studied galaxies than those in typical isolated spiral galaxies. Four objects in our sample, AM 1219A, AM 1256B, AM 2030A and AM 2030B, show a clear break in the oxygen abundance at galactocentric radius R/R25 between 0.2 and 0.5. For AM 1219A and AM 1256B, we found negative slopes for the inner gradients, and for AM 2030B, we found a positive slope. All three cases show a flatter behaviour to the outskirts of the galaxies. For AM 2030A, we found a positive slope for the outer gradient, while the inner gradient is almost compatible with a flat behaviour. We found a decrease of star formation efficiency in the zone that corresponds to the oxygen abundance gradient break for AM 1219A and AM 2030B. For the former, a minimum in the estimated metallicities was found very close to the break zone, which could be associated with a corotation radius. However, AM 1256B and AM 2030A, present a star formation rate maximum but not an extreme oxygen abundance value. All four interacting systems that show oxygen gradient breaks have extreme SFR values located very close to break zones.The H II regions located in close pairs of galaxies follow the same relation between the ionization parameter and the oxygen abundance as those regions in isolated galaxies.

  12. Methyl bromide emissions from a covered field: I. Experimental conditions and degradation in soil

    SciTech Connect

    Yates, S.R.; Gan, J.; Ernst, F.F.

    1996-01-01

    An experiment is described to investigate the environmental fate and transport of methyl bromide in agricultural systems. The experiment was designed to determine the dynamics of methyl bromide movement through soil, degradation, and total emissions to the atmosphere. This is of particular interest because it will allow an assessment of the environmental impacts (i.e., stratospheric ozone depletion) resulting from the agricultural use of methyl bromide. Methyl bromide was applied at a rate of 843 kg in a 3.5-ha (i.e., 240 kg/ha) field at a depth of 0.25 m and covered with a sheet of 1-mil polyethylene plastic. The maximum methyl bromide concentration in the atmosphere occurred at night between 0200 and 0600 h. During the first 3 d of the experiment, the maximum daily concentrations at 0.2 m above the soil surface were 30, 5, and 1 mg/(m{sup 3} of air), respectively. The trend of reduced emissions with time continued until the plastic was removed, when a momentary increase in the methyl bromide emissions occurred. The maximum soil gas concentration 24 h after injection was 30 g/m{sup 3} located at a 0.25-m depth. When the plastic was removed from the field (at 5.6 d), the maximum soil gas concentration was approximately 2 g/m{sup 3} at a 0.5-m depth. A mass-difference method for estimating the total methyl bromide emissions from the soil, based on degradation of methyl bromide to Br{sup -}, indicates that approximately 39% or 325 kg ({+-} 164 kg) of the applied methyl bromide was converted to Br{sup -} and, therefore, 61% or 518 kg ({+-} 164 kg) was lost via volatilization. 16 refs., 11 figs., 2 tabs.

  13. Palladium-Catalyzed Alkoxycarbonylation of Unactivated Secondary Alkyl Bromides at Low Pressure.

    PubMed

    Sargent, Brendon T; Alexanian, Erik J

    2016-06-22

    Catalytic carbonylations of organohalides are important C-C bond formations in chemical synthesis. Carbonylations of unactivated alkyl halides remain a challenge and currently require the use of alkyl iodides under harsh conditions and high pressures of CO. Herein we report a palladium-catalyzed alkoxycarbonylation of secondary alkyl bromides that proceeds at low pressure (2 atm CO) under mild conditions. Preliminary mechanistic studies are consistent with a hybrid organometallic-radical process. These reactions efficiently deliver esters from unactivated alkyl bromides across a diverse range of substrates and represent the first catalytic carbonylations of alkyl bromides with carbon monoxide.

  14. The action of structural analogues of ethidium bromide on the mitochondrial genome of yeast.

    PubMed

    Hall, R M; Mattick, J S; Nagley, P; Cobon, G S; Eastwood, F W; Linnane, A W

    1977-12-01

    We have studied the effects on the yeast mitochondrial genome of four analogues of ethidium bromide, in which the phenyl moieyt has been replaced by linear alkyl chains of lengths varying from seven to fifteen carbon atoms. These analogues are more efficient than ethidium bromide in inducing petite mutants in Saccharomyces cervisiae. The drugs also cause a loss of mtDNA from the cells in vivo; however these analogues are in fact less effective inhibitors of mitochondrial DNA replication per se, as shown by direct in vitro studies. It is concluded that these analogues are more efficient than ethidium bromide in causing the fragmentation of mitochondrial DNA in S. cervisiae. PMID:339057

  15. Aqueous Two-Phase System (ATPS) Containing Gemini (12-3-12,2Br-)and SDS 1: Phase Diagram and Properties of ATPS

    SciTech Connect

    Shang, Yazhuo; Liu, Honglai; Hu, Ying; Prausnitz, John M.

    2005-07-21

    Two phases coexist in an aqueous system that contains the two surfactants cationic gemini 12-3-12,2Br- and anionic SDS. An aqueous two-phase system (ATPS) is formed in a narrow region of the ternary phase diagram different from that of traditional aqueous cationic-anionic surfactant systems. In that region, the molar ratio of gemini to SDS varies with the total concentration of surfactants. ATPS not only has higher stability but also has longer phase separation time for the new systems than that of the traditional system. Furthermore, the optical properties of ATPS are different at different total concentrations. All of these experimental observations can be attributed to the unique properties of gemini surfactant and the synergy between the cationic gemini surfactant and the anionic surfactant SDS.

  16. Evaluation of alkali bromide salts for potential pyrochemical applications

    SciTech Connect

    Tripathy, P.K.; Gutknecht, T.Y.; Herrmann, S.D.; Fredrickson, G.L.; Lister, T.E.

    2013-07-01

    Transient techniques were employed to study the electrochemical behavior, reduction mechanism and transport properties of REBr{sub 3} (RE - La, Nd and Gd) in pure LiBr, LiBr-KBr (eutectic) and LiBr-KBr-CsBr (eutectic) melts. Gd(III) showed a reversible single step soluble-insoluble exchange phenomenon in LiBr melt at 973 K. Although La (III), Nd(III) and Gd(III) ions showed reversible behavior in eutectic LiBr-KBr melts, these ions showed a combination of temperature dependent reversible and pseudo-reversible behavior. While both La(III) and Gd(III) showed one step reduction, the reduction of Nd(III) was observed to be a two step process. La metal could be electrodeposited from the ternary electrolyte at a temperature of 673 K. Various electrochemical measurements suggest that both binary and ternary bromide melts can potentially be used to electro-deposit high purity RE metals at comparatively lower operating temperatures. (authors)

  17. Atmospheric methyl bromide: Trends and global mass balance

    SciTech Connect

    Khalil, M.A.K.; Rasmussen, R.A.; Gunawardena, R. )

    1993-02-20

    Atmospheric methyl bromide is of considerable environmental importance as the largest reservoir of gaseous bromine in the atmosphere. Bromine gases can catalytically destroy stratospheric ozone. Since agricultural activities, automobiles, biomass burning, and other human activities produce CH[sub 3]Br, it is of interest to know its global mass balance and particularly the specific sources and sinks. In this paper the authors provide a decadal time series of global CH[sub 3]Br concentrations in the Earth's atmosphere. The data show that average concentrations are about 10 pptv and during the last 4 years may be increasing at 0.3 [plus minus] 0.1 pptv/yr (3%/yr [plus minus] 1%/yr). They estimate that the atmospheric lifetime of CH[sub 3]Br that is due to reaction with OH, is about 2 years, resulting in a calculated global emission rate of about 100 Gy/yr. Ocean supersaturations of 140-180% are observed, and atmospheric concentrations over the open oceans are higher than at comparably located coastal sites. The ocean source is estimated to be about 35 Gg/yr. The remaining emissions must come from other natural sources and anthropogenic activities. The results are based on some 2,200 samples obtained over more than a decade. Mass balance calculations explain most aspects of the present data but other implications are not easily reconciled, leaving open the possibility of undiscovered sources and sinks. 20 refs., 5 figs., 4 tabs.

  18. Bioreactors for removing methyl bromide following contained fumigations

    USGS Publications Warehouse

    Miller, L.G.; Baesman, S.M.; Oremland, R.S.

    2003-01-01

    Use of methyl bromide (MeBr) as a quarantine, commodity, or structural fumigant is under scrutiny because its release to the atmosphere contributes to the depletion of stratospheric ozone. A closed-system bioreactor consisting of 0.5 L of a growing culture of a previously described bacterium, strain IMB-1, removed MeBr (> 110 ??mol L-1) from recirculating air. Strain IMB-1 grew slowly to high cell densities in the bioreactor using MeBr as its sole carbon and energy source. Bacterial oxidation of MeBr produced CO2 and hydrobromic acid (HBr), which required continuous neutralization with NaOH for the system to operate effectively. Strain IMB-1 was capable of sustained oxidation of large amounts of MeBr (170 mmol in 46 d). In an open-system bioreactor (10-L fermenter), strain IMB-1 oxidized a continuous supply of MeBr (220 ??mol L-1 in air). Growth was continuous, and 0.5 mol of MeBr was removed from the air supply in 14 d. The specific rate of MeBr oxidation was 7 ?? 10-16 mol cell-1 h-1. Bioreactors such as these can therefore be used to remove large quantities of contaminant MeBr, which opens the possibility of biodegradation as a practical means for its disposal.

  19. Olfactory stimuli provoke diffuse esophageal spasm: reversal by ipratropium bromide.

    PubMed

    Triadafilopoulos, G; Tsang, H P

    1996-10-01

    Diffuse esophageal spasm (DES) is a motor disorder of the esophageal smooth muscle characterized by multiple spontaneous contractions and by swallow-induced contractions that are of simultaneous onset, large amplitude, long duration, and repetitive occurrence. Although the pathogenesis of DES is unknown, provocative studies with cholinergic stimulation, esophageal balloon distention, or acid instillation have suggested involvement of both sensory and motor mechanisms. This report describes a patient with DES who would predictably become symptomatic with dysphagia and chest pain upon inhalation of perfume or other strong odors. Using esophageal scintigraphy to quantitate and analyze esophageal transit in this patient, we report for the first time that olfactory stimulation triggers episodes of DES and that such phenomena are mediated through the vagus nerve, because they can be ameliorated by the administration of ipratropium bromide. These observations suggest a new (sensory) pathway for the induction of DES and raise the intriguing possibility that inhaled anticholinergics may have a therapeutic role in the management of spastic esophageal motility disorders.

  20. Improved spectrometric characteristics of thallium bromide nuclear radiation detectors

    NASA Astrophysics Data System (ADS)

    Hitomi, K.; Murayama, T.; Shoji, T.; Suehiro, T.; Hiratate, Y.

    1999-06-01

    Thallium bromide (TlBr) is a compound semiconductor with a high atomic number and wide band gap. In this study, nuclear radiation detectors have been fabricated from the TlBr crystals. The TlBr crystals were grown by the horizontal travelling molten zone (TMZ) method using the materials purified by many pass zone refining. The crystals were characterized by measuring the resistivity, the mobility-lifetime ( μτ) product and the energy required to create an electron-hole pair (the ɛ value). Improved energy resolution has been obtained by the TlBr radiation detectors. At room temperature the full-width at half-maximum (FWHM) for the 59.5, 122 and 662 keV γ-ray photo peak obtained from the detectors were 3.3, 8.8 and 29.5 keV, respectively. By comparing the saturated peak position of the TlBr detector with that of the CdTe detector, the ɛ value has been estimated to be about 5.85 eV for the TlBr crystal.

  1. Nanocapsules of perfluorooctyl bromide for theranostics: from formulation to targeting

    NASA Astrophysics Data System (ADS)

    Diou, O.; Fattal, E.; Payen, T.; Bridal, S. L.; Valette, J.; Tsapis, N.

    2014-03-01

    The need to detect cancer at its early stages, as well as, to deliver chemotherapy to targeted site motivates many researchers to build theranostic platforms which combine diagnostic and therapy. Among imaging modalities, ultrasonography and Magnetic Resonance Imaging (MRI) are widely available, non invasive and complement each other. Both techniques often require the use of contrast agents. We have developed nanocapsules of perfluorooctyl bromide as dual contrast agent for both imaging modalities. The soft, amorphous polymer shell provides echogenicity, while the high-density perfluorinated liquid core allows detection by 19F MRI. We have used a shell of poly(lactide-co-glycolide) (PLGA) since this polymer is biodegradable, biocompatible and can be loaded with drugs. These capsules were shown to be efficient in vitro as contrast agents for both 19F MRI and ultrasonography. In addition, for in vivo applications a poly(ethyleneglycol) (PEG) coating promotes stability and prolonged circulation. Being stealth, nanocapsule can accumulate passively into implanted tumors by the EPR effect. We will present nanocapsule formulation and characterization, and will show promising in vivo results obtained for both ultrasonography and 19F MRI.

  2. Spectrometric study on the interaction of dodecyltrimethylammonium bromide with curcumin.

    PubMed

    Ke, Dan; Wang, Xiaoyong; Yang, Qianqian; Niu, Yumeng; Chai, Shaohu; Chen, Zhiyun; An, Xueqin; Shen, Weiguo

    2011-12-01

    The interaction between dodecyltrimethylammonium bromide (DTAB) and curcumin has been studied in pH 5.0 sodium phosphate buffer using absorption and fluorescence measurements. With increasing DTAB concentration (C(DTAB)) from 0 to 20 mM, the absorption peak of curcumin at 430 nm, corresponding to the conjugated structure of curcumin, first weakens gradually into a shoulder but increases back into one peak with much higher absorption intensity. On the contrary, as C(DTAB) increases, the initial small absorption shoulder of curcumin at 355 nm, corresponding to the feruloyl unit of curcumin, first increases gradually into a clear peak but decreases back into one shoulder until almost disappeared finally. By remaining at nearly the same wavelength, the fluorescence of curcumin first decreases at C(DTAB) lower than 5 mM and then increases gradually up to C(DTAB) = 10 mM, which is followed by sharp increases of fluorescence intensity with marked blue-shifts at higher C(DTAB). The values of anisotropy and microviscosity of curcumin obtained from the fluorescence polarization technique also showed pronounced changes at different surfactant concentrations. The interaction mechanisms of DTAB with curcumin have been presented at low, intermediate, and high surfactant concentrations, which is relating to interaction forces, surfactant aggregations, as well as structural alterations of curcumin.

  3. Evaluation of Alkali Bromide Salts for Potential Pyrochemical Applications

    SciTech Connect

    Prabhat K. Tripathy; Steven D. Herrmann; Guy L. Fredrickson; Tedd E. Lister; Toni Y. Gutknecht

    2013-10-01

    Transient techniques were employed to study the electrochemical behavior, reduction mechanism and transport properties of REBr3 (RE - La, Nd and Gd) in pure LiBr, LiBr-KBr (eutectic) and LiBr-KBr-CsBr (eutectic) melts. Gd(III) showed a reversible single step soluble-insoluble exchange phenomenon in LiBr melt at 973K. Although La (III), Nd(III) and Gd(III) ions showed reversible behavior in eutectic LiBr-KBr melts, these ions showed a combination of temperature dependent reversible and pseudo-reversible behavior. While both La(III) and Gd(III) showed one step reduction, the reduction of Nd(III) was observed to be a two step process. La metal could be electrodeposited from the ternary electrolyte at a temperature of 673K. Various electrochemical measurements suggest that both binary and ternary bromide melts can potentially be used to electrodeposit high purity RE metals at comparatively lower operating temperatures.

  4. Bacterial oxidation of methyl bromide in Mono Lake, California

    USGS Publications Warehouse

    Connell, T.L.; Joye, S.B.; Miller, L.G.; Oremland, R.S.

    1997-01-01

    The oxidation of methyl bromide (MeBr) in the water column of Mono Lake, CA, was studied by measuring the formation of H14CO3 from [14C]MeBr. Potential oxidation was detected throughout the water column, with highest rates occurring in the epilimnion (5-12 m depth). The oxidation of MeBr was eliminated by filter-sterilization, thereby demonstrating the involvement of bacteria. Vertical profiles of MeBr activity differed from those obtained for nitrification and methane oxidation, indicating that MeBr oxidation is not simply a co-oxidation process by either nitrifiers or methanotrophs. Furthermore, specific inhibitors of methane oxidation and/or nitrification (e.g., methyl fluoride, acetylene, allyl sulfide) had no effect upon the rate of MeBr oxidation in live samples. Of a variety of potential electron donors added to Mono Lake water, only trimethylamine resulted in the stimulation of MeBr oxidation. Cumulatively, these results suggest that the oxidation of MeBr in Mono Lake waters is attributable to trimethylamine-degrading methylotrophs. Neither methyl chloride nor methanol inhibited the oxidation of [14C]MeBr in live samples, indicating that these bacteria directly oxidized MeBr rather than the products of MeBr nucleophilic substitution reactions.

  5. Polarization effects in thallium bromide x-ray detectors

    SciTech Connect

    Kozorezov, A.; Wigmore, J. K.; Gostilo, V.; Shorohov, M.; Owens, A.; Quarati, F.; Webb, M. A.

    2010-09-15

    We present the results of a detailed experimental study of polarization effects in thallium bromide planar x-ray detectors. Measurements were carried out in the range 10-100 keV by scanning a highly focused x-ray beam, 50 {mu}m in diameter, from a synchrotron source across the detector. Above a certain radiation threshold the detector response showed a systematic degradation of its spectroscopic characteristics, peak channel position, peak height, and energy resolution. Using a pump-and-probe technique, we studied the dynamics of spectral degradation, the spatial extent and relaxation of the polarized region, and the dependence of the detector response on bias voltage and temperature. For comparison, we modeled polarization effects induced by the charging of traps by both electrons and holes using a model based on recent theoretical work of Bale and Szeles. We calculated the charge collection efficiency and spectral line shapes as functions of exposure time, beam position, count rate, and photon energy, and obtained credible agreement with experimental results.

  6. Fabrication of double-sided thallium bromide strip detectors

    NASA Astrophysics Data System (ADS)

    Hitomi, Keitaro; Nagano, Nobumichi; Onodera, Toshiyuki; Kim, Seong-Yun; Ito, Tatsuya; Ishii, Keizo

    2016-07-01

    Double-sided strip detectors were fabricated from thallium bromide (TlBr) crystals grown by the traveling-molten zone method using zone-purified materials. The detectors had three 3.4-mm-long strips with 1-mm widths and a surrounding electrode placed orthogonally on opposite surfaces of the crystals at approximately 6.5×6.5 mm2 in area and 5 mm in thickness. Excellent charge transport properties for both electrons and holes were observed from the TlBr crystals. The mobility-lifetime products for electrons and holes in the detector were measured to be ~3×10-3 cm2/V and ~1×10-3 cm2/V, respectively. The 137Cs spectra corresponding to the gamma-ray interaction position were obtained from the detector. An energy resolution of 3.4% of full width at half maximum for 662-keV gamma rays was obtained from one "pixel" (an intersection of the strips) of the detector at room temperature.

