Sample records for allocation barrier concept

  1. Homogeneous v. Heterogeneous: Is Tracking a Barrier to Equity?

    ERIC Educational Resources Information Center

    Polansky, Harvey B.

    1995-01-01

    Tracking has contributed considerably to the basic inequality of funding among American schools. To move to a heterogenous environment, districts must understand the concept of resource and program equity, commit to a planning process that allocates time and resources, provide ongoing inservice, downplay standardized test results, and phase-in…

  2. Perceived barriers, benefits, and motives for physical activity: two primary-care physical activity prescription programs.

    PubMed

    Patel, Asmita; Schofield, Grant M; Kolt, Gregory S; Keogh J, W L

    2013-01-01

    This study examined whether perceived barriers, benefits, and motives for physical activity differed based on allocation to 2 different types of primary-care activity-prescription programs (pedometer-based vs. time-based Green Prescription). Eighty participants from the Healthy Steps study completed a questionnaire that assessed their perceived barriers, benefits, and motives for physical activity. Factor analysis was carried out to identify common themes of barriers, benefits, and motives for physical activity. Factor scores were then used to explore between-groups differences for perceived barriers, benefits, and motives based on group allocation and demographic variables. No significant differences were found in factor scores based on allocation. Demographic variables relating to the existence of chronic health conditions, weight status, and older age were found to significantly influence perceived barriers, benefits, and motives for physical activity. Findings suggest that the addition of a pedometer to the standard Green Prescription does not appear to increase perceived motives or benefits or decrease perceived barriers for physical activity in low-active older adults.

  3. How to Do Random Allocation (Randomization)

    PubMed Central

    Shin, Wonshik

    2014-01-01

    Purpose To explain the concept and procedure of random allocation as used in a randomized controlled study. Methods We explain the general concept of random allocation and demonstrate how to perform the procedure easily and how to report it in a paper. PMID:24605197

  4. Rethinking Reinforcement: Allocation, Induction, and Contingency

    ERIC Educational Resources Information Center

    Baum, William M.

    2012-01-01

    The concept of reinforcement is at least incomplete and almost certainly incorrect. An alternative way of organizing our understanding of behavior may be built around three concepts: "allocation," "induction," and "correlation." Allocation is the measure of behavior and captures the centrality of choice: All behavior entails choice and consists of…

  5. Space Network Control Conference on Resource Allocation Concepts and Approaches

    NASA Technical Reports Server (NTRS)

    Moe, Karen L. (Editor)

    1991-01-01

    The results are presented of the Space Network Control (SNC) Conference. In the late 1990s, when the Advanced Tracking and Data Relay Satellite System is operational, Space Network communication services will be supported and controlled by the SNC. The goals of the conference were to survey existing resource allocation concepts and approaches, to identify solutions applicable to the Space Network, and to identify avenues of study in support of the SNC development. The conference was divided into three sessions: (1) Concepts for Space Network Allocation; (2) SNC and User Payload Operations Control Center (POCC) Human-Computer Interface Concepts; and (3) Resource Allocation Tools, Technology, and Algorithms. Key recommendations addressed approaches to achieving higher levels of automation in the scheduling process.

  6. A critical assessment on kidney allocation systems.

    PubMed

    Formica, Richard N

    2017-01-01

    The kidney allocation system that took effect on December 4, 2014 represents a significant improvement over the prior approach. It seeks to improve outcomes by longevity matching - pairing kidneys expected to function the longest with recipients expected to live the longest. It addresses the biological barriers faced by highly sensitized patients in an evidence based fashion and it begins to introduce the concept of medical need into kidney allocation by crediting time from the starting dialysis to a patient's waiting time. Additionally, it adds a more granular and continuous approach to classifying deceased donor kidneys through the kidney donor profile index and moves away from the dichotomous and flawed, standard criteria/extended criteria approach to allocating kidneys. Despite these changes, access to kidney transplantation across the age spectrum has remained intact and equitable. However even with these numerous positive improvements the system is not without its flaws. The increased sharing and by extension shipping of kidneys have created logistical challenges for organ procurement organizations and transplant centers. Early results seem to indicate that there have been an increase in cold ischemic time, an increase in delayed graft function and an increase in organ discard rate. There is also a reduced offer rate for children and while not a statistically significant decline in the number of transplants, it is a trend that requires close monitoring. Finally, the new kidney allocation system has done nothing to address the glaring deficiencies in the multi-organ allocation practices, all of which include a kidney, in the United States. Therefore despite the improvements made in kidney allocation, there is work yet to be done to ensure that the allocation of life saving and life prolonging organs for transplantation is done in a fashion consistent with ethical principles, based on science and free from local self interest so that this national resource is used for the betterment of the population it is meant to serve. Copyright © 2016. Published by Elsevier Inc.

  7. Examination of Resource Allocation in Education: Connecting Spending to Student Performance. Research Report.

    ERIC Educational Resources Information Center

    Pan, Diane; Rudo, Zena H.; Schneider, Cynthia L.; Smith-Hansen, Lotte

    This document reports on a study on the relationship between resources and student performance. The study examined district-level patterns of resource allocation, district and school resource practices implemented to improve student performance, and barriers and challenges to efficient resource allocation faced by districts and schools. The study…

  8. Compound Event Barrier Coverage in Wireless Sensor Networks under Multi-Constraint Conditions.

    PubMed

    Zhuang, Yaoming; Wu, Chengdong; Zhang, Yunzhou; Jia, Zixi

    2016-12-24

    It is important to monitor compound event by barrier coverage issues in wireless sensor networks (WSNs). Compound event barrier coverage (CEBC) is a novel coverage problem. Unlike traditional ones, the data of compound event barrier coverage comes from different types of sensors. It will be subject to multiple constraints under complex conditions in real-world applications. The main objective of this paper is to design an efficient algorithm for complex conditions that can combine the compound event confidence. Moreover, a multiplier method based on an active-set strategy (ASMP) is proposed to optimize the multiple constraints in compound event barrier coverage. The algorithm can calculate the coverage ratio efficiently and allocate the sensor resources reasonably in compound event barrier coverage. The proposed algorithm can simplify complex problems to reduce the computational load of the network and improve the network efficiency. The simulation results demonstrate that the proposed algorithm is more effective and efficient than existing methods, especially in the allocation of sensor resources.

  9. Compound Event Barrier Coverage in Wireless Sensor Networks under Multi-Constraint Conditions

    PubMed Central

    Zhuang, Yaoming; Wu, Chengdong; Zhang, Yunzhou; Jia, Zixi

    2016-01-01

    It is important to monitor compound event by barrier coverage issues in wireless sensor networks (WSNs). Compound event barrier coverage (CEBC) is a novel coverage problem. Unlike traditional ones, the data of compound event barrier coverage comes from different types of sensors. It will be subject to multiple constraints under complex conditions in real-world applications. The main objective of this paper is to design an efficient algorithm for complex conditions that can combine the compound event confidence. Moreover, a multiplier method based on an active-set strategy (ASMP) is proposed to optimize the multiple constraints in compound event barrier coverage. The algorithm can calculate the coverage ratio efficiently and allocate the sensor resources reasonably in compound event barrier coverage. The proposed algorithm can simplify complex problems to reduce the computational load of the network and improve the network efficiency. The simulation results demonstrate that the proposed algorithm is more effective and efficient than existing methods, especially in the allocation of sensor resources. PMID:28029118

  10. Development of a Technical Basis and Guidance for Advanced SMR Function Allocation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jacques Hugo; David Gertman; Jeffrey Joe

    This report presents the results from three key activities for FY13 that influence the definition of new concepts of operations for advanced Small Modular Reactors (AdvSMR: a) the development of a framework for the analysis of the functional environmental, and structural attributes, b) the effect that new technologies and operational concepts would have on the way functions are allocated to humans or machines or combinations of the two, and c) the relationship between new concepts of operations, new function allocations, and human performance requirements.

  11. Appraisal of Space Words and Allocation of Emotion Words in Bodily Space

    PubMed Central

    Marmolejo-Ramos, Fernando; Elosúa, María Rosa; Yamada, Yuki; Hamm, Nicholas Francis; Noguchi, Kimihiro

    2013-01-01

    The body-specificity hypothesis (BSH) predicts that right-handers and left-handers allocate positive and negative concepts differently on the horizontal plane, i.e., while left-handers allocate negative concepts on the right-hand side of their bodily space, right-handers allocate such concepts to the left-hand side. Similar research shows that people, in general, tend to allocate positive and negative concepts in upper and lower areas, respectively, in relation to the vertical plane. Further research shows a higher salience of the vertical plane over the horizontal plane in the performance of sensorimotor tasks. The aim of the paper is to examine whether there should be a dominance of the vertical plane over the horizontal plane, not only at a sensorimotor level but also at a conceptual level. In Experiment 1, various participants from diverse linguistic backgrounds were asked to rate the words “up”, “down”, “left”, and “right”. In Experiment 2, right-handed participants from two linguistic backgrounds were asked to allocate emotion words into a square grid divided into four boxes of equal areas. Results suggest that the vertical plane is more salient than the horizontal plane regarding the allocation of emotion words and positively-valenced words were placed in upper locations whereas negatively-valenced words were placed in lower locations. Together, the results lend support to the BSH while also suggesting a higher saliency of the vertical plane over the horizontal plane in the allocation of valenced words. PMID:24349112

  12. Application of an ecological framework to examine barriers to the adoption of safer conception strategies by HIV-affected couples.

    PubMed

    Saleem, Haneefa T; Surkan, Pamela J; Kerrigan, Deanna; Kennedy, Caitlin E

    2016-01-01

    Safer conception interventions can significantly reduce the risk of horizontal HIV transmission between HIV-serodiscordant partners. However, prior to implementing safer conception interventions, it is essential to understand potential barriers to their adoption so that strategies can be developed to overcome these barriers. This paper examines potential barriers to the adoption of safer conception strategies by HIV-affected couples in Iringa, Tanzania using an ecological framework. We interviewed 30 HIV-positive women, 30 HIV-positive men and 30 health providers engaged in delivering HIV-related services. We also conducted direct observations at five health facilities. Findings suggest that there are multiple barriers to safer conception that operate at the individual, relational, environmental, structural, and super-structural levels. The barriers to safer conception identified are complex and interact across these levels. Barriers at the individual level included antiretroviral adherence, knowledge of HIV status, knowledge and acceptability of safer conception strategies, and poor nutrition. At the relational level, unplanned pregnancies, non-disclosure of status, gendered power dynamics within relationships, and patient-provider interactions posed a threat to safer conception. HIV stigma and distance to health facilities were environmental barriers to safer conception. At the structural level there were multiple barriers to safer conception, including limited safer conception policy guidelines for people living with HIV (PLHIV), lack of health provider training in safer conception strategies and preconception counseling for PLHIV, limited resources, and lack of integration of HIV and sexual and reproductive health services. Poverty and gender norms were super-structural factors that influenced and reinforced barriers to safer conception, which influenced and operated across different levels of the framework. Multi-level interventions are needed to ensure adoption of safer conception strategies and reduce the risk of HIV transmission between partners within HIV-serodiscordant couples.

  13. Zinc allocation and re-allocation in rice.

    PubMed

    Stomph, Tjeerd Jan; Jiang, Wen; Van Der Putten, Peter E L; Struik, Paul C

    2014-01-01

    Agronomy and breeding actively search for options to enhance cereal grain Zn density. Quantifying internal (re-)allocation of Zn as affected by soil and crop management or genotype is crucial. We present experiments supporting the development of a conceptual model of whole plant Zn allocation and re-allocation in rice. Two solution culture experiments using (70)Zn applications at different times during crop development and an experiment on within-grain distribution of Zn are reported. In addition, results from two earlier published experiments are re-analyzed and re-interpreted. A budget analysis showed that plant zinc accumulation during grain filling was larger than zinc allocation to the grains. Isotope data showed that zinc taken up during grain filling was only partly transported directly to the grains and partly allocated to the leaves. Zinc taken up during grain filling and allocated to the leaves replaced zinc re-allocated from leaves to grains. Within the grains, no major transport barrier was observed between vascular tissue and endosperm. At low tissue Zn concentrations, rice plants maintained concentrations of about 20 mg Zn kg(-1) dry matter in leaf blades and reproductive tissues, but let Zn concentrations in stems, sheath, and roots drop below this level. When plant zinc concentrations increased, Zn levels in leaf blades and reproductive tissues only showed a moderate increase while Zn levels in stems, roots, and sheaths increased much more and in that order. In rice, the major barrier to enhanced zinc allocation towards grains is between stem and reproductive tissues. Enhancing root to shoot transfer will not contribute proportionally to grain zinc enhancement.

  14. Zinc allocation and re-allocation in rice

    PubMed Central

    Stomph, Tjeerd Jan; Jiang, Wen; Van Der Putten, Peter E. L.; Struik, Paul C.

    2014-01-01

    Aims: Agronomy and breeding actively search for options to enhance cereal grain Zn density. Quantifying internal (re-)allocation of Zn as affected by soil and crop management or genotype is crucial. We present experiments supporting the development of a conceptual model of whole plant Zn allocation and re-allocation in rice. Methods: Two solution culture experiments using 70Zn applications at different times during crop development and an experiment on within-grain distribution of Zn are reported. In addition, results from two earlier published experiments are re-analyzed and re-interpreted. Results: A budget analysis showed that plant zinc accumulation during grain filling was larger than zinc allocation to the grains. Isotope data showed that zinc taken up during grain filling was only partly transported directly to the grains and partly allocated to the leaves. Zinc taken up during grain filling and allocated to the leaves replaced zinc re-allocated from leaves to grains. Within the grains, no major transport barrier was observed between vascular tissue and endosperm. At low tissue Zn concentrations, rice plants maintained concentrations of about 20 mg Zn kg−1 dry matter in leaf blades and reproductive tissues, but let Zn concentrations in stems, sheath, and roots drop below this level. When plant zinc concentrations increased, Zn levels in leaf blades and reproductive tissues only showed a moderate increase while Zn levels in stems, roots, and sheaths increased much more and in that order. Conclusions: In rice, the major barrier to enhanced zinc allocation towards grains is between stem and reproductive tissues. Enhancing root to shoot transfer will not contribute proportionally to grain zinc enhancement. PMID:24478788

  15. The fundamental closed-form solution of control-related states of kth order S3PR system with left-side non-sharing resource places of Petri nets

    NASA Astrophysics Data System (ADS)

    Chao, Daniel Yuh; Yu, Tsung Hsien

    2016-01-01

    Due to the state explosion problem, it has been unimaginable to enumerate reachable states for Petri nets. Chao broke the barrier earlier by developing the very first closed-form solution of the number of reachable and other states for marked graphs and the kth order system. Instead of using first-met bad marking, we propose 'the moment to launch resource allocation' (MLR) as a partial deadlock avoidance policy for a large, real-time dynamic resource allocation system. Presently, we can use the future deadlock ratio of the current state as the indicator of MLR due to which the ratio can be obtained real-time by a closed-form formula. This paper progresses the application of an MLR concept one step further on Gen-Left kth order systems (one non-sharing resource place in any position of the left-side process), which is also the most fundamental asymmetric net structure, by the construction of the system's closed-form solution of the control-related states (reachable, forbidden, live and deadlock states) with a formula depending on the parameters of k and the location of the non-sharing resource. Here, we kick off a new era of real-time, dynamic resource allocation decisions by constructing a generalisation formula of kth order systems (Gen-Left) with r* on the left side but at arbitrary locations.

  16. Design and Evaluation of Nextgen Aircraft Separation Assurance Concepts

    NASA Technical Reports Server (NTRS)

    Johnson, Walter; Ho, Nhut; Arutyunov, Vladimir; Laue, John-Luke; Wilmoth, Ian

    2012-01-01

    To support the development and evaluation of future function allocation concepts for separation assurance systems for the Next Generation Air Transportation System, this paper presents the design and human-in-the-loop evaluation of three feasible function allocation concepts that allocate primary aircraft separation assurance responsibilities and workload to: 1) pilots; 2) air traffic controllers (ATC); and 3) automation. The design of these concepts also included rules of the road, separation assurance burdens for aircraft of different equipage levels, and utilization of advanced weather displays paired with advanced conflict detection and resolution automation. Results of the human-in-the-loop simulation show that: a) all the concepts are robust with respect to weather perturbation; b) concept 1 (pilots) had highest throughput, closest to assigned spacing, and fewest violations of speed and altitude restrictions; c) the energy of the aircraft during the descent phase was better managed in concepts 1 and 2 (pilots and ATC) than in concept 3 (automation), in which the situation awareness of pilots and controllers was lowest, and workload of pilots was highest. The paper also discusses further development of these concepts and their augmentation and integration with future air traffic management tools and systems that are being considered for NextGen.

