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Sample records for all-carbon quaternary center

  1. Dual-face nucleoside scaffold featuring a stereogenic all-carbon quaternary center. Intramolecular silicon tethered group-transfer reaction.

    PubMed

    Tambutet, Guillaume; Becerril-Jiménez, Fabiola; Dostie, Starr; Simard, Ryan; Prévost, Michel; Mochirian, Philippe; Guindon, Yvan

    2014-11-01

    The design of a novel nucleoside scaffold that exhibits an all-carbon quaternary center is reported. This allows for both α- and β-anomers of a given 2'-deoxy-2',2'-difluoro nucleoside analog (NA) to have potential biological activity. Using an intramolecular atom-transfer reaction, an all-carbon quaternary center was obtained without the use of heavy metals and/or harsh conditions. The chemistry developed is efficient, easily scalable and leads to novel libraries of molecules.

  2. Inter- and intramolecular annulation strategies to a cyclopentanone building block containing an all-carbon quaternary stereogenic center.

    PubMed

    Penrose, Stephen D; Stott, Andrew J; Breccia, Perla; Haughan, Alan F; Bürli, Roland W; Jarvis, Rebecca E; Dominguez, Celia

    2015-03-20

    Synthesis of (S)-2-methyl-3-fluorophenyl cyclopentanone methyl ester (1S)-1 has been achieved by both inter- and intramolecular alkylation reactions on multigram scale, using chiral pool reagents. The intramolecular variant is a novel example of a chiral bis-electrophile reacting with a carbon nucleophile to form an enantiomerically pure all-carbon quaternary center. PMID:25720587

  3. Tunable Phosphoramidite Ligands for Asymmetric Hydrovinylation: Ligands par excellence for Generation of All-Carbon Quaternary Centers

    PubMed Central

    Smith, Craig R.; Lim, Hwan Jung; Zhang, Aibin; RajanBabu, T. V.

    2009-01-01

    1-Alkylstyrenes undergo efficient hydrovinylation (addition of ethylene) in the presence of a Ni-catalyst prepared from [(allyl)NiBr]2, Na+ [BAr4]− (Ar = 3,5-bis-trifluromethylphenyl), and a phosphoramidite ligand giving products in excellent yields and enantioselectivities. In many cases phosphoramidites derived from achiral 2,2′-biphenol are almost as good as ligands derived from the more expensive enantiopure 2,2′-binaphthols. The hydrovinylation products, which carry two versatile latent functionalities, an aryl and a vinyl group, are potentially useful for the synthesis of several important natural products containing benzylic all-carbon quaternary centers. PMID:19763244

  4. All-carbon quaternary stereogenic centers in acyclic systems through the creation of several C-C bonds per chemical step.

    PubMed

    Marek, Ilan; Minko, Yury; Pasco, Morgane; Mejuch, Tom; Gilboa, Noga; Chechik, Helena; Das, Jaya P

    2014-02-19

    In the past few decades, it has become clear that asymmetric catalysis is one of the most powerful methods for the construction of carbon-carbon as well as carbon-heteroatom bonds in a stereoselective manner. However, when structural complexity increases (i.e., all-carbon quaternary stereogenic center), the difficulty in reaching the desired adducts through asymmetric catalytic reactions leads to a single carbon-carbon bond-forming event per chemical step between two components. Issues of efficiency and convergence should therefore be addressed to avoid extraneous chemical steps. In this Perspective, we present approaches that tackle the stimulating problem of efficiency while answering interesting synthetic challenges. Ideally, if one could create all-carbon quaternary stereogenic centers via the creation of several new carbon-carbon bonds in an acyclic system and in a single-pot operation from simple precursors, it would certainly open new horizons toward solving the synthetic problems. Even more important for any further design, the presence of polyreactive intermediates in synthesis (bismetalated, carbenoid, and oxenoids species) becomes now an indispensable tool, as it creates consecutively the same number of carbon-carbon bonds as in a multi-step process, but in a single-pot operation.

  5. Diphenylprolinol silyl ether catalyzed asymmetric Michael reaction of nitroalkanes and β,β-disubstituted α,β-unsaturated aldehydes for the construction of all-carbon quaternary stereogenic centers.

    PubMed

    Hayashi, Yujiro; Kawamoto, Yuya; Honda, Masaki; Okamura, Daichi; Umemiya, Shigenobu; Noguchi, Yuka; Mukaiyama, Takasuke; Sato, Itaru

    2014-09-15

    The asymmetric Michael reaction of nitroalkanes and β,β-disubstituted α,β-unsaturated aldehydes was catalyzed by diphenylprolinol silyl ether to afford 1,4-addition products with an all-carbon quaternary stereogenic center with excellent enantioselectivity. The reaction is general for β-substituents such as β-aryl and β-alkyl groups, and both nitromethane and nitroethane can be employed. The addition of nitroethane is considered a synthetic equivalent of the asymmetric Michael reaction of ethyl and acetyl substituents by means of radical denitration and Nef reaction, respectively. The short asymmetric synthesis of (S)-ethosuximide with a quaternary carbon center was accomplished by using the present asymmetric Michael reaction as the key step. The reaction mechanism that involves the E/Z isomerization of α,β-unsaturated aldehydes, the retro-Michael reaction, and the different reactivity between nitromethane and nitroethane is discussed.

  6. Stereospecific Cross Couplings To Set Benzylic, All-Carbon Quaternary Stereocenters in High Enantiopurity.

    PubMed

    Zhou, Qi; Cobb, Kelsey M; Tan, Tianyu; Watson, Mary P

    2016-09-21

    Asymmetric preparation of all-carbon quaternary stereocenters is an important goal. Despite advances in formation of highly enantioenriched products with quaternary stereocenters proximal to a functional group, methods to install quaternary stereocenters isolated from functional groups are limited. Transition metal catalysis offers a potential solution, but prior cross couplings are limited to allylic substrates or deliver little to no enantiomeric enrichment. We report a stereospecific, nickel-catalyzed Suzuki-Miyaura arylation of tertiary benzylic acetates to deliver products with diaryl and triaryl quaternary stereocenters in high yields and ee's. This reaction employs an inexpensive, air-stable Ni(II) salt and commercially available phosphine ligand to transform tertiary alcohol derivatives, which are easily available in exceptional ee, into valuable products with stereoretention. PMID:27610831

  7. Recent Developments in the Catalytic, Asymmetric Construction of Pyrroloindolines Bearing All-Carbon Quaternary Stereocenters

    PubMed Central

    Repka, Lindsay M.; Reisman, Sarah E.

    2014-01-01

    Pyrroloindoline alkaloids constitute a large family of natural products that has inspired the development of an impressive array of new reactions to prepare the key heterocyclic motif. This synopsis will address catalytic, asymmetric reactions developed to synthesize pyrroloindolines bearing C3a all-carbon quaternary stereocenters. The methods described herein include both transition metal-catalyzed and organocatalyzed reactions that have been demonstrated suitable for the synthesis of the pyrroloindoline framework. PMID:24295135

  8. Palladium-catalysed formation of vicinal all-carbon quaternary centres via propargylation

    PubMed Central

    Huang, Xin; Wu, Shangze; Wu, Wangteng; Li, Pengbin; Fu, Chunling; Ma, Shengming

    2016-01-01

    Construction of two vicinal all-carbon quaternary carbon centres is of great importance due to the common presence of such units in natural and unnatural molecules with attractive functions. However, it remains a significant challenge. Here, we have developed a palladium-catalysed general coupling for the efficient connection of two tertiary carbon atoms: Specifically, propargylic carbonate has been treated with a fully loaded soft functionalized nucleophile to connect such two fully loaded carbon atoms with a simple palladium catalyst. It is observed that the central chirality in the optically active tertiary propargylic carbonates has been remembered and transferred into the products with very high efficiency. The triple bond and the functional groups such as ester, cyano and unsaturated C–C bonds make this method a relatively general solution for such a purpose due to their high synthetic versatility. PMID:27558203

  9. Palladium-catalysed formation of vicinal all-carbon quaternary centres via propargylation

    NASA Astrophysics Data System (ADS)

    Huang, Xin; Wu, Shangze; Wu, Wangteng; Li, Pengbin; Fu, Chunling; Ma, Shengming

    2016-08-01

    Construction of two vicinal all-carbon quaternary carbon centres is of great importance due to the common presence of such units in natural and unnatural molecules with attractive functions. However, it remains a significant challenge. Here, we have developed a palladium-catalysed general coupling for the efficient connection of two tertiary carbon atoms: Specifically, propargylic carbonate has been treated with a fully loaded soft functionalized nucleophile to connect such two fully loaded carbon atoms with a simple palladium catalyst. It is observed that the central chirality in the optically active tertiary propargylic carbonates has been remembered and transferred into the products with very high efficiency. The triple bond and the functional groups such as ester, cyano and unsaturated C-C bonds make this method a relatively general solution for such a purpose due to their high synthetic versatility.

  10. Palladium-catalysed formation of vicinal all-carbon quaternary centres via propargylation.

    PubMed

    Huang, Xin; Wu, Shangze; Wu, Wangteng; Li, Pengbin; Fu, Chunling; Ma, Shengming

    2016-01-01

    Construction of two vicinal all-carbon quaternary carbon centres is of great importance due to the common presence of such units in natural and unnatural molecules with attractive functions. However, it remains a significant challenge. Here, we have developed a palladium-catalysed general coupling for the efficient connection of two tertiary carbon atoms: Specifically, propargylic carbonate has been treated with a fully loaded soft functionalized nucleophile to connect such two fully loaded carbon atoms with a simple palladium catalyst. It is observed that the central chirality in the optically active tertiary propargylic carbonates has been remembered and transferred into the products with very high efficiency. The triple bond and the functional groups such as ester, cyano and unsaturated C-C bonds make this method a relatively general solution for such a purpose due to their high synthetic versatility. PMID:27558203

  11. The Construction of All-Carbon Quaternary Stereocenters by Use of Pd-Catalyzed Asymmetric Allylic Alkylation Reactions in Total Synthesis

    PubMed Central

    Hong, Allen Y.

    2014-01-01

    All-carbon quaternary stereocenters have posed significant challenges in the synthesis of complex natural products. These important structural motifs have inspired the development of broadly applicable palladium-catalyzed asymmetric allylic alkylation reactions of unstabilized non-biased enolates for the synthesis of enantioenriched α-quaternary products. This microreview outlines key considerations in the application of palladium-catalyzed asymmetric allylic alkylation reactions and presents recent total syntheses of complex natural products that have employed these powerful transformations for the direct, catalytic, enantioselective construction of all-carbon quaternary stereocenters. PMID:24944521

  12. Asymmetric Assembly of All-Carbon Tertiary/Quaternary Nonadjacent Stereocenters through Organocatalytic Conjugate Addition of α-Cyanoacetates to a Methacrylate Equivalent.

    PubMed

    Iriarte, Igor; Vera, Silvia; Badiola, Eider; Mielgo, Antonia; Oiarbide, Mikel; García, Jesús M; Odriozola, José M; Palomo, Claudio

    2016-09-12

    An efficient, highly diastereo- and enantioselective assembly of acyclic carbonyl fragments possessing nonadjacent all-carbon tertiary/quaternary stereoarrays is reported based on a Brønsted base catalyzed Michael addition/α-protonation sequence involving α-cyanoacetates and 2,4-dimethyl-4-hydroxypenten-3-one as novel methacrylate equivalent. PMID:27487331

  13. Formation of quaternary stereogenic centers by copper-catalyzed asymmetric conjugate addition reactions of alkenylaluminums to trisubstituted enones.

    PubMed

    Müller, Daniel; Alexakis, Alexandre

    2013-11-01

    Alkenylaluminums undergo asymmetric copper-catalyzed conjugate addition (ACA) to β-substituted enones allowing the formation of stereogenic all-carbon quaternary centers. Phosphinamine-copper complexes proved to be particularly active and selective compared with phosphoramidite ligands. After extensive optimization, high enantioselectivities (up to 96% ee) were obtained for the addition of alkenylalanes to β-substituted enones. Two strategies for the generation of the requisite alkenylaluminums were explored allowing for the introduction of aryl- and alkyl-substituted alkenyl nucleophiles. Moreover, alkyl-substituted phosphinamine (SimplePhos) ligands were identified for the first time as highly efficient ligands for the Cu-catalyzed ACA.

  14. Domino Michael-Michael and Aldol-Aldol Reactions: Diastereoselective Synthesis of Functionalized Cyclohexanone Derivatives Containing Quaternary Carbon Center.

    PubMed

    Ghorai, Manas K; Halder, Sandipan; Das, Subhomoy

    2015-10-01

    A simple strategy for the synthesis of highly functionalized cyclohexanone derivatives containing an all-carbon quaternary center from α-(aryl/alkyl)methylidene-β-keto esters or β-diketones via a K-enolate mediated domino Michael-Michael reaction sequence with moderate to good yield and excellent diastereoselectivity (de > 99%) is described. Interestingly, Li-base mediated reaction of α-arylmethylidene-β-diketones affords functionalized 3,5-dihydroxy cyclohexane derivatives as the kinetically controlled products via a domino aldol-aldol reaction sequence with excellent diastereoselectivity. Li-enolates of the β-keto esters or β-diketones undergo facile domino Michael-Michael reaction with nitro-olefins to afford the corresponding nitrocyclohexane derivatives in good yields and excellent diastereoselectivity (de > 99%). The formation of the products and the observed stereoselectivity were explained by plausible mechanisms and supported by extensive computational study. An asymmetric version of the protocol was explored with (L)-menthol derived nonracemic substrates, and the corresponding nonracemic cyclohexanone derivatives containing an all-carbon quaternary center were obtained with excellent stereoselectivity (de, ee > 99%).

  15. Copper-catalyzed propargylic substitution of dichloro substrates: enantioselective synthesis of trisubstituted allenes and formation of propargylic quaternary stereogenic centers.

    PubMed

    Li, Hailing; Grassi, David; Guénée, Laure; Bürgi, Thomas; Alexakis, Alexandre

    2014-12-01

    An easy and versatile Cu-catalyzed propargylic substitution process is presented. Using easily prepared prochiral dichloro substrates, readily available Grignard reagents together with catalytic amount of copper salt and chiral ligand, we accessed a range of synthetically interesting trisubstituted chloroallenes. Substrate scope and nucleophile scope are broad, providing generally high enantioselectivity for the desired 1,3-substitution products. The enantioenriched chloroallenes could be further transformed into the corresponding trisubstituted allenes or terminal alkynes bearing all-carbon quaternary stereogenic centers, through the copper-catalyzed enantiospecific 1,1/1,3-substitutions. The two successive copper-catalyzed reactions could be eventually combined into a one-pot procedure and different desired allenes or alkynes were obtained respectively with high enantiomeric excesses. PMID:25327947

  16. Ethylene in Organic Synthesis. A New Route to Anticholenergic Pyrrolidinoindolines, and Other Molecules with All Carbon-Quaternary Centers via Asymmetric Hydrovinylation

    PubMed Central

    Lim, Hwan Jung; RajanBabu, T. V.

    2011-01-01

    The asymmetric hydrovinylation (1 mol % Ni-cat., 1 atm, ethylene, >98% ee) products from 1-methylenetetralines are readily converted into 3,3-disubstituted oxindoles, and subsequently to pyrrolidinoindolines. These hydrovinylation products are also useful for the syntheses of enantiopure benzomorphans. PMID:22103775

  17. Visible Light-Induced Photoredox Construction of Trifluoromethylated Quaternary Carbon Centers from Trifluoromethylated Tertiary Bromides.

    PubMed

    Huan, Feng; Chen, Qing-Yun; Guo, Yong

    2016-08-19

    A mild, operationally simple, visible light-induced photoredox method for constructing novel trifluoromethylated quaternary carbon centers from trifluoromethylated tertiary bromides has been developed. Using this method, a wide range of alkenes were successfully bifunctionalized to γ-butyrolactams. As for electron-rich alkenes, reactions catalyzed by Ir(dF(CF3)ppy)2(dtbbpy)(PF6) were kinetic processes with high yields and short times. For styrenes, reactions catalyzed by Ir(ppy)2(dtbbpy)(PF6) were thermodynamic processes with moderate yields and prolonged reaction times. For aliphatic alkenes, the reactions were neither thermodynamic nor kinetic and fac-Ir(ppy)3 was used as catalyst. Thus, reactions were not as efficient as electron-rich alkenes. The atom-transfer radical addition reactions of trifluoromethylated tertiary bromides with alkynes were also achieved. The configuration of products we separated was E type only. Some of the products exhibited bactericidal activity.

  18. Visible Light-Induced Photoredox Construction of Trifluoromethylated Quaternary Carbon Centers from Trifluoromethylated Tertiary Bromides.

    PubMed

    Huan, Feng; Chen, Qing-Yun; Guo, Yong

    2016-08-19

    A mild, operationally simple, visible light-induced photoredox method for constructing novel trifluoromethylated quaternary carbon centers from trifluoromethylated tertiary bromides has been developed. Using this method, a wide range of alkenes were successfully bifunctionalized to γ-butyrolactams. As for electron-rich alkenes, reactions catalyzed by Ir(dF(CF3)ppy)2(dtbbpy)(PF6) were kinetic processes with high yields and short times. For styrenes, reactions catalyzed by Ir(ppy)2(dtbbpy)(PF6) were thermodynamic processes with moderate yields and prolonged reaction times. For aliphatic alkenes, the reactions were neither thermodynamic nor kinetic and fac-Ir(ppy)3 was used as catalyst. Thus, reactions were not as efficient as electron-rich alkenes. The atom-transfer radical addition reactions of trifluoromethylated tertiary bromides with alkynes were also achieved. The configuration of products we separated was E type only. Some of the products exhibited bactericidal activity. PMID:27438228

  19. Sr and Nd isotopic and trace element compositions of Quaternary volcanic centers of the Southern Andes

    USGS Publications Warehouse

    Futa, K.; Stern, C.R.

    1988-01-01

    Isotopic compositions of samples from six Quaternary volcanoes located in the northern and southern extremities of the Southern Volcanic Zone (SVZ, 33-46??S) of the Andes and from four centers in the Austral Volcanic Zone (AVZ, 49-54??S) range for 87Sr 86Sr from 0.70280 to 0.70591 and for 143Nd 144Nd from 0.51314 to 0.51255. The ranges are significantly greater than previously reported from the southern Andes but are different from the isotopic compositions of volcanoes in the central and northern Andes. Basalts and basaltic andesites from three centers just north of the Chile Rise-Trench triple junction have 87Sr 86Sr, 143Nd 144Nd, La Yb, Ba La, and Hf Lu that lie within the relatively restricted ranges of the basic magmas erupted from the volcanic centers as far north as 35??S in the SVZ of the Andes. The trace element and Sr and Nd isotopic characteristics of these magmas may be explained by source region contamination of subarc asthenosphere, with contaminants derived from subducted pelagic sediments and seawater-altered basalts by dehydration of subducted oceanic lithosphere. In the northern extremity of the SVZ between 33?? and 34??S, basaltic andesites and andesites have higher 87Sr 86Sr, Rb Cs, and Hf Lu, and lower 143Nd 144Nd than basalts and basaltic andesites erupted farther south in the SVZ, which suggests involvement of components derived from the continental crust. In the AVZ, the most primitive sample, high-Mg andesite from the southernmost volcanic center in the Andes (54??S) has Sr and Nd isotopic compositions and K Rb and Ba La similar to MORB. The high La Yb of this sample suggests formation by small degrees of partial melting of subducted MORB with garnet as a residue. Samples from centers farther north in the AVZ show a regionally regular northward increase in SiO2, K2O, Rb, Ba, Ba La, and 87Sr 86Sr and decrease in MgO, Sr, K Rb, Rb Cs, and 143Nd 144Nd, suggesting increasingly greater degrees of fractional crystallization and associated intra

  20. Enantioselective Construction of Remote Quaternary Stereocenters

    PubMed Central

    Mei, Tian-Sheng; Patel, Harshkumar H.; Sigman, Matthew S.

    2014-01-01

    Summary Molecules containing all-carbon quaternary stereocenters – carbon atoms bonded to four distinct carbon substituents – are prevalent in Nature. However, the construction of such compounds in an enantioselective fashion remains a long-standing challenge to synthetic organic chemists. In particular, methods for forging quaternary stereocenters that are remote from other functional groups are underdeveloped. Herein we report a catalytic and enantioselective intermolecular Heck-type reaction of trisubstituted-alkenyl alcohols with aryl boronic acids. The reported method allows direct access to quaternary all-carbon-substituted β-, γ-, δ-, ε- or ζ aryl carbonyl compounds, as the unsaturation of the alkene is relayed to the alcohol resulting in the formation of a carbonyl group. The scope of the process also includes incorporation of pre-existing stereocenters along the alkyl chain, which links the alkene and the alcohol, wherein the stereocenter is preserved. The described method is flexible, allowing access to diverse building blocks containing an enantiomerically enriched, quaternary center. PMID:24717439

  1. Sterically Demanding Unsymmetrical Diaryl-λ3-iodanes for Electrophilic Pentafluorophenylation and an Approach to α-Pentafluorophenyl Carbonyl Compounds with an All-Carbon Stereocenter

    PubMed Central

    Matsuzaki, Kohei; Okuyama, Kenta; Tokunaga, Etsuko; Shiro, Motoo; Shibata, Norio

    2014-01-01

    A sterically demanding unsymmetrical pentafluorophenyl-triisopropylphenyl-λ3-iodane was developed as an effective reagent for the electrophilic pentafluorophenylation of various β-keto esters and a β-keto amide. 17 examples of α-pentafluorophenylated 1,3-dicarbonyl compounds 3 having a quaternary carbon center are provided. The resulting compounds were nicely transformed into chiral α-pentafluorophenyl ketones with an all-carbon stereogenic center in high yields and high enantioselectivities using asymmetric organocatalysis (up to 98 % ee) or asymmetric metal catalysis (up to 82 % ee). PMID:25558441

  2. [Climate implications of terrestrial paleoclimate]. Quaternary Sciences Center, Desert Research Institute annual report, fiscal year 1994/1995

    SciTech Connect

    Wigand, P.E.

    1995-12-31

    The objective of this study is to collect terrestrial climate indicators for paleoclimate synthesis. The paleobiotic and geomorphic records are being examined for the local and regional impact of past climates to assess Yucca Mountain`s suitability as a high-level nuclear waste repository. In particular these data are being used to provide estimates of the timing, duration and extremes of past periods of moister climate for use in hydrological models of local and regional recharge that are being formulated by USGS and other hydrologists for the Yucca Mountain area. The project includes botanical, faunal, and geomorphic components that will be integrated to accomplish this goal. To this end personnel at the Quaternary Sciences Center of the Desert Research Institute in Reno, Nevada are conducting the following activities: Analyses of packrat middens; Analysis of pollen samples; and Determination of vegetation climate relationships.

  3. Transition-Metal-Free Cyclopropanation of 2-Aminoacrylates with N-Tosylhydrazones: A General Route to Cyclopropane α-Amino Acid with Contiguous Quaternary Carbon Centers.

    PubMed

    Zhu, Chuanle; Li, Jiawei; Chen, Pengquan; Wu, Wanqing; Ren, Yanwei; Jiang, Huanfeng

    2016-03-18

    Cyclopropanation of 2-aminoacrylates with N-tosylhydrazones could proceed smoothly under transition-metal-free conditions via a [3 + 2] cycloaddition process. This robust protocol exhibits excellent generality, delivering a wide spectrum of cyclopropane α-amino acid esters bearing contiguous quaternary carbon centers in high yields and diastereoselectivities. With these readily available products, the steric convergence of cyclopropane α-amino acids could be readily obtained.

  4. Late Quaternary geology of small basaltic volcanic centers, SW USA: Disparity among dating methods and implications for volcanic and geomorphic studies

    SciTech Connect

    Wells, S.; McFadden, L.; Perry, F.; Forman, S.; Crowe, B.; Pothis, J.; Olinger, C.

    1992-12-31

    Evaluation of volcanic hazards near the proposed high-level radioactive waste repository at Yucca Mountain provides the impetus for a series of detailed field and geochronologic studies of selected small late Quaternary basaltic scoria cones and lava flows in Nevada and California. Two of the most significant results of these studies are: the presence of chronostratigraphic units which indicate multiple eruptions with significant intervals of no activity between events (polycyclic volcanism); and a marked difference between conventional, numerical ages derived from K-Ar and Ar-40/Ar-39 methods and numerical, calibrated, and relative ages derived from thermoluminescence, cosmogenic He-3, the degree of soil development, and geomorphology of these volcanic landforms. Soil-bounded unconformities and buried stone pavements define the boundaries of chronostratigraphic units within these small volume basaltic centers. Volcanic centers displaying this type of stratigraphy may appear morphological simple but cannot be considered mongenetic. Recent studies by Perry and Crowe demonstrate that geochemical variations within a single basaltic volcanic center in NV are consistent with several magma batches forming a complex polycyclic volcano. The K-Ar and Ar-40/Ar-39 ages are 1--2 orders of magnitude older than either TL or cosmogenic He-3 and appear to have insufficient precision to constrain the ages of chronostratigraphic units within polycyclic volcanoes. In contrast, preliminary data indicate the TL and cosmogenic He-3 dating methods have the ability to resolve the late Quaternary volcanic stratigraphy, and results from these dating methods are consistent with the degree of soil development and geomorphic modification of the volcanic units. K-Ar and Ar-40/Ar-39 dates from these small basaltic volcanic centers have been used to calibrate new Quaternary dating methods, e.g. rock varnish, which in turn have been used to interpret landscape evolution in the SW US.

  5. Asymmetric Desymmetrization via Metal-Free C-F Bond Activation: Synthesis of 3,5-Diaryl-5-fluoromethyloxazolidin-2-ones with Quaternary Carbon Centers.

    PubMed

    Tanaka, Junki; Suzuki, Satoru; Tokunaga, Etsuko; Haufe, Günter; Shibata, Norio

    2016-08-01

    We disclose the first asymmetric activation of a non-activated aliphatic C-F bond in which a conceptually new desymmetrization of 1,3-difluorides by silicon-induced selective C-F bond scission is a key step. The combination of a cinchona alkaloid based chiral ammonium bifluoride catalyst and N,O-bis(trimethylsilyl)acetoamide (BSA) as the silicon reagent enabled the efficient catalytic cycle of asymmetric Csp3 -F bond cleavage under mild conditions with high enantioselectivities. The ortho effect of the aryl group at the prostereogenic center is remarkable. This concept was applied for the asymmetric synthesis of promising agrochemical compounds, 3,5-diaryl-5-fluoromethyloxazolidin-2-ones bearing a quaternary carbon center.

  6. Quaternary investigation

    SciTech Connect

    Stieve, A.

    1991-05-15

    The primary purpose of the Quaternary investigation is to provide information on the location and age of Quaternary deposits for use in evaluating the presence or absence of neotectonic deformation or paleoliquefaction features within the Savannah River Site (SRS) region. The investigation will provide a basis for evaluating the potential for capable faults and associated deformation in the SRS vicinity. Particular attention will be paid to the Pen Branch fault.

  7. Accelerating late Quaternary uplift of the New Georgia Island Group (Solomon island arc) in response to subduction of the recently active Woodlark spreading center and Coleman seamount

    NASA Astrophysics Data System (ADS)

    Mann, Paul; Taylor, Frederick W.; Lagoe, Martin B.; Quarles, Andrew; Burr, G.

    1998-10-01

    The New Georgia Island Group of the Solomon Islands is one of four places where an active or recently active spreading ridge has subducted beneath an island arc. We have used coral reef terraces, paleobathymetry of Neogene sedimentary rocks, and existing marine geophysical data to constrain patterns of regional Quaternary deformation related to subduction of the recently active Woodlark spreading center and its overlying Coleman seamount. These combined data indicate the following vertical tectonic history for the central part of the New Georgia Island Group: (1) subsidence of the forearc region (Tetepare and Rendova Islands) to water depths of ˜1500 m and deposition of marine turbidites until after 270 ka; (2) late Quaternary uplift of the forearc to sea level and erosion of an unconformity; (3) subsidence of the forearc to ˜500 m BSL and deposition of bathyal sediments; and (4) uplift of the forearc above sea level with Holocene uplift rates up to at least 7.5 mm/yr on Tetepare and 5 mm/yr on Rendova. In the northeastern part of the New Georgia Island Group, our combined data indicate a slightly different tectonic history characterized by lower-amplitude vertical motions and a more recent change from subsidence to uplift. Barrier reefs formed around New Georgia and Vangunu Islands as they subsided >300 m. By 50-100 ka, subsidence was replaced by uplift that accelerated to Holocene rates of ˜1 mm/yr on the volcanic arc compared with rates up to ˜7.5 mm/yr in the forearc area of Tetepare and Rendova. Uplift mechanisms, such as thermal effects due to subduction of spreading ridges, tectonic erosion, or underplating of deeply subducted bathymetric features, are not likely to function on the 270-ka period that these uplift events have occurred in the New Georgia Island Group. A more likely uplift mechanism for the post-270-ka accelerating uplift of the forearc and volcanic arc of the New Georgia Island Group is progressive impingement of the Coleman seamount or

  8. Hydrogeologic framework and ground-water Flow in quaternary deposits at the U.S. Army Atterbury Joint Maneuver Training Center near Edinburgh, Indiana, 2002-2003

    USGS Publications Warehouse

    Robinson, Bret A.; Risch, Martin R.

    2006-01-01

    A hydrogeologic framework was developed for unconsolidated Quaternary deposits at the U.S. Army Atterbury Joint Maneuver Training Center. The framework describes the potential for the occurrence of ground water on the basis of physiography and the distribution of geologic materials within the study area. Four geologic units-the Jessup, Trafalgar, Atherton, and Martinsville Formations-were identified, and their distribution was mapped as four hydrogeologic regions. The Jessup and Trafalgar Formations are fine-grained, poorly sorted tills. At least two facies of the Atherton Formation, the lacustrine and outwash facies, are in the study area. The Martinsville Formation includes materials deposited or reworked since the glacial period. With the exception of the Atherton Formation outwash facies, the Quaternary deposits are primarily fine-grained, silt- and clay-rich sediments that function as confining layers or aquitards. The Atherton Formation out-wash facies includes sand and gravel deposits that constitute the primary aquifers in the study area. The four hydrogeologic regions mapped in this investigation are designated as the Bedrock, Jessup Till, Trafalgar Till, and Atherton Outwash Regions. Each region represents an area with a distinctive physiographic expression and vertical sequence of Quaternary deposits. The Bedrock Region in the western and southwestern part of the study area commonly is underlain by 0 to 15 feet of Martinsville Formation resting directly on bedrock. Potential ground-water yields are limited. The Jessup Till Region in the southeastern part of the study area includes the uplands on either side of the stream valleys. Sediments commonly range from 30 to 90 feet in thickness. This region includes clay-rich till of the Jessup Formation and sand and gravel deposits of the Atherton Formation outwash facies; the Atherton Formation outwash facies tends to be thin, and ground-water yields will be moderate. The Trafalgar Till Region in the north and

  9. Quaternary and Geomorphology.

    ERIC Educational Resources Information Center

    Andrews, J. T.; Graf, W. L.

    1983-01-01

    Highlights conferences and meetings of organizations involved with quaternary geology and geomorphology, including International Union of Quaternary Research Conference held in Moscow. The impetus of a revision of "The Quaternary of the United States" resulted from this conference. Includes activities/aims of "Friends of the Pleistocene"…

  10. Flexible all-carbon photovoltaics with improved thermal stability

    SciTech Connect

    Tang, Chun; Ishihara, Hidetaka; Sodhi, Jaskiranjeet; Chen, Yen-Chang; Siordia, Andrew; Martini, Ashlie; Tung, Vincent C.

    2015-04-15

    The structurally robust nature of nanocarbon allotropes, e.g., semiconducting single-walled carbon nanotubes (SWCNTs) and C{sub 60}s, makes them tantalizing candidates for thermally stable and mechanically flexible photovoltaic applications. However, C{sub 60}s rapidly dissociate away from the basal of SWCNTs under thermal stimuli as a result of weak intermolecular forces that “lock up” the binary assemblies. Here, we explore use of graphene nanoribbons (GNRs) as geometrically tailored protecting layers to suppress the unwanted dissociation of C{sub 60}s. The underlying mechanisms are explained using a combination of molecular dynamics simulations and transition state theory, revealing the temperature dependent disassociation of C{sub 60}s from the SWCNT basal plane. Our strategy provides fundamental guidelines for integrating all-carbon based nano-p/n junctions with optimized structural and thermal stability. External quantum efficiency and output current–voltage characteristics are used to experimentally quantify the effectiveness of GNR membranes under high temperature annealing. Further, the resulting C{sub 60}:SWCNT:GNR ternary composites display excellent mechanical stability, even after iterative bending tests. - Graphical abstract: The incorporation of solvent resistant, mechanically flexible and electrically addressable 2-D soft graphene nanoribbons facilitates the assembly of photoconductive carbon nano-p/n junctions for thermally stable and flexible photovoltaic cells.

  11. Flexible all-carbon photovoltaics with improved thermal stability

    NASA Astrophysics Data System (ADS)

    Tang, Chun; Ishihara, Hidetaka; Sodhi, Jaskiranjeet; Chen, Yen-Chang; Siordia, Andrew; Martini, Ashlie; Tung, Vincent C.

    2015-04-01

    The structurally robust nature of nanocarbon allotropes, e.g., semiconducting single-walled carbon nanotubes (SWCNTs) and C60s, makes them tantalizing candidates for thermally stable and mechanically flexible photovoltaic applications. However, C60s rapidly dissociate away from the basal of SWCNTs under thermal stimuli as a result of weak intermolecular forces that "lock up" the binary assemblies. Here, we explore use of graphene nanoribbons (GNRs) as geometrically tailored protecting layers to suppress the unwanted dissociation of C60s. The underlying mechanisms are explained using a combination of molecular dynamics simulations and transition state theory, revealing the temperature dependent disassociation of C60s from the SWCNT basal plane. Our strategy provides fundamental guidelines for integrating all-carbon based nano-p/n junctions with optimized structural and thermal stability. External quantum efficiency and output current-voltage characteristics are used to experimentally quantify the effectiveness of GNR membranes under high temperature annealing. Further, the resulting C60:SWCNT:GNR ternary composites display excellent mechanical stability, even after iterative bending tests.

  12. Attempts to prepare an all-carbon indigoid system

    PubMed Central

    Yildizhan, Şeref; Jones, Peter G

    2015-01-01

    Summary First attempts are described to prepare a precursor for an all-carbon analog of indigo, the tetracyclic triene 4. Starting from indan-2-one (9) the α-methylene ketone 13 was prepared. Upon subjecting this compound to a McMurry coupling reaction, it dimerized to the bis-indene derivative 17, rather than providing the tetramethyl derivative of 4, the hydrocarbon 14. In a second approach, indan-1-one (18) was dimerized to the conjugated enedione 21 through the bis-1-indene dimer 19. All attempts to methylenate 21 failed, however. When 19 was treated with the Tebbe reagent, the dimer 23 was produced, presumably through a Cope reaction of the intermediately generated isomer 22. The bis-indene derivative 23 can be alkylated with 1,2-dibromoethane to produce a 1:1 mixture of the spiro compounds 24 and 25. Although 9 could be reductively dimerized to 30, the conversion of this olefin to 14 failed. PMID:25977710

  13. Site- and Enantioselective Formation of Allene-Bearing Tertiary or Quaternary Carbon Stereogenic Centers through NHC–Cu-Catalyzed Allylic Substitution

    PubMed Central

    Jung, Byunghyuck; Hoveyda, Amir H.

    2012-01-01

    Catalytic enantioselective allylic substitutions that result in exclusive addition of an allenyl group (<2% propargyl addition) and formation of tertiary or quaternary C–C bonds are described. Commercially available allenylboronic acid pinacol ester is used (preparation of a more reactive but less stable boronate derivative not required). Reactions are promoted by 5.0–10 mol % of sulfonate-bearing chiral bidentate N-heterocyclic carbene (NHC) complexes of copper, which exhibit the unique ability to furnish chiral products arising from SN2′ mode of addition. The desired allenyl-containing products are generated in up to 95% yield, >98% SN2′ selectivity and 99:1 enantiomeric ratio (er). Site-selective NHC–Cu-catalyzed hydroboration of enantiomerically enriched allenes and conversion to the corresponding β-vinyl ketones demonstrates utility. PMID:22214185

  14. Metal-mediated controllable creation of secondary, tertiary, and quaternary carbon centers: a powerful strategy for the synthesis of iron, cobalt, and copper complexes with in situ generated substituted 1-pyridineimidazo[1,5-a]pyridine ligands.

    PubMed

    Chen, Yanmei; Li, Lei; Chen, Zhou; Liu, Yonglu; Hu, Hailiang; Chen, Wenqian; Liu, Wei; Li, Yahong; Lei, Tao; Cao, Yanyuan; Kang, Zhenghui; Lin, Miaoshui; Li, Wu

    2012-09-17

    An efficient strategy for the synthesis of a wide variety of coordination complexes has been developed. The synthetic protocol involves a solvothermal in situ metal-ligand reaction of picolinaldehyde, ammonium acetate, and transition-metal ions, leading to the generation of 12 coordination complexes supported by a novel class of substituted 1-pyridineimidazo[1,5-a]pyridine ligands (L1-L5). The ligands L1-L5 were afforded by metal-mediated controllable conversion of the aldehyde group of picolialdehyde into a ketone and secondary, tertiary, and quaternary carbon centers, respectively. Complexes of various nuclearities were obtained: from mono-, di-, and tetranuclear to 1D chain polymers. The structures of the in situ formed complexes could be controlled rationally via the choice of appropriate starting materials and tuning of the ratio of the starting materials. The plausible mechanisms for the formation of the ligands L1-L5 were proposed.

  15. Coupled Uranium-Series and (U-Th)/He Zircon Geochronology of the Emmons Lake Volcanic Center (ELVC): Dating the Record of Voluminous Tephra Production in Quaternary Eastern-Beringia.

    NASA Astrophysics Data System (ADS)

    Burgess, S. D.; Vazquez, J. A.; Grove, M. J.; Coble, M. A.; Hourigan, J. K.; Waythomas, C. F.; Coombs, M. L.; Wallace, K.

    2015-12-01

    Tephrochronology is an invaluable tool used to date, link, and reconstruct paleo-environments, climates, and landscapes. Single tephra layers represent isochronous markers across broad regions, thus accurate and precise temporal constraints on the timing of eruption are critical to their utility. If a U-bearing accessory phase such as zircon is present, U/Pb, U-series, and (U-Th)/He geochronometers may be selectively applied. Application of multiple geochronometers to the same sample corroborates accuracy, can potentially resolve mineral crystallization and volcano eruption dates, and can define an eruption age from inherited crystals, assuming complete thermal resetting of the (U-Th)/He system upon crystal incorporation into magma prior to eruption. The Emmons Lake Volcanic Center is one of the largest Quaternary volcanic systems in the Aleutian volcanic arc, and is characterized by at least two major caldera-forming eruptions. C1 has been dated by 40Ar/39Ar at ~238 ka, and was originally proposed as the source for the Old Crow tephra, the largest and most widespread Quaternary tephra in eastern Beringia, and a critical time horizon for reconstruction of Pleistocene paleo-environment and climate. C2 produced the widespread Dawson tephra, and has been dated indirectly by radiocarbon at ~27 ka. We present in-situ grain-surface ion microprobe (SHRIMP-RG) 238U-230Th and/or U/Pb data on a suite of autocrysitc zircon grains from a C1 sample, the Old Crow, and from the Dawson. On these same zircon crystals, we utilize a noble gas sector mass spectrometer to make sensitive, low blank, single crystal 4He measurements. With these datasets, we investigate the temporal and potential genetic relationship between C1 and Old Crow, and place absolute radiogenic time constraints on the C2 eruption. Coupled 238U-230Th and sector field (U-Th)/He application shows significant promise for generating accurate, precise dates for Quaternary tephra bearing a U-rich accessory mineral phase.

  16. Carbon nanotube network embroidered graphene films for monolithic all-carbon electronics.

    PubMed

    Shi, Enzheng; Li, Hongbian; Yang, Long; Hou, Junfeng; Li, Yuanchang; Li, Li; Cao, Anyuan; Fang, Ying

    2015-01-27

    A unique cage growth of graphene is developed by using carbon nanotube (CNT) spider webs as porous templates, resulting in CNT/graphene hybrids with high conductivity and mechanical flexibility. Furthermore, monolithic all-carbon transistors with graphene as active elements and CNT/graphene hybrids as contacts and interconnects are directly formed by chemical synthesis, and flexible all-carbon bioelectronics are subsequently demonstrated for in vivo mapping of cardiac signals. PMID:25607917

  17. Partitioning the Quaternary

    NASA Astrophysics Data System (ADS)

    Gibbard, Philip L.; Lewin, John

    2016-11-01

    We review the historical purposes and procedures for stratigraphical division and naming within the Quaternary, and summarize the current requirements for formal partitioning through the International Commission on Stratigraphy (ICS). A raft of new data and evidence has impacted traditional approaches: quasi-continuous records from ocean sediments and ice cores, new numerical dating techniques, and alternative macro-models, such as those provided through Sequence Stratigraphy and Earth-System Science. The practical usefulness of division remains, but there is now greater appreciation of complex Quaternary detail and the modelling of time continua, the latter also extending into the future. There are problems both of commission (what is done, but could be done better) and of omission (what gets left out) in partitioning the Quaternary. These include the challenge set by the use of unconformities as stage boundaries, how to deal with multiphase records in ocean and terrestrial sediments, what happened at the 'Early-Mid- (Middle) Pleistocene Transition', dealing with trends that cross phase boundaries, and the current controversial focus on how to subdivide the Holocene and formally define an 'Anthropocene'.

  18. Magnetism of quaternary sediments

    NASA Astrophysics Data System (ADS)

    Heller, Friedrich

    Magnetism of Quaternary sediments was the topic of a well-attended symposium held during the 13th INQUA (International Union of Quaternary Research) congress in Beijing, China, August 2-9. More than 40 papers were delivered by scientists from Belgium, England, France, Germany, Japan, New Zealand, Sweden, Switzerland, Taiwan, the United States, the Soviet Union, Yugoslavia, and other countries. The host country contributed to a productive session that was part of the first large scientific meeting to take place in Beijing after the June 4, 1989, upheaval.Nearly half of the studies focused on paleomagnetic and rock magnetic properties of loess in Alaska, Central Asia, China, and New Zealand. Magnetostratigraphic polarity dating was done at some sections in the western (Shaw et al.) and central Chinese loess plateau (Bai and Hus; Wang and Evans; Yue). The interpretation of the polarity pattern found in the western loess plateau still is not unambiguous. In the central part, certain polarity boundaries, such as the Brunhes/Matuyama (B/M) boundary, are found in slightly different stratigraphic positions (Hus et al.; Yue). In deep-sea sediments the lock-in depth of natural remanent magnetization (NRM) at the B/M boundary seems to be a linear function of sedimentation rate (de Menocal et al.). Although the magnetization process in the Chinese loess is not well understood, detailed records of polarity transitions have been reported for the B/M and the Jaramillo R→N transition (Ma et al.; Rolph).

  19. All Carbon-Based Photodetectors: An eminent integration of graphite quantum dots and two dimensional graphene

    PubMed Central

    Cheng, Shih-Hao; Weng, Tong-Min; Lu, Meng-Lin; Tan, Wei-Chun; Chen, Ju-Ying; Chen, Yang-Fang

    2013-01-01

    Photodetectors with ultrahigh sensitivity based on the composite made with all carbon-based materials consisting of graphite quantum dots (QDs), and two dimensional graphene crystal have been demonstrated. Under light illumination, remarkably, a photocurrent responsivity up to 4 × 107 AW−1 can be obtained. The underlying mechanism is attributed to the spatial separation of photogenerated electrons and holes due to the charge transfer caused by the appropriate band alignment across the interface between graphite QDs and graphene. Besides, the large absorptivity of graphite QDs and the excellent conductivity of the graphene sheet also play significant roles. Our result therefore demonstrates an outstanding illustration for the integration of the distinct properties of nanostructured carbon materials with different dimensionalities to achieve highly efficient devices. Together with the associated mechanism, it paves a valuable step for the further development of all carbon-based, cheap, and non-toxic optoelectronics devices with excellent performance. PMID:24045846

  20. Designing electronic anisotropy of three-dimensional carbon allotropes for the all-carbon device

    SciTech Connect

    Xu, Li-Chun Song, Xian-Jiang; Yang, Zhi; Li, Xiu-Yan; Wang, Ru-Zhi; Yan, Hui

    2015-07-13

    Extending two-dimensional (2D) graphene nanosheets to a three-dimensional (3D) network can enhance the design of all-carbon electronic devices. Based on the great diversity of carbon atomic bonding, we have constructed four superlattice-type carbon allotrope candidates, containing sp{sup 2}-bonding transport channels and sp{sup 3}-bonding insulating layers, using density functional theory. It was demonstrated through systematic simulations that the ultra-thin insulating layer with only three-atom thickness can switch off the tunneling transport and isolate the electronic connection between the adjacent graphene strips, and these alternating perpendicular strips also extend the electron road from 2D to 3D. Designing electronic anisotropy originates from the mutually perpendicular π bonds and the rare partial charge density of the corresponding carriers in insulating layers. Our results indicate the possibility of producing custom-designed 3D all-carbon devices with building blocks of graphene and diamond.

  1. High-performance all-carbon yarn micro-supercapacitor for an integrated energy system.

    PubMed

    Meng, Qinghai; Wu, Haiping; Meng, Yuena; Xie, Ke; Wei, Zhixiang; Guo, Zhengxiao

    2014-06-25

    Single-walled carbon nanotubes and chitosan composite yarn is prepared using a wet-spinning method. After thermal treatment, mesoporous all-carbon yarn is obtained. Based on this material, flexible all-solid-state yarn micro-supercapacitors are fabricated. Electrochemical results show high specific capacitance and energy density, good rate capability and stable cycling life. Results of this research offer prospect for application in portable and wearable electronics. PMID:24692229

  2. All carbon coaxial supercapacitors based on hollow carbon nanotube sleeve structure.

    PubMed

    Zang, Xiaobei; Xu, Ruiqiao; Zhang, Yangyang; Li, Xinming; Zhang, Li; Wei, Jinquan; Wang, Kunlin; Zhu, Hongwei

    2015-01-30

    All carbon coaxial supercapacitors based on hollow carbon nanotube (CNT) sleeve structure are assembled and tested. The key advantage of the structure is that the inner core electrode is variable from CNT sleeve sponges, to CNT fibers, reduced graphene oxide fibers, and graphene woven fabrics. By changing core electrodes from sleeve sponges to CNT fibers, the electrochemical performance has been significantly enhanced. The capacitance based on sleeve sponge + CNT fiber double the capacitances of double-sleeve sponge supercapacitors thanks to reduction of the series and internal resistances. Besides, the coaxial sleeve structure possesses many other features, including high rate capacitance, long cycle life, and good flexibility. PMID:25556604

  3. Two- and Three-Dimensional All-Carbon Nanomaterial Assemblies for Tissue Engineering and Regenerative Medicine.

    PubMed

    Lalwani, Gaurav; Patel, Sunny C; Sitharaman, Balaji

    2016-06-01

    Carbon nanomaterials such as carbon nanotubes and graphene have gained significant interest in the fields of materials science, electronics and biomedicine due to their interesting physiochemical properties. Typically these carbon nanomaterials have been dispersed in polymeric matrices at low concentrations to improve the functional properties of nanocomposites employed as two-dimensional (2D) substrates or three-dimensional (3D) porous scaffolds for tissue engineering applications. There has been a growing interest in the assembly of these nanomaterials into 2D and 3D architectures without the use of polymeric matrices, surfactants or binders. In this article, we review recent advances in the development of 2D or 3D all-carbon assemblies using carbon nanotubes or graphene as nanoscale building-block biomaterials for tissue engineering and regenerative medicine applications.

  4. All-carbon nanoswitch based on C70 molecule: A first principles study

    NASA Astrophysics Data System (ADS)

    OuYang, Fangping; Xu, Hui; Fan, Toujiao

    2007-09-01

    We have demonstrated the electron transport properties of an all-carbon molecular junction based on the C70 molecule connecting with two armchair single-wall carbon nanotubes using first principles transport calculations. It is shown that the Landauer conductance of this carbon hybrid system can be tuned within several orders of magnitude not only by changing the orientation of the C70 molecule but also by rotating one of the tubes around the symmetry axis of the system at fixed distances. This fact could make this pure-carbon molecular system a possible candidate for a nanoelectronic switching device. Moreover, we have also studied the nitrogen doping effect of such a molecular device. The results reveal that molecular configuration selection and nitrogen doping would play important roles in such switching devices.

  5. Fabrication and Characterization of Three-Dimensional Macroscopic All-Carbon Scaffolds

    PubMed Central

    Lalwani, Gaurav; Kwaczala, Andrea Trinward; Kanakia, Shruti; Patel, Sunny C.; Judex, Stefan; Sitharaman, Balaji

    2012-01-01

    We report a simple method to fabricate macroscopic, 3-D, free standing, all-carbon scaffolds (porous structures) using multiwalled carbon nanotubes (MWCNTs) as the starting materials. The scaffolds prepared by radical initiated thermal crosslinking, and annealing of MWCNTs possess macroscale interconnected pores, robust structural integrity, stability, and conductivity. The porosity of the three-dimensional structure can be controlled by varying the amount of radical initiator, thereby allowing the design of porous scaffolds tailored towards specific potential applications. This method also allows the fabrication of 3-D scaffolds using other carbon nanomaterials such as single-walled carbon nanotubes, fullerenes, and graphene indicating that it could be used as a versatile method for 3-D assembly of carbon nanostructures with pi bond networks. PMID:23436939

  6. Quaternary alkaloids of tinospora species.

    PubMed

    Bisset, N G; Nwaiwu, J

    1983-08-01

    The occurrence of quaternary alkaloids in TINOSPORA (and PARABAENA) species (Menispermaceae) has been studied. The main components were generally the protoberberine bases berberine and palmatine, with jatrorrhizine an occasional minor constituent, and the aporphine base magnoflorine. Choline was also often present. Only magnoflorine was detected in the PARABAENA material examined. PMID:17404996

  7. Eco-friendly all-carbon paper electronics fabricated by a solvent-free drawing method

    NASA Astrophysics Data System (ADS)

    Kanaparthi, Srinivasulu; Badhulika, Sushmee

    2016-03-01

    Here we report the fabrication of high-performance all-carbon temperature and infrared (IR) sensors with a solvent-free multiwalled carbon nanotube (MWCNT) trace as the sensing element and commercial graphite pencil trace as the electrical contact on recyclable and biodegradable cellulose filter paper without using any toxic materials or complex procedures. The temperature sensor shows a large negative temperature coefficient of resistance (TCR) in the range of -3100 ppm K-1 to -4900 ppm K-1, which is comparable to available commercial temperature sensors, and an activation energy of 34.85 meV. The IR sensor shows a high responsivity of 58.5 V W-1, which is greater than reported IR sensors with similar dimensions. A detailed study of the conduction mechanism in MWCNTs with temperature and the photo response with IR illumination was done and it was found that the conduction is due to thermally assisted hopping in band tails and the photo response is bolometric in nature. The successful fabrication of these sensors on cellulose filter paper with a comparable performance to existing components indicates that it is possible to fabricate high-performance electronics using low-cost, eco-friendly materials without the need for expensive clean-room processing techniques or harmful chemicals.

  8. Eco-friendly all-carbon paper electronics fabricated by a solvent-free drawing method.

    PubMed

    Kanaparthi, Srinivasulu; Badhulika, Sushmee

    2016-03-01

    Here we report the fabrication of high-performance all-carbon temperature and infrared (IR) sensors with a solvent-free multiwalled carbon nanotube (MWCNT) trace as the sensing element and commercial graphite pencil trace as the electrical contact on recyclable and biodegradable cellulose filter paper without using any toxic materials or complex procedures. The temperature sensor shows a large negative temperature coefficient of resistance (TCR) in the range of -3100 ppm K(-1) to -4900 ppm K(-1), which is comparable to available commercial temperature sensors, and an activation energy of 34.85 meV. The IR sensor shows a high responsivity of 58.5 V W(-1), which is greater than reported IR sensors with similar dimensions. A detailed study of the conduction mechanism in MWCNTs with temperature and the photo response with IR illumination was done and it was found that the conduction is due to thermally assisted hopping in band tails and the photo response is bolometric in nature. The successful fabrication of these sensors on cellulose filter paper with a comparable performance to existing components indicates that it is possible to fabricate high-performance electronics using low-cost, eco-friendly materials without the need for expensive clean-room processing techniques or harmful chemicals. PMID:26854529

  9. Andrei Sher and Quaternary science

    NASA Astrophysics Data System (ADS)

    Kuzmina, Svetlana; Lister, Adrian M.; Edwards, Mary E.

    2011-08-01

    Andrei Sher (1939-2008) was a key individual in Beringian studies who made substantial and original contributions, but also, importantly, built bridges between western and eastern Beringian scientists spanning some five decades of research. He is perhaps best known as a Quaternary palaeontologist, specializing in large mammals, and mammoths in particular, but his field of his scientific research was much broader, encompassing Quaternary geology, stratigraphy, geocryology, and paleoenvironmental reconstructions. He worked mainly in Siberia, in the Kolyma and Indigirka lowlands, and Chukotka, but also completed fieldwork in Alaska and Yukon through joint projects with American and Canadian scientists. Andrei was an active scientist until the last days of his life. He was involved in many different research projects ranging from mammoth evolution, fossil insects and environmental changes and ancient DNA. Without Andrei's connections between researchers, many unique discoveries would likely be unknown.

  10. Quaternary ecology: A paleoecological perspective

    SciTech Connect

    Delcourt, H.R.; Delcourt, P.A.

    1991-01-01

    This book considers issues and problems in ecology which may be illuminated, if not solved, by considering paleoecology. The five central chapters include a discussion of application of Quaternary ecology to future global climate change, including global warming. Other areas presented include: population dispersal, invasions, expansions, and migrations; plant successions; ecotones; factors in community structure; ecosystem patterns and processes. Published case studies are numerous. The role played by continuing climatic change in vegetation change is acknowledged but not stressed.

  11. 40 CFR 721.4095 - Quaternary ammonium alkyltherpropyl trialkylamine halides.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Quaternary ammonium alkyltherpropyl... Specific Chemical Substances § 721.4095 Quaternary ammonium alkyltherpropyl trialkylamine halides. (a... generically as quaternary ammonium alkyltherpropyl trialkylamine halides (PMNs...

  12. 40 CFR 721.4095 - Quaternary ammonium alkyltherpropyl trialkylamine halides.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Quaternary ammonium alkyltherpropyl... Specific Chemical Substances § 721.4095 Quaternary ammonium alkyltherpropyl trialkylamine halides. (a... generically as quaternary ammonium alkyltherpropyl trialkylamine halides (PMNs...

  13. Ancient biomolecules in Quaternary palaeoecology

    NASA Astrophysics Data System (ADS)

    Hofreiter, Michael; Collins, Matthew; Stewart, John R.

    2012-02-01

    The last few years have seen an enormous proliferation of ancient biomolecules research, especially in the field of ancient DNA. Ancient DNA studies have been transformed by the advent of next generation sequencing, with the first Pleistocene sample being analysed in 2005, and several complete and draft genomes that have been compiled from ancient DNA to date. At the same time, although less conspicuous, research on ancient proteins has also seen advances, with the time limit for research on ancient biomolecules now extending to over 1 million years. Here we review which effects these developments have on research in Quaternary science. We identify several lines of research that have the potential to profit substantially from these recent developments in ancient biomolecules research. First, the identification of taxa can be made using ancient biomolecules, and in the case of ancient DNA, specimens can even be assigned to specific populations within a species. Second, increasingly large DNA data sets from Pleistocene animals allow the elucidation of ever more precise pictures of the population dynamic processes whereby organisms respond to climate and environmental change. With the accompanying better understanding of process in the Quaternary, past ecologies can also more realistically be interpreted from proxy data sets. The dominant message from this research so far is that the Quaternary saw a great deal more dynamism in populations than had been forecast by conventional palaeoecology. This suggests that reconstructions of past environmental conditions need to be done with caution. Third, ancient DNA can also now be obtained directly from sediments to elucidate the presence of both plant and animal species in an area even in the absence of identifiable fossils, be it macro- or micro-fossils. Finally, the analysis of proteins enables the identification of bone remains to genus and sometimes species level far beyond the survival time of DNA, at least in temperate

  14. Stereoselective Synthesis of Quaternary Proline Analogues

    PubMed Central

    Calaza, M. Isabel

    2009-01-01

    This review describes available methods for the diastereoselective and asymmetric synthesis of quaternary prolines. The focus is on the preparation of α-functionalized prolines with the pyrrolidine moiety not embedded in a polycyclic frame. The diverse synthetic approaches are classified according to the bond which is formed to complete the quaternary skeleton. PMID:19655047

  15. Quaternary faults of west Texas

    SciTech Connect

    Collins, E.W.; Raney, J.A. . Bureau of Economic Geology)

    1993-04-01

    North- and northwest-striking intermontane basins and associated normal faults in West Texas and adjacent Chihuahua, Mexico, formed in response to Basin and Range tectonism that began about 24 Ma ago. Data on the precise ages of faulted and unfaulted Quaternary deposits are sparse. However, age estimates made on the basis of field stratigraphic relationships and the degree of calcic soil development have helped determine that many of the faults that bound the basin margins ruptured since the middle Pleistocene and that some faults probably ruptured during the Holocene. Average recurrence intervals between surface ruptures since the middle Pleistocene appear to be relatively long, about 10,000 to 100,000 yr. Maximum throw during single rupture events have been between 1 and 3 m. Historic seismicity in West Texas is low compared to seismicity in many parts of the Basin and Range province. The largest historic earthquake, the 1931 Valentine earthquake in Ryan Flat/Lobo Valley, had a magnitude of 6.4 and no reported surface rupture. The most active Quaternary faults occur within the 120-km-long Hueco Bolson, the 70-km-long Red Light Bolson, and the > 200-km-long Salt Basins/Wild Horse Flat/Lobo Valley/Ryan Flat.

  16. Intermolecular C-H Quaternary Alkylation of Aniline Derivatives Induced by Visible-Light Photoredox Catalysis.

    PubMed

    Cheng, Jie; Deng, Xia; Wang, Guoqiang; Li, Ying; Cheng, Xu; Li, Guigen

    2016-09-16

    The intermolecular direct C-H alkylation of aniline derivatives with α-bromo ketones to build a quaternary carbon center was reported with a visible-light catalysis procedure. The reaction covers a variety of functional groups with good to excellent yields. A regioselectivity favoring the ortho position for the amine group was observed and investigated with Fukui indices and spectral methods.

  17. All-carbon based graphene field effect transistor with graphitic electrodes fabricated by e-beam direct writing on PMMA.

    PubMed

    Chen, Wei; Yu, Yayun; Zheng, Xiaoming; Qin, Shiqiao; Wang, Fei; Fang, Jingyue; Wang, Guang; Wang, Chaocheng; Wang, Li; Peng, Gang; Zhang, Xue-Ao

    2015-07-21

    A so called all-carbon based graphene field effect transistor (GFET) in which the electrodes are composed of graphite-like nano-sheets instead of metals in the traditional devices is fabricated by one-step e-beam direct writing (EBDW). It is also found that the graphite-like nano-sheets in electrodes are perpendicular to the channel graphene, which is confirmed by the transmission electron microscopy (HRTEM). The one-step fabrication of the carbonaceous electrodes is more convenient and lower-cost comparing to the preparation of traditional metal electrodes and can be applied to many other nano-electronic devices.

  18. All-carbon based graphene field effect transistor with graphitic electrodes fabricated by e-beam direct writing on PMMA

    PubMed Central

    Chen, Wei; Yu, Yayun; Zheng, Xiaoming; Qin, Shiqiao; Wang, Fei; Fang, Jingyue; Wang, Guang; Wang, Chaocheng; Wang, Li; Peng, Gang; Zhang, Xue-Ao

    2015-01-01

    A so called all-carbon based graphene field effect transistor (GFET) in which the electrodes are composed of graphite-like nano-sheets instead of metals in the traditional devices is fabricated by one-step e-beam direct writing (EBDW). It is also found that the graphite-like nano-sheets in electrodes are perpendicular to the channel graphene, which is confirmed by the transmission electron microscopy (HRTEM). The one-step fabrication of the carbonaceous electrodes is more convenient and lower-cost comparing to the preparation of traditional metal electrodes and can be applied to many other nano-electronic devices. PMID:26195033

  19. Book Review: Reconstructing Quaternary Environments

    NASA Astrophysics Data System (ADS)

    Bridgland, David R.; Evans, David J. A.; Roberts, David H.

    2016-02-01

    A third edition of this, the foremost Quaternary textbook, is most welcome, coming seventeen years after the 1997 second edition (which was 13 years after the first). The general impression is one of advancement, not least because of the extensive updating of literature cited and examples used, with the status maintained of an impressive compendium of a specialism with a very wide subject base. Some changes are cosmetic, with chapter and section headers having a more modern style and a profusion of new colour photographs and diagrams. Some of the latter are redrawn from black and white figures in the previous edition, although not all have been improved, as some are smaller and have been simplified. For example, black and white Fig. 3.10 of the Second Edition compares very favourably with the much smaller colour 3.17 in this latest volume (erratic sources). On the plus side, the number change, for a figure that appears in the same place within the chapter, shows that the latest edition is considerably better illustrated than its predecessor, perhaps accounting for a significant proportion of the increased page total (up from 446 to 538).

  20. The Irish quaternary fauna project

    NASA Astrophysics Data System (ADS)

    Woodman, Peter; Mccarthy, Margaret; Monaghan, Nigel

    Much of Ireland's Pleistocene and Early Holocene mammalian faunas are derived from a series of late 19th/early 20th century cave excavations. In many instances it would appear that the deposits containing these faunal remains were disturbed. This project assessed the chronological range of the mammalian species present in the caves using 14C dating, in particular accelerator mass spectrometry (AMS). The research has shown that (1) a wide range of mammals colonised Ireland in the period between at least 45 ka and 20 ka, with some elements surviving until close to the Last Glacial Maximum; (2) a more restricted range of species re-colonised Ireland during the Lateglacial period, with evidence for a slightly more temperature fauna being replaced by an Arctic fauna at about 11 ka; (3) certain elements of Ireland's Holocene fauna may have survived through from the Lateglacial into the Holocene; (4) there is a lack of evidence for red deer, Cervus elaphus, being present in the Early Holocene in Ireland; and (5) horse is only documented in the Irish Holocene from 4 ka. The paper also discusses the implications of the Quaternary Fauna Project for the Late Pleistocene of Ireland, the mechanism and period of colonisation of Ireland as well as the introduction of domesticates in the Mid Holocene.

  1. Ice Age refugia and Quaternary extinctions: An issue of Quaternary evolutionary palaeoecology

    NASA Astrophysics Data System (ADS)

    Stewart, John R.; Cooper, Alan

    2008-12-01

    Quaternary palaeoecology, as a discipline, involves the analysis of a large range of fossil organisms from the last ca. 2 million years. This paper considers the role that these Quaternary records can take in better understanding the evolution of those organisms. We also discuss the surprisingly low uptake of evolutionary biology in Quaternary palaeoecological studies. This leads us to encourage an advance on both these fronts with a greater degree of collaboration with phylogeographic and ancient DNA researchers. These discussions accompany a summary of a special issue of Quaternary Science Reviews representing the proceedings of the XVII INQUA held in Cairns Australia in 2007. This special issue includes papers on a wide variety of Quaternary evolutionary palaeoecological and population dynamic subjects including extinct Pacific Island palm trees, Beringian beetles, Scandinavian trees, and the effects on human and animal populations of an extraterrestrial impact event in the Late Glacial of North America.

  2. Quaternary Magmatism in the Cascades - Geologic Perspectives

    USGS Publications Warehouse

    Hildreth, Wes

    2007-01-01

    Foreward The Cascade magmatic arc is a belt of Quaternary volcanoes that extends 1,250 km from Lassen Peak in northern California to Meager Mountain in Canada, above the subduction zone where the Juan de Fuca Plate plunges beneath the North American Plate. This Professional Paper presents a synthesis of the entire volcanic arc, addressing all 2,300 known Quaternary volcanoes, not just the 30 or so visually prominent peaks that comprise the volcanic skyline. Study of Cascade volcanoes goes back to the geological explorers of the late 19th century and the seminal investigations of Howel Williams in the 1920s and 1930s. However, major progress and application of modern scientific methods and instrumentation began only in the 1970s with the advent of systematic geological, geophysical, and geochemical studies of the entire arc. Initial stimulus from the USGS Geothermal Research Program was enhanced by the USGS Volcano Hazards Program following the 1980 eruption of Mount St. Helens. Together, these two USGS Programs have provided more than three decades of stable funding, staffing, and analytical support. This Professional Paper summarizes the resultant USGS data sets and integrates them with the parallel contributions of other investigators. The product is based upon an all-encompassing and definitive geological database, including chemical and isotopic analyses to characterize the rocks and geochronology to provide the critical time constraints. Until now, this massive amount of data has not been summarized, and a systematic and uniform interpretation firmly grounded in geological fact has been lacking. Herein lies the primary utility of this Cascade volume. It not only will be the mandatory starting point for new workers, but also will provide essential geological context to broaden the perspectives of current investigators of specific Cascade volcanoes. Wes Hildreth's insightful understanding of volcanic processes and his uncompromising scientific integrity make him

  3. All-carbon multi-electrode array for real-time in vitro measurements of oxidizable neurotransmitters.

    PubMed

    Picollo, Federico; Battiato, Alfio; Bernardi, Ettore; Plaitano, Marilena; Franchino, Claudio; Gosso, Sara; Pasquarelli, Alberto; Carbone, Emilio; Olivero, Paolo; Carabelli, Valentina

    2016-01-01

    We report on the ion beam fabrication of all-carbon multi electrode arrays (MEAs) based on 16 graphitic micro-channels embedded in single-crystal diamond (SCD) substrates. The fabricated SCD-MEAs are systematically employed for the in vitro simultaneous amperometric detection of the secretory activity from populations of chromaffin cells, demonstrating a new sensing approach with respect to standard techniques. The biochemical stability and biocompatibility of the SCD-based device combined with the parallel recording of multi-electrodes array allow: i) a significant time saving in data collection during drug screening and/or pharmacological tests over a large number of cells, ii) the possibility of comparing altered cell functionality among cell populations, and iii) the repeatition of acquisition runs over many cycles with a fully non-toxic and chemically robust bio-sensitive substrate. PMID:26857940

  4. All-carbon multi-electrode array for real-time in vitro measurements of oxidizable neurotransmitters

    NASA Astrophysics Data System (ADS)

    Picollo, Federico; Battiato, Alfio; Bernardi, Ettore; Plaitano, Marilena; Franchino, Claudio; Gosso, Sara; Pasquarelli, Alberto; Carbone, Emilio; Olivero, Paolo; Carabelli, Valentina

    2016-02-01

    We report on the ion beam fabrication of all-carbon multi electrode arrays (MEAs) based on 16 graphitic micro-channels embedded in single-crystal diamond (SCD) substrates. The fabricated SCD-MEAs are systematically employed for the in vitro simultaneous amperometric detection of the secretory activity from populations of chromaffin cells, demonstrating a new sensing approach with respect to standard techniques. The biochemical stability and biocompatibility of the SCD-based device combined with the parallel recording of multi-electrodes array allow: i) a significant time saving in data collection during drug screening and/or pharmacological tests over a large number of cells, ii) the possibility of comparing altered cell functionality among cell populations, and iii) the repeatition of acquisition runs over many cycles with a fully non-toxic and chemically robust bio-sensitive substrate.

  5. Three-dimensional bicomponent supramolecular nanoporous self-assembly on a hybrid all-carbon atomically flat and transparent platform.

    PubMed

    Li, Juan; Wieghold, Sarah; Öner, Murat Anil; Simon, Patrick; Hauf, Moritz V; Margapoti, Emanuela; Garrido, Jose A; Esch, Friedrich; Palma, Carlos-Andres; Barth, Johannes V

    2014-08-13

    Molecular self-assembly is a versatile nanofabrication technique with atomic precision en route to molecule-based electronic components and devices. Here, we demonstrate a three-dimensional, bicomponent supramolecular network architecture on an all-carbon sp(2)-sp(3) transparent platform. The substrate consists of hydrogenated diamond decorated with a monolayer graphene sheet. The pertaining bilayer assembly of a melamine-naphthalenetetracarboxylic diimide supramolecular network exhibiting a nanoporous honeycomb structure is explored via scanning tunneling microscopy initially at the solution-highly oriented pyrolytic graphite interface. On both graphene-terminated copper and an atomically flat graphene/diamond hybrid substrate, an assembly protocol is demonstrated yielding similar supramolecular networks with long-range order. Our results suggest that hybrid platforms, (supramolecular) chemistry and thermodynamic growth protocols can be merged for in situ molecular device fabrication. PMID:25115337

  6. All-carbon multi-electrode array for real-time in vitro measurements of oxidizable neurotransmitters

    PubMed Central

    Picollo, Federico; Battiato, Alfio; Bernardi, Ettore; Plaitano, Marilena; Franchino, Claudio; Gosso, Sara; Pasquarelli, Alberto; Carbone, Emilio; Olivero, Paolo; Carabelli, Valentina

    2016-01-01

    We report on the ion beam fabrication of all-carbon multi electrode arrays (MEAs) based on 16 graphitic micro-channels embedded in single-crystal diamond (SCD) substrates. The fabricated SCD-MEAs are systematically employed for the in vitro simultaneous amperometric detection of the secretory activity from populations of chromaffin cells, demonstrating a new sensing approach with respect to standard techniques. The biochemical stability and biocompatibility of the SCD-based device combined with the parallel recording of multi-electrodes array allow: i) a significant time saving in data collection during drug screening and/or pharmacological tests over a large number of cells, ii) the possibility of comparing altered cell functionality among cell populations, and iii) the repeatition of acquisition runs over many cycles with a fully non-toxic and chemically robust bio-sensitive substrate. PMID:26857940

  7. Catalytic Enantioselective Synthesis of Quaternary Carbon Stereocenters

    PubMed Central

    Quasdorf, Kyle W.; Overman, Larry E.

    2015-01-01

    Preface Quaternary carbon stereocenters–carbon atoms to which four distinct carbon substituents are attached–are common features of molecules found in nature. However, prior to recent advances in chemical catalysis, there were few methods available for constructing single stereoisomers of this important structural motif. Here we discuss the many catalytic enantioselective reactions developed during the past decade for synthesizing organic molecules containing such carbon atoms. This progress now makes it possible to selectively incorporate quaternary stereocenters in many high-value organic molecules for use in medicine, agriculture, and other areas. PMID:25503231

  8. Gravity anomalies, Quaternary vents, and Quaternary faults in the southern Cascade Range, Oregon and California: Implications for arc and backarc evolution

    USGS Publications Warehouse

    Blakely, R.J.; Christiansen, R.L.; Guffanti, M.; Wells, R.E.; Donnelly-Nolan, J. M.; Muffler, L.J. Patrick; Clynne, M.A.; Smith, James G.

    1997-01-01

    Isostatic residual gravity anomalies in the southern Cascade Range of northern California and southern Oregon are spatially correlated with broad zones of Quaternary magmatism as reflected by the total volume of Quaternary volcanic products, the distribution of Quaternary vents, and the anomalously low teleseismic P wave velocities in the upper 30 km of crust. The orientation of Quaternary faults also appears to be related to gravity anomalies and volcanism in this area, trending generally north-south within the magmatic regions and northwest-southeast as they enter the neighboring amagmatic zones to the north and south. The relationship between gravity anomalies, vent density, and fault orientations may indicate in a broad sense the strength of the middle and upper crust. The southern Cascade Range occupies a transition zone where horizontal stress is transferred from the northwest-southeast dextral shear of the Walker Lane belt to the east-west extension characteristic of the Cascade arc in central Oregon. Faulting along north-south strikes in the volcanically active areas indicates the east-west extensional stresses in thermally weakened crust, whereas northwest faulting between the volcanically active areas reflects the northwest trending, right lateral shear strain of the Walker Lane belt. The segmentation of the arc reflected in Quaternary magmatism may be caused by differential extension behind crustal blocks of the forearc rotating clockwise with respect to North America. In this view the volcanic centers at Mount Shasta, Medicine Lake volcano, and Lassen Peak in northern California are situated along the southern parts of the trailing edges of two distinct segments of the forearc where additional extension is implied by their differential clockwise rotation. U.S. copyright. Published in 1997 by the American Geophysical Union.