  7. Locations of Bromide Ions in Tetragonal Lysozyme Crystals

    NASA Technical Reports Server (NTRS)

    Lim, Kap; Nadarajah, Arunan; Forsythe, Elizabeth L.; Pusey, Marc L.

    1998-01-01

    Anions have been shown to play a dominant role in the crystallization of chicken egg-white lysozyme from salt solutions. Previous studies employing X-ray crystallography have found one chloride ion binding site in the tetragonal crystal form of the protein and four nitrate ion binding sites in the monoclinic form. In this study the anion positions in the tetragonal form were determined from the difference Fourier map obtained from lysozyme crystals grown in bromide and chloride solutions. Five possible anion-binding sites were found in this manner. Some of these sites were in pockets containing basic residues while others were near neutral, but polar, residues. The sole chloride ion binding site found in previous studies was confirmed, while four further sites were found which corresponded to the four binding sites found for nitrate ions in monoclinic crystals. The study suggests that most of the anion-binding sites in lysozyme remain unchanged even when different anions and different crystal forms of lysozyme are employed.

  8. Reactive films for mitigating methyl bromide emissions from fumigated soil.

    PubMed

    Xuan, Richeng; Ashworth, Daniel J; Luo, Lifang; Yates, Scott R

    2011-03-15

    Emissions of methyl bromide (MeBr) from agricultural fumigation can lead to depletion of the stratospheric ozone layer, and so its use is being phased out. However, as MeBr is still widely used under Critical Use Exemptions, strategies are still required to control such emissions. In this work, novel reactive films (RFs) were designed and their efficacy in limiting loss of MeBr from soil was tested. A reactive layer, containing dry ammonium thiosulfate (ATS), was sandwiched between two layers of plastic film, the lower layer being HDPE (high-density polyethylene film, which is permeable to MeBr) and the upper layer HDPE or VIF (virtually impermeable film). MeBr diffusion through, and transformation by, the RFs were tested in a stainless-steel permeability cell. Although ineffective when dry, the RFs substantially depleted MeBr when activated with water to produce ATS solution. MeBr half-life (t(1/2)) was around 9.0 h at 20 °C in the presence of activated RF, and was sensitive to temperature (t(1/2) 15.7 and 2.9 h at 10 and 40 °C, respectively). When the upper film layer was VIF, less than 0.15% of the added MeBr diffused through the film, with the remainder being transformed within the reactive layer. These findings indicate that such films have good potential to reduce MeBr loss from fumigated soils to the atmosphere.

  9. Chloride, bromide and iodide scintillators with europium doping

    DOEpatents

    Zhuravleva, Mariya; Yang, Kan

    2014-08-26

    A halide scintillator material is disclosed where the halide may comprise chloride, bromide or iodide. The material is single-crystalline and has a composition of the general formula ABX.sub.3 where A is an alkali, B is an alkali earth and X is a halide which general composition was investigated. In particular, crystals of the formula ACa.sub.1-yEu.sub.yI.sub.3 where A=K, Rb and Cs were formed as well as crystals of the formula CsA.sub.1-yEu.sub.yX.sub.3 (where A=Ca, Sr, Ba, or a combination thereof and X=Cl, Br or I or a combination thereof) with divalent Europium doping where 0.ltoreq.y.ltoreq.1, and more particularly Eu doping has been studied at one to ten mol %. The disclosed scintillator materials are suitable for making scintillation detectors used in applications such as medical imaging and homeland security.

  10. Enhancement of soil retention for phenanthrene in binary cationic gemini and nonionic surfactant mixtures: characterizing two-step adsorption and partition processes through experimental and modeling approaches.

    PubMed

    Zhao, Shan; Huang, Gordon; An, Chunjiang; Wei, Jia; Yao, Yao

    2015-04-01

    The enhancement of soil retention for phenanthrene (PHE) through the addition of a binary mixture of cationic gemini (12-2-12) and nonionic surfactants (C12E10) was investigated. The maximum apparent sorption coefficient Kd(*) reached 4247.8 mL/g through the addition of mixed 12-2-12 gemini and C12E10 surfactants, which was markedly higher than the summed individual results in the presence of individual 12-2-12 gemini (1148.6 mL/g) or C12E10 (210.0 mL/g) surfactant. However, the sorption of 12-2-12 gemini was inhibited by the increasing C12E10 dose; and a higher initial 12-2-12 gemini dose showed a higher "desorption" rate. The present study also addressed the sorption behavior of the single 12-2-12 gemini surfactant at the soil/aqueous interface. The sorption isotherm was divided into two steps to elucidate the sorption process; and the sorption schematics were proposed to elaborate the growth of surfactant aggregates corresponding to the various steps of the sorption isotherm. Finally, a two-step adsorption and partition model (TAPM) was developed to simulate the sorption process. Analysis of the equilibrium data indicated that the sorption isotherms of 12-2-12 gemini fitted the TAPM model better. Thermodynamic calculations confirmed that the 12-2-12 gemini sorption at the soil/aqueous interface was spontaneous and exothermic from 288 to 308K. PMID:25576782

  11. [Results obtained from more intensive antenatal and intranatal attention to gemini pregnancy at gynaecological hospital of Karl-Marx-Stadt region (author's transl)].

    PubMed

    Schmidt, J; Cimutta, B; Müller, K

    1979-01-01

    Studies undertaken into gemini births between 1968 and 1977 have shown that reduction in perinatal mortality has been obtainable from high-intensity programmes of antenatal and intranatal attention to multiparae. Perinatal mortality had accounted for 13.4 per cent, between 1968 and 1974, and dropped to 7.4 per cent, between 1975 and 1977. This achievement is analysed and discussed. More improvement may best be expected from earlier detection of gemini pregnancy and earlier action of intensive care.

  12. The influence of perchlorates on the fluorescence quenching of 9,10-dichloroanthracene by bromide salts in acetone

    NASA Astrophysics Data System (ADS)

    Mac, Marek; Tokarczyk, Bogdan

    1999-05-01

    Fluorescence quenching of 9,10-dichloroanthracene by lithium bromide and tetra- n-butylammonium bromide in acetone has been investigated in the presence of perchlorate salts. In the presence of LiBr, the Stern-Volmer (S-V) plots exhibit downward curvatures indicating that two species are responsible for the quenching process, namely free bromide anions and lithium bromide ion pairs. The addition of a perchlorate salt modifies the S-V dependencies due to the influence of perchlorates on the degree of lithium bromide dissociation. The association constant of lithium bromide has been determined by conductivity measurements and it agrees well with the estimates made from the fluorescence quenching measurements. The mechanism of fluorescence quenching by lithium bromide is discussed on the basis of electron transfer and the heavy-atom effect.

  13. BROMIDE'S EFFECT ON DBP FORMATION, SPECIATION, AND CONTROL: PART 1, OZONATION

    EPA Science Inventory

    The effect of variable ozone dosage and bromide concentration on the formation of organic disinfection byproducts (DBPs) and bromate were evaluated. Low ozone dosages resulted in oxidation of organic precursors, yielding decreases in the formation potential for total trihalometha...

  14. CHLORPYRIFOS TRANSFORMATION BY AQUEOUS CHLORINE IN THE PRESENCE OF BROMIDE AND NATURAL ORGANIC MATTER

    EPA Science Inventory

    The aqueous chlorination of chlorpyrifos (CP) was investigated in the presence of bromide and natural organic matter (NOM), which were identified as naturally occurring aqueous constituents that could impact CP transformation rates to the toxic product chlorpyrifos oxon (CPO). Br...

  15. Uptake and excretion of ( UC)methyl bromide as influenced by exposure concentration

    SciTech Connect

    Medinsky, M.A.; Dutcher, J.S.; Bond, J.A.; Henderson, R.F.; Mauderly, J.L.; Snipes, M.B.; Mewhinney, J.A.; Cheng, Y.S.; Birnbaum, L.S.

    1985-01-01

    Uptake of methyl bromide and pathways for excretion of UC were investigated in male Fischer-344 rats after nose-only inhalation of 50, 300, 5700, or 10,400 nmol (1.6 to 310 ppm) of ( UC)methyl bromide/liter of air for 6 hr. Fractional uptake of methyl bromide decreased at the highest concentrations, 5700 and 10,400 nmol/liter, with 37 and 27% of the inhaled methyl bromide absorbed, respectively, compared to 48% at the lower levels. Total methyl bromide absorbed was 9 or 40 mol/kg body wt after exposure to 50 or 300 nmol/liter, respectively. Elimination of UC was linearly related to the amount of methyl bromide absorbed as determined from urine, feces, expired CO2, and parent compound collected for 66 hr after the end of exposure. Exhaled UCO2 was the dominant route of excretion, with from 1.2 to 110 mol (50% of amount absorbed) exhaled, and was described by a two-component negative exponential function; 85% was exhaled with t1/2 of 4 hr, and the remaining 15% was exhaled with a t1/2 of 17 hr. The rate of exhalation of UCO2 was not affected by the amount of ( UC)methyl bromide absorbed. From 0.4 to 54 mol was excreted in urine (20% of amount absorbed). The half-time for excretion of UC in urine was approximately 10 hr, and the rate of excretion was not dependent on the amount of ( UC)methyl bromide absorbed. Little UC was exhaled as methyl bromide (<4% of the dose) or excreted in feces (<2%). At the end of 66 hr, 25% of the UC absorbed remained in the rats. Liver, kidneys, adrenals, lungs, thymus, and turbinates (maxilloturbinates, ethmoturbinates, and nasal epithelial membrane) contained the highest concentrations of UC. Results indicated that uptake of inhaled methyl bromide could be saturated. Any ( UC)methyl bromide equivalents absorbed, however, would be excreted by concentration-independent mechanisms. 20 references, 5 figures, 4 tables.

  16. Structural studies of the formation of lipoplexes between siRNA and selected bis-imidazolium gemini surfactants.

    PubMed

    Andrzejewska, W; Pietralik, Z; Skupin, M; Kozak, M

    2016-10-01

    Dicationic (gemini) surfactants are agents that can be used for the preparation of stable complexes of nucleic acids, particularly siRNA for therapeutic purposes. In this study, we demonstrated that bis-imidazolium gemini surfactants with variable lengths of dioxyalkyl linker groups (from dioxyethyl to dioxydodecyl) and dodecyl side chains are excellent for the complexation of siRNA. All of these compounds effectively complexed siRNA in a charge ratio range (p/n) of 1.5-10. The low resolution structure of siRNA oligomers was characterised by small angle scattering of synchrotron radiation (SR-SAXS) and ab initio modelling. The structures of the formed complexes were also analysed using SR-SAXS, circular dichroism studies and electrophoretic mobility tests. The most promising agents for complexation with siRNA were the surfactants that contained dioxyethyl and dioxyhexyl spacer groups. PMID:27424091

  17. Processing requirements of secure C3/I and battle management systems - Development of Gemini trusted multiple microcomputer base

    NASA Astrophysics Data System (ADS)

    Tao, T. F.; Schell, R. R.

    The present investigation is concerned with the potential applications of trusted computer system technologies in space. It is suggested that the rapidly expanding roles of new space defense missions will require space-borne command, control, communication, intelligence, and battle management (C2/I-BM) systems. The trusted computer system technology can be extended to develop new computer architectures which are able to support the broader requirements of C3/I-BM processing. The Gemini Trusted Multiple Microcomputer Base product is being developed to meet the demanding requirements and to support simultaneously the multiple capabilities. Attention is given to recent important events of trusted computer system developments, and to the Gemini system architecture.

  18. Characterizing unsaturated solute transport by simultaneous use of dye and bromide

    NASA Astrophysics Data System (ADS)

    Öhrström, P.; Hamed, Y.; Persson, M.; Berndtsson, R.

    2004-04-01

    Variability in solute transport properties in the unsaturated zone is of growing concern due to environmental hazards. By combining dye and salt tracers, a detailed description of the solute transport can be made in both time and space. In this paper, qualitative and quantitative effects of preferential flow were investigated in a sandy loam. The experimental site was equipped with 64 TDR probes. The plot was irrigated with pure water for 12 days to achieve steady state conditions. Then the plot was irrigated with a solution containing a dye tracer and KBr over three days. During the experiment, bromide concentration and soil moisture were measured hourly by the TDR probes. On the day following the last day of irrigation, a trench was dug and 14 vertical slices were excavated and photographed. A Sigma Probe (SP) was used to investigate the bromide concentration in an individual finger. The SP is a new dielectric measuring technique that gives readings of soil solution electrical conductivity. The dye photographs provided visualization of finger flow. Horizontal flow was evident in the E horizon at 0.3-0.4 m depth. Also the bromide concentration was elevated at these depths. The occurrences of high bromide as measured by the SP concentration corresponded fairly well to the dye patterns. The visible lower limit of dye stained soil corresponded to a bromide concentration of 0.10. A comparison between the bromide and dye penetration showed that the retardation factor of the dye as compared to bromide was 1.5. This is within the range reported by other authors and shows that the SP can be a useful tool to investigate the retardation of dyes as compared to bromide.

  19. The effect of pinaverium bromide (LA 1717) on the lower oesophageal sphincter.

    PubMed

    Wöltje, M; Huchzermeyer, H

    1982-01-01

    An acute, double-blind study was carried out in 8 healthy male volunteers to investigate any effect of a new antispasmodic, pinaverium bromide, compared with placebo on the lower oesophageal sphincter. Manometric measurements showed no significant differences in resting pressures either after placebo or a therapeutic dose (200 mg) of pinaverium bromide, suggesting that the active drug does not cause any impairment of function of the lower oesophageal sphincter. PMID:7128186

  20. Influence of bromide on the performance of the amphipod Hyalella azteca in reconstituted waters

    USGS Publications Warehouse

    Ivey, Chris D.; Ingersoll, Christopher G.

    2016-01-01

    Poor performance of the amphipod Hyalella azteca has been observed in exposures using reconstituted waters. Previous studies have reported success in H. azteca water-only exposures with the addition of relatively high concentrations of bromide. The present study evaluated the influence of lower environmentally representative concentrations of bromide on the response ofH. azteca in 42-d water-only exposures. Improved performance of H. azteca was observed in reconstituted waters with >0.02 mg Br/L.

  1. Reactions between a superoxide anion and alkyl bromides in dimethyl sulfoxide

    NASA Astrophysics Data System (ADS)

    Pomeshchenko, A. I.; Efimova, I. V.; Dmitruk, A. F.; Zarechnaya, O. M.; Opeida, I. A.

    2011-10-01

    The activation parameters of the reactions between a superoxide anion (O{2/·-}) and alkyl bromides are measured. An ab initio study of the transition states for various mechanisms of this reaction is performed. The mechanism of radical separation in a polar solvent becomes competitive upon an increase in the number of alkyl groups in an alkyl bromide molecule and depends on their arrangement relative to a reaction center.

  2. Stabilized thallium bromide radiation detectors and methods of making the same

    SciTech Connect

    Leao, Cedric Rocha; Lordi, Vincenzo

    2015-11-24

    According to one embodiment, a crystal includes thallium bromide (TlBr), one or more positively charged dopants, and one or more negatively charged dopants. According to another embodiment, a system includes a monolithic crystal including thallium bromide (TlBr), one or more positively charged dopants, and one or more negatively charged dopants; and a detector configured to detect a signal response of the crystal.

  3. Characterization and monitoring of Flamingos-II, a near-IR imager and spectrograph at Gemini South

    NASA Astrophysics Data System (ADS)

    Krogsrud, David; Diaz, Ruben; Ferrero, Gabriel; Mora, Marcelo; Navarete, Felipe; Schirmer, Mischa

    2015-01-01

    We present results of the characterization and continual monitoring of the Flamingos-II instrument. Currently installed at Gemini South Observatory, Flamingos-II is a near-IR imager and longslit/multi-object spectrograph. In addition to the characterization of the detector, methodologies and results of the Science Verification pipeline, Telluric corrections, and Multi-Object Spectrograph (MOS) mask design software are presented.

  4. Short gold nanorod growth revisited: the critical role of the bromide counterion.

    PubMed

    Si, Satyabrata; Leduc, Cecile; Delville, Marie-Hélène; Lounis, Brahim

    2012-01-16

    A one-step, surfactant-assisted, seed-mediated method has been utilized for the growth of short gold nanorods with reasonable yield by modifying an established synthesis protocol. Among the various parameters that influence nanorod growth, the impact of the bromide counterion has been closely scrutinized. During this study it has been shown that, irrespective of its origin, the bromide counterion [cetyltrimethylammonium bromide (CTAB) or NaBr] plays a crucial role in the formation of nanorods in the sense that there is a critical [Br(-)]/[Au(3+)] ratio (around 200) to achieve nanorods with a maximum aspect ratio. Beyond this value, bromide can be considered as a poisoning agent unless shorter nanorods are required. The use of AgNO(3) helps in symmetry breaking for gold nanorod growth, whereas the bromide counterion controls the growth kinetics by selective adsorption on the facets of the growth direction. Thus, a proper balance between bromide ions and gold cations is also one of the necessary parameters for controlling the size of the gold nanorods; this has been discussed thoroughly. The results have been discussed based on their absorption spectra and finally shape evolution has been confirmed by TEM. Due to their efficient absorption in the near-IR region, these short nanorods were used in photothermal imaging of living COS-7 cells with improved signal-to-background ratios.

  5. Effect of ferric and bromide ions on the formation and speciation of disinfection byproducts during chlorination.

    PubMed

    Liu, Shaogang; Zhu, Zhiliang; Qiu, Yanling; Zhao, Jianfu

    2011-01-01

    The effects of ferric ion, pH, and bromide on the formation and distribution of disinfection byproducts (DBPs) during chlorination were studied. Two raw water samples from Huangpu River and Yangtze River, two typical drinking water sources of Shanghai, were used for the investigation. Compared with the samples from Huangpu River, the raw water samples from Yangtze River had lower content of total organic carbon (TOC) and ferric ions, but higher bromide concentrations. Under controlled chlorination conditions, four trihalomethanes (THMs), nine haloacetic acids (HAAs), total organic halogen (TOX) and its halogen species fractions, including total organic chlorine (TOC1) and total organic bromide (TOBr), were determined. The results showed that co-existent ferric and bromide ions significantly promoted the formation of total THMs and HAAs for both raw water samples. Higher concentration of bromide ions significantly changed the speciation of the formed THMs and HAAs. There was an obvious shift to brominated species, which might result in a more adverse influence on the safety of drinking water. The results also indicated that high levels of bromide ions in raw water samples produced higher percentages of unknown TOBr.