  17. Evaluation of a patient navigation program.

    PubMed

    Koh, Catherine; Nelson, Joan M; Cook, Paul F

    2011-02-01

    This study examined the value and effectiveness of a patient navigation program in terms of timeliness of access to cancer care, resolution of barriers, and satisfaction in 55 patients over a six-month period. Although not statistically significant, the time interval between diagnostic biopsy to first consultation with a cancer specialist after program implementation was reduced from an average of 14.6 days to 12.8 days. The time interval between diagnostic biopsy to initiation of cancer treatment also was reduced from 30 days to 26.2 days (not statistically significant). In addition, 71% of patient barriers were resolved by the time treatment was initiated. Overall, patients were highly satisfied with their navigated care experience. Consistent evaluation and monitoring of quality-of-care indicators are critical to further develop the program and to direct resource allocation. Oncology nurses participating in patient navigation programs should be encouraged to evaluate their importance and impact in this developing concept. Nurses should seek roles that allow them to optimize the effective use of their specialized knowledge and skills to the benefit of patients along the cancer care continuum.

  18. Visual selective attention with virtual barriers.

    PubMed

    Schneider, Darryl W

    2017-07-01

    Previous studies have shown that interference effects in the flanker task are reduced when physical barriers (e.g., hands) are placed around rather than below a target flanked by distractors. One explanation of this finding is the referential coding hypothesis, whereby the barriers serve as reference objects for allocating attention. In five experiments, the generality of the referential coding hypothesis was tested by investigating whether interference effects are modulated by the placement of virtual barriers (e.g., parentheses). Modulation of flanker interference was found only when target and distractors differed in size and the virtual barriers were beveled wood-grain objects. Under these conditions and those of previous studies, the author conjectures that an impression of depth was produced when the barriers were around the target, such that the target was perceived to be on a different depth plane than the distractors. Perception of depth in the stimulus display might have led to referential coding of the stimuli in three-dimensional (3-D) space, influencing the allocation of attention beyond the horizontal and vertical dimensions. This 3-D referential coding hypothesis is consistent with research on selective attention in 3-D space that shows flanker interference is reduced when target and distractors are separated in depth.

  19. Investigation of novel acoustic barrier concepts phase I: concept development and preliminary evaluation

    DOT National Transportation Integrated Search

    2003-06-01

    In a previous research project [SQDH 2002-3; "Study of the Performance of Acoustic Barriers for Indiana Toll Roads,"] the influence of : environmental factors and of advanced sound barrier concepts was investigated. The presence of temperature gradie...

  20. Distributed Optimal Consensus Over Resource Allocation Network and Its Application to Dynamical Economic Dispatch.

    PubMed

    Li, Chaojie; Yu, Xinghuo; Huang, Tingwen; He, Xing; Chaojie Li; Xinghuo Yu; Tingwen Huang; Xing He; Li, Chaojie; Huang, Tingwen; He, Xing; Yu, Xinghuo

    2018-06-01

    The resource allocation problem is studied and reformulated by a distributed interior point method via a -logarithmic barrier. By the facilitation of the graph Laplacian, a fully distributed continuous-time multiagent system is developed for solving the problem. Specifically, to avoid high singularity of the -logarithmic barrier at boundary, an adaptive parameter switching strategy is introduced into this dynamical multiagent system. The convergence rate of the distributed algorithm is obtained. Moreover, a novel distributed primal-dual dynamical multiagent system is designed in a smart grid scenario to seek the saddle point of dynamical economic dispatch, which coincides with the optimal solution. The dual decomposition technique is applied to transform the optimization problem into easily solvable resource allocation subproblems with local inequality constraints. The good performance of the new dynamical systems is, respectively, verified by a numerical example and the IEEE six-bus test system-based simulations.

  1. Age Differences in the Effects of Conceptual Integration Training on Resource Allocation in Sentence Processing

    PubMed Central

    Stine-Morrow, Elizabeth A. L.; Noh, Soo Rim; Shake, Matthew C.

    2009-01-01

    This research examined age differences in the accommodation of reading strategies as a consequence of explicit instruction in conceptual integration. In Experiment 1, young, middle-aged, and older adults read sentences for delayed recall using a moving window method. Readers in an experimental group received instruction in making conceptual links during reading while readers in a control group were simply encouraged to allocate effort. Regression analysis to decompose word-by-word reading times in each condition isolated the time allocated to conceptual processing at the point in the text at which new concepts were introduced, as well as at clause and sentence boundaries. While younger adults responded to instructions by differentially allocating effort to sentence wrap-up, older adults allocated effort to intrasentence wrap-up and on new concepts as they were introduced, suggesting that older readers optimized their allocation of effort to linguistic computations for textbase construction within their processing capacity. Experiment 2 verified that conceptual integration training improved immediate recall among older readers as a consequence of engendering allocation to conceptual processing. PMID:19941199

  2. Cost Accounting for Decision Makers.

    ERIC Educational Resources Information Center

    Kaneklides, Ann L.

    1985-01-01

    Underscores the importance of informed decision making through accurate anticipation of cost incurrence in light of changing economic and environmental conditions. Explains the concepts of cost accounting, full allocation of costs, the selection of an allocation base, the allocation of indirect costs, depreciation, and implications for community…

  3. 75 FR 14596 - Family Violence Prevention and Services/Grants for Domestic Violence Shelters/Grants to Native...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-26

    ..., isolation from family and friends, harm to children living with a parent or caretaker who is either... communities compound the basic dynamics of family violence. Barriers such as the isolation of vast rural areas.... The formula has two parts, the Tribal population base allocation and a population category allocation...

  4. Are Indirect Benefits Relevant to Health Care Allocation Decisions?

    PubMed Central

    Du Toit, Jessica; Millum, Joseph

    2016-01-01

    Abstract When allocating scarce healthcare resources, the expected benefits of alternative allocations matter. But, there are different kinds of benefits. Some are direct benefits to the recipient of the resource such as the health improvements of receiving treatment. Others are indirect benefits to third parties such as the economic gains from having a healthier workforce. This article considers whether only the direct benefits of alternative healthcare resource allocations are relevant to allocation decisions, or whether indirect benefits are relevant too. First, we distinguish different conceptions of direct and indirect benefits and argue that only a recipient conception could be morally relevant. We analyze four arguments for thinking that indirect benefits should not count and argue that none is successful in showing that the indirectness of a benefit is a good reason not to count it. We conclude that direct and indirect benefits should be evaluated in the same way. PMID:27465773

  5. Spot the difference: Operational event sequence diagrams as a formal method for work allocation in the development of single-pilot operations for commercial aircraft.

    PubMed

    Harris, Don; Stanton, Neville A; Starr, Alison

    2015-01-01

    Function Allocation methods are important for the appropriate allocation of tasks between humans and automated systems. It is proposed that Operational Event Sequence Diagrams (OESDs) provide a simple yet rigorous basis upon which allocation of work can be assessed. This is illustrated with respect to a design concept for a passenger aircraft flown by just a single pilot where the objective is to replace or supplement functions normally undertaken by the second pilot with advanced automation. A scenario-based analysis (take off) was used in which there would normally be considerable demands and interactions with the second pilot. The OESD analyses indicate those tasks that would be suitable for allocation to automated assistance on the flight deck and those tasks that are now redundant in this new configuration (something that other formal Function Allocation approaches cannot identify). Furthermore, OESDs are demonstrated to be an easy to apply and flexible approach to the allocation of function in prospective systems. OESDs provide a simple yet rigorous basis upon which allocation of work can be assessed. The technique can deal with the flexible, dynamic allocation of work and the deletion of functions no longer required. This is illustrated using a novel design concept for a single-crew commercial aircraft.

  6. Children’s Recognition of Fairness and Others’ Welfare in a Resource Allocation Task: Age Related Changes

    PubMed Central

    Rizzo, Michael T.; Elenbaas, Laura; Cooley, Shelby; Killen, Melanie

    2016-01-01

    The present study investigated age-related changes regarding children’s (N = 136) conceptions of fairness and others’ welfare in a merit-based resource allocation paradigm. To test whether children at 3- to 5-years-old and 6- to 8-years-old took others’ welfare into account when dividing resources, in addition to merit and equality concerns, children were asked to allocate, judge, and reason about allocations of necessary (needed to avoid harm) and luxury (enjoyable to have) resources to a hardworking and a lazy character. While 3- to 5-year-olds did not differentiate between distributing luxury and necessary resources, 6- to 8-year-olds allocated luxury resources more meritoriously than necessary resources. Further, children based their allocations of necessary resources on concerns for others’ welfare, rather than merit, even when one character was described as working harder. The findings revealed that, with age, children incorporated the concerns for others’ welfare and merit into their conceptions of fairness in a resource allocation context, and prioritized these concerns differently depending on whether they were allocating luxury or necessary resources. Further, with age, children weighed multiple moral concerns including equality, merit, and others’ welfare, when determining the fair allocation of resources. PMID:27455189

  7. Conceptions of Justice in the Examination Systems of England, Germany, and Sweden: A Look at Safeguards of Fair Procedure and Possibilities of Appeal

    ERIC Educational Resources Information Center

    Waldow, Florian

    2014-01-01

    In societies following a meritocratic ideal, educational certificates and examinations play a key role in allocating life chances to individuals. Procedures for allocating life chances need to be perceived as fair by those concerned if examinations and certificates are to possess legitimacy. This article traces and compares basic conceptions of…

  8. Exploring Trends and Barriers to Implementation of Branding and Marketing Concepts in the School Nutrition Setting

    ERIC Educational Resources Information Center

    Castillo, Alexandra; Nettles, Mary Frances

    2012-01-01

    Purpose/Objectives: The purpose of this research study was to identify perceptions, practices, advantages, and barriers to implementation of branding concepts in school nutrition (SN) programs. Methods: Seven SN directors participated in an expert panel session to discuss trends and barriers to implementation of branding concepts in SN programs.…

  9. Scarcity, Conflict, and Equity in Allocating Public Recreation Resources.

    ERIC Educational Resources Information Center

    Shelby, Bo; Danley, Mark

    The conflict between the interests of commercial outfitters and private boaters in the use of whitewater rivers is examined. A discussion is presented on the literature on scarcity, allocation, and conflict among groups. These concepts are applied to the allocation of public resources on whitewater rivers. The conflicting interest groups are…

  10. Cost Allocation of Multiagency Water Resource Projects: Game Theoretic Approaches and Case Study

    NASA Astrophysics Data System (ADS)

    Lejano, Raul P.; Davos, Climis A.

    1995-05-01

    Water resource projects are often jointly carried out by a number of communities and agencies. Participation in a joint project depends on how costs are allocated among the participants and how cost shares compare with the cost of independent projects. Cooperative N-person game theory offers approaches which yield cost allocations that satisfy rationality conditions favoring participation. A new solution concept, the normalized nucleolus, is discussed and applied to a water reuse project in southern California. Results obtained with the normalized nucleolus are compared with those derived with more traditional solution concepts, namely, the nucleolus and the Shapley value.

  11. In-vehicle signing concepts: An analytical precursor to an in-vehicle information system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Spelt, P.F.; Tufano, D.R.; Knee, H.E.

    The purpose of the project described in this report is to develop alternative In-Vehicle Signing (IVS) system concepts based on allocation of the functions associated with driving a road vehicle. In the driving milieu, tasks can be assigned to one of three agents, the driver, the vehicle or the infrastructure. Assignment of tasks is based on a philosophy of function allocation which can emphasize any of several philosophical approaches. In this project, function allocations were made according to the current practice in vehicle design and signage as well as a human-centered strategy. Several IVS system concepts are presented based onmore » differing functional allocation outcomes. A design space for IVS systems is described, and a technical analysis of a map-based and sever beacon-based IVS systems are presented. Because of problems associated with both map-based and beacon-based concepts, a hybrid IVS concept was proposed. The hybrid system uses on-board map-based databases to serve those areas in which signage can be anticipated to be relatively static, such as large metropolitan areas where few if any new roads will be built. For areas where sign density is low, and/or where population growth causes changes in traffic flow, beacon-based concepts function best. For this situation, changes need only occur in the central database from which sign information is transmitted. This report presents system concepts which enable progress from the IVS system concept-independent functional requirements to a more specific set of system concepts which facilitate analysis and selection of hardware and software to perform the functions of IVS. As such, this phase of the project represents a major step toward the design and development of a prototype WS system. Once such a system is developed, a program of testing, evaluation, an revision will be undertaken. Ultimately, such a system can become part of the road vehicle of the future.« less

  12. A system dynamics model of a large R&D program

    NASA Astrophysics Data System (ADS)

    Ahn, Namsung

    Organizations with large R&D activities must deal with a hierarchy of decision regarding resource allocation. At the highest level of allocation, the decision is related to the total allocation to R&D as some portion of revenue. The middle level of allocation deals with the allocation among phases of the R&D process. The lowest level of decisions relates to the resource allocation to specific projects within a specific phase. This study focuses on developing an R&D model to deal with the middle level of allocation, i.e., the allocation among phases of research such as basic research, development, and demonstration. The methodology used to develop the R&D model is System Dynamics. Our modeling concept is innovative in representing each phase of R&D as consisting of two parts: projects under way, and an inventory of successful but not-yet- exploited projects. In a simple world, this concept can yield an exact analytical solution for allocation of resources among phases. But in a real world, the concept should be improved by adding more complex structures with nonlinear behaviors. Two particular nonlinear feedbacks are incorporated into the R&D model. The probability of success for any specific project is assumed partly dependent upon resources allocated to the project. Further, the time required to reach a conclusion regarding the success or failure of a project is also assumed dependent upon the level of resources allocated. In addition, the number of successful projects partly depends on the inventory of potential ideas in the previous stage that can be exploited. This model can provide R&D management with insights into the effect of changing allocations to phases whether those changes are internally or externally driven. With this model, it is possible to study the effectiveness of management decisions in a continuous fashion. Managers can predict payoffs for a host of different policies. In addition, as new research results accumulate, a re- assessment of program goals can be implemented easily and allocations adjusted to enhance continuously the likelihood of success, and to optimize payoffs. Finally, this model can give managers a quantitative rationale for program evaluation and permit the quantitative assessment of various externally imposed changes. (Copies available exclusively from MIT Libraries, Rm. 14-0551, Cambridge, MA 02139-4307. Ph. 617-253-5668; Fax 617-253-1690.)

  13. Analysis and Research on the Optimal Allocation of Regional Water Resources

    NASA Astrophysics Data System (ADS)

    rui-chao, Xi; yu-jie, Gu

    2018-06-01

    Starting from the basic concept of optimal allocation of water resources, taking the allocation of water resources in Tianjin as an example, the present situation of water resources in Tianjin is analyzed, and the multi-objective optimal allocation model of water resources is used to optimize the allocation of water resources. We use LINGO to solve the model, get the optimal allocation plan that meets the economic and social benefits, and put forward relevant policies and regulations, so as to provide theoretical which is basis for alleviating and solving the problem of water shortage.

  14. Are Indirect Benefits Relevant to Health Care Allocation Decisions?

    PubMed

    Du Toit, Jessica; Millum, Joseph

    2016-10-01

    When allocating scarce healthcare resources, the expected benefits of alternative allocations matter. But, there are different kinds of benefits. Some are direct benefits to the recipient of the resource such as the health improvements of receiving treatment. Others are indirect benefits to third parties such as the economic gains from having a healthier workforce. This article considers whether only the direct benefits of alternative healthcare resource allocations are relevant to allocation decisions, or whether indirect benefits are relevant too. First, we distinguish different conceptions of direct and indirect benefits and argue that only a recipient conception could be morally relevant. We analyze four arguments for thinking that indirect benefits should not count and argue that none is successful in showing that the indirectness of a benefit is a good reason not to count it. We conclude that direct and indirect benefits should be evaluated in the same way. Published by Oxford University Press on behalf of the Journal of Medicine and Philosophy, Inc. 2016.

  15. The allocation of valenced concepts onto 3D space.

    PubMed

    Marmolejo-Ramos, Fernando; Tirado, Carlos; Arshamian, Edward; Vélez, Jorge Iván; Arshamian, Artin

    2018-06-01

    The valence-space metaphor research area investigates the metaphorical mapping of valenced concepts onto space. Research findings from this area indicate that positive, neutral, and negative concepts are associated with upward, midward, and downward locations, respectively, in the vertical plane. The same research area has also indicated that such concepts seem to have no preferential location on the horizontal plane. The approach-avoidance effect consists in decreasing the distance between positive stimuli and the body (i.e. approach) and increasing the distance between negative stimuli and the body (i.e. avoid). Thus, the valence-space metaphor accounts for the mapping of valenced concepts onto the vertical and horizontal planes, and the approach-avoidance effect accounts for the mapping of valenced concepts onto the "depth" plane. By using a cube conceived for the study of allocation of valenced concepts onto 3D space, we show in three studies that positive concepts are placed in upward locations and near the participants' body, negative concepts are placed in downward locations and far from the participants' body, and neutral concepts are placed in between these concepts in both planes.