  9. Gravity anomalies, Quaternary vents, and Quaternary faults in the southern Cascade Range, Oregon and California: Implications for arc and backarc evolution

    NASA Astrophysics Data System (ADS)

    Blakely, Richard J.; Christiansen, Robert L.; Guffanti, Marianne; Wells, Ray E.; Donnelly-Nolan, Julie M.; Muffler, L. J. Patrick; Clynne, Michael A.; Smith, James G.

    1997-10-01

    Isostatic residual gravity anomalies in the southern Cascade Range of northern California and southern Oregon are spatially correlated with broad zones of Quaternary magmatism as reflected by the total volume of Quaternary volcanic products, the distribution of Quaternary vents, and the anomalously low teleseismic P wave velocities in the upper 30 km of crust. The orientation of Quaternary faults also appears to be related to gravity anomalies and volcanism in this area, trending generally north-south within the magmatic regions and northwest-southeast as they enter the neighboring amagmatic zones to the north and south. The relationship between gravity anomalies, vent density, and fault orientations may indicate in a broad sense the strength of the middle and upper crust. The southern Cascade Range occupies a transition zone where horizontal stress is transferred from the northwest-southeast dextral shear of the Walker Lane belt to the east-west extension characteristic of the Cascade arc in central Oregon. Faulting along north-south strikes in the volcanically active areas indicates the east-west extensional stresses in thermally weakened crust, whereas northwest faulting between the volcanically active areas reflects the northwest trending, right lateral shear strain of the Walker Lane belt. The segmentation of the arc reflected in Quaternary magmatism may be caused by differential extension behind crustal blocks of the forearc rotating clockwise with respect to North America. In this view the volcanic centers at Mount Shasta, Medicine Lake volcano, and Lassen Peak in northern California are situated along the southern parts of the trailing edges of two distinct segments of the forearc where additional extension is implied by their differential clockwise rotation.

  10. 40 CFR 721.655 - Ethoxylated alkyl quaternary ammonium compound.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Ethoxylated alkyl quaternary ammonium... Specific Chemical Substances § 721.655 Ethoxylated alkyl quaternary ammonium compound. (a) Chemical... as an ethoxylated alkyl quaternary ammonium compound (PMN P-96-573) is subject to reporting...

  11. 40 CFR 721.655 - Ethoxylated alkyl quaternary ammonium compound.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Ethoxylated alkyl quaternary ammonium... Specific Chemical Substances § 721.655 Ethoxylated alkyl quaternary ammonium compound. (a) Chemical... as an ethoxylated alkyl quaternary ammonium compound (PMN P-96-573) is subject to reporting...

  12. 40 CFR 721.655 - Ethoxylated alkyl quaternary ammonium compound.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Ethoxylated alkyl quaternary ammonium... Specific Chemical Substances § 721.655 Ethoxylated alkyl quaternary ammonium compound. (a) Chemical... as an ethoxylated alkyl quaternary ammonium compound (PMN P-96-573) is subject to reporting...

  13. 40 CFR 721.655 - Ethoxylated alkyl quaternary ammonium compound.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Ethoxylated alkyl quaternary ammonium... Specific Chemical Substances § 721.655 Ethoxylated alkyl quaternary ammonium compound. (a) Chemical... as an ethoxylated alkyl quaternary ammonium compound (PMN P-96-573) is subject to reporting...

  14. 40 CFR 721.655 - Ethoxylated alkyl quaternary ammonium compound.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Ethoxylated alkyl quaternary ammonium... Specific Chemical Substances § 721.655 Ethoxylated alkyl quaternary ammonium compound. (a) Chemical... as an ethoxylated alkyl quaternary ammonium compound (PMN P-96-573) is subject to reporting...

  15. 40 CFR 721.10569 - Tricyclic quaternary amine salt (generic).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Tricyclic quaternary amine salt... Specific Chemical Substances § 721.10569 Tricyclic quaternary amine salt (generic). (a) Chemical substance... tricyclic quaternary amine salt (PMN P-08-471) is subject to reporting under this section for...

  16. 40 CFR 721.10569 - Tricyclic quaternary amine salt (generic).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Tricyclic quaternary amine salt... Specific Chemical Substances § 721.10569 Tricyclic quaternary amine salt (generic). (a) Chemical substance... tricyclic quaternary amine salt (PMN P-08-471) is subject to reporting under this section for...

  17. 40 CFR 721.4467 - Quaternary ammonium hydroxide.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Quaternary ammonium hydroxide. 721... Substances § 721.4467 Quaternary ammonium hydroxide. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified generically as a quaternary ammonium...

  18. 40 CFR 721.4467 - Quaternary ammonium hydroxide.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Quaternary ammonium hydroxide. 721... Substances § 721.4467 Quaternary ammonium hydroxide. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified generically as a quaternary ammonium...

  19. Extensive Quaternary glaciations in eastern Turkey

    NASA Astrophysics Data System (ADS)

    Yeşilyurt, Serdar; Akçar, Naki; Doǧan, Uǧur; Yavuz, Vural; Ivy-Ochs, Susan; Vockenhuber, Christof; Schlunegger, Fritz; Schlüchter, Christian

    2016-04-01

    During cold periods in the Quaternary, global ice volume increased and as a result valley glaciers advanced and the vice versa occurred during the warm periods. Quaternary glacier fluctuations had been also recorded in the Turkish mountains. Recently, the chronology of Late Quaternary advances in the northern and western Turkish mountains was reconstructed by surface exposure dating. However, these advances in the eastern Turkey are not dated yet. In this study, we investigated paleoglaciations in Kavuşşahap Mountains, which is located to the south of Lake Van in eastern Turkey. These mountains are one of the extensively glaciated areas in Turkey. Glacial activity is evidenced by more than 20 U-shaped valleys. For instance, one of the prominent and well-preserved glacial landscapes of Turkey is situated in the Narlıca valley system. Lateral and terminal moraines in the valley system indicate more than 10 glacial advances. To build their chronology, 39 erratic carbonaceous boulders were sampled for surface exposure dating with cosmogenic 36Cl. We also reconstructed the ice margin reconstruction of the Narlıca paleoglacier using the accumulation area ratio and area-altitude balance ratio approaches. We estimated an equilibrium line altitude (ELA) of ca. 2900 m above sea level based on the maximum ice extend, which implied ca. 800 m decrease in the ELA during the Late Quaternary in comparison to the lower bound of the modern ELA estimate. The first results of the surface exposure dating will be presented.

  20. Intermolecular C-H Quaternary Alkylation of Aniline Derivatives Induced by Visible-Light Photoredox Catalysis.

    PubMed

    Cheng, Jie; Deng, Xia; Wang, Guoqiang; Li, Ying; Cheng, Xu; Li, Guigen

    2016-09-16

    The intermolecular direct C-H alkylation of aniline derivatives with α-bromo ketones to build a quaternary carbon center was reported with a visible-light catalysis procedure. The reaction covers a variety of functional groups with good to excellent yields. A regioselectivity favoring the ortho position for the amine group was observed and investigated with Fukui indices and spectral methods. PMID:27571116

  1. Crystal structures and optical properties of new quaternary strontium europium aluminate luminescent nanoribbons

    DOE PAGES

    Li, Xufan; Budai, John D.; Liu, Feng; Chen, Yu-Sheng; Howe, Jane Y.; Sun, Chengjun; Tischler, Jonathan Zachary; Meltzer, Richard; Pan, Zhengwei

    2014-11-12

    We report the synthesis and characterizations of three series of quaternary strontium europium aluminate (Sr-Eu-Al-O; SEAO) luminescent nanoribbons that show blue, green, and yellow luminescence from localized Eu2+ luminescent centers. These three series of SEAO nanoribbons are: blue luminescent, tetragonal Sr1-xEuxAl6O10 (01-xEuxAl2O4 (01-xEuxAl2O4 (0

  2. Highly Flexible Freestanding Porous Carbon Nanofibers for Electrodes Materials of High-Performance All-Carbon Supercapacitors.

    PubMed

    Liu, Ying; Zhou, Jinyuan; Chen, Lulu; Zhang, Peng; Fu, Wenbin; Zhao, Hao; Ma, Yufang; Pan, Xiaojun; Zhang, Zhenxing; Han, Weihua; Xie, Erqing

    2015-10-28

    Highly flexible porous carbon nanofibers (P-CNFs) were fabricated by electrospining technique combining with metal ion-assistant acid corrosion process. The resultant fibers display high conductivity and outstanding mechanical flexibility, whereas little change in their resistance can be observed under repeatedly bending, even to 180°. Further results indicate that the improved flexibility of P-CNFs can be due to the high graphitization degree caused by Co ions. In view of electrode materials for high-performance supercapacitors, this type of porous nanostructure and high graphitization degree could synergistically facilitate the electrolyte ion diffusion and electron transportation. In the three electrodes testing system, the resultant P-CNFs electrodes can exhibit a specific capacitance of 104.5 F g(-1) (0.2 A g(-1)), high rate capability (remain 56.5% at 10 A g(-1)), and capacitance retention of ∼94% after 2000 cycles. Furthermore, the assembled symmetric supercapacitors showed a high flexibility and can deliver an energy density of 3.22 Wh kg(-1) at power density of 600 W kg(-1). This work might open a way to improve the mechanical properties of carbon fibers and suggests that this type of freestanding P-CNFs be used as effective electrode materials for flexible all-carbon supercapacitors.

  3. Voltage-Gated Transport of Nanoparticles across Free-Standing All-Carbon-Nanotube-Based Hollow-Fiber Membranes.

    PubMed

    Wei, Gaoliang; Quan, Xie; Chen, Shuo; Fan, Xinfei; Yu, Hongtao; Zhao, Huimin

    2015-07-15

    Understanding the mechanism underlying controllable transmembrane transport observed in biological membranes benefits the development of next-generation separation membranes for a variety of important applications. In this work, on the basis of common structural features of cell membranes, a very simple biomimetic membrane system exhibiting gated transmembrane performance has been constructed using all-carbon-nanotube (CNT)-based hollow-fiber membranes. The conductive CNT membranes with hydrophobic pore channels can be positively or negatively charged and are consequently capable of regulating the transport of nanoparticles across their pore channels by their "opening" or "closing". The switch between penetration and rejection of nanoparticles through/by CNT membranes is of high efficiency and especially allows dynamic control. The underlying mechanism is that CNT pore channels with different polarities can prompt or prevent the formation of their noncovalent interactions with charged nanoparticles, resulting in their rejection or penetration by/through the CNT membranes. The theory about noncovalent interactions and charged pore channels may provide new insight into understanding the complicated ionically and bimolecularly gated transport across cell membranes and can contribute to many other important applications beyond the water purification and resource recovery demonstrated in this study. PMID:26103999

  4. Voltage-Gated Transport of Nanoparticles across Free-Standing All-Carbon-Nanotube-Based Hollow-Fiber Membranes.

    PubMed

    Wei, Gaoliang; Quan, Xie; Chen, Shuo; Fan, Xinfei; Yu, Hongtao; Zhao, Huimin

    2015-07-15

    Understanding the mechanism underlying controllable transmembrane transport observed in biological membranes benefits the development of next-generation separation membranes for a variety of important applications. In this work, on the basis of common structural features of cell membranes, a very simple biomimetic membrane system exhibiting gated transmembrane performance has been constructed using all-carbon-nanotube (CNT)-based hollow-fiber membranes. The conductive CNT membranes with hydrophobic pore channels can be positively or negatively charged and are consequently capable of regulating the transport of nanoparticles across their pore channels by their "opening" or "closing". The switch between penetration and rejection of nanoparticles through/by CNT membranes is of high efficiency and especially allows dynamic control. The underlying mechanism is that CNT pore channels with different polarities can prompt or prevent the formation of their noncovalent interactions with charged nanoparticles, resulting in their rejection or penetration by/through the CNT membranes. The theory about noncovalent interactions and charged pore channels may provide new insight into understanding the complicated ionically and bimolecularly gated transport across cell membranes and can contribute to many other important applications beyond the water purification and resource recovery demonstrated in this study.

  5. Toward all-carbon electronics: fabrication of graphene-based flexible electronic circuits and memory cards using maskless laser direct writing.

    PubMed

    Liang, Jiajie; Chen, Yongsheng; Xu, Yanfei; Liu, Zhibo; Zhang, Long; Zhao, Xin; Zhang, Xiaoliang; Tian, Jianguo; Huang, Yi; Ma, Yanfeng; Li, Feifei

    2010-11-01

    Owing to its extraordinary electronic property, chemical stability, and unique two-dimensional nanostructure, graphene is being considered as an ideal material for the highly expected all-carbon-based micro/nanoscale electronics. Herein, we present a simple yet versatile approach to constructing all-carbon micro/nanoelectronics using solution-processing graphene films directly. From these graphene films, various graphene-based microcosmic patterns and structures have been fabricated using maskless computer-controlled laser cutting. Furthermore, a complete system involving a prototype of a flexible write-once-read-many-times memory card and a fast data-reading system has been demonstrated, with infinite data retention time and high reliability. These results indicate that graphene could be the ideal material for fabricating the highly demanded all-carbon and flexible devices and electronics using the simple and efficient roll-to-roll printing process when combined with maskless direct data writing.

  6. Quaternary Tipping Points in Tropical Northern Australia

    NASA Astrophysics Data System (ADS)

    Moss, Patrick; Dunbar, Gavin; Croke, Jacky; Katunar, Rosie

    2016-04-01

    Tropical northern Queensland, particularly the volcanic Atherton Tableland, contains some of the most detailed and longest terrestrial palaeoenvironmental archives in Australia and when combined with adjacent marine sediment records provides key insight into potential environmental 'tipping points' for the entire Quaternary period and beyond. This presentation will provide an overview of some of the key tipping points (i.e. significant landscape transformation) that have occurred within the tropical northern Australian region over the Quaternary, as well as discussing potential causes and subsequent impacts of these transformation episodes. These events include the development of the Great Barrier Reef, transition from obliquity to eccentricity dominated glacial-interglacial cycles, the Mid-Brunhes event, the Oxygen Isotope Stage 6 episode, the arrival of people into the region, Last Glacial-Interglacial Transition and European settlement.

  7. [Quaternary prevention: containment as an ethical necessity].

    PubMed

    Martínez González, C; Riaño Galán, I; Sánchez Jacob, M; González de Dios, J

    2014-12-01

    The growing capacity of medicine to generate more iatrogenic events than ever, and the risk of unsustainability of health systems have led to new prevention concept: quaternary prevention aimed at restraining medicalization. Quaternary prevention is essential in the phenomenon called disease mongering, which could be translated as commercialization of disease. Encouraging this sort of prevention and halting the consequences of disease mongering requires the development of all the institutional potential for prevention, as well as all the personal willingness for restraint; it involves separating us from the unnecessary auspices of industry, being critical of our work, not being maleficent, respecting the principle of justice as managers of the limited public resources and making ourselves feel responsible for the social cost resulting from medical decisions. From this point of view, this work analyses neonatal screening, developments in the area of neonatology and primary health care.

  8. [Quaternary prevention: containment as an ethical necessity].

    PubMed

    Martínez González, C; Riaño Galán, I; Sánchez Jacob, M; González de Dios, J

    2014-12-01

    The growing capacity of medicine to generate more iatrogenic events than ever, and the risk of unsustainability of health systems have led to new prevention concept: quaternary prevention aimed at restraining medicalization. Quaternary prevention is essential in the phenomenon called disease mongering, which could be translated as commercialization of disease. Encouraging this sort of prevention and halting the consequences of disease mongering requires the development of all the institutional potential for prevention, as well as all the personal willingness for restraint; it involves separating us from the unnecessary auspices of industry, being critical of our work, not being maleficent, respecting the principle of justice as managers of the limited public resources and making ourselves feel responsible for the social cost resulting from medical decisions. From this point of view, this work analyses neonatal screening, developments in the area of neonatology and primary health care. PMID:24907862

  9. Quaternary geology of the Amazonian Lowland

    NASA Astrophysics Data System (ADS)

    Irion, Georg; Müller, Jens; Nunes de Mello, Jose; Junk, Wolfgang J.

    1995-09-01

    The Quaternary history of the Amazon lowlands is characterized by deposition of sediments of Andean provenance and by the influences of changing sea levels. Areas well above the present water tables were not reached by Pleistocene high-water stages. These areas have been intensively weathered since the Tertiary, forming hard lateritic weathering horizons. These weathering horizons are best explained by the relatively constant, humid tropical climate throughout the Quaternary. In the western Amazonian Lowland, flood plains corresponding to the different Pleistocene sea-level heights were formed. During low sea level, erosion in the drainage areas increased and the water levels of the central Amazon River system were lowered. Valleys drowned and lakes formed in the lower reaches of rivers and creeks during high sea-level stages. These lakes (ria lakes) remained in the valleys with rivers having a low sediment load. Seismic profiling (3.5 kHz) in some of these lakes clearly showed deposits of the three last periods of Quaternary high sea-level stages.

  10. 3-Quaternary ammonium 1-carba-1-dethiacephems.

    PubMed

    Cook, G K; McDonald, J H; Alborn, W; Boyd, D B; Eudaly, J A; Indelicato, J M; Johnson, R; Kasher, J S; Pasini, C E; Preston, D A

    1989-11-01

    A series of structurally unique 1-carba-1-dethiacephems is described. The structural stability of the 1-carba-1-dethiacephem nucleus was essential for the preparation of this series of 3-quaternary ammonium carbacephems. The known p-nitrobenzyl 7 beta-(phenoxyacetamido)- 3-[(trifluoromethyl)sulfonyl]oxy]-1-carba-1-dethia-3-cephem- 4-carboxylate served as both a quaternization substrate as well as a precursor to derivatives such as allyl 7 beta-[[2-[allyloxy)carbonyl]amino-4- thiazoly] (methoxyimino)acetyl]amino]-3-[(trifluoromethyl) sulfonyl] oxy]-1-carba-1-dethia-3-cephem-4-carboxylate. Quaternization of these enol triflates was accomplished either by dissolution in acetonitrile containing the base or by dissolution in the base, with or without warning to 50 degrees C. Bases nucleophilic enough to displace the triflate include a variety of substituted pyridines and N-methylimidazole. Deprotection then produced a very active series of 1-[7 beta-[(2-amino- 4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo- 1-azabicyclo[4.2.0]oct-2-en-3-yl] quaternary ammonium hydroxide inner salts. These compounds were extremely potent antibacterials against a broad range of Gram-positive and -negative bacteria including constitutive cephalosporinase producers, such as Enterobacter cloacae. The compounds exhibit similar hydrolysis kinetics and pharmacokinetics to the analogous cephalosporin-3'-quaternary ammonium salts.

  11. Aleksis Dreimanis: a legacy in Quaternary science

    NASA Astrophysics Data System (ADS)

    Hicock, Stephen R.; Menzies, John

    2000-12-01

    Aleksis Dreimanis was born and raised in Latvia. His interest in Quaternary and glacial geology began early and developed into a career that has spanned 7 decades. At age 20 he published his first paper in glacial geology and soon after began teaching at the University of Latvia. Teaching and research were interrupted by World War II but resumed at the Baltic University (Pinneberg, Germany), then at the University of Western Ontario where he has been ever since. Throughout his career, Dreimanis has successfully balanced the twin disciplines of Quaternary history and glacial geology. He was among the first to study quantitatively the relationship between till lithology and till formation and to study how glacial transport and dynamics affect till texture and deformation. With co-workers he developed the well-known stratigraphic scheme of the last glaciation in the Great Lakes region of North America. Aleksis became world-renowned through his committee work, especially as President of the INQUA Commission on Genesis and Lithology of Glacial Quaternary Deposits. His diplomacy, enthusiasm, and passion for his subject have inspired students and colleagues around the globe and resulted in remarkable international dialogue, cooperation, and consensus. Professor Aleksis Dreimanis is an honest scientist, a gentleman, and a true scholar who has left a rich legacy for future Quaternarists.

  12. Sex allocation and functional bias of quaternary and quinary flowers on same inflorescence in the hermaphrodite Ruta graveolens

    NASA Astrophysics Data System (ADS)

    Tang, Jing-Yu; Ren, Ming-Xun

    2011-09-01

    Intra-inflorescence variation in floral traits is important to understand the pollination function of an inflorescence and the real reproductive outputs of a plant. Ruta graveolens (Rutaceae) produce both quaternary (four petals and eight stamens) and quinary (five petals and ten stamens) flowers on the same cymes, while their pollination roles and the effects on the reproductive success remained unexplored. We experimentally examined the biomass of female versus male organs and pollen viability and stigma receptivity to explore the sex allocation patterns between the flowers. The breeding systems and reproductive outputs through either female function (seed set) or male function (pollen dispersal) were also studied for quinary and quaternary flowers to determine whether there was functional bias. The results showed that R. graveolens was protandrous, with a mixed mating system. Its stamens could slowly move one by one and only dehisce when positioning at the flower center, which could greatly enhance pollen dispersal. The first-opened quinary flower allocated significantly higher resources (dry biomass) in female organs while quaternary flowers allocated more resource in male organs. The quaternary flowers experienced higher pollen limitation in seed production but were more successful in pollen dispersal and the quinary flowers reproduced both through female and male functions. Our data suggested that quinary and quaternary flower on same inflorescence in R. graveolens functioned mainly as the sex role that most resources were allocated, which probably reflect an adaptation for floral phenology and pollination process in this plant.

  13. Synergistically enhanced activity of graphene quantum dots/graphene hydrogel composites: a novel all-carbon hybrid electrocatalyst for metal/air batteries.

    PubMed

    Wang, Mengran; Fang, Zhao; Zhang, Kai; Fang, Jing; Qin, Furong; Zhang, Zhian; Li, Jie; Liu, Yexiang; Lai, Yanqing

    2016-06-01

    Primary zinc/air batteries could be the next generation of energy storage devices because of their high power density and high safety. Graphene quantum dots nested in the graphene hydrogel have been proposed as excellent all-carbon hybrid oxygen reduction reaction (ORR) catalysts, indicative of their great potential in primary zinc/air batteries. PMID:27217121

  14. Quaternary amines as nitrosamine precursors: a role for consumer products?

    PubMed

    Kemper, Jerome M; Walse, Spencer S; Mitch, William A

    2010-02-15

    Nitrosamine formation has been associated with wastewater-impacted waters, but specific precursors within wastewater effluents have not been identified. Experiments indicated that nitrosamines form in low yields from quaternary amines, and that the nitrosamines form from the quaternary amines themselves, not just lower order amine impurities. Polymeric and benzylated quaternary amines were more potent precursors than monomeric quaternary alkylamines. Pretreatment of quaternary amines with ozone or free chlorine, which deactivate lower order amine impurities, did not significantly reduce nitrosamine formation. The nitrosamine formation pathway is unclear but experiments indicated that transformation of quaternary amines to lower order amine precursors via Hofmann elimination was not involved. Experiments suggest that the pathway may involve quaternary amine degradation by amidogen or chloramino radicals formed from chloramines. Quaternary amines are significant constituents of consumer products, including shampoos, detergents, and fabric softeners. Although quaternary amines may be removed by sedimentation during wastewater treatment, their importance should be evaluated on a case-by-case basis. The high loadings from consumer products may enable the portion not removed to serve as precursors. PMID:20085252

  15. Quaternary Geologic Map of Connecticut and Long Island Sound Basin

    USGS Publications Warehouse

    Stone, Janet Radway; Schafer, John P.; London, Elizabeth Haley; DiGiacomo-Cohen, Mary L.; Lewis, Ralph S.; Thompson, Woodrow B.

    2005-01-01

    The Quaternary geologic map (sheet 1) and explanatory figures and cross sections (sheet 2) portray the geologic features formed in Connecticut during the Quaternary Period, which includes the Pleistocene (glacial) and Holocene (postglacial) Epochs. The Quaternary Period has been a time of development of many details of the landscape and of all the surficial deposits. At least twice in the late Pleistocene, continental ice sheets swept across Connecticut. Their effects are of pervasive importance to the present occupants of the land. The Quaternary geologic map illustrates the geologic history and the distribution of depositional environments during the emplacement of glacial and postglacial surficial deposits and the landforms resulting from those events.

  16. Shifting Sediment Sources in the Quaternary Nile

    NASA Astrophysics Data System (ADS)

    Woodward, Jamie; Macklin, Mark; Fielding, Laura; Millar, Ian; Williams, Martin

    2016-04-01

    Invited Paper The Nile basin contains the longest river channel system in the world and drains about one tenth of the African continent. A dominant characteristic of the modern Nile is the marked spatial and temporal variability in the flux of water and sediment. Because the major headwater basins of the Nile are linked to key elements of the global climate system, the sedimentary records in the basin have attracted good deal of attention from the Quaternary palaeoclimate and palaeohydrology communities. Various approaches (from heavy minerals to strontium isotopes) have been employed to examine present and past patterns of sediment yield in the basin. A good deal of work has been carried out on the long sediment records in the delta and offshore which provide high resolution archives of hydrological changes in the upstream basin as well fluctuations in the input of dust from the desert. The sediment load of the modern desert Nile (downstream of Khartoum) is dominated by sediment inputs from the Blue Nile (61 +/- 5%) and Atbara (35 +/- 4%), whilst the White Nile contribution is meagre (3 +/- 2%) (Padoan et al. 2011). Recent work has shown that these values were very different during humid phases of the Quaternary when stronger Northern Hemisphere summer insolation produced wetter conditions across North Africa. In the early Holocene, for example, the Nile floodplain in Northern Sudan shows a tributary wadi input of 40-50%. This paper will review three decades of work on the sediment delivery dynamics of the Quaternary Nile and explore their palaeoclimatic implications. Padoan, M., Garzanti, E., Harlavan, Y., Villa, I.M. (2011) Tracing Nile sediment sources by Sr and Nd isotope signatures (Uganda, Ethiopia, Sudan). Geochim. Cosmochim. Acta 75 (12), 3627-3644.

  17. Late Quaternary history of southern Chesapeake Bay

    SciTech Connect

    Colman, S.M.; Hobbs, C.H. III; Halka, J.P.

    1985-01-01

    More than 700 km of high-resolution, seismic-reflection profiles and sidescan-sonar images provide new information about the late Quaternary history of southern Chesapeake Bay. Sidescan-sonar images show that, excluding the nearshore zone, most of the bay bottom has a monotonously smooth surface, except that sand waves, ripples, and other bedforms occur in local areas affected by tidal currents. Seismic-reflection data show that the Quaternary stratigraphy of the southern part of the Bay is related primarily to the last cycle of sea-level change. The Quaternary section overlies an erosion surface cut deeply into gently seaward-dipping marine beds of Neogene age. Fluvial paleochannels, related to the last major low sea-level stand, are characterized by as much as 55 m of incision and by thin, irregular, terrace and channel-bottom deposits. Marine and estuarine deposits related to the Holocene transgression partially or fully bury the fluvial valleys and overlie the interfluves. A prominent feature of the Bay-mouth area is a wedge of sediment that has prograded into the Bay from the inner shelf. The common assumption--that the Chesapeake Bay is the drowned valley of the Pleistocene Susquehanna River--is only partially valid for the southern part of the Bay. The Bay mouth area, in general, is relatively young. The axial channel of the Bay is a modern tidal channel that is actively eroding Tertiary deposits and migrating toward the south and west; it is unrelated to older fluvial channels. Also, the positions of the modern axial channel and the last two fluvial paleochannels indicate long-term southward migration of the Bay mouth.

  18. Quaternary vertebrates from Greenland: A review

    NASA Astrophysics Data System (ADS)

    Bennike, Ole

    Remains of fishes, birds and mammals are rarely reported from Quaternary deposits in Greenland. The oldest remains come from Late Pliocene and Early Pleistocene deposits and comprise Atlantic cod, hare, rabbit and ringed seal. Interglacial and interstadial deposits have yielded remains of cod, little auk, collared lemming, ringed seal, reindeer and bowhead whale. Early and Mid-Holocene finds include capelin, polar cod, red fish, sculpin, three-spined stickleback, Lapland longspur, Arctic hare, collared lemming, wolf, walrus, ringed seal, reindeer and bowhead whale. It is considered unlikely that vertebrates could survive in Greenland during the peak of the last glaciation, but many species had probably already immigrated in the Early Holocene.

  19. 21 CFR 172.165 - Quaternary ammonium chloride combination.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HUMAN CONSUMPTION Food Preservatives § 172.165 Quaternary ammonium chloride combination. The food... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Quaternary ammonium chloride combination. 172.165 Section 172.165 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  20. 40 CFR 721.10582 - Quaternary ammonium compound (generic).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Quaternary ammonium compound (generic... Specific Chemical Substances § 721.10582 Quaternary ammonium compound (generic). (a) Chemical substance and... ammonium compound (PMN P-10-571) is subject to reporting under this section for the significant new...

  1. 40 CFR 721.10582 - Quaternary ammonium compound (generic).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Quaternary ammonium compound (generic... Specific Chemical Substances § 721.10582 Quaternary ammonium compound (generic). (a) Chemical substance and... ammonium compound (PMN P-10-571) is subject to reporting under this section for the significant new...

  2. 40 CFR 721.10511 - Quaternary ammonium salts (generic).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Quaternary ammonium salts (generic... Specific Chemical Substances § 721.10511 Quaternary ammonium salts (generic). (a) Chemical substance and... ammonium salts (PMNs P-07-320, P-07-321, P-07-322, P-07-323, and P-07-324) are subject to reporting...

  3. 40 CFR 721.10511 - Quaternary ammonium salts (generic).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Quaternary ammonium salts (generic... Specific Chemical Substances § 721.10511 Quaternary ammonium salts (generic). (a) Chemical substance and... ammonium salts (PMNs P-07-320, P-07-321, P-07-322, P-07-323, and P-07-324) are subject to reporting...

  4. 21 CFR 172.165 - Quaternary ammonium chloride combination.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... HUMAN CONSUMPTION Food Preservatives § 172.165 Quaternary ammonium chloride combination. The food... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Quaternary ammonium chloride combination. 172.165 Section 172.165 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  5. 21 CFR 172.165 - Quaternary ammonium chloride combination.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... HUMAN CONSUMPTION Food Preservatives § 172.165 Quaternary ammonium chloride combination. The food... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Quaternary ammonium chloride combination. 172.165 Section 172.165 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  6. 21 CFR 172.165 - Quaternary ammonium chloride combination.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... HUMAN CONSUMPTION Food Preservatives § 172.165 Quaternary ammonium chloride combination. The food... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Quaternary ammonium chloride combination. 172.165 Section 172.165 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  7. Late Quaternary climate change shapes island biodiversity.

    PubMed

    Weigelt, Patrick; Steinbauer, Manuel Jonas; Cabral, Juliano Sarmento; Kreft, Holger

    2016-04-01

    Island biogeographical models consider islands either as geologically static with biodiversity resulting from ecologically neutral immigration-extinction dynamics, or as geologically dynamic with biodiversity resulting from immigration-speciation-extinction dynamics influenced by changes in island characteristics over millions of years. Present climate and spatial arrangement of islands, however, are rather exceptional compared to most of the Late Quaternary, which is characterized by recurrent cooler and drier glacial periods. These climatic oscillations over short geological timescales strongly affected sea levels and caused massive changes in island area, isolation and connectivity, orders of magnitude faster than the geological processes of island formation, subsidence and erosion considered in island theory. Consequences of these oscillations for present biodiversity remain unassessed. Here we analyse the effects of present and Last Glacial Maximum (LGM) island area, isolation, elevation and climate on key components of angiosperm diversity on islands worldwide. We find that post-LGM changes in island characteristics, especially in area, have left a strong imprint on present diversity of endemic species. Specifically, the number and proportion of endemic species today is significantly higher on islands that were larger during the LGM. Native species richness, in turn, is mostly determined by present island characteristics. We conclude that an appreciation of Late Quaternary environmental change is essential to understand patterns of island endemism and its underlying evolutionary dynamics. PMID:27027291

  8. Late Quaternary climate change shapes island biodiversity.

    PubMed

    Weigelt, Patrick; Steinbauer, Manuel Jonas; Cabral, Juliano Sarmento; Kreft, Holger

    2016-04-01

    Island biogeographical models consider islands either as geologically static with biodiversity resulting from ecologically neutral immigration-extinction dynamics, or as geologically dynamic with biodiversity resulting from immigration-speciation-extinction dynamics influenced by changes in island characteristics over millions of years. Present climate and spatial arrangement of islands, however, are rather exceptional compared to most of the Late Quaternary, which is characterized by recurrent cooler and drier glacial periods. These climatic oscillations over short geological timescales strongly affected sea levels and caused massive changes in island area, isolation and connectivity, orders of magnitude faster than the geological processes of island formation, subsidence and erosion considered in island theory. Consequences of these oscillations for present biodiversity remain unassessed. Here we analyse the effects of present and Last Glacial Maximum (LGM) island area, isolation, elevation and climate on key components of angiosperm diversity on islands worldwide. We find that post-LGM changes in island characteristics, especially in area, have left a strong imprint on present diversity of endemic species. Specifically, the number and proportion of endemic species today is significantly higher on islands that were larger during the LGM. Native species richness, in turn, is mostly determined by present island characteristics. We conclude that an appreciation of Late Quaternary environmental change is essential to understand patterns of island endemism and its underlying evolutionary dynamics.

  9. Synergistically enhanced activity of graphene quantum dots/graphene hydrogel composites: a novel all-carbon hybrid electrocatalyst for metal/air batteries

    NASA Astrophysics Data System (ADS)

    Wang, Mengran; Fang, Zhao; Zhang, Kai; Fang, Jing; Qin, Furong; Zhang, Zhian; Li, Jie; Liu, Yexiang; Lai, Yanqing

    2016-06-01

    Primary zinc/air batteries could be the next generation of energy storage devices because of their high power density and high safety. Graphene quantum dots nested in the graphene hydrogel have been proposed as excellent all-carbon hybrid oxygen reduction reaction (ORR) catalysts, indicative of their great potential in primary zinc/air batteries.Primary zinc/air batteries could be the next generation of energy storage devices because of their high power density and high safety. Graphene quantum dots nested in the graphene hydrogel have been proposed as excellent all-carbon hybrid oxygen reduction reaction (ORR) catalysts, indicative of their great potential in primary zinc/air batteries. Electronic supplementary information (ESI) available. See DOI: 10.1039/c6nr02622b

  10. Am(III) and Eu(III) extraction by substituted quaternary ammonium salts

    SciTech Connect

    Chiarizia, R.; Gatrone, R.C.; Horwitz, E.P.

    1995-12-01

    The extraction of Am(III) and Eu(III) from HNO{sub 3}-LiNO{sub 3} or from HCOOH-NH{sub 4}SCN solutions by different quaternary ammonium salts dissolved in o-xylene was investigated as function of the aqueous phase composition. As extractants, the nitrate or thiocyanate salts of Aliquat{sm_bullet}336, tridodecylmethylammonium, benzyldimethyldodecylammonium, p-methoxybenzyldimethyidodecylammonium and p-trifluoromethylbenzyldimethyldodecylammonium were used. The extraction data were interpreted by a reaction scheme that takes into account the aqueous metal complexation and the competition between aqueous acid and metal species for the extractant reaction center. The effect of the benzyl group (whether substituted or not) on the metal and acid extraction by the different quaternary ammonium salts was interpreted on the basis of the inductive effect of the substituents. In the thiocyanate system, Aliquat{sm_bullet}336 provided the highest Am/Eu separation factors. In the nitrate system, the highest Am/Eu separation factors were exhibited by the benzyl substituted quaternary ammonium salts.

  11. Ultrafast electron transfer in all-carbon-based SWCNT-C60 donor-acceptor nanoensembles connected by poly(phenylene-ethynylene) spacers.

    PubMed

    Barrejón, Myriam; Gobeze, Habtom B; Gómez-Escalonilla, María J; Fierro, José Luis G; Zhang, Minfang; Yudasaka, Masako; Iijima, Sumio; D'Souza, Francis; Langa, Fernando

    2016-08-21

    Building all-carbon based functional materials for light energy harvesting applications could be a solution to tackle and reduce environmental carbon output. However, development of such all-carbon based donor-acceptor hybrids and demonstration of photoinduced charge separation in such nanohybrids is a challenge since in these hybrids part of the carbon material should act as an electron donating or accepting photosensitizer while the second part should fulfil the role of an electron acceptor or donor. In the present work, we have successfully addressed this issue by synthesizing covalently linked all-carbon-based donor-acceptor nanoensembles using single-walled carbon nanotubes (SWCNTs) as the donor and C60 as the acceptor. The donor-acceptor entities in the nanoensembles were connected by phenylene-ethynylene spacer units to achieve better electronic communication and to vary the distance between the components. These novel SWCNT-C60 nanoensembles have been characterized by a number of techniques, including TGA, FT-IR, Raman, AFM, absorbance and electrochemical methods. The moderate number of fullerene addends present on the side-walls of the nanotubes largely preserved the electronic structure of the nanotubes. The thermodynamic feasibility of charge separation in these nanoensembles was established using spectral and electrochemical data. Finally, occurrence of ultrafast electron transfer from the excited nanotubes in these donor-acceptor nanohybrids has been established by femtosecond transient absorption studies, signifying their utility in building light energy harvesting devices.

  12. Ultrafast electron transfer in all-carbon-based SWCNT-C60 donor-acceptor nanoensembles connected by poly(phenylene-ethynylene) spacers.

    PubMed

    Barrejón, Myriam; Gobeze, Habtom B; Gómez-Escalonilla, María J; Fierro, José Luis G; Zhang, Minfang; Yudasaka, Masako; Iijima, Sumio; D'Souza, Francis; Langa, Fernando

    2016-08-21

    Building all-carbon based functional materials for light energy harvesting applications could be a solution to tackle and reduce environmental carbon output. However, development of such all-carbon based donor-acceptor hybrids and demonstration of photoinduced charge separation in such nanohybrids is a challenge since in these hybrids part of the carbon material should act as an electron donating or accepting photosensitizer while the second part should fulfil the role of an electron acceptor or donor. In the present work, we have successfully addressed this issue by synthesizing covalently linked all-carbon-based donor-acceptor nanoensembles using single-walled carbon nanotubes (SWCNTs) as the donor and C60 as the acceptor. The donor-acceptor entities in the nanoensembles were connected by phenylene-ethynylene spacer units to achieve better electronic communication and to vary the distance between the components. These novel SWCNT-C60 nanoensembles have been characterized by a number of techniques, including TGA, FT-IR, Raman, AFM, absorbance and electrochemical methods. The moderate number of fullerene addends present on the side-walls of the nanotubes largely preserved the electronic structure of the nanotubes. The thermodynamic feasibility of charge separation in these nanoensembles was established using spectral and electrochemical data. Finally, occurrence of ultrafast electron transfer from the excited nanotubes in these donor-acceptor nanohybrids has been established by femtosecond transient absorption studies, signifying their utility in building light energy harvesting devices. PMID:27305145

  13. Latest quaternary volcanism in the St. George Basin, southwestern Utah

    SciTech Connect

    Millings, V.T. III; Green, J.D.; Nusbaum, R.L. . Dept. of Geology)

    1993-03-01

    The St. George Basin was the site of mafic volcanism from about 6 Ma to 1 ka. The nature of latest Quaternary volcanism is of interest because the Basin is recognized as a low temperature (< 90C) geothermal resource area and it is part of the transition zone between the Basin and Range Province and the Colorado Plateau. The authors have studied the geochemistry, mineralogy, and aerial distribution of two of the youngest eruptions centers: (1) Veyo Volcano; and (2) the Diamond Valley scoria cones (DVSC). Veyo Volcano erupted basaltic andesite, beginning with an explosive stage marked by a 0.5 m basal Plinian layer. Later eruptions alternated between quiescent and Strombolian-styles. Phenocrysts include clear plagioclase, sieve-texture plagioclase, olivine and rare augite. The DVSC and associated Santa Clara lava flow are tholeiitic basalt, consisting of olivine phenocrysts, and rare plagioclase phenocrysts. Based on preliminary geochemical data, Diamond Valley rocks exhibit lower incompatible element ratios compared to mafic rocks on the Markagunt Plateau and transition zone rocks. In contrast, Veyo Volcano rocks are similar to transition zone mafic rocks with regard to incompatible element abundances.

  14. Radiolysis of simple quaternary ammonium salt components of Amberlite resin

    NASA Astrophysics Data System (ADS)

    Dhiman, Surajdevprakash B.; LaVerne, Jay A.

    2013-05-01

    The radiation chemical yields of gaseous products, H2 and CH4, in the radiolysis of dry methylammonium chloride, dimethylammonium chloride, trimethylammonium chloride, tetramethylammonium chloride and benzyl trimethylammonium chloride by γ-rays and 5 MeV helium ions have been investigated. Some of these amines are the different components of the quaternary ammonium resin Amberlite, which is a strongly basic anion exchange resin based on a polystyrene divinylbenzene copolymer. Molecular hydrogen yields with γ-radiolysis range from a high of 4.43 molecules per 100 eV for trimethylammonium chloride to 0.07 and 0.05 molecules per 100 eV for tetramethylammonium chloride and benzyl trimethylammonium chloride, respectively. Yields of methane gas are generally negligible except for trimethylammonium chloride and tetramethylammonium chloride, 0.26 and 0.02 molecules per 100 eV, respectively. Isotopic labeling studies suggest that the first step in H2 production is the breakage of the Nsbnd H bond followed by abstraction of Hrad atom from the methyl groups. EPR analysis shows the formation of both N and C centered radicals. A comparison is made between the radiolysis of Amberlite and its various components.

  15. Survey of Portions of the Chromium-Cobalt-Nickel-Molybdenum Quaternary System at 1,200 Degrees C

    NASA Technical Reports Server (NTRS)

    Rideout, Sheldon Paul; Beck, Paul A

    1953-01-01

    A survey was made of portions of the chromium-cobalt-nickel-molybdenum quaternary system at 1,200 degrees c by means of microscopic and x-ray diffraction studies. Since the face-centered cubic (alpha) solid solutions form the matrix of almost all practically useful high-temperature alloys, the solid solubility limits of the quaternary alpha phase were determined up to 20 percent molybdenum. The component cobalt-nickel-molybdenum, chromium-cobalt-molybdenum, and chromium-nickel-molybdenum ternary systems were also studied. The survey of these systems was confined to the determination of the boundaries of the face-centered cubic (alpha) solid solutions and of the phases coexisting with alpha at 1,200 degrees c.

  16. Dual Catalysis Using Boronic Acid and Chiral Amine: Acyclic Quaternary Carbons via Enantioselective Alkylation of Branched Aldehydes with Allylic Alcohols.

    PubMed

    Mo, Xiaobin; Hall, Dennis G

    2016-08-31

    A ferrocenium boronic acid salt activates allylic alcohols to generate transient carbocations that react with in situ-generated chiral enamines from branched aldehydes. The optimized conditions afford the desired acyclic products embedding a methyl-aryl quaternary carbon center with up to 90% yield and 97:3 enantiomeric ratio, with only water as the byproduct. This noble-metal-free method complements alternative methods that are incompatible with carbon-halogen bonds and other sensitive functional groups. PMID:27518200

  17. Quaternary coral reef refugia preserved fish diversity.

    PubMed

    Pellissier, Loïc; Leprieur, Fabien; Parravicini, Valeriano; Cowman, Peter F; Kulbicki, Michel; Litsios, Glenn; Olsen, Steffen M; Wisz, Mary S; Bellwood, David R; Mouillot, David

    2014-05-30

    The most prominent pattern in global marine biogeography is the biodiversity peak in the Indo-Australian Archipelago. Yet the processes that underpin this pattern are still actively debated. By reconstructing global marine paleoenvironments over the past 3 million years on the basis of sediment cores, we assessed the extent to which Quaternary climate fluctuations can explain global variation in current reef fish richness. Comparing global historical coral reef habitat availability with the present-day distribution of 6316 reef fish species, we find that distance from stable coral reef habitats during historical periods of habitat loss explains 62% of the variation in fish richness, outweighing present-day environmental factors. Our results highlight the importance of habitat persistence during periods of climate change for preserving marine biodiversity. PMID:24876495

  18. [Quaternary ammonium compounds--new occupational hazards].

    PubMed

    Lipińska-Ojrzanowska, Agnieszka; Walusiak-Skorupa, Jolanta

    2014-01-01

    Quaternary ammonium compounds (QACs, quats) belong to organic ionic chemical agents which display unique properties of both surfactants and disinfectants. Their wide distribution in the work environment and also in private households brings about new occupational hazards. This paper reviews reports about the health effects of QACs. QACs could play a role of sensitizers and irritants to the skin and mucous membranes. It is suspected that particular QACs can display an immunologic cross-reactivity between each other and with other chemical compounds containing ammonium ion, such as muscle relaxants widely used in anesthesia. They may promote the development of airway allergy, however, the background mechanisms are still unclear and need to be further investigated. Until now, a few cases of occupational asthma induced by QACs have been described and their involvement in contact dermatitis has been documented. The possibility of anaphylaxis due to QACs cannot be excluded as well. PMID:25812396

  19. Suggested terminology for Quaternary dating methods

    USGS Publications Warehouse

    Colman, Steven M.; Pierce, K.L.; Birkeland, P.W.

    1987-01-01

    Classification of Quaternary dating methods should be based on the level of quantitative information and the degree of confidence contained in the age estimates produced by the dating methods. We recommend the use of the terms numerical-age, calibrated-age, relative-age, and correlated-age to describe these levels. We also classify dating methods by type into sideral, isotopic, radiogenic, chemical and biological, geomorphic, and correlation methods. The use of "absolute" is inappropriate for most dating methods, and should be replaced by "numerical." The use of "date" should be minimized in favor of "age" or "age estimate." We recommend use of the abbreviations ka and Ma for most ages; calender dates can be used where appropriate and yr B.P. can be used for radiocarbon ages. ?? 1987.

  20. Quaternary geology of Avery Island, Louisiana

    SciTech Connect

    Autin, W.J.; McCulloh, R.P.; Davison, A.T.

    1986-09-01

    Avery Island, one of the Five Islands salt domes of south-central Louisiana, is a piercement-type dome that has been uplifted from several kilometers' depth. It is nearly circular in plan with a maximum elevation approximately 50 m above the surrounding coastal marsh. Dissection has produced a terrain of gullies and steep slopes. The features identified indicate a complex geologic history for Avery Island. Deposition of late Pleistocene sediments in a low-relief alluvial plain and subsequent soil development predate domal uplift. The stratigraphy of loess and colluvial silts indicates the island was emergent during loess depositions. The degree of dissection, distribution of colluvium, and shearing of Quaternary sediments reflects continual uplift after loess deposition.

  1. Antimicrobial Polymeric Materials with Quaternary Ammonium and Phosphonium Salts

    PubMed Central

    Xue, Yan; Xiao, Huining; Zhang, Yi

    2015-01-01

    Polymeric materials containing quaternary ammonium and/or phosphonium salts have been extensively studied and applied to a variety of antimicrobial-relevant areas. With various architectures, polymeric quaternary ammonium/phosphonium salts were prepared using different approaches, exhibiting different antimicrobial activities and potential applications. This review focuses on the state of the art of antimicrobial polymers with quaternary ammonium/phosphonium salts. In particular, it discusses the structure and synthesis method, mechanisms of antimicrobial action, and the comparison of antimicrobial performance between these two kinds of polymers. PMID:25667977

  2. Ultrafast electron transfer in all-carbon-based SWCNT-C60 donor-acceptor nanoensembles connected by poly(phenylene-ethynylene) spacers

    NASA Astrophysics Data System (ADS)

    Barrejón, Myriam; Gobeze, Habtom B.; Gómez-Escalonilla, María J.; Fierro, José Luis G.; Zhang, Minfang; Yudasaka, Masako; Iijima, Sumio; D'Souza, Francis; Langa, Fernando

    2016-08-01

    Building all-carbon based functional materials for light energy harvesting applications could be a solution to tackle and reduce environmental carbon output. However, development of such all-carbon based donor-acceptor hybrids and demonstration of photoinduced charge separation in such nanohybrids is a challenge since in these hybrids part of the carbon material should act as an electron donating or accepting photosensitizer while the second part should fulfil the role of an electron acceptor or donor. In the present work, we have successfully addressed this issue by synthesizing covalently linked all-carbon-based donor-acceptor nanoensembles using single-walled carbon nanotubes (SWCNTs) as the donor and C60 as the acceptor. The donor-acceptor entities in the nanoensembles were connected by phenylene-ethynylene spacer units to achieve better electronic communication and to vary the distance between the components. These novel SWCNT-C60 nanoensembles have been characterized by a number of techniques, including TGA, FT-IR, Raman, AFM, absorbance and electrochemical methods. The moderate number of fullerene addends present on the side-walls of the nanotubes largely preserved the electronic structure of the nanotubes. The thermodynamic feasibility of charge separation in these nanoensembles was established using spectral and electrochemical data. Finally, occurrence of ultrafast electron transfer from the excited nanotubes in these donor-acceptor nanohybrids has been established by femtosecond transient absorption studies, signifying their utility in building light energy harvesting devices.Building all-carbon based functional materials for light energy harvesting applications could be a solution to tackle and reduce environmental carbon output. However, development of such all-carbon based donor-acceptor hybrids and demonstration of photoinduced charge separation in such nanohybrids is a challenge since in these hybrids part of the carbon material should act as an

  3. A Quaternary Geomagnetic Instability Time Scale

    NASA Astrophysics Data System (ADS)

    Singer, B. S.

    2013-12-01

    Reversals and excursions of Earth's geomagnetic field create marker horizons that are readily detected in sedimentary and volcanic rocks worldwide. An accurate and precise chronology of these geomagnetic field instabilities is fundamental to understanding several aspects of Quaternary climate, dynamo processes, and surface processes. For example, stratigraphic correlation between marine sediment and polar ice records of climate change across the cryospheres benefits from a highly resolved record of reversals and excursions. The temporal patterns of dynamo behavior may reflect physical interactions between the molten outer core and the solid inner core or lowermost mantle. These interactions may control reversal frequency and shape the weak magnetic fields that arise during successive dynamo instabilities. Moreover, weakening of the axial dipole during reversals and excursions enhances the production of cosmogenic isotopes that are used in sediment and ice core stratigraphy and surface exposure dating. The Geomagnetic Instability Time Scale (GITS) is based on the direct dating of transitional polarity states recorded by lava flows using the 40Ar/39Ar method, in parallel with astrochronologic age models of marine sediments in which O isotope and magnetic records have been obtained. A review of data from Quaternary lava flows and sediments yields a GITS comprising 10 polarity reversals and 27 excursions during the past 2.6 million years. Nine of the ten reversals bounding chrons and subchrons are associated with 40Ar/39Ar ages of transitionally-magnetized lava flows. The tenth, the Guass-Matuyama chron boundary, is tightly bracketed by 40Ar/39Ar dated ash deposits. Of the 27 well-documented excursions, 14 occurred during the Matuyama chron and 13 during the Brunhes chron; 19 have been dated directly using the 40Ar/39Ar method on transitionally-magnetized volcanic rocks and form the backbone of the GITS. Excursions are clearly not the rare phenomena once thought

  4. Experimental investigation into Quaternary badland geomorphic development

    NASA Astrophysics Data System (ADS)

    Kasanin-Grubin, Milica; Kuhn, Nikolaus; Yair, Aaron; Bryan, Rorke; Schwanghart, Wolfgang

    2010-05-01

    Badland morphology is commonly linked to lithological properties of the bedrock. However, recent investigations indicate that the geomorphic development is sensitive to climate and in particular to precipitation characteristics. In this study, the precipitation characteristics that are critical for the Quaternary landscape development in the Dinosaur Badlands in Alberta, Canada, and Zin Valley Badlands, Negev Desert, Israel are investigated. Runoff, erosion and weathering were simulated in the field and the laboratory to determine rates for modeling different precipitation regimes. Currently, the geomorphic development in the Dinosaur badlands is characterized by weathering/supply limited conditions, leading to slope retreat independent of lithology. In the Negev, transport limited conditions cause frequent runoff discontinuity, creating a pattern of areas dominated by erosion or deposition. The results of the weathering and erosion experiments show that the balance between snowmelt induced weathering in the spring and summer rainfall and erosion determine the rate of slope retreat in the Dinosaur Badlands. In the Zin Valley, on the other hand, the magnitude of the individual rainstorms determines whether a slope section is eroded or acts as a sediment sink. The experiments illustrate that the badland slopes experienced an auto-stabilization during the Quaternary in the Zin Valley. In the Dinosaur Badlands Holocene climatic variations have not caused a permanent differentiation of patterns of erosion and deposition. Based on these results the reaction of badland slopes to changing precipitation characteristics was modeled. In their current state, both badland slope systems appear to be fairly stable against climate change in the range of those occurring during the Holocene. However, the stability is achieved in different ways. In the Dinosaur Badlands, weathering rates are low compared to erosion capacity, maintaining continuous evacuation of sediment from slopes

  5. Known and suggested quaternary faulting in the midcontinent United States

    USGS Publications Warehouse

    Wheeler, R.L.; Crone, A.J.

    2001-01-01

    The midcontinent United States between the Appalachian and Rocky Mountains contains 40 known faults or other potentially tectonic features for which published geologic information shows or suggests Quaternary tectonic faulting. We report results of a systematic evaluation of published and other publicly available geologic evidence of Quaternary faulting. These results benefit seismic-hazard assessments by (1) providing some constraints on the recurrence intervals and magnitudes of large, prehistoric earthquakes, and (2) identifying features that warrant additional study. For some features, suggested Quaternary tectonic faulting has been disproved, whereas, for others, the suggested faulting remains questionable. Of the 40 features, nine have clear geologic evidence of Quaternary tectonic faulting associated with prehistoric earthquakes, and another six features have evidence of nontectonic origins. An additional 12 faults, uplifts, or historical seismic zones lack reported paleoseismological evidence of large. Quaternary earthquakes. The remaining 13 features require further paleoseismological study to determine if they have had Quaternary earthquakes that were larger than any known from local historical records; seven of these 13 features are in or near urbanized areas where their study could affect urban hazard estimates. These seven are: (1) the belt of normal faults that rings the Gulf of Mexico from Florida to Texas. (2) the Northeast Ohio seismic zone, (3) the Valmont and (4) Goodpasture faults of Colorado. (5) the Champlain lowlands normal faults of New York State and Vermont, and (6) the Lexington and (7) Kentucky River fault systems of eastern Kentucky. Published by Elsevier Science B.V.

  6. A Quaternary Fault Database for Central Asia

    NASA Astrophysics Data System (ADS)

    Mohadjer, S.; Ehlers, T. A.; Bendick, R.; Stübner, K.; Strube, T.

    2015-09-01

    Earthquakes represent the highest risk in terms of potential loss of lives and economic damage for Central Asian countries. Knowledge of fault location and behavior is essential in calculating and mapping seismic hazard. Previous efforts in compiling fault information for Central Asia have generated a large amount of data that are published in limited-access journals with no digital maps publicly available, or are limited in their description of important fault parameters such as slip rates. This study builds on previous work by improving access to fault information through a web-based interactive map and an online database with search capabilities that allow users to organize data by different fields. The data presented in this compilation include fault location, its geographic, seismic and structural characteristics, short descriptions, narrative comments and references to peer-reviewed publications. The interactive map displays 1196 fault segments and 34 000 earthquake locations on a shaded-relief map. The online database contains attributes for 122 faults mentioned in the literature, with Quaternary and geodetic slip rates reported for 38 and 26 faults respectively, and earthquake history reported for 39 faults. This work has implications for seismic hazard studies in Central Asia as it summarizes important fault parameters, and can reduce earthquake risk by enhancing public access to information. It also allows scientists and hazard assessment teams to identify structures and regions where data gaps exist and future investigations are needed.

  7. (Model) Peatlands in late Quaternary interglacials

    NASA Astrophysics Data System (ADS)

    Kleinen, Thomas; Brovkin, Victor

    2016-04-01

    Peatlands have accumulated a substantial amount of carbon, roughly 600 PgC, during the Holocene. Prior to the Holocene, there is relatively little direct evidence of peatlands, though coal deposits bear witness to a long history of peat-forming ecosystems going back to the Carboniferous. We therefore need to rely on models to investigate peatlands in times prior to the Holocene. We have developed a dynamical model of wetland extent and peat accumulation, integrated in the coupled climate carbon cycle model of intermediate complexity CLIMBER2-LPJ, in order to mechanistically model interglacial carbon cycle dynamics. This model consists of the climate model of intermediate complexity CLIMBER2 and the dynamic global vegetation model LPJ, which we have extended with modules to determine peatland extent and carbon accumulation. The model compares reasonably well to Holocene peat data. We have used this model to investigate the dynamics of atmospheric CO2 in the Holocene and two other late Quaternary interglacials, namely the Eemian, which is interesting due to its warmth, and Marine Isotope Stage 11 (MIS11), which is the longest interglacial during the last 500ka. We will also present model results of peatland extent and carbon accumulation for these interglacials. We will discuss model shortcomings and knowledge gaps currently preventing an application of the model to full glacial-interglacial cycles.

  8. Late Quaternary mammalian zoogeography of eastern Washington

    NASA Astrophysics Data System (ADS)

    Lyman, R. Lee; Livingston, Stephanie D.

    1983-11-01

    The late Quaternary mammalian zoogeographic history of eastern Washington as revealed by archaeological and paleontological research conforms to a set of past environmental conditions inferred from botanical data. During the relatively cool and moist late Pleistocene and early Holocene, Cervus cf. elaphus, Ovis canadensis, Vulpes vulpes, Martes americana, Alopex lagopus, and perhaps Rangifer sp., taxa with ecological preferences for mesic steppe habitats, were present in the now xeric Columbia Basin. As the climate became progressively warmer and drier during the late Pleistocene and early Holocene, Antilocapra americana, Onychomys leucogaster, Spermophilus townsendii, and Neotoma cinerea, taxa with ecological preferences for xeric steppe habitats, appear in the Columbia Basin. Bison sp. and Taxidea taxus may have been present in eastern Washington for the last 20,000 yr. Middle and late Holocene records for Oreamnos americanus, Spermophilus columbianus, S. townsendii, Lagurus curtatus, and Urocyon cinereoargenteus in central eastern Washington suggest fluctuations in the ranges of these taxa that conform to a middle Holocene period of less effective precipitation and a ca. 3500-yr-old period of more effective precipitation before essentially modern environmental conditions prevailed.

  9. Late Quaternary history of the Atacama Desert

    USGS Publications Warehouse

    Latorre, Claudio; Betancourt, Julio L.; Rech, Jason A.; Quade, Jay; Holmgren, Camille; Placzek, Christa; Maldonado, Antonio; Vuille, Mathias; Rylander, Kate A.; Smith, Mike; Hesse, Paul

    2005-01-01

    Of the major subtropical deserts found in the Southern Hemisphere, the Atacama Desert is the driest. Throughout the Quaternary, the most pervasive climatic influence on the desert has been millennial-scale changes in the frequency and seasonality of the scant rainfall, and associated shifts in plant and animal distributions with elevation along the eastern margin of the desert. Over the past six years, we have mapped modern vegetation gradients and developed a number of palaeoenvironmental records, including vegetation histories from fossil rodent middens, groundwater levels from wetland (spring) deposits, and lake levels from shoreline evidence, along a 1200-kilometre transect (16–26°S) in the Atacama Desert. A strength of this palaeoclimate transect has been the ability to apply the same methodologies across broad elevational, latitudinal, climatic, vegetation and hydrological gradients. We are using this transect to reconstruct the histories of key components of the South American tropical (summer) and extratropical (winter) rainfall belts, precisely at those elevations where average annual rainfall wanes to zero. The focus has been on the transition from sparse, shrubby vegetation (known as the prepuna) into absolute desert, an expansive hyperarid terrain that extends from just above the coastal fog zone (approximately 800 metres) to more than 3500 metres in the most arid sectors in the southern Atacama.

  10. Quaternary Ammonium Biocides: Efficacy in Application

    PubMed Central

    2014-01-01

    Quaternary ammonium compounds (QACs) are among the most commonly used disinfectants. There has been concern that their widespread use will lead to the development of resistant organisms, and it has been suggested that limits should be place on their use. While increases in tolerance to QACs have been observed, there is no clear evidence to support the development of resistance to QACs. Since efflux pumps are believe to account for at least some of the increased tolerance found in bacteria, there has been concern that this will enhance the resistance of bacteria to certain antibiotics. QACs are membrane-active agents interacting with the cytoplasmic membrane of bacteria and lipids of viruses. The wide variety of chemical structures possible has seen an evolution in their effectiveness and expansion of applications over the last century, including non-lipid-containing viruses (i.e., noroviruses). Selection of formulations and methods of application have been shown to affect the efficacy of QACs. While numerous laboratory studies on the efficacy of QACs are available, relatively few studies have been conducted to assess their efficacy in practice. Better standardized tests for assessing and defining the differences between increases in tolerance versus resistance are needed. The ecological dynamics of microbial communities where QACs are a main line of defense against exposure to pathogens need to be better understood in terms of sublethal doses and antibiotic resistance. PMID:25362069

  11. A Quaternary fault database for central Asia

    NASA Astrophysics Data System (ADS)

    Mohadjer, Solmaz; Ehlers, Todd Alan; Bendick, Rebecca; Stübner, Konstanze; Strube, Timo

    2016-02-01

    Earthquakes represent the highest risk in terms of potential loss of lives and economic damage for central Asian countries. Knowledge of fault location and behavior is essential in calculating and mapping seismic hazard. Previous efforts in compiling fault information for central Asia have generated a large amount of data that are published in limited-access journals with no digital maps publicly available, or are limited in their description of important fault parameters such as slip rates. This study builds on previous work by improving access to fault information through a web-based interactive map and an online database with search capabilities that allow users to organize data by different fields. The data presented in this compilation include fault location, its geographic, seismic, and structural characteristics, short descriptions, narrative comments, and references to peer-reviewed publications. The interactive map displays 1196 fault traces and 34 000 earthquake locations on a shaded-relief map. The online database contains attributes for 123 faults mentioned in the literature, with Quaternary and geodetic slip rates reported for 38 and 26 faults respectively, and earthquake history reported for 39 faults. All data are accessible for viewing and download via http://www.geo.uni-tuebingen.de/faults/. This work has implications for seismic hazard studies in central Asia as it summarizes important fault parameters, and can reduce earthquake risk by enhancing public access to information. It also allows scientists and hazard assessment teams to identify structures and regions where data gaps exist and future investigations are needed.

  12. Quaternary glaciation of the Bale Mountains, Ethiopia

    NASA Astrophysics Data System (ADS)

    Osmaston, Henry A.; Mitchell, Wishart A.; Osmaston, J. A. Nigel

    2005-09-01

    Central Ethiopia comprises a high plateau at 2000-3000 m, formed from Tertiary lava flows and bisected by the Eastern African Rift. Ten volcanic mountains rise to altitudes of just over 4000 m, but on only three has Quaternary glaciation been substantiated by published field observations. On the Bale Mountains (4400 m), a previous report based on limited evidence proposed an ice-cap extending to 600 km2. Based on aerial photographs and ground surveys, this paper reports evidence of a more complex situation. A wide spread of large erratic boulders on the plateau records a central ice cap of 30 km2, though ice probably extended for a further 40 km2. Further north two groups of deeply incised and clearly glaciated valleys contain moraines and roches moutonnées (60 km2). On interfluves between them and on the open north slopes are moraines from an earlier stage of the same glaciation or from a distinct older event. Altogether about 180 km2 may have been glaciated. Cores dated by 14C from inside and outside the glaciated area suggest that at least the northern valley glaciers may date from the Last Glacial Maximum. Estimated equilibrium line altitudes for these glaciers and the ice-cap are 3750-4230 m. Copyright

  13. Luminescence dating of quaternary sediments: recent advances

    NASA Astrophysics Data System (ADS)

    Duller, G. A. T.

    2004-02-01

    Luminescence dating is unique amongst geochronological methods in dating the deposition of sediments based upon the properties of the constituent minerals. For Quaternary sediments the event being dated is the last exposure of the grains to daylight, and an implicit assumption is that this exposure was sufficient to remove any pre-existing signal. Until recently it has been difficult to test this assumption, other than by dating samples from a given depositional context with an age that is known from independent methods. There have been a series of technological and methodological developments in the past 5-10 yr that make it possible to undertake many replicate measurements of the luminescence from a single sample and hence to explicitly test whether for a specific sample all the grains had their luminescence signal reset at deposition. This allows the reliability of the luminescence age to be assessed. Where all the grains in a sample were not exposed to sufficient daylight to reset their luminescence signal, the apparent age will be an average value of the luminescence from all the grains measured at one time. Where many grains are measured simultaneously, this will overestimate the depositional age. The distribution of apparent age can be made clear by reducing the number of grains being measured in a given experiment, ultimately to the point of measuring individual sand-sized mineral grains. Copyright

  14. All-carbon graphene bioelectronics.

    PubMed

    Nam, Sungwoo; Chun, Sunggyu; Choi, Jonghyun

    2013-01-01

    We report nano field-effect transistor (nanoFET) biosensors built from the monolithic integration of graphene and graphite. The monolithic integration enables nanoscopic field-effect detection of chemical and biological signals with mechanically flexible and robust interface with biological systems in several respects. Our nanoFET biosensors exhibit superior detection sensitivity, mechanical flexibility and nanoscopic detection resolution. First, we demonstrate that electrical detection can be achieved from nanoscale electric field modulation of the graphene channel while the signal integrity is not perturbed by mechanical deflection of graphene nanoFET sensors. Such capability is introduced by the advanced design of monolithic graphene-graphite without any need for metal-graphene heterointerfaces. Second, we explore the chemical detection capability of graphene nanoFET sensors, and show that our sensors are responsive to localized chemical environmental changes/perturbations. Our nanoFET sensors not only show clear response to nanoscopic charge perturbation but also demonstrate potential 3-D sensing capability due to the advanced monolithic graphene-graphite mechanical design. These unique capabilities of our monolithic graphene-graphite bioelectronics could be exploited in chemical and biological detection and conformal interface with biological systems in the future.

  15. The isotope hydrology of Quaternary climate change.

    PubMed

    Darling, W G

    2011-04-01

    Understanding the links between climate change and human migration and culture is an important theme in Quaternary archaeology. While oxygen and hydrogen stable isotopes in high-latitude ice cores provide the ultimate detailed record of palaeoclimate extending back to the Middle Pleistocene, groundwater can act as a climate archive for areas at lower latitudes, permitting a degree of calibration for proxy records such as lake sediments, bones, and organic matter. Not only can oxygen and hydrogen stable isotopes be measured on waters, but the temperature of recharge can be calculated from the amount of the atmospheric noble gases neon, argon, krypton, and xenon in solution, while residence time can be estimated from the decay of the radioisotopes carbon-14, chlorine-36, and krypton-81 over timescales comparable to the ice core record. The Pleistocene-Holocene transition is well characterised in aquifers worldwide, and it is apparent that isotope-temperature relationships of the present day are not necessarily transferable to past climatic regimes, with important implications for the interpretation of proxy isotope data. Groundwaters dating back to one million years, i.e., to beyond the Middle Pleistocene, are only found in major aquifer basins and information is relatively sparse and of low resolution. Speleothem fluid inclusions offer a way of considerably increasing this resolution, but both speleothem formation and large-scale groundwater recharge requires humid conditions, which may be relatively infrequent for areas currently experiencing arid climates. Both types of record therefore require caution in their interpretation when considering a particular archaeological context.

  16. Landward-advancing Quaternary eolianites of Bermuda

    NASA Astrophysics Data System (ADS)

    Rowe, Mark P.; Bristow, Charlie S.

    2015-12-01

    The landscape of Bermuda is dominated by Quaternary carbonate cemented dunes, or "eolianites", which form the islands' topography. Sections through the dunes are revealed in extensive natural and man-made rock faces, which expose the dune stratigraphy as well as the preserved morphology. An analysis of 3751 foreset measurements confirms the conclusion reached by earlier researchers that Bermuda's dunes advanced sub-perpendicularly to the coast in a landward direction away from source beaches. Dune orientation, being multi-directional, is not consistent with northeast net sand transportation predicted by a drift potential analysis of modern wind data. The putative predisposition of Bermuda's carbonate dunes to rapid cementation is supposed to have curtailed their landward advance such that younger dunes developed as static ridges at the seaward margin of their lithified predecessors. Geological mapping has revealed, however, that in many cases young dunes did advance inland onto interior terrain, overstepping older dune ridges. Molds of large trees, preserved within the dunes, and a sharp contact of steep slip-face dune foresets on palaeosols evoke the encroachment of landward-advancing precipitation ridges into a forested landscape. The internal structure of the dunes, featuring thick sets of slip-face foresets truncated by sub-horizontal planar bounding surfaces, uphold the ascendancy of sand transportation processes over those of sand retention and vertical accretion. Although meteoric cementation was responsible for the ultimate preservation of eolianite ridges which dominate Bermuda's landscape, it took effect too slowly to influence the behaviour of the carbonate dunes at the time of their emplacement.

  17. Late Quaternary fire regimes of Australasia

    NASA Astrophysics Data System (ADS)

    Mooney, S. D.; Harrison, S. P.; Bartlein, P. J.; Daniau, A.-L.; Stevenson, J.; Brownlie, K. C.; Buckman, S.; Cupper, M.; Luly, J.; Black, M.; Colhoun, E.; D'Costa, D.; Dodson, J.; Haberle, S.; Hope, G. S.; Kershaw, P.; Kenyon, C.; McKenzie, M.; Williams, N.

    2011-01-01

    We have compiled 223 sedimentary charcoal records from Australasia in order to examine the temporal and spatial variability of fire regimes during the Late Quaternary. While some of these records cover more than a full glacial cycle, here we focus on the last 70,000 years when the number of individual records in the compilation allows more robust conclusions. On orbital time scales, fire in Australasia predominantly reflects climate, with colder periods characterized by less and warmer intervals by more biomass burning. The composite record for the region also shows considerable millennial-scale variability during the last glacial interval (73.5-14.7 ka). Within the limits of the dating uncertainties of individual records, the variability shown by the composite charcoal record is more similar to the form, number and timing of Dansgaard-Oeschger cycles as observed in Greenland ice cores than to the variability expressed in the Antarctic ice-core record. The composite charcoal record suggests increased biomass burning in the Australasian region during Greenland Interstadials and reduced burning during Greenland Stadials. Millennial-scale variability is characteristic of the composite record of the sub-tropical high pressure belt during the past 21 ka, but the tropics show a somewhat simpler pattern of variability with major peaks in biomass burning around 15 ka and 8 ka. There is no distinct change in fire regime corresponding to the arrival of humans in Australia at 50 ± 10 ka and no correlation between archaeological evidence of increased human activity during the past 40 ka and the history of biomass burning. However, changes in biomass burning in the last 200 years may have been exacerbated or influenced by humans.

  18. Seismic stratigraphy and depositional history of late Quaternary deposits in the Yellow Sea.

    NASA Astrophysics Data System (ADS)

    Lee, Gwang-Soo; Yoo, Dong Geun; Bae, Sungho; Choul Kim, Dae; Yi, Hi-Il

    2016-04-01

    To identify the seismic stratigraphy and depositional history of late Quaternary deposits in the Yellow Sea, approximately 52,600 line-km of Chirp seismic profiles and 5,060 line-km of Sparker seismic profiles were analyzed. The Yellow Sea are correspond to three sedimentary environments: (1) a various scale sand ridges/waves and mud belt (the western inner-shelf of the Korean Peninsula), (2) recent- and paleo-channels, erosional and broad surface (the center of the Yellow Sea), and (3) prodelta mud patch (the eastern offshore of China). Based on the seismic stratigraphic analysis of seismic profiles, the late Quaternary deposits in the Yellow Sea are divided into five distinctive seismic units (units CY1~5), consisting of two depositional sequences that can be defined as erosional and disconformable strata. Each unit show different seismic facies and geometry, and is clearly separated by each bounding surface. The major depositional processes and sediment dispersal systems during the late Quaternary in the Yellow Sea are: (1) regressive estuarine/deltaic deposits (unit CY1), (2) transgressive incised channel fill (unit CY2), (3) transgressive sand sheet (unit CY3), (4) transgressive sand ridges (unit CY4), and (5) prodelta/recent mud (unit CY5). The depositional sequences follow the general concepts of sequence stratigraphy very well. Lower sequence (DI) correspond to the falling stage systems tract regarded as regressive estuarine or deltaic deposits (unit CY1), whereas upper sequence (DII) consists of a set of the transgressive (units CY2, CY3, and CY4) and highstand systems tract (unit CY5) formed since the last-glacial period.

  19. Quaternary landscape evolution driven by slab-pull mechanisms in the Granada Basin (Central Betics)

    NASA Astrophysics Data System (ADS)

    Pérez-Peña, J. V.; Azañón, J. M.; Azor, A.; Booth-Rea, G.; Galve, J. P.; Roldán, F. J.; Mancilla, F.; Giaconia, F.; Morales, J.; Al-Awabdeh, M.