  6. Clinical potential of aclidinium bromide in chronic obstructive pulmonary disease.

    PubMed

    Jones, Paul W

    2015-01-01

    Three long-acting muscarinic antagonists (LAMAs) are now available in Europe, providing clinicians and patients with a choice of interventions, which is important in COPD, which is clinically a heterogeneous disease. The first LAMA, tiotropium, has been widely used over the last decade as a once-daily maintenance therapy in stable COPD to improve patients' health-related quality of life and to reduce the risk of exacerbations. Administered via the HandiHaler(®) device, it is safe and well tolerated. Another new once-daily LAMA, glycopyrronium, has also been shown to improve health status and reduce exacerbations, and is well tolerated. The subject of this review is a third LAMA, aclidinium bromide, which was approved as a twice-daily maintenance bronchodilator treatment. In the pivotal Phase III clinical trials, patients receiving aclidinium achieved significantly greater improvements in lung function, reductions in breathlessness, and improvements in health status compared with placebo, for up to 24 weeks. In continuation studies, these improvements were sustained for up to 52 weeks. Pooled data showed exacerbation frequency was significantly reduced with aclidinium versus placebo. Preclinical and pharmacological studies demonstrating low systemic bioavailability and a low propensity to induce cardiac arrhythmias were translated into a favorable tolerability profile in the clinical trial program - the adverse event profile of aclidinium was similar to placebo, with a low incidence of anticholinergic and cardiac adverse events. While additional studies are needed to evaluate its full clinical potential, aclidinium is an important part of this recent expansion of LAMA therapeutic options, providing clinicians and patients with an effective and well-tolerated COPD treatment. PMID:25848244

  7. The killing of African trypanosomes by ethidium bromide.

    PubMed

    Roy Chowdhury, Arnab; Bakshi, Rahul; Wang, Jianyang; Yildirir, Gokben; Liu, Beiyu; Pappas-Brown, Valeria; Tolun, Gökhan; Griffith, Jack D; Shapiro, Theresa A; Jensen, Robert E; Englund, Paul T

    2010-12-16

    Introduced in the 1950s, ethidium bromide (EB) is still used as an anti-trypanosomal drug for African cattle although its mechanism of killing has been unclear and controversial. EB has long been known to cause loss of the mitochondrial genome, named kinetoplast DNA (kDNA), a giant network of interlocked minicircles and maxicircles. However, the existence of viable parasites lacking kDNA (dyskinetoplastic) led many to think that kDNA loss could not be the mechanism of killing. When recent studies indicated that kDNA is indeed essential in bloodstream trypanosomes and that dyskinetoplastic cells survive only if they have a compensating mutation in the nuclear genome, we investigated the effect of EB on kDNA and its replication. We here report some remarkable effects of EB. Using EM and other techniques, we found that binding of EB to network minicircles is low, probably because of their association with proteins that prevent helix unwinding. In contrast, covalently-closed minicircles that had been released from the network for replication bind EB extensively, causing them, after isolation, to become highly supertwisted and to develop regions of left-handed Z-DNA (without EB, these circles are fully relaxed). In vivo, EB causes helix distortion of free minicircles, preventing replication initiation and resulting in kDNA loss and cell death. Unexpectedly, EB also kills dyskinetoplastic trypanosomes, lacking kDNA, by inhibiting nuclear replication. Since the effect on kDNA occurs at a >10-fold lower EB concentration than that on nuclear DNA, we conclude that minicircle replication initiation is likely EB's most vulnerable target, but the effect on nuclear replication may also contribute to cell killing.

  8. Carbon isotope fractionation of methyl bromide during agricultural soil fumigations

    USGS Publications Warehouse

    Bill, M.; Miller, L.G.; Goldstein, Allen H.

    2002-01-01

    The isotopic composition of methyl bromide (CH3Br) has been suggested to be a potentially useful tracer for constraining the global CH3Br budget. In order to determine the carbon isotopic composition of CH3Br emitted from the most significant anthropogenic application (pre-plant fumigation) we directly measured the ??13C of CH3Br released during commercial fumigation. We also measured the isotopic fractionation associated with degradation in agricultural soil under typical field fumigation conditions. The isotopic composition of CH3Br collected in soil several hours after injection of the fumigant was -44.5??? and this value increased to -20.7??? over the following three days. The mean kinetic isotope effect (KIE) associated with degradation of CH3Br in agricultural soil (12???) was smaller than the reported value for methylotrophic bacterial strain IMB-1, isolated from previously fumigated agricultural soil, but was similar to methylotrophic bacterial strain CC495, isolated from a pristine forest litter zone. Using this fractionation associated with the degradation of CH3Br in agricultural soil and the mean ??13C of the industrially manufactured CH3Br (-54.4???), we calculate that the agricultural soil fumigation source has a carbon isotope signature that ranges from -52.8??? to -42.0???. Roughly 65% of industrially manufactured CH3Br is used for field fumigations. The remaining 35% is used for structural and post-harvest fumigations with a minor amount used during industrial chemical manufacturing. Assuming that the structural and post-harvest fumigation sources of CH3Br are emitted without substantial fractionation, we calculate that the ??13C of anthropogenically emitted CH3Br ranges from -53.2??? to -47.5???.

  9. Bacterial oxidation of methyl bromide in fumigated agricultural soils

    USGS Publications Warehouse

    Miller, L.G.; Connell, T.L.; Guidetti, J.R.; Oremland, R.S.

    1997-01-01

    The oxidation of [14C]methyl bromide ([14C]MeBr) to 14CO2 was measured in field experiments with soils collected from two strawberry plots fumigated with mixtures of MeBr and chloropicrin (CCI3NO2). Although these fumigants are considered potent biocides, we found that the highest rates of MeBr oxidation occurred 1 to 2 days after injection when the fields were tarped, rather than before or several days after injection. No oxidation of MeBr occurred in heat-killed soils, indicating that microbes were the causative agents of the oxidation. Degradation of MeBr by chemical and/or biological processes accounted for 20 to 50% of the loss of MeBr during fumigation, with evasion to the atmosphere inferred to comprise the remainder. In laboratory incubations, complete removal of [14C]MeBr occurred within a few days, with 47 to 67% of the added MeBr oxidized to 14CO2 and the remainder of counts associated with the solid phase. Chloropicrin inhibited the oxidation of MeBr, implying that use of this substance constrains the extent of microbial degradation of MeBr during fumigation. Oxidation was by direct bacterial attack of MeBr and not of methanol, a product of the chemical hydrolysis of MeBr. Neither nitrifying nor methane-oxidizing bacteria were sufficiently active in these soils to account for the observed oxidation of MeBr, nor could the microbial degradation of MeBr be linked to cooxidation with exogenously supplied electron donors. However, repeated addition of MeBr to live soils resulted in higher rates of its removal, suggesting that soil bacteria used MeBr as an electron donor for growth. To support this interpretation, we isolated a gram-negative, aerobic bacterium from these soils which grew with MeBr as a sole source of carbon and energy.

  10. Clinical potential of aclidinium bromide in chronic obstructive pulmonary disease

    PubMed Central

    Jones, Paul W

    2015-01-01

    Three long-acting muscarinic antagonists (LAMAs) are now available in Europe, providing clinicians and patients with a choice of interventions, which is important in COPD, which is clinically a heterogeneous disease. The first LAMA, tiotropium, has been widely used over the last decade as a once-daily maintenance therapy in stable COPD to improve patients’ health-related quality of life and to reduce the risk of exacerbations. Administered via the HandiHaler® device, it is safe and well tolerated. Another new once-daily LAMA, glycopyrronium, has also been shown to improve health status and reduce exacerbations, and is well tolerated. The subject of this review is a third LAMA, aclidinium bromide, which was approved as a twice-daily maintenance bronchodilator treatment. In the pivotal Phase III clinical trials, patients receiving aclidinium achieved significantly greater improvements in lung function, reductions in breathlessness, and improvements in health status compared with placebo, for up to 24 weeks. In continuation studies, these improvements were sustained for up to 52 weeks. Pooled data showed exacerbation frequency was significantly reduced with aclidinium versus placebo. Preclinical and pharmacological studies demonstrating low systemic bioavailability and a low propensity to induce cardiac arrhythmias were translated into a favorable tolerability profile in the clinical trial program – the adverse event profile of aclidinium was similar to placebo, with a low incidence of anticholinergic and cardiac adverse events. While additional studies are needed to evaluate its full clinical potential, aclidinium is an important part of this recent expansion of LAMA therapeutic options, providing clinicians and patients with an effective and well-tolerated COPD treatment. PMID:25848244

  11. Thermodynamic model for surfactant adsorption: Topical report. [Decyltrimethylammonium bromide

    SciTech Connect

    Woodbury, G.W. Jr.; Noll, L.A.

    1987-01-01

    A simple, semi-empirical thermodynamic model was constructed for the adsorption of solutions of surfactants onto solid surfaces. Essentially a modified finite-layer BET theory, the model is complete in that it predicts all surface thermodynamic properties. The properties of bulk solutions are considered in an exact way, and the availability of bulk thermodynamic properties is assumed. The theory has been applied satisfactorily to both the adsorption isotherm and the heat of adsorption curve for the adsorption of decyltrimethylammonium bromide (DTAB) on silica gel. In this system, the observed adsorption which occurs above the critical micelle concentration (CMC) depends on the detailed behavior of the bulk thermodynamic properties; since the measured surface properties are sensitive to bulk properties, the latter must be accounted for accurately. DTAB is the only reported surfactant system, for which both the isotherm and the heat have been measured and for which the bulk solution properties are known. A critical test of the theory awaits more data of this type; however, the theory has been tested against isotherms measured by Scamehorn, et al., and has been found to fit within experimental error below the CMC. There are many areas in which the adsorption of surfactants is of practical importance such as minerals processing, lubrication, and enhanced oil recovery. The theory should prove useful to all of these areas. In the scope of enhanced oil recovery, this theory is intended to be developed into an adsorption module for a reservoir simulator for surfactant-mineral systems whose behavior is too complex to be modeled by Henry's law or even a Langmuir isotherm. 15 refs., 6 figs., 2 tabs.

  12. Silica nanoparticles separation from water: aggregation by cetyltrimethylammonium bromide (CTAB).

    PubMed

    Liu, Y; Tourbin, M; Lachaize, S; Guiraud, P

    2013-07-01

    Nanoparticles will inevitably be found in industrial and domestic wastes in the near future and as a consequence soon in water resources. Due to their ultra-small size, nanoparticles may not only have new hazards for environment and human health, but also cause low separation efficiency by classical water treatments processes. Thus, it would be an important challenge to develop a specific treatment with suitable additives for recovery of nanoparticles from waters. For this propose, this paper presents aggregation of silica nanoparticles (Klebosol 30R50 (75nm) and 30R25 (30nm)) by cationic surfactant cetyltrimethylammonium bromide (CTAB). Different mechanisms such as charge neutralization, "depletion flocculation" or "volume-restriction", and "hydrophobic effect" between hydrocarbon tails of CTAB have been proposed to explicate aggregation results. One important finding is that for different volume concentrations between 0.05% and 0.51% of 30R50 suspensions, the same critical coagulation concentration was observed at CTAB=0.1mM, suggesting the optimized quantity of CTAB during the separation process for nanoparticles of about 75nm. Furthermore, very small quantities of CTAB (0.01mM) can make 30R25 nanosilica aggregated due to the "hydrophobic effect". It is then possible to minimize the sludge and allow the separation process as "greener" as possible by studying this case. It has also shown that aggregation mechanisms can be different for very small particles so that a special attention has to be paid to the treatment of nanoparticles contained in water and wastewaters.

  13. The fate of alternative soil fumigants to methyl bromide

    NASA Astrophysics Data System (ADS)

    Qin, R.; Gao, S.

    2011-12-01

    Soil fumigation is an important agricultural practice for the control of soil-borne pests. Since the phase-out of methyl bromide, due to its role in the depletion of stratospheric ozone, several alternatives such as 1,3-dichloropropene (1,3-D), chloropicrin (CP), and dimethyl disulfide (DMDS) are being increasingly used. The major processes and factors affecting the fate of these chemicals are evaluated. The high volatility of fumigants leads to high emission loss when no proper containment is used. Recent tarping technology using low permeability films can significantly reduce emissions. Fumigant degradation rate becomes critical to the determination of fumigation rate that affects efficacy and residence time in soil. A series of laboratory incubation experiments were carried out to determine degradation rate of 1,3-D isomers, CP and DMDS in five different soils collected from California and Florida. Fumigant degradation rates depend highly on the amounts of fumigants in soil, chemical characteristics, and soil conditions. Fumigant degradation rate were found to increase for all fumigants as the fumigant amounts in soil decreased. The changes were smaller for 1,3-D isomers compared to CP and DMDS. In soils with the lowest application rate, the degradation rate of fumigants is in the order of CP > DMDS > cis-1,3-D > trans-1,3-D. Soil and environmental factors also affect fumigant degradation rate. These findings suggest that a proper application rate should be determined for specific fumigants in a soil when using low permeability tarp in order to achieve sufficient fumigation efficacy during a certain period of time while minimizing potential surge of emissions after tarp removal and/or long residence time in soil that may cause phytotoxicity or leaching.

  14. Predicting bromide incorporation in a chlorinated indoor swimming pool.

    PubMed

    Chowdhury, Shakhawat; Mazumder, Abu Jafar; Husain, Tahir

    2016-06-01

    The water in and air above swimming pools often contain high levels of disinfection byproducts (DBPs) due to chemical reactions between chlorine- or bromine-based disinfectants and organic/inorganic matter in the source water and released from swimmers. Exposure to these DBPs, though inevitable, can pose health threats to humans. In this study, DBPs in tap water (S1), and water from a chlorinated indoor swimming pool before (S2) and after swimming (S3) were measured. The brominated species constituted the majority of DBPs formed in S1, S2, and S3. Trihalomethanes (THMs) in S3 was 6.9 (range 2.9-11.1) and 1.4 (range 0.52-2.9) times those in S1 and S2, respectively; and the haloacetic acids (HAAs) in S3 was 4.2 (range 2.5-7.5) and 1.2 (range 0.6-2.6) times those in S1 and S2, respectively. The mean THMs in air above the swimming pool before (S2-A) and after swimming (S3-A) were 72.2 and 93.0 μg/m(3), respectively, and their ranges were 36.3-105.8 and 44.1-133.6 μg/m(3), respectively. The average percentages of bromide incorporation (BI) into THMs in S1, S2, and S3 were 3.0, 9.3, and 10.6 %, respectively; and the BI into HAAs in S1, S2, and S3 were 6.6, 12.0, and 12.2 %, respectively. Several models were trained for predicting the BI into THMs and HAAs. The results indicate that additional information is required to develop predictive models for BI in swimming pools.

  15. The Killing of African Trypanosomes by Ethidium Bromide

    PubMed Central

    Roy Chowdhury, Arnab; Bakshi, Rahul; Wang, Jianyang; Yildirir, Gokben; Liu, Beiyu; Pappas-Brown, Valeria; Tolun, Gökhan; Griffith, Jack D.; Shapiro, Theresa A.; Jensen, Robert E.; Englund, Paul T.

    2010-01-01

    Introduced in the 1950s, ethidium bromide (EB) is still used as an anti-trypanosomal drug for African cattle although its mechanism of killing has been unclear and controversial. EB has long been known to cause loss of the mitochondrial genome, named kinetoplast DNA (kDNA), a giant network of interlocked minicircles and maxicircles. However, the existence of viable parasites lacking kDNA (dyskinetoplastic) led many to think that kDNA loss could not be the mechanism of killing. When recent studies indicated that kDNA is indeed essential in bloodstream trypanosomes and that dyskinetoplastic cells survive only if they have a compensating mutation in the nuclear genome, we investigated the effect of EB on kDNA and its replication. We here report some remarkable effects of EB. Using EM and other techniques, we found that binding of EB to network minicircles is low, probably because of their association with proteins that prevent helix unwinding. In contrast, covalently-closed minicircles that had been released from the network for replication bind EB extensively, causing them, after isolation, to become highly supertwisted and to develop regions of left-handed Z-DNA (without EB, these circles are fully relaxed). In vivo, EB causes helix distortion of free minicircles, preventing replication initiation and resulting in kDNA loss and cell death. Unexpectedly, EB also kills dyskinetoplastic trypanosomes, lacking kDNA, by inhibiting nuclear replication. Since the effect on kDNA occurs at a >10-fold lower EB concentration than that on nuclear DNA, we conclude that minicircle replication initiation is likely EB's most vulnerable target, but the effect on nuclear replication may also contribute to cell killing. PMID:21187912

  16. The Gemini Planet-finding Campaign: The Frequency Of Giant Planets around Debris Disk Stars

    NASA Astrophysics Data System (ADS)

    Wahhaj, Zahed; Liu, Michael C.; Nielsen, Eric L.; Biller, Beth A.; Hayward, Thomas L.; Close, Laird M.; Males, Jared R.; Skemer, Andrew; Ftaclas, Christ; Chun, Mark; Thatte, Niranjan; Tecza, Matthias; Shkolnik, Evgenya L.; Kuchner, Marc; Reid, I. Neill; de Gouveia Dal Pino, Elisabete M.; Alencar, Silvia H. P.; Gregorio-Hetem, Jane; Boss, Alan; Lin, Douglas N. C.; Toomey, Douglas W.

    2013-08-01

    We have completed a high-contrast direct imaging survey for giant planets around 57 debris disk stars as part of the Gemini NICI Planet-Finding Campaign. We achieved median H-band contrasts of 12.4 mag at 0.''5 and 14.1 mag at 1'' separation. Follow-up observations of the 66 candidates with projected separation <500 AU show that all of them are background objects. To establish statistical constraints on the underlying giant planet population based on our imaging data, we have developed a new Bayesian formalism that incorporates (1) non-detections, (2) single-epoch candidates, (3) astrometric and (4) photometric information, and (5) the possibility of multiple planets per star to constrain the planet population. Our formalism allows us to include in our analysis the previously known β Pictoris and the HR 8799 planets. Our results show at 95% confidence that <13% of debris disk stars have a >=5 M Jup planet beyond 80 AU, and <21% of debris disk stars have a >=3 M Jup planet outside of 40 AU, based on hot-start evolutionary models. We model the population of directly imaged planets as d 2 N/dMdavpropm α a β, where m is planet mass and a is orbital semi-major axis (with a maximum value of a max). We find that β < -0.8 and/or α > 1.7. Likewise, we find that β < -0.8 and/or a max < 200 AU. For the case where the planet frequency rises sharply with mass (α > 1.7), this occurs because all the planets detected to date have masses above 5 M Jup, but planets of lower mass could easily have been detected by our search. If we ignore the β Pic and HR 8799 planets (should they belong to a rare and distinct group), we find that <20% of debris disk stars have a >=3 M Jup planet beyond 10 AU, and β < -0.8 and/or α < -1.5. Likewise, β < -0.8 and/or a max < 125 AU. Our Bayesian constraints are not strong enough to reveal any dependence of the planet frequency on stellar host mass. Studies of transition disks have suggested that about 20% of stars are undergoing planet

  17. Enhanced aqueous solubility of polycyclic aromatic hydrocarbons by green diester-linked cationic gemini surfactants and their binary solutions

    NASA Astrophysics Data System (ADS)

    Panda, Manorama; Fatma, Nazish; Kabir-ud-Din

    2016-07-01

    Three homologues of a novel biodegradable diester-linked cationic gemini surfactant series, CmH2m+1 (CH3)2N+(CH2COOCH2)2N+(CH3)2CmH2m+1.2Cl- (m-E2-m; m = 12, 14, 16), were used for investigation of the solubilization of polycyclic aromatic hydrocarbons (PAHs) such as naphthalene, anthracene and pyrene in single as well as binary surfactant solutions. Physicochemical parameters of the pure/mixed systems were derived by conductivity and surface tension measurements. Dissolution capacity of the equimolar binary surfactant solutions towards the PAHs was studied from the molar solubilization ratio (MSR), micelle-water partition coefficient (Km) and free energy of solubilization (ΔGs0) of the solubilizates. Influence of hydrophobic chain length of the dimeric surfactants on solubilization was characterized. Aqueous solubility of the PAHs was enhanced linearly with concentration of the surfactant in all the pure and mixed gemini-gemini surfactant systems.