  16. Dietary Bacillus subtilis-based direct-fed microbials alleviate LPS-induced intestinal immunological stress and improve intestinal barrier gene expression in commercial broiler chickens

    USDA-ARS?s Scientific Manuscript database

    The present study investigated the effects of B. subtilis-based probiotics on performance, modulation of host inflammatory responses and intestinal barrier integrity of broilers subjected to LPS challenge. Birds at day 0 of age were randomly allocated to one of the 3 dietary treatments - controls, ...

  17. Methods for Allocating Highway Costs

    DOT National Transportation Integrated Search

    1981-04-01

    Microeconomic theory and other concepts related to pricing are reviewed and applied to the problem of designing highway user charges. In view of the emphasis in the Congressional request for the Highway Cost Allocation Study on setting charges in acc...

  18. NASA's UAS NAS Access Project

    NASA Technical Reports Server (NTRS)

    Johnson, Charles W.

    2011-01-01

    The vision of the Unmanned Aircraft System (UAS) Integration in the National Airspace System (NAS) Project is "A global transportation system which allows routine access for all classes of UAS." The goal of the UAS Integration in the NAS Project is to "contribute capabilities that reduce technical barriers related to the safety and operational challenges associated with enabling routine UAS access to the NAS." This goal will be accomplished through a two-phased approach based on development of system-level integration of key concepts, technologies and/or procedures, and demonstrations of integrated capabilities in an operationally relevant environment. Phase 1 will take place the first two years of the Project and Phase 2 will take place the following three years. The Phase 1 and 2 technical objectives are: Phase 1: Developing a gap analysis between current state of the art and the Next Generation Air Transportation System (NextGen) UAS Concept of Operations . Validating the key technical areas identified by this Project . Conducting initial modeling, simulation, and flight testing activities . Completing Sub-project Phase 1 deliverables (spectrum requirements, comparative analysis of certification methodologies, etc.) and continue Phase 2 preparation (infrastructure, tools, etc.) Phase 2: Providing regulators with a methodology for developing airworthiness requirements for UAS, and data to support development of certifications standards and regulatory guidance . Providing systems-level, integrated testing of concepts and/or capabilities that address barriers to routine access to the NAS. Through simulation and flight testing, address issues including separation assurance, communications requirements, and human systems integration in operationally relevant environments. The UAS in the NAS Project will demonstrate solutions in specific technology areas, which will address operational/safety issues related to UAS access to the NAS. Since the resource allocation for this Project is limited ($150M over the five years), the focus is on reducing the technical barriers where NASA has unique capabilities. As a result, technical areas, such as Sense and Avoid (SAA) and beyond line of sight command and control will not be addressed. While these are critical barriers to UAS access, currently, there is a great deal of global effort being exercised to address these challenge areas. Instead, specific technology development in areas where there is certainty that NASA can advance the research to high technology readiness levels will be the Project's focus. Specific sub-projects include Separation Assurance, Human Systems Integration, Communications, Certification, and Integrated Test and Evaluation. Each sub-project will transfer technologies to relevant key stakeholders and decision makers through research transition teams, technology forums, or through other analogous means.

  19. Overcoming Barriers to Implementation of Evidence-Based Practice Concepts in Athletic Training Education: Perceptions of Select Educators

    PubMed Central

    Manspeaker, Sarah; Van Lunen, Bonnie

    2011-01-01

    Context: The need to include evidence-based practice (EBP) concepts in entry-level athletic training education is evident as the profession transitions toward using evidence to inform clinical decision making. Objective: To evaluate athletic training educators' experience with implementation of EBP concepts in Commission on Accreditation of Athletic Training Education (CAATE)-accredited entry-level athletic training education programs in reference to educational barriers and strategies for overcoming these barriers. Design: Qualitative interviews of emergent design with grounded theory. Setting: Undergraduate CAATE-accredited athletic training education programs. Patients or Other Participants: Eleven educators (3 men, 8 women). The average number of years teaching was 14.73 ± 7.06. Data Collection and Analysis: Interviews were conducted to evaluate perceived barriers and strategies for overcoming these barriers to implementation of evidence-based concepts in the curriculum. Interviews were explored qualitatively through open and axial coding. Established themes and categories were triangulated and member checked to determine trustworthiness. Results: Educators identified 3 categories of need for EBP instruction: respect for the athletic training profession, use of EBP as part of the decision-making toolbox, and third-party reimbursement. Barriers to incorporating EBP concepts included time, role strain, knowledge, and the gap between clinical and educational practices. Suggested strategies for surmounting barriers included identifying a starting point for inclusion and approaching inclusion from a faculty perspective. Conclusions: Educators must transition toward instruction of EBP, regardless of barriers present in their academic programs, in order to maintain progress with other health professions' clinical practices and educational standards. Because today's students are tomorrow's clinicians, we need to include EBP concepts in entry-level education to promote critical thinking, inspire potential research interest, and further develop the available body of knowledge in our growing clinical practice. PMID:22488139

  20. Overcoming barriers to implementation of evidence-based practice concepts in athletic training education: perceptions of select educators.

    PubMed

    Manspeaker, Sarah; Van Lunen, Bonnie

    2011-01-01

    The need to include evidence-based practice (EBP) concepts in entry-level athletic training education is evident as the profession transitions toward using evidence to inform clinical decision making. To evaluate athletic training educators' experience with implementation of EBP concepts in Commission on Accreditation of Athletic Training Education (CAATE)-accredited entry-level athletic training education programs in reference to educational barriers and strategies for overcoming these barriers. Qualitative interviews of emergent design with grounded theory. Undergraduate CAATE-accredited athletic training education programs. Eleven educators (3 men, 8 women). The average number of years teaching was 14.73 ± 7.06. Interviews were conducted to evaluate perceived barriers and strategies for overcoming these barriers to implementation of evidence-based concepts in the curriculum. Interviews were explored qualitatively through open and axial coding. Established themes and categories were triangulated and member checked to determine trustworthiness. Educators identified 3 categories of need for EBP instruction: respect for the athletic training profession, use of EBP as part of the decision-making toolbox, and third-party reimbursement. Barriers to incorporating EBP concepts included time, role strain, knowledge, and the gap between clinical and educational practices. Suggested strategies for surmounting barriers included identifying a starting point for inclusion and approaching inclusion from a faculty perspective. Educators must transition toward instruction of EBP, regardless of barriers present in their academic programs, in order to maintain progress with other health professions' clinical practices and educational standards. Because today's students are tomorrow's clinicians, we need to include EBP concepts in entry-level education to promote critical thinking, inspire potential research interest, and further develop the available body of knowledge in our growing clinical practice.

  1. An Updated Equilibrium Machine

    NASA Astrophysics Data System (ADS)

    Schultz, Emeric

    2008-08-01

    A device that can demonstrate equilibrium, kinetic, and thermodynamic concepts is described. The device consists of a leaf blower attached to a plastic container divided into two chambers by a barrier of variable size and form. Styrofoam balls can be exchanged across the barrier when the leaf blower is turned on and various air pressures are applied. Equilibrium can be approached from different distributions of balls in the container under different conditions. The Le Châtelier principle can be demonstrated. Kinetic concepts can be demonstrated by changing the nature of the barrier, either changing the height or by having various sized holes in the barrier. Thermodynamic concepts can be demonstrated by taping over some or all of the openings and restricting air flow into container on either side of the barrier.

  2. Overcoming Terminology Barrier Using Web Resources for Cross-Language Medical Information Retrieval

    PubMed Central

    Lu, Wen-Hsiang; Lin, Ray Shih-Jui; Chan, Yi-Che; Chen, Kuan-Hsi

    2006-01-01

    A number of authoritative medical websites, such as PubMed and MedlinePlus, provide consumers with the most up-to-date health information. However, non-English speakers often encounter not only language barriers (from other languages to English) but also terminology barriers (from laypersons’ terms to professional medical terms) when retrieving information from these websites. Our previous work addresses language barriers by developing a multilingual medical thesaurus, Chinese-English MeSH, while this study presents an approach to overcome terminology barriers based on Web resources. Two techniques were utilized in our approach: monolingual concept mapping using approximate string matching and crosslingual concept mapping using Web resources. The evaluation shows that our approach can significantly improve the performance on MeSH concept mapping and cross-language medical information retrieval. PMID:17238395

  3. Implementing Cardiopulmonary Resuscitation Training Programs in High Schools: Iowa's Experience.

    PubMed

    Hoyme, Derek B; Atkins, Dianne L

    2017-02-01

    To understand perceived barriers to providing cardiopulmonary resuscitation (CPR) education, implementation processes, and practices in high schools. Iowa has required CPR as a graduation requirement since 2011 as an unfunded mandate. A cross-sectional study was performed through multiple choice surveys sent to Iowa high schools to collect data about school demographics, details of CPR programs, cost, logistics, and barriers to implementation, as well as automated external defibrillator training and availability. Eighty-four schools responded (26%), with the most frequently reported school size of 100-500 students and faculty size of 25-50. When the law took effect, 51% of schools had training programs already in place; at the time of the study, 96% had successfully implemented CPR training. Perceived barriers to implementation were staffing, time commitment, equipment availability, and cost. The average estimated startup cost was <$1000 US, and the yearly maintenance cost was <$500 with funds typically allocated from existing school resources. The facilitator was a school official or volunteer for 81% of schools. Average estimated training time commitment per student was <2 hours. Automated external defibrillators are available in 98% of schools, and 61% include automated external defibrillator training in their curriculum. Despite perceived barriers, school CPR training programs can be implemented with reasonable resource and time allocations. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Implementing Cardiopulmonary Resuscitation Training Programs in High Schools: Iowa's Experience

    PubMed Central

    Hoyme, Derek B.; Atkins, Dianne L.

    2017-01-01

    Objective To understand perceived barriers to providing cardiopulmonary resuscitation (CPR) education, implementation processes, and practices in high schools. Study design Iowa has required CPR as a graduation requirement since 2011 as an unfunded mandate. A cross-sectional study was performed through multiple choice surveys sent to Iowa high schools to collect data about school demographics, details of CPR programs, cost, logistics, and barriers to implementation, as well as automated external defibrillator training and availability. Results Eighty-four schools responded (26%), with the most frequently reported school size of 100-500 students and faculty size of 25-50. When the law took effect, 51% of schools had training programs already in place; at the time of the study, 96% had successfully implemented CPR training. Perceived barriers to implementation were staffing, time commitment, equipment availability, and cost. The average estimated startup cost was <$1000 US, and the yearly maintenance cost was <$500 with funds typically allocated from existing school resources. The facilitator was a school official or volunteer for 81% of schools. Average estimated training time commitment per student was <2 hours. Automated external defibrillators are available in 98% of schools, and 61% include automated external defibrillator training in their curriculum. Conclusions Despite perceived barriers, school CPR training programs can be implemented with reasonable resource and time allocations. PMID:27852456

  5. Higher-Education Budgeting at the State Level: Concepts and Principles.

    ERIC Educational Resources Information Center

    Jones, Dennis P.

    New approaches to allocating state resources to colleges are discussed. Budgeting and resource allocation principles are considered that: (1) reflect the unique context of higher education; (2) are consistent with sound budgeting and management principles; and (3) represent institutional mechanisms applied at the state level rather than approaches…

  6. The Frozen Price Game

    ERIC Educational Resources Information Center

    Alden, Lori

    2003-01-01

    In this article, the author discusses the educational frozen price game she developed to teach the basic economic principle of price allocation. In addition to demonstrating the advantages of price allocation, the game also illustrates such concepts as opportunity costs, cost benefit comparisons, and the trade-off between efficiency and equity.…

  7. Enhancing the Quality of Financial Advice with Web 2.0 - An Approach Considering Social Capital in the Private Asset Allocation

    NASA Astrophysics Data System (ADS)

    Kundisch, Dennis; Zorzi, Robin

    Although theoretically necessary, social capital is not considered within the process of asset allocation for private investors. Both the lack of appropriate practical valuation concepts and the effort of providing and processing the required information as input for a valuation were obstacles to include social capital in this process. However, first theoretical financial models for the evaluation of social capital recently have become available. Moreover, the fast growth of business community websites and the technological progress in Web 2.0 tools that allow and acquire the active involvement of users, facilitate the provision and processing of valuation relevant information. In this paper we focus on the second aspect and propose a social software-based concept that allows for an integration of social capital in the asset allocation process.

  8. Mechanism of supporting sub-communicator collectives with o(64) counters as opposed to one counter for each sub-communicator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blocksome, Michael; Kumar, Sameer; Mamidala, Amith R.

    A system and method for enhancing barrier collective synchronization on a computer system comprises a computer system including a data storage device. The computer system includes a program stored in the data storage device and steps of the program being executed by a processor. The system includes providing a plurality of communicators for storing state information for a barrier algorithm. Each communicator designates a master core in a multi-processor environment of the computer system. The system allocates or designates one counter for each of a plurality of threads. The system configures a table with a number of entries equal tomore » the maximum number of threads. The system sets a table entry with an ID associated with a communicator when a process thread initiates a collective. The system determines an allocated or designated counter by searching entries in the table.« less

  9. Why Can't I Play Here? The Classroom: A World in Miniature. Instructional Activities Series.

    ERIC Educational Resources Information Center

    Witthuhn, Burton O.

    Third in the elementary set of teacher-developed instructional activities for teaching geography, this activity investigates spatial allocation through discussion and observation of classroom arrangements. Classroom space allocated for the teacher's desk, aisles, study area, and trash cans illustrates real-world locational concepts of geography…

  10. Contextual and interdependent causes of climate change adaptation barriers for water management: responses from regional and local institutions in Himachal Pradesh, India

    NASA Astrophysics Data System (ADS)

    Azhoni, Adani; Holman, Ian; Jude, Simon

    2016-04-01

    Research on adaptation barriers is gaining increasing prominence as the need for climate change adaptation becomes evident. This research seeks to identify and understand the reasons for key barriers preventing water institutions in the mountainous Himalayan state of Himachal Pradesh in northern India from adapting to climate change. Semi-structured interviews were carried out in January & February 2015 with representatives from twenty-seven key governmental, academic, NGO and commercial institutions in the State, with responsibilities spanning from municipal water supply to irrigation and hydropower generation in addition to environmental conservation. Empirical analysis of the transcripts found that inadequate knowledge capacity, poor implementation of policies, inadequate resources, normative work culture, weak governance, unavailability and inaccessibility of data & information and limited inter-institutional networks are key barriers for adaptation. Although these generic barriers are similar to those reported elsewhere in literature, they are identified as having locally-contextual root causes. For example, the inadequate resources are identified to be occurring as a consequence of the fragmentation of resources allocation among others. This is due to competing developmental priorities and the desire of the political leadership to please the maximum number of electors rather than the more-usual inadequate budgetary allocation and climate scepticism. The identified individual barriers are found to be highly inter-dependent and closely intertwined which enables the identification of leverage points of interventions that can maximise removal of barriers. For example, breaking down key barriers for data and information accessibility will have to involve normative attitudinal change, through sensitisation of the larger picture of the role of accurate and accessible data; changes in working style involving moving from paper-based data management to digital; and institutional and structural changes through legislation or formal inter-institutional agreements for increasing data accessibility and sharing. This presentation will demonstrate how adaptation barriers in Himachal Pradesh are contextually interconnected by a range of cultural, systemic, geographical and political underlying causes and how this understanding can be used to increase the adaptive capacity of this climatically sensitive region.

  11. Effects of a Skin Barrier Cream on Management of Incontinence-Associated Dermatitis in Older Women: A Cluster Randomized Controlled Trial.