    2015-11-01

    The Granada Basin is one of the largest Neogene-Quaternary intramontane basins of the Betic Cordillera in SE Spain. The landscape evolution in this basin is complex and does not respond to a simple model of headward erosion following river capture of a former endorheic catchment. In the NE border of the basin, the drainage network is highly incised and reveals two different stages of river development since the Pleistocene. The older drainage network presents low incision, being locally controlled by ENE-WSW open folds. The present-day drainage network features deep incised valleys with a well-defined local base-level controlled by NW-SE normal faults. The ENE-WSW open folds were generated by compressional stresses and affect a geomorphic surface that caps the local sedimentary sequence. These folds are thought to reactivate a Pliocene roll-over formed in the hanging wall of ENE-WSW normal faults that bound the Granada Basin to the north and the deepest Pliocene depocenter. On the contrary, Quaternary depocenters are located in the hanging wall of the NW-SE-oriented normal faults that control the present-day drainage network (NW-SE oriented). The activity of these faults also contributes to the erosion of the Pliocene depocenter located to the north, thus suggesting a southwestward migration of the loci of extension to the center of the basin. The broad-scale scenario envisaged to explain the Pliocene-Quaternary evolution of the NE border of the Granada Basin is one dominated by mantle slab-pull coeval with the Africa-Iberia continuous convergence.

  20. Tertiary and Quaternary Research with Remote Sensing Methods

    NASA Technical Reports Server (NTRS)

    Conel, J. E.

    1985-01-01

    Problems encountered in mapping the Quaternary section of the Wind River Region using remote sensing methods are discussed. Analysis of the stratigraphic section is a fundamental aspect of the geologic study of sedimentary basins. Stratigraphic analysis of post-Cretaceous rocks in the Wind River Basin encounters problems of a distinctly different character from those involved in studying the pre-Cretaceous section. The interior of the basin is predominantly covered by Tertiary and Quaternary sediments. These rocks, except on the basin margin to the north, are mostly flat lying or gently dipping. The Tertiary section consists of sandstones, siltstones, and tuffaceous sediments, some variegated, but in general poorly bedded and of great lithologic similarity. The Quaternary sediments consist of terrace, fan, and debris tongue deposits, unconsolidated alluvium occupying the bottoms of modern watercourses, deposits of eolian origin and tufa. Terrace and fan deposits are compositionally diverse and reflect the lithologic diversity of the source terranes.

  1. [The biological activity of quaternary ammonium salts (QASs)].

    PubMed

    Obłak, Ewa; Gamian, Andrzej

    2010-01-01

    Quaternary ammonium salts (QASs), especially those of cationic surfactant character, are applied as antibacterial and antifungal disinfectants. QASs affect lipid-enveloped viruses, including human immunodeficiency virus (HIV) and hepatitis B virus (HBV), but not non-enveloped viruses. These compounds are extensively used in domestic (as ingredients of shampoos, hair conditioners), agricultural (as fungicides, pesticides, insecticides), healthcare (as medications), and industrial applications (as biocides, fabric softeners, corrosion inhibitors). The extensive use of quaternary ammonium disinfectants in recent years has led to the development of resistance in microorganisms to these drugs. Thus Staphylococcus aureus strains contain the plasmid-carrying genes qacA and qacB encoding resistance to quaternary ammonium compounds and acriflavine. The membrane proteins QacA and QacB confer multidrug resistance by exporting the compound by the proton motive force which is generated by the transmembrane electrochemical proton gradient. PMID:20400784

  2. Quaternary naltrexone reverses radiogenic and morphine-induced locomotor hyperactivity

    SciTech Connect

    Mickley, G.A.; Stevens, K.E.; Galbraith, J.A.; White, G.A.; Gibbs, G.L.

    1984-04-01

    The present study attempted to determine the relative role of the peripheral and central nervous system in the production of morphine-induced or radiation-induced locomotor hyperactivity of the mouse. Toward this end, we used a quaternary derivative of an opiate antagonist (naltrexone methobromide), which presumably does not cross the blood-brain barrier. Quaternary naltrexone was used to challenge the stereotypic locomotor response observed in these mice after either an i.p. injection of morphine or exposure to 1500 rads /sup 60/Co. The quaternary derivative of naltrexone reversed the locomotor hyperactivity normally observed in the C57BL/6J mouse after an injection of morphine. It also significantly attenuated radiation-induced locomotion. The data reported here support the hypothesis of endorphin involvement in radiation-induced and radiogenic behaviors. However, these conclusions are contingent upon further research which more fully evaluates naltrexone methobromide's capacity to cross the blood-brain barrier.

  3. Atmospheric effects on Quaternary polarization encoding for free space communication

    NASA Astrophysics Data System (ADS)

    Soorat, Ram; Vudayagiri, Ashok

    2016-10-01

    We have simulated atmospheric effects such as fog and smoke in laboratory environment to simulate depolarisation due to atmospheric effects during a free space optical communi- cation. This has been used to study noise in two components of quaternary encoding for polarization shift keying. Individual components of a Quaternary encoding, such as vertical and horizontal as well as 45$^\\circ$ and 135$^\\circ$ , are tested separately and indicates that the depo- larization effects are different for these two situation. However, due to a differential method used to extract information bits, the protocol shows extremely low bit error rates. The information obtained is useful during deployment of a fully functional Quaternary encoded PolSK scheme in free space.

  4. Characterization of Quaternary and suspected Quaternary faults, Amargosa area, Nevada and California

    SciTech Connect

    Anderson, R.E.; Crone, A.J.; Machette, M.N.; Bradley, L.A.; Diehl, S.F.

    1995-12-31

    This report presents the results of geologic studies that help define the Quaternary history of selected faults in the region around Yucca Mountain, Nevada. These results are relevant to the seismic-design basis of a potential nuclear waste repository at Yucca Mountain. The relevancy is based, in part, on a need for additional geologic data that became apparent in ongoing studies by S. Pezzopane (written commun., 1995) that resulted in the identification of 51 relevant and potentially relevant (see appendix A for definitions) individual and compound faults and fault zones in the 100-km-radius region around the Yucca Mountain site. These structures were divided into local and regional categories by Pezzopane (1995); this report deals with selected regional structures. In this introduction, the authors outline the scope and strategy of the studies and the tectonic environment of the studied structures.

  5. Ice Age Earth: Late Quaternary geology and climate

    SciTech Connect

    Dawson, A.G.

    1992-01-01

    This book is a concise and readable account of the most important geologic records of the late Quaternary. It provides a synopsis of the major environmental changes that took place from approximately 13,000 to 7,000 years ago, highlighting the complexity and rapidity of past climate changes and the environmental responses they produced. The text is well illustrated, though some figures are rough and need more explanation. Also needed is a critical appraisal of the geochronology which places the paleoenvironmental records into the temporal domain. However, as a whole the book reaches its objective of summarizing the most important scientific findings about the nature of the late Quaternary climate changes.

  6. Petrology and Geochemistry of Quaternary Mafic Volcanism in the Northern of Lake Van, Eastern Anatolia Collision Zone, Turkey

    NASA Astrophysics Data System (ADS)

    Oyan, Vural; Keskin, Mehmet; Ünal, Esin; Sharkov, Evgenii V.

    2013-04-01

    Quaternary mafic lavas in the north of Lake Van erupted not only from eruption center like Girekol miniature shield volcano but also from N-S (Yüksektepe volcanic field) and E-W (Ormuktepe volcanic field) extending extensional fractures. Literature K/Ar dates (Lebedev et al., 2010) indicate that the basaltic and hawaiitic lavas erupted in a period between 1.08 and 0.36 Ma. These lavas are composed of olivine, plagioclase, augite and titanoaugite crystals and display porphyritic to aphyric textures. Major oxide, trace element and isotopic characteristics of the Quaternary lavas indicate that hawaiitic lavas are the fractionated derivates of a primitive alkali basaltic magma via fractional crystallization combined with assimilation process. Results of our AFC and EC-AFC models imply that alkali basaltic lavas assimilated negligible crustal material (~2%) in contrast to the hawaiitic lavas that experienced crustal contamination between 3% and 10%. LIL and LRE elements of the most primitive lavas display enrichments relative to HFS elements on N- MORB-normalized spidergrams while their lead isotopic ratios exhibit trends heading towards the EM2 type mantle, implying the importance of a distinct subduction component in the source. To evaluate partial melting processes in mantle source region of the Quaternary mafic volcanism, we conducted partial melting models. Results of our models suggest the presence of both garnet and spinel peridotite as the sources material with a partial melting degree ~5 % and mixing of the derivative melts from them in the genesis of the mafic alkaline lavas.

  7. 40 CFR 721.9075 - Quaternary ammonium salt of fluorinated alkylaryl amide.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Quaternary ammonium salt of... New Uses for Specific Chemical Substances § 721.9075 Quaternary ammonium salt of fluorinated alkylaryl... identified generically as quaternary ammonium salt of fluorinated alkylaryl amide (PMN No. P-92-688)...

  8. 40 CFR 721.9075 - Quaternary ammonium salt of fluorinated alkylaryl amide.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Quaternary ammonium salt of... New Uses for Specific Chemical Substances § 721.9075 Quaternary ammonium salt of fluorinated alkylaryl... identified generically as quaternary ammonium salt of fluorinated alkylaryl amide (PMN No. P-92-688)...

  9. 40 CFR 721.9075 - Quaternary ammonium salt of fluorinated alkylaryl amide.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Quaternary ammonium salt of... New Uses for Specific Chemical Substances § 721.9075 Quaternary ammonium salt of fluorinated alkylaryl... identified generically as quaternary ammonium salt of fluorinated alkylaryl amide (PMN No. P-92-688)...

  10. 40 CFR 721.9075 - Quaternary ammonium salt of fluorinated alkylaryl amide.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Quaternary ammonium salt of... New Uses for Specific Chemical Substances § 721.9075 Quaternary ammonium salt of fluorinated alkylaryl... identified generically as quaternary ammonium salt of fluorinated alkylaryl amide (PMN No. P-92-688)...

  11. 40 CFR 721.9075 - Quaternary ammonium salt of fluorinated alkylaryl amide.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Quaternary ammonium salt of... New Uses for Specific Chemical Substances § 721.9075 Quaternary ammonium salt of fluorinated alkylaryl... identified generically as quaternary ammonium salt of fluorinated alkylaryl amide (PMN No. P-92-688)...

  12. Quaternary Ammonium Disinfectant Issues Encountered in an Environmental Services Department.

    PubMed

    Boyce, John M; Sullivan, Linda; Booker, Arica; Baker, James

    2016-03-01

    We identified several factors affecting the use of quaternary ammonium-based (Quat) disinfectant in our facility. Microfiber wipers, cotton towels, and 1 of 2 types of disposable wipes soaked in a Quat disinfectant revealed significant binding of the disinfectant. Concentrations of Quat delivered by automated disinfectant dispensers varied widely.

  13. Quaternary Glacial Mapping in Western Wisconsin Using Soil Survey Information

    ERIC Educational Resources Information Center

    Oehlke, Betsy M.; Dolliver, Holly A. S.

    2011-01-01

    The majority of soils in the western Wisconsin have developed from glacial sediments deposited during the Quaternary Period (2.6 million years before present). In many regions, multiple advances and retreats have left a complex landscape of diverse glacial sediments and landforms. The soils that have developed on these deposits reflect the nature…

  14. 21 CFR 172.165 - Quaternary ammonium chloride combination.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Quaternary ammonium chloride combination. 172.165 Section 172.165 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Food...

  15. Application of Analytic Geometry to Ternary and Quaternary Diagrams.

    ERIC Educational Resources Information Center

    MacCarthy, Patrick

    1986-01-01

    Advantages of representing ternary and quaternary composition diagrams by means of rectangular coordinates were pointed out in a previous paper (EJ 288 693). A further advantage of that approach is that analytic geometry, based on rectangular coordinates, is directly applicable as demonstrated by the examples presented. (JN)

  16. Response to comment on "No late Quaternary strike-slip motion along the northern Karakoram fault"

    NASA Astrophysics Data System (ADS)

    Robinson, Alexander C.; Owen, Lewis A.; Chen, Jie; Schoenbohm, Lindsay M.; Hedrick, Kathryn A.; Blisniuk, Kimberly; Sharp, Warren D.; Imrecke, Daniel B.; Li, Wenqiao; Yuan, Zhaode; Caffee, Marc W.; Mertz-Kraus, Regina

    2016-06-01

    In their comment on "No late Quaternary strike-slip motion along the northern Karakoram fault", while Chevalier et al. (2016) do not dispute any of the results or interpretations regarding our observations along the main strand of the northern Karakoram fault, they make several arguments as to why they interpret the Kongur Shan Extensional System (KES) to be kinematically linked to the Karakoram fault. These arguments center around how an "active" fault is defined, how slip on segments of the KES may be compatible with dextral shear related to continuation of the Karakoram fault, and suggestions as to how the two fault systems might still be connected. While we appreciate that there are still uncertainties in the regional geology, we address these comments and show that their arguments are inconsistent with all available data, known geologic relationships, and basic kinematics.

  17. Genetic footprints of demographic expansion in North America, but not Amazonia, during the Late Quaternary

    PubMed Central

    Lessa, Enrique P.; Cook, Joseph A.; Patton, James L.

    2003-01-01

    The biotic consequences of climate change have attracted considerable attention. In particular, the “refugial debate” centers on the possible retraction of habitats to limited areas that may have served as refuges for many associated species, especially during glaciations of the Quaternary. One prediction of such scenarios is that populations must have experienced substantial growth accompanying climatic amelioration and the occupation of newly expanded habitats. We used coalescence theory to examine the genetic evidence, or lack thereof, for late Pleistocene refugia of boreal North American and tropical Amazonian mammals. We found substantial and concordant evidence of demographic expansion in North American mammals, particularly at higher latitudes. In contrast, small mammals from western Amazonia appear to have experienced limited or no demographic expansion after the Late Pleistocene. Thus, demographic responses to climate change can be tracked genetically and appear to vary substantially across the latitudinal gradient of biotic diversity. PMID:12913123

  18. Late-Quaternary climatic change on the American North Pacific Coast

    NASA Technical Reports Server (NTRS)

    Heusser, C. J.; Heusser, L. E.; Peteet, D. M.

    1985-01-01

    The late Quaternary climate of the North Pacific, where according to modelling the solar radiation in the early Holocene at the time of the summer solstice is high and in the late Holocene is relatively low, is investigated. Quantitative temperature and precipitation estimates from southern Alaska are compared with estimates from western Washington and British Columbia. Data extending over more than 10,000 years show a broadly consistent pattern of climatic change in general agreement with predicted variations in solar radiation and their effect on atmospheric circulation and seasonal duration of pressure systems over the North Pacific Ocean. In the early Holocene, the subtropical North Pacific anticyclone annually regulated climate for a longer period at higher latitudes than at present, so that warmth and dryness increased in southern Alaska. The Aleutian low-pressure center intensified during the late Holocene, resulting in colder and more humid coastal climate and increased frequency of glacier growth in the cordillera.

  19. Alkaline Basalts of The Quaternary Buffalo Valley Volcanic Field, NW Fish Creek Mountains, North-central Nevada, Great Basin

    NASA Astrophysics Data System (ADS)

    Cousens, B.; Henry, C. D.

    2008-12-01

    The Buffalo Valley volcanic field, 5 km southwest of Battle Mountain, consists of approximately 11 cinder cones and associated flows. Youthful volcanoes are rare in the region, and thus this field offers the opportunity to investigate mantle sources currently beneath the central Great Basin. Most of the eruptive centers are distributed along the northwestern margin of the Fish Creek Mountains, a mid-Tertiary caldera complex, along a 13-km-long northeasterly trend that is perpendicular to the regional stress field (or GPS velocity field), suggesting fault control or eruption from a now-buried fissure. The cones are geomorphologically youthful, with well-defined, commonly breached craters. At least one cone, situated slightly east of the main trend, consists of only a thin mantle of scoria and bombs overlying grey Paleozoic limestone. Previous K-Ar and Ar-Ar dating indicate that the cones are between 1.29 and 0.95 Ma in age. Two other nearby Quaternary volcanic centers lie northeast of the Fish Creek Mountains (K-Ar date of 3.3 Ma) and in the center of the Fish Creek caldera (age unknown). Rare Tertiary basalts and more common Tertiary andesites lie around the margin of the caldera. Lavas from the Buffalo Valley cones have vesicular flow tops and more massive interiors. All Quaternary centers are similar petrographically, including 1-2% olivine phenocrysts and megacrysts up to 1 cm in size, and characteristic plagioclase megacrysts that are rarely up to 4 cm long, commonly in a glassy matrix. Two cone samples are alkalic basalt and tephrite with Mg numbers of 0.55, high TiO2 (2.4%), K2O (2.0%), light REE, Nb (60 ppm), but low Cr and Ni (80 ppm), Pb (2 ppm), Ba (450 ppm) and 87Sr/86Sr (0.70375) compared to Late Pliocene/Quaternary volcanic rocks from the western Great Basin near Reno/Carson City/Fallon. The Buffalo Valley cones are similar chemically to lavas from the Pliocene-Quaternary Lunar Craters volcanic field in central Nevada, and are melts of mantle that is

  20. Quinine-derived thiourea and squaramide catalyzed conjugate addition of α-nitrophosphonates to enones: asymmetric synthesis of quaternary α-aminophosphonates.

    PubMed

    Bera, Kalisankar; Namboothiri, Irishi N N

    2015-02-01

    Conjugate addition of α-nitrophosphonates to enones was carried out in the presence of two sets of organocatalysts, viz. a quinine-thiourea and a quinine-squaramide. The quinine-thiourea provided the products possessing an α-quaternary chiral center in high enantioselectivities only in the case of electron rich enones. On the other hand, the quinine-squaramide was more efficient in that a wide variety of electron rich and electron poor enones underwent Michael addition of nitrophosphonates to afford the quaternary α-nitrophosphonates in excellent yields and enantioselectivities. The hydrogen bonding donor ability of the bifunctional catalyst, as shown in the proposed transition states, appears primarily responsible for the observed selectivity. However, a favorable π-stacking between the aryl groups of thiourea/squaramide and aryl vinyl ketone also appeared favorable. The reaction was amenable to scale up, and the enantioenriched quaternary α-nitrophosphonates could be easily transformed to synthetically and biologically useful quaternary α-aminophosphonates and other multifunctional molecules.

  1. Characterization of Quaternary and suspected Quaternary faults, regional studies, Nevada and California

    SciTech Connect

    Anderson, R.E.; Bucknam, R.C.; Crone, A.J.; Haller, K.M.; Machette, M.N.; Personius, S.F.; Barnhard, T.P.; Cecil, M.J.; Dart, R.L.

    1995-12-31

    This report presents the results of geologic studies that help define the Quaternary history of selected faults in the region around Yucca Mountain, Nevada. These results are relevant to the seismic-design basis of a potential nuclear waste repository at Yucca Mountain. The relevancy is based, in part, on a need for additional geologic data that became apparent in ongoing studies that resulted in the identification of 51 relevant and potentially relevant individual and compound faults and fault zones in the 100-km-radius region around the Yucca Mountain site. Geologic data used to characterize the regional faults and fault zones as relevant or potentially relevant seismic sources includes age and displacement information, maximum fault lengths, and minimum distances between the fault and the Yucca Mountain site. For many of the regional faults, no paleoseismic field studies have previously been conducted, and age and displacement data are sparse to nonexistent. In November 1994, the Branch of Earthquake and Landslide Hazards entered into two Memoranda of Agreement with the Yucca Mountain Project Branch to conduct field reconnaissance, analysis, and interpretation of six relevant and six potentially relevant regional faults. This report describes the results of study of those faults exclusive of those in the Pahrump-Stewart Valley-Ash Meadows-Amargosa Valley areas. We also include results of a cursory study of faults on the west flank of the Specter Range and in the northern part of the Last Chance Range. A four-phase strategy was implemented for the field study.

  2. Comparative analyses of quaternary arrangements in homo-oligomeric proteins in superfamilies: Functional implications.

    PubMed

    Sudha, Govindarajan; Srinivasan, Narayanaswamy

    2016-09-01

    A comprehensive analysis of the quaternary features of distantly related homo-oligomeric proteins is the focus of the current study. This study has been performed at the levels of quaternary state, symmetry, and quaternary structure. Quaternary state and quaternary structure refers to the number of subunits and spatial arrangements of subunits, respectively. Using a large dataset of available 3D structures of biologically relevant assemblies, we show that only 53% of the distantly related homo-oligomeric proteins have the same quaternary state. Considering these homologous homo-oligomers with the same quaternary state, conservation of quaternary structures is observed only in 38% of the pairs. In 36% of the pairs of distantly related homo-oligomers with different quaternary states the larger assembly in a pair shows high structural similarity with the entire quaternary structure of the related protein with lower quaternary state and it is referred as "Russian doll effect." The differences in quaternary state and structure have been suggested to contribute to the functional diversity. Detailed investigations show that even though the gross functions of many distantly related homo-oligomers are the same, finer level differences in molecular functions are manifested by differences in quaternary states and structures. Comparison of structures of biological assemblies in distantly and closely related homo-oligomeric proteins throughout the study differentiates the effects of sequence divergence on the quaternary structures and function. Knowledge inferred from this study can provide insights for improved protein structure classification and function prediction of homo-oligomers. Proteins 2016; 84:1190-1202. © 2016 Wiley Periodicals, Inc.

  3. Electrostatic Layer-By-Layer Self-Assembled Graphene/Multi-Walled Carbon Nanotubes Hybrid Multilayers as Efficient 'All Carbon' Supercapacitors.

    PubMed

    Gupta, Sanju; Heintzman, Eli; Price, Carson

    2016-05-01

    In this work, covalently bonded graphene/carbon nanotube (Gr/CNT) conjoined materials are fabricated as engineered three-dimensional hybrid multilayer supercapacitors for high-performance integrated electrochemical energy storage. Stable aqueous dispersion of polymer-modified graphene sheets are prepared in the presence of cationic poly(ethyleneimine), PEI (PEI-Gr) for sequential or electrostatic layer-by-layer (E-LBL) self-assembly with negatively charged acid-oxidized or functionalized multi-walled CNT (fMWCNT), forming (PEI-Gr/fMWCNT)n architecture as "all carbon" super-capacitor, where n = 1, 2, 4, 6, 9, 12 and 15. These films possess an interconnected network of mesoporous nanocarbon structure with well-defined interfaces allowing sufficient surface adsorption and faster ion transport due to short diffusion distances. They exhibit nearly rectangular cyclic voltammograms at an exceedingly high scan rate of 1 V/s with an average specific capacitance of -450 F g(-1) and specific energy density of 75.5 Wh kg(-1) based on electrode weight, measured at a current density of 0.3 A g(-1), comparable to that of Ni metal hydride battery and charged/discharged within a few seconds or a minute. This is attributed to the maximized synergistic effect of the highest specific surface areas by preventing re-aggregation of PEI-Gr or PEI-rGO via fMWCNT as spacers. We also determined relative contributions of the interfacial capacitance (C(dl)) and charge transfer (R(ct)) properties of the hybrids and investigated interfacial properties by SECM technique. PMID:27483821

  4. Electrostatic Layer-By-Layer Self-Assembled Graphene/Multi-Walled Carbon Nanotubes Hybrid Multilayers as Efficient 'All Carbon' Supercapacitors.

    PubMed

    Gupta, Sanju; Heintzman, Eli; Price, Carson

    2016-05-01

    In this work, covalently bonded graphene/carbon nanotube (Gr/CNT) conjoined materials are fabricated as engineered three-dimensional hybrid multilayer supercapacitors for high-performance integrated electrochemical energy storage. Stable aqueous dispersion of polymer-modified graphene sheets are prepared in the presence of cationic poly(ethyleneimine), PEI (PEI-Gr) for sequential or electrostatic layer-by-layer (E-LBL) self-assembly with negatively charged acid-oxidized or functionalized multi-walled CNT (fMWCNT), forming (PEI-Gr/fMWCNT)n architecture as "all carbon" super-capacitor, where n = 1, 2, 4, 6, 9, 12 and 15. These films possess an interconnected network of mesoporous nanocarbon structure with well-defined interfaces allowing sufficient surface adsorption and faster ion transport due to short diffusion distances. They exhibit nearly rectangular cyclic voltammograms at an exceedingly high scan rate of 1 V/s with an average specific capacitance of -450 F g(-1) and specific energy density of 75.5 Wh kg(-1) based on electrode weight, measured at a current density of 0.3 A g(-1), comparable to that of Ni metal hydride battery and charged/discharged within a few seconds or a minute. This is attributed to the maximized synergistic effect of the highest specific surface areas by preventing re-aggregation of PEI-Gr or PEI-rGO via fMWCNT as spacers. We also determined relative contributions of the interfacial capacitance (C(dl)) and charge transfer (R(ct)) properties of the hybrids and investigated interfacial properties by SECM technique.

  5. Building Congested Ketone: Substituted Hantzsch Ester and Nitrile as Alkylation Reagents in Photoredox Catalysis.

    PubMed

    Chen, Wenxin; Liu, Zheng; Tian, Jiaqi; Li, Jin; Ma, Jing; Cheng, Xu; Li, Guigen

    2016-09-28

    For the first time, 4-alkyl Hantzsch esters were used to construct molecules with all-carbon quaternary centers by visible light-induced photoredox catalysis via transfer alkylation. Up to a 1500 h(-1) turnover frequency was achieved in this reaction. Reactions of 4-alkyl Hantzsch nitriles as tertiary radical donors joined two contiguous all-carbon quaternary centers intermolecularly, and this chemistry was used to synthesize a common precursor of a class of hydroxysteroid dehydrogenase inhibitors. PMID:27622653

  6. Mapping a buried Quaternary valley and pre-Quaternary faults through seismic methods in Copenhagen, Denmark.

    NASA Astrophysics Data System (ADS)

    Martinez, Kerim; Alfredo Mendoza, Jose; Henrik, Olsen

    2010-05-01

    Limited knowledge of the subsurface geology motivates the use of geophysical techniques before large engineering projects are conducted. These applications are normally restricted to satisfy the project aims, like mapping the near surface sediments, unconsolidated rocks and/or geological structures that may affect the construction locally. However, the applications can also contribute to the general knowledge of the regional geology around the location of interest. This report highlights the mapping of a buried Quaternary valley and identification of regional faults by a reflection and refraction seismic survey performed in Copenhagen. A 13.9 Km seismic survey was carried out at Copenhagen city along six crooked lines in order to determine the velocity fields in the near subsurface segment of a planned metro line and reflection patterns in deeper levels. The aim of the survey was to collect information needed for designing the underground metro. In particular it was sought to map the interface between Quaternary sedimentary layers of clay, till and sand, and the underlying layers of Palaeogene limestone found between 7 and 40 m below the ground surface. The data acquisition was carried out using a 192 channels array, receiver groups with 5 m spacing and a Vibroseis as a source at 5 m spacing following a roll along technique to complete the survey spreads. The urban environment demanded extensive survey planning including traffic control, notifications to residents and a fluent coordination with municipal authorities in order to minimize disturbances and ensure data acquisition. The reflection data was processed under a conventional scheme and the refraction data was interpreted using a non-linear traveltime tomography algorithm. The reflection results indicate the presence of faults oriented NW-SE to NNW-SSE affecting the limestone sequences. The faults may be associated to the Sorgenfrei-Tornquist Zone at the transition between the Danish Basin and the Baltic

  7. Active tectonics of the Oran (Algeria) Quaternary plain

    NASA Astrophysics Data System (ADS)

    youcef, Bouhadad; rabah, Bensalem; e-hadi, oubaiche

    2016-04-01

    The Oran region, in north-western Algeria, has been hit several times in the past by destructive moderate-sized and strong earthquakes. The Oran October 9th , 1790 (I0= X) was among the strongest seismic events in the western Mediterranean area comparable, if we consider the described effects, to the El- Asnam (1980, Ms=7.3) and Zemmouri (2003, Mw=6.8) earthquakes. Such strong seismic events requires the presence of major active geological structures that are re-activated several times in the past. In this work we present results of a multi- disciplinary study combining geomorphic analysis, field earthquake geological investigations and geophysical methods, undertaken to study the southern border of the Oran Quaternary plain. A 50 km long, SW-dipping and NE-SW trending active fault has been identified that showing clear quaternary deformation. Keywords: earthquake geology, active fault, geomorphic, geophysics, Algeria.

  8. Community ecology in a changing environment: Perspectives from the Quaternary

    PubMed Central

    Jackson, Stephen T.; Blois, Jessica L.

    2015-01-01

    Community ecology and paleoecology are both concerned with the composition and structure of biotic assemblages but are largely disconnected. Community ecology focuses on existing species assemblages and recently has begun to integrate history (phylogeny and continental or intercontinental dispersal) to constrain community processes. This division has left a “missing middle”: Ecological and environmental processes occurring on timescales from decades to millennia are not yet fully incorporated into community ecology. Quaternary paleoecology has a wealth of data documenting ecological dynamics at these timescales, and both fields can benefit from greater interaction and articulation. We discuss ecological insights revealed by Quaternary terrestrial records, suggest foundations for bridging between the disciplines, and identify topics where the disciplines can engage to mutual benefit. PMID:25901314

  9. New quantum codes constructed from quaternary BCH codes

    NASA Astrophysics Data System (ADS)

    Xu, Gen; Li, Ruihu; Guo, Luobin; Ma, Yuena

    2016-10-01

    In this paper, we firstly study construction of new quantum error-correcting codes (QECCs) from three classes of quaternary imprimitive BCH codes. As a result, the improved maximal designed distance of these narrow-sense imprimitive Hermitian dual-containing quaternary BCH codes are determined to be much larger than the result given according to Aly et al. (IEEE Trans Inf Theory 53:1183-1188, 2007) for each different code length. Thus, families of new QECCs are newly obtained, and the constructed QECCs have larger distance than those in the previous literature. Secondly, we apply a combinatorial construction to the imprimitive BCH codes with their corresponding primitive counterpart and construct many new linear quantum codes with good parameters, some of which have parameters exceeding the finite Gilbert-Varshamov bound for linear quantum codes.

  10. Community ecology in a changing environment: Perspectives from the Quaternary

    NASA Astrophysics Data System (ADS)

    Jackson, Stephen T.; Blois, Jessica L.

    2015-04-01

    Community ecology and paleoecology are both concerned with the composition and structure of biotic assemblages but are largely disconnected. Community ecology focuses on existing species assemblages and recently has begun to integrate history (phylogeny and continental or intercontinental dispersal) to constrain community processes. This division has left a "missing middle": Ecological and environmental processes occurring on timescales from decades to millennia are not yet fully incorporated into community ecology. Quaternary paleoecology has a wealth of data documenting ecological dynamics at these timescales, and both fields can benefit from greater interaction and articulation. We discuss ecological insights revealed by Quaternary terrestrial records, suggest foundations for bridging between the disciplines, and identify topics where the disciplines can engage to mutual benefit.

  11. Achieving optimum loop shapes in quaternary Pr-Co alloys

    NASA Astrophysics Data System (ADS)

    Branagan, D. J.; Kramer, M. J.; Tang, Yali; McCallum, R. W.

    2000-05-01

    The magnetic properties and microstructures of a quaternary Pr-Co-Ti-C alloy were investigated. After heat treating at 800 °C, the quaternary alloy developed high coercivity (16.7 kOe) and high energy product (8.6 MGOe). Hysteretic loop shapes exhibiting single-phase magnetic character were achieved which was a problem which previously plagued development of Pr-Co alloys. The optimum microstructure contained 75-100 nm Pr1Co5 hard magnetic grains, 75-100 nm Pr1Co2 second phases, and <10 nm TiC grain boundary precipitates. The important factors in achieving optimum loop shapes in Pr-Co alloys were examined in detail.

  12. Community ecology in a changing environment: Perspectives from the Quaternary

    USGS Publications Warehouse

    Jackson, Stephen T.; Blois, Jessica L.

    2015-01-01

    Community ecology and paleoecology are both concerned with the composition and structure of biotic assemblages but are largely disconnected. Community ecology focuses on existing species assemblages and recently has begun to integrate history (phylogeny and continental or intercontinental dispersal) to constrain community processes. This division has left a “missing middle”: Ecological and environmental processes occurring on timescales from decades to millennia are not yet fully incorporated into community ecology. Quaternary paleoecology has a wealth of data documenting ecological dynamics at these timescales, and both fields can benefit from greater interaction and articulation. We discuss ecological insights revealed by Quaternary terrestrial records, suggest foundations for bridging between the disciplines, and identify topics where the disciplines can engage to mutual benefit.

  13. New quantum codes constructed from quaternary BCH codes

    NASA Astrophysics Data System (ADS)

    Xu, Gen; Li, Ruihu; Guo, Luobin; Ma, Yuena

    2016-07-01

    In this paper, we firstly study construction of new quantum error-correcting codes (QECCs) from three classes of quaternary imprimitive BCH codes. As a result, the improved maximal designed distance of these narrow-sense imprimitive Hermitian dual-containing quaternary BCH codes are determined to be much larger than the result given according to Aly et al. (IEEE Trans Inf Theory 53:1183-1188, 2007) for each different code length. Thus, families of new QECCs are newly obtained, and the constructed QECCs have larger distance than those in the previous literature. Secondly, we apply a combinatorial construction to the imprimitive BCH codes with their corresponding primitive counterpart and construct many new linear quantum codes with good parameters, some of which have parameters exceeding the finite Gilbert-Varshamov bound for linear quantum codes.

  14. Helix Bundle Quaternary Structure from [alpha]/[beta]-Peptide Foldamers

    SciTech Connect

    Horne, W. Seth; Price, Joshua L.; Keck, James L.; Gellman, Samuel H.

    2008-11-18

    The function of a protein generally depends on adoption of a specific folding pattern, which in turn is determined by the side chain sequence along the polypeptide backbone. Here we show that the sequence-encoded structural information in peptides derived from yeast transcriptional activator GCN4 can be used to prepare hybrid {alpha}/{beta}-peptide foldamers that adopt helix bundle quaternary structures. Crystal structures of two hybrid {alpha}/{beta}-peptides are reported along with detailed structural comparison to {alpha}-peptides of analogous side chain sequence. There is considerable homology between {alpha}- and {alpha}/{beta}-peptides at the level of helical secondary structure, with modest but significant differences in the association geometry of helices in the quaternary structure.

  15. Luminescence dating of quaternary deposits in geology in Brazil.

    PubMed

    Tatumi, Sonia Hatsue; Gozzi, Giuliano; Yee, Márcio; de Oliveira, Victor Inácio; Sallun, Alethéa Ernandes Martins; Suguio, Kenitiro

    2006-01-01

    In the present work, systematic dating by luminescence methods has been done on 50 Quaternary geological samples within the study area of São Paulo State, Brazil. Bleaching experiments showed that residual TL intensity of 375 degrees C peak, of the quartz, was obtained after 10 h of sunlight exposition. Intensities decays of the 325 and 375 degrees C TL peaks can be fitted using second order exponential equation. Paleodose values were evaluated using regeneration methods with multiple aliquots. Samples dated indicate preliminary ages varying from 9 +/- 1 to 935 +/- 130 ka for colluvio-elluvial deposits, and from 17 +/- 2 to 215 +/- 30 ka for alluvial deposits of the study area. They cover four peneplained surfaces shaped during the Quaternary: I (1000-400 ka), II (400-120 ka), III (120-10 ka) and IV (10 ka until today), in decreasing order.

  16. Contrasting H-mode behaviour with deuterium fuelling and nitrogen seeding in the all-carbon and metallic versions of JET

    NASA Astrophysics Data System (ADS)

    Maddison, G. P.; Giroud, C.; Alper, B.; Arnoux, G.; Balboa, I.; Beurskens, M. N. A.; Boboc, A.; Brezinsek, S.; Brix, M.; Clever, M.; Coelho, R.; Coenen, J. W.; Coffey, I.; da Silva Aresta Belo, P. C.; Devaux, S.; Devynck, P.; Eich, T.; Felton, R. C.; Flanagan, J.; Frassinetti, L.; Garzotti, L.; Groth, M.; Jachmich, S.; Järvinen, A.; Joffrin, E.; Kempenaars, M. A. H.; Kruezi, U.; Lawson, K. D.; Lehnen, M.; Leyland, M. J.; Liu, Y.; Lomas, P. J.; Lowry, C. G.; Marsen, S.; Matthews, G. F.; McCormick, G. K.; Meigs, A. G.; Morris, A. W.; Neu, R.; Nunes, I. M.; Oberkofler, M.; Rimini, F. G.; Saarelma, S.; Sieglin, B.; Sips, A. C. C.; Sirinelli, A.; Stamp, M. F.; van Rooij, G. J.; Ward, D. J.; Wischmeier, M.; EFDA Contributors, JET

    2014-07-01

    The former all-carbon wall on JET has been replaced with beryllium in the main torus and tungsten in the divertor to mimic the surface materials envisaged for ITER. Comparisons are presented between type I H-mode characteristics in each design by examining respective scans over deuterium fuelling and impurity seeding, required to ameliorate exhaust loads both in JET at full capability and in ITER. Attention is focused upon a common high-triangularity, single-null divertor configuration at 2.5 MA, q95 ≈ 3.5 yielding the most robust all-C performance. Contrasting results between the alternative linings are found firstly in unseeded plasmas, for which purity is improved and intrinsic radiation reduced in the ITER-like wall (ILW) but normalized energy confinement is ≈30% lower than in all-C counterparts, owing to a commensurately lower (electron) pedestal temperature. Divertor recycling is also radically altered, with slower, inboard-outboard asymmetric transients at ELMs and spontaneous oscillations in between them. Secondly, nitrogen seeding elicits opposite responses in the ILW to all-C experience, tending to raise plasma density, reduce ELM frequency, and above all to recover (electron) pedestal pressure, hence global confinement, almost back to previous levels. A hitherto unrecognized role of light impurities in pedestal stability and dynamics is consequently suggested. Thirdly, while heat loads on the divertor outboard target between ELMs are successfully reduced in proportion to the radiative cooling and ELM frequency effects of N in both wall environments, more surprisingly, average power ejected by ELMs also declines in the same proportion for the ILW. Detachment between transients is simultaneously promoted. Finally, inter-ELM W sources in the ILW divertor tend to fall with N input, although core accumulation possibly due to increased particle confinement still leads to significantly less steady conditions than in all-C plasmas. This limitation of ILW H

  17. Organocatalytic Asymmetric Synthesis of Dihydrobenzoxazinones Bearing Trifluoromethylated Quaternary Stereocenters.

    PubMed

    Lou, Hengqiao; Wang, Yongtao; Jin, Enze; Lin, Xufeng

    2016-03-01

    Chiral phosphoric acid-catalyzed enantioselective aza-Friedel-Crafts reaction of trifluoromethyl benzoxazinones with pyrroles is reported. Under mild conditions, a range of enantioenriched dihydrobenzoxazinones bearing trifluoromethylated quaternary stereocenters could be obtained in good to excellent yield and ee. A remarkable fluorine effect is observed, and preliminary mechanistic studies combined with theory calculations suggest that triple-hydrogen-bonding interactions hold the transition structure rigidly and allow the bulky substituents of the catalyst to influence the enantioselectivity. PMID:26882280

  18. Quaternary fluvial archives: achievements of the Fluvial Archives Group

    NASA Astrophysics Data System (ADS)

    Bridgland, David; Cordier, Stephane; Herget, Juergen; Mather, Ann; Vandenberghe, Jef; Maddy, Darrel

    2013-04-01

    In their geomorphological and sedimentary records, rivers provide valuable archives of environments and environmental change, at local to global scales. In particular, fluvial sediments represent databanks of palaeoenvironment and palaeoclimatic (for example) of fossils (micro- and macro-), sedimentary and post-depositional features and buried soils. Well-dated sequences are of the most value, with dating provided by a wide range of methods, from radiometric (numerical) techniques to included fossils (biostratigraphy) and/or archaeological material. Thus Quaternary fluvial archives can also provide important data for studies of Quaternary biotic evolution and early human occupation. In addition, the physical disposition of fluvial sequences, be it as fragmented terrace remnants or as stacked basin-fills, provides valuable information about geomorphological and crustal evolution. Since rivers are long-term persistent features in the landscape, their sedimentary archives can represent important frameworks for regional Quaternary stratigraphy. Fluvial archives are distributed globally, being represented on all continents and across all climatic zones, with the exception of the frozen polar regions and the driest deserts. In 1999 the Fluvial Archives Group (FLAG) was established, as a working group of the Quaternary Research Association (UK), aimed at bringing together those interested in such archives. This has evolved into an informal organization that has held regular biennial combined conference and field-trip meetings, has co-sponsored other meetings and conference sessions, and has presided over two International Geoscience Programme (IGCP) projects: IGCP 449 (2000-2004) 'Global Correlation of Late Cenozoic Fluvial Deposits' and IGCP 518 (2005-2007) 'Fluvial sequences as evidence for landscape and climatic evolution in the Late Cenozoic'. Through these various activities a sequence of FLAG publications has appeared, including special issues in a variety of

  19. The impact of Quaternary Ice Ages on mammalian evolution.

    PubMed Central

    Lister, Adrian M

    2004-01-01

    The Quaternary was a time of extensive evolution among mammals. Most living species arose at this time, and many of them show adaptations to peculiarly Quaternary environments. The latter include continental northern steppe and tundra, and the formation of lakes and offshore islands. Although some species evolved fixed adaptations to specialist habitats, others developed flexible adaptations enabling them to inhabit broad niches and to survive major environmental changes. Adaptation to short-term (migratory and seasonal) habitat change probably played a part in pre-adapting mammal species to the longer-term cyclical changes of the Quaternary. Fossil evidence indicates that environmental changes of the order of thousands of years have been sufficient to produce subspeciation, but speciation has typically required one hundred thousand to a few hundred thousand years, although there are both shorter and longer exceptions. The persistence of taxa in environments imposing strong selective regimes may have been important in forcing major adaptive change. Individual Milankovitch cycles are not necessarily implicated in this process, but nor did they generally inhibit evolutionary change among mammals: many evolutionary divergences built over multiple climatic cycles. Deduction of speciation timing requires input from fossils and modern phenotypic and breeding data, to complement and constrain mitochondrial DNA coalescence dates which appear commonly to overestimate taxic divergence dates and durations of speciation. Migrational and evolutionary responses to climate change are not mutually exclusive but, on the contrary, may be synergistic. Finally, preliminary analysis suggests that faunal turnover, including an important element of speciation, was elevated in the Quaternary compared with the Neogene, at least in some biomes. Macroevolutionary species selection or sorting has apparently resulted in a modern mammalian fauna enriched with fast-reproducing and/or adaptively

  20. Quaternary Li-B-N-H Hydrides: New Hydrogen-Rich Storage Materials

    NASA Astrophysics Data System (ADS)

    Pinkerton, Frederick

    2006-03-01

    We have synthesized light metal Li-B-N-H quaternary hydrides by ball milling mixtures of LiNH2 and LiBH4 for a series of compositions (LiNH2)x(LiBH4)1-x (x = 0.33 to 0.8). We discovered a new quaternary hydride phase, referred to here as α Li-B-N-H, as the primary constituent for amide-rich (x > 0.6) compositions. Although previously tentatively identified as Li3BN2H8, its true equilibrium composition is Li4BN3H10 as determined by single crystal x-ray diffraction (XRD). Li4BN3H10 has a body-centered cubic crystal structure, space group I213 (# 199) with a = 10.68 å. In situ XRD data demonstrate that the α-phase also forms without ball milling by reacting mixed LiNH2 and LiBH4 powders at temperatures above about 95^oC. The α phase melts at about 190 C and releases hydrogen from the liquid above 250 C, forming solid Li3BN2. Using mass spectrometry residual gas analysis (RGA) we observe that NH3 is released concurrently, and the quantity of NH3 released is strongly dependent on the composition x. Maximum hydrogen release, exceeding 10 wt%, with minimum NH3 release (1-3 mole % of the evolved gas) occurs for compositions near LiNH2:LiBH4 = 2:1 (x = 0.667). Small additions of Ni, Pt, or Pd as powder or metal chloride reduce the dehydrogenation temperature by as much as 112 C, and also reduce the quantity of NH3 released by about an order of magnitude. Differential scanning calorimetry shows an endothermic melting peak above 190 C, followed by substantial exothermic heat flow above 250 C associated with hydrogen release and solidification of Li3BN2. The exothermic hydrogen release suggests that the reverse reaction is not thermodynamically favored. This new quaternary compound and its derivatives nonetheless represent promising research candidates in the search for practical on-board hydrogen storage materials.

  1. Multiple sources of alkanes in Quaternary oceanic sediment of Antarctica

    USGS Publications Warehouse

    Kvenvolden, K.A.; Rapp, J.B.; Golan-Bac, M.; Hostettler, F.D.

    1987-01-01

    Normal alkanes (n-C13n-C36), isoprenoid hydrocarbons (i-C15, i-C16, i-C18, i-C19, and i-C20) triterpanes (C27C32), and (C27C29) are present in low concentrations offshore Antarctica in near-surface, Quaternary sediment of the Wilkes Land continental margin and of the western Ross Sea. The distributions of these hydrocarbons are interpreted relative to possible sources and processes. The hydrocarbons appear to be mixtures of primary and recycled material from marine and terrigenous sources. The n-alkanes are most abundant and are characterized by two distinct populations, one of probable marine origin and the other likely from terrigenous, vascular plant sources. Because the continent of Antarctica today is devoid of higher plants, the plant-derived hydrocarbons in these offshore sediments probably came from wind-blown material and recycled Antarctic sediment that contains land-plant remains from an earlier period of time. Isoprenoid hydrocarbons are partially recycled and mainly of marine origin; the dominance of pristane over phytane suggests oxic paleoenvironmental conditions. Both modern and ancient triterpanes and steranes are present, and the distribution of these indicates a mixture of primary and recycled bacterial, algal, and possible higher-plant materials. Although the sampled sediments were deposited during the Quaternary, they apparently contain a significant component of hydrocarbons of pre-Quaternary age. ?? 1987.

  2. Protein flexibility facilitates quaternary structure assembly and evolution.

    PubMed

    Marsh, Joseph A; Teichmann, Sarah A

    2014-05-01

    The intrinsic flexibility of proteins allows them to undergo large conformational fluctuations in solution or upon interaction with other molecules. Proteins also commonly assemble into complexes with diverse quaternary structure arrangements. Here we investigate how the flexibility of individual protein chains influences the assembly and evolution of protein complexes. We find that flexibility appears to be particularly conducive to the formation of heterologous (i.e., asymmetric) intersubunit interfaces. This leads to a strong association between subunit flexibility and homomeric complexes with cyclic and asymmetric quaternary structure topologies. Similarly, we also observe that the more nonhomologous subunits that assemble together within a complex, the more flexible those subunits tend to be. Importantly, these findings suggest that subunit flexibility should be closely related to the evolutionary history of a complex. We confirm this by showing that evolutionarily more recent subunits are generally more flexible than evolutionarily older subunits. Finally, we investigate the very different explorations of quaternary structure space that have occurred in different evolutionary lineages. In particular, the increased flexibility of eukaryotic proteins appears to enable the assembly of heteromeric complexes with more unique components.

  3. Evolution of quaternary structure in a homotetrameric enzyme.

    PubMed

    Griffin, Michael D W; Dobson, Renwick C J; Pearce, F Grant; Antonio, Laurence; Whitten, Andrew E; Liew, Chu K; Mackay, Joel P; Trewhella, Jill; Jameson, Geoffrey B; Perugini, Matthew A; Gerrard, Juliet A

    2008-07-18

    Dihydrodipicolinate synthase (DHDPS) is an essential enzyme in (S)-lysine biosynthesis and an important antibiotic target. All X-ray crystal structures solved to date reveal a homotetrameric enzyme. In order to explore the role of this quaternary structure, dimeric variants of Escherichia coli DHDPS were engineered and their properties were compared to those of the wild-type tetrameric form. X-ray crystallography reveals that the active site is not disturbed when the quaternary structure is disrupted. However, the activity of the dimeric enzymes in solution is substantially reduced, and a tetrahedral adduct of a substrate analogue is observed to be trapped at the active site in the crystal form. Remarkably, heating the dimeric enzymes increases activity. We propose that the homotetrameric structure of DHDPS reduces dynamic fluctuations present in the dimeric forms and increases specificity for the first substrate, pyruvate. By restricting motion in a key catalytic motif, a competing, non-productive reaction with a substrate analogue is avoided. Small-angle X-ray scattering and mutagenesis data, together with a B-factor analysis of the crystal structures, support this hypothesis and lead to the suggestion that in at least some cases, the evolution of quaternary enzyme structures might serve to optimise the dynamic properties of the protein subunits.

  4. Quaternary diversification in a sexual Holarctic zooplankter, Daphnia galeata.

    PubMed

    Ishida, Seiji; Taylor, Derek J

    2007-02-01

    The effects of Quaternary glacial range partitioning on the diversification of Holarctic biota remain unclear. Glacial refugial lineages may form vicariant species, hybrid products, or merge after secondary contact. Here, we assess the effects of Quaternary glaciation on a Holarctic sexual zooplankter, Daphnia galeata, with apparently marked dispersal capacity and a widespread hybrid lineage in the New World. We collected samples of this species from 148 Holarctic lakes, analysed the nuclear and mitochondrial gene sequences, and tested predictions for hypotheses that account for the origin and spread of the New World D. galeata. We detected five nuclear phylogroups and four mitochondrial phylogroups, most of which were restricted to either the New World or the Old World. The oldest mitochondrial phylogroup was restricted to Japan. One major mitochondrial clade was distributed throughout the Holarctic, but only four haplotypes were shared among continents, and analysis of molecular variance indicated significant structure at the continental level. Haplotype sharing among continents could largely be attributed to anthropogenic introductions. Mismatch distributions, haplotype networks, phylogenetic trees, longitudinal haplotype diversity erosion and coalescence analyses are consistent with colonization from an Old World and a New World refugium. Our nuclear and mitochondrial DNA sequence evidence supports the hypothesis that the New World D. galeata underwent introgression with Daphnia dentifera, with dispersal being enhanced by glaciation. We conclude that Quaternary glaciation had a pronounced effect on the diversification of a Holarctic sexual zooplankter.

  5. Quaternary diversification in a sexual Holarctic zooplankter, Daphnia galeata.

    PubMed

    Ishida, Seiji; Taylor, Derek J

    2007-02-01

    The effects of Quaternary glacial range partitioning on the diversification of Holarctic biota remain unclear. Glacial refugial lineages may form vicariant species, hybrid products, or merge after secondary contact. Here, we assess the effects of Quaternary glaciation on a Holarctic sexual zooplankter, Daphnia galeata, with apparently marked dispersal capacity and a widespread hybrid lineage in the New World. We collected samples of this species from 148 Holarctic lakes, analysed the nuclear and mitochondrial gene sequences, and tested predictions for hypotheses that account for the origin and spread of the New World D. galeata. We detected five nuclear phylogroups and four mitochondrial phylogroups, most of which were restricted to either the New World or the Old World. The oldest mitochondrial phylogroup was restricted to Japan. One major mitochondrial clade was distributed throughout the Holarctic, but only four haplotypes were shared among continents, and analysis of molecular variance indicated significant structure at the continental level. Haplotype sharing among continents could largely be attributed to anthropogenic introductions. Mismatch distributions, haplotype networks, phylogenetic trees, longitudinal haplotype diversity erosion and coalescence analyses are consistent with colonization from an Old World and a New World refugium. Our nuclear and mitochondrial DNA sequence evidence supports the hypothesis that the New World D. galeata underwent introgression with Daphnia dentifera, with dispersal being enhanced by glaciation. We conclude that Quaternary glaciation had a pronounced effect on the diversification of a Holarctic sexual zooplankter. PMID:17257114

  6. Quaternary diversification in European alpine plants: pattern and process.

    PubMed Central

    Kadereit, Joachim W; Griebeler, Eva Maria; Comes, Hans Peter

    2004-01-01

    Molecular clock approaches applied previously to European alpine plants suggest that Primula sect. Auricula, Gentiana sect. Ciminalis and Soldanella diversified at the beginning of the Quaternary or well within this period, whereas Globularia had already started diversifying in the (Late-)Tertiary. In the first part of this paper we present evidence that, in contrast to Globularia and Soldanella, the branching patterns of the molecular internal transcribed spacer phylogenies of both Primula and Gentiana are incompatible with a constant-rates birth-death model. In both of these last two taxa, speciation probably decreased through Quaternary times, perhaps because of some niche-filling process and/or a decrease in specific range size. In the second part, we apply nonlinear regression analyses to the lineage-through-time plots of P. sect. Auricula to test a range of capacity-dependent models of diversification, and the effect of Quaternary climatic oscillations on diversification and extinction. At least for one major clade of sect. Auricula there is firm evidence that both diversification and extinction are a function of temperature. Intriguingly, temperature appears to be correlated positively with extinction, but negatively with diversification. This suggests that diversification did not take place, as previously assumed, in geographical isolation in high-altitude interglacial refugia, but rather at low altitudes in geographically isolated glacial refugia. PMID:15101582

  7. Anticholinesterase inhibitory activity of quaternary alkaloids from Tinospora crispa.

    PubMed

    Yusoff, Mashitah; Hamid, Hazrulrizawati; Houghton, Peter

    2014-01-01

    Quaternary alkaloids are the major alkaloids isolated from Tinospora species. A previous study pointed to the necessary presence of quaternary nitrogens for strong acetylcholinesterase (AChE) inhibitory activity in such alkaloids. Repeated column chromatography of the vine of Tinospora crispa extract led to the isolation of one new protoberberine alkaloid, 4,13-dihydroxy-2,8,9-trimethoxydibenzo[a,g]quinolizinium (1), along with six known alkaloids-dihydrodiscretamine (2), columbamine (3), magnoflorine (4), N-formylannonaine (5), N-formylnornuciferine (6), and N-trans-feruloyltyramine (7). The seven compounds were isolated and structurally elucidated by spectroscopic analysis. Two known alkaloids, namely, dihydrodiscretamine and columbamine are reported for the first time for this plant. The compounds were tested for AChE inhibitory activity using Ellman's method. In the AChE inhibition assay, only columbamine (3) showed strong activity with IC50 48.1 µM. The structure-activity relationships derived from these results suggest that the quaternary nitrogen in the skeleton has some effect, but that a high degree of methoxylation is more important for acetylcholinesterase inhibition. PMID:24448061

  8. Phylogeography of Rhodiola kirilowii (Crassulaceae): a story of Miocene divergence and quaternary expansion.

    PubMed

    Zhang, Jian-Qiang; Meng, Shi-Yong; Rao, Guang-Yuan

    2014-01-01

    The evolution and current distribution of the Sino-Tibetan flora have been greatly affected by historical geological events, such as the uplift of the Qinghai-Tibetan Plateau (QTP), and Quaternary climatic oscillations. Rhodiola kirilowii, a perennial herb with its distribution ranging from the southeastern QTP and the Hengduan Mountains (HM) to adjacent northern China and central Asia, provides an excellent model to examine and disentangle the effect of both geological orogeny and climatic oscillation on the evolutionary history of species with such distribution patterns. We here conducted a phylogeographic study using sequences of two chloroplast fragments (trnL-F and trnS-G) and internal transcribed spacers in 29 populations of R. kirilowii. A total of 25 plastid haplotypes and 12 ITS ribotypes were found. Molecular clock estimation revealed deep divergence between the central Asian populations and other populations from the HM and northern China; this split occurred ca. 2.84 million year ago. The majority of populations from the mountains of northern China were dominated by a single haplotype or ribotype, while populations of the HM harbored both high genetic diversity and high haplotype diversity. This distribution pattern indicates that HM was either a diversification center or a refugium for R. kirilowii during the Quaternary climatic oscillations. The present distribution of this species on mountains in northern China may have resulted from a rapid glacial population expansion from the HM. This expansion was confirmed by the mismatch distribution analysis and negative Tajima's D and Fu's FS values, and was dated to ca. 168 thousand years ago. High genetic diversity and population differentiation in both plastid and ITS sequences were revealed; these imply restricted gene flow between populations. A distinct isolation-by-distance pattern was suggested by the Mantel test. Our results show that in old lineages, populations may harbour divergent genetic forms

  9. Factors controlling Pliocene-Quaternary sedimentation on the Gulf of Cadiz Continental Slope, Spain

    SciTech Connect

    Baraza, J.; Maldonado, A. ); Nelson, C.H. )

    1990-05-01

    The Pliocene-Quaternary sedimentation on the Gulf of Cadiz continental slope records an interaction between the tectonics responsible for a complex bathymetry, and the Mediterranean outflow undercurrent developed after the opening of the Gibraltar Strait at the end of the Miocene. During periods of low sea level, sedimentation was controlled mainly by changes in the sediment supply from the various rivers that feed the area. During high sea level, periods like the present, deposition is controlled mainly by the Mediterranean undercurrent. The Mediterranean undercurrent flows out from the Strait of Gibraltar toward the northwest and impinges on the Cadiz continental slope at 300- to 500-m depths. Flows are fastest near the Strait of Gibraltar (as much as 200 m/sec) and slow to 10-20 m/sec westward Portugal. The gradual decrease in undercurrent speed from the Strait of Gibraltar to the center of the Gulf of Cadiz results in a westward change from erosional to depositional characteristics on the upper continental slope. Erosion in the southeastern part of the Gulf is characterized by exposed bed rock on the sea floor and by erosional truncation of reflectors on sea-floor slopes. In contrast, several prograding shelf-break types and slope configurations occur in the west, showing the influence of tectonic subsidence, diapir uplift and sediment supply on the Pliocene-Quaternary sedimentation. At middle slope depths, high-energy depositional features, such as cut-and-fill structures, are observed in seismic profiles. Energy decreasing bed-form fields, from east to west, are shown in profiles and sonographic of the most sufficial units on the deep platforms. In addition, sediment drift bodies deposit against basement diapiric ridges near the canyon-ridge central area.

  10. Quaternary glaciations: from observations to theories

    NASA Astrophysics Data System (ADS)

    Paillard, Didier

    2015-01-01

    Ice ages are known since the mid-nineteenth century. From the beginning, they have been at the center of theories of climate and climate change. Still, the mechanisms behind these large amplitude oscillations remain poorly understood. In order to position our current knowledge of glacial-interglacial cycles, it is useful to present how the notion of climate change appeared in the XIXth century with the discovery of glacial periods, and how the two main theories, the astronomical one and the geochemical one, emerged progressively both from sound physical principles but also from extravagant ideas. Major progresses in geochemistry in the XXth century led first to the firm evidence of an astronomical pacemaker of these cycles thanks to the accumulation of paleoceanographic data. Still, the Milankovitch's theory predicts an ice age cyclicity of about 41,000 years, while the major periodicity found in the records is 100,000 yr. Besides, ice cores from Antarctica proved unambiguously that the atmospheric carbon dioxide was lower during glacial periods. Even more importantly, during the last termination, the atmospheric pCO2 increases significantly by about 50 ppm, several millenia before any important change in continental ice volume. This fact, together with many other pieces of information, strongly suggests an active role of greenhouse gases in the ice age problem, at least during deglaciations. Since terminations are precisely at the heart of the 100-ka problem, we need to formulate a new synthesis of the astronomical and geochemical theories in order to unravel this almost two-century-old question of ice ages. The foundations of such a theory have already been put forward, and its predictions appear in surprisingly good agreement with many recent observations.

  11. Polycationic antimicrobial dendrimers: a comparison of alkyl pyridinium,quaternary ammonium, quaternary phosphonium and tertiary sulfonium salts

    NASA Astrophysics Data System (ADS)

    Chen, Chris; Cooper, Stuart

    2000-03-01

    Polycationic biocides usually kill bacteria through the interactions of the positively charged head groups with negatively charged bacteria and the interactions of the hydrophobic segments with phospholipid cell membranes, which implies that high local charge densities and a large number of hydrophobic groups would lead to enhanced biocidal potency. The advent of dendrimers offers us the first-ever opportunity to achieve the desired high local density. We have demonstrated that dimethyl dodecyl ammonium chloride functionalized polypropylene imine dendrimers are over 100 times more potent than their small molecule ounterparts. In this study, quaternary ammonium, quaternary phosphonium, alkyl pyridinium and tertiary sulfonium salts based on polypropylene imine dendrimers have been synthesized and characterized. Their antimicrobial properties have been quantified with a novel bioluminescence method. The structure-activity relationship of these polycationic dendrimers has also been investigated to elucidate the molecular mechanism for the enhanced antimicrobial effects.

  12. Quaternary coastal evolution of Oman (Arabian Peninsula) - a quantitative approach

    NASA Astrophysics Data System (ADS)

    Hoffmann, G.; Rupprechter, M.; Roepert, A.; Quraishi, K. Al; Balushi, N. Al; Grützner, C.; Reicherter, K.

    2012-04-01

    The paper reviews the Quaternary coastal evolution of Oman. Emphasise is put on quantifying the different forcing factors. The plate tectonic setting, the Quaternary climate evolution, the sea-level history and the impact of natural hazards are identified as key factors of coastal evolution. The Arabian Plate is characterized by a northward movement forming a continent-continent collision zone in the west and the Makran Subduction Zone in the east. As a result differential land movement is observable in Oman. The Quaternary climate evolution is well understood. Besides other proxies notably spelothems and aeolian deposits allow to draw a consistent picture. It is understood that changes in the position of the intertropical convergence zone result in intensity-changes of the summer monsoon. These changes are related to global atmospheric circulation patterns. Data on the sea-level history are sparse; despite general assumptions of a sea-level lowstand, correlating with the last glacial maximum, resulting in terrestrial conditions within the Arabian Gulf. Furthermore, a mid-Holocene sea level highstand in the range of +2m is documented in several locations. The coastlines of Oman are affected by tsunami and hurricanes. However, almost no instrumental or historical data on the impact of such natural hazards are available due to the isolation of the country in the past. Several Quaternary deposits have been investigated in a reconnaissance survey. There is sound geological evidence for a tsunami to have affected the coastline in 1945, with the possibility of older tsunami events being also recorded in the geological record. There is strong evidence of differential land movement along the coastline; locally indicated by marine terraces in elevations of up to 400m (Rupprechter at al. 2012). By quantifying the differential land movement for numerous sites, the sea-level history will be revealed. Ultimately the data will be utilized to form the base of a modeling approach

  13. The Quaternary adakite distribution of Kyushu Island, Ryukyu Arc, Japan

    NASA Astrophysics Data System (ADS)

    Shibata, T.; Yoshikawa, M.; Takemura, K.

    2011-12-01

    The Quaternary volcanoes are widely distributed in Kyusu Island, Japan. Philippine Sea plate is subducting beneath Kyushu. Clear distribution of deep seismic foci is observed below the Quaternary volcanoes in southern area, but not in northern area. Notsu et al. (1990, JVGR) examined the contribution of subduction to the magma source, and emphasized that no slab derived material is observed in northern area from Sr isotopic compositions. Volcanic activity similar to the within-plate type volcanism has been also emphasized for the magma genesis of this area (e.g. Kita et al, 2001, JVGR). However, we found adakitic rocks, which show high Sr/Y ratios and low Y concentrations (e.g. Defant and Drummond, 1990, Nature) from some Quaternary volcanoes in north Kyushu on the basis of published data (Otha et al, 1990, GANKO; Itoh, 1990, GANKO). Therefore, the magma genesis is still controversial. We studied lateral variations of Sr, Nd and Pb isotopic and trace element compositions for Quaternary volcanics from Kyushu to investigate the magma genesis. From the results, a clear variation of Sr/Y ratio, decreasing from north to south, is observed along the volcanic front. Some of the Sr/Y ratio of the most northern part of Kyusu shows the value >100. The all analyzed Pb isotope compositions show a single liner trend in 208Pb/204Pb v.s. 206Pb/204Pb diagram. The liner trend of Pb isotope ratios can be explained by the binary mixing of the Shikoku Basin basalt and tereginious sediment which might be a constituent of the subducting slab. The similar binary mixing relationships are found in Sr and Nd isotopic systematics. The isotopic characteristics of the Quaternary magma in Kyushu can be explained by the magma generation process of island arc, in spite of the lack of deep seismic foci in northern area. It is considered that high and low Sr/Y ratios suggest the contributions of partial melt in the north and aqueous fluid derived from subducting slab in the south, respectively. If

  14. Quaternary tectonic faulting in the Eastern United States

    USGS Publications Warehouse

    Wheeler, R.L.

    2006-01-01

    Paleoseismological study of geologic features thought to result from Quaternary tectonic faulting can characterize the frequencies and sizes of large prehistoric and historical earthquakes, thereby improving the accuracy and precision of seismic-hazard assessments. Greater accuracy and precision can reduce the likelihood of both underprotection and unnecessary design and construction costs. Published studies proposed Quaternary tectonic faulting at 31 faults, folds, seismic zones, and fields of earthquake-induced liquefaction phenomena in the Appalachian Mountains and Coastal Plain. Of the 31 features, seven are of known origin. Four of the seven have nontectonic origins and the other three features are liquefaction fields caused by moderate to large historical and Holocene earthquakes in coastal South Carolina, including Charleston; the Central Virginia Seismic Zone; and the Newbury, Massachusetts, area. However, the causal faults of the three liquefaction fields remain unclear. Charleston has the highest hazard because of large Holocene earthquakes in that area, but the hazard is highly uncertain because the earthquakes are uncertainly located. Of the 31 features, the remaining 24 are of uncertain origin. They require additional work before they can be clearly attributed either to Quaternary tectonic faulting or to nontectonic causes. Of these 24, 14 features, most of them faults, have little or no published geologic evidence of Quaternary tectonic faulting that could indicate the likely occurrence of earthquakes larger than those observed historically. Three more features of the 24 were suggested to have had Quaternary tectonic faulting, but paleoseismological and other studies of them found no evidence of large prehistoric earthquakes. The final seven features of uncertain origin require further examination because all seven are in or near urban areas. They are the Moodus Seismic Zone (Hartford, Connecticut), Dobbs Ferry fault zone and Mosholu fault (New York

  15. Digital release of the Alaska Quaternary fault and fold database

    NASA Astrophysics Data System (ADS)

    Koehler, R. D.; Farrell, R.; Burns, P.; Combellick, R. A.; Weakland, J. R.

    2011-12-01

    The Alaska Division of Geological & Geophysical Surveys (DGGS) has designed a Quaternary fault and fold database for Alaska in conformance with standards defined by the U.S. Geological Survey for the National Quaternary fault and fold database. Alaska is the most seismically active region of the United States, however little information exists on the location, style of deformation, and slip rates of Quaternary faults. Thus, to provide an accurate, user-friendly, reference-based fault inventory to the public, we are producing a digital GIS shapefile of Quaternary fault traces and compiling summary information on each fault. Here, we present relevant information pertaining to the digital GIS shape file and online access and availability of the Alaska database. This database will be useful for engineering geologic studies, geologic, geodetic, and seismic research, and policy planning. The data will also contribute to the fault source database being constructed by the Global Earthquake Model (GEM), Faulted Earth project, which is developing tools to better assess earthquake risk. We derived the initial list of Quaternary active structures from The Neotectonic Map of Alaska (Plafker et al., 1994) and supplemented it with more recent data where available. Due to the limited level of knowledge on Quaternary faults in Alaska, pre-Quaternary fault traces from the Plafker map are shown as a layer in our digital database so users may view a more accurate distribution of mapped faults and to suggest the possibility that some older traces may be active yet un-studied. The database will be updated as new information is developed. We selected each fault by reviewing the literature and georegistered the faults from 1:250,000-scale paper maps contained in 1970's vintage and earlier bedrock maps. However, paper map scales range from 1:20,000 to 1:500,000. Fault parameters in our GIS fault attribute tables include fault name, age, slip rate, slip sense, dip direction, fault line type

  16. Improved low temperature performance of lithium ion cells with quaternary carbonate-based electrolytes

    NASA Technical Reports Server (NTRS)

    Smart, M. C.; Ratnakumar, B. V.; Whitcanack, L. D.; Chin, K. B.; Surampudi, S.; Croft, H.; Tice, D.; Staniewicz, R.

    2002-01-01

    In order to enable future missions involving the exploration of the surface of Mars with Landers and Rovers, NASA desires long life, high energy density rechargeable batteries which can operate well at very low temperature (down to 40(deg)C). Lithium-ion technology has been identified as being the most promising chemistry, due to high gravimetric and volumetric energy densities, as well as, long life characteristics. However, the state-of-art (SOA) technology is not sufficient to meet the needs of many applications that require excellent low temperature capabilities. To further improve this technology, work at JF'L has been focused upon developing electrolytes that result in lithium-ion cells with wider temperature ranges of operation. These efforts have led to the identification of a number of ternary and quaternary, all carbonate-based electrolytes that have been demonstrated to result in improved low temperature performance in experimental three-electrode MCMB carbon/LiNio.sCoo.zOz cells. A number of electrochemical characterization techniques were performed on these cells (i.e., Tafel polarization measurements, linear polarization measurements, and electrochemical impedance spectroscopy (EIS)) to further enhance our understanding of the performance limitations at low temperature. The most promising electrolyte formulations, namely 1 .O M LiPF6EC+DEC+DMC+EMC (1 : 1: 1 :2 v/v) and 1 .O M LiPF6 EC+DEC+DMC+EMC (1 : 1 : 1 :3 v/v), were incorporated into SAFT prototype DD-size (9 Ahr) lithium- cells for evaluation. A number of electrical tests were performed on these cells, including rate characterization as a function of temperature, cycle life characterization at different temperatures, as well as, many mission specific characterization test to determine their viability to enable future missions to Mars. Excellent performance was observed with the prototype DD-size cells over a wide temperature range (-50 to 4OoC), with high specific energy being delivered at very

  17. Cosmogenic 36Cl ages of Quaternary basalt flows in the Mojave Desert, California, USA

    NASA Astrophysics Data System (ADS)

    Phillips, Fred M.

    2003-07-01

    Basalt flows provide excellent opportunities for calibration and intercomparison of Quaternary dating methods, remote sensing methods, and rates of geomorphic processes. The immediate motivation for this study was to provide chronology for a blind test of the utility of rock varnish microstratigraphy as an indicator of the age of flow emplacement. Five basaltic eruptive centers in the Mojave Desert of California were sampled for cosmogenic 36Cl analysis. Multiple samples were taken from most centers and, with one exception, produced good agreement. Assuming a surficial erosion rate of 1 mm/kyr -1, the flows yielded the following ages: Amboy Crater, 79±5 ka; Pisgah Crater, 22.5±1.3 ka; Cima field, I-Cone, 27±1.3 ka; Cima field, A-Cone, 21±1.6 ka and 11.5±1.5 ka; Cima field, flow of unidentified origin, 46±2 ka. The ages from the Cima I and A cones are in good agreement with previous cosmogenic 3He dating. Ages from the three previously undated flows are significantly older than previous estimates based on flow appearance. Tanzhou Liu performed varnish microstratigraphic analysis on samples collected from the same sites. His results were submitted for publication without knowledge of the 36Cl ages. His age estimates agree well with the 36Cl ages for the three previously undated flows, strongly supporting the validity of varnish microstratigraphy as a chronological correlation tool.

  18. Database and Map of Quaternary Faults and Folds in Peru and its Offshore Region

    USGS Publications Warehouse

    Machare, Jose; Fenton, Clark H.; Machette, Michael N.; Lavenu, Alain; Costa, Carlos; Dart, Richard L.

    2003-01-01

    This publication consists of a main map of Quaternary faults and fiolds of Peru, a table of Quaternary fault data, a region inset map showing relative plate motion, and a second inset map of an enlarged area of interest in southern Peru. These maps and data compilation show evidence for activity of Quaternary faults and folds in Peru and its offshore regions of the Pacific Ocean. The maps show the locations, ages, and activity rates of major earthquake-related features such as faults and fault-related folds. These data are accompanied by text databases that describe these features and document current information on their activity in the Quaternary.

  19. Breakdown of the consent process at a quaternary medical center: our full disclosure.

    PubMed

    Fairfax, Lindsay M; Christmas, A Britton; Norton, H James; Jacobs, David G

    2012-08-01

    Circumstances may arise in the intensive care unit (ICU) when the physician is unable to obtain informed consent. We undertook this study to determine the variations in the consent process. An anonymous survey was distributed to all critical care nurses (RN), resident physicians (RES), advanced practitioners (AP), and attending physicians (ATT). Participants were asked to describe the risks of nine common ICU procedures (central venous line, peripherally inserted central catheter, bronchoscopy, tube thoracostomy, tracheostomy, vena cava filter, angioembolization, image-guided drainage, and percutaneous endoscopic gastrostomy tube). Participants were also asked which member of the healthcare team should obtain consent. All groups were compared with ATT responses and RN responses were compared with the remaining groups. The response rate was 134 of 610 participants (22%) with 51 per cent RN (n = 68), 17 per cent RES (n = 23), 7 per cent AP (n = 9), and 25 per cent ATT (n = 34). Compared with ATT, RN assessment of important risks varied significantly for eight of nine procedures. RES responses varied in three procedures. A minority believed that nurses should obtain consent. However, many physicians (34% ATT and 27% RES) denied having informed consent discussions with 50 per cent or more of their patients. This study has exposed a wide variation in consent practices. Future efforts to standardize consent processes are needed to protect patients and physicians.