  18. Gemini: a UK twin birth cohort with a focus on early childhood weight trajectories, appetite and the family environment.

    PubMed

    van Jaarsveld, Cornelia H M; Johnson, Laura; Llewellyn, Clare; Wardle, Jane

    2010-02-01

    Gemini is a cohort study of young twins in the United Kingdom designed to assess genetic and environmental influences on early childhood weight trajectories with a focus on infant appetite and the family environment. A total of 2402 families with twins born in England and Wales between March and December 2007 agreed to participate and returned completed baseline questionnaires. The sample includes 1586 same-sex and 816 opposite-sex twins. The study is currently funded for 5 years of follow-up, but is planned to continue into early adolescence and beyond, pending funding. With current funding of the study, families will be followed up when twins are: 8 months old (baseline), and then at 15, 20, 24, 36 and 48 months of age. Gemini is in its early stages, with baseline and first follow-up data collection completed. This is the first twin cohort to focus on childhood weight gain with detailed and repeated measures of children's appetite, food preferences, activity behavior and parental feeding styles, alongside detailed and repeated collection of anthropometrics. This article reviews the rationale for the Gemini study, its representativeness and the main measures.

  19. Physical Characterization of Gemini Surfactant-Based Synthetic Vectors for the Delivery of Linear Covalently Closed (LCC) DNA Ministrings.

    PubMed

    Sum, Chi Hong; Nafissi, Nafiseh; Slavcev, Roderick A; Wettig, Shawn

    2015-01-01

    In combination with novel linear covalently closed (LCC) DNA minivectors, referred to as DNA ministrings, a gemini surfactant-based synthetic vector for gene delivery has been shown to exhibit enhanced delivery and bioavailability while offering a heightened safety profile. Due to topological differences from conventional circular covalently closed (CCC) plasmid DNA vectors, the linear topology of LCC DNA ministrings may present differences with regards to DNA interaction and the physicochemical properties influencing DNA-surfactant interactions in the formulation of lipoplexed particles. In this study, N,N-bis(dimethylhexadecyl)-α,ω-propanediammonium(16-3-16)gemini-based synthetic vectors, incorporating either CCC plasmid or LCC DNA ministrings, were characterized and compared with respect to particle size, zeta potential, DNA encapsulation, DNase sensitivity, and in vitro transgene delivery efficacy. Through comparative analysis, differences between CCC plasmid DNA and LCC DNA ministrings led to variations in the physical properties of the resulting lipoplexes after complexation with 16-3-16 gemini surfactants. Despite the size disparities between the plasmid DNA vectors (CCC) and DNA ministrings (LCC), differences in DNA topology resulted in the generation of lipoplexes of comparable particle sizes. The capacity for ministring (LCC) derived lipoplexes to undergo complete counterion release during lipoplex formation contributed to improved DNA encapsulation, protection from DNase degradation, and in vitro transgene delivery.

  20. Gemini/GMOS Spectroscopy of 26 Strong-lensing-selected Galaxy Cluster Cores

    NASA Astrophysics Data System (ADS)

    Bayliss, Matthew B.; Hennawi, Joseph F.; Gladders, Michael D.; Koester, Benjamin P.; Sharon, Keren; Dahle, Håkon; Oguri, Masamune

    2011-03-01

    We present results from a spectroscopic program targeting 26 strong-lensing cluster cores that were visually identified in the Sloan Digital Sky Survey (SDSS) and the Second Red-Sequence Cluster Survey (RCS-2). The 26 galaxy cluster lenses span a redshift range of 0.2 < z < 0.65, and our spectroscopy reveals 69 unique background sources with redshifts as high as z = 5.200. We also identify redshifts for 262 cluster member galaxies and measure the velocity dispersions and dynamical masses for 18 clusters where we have redshifts for N >= 10 cluster member galaxies. We account for the expected biases in dynamical masses of strong-lensing-selected clusters as predicted by results from numerical simulations and discuss possible sources of bias in our observations. The median dynamical mass of the 18 clusters with N >= 10 spectroscopic cluster members is M Vir = 7.84 × 1014 M sun h -1 0.7, which is somewhat higher than predictions for strong-lensing-selected clusters in simulations. The disagreement is not significant considering the large uncertainty in our dynamical data, systematic uncertainties in the velocity dispersion calibration, and limitations of the theoretical modeling. Nevertheless our study represents an important first step toward characterizing large samples of clusters that are identified in a systematic way as systems exhibiting dramatic strong-lensing features. Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: The United States, The United Kingdom, Canada, Chile, Australia, Brazil, and Argentina, with supporting data collected at the Subaru Telescope, operated by the National Astronomical Observatory of Japan; the 2.5 m Nordic Optical Telescope, operated on the island of La Palma jointly by Denmark, Finland, Iceland, Norway, and Sweden, in the Spanish Observatorio del Roque de los

  1. Hydrophilic interaction liquid chromatography-tandem mass spectrometry quantitative method for the cellular analysis of varying structures of gemini surfactants designed as nanomaterial drug carriers.

    PubMed

    Donkuru, McDonald; Michel, Deborah; Awad, Hanan; Katselis, George; El-Aneed, Anas

    2016-05-13

    Diquaternary gemini surfactants have successfully been used to form lipid-based nanoparticles that are able to compact, protect, and deliver genetic materials into cells. However, what happens to the gemini surfactants after they have released their therapeutic cargo is unknown. Such knowledge is critical to assess the quality, safety, and efficacy of gemini surfactant nanoparticles. We have developed a simple and rapid liquid chromatography electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) method for the quantitative determination of various structures of gemini surfactants in cells. Hydrophilic interaction liquid chromatography (HILIC) was employed allowing for a short simple isocratic run of only 4min. The lower limit of detection (LLOD) was 3ng/mL. The method was valid to 18 structures of gemini surfactants belonging to two different structural families. A full method validation was performed for two lead compounds according to USFDA guidelines. The HILIC-MS/MS method was compatible with the physicochemical properties of gemini surfactants that bear a permanent positive charge with both hydrophilic and hydrophobic elements within their molecular structure. In addition, an effective liquid-liquid extraction method (98% recovery) was employed surpassing previously used extraction methods. The analysis of nanoparticle-treated cells showed an initial rise in the analyte intracellular concentration followed by a maximum and a somewhat more gradual decrease of the intracellular concentration. The observed intracellular depletion of the gemini surfactants may be attributable to their bio-transformation into metabolites and exocytosis from the host cells. Obtained cellular data showed a pattern that grants additional investigations, evaluating metabolite formation and assessing the subcellular distribution of tested compounds.

  2. Chlorine-36, bromide, and the origin of spring water

    USGS Publications Warehouse

    Davis, S.N.; Cecil, L.D.; Zreda, M.; Moysey, S.

    2001-01-01

    Natural ratios of chlorine-36 (36Cl) to stable chlorine (i.e., 36Cl/Cl ?? 10-15) vary in shallow groundwater of the United States from about 50 in coastal areas to about 1400 in the northern Rocky Mountains. Ratios lower than these indicate the presence of chloride (Cl-) that has been isolated from the atmosphere for hundreds of thousands of years, if not longer. Higher ratios, which can exceed 5000, usually originate from fallout from testing thermonuclear devices in the western Pacific in the 1950s. Natural mass ratios of chloride to bromide (Cl-/Br-) in precipitation vary in the United States from about 250 in coastal areas to about 50 in the north-central states. Lower ratios may suggest contamination from human sources. Higher ratios, which may exceed 2000, commonly reflect the dissolution of halite. Seawater has a Cl-/Br- ratio of 290. Both 36Cl and Cl-/Br- ratios have been measured in 21 samples of spring water collected from springs in 10 different states. Brackish water from Saratoga Springs area in New York has low values for both 36Cl and Cl-/Br- ratios. This indicates that a large component of the water has a very deep origin. Brackish water from Alexander Springs in Florida has a low 36Cl ratio but a high Cl-/Br- ratio similar to seawater. This suggests the addition of ancient seawater that may be trapped in the aquifer. Big Spring in Iowa discharges water with a very high Cl-/Br- ratio but a moderate 36Cl ratio. The high ratio of Cl-/Br- may be produced by dissolution of road salt or agricultural chemicals. Of the 21 springs sampled, only 10 appeared to have potable water not significantly affected by human activity. Chlorine-36 from testing of nuclear devices is still being flushed out of four of the spring systems that were sampled. Thus, more than 45 years have passed since 36Cl was introduced into the aquifers feeding the springs and the systems, as yet, have not been purged. Published by Elsevier Science B.V.

  3. The ocean in near equilibrium with atmospheric methyl bromide

    NASA Astrophysics Data System (ADS)

    Hu, Lei; Yvon-Lewis, Shari; Liu, Yina; Bianchi, Thomas S.

    2012-09-01

    Saturation-anomaly measurements of methyl bromide (CH3Br) were made in the eastern Pacific (3/30-4/27, 2010) and the eastern Atlantic (10/25-11/26, 2010) to assess the oceanic saturation state as the phaseout of fumigation - non-Quarantine and Pre-Shipment (non-QPS) uses of CH3Br nears completion and atmospheric concentrations continue to decline. These cruises occurred 16 years after the Bromine Latitudinal Air-Sea Transect (BLAST) cruises, which were conducted in the same regions and first established a global oceanic net sink of -12.6 Gg yr-1 for atmospheric CH3Br in 1994. Results from this study suggest saturation anomalies of CH3Br in the surface ocean have become less negative than those observed 16 years ago as the atmospheric burden has declined over the past decade. The global net sea-to-air flux was estimated at 0 to 3 Gg yr-1 in 2010, suggesting that the ocean may become a net small source to atmospheric CH3Br. There are no significant differences between this study and previous studies for measured biological loss rate constants and calculated annual production rates, suggesting that annual production rates and biological degradation rate constants for CH3Br in the surface ocean have likely remained relatively constant over the past 16 years. When including the biological loss rate constants from this study and all previous studies, the mean global biological loss rate constant is constrained to 0.05 ± 0.01 d-1 (at a 95% confidence level). Combining chemical and eddy degradation rate constants, and using an updated gas transfer velocity, we estimate the CH3Br partial atmospheric lifetime with respect to oceanic loss to be 3.1 (2.3 to 5.0) years. Although the new partial atmospheric lifetime is about 1.3 years longer than the best prior estimate, it does not change the overall atmospheric lifetime of CH3Br, 0.8 (0.7-0.9) years.

  4. Energy and nutrient intakes of young children in the UK: findings from the Gemini twin cohort.

    PubMed

    Syrad, H; Llewellyn, C H; van Jaarsveld, C H M; Johnson, L; Jebb, S A; Wardle, J

    2016-05-28

    Data on the diets of young children in the UK are limited, despite growing evidence of the importance of early diet for long-term health. We used the largest contemporary dietary data set to describe the intake of 21-month-old children in the UK. Parents of 2336 children aged 21 months from the UK Gemini twin cohort completed 3-d diet diaries in 2008/2009. Family background information was obtained from questionnaires completed 8 months after birth. Mean total daily intakes of energy, macronutrients (g and %E) and micronutrients from food and beverages, including and excluding supplements, were derived. Comparisons with UK dietary reference values (DRV) were made using t tests and general linear regression models, respectively. Daily energy intake (kJ), protein (g) and most micronutrients exceeded DRV, except for vitamin D and Fe, where 96 or 84 % and 70 or 6 % of children did not achieve the reference nutrient intake or lower reference nutrient intake (LRNI), respectively, even with supplementation. These findings reflect similar observations in the smaller sample of children aged 18-36 months in the National Diet and Nutrition Survey. At a population level, young children in the UK are exceeding recommended daily intakes of energy and protein, potentially increasing their risk of obesity. The majority of children are not meeting the LRNI for vitamin D, largely reflecting inadequate use of the supplements recommended at this age. Parents may need more guidance on how to achieve healthy energy and nutrient intakes for young children.

  5. GEMINI: Initial behavioral results after full severance of the cervical spinal cord in mice

    PubMed Central

    Kim, C-Yoon; Oh, Hanseul; Hwang, In-Kyu; Hong, Ki-Sung

    2016-01-01

    Background: The GEMINI spinal cord fusion protocol has been developed to achieve a successful cephalosomatic anastomosis. Here, we report the preliminary data on the use of a fusogen [polyethylene glycol (PEG)] after full cervical cord transection in mice to facilitate the fusion of both ends of a sharply transected spinal cord. Methods: Cervical laminectomy and a complete, visually confirmed cervical cord (C 5) transection was performed on female albino mice (n = 16). In Group 1 (n = 8), a fusogen, (PEG) was used to bridge the gap between the cut ends of the spinal cord. Group 2 received the same spinal cord transection but was treated with saline. Outcome was assessed daily using a standard scale (modified 22-point Basso-Beattie-Bresnahan scale) and filmed on camera. Results: The PEG group (group 1) showed partial restoration of motor function after 4 weeks of observation; group 2 (placebo) did not recover any useful motor activity. Conclusion: In this preliminary experiment, PEG, but not saline, promoted partial motor recovery in mice submitted to full cervical transection. PMID:27656325

  6. The lick-index calibration of the Gemini multi-object spectrographs

    SciTech Connect

    Puzia, Thomas H.; Miller, Bryan W.; Trancho, Gelys; Basarab, Brett; Mirocha, Jordan T.; Butler, Karen E-mail: bmiller@gemini.edu

    2013-06-01

    We present the calibration of the spectroscopic Lick/IDS standard line-index system for measurements obtained with the Gemini Multi-Object Spectrographs known as GMOS-North and GMOS-South. We provide linear correction functions for each of the 25 standard Lick line indices for the B600 grism and two instrumental setups, one with 0.''5 slit width and 1 × 1 CCD pixel binning (corresponding to ∼2.5 Å spectral resolution) and the other with 0.''75 slit width and 2 × 2 binning (∼4 Å). We find small and well-defined correction terms for the set of Balmer indices Hβ, Hγ {sub A}, and Hδ {sub A} along with the metallicity sensitive indices Fe5015, Fe5270, Fe5335, Fe5406, Mg{sub 2}, and Mgb that are widely used for stellar population diagnostics of distant stellar systems. We find other indices that sample molecular absorption bands, such as TiO{sub 1} and TiO{sub 2}, with very wide wavelength coverage or indices that sample very weak molecular and atomic absorption features, such as Mg{sub 1}, as well as indices with particularly narrow passband definitions, such as Fe4384, Ca4455, Fe4531, Ca4227, and Fe5782, which are less robustly calibrated. These indices should be used with caution.

  7. Gemini/GMOS photometry of intermediate-age star clusters in the Large Magellanic Cloud

    NASA Astrophysics Data System (ADS)

    Piatti, Andrés E.; Keller, Stefan C.; Mackey, A. Dougal; Da Costa, Gary S.

    2014-10-01

    We present Gemini South GMOS g, i photometry of 14 intermediate-age Large Magellanic Cloud (LMC) star clusters, namely: NGC 2155, 2161, 2162, 2173, 2203, 2209, 2213, 2231, 2249, Hodge 6, SL 244, 505, 674, and 769, as part of a continuing project to investigate the extended main-sequence turn-off (EMSTO) phenomenon. Extensive artificial star tests were made over the observed field of view. These tests reveal the observed behaviour of photometric errors with magnitude and crowding. The cluster stellar density radial profiles were traced from star counts over the extent of the observed field. We adopt cluster radii and build colour-magnitude diagrams (CMDs) with cluster features clearly identified. We used the cluster (g, g - i) CMDs to estimate ages from the matching of theoretical isochrones. The studied LMC clusters are confirmed to be intermediate-age clusters, which range in age 9.10 < log(t) < 9.60. NGC 2162 and NGC 2249 look like new EMSTO candidates, in addition to NGC 2209, on the basis of having dual red clumps.

  8. GEMINI: Initial behavioral results after full severance of the cervical spinal cord in mice

    PubMed Central

    Kim, C-Yoon; Oh, Hanseul; Hwang, In-Kyu; Hong, Ki-Sung

    2016-01-01

    Background: The GEMINI spinal cord fusion protocol has been developed to achieve a successful cephalosomatic anastomosis. Here, we report the preliminary data on the use of a fusogen [polyethylene glycol (PEG)] after full cervical cord transection in mice to facilitate the fusion of both ends of a sharply transected spinal cord. Methods: Cervical laminectomy and a complete, visually confirmed cervical cord (C 5) transection was performed on female albino mice (n = 16). In Group 1 (n = 8), a fusogen, (PEG) was used to bridge the gap between the cut ends of the spinal cord. Group 2 received the same spinal cord transection but was treated with saline. Outcome was assessed daily using a standard scale (modified 22-point Basso-Beattie-Bresnahan scale) and filmed on camera. Results: The PEG group (group 1) showed partial restoration of motor function after 4 weeks of observation; group 2 (placebo) did not recover any useful motor activity. Conclusion: In this preliminary experiment, PEG, but not saline, promoted partial motor recovery in mice submitted to full cervical transection.

  9. Adaptive Optics for Direct Detection of Extrasolar Planets: The Gemini Planet Imager

    SciTech Connect

    Macintosh, B; Graham, J; Palmer, D; Doyon, R; Gavel, D; Larkin, J; Oppenheimer, B; Saddlemyer, L; Wallace, J K; Bauman, B; Erikson, D; Poyneer, L; Sivaramakrishnan, A; Soummer, R; Veran, J

    2007-04-24

    The direct detection of photons emitted or reflected by extrasolar planets, spatially resolved from their parent star, is a major frontier in the study of other solar systems. Direct detection will provide statistical information on planets in 5-50 AU orbits, inaccessible to current Doppler searches, and allow spectral characterization of radius, temperature, surface gravity, and perhaps composition. Achieving this will require new dedicated high-contrast instruments. One such system under construction is the Gemini Planet Imager (GPI.) This combines a high-order/high-speed adaptive optics system to control wavefront errors from the Earth's atmosphere, an advanced coronagraph to block diffraction, ultrasmooth optics, a precision infrared interferometer to measure and correct systematic errors, and a integral field spectrograph/polarimeter to image and characterize target planetary systems. We predict that GPI will be able to detect planets with brightness less than 10{sup -7} of their parent star, sufficient to observe warm self-luminous planets around a large population of targets.