    PubMed

    Kon, Yuka; Ichikawa-Shigeta, Yoshie; Iuchi, Terumi; Nakajima, Yukari; Nakagami, Gojiro; Tabata, Keiko; Sanada, Hiromi; Sugama, Junko

    The purpose of this study was to examine the effects of a skin barrier cream with moisturization and skin-protectant characteristics for improving the severity of incontinence-associated dermatitis (IAD) pertaining to the skin physiology and appearance. We measured the following outcomes: (1) skin physiological characteristics indicating skin protection and enhancement of the skin's moisture barrier (stratum corneum hydration, dermis hydration level, transepidermal water loss, and skin pH); and (2) changes in skin appearance (the degree of erythema and pigmentation, and the sulcus cutis condition). Single-blind, cluster randomized controlled trial. The study was conducted in a long-term care facility in Japan between November 7, 2011, and May 6, 2012. We used block randomization to obtain a random sample of 6 (4 experimental and 2 control) out of 10 available wards. All subjects were elderly women with IAD of the buttock or inner thigh. We assessed 295 patients, but only 33 met inclusion criteria; 18 were allocated to the experimental group and 15 were allocated to the control group. All participants were managed with cleansing with a skin cleanser and application of a moisturizer daily. In addition, a skin barrier cream designed to enhance the skin's moisture barrier and act as a protective barrier was applied to the skin of patients in the experimental group 3 times a day when absorptive briefs were changed. Skin physiological and appearance characteristics were scored only at the buttock or thigh area. All data were collected on days 1 and 14 of the study. Univariate analysis found that the erythema index was lower in the intervention group than in the control group at day 14 (P = .004). Multivariate analysis found significant associations between use of the skin barrier cream and increased stratum corneum hydration (β= .443, P = .031), decreased skin pH (β=-.439, P = .020), and magnitude of erythema (β=-.451, P = .018). Study findings suggest that a barrier cream designed to enhance the skin's moisture barrier and act as a skin protectant increased stratum corneum hydration, reduced cutaneous pH, and reduced erythema.

  12. Barriers to Optimal Palliative Care of Lung Transplant Candidates

    PubMed Central

    Colman, Rebecca E.; Curtis, J. Randall; Nelson, Judith E.; Efferen, Linda; Hadjiliadis, Denis; Levine, Deborah J.; Meyer, Keith C.; Padilla, Maria; Strek, Mary; Varkey, Basil

    2013-01-01

    Background: The provision of effective palliative care is of great importance to patients awaiting lung transplantation. Although the prospect of lung transplantation provides hope to patients and their families, these patients are usually very symptomatic from their underlying disease. Methods: An e-mail questionnaire was sent to members of the American College of Chest Physicians’ Transplant NetWork and the Pulmonary Council of the International Society for Heart and Lung Transplantation (ISHLT). The survey included questions about barriers to providing palliative care, the availability of palliative care services, and recommended strategies to improve palliative care for lung transplant candidates. Results: The 158 respondents represented approximately 65% of transplant programs in the ISHLT registry. Respondents were in practice a mean of 11.3 (± 9) years, 70% were pulmonologists, 17% were surgeons, and 13% were other care providers. Barriers were classified into domains including patient factors, family factors, physician factors, and institutional/transplant program/lung allocation system factors. Significant patient/family barriers included unrealistic patient/family expectations about survival, unwillingness to plan end-of-life care, concerns about abandonment or inappropriate care after enrollment in a palliative care program, and family disagreements about care goals. For institutional/program/allocation system barriers, only the requirement for weight loss or gain to meet program-specific BMI requirements was identified. Significant physician barriers included competing time demands and the seemingly contradictory goals of transplant vs palliative care. Strategies recommended to improve palliative care included routine advance care planning for patients awaiting transplantation, access to palliative care specialists, training of transplant physicians in symptom management, and regular meetings among transplant physicians, nurses, patients, and families. Conclusions: Physicians providing care to lung transplant candidates reported considerable barriers to the delivery and acceptance of palliative care and identified specific strategies to improve palliative care for lung transplant candidates. PMID:22922517

  13. Randomized Trial of a Web-Based Intervention to Address Barriers to Clinical Trials.

    PubMed

    Meropol, Neal J; Wong, Yu-Ning; Albrecht, Terrance; Manne, Sharon; Miller, Suzanne M; Flamm, Anne Lederman; Benson, Al Bowen; Buzaglo, Joanne; Collins, Michael; Egleston, Brian; Fleisher, Linda; Katz, Michael; Kinzy, Tyler G; Liu, Tasnuva M; Margevicius, Seunghee; Miller, Dawn M; Poole, David; Roach, Nancy; Ross, Eric; Schluchter, Mark D

    2016-02-10

    Lack of knowledge and negative attitudes have been identified as barriers to participation in clinical trials by patients with cancer. We developed Preparatory Education About Clinical Trials (PRE-ACT), a theory-guided, Web-based, interactive computer program, to deliver tailored video educational content to patients in an effort to overcome barriers to considering clinical trials as a treatment option. A prospective, randomized clinical trial compared PRE-ACT with a control condition that provided general clinical trials information produced by the National Cancer Institute (NCI) in text format. One thousand two hundred fifty-five patients with cancer were randomly allocated before their initial visit with an oncologist to PRE-ACT (n = 623) or control (n = 632). PRE-ACT had three main components: assessment of clinical trials knowledge and attitudinal barriers, values assessment with clarification back to patients, and provision of a video library tailored to address each patient's barriers. Outcomes included knowledge and attitudes and preparation for decision making about clinical trials. Both PRE-ACT and control interventions improved knowledge and attitudes (all P < .001) compared with baseline. Patients randomly allocated to PRE-ACT showed a significantly greater increase in knowledge (P < .001) and a significantly greater decrease in attitudinal barriers (P < .001) than did their control (text-only) counterparts. Participants in both arms significantly increased their preparedness to consider clinical trials (P < .001), and there was a trend favoring the PRE-ACT group (P < .09). PRE-ACT was also associated with greater patient satisfaction than was NCI text alone. These data show that patient education before the first oncologist visit improves knowledge, attitudes, and preparation for decision making about clinical trials. Both text and tailored video were effective. The PRE-ACT interactive video program was more effective than NCI text in improving knowledge and reducing attitudinal barriers. © 2015 by American Society of Clinical Oncology.

  14. Optimal allocation of invasive species surveillance with the maximum expected coverage concept

    Treesearch

    Denys Yemshanov; Robert G. Haight; Frank H. Koch; Bo Lu; Robert Venette; D. Barry Lyons; Taylor Scarr; Krista Ryall; Brian. Leung

    2015-01-01

    We address the problem of geographically allocating scarce survey resources to detect pests in their pathways of introduction given information about their likelihood of movement between origins and destinations. We introduce a model for selecting destination sites for survey that departs from the aim of reducing propagule pressure (PP) in pest destinations and instead...

  15. Analog Processor To Solve Optimization Problems

    NASA Technical Reports Server (NTRS)

    Duong, Tuan A.; Eberhardt, Silvio P.; Thakoor, Anil P.

    1993-01-01

    Proposed analog processor solves "traveling-salesman" problem, considered paradigm of global-optimization problems involving routing or allocation of resources. Includes electronic neural network and auxiliary circuitry based partly on concepts described in "Neural-Network Processor Would Allocate Resources" (NPO-17781) and "Neural Network Solves 'Traveling-Salesman' Problem" (NPO-17807). Processor based on highly parallel computing solves problem in significantly less time.

  16. A Framework for Optimal Control Allocation with Structural Load Constraints

    NASA Technical Reports Server (NTRS)

    Frost, Susan A.; Taylor, Brian R.; Jutte, Christine V.; Burken, John J.; Trinh, Khanh V.; Bodson, Marc

    2010-01-01

    Conventional aircraft generally employ mixing algorithms or lookup tables to determine control surface deflections needed to achieve moments commanded by the flight control system. Control allocation is the problem of converting desired moments into control effector commands. Next generation aircraft may have many multipurpose, redundant control surfaces, adding considerable complexity to the control allocation problem. These issues can be addressed with optimal control allocation. Most optimal control allocation algorithms have control surface position and rate constraints. However, these constraints are insufficient to ensure that the aircraft's structural load limits will not be exceeded by commanded surface deflections. In this paper, a framework is proposed to enable a flight control system with optimal control allocation to incorporate real-time structural load feedback and structural load constraints. A proof of concept simulation that demonstrates the framework in a simulation of a generic transport aircraft is presented.

  17. Comparison of Ground-Based and Airborne Function Allocation Concepts for NextGen Using Human-In-The-Loop Simulations

    NASA Technical Reports Server (NTRS)

    Wing, David J.; Prevot, Thomas; Murdoch, Jennifer L.; Cabrall, Christopher D.; Homola, Jeffrey R.; Martin, Lynne H.; Mercer, Joey S.; Hoadley, Sherwood T.; Wilson, Sara R.; Hubbs, Clay E.; hide

    2010-01-01

    Investigation of function allocation for the Next Generation Air Transportation System is being conducted by the National Aeronautics and Space Administration (NASA). To provide insight on comparability of different function allocations for separation assurance, two human-in-the-loop simulation experiments were conducted on homogeneous airborne and ground-based approaches to four-dimensional trajectory-based operations, one referred to as ground-based automated separation assurance (groundbased) and the other as airborne trajectory management with self-separation (airborne). In the coordinated simulations at NASA s Ames and Langley Research Centers, controllers for the ground-based concept at Ames and pilots for the airborne concept at Langley managed the same traffic scenarios using the two different concepts. The common scenarios represented a significant increase in airspace demand over current operations. Using common independent variables, the simulations varied traffic density, scheduling constraints, and the timing of trajectory change events. Common metrics were collected to enable a comparison of relevant results. Where comparisons were possible, no substantial differences in performance or operator acceptability were observed. Mean schedule conformance and flight path deviation were considered adequate for both approaches. Conflict detection warning times and resolution times were mostly adequate, but certain conflict situations were detected too late to be resolved in a timely manner. This led to some situations in which safety was compromised and/or workload was rated as being unacceptable in both experiments. Operators acknowledged these issues in their responses and ratings but gave generally positive assessments of the respective concept and operations they experienced. Future studies will evaluate technical improvements and procedural enhancements to achieve the required level of safety and acceptability and will investigate the integration of airborne and ground-based capabilities within the same airspace to leverage the benefits of each concept.

  18. A method to assess the allocation suitability of recreational activities: An economic approach

    NASA Astrophysics Data System (ADS)

    Wang, Hsiao-Lin

    1996-03-01

    Most existing methods of planning focus on development of a recreational area; less consideration is placed on the allocation of recreational activities within a recreational area. Most existing research emphasizes the economic benefits of developing a recreational area; few authors assessed the allocation suitability of recreational activities from an economic point of view. The purpose of this work was to develop a model to assess the allocation suitability of recreational activities according to the application of a concept of analysis of cost and benefit under a premise of ecological concern. The model was verified with a case study of Taiwan. We suggest that the proposed model should form a critical part of recreational planning.

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hao, He; Sun, Yannan; Carroll, Thomas E.

    We propose a coordination algorithm for cooperative power allocation among a collection of commercial buildings within a campus. We introduced thermal and power models of a typical commercial building Heating, Ventilation, and Air Conditioning (HVAC) system, and utilize model predictive control to characterize their power flexibility. The power allocation problem is formulated as a cooperative game using the Nash Bargaining Solution (NBS) concept, in which buildings collectively maximize the product of their utilities subject to their local flexibility constraints and a total power limit set by the campus coordinator. To solve the optimal allocation problem, a distributed protocol is designedmore » using dual decomposition of the Nash bargaining problem. Numerical simulations are performed to demonstrate the efficacy of our proposed allocation method« less

  20. Patch Network for Power Allocation and Distribution in Smart Materials

    NASA Technical Reports Server (NTRS)

    Golembiewski, Walter T.

    2000-01-01

    The power allocation and distribution (PAD) circuitry is capable of allocating and distributing a single or multiple sources of power over multi-elements of a power user grid system. The purpose of this invention is to allocate and distribute power that is collected by individual patch rectennas to a region of specific power-user devices, such as actuators. The patch rectenna converts microwave power into DC power. Then this DC power is used to drive actuator devices. However, the power from patch rectennas is not sufficient to drive actuators unless all the collected power is effectively used to drive another group by allocation and distribution. The power allocation and distribution (PAD) circuitry solves the shortfall of power for devices in a large array. The PAD concept is based on the networked power control in which power collected over the whole array of rectennas is allocated to a sub domain where a group of devices is required to be activated for operation. Then the allocated power is distributed to individual element of power-devices in the sub domain according to a selected run-mode.

  1. Physiological girdling of pine trees via phloem chilling: proof of concept

    Treesearch

    Kurt Johnsen; Chris Maier; Felipe Sanchez; Peter Anderson; John Butnor; Richard Waring; Sune Linder

    2007-01-01

    Quantifying below-ground carbon (C) allocation is particularly difficult as methods usually disturb the root– mycorrhizal–soil continuum. We reduced C allocation below ground of loblolly pine trees by: (1) physically girdling trees and (2) physiologically girdling pine trees by chilling the phloem. Chilling reduced cambium temperatures by approximately 18 °C. Both...

  2. Children's Recognition of Fairness and Others' Welfare in a Resource Allocation Task: Age Related Changes

    ERIC Educational Resources Information Center

    Rizzo, Michael T.; Elenbaas, Laura; Cooley, Shelby; Killen, Melanie

    2016-01-01

    The present study investigated age-related changes regarding children's (N = 136) conceptions of fairness and others' welfare in a merit-based resource allocation paradigm. To test whether children at 3- to 5-years-old and 6- to 8-years-old took others' welfare into account when dividing resources, in addition to merit and equality concerns,…

  3. The Credit Hour and Public Budgeting.

    ERIC Educational Resources Information Center

    Wellman, Jane V.

    2003-01-01

    Discusses the ways the credit hour has come to be used by public funding systems in higher education. The literature review shows that the credit hour has become a barrier to innovation and a way to create systemic inequities between institutions or sectors in resource allocation. (SLD)

  4. In-Vehicle Signing Concepts: An Analytical Precursor to an In-Vehicle Information System

    DOT National Transportation Integrated Search

    1996-01-01

    The purpose of the project described in this report is to develop alternative In-Vehicle Signing (IVS) system concepts based on allocation of the functions associated with driving a road vehicle. In the driving milieu, tasks can be assigned to one of...

  5. Outstanding Research Issues in Systematic Technology Prioritization for New Space Missions: Workshop Proceedings

    NASA Technical Reports Server (NTRS)

    Weisbin, C. R. (Editor)

    2004-01-01

    A workshop entitled, "Outstanding Research Issues in Systematic Technology Prioritization for New Space Missions," was convened on April 21-22, 2004 in San Diego, California to review the status of methods for objective resource allocation, to discuss the research barriers remaining, and to formulate recommendations for future development and application. The workshop explored the state-of-the-art in decision analysis in the context of being able to objectively allocate constrained technical resources to enable future space missions and optimize science return. This article summarizes the highlights of the meeting results.

  6. Demand and Financial Constraints in Eliminating Architectural and Technical Barriers for People with Disabilities in Poland

    PubMed Central

    Przybyła, Katarzyna

    2018-01-01

    The purpose of the study is to analyse the availability of financial resources for people with disabilities and to assess the needs satisfaction level of the disabled in order to eliminate architectural and technical barriers in Poland. The research conducted among the disabled affected by physical disability indicates that mobility barriers and obstacles remain among the most important problems encountered by people with disabilities. The research has shown that the problem of barriers increases with age. The elimination of architectural barriers requires, each time, higher financial expenditure, whereas the elimination of technical barriers improves the life quality of people with disabilities at low financial outlays. The average funding in Poland amounted to PLN 827.53 in 2016, including the funding of EUR 1453.60 for the elimination of architectural barriers and approx. EUR 582 for the removal of technical barriers. The financial resources allocated for this purpose do not cover the actual needs of the people with disabilities. The analysis revealed that the demand for investment in the elimination of barriers is increasing with age, whereas the expenditure of the Polish state is decreasing. PMID:29670742

  7. Portfolio Based Management

    ERIC Educational Resources Information Center

    Daigneau, William A.

    2010-01-01

    In this article, the author talks about Portfolio Management, a concept used to make allocation decisions in the world of financial investments. While much has been written about Portfolio theory, and the term is widely used in the facilities management industry, little is really understood about the concept and its real-world application. The…

  8. Child Day Care Recycling Fund Experiment.

    ERIC Educational Resources Information Center

    Bowen, Gary L.; Neenan, Peter A.

    This report describes the context, design, and findings of an evaluation of a welfare reform initiative, the Recycling Fund Concept, in Mecklenburg County, North Carolina. The proposed fund would allocate money to parents of preschool children who receive Aid to Families with Dependent Children (AFDC). The concept assumes that lack of child care…

  9. [A Reflection on the Policy of Transcultural Long-Term Care for the Indigenous Peoples in Taiwan].