  20. Computer centers

    NASA Astrophysics Data System (ADS)

    The National Science Foundation has renewed grants to four of its five supercomputer centers. Average annual funding will rise from $10 million to $14 million so facilities can be upgraded and training and education expanded. As cooperative projects, the centers also receive money from states, universities, computer vendors and industry. The centers support research in fluid dynamics, atmospheric modeling, engineering geophysics and many other scientific disciplines.

  1. Stereoselective Domino Carbocyclizations of γ- and δ-Cyano-N-tosylhydrazones with Alkenylboronic Acids with Formation of Two Different C(sp(3))-C(sp(2)) Bonds on a Quaternary Stereocenter.

    PubMed

    Plaza, Manuel; Valdés, Carlos

    2016-09-21

    A novel strategy for the synthesis of functionalized carbocycles is defined, through the cascade carbocyclization of alkenylboronic acids with δ- or γ-cyano-N-tosylhydrazones. In the reaction, two C(sp(3))-C(sp(2)) bonds are formed on the former hydrazonic carbon generating an all-carbon quaternary stereocenter, and leading to cyclic ketones featuring an alkenyl side chain with complete diastereoselectivity. The processes are conducted under very simple experimental conditions, only in the presence of K2CO3, in 1,4-dioxane as solvent and under microwave irradiation, and have been applied for the synthesis of a wide structural variety of fused cyclopentanones and cyclohexanones. Moreover, the versatility of this methodology has been demonstrated in the structural modification of androsterone. PMID:27618127

  2. Skills Center.

    ERIC Educational Resources Information Center

    Canter, Patricia; And Others

    The services of the Living Skills Center for the Visually Handicapped, a habilitative service for blind young adults, are described. It is explained that the Center houses its participants in their own apartments in a large complex and has served over 70 young people in 4 years. The evaluation section describes such assessment instruments as an…

  3. Tertiary and Quaternary tectonic faulting in southernmost Illinois

    USGS Publications Warehouse

    Nelson, W.J.; Denny, F.B.; Devera, J.A.; Follmer, L.R.; Masters, J.M.

    1997-01-01

    Tertiary and/or Quaternary tectonic faulting is documented in three areas of southernmost Illinois: the Fluorspar Area Fault Complex (FAFC) in Pope and Massac Counties, the Ste. Genevieve Fault Zone (SGFZ) in Alexander and Union Counties, and the Commerce Fault Zone (CFZ) in Alexander County. In the FAFC, faults that strike NE and NNE displace Mounds Gravel (late Miocene to early Pleistocene) and, locally, the Metropolis terrace gravel (Pleistocene; pre-Woodfordian). No Woodfordian or younger deposits are deformed. Faults typically outline narrow, linear grabens that formed under tension with a component of strike slip. North-south to NW-trending vertical faults near the southeast end of the SGFZ displace Eocene sediments. Again, faults outline narrow grabens and show indications of strike slip. Deformed Quaternary sediments have not been observed. The CFZ, which trends northeast, displaces Mounds Gravel in Illinois and units as young as Peoria Silt (Woodfordian) in Missouri. Quaternary movement has been interpreted as right-lateral strike-slip. The CFZ coincides with a subtle gravity and magnetic lineament and seems to reflect a major feature in the basement. Surface expression in Illinois is subtle, but mafic and ultramafic intrusions, hydrothermal alteration and small faults align with the Commerce geophysical lineament. Earthquake foci in Missouri and Illinois lie on or close to the CFZ; some focal mechanisms fit the fault trend. Among these structures, only the CFZ exhibits slip that conforms to the current stress field (principal compressive stress axis E-W to ENE-WSW). Possibly, the stress field changed during Neogene time. Alternatively, high fluid pressures or local stress concentrations may have induced slip on less favorably oriented fractures. Tighter constraints are needed on timing, magnitude, and direction of Neogene displacement. ?? 1997 Elsevier Science B.V.

  4. An aminostratigraphy for the British Quaternary based on Bithynia opercula

    PubMed Central

    Penkman, Kirsty E.H.; Preece, Richard C.; Bridgland, David R.; Keen, David H.; Meijer, Tom; Parfitt, Simon A.; White, Tom S.; Collins, Matthew J.

    2013-01-01

    Aminostratigraphies of Quaternary non-marine deposits in Europe have been previously based on the racemization of a single amino acid in aragonitic shells from land and freshwater molluscs. The value of analysing multiple amino acids from the opercula of the freshwater gastropod Bithynia, which are composed of calcite, has been demonstrated. The protocol used for the isolation of intra-crystalline proteins from shells has been applied to these calcitic opercula, which have been shown to more closely approximate a closed system for indigenous protein residues. Original amino acids are even preserved in bithyniid opercula from the Eocene, showing persistence of indigenous organics for over 30 million years. Geochronological data from opercula are superior to those from shells in two respects: first, in showing less natural variability, and second, in the far better preservation of the intra-crystalline proteins, possibly resulting from the greater stability of calcite. These features allow greater temporal resolution and an extension of the dating range beyond the early Middle Pleistocene. Here we provide full details of the analyses for 480 samples from 100 horizons (75 sites), ranging from Late Pliocene to modern. These show that the dating technique is applicable to the entire Quaternary. Data are provided from all the stratotypes from British stages to have yielded opercula, which are shown to be clearly separable using this revised method. Further checks on the data are provided by reference to other type-sites for different stages (including some not formally defined). Additional tests are provided by sites with independent geochronology, or which can be associated with a terrace stratigraphy or biostratigraphy. This new aminostratigraphy for the non-marine Quaternary deposits of southern Britain provides a framework for understanding the regional geological and archaeological record. Comparison with reference to sites yielding independent geochronology, in

  5. Precise timing and rate of massive late Quaternary soil denudation

    NASA Astrophysics Data System (ADS)

    Cooke, M. Jennifer; Stern, Libby A.; Banner, Jay L.; Mack, Lawrence E.; Stafford, Thomas W., Jr.; Toomey, Rickard S., III

    2003-10-01

    Strontium isotopes are a unique tool to study soil-erosion dynamics. Changes in Sr isotope ratios (87Sr/86Sr) provide a record of late Quaternary landscape denudation of the Edwards Plateau of central Texas, United States. The use of Sr isotopes as a tracer for soil erosion is based on the observation that, in central Texas, the 87Sr/86Sr ratio of soil correlates with soil thickness. Plants and animals express the 87Sr/86Sr ratio of exchangeable Sr in the soil. Therefore, we use changes in Sr isotope ratios through a well-dated stratigraphic sequence of fossil plants and animals in Hall's Cave, Kerr County, Texas, as a proxy for temporal changes in soil thickness. By using this record we are able to characterize late Quaternary climate-driven soil-erosion dynamics on the Edwards Plateau. We find that continuous erosion removed at least 180 cm of soil at a constant minimum rate of 11 cm/k.y.; this continuous phase of erosion ended ca. 5 ka. The Sr isotope record of soil erosion is consistent with late Quaternary environmental change in central Texas that has been independently modeled by using local and regional climate records. However, the rate of this climate-driven soil-erosion event was an order of magnitude slower than recent soil erosion caused by human land use. These results link erosion to century- to millennial-scale climate change and are cautionary evidence that even greater landscape degradation may result from coincident climatic variability and anthropogenic influences.

  6. Quaternary geology and waste disposal in South Norfolk, England

    NASA Astrophysics Data System (ADS)

    Gray, J. M.

    South Norfolk is dominated by the till plain of the Anglian Glaciation in eastern England, and therefore there are very few disused gravel pits and quarries suitable for the landfilling of municipal waste. Consequently, in May 1991, Norfolk County Council applied for planning permission to develop an above ground or 'landraise' waste disposal site at a disused U.S. World War II Airfield at Hardwick in South Norfolk. The proposal involved excavating a pit 2-4 m deep into the Lowestoft Till and overfilling it to create a hill of waste up to 10 m above the existing till plain. In general, leachate containment was to be achieved by utilising the relatively low permeability till on the floor of the site, but with reworking of the till around the site perimeter because of sand lenses in the upper part of the till. This paper examines three aspects of the proposal and the wider issues relating to Quaternary geology and waste disposal planning in South Norfolk: (i) the suitability of the till as a natural leachate containment system; (ii) the appropriateness of the landraise landform; and (iii) alternative sites. A Public Inquiry into the proposals was held in January/February 1993 and notification of refusal of planning permission was published in August 1993. Among the grounds for refusal were an inadequate knowledge of the site's geology and hydrogeology and the availability of alternative sites. The paper concludes by stressing that a knowledge of Quaternary geology is crucial to both the planning and design of landfill sites in areas of glacial/Quaternary sediments.

  7. A Novel Route to Recognizing Quaternary Ammonium Cations Using Electrospray Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Shackman, Holly M.; Ding, Wei; Bolgar, Mark S.

    2015-01-01

    Characterizing and elucidating structures is a commonplace and necessary activity in the pharmaceutical industry with mass spectrometry and NMR being the primary tools for analysis. Although many functional groups are readily identifiable, quaternary ammonium cations have proven to be difficult to unequivocally identify using these techniques. Due to the lack of an N-H bond, quaternary ammonium groups can only be detected in the 1H NMR spectra by weak signals generated from long-range 14N-H coupling, which by themselves are inconclusive evidence of a quaternary ammonium functional group. Due to their low intensity, these signals are frequently not detected. Additionally, ions cannot be differentiated in a mass spectrum as an M+ or [M + H]+ ion without prior knowledge of the compound's structure. In order to utilize mass spectrometry as a tool for determining this functionality, ion cluster formation of quaternary ammonium cations and non-quaternary amines was studied using electrospray ionization. Several mobile phase modifiers were compared; however, the addition of small amounts of trifluoroacetic acid proved superior in producing characteristic and intense [M +2TFA]- clusters for compounds containing quaternary ammonium cations when using negative electrospray. By fragmenting this characteristic ion using CID, nearly all compounds studied could be unambiguously identified as containing a quaternary ammonium cation or a non-quaternary amine attributable to the presence (non-quaternary amine) or absence (quaternary ammonium cation) of the resulting [2TFA + H]- ion in the product spectra. This method of analysis provides a rapid, novel, and reliable technique for indicating the presence of quaternary ammonium cations in order to aid in structural elucidation.

  8. A novel route to recognizing quaternary ammonium cations using electrospray mass spectrometry.

    PubMed

    Shackman, Holly M; Ding, Wei; Bolgar, Mark S

    2015-01-01

    Characterizing and elucidating structures is a commonplace and necessary activity in the pharmaceutical industry with mass spectrometry and NMR being the primary tools for analysis. Although many functional groups are readily identifiable, quaternary ammonium cations have proven to be difficult to unequivocally identify using these techniques. Due to the lack of an N-H bond, quaternary ammonium groups can only be detected in the (1)H NMR spectra by weak signals generated from long-range (14)N-H coupling, which by themselves are inconclusive evidence of a quaternary ammonium functional group. Due to their low intensity, these signals are frequently not detected. Additionally, ions cannot be differentiated in a mass spectrum as an M(+) or [M + H](+) ion without prior knowledge of the compound's structure. In order to utilize mass spectrometry as a tool for determining this functionality, ion cluster formation of quaternary ammonium cations and non-quaternary amines was studied using electrospray ionization. Several mobile phase modifiers were compared; however, the addition of small amounts of trifluoroacetic acid proved superior in producing characteristic and intense [M +2TFA](-) clusters for compounds containing quaternary ammonium cations when using negative electrospray. By fragmenting this characteristic ion using CID, nearly all compounds studied could be unambiguously identified as containing a quaternary ammonium cation or a non-quaternary amine attributable to the presence (non-quaternary amine) or absence (quaternary ammonium cation) of the resulting [2TFA + H](-) ion in the product spectra. This method of analysis provides a rapid, novel, and reliable technique for indicating the presence of quaternary ammonium cations in order to aid in structural elucidation.

  9. Stegomastodon associated with Mammuthus in Arizona during the Quaternary

    NASA Astrophysics Data System (ADS)

    Madden, Cary T.

    1986-09-01

    The gomphothere, Stegomastodon, is the most morphologically progressive non-elephant proboscidean in North America. Prior to the appearance of mammoths during the earliest Pleistocene, stegomastodonts held niches later occupied by those elephants. Two proboscidean specimens from near Taylor, Arizona, show that elephant-like Stegomastodon coexisted with Mammuthus in the southwestern United States during the Quaternary. Other associations of Stegomastodon and Mammuthus are known from the early and middle Pleistocene of Texas and the early Pleistocene of Nebraska. The mammoth from the Taylor locality is the oldest known from Arizona.

  10. Mutagenic activity of quaternary ammonium salt derivatives of carbohydrates

    PubMed Central

    Sikora, Karol; Woziwodzka, Anna; Piosik, Jacek; Podgórska, Beata

    2016-01-01

    Summary This paper presents a study on a series of quaternary ammonium salt (QAS) derivatives of glucopyranosides with an elongated hydrophobic hydrocarbon chain. The new N-[6-(β-D-glucopyranosyloxy)hexyl]ammonium bromides and their O-acetyl derivatives were analyzed via 1H and 13C NMR spectroscopy. The mutagenic activity of the newly synthesized QAS was investigated using two different techniques: The Vibrio harveyi luminescence assay and the Ames test. The obtained results support previous findings contesting QAS safety and indicate that QAS, specifically pyridinium derivatives, might be mutagenic. PMID:27559394

  11. Quaternary geology of the Channeled Scabland and adjacent areas

    NASA Technical Reports Server (NTRS)

    Baker, V. R.

    1978-01-01

    The quaternary history of the channeled scabland is characterized by discrete episodes of catastrophic flooding and prolonged periods of loess accumulation and soil formation. The loess sequence was correlated with Richmond's Rocky Mountain glacial chronology. At least five major catastrophic flood events occurred in the general vicinity of the channeled scabland. The earliest episode occurred prior to the extensive deposition of the Palouse formation. The last major episode of flooding occurred between about 18,000 and 13,000 years ago. It probably consisted of two outbursts from glacial Lake Missoula.

  12. Mutagenic activity of quaternary ammonium salt derivatives of carbohydrates.

    PubMed

    Dmochowska, Barbara; Sikora, Karol; Woziwodzka, Anna; Piosik, Jacek; Podgórska, Beata

    2016-01-01

    This paper presents a study on a series of quaternary ammonium salt (QAS) derivatives of glucopyranosides with an elongated hydrophobic hydrocarbon chain. The new N-[6-(β-D-glucopyranosyloxy)hexyl]ammonium bromides and their O-acetyl derivatives were analyzed via (1)H and (13)C NMR spectroscopy. The mutagenic activity of the newly synthesized QAS was investigated using two different techniques: The Vibrio harveyi luminescence assay and the Ames test. The obtained results support previous findings contesting QAS safety and indicate that QAS, specifically pyridinium derivatives, might be mutagenic. PMID:27559394

  13. Spatial Response of Mammals to Late Quaternary Environmental Fluctuations

    PubMed

    Graham; Lundelius; Graham; Schroeder; Toomey; Anderson; Barnosky; Burns; Churcher; Grayson; Guthrie; Harington; Jefferson; Martin; McDonald; Morlan; Semken; Webb; Werdelin; Wilson

    1996-06-14

    Analyses of fossil mammal faunas from 2945 localities in the United States demonstrate that the geographic ranges of individual species shifted at different times, in different directions, and at different rates in response to late Quaternary environmental fluctuations. The geographic pattern of faunal provinces was similar for the late Pleistocene and late Holocene, but differing environmental gradients resulted in dissimilar species composition for these biogeographic regions. Modern community patterns emerged only in the last few thousand years, and many late Pleistocene communities do not have modern analogs. Faunal heterogeneity was greater in the late Pleistocene.

  14. Charophytes as lacustrine biomarkers during the quaternary in North Africa

    NASA Astrophysics Data System (ADS)

    Soulié-Märsche, I.

    The use of charophytes as biomarkers is discussed with emphasis on the differences in study methods for cosmopolitan and ecotype species. A first extensive inventory of Quaternary deposits of charophytes in Africa north of the equator comprising 18 sites from Senegal to the Sudan is drawn up with data on spatial and temporal distribution. The existence of relatively deep cold lakes in the Holocene is shown by the frequent presence of specimens of cold flora no longer present in Africa today. All the original data show the complementary nature of the study of fossil Charophyta for the multidisciplinary reconstitution of palaeoenvironments.

  15. Novel quaternary ammonium salts derived from triglycerides and their application in skin and hair products.

    PubMed

    Baydar, A; Johnston, R

    1991-08-01

    Synopsis An investigation has been carried out into the synthesis of quaternary ammonium salts of triglycerides. The aim of this work was to produce such compounds without breaking the triglyceride skeleton. The reaction of chloracetyl chloride with the triglyceride of ricinoleic acid which is the major constituent (88-90%) of castor oil gave an intermediate derivative with pendant chloro groups. Quaternization with stearyl dimethylamine gave a 98% yield of a quaternary ammonium salt containing three quaternary groups per molecule. This reaction sequence overcame the steric hindrance problems encountered in unsuccessful attempts to quaternize halogen groups attached directly to the main chain. Using the same procedure, a quaternary salt was prepared from castor oil. In skin care studies this quaternary was used at a low level in a moisturizing lotion. Subjective assessment of the ease of application of the test lotion versus control was significantly in favour of the test. Viscoelastic measurements of the skin were made using two techniques before and after application of the lotion. Both showed an advantage to the test lotion. No difference between the test and control lotions was found when sebum levels and transepidermal water loss measurements were measured. A C-12 quaternary synthesized from dimethyl-dodecylamine exhibited antimicrobial activity. An aqueous dispersion of the C-18 quaternary when applied to bleached hair in order to improve combing, gave excellent results showing superiority to four other commercially available quaternary ammonium salts.

  16. 40 CFR 721.10342 - Quaternary ammonium compounds, fatty alkyl dialkyl hydroxide (generic).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... alkyl dialkyl hydroxide (generic). 721.10342 Section 721.10342 Protection of Environment ENVIRONMENTAL... Significant New Uses for Specific Chemical Substances § 721.10342 Quaternary ammonium compounds, fatty alkyl... chemical substance identified generically as quaternary ammonium compounds, fatty alkyl dialkyl...

  17. 40 CFR 721.10342 - Quaternary ammonium compounds, fatty alkyl dialkyl hydroxide (generic).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... alkyl dialkyl hydroxide (generic). 721.10342 Section 721.10342 Protection of Environment ENVIRONMENTAL... Significant New Uses for Specific Chemical Substances § 721.10342 Quaternary ammonium compounds, fatty alkyl... chemical substance identified generically as quaternary ammonium compounds, fatty alkyl dialkyl...

  18. 40 CFR 721.10342 - Quaternary ammonium compounds, fatty alkyl dialkyl hydroxide (generic).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... alkyl dialkyl hydroxide (generic). 721.10342 Section 721.10342 Protection of Environment ENVIRONMENTAL... Significant New Uses for Specific Chemical Substances § 721.10342 Quaternary ammonium compounds, fatty alkyl... chemical substance identified generically as quaternary ammonium compounds, fatty alkyl dialkyl...

  19. Recent Progress on the Stereoselective Synthesis of Cyclic Quaternary α-Amino Acids

    PubMed Central

    Cativiela, Carlos; Ordóñez, Mario

    2010-01-01

    The most recent papers describing the stereoselective synthesis of cyclic quaternary α-amino acids are collected in this review. The diverse synthetic approaches are classified according to the size of the ring and taking into account the bond that is formed to complete the quaternary skeleton. PMID:20300486

  20. Synthesis of main-chain chiral quaternary ammonium polymers for asymmetric catalysis using quaternization polymerization.

    PubMed

    Haraguchi, Naoki; Ahamed, Parbhej; Parvez, Md Masud; Itsuno, Shinichi

    2012-01-01

    Main-chain chiral quaternary ammonium polymers were successfully synthesized by the quaternization polymerization of cinchonidine dimer with dihalides. The polymerization occurred smoothly under optimized conditions to give novel type of main-chain chiral quaternary ammonium polymers. The catalytic activity of the polymeric chiral organocatalysts was investigated on the asymmetric benzylation of N-(diphenylmethylidene)glycine tert-butyl ester.

  1. Quaternary extensional and compressional tectonics revealed from Quaternary landforms along Kosi River valley, outer Kumaun Lesser Himalaya, Uttarakhand

    NASA Astrophysics Data System (ADS)

    Luirei, Khayingshing; Bhakuni, S. S.; Kothyari, Girish Ch.; Tripathi, Kavita; Pant, P. D.

    2016-04-01

    A portion of the Kosi River in the outer Kumaun Lesser Himalaya is characterized by wide river course situated south of the Ramgarh Thrust, where huge thickness (~200 m) of the landslide deposits and two to three levels of unpaired fan terraces are present. Brittle normal faults, suggesting extensional tectonics, are recognized in the Quaternary deposits and bedrocks as further supported by surface morphology. Trending E-W, these faults measure from 3 to 5 km in length and are traced as discontinuous linear mini-horst and fault scarps (sackungen) exposed due to cutting across by streams. Active normal faults have displaced the coarsely laminated debris fan deposits at two sites located 550 m apart. At one of the sites, the faults look like bookshelf faulting with the maximum displacement of ~2 m and rotation of the Quaternary boulders along the fault plane is observed. At another site, the maximum displacement measures about 0.60 cm. Thick mud units deposited due to blocking of the streams by landslides are observed within and above the fan deposit. Landslide debris fans and terrace landforms are widely developed; the highest level of fan is observed ~1240 m above mean sea level. At some places, the reworking of the debris fans by streams is characterized by thick laminated sand body. Along the South Almora Thrust and Ramgarh Thrust zones, the valleys are narrow and V-shaped where Quaternary deposits are sparse due to relatively rapid uplift across these thrusts. Along the South Almora Thrust zone, three to four levels of fluvial terraces are observed and have been incised by river exposing the bedrocks due to recent movement along the RT and SAT. Abandoned channel, tilted mud deposits, incised meandering, deep-cut V-shaped valleys and strath terraces indicate rapid uplift of the area. Thick mud sequences in the Quaternary columns indicate damming of streams. A ~10-km-long north-south trending transverse Garampani Fault has offset the Ramgarh Thrust producing

  2. Global warming: Perspectives from the Late Quaternary paleomammal record

    SciTech Connect

    Graham, R.W. )

    1993-03-01

    Global warming at the end of the Pleistocene caused significant environmental changes that directly and indirectly effected biotic communities. The biotic response to this global warming event can provide insights into the processes that might be anticipated for future climatic changes. The megafauna extinction may have been the most dramatic alteration of mammalian communities at the end of the Pleistocene. Late Quaternary warming also altered regional diversity patterns for some small mammal guilds without extinction. Reductions in body size for both small and large mammal species were also consequences of these environmental fluctuations. Geographic shifts in the distributions of individual mammal species resulted in changes in species composition of mammalian communities. The individualistic response of biota to environmental fluctuations define some boundary conditions for modeling communities. Understanding these boundary conditions is mandatory in planning for the preservation of biodiversity in the future. Finally, it is essential to determine how global warming will alter seasonal patterns because it is apparent from the paleobiological record that not all Quaternary warming events have been the same.

  3. Latest Quaternary stratigraphic framework of the Mississippi River delta region

    USGS Publications Warehouse

    Kulp, Mark; Howell, Paul; Adiau, Sandra; Penland, Shea; Kindinger, Jack; Williams, S. Jeffress

    2002-01-01

    Previous researchers separated the uppermost Quaternary stratigraphy of the Mississippi River delta region into two major lithofacies. The stratigraphically lower of these, "substratum," primarily consists of coarse-grained sediment deposited within lowstand-incised stream valleys. Relatively finer-grained "topstratum" overlies substratum; above interfluves, topstratum directly overlies weathered late Pleistocene sediments. However, the onshore to offshore distribution and architecture of these lithofacies was not well constrained. This study integrates published and unpublished lithostratigraphic data with high-resolution seismic profiles from the continental shelf to aid in mapping the regional distribution of major substratum deposits and thickness of topstratum sediments. A transgressive sand sheet commonly marks the base of the topstratum deposits, providing a stratigraphic marker to aid in regional lithostratigraphic correlations. Radiocarbondated deposits and boreholes tied to oxygen isotope chronologies provide chronostratigraphic control. Excellent correlation between these multiple datasets has been found to exist, enabling construction of regional isopachous and structural elevation maps and cross sections detailing elements of the Late Quaternary stratigraphy.

  4. Unexpected primitive rodents in the Quaternary of Argentina

    NASA Astrophysics Data System (ADS)

    Vucetich, María G.; Vieytes, Emma C.; Verzi, Diego H.; Noriega, Jorge I.; Tonni, Eduardo P.

    2005-10-01

    This article describes the first fossils recorded in the Hernandarias Formation (Pleistocene) in Entre Ríos province (eastern Argentina). They are represented by three teeth assigned to the caviomorph rodents (Rodentia, Mammalia) Aenigmys diamantensis gen. et sp. nov. and Eumysops. To establish the phylogenetic affinities of the two most enigmatic teeth, their enamel microstructure was studied. Aenigmys diamantensis is considered the most primitive taxon of a clade formed by Dinomyidae-Neoepiblemidae-Heptaxodontidae. Evidence of the close relationships among these families also is presented herein. The new fossils reinforce previous hypotheses about the survival of primitive Brazilian taxa after their extinction in the Pampas and Patagonia of southern South America. They also show that the diversity of caviomorph rodents during the Quaternary was greater than supposed and that an important Quaternary extinction, not previously detected, affected several lineages. With the available evidence, it is not possible to determine if these rodents indicate a warm pulse or a particular biogeographic situation in Entre Ríos.

  5. Modeling of alkyl quaternary ammonium cations intercalated into montmorillonite lattice

    SciTech Connect

    Daoudi, El Mehdi; Boughaleb, Yahia; El Gaini, Layla; Meghea, Irina; Bakasse, Mina

    2013-05-15

    Highlights: ► The modification of montmorillonites by three surfactants increases the basal spacing. ► The model proposed show a bilayer conformation for the surfactant ODTMA. ► The DODMA and TOMA surfactants adopt a paraffin type arrangement. ► Behavior of surfactants in interlayer space was confirmed by TGA and ATR analysis. - Abstract: The objective of this work was to study the conformation of the quaternary ammonium cations viz., octadecyl trimethyl ammonium (ODTMA), dioctadecyl dimethyl ammonium (DMDOA) and trioctadecyl methyl ammonium (TOMA) intercalated within montmorillonite. The modified montmorillonite was characterized by X-ray diffraction in small angle (SAXS), thermal analysis (TGA) and infrared spectroscopy of attenuated total reflection (ATR). The modification of organophilic montmorillonites by the three surfactants ODTMA, DMDOA and TOMA increases the basal spacing from their respective intercalated distances of 1.9 nm, 2.6 nm and 3.4 nm respectively. The increase in the spacing due to the basic organic modification was confirmed by the results of thermal analysis (TGA) and infrared spectroscopy (ATR), and also supported by theoretical calculations of longitudinal and transversal chain sizes of these alkyl quaternary ammonium cations.

  6. Distribution and metabolism of quaternary amines in salt marshes

    NASA Technical Reports Server (NTRS)

    King, Gary M.

    1985-01-01

    Quaternary amines such as glycine betaine (GBT) are common osmotically active solutes in much of the marine biota. GBT is accumulated by various bacteria, algae, higher plants, invertebrates, and vertebrates in response to salinity or water stresses; in some species, GBT occurs at tens to hundreds of millimolar concentrations and can account for a significant fraction of total nitrogen. Initial studies suggest that GBT is readily converted to two potential methane precursors, trimethylamine (TMA) and acetate, in anoxic sediments. TMA is apparently the most important methane precursor in surface sediments containing sulfate reducing bacteria. In salt marshes, the bulk of the methane formed may be due to the metabolism of TMA rather than other substrates. Current research is focussed on testing this hypothesis and on determining the role of quaternary amino osmoregulatory solutes in methane fluxes from marine environments. Preliminary studies have dealt with several problems: (1) determination of GBT concentrations in the dominant flora and fauna of salt marshes; (2) synthesis of radiolabelled GBT for metabolic studies; and (3) determination of fates of BGT in marine sediments using radiotracers. Both GC and HPLC techniques have been used to assay GBT concentrations in plant and animal tissues. S. alterniflora is probably the only significant source of GBT (and indirectly of methane) since the biomass and distribution of most other species is limited. Current estimates suggest that S. alterniflora GBT could account for most of the methane efflux from salt marshes.

  7. Late Quaternary terrestrial vertebrate coprolites from New Zealand

    NASA Astrophysics Data System (ADS)

    Wood, Jamie R.; Wilmshurst, Janet M.

    2014-08-01

    Over the past decade, concerted efforts to find and study Late Quaternary terrestrial vertebrate coprolites in New Zealand have revealed new insights into the diets and ecologies of New Zealand's prehistoric birds. Here, we provide a broader review of the coprolites found in natural (non-archaeological) Late Quaternary deposits from New Zealand. We summarise the morphological diversity of the coprolites, and discuss the taphonomy of the sites in which they are found. Since the 1870s more than 2000 coprolites have been discovered from 30 localities, all restricted to the South Island. The distribution of coprolite localities appears to reflect the presence of geological and climatic factors that enhance the potential for coprolite preservation; coprolites require dry conditions for preservation, and have been found on the ground surface within drafting cave entrances and at shallow (<300 mm) depths beneath rock overhangs with a northerly aspect. We classify the coprolites into eleven morphotypes, each of which may represent a range of different bird and/or reptile species. A review of genetically identified specimens shows that coprolites of different bird species overlap in size and morphology, reinforcing the need for identifications to be based on ancient DNA analysis.

  8. Quaternary climate - Terrestrial Biosphere Interaction: amplifying or stabilizing?

    NASA Astrophysics Data System (ADS)

    Claussen, Martin

    2016-04-01

    According to the Gaia hypothesis, interaction between climate and biological processes tend to homeostatically maintain, on a global scale, conditions favourable for life. Does the idea of homeostatic interaction between terrestrial biosphere and climate hold for the Quaternary glacial - interglacial changes? Interpretation of palaeoclimate and palaeobotanic evidence by using climate and Earth system models yields an interesting picture. The synergy between the sea-ice albedo - climate feedback and the taiga-tundra - climate feedback is suggested to amplify the orbitally forced climatic precession. This effect seems to be strong at regional scale, but small at global scale. Various simulations indicate that biogeophysical processes amplify the difference of some 4 to 6 K in global mean temperature between glacial and interglacial climate by some 10 percent. The combined effect of biogeophysical and biogeochemical processes, i.e. processes with involve carbon stored in biomass and soil, is less clear. Theoretical studies suggest that in pre-industrial, interglacial climate, a reduction in boreal and extratropical forests tend to cool the climate and a reduction in tropical forest, to warm the climate. Recent estimates in changes in organic carbon stored under ice sheets and in permafrost point at the possibility that the sum of all terrestrial biogeochemical processes might almost "carbon neutral" to the climate system. If corroborated, this observation would favour the assumption of a dominance of biogeophysical processes amplifying orbitally forced Quaternary climate variations.

  9. European quaternary refugia: a factor in large carnivore extinction?

    NASA Astrophysics Data System (ADS)

    O'Regan, Hannah J.; Turner, Alan; Wilkinson, David M.

    2002-12-01

    The extinction of large carnivores in Europe during the Quaternary is reviewed and the potential role of glacial refugia in these extinctions is investigated using the VORTEX model for population viability analysis. A model was built for a medium sized big cat similar to the extinct Panthera gombaszoegensis utilising life history data from the modern jaguar Panthera onca. This approach highlighted the potential importance of glacial refugia in the extinction process. Even model refugia the size of the Italian peninsula did not guarantee persistence of a population over a 1000 yr time span, illustrating the role of chance in survival in such a refugium. An area the size of the largest Mediterranean island was unable to support a big cat population for a period of 1000 yr. The models also demonstrated the importance of inbreeding as a mechanism for extinction in refugia. It is suggested that repeated genetic bottlenecks during successive glaciations would tend to remove lethal recessive alleles from the population, increasing the probability of survival in refugia in subsequent glaciations. The history of extinction of large carnivores in the European Quaternary is interpreted in the light of these results.

  10. Environmental aspects of surface-active quaternary ammonium compounds

    SciTech Connect

    Boethling, R.S.

    1994-12-31

    Cationic surfactants first gained prominence more than 50 years ago, after Domagk`s discovery that the biocidal properties of quaternary ammonium compounds were greatly enhanced by the presence of a long alkyl chain. Present-day applications include fabric softeners, biocides, textile dye leveling agents, oil fields chemicals and asphalt additives, to name only a few. US consumption was estimated at 190,000 metric tons in 1987, most of which was sewered. Cationics thus represent a major class of potential environmental contaminants. As a class they sorb strongly and rapidly to solids in sewage and the aquatic environment. Most major categories of cationics have been shown to undergo extensive aerobic biodegradation in low-biomass test systems, when tested at environmentally relevant concentrations. But anaerobic biodegradation, although not well studied, appears to be slow, and the lower degradability of dialkyl quaternaries in general is now leading to their replacement by analogs containing ester or amide linkages to enhance biodegradation. Cationics are also toxic to aquatic organisms, including fish, invertebrates and algae. Acute toxicity is fairly well characterized, but data on chronic toxicity are more limited and support concern concentrations in the ug/L range. In the aquatic environment sorption to sediment and dissolved organic carbon may substantially reduce acute toxicity, but bioavailability in the gut warrants further study.

  11. Late quaternary environments, Denali National Park and Preserve, Alaska

    USGS Publications Warehouse

    Elias, S.A.; Short, S.K.; Waythomas, C.F.

    1996-01-01

    Late Quaternary pollen, plant macrofossils, and insect fossils were studied from sites along three rivers in the foothills north of the Alaska Range in Denali National Park and Preserve. The aim was to carry out a reconaissance of late Quaternary organic sediments in the region, emphasizing the mid-Wisconsin, or Boutellier interstadial interval. Samples of probable early- to mid-Boutellier age (ca. 60 000 to 40 000 B.P.) from Unit 2 at the Toklat High Bluffs site indicate open boreal woodland with dense alder shrub vegetation. Organic Unit 1 at the Foraker River Slump site indicates open taiga with shrubs of probable Boutellier age. Fossil evidence from the youngest horizon in this unit indicates graminoid tundra environments, marking the transition from interstadial to late Wisconsin glacial environments. Early Holocene samples from the Foraker exposures suggest birch shrub tundra; coniferous forest apparently became established only alter 6500 B.P. Local variations in forest composition at the Foraker and Sushana sites were probably the result of disturbances, such as fire.

  12. Neogene-Quaternary eustasy and collision tectonism in western Taiwan

    SciTech Connect

    Teng, L.S. )

    1991-03-01

    Taiwan is an active orogen formed by the collision between the Luzon arc and the Asian continent. Thick late Cenozoic coastal to shallow marine deposits exposed in the western foothills of western Taiwan preserved the sedimentary record of both tectonic and eustatic influences. Relating to the arc-continent collision, the Oligocene-Miocene deposits can be regarded as the pre-collisional continental margin sequence and the Pliocene-Quaternary deposits as the post-collisional foreland basin sequence. Geohistory analysis shows that the rates of sediment accumulation and basin subsidence remained low during the Miocene but increased dramatically during the Pliocene-Quaternary, reflecting the effects of exacerbated loading and unroofing of the growing orogen. In spite of the intense tectonic influence, facies variations in both the continental margin sequence and the foreland basin sequence are chronostratigraphically consistent with global eustatic fluctuations. It appears that eustatic fluctuations were able to leave a distinct signature in stratigraphic records regardless of the effects of collision tectonics.

  13. [QUATERNARY PREVENTION: AN ATTEMPT TO AVOID THE EXCESSES OF MEDICINE].

    PubMed

    Noble, María

    2015-01-01

    Seduced by technology, biometrics, practical guidelines and the use of medication, medicine has been driven away from the subject of its care. Quaternary prevention is, among other voices around the world, trying to denounce the consequent excesses of medical practice given by this situation. There are visible excesses, such as the long list of studies being performed on patients without indication, and others, much more subtle, as excessive prevention and the continuous and progressive medicalization of life itself that are rooted in our culture and demanded by a society that requests certainty at almost any cost. Quaternary prevention proposes a series of actions leaning towards avoiding and diminishing the damage produced by health care activities, in order to protect the subject of overdiagnosis and overtreatment; offering also ethical and viable alternatives in which the balance of risks and benefits (based on the best evidences) respects the autonomy of the subject by properly informing and allowing him to decide among the best options he has; altogether in a process that contemplates a rational and equitable use of resources. In order to achieve this, reliable sources of information and a medical education not dependent on industries related to technology or pharmaceuticals, are vital; in conjuction with a medicine that restablishes the subject as its main and central interest. PMID:26966752

  14. Historical distribution of Sundaland's Dipterocarp rainforests at Quaternary glacial maxima.

    PubMed

    Raes, Niels; Cannon, Charles H; Hijmans, Robert J; Piessens, Thomas; Saw, Leng Guan; van Welzen, Peter C; Slik, J W Ferry

    2014-11-25

    The extent of Dipterocarp rainforests on the emergent Sundaland landmass in Southeast Asia during Quaternary glaciations remains a key question. A better understanding of the biogeographic history of Sundaland could help explain current patterns of biodiversity and support the development of effective forest conservation strategies. Dipterocarpaceae trees dominate the rainforests of Sundaland, and their distributions serve as a proxy for rainforest extent. We used species distribution models (SDMs) of 317 Dipterocarp species to estimate the geographic extent of appropriate climatic conditions for rainforest on Sundaland at the last glacial maximum (LGM). The SDMs suggest that the climate of central Sundaland at the LGM was suitable to sustain Dipterocarp rainforest, and that the presence of a previously suggested transequatorial savannah corridor at that time is unlikely. Our findings are supported by palynologic evidence, dynamic vegetation models, extant mammal and termite communities, vascular plant fatty acid stable isotopic compositions, and stable carbon isotopic compositions of cave guano profiles. Although Dipterocarp species richness was generally lower at the LGM, areas of high species richness were mostly found off the current islands and on the emergent Sunda Shelf, indicating substantial species migration and mixing during the transitions between the Quaternary glacial maxima and warm periods such as the present.

  15. Ecostratigraphic datums and sequence stratigraphy: Application to the marine Quaternary

    SciTech Connect

    Martin, R.E. ); Neff, E. ); Johnson, G.W. ); Krantz, D. )

    1991-03-01

    The marine Quaternary is characterized by few evolutionary appearances and extinctions of planktonic foraminifera. Because climatic fluctuations are a fundamental characteristic of Pleistocene, however, better stratigraphic resolution of the marine Quaternary can be gained by the establishment of biozones based on climatically controlled foraminiferal assemblages. Utilizing relative abundances of the warm-water Globorotalia menardii complex and temperature-water G. inflata, supplemented by left- and right-coiling varieties of G. truncatulinoides, the authors have subdivided the prezone-W Pleistocene of the tropical Atlantic (Core V16-205), Caribbean Sea (DSDP Core 502B), and northeast Gulf of Mexico (ODP Core 625B, Eureka Core E67-135) into 17 subzones, each with an average duration of {approximately}100,000 yrs. The subzones appear to reflect water mass shifts and disjunct species distributions resulting from expansion and contraction of northern hemisphere ice sheets. Hence, subzonal boundaries should also reflect change in eustatic sea level and sequence boundaries. Indeed, graphic correlation of the subzones, along with biostratigraphic markers and paleomagnetic and oxygen isotope datums, reveals changes in sediment accumulation rate (especially on the continental slope) and missing section, as well as intervals of deformation (core breaks) that affect the occurrence of subzonal boundaries and biostratigraphic markers.

  16. Late Quaternary geomorphology and soils in Crater Flat, Yucca mountain area, southern Nevada

    SciTech Connect

    Peterson, F.F.; Bell, J.W.; Ramelli, A.R.; Dorn, R.I.; Ku, T.L.

    1995-04-01

    Crater Flat is an alluvium-filled structural basin on the west side of Yucca Mountain, Nevada, which is under consideration for a high-level nuclear waste repository. North-trending, late Quaternary faults offset alluvium in Crater Flat both along the canyons of the western flanks of Yucca Mountain and out on the piedmont slope. We believe the initial lack of young offsets at Yucca Mountain was in part due to unrecognized late Quaternary stratigraphy. We hypothesize that alluviation in the Yucca Mountain region was more active during the late Quaternary than previously thought. Several techniques were tried to test this hypothesis. Results are compared with previous soils and surface-exposure dating studies, and correlated to stratigraphy of other late Quaternary units in the southern Nevada, Death Valley, and Mojave Desert areas, and provide new stratigraphic data relevant to understanding climatic-alluvial processes in the Basin and Range Province during the late Quaternary. 76 refs., 7 figs., 6 tabs.

  17. Senior Centers

    MedlinePlus Videos and Cool Tools

    ... something many older adults would like to do as long as they can. Senior centers, adult day care, transportation, ... adults who live independently can go to find a variety of social and recreational activities. [Karen Albers] ...

  18. Coastal Center

    NASA Astrophysics Data System (ADS)

    The U.S. Geological Survey dedicated its new Center for Coastal Geology June 12 at the University of South Florida in St. Petersburg. Robert Halley leads the staff of nine USGS scientists studying coastal erosion and pollution and underwater mineral resources in cooperation with the university's Marine Science Department. Current research is on erosion along Lake Michigan and the Gulf Coast of Louisiana. The number of USGS scientists at the center should increase to 30 over five years.

  19. Assessing biomarker syngeneity using branched alkanes with quaternary carbon (BAQCs) and other plastic contaminants

    NASA Astrophysics Data System (ADS)

    Brocks, Jochen J.; Grosjean, Emmanuelle; Logan, Graham A.

    2008-02-01

    Biomarker molecules are valuable for the elucidation of ancient microbial ecosystems and the characterization of petroleum source rocks. For such studies, acquisition of reliable hydrocarbon data and proof of their syngeneity are essential. However, contamination of geological samples with anthropogenic petroleum products during drilling, storage and sampling can be particularly problematic because these hydrocarbons may over-print an original indigenous biomarker profile. To evaluate the extent of contamination of drill core and outcrop material, we studied the distribution of hydrocarbons in 26 rocks from different locations in the world. All rocks had petroleum products on their exterior surfaces. Twenty-two samples also contained surficial hydrocarbons derived from polyethylene plastic, including branched alkanes with quaternary carbon centers (BAQCs) and alkylcyclopentanes with pronounced even-over-odd carbon number preference. Using three examples from the Paleoproterozoic Tawallah and McArthur Groups in northern Australia, we show how indigenous biomarkers can be recognized by comparing hydrocarbon distributions between exterior rock surfaces and the rock interior, and how infiltration of allochthonous hydrocarbons can be assessed through the spatial distribution of characteristic polyethylene derived hydrocarbons in the rock. The methods outlined in this paper give confidence in the interpretation of biomarkers in particularly sensitive applications such as the first occurrences of certain organisms in the geological record and the provenance of organic matter in meteorites.

  20. Development of Ternary and Quaternary Catalysts for the Electrooxidation of Glycerol

    PubMed Central

    Artem, L. M.; Santos, D. M.; De Andrade, A. R.; Kokoh, K. B.; Ribeiro, J.

    2012-01-01

    This work consisted in the preparation of platinum-based catalysts supported on carbon (Vulcan XC-72) and investigation of their physicochemical and electrochemical properties. Catalysts of the C/Pt-Ni-Sn-Me (Me = Ru or Ir) type were prepared by the Pechini method at temperature of 350°C. Four different compositions were homemade: C/Pt60Sn10Ni30, C/Pt60Sn10Ni20Ru10, C/Pt60Sn10Ni10Ru20, and C/Pt60Sn10Ni10Ir20. These catalysts were electrochemically and physically characterized by cyclic voltammetry (CV), chronoamperometry (CA) in the presence of glycerol 1.0 mol dm−3, X-ray diffraction (XRD), and high-resolution transmission electron microscopy (HRTEM). XRD results showed the main peaks of face-centered cubic Pt. The particle sizes obtained from XRD and HRTEM experiments were close to values ranging from 3 to 8.5 nm. The CV results indicate behavior typical of Pt-based catalysts in acid medium. The CV and CA data reveal that quaternary catalysts present the highest current density for the electrooxidation of glycerol. PMID:22623905

  1. Crystal structures and optical properties of new quaternary strontium europium aluminate luminescent nanoribbons

    SciTech Connect

    Li, Xufan; Budai, John D.; Liu, Feng; Chen, Yu-Sheng; Howe, Jane Y.; Sun, Chengjun; Tischler, Jonathan Zachary; Meltzer, Richard; Pan, Zhengwei

    2014-11-12

    We report the synthesis and characterizations of three series of quaternary strontium europium aluminate (Sr-Eu-Al-O; SEAO) luminescent nanoribbons that show blue, green, and yellow luminescence from localized Eu2+ luminescent centers. These three series of SEAO nanoribbons are: blue luminescent, tetragonal Sr1-xEuxAl6O10 (01-xEuxAl2O4 (01-xEuxAl2O4 (0

  2. Quaternary history and contemporary patterns in a currently expanding species

    PubMed Central

    Kerdelhué, Carole; Zane, Lorenzo; Simonato, Mauro; Salvato, Paola; Rousselet, Jérôme; Roques, Alain; Battisti, Andrea

    2009-01-01

    Background Quaternary climatic oscillations had dramatic effects on species evolution. In northern latitudes, populations had to survive the coldest periods in refugial areas and recurrently colonized northern regions during interglacials. Such a history usually results in a loss of genetic diversity. Populations that did not experience glaciations, in contrast, probably maintained most of their ancestral genetic diversity. These characteristics dramatically affected the present-day distribution of genetic diversity and may influence the ability of species to cope with the current global changes. We conducted a range-wide study of mitochondrial genetic diversity in the pine processionary moth (Thaumetopoea pityocampa/T. wilkinsoni complex, Notodontidae), a forest pest occurring around the Mediterranean Basin and in southern Europe. This species is responding to the current climate change by rapid natural range expansion and can also be accidentally transported by humans. Our aim was to assess if Quaternary climatic oscillations had a different effect across the species' range and to determine if genetic footprints of contemporary processes can be identified in areas of recent introduction. Results We identified three main clades that were spatially structured. In most of Europe, the genetic diversity pattern was typical for species that experienced marked glaciation cycles. Except in refugia, European populations were characterized by the occurrence of one main haplotype and by a strong reduction in genetic diversity, which is expected in regions that were rapidly re-colonized when climatic conditions improved. In contrast, all other sub-clades around the Mediterranean Basin occurred in limited parts of the range and were strongly structured in space, as is expected in regions in which the impact of glaciations was limited. In such places, genetic diversity was retained in most populations, and almost all haplotypes were endemic. This pattern was extreme on remote

  3. Copper(II)- and Palladium(II)-Catalyzed Enantioselective Claisen Rearrangement of Allyloxy- and Propargyloxy-Indoles to Quaternary Oxindoles and Spirocyclic Lactones

    PubMed Central

    Cao, Trung; Linton, Elizabeth C.; Deitch, Joshua; Berritt, Simon

    2012-01-01

    In this paper, a strategy to obtain highly enantioselective catalysts for the Claisen rearrangement of allyloxy- and propargyloxy-indoles is outlined. Ultimately, copper BOX and palladium BINAP or PHOX catalysts were discovered as superior in catalyzing Claisen rearrangements of allyloxy- or proparyloxy-substituted indoles to generate oxindoles bearing allyl- or allenyl-substituted quaternary centers. This method proved to be tolerant of a broad range of functional groups. Tandem reactions of the silyl-allene products provide rapid access to a variety of spirocyclic oxindoles in one operation. PMID:23167569

  4. High Resolution Quaternary Seismic Stratigraphy of the New York Bight Continental Shelf

    USGS Publications Warehouse

    Schwab, William C.; Denny, J.F.; Foster, D.S.; Lotto, L.L.; Allison, M.A.; Uchupi, E.; Swift, B.A.; Danforth, W.W.; Thieler, E.R.; Butman, Bradford

    2003-01-01

    A principal focus for the U.S. Geological Survey (USGS) Coastal and Marine Geology Program (marine.usgs.gov) is regional reconnaissance mapping of inner-continental shelf areas, with initial emphasis on heavily used areas of the sea floor near major population centers. The objectives are to develop a detailed regional synthesis of the sea-floor geology in order to provide information for a wide range of management decisions and to form a basis for further investigations of marine geological processes. In 1995, the USGS, in cooperation with the U.S. Army Corps of Engineers (USACOE), New York District, began to generate reconnaissance maps of the continental shelf seaward of the New York - New Jersey metropolitan area. This mapping encompassed the New York Bight inner-continental shelf, one of the most heavily trafficked and exploited coastal regions in the United States. Contiguous areas of the Hudson Shelf Valley, the largest physiographic feature on this segment of the continental shelf, also were mapped as part of a USGS study of contaminated sediments (Buchholtz ten Brink and others, 1994; 1996). The goal of the reconnaissance mapping was to provide a regional synthesis of the sea-floor geology in the New York Bight area, including: (a) a description of sea-floor morphology; (b) a map of sea-floor sedimentary lithotypes; (c) the geometry and structure of the Cretaceous strata and Quaternary deposits; and (d) the geologic history of the region. Pursuing the course of this mapping effort, we obtained sidescan-sonar images of 100 % of the sea floor in the study area. Initial interpretations of these sidescan data were presented by Schwab and others, (1997a, 1997b, 2000a). High-resolution seismic-reflection profiles collected along each sidescan-sonar line used multiple acoustic sources (e.g., watergun, CHIRP, Geopulse). Multibeam swath-bathymetry data also were obtained for a portion of the study area (Butman and others, 1998;). In this report, we present a series

  5. Expanded record of Quaternary oceanographic change: Amerasian Arctic Ocean

    USGS Publications Warehouse

    Ishman, S.E.; Polyak, L.V.; Poore, R.Z.

    1996-01-01

    Four sediment cores collected from the Northwind and Mendeleyev ridges, Arctic Ocean, from 1089 m to 1909 m water depth, provide an oceanographic record extending back into the Matuyama reversed polarity chron. Benthic foraminiferal analyses show four prominent assemblage zones: Bolivina arctica, Cassidulina teretis, Bulimina aculeata, and Oridorsalis tener from the upper Matuyama reversed polarity chronozone through the Brunhes normal polarity chronozone. These assemblage zones represent depth-dependent benthic foraminiferal biofacies changes associated with oceanographic events that occurred in the Amerasian basin at ??? 780 and 300 ka, and indicate oceanographic influence from the North Atlantic. Recognition of these benthic assemblage zones in Arctic cores from the Alpha Ridge indicates that the benthic foraminiferal zonations in intermediate to deep water (>1000 m) Arctic cores may be more useful than preexisting lithostratigraphic zonations and should provide important information pertaining to the Quaternary paleoceanographic evolution of the Arctic Ocean.

  6. Luminescence studies on nitride quaternary alloys double quantum wells

    NASA Astrophysics Data System (ADS)

    Rodrigues, S. C. P.; dos Santos, O. F. P.; Scolfaro, L. M. R.; Sipahi, G. M.; da Silva, E. F., Jr.

    2008-09-01

    We present theoretical photoluminescence (PL) spectra of undoped and p-doped Al xIn 1- x- yGa yN/Al XIn 1- X- YGa YN double quantum wells (DQWs). The calculations were performed within the k.p method by means of solving a full eight-band Kane Hamiltonian together with the Poisson equation in a plane wave representation, including exchange-correlation effects within the local density approximation. Strain effects due to the lattice mismatch are also taken into account. We show the calculated PL spectra, analyzing the blue and red-shifts in energy as one varies the spike and the well widths, as well as the acceptor doping concentration. We found a transition between a regime of isolated quantum wells and that of interacting DQWs. Since there are few studies of optical properties of quantum wells based on nitride quaternary alloys, the results reported here will provide guidelines for the interpretation of forthcoming experiments.

  7. Control of Quaternary sea-level changes on gas seeps

    NASA Astrophysics Data System (ADS)

    Riboulot, Vincent; Thomas, Yannick; Berné, Serge; Jouet, Gwénaël.; Cattaneo, Antonio

    2014-07-01

    Gas seeping to the seafloor through structures such as pockmarks may contribute significantly to the enrichment of atmospheric greenhouse gases and global warming. Gas seeps in the Gulf of Lions, Western Mediterranean, are cyclical, and pockmark "life" is governed both by sediment accumulation on the continental margin and Quaternary climate changes. Three-dimensional seismic data, correlated to multi-proxy analysis of a deep borehole, have shown that these pockmarks are associated with oblique chimneys. The prograding chimney geometry demonstrates the syn-sedimentary and long-lasting functioning of the gas seeps. Gas chimneys have reworked chronologically constrained stratigraphic units and have functioned episodically, with maximum activity around sea level lowstands. Therefore, we argue that one of the main driving mechanisms responsible for their formation is the variation in hydrostatic pressure driven by relative sea level changes.

  8. Asynchronous extinction of late Quaternary sloths on continents and islands

    PubMed Central

    Steadman, David W.; Martin, Paul S.; MacPhee, Ross D. E.; Jull, A. J. T.; McDonald, H. Gregory; Woods, Charles A.; Iturralde-Vinent, Manuel; Hodgins, Gregory W. L.

    2005-01-01

    Whatever the cause, it is extraordinary that dozens of genera of large mammals became extinct during the late Quaternary throughout the Western Hemisphere, including 90% of the genera of the xenarthran suborder Phyllophaga (sloths). Radiocarbon dates directly on dung, bones, or other tissue of extinct sloths place their “last appearance” datum at ≈11,000 radiocarbon years before present (yr BP) or slightly less in North America, ≈10,500 yr BP in South America, and ≈4,400 yr BP on West Indian islands. This asynchronous situation is not compatible with glacial–interglacial climate change forcing these extinctions, especially given the great elevational, latitudinal, and longitudinal variation of the sloth-bearing continental sites. Instead, the chronology of last appearance of extinct sloths, whether on continents or islands, more closely tracks the first arrival of people. PMID:16085711

  9. Exposure to common quaternary ammonium disinfectants decreases fertility in mice.

    PubMed

    Melin, Vanessa E; Potineni, Haritha; Hunt, Patricia; Griswold, Jodi; Siems, Bill; Werre, Stephen R; Hrubec, Terry C

    2014-12-01

    Quaternary ammonium compounds (QACs) are antimicrobial disinfectants commonly used in commercial and household settings. Extensive use of QACs results in ubiquitous human exposure, yet reproductive toxicity has not been evaluated. Decreased reproductive performance in laboratory mice coincided with the introduction of a disinfectant containing both alkyl dimethyl benzyl ammonium chloride (ADBAC) and didecyl dimethyl ammonium chloride (DDAC). QACs were detected in caging material over a period of several months following cessation of disinfectant use. Breeding pairs exposed for six months to a QAC disinfectant exhibited decreases in fertility and fecundity: increased time to first litter, longer pregnancy intervals, fewer pups per litter and fewer pregnancies. Significant morbidity in near term dams was also observed. In summary, exposure to a common QAC disinfectant mixture significantly impaired reproductive health in mice. This study illustrates the importance of assessing mixture toxicity of commonly used products whose components have only been evaluated individually.

  10. Quaternary geology and ecology of the Greater Yellowstone area

    USGS Publications Warehouse

    Pierce, Kenneth L.; Despain, D.G.; Whitlock, Cathy; Cannon, Kenneth P.; Meyer, Grant A.; Morgan, Lisa; Licciardi, Joseph M.

    2003-01-01

    This field guide focuses on the glacial geology, ecology, paleoecology, caldera unrest, and archeology in Yellowstone and Grand Teton national parks and vicinity (Fig. 1). Some previous field guides of Yellowstone are Locke et al. (1995) for the Yellowstone valley, Fournier et al. (1994) for hydrothermal and volcanic geology of Yellowstone, and Pierce and Good (1992) for the Quaternary of Jackson Hole. Non–technical overviews of Yellowstone and Grand Teton National Parks are Good and Pierce (1996) and Smith and Siegel (2000). Geologic maps are: Grand Teton (Love et al., 1992), and Yellowstone (bedrock and surficial geology (USGS, 1972a; 1972b). Christiansen (2001) extensively describes Yellowstone’s volcanic geology, and Pierce (1979) describes the glacial geology of the northern Yellowstone region. We suggest that you obtain detailed maps.

  11. Asynchronous extinction of late Quaternary sloths on continents and islands.

    PubMed

    Steadman, David W; Martin, Paul S; MacPhee, Ross D E; Jull, A J T; McDonald, H Gregory; Woods, Charles A; Iturralde-Vinent, Manuel; Hodgins, Gregory W L

    2005-08-16

    Whatever the cause, it is extraordinary that dozens of genera of large mammals became extinct during the late Quaternary throughout the Western Hemisphere, including 90% of the genera of the xenarthran suborder Phyllophaga (sloths). Radiocarbon dates directly on dung, bones, or other tissue of extinct sloths place their "last appearance" datum at approximately 11,000 radiocarbon years before present (yr BP) or slightly less in North America, approximately 10,500 yr BP in South America, and approximately 4,400 yr BP on West Indian islands. This asynchronous situation is not compatible with glacial-interglacial climate change forcing these extinctions, especially given the great elevational, latitudinal, and longitudinal variation of the sloth-bearing continental sites. Instead, the chronology of last appearance of extinct sloths, whether on continents or islands, more closely tracks the first arrival of people.

  12. Exposure to common quaternary ammonium disinfectants decreases fertility in mice

    PubMed Central

    Melin, Vanessa E.; Potineni, Haritha; Hunt, Patricia; Griswold, Jodi; Siems, Bill; Werre, Stephen R.; Hrubec, Terry C.

    2014-01-01

    Quaternary ammonium compounds (QACs) are antimicrobial disinfectants commonly used in commercial and household settings. Extensive use of QACs results in ubiquitous human exposure, yet reproductive toxicity has not been evaluated. Decreased reproductive performance in laboratory mice coincided with the introduction of a disinfectant containing both alkyl dimethyl benzyl ammonium chloride (ADBAC) and didecyl dimethyl ammonium chloride (DDAC). QACs were detected in caging material over a period of several months following cessation of disinfectant use. Breeding pairs exposed for six months to a QAC disinfectant exhibited decreases in fertility and fecundity: increased time to first litter, longer pregnancy intervals, fewer pups per litter and fewer pregnancies. Significant morbidity in near term dams was also observed. In summary, exposure to a common QAC disinfectant mixture significantly impaired reproductive health in mice. This study illustrates the importance of assessing mixture toxicity of commonly used products whose components have only been evaluated individually. PMID:25483128

  13. Late Quaternary folding of coral reef terraces, Barbados

    NASA Astrophysics Data System (ADS)

    Taylor, Frederick W.; Mann, Paul

    1991-02-01

    Uplifted late Ouaternary coral reefs on the island of Barbados record folding of the emergent crest of the Lesser Antilles accretionary prism (Barbados Ridge complex) since ca. 1 Ma. Three northeast striking folds are defined by systematic changes in altitudes in the crest of First High Cliff, a mostly constructional reef terrace about 125 ka, and Second High Cliff, a partially erosional reef terrace about 500 ka. The folds have wavelengths of 6 to 8 km and fold axes extend about 10 km. The largest anticline rises to the northeast, where it has been breached by erosion exposing highly deformed Eocene to lower Miocene rocks of the Scotland District. Uplift rates based on heights of the last interglacial First High Cliff range from 0.07 to 0.44 mm/yr. Quaternary folding on Barbados indicates that the crest of the accretionary prism continues to be an active fold belt undergoing northwestsoutheast shortening.

  14. The Use of Quaternary Ammonium to Combat Dental Caries

    PubMed Central

    Ge, Yang; Wang, Suping; Zhou, Xuedong; Wang, Haohao; Xu, Hockin H. K.; Cheng, Lei

    2015-01-01

    Resin composites and adhesives are increasingly popular in dental restorations, but secondary caries is one of the main reasons for restoration failure. Quaternary ammonium monomers (QAMs) have an anti-microbial effect and are widely used in many fields. Since the concept of the immobilized antibacterial effect was put forward, dental restorations containing QAMs have been studied to reduce secondary caries. Previous studies have been struggling to develop novel anti-caries materials which might have triple benefits: good mechanical properties, antibacterial effects and remineralization potentials. Different kinds of QAMs have been proven to be effective in inhibiting the growth and metabolism of biofilms. Combination of QAMs and other nanoparticles in resin composites and adhesives could enhance their anti-caries capability. Therefore, QAMs are promising to show significant impact on the future of restorative and preventive dentistry. PMID:26635932

  15. Quaternary geophysical framework of the northeastern North Carolina coastal system

    USGS Publications Warehouse

    Thieler, E.R.; Foster, D.S.; Mallinson, D.M.; Himmelstoss, E.A.; McNinch, J.E.; List, J.H.; Hammar-Klose, E.S.

    2013-01-01

    The northeastern North Carolina coastal system, from False Cape, Virginia, to Cape Lookout, North Carolina, has been studied by a cooperative research program that mapped the Quaternary geologic framework of the estuaries, barrier islands, and inner continental shelf. This information provides a basis to understand the linkage between geologic framework, physical processes, and coastal evolution at time scales from storm events to millennia. The study area attracts significant tourism to its parks and beaches, contains a number of coastal communities, and supports a local fishing industry, all of which are impacted by coastal change. Knowledge derived from this research program can be used to mitigate hazards and facilitate effective management of this dynamic coastal system.

  16. Dimeric Quaternary Structure of Human Laforin*♦

    PubMed Central

    Sankhala, Rajeshwer S.; Koksal, Adem C.; Ho, Lan; Nitschke, Felix; Minassian, Berge A.; Cingolani, Gino

    2015-01-01

    The phosphatase laforin removes phosphate groups from glycogen during biosynthetic activity. Loss-of-function mutations in the gene encoding laforin is the predominant cause of Lafora disease, a fatal form of progressive myoclonic epilepsy. Here, we used hybrid structural methods to determine the molecular architecture of human laforin. We found that laforin adopts a dimeric quaternary structure, topologically similar to the prototypical dual specificity phosphatase VH1. The interface between the laforin carbohydrate-binding module and the dual specificity phosphatase domain generates an intimate substrate-binding crevice that allows for recognition and dephosphorylation of phosphomonoesters of glucose. We identify novel molecular determinants in the laforin active site that help decipher the mechanism of glucan phosphatase activity. PMID:25538239

  17. Synthesis and Antibacterial Activity of Quaternary Ammonium 4-Deoxypyridoxine Derivatives

    PubMed Central

    Shtyrlin, Nikita V.; Sapozhnikov, Sergey V.; Galiullina, Albina S.; Kayumov, Airat R.; Bondar, Oksana V.; Mirchink, Elena P.; Isakova, Elena B.; Firsov, Alexander A.; Balakin, Konstantin V.

    2016-01-01

    A series of novel quaternary ammonium 4-deoxypyridoxine derivatives was synthesized. Two compounds demonstrated excellent activity against a panel of Gram-positive methicillin-resistant S. aureus strains with MICs in the range of 0.5–2 μg/mL, exceeding the activity of miramistin. At the same time, both compounds were inactive against the Gram-negative E. coli and P. aeruginosa strains. Cytotoxicity studies on human skin fibroblasts and embryonic kidney cells demonstrated that the active compounds possessed similar toxicity with benzalkonium chloride but were slightly more toxic than miramistin. SOS-chromotest in S. typhimurium showed the lack of DNA-damage activity of both compounds; meanwhile, one compound showed some mutagenic potential in the Ames test. The obtained results make the described chemotype a promising starting point for the development of new antibacterial therapies. PMID:27800491

  18. Quaternary incised valleys in southern Brazil coastal zone

    NASA Astrophysics Data System (ADS)

    Weschenfelder, Jair; Baitelli, Ricardo; Corrêa, Iran C. S.; Bortolin, Eduardo C.; dos Santos, Cristiane B.

    2014-11-01

    High-resolution seismic records obtained in the Rio Grande do Sul coastal zone, southern Brazil, revealed that prominent valleys and channels developed in the area before the installation of actual coastal plain. Landwards, the paleoincisions can be linked with the present courses of the main river dissecting the area. Oceanwards, they can be linked with related features previously recognized in the continental shelf and slope by means of seismic and morphostructural studies. Based mainly on seismic, core data and geologic reasoning, it can be inferred that the coastal valleys were incised during forced regression events into the coastal prism deposited during previous sea level highstand events of the Quaternary. Seismic data has revealed paleovalleys up to 10 km wide and, in some places, infilled with up to 40 m thick of sediments. The results indicated two distinct periods of cut-and-fill events in the Patos Lagoon area. The filling of the younger incision system is mainly Holocene and its onset is related to the last main regressive event of the Pleistocene, when the sea level fell about 130 m below the actual position. The older incision and filling event is related to the previous regressive-transgressive events of the Middle and Late Pleistocene. The fluvial discharge fed delta systems on the shelf edge during the sea level lowstands. The subsequent transgressions drowned the incised drainage, infilling it and closing the inlets formerly connecting the coastal river to the ocean. The incised features may have played a significant role on the basin-margin architecture, facies distribution and accommodation space during the multitude of up and down sea level events of the Quaternary.

  19. Book Review: The history of the Quaternary Research Association

    NASA Astrophysics Data System (ADS)

    Bowen, D. Q.

    2016-06-01

    This is a book that should be in the library of every member of the QRA as well as their institutions. This volume is a celebration of 50 years of the Quaternary Studies Field Group (1964), which was renamed the Quaternary Research Association (QRA) in 1969. What follows is a combination of a review with some further information based on the recollection of someone who was there. In examining the origins of the QSFG due credit is paid to Richard Hey and Richard West, but an inexplicable omission is the earlier discussion between Hey, Allan Straw and others during the field meeting of the Yorkshire Geological Society in September 1962 (Worsley, 2014). It is said that history is always written by the victors, or in modern parlance by those who write the minutes! But, in the writing of history there are only degrees of unsuccess. In Chapter 2 John Catt comments on the less than perfect early archival records of the QRA. So it is to his credit that 50 years of archival material has been diligently sifted and edited. In this he was assisted by memories of some named QRA members who are thanked. Wider consultation may have filled some of the gaps. At earlier meetings it was always a pleasure to greet long retired colleagues, such as Archie Lamont at the Carlops glacial drainage system when being demonstrated by Brian Sissons in 1966, or Tony Farringdon at Ballycotton Bay in 1968, or Hallam Movius in 1971 at a London discussion meeting. Similarly, who can forget the field meeting at Canterbury in 1967 when Alec Skempton demonstrated the Sevenoaks by-pass late-glacial slope failures, and John Hutchinson's use of Pomatias elegans for dating the Folkestone Warren landslips? Jan Mangerud's first QRA meeting on the Isle of Man (1971) was notable for his prescient recognition of glaciomarine deposits.

  20. Isotopic characteristics of mantle sources for Quaternary continental alkaline magmas in the northern Canadian Cordillera

    NASA Astrophysics Data System (ADS)

    Carignan, Jean; Ludden, John; Francis, Don

    1994-12-01

    Three mantle compositions are identified as potential source end members for Quaternary to recent alkaline volcanic rocks from Fort Selkirk, Llangorse-Hirschfeld, Alligator Lake and Mt. Edziza in the northern Canadian Cordillera. These are: (1) an amphibole-rich source, characterized by unradiogenic Sr, Nd and Pb, from which the olivine nephelinite lavas formed, (2) the continental lithospheric mantle which is characterised by high Pb-207/Pb-204 and appears to be involved in the formation of the alkali olivine basalts of Fort Selkirk, and (3) a mantle with radiogenic Pb and unradiogenic Sr (HIMU-type) represented by lavas from Mt. Edziza. The Mt. Edziza volcano is the largest of the volcanic centres in the region, and is considered to reflect melting of sublithospheric mantle of HIMU composition below central British Columbia. Incipient melting of amphibole-veined subcontinental mantle lithosphere resulted from plume upwelling and/or transtensional pressure release and produced the small nephelinite to olivine basalt centres of the northern Cordilleran Province. The source of the nephelinite magmas is slightly more radiogenic than present-day Pacific Mid-Ocean ridge basalts (MORB), and is best represented by the most depleted component of the Aleutian magmas. This suggests enrichment of the subcontinental lithosphere in the northern Cordillera by melts of this isotopic composition during Cretaceous subduction. The Alligator Lake complex is anomalous and charaterized by the most radiogenic lavas. Despite the presence of crustal xenoliths there is no clear geochemical signature for crustal contamination and, in contrast to the other volcanic centers which were erupted through the Intermontain Belt, the lavas of this center may have been derived from a highly radiogenic lithospheric mantle beneath the Coast Plutonic complex.

  1. Synthetic Strategies toward Natural Products Containing Contiguous Stereogenic Quaternary Carbon Atoms.

    PubMed

    Büschleb, Martin; Dorich, Stéphane; Hanessian, Stephen; Tao, Daniel; Schenthal, Kyle B; Overman, Larry E

    2016-03-18

    Strategies for the total synthesis of complex natural products that contain two or more contiguous stereogenic quaternary carbon atoms in their intricate structures are reviewed with 12 representative examples. Emphasis has been put on methods to create quaternary carbon stereocenters, including syntheses of the same natural product by different groups, thereby showcasing the diversity of thought and individual creativity. A compendium of selected natural products containing two or more contiguous stereogenic quaternary carbon atoms and key reactions in their total or partial syntheses is provided in the Supporting Information.

  2. Different behavior toward muscarinic receptor binding between quaternary anticholinergics and their tertiary analogues.

    PubMed

    Ensing, K; de Zeeuw, R A

    1986-12-01

    A number of corresponding tertiary and quaternary anticholinergic analogues were examined for their ability to inhibit specific (3)H-dexetimide binding to calf brain muscarinic receptors. In all cases the tertiary antagonists (except pirenzepine) showed steep and monophasic inhibition curves, whereas those of the quaternary derivatives were shallow (thiazinamium, methylbenactyzine) or even biphasic (oxyphenonium, methylatropine, methylscopolamine). These observations show that the addition of a methyl group to the nitrogen atom changes the mode of interaction of the anticholinergics to muscarinic receptor binding sites. Whether there are separate binding sites present or differences in interaction mode for only the quaternary moiety is discussed. PMID:24271831

  3. Evaluation of chitosan quaternary ammonium salt-modified resin denture base material.

    PubMed

    Song, Rong; Zhong, Zhaohua; Lin, Lexun

    2016-04-01

    Chitosan quaternary ammonium salt displays good antioxidant and antibacterial characteristics and it shows appreciable solubility in water. When added to the traditional denture material to form a resin base, it could promote good oral health by improving the oral environment. In this study, chitosan quaternary ammonium salt was added to the denture material following two different methods. After three months of immersion in artificial saliva, the specimens were tested for tensile strength and were scanned by electron microscope. The murine fibroblast cytotoxicity and antibacterial properties were also tested. The result showed no significant differences in the tensile strength and in the proliferation of murine L929 fibroblast cells. The two structures of chitosan quaternary ammonium salt-modified denture material had different degrees of corrosion resistance and antimicrobial properties. These results indicate that chitosan quaternary ammonium salt-modified resin denture base material has the potential to become a new generation oral denture composite material.

  4. Induction of contact drematitis in guinea pigs by quaternary ammonium compounds: the mechanisms of antigen formation

    SciTech Connect

    Schallreuter, K.R.; Schulz, K.H.; Wood, J.M.

    1986-12-01

    Eight quaternary ammonium compounds were tested for their ability to induce contact dermatitis in guinea pigs by using a modified Freund's complete adjuvant test together with the guinea pig maximization test. Only two quaternary ammonium salts of eight tested could be designated as strong allergens. These two active substances were shown to be capable of stable association with membrane lipids in forming immunogenic complexes. This surface complexation phenomenon was confirmed by using a spin-labeled quaternary ammonium salt which competed for binding sites to the surface of epidermal cells in vivo. Electron spin resonance was used to demonstrate that stable ion-pairs are formed between binding sites and the two allergenic preservatives. Furthermore, information was obtained on the kinetics of immunogenic complex formation as well as on the position and orientation of the quaternary ammonium ion at the cell surface.