  10. The Peculiar Debris Disk of HD 111520 as Resolved by the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Draper, Zachary H.; Duchêne, Gaspard; Millar-Blanchaer, Maxwell A.; Matthews, Brenda C.; Wang, Jason J.; Kalas, Paul; Graham, James R.; Padgett, Deborah; Ammons, S. Mark; Bulger, Joanna; Chen, Christine; Chilcote, Jeffrey K.; Doyon, René; Fitzgerald, Michael P.; Follette, Kate B.; Gerard, Benjamin; Greenbaum, Alexandra Z.; Hibon, Pascale; Hinkley, Sasha; Macintosh, Bruce; Ingraham, Patrick; Lafrenière, David; Marchis, Franck; Marois, Christian; Nielsen, Eric L.; Oppenheimer, Rebecca; Patel, Rahul; Patience, Jenny; Perrin, Marshall; Pueyo, Laurent; Rajan, Abhijith; Rameau, Julien; Sivaramakrishnan, Anand; Vega, David; Ward-Duong, Kimberly; Wolff, Schuyler G.

    2016-08-01

    Using the Gemini Planet Imager, we have resolved the circumstellar debris disk around HD 111520 at a projected range of ˜30–100 AU in both total and polarized H-band intensity. The disk is seen edge-on at a position angle of 165° along the spine of emission. A slight inclination and asymmetric warp are covariant and alter the interpretation of the observed disk emission. We employ three point-spread function subtraction methods to reduce the stellar glare and instrumental artifacts to confirm that there is a roughly 2:1 brightness asymmetry between the NW and SE extension. This specific feature makes HD 111520 the most extreme example of asymmetric debris disks observed in scattered light among similar highly inclined systems, such as HD 15115 and HD 106906. We further identify a tentative localized brightness enhancement and scale height enhancement associated with the disk at ˜40 AU away from the star on the SE extension. We also find that the fractional polarization rises from 10% to 40% from 0.″5 to 0.″8 from the star. The combination of large brightness asymmetry and symmetric polarization fraction leads us to believe that an azimuthal dust density variation is causing the observed asymmetry.

  11. Thermo-responsive properties driven by hydrogen bonding in aqueous cationic gemini surfactant systems.

    PubMed

    Wei, Xi-Lian; Han, Chuan-Hong; Geng, Pei-Pei; Chen, Xiao-Xiao; Guo, Yan; Liu, Jie; Sun, De-Zhi; Zhang, Jun-Hong; Yu, Meng-Jiao

    2016-02-01

    A series of unexpected thermo-responsive phenomena were discovered in an aqueous solution of the cationic gemini surfactant, 2-hydroxypropyl-1,3-bis(alkyldimethylammonium chloride) (n-3(OH)-n(2Cl), n = 14, 16), in the presence of an inorganic salt. The viscosity change trend for the 14-3(OH)-14(2Cl) system was investigated in the 20-40 °C temperature range. As the temperature increased, the viscosity of the solution first decreased to a minimum point corresponding to 27 °C, and then increased until a maximum was reached, after which the viscosity decreased again. In the 16-3(OH)-16(2Cl) system, the gelling temperature (T(gel)) and viscosity changes upon heating were similar to those in the 14-3(OH)-14(2Cl) system above 27 °C. The reversible conversion of elastic hydrogel to wormlike micelles in the aqueous solution of the 16-3(OH)-16(2Cl) system in the presence of an inorganic salt was observed at relatively low temperatures. Various techniques were used to study and verify the phase-transition processes in these systems, including rheological measurements, cryogenic transmission electron microscopy (cryo-TEM), electric conductivity, and differential scanning calorimetry. The abovementioned phenomena were explained by the formation and destruction of intermolecular hydrogen bonds, and the transition mechanisms of the aggregates were analyzed accordingly.

  12. A Gemini Planet Imager investigation of the atmosphere of the HD 95086b planet

    NASA Astrophysics Data System (ADS)

    De Rosa, Robert J.; Pueyo, Laurent; Patience, Jenny; Graham, James R.; Gemini Planet Imager Team

    2015-01-01

    We present Gemini Planet Imager (GPI) near-infrared observations of the ~5 Mjup companion to the young, dusty A-type star HD 95086, observed during the course of the verification and commissioning of the instrument. By combining binned low-resolution H and K-band IFS spectra from GPI, with literature near and mid-IR photometry, we have undertaken the most comprehensive analysis of the spectral energy distribution of HD 95086 b to-date. Comparing these observational results with atmospheric models, we constrain key parameters such as the effective temperature and surface gravity, and place the results in the context of analyses of other directly imaged planetary-mass companions (e.g. HR 8799 bcde, β Pic b), and other substellar companions at a similar age (e.g. HD 106906 b, GQ Lup b). We also comment on the sensitivity of companions interior and exterior to HD 95086 b. Lastly, we present the color-corrections derived during the course of this study that are required to transform photometry obtained with GPI in the K1 and K2 filters into both the MKO and 2MASS photometric systems, essential for the propoer interpretation of K-band photometry measurements obtained with GPI.

  13. NEAR-INFRARED OBSERVATIONS OF GQ LUP b USING THE GEMINI INTEGRAL FIELD SPECTROGRAPH NIFS

    SciTech Connect

    Lavigne, Jean-Francois; Doyon, Rene; Lafreniere, David; Marois, Christian; Barman, Travis

    2009-10-20

    We present new JHK spectroscopy (R approx 5000) of GQ Lup b, acquired with the Near-Infrared Integral Field Spectrograph and the adaptive optics system ALTAIR at the Gemini North telescope. Angular differential imaging was used in the J and H bands to suppress the speckle noise from GQ Lup A; we show that this approach can provide improvements in signal-to-noise ratio (S/N) by a factor of 2-6 for companions located at subarcsecond separations. Based on high-quality observations and Global Astrometric lnterferometer for Astrophysics synthetic spectra, we estimate the companion effective temperature to T {sub eff} = 2400 +- 100 K, its gravity to log g = 4.0 +- 0.5, and its luminosity to log(L/L {sub sun}) = -2.47 +- 0.28. Comparisons with the predictions of the DUSTY evolutionary tracks allow us to constrain the mass of GQ Lup b to 8-60 M {sub Jup}, most likely in the brown dwarf regime. Compared with the spectra published by Seifahrt and collaborators, our spectra of GQ Lup b are significantly redder (by 15%-50%) and do not show important Pabeta emission. Our spectra are in excellent agreement with the lower S/N spectra previously published by McElwain and collaborators.

  14. Constraints on the Architecture of the HD 95086 Planetary System with the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Rameau, Julien; Nielsen, Eric L.; De Rosa, Robert J.; Blunt, Sarah C.; Patience, Jenny; Doyon, René; Graham, James R.; Lafrenière, David; Macintosh, Bruce; Marchis, Franck; Bailey, Vanessa; Chilcote, Jeffrey K.; Duchene, Gaspard; Esposito, Thomas M.; Hung, Li-Wei; Konopacky, Quinn M.; Maire, Jérôme; Marois, Christian; Metchev, Stanimir; Perrin, Marshall D.; Pueyo, Laurent; Rajan, Abhijith; Savransky, Dmitry; Wang, Jason J.; Ward-Duong, Kimberly; Wolff, Schuyler G.; Ammons, S. Mark; Hibon, Pascale; Ingraham, Patrick; Kalas, Paul; Morzinski, Katie M.; Oppenheimer, Rebecca; Rantakyearö, Fredrik T.; Thomas, Sandrine

    2016-05-01

    We present astrometric monitoring of the young exoplanet HD 95086 b obtained with the Gemini Planet Imager between 2013 and 2016. A small but significant position angle change is detected at constant separation; the orbital motion is confirmed with literature measurements. Efficient Monte Carlo techniques place preliminary constraints on the orbital parameters of HD 95086 b. With 68% confidence, a semimajor axis of {61.7}-8.4+20.7 au and an inclination of 153\\fdg {0}-13.5+9.7 are favored, with eccentricity less than 0.21. Under the assumption of a coplanar planet-disk system, the periastron of HD 95086 b is beyond 51 au with 68% confidence. Therefore, HD 95086 b cannot carve the entire gap inferred from the measured infrared excess in the SED of HD 95086. We use our sensitivity to additional planets to discuss specific scenarios presented in the literature to explain the geometry of the debris belts. We suggest that either two planets on moderately eccentric orbits or three to four planets with inhomogeneous masses and orbital properties are possible. The sensitivity to additional planetary companions within the observations presented in this study can be used to help further constrain future dynamical simulations of the planet-disk system.

  15. Fabrication of narrow-slit masks for the Gemini Multiobject Spectrograph

    NASA Astrophysics Data System (ADS)

    Szeto, Kei; Stilburn, James R.; Bond, Tim; Roberts, Scott; Sebesta, Jerry; Saddlemyer, Leslie K.

    1997-03-01

    The fabrication requirements of the Gemini multi-object spectrograph (GMOS) slit mask is discussed particularly in terms of the slit-to-slit position, slit geometry and the telescope operation. The demand for precision slit masks with high quality slits of width of less than quarter arcsecond and an allowable fabrication time of two hours required examination of innovative fabrication processes and mask materials. Different fabrication processes including high precision cutting processes, water-jet and laser machining systems are evaluated according to cost, speed and efficiency, and the findings are documented. Different candidate mask materials including low thermal expansion metals and novel materials such as graphite paper and carbon-fiber composite sheet, are evaluated according to their relevant mechanical and physical properties, and the findings are also documented. In addition to identifying that the most suitable mask material is unidirectional carbon fiber sheet and the corresponding fabrication process is a Nd:YAG laser machining system, the mask handling system for GMOS is described and methodology to minimize systematic fabrication errors is also proposed.

  16. The Peculiar Debris Disk of HD 111520 as Resolved by the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    Draper, Zachary H.; Duchêne, Gaspard; Millar-Blanchaer, Maxwell A.; Matthews, Brenda C.; Wang, Jason J.; Kalas, Paul; Graham, James R.; Padgett, Deborah; Ammons, S. Mark; Bulger, Joanna; Chen, Christine; Chilcote, Jeffrey K.; Doyon, René; Fitzgerald, Michael P.; Follette, Kate B.; Gerard, Benjamin; Greenbaum, Alexandra Z.; Hibon, Pascale; Hinkley, Sasha; Macintosh, Bruce; Ingraham, Patrick; Lafrenière, David; Marchis, Franck; Marois, Christian; Nielsen, Eric L.; Oppenheimer, Rebecca; Patel, Rahul; Patience, Jenny; Perrin, Marshall; Pueyo, Laurent; Rajan, Abhijith; Rameau, Julien; Sivaramakrishnan, Anand; Vega, David; Ward-Duong, Kimberly; Wolff, Schuyler G.

    2016-08-01

    Using the Gemini Planet Imager, we have resolved the circumstellar debris disk around HD 111520 at a projected range of ˜30-100 AU in both total and polarized H-band intensity. The disk is seen edge-on at a position angle of 165° along the spine of emission. A slight inclination and asymmetric warp are covariant and alter the interpretation of the observed disk emission. We employ three point-spread function subtraction methods to reduce the stellar glare and instrumental artifacts to confirm that there is a roughly 2:1 brightness asymmetry between the NW and SE extension. This specific feature makes HD 111520 the most extreme example of asymmetric debris disks observed in scattered light among similar highly inclined systems, such as HD 15115 and HD 106906. We further identify a tentative localized brightness enhancement and scale height enhancement associated with the disk at ˜40 AU away from the star on the SE extension. We also find that the fractional polarization rises from 10% to 40% from 0.″5 to 0.″8 from the star. The combination of large brightness asymmetry and symmetric polarization fraction leads us to believe that an azimuthal dust density variation is causing the observed asymmetry.

  17. Energy and nutrient intakes of young children in the UK: findings from the Gemini twin cohort.

    PubMed

    Syrad, H; Llewellyn, C H; van Jaarsveld, C H M; Johnson, L; Jebb, S A; Wardle, J

    2016-05-28

    Data on the diets of young children in the UK are limited, despite growing evidence of the importance of early diet for long-term health. We used the largest contemporary dietary data set to describe the intake of 21-month-old children in the UK. Parents of 2336 children aged 21 months from the UK Gemini twin cohort completed 3-d diet diaries in 2008/2009. Family background information was obtained from questionnaires completed 8 months after birth. Mean total daily intakes of energy, macronutrients (g and %E) and micronutrients from food and beverages, including and excluding supplements, were derived. Comparisons with UK dietary reference values (DRV) were made using t tests and general linear regression models, respectively. Daily energy intake (kJ), protein (g) and most micronutrients exceeded DRV, except for vitamin D and Fe, where 96 or 84 % and 70 or 6 % of children did not achieve the reference nutrient intake or lower reference nutrient intake (LRNI), respectively, even with supplementation. These findings reflect similar observations in the smaller sample of children aged 18-36 months in the National Diet and Nutrition Survey. At a population level, young children in the UK are exceeding recommended daily intakes of energy and protein, potentially increasing their risk of obesity. The majority of children are not meeting the LRNI for vitamin D, largely reflecting inadequate use of the supplements recommended at this age. Parents may need more guidance on how to achieve healthy energy and nutrient intakes for young children. PMID:27093345

  18. OCTOCAM: a fast multi-channel imager and spectrograph for the Gemini telescopes

    NASA Astrophysics Data System (ADS)

    de Ugarte Postigo, Antonio

    2015-08-01

    OCTOCAM has been proposed as a future instrument for Gemini and is currently going through a feasibility study phase. Its a multi-channel instrument based on the use of high-efficiency dichroics to divide the light into eight optical and near-infrared arms. In its imaging mode it has a field of view of 3’x3’ that is simultaneously observed in eight bands. It is also designed to obtain spectroscopy from 370 to 2,400 nm in a single shot, with a spectral resolution of ~3,000. OCTOCAM will be capable of obtaining full-Stokes spectropolarimetry to study geometry and magnetic fields of astrophysical phenomena. It will be equipped with a mini-IFU (Integral Field Unit) to perform resolved spectroscopic studies in an area of a few arcseconds. Furthermore, thanks to the use of state of the art detectors, it will be able to reach high readout speeds, allowing science cases aimed at high time-resolution. We expect full frame rate reaching speeds of tens of Hertz, which will be even higher for windowed modes. This will also mean that OCTOCAM will virtually eliminate dead times in most observing modes, allowing duty cycles of roughly 100%. In this way, OCTOCAM will cover a region of the (spectral-resolution)-(spectral-coverage)-(temporal-resolution) diagram that is not occupied by any other single instrument in the world.

  19. A Systematic Deuteration Survey in the Gemini OB1 Molecular Cloud

    NASA Astrophysics Data System (ADS)

    Shirley, Yancy L.

    2014-01-01

    Recent maps of dust continuum emission from molecular clouds at submillimeter wavelengths have made it possible to survey and to study the chemistry of entire core and clump populations within a single cloud. One very strong chemical process in star-forming regions is the fractionation of deuterium in molecules which results in an increase in the deuterium ratio many orders of magnitude over the ISM [D]/[H] ratio and provides a chemical probe of cold, dense regions. We present a survey of DCO+ 3-2 emission toward the clump population in the high-mass, star-forming Gemini OB1 molecular cloud complex identified from 1.1 mm continuum imaging by the Bolocam Galactic Plane Survey (BGPS). The peak 1.1 mm continuum positions of 52 clumps were observed with the 10m Heinrich Hertz Submillimeter Telescope operated by the Arizona Radio Observatory. We compare to observations of HCO+ and H13CO+ from the BGPS spectroscopic survey of Shirley et al. to determine the deuterium ratio. We find that DCO+ emission is detected toward 90% of the clumps with a median deuterium ratio of a few percent. DCO+ fractionation anti-correlates with gas kinetic temperature and linewidth, a measure of the amount of turbulence within the clumps.

  20. Residential Proximity to Methyl Bromide Use and Birth Outcomes in an Agricultural Population in California

    PubMed Central

    Gemmill, Alison; Gunier, Robert B.; Bradman, Asa; Eskenazi, Brenda

    2013-01-01

    Background: Methyl bromide, a fungicide often used in strawberry cultivation, is of concern for residents who live near agricultural applications because of its toxicity and potential for drift. Little is known about the effects of methyl bromide exposure during pregnancy. Objective: We investigated the relationship between residential proximity to methyl bromide use and birth outcomes. Methods: Participants were from the CHAMACOS (Center for the Health Assessment of Mothers and Children of Salinas) study (n = 442), a longitudinal cohort study examining the health effects of environmental exposures on pregnant women and their children in an agricultural community in northern California. Using data from the California Pesticide Use Reporting system, we employed a geographic information system to estimate the amount of methyl bromide applied within 5 km of a woman’s residence during pregnancy. Multiple linear regression models were used to estimate associations between trimester-specific proximity to use and birth weight, length, head circumference, and gestational age. Results: High methyl bromide use (vs. no use) within 5 km of the home during the second trimester was negatively associated with birth weight (β = –113.1 g; CI: –218.1, –8.1), birth length (β = –0.85 cm; CI: –1.44, –0.27), and head circumference (β = –0.33 cm; CI: –0.67, 0.01). These outcomes were also associated with moderate methyl bromide use during the second trimester. Negative associations with fetal growth parameters were stronger when larger (5 km and 8 km) versus smaller (1 km and 3 km) buffer zones were used to estimate exposure. Conclusions: Residential proximity to methyl bromide use during the second trimester was associated with markers of restricted fetal growth in our study. PMID:23603811

  1. Bromine and bromide content in soils: Analytical approach from total reflection X-ray fluorescence spectrometry.

    PubMed

    Gallardo, Helena; Queralt, Ignasi; Tapias, Josefina; Candela, Lucila; Margui, Eva

    2016-08-01

    Monitoring total bromine and bromide concentrations in soils is significant in many environmental studies. Thus fast analytical methodologies that entail simple sample preparation and low-cost analyses are desired. In the present work, the possibilities and drawbacks of low-power total reflection X-ray fluorescence spectrometry (TXRF) for the determination of total bromine and bromide contents in soils were evaluated. The direct analysis of a solid suspension using 20 mg of fine ground soil (<63 μm) gave a 3.7 mg kg(-1) limit of detection for bromine which, in most cases, was suitable for monitoring total bromine content in soils (Br content range in soils = 5-40 mg kg(-1)). Information about bromide determination in soils is also possible by analyzing the Br content in water soil extracts. In this case, the TXRF analysis can be directly performed by depositing 10 μL of the internal standardized soil extract sample on a quartz glass reflector in a measuring time of 1500 s. The bromide limit of detection by this approach was 10 μg L(-1). Good agreement was obtained between the TXRF results for the total bromine and bromide determinations in soils and those obtained by other popular analytical techniques, e.g. energy dispersive X-ray fluorescence spectrometry (total bromine) and ionic chromatography (bromide). As a study case, the TXRF method was applied to study bromine accumulation in two agricultural soils fumigated with a methyl bromide pesticide and irrigated with regenerated waste water. PMID:27179429

  2. Bromine and bromide content in soils: Analytical approach from total reflection X-ray fluorescence spectrometry.

    PubMed

    Gallardo, Helena; Queralt, Ignasi; Tapias, Josefina; Candela, Lucila; Margui, Eva

    2016-08-01

    Monitoring total bromine and bromide concentrations in soils is significant in many environmental studies. Thus fast analytical methodologies that entail simple sample preparation and low-cost analyses are desired. In the present work, the possibilities and drawbacks of low-power total reflection X-ray fluorescence spectrometry (TXRF) for the determination of total bromine and bromide contents in soils were evaluated. The direct analysis of a solid suspension using 20 mg of fine ground soil (<63 μm) gave a 3.7 mg kg(-1) limit of detection for bromine which, in most cases, was suitable for monitoring total bromine content in soils (Br content range in soils = 5-40 mg kg(-1)). Information about bromide determination in soils is also possible by analyzing the Br content in water soil extracts. In this case, the TXRF analysis can be directly performed by depositing 10 μL of the internal standardized soil extract sample on a quartz glass reflector in a measuring time of 1500 s. The bromide limit of detection by this approach was 10 μg L(-1). Good agreement was obtained between the TXRF results for the total bromine and bromide determinations in soils and those obtained by other popular analytical techniques, e.g. energy dispersive X-ray fluorescence spectrometry (total bromine) and ionic chromatography (bromide). As a study case, the TXRF method was applied to study bromine accumulation in two agricultural soils fumigated with a methyl bromide pesticide and irrigated with regenerated waste water.