    PubMed

    Subeq, Yi-Maun; Hsu, Mutsu

    2016-06-01

    Giving high-profile attention to socio-cultural and traditional beliefs in the promotion of long-term care policies enjoys strong, consensus support in the field of transcultural nursing. To protect the rights of indigenous people in Taiwan, the Ministry of Health and Welfare incorporated the concept of cultural care into the Long-term Care Services Act, which was approved by the Legislature in May 2014. However, the policies, resource strategies, manpower allocations, and staff educations and trainings related to this act are still await implementation in indigenous areas. Beyond the concept of professional healthcare, which considers cultural sensitivity, suitability, and ability, cultural care gives greater priority to crossing cultural barriers, integrating with the lifestyle of clients, and addressing their concerns in order to improve the well-being of target populations. The present article reviews current long-term care policy to highlight the importance of considering the cultural needs of the indigenous peoples of Taiwan in order to enhance the efficiency and impact of long-term care programs. Furthermore, the findings strongly recommend that additional resources be provided in order to meet the long-term care needs of indigenous communities. Finally, cultural-specific, long-term care service strategies should be promulgated in order to upgrade well-being in order to ease and comfort the feelings of indigenous people.

  10. Optimal allocation in annual plants and its implications for drought response

    NASA Astrophysics Data System (ADS)

    Caldararu, Silvia; Smith, Matthew; Purves, Drew

    2015-04-01

    The concept of plant optimality refers to the plastic behaviour of plants that results in lifetime and offspring fitness. Optimality concepts have been used in vegetation models for a variety of processes, including stomatal conductance, leaf phenology and biomass allocation. Including optimality in vegetation models has the advantages of creating process based models with a relatively low complexity in terms of parameter numbers but which are capable of reproducing complex plant behaviour. We present a general model of plant growth for annual plants based on the hypothesis that plants allocate biomass to aboveground and belowground vegetative organs in order to maintain an optimal C:N ratio. The model also represents reproductive growth through a second optimality criteria, which states that plants flower when they reach peak nitrogen uptake. We apply this model to wheat and maize crops at 15 locations corresponding to FLUXNET cropland sites. The model parameters are data constrained using a Bayesian fitting algorithm to eddy covariance data, satellite derived vegetation indices, specifically the MODIS fAPAR product and field level crop yield data. We use the model to simulate the plant drought response under the assumption of plant optimality and show that the plants maintain unstressed total biomass levels under drought for a reduction in precipitation of up to 40%. Beyond that level plant response stops being plastic and growth decreases sharply. This behaviour results simply from the optimal allocation criteria as the model includes no explicit drought sensitivity component. Models that use plant optimality concepts are a useful tool for simulation plant response to stress without the addition of artificial thresholds and parameters.

  11. Systematic planning of disconnection to enhance conservation success in a modified world.

    PubMed

    Hermoso, Virgilio; Januchowski-Hartley, Stephanie R; Linke, Simon

    2015-12-01

    Maintaining spatial-temporal connectivity for conservation is necessary to allow the persistence of ecological processes and the biodiversity they sustain. However, conservation practice in human-modified environments can also benefit from prescribed disconnection through the implementation of barriers. Barriers, such as fences or dams, and buffer zones can be a cost-effective way of addressing threats caused by a globally connected world, such as the propagation of invasive species and diseases, creating refuge areas for native biodiversity and helping reduce economic losses caused by native wildlife or invasive species. Despite the global attention that disconnection has received, no clear framework exists to guide the allocation of barriers for conservation management. Here we propose that the implementation of barriers for conservation should be systematically planned, considering ecological trade-offs for multiple species (easing threats vs. interruption of ecosystem processes) and socio-economic cost-benefits (implementation cost vs. reduced human-wildlife conflicts), rather than using ad-hoc opportunistic criteria or accommodating conservation needs for individual species. Such a systematic approach is necessary to ensure both socially acceptable and ecologically effective use of disconnections as a conservation tool and ideally planned across different realms so co-benefits or trade-offs can be accounted for. However, any implementation of disconnection for conservation should be cautiously considered if uncertainty in effectiveness of the barrier and ecological impacts to other species are high. We also suggest the need for improved approaches to monitoring to learn from previous successes and failures. Our recommendations should guide the systematic evaluation and allocation of barriers to help enhance the value of this conservation tool in the face of increasing propagation of threats worldwide. However, new tools and collaborative frameworks across different realms are needed to help stakeholders make better informed decision. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. PERMEABLE REACTIVE BARRIER TECHNOLOGIES FOR CONTAMINANT REMEDIATION

    EPA Science Inventory

    Environmental scientists are generally familiar with the concept of barriers for restricting the movement of contaminant plumes in ground water. Such barriers are typically constructed of highly impermeable emplacements of materials such as grouts, slurries, or sheet pilings to ...

  13. The Health Resources Allocation Model (HRAM) for the 21st century.

    PubMed

    Maire, Nicolas; Hegnauer, Michael; Nguyen, Dana; Godelmann, Lucas; Hoffmann, Axel; de Savigny, Don; Tanner, Marcel

    2012-05-01

    The Health Resources Allocation Model (HRAM) is an eLearning tool for health cadres and scientists introducing basic concepts of sub-national, rational district-based health planning and systems thinking under resources constraint. HRAM allows the evaluation of resource allocation strategies in relation to key outcome measures such as coverage, equity of services achieved and number of deaths and disability-adjusted life years (DALYs) prevented. In addition, the model takes into account geographical and demographic characteristics and populations' health seeking behaviour. It can be adapted to different socio-ecological and health system settings.

  14. Threshold concepts as barriers to understanding climate science

    NASA Astrophysics Data System (ADS)

    Walton, P.

    2013-12-01

    Whilst the scientific case for current climate change is compelling, the consequences of climate change have largely failed to permeate through to individuals. This lack of public awareness of the science and the potential impacts could be considered a key obstacle to action. The possible reasons for such limited success centre on the issue that climate change is a complex subject, and that a wide ranging academic, political and social research literature on the science and wider implications of climate change has failed to communicate the key issues in an accessible way. These failures to adequately communicate both the science and the social science of climate change at a number of levels results in ';communication gaps' that act as fundamental barriers to both understanding and engagement with the issue. Meyer and Land (2003) suggest that learners can find certain ideas and concepts within a discipline difficult to understand and these act as a barrier to deeper understanding of a subject. To move beyond these threshold concepts, they suggest that the expert needs to support the learner through a range of learning experiences that allows the development of learning strategies particular to the individual. Meyer and Land's research into these threshold concepts has been situated within Economics, but has been suggested to be more widely applicable though there has been no attempt to either define or evaluate threshold concepts to climate change science. By identifying whether common threshold concepts exist specifically in climate science for cohorts of either formal or informal learners, scientists will be better able to support the public in understanding these concepts by changing how the knowledge is communicated to help overcome these barriers to learning. This paper reports on the findings of a study that examined the role of threshold concepts as barriers to understanding climate science in a UK University and considers its implications for wider scientific engagement with the public to develop climate literacy. The analysis of 3 successive cohorts of students' journals who followed the same degree module identified that threshold concepts do exist within the field, such as those related to: role of ocean circulation, use of proxy indicators, forcing factors and feedback mechanisms. Once identified, the study looked at possible strategies to overcome these barriers to support student climate literacy. It concluded that the use of threshold concepts could be problematic when trying to improve climate literacy, as each individual has their own concepts they find ';troublesome' that do not necessarily relate to others. For scientists this presents the difficulty of how to develop a strategy that supports the individual that is cost and time effective. However, the study identifies that eLearning can be used effectively to help people understand troublesome knowledge.

  15. Alpha-Fair Resource Allocation under Incomplete Information and Presence of a Jammer

    NASA Astrophysics Data System (ADS)

    Altman, Eitan; Avrachenkov, Konstantin; Garnaev, Andrey

    In the present work we deal with the concept of alpha-fair resource allocation in the situation where the decision maker (in our case, the base station) does not have complete information about the environment. Namely, we develop a concept of α-fairness under uncertainty to allocate power resource in the presence of a jammer under two types of uncertainty: (a) the decision maker does not have complete knowledge about the parameters of the environment, but knows only their distribution, (b) the jammer can come into the environment with some probability bringing extra background noise. The goal of the decision maker is to maximize the α-fairness utility function with respect to the SNIR (signal to noise-plus-interference ratio). Here we consider a concept of the expected α-fairness utility function (short-term fairness) as well as fairness of expectation (long-term fairness). In the scenario with the unknown parameters of the environment the most adequate approach is a zero-sum game since it can also be viewed as a minimax problem for the decision maker playing against the nature where the decision maker has to apply the best allocation under the worst circumstances. In the scenario with the uncertainty about jamming being in the system the Nash equilibrium concept is employed since the agents have non-zero sum payoffs: the decision maker would like to maximize either the expected fairness or the fairness of expectation while the jammer would like to minimize the fairness if he comes in on the scene. For all the plots the equilibrium strategies in closed form are found. We have shown that for all the scenarios the equilibrium has to be constructed into two steps. In the first step the equilibrium jamming strategy has to be constructed based on a solution of the corresponding modification of the water-filling equation. In the second step the decision maker equilibrium strategy has to be constructed equalizing the induced by jammer background noise.

  16. Challenges of work-life balance for women physicians/mothers working in leadership positions.

    PubMed

    Schueller-Weidekamm, Claudia; Kautzky-Willer, Alexandra

    2012-08-01

    Female leadership in medicine is still disproportionately small, which might be due to the barriers of combining work and family. The aim of this study was, first, to perform a strengths, weakness, opportunities, and threats (SWOT) analysis and, second, to create a strategic concept for career development. In this study, all women in leadership positions in the health care system in Vienna, Austria, with at least 1 child (n = 8), were interviewed about the advantages and disadvantages of gender with regard to career development, the strengths and weaknesses of female leadership, and their work-life balance. Different factors that influenced the work-life balance were specified, and career strategies to realize adequate solutions were developed. The sporadic focus on career advancement, time-consuming child care, responsibility for family life, and a woman's tendency toward understatement were barriers to career development. Work-family enrichment has a positive spillover effect that spreads positive energy and helps to balance the work-life relationship. For each individual, the allocation and interaction of different resources such as time, money, scope of decision making, and physical, emotional, and social resources, were essential to maintain the individual work-life balance. In addition to the existing "glass ceiling," the predominant responsibility for child care is still borne by the woman. However, mentoring programs, coaching, networking, and support of the partner or of other people help to strengthen female "soft" skills and achieve a work-life balance. Copyright © 2012 Elsevier HS Journals, Inc. All rights reserved.

  17. Control of microbial contamination.

    NASA Technical Reports Server (NTRS)

    Mcdade, J. J.

    1971-01-01

    Two specific applications are discussed of microbial contamination control in planetary quarantine. Under the first concept, using the clean room to control environmental microorganisms, the objective is to reduce the microbial species and keep the numbers of microorganisms within an enclosure at a low level. The clean room concept is aimed at obtaining a product that has a controlled and reduced level of microbial contamination. Under the second concept, using the microbiological barrier to control microbial contamination of a specific product, the barrier techniques are designed to prevent the entry of any microorganisms into a sterile work area. Thus the assembly of space flight hardware within the confines of a microbiological barrier is aimed at obtaining a sterile product. In theory and practice, both approaches are shown to be applicable to the planetary quarantine program.

  18. Women deans' perceptions of the gender gap in American medical deanships.

    PubMed

    Humberstone, Elizabeth

    2017-01-01

    : Women account for 16% of deans of American medical schools. To investigate this gender gap, female deans were interviewed about the barriers facing women advancing toward deanships. The author conducted semi-structured interviews with eight women deans. Interviews were analyzed using provisional coding and sub coding techniques. Four main themes emerged during the interviews: (1) the role of relationships in personal and career development, (2) leadership challenges, (3) barriers between women and leadership advancement, and (4) recommendations for improvement. Recommendations included allocating resources, mentorship, career flexibility, faculty development, updating the criteria for deanships, and restructuring search committees. The barriers identified by the deans are similar to those found in previous studies on female faculty and department chairs, suggesting limited improvement in gender equity progress.

  19. Is natural defense capacity correlated with allocation of dry mass to the stem in loblolly pine?

    Treesearch

    Mary Anne Sword Sayer; Michael C. Tyree; Michael A. Blazier; Shi-Jean Susana Sung; Lori G. Eckhardt

    2016-01-01

    In addition to selecting loblolly pine (Pinus taeda L.) genotypes for superior growth, the concept of customized genetic selection may apply where tree vigor is threatened by insects and disease. A study conducted with seedlings from 15 loblolly pine genotypes found significant correlation between phenolic production and foliage mass when dry mass allocation to the...

  20. Optimal Computing Budget Allocation for Particle Swarm Optimization in Stochastic Optimization.

    PubMed

    Zhang, Si; Xu, Jie; Lee, Loo Hay; Chew, Ek Peng; Wong, Wai Peng; Chen, Chun-Hung

    2017-04-01

    Particle Swarm Optimization (PSO) is a popular metaheuristic for deterministic optimization. Originated in the interpretations of the movement of individuals in a bird flock or fish school, PSO introduces the concept of personal best and global best to simulate the pattern of searching for food by flocking and successfully translate the natural phenomena to the optimization of complex functions. Many real-life applications of PSO cope with stochastic problems. To solve a stochastic problem using PSO, a straightforward approach is to equally allocate computational effort among all particles and obtain the same number of samples of fitness values. This is not an efficient use of computational budget and leaves considerable room for improvement. This paper proposes a seamless integration of the concept of optimal computing budget allocation (OCBA) into PSO to improve the computational efficiency of PSO for stochastic optimization problems. We derive an asymptotically optimal allocation rule to intelligently determine the number of samples for all particles such that the PSO algorithm can efficiently select the personal best and global best when there is stochastic estimation noise in fitness values. We also propose an easy-to-implement sequential procedure. Numerical tests show that our new approach can obtain much better results using the same amount of computational effort.

  1. Optimal Computing Budget Allocation for Particle Swarm Optimization in Stochastic Optimization

    PubMed Central

    Zhang, Si; Xu, Jie; Lee, Loo Hay; Chew, Ek Peng; Chen, Chun-Hung

    2017-01-01

    Particle Swarm Optimization (PSO) is a popular metaheuristic for deterministic optimization. Originated in the interpretations of the movement of individuals in a bird flock or fish school, PSO introduces the concept of personal best and global best to simulate the pattern of searching for food by flocking and successfully translate the natural phenomena to the optimization of complex functions. Many real-life applications of PSO cope with stochastic problems. To solve a stochastic problem using PSO, a straightforward approach is to equally allocate computational effort among all particles and obtain the same number of samples of fitness values. This is not an efficient use of computational budget and leaves considerable room for improvement. This paper proposes a seamless integration of the concept of optimal computing budget allocation (OCBA) into PSO to improve the computational efficiency of PSO for stochastic optimization problems. We derive an asymptotically optimal allocation rule to intelligently determine the number of samples for all particles such that the PSO algorithm can efficiently select the personal best and global best when there is stochastic estimation noise in fitness values. We also propose an easy-to-implement sequential procedure. Numerical tests show that our new approach can obtain much better results using the same amount of computational effort. PMID:29170617

  2. Compartmentalization, resource allocation, and wood quality

    Treesearch

    Kevin T. Smith

    2015-01-01

    The concept of a trade-off of tree resources between growth and defense is readily grasped. The most detailed development of the concept is for the growth-differentiation balance hypothesis that predicts that resources for normal growth and primary metabolism are diverted to support plant defense and secondary or stress metabolism. This hypothesis has been applied to...

  3. Concepts and Principles for State-Level Higher Education Budgeting. ASHE 1984 Annual Meeting Paper.

    ERIC Educational Resources Information Center

    Jones, Dennis P.

    Basic concepts concerning state-level resource allocation to higher education are discussed. Attention is directed to principles of budgeting regardless of context, the pluralistic nature of higher education, characteristics of higher education production functions, and the typical form of the budget. In addition to the distribution of resources,…

  4. Allocation of substance use disorder patients to appropriate levels of care: feasibility of matching guidelines in routine practice in Dutch treatment centres.

    PubMed

    Merkx, Maarten J M; Schippers, Gerard M; Koeter, Maarten J W; Vuijk, Pieter Jelle; Oudejans, Suzan; de Vries, Carlijn C Q; van den Brink, Wim

    2007-03-01

    To examine the feasibility of implementing evidence-based guidelines for patient-treatment-matching to levels of care in two Dutch substance abuse treatment centres. Multi-centre observational follow-up study. Two large substance abuse treatment centres (SATCs). All 4394 referrals to the two SATCs in 2003. Baseline patient characteristics needed for treatment allocation according to protocol, treatment allocation according to matching protocol, treatment allocation according to actual level of care (LOC) entered. Comparison of recommended and actual LOC entered. Evaluation of reasons for observed differences between recommended and actual LOC entered. Data needed for treatment allocation according to protocol were available for 2269 (51.6%) patients. Data needed for evaluation of actual LOC entered were available for 1765 (40.2%) patients. Of these patients, 1089 (60.8%) were allocated according to protocol: 48.4% based on the guideline algorithm and 12.4% based on clinically justified deviations from this algorithm. The main reason for deviation was a different appraisal of addiction severity, made by the intake counsellor compared to the protocol. The feasibility of guideline-based treatment allocation is seriously limited due to inadequate data collection of patient characteristics and suboptimal guideline-based treatment allocation. As a consequence, only 24.4% of the patients could be evaluated as being matched properly to the treatment planned. The results indicate several barriers which limit the adequate implementation of patient-treatment-matching guidelines: problems in the infrastructure of data collection and storage and the inertia of intake staff who did not adhere to the guidelines for assessment and matching.