  5. Thermally Reduced Graphene Oxide Electrochemically Activated by Bis-Spiro Quaternary Alkyl Ammonium for Capacitors.

    PubMed

    He, Tieshi; Meng, Xiangling; Nie, Junping; Tong, Yujin; Cai, Kedi

    2016-06-01

    Thermally reduced graphene oxide (RGO) electrochemically activated by a quaternary alkyl ammonium-based organic electrolytes/activated carbon (AC) electrode asymmetric capacitor is proposed. The electrochemical activation process includes adsorption of anions into the pores of AC in the positive electrode and the interlayer intercalation of cations into RGO in the negative electrode under high potential (4.0 V). The EA process of RGO by quaternary alkyl ammonium was investigated by X-ray diffraction and electrochemical measurements, and the effects of cation size and structure were extensively evaluated. Intercalation by quaternary alkyl ammonium demonstrates a small degree of expansion of the whole crystal lattice (d002) and a large degree of expansion of the partial crystal lattice (d002) of RGO. RGO electrochemically activated by bis-spiro quaternary alkyl ammonium in propylene carbonate/AC asymmetric capacitor exhibits good activated efficiency, high specific capacity, and stable cyclability.

  6. OMVPE Growth of Quaternary (Al,Ga,In)N for UV Optoelectronics (title change from A)

    SciTech Connect

    HAN,JUNG; FIGIEL,JEFFREY J.; PETERSEN,GARY A.; MYERS JR.,SAMUEL M.; CRAWFORD,MARY H.; BANAS,MICHAEL ANTHONY; HEARNE,SEAN JOSEPH

    2000-01-18

    We report the growth and characterization of quaternary AlGaInN. A combination of photoluminescence (PL), high-resolution x-ray diffraction (XRD), and Rutherford backscattering spectrometry (RBS) characterizations enables us to explore the contours of constant PL peak energy and lattice parameter as functions of the quaternary compositions. The observation of room temperature PL emission at 351nm (with 20% Al and 5% In) renders initial evidence that the quaternary could be used to provide confinement for GaInN (and possibly GaN). AlGaInN/GrdnN MQW heterostructures have been grown; both XRD and PL measurements suggest the possibility of incorporating this quaternary into optoelectronic devices.

  7. Map and data for Quaternary faults and folds in Washington state

    USGS Publications Warehouse

    Lidke, David J.; Johnson, Samuel Y.; McCrory, Patricia A.; Personius, Stephen F.; Nelson, Alan R.; Dart, Richard L.; Bradley, Lee-Ann; Haller, Kathleen M.; Machette, Michael N.

    2004-01-01

    The map shows faults and folds in Washington State that exhibit evidence of Quaternary deformation and includes data on timing of most recent movement, sense of movement, slip rate, and continuity of surface expression.

  8. Enantioselective synthesis of benzazepinoindoles bearing trifluoromethylated quaternary stereocenters catalyzed by chiral spirocyclic phosphoric acids.

    PubMed

    Li, Xuejian; Chen, Di; Gu, Haorui; Lin, Xufeng

    2014-07-18

    The first highly enantioselective iso-Pictet-Spengler reaction of C-2-linked o-aminobenzylindoles with trifluoromethyl ketones was developed using chiral spirocyclic phosphoric acids as organocatalysts, which afforded optically active benzazepinoindoles bearing trifluoromethylated quaternary stereocenters. PMID:24890313

  9. Thermally Reduced Graphene Oxide Electrochemically Activated by Bis-Spiro Quaternary Alkyl Ammonium for Capacitors.

    PubMed

    He, Tieshi; Meng, Xiangling; Nie, Junping; Tong, Yujin; Cai, Kedi

    2016-06-01

    Thermally reduced graphene oxide (RGO) electrochemically activated by a quaternary alkyl ammonium-based organic electrolytes/activated carbon (AC) electrode asymmetric capacitor is proposed. The electrochemical activation process includes adsorption of anions into the pores of AC in the positive electrode and the interlayer intercalation of cations into RGO in the negative electrode under high potential (4.0 V). The EA process of RGO by quaternary alkyl ammonium was investigated by X-ray diffraction and electrochemical measurements, and the effects of cation size and structure were extensively evaluated. Intercalation by quaternary alkyl ammonium demonstrates a small degree of expansion of the whole crystal lattice (d002) and a large degree of expansion of the partial crystal lattice (d002) of RGO. RGO electrochemically activated by bis-spiro quaternary alkyl ammonium in propylene carbonate/AC asymmetric capacitor exhibits good activated efficiency, high specific capacity, and stable cyclability. PMID:27180820

  10. A comparative study of ICH validated novel spectrophotometric techniques for resolving completely overlapping spectra of quaternary mixtures

    NASA Astrophysics Data System (ADS)

    Ali, Nouruddin W.; Abdelwahab, Nada S.; Abdelkawy, M.; Emam, Aml A.

    2016-02-01

    A pharmaceutically marketed mixture of Yohimbine, Alpha-tocopheryl acetate, Niacin, and Caffeine co-formulated as a promising therapy for erectile dysfunction. Simultaneous determination of the aforementioned pharmaceutical formulation without prior separation steps was applied using mean centering of ratio spectra and triple divisor spectrophotometric methods. Mean centering of ratio spectra method depended on using the mean centered ratio spectra in three successive steps which eliminated the derivative steps and so the signal to noise ratio was improved. The absorption spectra of the prepared solutions were measured in the wavelength range of 215-300 nm in the concentration ranges of 1-15, 3-15, 1-20, and 3-15 μg mL- 1 for Yohimbine, Alpha-tocopheryl acetate, Niacin, and Caffeine, respectively. The amplitudes of the mean centered third ratio spectra were measured at 250 nm and 268 nm for Yohimbine and Alpha-tocopheryl acetate, respectively and at peak to peak 272-273 and 262-263 nm for Niacin and Caffeine, respectively. In triple divisor method each drug in the quaternary mixture was determined by dividing the spectrum of the quaternary mixture by a standard spectrum of a mixture containing equal concentrations of the other three drugs. First derivative of these ratio spectra was obtained where determination could be achieved without any interference from the other three drugs. Amplitudes of 1-15, 3-15, 1-15, and 3-15 μg mL- 1 were used for selective determination of Yohimbine, Alpha-tocopheryl acetate, Niacin, and Caffeine, respectively. Laboratory prepared mixtures were analyzed by the developed novel methods to investigate their selectivity also, Super Act® capsules were successfully analyzed to ensure absence of interference from additives. The developed methods were validated according to the ICH guidelines. The proposed methods were statistically compared with each other and with the reported methods; using student t-test, F-test, and one way ANOVA

  11. The role of Quaternary environmental change in plant macroevolution: the exception or the rule?

    PubMed Central

    Willis, Katherine J; Niklas, Karl J

    2004-01-01

    The Quaternary has been described as an important time for genetic diversification and speciation. This is based on the premise that Quaternary climatic conditions fostered the isolation of populations and, in some instances, allopatric speciation. However, the 'Quaternary Ice-Age speciation model' rests on two key assumptions: (i) that biotic responses to climate change during the Quaternary were significantly different from those of other periods in Earth's history; and (ii) that the mechanisms of isolation during the Quaternary were sufficient in time and space for genetic diversification to foster speciation. These assumptions are addressed by examining the plant fossil record for the Quaternary (in detail) and for the past 410 Myr, which encompasses previous intervals of icehouse Earth. Our examination of the Quaternary record indicates that floristic responses to climate changes during the past 1.8 Myr were complex and that a distinction has to be made between those plants that were able to withstand the extremes of glacial conditions and those that could not. Generation times are also important as are different growth forms (e.g. herbaceous annuals and arborescent perennials), resulting in different responses in terms of genetic divergence rates during isolation. Because of these variations in the duration of isolation of populations and genomic diversification rates, no canonical statement about the predominant floristic response to climatic changes during the Quaternary (i.e. elevated rates of speciation or extinction, or stasis) is currently possible. This is especially true because of a sampling bias in terms of the fossil record of tree species over that of species with non-arborescent growth forms. Nevertheless, based on the available information, it appears that the dominant response of arborescent species during the Quaternary was extinction rather than speciation or stasis. By contrast, our examination of the fossil record of vascular plants for the

  12. Use of quaternary ammonium salts of nitrogen containing polymers for improved carburetor detergency

    SciTech Connect

    Biasotti, J.B.; Vartanian, P.F.

    1980-01-15

    A quaternary ammonium salt is described of a copolymer, said copolymer being the olefin polymerization product of: (A) a nitrogen amine free ester of a C/sub 1/-C/sub 6/ olefinically unsaturated aliphatic mono-, di-, or polycarboxylic acid having a tertiary nitrogen atom; and (B) an olefinically unsaturated co-monomer containing a basic nitrogen atom in a side chain; a fuel component, especially gasoline, containing such quaternary ammonium salt of such copolymer as a detergent.

  13. Quaternary Alkylammonium Conjugates of Steroids: Synthesis, Molecular Structure, and Biological Studies.

    PubMed

    Brycki, Bogumił; Koenig, Hanna; Pospieszny, Tomasz

    2015-11-23

    The methods of synthesis as well as physical, spectroscopic (¹H-NMR, 13C-NMR, and FT-IR, ESI-MS), and biological properties of quaternary and dimeric quaternary alkylammonium conjugates of steroids are presented. The results were contrasted with theoretical calculations (PM5 methods) and potential pharmacological properties (PASS). Alkylammonium sterols exhibit a broad spectrum of antimicrobial activity comparable to squalamine.

  14. Advances in the synthesis of α-quaternary α-ethynyl α-amino acids.

    PubMed

    Boibessot, Thibaut; Bénimélis, David; Meffre, Patrick; Benfodda, Zohra

    2016-09-01

    α-Quaternary α-ethynyl α-amino acids are an important class of non-proteinogenic amino acids that play an important role in the development of peptides and peptidomimetics as therapeutic agents and in the inhibition of enzyme activities. This review provides an overview of the literature concerning synthesis and applications of α-quaternary α-ethynyl α-amino acids covering the period from 1977 to 2015.

  15. Progress report. Task 1 - quaternary tectonics, 1 October 1991--30 September 1992

    SciTech Connect

    1992-09-30

    Progress is reported on a study concerned with the quaternary tectonics of Yucca Mountain, the proposed site for an underground disposal facility for high-level radioactive wastes. Refinement and revision of crater Flat Quaternary stratigraphy continued and consisted of several activities: revision of rock varnish cation leaching curve; sample comparison of RV manganese;,iron microlaminations;and correlation of Crater Flat allostratigraphic units with regional chronologies.

  16. Quaternary Alkylammonium Conjugates of Steroids: Synthesis, Molecular Structure, and Biological Studies.

    PubMed

    Brycki, Bogumił; Koenig, Hanna; Pospieszny, Tomasz

    2015-01-01

    The methods of synthesis as well as physical, spectroscopic (¹H-NMR, 13C-NMR, and FT-IR, ESI-MS), and biological properties of quaternary and dimeric quaternary alkylammonium conjugates of steroids are presented. The results were contrasted with theoretical calculations (PM5 methods) and potential pharmacological properties (PASS). Alkylammonium sterols exhibit a broad spectrum of antimicrobial activity comparable to squalamine. PMID:26610455

  17. The pragmatic roots of American Quaternary geology and geomorphology

    NASA Astrophysics Data System (ADS)

    Baker, Victor R.

    1996-07-01

    H.L. Fairchild's words from the 1904 Geological Society of America Bulletin remain appropriate today: "Geologists have been too generous in allowing other people to make their philosophy for them". Geologists have quietly followed a methodological trinity involving (1) inspiration by analogy, (2) impartial and critical assessment of hypotheses, and (3) skepticism of authority (prevailing theoretical constraints or paradigms). These methods are described in classical papers by Quaternary geologists and geomorphologists, mostly written a century ago. In recent years these papers have all been criticized in modern philosophical terms with little appreciation for the late 19th century American philosophical tradition from which they arose. Recent scholarly research, however, has revealed some important aspects of that tradition, giving it a coherence that has largely been underappreciated as 20th century philosophy of science pursued its successive fads of logical positivism, critical rationalism, relativism, and deconstructivism — for all of which "science" is synonymous with "physics". Nearly all this ideology is geologically irrelevant. As philosophy of science in the late 20th century has come to be identical with philosophy of analytical physics, focused on explanations via ideal truths, much of geology has remained true to its classical doctrines of commonsensism, fallibilism, and realism. In contrast to the conceptualism and the reductionism of the analytical sciences, geology has emphasized synthetic thinking: the continuous activity of comparing, connecting, and putting together thoughts and perceptions. The classical methodological studies of geological reasoning all concern the formulation and testing of hypotheses. Analysis does not serve to provide the ultimate answers for intellectual puzzles predefined by limiting assumptions imposed on the real world. Rather, analysis in geology allows the investigator to consider the consequential effects of

  18. Three-dimensional, geological representation of Quaternary deposits, Goettingen, Germany

    NASA Astrophysics Data System (ADS)

    Thomas, Katrin; Wagner, Bianca

    2010-05-01

    The Quaternary unconsolidated rock in north-eastern Goettingen was newly interpreted according to current scientific expertise. Especially the deposits of the Lutter River, a tributary to the Leine River, were examined using 253 drillings previously undertaken to create 24 two-dimensional cross-sections and a three-dimensional model of the geologic underground in the study area. The interpretation of the included data (drillings, previous studies, two-dimensional cross-sections) resulted in a stratigraphic sequence with 17 Quaternary model units, which was depicted three-dimensionally. During the investigation period, open pits were limited in the entire working area. Natural outcrops of Quaternary subsurfaces are absent. For the creation of a two-dimensional and three-dimensional representation of the geologic structure, it was necessary to fall back on available information of drillings. The spatial distribution of the drilling information in the scope of work is very heterogeneous. In addition, numerous engineer-geologic surveys were used for the interpretation and interpolation within areas where no other information could be obtained by drilling within this study. The production of a three-dimensional illustration of the unconsolidated rock first required an exact investigation and homogenisation of all available information. The choice of the drillings used in the scope of work were chosen with priority according to their depth with the aid of ArcMap. Two-dimensional cross-sections of the profiles of these drillings were produced with the help of the computer program GeoDin. Using the two-dimensional cross sections, the drillings were correlated with each other and compared and discussed extensively. The sequence of the geologic unities thereby presented itself more clearly and more exactly than in linear consideration. A geologic unity could be assigned to every examined layer of each drilling. Additionally, a top and a base were assigned to each geologic

  19. Electrodeposition of iron-cobalt-nickel-copper quaternary system

    NASA Astrophysics Data System (ADS)

    Huang, Qiang

    Electrodeposition is a cost-effective method to produce thin film materials, which have been used widely in the microelectronic industry, and is advantageous to fabricate metal deposits into recessed and curved areas. In this dissertation, a FeCoNiCu quaternary alloy system was investigated, both experimentally and theoretically, for fabrication of multilayers, grating structures, and nanowires. Multilayer structures are composed of alternating ferromagnetic and nonmagnetic nanometric layers, and are of interest due to the giant magnetoresistance (GMR) property it possesses, a change in electric resistance in the presence of an external magnetic field. In addition, the compositional modulation, or the composition contrast, in multilayer structures can be used to develop a grating structured mold for the development of a novel nanoimprinting process. FeCoNiCu was investigated as a more general alloy system containing iron-group metals and a nonmagnetic element, Cu, which can be simplified and adapted to any binary or ternary systems. With a dilute tartrate sulfate bath nanometric multilayers were successfully fabricated with pulse plating and GMR value was reported for this electrodeposited system for the first time. A value of -6% was achieved on rotating disk electrode (RDE) and this maximum occurred when the structure had no preferred crystal phase. Over 40% GMR has been achieved when the multilayer was plated onto a polycrystalline Cu foil. A mathematical model was developed to tailor the deposition process on RDE, and both steady state and nonsteady state cases were simulated. A compositional gradient, which is inherent to a nonsteady state deposition process when the layer size is of nanometer scale was predicted. The quaternary system was explored for other applications. Selective etching of electrodeposited multilayer structures was investigated for different etching solutions. A diluted K2Cr2O 7/H2SO4 solution was successfully developed to produce grating

  20. Quaternary ammonium derivatives as spasmolytics for irritable bowel syndrome.

    PubMed

    Evangelista, S

    2004-01-01

    Quaternary ammonium derivatives such as cimetropium, n-butyl scopolammonium, otilonium and pinaverium bromide have been discovered and developed as potent spasmolytics of the gastrointestinal tract. Their pharmacological activity has been proven in both "in vivo" and "in vitro" studies of hypermotility. "In vitro" experiments showed that they possess antimuscarinic activity at nM level but only pinaverium and otilonium are endowed with calcium channel blocker properties. These latter compounds relaxed the gastrointestinal smooth muscle mainly through a specific inhibition of calcium ion influx through L-type voltage operated calcium channels. Molecular pharmacology trials have indicated that pinaverium and otilonium can bind specific subunits of the calcium channel in the external surface of the plasma membrane and in this way they block the machinery of the contraction. Recent evidence showed that otilonium is able to bind tachykinin NK(2) receptors and not only inhibits one of the major contractile agents but can reduce the activation of afferent nerves devoted to the passage of sensory signals from the periphery to the central nervous system. Thanks to their typical physico-chemical characteristics, they are poorly absorbed by the systemic circulation and generally remain in the gastrointestinal tract where they exert the muscle relaxant activity by a local activity. Some differences exists in the absorption among these compounds: both n-butyl scopolammonium and cimetropium are partially taken up in the bloodstream, pinaverium has a low absorption (8-10 %) but is endowed with an excellent hepato-biliary excretion and otilonium, which has the lowest absorption (3 %), is almost totally excreted by faeces. Quaternary ammonium derivatives are widely used for the treatment of irritable bowel syndrome and recent meta-analyses have supported their efficacy in this disease. Due to its therapeutic index, the use of n-butyl scopolammonium is more indicated to treat acute

  1. Late Quaternary carbonate deposition at the bottom of the world

    NASA Astrophysics Data System (ADS)

    Frank, Tracy D.; James, Noel P.; Bone, Yvonne; Malcolm, Isabelle; Bobak, Lindsey E.

    2014-05-01

    Carbonate sediments on polar shelves hold great potential for improving understanding of climate and oceanography in regions of the globe that are particularly sensitive to global change. Such deposits have, however, not received much attention from sedimentologists and thus remain poorly understood. This study investigates the distribution, composition, diagenesis, and stratigraphic context of Late Quaternary calcareous sediments recovered in 15 piston cores from the Ross Sea shelf, Antarctica. Results are used to develop a depositional model for carbonate deposition on glaciated, polar shelves. The utility of the deposits as analogs for the ancient record is explored. In the Ross Sea, carbonate-rich lithofacies, consisting of poorly sorted skeletal sand and gravel, are concentrated in the west and along the outer reaches of the continental shelf and upper slope. Analysis of fossil assemblages shows that deposits were produced by numerous low-diversity benthic communities dominated locally by stylasterine hydrocorals, barnacles, or bryozoans. Radiocarbon dating indicates that carbonate sedimentation was episodic, corresponding to times of reduced siliciclastic deposition. Most accumulation occurred during a time of glacial expansion in the lead-up to the Last Glacial Maximum. A more recent interval of carbonate accumulation postdates the early Holocene sea level rise and the establishment of the modern grounding line for the Ross Ice Shelf. When carbonate factories were inactive, fossil debris was subjected to infestation by bioeroders, dissolution, fragmentation, and physical reworking. This study reveals the episodic nature of carbonate deposition in polar settings and a reciprocal relationship with processes that deliver and redistribute siliciclastic debris. Carbonate production is most active during colder periods of the glacial-interglacial cycle, a potential new sedimentological paradigm for polar carbonate systems. Low accumulation rates and long residence

  2. A model of the Quaternary geological deposits of Bucharest City

    NASA Astrophysics Data System (ADS)

    Serpescu, Irina; Radu, Emil; Radu Gogu, Constantin; Amine Boukhemacha, Mohamed; Gaitanaru, Dragos; Bica, Ioan

    2013-04-01

    Bucharest city is located in the central part of the Moesic Platform, in the Romanian Plain with micro-relief resulting from erosion and sedimentary processes which extended along the valleys of the Dambovita River to the south and the Colentina River to the north. The city is located in the axial area of a syncline where the thickness of the sedimentary deposits is up to 1000 m. The area lies on a rigid base is made of metamorphites, and various igneous intrusions (granodiorite, granite). The sedimentary deposits covering this rigid base are made by different phases of erosion and sedimentary processes of marine, lacustrian or continental sediments ending with Quaternary sediments. As a result, different alluvial deposits (such as piedmont, deltaic, alluvial cones, terrace, waterside and lacustrine deposits) can be met. Furthermore one also can find loess deposits which in turn cover totally the older deposits where rivers dug the present relief. To highlight the spatial extent of these geological structures, a geological model of Bucharest city is developed. A set of information coming from different sources as geological and geotechnical boreholes showing a detailed geological and lithological description, geological and topographical maps, geological and hydrogeological reports have been used to develop the 3D geological model of this region. 33 geological cross sections were defined and interpreted by using lithological and sedimentological criteria. Using these geological cross sections and prior geological knowledge, the Quaternary deposits have been described and classified into 6 structural units given from top to down as follows: (1) Superficial deposits represented by loess and anthropogenic materials. The geological model indicates that these deposits show a sporadic development becoming more concentrated in the central west part of the city. (2) Colentina Formations composed by of poorly sorted, cross-stratified sand and gravel with clayey lens

  3. Quaternary continetal back-arc evolution from southern Mendoza, Argentina

    NASA Astrophysics Data System (ADS)

    Espanon, Venera; Chivas, Allan; Dosseto, Anthony; Honda, Masahiko; Phillips, David; Matchan, Erin; Price, David

    2016-04-01

    The Quaternary evolution of the Payenia Basaltic Province (PBP) in southern Mendoza, Argentina has been investigated using a multi-dating approach in combination with pre-exiting geochemical data. This basaltic province covers an area of approximately 40000 km2 and is mainly characterised by backarc volcanism. In the current investigation nine new radiometric ages obtained using surface exposure, 40Ar/39Ar and thermoluminescence dating are presented. Six ages correspond to the late Pleistocene and three to the Holocene. The surface exposure ages obtained using cosmogenic 3He and 21Ne are in good agreement with previous publications and confidently suggest that part of this basaltic province was active at least 4000 years ago (taking a conservative approach). In addition, we combined the available geochronological and geochemical data to reconstruct the Quaternary evolution of this basaltic province. This approach was used to create maps of geospatial distribution of trace-element ratios to determine geochemical changes during the Pleistocene. Employing this method it is evident that two geochemical distinct types of magma were erupting at the same time interval within the PBP. In the north eastern part (Nevado volcanic field) of the PBP an arc-like signature is evident, while in the southern part (Río Colorado volcanic field) of the same basaltic province an Ocean Island Basalt (OIB) signature is evident. The arc-like signature in the north eastern part of the PBP, decreased during the Pleistocene in a north-west direction indicated by a reduction in Ba/La and La/Ta in the Nevado and Llancanelo volcanic field. The Holocene volcanism is restricted to the western side of the Payún Matrú volcanic field and is dominated by OIB-like signatures such as high Ta/Hf and low Ba/La and La/Ta. This contribution presents new geochronology for the PBP and confirms that two different types of volcanism occurred simultaneously during the Pleistocene, while the Holocene

  4. Quaternary Deformation of Sumba, Indonesia: Evidence from Carbonate Terraces

    NASA Astrophysics Data System (ADS)

    Dahlquist, M. P.; West, A. J.; Dolan, J. F.

    2014-12-01

    The Banda Arc of Indonesia remains one of the least understood tectonic domains on the modern Earth. The island of Sumba, located approximately 50 km south of Flores and 120 km north of the Java Trench, northwest of where it transitions into the Timor Trough, lies in a region of tectonic transition and potentially offers insights into regional dynamics. The Banda Arc is volcanically active, but Sumba itself is not volcanic. The northern coast of Sumba is covered in Quaternary coral terraces, with the rest of the island's surface geology composed of Mio-pliocene carbonates and uplifted Late Cretaceous-Oligocene forearc basin and volcanic rocks. The purpose of this study is to remotely map the topographic expression of the coral terraces and use the information gained to better understand deformation on Sumba since their deposition. The ages of the coral terraces, of which many platforms are exposed over significant areas of the island, have been constrained at Cape Luandi in north central Sumba, but uplift rates calculated from those ages may not be representative of the island as a whole. The lateral continuity of these dated terraces can help constrain the extent to which uplift of Sumba is spatially variable. Analysis of the terraces using SRTM digital elevation data with ArcGIS software makes it possible to trace the same terrace platforms over large distances, and shows that the north central part of the island has experienced the most uplift since the deposition of the terraces, forming an anticline with the east limb dipping more steeply than the west. The terraces are not well preserved on the southern half of the island. Exposure of older rocks and lack of terrace preservation, as well as a south-skewed drainage divide suggests the southern half of the island experiences greater exhumation, but this could be driven by climate or other factors and does not necessarily indicate more rapid uplift. Study of Quaternary deformation of Sumba can offer greater

  5. Regulated assembly and disassembly of the yeast telomerase quaternary complex

    PubMed Central

    Tucey, Timothy M.

    2014-01-01

    The enzyme telomerase, which elongates chromosome termini, is a critical factor in determining long-term cellular proliferation and tissue renewal. Hence, even small differences in telomerase levels can have substantial consequences for human health. In budding yeast, telomerase consists of the catalytic Est2 protein and two regulatory subunits (Est1 and Est3) in association with the TLC1 RNA, with each of the four subunits essential for in vivo telomerase function. We show here that a hierarchy of assembly and disassembly results in limiting amounts of the quaternary complex late in the cell cycle, following completion of DNA replication. The assembly pathway, which is driven by interaction of the Est3 telomerase subunit with a previously formed Est1–TLC1–Est2 preassembly complex, is highly regulated, involving Est3-binding sites on both Est2 and Est1 as well as an interface on Est3 itself that functions as a toggle switch. Telomerase subsequently disassembles by a mechanistically distinct pathway due to dissociation of the catalytic subunit from the complex in every cell cycle. The balance between the assembly and disassembly pathways, which dictate the levels of the active holoenzyme in the cell, reveals a novel mechanism by which telomerase (and hence telomere homeostasis) is regulated. PMID:25240060

  6. Formation of Late Quaternary paleoshorelines in Crete, Eastern Mediterranean

    NASA Astrophysics Data System (ADS)

    Mouslopoulou, Vasiliki; Begg, John; Nicol, Andrew; Oncken, Onno; Prior, Christine

    2015-12-01

    Paleoshorelines of Late Quaternary age in western Crete do not exclusively increase in age with rising altitude as is generally observed worldwide. At numerous sites, for example, Late-Holocene paleoshorelines decrease in age with increasing altitude while in other cases paleoshorelines at similar altitude vary in age by tens of thousands of years. We propose that the observed paleoshoreline altitude-age relationships can be accounted for by eustatic sea-level changes and tectonic rock uplift without requiring substantial errors on radiocarbon ages or tectonic subsidence, as has been previously proposed. To test this model we use a dataset consisting of altitude and age data for 71 individual paleoshorelines sampled from 21 sites distributed along the entire Cretan coastline. These data include radiocarbon ages of marine biota (40 new dates) within beachrock resting on paleoshorelines ranging up to 48 kyr BP in age and ≤20 m above present sea-level. We find that paleoshoreline formation reflects Late Holocene tectonic rock uplift in western Crete, preceded by eustatic sea-level rise and by >10 kyr BP rock uplift along the entire island. Our observations contravene existing models as they suggest that some paleoshorelines, and their associated lithified beachrock, survived passage through the wave-zone multiple times and formed throughout the sea-level cycle (i.e., preservation is not restricted to highstand deposits). These results may have application globally in regions where erosion-resistant carbonate beachrock mantles paleoshorelines.

  7. Facilitating Progress on the Quaternary History of Sea Level Change

    NASA Astrophysics Data System (ADS)

    Thompson, W. G.; Andersen, M. B.

    2010-04-01

    Understanding Future Sea Level Rise: The Challenges of Dating Past Interglacials; Woods Hole, Massachusetts, 20-25 September 2009; Substantial uncertainty exists in projections of future sea level rise, due primarily to a lack of understanding about ice sheet dynamics. Paleo Constraints on Sea Level Rise (PALSEA) is a working group of the Past Global Changes (PAGES) project and the International Marine Global Change Studies (IMAGES) program that aims to extract information about ice sheet response to temperature change by examining the history of sea level over the Quaternary (spanning the past ˜2.5 million years). In particular, PALSEA focuses on the past 800,000 years, particularly interglacial periods, with a range of temperatures bracketing the modern. PALSEA recently held a workshop at Woods Hole Oceanographic Institution (WHOI). Funded by IMAGES, PAGES, and WHOI's Ocean and Climate Change Institute, the workshop focused on challenges in uranium-thorium (U-Th) coral dating. The meeting also included a public outreach event, “Where land and sea meet: Managing shoreline change over the next 100 years,” funded by WHOI's Morss Colloquium.

  8. Late Quaternary sea-level changes of the Persian Gulf

    NASA Astrophysics Data System (ADS)

    Lokier, Stephen W.; Bateman, Mark D.; Larkin, Nigel R.; Rye, Philip; Stewart, John R.

    2015-07-01

    Late Quaternary reflooding of the Persian Gulf climaxed with the mid-Holocene highstand previously variously dated between 6 and 3.4 ka. Examination of the stratigraphic and paleoenvironmental context of a mid-Holocene whale beaching allows us to accurately constrain the timing of the transgressive, highstand and regressive phases of the mid- to late Holocene sea-level highstand in the Persian Gulf. Mid-Holocene transgression of the Gulf surpassed today's sea level by 7100-6890 cal yr BP, attaining a highstand of > 1 m above current sea level shortly after 5290-4570 cal yr BP before falling back to current levels by 1440-1170 cal yr BP. The cetacean beached into an intertidal hardground pond during the transgressive phase (5300-4960 cal yr BP) with continued transgression interring the skeleton in shallow-subtidal sediments. Subsequent relative sea-level fall produced a forced regression with consequent progradation of the coastal system. These new ages refine previously reported timings for the mid- to late Holocene sea-level highstand published for other regions. By so doing, they allow us to constrain the timing of this correlatable global eustatic event more accurately.

  9. Late Quaternary shelf-margin deltas, northwest Gulf of Mexico

    SciTech Connect

    Suter, J.R.; Berryhill, H.L. Jr.

    1985-12-01

    Interpretations of 35,000 km (21,900 mi) of single-channel, high-resolution, seismic profiles traversing the continental shelf and upper continental slope of the northwest Gulf of Mexico indicate the existence of five late Wisconsinan shelf margin deltas, including the Rio Grande and Mississippi deltas. The deltas were recognized by geomorphic pattern, high-angle clinoform seismic reflections, and associated with buried river systems. Isopach patterns show that the deltas range in size up to 5000 km/sup 2/ (1900 mi/sup 2/) and reach thicknesses of over 180 m (590 ft). The deposits are elongate parallel with depositional strike, indicating subsidence of the shelf margin as a whole. Internal reflection patterns show the deltas to be fluvially dominated. Multilobate structure resulted from both short-term eustatic sea level fluctuations and delta switching. The late Quaternary shelf-margin deltas provide models for analogous deposits in the ancient record. They are primary indicators of the position of ancient shelf margins, and are important for predicting sand occurrence in that environment as well as farther downslope. As exploration moves to the shelf edge and beyond, instability hazards posed by late Wisconsin deltas, as well as older deposits, must be understood and dealt with. 20 figures.

  10. Late quaternary shelf-margin deltas, northwest Gulf of Mexico

    SciTech Connect

    Suter, J.R.; Berryhill, H.L.

    1985-01-01

    Interpretations of 35,000 km (21,900 mi) of single-channel, high-resolution, seismic profiles traversing the continental shelf and upper continental slope of the northwest Gulf of Mexico indicate the existence of five late Wisconsinan shelf margin deltas, including the Rio Grande and Mississippi deltas. The deltas were recognized by geomorphic pattern, high-angle clinoform seismic reflections, and association with buried river systems. Isopach patterns show that the deltas range in size up to 5,000 km/sup 2/ (1,900 mi/sup 2/) and reach thicknesses of over 180 m (590 ft). The deposits are elongate parallel with depositional strike, indicating subsidence of the shelf margin as a whole. Internal reflection patterns show the deltas to be fluvially dominated. Multilobate structure resulted from both short-term eustatic sea level fluctuations and delta switching. The late Quaternary shelf-margin deltas provide models for analogous deposits in the ancient record. They are primary indicators of the position of ancient shelf margins, and are important for predicting sand occurrence in that environment as well as farther downslope. As exploration moves to the shelf edge and beyond, instability hazards posed by late Wisconsinan deltas, as well as older deposits, must be understood and dealt with.

  11. A Quaternary volcanic ash deposit in western Missouri

    SciTech Connect

    Emerson, J.W. )

    1993-03-01

    Quaternary volcanic ash has been found in more than fifty localities in the midwest. The most widespread deposits originated from the Long Valley caldera, California; the Jemez calderas, New Mexico; or the Yellowstone caldera, Wyoming. Fission track dating has grouped the deposits into six separate ash falls ranging from 700,000--2,000,000 years old. A small volcanic ash deposit in western Missouri may be correlative with those found along the Kansas and Marais de Cygnes rivers in eastern Kansas. The ash deposit is in Northwest Bates County Missouri, exposed along a tributary to Miami Creek, four miles east of the Kansas state line. The ash layer is interbedded with alluvial terrace deposits and ranges from fifteen to thirty inches in thickness. It is inferred to have been deposited in a pond or oxbow lake. The color is white with a pale yellow tinge (Munsell 10YR 8/2). Shard examination shows that about 70% are flat bubble-wall types, about 20% have straight ridges, less than 10% are bubble-junction, and only a trace are vesicular. The closest known volcanic ash occurrence is an ash outcropping in a Kansas river terrace near DeSoto, KS, forty-five miles to the northwest. The DeSoto deposit has been identified as the .62 m.y. Lava Creek B ash from the Yellowstone caldera. A preliminary correlation of the Missouri ash with the DeSoto ash is based on similar shard morphology and color.

  12. Liquid chromatography of hydrocarbonaeous quaternary amines on cyclodextrin bonded silica

    USGS Publications Warehouse

    Abidi, S.L.

    1986-01-01

    Mixtures of n-alkylbenzyldimethylammonium chloride (ABDAC) were resolved into homologous components by high-performance liquid chromatography (HPLC) with a cyclodextrin-bonded silica stationary phase. With a few exceptions, results from this study are similar to those obtained from traditional reversed-phase HPLC. It was found that the presence of electrolytes in aqueous mobile phases is not a critical factor in determining the success of HPLC separation. Under normal HPLC conditions, a mobile phase consisting of either methanol–water (50:50) or acetonitrile–water (30:70) was employed for obtaining adequate resolution of the quaternary ammonium mixtures. Although the percent organic modifier–water profiles were similar to those in previous studies with these compounds, resolution (R) and selectivity (α) parameters were found to be quite susceptible to changes in the mobile phase solvent composition. The retention behavior of the cationic analytes in the homologous series is consistent with the hydrophobic-interaction concept proposed for the retention mechanism via dominant inclusion complex formation. Several electrolytes were chosen for a study of the counter ion effect on the chromatographic characteristics of ABDAC components. Among the electrolytes examined, the perchlorate ion was found most likely to act as an ion-pairing counter ion for ammonium cations in the HPLC system studied. A correlation study established linear relationships between the chain length of ABDAC and the logarithmic capacity factor (k2). The analytical utility of the HPLC method was demonstrated by the analysis of various unknown mixtures.

  13. Quaternary geochronology using the U-Th-Pb method

    SciTech Connect

    Getty, S.R.; DePaolo, D.J.

    1995-08-01

    We describe a method of uranium-thorium-lead (U-Th-Pb) isotopic age dating for Quaternary rocks. The approach uses an instrumental mass discrimination correction for lead isotope ratios, which allows small enrichments of radiogenic {sup 206}Pb and {sup 208}Pb to be detected at the level of 0.001%. Igneous rocks hosting minerals with a range in {sup 238}U/{sup 204}Pb values of 100 can be dated with uncertainties of approximately {+-}15-20 kyr. A Quarternary rhyolite dated at 1.19 Ma by K-Ar yields a {sup 238}U-{sup 206}Pb age of 1.03{+-}0.10 Ma. A Holocene dacite (9.5 ka) has uniform {sup 206}Pb/{sup 207}Pb to within {+-}0.0015% in groundmass phases, but 1 mm plagioclase phenocrysts have lower {sup 206}Pb/{sup 207}Pb by 0.105{+-}0.002% indicating contamination of the magma after plagioclase crystallization. High precision {sup 206}Pb/{sup 207}Pb ratios may be a useful new tool for petrogenetic studies.

  14. Effects of late quaternary climate change on Palearctic shrews.

    PubMed

    Prost, Stefan; Klietmann, Johannes; van Kolfschoten, Thijs; Guralnick, Robert P; Waltari, Eric; Vrieling, Klaas; Stiller, Mathias; Nagel, Doris; Rabeder, Gernot; Hofreiter, Michael; Sommer, Robert S

    2013-06-01

    The Late Quaternary was a time of rapid climatic oscillations and drastic environmental changes. In general, species can respond to such changes by behavioral accommodation, distributional shifts, ecophenotypic modifications (nongenetic), evolution (genetic) or ultimately face local extinction. How those responses manifested in the past is essential for properly predicting future ones especially as the current warm phase is further intensified by rising levels of atmospheric carbon dioxide. Here, we use ancient DNA (aDNA) and morphological features in combination with ecological niche modeling (ENM) to investigate genetic and nongenetic responses of Central European Palearctic shrews to past climatic change. We show that a giant form of shrew, previously described as an extinct Pleistocene Sorex species, represents a large ecomorph of the common shrew (Sorex araneus), which was replaced by populations from a different gene-pool and with different morphology after the Pleistocene Holocene transition. We also report the presence of the cold-adapted tundra shrew (S. tundrensis) in Central Europe. This species is currently restricted to Siberia and was hitherto unknown as an element of the Pleistocene fauna of Europe. Finally, we show that there is no clear correlation between climatic oscillations within the last 50 000 years and body size in shrews and conclude that a special nonanalogous situation with regard to biodiversity and food supply in the Late Glacial may have caused the observed large body size. PMID:23505017

  15. Interaction of ochratoxin A with quaternary ammonium beta-cyclodextrin.

    PubMed

    Poór, Miklós; Kunsági-Máté, Sándor; Szente, Lajos; Matisz, Gergely; Secenji, Györgyi; Czibulya, Zsuzsanna; Kőszegi, Tamás

    2015-04-01

    Ochratoxin A (OTA) is a widely spread nephrotoxic food contaminant mycotoxin. Unfortunately, attenuation or prevention of the toxic effects of OTA is still an unresolved problem. Molecular inclusion of OTA by cyclodextrins (CDs) results in complexes with low stability. In the human organism, OTA exists mostly in the dianionic state (OTA(2-)). Therefore, our major goal was to develop a chemically modified cyclodextrin which gives a more stable complex with OTA than the previously published derivatives and which shows stronger preference towards OTA(2-). In our fluorescence spectroscopic study we demonstrate that quaternary ammonium beta-cyclodextrin (QABCD) fulfils both of these requirements. The calculated stability constant of the QABCD-OTA(2-) complex was 28,840 M(-1) (about 200-fold higher than that of the β-CD-OTA(2-) complex). We hypothesize, that QABCD may be a suitable tool for the decontamination of different OTA-contaminated drinks; furthermore, for alleviation of the toxic effects of OTA, such complex formation may reduce its absorption from the intestine. PMID:25442535

  16. Interaction of ochratoxin A with quaternary ammonium beta-cyclodextrin.

    PubMed

    Poór, Miklós; Kunsági-Máté, Sándor; Szente, Lajos; Matisz, Gergely; Secenji, Györgyi; Czibulya, Zsuzsanna; Kőszegi, Tamás

    2015-04-01

    Ochratoxin A (OTA) is a widely spread nephrotoxic food contaminant mycotoxin. Unfortunately, attenuation or prevention of the toxic effects of OTA is still an unresolved problem. Molecular inclusion of OTA by cyclodextrins (CDs) results in complexes with low stability. In the human organism, OTA exists mostly in the dianionic state (OTA(2-)). Therefore, our major goal was to develop a chemically modified cyclodextrin which gives a more stable complex with OTA than the previously published derivatives and which shows stronger preference towards OTA(2-). In our fluorescence spectroscopic study we demonstrate that quaternary ammonium beta-cyclodextrin (QABCD) fulfils both of these requirements. The calculated stability constant of the QABCD-OTA(2-) complex was 28,840 M(-1) (about 200-fold higher than that of the β-CD-OTA(2-) complex). We hypothesize, that QABCD may be a suitable tool for the decontamination of different OTA-contaminated drinks; furthermore, for alleviation of the toxic effects of OTA, such complex formation may reduce its absorption from the intestine.

  17. Late Quaternary environments, vegetation and agriculture in northern New Zealand

    NASA Astrophysics Data System (ADS)

    Horrocks, M.; Nichol, S. L.; Augustinus, P. C.; Barber, I. G.

    2007-03-01

    A sedimentological and plant microfossil history of the Late Quaternary is preserved in two sediment cores from early Polynesian ditch systems on southern Aupouri Peninsula. The study places human activities into a geomorphological and ecological context and allows comparison of natural and anthropogenic effects on two different geological settings: a floodplain and a relatively closed peat swamp. The data fill part of the current gap in the environmental record from northern New Zealand, namely MIS 3 (57k-26k yr BP). There is evidence for an increase in fire frequency in the region after 40k 14C yr BP, suggesting a shift to drier (and cooler) conditions. Pollen records show that conifer-hardwood forest dominated by podocarps (especially Dacrydium) prevailed prior to Polynesian arrival and deforestation within the last millennium, with Fuscopsora insignificant throughout. Both cores show sections with gaps in deposition or preservation, possible flood-stripping of peat during the pre-Holocene and mechanical disturbance by early Polynesians. The identification of prehistoric starch grains and other microremains of introduced Colocasia esculenta (taro) in both cores supports indirect evidence that the ditch systems of far northern New Zealand were used for the extensive cultivation of this crop. Copyright

  18. Epiguruk: a late Quaternary environmental record from northwestern Alaska

    USGS Publications Warehouse

    Hamilton, T.D.; Ashley, G.M.

    1993-01-01

    Epiguruk, a prominent bluff along the Kobuk River in northwestern Alaska, exposes a rich depositional record of Quaternary eolian and fluvial sand, with associated loess, paleosols, and periglacial features. Three major complexes of alluvial and eolian deposits are separated by two conspicuous organic-rich paleosols which formed during cool-moist interstadial intervals. Sediments between the two paleosols include eolian, channel, and floodplain deposits that formed during alluviation of the Kobuk River to a height of about 12m above the present level. The youngest depositional complex, which overlies the upper paleosol, is divisible into late Wisconsinan and Holocene components and into fluvial-channel, flood-plain, eolian-dune, sand-sheet, loess, and pond facies. Eolian sand from the active Kobuk sand sea overloaded the river during late Wisconsinan time, causing it to alluviate to about 13m above its modern level. The Holocene record reflects erosion and deposition by a small southern Tributary to the Kobuk River, downcutting by the Kobuk River toward its modern level, and subsequent erosion across a meander belt nearly 8km wide. 66 radiocarbon ages, many from rooted shrubs, provide a firm chronology for the past 35 k.y. at Epiguruk. -from Authors

  19. Quaternary ammonium disinfectants: microbial adaptation, degradation and ecology.

    PubMed

    Tezel, Ulas; Pavlostathis, Spyros G

    2015-06-01

    Disinfectants play an important role in maintaining acceptable health standards by significantly reducing microbial loads as well as reducing, if not eliminating, pathogens. This review focuses on quaternary ammonium compounds (QACs), a widely used class of organic disinfectants. Specifically, it reviews the occurrence, microbial adaptation, and degradation of QACs, focusing on recent reports on the ecology of QAC-degraders, the pathways and mechanisms of microbial adaptation which lead to resistance to QACs, as well as to antibiotics. With the help of culture-dependent and nonculture-dependent tools, as well as advanced analytical techniques, a better understanding of the fate and effect of QACs and their biotransformation products is emerging. Understanding the underlying mechanisms and conditions that result in QAC resistance and biodegradation will be instrumental in the prudent use of existing QAC formulations and foster the development of safer disinfectants. Development and implementation of (bio)technologies for the elimination of QACs from treated wastewater effluents will lessen adverse impacts to both humans and the environment.

  20. Summary of Quaternary geology of the Municipality of Anchorage, Alaska

    USGS Publications Warehouse

    Schmoll, H.R.; Yehle, L.A.; Updike, R.G.

    1999-01-01

    Quaternary geology of the Upper Cook Inlet region is dominated by deposits of glacier retreats that followed repeated advances from both adjacent and more distant mountains. At several levels high on the mountains, there are remnant glacial deposits and other features of middle or older Pleistocene age. Late Pleistocene lateral moraines along the Chugach Mountain front represent successively younger positions of ice retreat from the last glacial maximum. As the trunk glacier retreated northeastward up the Anchorage lowland, Cook Inlet transgressed the area, depositing the Bootlegger Cove Formation and Tudor Road deposits. The glacier then readvanced to form the latest Pleistocene Elmendorf Moraine, a prominent feature that trends across the Anchorage lowland. Extensive alluvium was deposited both concurrently and somewhat later as Cook Inlet regressed. Mountain valleys contain (1) locally preserved moraines possibly of early Holocene age; (2) poorly preserved moraine remnants of older late Holocene age; and (3) well-preserved moraines formed mainly during the Little Ice Age. Glaciers still occupy large parts of the mountains, the upper ends of some mountain valleys, and small cirques. Holocene landslide deposits, including those formed during the great Alaska earthquake of 1964, occur throughout the area, especially along bluffs containing the Bootlegger Cove Formation.

  1. Antibacterial nanocomposite with calcium phosphate and quaternary ammonium.

    PubMed

    Cheng, L; Weir, M D; Zhang, K; Xu, S M; Chen, Q; Zhou, X; Xu, H H K

    2012-05-01

    Secondary caries is a frequent reason for restoration failure, resulting from acidogenic bacteria and their biofilms. The objectives of this study were to: (1) develop a novel nanocomposite containing nanoparticles of amorphous calcium phosphate (NACP) and quaternary ammonium dimethacrylate (QADM); and (2) investigate its mechanical and antibacterial durability. A spray-drying technique yielded NACP with particle size of 116 nm. The nanocomposite contained NACP and reinforcement glass fillers, with QADM in the resin. Two commercial composites were tested as controls. Composites were inoculated with Streptococcus mutans. After 180-day water-aging, NACP+QADM nanocomposite had flexural strength and elastic modulus matching those of commercial controls (p > 0.1). NACP+QADM nanocomposite reduced the biofilm colony-forming units (CFU) by 3-fold, compared with commercial composites (p < 0.05). Metabolic activity and lactic acid production of biofilms on NACP+QADM were much less than those on commercial composites (p < 0.05). The antibacterial properties of NACP+QADM were maintained after water-aging for 30, 90, and 180 d (p > 0.05). In conclusion, the novel NACP-QADM nanocomposite greatly decreased biofilm metabolic activity, CFU, and lactic acid, while matching the load-bearing capability of commercial composites without antibacterial properties. The NACP-QADM nanocomposite with strong and durable antibacterial properties, together with its previously reported Ca-PO(4) release capability, may render it useful for caries-inhibiting restorations.

  2. Quaternary geology of the Rhode Island inner shelf

    USGS Publications Warehouse

    Needell, S. W.; O'Hara, C. J.; Knebel, H. J.

    1983-01-01

    Five sedimentary units and three erosional unconformities identified in high-resolution seismic-reflection profiles reveal the stratigraphic framework and Quaternary history of the inner continental shelf south of Narragansett Bay, Rhode Island. Late Tertiary to early Pleistocene rivers eroded the pre-Mesozoic bedrock and the Upper Cretaceous to lower Tertiary coastal plain and continental shelf strata to form a lowland and cuesta having a north-facing escarpment. The lowland and landward flanks of the cuesta were modified by glaciers during Pleistocene time and subsequently were overlain by drift and end moraine deposits of the late Wisconsinan ice advance. During deglaciation, freshwater lakes formed between the retreating ice and end moraines. Prior to sea-level rise, the drift and older deposits were cut by streams flowing south and southwestward toward Block Island Sound. As sea level rose, postglacial valleys were partly filled by fluvial, freshwater-peat, estuarine and salt-marsh deposits. Transgressing seas eroded the sea floor, exposing bedrock and coastal plain outcrops, and deposited marine sediments. ?? 1983.

  3. Adaptation of Aquatic Microbial Communities to Quaternary Ammonium Compounds

    PubMed Central

    Ventullo, Roy M.; Larson, Robert J.

    1986-01-01

    The effects of long-chain (C12 to C18) quaternary ammonium compounds (QACs) on the density, heterotrophic activity, and biodegradation capabilities of heterotrophic bacteria were examined in situ in a lake ecosystem. Monoalkyl and dialkyl substituted QACs were tested over a range of concentrations (0.001 to 10 mg/liter) in both acute (3 h) and chronic (21 day) exposures. In general, none of the QACs tested had significant adverse effects on bacterial densities in either acute or chronic studies. However, significant decreases in bacterial heterotrophic activity were noted in acute studies at QAC concentrations from 0.1 to 10 mg/liter. Chronic exposure of lake microbial communities to a specific monoalkyl QAC resulted in an adaptive response and recovery of heterotrophic activity. No-observable-effect level in the adapted populations was >10 mg/liter. Chronic exposure also resulted in significant increases in the number and activity of bacteria capable of biodegrading the material. The increase in biodegradation capability was observed at low (microgram per liter) concentrations which are approximately the same as realistic environmental levels. In general, our studies indicated that exposure of lake microbial communities to QACs results in the development of adapted communities which are less sensitive to potential toxic effects and more active in the biodegradation of these materials. PMID:16346991

  4. Cellulosomes: microbial nanomachines that display plasticity in quaternary structure.

    PubMed

    Gilbert, Harry J

    2007-03-01

    The assembly of proteins that display complementary activities into supramolecular intra- and extracellular complexes is central to cellular function. One such nanomachine of considerable biological and industrial significance is the plant cell wall degrading apparatus of anaerobic bacteria termed the cellulosome. The Clostridium thermocellum cellulosome assembles through the interaction of a type I dockerin module in the catalytic entities with one of several type I cohesin modules in the non-catalytic scaffolding protein. Recent structural studies have provided the molecular details of how dockerin-cohesin interactions mediate both cellulosome assembly and the retention of the protein complex on the bacterial cell surface. The type I dockerin, which displays near-perfect sequence and structural symmetry, interacts with its cohesin partner through a dual binding mode in which either the N- or C-terminal helix dominate heterodimer formation. The biological significance of this dual binding mode is discussed with respect to the plasticity of the orientation of the catalytic subunits within this supramolecular assembly. The flexibility in the quaternary structure of the cellulosome may reflect the challenges presented by the degradation of a heterogenous recalcitrant insoluble substrate by an intricate macromolecular complex, in which the essential synergy between the catalytic subunits is a key feature of cellulosome function.

  5. Possible Late Quaternary faulting in the Benton Hills, southeastern Missouri

    SciTech Connect

    Palmer, J.R.; Hoffman, D. . Dept. of Natural Resources)

    1993-03-01

    Geologic mapping in the 1930's by Dan Stewart and Lyle McManamy identified numerous faults in the Thebes Gap area of the Benton Hills, including two post-late Quaternary faults (max. of 10 m displacement) along the southeastern escarpment. Recent geologic mapping (Richard Harrison, pers. comm.) suggests dextral strike-slip displacement on most of these faults; some deformation post-dates the Pliocene-Pleistocene Mounds gravel. Small historical earthquake epicenters have been recorded in the Benton Hills area. Review of these data and analysis of the geologic and structural relationships to small- and large-scale drainage and alluvial features suggest tectonic control of the southeastern escarpment of the Benton Hills. The authors propose the coincidence of geologic structures and landforms resembles tectonically active alluvial basin margins, with the Benton Hills southeastern margin representing a fault block uplift escarpment. Future seismic reflection, drilling and trenching studies are planned to determine if the escarpment is fault controlled and of recent origin.

  6. Antibacterial Nanocomposite with Calcium Phosphate and Quaternary Ammonium

    PubMed Central

    Cheng, L.; Weir, M.D.; Zhang, K.; Xu, S.M.; Chen, Q.; Zhou, X.; Xu, H.H.K.

    2012-01-01

    Secondary caries is a frequent reason for restoration failure, resulting from acidogenic bacteria and their biofilms. The objectives of this study were to: (1) develop a novel nanocomposite containing nanoparticles of amorphous calcium phosphate (NACP) and quaternary ammonium dimethacrylate (QADM); and (2) investigate its mechanical and antibacterial durability. A spray-drying technique yielded NACP with particle size of 116 nm. The nanocomposite contained NACP and reinforcement glass fillers, with QADM in the resin. Two commercial composites were tested as controls. Composites were inoculated with Streptococcus mutans. After 180-day water-aging, NACP+QADM nanocomposite had flexural strength and elastic modulus matching those of commercial controls (p > 0.1). NACP+QADM nanocomposite reduced the biofilm colony-forming units (CFU) by 3-fold, compared with commercial composites (p < 0.05). Metabolic activity and lactic acid production of biofilms on NACP+QADM were much less than those on commercial composites (p < 0.05). The antibacterial properties of NACP+QADM were maintained after water-aging for 30, 90, and 180 d (p > 0.05). In conclusion, the novel NACP-QADM nanocomposite greatly decreased biofilm metabolic activity, CFU, and lactic acid, while matching the load-bearing capability of commercial composites without antibacterial properties. The NACP-QADM nanocomposite with strong and durable antibacterial properties, together with its previously reported Ca-PO4 release capability, may render it useful for caries-inhibiting restorations. PMID:22403412

  7. Quaternary ammonium sulfanilamide: a membrane-impermeant carbonic anhydrase inhibitor

    SciTech Connect

    Henry, R.P.

    1987-05-01

    A novel carbonic anhydrase (CA) inhibitor, quaternary ammonium sulfanilamide (QAS), was tested for potency as a CA inhibitor and for its ability to be excluded from permeating biological membranes. Inhibitor titration plots of QAS vs. pure bovine CA II and CA from the gills of the blue crab, Callinectes sapidus, yielded K/sub i/ values of approx. 15 ..mu..M; thus QAS is a relatively weak but effective CA inhibitor. Permeability of the QAS was directly tested by two independent methods. The inhibitor was excluded from human erythrocytes incubated in 5 mM QAS for 24 h as determined using an /sup 18/O-labeled mass spectrometer CA assay for intact cells. Also QAS injected into the hemolymph of C. sapidus (1 or 10 mM) did not cross the basal membrane of the gill. The compound was cleared from the hemolymph by 96 h after injection, and at no time during that period could the QAS be detected in homogenates of gill tissue. Total branchial CA activity was only slightly reduced following the QAS injection. These data indicate that QAS is a CA inhibitor to which biological membranes are impermeable and that can be used in vivo and in vitro in the study of membrane-associated CA.

  8. Quaternary ammonium sulfanilamide: a membrane-impermeant carbonic anhydrase inhibitor.

    PubMed

    Henry, R P

    1987-05-01

    A novel carbonic anhydrase (CA) inhibitor, quaternary ammonium sulfanilamide (QAS), was tested for potency as a CA inhibitor and for its ability to be excluded from permeating biological membranes. Inhibitor titration plots of QAS vs. pure bovine CA II and CA from the gills of the blue crab, Callinectes sapidus, yielded Ki values of approximately 15 microM; thus QAS is a relatively weak but effective CA inhibitor. Permeability of the QAS was directly tested by two independent methods. The inhibitor was excluded from human erythrocytes incubated in 5 mM QAS for 24 h as determined using an 18O-labeled mass spectrometer CA assay for intact cells. Also QAS injected into the hemolymph of C. sapidus (1 or 10 mM) did not cross the basal membrane of the gill. The compound was cleared from the hemolymph by 96 h after injection, and at no time during that period could the QAS be detected in homogenates of gill tissue. Total branchial CA activity was only slightly reduced following the QAS injection. These data indicate that QAS is a CA inhibitor to which biological membranes are impermeable and that can be used in vivo or in vitro in the study of membrane-associated CA.

  9. Ligand exchange in quaternary alloyed nanocrystals--a spectroscopic study.

    PubMed

    Gabka, Grzegorz; Bujak, Piotr; Giedyk, Kamila; Kotwica, Kamil; Ostrowski, Andrzej; Malinowska, Karolina; Lisowski, Wojciech; Sobczak, Janusz W; Pron, Adam

    2014-11-14

    Exchange of initial, predominantly stearate ligands for pyridine in the first step and butylamine (BA) or 11-mercaptoundecanoic acid (MUA) in the second one was studied for alloyed quaternary Cu-In-Zn-S nanocrystals. The NMR results enabled us to demonstrate, for the first time, direct binding of the pyridine labile ligand to the nanocrystal surface as evidenced by paramagnetic shifts of the three signals attributed to its protons to 7.58, 7.95 and 8.75 ppm. XPS investigations indicated, in turn, a significant change in the composition of the nanocrystal surface upon the exchange of initial ligands for pyridine, which being enriched in indium in the 'as prepared' form became enriched in zinc after pyridine binding. This finding indicated that the first step of ligand exchange had to involve the removal of the surface layer enriched in indium with simultaneous exposure of a new, zinc-enriched layer. In the second ligand exchange step (replacement of pyridine with BA or MUA) the changes in the nanocrystal surface compositions were much less significant. The presence of zinc in the nanocrystal surface layer turned out necessary for effective binding of pyridine as shown by a comparative study of ligand exchange in Cu-In-Zn-S, Ag-In-Zn-S and CuInS2, carried out by complementary XPS and NMR investigations.

  10. Causal link between Quaternary paleoclimatic changes and volcanic islands evolution

    NASA Astrophysics Data System (ADS)

    Quidelleur, X.; Hildenbrand, A.; Samper, A.

    2006-12-01

    High precision radiometric ages of large-volume volcanic flank collapses indicate a causal relationship between the evolution of volcanic islands from different geodynamic contexts and global climatic changes. We present a compilation of previously well-dated events within the last 1 Myr from Tahiti, Hawaii, Canary Islands, together with new ages from Guadeloupe and Martinique (Lesser Antilles). Ages of major flank collapses show a strong correlation with Quaternary climate changes evidenced by a global stack of benthic d18O records. Effectively, most collapses occurred within a glacial to interglacial termination. The ages reported here favor the hypothesis that for the last 900 kyr major flank collapse events occurred during the onset of glacial to interglacial transitions when a sudden influx of melt water from polar ice caps results in rapid sea level rise. Thus, it can be inferred that, when geological causes such as regional tectonics or edifice strength reduction due to volcanic processes are also present, rapid sea level rise can favor large mass wasting events. We propose that following a sub aerial erosion interval during low sea level stands, rapid sea level rise induces enhanced coastal erosion and sudden changes of pore pressure conditions within basal layers, which favor edifice failure. Since these events can trigger tsunamis and can initiate periods of increased volcanic activity, we show here that global warming may result in an increased likelihood of certain geologic hazards, such as large landslides of up to several hundreds cubic kilometers.

  11. Resistance to quaternary ammonium compounds in food-related bacteria.

    PubMed

    Sidhu, Maan Singh; Sørum, Henning; Holck, Askild

    2002-01-01

    Microbial resistance to antimicrobial agents continues to be a major problem. The frequent use and misuse of disinfectants based on quaternary ammonium compounds (QACs) in food-processing industries have imposed a selective pressure and may contribute to the emergence of disinfectant-resistant microorganisms. A total number of 1,325 Gram-negative isolates (Escherichia coli, other coliforms Vibrio spp., and Aeromonas spp.) and 500 Enterococcus spp. from food and food-processing industries and fish farming were screened for natural resistance to the QAC-based disinfectant benzalkonium chloride (BC). Of the 1,825 isolates, 16 strains, mainly from meat retail shops, showed low-level resistance to BC. None of the Enterococcus spp. from broiler, cattle, and pigs, the antibiotic-resistant E. coli from pig intestine and fish pathogens Vibrio spp. and Aeromonas spp. from the Norwegian fish farming industry were resistant to BC. The BC-resistant strains were examined for susceptibility to 15 different antibiotics, disinfectants, and dyes. No systematic cross-resistance between BC and any of the other antimicrobial agents tested was detected. Stable enhanced resistance in Enterobacter cloacae isolates was demonstrated by step-wise adaptation in increasing concentrations of BC. In conclusion, BC resistance among food-associated Gram-negative bacteria and Enterococcus spp. is not frequent, but resistance may develop to user concentrations after exposure to sublethal concentrations of BC. PMID:12523638

  12. All carbon nanotubes are not created equal

    SciTech Connect

    Geohegan, David B; Puretzky, Alexander A; Rouleau, Christopher M

    2010-01-01

    This chapter presents the various factors that enter into consideration when choosing the source of carbon nanotubes for a specific application. Carbon nanotubes are giant molecules made of pure carbon. They have captured the imagination of the scientific community by the unique structure that provides superior physical, chemical, and electrical properties. However, a surprisingly wide disparity exists between the intrinsic properties determined under ideal conditions and the properties that carbon nanotubes exhibit in real world situations. The lack of uniformity in carbon nanotube properties is likely to be the main obstacle holding back the development of carbon nanotube applications. This tutorial addresses the nonuniformity of carbon nanotube properties from the synthesis standpoint. This synthesis-related nonuniformity is on top of the intrinsic chirality distribution that gives the ~1:2 ratio of metallic to semiconducting nanotubes. From the standpoint of carbon bonding chemistry the variation in the quality and reproducibility of carbon nanotube materials is not unexpected. It is an intrinsic feature that is related to the metastability of carbon structures. The extent to which this effect is manifested in carbon nanotube formation is governed by the type and the kinetics of the carbon nanotube synthesis reaction. Addressing this variation is critical if nanotubes are to live up to the potential already demonstrated by their phenomenal physical properties.

  13. Setting the Time Frame - Investigating Culture-Environment Interactions in the Late Quaternary

    NASA Astrophysics Data System (ADS)

    Klasen, N.; Just, J.; Rethemeyer, J.

    2015-12-01

    We present a status update of luminescence age estimates of sediments from Ethiopia and the Iberian Peninsula that are related to human occupation and are currently being investigated in the interdisciplinary Collaborative Research Center "Our way to Europe - Culture-Environment Interaction and Human Mobility in the Late Quaternary" (CRC806). The aim of the project is to investigate the dispersal of anatomically modern humans from Africa to Europe, and a robust chronology is essential. In the CRC806, dating is provided by luminescence, palaeomagnetic and radiocarbon techniques. A key site of the CRC806 is Chew Bahir in Ethiopia. This lake basin is located in the source area of the emergence of anatomically modern humans. Radiocarbon, luminescence and palaeomagnetic dating have been used to develop an age-depth model for drill core sediments that date back to 115 ka over 42 m depth. The model is independent of palaeoclimatic proxy interpretation. On the Iberian Peninsula cave deposits have been dated with luminescence techniques and compared to radiocarbon ages wherever applicable. Recently, existing radiocarbon chronologies on the Iberian Peninsula have been revised in light of methodological developments. Robust luminescence dating is therefore especially important in this region, where the stratigraphy is difficult to constrain. We aim to improve the precision of luminescence age estimates by comparing different measurement techniques for equivalent dose and dose-rate determinations, and by using Bayesian statistics to develop age-depth models. Combining different chronological techniques has enabled the development of accurate and precise chronologies, which will allow a better understanding of the emergence of modern humans.

  14. Sanitizing in Dry-Processing Environments Using Isopropyl Alcohol Quaternary Ammonium Formula.

    PubMed

    Kane, Deborah M; Getty, Kelly J K; Mayer, Brian; Mazzotta, Alejandro

    2016-01-01

    Dry-processing environments are particularly challenging to clean and sanitize because introduced water can favor growth and establishment of pathogenic microorganisms such as Salmonella. Our objective was to determine the efficacy of an isopropyl alcohol quaternary ammonium (IPAQuat) formula for eliminating potential Salmonella contamination on food contact surfaces. Clean stainless steel coupons and conveyor belt materials used in dry-processing environments were spot inoculated in the center of coupons (5 by 5 cm) with a six-serotype composite of Salmonella (approximately 10 log CFU/ml), subjected to IPAQuat sanitizer treatments with exposure times of 30 s, 1 min, or 5 min, and then swabbed for enumeration of posttreatment survivors. A subset of inoculated surfaces was soiled with a breadcrumb-flour blend and allowed to sit on the laboratory bench for a minimum of 16 h before sanitation. Pretreatment Salmonella populations (inoculated controls, 0 s treatment) were approximately 7.0 log CFU/25 cm(2), and posttreatment survivors were 1.31, 0.72, and < 0.7 (detection limit) log CFU/25 cm(2) after sanitizer exposure for 30 s, 1 min, or 5 min, respectively, for both clean (no added soil) and soiled surfaces. Treatment with the IPAQuat formula using 30-s sanitizer exposures resulted in 5.68-log reductions, whereas >6.0-log reductions were observed for sanitizer exposures of 1 and 5 min. Because water is not introduced into the processing environment with this approach, the IPAQuat formula could have sanitation applications in dry-processing environments to eliminate potential contamination from Salmonella on food contact surfaces. PMID:26735036

  15. Montane climate and vegetation dynamics in easternmost Beringia during the Late Quaternary

    NASA Astrophysics Data System (ADS)

    Szeicz, J. M.; MacDonald, G. M.

    2001-01-01

    New and published palynological data are used to investigate the Quaternary vegetation history of high-elevation sites in the Mackenzie Mountains of easternmost Beringia (Northwest Territories, Canada). During some previous interglacials, sites that are presently treeless supported spruce forest, indicating conditions were warmer than present and possibly warmer than at any time in the Holocene. No information is available on vegetation in unglaciated portions of the Mountains during the Last Glacial Maximum, but in the Lateglacial (ca 12,000-10,000 14C yr BP), a shrub- and herb-dominated vegetation, characterized in the pollen record by Artemisia, Betula, Salix, gramnoids and herbs, grew at all elevations, and extended in a continuous corridor southwards to Alberta. Populus balsamifera probably grew up to and above present treeline between about 11,000 and 9000 yr BP. The late Pleistocene vegetation of the Mackenzie Mountains contrasts with the rest of eastern and central Beringia, which supported a Betula-dominated shrub tundra by 12,000 yr BP. Betula shrub tundra expanded at all elevations in the mountains by 10,000 yr BP, followed by the expansion of Picea glauca and Picea mariana forest at ca 8000 yr BP. There is evidence for limited elevational shifts in treeline during the Holocene. Picea population densities in the forest-tundra were probably greater than at present in the early and mid-Holocene. Vegetation changes in the Mackenzie Mountains during this time are consistent with increased summer insolation and temperatures during the early to mid-Holocene. Higher resolution analysis (decadal to century scale) of small lake basins at treeline in this region also provide evidence for a late Holocene increase in forest-tundra density and/or a treeline rise centered on 3000 yr BP. Slight warming at this time has been noted at sites in the southern Rocky Mountains, and provides evidence for century-scale climatic fluctuations superimposed on the longer

  16. Scientists Identify New Quaternary Materials for Solar Cell Absorbers (Fact Sheet), NREL Highlights, Science

    SciTech Connect

    Not Available

    2011-10-01

    Research provides insight for exploring use of earth-abundant quaternary semiconductors for large-scale solar cell applications. For large-scale solar electricity generation, it is critical to find new material that is Earth abundant and easily manufactured. Previous experimental studies suggest that Cu{sub 2}ZnSnS{sub 4} could be a strong candidate absorber materials for large-scale thin-film solar cells due to its optimal bandgap, high adsorption coefficient, and ease of synthesis. However, due to the complicated nature of the quaternary compound, it is unclear whether other quaternary compounds have physical properties suitable for solar cell application. Researchers at the National Renewable Energy Laboratory (NREL), Fudan University, and University College London have performed systematic searches of quaternary semiconductors using a sequential cation mutation method in which the material properties of the quaternary compounds can be derived and understood through the evolution from the binary, to ternary, and to quaternary compounds. The searches revealed that in addition to Cu{sub 2}ZnSnS{sub 4}, Cu{sub 2}ZnGeSe{sub 4} and Cu{sub 2}ZnSnSe{sub 4} are also suitable quaternary materials for solar cell absorbers. Through the extensive study of defect and alloy properties of these materials, the researchers propose that to maximize solar cell performance, growth of Cu{sub 2}ZnSnS{sub 4} under Cu-poor/Zn-rich conditions will be optimal and the formation of Cu{sub 2}ZnSn(S,Se){sub 4} alloy will be beneficial in improving solar cell performance.

  17. Mapping the late Quaternary evolution of the lower Mississippi Valley

    NASA Astrophysics Data System (ADS)

    Haugerud, R. A.; Simon, K. M.; James, T. S.

    2013-12-01

    The lower Mississippi Valley (LMV) extends from Cape Girardeau to Natchez and from Little Rock to Memphis. Extensive Quaternary terraces within the LMV have been considered to reflect downstream changes in base level (global sea level) and (or) upstream changes in water and sediment input because of glaciation. We suggest that the first-order control on terrace development was glacial-isostatic adjustment (GIA). Observed variation in heights of Quaternary alluvial surfaces at Memphis is 50 m (Rittenour et al., 2007). GIA modeling by Clark et al. (1994) predicted vertical displacement of as much as 130 m at Memphis over the last 18,000 years. ICE-5G models predict smaller displacement and reinforce the viability of GIA as the primary cause of LMV aggradation and incision. Existing analyses of LMV terraces are built on geomorphic maps by Saucier and colleagues (1974, 1994; Autin et al., 1991) that were interpreted from aerial photographs and inch-to-the-mile contour maps. Geomorphic mapping from high-resolution DEMs is more accurate, more rapid, and more reproducible than mapping from aerial photography and intermediate-resolution contours. Working from lidar DEMs (1-5 m XY resolution) and the 10 m National Elevation Dataset (NED) DEM largely derived from 1:24,000 scale contours, Haugerud is mapping the geomorphology of the LMV at ~1:500,000 scale. Goals are to explore the GIA-terrace hypothesis and improve the geomorphic and stratigraphic context for studies of New Madrid seismicity. Mapping leads to several observations: 1. The Holocene floodplain of the Mississippi River onlaps older surfaces. The river appears to be filling a hole created by collapse of the Laurentide forebulge. Continued filling of this accommodation space will, barring human intervention, enable the river to abandon its course through Thebes Gap in favor of a lower-elevation route through Oran Gap. 2. Within Holocene meander belts, younger levee crests are higher than older levee crests. The

  18. Quaternary tectonic setting of South-Central coastal California

    USGS Publications Warehouse

    Lettis, William R.; Hanson, Kathryn L.; Unruh, Jeffrey R.; McLaren, Marcia; Savage, William U.; Keller, Margaret A.