  3. Determination of methyl bromide in air samples by headspace gas chromatography

    SciTech Connect

    Woodrow, J.E.; McChesney, M.M.; Seiber, J.N.

    1988-03-01

    Methyl bromide is extensively used in agriculture (4 x 10/sup 6/ kg for 1985 in California alone as a fumigant to control nematodes, weeds, and fungi in soil and insect pests in harvested grains and nuts. Given its low boiling point (3.8/sup 0/C) and high vapor pressure (approx. 1400 Torr at 20/sup 0/C), methyl bromide will readily diffuse if not rigorously contained. Methods for determining methyl bromide and other halocarbons in air vary widely. A common practice is to trap the material from air on an adsorbent, such as polymeric resins, followed by thermal desorption either directly into the analytical instrumentation or after intermediary cryofocusing. While in some cases analytical detection limits were reasonable (parts per million range), many of the published methods were labor intensive and required special handling techniques that precluded high sample throughput. They describe here a method for the sampling and analysis of airborne methyl bromide that was designed to handle large numbers of samples through automating some critical steps of the analysis. The result was a method that allowed around-the-clock operation with a minimum of operator attention. Furthermore, the method was not specific to methyl bromide and could be used to determine other halocarbons in air.

  4. Mepenzolate bromide promotes diabetic wound healing by modulating inflammation and oxidative stress

    PubMed Central

    Zheng, Yongjun; Wang, Xingtong; Ji, Shizhao; Tian, Song; Wu, Haibin; Luo, Pengfei; Fang, He; Wang, Li; Wu, Guosheng; Xiao, Shichu; Xia, Zhaofan

    2016-01-01

    Diabetic wounds are characterized by persistent inflammation and the excessive production of reactive oxygen species, thus resulting in impaired wound healing. Mepenzolate bromide, which was originally used to treat gastrointestinal disorders in clinical settings, has recently been shown to display beneficial effects in chronic obstructive pulmonary disease and pulmonary fibrosis of a mouse model by inhibiting inflammatory responses and reducing oxidative stress. However,the role of mepenzolate bromide in diabetic wound healing is still unclear. In this study, full-thickness excisional skin wounds were created on the backs of db/db mice, and mepenzolate bromide was topically applied to the wound bed. We found that mepenzolate bromide significantly promoted diabetic wound healing by measuring wound closure rate and histomorphometric analyses. Further studies showed that inflammation was inhibited by assessing the number of macrophages and levels of pro-inflammatory cytokines and pro-healing cytokines in the wounds. Furthermore, oxidative stress was reduced by monitoring the levels of MDA and H2O2 and the activities of glutathione peroxidase and catalase in the wounds. These results demonstrated the potential application of mepenzolate bromide for treating diabetic ulcers and other chronic wounds in clinics. PMID:27398156

  5. [Bowel obstruction-induced cholinergic crisis with progressive respiratory failure following distigmine bromide treatment].

    PubMed

    Kobayashi, Kazuki; Sekiguchi, Hiroshi; Sato, Nobuhiro; Hirose, Yasuo

    2016-03-01

    A 54-year-old female experienced rapid respiratory failure while being transported in an ambulance to our emergency department for evaluation and management of constipation and abdominal pain. The patient was on treatment with distigmine bromide for postoperative urination disorder and magnesium oxide for constipation. Increased salivary secretions, diminished respiratory excursion, type 2 respiratory failure (PaCO2 : 65 mmHg), low serum cholinesterase, and hypermagnesemia were detected. Imaging studies revealed that the patient had bilateral aspiration pneumonia, fecal impaction in the rectum, and a distended colon causing ileus. The patient was mechanically ventilated and was weaned off the ventilator on day 3. Therapeutic drug monitoring after discharge revealed that the serum level of distigmine bromide on admission was markedly elevated (377.8 ng/mL vs. the normal therapeutic level of 5-10 ng/mL). Distigmine bromide induced a cholinergic crisis with a resultant increase in airway secretions and respiratory failure. In this particular case, orally administered distigmine bromide was excessively absorbed because of prolonged intestinal transit time secondary to fecal impaction and sluggish bowel movement; this caused a cholinergic crisis and hypermagnesemia contributing to respiratory failure. Clinicians should be aware that bowel obstruction in a patient treated with distigmine bromide can increase the risk of a cholinergic crisis. PMID:27255021

  6. Mepenzolate bromide promotes diabetic wound healing by modulating inflammation and oxidative stress.

    PubMed

    Zheng, Yongjun; Wang, Xingtong; Ji, Shizhao; Tian, Song; Wu, Haibin; Luo, Pengfei; Fang, He; Wang, Li; Wu, Guosheng; Xiao, Shichu; Xia, Zhaofan

    2016-01-01

    Diabetic wounds are characterized by persistent inflammation and the excessive production of reactive oxygen species, thus resulting in impaired wound healing. Mepenzolate bromide, which was originally used to treat gastrointestinal disorders in clinical settings, has recently been shown to display beneficial effects in chronic obstructive pulmonary disease and pulmonary fibrosis of a mouse model by inhibiting inflammatory responses and reducing oxidative stress. However,the role of mepenzolate bromide in diabetic wound healing is still unclear. In this study, full-thickness excisional skin wounds were created on the backs of db/db mice, and mepenzolate bromide was topically applied to the wound bed. We found that mepenzolate bromide significantly promoted diabetic wound healing by measuring wound closure rate and histomorphometric analyses. Further studies showed that inflammation was inhibited by assessing the number of macrophages and levels of pro-inflammatory cytokines and pro-healing cytokines in the wounds. Furthermore, oxidative stress was reduced by monitoring the levels of MDA and H2O2 and the activities of glutathione peroxidase and catalase in the wounds. These results demonstrated the potential application of mepenzolate bromide for treating diabetic ulcers and other chronic wounds in clinics. PMID:27398156

  7. Methyl bromide: ocean sources, ocean sinks, and climate sensitivity.

    PubMed

    Anbar, A D; Yung, Y L; Chavez, F P

    1996-03-01

    The oceans play an important role in the geochemical cycle of methyl bromide (CH3Br), the major carrier of O3-destroying bromine to the stratosphere. The quantity of CH3Br produced annually in seawater is comparable to the amount entering the atmosphere each year from natural and anthropogenic sources. The production mechanism is unknown but may be biological. Most of this CH3Br is consumed in situ by hydrolysis or reaction with chloride. The size of the fraction which escapes to the atmosphere is poorly constrained; measurements in seawater and the atmosphere have been used to justify both a large oceanic CH3Br flux to the atmosphere and a small net ocean sink. Since the consumption reactions are extremely temperature-sensitive, small temperature variations have large effects on the CH3Br concentration in seawater, and therefore on the exchange between the atmosphere and the ocean. The net CH3Br flux is also sensitive to variations in the rate of CH3Br production. We have quantified these effects using a simple steady state mass balance model. When CH3Br production rates are linearly scaled with seawater chlorophyll content, this model reproduces the latitudinal variations in marine CH3Br concentrations observed in the east Pacific Ocean by Singh et al. [1983] and by Lobert et al. [1995]. The apparent correlation of CH3Br production with primary production explains the discrepancies between the two observational studies, strengthening recent suggestions that the open ocean is a small net sink for atmospheric CH3Br, rather than a large net source. The Southern Ocean is implicated as a possible large net source of CH3Br to the atmosphere. Since our model indicates that both the direction and magnitude of CH3Br exchange between the atmosphere and ocean are extremely sensitive to temperature and marine productivity, and since the rate of CH3Br production in the oceans is comparable to the rate at which this compound is introduced to the atmosphere, even small

  8. Methyl bromide: ocean sources, ocean sinks, and climate sensitivity.

    PubMed

    Anbar, A D; Yung, Y L; Chavez, F P

    1996-03-01

    The oceans play an important role in the geochemical cycle of methyl bromide (CH3Br), the major carrier of O3-destroying bromine to the stratosphere. The quantity of CH3Br produced annually in seawater is comparable to the amount entering the atmosphere each year from natural and anthropogenic sources. The production mechanism is unknown but may be biological. Most of this CH3Br is consumed in situ by hydrolysis or reaction with chloride. The size of the fraction which escapes to the atmosphere is poorly constrained; measurements in seawater and the atmosphere have been used to justify both a large oceanic CH3Br flux to the atmosphere and a small net ocean sink. Since the consumption reactions are extremely temperature-sensitive, small temperature variations have large effects on the CH3Br concentration in seawater, and therefore on the exchange between the atmosphere and the ocean. The net CH3Br flux is also sensitive to variations in the rate of CH3Br production. We have quantified these effects using a simple steady state mass balance model. When CH3Br production rates are linearly scaled with seawater chlorophyll content, this model reproduces the latitudinal variations in marine CH3Br concentrations observed in the east Pacific Ocean by Singh et al. [1983] and by Lobert et al. [1995]. The apparent correlation of CH3Br production with primary production explains the discrepancies between the two observational studies, strengthening recent suggestions that the open ocean is a small net sink for atmospheric CH3Br, rather than a large net source. The Southern Ocean is implicated as a possible large net source of CH3Br to the atmosphere. Since our model indicates that both the direction and magnitude of CH3Br exchange between the atmosphere and ocean are extremely sensitive to temperature and marine productivity, and since the rate of CH3Br production in the oceans is comparable to the rate at which this compound is introduced to the atmosphere, even small

  9. Methyl bromide: ocean sources, ocean sinks, and climate sensitivity

    NASA Technical Reports Server (NTRS)

    Anbar, A. D.; Yung, Y. L.; Chavez, F. P.

    1996-01-01

    The oceans play an important role in the geochemical cycle of methyl bromide (CH3Br), the major carrier of O3-destroying bromine to the stratosphere. The quantity of CH3Br produced annually in seawater is comparable to the amount entering the atmosphere each year from natural and anthropogenic sources. The production mechanism is unknown but may be biological. Most of this CH3Br is consumed in situ by hydrolysis or reaction with chloride. The size of the fraction which escapes to the atmosphere is poorly constrained; measurements in seawater and the atmosphere have been used to justify both a large oceanic CH3Br flux to the atmosphere and a small net ocean sink. Since the consumption reactions are extremely temperature-sensitive, small temperature variations have large effects on the CH3Br concentration in seawater, and therefore on the exchange between the atmosphere and the ocean. The net CH3Br flux is also sensitive to variations in the rate of CH3Br production. We have quantified these effects using a simple steady state mass balance model. When CH3Br production rates are linearly scaled with seawater chlorophyll content, this model reproduces the latitudinal variations in marine CH3Br concentrations observed in the east Pacific Ocean by Singh et al. [1983] and by Lobert et al. [1995]. The apparent correlation of CH3Br production with primary production explains the discrepancies between the two observational studies, strengthening recent suggestions that the open ocean is a small net sink for atmospheric CH3Br, rather than a large net source. The Southern Ocean is implicated as a possible large net source of CH3Br to the atmosphere. Since our model indicates that both the direction and magnitude of CH3Br exchange between the atmosphere and ocean are extremely sensitive to temperature and marine productivity, and since the rate of CH3Br production in the oceans is comparable to the rate at which this compound is introduced to the atmosphere, even small

  10. Current and Potential Future Bromide Loads from Coal-Fired Power Plants in the Allegheny River Basin and Their Effects on Downstream Concentrations.

    PubMed

    Good, Kelly D; VanBriesen, Jeanne M

    2016-09-01

    The presence of bromide in rivers does not affect ecosystems or present a human health risk; however, elevated concentrations of bromide in drinking water sources can lead to difficulty meeting drinking water disinfection byproduct (DBP) regulations. Recent attention has focused on oil and gas wastewater and coal-fired power plant wet flue gas desulfurization (FGD) wastewater bromide discharges. Bromide can be added to coal to enhance mercury removal, and increased use of bromide at some power plants is expected. Evaluation of potential increases in bromide concentrations from bromide addition for mercury control is lacking. The present work utilizes bromide monitoring data in the Allegheny River and a mass-balance approach to elucidate bromide contributions from anthropogenic and natural sources under current and future scenarios. For the Allegheny River, the current bromide is associated approximately 49% with oil- and gas-produced water discharges and 33% with coal-fired power plants operating wet FGD, with 18% derived from natural sources during mean flow conditions in August. Median wet FGD bromide loads could increase 3-fold from 610 to 1900 kg/day if all plants implement bromide addition for mercury control. Median bromide concentrations in the lower Allegheny River in August would rise to 410, 200, and 180 μg/L under low-, mean-, and high-flow conditions, respectively, for the bromide-addition scenario. PMID:27538590

  11. Current and Potential Future Bromide Loads from Coal-Fired Power Plants in the Allegheny River Basin and Their Effects on Downstream Concentrations.

    PubMed

    Good, Kelly D; VanBriesen, Jeanne M

    2016-09-01

    The presence of bromide in rivers does not affect ecosystems or present a human health risk; however, elevated concentrations of bromide in drinking water sources can lead to difficulty meeting drinking water disinfection byproduct (DBP) regulations. Recent attention has focused on oil and gas wastewater and coal-fired power plant wet flue gas desulfurization (FGD) wastewater bromide discharges. Bromide can be added to coal to enhance mercury removal, and increased use of bromide at some power plants is expected. Evaluation of potential increases in bromide concentrations from bromide addition for mercury control is lacking. The present work utilizes bromide monitoring data in the Allegheny River and a mass-balance approach to elucidate bromide contributions from anthropogenic and natural sources under current and future scenarios. For the Allegheny River, the current bromide is associated approximately 49% with oil- and gas-produced water discharges and 33% with coal-fired power plants operating wet FGD, with 18% derived from natural sources during mean flow conditions in August. Median wet FGD bromide loads could increase 3-fold from 610 to 1900 kg/day if all plants implement bromide addition for mercury control. Median bromide concentrations in the lower Allegheny River in August would rise to 410, 200, and 180 μg/L under low-, mean-, and high-flow conditions, respectively, for the bromide-addition scenario.

  12. Inhibitory effect of pinaverium bromide on gastrointestinal contractile activity in conscious dogs.

    PubMed

    Itoh, Z; Takahashi, I

    1981-01-01

    The inhibitory effect of 4-(6-bromoveratryl)-4-(2-[2-(6,6-dimethyl-2-norpinyl)-ethoxy]-ethyl)-morpholinium hydroxide (pinaverium bromide), a quaternary ammonium derivative, on the contractile activity of the gastrointestinal tract from the stomach to the colon was investigated in six conscious dogs. Gastrointestinal motor activity was monitored by means of chronically implanted force transducers. Pinaverium bromide was continuously administered i.v. for 30 min in doses of 10 and 20 mg/kg/h during both the digestive and interdigestive states. It was found that pinaverium bromide strongly inhibited gastrointestinal contractile activity during both the digestive and interdigestive states; contractions in the stomach were most strongly inhibited; however, those in the small and large bowels were also significantly inhibited. No significant side effects in the circulatory and respiratory systems and the gastrointestinal tract such as nausea, vomiting or diarrhea were observed during and after the infusion of this agent. PMID:7197953

  13. Dispersion characteristics and sinks for methyl bromide vapors downwind of treated agricultural fields

    SciTech Connect

    Seiber, J.N.; Woodrow, J.E.; Dowling, K.

    1995-12-31

    A study of methyl bromide volatilization and fate from a treated agricultural field was conducted in Monterey County, California, in 1994. Air concentrations were measured above and downwind from the field with the objective of comparing vertical and horizontal flux terms. Another objective was to compare observed downwind concentrations with those predicted by the Industrial Source Complex model, to begin the process of identifying potential sinks which might scavenge methyl bromide from the atmosphere. The final objective was to determine the limit of detection of our analytical method for airborne methyl bromide using field samples representing a wide range of concentrations. A description of the methods and results of the study will be presented, along with a discussion of data quality and interpretation.

  14. 2-O-substituted cyclodextrins as reversal agents for the neuromuscular blocker rocuronium bromide.

    PubMed

    Tarver, Gary J; Grove, Simon J A; Buchanan, Kirsteen; Bom, Anton; Cooke, Andrew; Rutherford, Samantha J; Zhang, Ming Qiang

    2002-06-01

    A series of secondary face modified cyclodextrins (CDs) were synthesised with the aim of constructing host molecules capable of forming host-guest complexes with neuromuscular blockers, especially with rocuronium bromide. Perfacial 2-O-substitution of gamma-CD with 4-carboxybenzyl resulted in a CD host molecule 1 that forms a 1:1 binary complex with rocuronium bromide (K(a) 6.2 x 10(5) M(-1)). The biological activities of this compound and other derivatives as reversal agents of rocuronium bromide were examined in vitro (mouse hemi-diaphragm) and in vivo (anaesthetized guinea pigs). The host molecule 1 was found to exert potent reversal activity (ED(50) 0.21 micromol/kg, iv) against rocuronium-induced neuromuscular block, and thus proved the viability of using host molecules as antidotes of a biologically active compound.

  15. Synthesis and Characterization of the Antimicrobial 4-AMINO-DECYLPYRIDINIUM Bromide Cationic Surfactant

    NASA Astrophysics Data System (ADS)

    Madaan, Parag; Tyagi, V. K.

    4-Amino-decylpyridinium bromide (ADPBr), an antimicrobial surface active agent, was synthesized by quaternization of 4-aminopyridine (AP) with decyl bromide (DBr). The reaction was carried out at 1:1.2 molar ratio of reactants (4-aminopyridine and decyl bromide, respectively) at 200°C for 10 min. The maximum yield of the product was 74.6%. The structure of the synthesized product was characterized by using modern analytical techniques, such as FT-IR, 1H NMR, and 13C NMR. The antimicrobial activity of the salt was evaluated with minimum inhibition concentration method and showed good activity against gram-negative bacteria. The MIC of the salt was found to be 600 ppm for 2 × 104 CFU/mL of E. coli.