  5. Why do we have the kidney allocation system we have today? A history of the 2014 kidney allocation system.

    PubMed

    Stegall, Mark D; Stock, Peter G; Andreoni, Kenneth; Friedewald, John J; Leichtman, Alan B

    2017-01-01

    "Those who do not know the past are destined to repeat it". The current system for the allocation of deceased donor kidneys that was implemented in December 2014 (termed the kidney allocation system (KAS)) was the culmination of a decade-long process. Thus, many people involved in transplantation today may not be aware of the underlying concepts and early debates that resulted in KAS. Others who were involved might not remember the details (or have chosen to forget). The goal of this manuscript is to outline the history of the process in order to shed light on why KAS has its current format. Copyright © 2016 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

  6. Study of network resource allocation based on market and game theoretic mechanism

    NASA Astrophysics Data System (ADS)

    Liu, Yingmei; Wang, Hongwei; Wang, Gang

    2004-04-01

    We work on the network resource allocation issue concerning network management system function based on market-oriented mechanism. The scheme is to model the telecommunication network resources as trading goods in which the various network components could be owned by different competitive, real-world entities. This is a multidisciplinary framework concentrating on the similarity between resource allocation in network environment and the market mechanism in economic theory. By taking an economic (market-based and game theoretic) approach in routing of communication network, we study the dynamic behavior under game-theoretic framework in allocating network resources. Based on the prior work of Gibney and Jennings, we apply concepts of utility and fitness to the market mechanism with an intention to close the gap between experiment environment and real world situation.

  7. Using concept mapping in the knowledge-to-action process to compare stakeholder opinions on barriers to use of cancer screening among South Asians.

    PubMed

    Lobb, Rebecca; Pinto, Andrew D; Lofters, Aisha

    2013-03-23

    Using the knowledge-to-action (KTA) process, this study examined barriers to use of evidence-based interventions to improve early detection of cancer among South Asians from the perspective of multiple stakeholders. In 2011, we used concept mapping with South Asian residents, and representatives from health service and community service organizations in the region of Peel Ontario. As part of concept mapping procedures, brainstorming sessions were conducted with stakeholders (n = 53) to identify barriers to cancer screening among South Asians. Participants (n = 46) sorted barriers into groups, and rated barriers from lowest (1) to highest (6) in terms of importance for use of mammograms, Pap tests and fecal occult blood tests, and how feasible it would be to address them. Multi-dimensional scaling, cluster analysis, and descriptive statistics were used to analyze the data. A total of 45 unique barriers to use of mammograms, Pap tests, and fecal occult blood tests among South Asians were classified into seven clusters using concept mapping procedures: patient's beliefs, fears, lack of social support; health system; limited knowledge among residents; limited knowledge among physicians; health education programs; ethno-cultural discordance with the health system; and cost. Overall, the top three ranked clusters of barriers were 'limited knowledge among residents,' 'ethno-cultural discordance,' and 'health education programs' across surveys. Only residents ranked 'cost' second in importance for fecal occult blood testing, and stakeholders from health service organizations ranked 'limited knowledge among physicians' third for the feasibility survey. Stakeholders from health services organizations ranked 'limited knowledge among physicians' fourth for all other surveys, but this cluster consistently ranked lowest among residents. The limited reach of cancer control programs to racial and ethnic minority groups is a critical implementation issue that requires attention. Opinions of community service and health service organizations on why this deficit in implementation occurs are fundamental to understanding the solutions because these are the settings in which evidence-based interventions are implemented. Using concept mapping within a KTA process can facilitate the engagement of multiple stakeholders in the utilization of study results and in identifying next steps for action.

  8. Shorebird and boater impact management planning

    Treesearch

    Robert D. Deblinger; Jerry J. Vaske; Maureen P. Donnelly; Russ Hopping

    1992-01-01

    This paper integrates social and ecological impact data from a barrier beach to demonstrate the value of an inter-disciplinary approach to resource allocation and visitor management. The ecological data included observations of shorebird distributions and causes of human disturbance. The social data were obtained from on-site surveys of boaters and pedestrian visitors...

  9. A Balancing Act: School Budgeting and Resource Allocation on a New Dual Language Campus

    ERIC Educational Resources Information Center

    Knight, David S.; Izquierdo, Elena; DeMatthews, David E.

    2016-01-01

    Dual language instructional models have great potential to create inclusive learning environments for traditional under-served students and boost student outcomes. However, principals face many barriers to implementation. One of the key challenges is aligning resources to ensure that the school has (a) an appropriate number of certificated…

  10. Antecedents and Consequences of Career Decisional States in Adolescence

    ERIC Educational Resources Information Center

    Creed, Peter; Prideaux, Lee-Ann; Patton, Wendy

    2005-01-01

    This longitudinal study tested students in Grade 8 and again in Grade 10 on career (maturity, barriers, indecision, decision-making and self-efficacy), well-being (self-esteem, life satisfaction, and coping), and social (school achievement, paid work experience) variables. Students were allocated to decided or undecided conditions at T1, T2 and…

  11. Sustainability in Health care by Allocating Resources Effectively (SHARE) 10: operationalising disinvestment in a conceptual framework for resource allocation.

    PubMed

    Harris, Claire; Green, Sally; Elshaug, Adam G

    2017-09-08

    This is the tenth in a series of papers reporting a program of Sustainability in Health care by Allocating Resources Effectively (SHARE) in a local healthcare setting. After more than a decade of research, there is little published evidence of active and successful disinvestment. The paucity of frameworks, methods and tools is reported to be a factor in the lack of success. However there are clear and consistent messages in the literature that can be used to inform development of a framework for operationalising disinvestment. This paper, along with the conceptual review of disinvestment in Paper 9 of this series, aims to integrate the findings of the SHARE Program with the existing disinvestment literature to address the lack of information regarding systematic organisation-wide approaches to disinvestment at the local health service level. A framework for disinvestment in a local healthcare setting is proposed. Definitions for essential terms and key concepts underpinning the framework have been made explicit to address the lack of consistent terminology. Given the negative connotations of the word 'disinvestment' and the problems inherent in considering disinvestment in isolation, the basis for the proposed framework is 'resource allocation' to address the spectrum of decision-making from investment to disinvestment. The focus is positive: optimising healthcare, improving health outcomes, using resources effectively. The framework is based on three components: a program for decision-making, projects to implement decisions and evaluate outcomes, and research to understand and improve the program and project activities. The program consists of principles for decision-making and settings that provide opportunities to introduce systematic prompts and triggers to initiate disinvestment. The projects follow the steps in the disinvestment process. Potential methods and tools are presented, however the framework does not stipulate project design or conduct; allowing application of any theories, methods or tools at each step. Barriers are discussed and examples illustrating constituent elements are provided. The framework can be employed at network, institutional, departmental, ward or committee level. It is proposed as an organisation-wide application, embedded within existing systems and processes, which can be responsive to needs and priorities at the level of implementation. It can be used in policy, management or clinical contexts.

  12. Men, Women, and Equity

    ERIC Educational Resources Information Center

    Rapoport, Rhona; Rapoport, Robert N.

    1975-01-01

    The concept of equity is proposed as having advantages over that of equality. By equity, we mean a fair allocation both of opportunity and of constraints. It is put forward as a concept which goes beyond that of equality; it acknowledges differences between men and women and the need to think in terms of variations of patterns. Paper presented at…

  13. Function Allocation between Automation and Human Pilot for Airborne Separation Assurance

    NASA Technical Reports Server (NTRS)

    Idris, Husni; Enea, Gabriele; Lewis, TImothy A.

    2016-01-01

    Maintaining safe separation between aircraft is a key determinant of the airspace capacity to handle air transportation. With the advent of satellite-based surveillance, aircraft equipped with the needed technologies are now capable of maintaining awareness of their location in the airspace and sharing it with their surrounding traffic. As a result, concepts and cockpit automation are emerging to enable delegating the responsibility of maintaining safe separation from traffic to the pilot; thus increasing the airspace capacity by alleviating the limitation of the current non-scalable centralized ground-based system. In this paper, an analysis of allocating separation assurance functions to the human pilot and cockpit automation is presented to support the design of these concepts and technologies. A task analysis was conducted with the help of Petri nets to identify the main separation assurance functions and their interactions. Each function was characterized by three behavior levels that may be needed to perform the task: skill, rule and knowledge based levels. Then recommendations are made for allocating each function to an automation scale based on their behavior level characterization and with the help of Subject matter experts.

  14. Allocation of Functions in a Far-Term Air Traffic Control Environment

    NASA Technical Reports Server (NTRS)

    Homola, Jeffrey; Martin, Lynne; Mercer, Joey; Cabrall, Christopher; Prevot, Thomas

    2011-01-01

    A human-in-the-loop exploration of a ground-based automated separation assurance concept was conducted that involved the allocation of certain functions between humans and automation. This exploration included operations that were sustained for prolonged periods of time with high levels of traffic in the presence of convective weather and scheduling constraints. An investigation into the acceptability of the defined roles and performance of tasks was conducted where it was found that the participants rated the concept and allocation of functions with a high level of acceptability. However, issues were encountered with the automation related to the detection of and response to tactical conflicts. Lower ratings were given on account of these concerns, and it was found that a key contributor to the underlying problems was transitioning aircraft and the uncertainty of their trajectories. Stemming from those results, participants responded that they would rather have direct control over aircraft transitions as well as more control over the tactical conflict resolution automation. In contrast, participants responded that they would rather have the automation place aircraft back on trajectory, and perform weather avoidance and scheduling tasks.

  15. How to Help Your Students Recall New Concepts Better.

    ERIC Educational Resources Information Center

    Hodges, Daniel L.

    Students' difficulties in assimilating new concepts can be a barrier to learning and may be exacerbated if the concepts are introduced in terms of detailed verbal definitions. Cognitive psychology suggests that a better approach to teaching new concepts may be to use prototypical examples of the concept as building-blocks from which verbal…

  16. A review of alternative approaches to healthcare resource allocation.

    PubMed

    Petrou, S; Wolstenholme, J

    2000-07-01

    The resources available for healthcare are limited compared with demand, if not need, and all healthcare systems, regardless of their financing and organisation, employ mechanisms to ration or prioritise finite healthcare resources. This paper reviews alternative approaches that can be used to allocate healthcare resources. It discusses the problems encountered when allocating healthcare resources according to free market principles. It then proceeds to discuss the advantages and disadvantages of alternative resource allocation approaches that can be applied to public health systems. These include: (i) approaches based on the concept of meeting the needs of the population to maximising its capacity to benefit from interventions; (ii) economic approaches that identify the most efficient allocation of resources with the view of maximising health benefits or other measures of social welfare; (iii) approaches that seek to ration healthcare by age; and (iv) approaches that resolve resource allocation disputes through debate and bargaining. At present, there appears to be no consensus about the relative importance of the potentially conflicting principles that can be used to guide resource allocation decisions. It is concluded that whatever shape tomorrow's health service takes, the requirement to make equitable and efficient use of finite healthcare resources will remain.

  17. THE CONSEQUENCES OF CROSSING BARRIERS AND BOUNDARIES

    EPA Science Inventory

    This is a brief, general ecological theory presentation which explains concepts of physically defining habitational zones, ecological barriers, ecological boundaries and vehicles, plus biologically defining pathogens, hosts, and vectors.

  18. Health care in the developing world: the role of economists and economics.

    PubMed

    Lee, K

    1983-01-01

    This paper does not address itself to high theory or to complex methodologies; nor does it offer any detailed illumination of key economic concepts. Rather, it focuses on the role of economists and economics (not the same thing) in the formulation of health policies, and in influencing an evaluation of health strategies appropriate to the requirements of the developing world. The paper argues that the 'climate' has changed sufficiently in the developing world to promote a close interest in the economics of health and health care. Evidence exists of a growing willingness to employ economists and economic analysis to resource allocation issues within the health sector. Accordingly, a glossary of economic concepts in presented to demonstrate that economics does possess certain ideas, distinct from other disciplines, which can be of considerable value to health planners and health managers alike. The text also sets out, in tabular form, many of the key questions that should be of close interest to policy-makers, and indicates the economic concepts and techniques that can be applied. At the same time, it is noted that there are very real conceptual and methodological problems likely to be faced by those wishing to apply economic reasoning to the health sector. The paper then moves on from analysis to consider implementation, and investigates the political constraints and institutional barriers to the acceptance of economic analysis in the health sector. In the past, the nature of the economics of health has sometimes been considered improper, i.e. views have been expressed that services should be made available to those for whom they may be beneficial, as a matter of right without regard to economics.(ABSTRACT TRUNCATED AT 250 WORDS)

  19. Rethinking Reinforcement: Allocation, Induction, and Contingency

    PubMed Central

    Baum, William M

    2012-01-01

    The concept of reinforcement is at least incomplete and almost certainly incorrect. An alternative way of organizing our understanding of behavior may be built around three concepts: allocation, induction, and correlation. Allocation is the measure of behavior and captures the centrality of choice: All behavior entails choice and consists of choice. Allocation changes as a result of induction and correlation. The term induction covers phenomena such as adjunctive, interim, and terminal behavior—behavior induced in a situation by occurrence of food or another Phylogenetically Important Event (PIE) in that situation. Induction resembles stimulus control in that no one-to-one relation exists between induced behavior and the inducing event. If one allowed that some stimulus control were the result of phylogeny, then induction and stimulus control would be identical, and a PIE would resemble a discriminative stimulus. Much evidence supports the idea that a PIE induces all PIE-related activities. Research also supports the idea that stimuli correlated with PIEs become PIE-related conditional inducers. Contingencies create correlations between “operant” activity (e.g., lever pressing) and PIEs (e.g., food). Once an activity has become PIE-related, the PIE induces it along with other PIE-related activities. Contingencies also constrain possible performances. These constraints specify feedback functions, which explain phenomena such as the higher response rates on ratio schedules in comparison with interval schedules. Allocations that include a lot of operant activity are “selected” only in the sense that they generate more frequent occurrence of the PIE within the constraints of the situation; contingency and induction do the “selecting.” PMID:22287807

  20. A graphite-lined regeneratively cooled thrust chamber

    NASA Technical Reports Server (NTRS)

    Stubbs, V. R.

    1972-01-01

    Design concepts, based on use of graphite as a thermal barrier for regeneratively cooled FLOX-methane thrust chambers, have been screened and concepts selected for detailed thermodynamic, stress, and fabrication analyses. A single design employing AGCarb-101, a fibrous graphite composite material, for a thermal barrier liner and an electroformed nickel structure with integral coolant passages was selected for fabrication and testing. The fabrication processes and the test results are described and illustrated.

  1. Integrating the 3Ds: a nursing perspective.

    PubMed

    Villarruel, Antonia M; Bigelow, April; Alvarez, Carmen

    2014-01-01

    The 3Ds (diversity, disparities, and determinants) that serve as a framework for this supplement are concepts that are key foundations of nursing education, practice, and research. Despite this fact, however, the nursing profession has faced challenges recognizing the full potential of these concepts. While their importance is documented and acknowledged, they are not clearly evident or easily recognized within the nursing profession. In fact, there are many barriers to the integration of these concepts. We identify and address two barriers to addressing health disparities and increasing diversity: disconnects and discrimination. Furthermore, we discuss three factors-dissemination, durability, and data-that may facilitate nursing's efforts to integrate the 3Ds into the profession. Five pivotal models that address these barriers and facilitators are presented as exemplars that have the potential to guide efforts to address diversity, disparities, and social determinants of health and act as catalysts for change within the nursing profession.