    2004-01-01

    Recent geodetic, geologic, and seismologic studies show that the south-central coast of California is a region of active Quaternary deformation. Northeast-directed crustal shortening is occurring in a triangular-shaped region between the Hosgri-San Simeon fault system on the west, the Southern Coast Ranges on the northeast, and the western Transverse Ranges on the south. We informally call this region the Los Osos domain. In this study, we conducted detailed geological, seismological, and geophysical investigations to characterize the nature and rates of deformation in the domain. Locations of active and potentially active faults and folds are compiled at a scale of 1:250,000 for the entire domain based primarily on onshore geologic data and offshore geophysical data. Crustal shortening in the domain is accommodated by a series of prominent northwest-trending reverse faults and localized folding. The reverse faults separate distinct structural blocks that have little or no internal deformation. Hangingwall blocks are being uplifted at rates of up to 0.2 mm/yr. Footwall blocks are either static or slowly subsiding at rates of 0.1 mm/yr or less, except for localized areas of concentrated subsidence directly adjacent to some faults. The cumulative rate of crustal shortening is about 1 to 2 mm/yr across the northern part of the domain based on observed geologic deformation. Cumulative shortening across the central and southern parts of the domain is poorly constrained by geologic data and may approach 2 to 3 mm/yr. Historical and instrumental seismicity generally are spatially associated with the uplifted blocks and bordering reverse faults to depths of about 10 km. Together with near-surface geological data and deeper crustal geophysical imaging that show high-angle faulting, the seismicity data indicate that the reverse faults probably extend to the base of the seismogenic crust. The base of the seismogenic crust may correspond with a mid-crustal detachment or

  19. Europe's Neogene and Quaternary lake gastropod diversity - a statistical approach

    NASA Astrophysics Data System (ADS)

    Neubauer, Thomas A.; Georgopoulou, Elisavet; Harzhauser, Mathias; Mandic, Oleg; Kroh, Andreas

    2014-05-01

    During the Neogene Europe's geodynamic history gave rise to several long-lived lakes with conspicuous endemic radiations. However, such lacustrine systems are rare today as well as in the past compared to the enormous numbers of "normal" lakes. Most extant European lakes are mainly results of the Ice Ages and are due to their (geologically) temporary nature largely confined to the Pleistocene-Holocene. As glacial lakes are also geographically restricted to glacial regions (and their catchment areas) their preservation potential is fairly low. Also deposits of streams, springs, and groundwater, which today are inhabited by species-rich gastropod assemblages, are rarely preserved. Thus, the pre-Quaternary lacustrine record is biased towards long-lived systems, such as the Late Miocene Lake Pannon, the Early to Middle Miocene Dinaride Lake System, the Middle Miocene Lake Steinheim and several others. All these systems have been studied for more than 150 years concerning their mollusk inventories and the taxonomic literature is formidable. However, apart from few general overviews precise studies on the γ-diversities of the post-Oligocene European lake systems and the shifting biodiversity in European freshwater systems through space and time are entirely missing. Even for the modern faunas, literature on large-scale freshwater gastropod diversity in extant lakes is scarce and lacks a statistical approach. Our preliminary data suggest fundamental differences between modern and pre-Pleistocene freshwater biogeography in central Europe. A rather homogenous central European Pleistocene and Holocene lake fauna is contrasted by considerable provincialism during the early Middle Miocene. Aside from the ancient Dessaretes lakes of the Balkan Peninsula, Holocene lake faunas are dominated by planorbids and lymnaeids in species numbers. This composition differs considerably from many Miocene and Pliocene lake faunas, which comprise pyrgulid-, hydrobiid-, viviparid-, melanopsid

  20. Equiatomic quaternary Heusler alloys: A material perspective for spintronic applications

    NASA Astrophysics Data System (ADS)

    Bainsla, Lakhan; Suresh, K. G.

    2016-09-01

    Half-metallic ferromagnetic (HMF) materials show high spin polarization and are therefore interesting to researchers due to their possible applications in spintronic devices. In these materials, while one spin sub band has a finite density of states at the Fermi level, the other sub band has a gap. Because of their high Curie temperature (TC) and tunable electronic structure, HMF Heusler alloys have a special importance among the HMF materials. Full Heusler alloys with the stoichiometric composition X2YZ (where X and Y are the transition metals and Z is a sp element) have the cubic L21 structure with four interpenetrating fcc sublattices. When each of these four fcc sublattices is occupied by different atoms (XX'YZ), a quaternary Heusler structure with different structural symmetries (space group F-43m, #216) is obtained. Recently, these equiatomic quaternary Heusler alloys (EQHAs) with 1:1:1:1 stoichiometry have attracted a lot of attention due to their superior magnetic and transport properties. A special class of HMF materials identified recently is known as spin gapless semiconductors (SGS). The difference in this case, compared with HMFs, is that the density of states for one spin band is just zero at the Fermi level, while the other has a gap as in the case of HMFs. Some of the reported SGS materials belong to EQHAs family. This review is dedicated to almost all reported materials belonging to EQHAs family. The electronic structure and hence the physical properties of Heusler alloys strongly depend on the degree of structural order and distribution of the atoms in the crystal lattice. A variety of experimental techniques has been used to probe the structural parameters and degree of order in these alloys. Their magnetic properties have been investigated using the conventional methods, while the spin polarization has been probed by point contact Andreev reflection technique. The experimentally obtained values of saturation magnetization are found to be in

  1. Permafrost-ice-sheet interactions during the Quaternary

    NASA Astrophysics Data System (ADS)

    Willeit, Matteo; Ganopolski, Andrey

    2016-04-01

    Permafrost influences a number of processes which are relevant for local and global climate. For example, it is well known that permafrost plays an important role in global carbon and methane cycles. Less is known about the interaction between permafrost and ice sheets. We recently included a permafrost module in the Earth system model CLIMBER-2 to explore the coupled Northern Hemisphere (NH) permafrost-ice-sheet evolution during the Quaternary. The model has been shown to perform generally well at reproducing present-day permafrost extent and thickness. Modelled permafrost extent at the Last Glacial Maximum (LGM) agrees well with reconstructions and previous modeling estimates. In a previous study we showed that over the last glacial cycle permafrost has a relatively modest impact on simulated NH ice sheet volume except at LGM, when including permafrost increases ice volume by about 15 m sea level equivalent in our model. This is explained by a delayed melting of the ice base from below by the geothermal heat flux when the ice sheet sits on a porous sediment layer and permafrost has to be melted first. Permafrost affects ice sheet dynamics only when ice extends over areas covered by thick sediments, which is the case at LGM. In transient model simulations of the "40 kyr world" of the early Pleistocene we show that when all continents are covered by a thick sediment layer the response of ice volume to the obliquity component of orbital forcing is enhanced while the response to precession is dampened. We therefore argue that permafrost could have played a role for ice sheet evolution when all continents were covered by a thick sediment layer, as was likely the case in the early Pleistocene before the sediment layer was gradually eroded by expanding ice sheets over parts of northern Canada and Scandinavia.

  2. Late Quaternary depositional history of the Albemarle Embayment, NC

    SciTech Connect

    Riggs, S.R.; Klingman, C.R.; Wyrick, R.A. . Dept. of Geology)

    1993-03-01

    The depositional history of Albemarle Embayment documents deep fluvial incisement by the Roanoke River system during glacial episodes and subsequent infilling by fluvial-estuarine-barrier island sediment sequences during interglacial transgressions. Unraveling the Holocene time slice will help reconstruct complex Quaternary records of multiple incisement and backfilling. A network of drill holes, vibracores, and seismic data suggest a four-phase infill history over the last 12,000 years. (1) Lower Roanoke River: (a) Bedload-charged, braided fluvial systems deposited basal sequences of sand and gravel prior to [approximately]5,000 BP. (b) Aggradational, swamp-forest floodplains developed [approximately]5,000 BP and bound the modern incised channels characterized by minimal bedload sedimentation. (2) Albemarle sound: (a) In the central basin, the basal channel sand sequence is overlain by an open estuarine, highly interlaminated sand and mud sequence that accumulated between [approximately]12,000 BP and [approximately]2,000 BP. (b) Depositional patterns within this unit suggest multiple oscillations of Holocene sea level that caused channel reincisement and subsequent backfilling. (c) Present estuarine marsh sedimentation began in protected coastal areas [approximately]5,000 BP. (3) Outer banks: (a) Barrier islands first influenced sedimentation in the area after [approximately]5,000 BP producing a semi-enclosed Albemarle Sound. (b) Deposition within the central basin shifted to uniform organic-rich muds that grade eastward into overwash and inlet sands. (4) Modern man: (a) colonial development within the drainage basins in the early 1700's AD produced a wedge of orange mud in inner Albemarle Sound. (b) Dam construction in the 1950's terminated orange mud deposition and the central basin reverted to organic-rich mud sedimentation.

  3. Regional quaternary submarine geomorphology in the Florida Keys

    USGS Publications Warehouse

    Lidz, B.H.; Reich, C.D.; Shinn, E.A.

    2003-01-01

    High-quality seismic reflection profiles fill a major gap in geophysical data along the south Florida shelf, allowing updated interpretations of the history of the Quaternary coral reef system. Incorporation of the new and existing data sets provides the basis for detailed color maps of the Pleistocene surface and thickness of overlying Holocene accretions. The maps cover the Florida Keys to a margin-wide upper-slope terrace (30 to 40 m deep) and extend from The Elbow Reef (north Key Largo) to Rebecca Shoal (Gulf of Mexico). The data indicate that Pleistocene bedrock is several meters deeper to the southwest than to the northeast, yet in general, Holocene sediments are ???3 to 4 m thick shelf-wide. The Pleistocene map demonstrates the significance of a westward-dipping bedrock surface to Holocene flooding history and coral reef evolution. Seismic facies show evidence for two possible Holocene stillstands. Aerial photographs provide information on the seabed surface, much of which is below seismic resolution. The photographs define a prominent, regional nearshore rock ledge that extends ???2.5 km seaward from the keys' shoreline. They show that bands of rock ridges exist along the outer shelf and on the upper-slope terrace. The photographs also reveal four tracts of outlier reefs on the terrace, one more than had been documented seismically. Seismic and photographic data indicate the tracts are >200 km long, nearly four times longer than previously thought. New interpretations provide insights into a youngest possible terrace age (ca. 175 ka?) and the likelihood that precise ages of oxygen isotope substage 5e oo??id tidal-bar and coral reef components may differ. The tidal-bar/reef complex forms the Florida Keys.

  4. Tetracalcium phosphate composite containing quaternary ammonium dimethacrylate with antibacterial properties.

    PubMed

    Cheng, Lei; Weir, Michael D; Limkangwalmongkol, Penwadee; Hack, Gary D; Xu, Hockin H K; Chen, Qianming; Zhou, Xuedong

    2012-04-01

    Tooth caries is a carbohydrate-modified bacterial infectious disease, and recurrent caries is a frequent reason for restoration failure. The objective of this study was to develop a novel antibacterial composite using tetracalcium phosphate (TTCP) fillers and bis(2-methacryloyloxy-ethyl) dimethyl-ammonium bromide, which is a quaternary ammonium dimethacrylate (QADM). QADM was synthesized using 2-(N,N-dimethylamino)ethyl methacrylate and 2-bromoethyl methacrylate and incorporated into a resin. The resin was filled with 40% TTCP and 30% glass particles. The following QADM mass fractions in the composite were tested: 0%, 6%, 12%, and 18%. Streptococcus mutans biofilms were formed on the composites and the colony-forming units (CFUs), metabolic activity, and lactic acid production were measured. The TTCP-QADM composite had flexural strength and elastic modulus similar to those of two commercial composites (p > 0.1). Increasing the QADM content in TTCP composite greatly decreased the bacteria growth and biofilm matrix production. There were significantly more dead bacteria with increasing QADM content. TTCP composite containing 18% QADM had biofilm CFU, metabolic activity, and acid production about half of those without QADM. Inversely linear relationships were established between QADM mass fraction and S. mutans biofilm CFU, metabolic activity, and acid production, with correlation coefficients R(2) ≥ 0.98. In conclusion, TTCP-QADM composites were developed and the effect of QADM mass fraction on the antibacterial properties of the composite was determined for the first time. The novel TTCP-QADM composites possessing a strong antibacterial capability, together with calcium phosphate ion release and good mechanical properties, are promising for dental restorations to reduce biofilm growth and recurrent caries.

  5. Tetracalcium phosphate composite containing quaternary ammonium dimethacrylate with antibacterial properties

    PubMed Central

    Cheng, Lei; Weir, Michael D.; Limkangwalmongkol, Penwadee; Hack, Gary D.; Xu, Hockin H. K.; Chen, Qianming; Zhou, Xuedong

    2012-01-01

    Tooth caries is a carbohydrate-modified bacterial infectious disease, and recurrent caries is a frequent reason for restoration failure. The objective of this study was to develop a novel antibacterial composite using tetracalcium phosphate (TTCP) fillers and bis(2-methacryloyloxy-ethyl) dimethyl-ammonium bromide, which is a quaternary ammonium dimethacrylate (QADM). QADM was synthesized using 2-(N,N-dimethylamino)ethyl methacrylate and 2-bromoethyl methacrylate and incorporated into a resin. The resin was filled with 40% TTCP and 30% glass particles. The following QADM mass fractions in the composite were tested: 0%, 6%, 12%, and 18%. Streptococcus mutans biofilms were formed on the composites and the colony-forming units (CFUs), metabolic activity, and lactic acid production were measured. The TTCP-QADM composite had flexural strength and elastic modulus similar to those of two commercial composites (p > 0.1). Increasing the QADM content in TTCP composite greatly decreased the bacteria growth and biofilm matrix production. There were significantly more dead bacteria with increasing QADM content. TTCP composite containing 18% QADM had biofilm CFU, metabolic activity, and acid production about half of those without QADM. Inversely linear relationships were established between QADM mass fraction and S. mutans biofilm CFU, metabolic activity, and acid production, with correlation coefficients R2 ≥ 0.98. In conclusion, TTCP-QADM composites were developed and the effect of QADM mass fraction on the antibacterial properties of the composite was determined for the first time. The novel TTCP-QADM composites possessing a strong antibacterial capability, together with calcium phosphate ion release and good mechanical properties, are promising for dental restorations to reduce biofilm growth and recurrent caries. PMID:22190356

  6. Distribution of the Late-Quaternary deformation in Northwestern Himalaya

    NASA Astrophysics Data System (ADS)

    Vassallo, R.; Mugnier, J.-L.; Vignon, V.; Malik, M. A.; Jayangondaperumal, R.; Srivastava, P.; Jouanne, F.; Carcaillet, J.

    2015-02-01

    Three main Cenozoic thrusts at the front of Northwestern Himalaya have accommodated most of the India-Eurasia convergence across the belt over the last million years and produced the present relief. Their recent tectonic activity is poorly known because of the long period of inaccessibility of the Jammu and Kashmir state, and because the latest and only large earthquake recorded in the region occurred in 1555 AD. We show where the deformation is localized during the Late-Quaternary, and determine shortening rates across the structures by analyzing the geometry and chronology of geomorphic markers. The Main Boundary Thrust in this region ceased moving at least ∼30 ka ago. On the contrary, the more external Medlicott-Wadia Thrust and Main Frontal Thrust, both merging at depth on the sub-flat detachment of the Main Himalayan Thrust, exhibit hectometric-scale deformations accumulated during the last thousands of years. The total shortening rate absorbed by these faults over the last 14-24 ka is between 13.2 and 27.2 mm/yr (11.2 ± 3.8 and 9.0 ± 3.2 mm /yr, respectively). Part of this deformation may be associated to the geometry of the Chenab reentrant, which could generate an extra oblique component. However, the lower bound of our shortening rates is consistent with previously determined geodetic rates. Active deformation on these structures follows an in-sequence/out-of-sequence pattern, with breaking of both ramps being possible for earthquakes triggered on the main detachment.

  7. Late Quaternary land-sea correlations, northern Labrador, Canada

    SciTech Connect

    Clark, P.; Josenhans, H.

    1985-01-01

    Late Quaternary glacial and postglacial units in the Torngat Mountains, northern Labrador, are correlated with units identified on the adjacent continental shelf. The late Wisconsinan Laurentide Ice Sheet drained through major valleys of the Torngat Mountains as outlet glaciers, depositing the Saglek Moraines. These are of regional extent and have been mapped from Saglek Fiord north to Noodleook Fiord. A C-14 date of 18,210 +/- 1900 BP on total organic matter (TOM) from lake sediment dammed by a segment of the Saglek Moraines is interpreted as a maximum date for deposition of the Saglek Moraine system because of possible contamination. Glacial sediments comprising the Saglek Moraines are correlated with upper till mapped in troughs and saddles on the continental shelf. Outlet glaciers depositing a late Wisconsinan unit flowed through Labrador fiords and onto the shelf at low basal shear stresses, particularly on the shelf where, although grounded, they were hydrostatically buoyed up and moved principally by sliding. A glaciomarine unit conformably overlies late Wisconsinan till on the shelf and on the land. This unit is a gravelly clayey silt, contains abundant foraminifera, and has up to 60% limestone in the pebble fraction. C-14 dates suggest deposition of this unit began ca. 10,000 BP on the shelf and 9000 BP on the land, an ended by 8000 BP. Limestone pebbles in this unit suggest a source in part from sediment-laden icebergs and pack-ice from the north. Marine deposition from ca. 8000-0 BP is characterize by basinal sedimentation.

  8. An Atlas of Submarine Glacial Landforms: Modern, Quaternary and Ancient

    NASA Astrophysics Data System (ADS)

    Jakobsson, M.; Dowdeswell, J. A.; Canals, M.; Todd, B. J.; Dowdeswell, E. K.; Hogan, K. A.

    2014-12-01

    In the past two decades there have been several advances that make the production of an atlas of submarine glacial landforms timely. First is the development of high-resolution imaging technologies; multi-beam echo-sounding or swath bathymetry that allows the detailed mapping of the sea floor at water depths of tens to thousands of metres across continental margins, and 3-D seismic methods that enable the visualisation of palaeo-continental shelves in Quaternary sediments and ancient palaeo-glacial rocks (e.g. Late Ordovician of Northern Africa). A second technological development is that of ice-breaking or ice-strengthened ships that can penetrate deep into the ice-infested waters of the Arctic and Antarctic, to deploy the multibeam systems. A third component is that of relevance - through both the recognition that the polar regions, and especially the Arctic, are particularly sensitive parts of the global environmental system and that these high-latitude margins (both modern and ancient) are likely to contain significant hydrocarbon resources. An enhanced understanding of the sediments and landforms of these fjord-shelf-slope systems is, therefore, of increasing importance to both academics and industry. We are editing an Atlas of Submarine Glacial Landforms that presents a series of individual contributions that describe, discuss and illustrate features on the high-latitude, glacier-influenced sea floor. Contributions are organised in two ways: first, by position on a continental margin - from fjords, through continental shelves to the continental slope and rise; secondly, by scale - as individual landforms and assemblages of landforms. A final section provides discussion of integrated fjord-shelf-slope systems. Over 100 contributions by scientists from many countries contain descriptions and interpretation of swath-bathymetric data from both Arctic and Antarctic margins and use 3D seismic data to investigate ancient glacial landforms. The Atlas will be

  9. Late Quaternary denudation, Death and Panamint Valleys, eastern California

    USGS Publications Warehouse

    Jayko, A.S.

    2005-01-01

    Late Quaternary denudation rates are constrained from alluvial fans and tributary watersheds in central Death and Panamint Valleys. Preliminary results suggest that the denudation rate is in part a function of the mean watershed elevation. Rainfall increases semi-logarithmically with higher elevation to about 2500 m where it becomes limited by the regional average maximum moisture content of the air mass. The fan volumes show a power-law relation to the watershed areas. The fan volumes ranged from about 250,000 to 4000 km3 and the watershed areas range from about 60,000 to 2000 km2. The upper limit of the denudation rates estimated from small Death Valley fans restricted to the east side of the basin along the Black Mountain frontal scarp range between about 0.03 to 0.18 mm/yr. The maximum is made by assuming most of the clastic accumulation in these fans followed the last highstand of Lake Manly around 24,000 yr which is the least conservative condition. The upper limit of the denudation rates from the Panamint fans range from 0.04 to 0.20 mm/yr assuming the accumulation mainly postdates OIS-4 ???60,000 yr or OIS-2 ???20,000 yr based on the presence or absence of inset shorelines from the last glacial-pluvial maximum. The greater denudation rate associated with the higher mean watershed elevations can mainly be attributed to the greater rainfall at higher elevation. Denudation rates are about a third or less of the Neogene dip-slip rates reported from nearby active faults consistent with relief increasing during dryer periods. ?? 2005 Elsevier B.V. All rights reserved.

  10. Late Quaternary Productivity Records from Coccolith Sr/Ca

    NASA Astrophysics Data System (ADS)

    Stoll, H. M.; Burke, A.; Mejia Ramirez, L. M.; Shimizu, N.; Ziveri, P. P. I.

    2014-12-01

    The Sr/Ca of coccoliths has been proposed as an indicator of productivity on the basis of correlation with export production in sediment traps and across upwelling productivity gradients, although the mechanism responsable for this relationship is not clear. For diverse oceanographic settings in the Late Quaternary, we compare coccolith Sr/Ca productivity records with those of other productivity indicators and proxies for mechanisms of productivity forcing. For the Somalia Basin in the Arabian Sea, coccolith Sr/Ca shows a large variation coherent with precessional forcing of wind strength as a mechanism for productivity regulation. During the glacial, the Sr/Ca peak is decoupled from productivity indicators based on organic C accumulation rate. For the Northern Bay of Bengal, coccolith Sr/Ca, Ba/Ti, and relative abundance of G. bulloides, all suggest greater productivity during the interglacial periods, consisted with Nd isotopic evidence for greater riverine nutrient inputs. In the Andaman Sea, coccolith Sr/Ca is highest during precessional maxima in the summer monsoon, consistent with proxies for chemical weathering in the Irawaddy rivershed. In the Eastern Mediterranean, coccolith Sr/Ca is on average low, and peaks during the E. Holocene interval characterized by deposition of sapropel S1. The peak in Sr/Ca however is comparable to the level maintained throughout the Holocene in the Western Mediterranean, where no sapropel occurs, implicating deepwater oxygen levels as a significant contributor to sapropel formation. Finally, on the Agulhas Bank, minima in coccolith Sr/Ca occur during obliquity minima which are periods of anomalous equatorward deposition of IRD in the Southern Ocean. Northward explansion of the westerly wind field during these cold intervals, block upwelling on the Agulhas Bank and result in low productivity.

  11. Quaternary Tectonism in a Collision Zone, Northwest Washington

    NASA Astrophysics Data System (ADS)

    McCrory, P. A.; Wolf, S. C.; Intelmann, S. S.; Danforth, W. W.; Weldon, R. J.; Blair, J. L.

    2004-12-01

    Kinematic, geodetic, and geologic observations define a region with 6-8 mm/y of north-south contraction between the Columbia River and Vancouver Island. We attribute this contraction to differential forearc-block motion within the Cascadia subduction system where the Oregon Coast Range block is moving northward relative to Vancouver Island. The contraction is accommodated by a combination of distributed uplift in the Olympic Mountains, and faulting along the margins of the Coast Range and Vancouver Island blocks. The tide gauge at Neah Bay, which records one of the highest rates of uplift anywhere along the Cascadia subduction margin, suggests that a significant portion of this north-south contraction occurs between the northern Olympic Peninsula and Vancouver Island. The northwest-trending Calawah fault, extending from Makah Bay eastward to near Lake Crescent, appears to mark the modern boundary between the Olympic Mountains block and the Vancouver Island block in northwestern Washington. Onshore, the 80+ km-long Calawah fault displaces late Quaternary glacial sediments and geodetic uplift rates increase abruptly across the fault zone. Offshore in Makah Bay, new multibeam, sidescan-sonar, and high-resolution seismic reflection data image a complex, multi-strand fault zone that offsets the seafloor and moves Cape Flattery rocks seaward. Two parallel, northwest-trending fault strands bound a down-dropped block that in turn terminates along a northward-trending anticlinal fold and thrust fault. These data suggest that the Calawah fault zone currently accommodates contraction both by uplift and by seaward translation of rocks north of the forearc-block boundary. Our geologic mapping in the Cape Flattery area indicates that differential block motion is accommodated by a combination of crustal uplift, folding, and left-lateral, strike-slip faulting.

  12. Can quaternary ammonium methacrylates inhibit matrix MMPs and cathepsins?

    PubMed Central

    Tezvergil-Mutluay, Arzu; Agee, Kelli A.; Mazzoni, Annalisa; Carvalho, Ricardo M.; Carrilho, Marcela; Tersariol, Ivarne L.; Nascimento, Fabio D.; Imazato, Satoshi; Tjäderhane, Leo; Breschi, Lorenzo; Tay, Franklin R; Pashley, David H.

    2014-01-01

    Objective Dentin matrices release ICTP and CTX fragments during collagen degradation. ICTP fragments are known to be produced by MMPs. CTX fragments are thought to come from cathepsin K activity. The purpose of this study was to determine if quaternary methacrylates (QAMs) can inhibit matrix MMPs and cathepsins. Methods Dentin beams were demineralizated, and dried to constant weight. Beams were incubated with rh-cathepsin B, K, L or S for 24 h at pH 7.4 to identify which cathepsins release CTX at neutral pH. Beams were dipped in ATA, an antimicrobial QAM to determine if it can inhibit dentin matrix proteases. Other beams were dipped in another QAM (MDPB) to determine if it produced similar inhibition of dentin proteases. Results Only beams incubated with cathepsin K lost more dry mass than the controls and released CTX. Dentin beams dipped in ATA and incubated for 1 week at pH 7.4, showed a concentration-dependent reduction in weight-loss. There was no change in ICTP release from control values, meaning that ATA did not inhibit MMPs. Media concentrations of CTX fell significantly at 15 wt% ATA indicating that ATA inhibits capthesins. Beams dipped in increasing concentrations of MDPB lost progressively less mass, showing that MDPB is a protease-inhibitor. ICTP released from controls or beams exposed to low concentrations were the same, while 5 or 10% MDPB significantly lowered ICTP production. CTX levels were strongly inhibited by 2.5–10% MDPB, indicating that MDPB is a potent inhibitor of both MMPs and cathepsin K. Significance CTX seems to be released from dentin matrix only by cathepsin K. MMPs and cathepsin K and B may all contribute to matrix degradation. PMID:25467953

  13. Quaternary deformation around the Palo Negro area, Pampa Norte, Argentina

    NASA Astrophysics Data System (ADS)

    Brunetto, E.; Iriondo, M.; Zamboni, L.; Gottardi, G.

    2010-04-01

    The Pampa Norte region is a great plain characterized by low slopes and accumulation of hundreds of meters of thick loose sediments. A high morphostructure denominated San Guillermo block stands out in the central plain, the Tostado-Selva scarp forming its western boundary. It is located in an intraplate setting characterized by low tectonic activity. However recent uplift can be inferred by means of terrain analysis and the sedimentology of the Palo Negro Fm. Pond deposits (Palo Negro Fm.) observed in the scarp suggest topographic inversion during the Late Quaternary in the Palo Negro area. The morphology indicates that the deformation was widely distributed, forming a gentle (ca. 5 m amplitude and 13 km wavelength) asymmetric fold. Low sinuosity lineaments located in the base of the scarp, coincident with knick points in the topographic profile, can be interpreted as the projection of tip-lines by high-angle fault-propagation. This geometry is compatible with reverse kinematics on blind faults. A deformation style with reactivation of pre-existing faults is consistent with structural observations. Seismic reflectors suggest the presence of Cretaceous high-angle normal faults, and the orientation of lineaments is similar to the orientation of the graben systems and transverse accommodation zones originated during the opening of the South Atlantic Ocean. One OSL dating of 67.4 ± 5.1 kyr B.P (from Palo Negro Fm. supposed as deposited on a flat plain floor) and a height difference of 9.5 m measured in the Tostado-Selva scarp account for an averaged uplift rate of 0.14 mm/year.

  14. Ultra-low-power carbon nanotube FET-based quaternary logic gates

    NASA Astrophysics Data System (ADS)

    Sharifi, Fazel; Moaiyeri, Mohammad Hossein; Navi, Keivan; Bagherzadeh, Nader

    2016-09-01

    This paper presents low-power carbon nanotube field-effect transistor (CNTFET)-based quaternary logic circuits. The proposed quaternary circuits are designed based on the CNTFET unique properties, such as the same carrier mobility for N- and P-type devices and also providing desirable threshold voltages by adopting proper diameters for the nanotubes. In addition, no paths exist between supply and ground rails in the steady states of the proposed designs, which eliminates the ON state static current and also the stacking technique is utilised in order to significantly reduce the leakage currents. The results of the simulations, conducted using Synopsys HSPICE with the standard 32 nm CNTFET technology, confirm the significantly lower power consumption, higher energy efficiency and lower sensitivity to process variation of the proposed designs compared to the state-of-the-art quaternary logic circuits. The proposed quaternary logic circuits have on average 92, 99 and 91% less total power, static power and PDP, respectively, compared with the most low-power and energy-efficient CNTFET-based quaternary logic circuits, recently presented in the literature.

  15. Mineralogical characteristics of the superlarge Quaternary bauxite deposits in Jingxi and Debao counties, western Guangxi, China

    NASA Astrophysics Data System (ADS)

    Liu, Xuefei; Wang, Qingfei; Zhang, Qizuan; Feng, Yuewen; Cai, Shuhui

    2012-06-01

    In recent decades, more than 0.5 billion tons of ores scattered in the Quaternary laterite in western Guangxi, China have been explored. The ores were derived from a bauxite horizon in Permian via physical break-up and re-sediment process. Utilizing various test methods, i.e., XRD, DTA, TG/DTG, SEM/EDS and EPMA, the mineralogical characteristics of the Quaternary bauxite ores in Jingxi and Debao counties were investigated. XRD was used together with TG/DTG to obtain relatively accurate ore mineral abundance. Diaspore is the major phase, whereas hematite, kaolinite, anatase, chamosite, gibbsite, goethite, illite and rutile are minor. Diaspore is characterized by a small particle size, low degrees of crystallinity and complex chemical composition. Both gibbsite and goethite have a varied particle size, and goethite crystals contain high Al substitution and Si. It is clarified that diaspore, chamosite and anatase were formed in a mildly reduced and alkaline depositional environment in Permian, while gibbsite, hematite, goethite and part kaolinite were precipitated from Al3+-, Si4+- and Fe3+-enriched solutions within an Quaternary oxidized environment. The ions Al3+, Si4+ and Fe3+ are mostly released from chamosite in its dissolution process. The different physicochemical conditions between the Permian depositional and the Quaternary weathering periods resulted in a complex mineral assemblage in the Quaternary bauxite.

  16. Quaternary extensional growth folding beneath Reno, Nevada, imaged by urban seismic profiling

    USGS Publications Warehouse

    Stephenson, William J.; Frary, Roxy N.; Louie, John; Odum, Jackson K.

    2013-01-01

    We characterize shallow subsurface faulting and basin structure along a transect through heavily urbanized Reno, Nevada, with high‐resolution seismic reflection imaging. The 6.8 km of P‐wave data image the subsurface to approximately 800 m depth and delineate two subbasins and basin uplift that are consistent with structure previously inferred from gravity modeling in this region of the northern Walker Lane. We interpret two primary faults that bound the uplift and deform Quaternary deposits. The dip of Quaternary and Tertiary strata in the western subbasin increases with greater depth to the east, suggesting recurrent fault motion across the westernmost of these faults. Deformation in the Quaternary section of the western subbasin is likely evidence of extensional growth folding at the edge of the Truckee River through Reno. This deformation is north of, and on trend with, previously mapped Quaternary fault strands of the Mt. Rose fault zone. In addition to corroborating the existence of previously inferred intrabasin structure, these data provide evidence for an active extensional Quaternary fault at a previously unknown location within the Truckee Meadows basin that furthers our understanding of both the seismotectonic framework and earthquake hazards in this urbanized region.

  17. Structural Modifications to Quaternary Ammonium Polymer Coagulants to Inhibit N-Nitrosamine Formation.

    PubMed

    Zeng, Teng; Li, Russell Jingxian; Mitch, William A

    2016-05-01

    Quaternary ammonium cationic polymers, such as poly(diallyldimethylammonium chloride) (polyDADMAC) and epichlorohydrin-dimethylamine (Epi-DMA), are commonly used by water utilities to enhance removal of particles and dissolved organic matter (DOM) from raw waters. Unfortunately, chloramination of waters treated with quaternary ammonium polymers leads to the formation of carcinogenic N-nitrosodimethylamine (NDMA). In this study, two approaches were developed to modify polyDADMAC and Epi-DMA to inhibit N-nitrosamine formation. The first approach involved treatment of polymers with methyl iodide (MeI), an alkylating agent, to convert polymer-bound tertiary amine groups to less chloramine-reactive quaternary ammonium groups. The second approach involved synthesis of polymers bearing less chloramine-reactive quaternary ammonium groups with dipropylamino (DPA) substituents. Treatment with MeI reduced NDMA formation from polymers by ∼75%, while synthesis of DPA-based polymers eliminated NDMA formation and formed N-nitrosodipropylamine, which is 10-fold less carcinogenic than NDMA, at 20-fold lower yields. Bench-scale jar tests demonstrated that both MeI-treated and DPA-based polymers achieved similar removal of particles and DOM as the original polyDADMAC and Epi-DMA at both low and high doses, but formed significantly less N-nitrosamines. This work demonstrates two approaches for modifying quaternary ammonium cationic polymers, which may enable water utilities to meet potential future regulations on N-nitrosamines while maintaining polymer usage to meet existing regulations. PMID:27096602

  18. Atomic-scale properties of Ni-based FCC ternary, and quaternary alloys

    SciTech Connect

    Tamm, Artur; Aabloo, Alvo; Klintenberg, Mattias; Stocks, Malcolm; Caro, Alfredo

    2015-08-26

    The aim of our study is to characterize some atomic-scale properties of Ni-based FCC multicomponent alloys. For this purpose, we use Monte Carlo method combined with density functional theory calculations to study short-range order (SRO), atomic displacements, electronic density of states, and magnetic moments in equimolar ternary NiCrCo, and quaternary NiCrCoFe alloys. The salient features for the ternary alloy are a negative SRO parameter between Ni Cr and a positive between Cr Cr pairs as well as a weakly magnetic state. For the quaternary alloy we predict negative SRO parameter for Ni Cr and Ni Fe pairs and positive for Cr Cr and Fe Fe pairs. Atomic displacements for both ternary and quaternary alloys are negligible. In contrast to the ternary, the quaternary alloy shows a complex magnetic structure. The electronic structure of the ternary and quaternary alloys shows differences near the Fermi energy between a random solid solution and the predicted structure with SRO. Despite that, the calculated EXAFS spectra does not show enough contrast to discriminate between random and ordered structures. Finally, the predicted SRO has an impact on point-defect energetics, electron phonon coupling and thermodynamic functions and thus, SRO should not be neglected when studying properties of these two alloys.

  19. Atomic-scale properties of Ni-based FCC ternary, and quaternary alloys

    DOE PAGES

    Tamm, Artur; Aabloo, Alvo; Klintenberg, Mattias; Stocks, Malcolm; Caro, Alfredo

    2015-08-26

    The aim of our study is to characterize some atomic-scale properties of Ni-based FCC multicomponent alloys. For this purpose, we use Monte Carlo method combined with density functional theory calculations to study short-range order (SRO), atomic displacements, electronic density of states, and magnetic moments in equimolar ternary NiCrCo, and quaternary NiCrCoFe alloys. The salient features for the ternary alloy are a negative SRO parameter between Ni Cr and a positive between Cr Cr pairs as well as a weakly magnetic state. For the quaternary alloy we predict negative SRO parameter for Ni Cr and Ni Fe pairs and positive formore » Cr Cr and Fe Fe pairs. Atomic displacements for both ternary and quaternary alloys are negligible. In contrast to the ternary, the quaternary alloy shows a complex magnetic structure. The electronic structure of the ternary and quaternary alloys shows differences near the Fermi energy between a random solid solution and the predicted structure with SRO. Despite that, the calculated EXAFS spectra does not show enough contrast to discriminate between random and ordered structures. Finally, the predicted SRO has an impact on point-defect energetics, electron phonon coupling and thermodynamic functions and thus, SRO should not be neglected when studying properties of these two alloys.« less

  20. Heterogeneous receptor binding of classical quaternary muscarinic antagonists. I. Bovine tissue distribution.

    PubMed

    Roffel, A F; Ensing, K; in 't Hout, W G; de Zeeuw, R A; Zaagsma, J

    1991-01-01

    In competition experiments with the tertiary radioligand [3H]dexetimide, classical quaternary muscarinic antagonists like ipratropium bromide and N-methylscopolamine bromide distinguished two muscarinic binding sites in bovine brain (total brain minus cerebellum) membranes, in contrast to their tertiary analogues, atropine and scopolamine, which recognized only one binding site. This binding behavior was found to be almost identical in bovine striatal membranes, both in terms of binding affinities and proportions of high (Q1) and low (Q2) affinity binding sites. Both in total brain and in striatal membranes, the Q1/Q2 binding heterogeneity was independent of pirenzepine binding heterogeneity (M1/M2). In peripheral tissues, the binding properties of quaternary muscarinic antagonists varied. Whereas tertiary as well as quaternary compounds showed only high affinity binding towards muscarinic receptors in bovine atrial and left ventricular membranes, heterogeneous binding behavior was observed with quaternary but not with tertiary antagonists in bovine tracheal smooth muscle membranes. The tissue distribution found in the present study suggests that bovine tracheal smooth muscle contraction studies might shed light on the functional significance of the anomalous binding behavior of quaternary muscarinic antagonists. PMID:1824191

  1. Compilation of known and suspected Quaternary faults within 100 km of Yucca Mountain, Nevada and California

    SciTech Connect

    Piety, L.A.

    1996-12-31

    Geologic data have been compiled for known and suspected Quaternary faults in southern Nevada and southeastern California within about 100 km of the potential repository site at Yucca Mountain. The data set includes regional studies that attempt to identify and evaluate lineaments, scraps, and other possible tectonic landforms of possible Quaternary age, detailed studies that focus on a single fault, and geologic studies that were completed for purposes other than evaluation of Quaternary fault activity. Studies included in this compilation are those that were available as of December 1993. Faults that have known or suspected Quaternary activity are presented on a topographic base map at a scale of 1:250,000. Data for each fault that are pertinent to the assessment of future faulting and earthquake events are assembled on description sheets and summarized on tables. This compilation identifies ten faults within 50 km of the site but outside the site area and an additional fourteen faults between 50 km and 100 km of the site for which evidence for Holocene or late Pleistocene surface rupture has been reported in the literature. The longest and most continuous of these faults is the northwest-striking, 250-km-long Furnace Creek fault (including its possible extension into Fish Lake Valley), which is located about 50 km west of the site. In addition to identifying known or suspected Quaternary faults within about 100 km of the site, this compilation demonstrates the lack of information for most of these faults.

  2. Neogene and Quaternary history of vegetation, climate, and plant diversity in Amazonia

    NASA Astrophysics Data System (ADS)

    van der Hammen, Thomas; Hooghiemstra, Henry

    2000-04-01

    The neotropical Amazonian and Andean plant diversity developed mainly during the Tertiary. In Amazonia, Miocene floral diversity seems considerably higher than today. During the Neogene, tropical taxa entered newly created montane area, and montane taxa entered the tropical lowlands. The general decrease of temperature during the upper Neogene and especially during the Quaternary glacial periods may have caused considerable extinctions in the lowlands. Representation of pollen of apparently principally montane taxa ( Podocarpus, Hedyosmum) in Miocene, Pliocene, and Quaternary sediments of Amazonia and surroundings, is still difficult to interpret in terms of temperature decrease at low elevation. Changes in precipitation may have profound impact on the composition of vegetation communities; Ilex and Melastomataceae increase significantly in many glacial pollen records. Increase of Weinmannia in Amazonian pollen records seems the best indicator of downward migration of montane vegetation belts. A temperature lowering at sea-level of 4.5 ±1°C during the Last Glacial Maximum (LGM) seems reasonable; it may have caused a downslope migration of some 700 m of the lower montane vegetation belt; lower montane arboreal species may have been able to grow in higher elevation areas (>500 m) of Amazonia, increasing background pollen values of montane taxa in the area. Difference between a cool and wet Middle Pleniglacial (60-28 ka BP), and a cold and dry Upper Pleniglacial (28-14 ka BP; thus including the LGM) is evident in Andean and Amazonian records; statements about environmental conditions of the ice-age Amazon should be specified chronologically. The Middle Pleniglacial is a time of accumulation of fluvial sediments. The Upper Pleniglacial is a time of incision of the rivers in their sediments; sedimentation started again in the Lateglacial (since ca. 13 ka BP) and the Holocene, when lake levels rose again. Based on simplified considerations of precipitation changes and

  3. Efficient method of starch functionalization to bis-quaternary structure unit.

    PubMed

    Chauhan, Kalpana; Kaur, Jasvinder; Kumari, Ankita; Kumari, Anita; Chauhan, G S

    2015-09-01

    This paper presents the synthesis of bis-quaternary starch by innocuous reagents. For this, starch was functionalized to di-aldehyde structure by periodate oxidation. Aldehyde is reactive and amenable to further derivatization to amine structure. It was functionalized to amine via the modified Leuckart-Wallach reaction. Then, the aminated starch was modified to the quaternary form by the exhaustive methylation. The structural characterization of synthesized compounds was performed using titrimetric analytical estimation, FTIR, (1)H NMR, (13)C NMR, and SEM-EDX. Analytical results showed 58.8% aldehyde content in di-aldehyde starch. The synthesized quaternary derivatives with gemini like structure showed high degree of quaternization 62%. In conclusion, the applied protocol is efficient and revealed high extent of modification with almost good uniformity from the characterization studies.

  4. Synthesis and characterization of chitosan based dye containing quaternary ammonium group.

    PubMed

    Tang, Ruilin; Zhang, Ying; Zhang, Yang; Yu, Zhiming

    2016-03-30

    A new antimicrobial biopolymer dye was synthesized by reaction of quaternary ammonium salt of chitosan and reactive red x-3b. And quaternary ammonium salt of chitosan was produced by grafting glycidyltrimethylammonium chloride on chitosan. The synthesized materials were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), solubility test and antimicrobial test. Results show that the antimicrobial biopolymer dye was combined by N(+)(CH3)3 of quaternary ammonium salt of chitosan and sulfonic group of reactive red x-3b. Water solubility of chitosan biopolymer dye was increased as well as pH value. In addition, antibacterial property of new synthesized dye was excellent, whose antibacterial rates of Staphylococcus and Escherichia coli were both bigger than 99%. These results may provide new perspectives on improving the decorative properties and antimicrobial properties in wood industry.

  5. Magnetic Properties of Quaternary Deposits, Kenai Peninsula, Alaska -- Implications for Aeromagnetic Anomalies of Upper Cook Inlet

    USGS Publications Warehouse

    Saltus, R.W.; Haeussler, P.J.

    2004-01-01

    We measured magnetic susceptibilities of exposed Quaternary deposits on several beach cliffs and river banks on the Kenai Peninsula near Soldotna, Alaska. Data, descriptions, and photos from nine sites are included in this report. The mean susceptibility for Quaternary materials in this region is approximately 2.5 x 10-3 SI units. This is sufficiently magnetic to produce subtle aeromagnetic anomalies such as those observed to correlate with topographic features in the region of the measurements. The highest susceptibilities measured (greater than 20 x 10-3 SI units) may help, at least in part, to explain moderate amplitude aeromagnetic anomalies observed elsewhere in Cook Inlet, particularly those relating to structures showing Quaternary movement. Comparison of measured beach cliff susceptibility and susceptibility predicted from idealized formulas and two-dimensional cliff models suggests that measured susceptibilies underestimate true bulk susceptibility by 20 percent to 50 percent in this region.

  6. Am(III) and Eu(III) extraction by aliquat.336 and benzyl substituted quaternary ammonium salts from nitrate and thiocyanate solutions

    SciTech Connect

    Chiarizia, R.; Gatrone, R.C.; Horwitz, E.P.

    1995-07-01

    The extraction of Am(III) and Eu(III) from HNO{sub 3} - LiNO{sub 3} or from HCOOH-NH{sub 4}SCN solutions by different quaternary ammonium salts dissolved in o-xylene was investigated as function of the aqueous phase composition. As extractants, the nitrate or thiocyanate salts of Aliquat.336, tridodecylmethylammonium, benzyl-dimethyldodecylammonium, p-methoxybenzyldimethyldodecylammonium and p-trifluoromethylbenzyldimethyldodecylammonium were used. The extraction data obtained with the thiocyanate- formic acid aqueous solutions were quantitatively interpreted by a reaction scheme that takes into account the aqueous metal complexation and the competition of formic acid and metal species for the extractant reaction center. The effect of the benzyl group (whether substituted or not) on the metal and acid extraction by the different quaternary ammonium salts was interpreted on the basis of the inductive effect of the substituents. In the thiocyanate system, Aliquat.336 provided the highest Am/Eu separation factors. 24 refs., 10 figs., 2 tabs.

  7. Geomorphic assessment of late Quaternary volcanism in the Yucca Mountain area, southern Nevada: Implications for the proposed high-level radioactive waste repository

    SciTech Connect

    Wells, S.G.; McFadden, L.D.; Renault, C.E.; Crowe, B.M.

    1991-03-01

    Volcanic hazard studies for high-level radioactive waste isolation in the Yucca Mountain area, Nevada, require a detailed understanding of Quaternary volcanism to forecast rates of volcanic processes. Recent studies of the Quaternary Cima volcanic fields in southern California have demonstrated that K-Ar dates of volcanic landforms are consistent with their geomorphic and pedologic properties. The systematic change of these properties with time may be used to provide age estimates of undated or questionably dated volcanic features. The reliability of radiometric age determinations of the youngest volcanic center, Lathrop Wells, near the proposed Yucca Mountain site in Nevada has been problematic. In this study, a comparison of morphometric, pedogenic, and stratigraphic data establishes that correlation of geomorphic and soil properties between the Cima volcanic field and the Yucca Mountain area is valid. Comparison of the Lathrop Wells cinder cone to a 15-20 ka cinder cone in California shows that their geomorphic-pedogenic properties are similar and implies that the two cones are of similar age. The authors of ca. 0.27 Ma for the latest volcanic activity at Lathrop Wells, approximately 20 km from the proposed repository, may be in error by as much as an order of magnitude and that the most recent volcanic activity is no older than 20 ka.

  8. Geomorphic assessment of late Quaternary volcanism in the Yucca Mountain area, southern Nevada: Implications for the proposed high-level radioactive waste repository

    NASA Astrophysics Data System (ADS)

    Wells, S. G.; McFadden, L. D.; Renault, C. E.; Crowe, B. M.

    1990-06-01

    Volcanic hazard studies for high-level radioactive waste isolation in the Yucca Mountain area, Nevada, require a detailed understanding of Quaternary volcanism to forecast rates of volcanic processes. Recent studies of the Quaternary Cima volcanic field in southern California have demonstrated that K-Ar dates of volcanic landforms are consistent with their geomorphic and pedologic properties. The systematic change of these properties with time may be used to provide age estimates of undated or questionably dated volcanic features. The reliability off radiometric age determinations of the youngest volcanic center, Lathrop Wells, near the proposed Yucca Mountain site in Nevada has been problematic. In this study, a comparison of morphometric, pedogenic, and stratigraphic data establishes that correlation of geomorphic and soil properties between the Cima volcanic field and the Yucca Mountain area is valid. Comparison of the Lathrop Wells cinder cone to a 15-20 ka cinder cone in California shows that their geomorphic-pedogenic properties are similar and implies that the two cones are of similar age. We conclude that previous determinations of ca. 0.27 Ma for the latest volcanic activity at Lathrop Wells, approximately 20 km from the proposed repository, may be in error by as much as an order of magnitude and that the most recent volcanic activity is no older than 20 ka.

  9. Analysis of a Global Database on Quaternary Explosive Volcanism

    NASA Astrophysics Data System (ADS)

    Ortiz, N.; Sparks, R. S.; Hobbs, L.

    2009-12-01

    Large volcanic eruptions, despite their low frequency of occurrence, have the potential to cause massive loss of life and affect the health of humans and animals and cause major economic losses. The knowledge of the evolution of past volcanic processes is key to mitigate the effects of future eruptions. Field studies along with application of diverse techniques of analysis generate volcanic data, such as, eruption ages, petrological classification, estimates of ejected volume, intensity and magnitude. The design of databases on volcano data constitutes a tool for experts in charge of identifying places at risk, forecasting volcano activity, and scientists interested in finding the relation between volcanic eruptions and climate change. A global database on Quaternary explosive on explosive volcanism has been developed as part of the VOGRIPA project and implemented which main aim is to facilitate accessing data on volcanic eruptions for the scientific community. An explosive eruption is included in the database if its magnitude is 4 or above and if it has been dated. Also at least one measure of the eruption magnitude, such as erupted mass, erupted volume or Volcano Explosivity Index (VEI) is required. The use of the age data is examined for periods of time according to the nature of the age data and also considering major Earth events such as glaciations and interglacials. As we go back in the time, peaks in volcanic activity most likely reflect biases of data; however is an increase in the number of explosive eruptions in the 7th to 10th century and in the past 650 years in the global database on explosive volcanism as well as ice core records. Statistical analyses are applied to eruption records to test the linked hypothesis that the volcanism has been constant over the time interval chosen and that there is not under-recording. The hypothesis is in agreement for the period between 15,000 and 45,000 years BP, and for the whole period including only eruptions with

  10. Ternary and quaternary oxides of Bi, Sr, and Cu

    NASA Technical Reports Server (NTRS)

    Casais, M. T.; Millan, P.; Rasines, I.; Campa, J. A.

    1990-01-01

    Before the discovery of superconductivity in an oxide of Bi, Sr, and Cu, the system Bi-Sr-Cu-O had not been studied, although several solid phases had been identified in the two-component regions of the ternary system Bi2O3-SrO-CuO. The oxides Sr2CuO3, SrCu2O2, SrCuO2, and Bi2CuO4 were then well known and characterized, and the phase diagram of the binary system Bi2O3 -SrO had been established in the temperature range 620 to 1000 C. Besides nine solutions of compositions Bi(2-2x) Sr(x) O(3-2x) and different symmetries, this diagram includes three definite compounds of stoichiometries Bi(2)SrO4, Bi2Sr2O5, and Bi2Sr3O6 (x = 0.50, 0.67 and 0.75 respectively), only the second of which with known unit-cell of orthorhombic symmetry, dimensions (A) a = 14.293(2), b = 7.651(2), c = 6.172(1), and z = 4. The first superconducting oxide in the system Bi-Sr-Cu-O was initially formulated as Bi2Sr2Cu2O(7+x), with an orthorhombic unit-cell of parameters (A) a = 5.32, b = 26.6, c = 48.8. In a preliminary study the same oxide was formulated with half the copper content, Bi(2)Sr(2)CuO(6+x), and indexed its reflections assuming an orthorhombic unit-cell of dimensions (A) a = 5.390(2), b = 26.973(8), c = 24.69(4). Subsequent studies by diffraction techniques have confirmed the composition 2:2:1. A new family of oxygen-deficient perovskites, was characterized, after identifying by x ray diffraction the phases present in the products of thermal treatments of about 150 mixtures of analytical grade Bi2O3, Sr(OH)2-8H2O and CuO at different molar ratios. X ray diffraction data are presented for some other oxides of Bi and Sr, as well as for various quaternary oxides, among them an oxide of Bi, Sr, and Cu.

  11. Unexpected climatic impacts of orbital forcing out of the Quaternary

    NASA Astrophysics Data System (ADS)

    Ramstein, Gilles; Zhang, Zhongshi; Le Hir, Guillaume; Contoux, Camille; Donnadieu, Yannick; Dumas, Christophe; Schuster, Mathieu; Li, Camille

    2016-04-01

    For Quaternary, the impact of orbital variations on climate is huge and well documented. Especially, during the last million years, drastic climate changes occurred, consisting in transitions from glacial to interglacial periods driven by changes in 65°N summer insolation with 100 kyears periodicity. Nevertheless, the imprint of so-called Milankovic forcings has also been found for Tertiary and Secondary, as for instance during mid-Cretaceous period (Herbert et al., Nature, 1986, Giorgioni et al, Paleoceanography, 2012) or during Devonian period (De Vleeschouwer et al, EPSL, 2013). For both periods, the climatic imprints of orbital forcings are recorded in a warm world without ice sheet. Here, we show through simulation studies the large impact of orbital forcing in very different geological contexts, pointing out the important role of Milankovic cycle throughout Earth history. The first and most striking result depicts the role of insolation changes during the melting of the Marinoan snowball [635 Ma] (Benn et al, Nature Geoscience 2015). This is one of the oldest imprints of orbital forcing on climate. Our result solved a long lasting controversy concerning the melting of the last snowball episode between a huge deglaciation at very high CO2 level and data showing glacial/interglacial cycles occurring during that melting. Our modelling studies focusing on Svalbard high resolution records (Benn et al, Nature Geoscience 2015) demonstrate that the glacial/fluvial oscillation was related to orbital forcing in a context of very high CO2 level. Much more recently, during the Tortonian period [11-7 Ma], the orbital cycles shaped the environment and drove the hominin dispersal in Africa. During Tortonian, the ultimate shrinkage of a huge epicontinental sea, that extended from Eastern Europe to Western Asia, has been shown to produce major changes on Asian monsoon (Ramstein et al, Nature, 1997) and triggered the onset of Sahara desert (Zhang et al, Nature 2014). Moreover

  12. Late Quaternary rates of stream incision in Northeast Peloponnese, Greece

    NASA Astrophysics Data System (ADS)

    Karymbalis, Efthimios; Papanastassiou, Dimitrios; Gaki-Papanastassiou, Kalliopi; Ferentinou, Maria; Chalkias, Christos

    2016-09-01

    This study focuses on defining rates of fluvial incision for the last 580±5 kyr along valley systems of eight streams that drain the eastern part of the northern Peloponnese. The streams are developed on the uplifted block of the offshore-running Xylokastro normal fault, one of the main faults bounding the southern edge of the Gulf of Corinth half-graben, and have incised a set of ten uplifted marine terraces having an amphitheatric shape. These terraces range in age from 60±5 kyr to 580±5 kyr and have been mapped in detail and correlated with late Pleistocene oxygen-isotope stages of high sea-level stands by previous studies. The terraces were used in this paper as reference surfaces in order to define fluvial incision rates at the lower reaches of the studied streams. To evaluate incision rates, thirty-three topographic valley cross-sections were drawn using fieldwork measurements as well as using a highly accurate (2×2 cell size) Digital Elevation Model (DEM) at specific locations where streams cut down the inner edges of the marine terraces. For each cross-section the ratio of valley floor width to valley height (Vf) and long-term mean stream incision rates were estimated for the last 580±5 kyr, while rock uplift rates were estimated for the last 330±5 kyr. The geomorphic evolution of the valleys on the uplifted block of the Xylokastro fault has been mainly driven by the lithology of the bedrock, sea level fluctuations during the late Quaternary, and incision of the channels due to the tectonic uplift. Stream incision rates range from 0.10±0.1 mm/yr for the last 123±7 kyr to 1.14±0.1 mm/yr for the last 310±5 kyr and are gradually greater from east to west depending on the distance from the trace of the fault. Downcutting rates are comparable with the rock uplift rates, which range from 0.4±0.02 mm/yr to 1.49±0.12 mm/yr, over the last 330±5 kyr.

  13. Ternary and quaternary oxides of Bi, Sr and Cu

    NASA Technical Reports Server (NTRS)

    Casais, M. T.; Millan, P.; Rasines, I.; Campa, J. A.

    1991-01-01

    Before the discovery of superconductivity in an oxide of Bi, Sr, and Cu, the system Bi-Sr-Cu-O had not been studied, although several solid phases had been identified in the two-component regions of the ternary system Bi2O3-Si-O-CuO. The oxides Sr2CuO3, SrCu2O2, SrCuO2, and Bi2CuO4 were then well known and characterized, and the phase diagram of the binary system Bi2O3-SrO had been established in the temperature range 620 to 1000 C. Besides nine solutions of compositions Bi(2-2x) Sr(x) O(3-2x) and different symmetries, this diagram includes three definite compounds of stoichiometries Bi(2)BrO4. Bi2Sr2O5, and Bi2Sr3O6 (x - 0.50, 0.67 and 0.75 respectively), only the second of which with known unit-cell of orthorhombic symmetry, dimensions (A) a = 14.293(2), b = 7.651(2), c = 6.172(1), and z = 4. The first superconducting oxide in the system Bi-Sr-Cu-O was initially formulated as Bi2Sr2Cu2O(7+x), with an orthorhombic unit-cell of parameters (A) a = 5.32, b = 26.6, c = 48.8. In a preliminary study the same oxide was formulated with half the copper content, Bi(2)Sr(2)CuO(6+x), and index its reflections assuming an orthorhombic unit-cell of dimensions (A) a = 5.390(2), b = 26.973(8), c = 24.69(4). Subsequent studies by diffraction techniques have confirmed the composition 2:2:1. A new family of oxygen-deficient perovskites, was characterized, after identifying by x ray diffraction the phases present in the products of thermal treatments of about 150 mixtures of analytical grade Bi2O3, Sr(OH)2-8H2O and CuO at different molar ratios. X ray diffraction data are presented for some other oxides of Bi and Sr, as well as for various quaternary oxides, among them an oxide of Bi, Sr, and Cu.

  14. A New Quaternary Strand of the Karakoram Fault System, Ladakh Himalayas

    NASA Astrophysics Data System (ADS)

    Bohon, W.; Hodges, K.; Arrowsmith, R.; Tripathy, A.

    2009-12-01

    The NW-SE striking, dextral Karakoram fault system stretches for more than 1200 km from the Pamirs of Central Asia at least as far southeast as the Kailas area of Tibet. Estimates for the total lateral displacement along the fault system range from 150-1000 km, and estimated Quaternary rates of slip range from 1 to 30 mm/yr. In the Ladakh region of NW India (~ 33°28’N, 78°45’E), the fault system expresses as northern and southern strands bounding the Pangong Range. Studies of ductile deformation fabrics along these strands suggest that slip began in the Miocene, and Brown et al. (2002) documented Quaternary right-lateral slip along the northern strand at ~4 mm/yr on the basis of offset geomorphic features. The lack of documented Quaternary offset along the southern strand has led most researchers to assume that Quaternary slip on the Karakoram fault system in this region was partitioned exclusively to the northern strand. Our summer 2009 field work in the Pangong Range and adjacent Nubra Valley provides the first documentation of significant Quaternary activity along the southern strand. In the valley between the villages of Tangste (34°01’ N, 78°10’ E) and Durbuk (34°06’ N, 78°07’), the fault is visible high on the northeastern mountain side as a break in slope with offset Quaternary paleosurfaces and beheaded and offset stream channels, the largest of which have been displaced by as much as 250 m. Field mapping north of Durbuk, near the town of Tangyar (34°15’N, 77°52’E), shows that the southern strand continues northwest and cuts across the landscape as a sinuous, continuous trace with shutter ridges, offset alluvial fan surfaces, and sag ponds developed along its length. In this region, the northern and southern strands are linked by a Quaternary, E-directed thrust fault that places high-grade metamorphic rocks over poorly consolidated Quaternary alluvium. The partitioning of dextral slip between two strands of the Karakoram system

  15. Quaternary cocrystals: combinatorial synthetic strategies based on long-range synthon Aufbau modules (LSAM)

    PubMed Central

    Dubey, Ritesh; Mir, Niyaz A.; Desiraju, Gautam R.

    2016-01-01

    A synthetic strategy is outlined whereby a binary cocrystal may be developed in turn into a ternary and finally into a quaternary cocrystal. The strategy hinges on the concept of the long-range synthon Aufbau module (LSAM) which is a large supramolecular synthon containing more than one type of intermolecular interaction. Modulation of these interactions may be possible with the use of additional molecular components so that higher level cocrystals are produced. We report six quaternary cocrystals here. All are obtained as nearly exclusive crystallization products when four appropriate solid compounds are taken together in solution for crystallization. PMID:27006773

  16. Quaternary Tectonic and Climatic Processes shaping the Central Andean hyperarid forearc (southern Peru)

    NASA Astrophysics Data System (ADS)

    Audin, Laurence; Benavente, Carlos; Zerathe, Swann; Saillard, Marianne; Hall, Sarah R.; Farber, Daniel L.

    2015-04-01

    Understanding the forearc structure and processes related to Quaternary evolution and uplift of the Western Andean Cordillera remains an outstanding scientific issue. Models of Andean Plateau evolution based on Tertiary volcanic stratigraphy since 5Ma suggest that the deformation was focused along the eastern margin of the plateau and that minimal uplift occurred along the Pacific margin. On the contrary, new tectonic data and Quaternary surface 10Be dating highlight the presence of recently active deformation, incision and alluvial processes within the upper Andean forearc together with a regional uplift of the coastal zone. Additionally, the high obliquity observed in the northern Arica Bend region makes it an ideal target to discuss whether partitioning of the oblique convergence is accommodated by the neotectonic features that dissect the Quaternary forearc. Our goals are both to decipher the Quaternary tectonic and climatic processes shaping the hyperarid forearc along strike and across strike. Finally, we aim to quantify the respective influence of these factors in the overall uplift of the Western Andes. Indeed, sequences of pediment surfaces, landslide products, paleolake deposits and marine terraces found along the oblique Peruvian margin are a unique set of datable markers that can be used to quantify the rates of Quaternary processes. In this study, we focus on the southern Peru hyperarid Atacama area where regional surfaces and tectonic markers (scarps, folds, temporary streams and paleolake levels offsets…) are well preserved for the Quaternary timescale. Numerous landsliding events align on the major fault segments and reflect Plio-Pleistocene climatic and tectonic activity together with filled and strath terraces. As the present day sea-level is one of the highest levels recorded for Quaternary time span, any emerged marine terrace is preserved by tectonic coastal uplift. In particular, the geomorphic and chronologic correlation between marine and

  17. Volcanic processes recorded by inclusions in sanidine megacrystals ejected from Quaternary Rockeskyll volcano, Eifel, Germany

    NASA Astrophysics Data System (ADS)

    Eilhard, Nicole; Schreuer, Jürgen; Stöckhert, Bernhard

    2016-04-01

    Sanidine megacrystals were ejected by a late stage explosive eruption at the Quaternary Rockeskyll volcanic complex, Eifel volcanic field, Germany. The homogeneous distribution of barium (about 1 % wt BaO equivalent to about 2 mole % celsian component) indicates that the nearly perfect single crystals must have crystallized in the Ostwald-Miers range from a huge reservoir, probably in the roof of a magma chamber. Irregularities during crystal growth caused trapping of hydrous melt inclusions, which are the objective of the present study. The inclusions show a characteristic concentric microstructure, in the following described from the sanidine host towards the inclusion center: (1) Ba is enriched by a factor of 2 to 3 in a ca. 0.01 mm wide rim, compared to the otherwise homogeneous sanidine host; (2) inwards, the continuous rim is overgrown by a thin crust of Ba enriched sanidine with irregular surface; (3) a layer of glass with a composition similar to sanidine; (4) a second, thinner layer of glass slightly reduced in Na2O and K2O, separated from the first glass layer by a sharp interface with approximately spherical shape; (5) a bubble containing a fluid phase, composed of H2O and minor CO2. This record is interpreted as follows: After crystallization of the sanidine megacrystals, a rise in temperature within the magmatic system caused some re-melting of the Ba-rich sanidine around the inclusions. Partitioning of Ba between the small included melt reservoir and the host caused formation of the Ba-rich rim (layer 1) by diffusive exchange. The onset of cooling lead to crystallization of the thin sanidine crust (layer 2). Finally, very rapid decompression and cooling during the subsequent explosive eruption caused sequential phase separation (two stages) in the remaining melt, the denser melt phase (layers 3 and 4) quenched to glass, the complementary low-density volatile-rich phase forming the central bubble. In summary, the microstructure and phase composition of

  18. Primary alkaline magmas associated with the Quaternary Alligator Lake volcanic complex, Yukon Territory, Canada

    NASA Astrophysics Data System (ADS)

    Eiché, G. E.; Francis, D. M.; Ludden, J. N.

    1987-02-01

    The Alligator Lake complex is a Quaternary alkaline volcanic center located in the southern Yukon Territory of Canada. It comprises two cinder cones which cap a shield consisting of five distinct lava units of basaltic composition. Units 2 and 3 of this shield are primitive olivine-phyric lavas (13.5 19.5 cation % Mg) which host abundant spinel lherzolite xenoliths, megacrysts, and granitoid fragments. Although the two lava types have erupted coevally from adjacent vents and are petrographically similar, they are chemically distinct. Unit 2 lavas have considerably higher abundances of LREE, LILE, and Fe, but lower HREE, Y, Ca, Si, and Al relative to unit 3 lavas. The 87Sr/86Sr and 143Nd/144Nd isotopic ratios of these two units are, however, indistinguishable. The differences between these two lava types cannot be explained in terms of low pressure olivine fractionation, and the low concentrations of Sr, Nb, P, and Ti in the granitoid xenoliths relative to the primitive lavas discounts differential crustal contamination. The abundance of spinel lherzolite xenoliths and the high Mg contents in the lavas of both units indicates that their compositional differences originated in the upper mantle. The Al and Si systematics of these lavas suggests that, compared to unit 3 magmas, the unit 2 magmas may have segregated at greater depths from a garnet lherzolite mantle. The identical isotopic composition and similar ratios of highly incompatible elements in these two lava units argues against their differences being a consequence of random metasomatism or mantle heterogeneity. The lower Y and HREE contents but higher concentrations of incompatible elements in the unit 2 lavas relative to unit 3 can be most simply explained by differential partial melting of similar garnet-bearing sources. The unit 2 magmas thus appear to have been generated by smaller degrees of melting at a greater depth than the unit 3 magmas. The contemporaneous eruption of two distinct but

  19. Late Quaternary Megafaunal Extinctions in Northern Eurasia: Latest Results

    NASA Astrophysics Data System (ADS)

    Stuart, Anthony

    2010-05-01

    Anthony J. Stuart1 & Adrian M. Lister2 1 Biological and Biomedical Sciences, Durham University, South Road, Durham DH1 3LE, UK. Email: tony.s@megafauna.org.uk 2 Department of Palaeontology, The Natural History Museum, Cromwell Road, London SW7 5BD, UK. Email: a.lister@nhm.ac.uk. The global extinction of many spectacular species of megafauna (large terrestrial mammals, together with a few large reptiles and birds) within the last c. 50,000 years (Late Quaternary) has been attributed on the one hand to ‘overkill' by human hunters and on the other to environmental change. However, in spite of more than half a century of active interest and research the issue remains unresolved, largely because there are insufficient dated records of megafaunal species for most parts of the world. Northern Eurasia is an especially fruitful region in which to research megafaunal extinctions as it has a wealth of megafaunal material and crucially most extinctions occurred well within the range of radiocarbon dating. Our approach, in a series of projects over the last decade funded by the UK Natural Environment Research Council (NERC), involves amassing radiocarbon dates made directly on megafaunal material from across the entire region: a) by submitting a substantial number of samples (so far c. 500 dates) for AMS dating at Oxford (ORAU); b) obtaining AMS dates from colleagues working on aDNA projects; and c) carefully screening (‘auditing') dates from the literature. The dates (calibrated using OxCal) are plotted as time-sliced maps and as chronological/geographical charts. In our previous work we targeted a range of extinct species from Northern Eurasia: woolly mammoth, woolly rhinoceros, giant deer, cave bear (in collaboration with Martina Pacher), cave lion, and spotted hyaena (which survives today only in Sub-Saharan Africa). By this means we have established a reliable chronology for these extinctions which we are able to compare with the climatic, vegetational and

  20. Paleoclimatic Comparisons Between Three Late Quaternary Amazonian Lacustrine Records

    NASA Astrophysics Data System (ADS)

    Cordeiro, R. C.; Martins, G. S.; Fontes, D.; Turcq, B.; Sifeddine, A.; Seoane, J. S.; Conceição, M. G.; Barbosa, M.; Rodrigues, R. A.; Moreira, L.

    2012-12-01

    In recent years many records made in the cores of ice has shown significant changes in temperature associated with changes in atmospheric composition. The most notable changes occur between the glacials and interglacials cycles. Climatic changes in tropical areas during the global climatic changes is highly debatable. Even today, there are many controversies about the extent of the occurrence of dry weather in the Amazon during glacial periods. In the region of São Gabriel da Cachoeira, polynic diagram of Lagoa da Pata showed that vegetation remained with elements of forest trees, with replacement of elements of cold weather during the last glacial. In Carajás were observed substitution forest to savannah, during the last glacial. We present here a comparison of organic and inorganic geochemical sediment record of tree distinct Amazonian sectors: Morro dos Seis Lagos (AM) is located at 0°17‧9.68″ N and 66°40‧36.18″ W (Lagoa da Pata, LPT V core position) located in the forested upper Rio Negro basin in humid climate area (~3000 mm/yr), Carajás Region at 5°50‧ to 6°35‧ S and 49°30‧ to 52°00‧ situated 800 m high in lateritic crust in south eastern Amazonia (1800mm/yr) and São Benedito Region (PA) at 9°7'0.87"S and 56°16'0.00"W (Lago do Saci, Sac01/05 core position) in south Amazonia with a mean precipitation as Carajás around 1800 mm/yr. A comparison of these records reveals important changes in the environmental history of the Amazonian hydrological regime during the late Quaternary. The results of geochemical analyses reveal three hydrological and climatic regimes from 50,000 cal yr BP until the present. The first phase, between 50,000 until ~25,000 cal yr BP, was characterized by relatively high lake level as suggested by high organic carbon values in Lagoa da Pata and Carajás principally in the beginning of the period. In Saci Lake in the beginning of the record (35,500 cal yr BP) high values of TOC were observed relatively to last

  1. Late Quaternary high resolution sequence stratigraphy of an active rift, the Sperchios Basin, Greece: An analogue for subtle stratigraphic plays

    SciTech Connect

    Eliet, P.P.; Gawthorpe, R.L.

    1996-12-31

    The Sperchios Basin is an active asymmetric graben, bounded to the south by a major border fault system with major fault segments typically 20-30 km long. The basin is dominated by a major axial fluvio-deltaic system which enters the partially enclosed Maliakos Gulf to the east. Lateral sourced depositional systems within the basin comprise hanging-wall and footwall-derived alluvial fans and a narrow coastal plain along the footwall scarp bordering the Maliakos Gulf. High resolution seismic data from the Maliakos Gulf reveals three late Quaternary progradational parasequences sourced from axial and lateral depositional systems, with a regional late-Pleistocene transgressive surface dated at circa. 10 ka BP within the Maliakos Gulf. Differential subsidence of the late Pleistocene transgressive surface indicates marked variation in subsidence from 2.4 m ka{sup -1} at fault segment centers to 0.8 m ka{sup -1} at segment boundaries. The geometry and internal variability of each parasequence is controlled by the interplay of the local accommodation development and fluctuations in sediment supply and climatic conditions. The Sperchios Rift provides a modem analogue for subtle stratigraphic plays within ancient extensional basins. The study of controls on sediment source and transport patterns within active rifts has refined our appreciation of the controls on potential reservoir distribution and geometries.

  2. Late Quaternary high resolution sequence stratigraphy of an active rift, the Sperchios Basin, Greece: An analogue for subtle stratigraphic plays

    SciTech Connect

    Eliet, P.P. ); Gawthorpe, R.L. )

    1996-01-01

    The Sperchios Basin is an active asymmetric graben, bounded to the south by a major border fault system with major fault segments typically 20-30 km long. The basin is dominated by a major axial fluvio-deltaic system which enters the partially enclosed Maliakos Gulf to the east. Lateral sourced depositional systems within the basin comprise hanging-wall and footwall-derived alluvial fans and a narrow coastal plain along the footwall scarp bordering the Maliakos Gulf. High resolution seismic data from the Maliakos Gulf reveals three late Quaternary progradational parasequences sourced from axial and lateral depositional systems, with a regional late-Pleistocene transgressive surface dated at circa. 10 ka BP within the Maliakos Gulf. Differential subsidence of the late Pleistocene transgressive surface indicates marked variation in subsidence from 2.4 m ka[sup -1] at fault segment centers to 0.8 m ka[sup -1] at segment boundaries. The geometry and internal variability of each parasequence is controlled by the interplay of the local accommodation development and fluctuations in sediment supply and climatic conditions. The Sperchios Rift provides a modem analogue for subtle stratigraphic plays within ancient extensional basins. The study of controls on sediment source and transport patterns within active rifts has refined our appreciation of the controls on potential reservoir distribution and geometries.

  3. QuaBingo: A Prediction System for Protein Quaternary Structure Attributes Using Block Composition.

    PubMed

    Tung, Chi-Hua; Chen, Chi-Wei; Guo, Ren-Chao; Ng, Hui-Fuang; Chu, Yen-Wei

    2016-01-01

    Background. Quaternary structures of proteins are closely relevant to gene regulation, signal transduction, and many other biological functions of proteins. In the current study, a new method based on protein-conserved motif composition in block format for feature extraction is proposed, which is termed block composition. Results. The protein quaternary assembly states prediction system which combines blocks with functional domain composition, called QuaBingo, is constructed by three layers of classifiers that can categorize quaternary structural attributes of monomer, homooligomer, and heterooligomer. The building of the first layer classifier uses support vector machines (SVM) based on blocks and functional domains of proteins, and the second layer SVM was utilized to process the outputs of the first layer. Finally, the result is determined by the Random Forest of the third layer. We compared the effectiveness of the combination of block composition, functional domain composition, and pseudoamino acid composition of the model. In the 11 kinds of functional protein families, QuaBingo is 23% of Matthews Correlation Coefficient (MCC) higher than the existing prediction system. The results also revealed the biological characterization of the top five block compositions. Conclusions. QuaBingo provides better predictive ability for predicting the quaternary structural attributes of proteins. PMID:27610389

  4. Stereodefined Acyclic Polysubstituted Silyl Ketene Aminals: Asymmetric Formation of Aldol Products with Quaternary Carbon Stereocenters.