  16. Seeded Growth of Monodisperse Gold Nanorods Using Bromide-Free Surfactant Mixtures

    SciTech Connect

    Ye, XC; Gao, YZ; Chen, J; Reifsnyder, DC; Zheng, C; Murray, CB

    2013-05-01

    We demonstrate for the first time that monodisperse gold nanorods (NRs) with broadly tunable dimensions and longitudinal surface plasmon resonances can be synthesized using a bromide-free surfactant mixture composed of alkyltrimethylammonium chloride and sodium oleate. It is found that uniform gold NRs can be obtained even with an iodide concentration approaching 100 mu M in the growth solution. In contrast to conventional wisdom, our results provide conclusive evidence that neither bromide as the surfactant counterion nor a high concentration of bromide ions in the growth solution is essential for gold NR formation. Correlated electron microscopy study of three-dimensional structures of gold NRs reveals a previously unprecedented octagonal prismatic structure enclosed predominantly by high index {310} crystal planes. These findings should have profound implications for a comprehensive mechanistic understanding of seeded growth of anisotropic metal nanocrystals.

  17. Chloride/bromide ratios in leachate derived from farm-animal waste.

    PubMed

    Hudak, Paul F

    2003-01-01

    Ratios of conservative chemicals have been used to identify sources of groundwater contamination. While chloride/bromide ratios have been reported for several common sources of groundwater contamination, little work has been done on leachate derived from farm-animal waste. In this study, chloride/bromide ratios were measured in leachate derived from longhorn-cattle, quarterhorse, and pygme-goat waste at a farm in Abilene, Texas, USA. (Minimum, median, and maximum) chloride/bromide ratios of (66.5, 85.6, and 167), (119, 146, and 156), and (35.4, 57.8, and 165) were observed for cattle, horses, and goats, respectively. These ratios are below typical values for domestic wastewater and within the range commonly observed for oilfield brine. Results of this study have important implications for identifying sources of contaminated groundwater in settings with significant livestock and/or oil production.

  18. Salty glycerol versus salty water surface organization: bromide and iodide surface propensities.

    PubMed

    Huang, Zishuai; Hua, Wei; Verreault, Dominique; Allen, Heather C

    2013-07-25

    Salty NaBr and NaI glycerol solution interfaces are examined in the OH stretching region using broadband vibrational sum frequency generation (VSFG) spectroscopy. Raman and infrared (IR) spectroscopy are used to further understand the VSFG spectroscopic signature. The VSFG spectra of salty glycerol solutions reveal that bromide and iodide anions perturb the interfacial glycerol organization in a manner similar as that found in aqueous halide salt solutions, thus confirming the presence of bromide and iodide anions at the glycerol surface. Surface tension measurements are consistent with the surface propensity suggested by the VSFG data and also show that the surface excess increases with increasing salt concentration, similar to that of water. In addition, iodide is shown to have more surface prevalence than bromide, as has also been determined from aqueous solutions. These results suggest that glycerol behaves similarly to water with respect to surface activity and solvation of halide anions at its air/liquid interface. PMID:23663033

  19. SN 1987A after 18 Years: Mid-Infrared GEMINI and SPITZER Observations of the Remnant

    NASA Technical Reports Server (NTRS)

    Bouchet, Patrice; Dwek, Eli; Danziger, John; Arendt, Richard G.; DeBuizer, James M.; Park, Sangwook; Suntzeff, Nicholas B.; Kirshner, Robert P.; Challis, Peter

    2007-01-01

    We present high resolution 11.7 and 18.3 micron mid-IR images of SN 1987A obtained on day 6526 since the explosion with the Thermal-Region Camera and Spectrograph (T-ReCS) attached to the Gemini South 8m telescope. The 11.7 micron flux has increased significantly since our last observations on day 6067. The images clearly show that all the emission arises from the equatorial ring (ER). Nearly contemporaneous spectra obtained on day 6184 with the MIPS at 24 micron, on day 6130 with the IRAC in 3.6- 8 micron region, and on day 6190 with the IRS in the 12-37 micron instruments on board the Spitzer Space Telescope's show that the emission consists of thermal emission from silicate dust that condensed out in the red giant wind of the progenitor star. The dust temperature is 1662(sup +18) (sub -12) K, and the emitting dust mass is (2.6(sup +2.0 (sub -1.4)) x 10 (exp -6) M(solar). Lines of [Ne II] 12.82 micron and [Ne III] 15.56 pm are clearly present in the Spitzer spectrum, as well as a weak [Si II] 3 34.8 micron line. We also detect two lines near 26 micron which we tentatively ascribe to [Fe II] 25.99 pm and [0 IV] 25.91 micron. Comparison of the mid-IR Gemini 11.7 micron image with X-ray images obtained by Chandra, UV-optical images obtained by HST, and radio synchrotron images obtained by the ATCA show generally good correlation of the images across all wavelengths. Because of the limited resolution of the mid-IR images we cannot uniquely determine the location. or heating mechanism of the dust giving rise to the emission. The dust could be collisionally heated by the X-ray emitting plasma, providing a unique diagnostic of plasma conditions. Alternatively, the dust could be radiatively heated in the dense UV-optical knots that are overrun by the advancing supernova blast wave. In either case the dust-to-gas mass ratio in the circumstellar medium around the supernova is significantly lower than that in the general interstellar medium of the LMC, suggesting either a

  20. DETECTABILITY OF EXOPLANETS IN THE {beta} PIC MOVING GROUP WITH THE GEMINI PLANET IMAGER

    SciTech Connect

    Kataria, Tiffany; Simon, Michal

    2010-07-15

    We model the detectability of exoplanets around stars in the {beta} Pic Moving Group (BPMG) using the Gemini Planet Imager (GPI), a coronagraphic instrument designed to detect companions by imaging. Members of the BPMG are considered promising targets for exoplanet searches because of their youth ({approx}12 Myr) and proximity (median distance {approx}35 pc). We wrote a modeling procedure to generate hypothetical companions of given mass, age, eccentricity, and semi-major axis, and place them around BPMG members that fall within the V-band range of the GPI. We count companions lying within the GPI's field of view and H-band fluxes that have a host-companion flux ratio placing them within its sensitivity as possible detections. The fraction of companions that could be detected depends on their brightness at 12 Myr, and hence formation mechanism, and on their distribution of semi-major axes. We used brightness models for formation by disk instability and core-accretion. We considered the two extreme cases of the semi-major axis distribution-the log-normal distribution of the nearby F- and G-type stars and a power-law distribution indicated by the exoplanets detected by the radial velocity technique. We find that the GPI could detect exoplanets of all the F and G spectral type stars in the BPMG sample with a probability that depends on the brightness model and semi-major axis distribution. At spectral type K-M1, exoplanet detectability depends on brightness and hence distance of the host star. GPI will be able to detect the companions of M stars later than M1 only if they are closer than 10 pc. Of the four A stars in the BPMG sample, only one has a V-band brightness in the range of GPI; the others are too bright.

  1. Gemini Planet Imager Observations of the AU Microscopii Debris Disk: Asymmetries within One Arcsecond

    NASA Astrophysics Data System (ADS)

    Wang, Jason J.; Graham, James R.; Pueyo, Laurent; Nielsen, Eric L.; Millar-Blanchaer, Max; De Rosa, Robert J.; Kalas, Paul; Ammons, S. Mark; Bulger, Joanna; Cardwell, Andrew; Chen, Christine; Chiang, Eugene; Chilcote, Jeffrey K.; Doyon, René; Draper, Zachary H.; Duchêne, Gaspard; Esposito, Thomas M.; Fitzgerald, Michael P.; Goodsell, Stephen J.; Greenbaum, Alexandra Z.; Hartung, Markus; Hibon, Pascale; Hinkley, Sasha; Hung, Li-Wei; Ingraham, Patrick; Larkin, James E.; Macintosh, Bruce; Maire, Jerome; Marchis, Franck; Marois, Christian; Matthews, Brenda C.; Morzinski, Katie M.; Oppenheimer, Rebecca; Patience, Jenny; Perrin, Marshall D.; Rajan, Abhijith; Rantakyrö, Fredrik T.; Sadakuni, Naru; Serio, Andrew; Sivaramakrishnan, Anand; Soummer, Rémi; Thomas, Sandrine; Ward-Duong, Kimberly; Wiktorowicz, Sloane J.; Wolff, Schuyler G.

    2015-10-01

    We present Gemini Planet Imager (GPI) observations of AU Microscopii, a young M dwarf with an edge-on, dusty debris disk. Integral field spectroscopy and broadband imaging polarimetry were obtained during the commissioning of GPI. In our broadband imaging polarimetry observations, we detect the disk only in total intensity and find asymmetries in the morphology of the disk between the southeast (SE) and northwest (NW) sides. The SE side of the disk exhibits a bump at 1″ (10 AU projected separation) that is three times more vertically extended and three times fainter in peak surface brightness than the NW side at similar separations. This part of the disk is also vertically offset by 69 ± 30 mas to the northeast at 1″ when compared to the established disk midplane and is consistent with prior Atacama Large Millimeter/submillimeter Array and Hubble Space Telescope/Space Telescope Imaging Spectrograph observations. We see hints that the SE bump might be a result of detecting a horizontal sliver feature above the main disk that could be the disk backside. Alternatively, when including the morphology of the NW side, where the disk midplane is offset in the opposite direction ∼50 mas between 0.″4 and 1.″2, the asymmetries suggest a warp-like feature. Using our integral field spectroscopy data to search for planets, we are 50% complete for ∼4 MJup planets at 4 AU. We detect a source, resolved only along the disk plane, that could either be a candidate planetary mass companion or a compact clump in the disk.

  2. Gemini Planet Imager observations of the AU Microscopii debris disk: Asymmetries within one arcsecond

    SciTech Connect

    Wang, Jason J.; Graham, James R.; Pueyo, Laurent; Nielsen, Eric L.; Millar-Blanchaer, Max; De Rosa, Robert J.; Kalas, Paul; Ammons, S. Mark; Bulger, Joanna; Cardwell, Andrew; Chen, Christine; Chiang, Eugene; Chilcote, Jeffrey K.; Doyon, René; Draper, Zachary H.; Duchêne, Gaspard; Fitzgerald, Michael P.; Goodsell, Stephen J.; Greenbaum, Alexandra Z.; Hartung, Markus; Hibon, Pascale; Hinkley, Sasha; Hung, Li -Wei; Ingraham, Patrick; Larkin, James E.; Macintosh, Bruce; Maire, Jerome; Marchis, Franck; Marois, Christian; Matthews, Brenda C.; Morzinski, Katie M.; Oppenheimer, Rebecca; Patience, Jenny; Perrin, Marshall D.; Rajan, Abhijith; Rantakyrö, Fredrik T.; Sadakuni, Naru; Serio, Andrew; Sivaramakrishnan, Anand; Soummer, Rémi; Thomas, Sandrine; Ward-Duong, Kimberly; Wiktorowicz, Sloane J.; Wolff, Schuyler G.

    2015-09-23

    We present Gemini Planet Imager (GPI) observations of AU Microscopii, a young M dwarf with an edge-on, dusty debris disk. Integral field spectroscopy and broadband imaging polarimetry were obtained during the commissioning of GPI. In our broadband imaging polarimetry observations, we detect the disk only in total intensity and find asymmetries in the morphology of the disk between the southeast (SE) and northwest (NW) sides. The SE side of the disk exhibits a bump at 1'' (10 AU projected separation) that is three times more vertically extended and three times fainter in peak surface brightness than the NW side at similar separations. This part of the disk is also vertically offset by 69 ± 30 mas to the northeast at 1'' when compared to the established disk midplane and is consistent with prior Atacama Large Millimeter/submillimeter Array and Hubble Space Telescope/Space Telescope Imaging Spectrograph observations. We see hints that the SE bump might be a result of detecting a horizontal sliver feature above the main disk that could be the disk backside. Alternatively, when including the morphology of the NW side, where the disk midplane is offset in the opposite direction ~50 mas between 0farcs4 and 1farcs2, the asymmetries suggest a warp-like feature. Using our integral field spectroscopy data to search for planets, we are 50% complete for ~4 MJup planets at 4 AU. Lastly, we detect a source, resolved only along the disk plane, that could either be a candidate planetary mass companion or a compact clump in the disk.

  3. Gemini Planet Imager observations of the AU Microscopii debris disk: Asymmetries within one arcsecond

    DOE PAGES

    Wang, Jason J.; Graham, James R.; Pueyo, Laurent; Nielsen, Eric L.; Millar-Blanchaer, Max; De Rosa, Robert J.; Kalas, Paul; Ammons, S. Mark; Bulger, Joanna; Cardwell, Andrew; et al

    2015-09-23

    We present Gemini Planet Imager (GPI) observations of AU Microscopii, a young M dwarf with an edge-on, dusty debris disk. Integral field spectroscopy and broadband imaging polarimetry were obtained during the commissioning of GPI. In our broadband imaging polarimetry observations, we detect the disk only in total intensity and find asymmetries in the morphology of the disk between the southeast (SE) and northwest (NW) sides. The SE side of the disk exhibits a bump at 1'' (10 AU projected separation) that is three times more vertically extended and three times fainter in peak surface brightness than the NW side atmore » similar separations. This part of the disk is also vertically offset by 69 ± 30 mas to the northeast at 1'' when compared to the established disk midplane and is consistent with prior Atacama Large Millimeter/submillimeter Array and Hubble Space Telescope/Space Telescope Imaging Spectrograph observations. We see hints that the SE bump might be a result of detecting a horizontal sliver feature above the main disk that could be the disk backside. Alternatively, when including the morphology of the NW side, where the disk midplane is offset in the opposite direction ~50 mas between 0farcs4 and 1farcs2, the asymmetries suggest a warp-like feature. Using our integral field spectroscopy data to search for planets, we are 50% complete for ~4 MJup planets at 4 AU. Lastly, we detect a source, resolved only along the disk plane, that could either be a candidate planetary mass companion or a compact clump in the disk.« less

  4. Shocks and star formation in Stephan's Quintet. I. Gemini spectroscopy of Hα-bright knots

    SciTech Connect

    Konstantopoulos, I. S.; Cluver, M. E.; Appleton, P. N.; Guillard, P.; Trancho, G.; Bastian, N.; Charlton, J. C.; Fedotov, K.; Gallagher, S. C.; Smith, L. J.; Struck, C. J.

    2014-03-20

    We present a Gemini-GMOS spectroscopic study of Hubble Space Telescope (HST)-selected Hα-emitting regions in Stephan's Quintet (HCG 92), a nearby compact galaxy group, with the aim of disentangling the processes of shock-induced heating and star formation in its intra-group medium. The ≈40 sources are distributed across the system, but most densely concentrated in the ∼kiloparsec-long shock region. Their spectra neatly divide them into narrow- and broad-line emitters, and we decompose the latter into three or more emission peaks corresponding to spatial elements discernible in HST imaging. The emission-line ratios of the two populations of Hα-emitters confirm their nature as H II regions (90% of the sample) or molecular gas heated by a shock front propagating at ≲300 km s{sup –1}. Their redshift distribution reveals interesting three-dimensional structure with respect to gas-phase baryons, with no H II regions associated with shocked gas, no shocked regions in the intruder galaxy NGC 7318B, and a sharp boundary between shocks and star formation. We conclude that star formation is inhibited substantially, if not entirely, in the shock region. Attributing those H II regions projected against the shock to the intruder, we find a lopsided distribution of star formation in this galaxy, reminiscent of pileup regions in models of interacting galaxies. The Hα luminosities imply mass outputs, star formation rates, and efficiencies similar to nearby star-forming regions. Two large knots are an exception to this, being comparable in stellar output to the prolific 30 Doradus region. We also examine Stephan's Quintet in the context of compact galaxy group evolution, as a paradigm for intermittent star formation histories in the presence of a rich, X-ray-emitting intra-group medium. All spectra are provided as supplemental materials.

  5. Gemini North Multi-Object Spectrograph (GMOS-N) CCDs Upgrade: Project Status and Future Plans

    NASA Astrophysics Data System (ADS)

    Kleinman, Scot; Hardy, T.; Murowinski, R.; Szeto, K.; Walls, B.; Roth, K.; Chiboucas, K.; Schiavon, R.; Gimeno, G.; White, J.; Simons, D.; Rippa, M.; Labrie, K.; Dunn, J.; Hanna, K.; Cavedoni, C.; Bombino, S.

    2012-01-01

    The GMOS-N CCDs have been recently upgraded with new e2v deep-depletion devices, replacing the original EEV CCDs in use since the instrument was commissioned in late 2001. These new detectors have improved sensitivity in both the red and the blue, and were immediately used for queue observing while commissioning and detector on-sky characterization proceeded in parallel. These devices provide an incremental, yet significant upgrade which will be followed by the planned replacement of the focal plane with fully-depleted Hamamatsu red and blue sensitive devices. The interim e2v upgrade was designed to satisfy the needs of the Gemini scientific community in a timely fashion until issues encountered with the Hamamatsu CCD upgrade could be more fully addressed. Here, we present a project status update on the GMOS-N CCDs upgrade project, including details of the e2v deep-depletion CCD installation and plans for the eventual Hamamatsu upgrade. We discuss some of the complications and lessons learned during the course of the Hamamatsu project, and present the current schedule for installation of the Hamamatsu CCDs. In addition to further improved QE in the red, the Hamamatsu project will deliver faster readout times, 10% more spectral coverage, and improved detector controller software providing integrated support for nod & shuffle. By combining multiple CCDs with different anti-reflective coatings, the coming Hamamatsu focal plane array will retain the increased blue sensitivity recently realized by the e2V installation and provide an additional factor of 2 increase in QE longward of 940 nm.

  6. The Gemini NICI planet-finding campaign: the orbit of the young exoplanet β Pictoris b

    SciTech Connect

    Nielsen, Eric L.; Liu, Michael C.; Chun, Mark; Ftaclas, Christ; Wahhaj, Zahed; Biller, Beth A.; Hayward, Thomas L.; Kuchner, Marc J.; Rodigas, Timothy J.; Toomey, Douglas W.

    2014-10-20

    We present new astrometry for the young (12-21 Myr) exoplanet β Pictoris b taken with the Gemini/NICI and Magellan/MagAO instruments between 2009 and 2012. The high dynamic range of our observations allows us to measure the relative position of β Pic b with respect to its primary star with greater accuracy than previous observations. Based on a Markov Chain Monte Carlo analysis, we find the planet has an orbital semi-major axis of 9.1{sub −0.5}{sup +5.3} AU and orbital eccentricity <0.15 at 68% confidence (with 95% confidence intervals of 8.2-48 AU and 0.00-0.82 for semi-major axis and eccentricity, respectively, due to a long narrow degenerate tail between the two). We find that the planet has reached its maximum projected elongation, enabling higher precision determination of the orbital parameters than previously possible, and that the planet's projected separation is currently decreasing. With unsaturated data of the entire β Pic system (primary star, planet, and disk) obtained thanks to NICI's semi-transparent focal plane mask, we are able to tightly constrain the relative orientation of the circumstellar components. We find the orbital plane of the planet lies between the inner and outer disks: the position angle (P.A.) of nodes for the planet's orbit (211.8 ± 0.°3) is 7.4σ greater than the P.A. of the spine of the outer disk and 3.2σ less than the warped inner disk P.A., indicating the disk is not collisionally relaxed. Finally, for the first time we are able to dynamically constrain the mass of the primary star β Pic to 1.76{sub −0.17}{sup +0.18} M {sub ☉}.