  2. Integrating the 3Ds: A Nursing Perspective

    PubMed Central

    Bigelow, April; Alvarez, Carmen

    2014-01-01

    The 3Ds (diversity, disparities, and determinants) that serve as a framework for this supplement are concepts that are key foundations of nursing education, practice, and research. Despite this fact, however, the nursing profession has faced challenges recognizing the full potential of these concepts. While their importance is documented and acknowledged, they are not clearly evident or easily recognized within the nursing profession. In fact, there are many barriers to the integration of these concepts. We identify and address two barriers to addressing health disparities and increasing diversity: disconnects and discrimination. Furthermore, we discuss three factors—dissemination, durability, and data—that may facilitate nursing's efforts to integrate the 3Ds into the profession. Five pivotal models that address these barriers and facilitators are presented as exemplars that have the potential to guide efforts to address diversity, disparities, and social determinants of health and act as catalysts for change within the nursing profession. PMID:24385663

  3. Allocation Methods for Use in the Accrual of Manpower Costs.

    DTIC Science & Technology

    1983-06-01

    planners more frugal in their use of military manpower (OB1, 1973). Generally Accepted Accounting Principles ( GAAP ) recognize accrual basis accounting...time. Examples of this type of allocation are depreciation or amortization of long term assets (Fremgen and Liao, 1981). It is this second concept of...financing is that the relatively "soft dollars" of the future will make it easier to contribute. A "soft dollar" is the depreciated value of the dollar

  4. S4HARA: System for HIV/AIDS resource allocation.

    PubMed

    Lasry, Arielle; Carter, Michael W; Zaric, Gregory S

    2008-03-26

    HIV/AIDS resource allocation decisions are influenced by political, social, ethical and other factors that are difficult to quantify. Consequently, quantitative models of HIV/AIDS resource allocation have had limited impact on actual spending decisions. We propose a decision-support System for HIV/AIDS Resource Allocation (S4HARA) that takes into consideration both principles of efficient resource allocation and the role of non-quantifiable influences on the decision-making process for resource allocation. S4HARA is a four-step spreadsheet-based model. The first step serves to identify the factors currently influencing HIV/AIDS allocation decisions. The second step consists of prioritizing HIV/AIDS interventions. The third step involves allocating the budget to the HIV/AIDS interventions using a rational approach. Decision-makers can select from several rational models of resource allocation depending on availability of data and level of complexity. The last step combines the results of the first and third steps to highlight the influencing factors that act as barriers or facilitators to the results suggested by the rational resource allocation approach. Actionable recommendations are then made to improve the allocation. We illustrate S4HARA in the context of a primary healthcare clinic in South Africa. The clinic offers six types of HIV/AIDS interventions and spends US$750,000 annually on these programs. Current allocation decisions are influenced by donors, NGOs and the government as well as by ethical and religious factors. Without additional funding, an optimal allocation of the total budget suggests that the portion allotted to condom distribution be increased from 1% to 15% and the portion allotted to prevention and treatment of opportunistic infections be increased from 43% to 71%, while allocation to other interventions should decrease. Condom uptake at the clinic should be increased by changing the condom distribution policy from a pull system to a push system. NGOs and donors promoting antiretroviral programs at the clinic should be sensitized to the results of the model and urged to invest in wellness programs aimed at the prevention and treatment of opportunistic infections. S4HARA differentiates itself from other decision support tools by providing rational HIV/AIDS resource allocation capabilities as well as consideration of the realities facing authorities in their decision-making process.

  5. Political Barriers to Evidence-Based Tobacco Control Policy: Cronyism and Cognitive Dissonance, a Tasmanian Case Study

    ERIC Educational Resources Information Center

    Barnsley, Kathryn; Walters, E. Haydn; Wood-Baker, Richard

    2017-01-01

    Tasmania led in several areas of tobacco control legislation reform in the period 1997 to 2010. Despite this, Tasmania lagged in other crucial areas, particularly the allocation of resources for community education, mass media campaigns and cessation programmes. Key impediments were crony capitalism; the conservative ideology of "white…

  6. Paper-Based and Computer-Based Concept Mappings: The Effects on Computer Achievement, Computer Anxiety and Computer Attitude

    ERIC Educational Resources Information Center

    Erdogan, Yavuz

    2009-01-01

    The purpose of this paper is to compare the effects of paper-based and computer-based concept mappings on computer hardware achievement, computer anxiety and computer attitude of the eight grade secondary school students. The students were randomly allocated to three groups and were given instruction on computer hardware. The teaching methods used…

  7. Making the Economic Concept of Scarcity Oh-so-Sweet: An Activity for the K-12 Classroom

    ERIC Educational Resources Information Center

    Marks, Melanie; Davis, Cheryl

    2006-01-01

    The authors outline an innovative activity that helps teachers make the abstract concepts of scarcity and allocation concrete in the K-12 classroom. Students evaluate the scarcity of chocolate and often determine, incorrectly, that the candy is not scarce because there is enough for each student to have one piece. After students reveal their…

  8. A Review of Function Allocation and En Route Separation Assurance

    NASA Technical Reports Server (NTRS)

    Lewis, Timothy A.; Aweiss, Arwa S.; Guerreiro, Nelson M.; Daiker, Ronald J.

    2016-01-01

    Today's air traffic control system has reached a limit to the number of aircraft that can be safely managed at the same time. This air traffic capacity bottleneck is a critical problem along the path to modernization for air transportation. The design of the next separation assurance system to address this problem is a cornerstone of air traffic management research today. This report reviews recent work by NASA and others in the areas of function allocation and en route separation assurance. This includes: separation assurance algorithms and technology prototypes; concepts of operations and designs for advanced separation assurance systems; and specific investigations into air-ground and human-automation function allocation.

  9. Electronic health records: what are the most important barriers?

    PubMed

    Ayatollahi, Haleh; Mirani, Nader; Haghani, Hamid

    2014-01-01

    The process of design and adoption of electronic health records may face a number of barriers. This study aimed to compare the importance of the main barriers from the experts' point of views in Iran. This survey study was completed in 2011. The potential participants (62 experts) included faculty members who worked in departments of health information technology and individuals who worked in the Ministry of Health in Iran and were in charge of the development and adoption of electronic health records. No sampling method was used in this study. Data were collected using a Likert-scale questionnaire ranging from 1 to 5. The validity of the questionnaire was established using content and face validity methods, and the reliability was calculated using Cronbach's alpha coefficient. The response rate was 51.6 percent. The participants' perspectives showed that the most important barriers in the process of design and adoption of electronic health records were technical barriers (mean = 3.84). Financial and ethical-legal barriers, with the mean value of 3.80 were other important barriers, and individual and organizational barriers, with the mean values of 3.59 and 3.50 were found to be less important than other barriers from the experts' perspectives. Strategic planning for the creation and adoption of electronic health records in the country, creating a team of experts to assess the potential barriers and develop strategies to eliminate them, and allocating financial resources can help to overcome most important barriers to the adoption of electronic health records.

  10. Benefits Assessment of the Interaction Between Traffic Flow Management Delay and Airspace Partitions in the Presence of Weather

    NASA Technical Reports Server (NTRS)

    Palopo, Kee; Lee, Hak-Tae; Chatterji, Gano

    2011-01-01

    The concept of re-partitioning the airspace into a new set of sectors for allocating capacity rather than delaying flights to comply with the capacity constraints of a static set of sectors is being explored. The reduction in delay, a benefit, achieved by this concept needs to be greater than the cost of controllers and equipment needed for the additional sectors. Therefore, tradeoff studies are needed for benefits assessment of this concept.

  11. Explanation of the barrier heights of graphene Schottky contacts by the MIGS-and-electronegativity concept

    NASA Astrophysics Data System (ADS)

    Mönch, Winfried

    2016-09-01

    Graphene-semiconductor contacts exhibit rectifying properties and, in this respect, they behave in exactly the same way as a "conventional" metal-semiconductor or Schottky contacts. It will be demonstrated that, as often assumed, the Schottky-Mott rule does not describe the reported barrier heights of graphene-semiconductor contacts. With "conventional" Schottky contacts, the same conclusion was reached already in 1940. The physical reason is that the Schottky-Mott rule considers no interaction between the metal and the semiconductor. The barrier heights of "conventional" Schottky contacts were explained by the continuum of metal-induced gap states (MIGSs), where the differences of the metal and semiconductor electronegativities describe the size and the sign of the intrinsic electric-dipoles at the interfaces. It is demonstrated that the MIGS-and-electronegativity concept unambiguously also explains the experimentally observed barrier heights of graphene Schottky contacts. This conclusion includes also the barrier heights reported for MoS2 Schottky contacts with "conventional" metals as well as with graphene.

  12. The DSN view periods for a mission

    NASA Technical Reports Server (NTRS)

    Kehrbaum, J. M.; Kim, K.

    2002-01-01

    The Jet Propulsion Laboratory Resource Allocation, Planning and Scheduling Office (JPL-RAPSO) is chartered to allocate the limited amount of tracking hours among the various missions in as equitable allotment as can be achieved. The communication windows that can be used for communication between the ground and the Project/spacecraft are called 'viewperiods.' The concept of the viewperiods for (any) mission is presented in this paper, along with the levels of refinement over time (Forecasting/Project/Mid- Range/NSS) associated with those viewperiods.

  13. Army Training Study: Concepts of the Army Training System.

    DTIC Science & Technology

    1978-08-08

    Act Amendments of 1949, (Public l-w 2 , wh{.’ led to needed imrovements in the financial management of the militarv services. National Securitv Act...F40 1949 (Public Law 216), C3 Amount of authorized IDT, F5 Appropriation system, C4 Annual training time (AT), F5, F30 Financial management , C3 Basic...Where should it be allocated? Since allocation cf resources occurs at different levels of management , the Army must be sensitive to the comparability of

  14. Synergistic Allocation of Flight Expertise on the Flight Deck (SAFEdeck): A Design Concept to Combat Mode Confusion, Complacency, and Skill Loss in the Flight Deck

    NASA Technical Reports Server (NTRS)

    Schutte, Paul; Goodrich, Kenneth; Williams, Ralph

    2016-01-01

    This paper presents a new design and function allocation philosophy between pilots and automation that seeks to support the human in mitigating innate weaknesses (e.g., memory, vigilance) while enhancing their strengths (e.g., adaptability, resourcefulness). In this new allocation strategy, called Synergistic Allocation of Flight Expertise in the Flight Deck (SAFEdeck), the automation and the human provide complementary support and backup for each other. Automation is designed to be compliant with the practices of Crew Resource Management. The human takes a more active role in the normal operation of the aircraft without adversely increasing workload over the current automation paradigm. This designed involvement encourages the pilot to be engaged and ready to respond to unexpected situations. As such, the human may be less prone to error than the current automation paradigm.

  15. Decision-theoretic methodology for reliability and risk allocation in nuclear power plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cho, N.Z.; Papazoglou, I.A.; Bari, R.A.

    1985-01-01

    This paper describes a methodology for allocating reliability and risk to various reactor systems, subsystems, components, operations, and structures in a consistent manner, based on a set of global safety criteria which are not rigid. The problem is formulated as a multiattribute decision analysis paradigm; the multiobjective optimization, which is performed on a PRA model and reliability cost functions, serves as the guiding principle for reliability and risk allocation. The concept of noninferiority is used in the multiobjective optimization problem. Finding the noninferior solution set is the main theme of the current approach. The assessment of the decision maker's preferencesmore » could then be performed more easily on the noninferior solution set. Some results of the methodology applications to a nontrivial risk model are provided and several outstanding issues such as generic allocation and preference assessment are discussed.« less

  16. The role of intrinsic motivations in attention allocation and shifting

    PubMed Central

    Di Nocera, Dario; Finzi, Alberto; Rossi, Silvia; Staffa, Mariacarla

    2014-01-01

    The concepts of attention and intrinsic motivations are of great interest within adaptive robotic systems, and can be exploited in order to guide, activate, and coordinate multiple concurrent behaviors. Attention allocation strategies represent key capabilities of human beings, which are strictly connected with action selection and execution mechanisms, while intrinsic motivations directly affect the allocation of attentional resources. In this paper we propose a model of Reinforcement Learning (RL), where both these capabilities are involved. RL is deployed to learn how to allocate attentional resources in a behavior-based robotic system, while action selection is obtained as a side effect of the resulting motivated attentional behaviors. Moreover, the influence of intrinsic motivations in attention orientation is obtained by introducing rewards associated with curiosity drives. In this way, the learning process is affected not only by goal-specific rewards, but also by intrinsic motivations. PMID:24744746

  17. Funding Based on Needs? A Study on the Use of Needs Assessment Data by a Major Humanitarian Health Assistance Donor in its Decisions to Allocate Funds

    PubMed Central

    Olin, Emma; von Schreeb, Johan

    2014-01-01

    Background: International humanitarian assistance is essential for disaster-affected populations, particularly in resource scarce settings. To target such assistance, needs assessments are required. According to internationally endorsed principles, donor governments should provide funding for humanitarian assistance based on need. Aim: The aim of this study is to explore a major donor’s use of needs assessment data in decision-making for allocations of funds for health-related humanitarian assistance contributions. Setting: This is a case study of the Swedish International Development Cooperation Agency (Sida), a major and respected international donor of humanitarian assistance. Methods: To explore Sida’s use of needs assessment data in practice for needs-based allocations, we reviewed all decision documents and assessment memoranda for humanitarian assistance contributions for 2012 using content analysis; this was followed by interviews with key personnel at Sida. Results: Our document analysis found that needs assessment data was not systematically included in Sida’s assessment memoranda and decision documents. In the interviews, we observed various descriptions of the concept of needs assessments, the importance of contextual influences as well as previous collaborations with implementing humanitarian assistance organizations. Our findings indicate that policies guiding funding decisions on humanitarian assistance need to be matched with available needs assessment data and that terminologies and concepts have to be clearly defined. Conclusion: Based on the document analysis and the interviews, it is unclear how well Sida used needs assessment data for decisions to allocate funds. However, although our observations show that needs assessments are seldom used in decision making, Sida’s use of needs assessments has improved compared to a previous study. To improve project funds allocations based on needs assessment data, it will be critical to develop distinct frameworks for allocation distributions based on needs assessment and clear definitions, measurements and interpretations of needs. Key words: Needs assessment, humanitarian assistance, disasters, donor decision-making PMID:24894417

  18. Counterinsurgency After Afghanistan: A Concept in Crisis

    DTIC Science & Technology

    2011-12-01

    in strategy was undeniably stabilizing. This also explains the concrete walls, barriers, check- points, and other population-control measures...partnering with Sunni community leaders, Dagger Brigade was able to interpose itself—with concrete barriers, combined outposts, and checkpoints...local forces work together toward the same end. Also important in this regard are the aforementioned check- points, concrete barriers, and other

  19. The Cool Club: Creating engaging, experimental and creative encounters between young minds and polar researchers at SPRI

    NASA Astrophysics Data System (ADS)

    Weeks, S. M.; Pope, A.

    2011-12-01

    Whilst the scientific case for current climate change is compelling, the consequences of climate change have largely failed to permeate through to individuals. This lack of public awareness of the science and the potential impacts could be considered a key obstacle to action. The possible reasons for such limited success centre on the issue that climate change is a complex subject, and that a wide ranging academic, political and social research literature on the science and wider implications of climate change has failed to communicate the key issues in an accessible way. These failures to adequately communicate both the science and the social science of climate change at a number of levels results in ';communication gaps' that act as fundamental barriers to both understanding and engagement with the issue. Meyer and Land (2003) suggest that learners can find certain ideas and concepts within a discipline difficult to understand and these act as a barrier to deeper understanding of a subject. To move beyond these threshold concepts, they suggest that the expert needs to support the learner through a range of learning experiences that allows the development of learning strategies particular to the individual. Meyer and Land's research into these threshold concepts has been situated within Economics, but has been suggested to be more widely applicable though there has been no attempt to either define or evaluate threshold concepts to climate change science. By identifying whether common threshold concepts exist specifically in climate science for cohorts of either formal or informal learners, scientists will be better able to support the public in understanding these concepts by changing how the knowledge is communicated to help overcome these barriers to learning. This paper reports on the findings of a study that examined the role of threshold concepts as barriers to understanding climate science in a UK University and considers its implications for wider scientific engagement with the public to develop climate literacy. The analysis of 3 successive cohorts of students' journals who followed the same degree module identified that threshold concepts do exist within the field, such as those related to: role of ocean circulation, use of proxy indicators, forcing factors and feedback mechanisms. Once identified, the study looked at possible strategies to overcome these barriers to support student climate literacy. It concluded that the use of threshold concepts could be problematic when trying to improve climate literacy, as each individual has their own concepts they find ';troublesome' that do not necessarily relate to others. For scientists this presents the difficulty of how to develop a strategy that supports the individual that is cost and time effective. However, the study identifies that eLearning can be used effectively to help people understand troublesome knowledge.