    PubMed

    Nairoukh, Zackaria; Marek, Ilan

    2015-11-23

    The regio- and stereoselective formation of stereodefined polysubstituted silyl ketene aminals is easily achieved through selective combined carbometalation-oxidation-silylation reactions. These substrates are ideal candidates for Mukaiyama aldol reactions with aliphatic aldehydes as they give the aldol products with a quaternary carbon stereocenter α to the carbonyl groups in outstanding diastereoselectivities. PMID:26448575

  5. Quaternary tectonic movements in the Argentine Puna, 24/sup 0/ to 27/sup 0/ s latitude

    SciTech Connect

    Strecker, M.R.; Alonso, R.; Rivelli, F.; Mon, R.

    1985-01-01

    The Puna of NW Argentina, one of the highest plateaus in the world, is the southern continuation of the Andean Altiplano geomorphic province of Peru and Bolivia. The region is not seismically active and reports of neotectonic movements are scarce. However, the areas of Salar de los Pastos Grandes, Salar del Hombre Muerto and Sierra Calalaste clearly have experienced Quaternary tectonic movements. At Salar de los Pastos Grandes, early Pleistocene lake sediments are offset by reverse faulting. At Salar del Hombre Muerto, Quaternary pyroclastic and debris-flow deposits are unconformable over sediments 5.86 m.y. old that were folded during the Pliocene-Pleistocene Diaguita deformation. Within the Quaternary sediments two separate deformational phases with reverse faulting and shallow thrusting are recognized. The timing of movement is well defined since the deformed strata are covered by a basalt flow 0.75 m.y. old. The flow in turn is affected by normal faulting. Similar normal faults associated with basalt flows were found at Sierra Calalaste. These observations are in accord with pronounced extensional movements and basaltic volcanism at the Calama-Olacapato-Toro Lineament (0.2 m.y. old flows) and might document the Quaternary transition from a compressive to an extensional tectonic regime in the southern Puna.

  6. QuaBingo: A Prediction System for Protein Quaternary Structure Attributes Using Block Composition.

    PubMed

    Tung, Chi-Hua; Chen, Chi-Wei; Guo, Ren-Chao; Ng, Hui-Fuang; Chu, Yen-Wei

    2016-01-01

    Background. Quaternary structures of proteins are closely relevant to gene regulation, signal transduction, and many other biological functions of proteins. In the current study, a new method based on protein-conserved motif composition in block format for feature extraction is proposed, which is termed block composition. Results. The protein quaternary assembly states prediction system which combines blocks with functional domain composition, called QuaBingo, is constructed by three layers of classifiers that can categorize quaternary structural attributes of monomer, homooligomer, and heterooligomer. The building of the first layer classifier uses support vector machines (SVM) based on blocks and functional domains of proteins, and the second layer SVM was utilized to process the outputs of the first layer. Finally, the result is determined by the Random Forest of the third layer. We compared the effectiveness of the combination of block composition, functional domain composition, and pseudoamino acid composition of the model. In the 11 kinds of functional protein families, QuaBingo is 23% of Matthews Correlation Coefficient (MCC) higher than the existing prediction system. The results also revealed the biological characterization of the top five block compositions. Conclusions. QuaBingo provides better predictive ability for predicting the quaternary structural attributes of proteins.

  7. Ancient dna from pleistocene fossils: Preservation, recovery, and utility of ancient genetic information for quaternary research

    NASA Astrophysics Data System (ADS)

    Yang, Hong

    Until recently, recovery and analysis of genetic information encoded in ancient DNA sequences from Pleistocene fossils were impossible. Recent advances in molecular biology offered technical tools to obtain ancient DNA sequences from well-preserved Quaternary fossils and opened the possibilities to directly study genetic changes in fossil species to address various biological and paleontological questions. Ancient DNA studies involving Pleistocene fossil material and ancient DNA degradation and preservation in Quaternary deposits are reviewed. The molecular technology applied to isolate, amplify, and sequence ancient DNA is also presented. Authentication of ancient DNA sequences and technical problems associated with modern and ancient DNA contamination are discussed. As illustrated in recent studies on ancient DNA from proboscideans, it is apparent that fossil DNA sequence data can shed light on many aspects of Quaternary research such as systematics and phylogeny. conservation biology, evolutionary theory, molecular taphonomy, and forensic sciences. Improvement of molecular techniques and a better understanding of DNA degradation during fossilization are likely to build on current strengths and to overcome existing problems, making fossil DNA data a unique source of information for Quaternary scientists.

  8. The insect response to climate change: Perspectives from the Quaternary record

    SciTech Connect

    Ashworth, A.C.; Schwert, D.P. . Quaternary Entomology Lab.)

    1993-03-01

    Data based on museum collections of insects are generally inadequate to answer questions related to the response of insects to recent and potential changes in climate. The most important source of information for this purpose is the late Quaternary fossil record. Abundant, well-preserved, [sup 14]C-dated assemblages of insect fossils provide information with which to answer the following questions: (1) will climate change result in speciation--all evidence suggests that species are constant through the climate changes of the late Quaternary, future climate change would not be expected to result in accelerated rates of speciation; (2) will climate change result in extinction--few species became extinct as a result of the large-scale changes in climate and physical environment during the quaternary, although large-scale extirpation might occur, future climate change would not be expected to result in widespread extinction of species; (3) will climate change result in changes in geographic distribution--species survived late Quaternary climatic change through the ability of individuals to disperse into suitable habitats. The result was large changes in geographic distribution of species, as exemplified by the succession of faunal changes that occurred in response to the climatic changes of the late Wisconsinan in the midcontinent, future climate change would be expected to result in significant range changes of species.

  9. 40 CFR 721.10666 - Quaternary ammonium compounds, bis(fattyalkyl) dimethyl, salts with tannins (generic).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...(fattyalkyl) dimethyl, salts with tannins (generic). 721.10666 Section 721.10666 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT SIGNIFICANT NEW USES OF CHEMICAL SUBSTANCES Significant New Uses for Specific Chemical Substances § 721.10666 Quaternary ammonium...

  10. Construction of Quaternary Stereocenters by Nickel-Catalyzed Heck Cyclization Reactions.

    PubMed

    Desrosiers, Jean-Nicolas; Hie, Liana; Biswas, Soumik; Zatolochnaya, Olga V; Rodriguez, Sonia; Lee, Heewon; Grinberg, Nelu; Haddad, Nizar; Yee, Nathan K; Garg, Neil K; Senanayake, Chris H

    2016-09-19

    A nickel-catalyzed Heck cyclization for the construction of quaternary stereocenters is reported. This transformation is demonstrated in the synthesis of 3,3-disubstituted oxindoles, which are prevalent motifs seen in numerous biologically active molecules. The method shows broad scope, proceeds in synthetically useful yields, and provides a rare means to construct stereochemically complex frameworks by nonprecious-metal catalysis. PMID:27600647

  11. QuaBingo: A Prediction System for Protein Quaternary Structure Attributes Using Block Composition

    PubMed Central

    Tung, Chi-Hua; Chen, Chi-Wei; Guo, Ren-Chao; Ng, Hui-Fuang

    2016-01-01

    Background. Quaternary structures of proteins are closely relevant to gene regulation, signal transduction, and many other biological functions of proteins. In the current study, a new method based on protein-conserved motif composition in block format for feature extraction is proposed, which is termed block composition. Results. The protein quaternary assembly states prediction system which combines blocks with functional domain composition, called QuaBingo, is constructed by three layers of classifiers that can categorize quaternary structural attributes of monomer, homooligomer, and heterooligomer. The building of the first layer classifier uses support vector machines (SVM) based on blocks and functional domains of proteins, and the second layer SVM was utilized to process the outputs of the first layer. Finally, the result is determined by the Random Forest of the third layer. We compared the effectiveness of the combination of block composition, functional domain composition, and pseudoamino acid composition of the model. In the 11 kinds of functional protein families, QuaBingo is 23% of Matthews Correlation Coefficient (MCC) higher than the existing prediction system. The results also revealed the biological characterization of the top five block compositions. Conclusions. QuaBingo provides better predictive ability for predicting the quaternary structural attributes of proteins. PMID:27610389

  12. Systematic paleontology of Quaternary ostracode assemblages from the Gulf of Alaska; Part 3, Family Cytheruridae

    USGS Publications Warehouse

    Brouwers, E.M.

    1994-01-01

    Forty-six species of podocopid ostracodes, most belonging to the Family Cytheruridae, are reported from Quaternary continental-shelf sediments of the Gulf of Alaska. Descriptions and illustrations are provided for 27 new species, 11 previously described species, and 8 species retained in open nomenclature. This report is based on 198 bottom grab samples collected during 1975, 1979, and 1980.

  13. Direct characterization of protein oligomers and their quaternary structures by single-molecule FRET.

    PubMed

    Kim, Cheolhee; Kim, Jae Yeol; Kim, Seung Hyeon; Lee, Byung Il; Lee, Nam Ki

    2012-01-28

    Using a single-molecule method, we directly distinguish among oligomers from monomers to tetramers and determine their quaternary structures. Using this method, we found that RecR forms a stable dimer and its oligomeric form is modulated by its own concentration and the interaction with RecO. PMID:22159510

  14. Synthesis of hierarchical zeolites using an inexpensive mono-quaternary ammonium surfactant as mesoporogen.

    PubMed

    Zhu, Xiaochun; Rohling, Roderigh; Filonenko, Georgy; Mezari, Brahim; Hofmann, Jan P; Asahina, Shunsuke; Hensen, Emiel J M

    2014-12-01

    A simple amphiphilic surfactant containing a mono-quaternary ammonium head group (N-methylpiperidine) is effective in imparting substantial mesoporosity during synthesis of SSZ-13 and ZSM-5 zeolites. Highly mesoporous SSZ-13 prepared in this manner shows greatly improved catalytic performance in the methanol-to-olefins reaction compared to bulk SSZ-13. PMID:25316609

  15. Antimicrobial Efficacy of Synthesized Quaternary Ammonium Polyamidoamine Dendrimers and Dendritic Polymer Network.

    PubMed

    Zainul Abid, C K V; Jackeray, Richa; Jain, Swati; Chattopadhyay, Sruti; Asif, S; Singh, Harpal

    2016-01-01

    Water treatment to mitigate microbial contaminants is a major challenge across globe paving the way to develop novel antimicrobial compounds. We aim at architecting antibacterial moiety eventually catering to vast water treatment industry. In this research study, quaternary ammonium functionalized polyamidoamine (PAMAM) dendrimer and PAMAM-ethyleneglycol dimethacrylate (EGDMA) dendritic polymer network were synthesized. These materials were characterized by various analytical techniques like ATR-FTIR, 1HNMR, DSC etc. Water soluble generation (G) 1.0 PAMAM dendrimer and water insoluble PAMAM G1.0 EGDMA dendritic polymer network were quaternized by reacting with dilute hydrochloric acid (HCI) and octyl iodide (01) respectively. Both quaternary ammonium dendrimer products were found to exhibit potent bactericidal activity against a group of common Gram-negative and Gram-positive bacteria. 10 mg/L concentration of liquid PAMAM G1.0 QHCI was efficient to kill 100% bacteria rapidly within an incubation time of just 2 minutes. In addition, quaternary ammonium dendritic polymer network PAMAM G1.0-EGDMA Q OI demonstrated good contact killing antimicrobial property without releasing any active molecule into the surrounding medium and disinfected contaminated water within 5 minutes. Both quaternary ammonium dendrimer and dendritic polymer network showed negligible cytotoxicity in MTT assay indicating their potential as a viable antimicrobial agent. PMID:27398560

  16. Stereodefined Acyclic Polysubstituted Silyl Ketene Aminals: Asymmetric Formation of Aldol Products with Quaternary Carbon Stereocenters.

    PubMed

    Nairoukh, Zackaria; Marek, Ilan

    2015-11-23

    The regio- and stereoselective formation of stereodefined polysubstituted silyl ketene aminals is easily achieved through selective combined carbometalation-oxidation-silylation reactions. These substrates are ideal candidates for Mukaiyama aldol reactions with aliphatic aldehydes as they give the aldol products with a quaternary carbon stereocenter α to the carbonyl groups in outstanding diastereoselectivities.

  17. Cyclopropene derivatives as precursors to enantioenriched cyclopropanols and n-butenals possessing quaternary carbon stereocenters.

    PubMed

    Simaan, Marwan; Delaye, Pierre-Olivier; Shi, Min; Marek, Ilan

    2015-10-12

    The diastereoselective carbocupration reaction of cyclopropenylmethyl ethers followed by addition of oxenoid leads to the formation of diastereo- and enantiomerically enriched 2,2,3,3-tetrasubstituted cyclopropanol derivatives. Ring fragmentation of the copper cyclopropanolate leads to acyclic butenal derivatives possessing enantiomerically enriched α-quaternary carbon stereocenters in a single-pot operation.

  18. Sulfated quaternary amine lipids: a new class of inverse charge zwitterlipids†

    PubMed Central

    Venditto, Vincent J.; Dolor, Aaron; Kohli, Aditya; Salentinig, Stefan; Boyd, Ben J.

    2014-01-01

    We describe a new class of charge inverted zwitterionic sulfated lipids (AS) with a cationic quaternary amine anchored at the membrane interface and an anionic sulfate moiety extended into the aqueous phase. These lipids have exceptionally high transition temperatures and assemble into lipid aggregates when dispersed in aqueous solutions. PMID:24984814

  19. QuaBingo: A Prediction System for Protein Quaternary Structure Attributes Using Block Composition

    PubMed Central

    Tung, Chi-Hua; Chen, Chi-Wei; Guo, Ren-Chao; Ng, Hui-Fuang

    2016-01-01

    Background. Quaternary structures of proteins are closely relevant to gene regulation, signal transduction, and many other biological functions of proteins. In the current study, a new method based on protein-conserved motif composition in block format for feature extraction is proposed, which is termed block composition. Results. The protein quaternary assembly states prediction system which combines blocks with functional domain composition, called QuaBingo, is constructed by three layers of classifiers that can categorize quaternary structural attributes of monomer, homooligomer, and heterooligomer. The building of the first layer classifier uses support vector machines (SVM) based on blocks and functional domains of proteins, and the second layer SVM was utilized to process the outputs of the first layer. Finally, the result is determined by the Random Forest of the third layer. We compared the effectiveness of the combination of block composition, functional domain composition, and pseudoamino acid composition of the model. In the 11 kinds of functional protein families, QuaBingo is 23% of Matthews Correlation Coefficient (MCC) higher than the existing prediction system. The results also revealed the biological characterization of the top five block compositions. Conclusions. QuaBingo provides better predictive ability for predicting the quaternary structural attributes of proteins.

  20. The influence of climate on species distribution over time and space during the late Quaternary

    NASA Astrophysics Data System (ADS)

    Carotenuto, F.; Di Febbraro, M.; Melchionna, M.; Castiglione, S.; Saggese, F.; Serio, C.; Mondanaro, A.; Passaro, F.; Loy, A.; Raia, P.

    2016-10-01

    Understanding the effect of climate on the composition of communities and its change over time and space is one of the major aims in ecology and paleoecology. Herein, we tackled on this issue by studying late Quaternary large mammal paleocommunities of Eurasia. The late Quaternary was a period of strong environmental instability, especially characterized by the occurrence of the last glacial maximum (LGM). We used community phylogenetics and joint species distribution models in order to understand the factors determining paleocommunity composition in the late Quaternary. Our results support the existence of strong climatic selection operating on the LGM fauna, both through the disappearance of warm-adapted species such as Elephas antiquus, Hippopothamus amphibious, and Stephanorhinus hemitoechus, and by setting the stage for the existence of a community characterized by cold-adapted large mammals. Patterns of abundance in the fossil record, co-occurrence between species pairs, and the extent of climatic forcing on faunal composition, differ between paleocommunities, but not between extinct and extant species, which is consistent with the idea that climate change, rather than the presence of humans, exerted a major effect on the survival of the late Quaternary megafauna.

  1. Dihydrothiophenes containing quaternary stereogenic centres by sequential stereospecific rearrangements and ring-closing metathesis.

    PubMed

    Mingat, Gaëlle; McDouall, Joseph J W; Clayden, Jonathan

    2014-06-28

    Stereospecific [3,3]-sigmatropic rearrangement of O-substituted thiocarbamate derivatives of enantiopure allylic alcohols provides allylic thiocarbamates as single enantiomers. Intramolecular arylation by rearrangement of their allyllithium derivatives provides allylic tertiary thiols. Allylation and ring-closing metathesis gives 2,5-dihydrothiophenes containing sulfur-bearing quaternary centres.

  2. Structural Analysis of Human and Macaque Monoclonal Antibodies 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120

    SciTech Connect

    B Spurrier; J Sampson; M Totrov; H Li; T ONeal; C Williams; J Robinson; M Gorny; S Zolla-Pazner; X Kong

    2011-12-31

    The quaternary neutralizing epitope (QNE) of HIV-1 gp120 is preferentially expressed on the trimeric envelope spikes of intact HIV virions, and QNE-specific monoclonal antibodies (mAbs) potently neutralize HIV-1. Here, we present the crystal structures of the Fabs of human mAb 2909 and macaque mAb 2.5B. Both mAbs have long beta hairpin CDR H3 regions >20 {angstrom} in length that are each situated at the center of their respective antigen-binding sites. Computational analysis showed that the paratopes include the whole CDR H3, while additional CDR residues form shallow binding pockets. Structural modeling suggests a way to understand the configuration of QNEs and the antigen-antibody interaction for QNE mAbs. Our data will be useful in designing immunogens that may elicit potent neutralizing QNE Abs.

  3. Structural Analysis of Human and Macaque Monoclonal Antibodies 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120

    PubMed Central

    Spurrier, Brett; Sampson, Jared M.; Totrov, Maxim; Li, Huiguang; O'Neal, Timothy; Williams, Constance; Robinson, James; Gorny, Miroslaw K.; Zolla-Pazner, Susan; Kong, Xiang-Peng

    2011-01-01

    Summary The quaternary neutralizing epitope (QNE) of HIV-1 gp120 is preferentially expressed on the trimeric envelope spikes of intact HIV virions, and QNE-specific monoclonal antibodies (mAbs) potently neutralize HIV-1. Here we present the crystal structures of the Fabs of human mAb 2909 and macaque mAb 2.5B. Both mAbs have long beta hairpin CDR H3 regions >20Å in length that are each situated at the center of their respective antigen-binding sites. Computational analysis showed that the paratopes include the whole CDR H3, while additional CDR residues form shallow binding pockets. Structural modeling suggests a way to understand the configuration of QNEs and the antigen antibody interaction for QNE mAbs. Our data will be useful in designing immunogens that may elicit potent neutralizing QNE Abs. PMID:21565703

  4. Dating of the late Quaternary volcanic events using Uranium-series technique on travertine deposit: A case study in Ihlara, Central Anatolia Volcanic Province

    NASA Astrophysics Data System (ADS)

    Karabacak, Volkan; Tonguç Uysal, İ.; Ünal-İmer, Ezgi

    2016-04-01

    Dating of late Quaternary volcanism is crucial to understanding of the recent mechanism of crustal deformation and future volcanic explosivity risk of the region. However, radiometric dating of volcanic products has been a major challenge because of high methodological error rate. In most cases, there are difficulties on discrimination of the volcanic lava flow relations in the field. Furthermore, there would be unrecorded and unpreserved volcanoclastic layers by depositional and erosional processes. We present a new method that allows precise dating of late Quaternary volcanic events (in the time range of 0-500,000 years before present) using the Uranium-series technique on travertine mass, which is thought to be controlled by the young volcanism. Since the high pressure CO2 in the spring waters are mobilized during crustal strain cycles and the carbonates are precipitated in the fissures act as conduit for hot springs, thus, travertine deposits provide important information about crustal deformation. In this study we studied Ihlara fissure ridge travertines in the Central Anatolia Volcanic Province. This region is surrounded by many eruption centers (i.e. Hasandaǧı, Acıgöl and Göllüdaǧı) known as the late Quaternary and their widespread volcanoclastic products. Recent studies have suggested at least 11 events at around Acıgöl Caldera for the last 180 ka and 2 events at Hasandaǧı Stratovolcano for the last 30 ka. Active travertine masses around Ihlara deposited from hotwaters, which rise up through deep-penetrated fissures in volcanoclastic products of surrounding volcanoes. Analyses of the joint systems indicate that these vein structures are controlled by the crustal deformation due to young volcanism in the vicinity. Thus, the geological history of Ihlara travertine mass is regarded as a record of surrounding young volcanism. We dated 9 samples from 5 ridge-type travertine masses around Ihlara region. The age distribution indicates that the crustal

  5. Late Quaternary seismic stratigraphy and structure of the western insular shelf margin of Puerto Rico

    NASA Astrophysics Data System (ADS)

    Hanzlik, M.; Mann, P.; Abrams, L.; Grindlay, N.

    2005-12-01

    725 km of high-resolution seismic data were collected over the insular shelf of western Puerto Rico to better understand its late Quaternary depositional and structural history. Due to low tectonic uplift rates of onshore areas in this region, well dated late Quaternary sediments and corals have only been identified in a few scattered onland localities around Puerto Rico. Seismic data from the Rio Anasco delta area of western Puerto Rico reveals four main units with characteristic stratal reflection terminations that total about 25 m in thickness. Because of a lack of well information, age estimates of these late Quaternary units are based on correlations with sea level curves derived from dated coral samples from Puerto Rico, St. Croix, and Antigua. Units include: Unit 1 - a gently folded and faulted basal section correlated to the Oliogene-early Pliocene? carbonate shelf of Puerto Rico; deeper penetration, industry MCS lines show that these rocks are deformed in a broad EW-trenching arch; Unit 2 - chaotic channel fill deposits in incisions related to the lowstand equivalent of the Rio Anasco likely formed during the Last Glacial Maximum about 25-15 ka; Unit 3 - roughly stratified deposits onlapping the top of Unit 2; these are interpreted as an estuarine facies deposited during Holocene sea level transgression; Unit 4 - highly stratified deposits related to progradation of the Anasco delta during sea level rise. The base of unit 4 is a downlap surface interpreted as a maximum flooding surface likely formed about 6 ka. East-northeast-striking faults are observed breaking the younger late Quaternary units in three separate zones off the west coast of Puerto Rico. Onland continuations of these faults have not been identified likely due to cultural overprint of natural scarps on late Quaternary floodplains.

  6. Late Quaternary faulting and historic seismicity in the western Lake Mead area, Nevada, Arizona and California

    SciTech Connect

    Anderson, L.W.; O'Connel, D.R. )

    1993-04-01

    As part of a regional seismic hazard study for Reclamation dams on the northern lower Colorado River, the age and distribution of known and suspected late Quaternary faults were investigated and historic seismicity was analyzed for the western Lake Mead area. Late Quaternary faults in the area consist of the Mead Slope, Black Hills, Frenchman Mountain, and California Wash faults. Geologic mapping and scarp profiles indicate that of these late Quaternary faults, the Black Hills fault displays evidence for the youngest (probably mid-Holocene) surface faulting. No information about the ages of older events was obtained for any of the faults; however, the ages of the most recent surface-rupturing events for individual faults suggest recurrence intervals of tens of thousands of years for specific faults and regional recurrence rates of several thousand years for M[sub 3] [>=] 6 1/2 events. Since 1936 when Hoover Dam was completed and the initial filling of Lake Mead began, the Boulder Basin area, the largest and deepest part of Lake Mead, has experienced abundant seismic activity that includes some of the largest historic earthquakes in southern Nevada (at least 21 M 4 events and one M 5). Based on earthquake locations from early networks (1937--1950) and those from temporary networks operating in 1975--1976 and 1988, earthquakes are clearly associated with the northeast-striking Mead Slope and Black Hills faults; one of the few associations of seismicity with late Quaternary faults in the Basin and Range. However, earthquakes also appear to be associated with the Fortification fault, a north-striking fault with no evidence of Quaternary surface faulting. Focal mechanisms for some of the 1975--1976 and 1988 events (all events M [<=] 3) suggest active strike-slip/oblique-slip motion on north-striking faults and normal/oblique-slip motion on northeast-striking structures.

  7. The Watergate Learning Center

    ERIC Educational Resources Information Center

    Training in Business and Industry, 1971

    1971-01-01

    The Watergate Learning Center, recently opened by Sterling Learning Center in Washington, D. C., blueprints the plan established by Sterling and Marriott Hotels for a national chain of learning centers with much the same facilities. (EB)

  8. Fireworks Information Center

    MedlinePlus

    ... Home / Safety Education / Safety Education Centers En Español Fireworks Information Center This is an information center on ... Video Put Safety First This Fourth of July Fireworks Information What are consumer fireworks and where are ...

  9. Children's cancer centers

    MedlinePlus

    Pediatric cancer center; Pediatric oncology center; Comprehensive cancer center ... Treating childhood cancer is not the same as treating adult cancer. The cancers are different. So are the treatments and the ...

  10. Spatiotemporal analysis of Quaternary normal faults in the Northern Rocky Mountains, USA

    NASA Astrophysics Data System (ADS)

    Davarpanah, A.; Babaie, H. A.; Reed, P.

    2010-12-01

    The mid-Tertiary Basin-and-Range extensional tectonic event developed most of the normal faults that bound the ranges in the northern Rocky Mountains within Montana, Wyoming, and Idaho. The interaction of the thermally induced stress field of the Yellowstone hot spot with the existing Basin-and-Range fault blocks, during the last 15 my, has produced a new, spatially and temporally variable system of normal faults in these areas. The orientation and spatial distribution of the trace of these hot-spot induced normal faults, relative to earlier Basin-and-Range faults, have significant implications for the effect of the temporally varying and spatially propagating thermal dome on the growth of new hot spot related normal faults and reactivation of existing Basin-and-Range faults. Digitally enhanced LANDSAT 7 Enhanced Thematic Mapper Plus (ETM+) and Landsat 4 and 5 Thematic Mapper (TM) bands, with spatial resolution of 30 m, combined with analytical GIS and geological techniques helped in determining and analyzing the lineaments and traces of the Quaternary, thermally-induced normal faults in the study area. Applying the color composite (CC) image enhancement technique, the combination of bands 3, 2 and 1 of the ETM+ and TM images was chosen as the best statistical choice to create a color composite for lineament identification. The spatiotemporal analysis of the Quaternary normal faults produces significant information on the structural style, timing, spatial variation, spatial density, and frequency of the faults. The seismic Quaternary normal faults, in the whole study area, are divided, based on their age, into four specific sets, which from oldest to youngest include: Quaternary (>1.6 Ma), middle and late Quaternary (>750 ka), latest Quaternary (>15 ka), and the last 150 years. A density map for the Quaternary faults reveals that most active faults are near the current Yellowstone National Park area (YNP), where most seismically active faults, in the past 1.6 my

  11. Quaternary structure of carbonmonoxyhemoglobins in solution: structural changes induced by the allosteric effector inositol hexaphosphate.

    PubMed

    Gong, Qingguo; Simplaceanu, Virgil; Lukin, Jonathan A; Giovannelli, Janel L; Ho, Nancy T; Ho, Chien

    2006-04-25

    We have applied the residual dipolar coupling (RDC) method to investigate the solution quaternary structures of (2)H- and (15)N-labeled human normal adult recombinant hemoglobin (rHb A) and a low-oxygen-affinity mutant recombinant hemoglobin, rHb(alpha96Val-->Trp), both in the carbonmonoxy form, in the absence and presence of an allosteric effector, inositol hexaphosphate (IHP), using a stretched polyacrylamide gel as the alignment medium. Our recent RDC results [Lukin, J. A., Kontaxis, G., Simplaceanu, V., Yuan, Y., Bax, A., and Ho, C. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 517-520] indicate that the quaternary structure of HbCO A in solution is a dynamic ensemble between two previously determined crystal structures, R (crystals grown under high-salt conditions) and R2 (crystals grown under low-salt conditions). On the basis of a comparison of the geometric coordinates of the T, R, and R2 structures, it has been suggested that the oxygenation of Hb A follows the transition pathway from T to R and then to R2, with R being the intermediate structure [Srinivasan, R., and Rose, G. D. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 11113-11117]. The results presented here suggest that IHP can shift the solution quaternary structure of HbCO A slightly toward the R structure. The solution quaternary structure of rHbCO(alpha96Val-->Trp) in the absence of IHP is similar to that of HbCO A in the presence of IHP, consistent with rHbCO(alpha96Val-->Trp) having an affinity for oxygen lower than that of Hb A. Moreover, IHP has a much stronger effect in shifting the solution quaternary structure of rHbCO(alpha96Val-->Trp) toward the R structure and toward the T structure, consistent with IHP causing a more pronounced decrease in its oxygen affinity. The results presented in this work, as well as other results recently reported in the literature, clearly indicate that there are multiple quaternary structures for the ligated form of hemoglobin. These results also provide new insights

  12. Dryden Flight Research Center: Center Overview

    NASA Technical Reports Server (NTRS)

    Ratnayake, Nalin

    2009-01-01

    This viewgraph presentation describes a general overview of Dryden Flight Research Center. Strategic partnerships, Dryden's mission activity, exploration systems and aeronautics research programs are also described.

  13. Women's Centers: The Frameworks.

    ERIC Educational Resources Information Center

    Wetzel, Jodi

    1988-01-01

    Presents a typology of women's centers and provides an overview of state, regional, and national networks of women's centers, including the evolution of the Women's Center/Services Caucus of the National Women's Studies Association and the more recently organized National Association of Women's Centers. (NB)

  14. Student Success Center Toolkit

    ERIC Educational Resources Information Center

    Jobs For the Future, 2014

    2014-01-01

    "Student Success Center Toolkit" is a compilation of materials organized to assist Student Success Center directors as they staff, launch, operate, and sustain Centers. The toolkit features materials created and used by existing Centers, such as staffing and budgeting templates, launch materials, sample meeting agendas, and fundraising…

  15. From Teacher Centered to Student Centered Learning.

    ERIC Educational Resources Information Center

    Lockemy, M. J.; Summers, Sylvia

    In 1991, staff at the Business Resource Center (BRC) at Tacoma Community College, in Washington, began to reevaluate their approach to serving students. Up to that point, the BRC had been teacher centered, with staff operating under the assumptions that only the students who succeeded were actually "college material," that students would cheat if…

  16. Optical analysis of lens-like Cu2CdSnS4 quaternary alloy nanostructures

    NASA Astrophysics Data System (ADS)

    Odeh, Ali Abu; Al-Douri, Y.; Ayub, R. M.; Ameri, M.; Bouhemadou, A.; Prakash, Deo; Verma, K. D.

    2016-10-01

    Cu2CdSnS4 quaternary alloy nanostructures with different copper concentrations (0.2, 0.4, 0.6, 0.8 and 1.0 M) were successfully synthesized on n-type silicon substrates using spin coating technique with annealing temperature at 300 °C. Optical properties were analyzed through UV-Vis and Photoluminescence spectroscopies, and thus, there is a change in energy band gap with increasing Cu concentration from 0.2 to 1.0 M. The structural properties of Cu2CdSnS4 quaternary alloy nanostructures were investigated by X-ray diffraction. The particles size and shape have a direct relationship with copper concentration. Morphological and topographical studies were carried out by using scanning electron microscopy and atomic force microscopy. The obtained results are investigated to be available in the literature for future studies.

  17. Antimicrobial cotton containing N-halamine and quaternary ammonium groups by grafting copolymerization

    NASA Astrophysics Data System (ADS)

    Liu, Ying; Liu, Yin; Ren, Xuehong; Huang, T. S.

    2014-03-01

    The monomer (3-acrylamidopropyl)trimethylammonium chloride (APTMAC) was used to treat cotton fibers by grafting copolymerization. The grafted cotton fabrics were characterized by SEM image and FTIR spectra. The treated samples with quaternary ammonium groups could decrease 96.08% of Staphylococcus aureus and 48.74% of Escherichia coli O157:H7 within 30 min. After chlorination with dilute sodium hypochlorite, the treated cotton fabrics containing both N-halamine and quaternary ammonium groups effectively inactivated 100% (log reduction 5.82) of S. aureus and 100% (log reduction 6.26) of E. coli O157:H7 within 5 min of contact time. The grafting process of cotton fabric has small effect on the thermal stability and tensile strength, which favors the practical application. Compared to the traditional pad-dry-cure method to produce antibacterial materials, the radical grafting copolymerization method occurred in water without any organic solvents involved in the whole treatment.

  18. North American Pika ( Ochotona princeps) as a Late Quaternary Biogeographic Indicator Species

    NASA Astrophysics Data System (ADS)

    Hafner, David J.

    1993-05-01

    Reevaluation of Quaternary sites of fossil pika ( Ochotona) lends no support for the inference that Nearctic pikas were not restricted to rocky habitat. The saxicolous nature of all widespread, isolated populations of extant Nearctic pikas and their closest Palearctic sister taxa support consideration of O. princeps, and perhaps all Nearctic Quaternary Ochotona , as indicators of cool, mesic, rocky situations. As indicators of rocky microhabitat, fossil remains of O. princeps do not require that the entire region was cool and mesic, but only that suitable rocky microhabitat existed in the vicinity. Use of fossil pika dung alone as indicative of pikas in the immediate community is suspect, as the small, round, and buoyant pellets may be transported downslope by hydraulic flushing of talus habitat. Current local elevational lower limits ( E) of appropriate habitat for paleoecological reconstruction at extralimital fossil sites are predicted by the equation: E(m) = 14087 - (56.6)°N - (82.9)°W.

  19. Quaternary geologic map of the Boston 4 degrees x 6 degrees quadrangle, United States and Canada

    USGS Publications Warehouse

    State compilations by Hartshorn, Joseph H.; Thompson, W.B.; Chapman, W.F.; Black, R.F.; Richmond, Gerald Martin; Grant, D.R.; Fullerton, David S.; edited and integrated by Richmond, Gerald Martin

    1991-01-01

    The Quaternary Geologic Map of the Boston 4 deg x 6 deg Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the earth. They make up the 'ground' on which we walk, the 'dirt' in which we dig foundations, and the 'soil' in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale.

  20. Microtitration of various anions with quaternary ammonium halides using solid-state electrodes

    SciTech Connect

    Selig, W.

    1980-01-01

    Many solid-state electrodes were found to respond as endpoint detectors in the potentiometric titration of large inorganic and organic anions with quaternary ammonium halides. The best response was obtained with the iodide and cyanide electrodes although practically any electrode can function as endpoint sensor. The titrants were hexadecylpyridinium chloride and hexadecyltrimethylammonium chloride; hexadecyltrimethylammonium bromide and Hyamine 1622 may also be used. Some inorganic anions thus titratable are perrhenate, persulfate, ferricyanide, hexafluorophosphate, and hexachloroplatinate. Examples of organic anions titratable are nitroform, tetraphenylborate, cyanotriphenylborate, picrate, long-chain sulfates and sulfonates, and some soaps. The reverse titration of quaternary ammonium halides vs dodecylsulfate is also feasible. Some titrations are feasible in a partially nonaqueous medium.

  1. Biotic response to late Quaternary rapid climate switches in Santa Barbara Basin: Ecological and evolutionary implications

    SciTech Connect

    Cannariato, K.G.; Kennett, J.P.; Behl, R.J.

    1999-01-01

    Benthic foraminiferal assemblages from Santa Barbara Basin exhibit major faunal and ecological switches associated with late Quaternary millennial- to decadal-scale global climate oscillations. Repeated turnovers of entire faunas occurred rapidly (<40--400 yr) without extinction or speciation in conjunction with Dansgaard-Oeschger shifts in thermohaline circulation, ventilation, and climate, confirming evolutionary model predictions of Roy et al. Consistent faunal successions of dysoxic taxa during successive interstadials reflect the extreme sensitivity and adaptation of the benthic ecosystem to the rapid environmental changes that marked the late Quaternary and possibly other transitional intervals in the history of the Earth`s ocean-atmosphere-cryosphere system. These data support the hypothesis that broad segments of the biosphere are well adapted to rapid climate change.

  2. How have studies of ancient DNA from sediments contributed to the reconstruction of Quaternary floras?

    PubMed

    Birks, H John B; Birks, Hilary H

    2016-01-01

    499 I. 499 II. 500 III. 500 IV. 500 V. 500 VI. 501 VII. 502 VIII. 504 504 References 505 SUMMARY: Ancient DNA (aDNA) from lake sediments, peats, permafrost soils, preserved megafaunal gut contents and coprolites has been used to reconstruct late-Quaternary floras. aDNA is either used alone for floristic reconstruction or compared with pollen and/or macrofossil results. In comparative studies, aDNA may complement pollen and macrofossil analyses by increasing the number of taxa found. We discuss the relative contributions of each fossil group to taxon richness and the number of unique taxa found, and situations in which aDNA has refined pollen identifications. Pressing problems in aDNA studies are contamination and ignorance about taphonomy (transportation, incorporation, and preservation in sediments). Progress requires that these problems are reduced to allow aDNA to reach its full potential contribution to reconstructions of Quaternary floras. PMID:26402315

  3. Fossil oribatid mites (Acari, Oribatida) from the Florisbad Quaternary deposits, South Africa

    NASA Astrophysics Data System (ADS)

    Coetzee, Louise; Brink, James S.

    2003-03-01

    In a pioneer application of acarology to Quaternary fossil-bearing sediments in southern Africa, the oribatid composition in the Florisbad Quaternary sediments was determined and compared to the currently known distribution of those species. Nine species of oribatid mites were recorded in the Holocene aeolian deposits of the third test pit, three species from the Middle Stone Age (MSA) horizon sediments of the third test pit, and thirteen species from the Holocene spring sediments. The Florisbad results indicate a better agreement between the oribatid fauna of the last interglacial MSA horizon of the third test pit and the organic-rich mid-Holocene deposits near the spring than between either of these and early- and late-Holocene aeolian sediments of the third test pit, suggesting some similarity in microsedimentary environments. The majority of the species recorded in the sediments are parthenogenetic and can be regarded as pioneer species.

  4. Subsurface geology of upper Tertiary and Quaternary deposits, coastal Louisiana and adjacent Continental Shelf

    SciTech Connect

    McFarlan, E. Jr.; Leroy, D.O.

    1988-09-01

    Upper Tertiary and Quaternary deposits thicken seaward from a feather edge on the outcrop in the uplands of southern Louisiana to more than 7000 ft (2134 m) beneath the middle continental shelf. Through a study of cores and cuttings from 100 control wells and electric-log pattern correlations from 350 water and petroleum industry wells with seismic corroboration in the offshore area, these deposits have been divided into six major time-stratigraphic units, four of which correlate to outcropping terraces. This investigation presents a regional stratigraphic framework of the major upper Tertiary and Quaternary units from their updip pinch-outs in and beneath the terraced uplands, into the subsurface, across the coastal plain to the Louisiana offshore area.

  5. Quaternary geologic map of the Sudbury 4 degree by 6 degree quadrangle, United States and Canada

    USGS Publications Warehouse

    Fullerton, David S.; Sado, Edward V.; Baker, C.L.; Farrand, William R.

    2004-01-01

    The Quaternary Geologic Map of the Sudbury 4 degrees x 6 degrees Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the earth. They make up the 'ground' on which we walk, the 'dirt' in which we dig foundations, and the 'soil' in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale.

  6. Quaternary geologic map of the Chicago 4 degrees x 6 degrees quadrangle, United States

    USGS Publications Warehouse

    State compilations by Lineback, Jerry A.; Bleuer, Ned K.; Mickelson, David M.; Farrand, William R.; Goldthwait, Richard P.; Edited and integrated by Richmond, Gerald M.; Fullerton, David S.

    1983-01-01

    The Quaternary Geologic Map of the Chicago 4 degree x 6 degree Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the earth. They make up the 'ground' on which we walk, the 'dirt' in which we dig foundations, and the 'soil' in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale.

  7. Quaternary geologic map of the Ottawa 4 degrees x 6 degrees quadrangle, United States and Canada

    USGS Publications Warehouse

    Fullerton, David S.; Gadd, N. R.; Veillette, J.J.; Wagner, P.W.; Chapman, W.F.

    1993-01-01

    The Quaternary Geologic Map of the Ottawa 4 degree x 6 degree Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the earth. They make up the 'ground' on which we walk, the 'dirt' in which we dig foundations, and the 'soil' in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale.

  8. Enantioselective construction of quaternary N-heterocycles by palladium-catalysed decarboxylative allylic alkylation of lactams

    NASA Astrophysics Data System (ADS)

    Behenna, Douglas C.; Liu, Yiyang; Yurino, Taiga; Kim, Jimin; White, David E.; Virgil, Scott C.; Stoltz, Brian M.

    2012-02-01

    The enantioselective synthesis of nitrogen-containing heterocycles (N-heterocycles) represents a substantial chemical research effort and resonates across numerous disciplines, including the total synthesis of natural products and medicinal chemistry. In this Article, we describe the highly enantioselective palladium-catalysed decarboxylative allylic alkylation of readily available lactams to form 3,3-disubstituted pyrrolidinones, piperidinones, caprolactams and structurally related lactams. Given the prevalence of quaternary N-heterocycles in biologically active alkaloids and pharmaceutical agents, we envisage that our method will provide a synthetic entry into the de novo asymmetric synthesis of such structures. As an entry for these investigations we demonstrate how the described catalysis affords enantiopure quaternary lactams that intercept synthetic intermediates previously used in the synthesis of the Aspidosperma alkaloids quebrachamine and rhazinilam, but that were previously only available by chiral auxiliary approaches or as racemic mixtures.

  9. The quaternary structure of the ribosome from E. coli. A neutron small-angle scattering study

    NASA Astrophysics Data System (ADS)

    Nowotny, V.; Nowotny, P.; Voß, H.; Nierhaus, K. H.; May, R. P.

    1989-01-01

    Ribosomes synthesize proteins in living cells. The E. coli ribosome is composed of a small (30S) and a large subunit (50S). They consist of different proteins (21 or 34, respectively) and of ribosomal RNAs (16S or 23S and 5S). The inter-protein distances within the ribosomal subunits can be measured from scattering experiments with selectively labeled protein pairs from which the quaternary distribution of the proteins is reconstructed. We have developed the strategy of the “glassy ribosome”: the rRNAs and the proteins are deuterated such that they reach the same scattering density and are “invisible” in a corresponding buffer solution. A preliminary quaternary map of the 50S subunit which is the result of our new method for the extraction of the distances from the scattering data as well as shape parameters of proteins in situ will be presented.

  10. New insights into the earliest Quaternary environments in the Central North Sea from 3D seismic

    NASA Astrophysics Data System (ADS)

    Lamb, Rachel; Huuse, Mads; Stewart, Margaret; Brocklehurst, Simon H.

    2014-05-01

    In the past the transition between an unconformable surface in the south to a conformable horizon towards the north has made identification and mapping the base-Quaternary in the central North Sea difficult (Sejrup et al 1991; Gatliff et al 1994). However recent integration of biostratigraphy, pollen analysis, paleomagnetism and amino acid analysis in the Dutch and Danish sectors (Rasmussen et al 2005; Kuhlmann et al 2006) has allowed greater confidence in the correlation to the region 3D seismic datasets and thus has allowed the base-Quaternary to be mapped across the entire basin. The base-Quaternary has been mapped using the PGS MegaSurvey dataset from wells in the Danish Sector along the initially unconformable horizon and down the delta front into the more conformable basin giving a high degree of confidence in the horizon pick. The revised base-Quaternary surface reaches a depth of 1248 ms TWT with an elongate basin shape which is significantly deeper than the traditionally mapped surface. Using RMS amplitudes and other seismic attributes the revised base-Quaternary has been investigated along the horizon and in time slice to interpret the environments of the earliest Quaternary prior to the onset of glaciation. Combined with analysis of aligned elongate furrows over 10 km long, 100 m wide and 100 m deep suggest a deep marine environment in an almost enclosed basin with persistent strong NW-SE bottom currents in the deepest parts. Pockmarks were formed by the escape of shallow gas on the sides of a small delta in the eastern part of the basin. The progradation of large deltas from both the north and south into the basin make up the majority of the deposition of sediment into the basin. Key Words: base-Quaternary; seismic interpretation; paleoenvironments References: Gatliff, R.W, Richards, P.C, Smith, K, Graham, C.C, McCormac, M, Smith, N.J.P, Long, D, Cameron, T.D.J, Evans, D, Stevenson, A.G, Bulat, J, Ritchie, J.D, (1994) 'United Kingdom offshore regional

  11. Hydrolysed ginseng-saponin quaternary: a novel conditioning agent for hair care products.

    PubMed

    Young-Dae, K; Chang-Kew, K; Chung-Nam, L; Byung-Jo, H

    1989-10-01

    Synopsis A new quaternary ammonium compound, hydrolysed ginseng-saponin quaternary (HGSQ), from Korean ginseng saponin and 2,3-epoxypropyltrimethyl ammonium chloride, has been developed as a conditioning agent for hair care products. This structure has a hydrophobic group from the aglycone of ginseng saponin which is biologically active and considered as the most important component of Korean ginseng. Its properties of surface tension, conductivity, critical micelle concentration (CMC), eye irritation, sorption onto hair, tensile strength for 20% extension and moisture retention effect were studied. Its cationic character allows the molecule to be more substantive than ginseng saponin. HGSQ had good physical properties and was safe enough as a cosmetic raw material. Also half-head tests of HGSQ-containing shampoo were carried out to evaluate the conditioning effects in shampoos. HGSQ showed good conditioning properties in a shampoo.

  12. Quaternary geologic map of the Chesapeake Bay 4 degrees x 6 degrees quadrangle, United States

    USGS Publications Warehouse

    State compilations by Cleaves, Emery T.; Glaser, John D.; Howard, Alan D.; Johnson, Gerald H.; Wheeler, Walter H.; Sevon, William D.; Judson, Sheldon; Owens, James P.; Peebles, Pamela C.; edited and integrated by Richmond, Gerald Martin; Fullerton, David S.; Weide, David L.

    1987-01-01

    The Quaternary Geologic Map of the Chesapeake Bay 4? x 6? Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the Earth. They make up the 'ground' on which we walk, the 'dirt' in which we dig foundations, and the 'soil' in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale.

  13. Synthesis, antioxidant and cathepsin D inhibition activity of quaternary ammonium chitosan derivatives.

    PubMed

    Li, Wenjuan; Duan, Yunfei; Huang, Jianying; Zheng, Qunxiong

    2016-01-20

    Two (2-hydroxypropyl) trimethyl ammonium and/or imidazole-based quaternary ammonium chitosan derivatives (NHT-chitosan and Im-OHT-chitosan) were synthesized by using nucleophilic substitution reaction. These two synthesized chitosan derivatives were characterized by Fourier transform infrared spectroscopy, NMR spectra, and UV-visible spectra. The applications as antioxidant agents and cathepsin D inhibitors were further investigated. Both of quaternary ammonium chitosan derivatives exhibited good antioxidant activity upon scavenging against hydroxyl radical and hydrogen peroxide as well as the lipid peroxidation inhibition in the linoleic acid emulsion system. They also exhibited good inhibition activity of cathepsin D protease. NHT-chitosan and Im-OHT-chitosan are potential the natural, healthy and safe preservatives in food industry.

  14. Preliminary observations on Quaternary reverse faulting along the southern front of the Northern Range of Trinidad

    SciTech Connect

    Beltran, C. , Caracus )

    1993-02-01

    Several geomorphological evidences of Quaternary reverse faulting are observed along the southern front of the Northern Range in Trinidad between Port-of-Spain and Matura Point. Such a mountain front is associated to a reverse fault system showing an imbricated pattern southward. In the north, the system is limited by a structural feature showing an important vertical component. Southward this system progressively changes to low angle faults. This geometry is corroborated by seismic profiling in the continent shelf. The active faulting evidences consist in lateral drainage offsets, fault trenches, sag-ponds, triangular facets, and saddles. Some quaternary terraces show fault scarps and tilting. We postulate that these reverse fault systems as Arima Fault instead of El Pilar fault as it is not actually connected to the San Sebestian-El Pilar right-lateral slip system, due to the southward prolongation of the southern limit of the Caribbean Plate through the fault system of Los Bajos-El Soldado.

  15. Quaternary geologic map of the Dallas 4° x 6° quadrangle, United States

    USGS Publications Warehouse

    State compilations by Luza, Kenneth V.; Jensen, Kathleen M.; Fishman, W.D.; Wermund, E.G.; Richmond, Gerald Martin; edited and integrated by Richmond, Gerald Martin; Christiansen, Ann Coe; Digital edition by Bush, Charles A.

    1994-01-01

    The Quaternary Geologic Map of the Dallas 4° x 6° Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the Earth. They make up the ground on which we walk, the dirt in which we dig foundations, and the soil in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale.

  16. Quaternary geologic map of the Ozark Plateau 4 ° x 6 ° quadrangle, United States

    USGS Publications Warehouse

    State compilations by Whitfield, John William; Ward, R.A.; Denne, J.E.; Holbrook, D.F.; Bush, W.V.; Lineback, J.A.; Luza, K.V.; Jensen, Kathleen M.; Fishman, W.D.; Richmond, Gerald Martin; Weide, David L.; Digital edition by Bush, Charles A.

    1993-01-01

    The Quaternary Geologic Map of the Ozark Plateau 4° x 6° Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the earth. They make up the "ground" on which we walk, the "dirt" in which we dig foundations, and the "soil" in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale.

  17. Ion Mobility-Mass Spectrometry Differentiates Protein Quaternary Structures Formed in Solution and in Electrospray Droplets.

    PubMed

    Han, Linjie; Ruotolo, Brandon T

    2015-07-01

    Electrospray ionization coupled to mass spectrometry is a key technology for determining the stoichiometries of multiprotein complexes. Despite highly accurate results for many assemblies, challenging samples can generate signals for artifact protein-protein binding born of the crowding forces present within drying electrospray droplets. Here, for the first time, we study the formation of preferred protein quaternary structures within such rapidly evaporating nanodroplets. We use ion mobility and tandem mass spectrometry to investigate glutamate dehydrogenase dodecamers and serum amyloid P decamers as a function of protein concentration, along with control experiments using carefully chosen protein analogues, to both establish the formation of operative mechanisms and assign the bimodal conformer populations observed. Further, we identify an unprecedented symmetric collision-induced dissociation pathway that we link directly to the quaternary structures of the precursor ions selected.

  18. Methane in ground ice and frozen Quaternary deposits of Western Yamal

    NASA Astrophysics Data System (ADS)

    Vasiliev, A. A.; Streletskaya, I. D.; Melnikov, V. P.; Oblogov, G. E.

    2015-12-01

    The content and the genesis of methane in underground ice and frozen Quaternary sediments of Western Yamal is studied. The minimum concentration of methane in frozen Quaternary deposits was found for sand: 15-100 ppm V. The maximum concentration of methane reaches 3000 ppm V in marine clays. The concentration of methane in the ice wedges is 100-700 ppm V, and in the massive ground ice can be more than 10 000 ppm V. The high content of methane in the massive ground ice we explain by migration of methane from freezing deposits into ice body during its formation. The close connection between methane concentration and organic carbon content is found.

  19. β-CD assisted dissolution of quaternary ammonium permanganates in aqueous medium.

    PubMed

    Bank, Suraj Prakash; Guru, Partha Sarathi; Dash, Sukalyan

    2014-10-13

    The non-polar internal cavity of β-cyclodextrin (β-CD) has been exploited for the entrapment of the hydrophobic tails of two water insoluble quaternary ammonium permanganates (QAPs): cetyltrimethylammonium permanganate (CTAP) and tetrabutylammonium permanganate (TBAP), for solubilization in aqueous medium. The solubilization and organizational behavior of the QAPs in aqueous β-CD solution have been determined from the comparison of their rates of self-oxidation in presence and in absence of β-CD. Effect of QAP concentration on their observed rate constants (k(obs)) at a fixed β-CD concentration, phase solubility analysis in varying β-CD concentration, impact of quaternary ammonium bromides (QABs) on the kobs values of CTAP and TBAP at fixed QAP and β-CD concentrations, and the temperature effect have been reported. A scheme to explain the solvation of QAPs in aqueous β-CD has been proposed based on dynamic light scattering (DLS) analysis of the samples.

  20. Quaternary geologic map of the Quebec 4 degrees x 6 degrees quadrangle, United States and Canada

    USGS Publications Warehouse

    State compilations by Borns, H. W.; Gadd, N.R.; LaSalle, Pierre; Martineau, Ghismond; Chauvin, Luc; Fulton, R.J.; Chapman, W.F.; Wagner, W.P.; Grant, D.R.; edited and integrated by Richmond, Gerald Martin; Fullerton, David S.

    1987-01-01

    The Quaternary Geologic Map of the Quebec 4? x 6? Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the Earth. They make up the 'ground' on which we walk, the 'dirt' in which we dig foundations, and the 'soil' in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale.

  1. Heme Reactivity is Uncoupled from Quaternary Structure in Gel-encapsulated Hemoglobin: A Resonance Raman Spectroscopic Study

    PubMed Central

    Jones, Eric M.; Balakrishnan, Gurusamy; Spiro, Thomas G.

    2012-01-01

    Encapsulation of hemoglobin (Hb) in silica gel preserves structure and function, but greatly slows protein motion, thereby providing access to intermediates along the allosteric pathway that are inaccessible in solution. Resonance Raman (RR) spectroscopy with visible and ultraviolet laser excitation provides probes of heme reactivity and of key tertiary and quaternary contacts. These probes were monitored in gels after deoxygenation of oxyHb and after CO binding to deoxyHb, which intiate conformational change in the R-T and T-R directions, respectively. The spectra establish that quaternary structure change in the gel takes a week or more, but that the evolution of heme reactivity, as monitored by the Fe-histidine stretching vibration, νFeHis, is completed within two days, and is therefore uncoupled from the quaternary structure. Within each quaternary structure, the evolving νFeHis frequencies span the full range of values between those previously associated with the high- and low-affinity end states, R and T. This result supports the tertiary two-state (TTS) model, in which the Hb subunits can adopt high- and low-affinity tertiary structures, r and t, within each quaternary state. The spectra also reveal different tertiary pathways, involving the breaking and re-formation of E and F inter-helical contacts in the R-T direction but not the T-R direction. In the latter, tertiary motions are restricted by the T quaternary contacts. PMID:22263778

  2. Application of rock varnish dating of quaternary surficial deposits in determining times of fault movement

    SciTech Connect

    Harrington, C.D.

    1987-01-01

    Rock varnish, a coating commonly found on rock surfaces in arid and semiarid regions, has a significant potential in paleoseismic studies, as a wide variety of Quaternary surfaces and surficial deposits can be dated with the rock varnish technique. If the formation of geomorphic surfaces or surficial deposits can be related to times of faulting or if faulting has broken or deformed such features, then rock varnish dating can be used to constrain maximum and minimum times of motion on the related fault.

  3. Enantioselective Synthesis of α-Quaternary Amino Acids by Alkylation of Deprotonated α-Aminonitriles.

    PubMed

    Netz, Isabelle; Kucukdisli, Murat; Opatz, Till

    2015-07-01

    A series of α-quaternary arylglycines were prepared in high optical purity (up to 98% ee) by α-alkylation of deprotonated α-aminonitriles derived by the Strecker reaction from (4S,5S)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane. The procedure includes only chromatographic purification of the final products and is devoid of chromatography or crystallization operations on intermediates to raise the optical purity. PMID:26024300

  4. Quaternary grabens in southernmost Illinois: Deformation near an active intraplate seismic zone

    USGS Publications Warehouse

    Nelson, W.J.; Denny, F.B.; Follmer, L.R.; Masters, J.M.

    1999-01-01

    Narrow grabens displace Quaternary sediments near the northern edge of the Mississippi Embayment in extreme southern Illinois, east-central United States. Grabens are part of the Fluorspar Area Fault Complex (FAFC), which has been recurrently active throughout Phanerozoic time. The FAFC strikes directly toward the New Madrid Seismic Zone (NMSZ), scene of some of the largest intra-plate earthquakes in history. The NMSZ and FAFC share origin in a failed Cambrian rift (Reelfoot Rift). Every major fault zone of the FAFC in Illinois exhibits Quaternary displacement. The structures appear to be strike-slip pull-apart grabens, but the magnitude and direction of horizontal slip and their relationship to the current stress field are unknown. Upper Tertiary strata are vertically displaced more than 100 m, Illinoian and older Pleistocene strata 10 to 30 m, and Wisconsinan deposits 1 m or less. No Holocene deformation has been observed. Average vertical slip rates are estimated at 0.01 to 0.03 mm/year, and recurrence intervals for earthquakes of magnitude 6 to 7 are on the order of 10,000s of years for any given fault. Previous authors remarked that the small amount of surface deformation in the New Madrid area implies that the NMSZ is a young feature. Our findings show that tectonic activity has shifted around throughout the Quaternary in the central Mississippi Valley. In addition to the NMSZ and southern Illinois, the Wabash Valley (Illinois-Indiana), Benton Hills (Missouri), Crowley's Ridge (Arkansas-Missouri), and possibly other sites have experienced Quaternary tectonism. The NMSZ may be only the latest manifestation of seismicity in an intensely fractured intra-plate region.

  5. Enantioselective iodolactonization catalyzed by chiral quaternary ammonium salts derived from cinchonidine.

    PubMed

    Wang, Mang; Gao, Lian Xun; Mai, Wen Peng; Xia, Ai Xiang; Wang, Fang; Zhang, Suo Bo

    2004-04-16

    Chiral quaternary ammonium salts derived from cinchonidine have been applied to catalyze the stereoselective iodolactonizations of trans-5-aryl-4-pentenoic acids leading to a mixture of two regioselectively iodolactonized products with fair to excellent yield (37-98%) and moderate enantioselectivity (exo = 42.0% ee, endo = 31.0% ee) under mild conditions. This work is the first example of asymmetric iodolactonization reaction in the presence of less than a stoichiometric amount of chiral reagent.

  6. Late Quaternary glaciation of the Upper Soca River Region (Southern Julian Alps, NW Slovenia)

    USGS Publications Warehouse

    Bavec, Milos; Tulaczyk, Slawek M.; Mahan, Shannon; Stock, Gregory M.

    2004-01-01

    Extent of Late Quaternary glaciers in the Upper Soc??a River Region (Southern Julian Alps, SE Europe) has been analyzed using a combination of geological mapping, glaciological modeling, and sediment dating (radiocarbon, U/Th series and Infrared Stimulated Luminescence-IRSL). Field investigations focused mainly on relatively well preserved Quaternary sequences in the Bovec Basin, an intramontane basin located SW of the Mediterranean/Black Sea divide and surrounded by mountain peaks reaching from approximately 2100 up to 2587 m a.s.l. Within the Basin we recognized two Late Quaternary sedimentary assemblages, which consist of the same facies association of diamictons, laminated lacustrine deposits and sorted fluvial sediments. Radiocarbon dating of the upper part of the lake sediments sequence (between 12790??85 and 5885??60 14C years b.p.) indicates that the younger sedimentary assemblage was deposited during the last glacial maximum and through early Holocene (Marine Isotope Stage 21, MIS 2-1). Sediment ages obtained for the older assemblage with U/Th and IRSL techniques (between 154.74??22.88 and 129.93??7.90 ka b.p. for selected samples) have large errors but both methods yield results consistent with deposition during the penultimate glacial-interglacial transition (MIS 6-5). Based on analyses of field data combined with glaciological modeling, we argue that both sediment complexes formed due to high sediment productivity spurred by paraglacial conditions with glaciers present in the uplands around the Bovec Basin but not extending down to the basin floor. Our study shows that the extent and intensity of direct glacial sedimentation by Late Quaternary glaciers in the region was previously significantly overestimated. ?? 2004 Elsevier B.V. All rights reserved.

  7. Quaternary pulse position modulation electronics for free-space laser communications

    NASA Technical Reports Server (NTRS)

    Budinger, J. M.; Kerslake, S. D.; Nagy, L. A.; Shalkhauser, M. J.; Soni, N. J.; Cauley, M. A.; Mohamed, J. H.; Stover, J. B.; Romanofsky, R. R.; Lizanich, P. J.

    1991-01-01

    The development of a high data-rate communications electronic subsystem for future application in free-space, direct-detection laser communications is described. The dual channel subsystem uses quaternary pulse position modulation (QPPM) and operates at a throughput of 650 megabits per second. Transmitting functions described include source data multiplexing, channel data multiplexing, and QPPM symbol encoding. Implementation of a prototype version in discrete gallium arsenide logic, radiofrequency components, and microstrip circuitry is presented.

  8. Mathematical and computational aspects of quaternary liquid mixing free energy measurement using light scattering.

    PubMed

    Wahle, Chris W; Ross, David S; Thurston, George M

    2012-07-21

    We provide a mathematical and computational analysis of light scattering measurement of mixing free energies of quaternary isotropic liquids. In previous work, we analyzed mathematical and experimental design considerations for the ternary mixture case [D. Ross, G. Thurston, and C. Lutzer, J. Chem. Phys. 129, 064106 (2008); C. Wahle, D. Ross, and G. Thurston, J. Chem. Phys. 137, 034201 (2012)]. Here, we review and introduce dimension-free general formulations of the fully nonlinear partial differential equation (PDE) and its linearization, a basis for applying the method to composition spaces of any dimension, in principle. With numerical analysis of the PDE as applied to the light scattering implied by a test free energy and dielectric gradient combination, we show that values of the Rayleigh ratio within the quaternary composition tetrahedron can be used to correctly reconstruct the composition dependence of the free energy. We then extend the analysis to the case of a finite number of data points, measured with noise. In this context the linearized PDE describes the relevant diffusion of information from light scattering noise to the free energy. The fully nonlinear PDE creates a special set of curves in the composition tetrahedron, collections of which form characteristics of the nonlinear and linear PDEs, and we show that the information diffusion has a time-like direction along the positive normals to these curves. With use of Monte Carlo simulations of light scattering experiments, we find that for a modest laboratory light scattering setup, about 100-200 samples and 100 s of measurement time are enough to be able to measure the mixing free energy over the entire quaternary composition tetrahedron, to within an L(2) error norm of 10(-3). The present method can help quantify thermodynamics of quaternary isotropic liquid mixtures.

  9. Late Quaternary transgressive large dunes on the sediment-starved Adriatic shelf

    USGS Publications Warehouse

    Correggiari, A.; Field, M.E.; Trincardi, F.

    1996-01-01

    The Adriatic epicontinental basin is a low-gradient shelf where the late-Quaternary transgressive systems tract (TST) is composed of thin parasequences of backbarrier, shoreface and offshore deposits. The facies and internal architecture of the late-Quaternary TST in the Adriatic epicontinental basin changed consistently from early transgression to late transgression reflecting: (1) fluctuations in the balance between sediment supply and accommodation increase, and (2) a progressive intensification of the oceanographic regime, driven by the transgressive widening of the basin to as much as seven times its lowstand extent. One of the consequences of this trend is that high-energy marine bedforms such as sand ridges and sand waves characterize only areas that were flooded close to the end of the late-Quaternary sea-level rise, when the wind fetch was maximum and bigger waves and stronger storm currents could form. We studied the morphology, sediment composition and sequence-stratigraphical setting of a field of asymmetric bedforms (typically 3 m high and 600 m in wavelength) in 20-24 m water depth offshore the Venice Lagoon in the sediment-starved North Adriatic shelf. The sand that forms these large dunes derived from a drowned transgressive coastal deposit reworked by marine processes. Early cementation took place over most of the dune crests limiting their activity and preventing their destruction. Both the formation and deactivation of this field of sand dunes occurred over a short time interval close to the turn-around point that separates the late-Quaternary sea-level rise and the following highstand and reflect rapid changes in the oceanographic regime of the basin.

  10. Electric field dynamics in nitride structures containing quaternary alloy (Al, In, Ga)N

    NASA Astrophysics Data System (ADS)

    Borysiuk, J.; Sakowski, K.; DróŻdŻ, P.; Korona, K. P.; Sobczak, K.; Muziol, G.; Skierbiszewski, C.; Kaminska, A.; Krukowski, S.

    2016-07-01

    Molecular beam epitaxy growth and basic physical properties of quaternary AlInGaN layers, sufficiently thick for construction of electron blocking layers (EBL), embedded in ternary InGaN layers are presented. Transmission electron microscopy (TEM) measurement revealed good crystallographic structure and compositional uniformity of the quaternary layers contained in other nitride layers, which are typical for construction of nitride based devices. The AlInGaN layer was epitaxially compatible to InGaN matrix, strained, and no strain related dislocation creation was observed. The strain penetrated for limited depth, below 3 nm, even for relatively high content of indium (7%). For lower indium content (0.6%), the strain was below the detection limit by TEM strain analysis. The structures containing quaternary AlInGaN layers were studied by time dependent photoluminescence (PL) at different temperatures and excitation powers. It was shown that PL spectra contain three peaks: high energy donor bound exciton peak from the bulk GaN (DX GaN) and the two peaks (A and B) from InGaN layers. No emission from quaternary AlInGaN layers was observed. An accumulation of electrons on the EBL interface in high-In sample and formation of 2D electron gas (2DEG) was detected. The dynamics of 2DEG was studied by time resolved luminescence revealing strong dependence of emission energy on the 2DEG concentration. Theoretical calculations as well as power-dependence and temperature-dependence analysis showed the importance of electric field inside the structure. At the interface, the field was screened by carriers and could be changed by illumination. From these measurements, the dynamics of electric field was described as the discharge of carriers accumulated on the EBL.

  11. An update of Quaternary faults of central and eastern Oregon

    USGS Publications Warehouse

    Weldon, Ray J., II; Fletcher, D.K.; Weldon, E.M.; Scharer, K.M.; McCrory, P.A.

    2002-01-01

    This is the online version of a CD-ROM publication. We have updated the eastern portion of our previous active fault map of Oregon (Pezzopane, Nakata, and Weldon, 1992) as a contribution to the larger USGS effort to produce digital maps of active faults in the Pacific Northwest region. The 1992 fault map has seen wide distribution and has been reproduced in essentially all subsequent compilations of active faults of Oregon. The new map provides a substantial update of known active or suspected active faults east of the Cascades. Improvements in the new map include (1) many newly recognized active faults, (2) a linked ArcInfo map and reference database, (3) more precise locations for previously recognized faults on shaded relief quadrangles generated from USGS 30-m digital elevations models (DEM), (4) more uniform coverage resulting in more consistent grouping of the ages of active faults, and (5) a new category of 'possibly' active faults that share characteristics with known active faults, but have not been studied adequately to assess their activity. The distribution of active faults has not changed substantially from the original Pezzopane, Nakata and Weldon map. Most faults occur in the south-central Basin and Range tectonic province that is located in the backarc portion of the Cascadia subduction margin. These faults occur in zones consisting of numerous short faults with similar rates, ages, and styles of movement. Many active faults strongly correlate with the most active volcanic centers of Oregon, including Newberry Craters and Crater Lake.

  12. Pollen preservation and Quaternary environmental history in the southeastern United States

    SciTech Connect

    Delcourt, P.A.; Delcourt, H.R.

    1980-01-01

    Reconstructions of Quaternary environmental history based upon modern pollen/vegetation/climate calibrations are more tenable if the factors responsible for variation in pollen assemblages are evaluated. Examination of the state of preservation of Quaternary palynomorphs provides quantitative data concerning the degree of information loss due to alteration of pollen assemblages by syndepositional and post-depositional deterioration. The percentage, concentration, and influx values for total indeterminable pollen are useful criteria in providing an objective and quantitative basis for evaluating the comparability of pollen spectra within and between sites. Supporting data concerning sediment particle-size distribution, organic matter content, and concentration, influx, and taxonomic composition of both determinable pollen and plant macrofossils aid in reconstructing past depositional environments. The potential is high for deterioration of pollen in sediments from the southeastern United States, although considerable variation is found in both kind and degree of deterioration between lacustrine and alluvial sites of different ages and in different latitudes. Modern analogs are a basis for late Quaternary environmental reconstructions when pollen deterioration has not significantly biased the information content of fossil pollen assemblages.

  13. Sr-Isotope record of Quaternary marine terraces on the California coast and off Hawaii

    USGS Publications Warehouse

    Ludwig, K. R.; Muhs, D.R.; Simmons, K.R.; Moore, J.G.

    1992-01-01

    Strontium-isotopic ratios of dated corals have been obtained from submerged reefs formed during Quaternary glacial periods off the Hawaiian islands. These data, combined with data from deep-sea sediments, tightly constrain the secular variation of marine 87Sr 86Sr for the past 800,000 yr. Although long-term trends are apparent, no significant (>0.02???), rapid (<100,000 yr) excursions in 87Sr 86Sr were resolved nor did we observe any samples with 87Sr 86Sr greater than that of modern seawater. Strontium in mollusks from elevated marine terraces formed during interglacial periods on the southern California coast show resolvable and consistent variations in 87Sr 86Sr which, when compared to the trend of Quaternary marine 87Sr 86Sr, can be used to infer uplift rates and define approximate ages for the higher terraces. The Sr-isotope age estimates indicate that uplift rates vary among crustal blocks and were not necessarily constant with time. No contrast in Sr-isotopic ratios between similar-age Hawaiian and California fossils was observed, confirming that any change in marine 87Sr 86Sr from glacial to interglacial periods must be small. A realistic appraisal of the potential of Sr-isotope stratigraphy for chronometric applications in the Quaternary suggests that the technique will be limited to relatively coarse distinctions in age. ?? 1992.

  14. Human Dispersals Along the African Rift Valley in the Late Quaternary

    NASA Astrophysics Data System (ADS)

    Tryon, C. A.; Faith, J. T.; Peppe, D. J.

    2014-12-01

    Climate- and tectonic-driven environmental dynamics of the East African Rift System (EARS) during the Quaternary played an important role in the demographic history of early Homo sapiens, including expansions of modern humans across and out of Africa. Human forager population size, geographic range, and behaviors such as hunting strategies and residential mobility likely varied in response to changes in the local and regional environment. Throughout the Quaternary, floral and faunal change was linked at least in part to variations in moisture availability, temperature, and atmospheric CO2, which in addition to uplift and faulting, contributed to the expansion and contraction of a number of large lakes that served as biogeographic barriers to many taxa. This is particularly clear for the Lake Victoria basin, where biogeographic, geological, and paleontological evidence documents repeated expansion and contraction of the ranges of species in response to lake level and vegetation change. Across much of eastern Africa, the topography of the rift facilitated north-south dispersals, the timing of which may have depended in part on the expansion and contraction of the equatorial forest belt. Dispersal potential likely increased during the more arid periods of the late Quaternary, when the roles of lakes and forests as dispersal barriers was reduced and the extent of low net primary productivity dry grasslands increased, the latter requiring large home ranges for human foragers, conditions suitable for range expansions within H. sapiens.

  15. Properties of true quaternary fission of nuclei with allowance for its multistep and sequential character

    SciTech Connect

    Kadmensky, S. G. Titova, L. V.; Bulychev, A. O.

    2015-07-15

    An analysis of basicmechanisms of binary and ternary fission of nuclei led to the conclusion that true ternary and quaternary fission of nuclei has a sequential two-step (three-step) character, where, at the first step, a fissile nucleus emits a third light particle (third and fourth light particles) under shakeup effects associated with a nonadiabatic character of its collective deformation motion, whereupon the residual nucleus undergoes fission to two fission fragments. Owing to this, the formulas derived earlier for the widths with respect to sequential two- and three-step decays of nuclei in constructing the theory of two-step twoproton decays and multistep decays in chains of genetically related nuclei could be used to describe the relative yields and angular and energy distributions of third and fourth light particles emitted in (α, α), (t, t), and (α, t) pairs upon the true quaternary spontaneous fission of {sup 252}Cf and thermal-neutron-induced fission of {sup 235}U and {sup 233}U target nuclei. Mechanisms that explain a sharp decrease in the yield of particles appearing second in time and entering into the composition of light-particle pairs that originate from true quaternary fission of nuclei in relation to the yields of analogous particles in true ternary fission of nuclei are proposed.

  16. [Preparation of magnetic quaternary chitosan salt and its adsorption of methyl orange from water].

    PubMed

    Zhang, Cong-lu; Hu, Xiao-min; Ying, Shi-ying; Wang, Fang

    2013-05-01

    First, quaternary chitosan salts with different substitution degrees were prepared in glycine hydrochloride ([Gly]Cl) ionic liquid. Nano-sized Fe3O4 powder was obtained through chemical co-precipitation method. And then, magnetic quaternary chitosan particles were prepared through inverse suspension cross-linking using Fe3O4 was the nucleus and glutaraldehyde as the cross-linking agent. The influence of different reaction conditions on adsorption was discussed. Adsorption of methyl orange (MO) by magnetic quaternary chitosan particles was studied through the static adsorption method. The results showed that at pH 3.0 and 25 degrees C the adsorption capacity varied from 37.45 mg x g(-1) to 277.5 mg x g(-1) with the MO concentration ranging from 20 mg x L(-1) to 150 mg x L(-1). The adsorption isotherm was fitted to the Freundlich model and the adsorption kinetics was fitted to the pseudo-second order kinetic isotherms capacity experiment. It was found that after the adsorbent was used for four times, its removal rate still exceeded 90%. PMID:23914533

  17. Origin of Bermuda's clay-rich Quaternary paleosols and their paleoclimatic significance

    USGS Publications Warehouse

    Herwitz, S.R.; Muhs, D.R.; Prospero, J.M.; Mahan, S.; Vaughn, B.