  7. The Gemini NICI Planet-Finding Campaign: Deep Imaging of Stars in the Solar Neighborhood

    NASA Astrophysics Data System (ADS)

    Biller, Beth A.; Wahhaj, Z.; Liu, M.; Chun, M.; Close, L.; Ftaclas, C.; Hartung, M.; Hayward, T.; Nielsen, E.; Toomey, D.; NICI Planet-Finding Campaign Team

    2010-01-01

    The novel Near Infrared Coronagraphic Imager (NICI) on the 8-m Gemini South telescope combines a number of techniques to attenuate starlight and suppress superspeckles for direct detection of exoplanets: 1) Lyot coronagraphic imaging, 2) dual channel imaging for Spectral Differential Imaging (SDI) and 3) operation in a fixed Cassegrain rotator mode for Angular Differential Imaging (ADI). The combination of these techniques allows unprecedented contrasts of dmag > 14 (median value) at 1" in H band. We are currently conducting a 50 night planet-finding campaign using NICI. Although the majority of our survey targets are young (<300 Myr, so as to catch young planets while they are still self-luminous), we are also observing a subset of nearby stars in the immediate solar neighborhood. While these objects are old (and hence, planetary companions will be faint), they are still desirable targets for planet searches due to the excellent physical resolution possible around these stars. Additionally, their large proper motions also mean that planet candidates can be quickly confirmed. NICI is the first instrument with achieved star-planet contrasts high enough to image supergiant planets around these stars (M > 10 MJup). Here, we report on results from observations of 3 such nearby stars. At respective distances of 1.39 pc, 2.35 pc, and 3.8 pc, Proxima Centauri, Wolf 359, and Luyten's Star are the 1st, 3rd, and 22nd closest stars to the Sun. While our search yielded numerous candidate companions, especially around Proxima Centauri, all of these candidates were found to be background in second epoch observations.

  8. Spectroscopic Characterization of HD 95086 b with the Gemini Planet Imager

    NASA Astrophysics Data System (ADS)

    De Rosa, Robert J.; Rameau, Julien; Patience, Jenny; Graham, James R.; Doyon, René; Lafrenière, David; Macintosh, Bruce; Pueyo, Laurent; Rajan, Abhijith; Wang, Jason J.; Ward-Duong, Kimberly; Hung, Li-Wei; Maire, Jérôme; Nielsen, Eric L.; Ammons, S. Mark; Bulger, Joanna; Cardwell, Andrew; Chilcote, Jeffrey K.; Galvez, Ramon L.; Gerard, Benjamin L.; Goodsell, Stephen; Hartung, Markus; Hibon, Pascale; Ingraham, Patrick; Johnson-Groh, Mara; Kalas, Paul; Konopacky, Quinn M.; Marchis, Franck; Marois, Christian; Metchev, Stanimir; Morzinski, Katie M.; Oppenheimer, Rebecca; Perrin, Marshall D.; Rantakyrö, Fredrik T.; Savransky, Dmitry; Thomas, Sandrine

    2016-06-01

    We present new H (1.5-1.8 μm) photometric and K 1 (1.9-2.2 μm) spectroscopic observations of the young exoplanet HD 95086 b obtained with the Gemini Planet Imager. The H-band magnitude has been significantly improved relative to previous measurements, whereas the low-resolution K 1 (λ /δ λ ≈ 66) spectrum is featureless within the measurement uncertainties and presents a monotonically increasing pseudo-continuum consistent with a cloudy atmosphere. By combining these new measurements with literature L\\prime photometry, we compare the spectral energy distribution (SED) of the planet to other young planetary-mass companions, field brown dwarfs, and to the predictions of grids of model atmospheres. HD 95086 b is over a magnitude redder in {K}1-L\\prime color than 2MASS J12073346-3932539 b and HR 8799 c and d, despite having a similar L\\prime magnitude. Considering only the near-infrared measurements, HD 95086 b is most analogous to the brown dwarfs 2MASS J2244316+204343 and 2MASS J21481633+4003594, both of which are thought to have dusty atmospheres. Morphologically, the SED of HD 95086 b is best fit by low temperature ({T}{{eff}} = 800-1300 K), low surface gravity spectra from models which simulate high photospheric dust content. This range of effective temperatures is consistent with field L/T transition objects, but the spectral type of HD 95086 b is poorly constrained between early L and late T due to its unusual position the color-magnitude diagram, demonstrating the difficulty in spectral typing young, low surface gravity substellar objects. As one of the reddest such objects, HD 95086 b represents an important empirical benchmark against which our current understanding of the atmospheric properties of young extrasolar planets can be tested.

  9. The Gemini NICI Planet-Finding Campaign: The Offset Ring of HR 4796 A

    NASA Technical Reports Server (NTRS)

    Wahhaj, Zahed; Liu, Michael C.; Biller, Beth A.; Nielsen, Eric L.; Hayward, Thomas L.; Kuchner, Marc J.; Close, Laird M.; Chun, Mark; Ftaclas, Christ; Toomey, Douglas W.

    2014-01-01

    We present J, H, CH4 short (1.578 micrometers), CH4 long (1.652 micrometers) and K(sub s)-band images of the dust ring around the 10 Myr old star HR 4796 A obtained using the Near Infrared Coronagraphic Imager (NICI) on the Gemini-South 8.1 m Telescope. Our images clearly show for the first time the position of the star relative to its circumstellar ring thanks to NICI's translucent focal plane occulting mask. We employ a Bayesian Markov chain Monte Carlo method to constrain the offset vector between the two. The resulting probability distribution shows that the ring center is offset from the star by 16.7 +/- 1.3 milliarcseconds along a position angle of 26 +/- 3deg, along the PA of the ring, 26.47 +/- 0.04deg. We find that the size of this offset is not large enough to explain the brightness asymmetry of the ring. The ring is measured to have mostly red reflectivity across the JHKs filters, which seems to indicate micron-sized grains. Just like Neptune's 3:2 and 2:1 mean-motion resonances delineate the inner and outer edges of the classical Kuiper belt, we find that the radial extent of the HR 4796 A and the Fomalhaut rings could correspond to the 3:2 and 2:1 mean-motion resonances of hypothetical planets at 54.7 AU and 97.7 AU in the two systems, respectively. A planet orbiting HR 4796 A at 54.7 AU would have to be less massive than 1.6 Jup mass so as not to widen the ring too much by stirring.

  10. GEMINI PLANET IMAGER OBSERVATIONS OF THE AU MICROSCOPII DEBRIS DISK: ASYMMETRIES WITHIN ONE ARCSECOND

    SciTech Connect

    Wang, Jason J.; Graham, James R.; De Rosa, Robert J.; Kalas, Paul; Chiang, Eugene; Duchêne, Gaspard; Pueyo, Laurent; Chen, Christine; Greenbaum, Alexandra Z.; Nielsen, Eric L.; Millar-Blanchaer, Max; Ammons, S. Mark; Bulger, Joanna; Cardwell, Andrew; Goodsell, Stephen J.; Chilcote, Jeffrey K.; Doyon, René; Draper, Zachary H.; Esposito, Thomas M.; Fitzgerald, Michael P.; and others

    2015-10-01

    We present Gemini Planet Imager (GPI) observations of AU Microscopii, a young M dwarf with an edge-on, dusty debris disk. Integral field spectroscopy and broadband imaging polarimetry were obtained during the commissioning of GPI. In our broadband imaging polarimetry observations, we detect the disk only in total intensity and find asymmetries in the morphology of the disk between the southeast (SE) and northwest (NW) sides. The SE side of the disk exhibits a bump at 1″ (10 AU projected separation) that is three times more vertically extended and three times fainter in peak surface brightness than the NW side at similar separations. This part of the disk is also vertically offset by 69 ± 30 mas to the northeast at 1″ when compared to the established disk midplane and is consistent with prior Atacama Large Millimeter/submillimeter Array and Hubble Space Telescope/Space Telescope Imaging Spectrograph observations. We see hints that the SE bump might be a result of detecting a horizontal sliver feature above the main disk that could be the disk backside. Alternatively, when including the morphology of the NW side, where the disk midplane is offset in the opposite direction ∼50 mas between 0.″4 and 1.″2, the asymmetries suggest a warp-like feature. Using our integral field spectroscopy data to search for planets, we are 50% complete for ∼4 M{sub Jup} planets at 4 AU. We detect a source, resolved only along the disk plane, that could either be a candidate planetary mass companion or a compact clump in the disk.

  11. Disposition of [14C]methyl bromide in Fischer-344 rats after oral or intraperitoneal administration.

    PubMed

    Medinsky, M A; Bond, J A; Dutcher, J S; Birnbaum, L S

    1984-09-14

    Methyl bromide is used as a disinfectant to fumigate soil. The intent of our study was to determine the disposition of methyl bromide following a single acute administration. Male Fischer-344 rats were given 250 mumol of [14C] methyl bromide/kg body wt by either oral or i.p. administration. Urine, feces and expired air were collected and at the end of 72 h the rats were sacrificed and tissues analyzed to determine 14C excretion and tissue distribution. After i.p. administration of methyl bromide, the dominant route of excretion was exhalation of 14CO2, with 46% of the dose exhaled as 14CO2. In contrast, urinary excretion of 14C was the major route of elimination (43% of the dose) when methyl bromide was given orally. Very little of the 14C appeared in the feces (less than 3% of the dose) regardless of route of administration. In rats with bile duct cannulations, 46% of an oral dose appeared in the bile over a 24-h period. Collection of bile significantly decreased the exhalation of 14CO2 and 14C excreted in urine compared to controls. At 72 h after oral or i.p. administration, 14-17% of the 14C remained in the rats, with liver and kidney being the major organs of retention. Results indicate that route of administration can affect the pathways for excretion. In addition, excretion of 14C in bile, coupled with the low levels of radioactivity found in the feces, indicates that reabsorption of biliary metabolites from the gut plays a significant role in the disposition of [14C] methyl bromide.

  12. Reaching the Diffraction Limit - Differential Speckle and Wide-Field Imaging for the Gemini-N Telescope

    NASA Technical Reports Server (NTRS)

    Scott, Nic J.; Howell, Steve; Horch, Elliott

    2016-01-01

    Speckle imaging allows telescopes to achieve di raction limited imaging performance. The technique requires cameras capable of reading out frames at a very fast rate, e ectively `freezing out' atmospheric seeing. The resulting speckles can be correlated and images reconstructed that are at the di raction limit of the telescope. These new instruments are based on the successful performance and design of the Di erential Speckle Survey Instrument (DSSI) [2, 1]. The instruments are being built for the Gemini-N and WIYN telescopes and will be made available to the community via the peer review proposal process. We envision their primary use to be validation and characterization of exoplanet targets from the NASA K2 and TESS missions and RV discovered exoplanets. Such targets will provide excellent follow-up candidates for both the WIYN and Gemini telescopes [3]. Examples of DSSI data are shown in the gures below. We expect similar data quality in speckle imaging mode with the new instruments. Additionally, both cameras will have a wide- eld mode and standard SDSS lters. They will be highly versatile instruments and it is that likely many other science programs will request time on the cameras. The limiting magnitude for speckle observations, will remain around 13-14th at WIYN and 16-17th at Gemini, while wide- eld, normal CCD imaging operation should be able to go to much fainter, providing usual CCD imaging and photometric capabilities. The instruments will also have high utility as scoring cameras for telescope engineering purposes, or other applications where high time resolution is needed. Instrument support will be provided, including a software pipeline that takes raw speckle data to fully reconstructed images.

  13. Effect of chloramphenicol and ethidium bromide on the level of ornithine carbamoyltransferase in Neurospora crassa

    SciTech Connect

    Zerez, C.R.; Weiss, R.L.

    1986-05-01

    The specific activity of the nuclear-gene-encoded, mitochondrial arginine biosynthetic enzyme ornithine carbamoyltransferase in Neurospora crassa was elevated in mycelia treated with chloramphenicol or ethidium bromide. The increase in specific activity was caused by an increase in the number of mature enzyme molecules rather than by the activation of a preexisting enzyme. Chloramphenicol and ethidium bromide appeared to act indirectly via arginine-mediated derepression. However, derepression did not appear to result from a drug-mediated decrease in the arginine pool.

  14. Active Control of Interface Shape During the Crystal Growth of Lead Bromide

    NASA Technical Reports Server (NTRS)

    Duval, W. M. B.; Batur, C.; Singh, N. B.

    2003-01-01

    A thermal model for predicting and designing the furnace temperature profile was developed and used for the crystal growth of lead bromide. The model gives the ampoule temperature as a function of the furnace temperature, thermal conductivity, heat transfer coefficients, and ampoule dimensions as variable parameters. Crystal interface curvature was derived from the model and it was compared with the predicted curvature for a particular furnace temperature and growth parameters. Large crystals of lead bromide were grown and it was observed that interface shape was in agreement with the shape predicted by this model.

  15. Breakdown of ionic character of molecular alkali bromides in inner-valence photoionization

    SciTech Connect

    Karpenko, A. Iablonskyi, D.; Kettunen, J. A.; Cao, W.; Huttula, M.; Aksela, H.; Urpelainen, S.

    2014-05-28

    The inner-valence region of alkali bromide XBr (X=Li, Na, K, Rb) vapours has been studied experimentally by means of synchrotron radiation excited photoelectron spectroscopy. Experimental spectra were analyzed by comparing them with available theoretical results and previous experiments. Ionic character of alkali bromides is seen to change in the inner-valence region with increasing atomic number of the alkali atom. A mechanism involving mixing between Br 4s and Rb 4p orbitals has been suggested to account for the fine structure observed in inner-valence ionization region of RbBr.

  16. Disposition of [14C]methyl bromide in rats after inhalation.

    PubMed

    Bond, J A; Dutcher, J S; Medinsky, M A; Henderson, R F; Birnbaum, L S

    1985-04-01

    Methyl bromide is used as a disinfectant to fumigate soil and a wide range of stored food commodities in warehouses and mills. Human exposure occurs during the manufacture and use of the chemical. The purpose of this investigation was to determine the disposition and metabolism of [14C]methyl bromide in rats after inhalation. Male Fischer-344 rats were exposed nose only to a vapor concentration of 337 nmol [14C]methyl bromide/liter air (9.0 ppm, 25 degrees C, 620 torr) for 6 hr. Urine, feces, expired air, and tissues were collected for up to 65 hr after exposure. Elimination of 14C as 14CO2 was the major route of excretion with about 47% (3900 nmol/rat) of the total [14C]methyl bromide absorbed excreted by this route. CO2 excretion exhibited a biphasic elimination pattern with 85% of the 14CO2 being excreted with a half-time of 3.9 +/- 0.1 hr (means +/- SE) and 15% excreted with a half-time of 11.4 +/- 0.2 hr. Half-times for elimination of 14C in urine and feces were 9.6 +/- 0.1 and 16.1 +/- 0.1 hr, respectively. By 65 hr after exposure, about 75% of the initial radioactivity had been excreted with 25% remaining in the body. Radioactivity was widely distributed in tissues immediately following exposure with lung (250 nmol equivalents/g), adrenal (240 nmol equivalents/g), kidney (180 nmol equivalents/g), liver (130 nmol equivalents/g), and nasal turbinates (110 nmol equivalents/g) containing the highest concentrations of 14C. Radioactivity in livers immediately after exposure accounted for about 17% of the absorbed methyl bromide. Radioactivity in all other tissues examined accounted for about 10% of the absorbed methyl bromide. Elimination half-times of 14C from tissues were on the order of 1.5 to 8 hr. In all tissues examined, over 90% of the 14C in the tissues was methyl bromide metabolites. The data from this study indicate that after inhalation methyl bromide is rapidly metabolized in tissues and readily excreted.

  17. Bromide, Chloride, and Sulfate Concentrations, and Specific Conductance, Lake Texoma, Texas and Oklahoma, 2007-08

    USGS Publications Warehouse

    Baldys, Stanley

    2009-01-01

    The U.S. Geological Survey, in cooperation with the City of Dallas Water Utilities Division, collected water-quality data from 11 sites on Lake Texoma, a reservoir on the Texas-Oklahoma border, during April 2007-September 2008. At 10 of the sites, physical properties (depth, specific conductance, pH, temperature, dissolved oxygen, and alkalinity) were measured and samples were collected for analysis of selected dissolved constituents (bromide, calcium, magnesium, potassium, sodium, carbonate, bicarbonate, chloride, and sulfate); at one site, only physical properties were measured. The primary constituent of interest was bromide. Bromate can form when ozone is used to disinfect raw water containing bromide, and bromate is a suspected human carcinogen. Chloride and sulfate were of secondary interest. Only the analytical results for bromide, chloride, sulfate, and measured specific conductance are discussed in this report. Median dissolved bromide concentrations ranged from 0.28 to 0.60 milligrams per liter. The largest median dissolved bromide concentration (0.60 milligram per liter at site 11) was from the Red River arm of Lake Texoma. Dissolved bromide concentrations generally were larger in the Red River arm of Lake Texoma than in the Washita arm of the lake. Median dissolved chloride concentrations were largest in the Red River arm of Lake Texoma at site 11 (431 milligrams per liter) and smallest at site 8 (122 milligrams per liter) in the Washita arm. At site 11 in the Red River arm, the mean and median chloride concentrations exceeded the secondary maximum contaminant level of 300 milligrams per liter for chloride established by the 'Texas Surface Water Quality Standards' for surface-water bodies designated for the public water supply use. Median dissolved sulfate concentrations ranged from 182 milligrams per liter at site 4 in the Big Mineral arm to 246 milligrams per liter at site 11 in the Red River arm. None of the mean or median sulfate concentrations

  18. 40 CFR 180.123a - Inorganic bromide residues in peanut hay and peanut hulls; statement of policy.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Inorganic bromide residues in peanut hay and peanut hulls; statement of policy. 180.123a Section 180.123a Protection of Environment... RESIDUES IN FOOD Specific Tolerances § 180.123a Inorganic bromide residues in peanut hay and peanut...

  19. 40 CFR 180.123a - Inorganic bromide residues in peanut hay and peanut hulls; statement of policy.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Inorganic bromide residues in peanut hay and peanut hulls; statement of policy. 180.123a Section 180.123a Protection of Environment... RESIDUES IN FOOD Specific Tolerances § 180.123a Inorganic bromide residues in peanut hay and peanut...

  20. A general synthesis of fluoroalkylated alkenes by palladium-catalyzed Heck-type reaction of fluoroalkyl bromides.

    PubMed

    Feng, Zhang; Min, Qiao-Qiao; Zhao, Hai-Yang; Gu, Ji-Wei; Zhang, Xingang

    2015-01-19

    An efficient palladium-catalyzed Heck-type reaction of fluoroalkyl halides, including perfluoroalkyl bromides, trifluoromethyl iodides, and difluoroalkyl bromides, has been developed. The reaction proceeds under mild reaction conditions with high efficiency and broad substrate scope, and provides a general and straightforward access to fluoroalkylated alkenes which are of interest in life and material sciences.