    1996-01-01

    Red clayey paleosols that are chiefly the product of aerosolic dust deposition are interbedded in the Quaternary carbonate formations of the Bermuda oceanic island system. These paleosols provide a basis for reconstructing Quaternary atmospheric circulation patterns in the northwestern Atlantic. Geochemical analyses were performed on representative paleosol samples to identify their parent dust source. Fine-grained fractions were analyzed by energy-dispersive X ray fluorescence to determine trace element (Zr, Y, La, Ti, and Nb) concentrations and to derive geochemical signatures based on immobile element ratios. These ratios were compared with geochemical signatures determined for three possible sources of airborne dust: (1) Great Plains loess, (2) Mississippi River Valley loess, and (3) Saharan dust. The Zr/Y and Zr/La ratios provided the clearest distinction between the hypothesized dust sources. The low ratios in the paleosol B horizons most closely resemble Saharan dust in the <2-??m size class fraction. Contributions from the two North American loessial source areas could not be clearly detected. Thus Bermuda paleosols have a predominantly Saharan aerosolic dust signature. Saharan dust deposition on Bermuda during successive Quaternary glacial periods is consistent with patterns of general circulation models, which indicate that during glacial maxima the northeast summer trade winds were stronger than at present and reached latitudes higher than 30 ?? N despite lower-than-present sea surface temperatures in the North Atlantic.

  18. Characterisation of quaternary polymethacrylate films containing tartaric acid, metoprolol free base or metoprolol tartrate.

    PubMed

    Glaessl, B; Siepmann, F; Tucker, I; Siepmann, J; Rades, T

    2009-11-01

    The aim of this study was to better understand the interactions between metoprolol tartrate and quaternary polymethacrylate (Eudragit RL and Eudragit RS) films. For reasons of comparison, polymeric films containing the free base metoprolol or free tartaric acid were also prepared. Systems containing various amounts of the free base, free acid and the salt were characterised using polarising light microscopy, X-ray powder diffraction, differential scanning calorimetry and mechanical analysis (puncture test). The free base is the most efficient plasticiser of the three species for Eudragit RL and Eudragit RS, but with limited solubility in the polymers. Due to its hydrophobicity, it can interact with the hydrophobic polymer backbones. In contrast, in salt containing films, ionic interactions between the positively charged quaternary ammonium groups and the negatively charged tartrate anions apparently occur, this being suggested by the different effects on Eudragit RL versus RS, which have different contents of quaternary ammonium groups. Importantly, the combination of acid and base as a salt avoids drug precipitation at higher metoprolol contents. The obtained new insight into the occurring drug-polymer interactions can help to facilitate the development/optimisation of this type of dosage forms.

  19. Ostracode Mg/Ca Ratios from Quaternary Sediments of the Arctic Ocean

    NASA Astrophysics Data System (ADS)

    Dwyer, G. S.; Caverly, E. K.; Cronin, T. M.; Polyak, L. V.; DeNinno, L.; Rodriguez-Lazaro, J.

    2013-12-01

    We analyzed magnesium/calcium (Mg/Ca) ratios from adult, calcitic shells of the deep-sea ostracode Krithe from the Northwind and Mendeleev Ridges, Arctic Ocean, to reconstruct orbital-scale Quaternary bottom-water temperature history. Results show an early Pleistocene (~1.5 Ma to 500 ka) Mg/CaKrithe pattern with low-amplitude, possibly orbitally controlled, oscillations between 10.5 and 12.5 mmol/mol followed by a progressive trend towards higher ratios (> 17 mmol/mol) during the last 500 ka. This shift coincides with the mid-Pleistocene Transition and mid-Brunhes Event (~ 300-500 ka) recognized in microfaunal proxy records in the Arctic Ocean. Analyses of Mg/CaKrithe from intervals representing marine isotope stage 11 (MIS 11) in 5 cores from water depths from 700 to 1470 m show Mg/Ca ratios ranging from 10.5 to 14 mmol/mol. A 2 mmol/mol excursion in Mg/CaKrithe within MIS 11 seen in all cores likely corresponds to a brief stadial event recognized also in planktic and benthic microfaunas. We will discuss the implications of Mg/Ca paleothermometry for deep Arctic Ocean circulation and the evolution of Arctic sea ice during major Quaternary climatic transitions as well as possible factors other than water temperature that may influence Mg/Ca ratios in Krithe shells from Quaternary sediments from the Arctic Ocean.

  20. Quaternary fluvial response to climate change in glacially influenced river systems

    NASA Astrophysics Data System (ADS)

    Cordier, Stéphane; Adamson, Kathryn; Delmas, Magali; Calvet, Marc; Harmand, Dominique

    2016-04-01

    Over the last few decades, many studies in Europe and other continents have focused on the fluvial response to climate forcing in unglaciated basins. However, glacial activity may have a profound impact on the behaviour of the fluvial systems located downstream. In comparison to ice-free basins, these systems are characterised by distinctive hydrological and sediment supply regimes. Over Quaternary timescales, the fluvial records are influenced by periglacial (in non-glaciated areas), proglacial, and paraglacial processes. Understanding the impacts of these processes on the formation and preservation of the Quaternary geomorphological and sedimentary archives is key for our understanding of glacial-fluvial interactions. We investigate the impact of Quaternary glacial activity on fluvial sediment transfer, deposition, and preservation. Using existing studies from across Europe, we create a database of glaciofluvial geomorphology, sedimentology, and geochronology. This is used to examine how glacial forcing of fluvial systems varies spatially in different basin settings, and temporally over successive Milankovitch cycles. In particular, we focus on the ways in which the primary glacial-fluvial depositional signal could be distinguished from periglacial and paraglacial reworking and redeposition.

  1. Quaternary Geologic Map of the Platte River 4 Degrees x 6 Degrees Quadrangle, United States

    USGS Publications Warehouse

    Swinehart, James B.; Dreeszen, Vincent H.; Richmond, Gerald Martin; Tipton, Merlin J.; Bretz, Richard F.; Steece, Fred V.; Hallberg, George R.; Goebel, Joseph E.; edited and integrated by Richmond, Gerald Martin

    1994-01-01

    The Quaternary Geologic Map of the Platte River 4 degree x 6 degree Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the earth. They make up the 'ground' on which we walk, the 'dirt' in which we dig foundations, and the 'soil' in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale. This map is part of the Quaternary Geologic Atlas of the United States (I-1420). It was first published as a printed edition in 1994. The geologic data have now been captured digitally and are presented here along with images of the printed map sheet and component parts as PDF files.

  2. Quaternary geologic map of the Hatteras 4° x 6° quadrangle, United States

    USGS Publications Warehouse

    State compilations by Johnson, Gerald H.; Richmond, Gerald Martin; edited and integrated by Richmond, G. M.; Fullerton, D.S.; Weide, D.L.; Digital edition by Bush, Charles A.

    1986-01-01

    This map is part of the Quaternary Geologic Atlas of the United States (I-1420). It was first published as a printed edition in 1986. The geologic data have now been captured digitally and are presented here along with images of the printed map sheet and component parts as PDF files. The Quaternary Geologic Map of the Hatteras 4° x 6° Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the Earth. They make up the "ground" on which we walk, the "dirt" in which we dig foundations, and the "soil" in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale.

  3. Seismic evidence of Quaternary faulting in the Benton Hills area, southeast Missouri

    USGS Publications Warehouse

    Palmer, J.R.; Shoemaker, M.; Hoffman, D.; Anderson, N.L.; Vaughn, J.D.; Harrison, R.W.

    1997-01-01

    Two reflection seismic profiles at English Hill, across the southern edge of the Benton Hills escarpment, southeast Missouri, establish that geologic structures at English Hill are of tectonic origin. The lowland area to the south of the escarpment is relatively undisturbed. The geology at English Hill is structurally complex, and reflection seismic and geologic data indicate extensive and episodic faulting of Paleozoic, Cretaceous, Tertiary, and Quaternary strata. The individual faults have near-vertical fault surfaces with maximum vertical separations on the order of 15 m. They appear to be clustered in north-northeast trending zones that essentially parallel one of the dominant Benton Hills structural trends. These observations suggest that previously mapped Quaternary faults at English Hill are deep-seated and tectonic in origin. This paper documents recent faulting at English Hill and is the first time late Quaternary, surface-rupture faulting has been recognized in the middle Mississippi River Valley region outside of the New Madrid seismic zone. This has important implications for earthquake assessment in the midcontinent.

  4. Origin of Bermuda's clay-rich Quaternary paleosols and their paleoclimatic significance

    NASA Astrophysics Data System (ADS)

    Herwitz, Stanley R.; Muhs, Daniel R.; Prospero, Joseph M.; Mahan, Shannon; Vaughn, Bruce

    1996-10-01

    Red clayey paleosols that are chiefly the product of aerosolic dust deposition are interbedded in the Quaternary carbonate formations of the Bermuda oceanic island system. These paleosols provide a basis for reconstructing Quaternary atmospheric circulation patterns in the northwestern Atlantic. Geochemical analyses were performed on representative paleosol samples to identify their parent dust source. Fine-grained fractions were analyzed by energy-dispersive X ray fluorescence to determine trace element (Zr, Y, La, Ti, and Nb) concentrations and to derive geochemical signatures based on immobile element ratios. These ratios were compared with geochemical signatures determined for three possible sources of airborne dust: (1) Great Plains loess, (2) Mississippi River Valley loess, and (3) Saharan dust. The Zr/Y and Zr/La ratios provided the clearest distinction between the hypothesized dust sources. The low ratios in the paleosol B horizons most closely resemble Saharan dust in the <2-μm size class fraction. Contributions from the two North American loessial source areas could not be clearly detected. Thus Bermuda paleosols have a predominantly Saharan aerosolic dust signature. Saharan dust deposition on Bermuda during successive Quaternary glacial periods is consistent with patterns of general circulation models, which indicate that during glacial maxima the northeast summer trade winds were stronger than at present and reached latitudes higher than 30°N despite lower-than-present sea surface temperatures in the North Atlantic.

  5. Quaternary polymethacrylate-magnesium aluminum silicate films: molecular interactions, mechanical properties and tackiness.

    PubMed

    Rongthong, Thitiphorn; Sungthongjeen, Srisagul; Siepmann, Juergen; Pongjanyakul, Thaned

    2013-12-15

    The aim of this study was to investigate the impact of the addition of magnesium aluminum silicate (MAS), a natural clay, on the properties of polymeric films based on quaternary polymethacrylates (QPMs). Two commercially available aqueous QPM dispersions were studied: Eudragit(®) RS 30D and Eudragit(®) RL 30D (the dry copolymers containing 5 and 10% quaternary ammonium groups, respectively). The composite QPM-MAS films were prepared by casting. Importantly, QPM interacted with MAS and formed small flocculates prior to film formation. Continuous films were obtained up to MAS contents of 19% (referred to the QPM dry mass). ATR-FTIR and PXRD revealed that the positively charged quaternary ammonium groups of QPM interacted with negatively charged SiO(-) groups of MAS, creating nanocomposite materials. This interaction led to improved thermal stability of the composite films. The puncture strength and elongation at break of dry systems decreased with increasing MAS content. In contrast, the puncture strength of the wet QPM-MAS films (upon exposure to acidic or neutral media) increased with increasing MAS content. Furthermore, incorporation of MAS into QPM films significantly decreased the latter's tackiness in the dry and wet state. These findings suggest that nanocomposite formation between QPM and MAS in the systems can enhance the strength of wet films and decrease their tackiness. Thus, MAS offers an interesting potential as novel anti-tacking agent for QPM coatings. PMID:24144950

  6. Role of Growth Faulting in the Quaternary Development of Mississippi-River Delta

    NASA Astrophysics Data System (ADS)

    Mohrig, D.; George, T. J.; Straub, K. M.

    2008-12-01

    We use an industry grade seismic volume and observations of present-day surface topography to resolve the influence of growth faulting on evolution of Mississippi delta in southeastern Louisiana from the Pleistocene to Recent. The volume of seismic data covers an area roughly 1400 square kilometers in size and it resolves many normal faults with displacements that can be tied to movement of Jurassic Louann Salt in the subsurface. We have defined the Quaternary activity associated with 6 of these normal faults by measuring the progressive offset of strata deposited on the delta surface over time. These measurements of fault displacement were restricted to the sedimentary section positioned 150 to 1500 m beneath the delta surface. Total vertical offsets measured within this Quaternary section range from 60 to 150 m. These fault displacements represent abrupt spatial variations in subsidence rate that are between 4 and 8 percent of the regional, long-term deposition rate. Our best estimates for the Quaternary rates of fault displacement vary between 0.1 and 1 mm/yr. Five faults can be connected to deformation of the modern delta surface. Wetland on the footwall is replaced by open water on the hanging wall of these structures. In spite of this evidence for modern surface deformation, the orientations of buried, seismically resolved channel bodies do not appear to be affected by the positions of active growth faults. We will evaluate the competition between subsidence and sedimentation patterns that leads to this style of channelized stratigraphy.

  7. Quaternary ammonium salts intercalated α-ZrP compounds for adsorption of phenolic compounds

    NASA Astrophysics Data System (ADS)

    Wang, Hongning; Liu, Wenjin; Yao, Wei; Zhang, Ke; Zhong, Jing; Chen, Ruoyu

    2013-03-01

    By using methylamine as the colloidization agent to weaken the interactions of α-ZrP laminate, the quaternary ammonium salts of DTAB, TTAB, CTAB and STAB were successfully intercalated into the methylamine pre-pillared α-ZrP, denoted as DTAB-ZrP, TTAB-ZrP, CTAB-ZrP and STAB-ZrP, respectively. XRD, FTIR, TEM and N2 sorption were used to characterize the intercalated compounds, and the arrangements of intercalated quaternary ammonium salts within ZrP were supposed according to the results. It was shown that the interlayer distances were increased from 0.76 nm to 2.10-3.50 nm and the intercalated quaternary amine salt cationic bonded with Psbnd O- anion through electrostatic interaction. The phenolic compounds adsorption results have demonstrated that all the four intercalated compounds have good adsorption performance, and CTAB-ZrP show the highest maximum adsorption amounts of 0.90, 1.25 and 1.34 mmol g-1, for phenol, 2-chlorophenol and 2,4-dichlorophenolare, respectively. The adsorption isotherms of phenolic compounds are linear with the C0 of 2.0-6.0 mmol L-1 and fit well to both the Linear and the Freundlich models, which indicated that the adsorption mechanism is mainly partition effects of organic phase within ZrP interlayer.

  8. Quaternary polymethacrylate-magnesium aluminum silicate films: molecular interactions, mechanical properties and tackiness.

    PubMed

    Rongthong, Thitiphorn; Sungthongjeen, Srisagul; Siepmann, Juergen; Pongjanyakul, Thaned

    2013-12-15

    The aim of this study was to investigate the impact of the addition of magnesium aluminum silicate (MAS), a natural clay, on the properties of polymeric films based on quaternary polymethacrylates (QPMs). Two commercially available aqueous QPM dispersions were studied: Eudragit(®) RS 30D and Eudragit(®) RL 30D (the dry copolymers containing 5 and 10% quaternary ammonium groups, respectively). The composite QPM-MAS films were prepared by casting. Importantly, QPM interacted with MAS and formed small flocculates prior to film formation. Continuous films were obtained up to MAS contents of 19% (referred to the QPM dry mass). ATR-FTIR and PXRD revealed that the positively charged quaternary ammonium groups of QPM interacted with negatively charged SiO(-) groups of MAS, creating nanocomposite materials. This interaction led to improved thermal stability of the composite films. The puncture strength and elongation at break of dry systems decreased with increasing MAS content. In contrast, the puncture strength of the wet QPM-MAS films (upon exposure to acidic or neutral media) increased with increasing MAS content. Furthermore, incorporation of MAS into QPM films significantly decreased the latter's tackiness in the dry and wet state. These findings suggest that nanocomposite formation between QPM and MAS in the systems can enhance the strength of wet films and decrease their tackiness. Thus, MAS offers an interesting potential as novel anti-tacking agent for QPM coatings.

  9. Synthesis and application of a quaternary phosphonium polymer coagulant to avoid N-nitrosamine formation.

    PubMed

    Zeng, Teng; Pignatello, Joseph J; Li, Russell Jingxian; Mitch, William A

    2014-11-18

    Quaternary ammonium cationic polymers, such as poly(diallyldimethylammonium chloride) (polyDADMAC) are widely used for coagulating and removing negatively charged particles and dissolved organic matter (DOM) from drinking water. Their use, however, has been linked to the formation of carcinogenic N-nitrosamines as byproducts during chloramine-based drinking water disinfection. In this study, a novel quaternary phosphonium cationic polymer, poly(diallyldiethylphosphonium chloride) (polyDADEPC), was synthesized such that the quaternary nitrogen atom of polyDADMAC was substituted with a phosphorus atom. Formation potential tests revealed that even under strong nitrosation conditions, polyDADEPC and related lower-order P-based compounds formed oxygenated and not nitrosated products. Bench-scale jar tests using three different source waters further demonstrated that polyDADEPC achieved coagulation performance comparable to commercial polyDADMACs for particle and DOM removals within the typical dose range used for drinking water treatment. This work highlights the potential use of a phosphonium coagulant polymer, polyDADEPC, as a viable alternative to polyDADMAC to avoid nitrosated byproduct formation during chloramination. PMID:25322258

  10. New synthetic aliphatic sulfonamido-quaternary ammonium salts as anticancer chemotherapeutic agents.

    PubMed

    Song, Doona; Yang, Jee Sun; Oh, Changmok; Cui, Shuolin; Kim, Bo-Kyung; Won, Misun; Lee, Jang-ik; Kim, Hwan Mook; Han, Gyoonhee

    2013-11-01

    RhoB is expressed during tumor cell proliferation, survival, invasion, and metastasis. In malignant progression, the expression levels of RhoB are commonly attenuated. RhoB is known to be linked to the regulation of the PI3K/Akt survival pathways. Based on aliphatic amido-quaternary ammonium salts that induce apoptosis via up-regulation of RhoB, we synthesized novel aliphatic sulfonamido-quaternary ammonium salts. These new synthetic compounds were evaluated for their biological activities using an in vitro RhoB promoter assay in HeLa cells, and in a growth inhibition assay using human cancer cell lines including PC-3, NUGC-3, MDA-MB-231, ACHN, HCT-15, and NCI-H23. Compound 5b (ethyl-dimethyl-{3-[methyl-(tetradecane-1-sulfonyl)-amino]-propyl}-ammonium; iodide) was the most promising anticancer agent in the series, based upon the potency of growth inhibition and RhoB promotion. These new aliphatic sulfonamido-quaternary ammonium salts could be a valuable series for development of new anticancer chemotherapeutic agents. PMID:24095759

  11. Polarization encoded all-optical quaternary R-S flip-flop using binary latch

    NASA Astrophysics Data System (ADS)

    Chattopadhyay, Tanay; Roy, Jitendra Nath; Chakraborty, Ajoy Kumar

    2009-04-01

    The developments of different multi-valued logic (MVL) systems have received considerable interests in recent years all over the world. In electronics, efforts have already been made to incorporate multi-valued system in logic and arithmetic data processing. But, very little efforts have been given in realization of MVL with optics. In this paper we present novel designs of certain all-optical circuits that can be used for realizing multi-valued logic functions. Polarization encoded all-optical quaternary (4-valued) R-S flip-flop is proposed and described. Two key circuits (all-optical encoder/decoder and a binary latch) are designed first. They are used to realize quaternary flip-flop in all-optical domain. Here the different quaternary logical states are represented by different polarized state of light. Terahertz Optical Asymmetric Demultiplexer (TOAD) based interferometric switch can take an important role. Computer simulation result confirming described methods and conclusion are given in this paper.

  12. Foraminiferal biostratigraphy of the shelf edge: a key to late Quaternary paleoenvironments

    USGS Publications Warehouse

    Poag, C. Wylie; Sidner, B.R.

    1976-01-01

    Foraminiferal assemblages in eight piston cores from West Flower Garden Bank at the edge of the Texas continental shelf contain a nearly complete record of late Quaternary paleoclimatic and geologic events. The faunas are divisible into three distinct successive biofacies on the basis of both planktonic and benthic foraminifers: the basal Inflata Facies accumulated in cool shallow waters during late Pleistocene glaciation; the middle Crassaformis Facies represents a deepening sea that had warming surface waters; the upper Cultrata Facies is characteristic of the Holocene outer-shelf environment. Sea level was at -73 m and -53 m at the end of deposition of the Inflata and Crassaformis Facies, respectively. The biostratigraphic events at West Flower Garden Bank can be accurately correlated with those recorded in the middle and inner shelf and in deep-sea cores. The sequence of late Quaternary sea level and paleotemperature changes in the northern Gulf of Mexico can thereby be reconstructed. Eventually, this knowledge can be integrated with similar data from the shelf edge in other parts of the world to help bridge the gap between the known Quaternary record of the deep sea and that of the continents. ?? 1976.

  13. Quaternary geologic map of the Blue Ridge 4 degrees x 6 degrees quadrangle, United States

    USGS Publications Warehouse

    State compilations by Howard, Alan D.; Behling, Robert E.; Wheeler, Walter H.; Daniels, Raymond B.; Swadley, W.C.; Richmond, Gerald M.; Goldthwait, Richard P.; Sevon, William D.; Miller, Robert A.; Edited and integrated by Richmond, Gerald M.; Fullerton, David S.; Christiansen, Ann Coe; Digital edition by Bush, Charles A.

    1991-01-01

    This map is part of the Quaternary Geologic Atlas of the United States (I-1420). It was first published as a printed edition in 1986. The geologic data have now been captured digitally and are presented here along with images of the printed map sheet and component parts as PDF files. The Quaternary Geologic Map of the Blue Ridge 4° x 6° Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the earth. They make up the "ground" on which we walk, the "dirt" in which we dig foundations, and the "soil" in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale.

  14. New perspectives on quaternary faulting in the southern Walker Lane, Nevada and California

    SciTech Connect

    Reheis, M.C.; Noller, J.S.

    1987-12-31

    A preliminary survey of aerial photographs of the southern Walker Lane began in late 1986. The purpose of this survey is to determine the nature and scope of future studies required to ascertain whether the apparent concentration of Quaternary faults in and near the Nevada Test Site is real or is simply a result of the greater effort invested in mapping Quaternary deposits in that area, and determine whether faults in the southern Walker Lane are active and could produce significant earthquakes. The survey is focused on the area extending south from Lone Mountain to Pahrump Valley and east from the Furnace Creek fault zone to an irregular line passing through the Cactus Range and Pahute Mesa. Lineaments and scraps were identified on stereopairs of black-and-white aerial photographs at scales of 1:80,000 or 1:60,000. The lineaments and and scarps were plotted on 1:24,000- and 1:62,500-scale topographic maps using a PG-2 plotter, and were color-coded according to distinctness and occurrence in Quaternary or Tertiary deposits (age assignments based on appearance in aerial photographs and on existing geologic maps). Additional lineaments identified on the topographic maps were also plotted. Areas of particular interest were selected for more detailed study using larger-scale aerial photographs. Most of the lineaments and scraps identified in the survey, although referred to as faults in this paper, have not been checked in the field. 11 refs., 1 fig.

  15. Properties of true quaternary fission of nuclei with allowance for its multistep and sequential character

    NASA Astrophysics Data System (ADS)

    Kadmensky, S. G.; Titova, L. V.; Bulychev, A. O.

    2015-07-01

    An analysis of basicmechanisms of binary and ternary fission of nuclei led to the conclusion that true ternary and quaternary fission of nuclei has a sequential two-step (three-step) character, where, at the first step, a fissile nucleus emits a third light particle (third and fourth light particles) under shakeup effects associated with a nonadiabatic character of its collective deformation motion, whereupon the residual nucleus undergoes fission to two fission fragments. Owing to this, the formulas derived earlier for the widths with respect to sequential two- and three-step decays of nuclei in constructing the theory of two-step twoproton decays and multistep decays in chains of genetically related nuclei could be used to describe the relative yields and angular and energy distributions of third and fourth light particles emitted in ( α, α), ( t, t), and ( α, t) pairs upon the true quaternary spontaneous fission of 252Cf and thermal-neutron-induced fission of 235U and 233U target nuclei. Mechanisms that explain a sharp decrease in the yield of particles appearing second in time and entering into the composition of light-particle pairs that originate from true quaternary fission of nuclei in relation to the yields of analogous particles in true ternary fission of nuclei are proposed.

  16. Evaluation of Sintering Behaviors of Saprolitic Nickeliferous Laterite Based on Quaternary Basicity

    NASA Astrophysics Data System (ADS)

    Luo, Jun; Li, Guanghui; Rao, Mingjun; Zhang, Yuanbo; Peng, Zhiwei; Zhi, Qian; Jiang, Tao

    2015-09-01

    The sintering behaviors of saprolitic nickeliferous laterite with various quaternary basicities [(CaO + MgO)/(SiO2 + Al2O3) mass ratio] in a reductive atmosphere are investigated by simulative sintering and validated by sintering pot tests. The simulative sintering results show that the generation of diopside (CaMgSi2O6) with low melting point is the key reason for the decrease in characteristic fusion temperatures when the quaternary basicity increases from 0.5 to 0.8-1.0. Continuous increase of basicity leads to transformation of diopside (CaMgSi2O6) into akermanite (Ca2MgSi2O7), which adversely increases the characteristic fusion temperatures. These findings are confirmed by the sinter pot tests, which demonstrate that the sintering indexes including vertical sintering velocity (VSV), yield ( Y), and productivity ( P), can be improved by optimizing quaternary basicity. At basicity of 1.0, the VSV, Y, P, and ISO tumbling index reach 49.2 mm/min, 80.5%, 1.0 t/(h m2), and 66.5%, respectively.

  17. Quaternary Geologic Map of the Des Moines 4 Degrees x 6 Degrees Quadrangle, United States

    USGS Publications Warehouse

    Hallberg, George R.; Lineback, Jerry A.; Mickelson, David M.; Knox, James C.; Goebel, Joseph E.; Hobbs, Howard C.; Whitfield, John W.; Ward, Ronald A.; Boellstorff, John D.; Swinehart, James B.; Dreeszen, Vincent H.; edited and integrated by Richmond, Gerald Martin; Fullerton, David S.; Christiansen, Ann Coe

    1994-01-01

    The Quaternary Geologic Map of the Des Moines 4 degree x 6 degree Quadrangle was mapped as part of the Quaternary Geologic Atlas of the United States. The atlas was begun as an effort to depict the areal distribution of surficial geologic deposits and other materials that accumulated or formed during the past 2+ million years, the period that includes all activities of the human species. These materials are at the surface of the earth. They make up the 'ground' on which we walk, the 'dirt' in which we dig foundations, and the 'soil' in which we grow crops. Most of our human activity is related in one way or another to these surface materials that are referred to collectively by many geologists as regolith, the mantle of fragmental and generally unconsolidated material that overlies the bedrock foundation of the continent. The maps were compiled at 1:1,000,000 scale. This map is part of the Quaternary Geologic Atlas of the United States (I-1420). It was first published as a printed edition in 1994. The geologic data have now been captured digitally and are presented here along with images of the printed map sheet and component parts as PDF files.

  18. Syntheses, structures, physical and electronic properties of quaternary semiconductors: Cs[RE9Cd4Se18] (RE = Tb-Tm).

    PubMed

    Lin, Hua; Chen, Hong; Liu, Peng-Fei; Yu, Ju-Song; Zheng, Yu-Jun; Ali, Khan Muhammad; Chen, Ling; Wu, Li-Ming

    2016-04-01

    Five new quaternary rare-earth selenides, Cs[RE9Cd4Se18] (RE = Tb-Tm), which are the first examples with closed cavities in the quaternary A/RE/Cd/Q (A = alkali metal; RE = rare earth metal; Q = chalcogenide) system, have been synthesized by high-temperature solid state reactions with a modified reactive CsCl flux. Single crystal X-ray diffraction analyses show that these isostructural materials adopted a known BaV13O18-structure type in the trigonal space group R3[combining macron] (no. 148) with cell parameters of a = 17.773(2)-17.489(6) Å, c = 9.918(2)-9.765(5) Å and Z = 3. The structure is composed of MSe6 (centered by disordered RE and Cd) and RESe6 octahedra that share edges to form a 3D framework, inside which the cuboctahedral Se12 closed cavities accommodate Cs cations. It is interesting to note that these compounds exhibit atomic distributions different from the recently reported Mn-compounds Cs[RE9Mn4Se18]. In Cd-compounds, Cd and RE atoms are statistically mixed only at one of the 18f sites; the rest of the RE atoms are fully occupied at the two framework sites: 18f and 3a. Moreover, the theoretical studies have greatly aided the understanding of the site-preference about a Cd atom in the 3D framework. The synthesis, structural characterization, electronic band structure as well as physical properties of the title compounds are also discussed. PMID:26936600

  19. The Lathrop Wells Volcanic Center: Status of field and geochronology studies

    NASA Astrophysics Data System (ADS)

    Crowe, B.; Morley, R.; Wells, S.; Geissman, J.; McDonald, E.; McFadden, L.; Perry, F.

    The Lathrop Wells volcanic center is located 20 km south of the potential Yucca Mountain site, at the south end of the Yucca Mountain range. It has long been recognized as the youngest basalt center in the region. However, determination of the age and eruptive history of the center has proven problematic. The purpose of this paper is to describe the status of field and geochronology studies of the Lathrop Wells center. Our perspective is that it is critical to assess all possible methods for obtaining cross-checking data to resolve chronology and field problems. It is equally important to consider application of the range of chronology methods available in Quaternary geologic research. Such an approach seeks to increase the confidence in data interpretations through obtaining convergence among separate isotopic, radiogenic, and age-correlated methods. Finally, the assumptions, strengths, and weaknesses of each dating method need to be carefully described to facilitate an impartial evaluation of results.

  20. The Lathrop Wells volcanic center: Status of field and geochronology studies

    SciTech Connect

    Crowe, B.; Morley, R.; Wells, S.; Geissman, J.; McDonald, E.; McFadden, L.; Perry, F.; Murrell, M.; Poths, J.; Forman, S.

    1993-03-01

    The Lathrop Wells volcanic center is located 20 km south of the potential Yucca Mountain site, at the south end of the Yucca Mountain range. It has long been recognized as the youngest basalt center in the region. However, determination of the age and eruptive history of the center has proven problematic. The purpose of this paper is to describe the status of field and geochronology studies of the Lathrop Wells center. Our perspective is that it is critical to assess all possible methods for obtaining cross-checking data to resolve chronology and field problems. It is equally important to consider application of the range of chronology methods available in Quaternary geologic research. Such an approach seeks to increase the confidence in data interpretations through obtaining convergence among separate isotopic, radiogenic, and age-correlated methods. Finally, the assumptions, strengths, and weaknesses of each dating method need to be carefully described to facilitate an impartial evaluation of results.

  1. Using Quaternary fluvial terraces as structural indicators of magma body-related uplift, Socorro, NM

    NASA Astrophysics Data System (ADS)

    Sion, B. D.; Phillips, F. M.; Axen, G. J.; Harrison, B.

    2013-12-01

    The Socorro Magma Body (SMB) is a deep (~19 km) partly molten sill ~100-150 m thick with an area of ~3400 square kilometers beneath Socorro, NM. It causes domal surface uplift of 0 to ~2.5 mm/yr over a diameter of ~60 km. The age and history of the SMB are poorly known, but thermal modeling suggests an age < 1 ka. Over the time span of geodetic data (1911-2013), at current maximum rates, ~25 cm of uplift is expected. Several arguments suggest that the SMB may be significantly older than ~1 ka. If so, terraces of the Rio Grande and major tributaries may record lateral elevation gradients and differential tilting. Terrace deformation over the SMB is complicated by active N-S striking normal faults. Terrace elevations are taken from a commercial, airborne radar-based DEM with ~0.5-1 m of point-to-point scatter, projected to a valley-center line and smoothed using a moving average approach, resulting in ~1 m precision. Deformed terraces of the Rio Salado suggest the SMB is older than ~1 ka. The Rio Salado is a major E-flowing tributary ~25 km north of Socorro, that crosses the N flank of the uplift (rates of 1.0-2.0 mm/yr) and three Quaternary fault zones. Five Middle(?) Pleistocene to Holocene terrace levels are preserved in a 17-km alluvial reach W of the confluence with the Rio Grande. The lowest terrace (Qtb) is ~0.5-3 m above the streambed and is degraded in most areas. No deflection is apparent in Qtb. Older, higher terraces (~17m Qtc; 30 m Qte; 60 m Qtf; and 90 m Qtg) are cut by the E-down Loma Blanca fault and are W-tilted and offset as expected. Qtc, however, is E-tilted over the E flank of the uplift (E-ward change in uplift of ~ -0.4 mm/yr) and merges E-ward with Qtb, consistent with an episode of inflation older than Qtb but younger than Qtc. This tilting cannot be explained by slip on the older W-down Cliff fault, which is overlapped by Qte. Qte is tentatively correlated with the 122 × 18 ka "airport surface". A constant long-term slip rate approach

  2. Map and Data for Quaternary Faults and Fault Systems on the Island of Hawai`i

    USGS Publications Warehouse

    Cannon, Eric C.; Burgmann, Roland; Crone, Anthony J.; Machette, Michael N.; Dart, Richard L.

    2007-01-01

    Introduction This report and digitally prepared, GIS-based map is one of a series of similar products covering individual states or regions of United States that show the locations, ages, and activity rates of major earthquake-related features such as faults and fault-related folds. It is part of a continuing the effort to compile a comprehensive Quaternary fault and fold map and database for the United States, which is supported by the U.S. Geological Survey's (USGS) Earthquake Hazards Program. Guidelines for the compilation of the Quaternary fault and fold maps for the United States were published by Haller and others (1993) at the onset of this project. This compilation of Quaternary surface faulting and folding in Hawai`i is one of several similar state and regional compilations that were planned for the United States. Reports published to date include West Texas (Collins and others, 1996), New Mexico (Machette and others, 1998), Arizona (Pearthree, 1998), Colorado (Widmann and others, 1998), Montana (Stickney and others, 2000), Idaho (Haller and others, 2005), and Washington (Lidke and others, 2003). Reports for other states such as California and Alaska are still in preparation. The primary intention of this compilation is to aid in seismic-hazard evaluations. The report contains detailed information on the location and style of faulting, the time of most recent movement, and assigns each feature to a slip-rate category (as a proxy for fault activity). It also contains the name and affiliation of the compiler, date of compilation, geographic and other paleoseismologic parameters, as well as an extensive set of references for each feature. The map (plate 1) shows faults, volcanic rift zones, and lineaments that show evidence of Quaternary surface movement related to faulting, including data on the time of most recent movement, sense of movement, slip rate, and continuity of surface expression. This compilation is presented as a digitally prepared map product

  3. Reconstructing late Quaternary deep-water masses in the eastern Arctic Ocean using benthonic Ostracoda

    USGS Publications Warehouse

    Jones, R. Ll; Whatley, R.C.; Cronin, T. M.; Dowsett, H.J.

    1999-01-01

    The distribution of Ostracoda in three long cores from the deep eastern Arctic Ocean was studied to determine the palaeoceanographical history of the Eurasian Basin during the late Quaternary. The samples for this study were obtained from the Lomonosov Ridge, Morris Jesup Rise and Yermak Plateau during the Arctic 91 expedition. Ostracoda previously studied in coretops at the same sites as the present study have shown that individual species have a strong association with different water masses and bathymetry. Throughout the late Quaternary, cores exhibit ostracod-rich layers separated by barren intervals. On the basis of biostratigraphical, isotopic and palaeomagnetic data the fossiliferous levels are interpreted as representing interglacial stages. The twenty most significant species were selected for subsequent quantitative investigation using Cluster and Factor analyses, in order to determine similarity and variance between the assemblages. An additional statistical method employing Modern Analogues and the Squared Chord Distance dissimilarity coefficient was utilized to compare the present late Quaternary fossil samples with a modern Arctic database. The results reveal a major faunal division within the Arctic Ocean Deep Water (AODW). Highly abundant and diverse assemblages within the cores were found to group and have good analogues with the Recent bathyal depth (1000-2500 m) upper AODW assemblages. Conversely, assemblages with low abundance and diversity correlate well with abyssal depth (> 3000 m) lower AODW assemblages. The palaeoceanographical history is complicated by the influence of adjacent water masses such as Canada Basin Deep Water (CBDW), Greenland Sea Deep Water (GSDW) and most importantly, Arctic Intermediate Water (AIW), which all had an influence on the ostracod assemblages during the late Quaternary. An enhanced flow of warm saline AIW into the Eurasian Basin results in species-rich upper AODW assemblages having good analogues down to 2750 m

  4. Quaternary geologic map of the Winnipeg 4 degrees x 6 degrees quadrangle, United States and Canada

    USGS Publications Warehouse

    Fullerton, D. S.; Ringrose, S.M.; Clayton, Lee; Schreiner, B.T.; Goebel, J.E.

    2000-01-01

    The Quaternary Geologic Map of the Winnipeg 4? ? 6? Quadrangle, United States and Canada, is a component of the U.S. Geological Survey Quaternary Geologic Atlas of the United States map series (Miscellaneous Investigations Series I-1420), an effort to produce 4? ? 6? Quaternary geologic maps, at 1:1 million scale, of the entire conterminous United States and adjacent Canada. The map and the accompanying text and supplemental illustrations provide a regional overview of the areal distributions and characteristics of surficial deposits and materials of Quaternary age (~1.8 Ma to present) in parts of North Dakota, Minnesota, Manitoba, and Saskatchewan. The map is not a map of soils as soils are recognized in agriculture. Rather, it is a map of soils as recognized in engineering geology, or of substrata or parent materials in which agricultural soils are formed. The map units are distinguished chiefly on the basis of (1)genesis (processes of origin) or environments of deposition: for example, sediments deposited primarily by glacial ice (glacial deposits or till), sediments deposited in lakes (lacustrine deposits), or sediments deposited by wind (eolian deposits); (2) age: for example, how long ago the deposits accumulated; (3) texture (grain size)of the deposits or materials; (4) composition (particle lithology) of the deposits or materials; (5) thickness; and (6) other physical, chemical, and engineering properties. Supplemental illustrations show (1) temporal correlation of the map units, (2) the areal relationships of late Wisconsin glacial ice lobes and sublobes, (3) temporal and spatial correlation of late Wisconsin glacial phases, readvance limits, and ice margin stillstands, (4) temporal and stratigraphic correlation of surface and subsurface glacial deposits in the Winnipeg quadrangle and in adjacent 4? ? 6? quadrangles, and (5) responsibility for state and province compilations. The database provides information related to geologic hazards (for example

  5. The New ILP Database of Quaternary Faults and Folds in South America

    NASA Astrophysics Data System (ADS)

    Costa, C. H.; Cisneros, H. A.; Machette, M. N.; Dart, R. L.

    2003-12-01

    As part of the International Lithosphere Program's Task Group II-2, we have completed the compilation of Quaternary faults and folds in South America and have established an Internet website for this data. The underpinning maps and reports have been released as electronic U.S. Geological Survey Open-File Reports (pdfs, see poster). The maps show the location, time, sense of slip, and activity rate of major earthquake-related features such as faults and fault-related folds. The maps are accompanied by descriptions of their Quaternary activity. The primary elements of the 10-year project are supervision and interpretation of geologic/tectonic information (Costa and Machette), data compilation (project participants), database design and management (Cisneros), and GIS input and management (Dart). A dozen experts in Quaternary faulting, neotectonics, paleoseismology, and seismology compiled the data: questions about individual faults or additions to the database should be directed to them. Prior to this project, digital maps of Quaternary faults did not exist for any of the South America countries, even though understanding the extent and character of active and older Quaternary faults are critical elements of seismic-hazards analysis. These new data will help extend the relatively short record of instrumental and felt seismicity that is the primary parameter for current seismic-hazard assessments in South American countries. Although some fault data were available for most of the countries (i.e., Venezuela), the degree of completeness varies as a function of the remoteness and vegetation cover (i.e., Brazil). A few faults such as the Bocono have had detailed investigations involving modern paleoseismic techniques. Other faults have been studied in some detail, usually in association with concerns about hazards to urban areas or the safety of critical facilities such as mining operations, oil-and-gas pipelines, or power-generating facilities. However, the general state

  6. Plio-Quaternary tectonic evolution off Al Hoceima, Moroccan Margin of the Alboran Basin.

    NASA Astrophysics Data System (ADS)

    Lafosse, Manfred; d'Acremont, Elia; Rabaute, Alain; Mercier de Lépinay, Bernard; Gorini, Christian; Ammar, Abdellah; Tahayt, Abdelilah

    2015-04-01

    We use data from a compilation of industrial and academic 2D surveys and recent data from MARLBORO-1 (2011), MARLBORO-2 (2012), and SARAS (2012) surveys, which provide high resolution bathymetry and 2D seismic reflexion data. We focus on the key area located south of the Alboran Ridge and the Tofiño Bank, and encompassing the Nekor and Boudinar onshore-offshore basins on the Moroccan side of the Alboran Sea. The Nekor basin is a present pull-apart basin in relay between inherited N050° sinistral strike-slip faults. We consider that these faults define the Principal Displacement Zones (PDZ). The northern PDZ marks the position of the crustal Bokkoya fault, which is connected to the Al-Idrisi Fault Zone en relais with the Adra and Carboneras Fault Zones. On the seabed, right-stepping non-coalescent faults characterize the sinistral kinematics of the northern PDZ and give a general N050° azimuth for the crustal discontinuity. The southern PDZ corresponds to the Nekor fault Zone, a Miocene sinistral strike-slip fault acting as the structural limit of the External Rif. On its eastern edge, the Nekor basin is bounded by the N-S onshore-offshore Trougout fault, connecting the northern and the southern PDZ. The western boundary of the Nekor basin is marked by the Rouadi and El-Hammam Quaternary active N-S normal faults. In the offshore Nekor basin, recent N155° conjugated normal faults affect the seabed. Further east, the Boudinar basin is a Plio-Quaternary uplifted Neogene basin. The northeastern segment of the Nekor fault bounds this basin to the south but is inactive in the Quaternary. Normal east-dipping N150° faults are visible offshore in the continuity of the Boudinar fault. From our perspective, the orientation of major tectonic structures (Bokkoya, Nekor and Carboneras faults and the Alboran ridge) under the present compressive regime due to the Europe/Africa convergence is not compatible with a strike-slip motion. The orientation of the most recent Plio-Quaternary

  7. Aminostratigraphy of surface and subsurface Quaternary sediments, North Carolina coastal plain, USA

    USGS Publications Warehouse

    Wehmiller, J. F.; Thieler, E.R.; Miller, D.; Pellerito, V.; Bakeman, Keeney V.; Riggs, S.R.; Culver, S.; Mallinson, D.; Farrell, K.M.; York, L.L.; Pierson, J.; Parham, P.R.

    2010-01-01

    The Quaternary stratigraphy and geochronology of the Albemarle Embayment of the North Carolina (NC) Coastal Plain is examined using amino acid racemization (AAR) in marine mollusks, in combination with geophysical, lithologic, and biostratigraphic analysis of 28 rotasonic cores drilled between 2002 and 2006. The Albemarle Embayment is bounded by structural highs to the north and south, and Quaternary strata thin westward toward the Suffolk paleoshoreline, frequently referred to as the Suffolk Scarp. The Quaternary section is up to ???90. m thick, consists of a variety of estuarine, shelf, back-barrier, and lagoonal deposits, and has been influenced by multiple sea-level cycles. The temporal resolution of the amino acid racemization method is tested statistically and with the stratigraphic control provided by this geologic framework, and it is then applied to the correlation and age estimation of subsurface units throughout the region. Over 500 specimens (primarily Mercenaria and Mulinia) from the subsurface section have been analyzed using either gas chromatographic (GC) or reverse-phase liquid chromatographic (RPLC) techniques. The subsurface stratigraphic data are compared with AAR results from numerous natural or excavated exposures from the surrounding region, as well as results from NC beach collections, to develop a comprehensive aminostratigraphic database for the entire Quaternary record within the NC coastal system. Age mixing, recognized in the beach collections, is also seen in subsurface sections, usually where major seismic reflections or core lithology indicate the presence of stratigraphic discontinuities. Kinetic models for racemization are tested within the regional stratigraphic framework, using either radiocarbon or U-series calibrations or comparison with regional biostratigraphy. Three major Pleistocene aminozones [AZ2, AZ3, and AZ4] are found throughout the region, all being found in superposition in several cores. Each can be subdivided

  8. The Quaternary volcanic rocks of the northern Afar Depression (northern Ethiopia): Perspectives on petrology, geochemistry, and tectonics

    NASA Astrophysics Data System (ADS)

    Hagos, Miruts; Koeberl, Christian; van Wyk de Vries, Benjamin

    2016-05-01

    The northern Afar Depression is one of the most volcano-tectonically active parts of the East African Rift system, a place where oceanic rifting may be beginning to form an incipient oceanic crust. In its center, over an area that is ∼80 km long and ∼50 km wide, there are seven major NNW-SSE-aligned shield volcanoes/volcanic edifices surrounded by compositionally distinct fissure-fed basalts. The Quaternary lavas in this area range from transitional to tholeiitic basalts, with significant across-axis variation both in mineralogy and chemistry. The variation in the contents of the major elements (TiO2, Al2O3, and Fe2O3), incompatible trace elements (Nd, Hf, Th, Ta), and the contents and ratios of the rare earth elements (REE) (e.g., (La/Yb)n = 5.3-8.9) indicate some variation in the petrogenetic processes responsible for the formation of these basalts. However, the variation in isotopic compositions of the mafic lavas is minimal (87Sr/86Sr = 0.7036-0.7041, 143Nd/144Nd = 0.51286-0.51289), which suggests only one source for all the Danakil Depression basalts. These basalts have isotope and incompatible trace element ratios that overlap with those of the Oligocene High-Ti2 flood basalts from the Ethiopian Plateau, interpreted as being derived from the last phase/tail of the Afar mantle plume source. Moreover, the Ce/Pb, Ba/U ratios indicate that the involvement of continental crust in the petrogenesis of the basaltic rocks is minimal; instead, both depth and degree of melting of the source reservoir underneath the northern Afar Depression played a major role for the production of incompatible element-enriched basalts (e.g., AleBagu Shield basalts) and the incompatible element-depleted tholeiitic basalts (e.g., Erta'Ale and Alu Shield basalts).

  9. NIST Diffusion Data Center

    National Institute of Standards and Technology Data Gateway

    NIST Diffusion Data Center (Web, free access)   The NIST Diffusion Data Center is a collection of over 14,100 international papers, theses, and government reports on diffusion published before 1980.

  10. Taking Center Stage.

    ERIC Educational Resources Information Center

    Cohen, Andrew

    1995-01-01

    Describes Ohio's 390,000 square-foot Perry High School and Community Fitness Center and its ability to accommodate all segments of both school and community group activities. A list of companies that supply the center is included. (GR)

  11. Tornadoes: A Center Approach.

    ERIC Educational Resources Information Center

    Christman-Rothlein, Liz; Meinbach, Anita M.

    1981-01-01

    Information is given on how to put together a learning center. Discusses information and activity packets for a complete learning center on tornadoes including objectives, directions, materials, photographs of physical arrangements, and posttest. (DC)

  12. Evaluating Teacher Centers

    ERIC Educational Resources Information Center

    Feiman, Sharon

    1977-01-01

    Considers what teacher centers actually are, what they do, what they are supposed to do, and how they are formed. Discusses three types of centers, their organizational structure and function, and the theory underlying them. (Editor/RK)

  13. National Health Information Center

    MedlinePlus

    ... About ODPHP Dietary Guidelines Physical Activity Guidelines Health Literacy and Communication Health Care Quality and Patient Safety Healthy People healthfinder health.gov About ODPHP National Health Information Center National Health Information Center The National Health ...

  14. BKG Data Center

    NASA Technical Reports Server (NTRS)

    Thorandt, Volkmar; Wojdziak, Reiner

    2013-01-01

    This report summarizes the activities and background information of the IVS Data Center for the year 2012. Included is information about functions, structure, technical equipment, and staff members of the BKG Data Center.

  15. ACTS data center

    NASA Technical Reports Server (NTRS)

    Syed, Ali; Vogel, Wolfhard J.

    1993-01-01

    Viewgraphs on ACTS Data Center status report are included. Topics covered include: ACTS Data Center Functions; data flow overview; PPD flow; RAW data flow; data compression; PPD distribution; RAW Data Archival; PPD Audit; and data analysis.

  16. Nonschool Learning Center

    ERIC Educational Resources Information Center

    Brown, Doris B.

    1972-01-01

    Describes a privately financed science center, museum and planetarium - observatory in Twin Falls, Idaho. Centers three hour program includes a lecture on archaeology, time to look at displays, a lunch break, and a planetarium lecture. (RB)

  17. Accredited Birth Centers

    MedlinePlus

    ... Birth Center Accredited 624 Smith Avenue St. Paul, MN 55107 651-689-3988 Accredited since April 2015 ... Birth Center Accredited 1901 44th Avenue North Minneapolis, MN 55343 612-338-2784 Accredited since November 2015 ...

  18. Regional Instrumentation Centers.

    ERIC Educational Resources Information Center

    Cromie, William J.

    1980-01-01

    Focuses on the activities of regional instrumentation centers that utilize the state-of-the-art instruments and methodology in basic scientific research. The emphasis is on the centers involved in mass spectroscopy, magnetic resonance spectroscopy, lasers, and accelerators. (SA)

  19. The Quaternary Silver Creek Fault Beneath the Santa Clara Valley, California

    USGS Publications Warehouse

    Wentworth, Carl M.; Williams, Robert A.; Jachens, Robert C.; Graymer, Russell W.; Stephenson, William J.

    2010-01-01

    The northwest-trending Silver Creek Fault is a 40-km-long strike-slip fault in the eastern Santa Clara Valley, California, that has exhibited different behaviors within a changing San Andreas Fault system over the past 10-15 Ma. Quaternary alluvium several hundred meters thick that buries the northern half of the Silver Creek Fault, and that has been sampled by drilling and imaged in a detailed seismic reflection profile, provides a record of the Quaternary history of the fault. We assemble evidence from areal geology, stratigraphy, paleomagnetics, ground-water hydrology, potential-field geophysics, and reflection and earthquake seismology to determine the long history of the fault in order to evaluate its current behavior. The fault formed in the Miocene more than 100 km to the southeast, as the southwestern fault in a 5-km-wide right step to the Hayward Fault, within which the 40-km-long Evergreen pull-apart basin formed. Later, this basin was obliquely cut by the newly recognized Mt. Misery Fault to form a more direct connection to the Hayward Fault, although continued growth of the basin was sufficient to accommodate at least some late Pliocene alluvium. Large offset along the San Andreas-Calaveras-Mt Misery-Hayward Faults carried the basin northwestward almost to its present position when, about 2 Ma, the fault system was reorganized. This led to near abandonment of the faults bounding the pull-apart basin in favor of right slip extending the Calaveras Fault farther north before stepping west to the Hayward Fault, as it does today. Despite these changes, the Silver Creek Fault experienced a further 200 m of dip slip in the early Quaternary, from which we infer an associated 1.6 km or so of right slip, based on the ratio of the 40-km length of the strike-slip fault to a 5-km depth of the Evergreen Basin. This dip slip ends at a mid-Quaternary unconformity, above which the upper 300 m of alluvial cover exhibits a structural sag at the fault that we interpret as

  20. Origin, Extent, and Thickness of Quaternary Geologic Units in the Willamette Valley, Oregon

    USGS Publications Warehouse

    O'Connor, Jim E.; Sarna-Wojcicki, Andrei M.; Wozniak, Karl C.; Polette, Danial J.; Fleck, Robert J.

    2001-01-01

    Stratigraphic and chronologic information collected for Quaternary deposits in the Willamette Valley, Oregon, provides a revised stratigraphic framework that serves as a basis for a 1:250,000-scale map, as well as for thickness estimates of widespread Quaternary geologic units. We have mapped 11 separate Quaternary units that are differentiated on the basis of stratigraphic, topographic, pedogenic, and hydrogeologic properties. In summation, these units reflect four distinct episodes in the Quaternary geologic development of the Willamette Valley: 1) Fluvial sands and gravels that underlie terraces flanking lowland margins and tributary valleys were probably deposited between 2.5 and 0.5 million years ago. They are the oldest widespread surficial Quaternary deposits in the valley. Their present positions and preservation are undoubtedly due to postdepositional tectonic deformation - either by direct tectonic uplift of valley margins, or by regional tectonic controls on local base level. 2) Tertiary and Quaternary excavation or tectonic lowering of the Willamette Valley accommodated as much as 500 m (meters) of lacustrine and fluvial fill. Beneath the lowland floor, much of the upper 10 to 50 m of fill is Quaternary sand and gravel deposited by braided channel systems in subhorizontal sheets 2 to 10 m thick. These deposits grade to gravel fans 40 to 100 m thick where major Cascade Range rivers enter the valley and are traced farther upstream as much thinner valley trains of coarse gravel. The sand and gravel deposits have ages that range from greater than 420,000 to about 12,000 years old. A widely distributed layer of sand and gravel deposited at about 12 ka (kiloannum, thousands of years before the present) is looser and probably more permeable than older sand and gravel. Stratigraphic exposures and drillers' logs indicate that this late Pleistocene unit is mostly between 5 and 20 m thick where it has not been subsequently eroded by the Willamette River and its

  1. Teachers' Centers Exchange Directory.

    ERIC Educational Resources Information Center

    Lance, Jeanne; Kreitzman, Ruth

    This directory has three major sections. The foreword is a brief essay describing the purpose of the Teachers' Centers Exchange, the "network" of teachers' centers, and the reasons for compiling and publishing this directory. The second section gives descriptions of 78 teachers' centers in the Exchange's network. These descriptions highlight each…

  2. Data center cooling method

    DOEpatents

    Chainer, Timothy J.; Dang, Hien P.; Parida, Pritish R.; Schultz, Mark D.; Sharma, Arun

    2015-08-11

    A method aspect for removing heat from a data center may use liquid coolant cooled without vapor compression refrigeration on a liquid cooled information technology equipment rack. The method may also include regulating liquid coolant flow to the data center through a range of liquid coolant flow values with a controller-apparatus based upon information technology equipment temperature threshold of the data center.

  3. Center of buoyancy definition

    SciTech Connect

    Sandberg, V.

    1988-12-01

    The center of buoyancy of an arbitrary shaped body is defined in analogy to the center of gravity. The definitions of the buoyant force and center of buoyancy in terms of integrals over the area of the body are converted to volume integrals and shown to have simple intuitive interpretations.

  4. Equality of Fitness Centers

    ERIC Educational Resources Information Center

    Swoyer, Jesse O.

    2008-01-01

    The author, who has been a personal trainer for the past ten years, recently realized that all fitness centers are not equal. In February, he was able to participate in the grand opening of the Center for Independent Living of Central PA (CILCP), a fitness center that is designed to accommodate persons with disabilities living in the Central…

  5. Data Center Tasking.

    ERIC Educational Resources Information Center

    Temares, M. Lewis; Lutheran, Joseph A.

    Operations tasking for data center management is discussed. The original and revised organizational structures of the data center at the University of Miami are also described. The organizational strategy addresses the functions that should be performed by the data center, anticipates the specialized skills required, and addresses personnel…

  6. Language Resource Centers Program

    ERIC Educational Resources Information Center

    Office of Postsecondary Education, US Department of Education, 2012

    2012-01-01

    The Language Resource Centers (LRC) program provides grants to institutions of higher education to establish, strengthen, and operate resource centers that serve to improve the nation's capacity to teach and learn foreign languages. Eligible applicants are institutions of higher education. Duration of the grant is four years. Center activities…

  7. Nuclear Reaction Data Centers

    SciTech Connect

    McLane, V.; Nordborg, C.; Lemmel, H.D.; Manokhin, V.N.

    1988-01-01

    The cooperating Nuclear Reaction Data Centers are involved in the compilation and exchange of nuclear reaction data for incident neutrons, charged particles and photons. Individual centers may also have services in other areas, e.g., evaluated data, nuclear structure and decay data, reactor physics, nuclear safety; some of this information may also be exchanged between interested centers. 20 refs., 1 tab.

  8. THE INSTRUCTIONAL MATERIALS CENTER.

    ERIC Educational Resources Information Center

    ARTZ, DELPHINE; AND OTHERS

    THIS BULLETIN PRESENTS RECOMMENDATIONS WITH REGARD TO PROGRAM, PERSONNEL, AND FACILITIES FOR AN INSTRUCTIONAL MATERIALS CENTER. IT INCLUDES UTILIZATION, MATERIALS, FACILITIES, ORGANIZATION AND LAYOUTS FOR AN INSTRUCTIONAL MATERIALS CENTER. CASE STUDIES AND EXAMPLES ARE PROVIDED FOR MAKING THE MAXIMUM POSSIBLE USAGE OF THE CENTER WITHIN BOTH THE…

  9. A call center primer.

    PubMed

    Durr, W

    1998-01-01

    Call centers are strategically and tactically important to many industries, including the healthcare industry. Call centers play a key role in acquiring and retaining customers. The ability to deliver high-quality and timely customer service without much expense is the basis for the proliferation and expansion of call centers. Call centers are unique blends of people and technology, where performance indicates combining appropriate technology tools with sound management practices built on key operational data. While the technology is fascinating, the people working in call centers and the skill of the management team ultimately make a difference to their companies. PMID:10182518

  10. Emmons Lake Volcanic Center, Alaska Peninsula: Source of the Late Wisconsin Dawson tephra, Yukon Territory, Canada

    USGS Publications Warehouse

    Mangan, M.T.; Waythomas, C.F.; Miller, T.P.; Trusdell, F.A.

    2003-01-01

    The Emmons Lake Volcanic Center on the Alaska Peninsula of southwestern Alaska is the site of at least two rhyolitic caldera-forming eruptions (C1 and C2) of late Quaternary age that are possibly the largest of the numerous caldera-forming eruptions known in the Aleutian arc. The deposits produced by these eruptions are widespread (eruptive volumes of >50 km3 each), and their association with Quaternary glacial and eolian deposits on the Alaska Peninsula and elsewhere in Alaska and northwestern Canada enhances the likelihood of establishing geochronological control on Quaternary stratigraphic records in this region. The pyroclastic deposits associated with the second caldera-forming eruption (C2) consist of loose, granular, airfall and pumice-flow deposits that extend for tens of kilometres beyond Emmons Lake caldera, reaching both the Bering Sea and Pacific Ocean coastlines north and south of the caldera. Geochronological and compositional data on C2 deposits indicate a correlation with the Dawson tephra, a 24 000 14C BP (27 000 calibrated years BP), widespread bed of silicic ash found in loess deposits in west-central Yukon Territory, Canada. The correlation clearly establishes the Dawson tephra as the time-stratigraphic marker of the last glacial maximum.

  11. Mapping the North Sea base-Quaternary: using 3D seismic to fill a gap in the geological record

    NASA Astrophysics Data System (ADS)

    Lamb, Rachel; Huuse, Mads; Stewart, Margaret; Brocklehurst, Simon H.

    2014-05-01

    The identification and mapping of the base-Quaternary boundary in the central parts of the North Sea is problematic due to the change from an unconformable transition between Pliocene and Pleistocene deltaic deposits in the southern North Sea to a conformable one further north (Sejrup et al 1991; Gatliff et al 1994). The best estimates of the transition use seismic reflection data to identify a 'crenulated reflector' (Buckley 2012), or rely on correlating sparse biostratigraphy (Cameron et al 1987). Recent integration of biostratigraphy, pollen analysis, paleomagnetism and amino acid analysis in the Dutch and Danish sectors (Rasmussen et al 2005; Kuhlmann et al 2006) allows greater confidence in the correlation to a regional 3D seismic dataset and show that the base-Quaternary can be mapped across the entire basin. The base-Quaternary has been mapped using the PGS MegaSurvey dataset from wells in the Danish Sector along the initially unconformable horizon and down the delta front into the more conformable basin giving a high degree of confidence in the horizon pick. The mapped horizon is presented here alongside the difference between this new interpretation and the previously interpreted base-Quaternary (Buckley 2012). The revised base-Quaternary surface reaches a depth of 1248 ms TWT or approximately 1120 m (assuming average velocity of 1800 m/s) showing an elongate basin shape that follows the underlying structure of the Central Graben. The difference between the revised base-Quaternary and the traditional base-Quaternary reaches a maximum of over 600 ms TWT or approximately 540 m in the south-west with over 300 ms TWT or approximately 270 m at the Josephine well (56° 36.11'N, 2° 27.09'E) in the centre of the basin. Mapping this new base-Quaternary allows for the interpretation of the paleo-envionrment during the earliest Quaternary. Seismic attribute analysis indicates a deep water basin with sediment deposition from multiple deltas and redistribution by deep

  12. Forming Stereogenic Centers in Acyclic Systems from Alkynes.

    PubMed

    Vabre, Roxane; Island, Biana; Diehl, Claudia J; Schreiner, Peter R; Marek, Ilan

    2015-08-17

    The combined carbometalation/zinc homologation followed by reactions with α-heterosubstituted aldehydes and imines proceed through a chair-like transition structure with the substituent of the incoming aldehyde residue preferentially occupying a pseudo-axial position to avoid the two gauche interactions. The heteroatom in the axial position produces a chelated intermediate (and not a Cornforth-Evans transition structure for α-chloro aldehydes and imines) leading to a face differentiation in the allylation reaction. This method provides access to functionalized products in which three new carbon-carbon bonds and two to three stereogenic centers, including a quaternary one, were created in acyclic systems in a single-pot operation from simple alkynes. PMID:26130570

  13. Forming Stereogenic Centers in Acyclic Systems from Alkynes.

    PubMed

    Vabre, Roxane; Island, Biana; Diehl, Claudia J; Schreiner, Peter R; Marek, Ilan

    2015-08-17

    The combined carbometalation/zinc homologation followed by reactions with α-heterosubstituted aldehydes and imines proceed through a chair-like transition structure with the substituent of the incoming aldehyde residue preferentially occupying a pseudo-axial position to avoid the two gauche interactions. The heteroatom in the axial position produces a chelated intermediate (and not a Cornforth-Evans transition structure for α-chloro aldehydes and imines) leading to a face differentiation in the allylation reaction. This method provides access to functionalized products in which three new carbon-carbon bonds and two to three stereogenic centers, including a quaternary one, were created in acyclic systems in a single-pot operation from simple alkynes.

  14. 2007 Rocky Mountain Section Friends of the Pleistocene Field Trip - Quaternary Geology of the San Luis Basin of Colorado and New Mexico, September 7-9, 2007

    USGS Publications Warehouse

    Machette, Michael N.; Coates, Mary-Margaret; Johnson, Margo L.

    2007-01-01

    Prologue Welcome to the 2007 Rocky Mountain Cell Friends of the Pleistocene Field Trip, which will concentrate on the Quaternary geology of the San Luis Basin of Colorado and New Mexico. To our best knowledge, Friends of the Pleistocene (FOP) has never run a trip through the San Luis Basin, although former trips in the region reviewed the 'Northern Rio Grande rift' in 1987 and the 'Landscape History and Processes on the Pajarito Plateau' in 1996. After nearly a decade, the FOP has returned to the Rio Grande rift, but to an area that has rarely hosted a trip with a Quaternary focus. The objective of FOP trips is to review - in the field - new and exciting research on Quaternary geoscience, typically research being conducted by graduate students. In our case, the research is more topically oriented around three areas of the San Luis Basin, and it is being conducted by a wide range of Federal, State, academic, and consulting geologists. This year's trip is ambitious?we will spend our first day mainly on the Holocene record around Great Sand Dunes National Park and Preserve, the second day on the Quaternary stratigraphy around the San Luis Hills, including evidence for Lake Alamosa and the 1.0 Ma Mesita volcano, and wrap up the trip's third day in the Costilla Plain and Sunshine Valley reviewing alluvial stratigraphy, the history of the Rio Grande, and evidence for young movement on the Sangre de Cristo fault zone. In the tradition of FOP trips, we will be camping along the field trip route for this meeting. On the night before our trip, we will be at the Great Sand Dunes National Park and Preserve's Pinyon Flats Campground, a group facility located about 2 miles north of the Visitors Center. After the first day's trip, we will dine and camp in the Bachus pit, about 3 miles southwest of Alamosa. For the final night (after day 2), we will bed down at La Junta Campground at the Bureau of Land Management (BLM) Wild and Scenic Rivers State Recreation Area, west of Questa

  15. Ruthenium-catalyzed C-C coupling of fluorinated alcohols with allenes: dehydrogenation at the energetic limit of β-hydride elimination.

    PubMed

    Sam, Brannon; Luong, Tom; Krische, Michael J

    2015-04-27

    Ruthenium(II) complexes catalyze the CC coupling of 1,1-disubstituted allenes and fluorinated alcohols to form homoallylic alcohols bearing all-carbon quaternary centers with good to complete levels of diastereoselectivity. Whereas fluorinated alcohols are relatively abundant and tractable, the corresponding aldehydes are often not commercially available because of their instability.

  16. A Tin(IV) Chloride Promoted Tandem C-O Bond Cleavage/Nazarov Cyclization/Nucleophilic Addition Reaction of 1,1-Disubstituted Allylic Ethers toward the Synthesis of Multisubstituted Indenes.

    PubMed

    Yang, Chao; Xu, Zheng-Liang; Shao, Hui; Mou, Xue-Qing; Wang, Jie; Wang, Shao-Hua

    2015-11-01

    A novel SnCl4-promoted tandem reaction toward multisubstituted indenes via a sequential C-O bond cleavage/Nazarov cyclization/nucleophilic addition reaction has been developed to afford a series of multisubstituted indenes with an all-carbon quaternary center in moderate to good yields. PMID:26465205

  17. Emergency Operations Center at Johnson Space Center

    NASA Technical Reports Server (NTRS)

    Caylor, Gary C.

    1997-01-01

    In June 1966, at the start of the Gulf Coast hurricane season, the Johnson Space Center (JSC) celebrated the opening of its new 4,000-square foot, state-of-the-art Emergency Operations Center (EOC). The new EOC has been upgraded and enhanced to support a wide spectrum of emergencies affecting JSC and neighboring communities. One of the main features of the EOC is its premier computerized dispatch center. The new system unites many of JSC's critical emergency functions into one integrated network. It automatically monitors fire alarms, security entrances, and external cameras. It contains the JSC inventory of hazardous materials, by building and room, and can call up Material Safety Data Sheets for most of the generic hazardous materials used on-site. The EOC is available for community use during area emergencies such as hurricanes and is a welcome addition to the Clear Lake/Galveston Bay Area communities' emergency response resources.

  18. Refining estimates of Quaternary slip on the Karakoram Fault System, Ladakh, NW India

    NASA Astrophysics Data System (ADS)

    Bohon, W.; Arrowsmith, R.; Hodges, K. V.; Heimsath, A. M.

    2013-12-01

    The NW-SE striking, dextral Karakoram fault system (KFS) stretches for more than 1200 km from the Pamirs of Central Asia at least as far southeast as the Kailas area of Tibet. It is one of the major tectonic features in the Himalayan orogen, yet considerable controversy remains about the time-integrated slip rate of the system. Geodetic data suggest present-day motion along the entire KFS occurs at 1-3 mm/yr (Wright et al., 2004, Science 305; Jade et al., 2010, GSA 116), but estimates for the integrated late Quaternary slip along various segments of the system - based on the reconstruction of dated, offset geomorphic and geologic features - range from ca. 4 mm/yr to ca. 32 mm/yr (Liu et al., 1991 in Avouac and Tapponier, 1993, GRL 20; Brown et al., 2002, JGR 107; Chevalier et al., 2005, Science 307). In the Ladakh region of NW India (34°45.27'N, 77°33.57'E), the KFS expresses as northern ('Pangong') and southern ('Tangtse') strands bounding the Pangong Range. The lack of documented Quaternary offset along the southern fault strand has led most researchers to assume that Quaternary slip on the KFS in this region was partitioned exclusively to the northern fault strand (Searle, 1998, Geological Society [London] Special Publication 135; Phillips et al., 2004, EPSL 226; Rutter et al., 2007, Journal of Structural Geology 29). However, our more recent field work in the northwestern Pangong Range has documented significant Quaternary activity along the Tangtse fault strand. Along this strand in the Tangyar Valley (34°14.26'N, 77°55.05'E), an incised debris cone has erosional risers offset ~160 m right laterally and ~25 m vertically (east side up) which is consistent with the dextral-oblique transpressional sense of motion for the KFS in this region. 10Be concentration depth profiles yield a preliminary minimum exposure age of ~30,000 yrs for the offset debris fan surfaces, which provides a maximum slip rate of ~5 mm/yr. Adjacent to the debris cone is a lower and

  19. Slope Deposits and (Paleo)Soils as Geoarchives to Reconstruct Late Quaternary Environments of Southern Africa

    NASA Astrophysics Data System (ADS)

    Huerkamp, K.; Voelkel, J.; Heine, K.; Bens, O.

    2009-04-01

    Although it is clear that large, rapid temperature changes have occurred during the last glacial-interglacial cycle and the Holocene in southern Africa, we have only limited, and often imprecise, knowledge of how the major moisture-bearing atmospheric circulation systems have reacted to these changes. Using slope deposits and soils as palaeoclimatic geoarchives we will overcome these constraints. The role of many geoarchives in the reconstruction of the Quaternary climate in southern Africa remains controversial, since the paleoclimate data are based on evidence from marine cores, lake sediments, speleothems and spring sinter, fluvial sediments, aeolian sands and dust, colluvium, and coastal sediments. To elucidate climate controls on Quaternary landscape evolution and to use these data for palaeoclimatic reconstructions, thus far slope deposits and soils have been investigated. Climatic controls on these cycles are incompletely known. The availability of results from earlier fieldwork, micromorphology, Optical Stimulated Luminescence (OSL), 14C dating and stable carbon isotope analysis will permit a thorough assessment of slope deposits and soils in terms of their palaeoenvironmental potential. The knowledge of suitable areas and sites in different climatic zones of southern Africa where slope deposits and soils have already been found document the late Quaternary climatic history and even climatic anomalies (e.g. Younger Dryas period at Eksteenfontein, 8.2 ka event at Tsumkwe, 4 ka event in the Auob valley, Little Ice Age in the Namib Desert). The findings will show the late Quaternary history of precipitation fluctuations, of the shifting of the ITCZ (and the ABF - Agulhas-Benguela Front), of wind intensities and directions, and of extreme precipitation events. The project will employ state-of-the-art geoscience methodology to interpret the record of precipitation changes of the late Quaternary, including the shifting of the summer and winter rain belts, the

  20. Late Quaternary Faulting along the San Juan de los Planes Fault Zone, Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Busch, M. M.; Coyan, J. A.; Arrowsmith, J.; Maloney, S. J.; Gutierrez, G.; Umhoefer, P. J.

    2007-12-01

    As a result of continued distributed deformation in the Gulf Extensional Province along an oblique-divergent plate margin, active normal faulting is well manifest in southeastern Baja California. By characterizing normal-fault related deformation along the San Juan de los Planes fault zone (SJPFZ) southwest of La Paz, Baja California Sur we contribute to understanding the patterns and rates of faulting along the southwest gulf-margin fault system. The geometry, history, and rate of faulting provide constraints on the relative significance of gulf-margin deformation as compared to axial system deformation. The SJPFZ is a major north-trending structure in the southern Baja margin along which we focused our field efforts. These investigations included: a detailed strip map of the active fault zone, including delineation of active scarp traces and geomorphic surfaces on the hanging wall and footwall; fault scarp profiles; analysis of bedrock structures to better understand how the pattern and rate of strain varied during the development of this fault zone; and a gravity survey across the San Juan de los Planes basin to determine basin geometry and fault behavior. The map covers a N-S swath from the Gulf of California in the north to San Antonio in the south, an area ~45km long and ~1-4km wide. Bedrock along the SJPFZ varies from Cretaceous Las Cruces Granite in the north to Cretaceous Buena Mujer Tonalite in the south and is scarred by shear zones and brittle faults. The active scarp-forming fault juxtaposes bedrock in the footwall against Late Quaternary sandstone-conglomerate. This ~20m wide zone is highly fractured bedrock infused with carbonate. The northern ~12km of the SJPFZ, trending 200°, preserves discontinuous scarps 1-2km long and 1-3m high in Quaternary units. The scarps are separated by stretches of bedrock embayed by hundreds of meters-wide tongues of Quaternary sandstone-conglomerate, implying low Quaternary slip rate. Further south, ~2 km north of the