  20. Comparison of Airborne and Ground-Based Function Allocation Concepts for NextGen Using Human-In-The-Loop Simulations

    NASA Technical Reports Server (NTRS)

    Wing, David J.; Prevot, Thomas; Murdoch, Jennifer L.; Cabrall, Christopher D.; Homola, Jeffrey R.; Martin, Lynne H.; Mercer, Joey S.; Hoadley, Sherwood T.; Wilson, Sara R.; Hubbs, Clay E.; hide

    2010-01-01

    This paper presents an air/ground functional allocation experiment conducted by the National Aeronautics and Space Administration (NASA) using two human-in-the-Loop simulations to compare airborne and ground-based approaches to NextGen separation assurance. The approaches under investigation are two trajectory-based four-dimensional (4D) concepts; one referred to as "airborne trajectory management with self-separation" (airborne) the other as "ground-based automated separation assurance" (ground-based). In coordinated simulations at NASA's Ames and Langley Research Centers, the primary operational participants -controllers for the ground-based concept and pilots for the airborne concept - manage the same traffic scenario using the two different 4D concepts. The common scenarios are anchored in traffic problems that require a significant increase in airspace capacity - on average, double, and in some local areas, close to 250% over current day levels - in order to enable aircraft to safely and efficiently traverse the test airspace. The simulations vary common independent variables such as traffic density, sequencing and scheduling constraints, and timing of trajectory change events. A set of common metrics is collected to enable a direct comparison of relevant results. The simulations will be conducted in spring 2010. If accepted, this paper will be the first publication of the experimental approach and early results. An initial comparison of safety and efficiency as well as operator acceptability under the two concepts is expected.

  1. Concept for individualized patient allocation: ReCompare--remote comparison of particle and photon treatment plans.

    PubMed

    Lühr, Armin; Löck, Steffen; Roth, Klaus; Helmbrecht, Stephan; Jakobi, Annika; Petersen, Jørgen B; Just, Uwe; Krause, Mechthild; Enghardt, Wolfgang; Baumann, Michael

    2014-02-18

    Identifying those patients who have a higher chance to be cured with fewer side effects by particle beam therapy than by state-of-the-art photon therapy is essential to guarantee a fair and sufficient access to specialized radiotherapy. The individualized identification requires initiatives by particle as well as non-particle radiotherapy centers to form networks, to establish procedures for the decision process, and to implement means for the remote exchange of relevant patient information. In this work, we want to contribute a practical concept that addresses these requirements. We proposed a concept for individualized patient allocation to photon or particle beam therapy at a non-particle radiotherapy institution that bases on remote treatment plan comparison. We translated this concept into the web-based software tool ReCompare (REmote COMparison of PARticlE and photon treatment plans). We substantiated the feasibility of the proposed concept by demonstrating remote exchange of treatment plans between radiotherapy institutions and the direct comparison of photon and particle treatment plans in photon treatment planning systems. ReCompare worked with several tested standard treatment planning systems, ensured patient data protection, and integrated in the clinical workflow. Our concept supports non-particle radiotherapy institutions with the patient-specific treatment decision on the optimal irradiation modality by providing expertise from a particle therapy center. The software tool ReCompare may help to improve and standardize this personalized treatment decision. It will be available from our website when proton therapy is operational at our facility.

  2. 26 CFR 1.190-1 - Expenditures to remove architectural and transportation barriers to the handicapped and elderly.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... capital expenditures and are adjustments to basis under section 1016(a). A partner must combine his... appropriate adjustment to the basis of the relevant partnership property under section 1016. For purposes of... he elects to deduct. A allocates $10,000 of his $25,000 limitation to his distributive share of the...

  3. 26 CFR 1.190-1 - Expenditures to remove architectural and transportation barriers to the handicapped and elderly.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... capital expenditures and are adjustments to basis under section 1016(a). A partner must combine his... appropriate adjustment to the basis of the relevant partnership property under section 1016. For purposes of... he elects to deduct. A allocates $10,000 of his $25,000 limitation to his distributive share of the...

  4. HSI top-down requirements analysis for ship manpower reduction

    NASA Astrophysics Data System (ADS)

    Malone, Thomas B.; Bost, J. R.

    2000-11-01

    U.S. Navy ship acquisition programs such as DD 21 and CVNX are increasingly relying on top down requirements analysis (TDRA) to define and assess design approaches for workload and manpower reduction, and for ensuring required levels of human performance, reliability, safety, and quality of life at sea. The human systems integration (HSI) approach to TDRA begins with a function analysis which identifies the functions derived from the requirements in the Operational Requirements Document (ORD). The function analysis serves as the function baseline for the ship, and also supports the definition of RDT&E and Total Ownership Cost requirements. A mission analysis is then conducted to identify mission scenarios, again based on requirements in the ORD, and the Design Reference Mission (DRM). This is followed by a mission/function analysis which establishes the function requirements to successfully perform the ship's missions. Function requirements of major importance for HSI are information, performance, decision, and support requirements associated with each function. An allocation of functions defines the roles of humans and automation in performing the functions associated with a mission. Alternate design concepts, based on function allocation strategies, are then described, and task networks associated with the concepts are developed. Task network simulations are conducted to assess workloads and human performance capabilities associated with alternate concepts. An assessment of the affordability and risk associated with alternate concepts is performed, and manning estimates are developed for feasible design concepts.

  5. Effective teaching and feedback strategies in the or and beyond.

    PubMed

    Champagne, Bradley J

    2013-12-01

    Maintaining a standard of excellence for graduating surgical residents requires a comprehensive and consistent approach to surgical education. The omnipresent and increasing barriers to education must also be recognized and addressed. The implementation of effective teaching strategies is largely dependent on the resources available at each institution and the vision of education. Unfortunately, allocating time for surgeons to teach both inside and outside the operating room has become a foreign concept to administration. Furthermore, the reduction in case numbers performed by trainees now demands "quality over quantity" to ensure success. Quality teaching moments will only be realized when emphasis is placed on preparation, useful instruction during the procedure, and postoperative feedback. Ideal preparation entails a detailed discussion between the trainee and surgeon about the specific learning goals for the case. During the procedure, the faculty surgeon must strive to maximize the experience through effective communication while performing an efficient and safe operation. Numerous validated objective assessment tools exist for postprocedure evaluation but are grossly underutilized. Surgical education must thoughtfully be approached with the same fervor and detail as patient care. As faculty, it is our responsibility to train the next generation of surgeons and therefore "every case must count."

  6. Effective Teaching and Feedback Strategies in the OR and Beyond

    PubMed Central

    Champagne, Bradley J.

    2013-01-01

    Maintaining a standard of excellence for graduating surgical residents requires a comprehensive and consistent approach to surgical education. The omnipresent and increasing barriers to education must also be recognized and addressed. The implementation of effective teaching strategies is largely dependent on the resources available at each institution and the vision of education. Unfortunately, allocating time for surgeons to teach both inside and outside the operating room has become a foreign concept to administration. Furthermore, the reduction in case numbers performed by trainees now demands “quality over quantity” to ensure success. Quality teaching moments will only be realized when emphasis is placed on preparation, useful instruction during the procedure, and postoperative feedback. Ideal preparation entails a detailed discussion between the trainee and surgeon about the specific learning goals for the case. During the procedure, the faculty surgeon must strive to maximize the experience through effective communication while performing an efficient and safe operation. Numerous validated objective assessment tools exist for postprocedure evaluation but are grossly underutilized. Surgical education must thoughtfully be approached with the same fervor and detail as patient care. As faculty, it is our responsibility to train the next generation of surgeons and therefore “every case must count.” PMID:24436685

  7. STAR--people-powered prioritization: a 21st-century solution to allocation headaches.

    PubMed

    Airoldi, Mara; Morton, Alec; Smith, Jenifer A E; Bevan, Gwyn

    2014-11-01

    The aim of cost effectiveness analysis (CEA) is to inform the allocation of scarce resources. CEA is routinely used in assessing the cost-effectiveness of specific health technologies by agencies such as the National Institute for Health and Clinical Excellence (NICE) in England and Wales. But there is extensive evidence that because of barriers of accessibility and acceptability, CEA has not been used by local health planners in their annual task of allocating fixed budgets to a wide range of types of health care. This paper argues that these planners can use Socio Technical Allocation of Resources (STAR) for that task. STAR builds on the principles of CEA and the practice of program budgeting and marginal analysis. STAR uses requisite models to assess the cost-effectiveness of all interventions considered for resource reallocation by explicitly applying the theory of health economics to evidence of scale, costs, and benefits, with deliberation facilitated through an interactive social process of engaging key stakeholders. In that social process, the stakeholders generate missing estimates of scale, costs, and benefits of the interventions; develop visual models of their relative cost-effectiveness; and interpret the results. We demonstrate the feasibility of STAR by showing how it was used by a local health planning agency of the English National Health Service, the Isle of Wight Primary Care Trust, to allocate a fixed budget in 2008 and 2009. © The Author(s) 2014.

  8. Object oriented design (OOD) in real-time hardware-in-the-loop (HWIL) simulations

    NASA Astrophysics Data System (ADS)

    Morris, Joe; Richard, Henri; Lowman, Alan; Youngren, Rob

    2006-05-01

    Using Object Oriented Design (OOD) concepts in AMRDEC's Hardware-in-the Loop (HWIL) real-time simulations allows the user to interchange parts of the simulation to meet test requirements. A large-scale three-spectral band simulator connected via a high speed reflective memory ring for time-critical data transfers to PC controllers connected by non real-time Ethernet protocols is used to separate software objects from logical entities close to their respective controlled hardware. Each standalone object does its own dynamic initialization, real-time processing, and end of run processing; therefore it can be easily maintained and updated. A Resource Allocation Program (RAP) is also utilized along with a device table to allocate, organize, and document the communication protocol between the software and hardware components. A GUI display program lists all allocations and deallocations of HWIL memory and hardware resources. This interactive program is also used to clean up defunct allocations of dead processes. Three examples are presented using the OOD and RAP concepts. The first is the control of an ACUTRONICS built three-axis flight table using the same control for calibration and real-time functions. The second is the transportability of a six-degree-of-freedom (6-DOF) simulation from an Onyx residence to a Linux-PC. The third is the replacement of the 6-DOF simulation with a replay program to drive the facility with archived run data for demonstration or analysis purposes.

  9. Sharing Resources In Mobile/Satellite Communications

    NASA Technical Reports Server (NTRS)

    Yan, Tsun-Yee; Sue, Miles K.

    1992-01-01

    Report presents preliminary theoretical analysis of several alternative schemes for allocation of satellite resource among terrestrial subscribers of landmobile/satellite communication system. Demand-access and random-access approaches under code-division and frequency-division concepts compared.

  10. Cross-layer Joint Relay Selection and Power Allocation Scheme for Cooperative Relaying System

    NASA Astrophysics Data System (ADS)

    Zhi, Hui; He, Mengmeng; Wang, Feiyue; Huang, Ziju

    2018-03-01

    A novel cross-layer joint relay selection and power allocation (CL-JRSPA) scheme over physical layer and data-link layer is proposed for cooperative relaying system in this paper. Our goal is finding the optimal relay selection and power allocation scheme to maximize system achievable rate when satisfying total transmit power constraint in physical layer and statistical delay quality-of-service (QoS) demand in data-link layer. Using the concept of effective capacity (EC), our goal can be formulated into an optimal joint relay selection and power allocation (JRSPA) problem to maximize the EC when satisfying total transmit power limitation. We first solving optimal power allocation (PA) problem with Lagrange multiplier approach, and then solving optimal relay selection (RS) problem. Simulation results demonstrate that CL-JRSPA scheme gets larger EC than other schemes when satisfying delay QoS demand. In addition, the proposed CL-JRSPA scheme achieves the maximal EC when relay located approximately halfway between source and destination, and EC becomes smaller when the QoS exponent becomes larger.

  11. Sharing the cost of river basin adaptation portfolios to climate change: Insights from social justice and cooperative game theory

    NASA Astrophysics Data System (ADS)

    Girard, Corentin; Rinaudo, Jean-Daniel; Pulido-Velazquez, Manuel

    2016-10-01

    The adaptation of water resource systems to the potential impacts of climate change requires mixed portfolios of supply and demand adaptation measures. The issue is not only to select efficient, robust, and flexible adaptation portfolios but also to find equitable strategies of cost allocation among the stakeholders. Our work addresses such cost allocation problems by applying two different theoretical approaches: social justice and cooperative game theory in a real case study. First of all, a cost-effective portfolio of adaptation measures at the basin scale is selected using a least-cost optimization model. Cost allocation solutions are then defined based on economic rationality concepts from cooperative game theory (the Core). Second, interviews are conducted to characterize stakeholders' perceptions of social justice principles associated with the definition of alternatives cost allocation rules. The comparison of the cost allocation scenarios leads to contrasted insights in order to inform the decision-making process at the river basin scale and potentially reap the efficiency gains from cooperation in the design of river basin adaptation portfolios.

  12. Robust allocation of a defensive budget considering an attacker's private information.

    PubMed

    Nikoofal, Mohammad E; Zhuang, Jun

    2012-05-01

    Attackers' private information is one of the main issues in defensive resource allocation games in homeland security. The outcome of a defense resource allocation decision critically depends on the accuracy of estimations about the attacker's attributes. However, terrorists' goals may be unknown to the defender, necessitating robust decisions by the defender. This article develops a robust-optimization game-theoretical model for identifying optimal defense resource allocation strategies for a rational defender facing a strategic attacker while the attacker's valuation of targets, being the most critical attribute of the attacker, is unknown but belongs to bounded distribution-free intervals. To our best knowledge, no previous research has applied robust optimization in homeland security resource allocation when uncertainty is defined in bounded distribution-free intervals. The key features of our model include (1) modeling uncertainty in attackers' attributes, where uncertainty is characterized by bounded intervals; (2) finding the robust-optimization equilibrium for the defender using concepts dealing with budget of uncertainty and price of robustness; and (3) applying the proposed model to real data. © 2011 Society for Risk Analysis.

  13. Australasian emergency physicians: a learning and educational needs analysis. Part five: barriers to CPD experienced by FACEM, and attitudes to the ACEM MOPS programme.

    PubMed

    Dent, Andrew W; Weiland, Tracey J; Paltridge, Debbie

    2008-08-01

    To determine the barriers to continuous professional development (CPD) perceived by Fellows of the Australasian College for Emergency Medicine (FACEM), their opinions on the maintenance of professional standards programme (MOPS), and other aspects of education. Mailed survey offering 12 factors that could prevent them from participating in CPD. FACEM were asked to rate the items on Likert from 1, no barrier, through to 5, insurmountable barrier. Qualitative comments on barriers, MOPS and other education were grouped. Nearly 47% of FACEM nominated lack of time with too many other priorities as significant of insurmountable barriers to CPD whilst 41% cited their ED as being too busy to leave and 35% had family commitments preventing CPD. While commitments, resistance from colleagues or employers (7%), lack of personal motivation or interest, (7.5%) lack of conference leave (8%) or financial restraint (14.5%) were lesser barriers for FACEM. Scheduling at inconvenient times (25%) and geographical factors (19%) were also perceived as significant barriers. Analysis of qualitative responses highlighted staff shortages, family reasons, personal fatigue, lack of interest in available CPD, cost and limited nonclinical time as being important barriers for some FACEM. Less than 50% of FACEM agreed that current allocation of MOPS points was appropriate or that the website spot diagnoses and scenarios kept their knowledge current. Nearly 28% did not find online MOPS easy to comprehend. These findings may assist in facilitating increased participation in CPD by FACEM.

  14. WATER QUALITY IN SOURCE WATER, TREATMENT, AND DISTRIBUTION SYSTEMS

    EPA Science Inventory

    Most drinking water utilities practice the multiple-barrier concept as the guiding principle for providing safe water. This chapter discusses multiple barriers as they relate to the basic criteria for selecting and protecting source waters, including known and potential sources ...

  15. Management by Trajectory Trade Study of Roles and Responsibilities Between Participants and Automation Report

    NASA Technical Reports Server (NTRS)

    Fernandes, Alicia D.; Kaler, Curt; Leiden, Kenneth; Atkins, Stephen; Bell, Alan; Kilbourne, Todd; Evans, Mark

    2017-01-01

    This report describes a trade study of roles and responsibilities associated with the Management by Trajectory (MBT) concept. The MBT concept describes roles, responsibilities, and information and automation requirements for providing air traffic controllers and managers the ability to quickly generate, evaluate and implement changes to an aircraft's trajectory. In addition, the MBT concept describes mechanisms for imposing constraints on flight operator preferred trajectories only to the extent necessary to maintain safe and efficient traffic flows, and the concept provides a method for the exchange of trajectory information between ground automation systems and the aircraft that allows for trajectory synchronization and trajectory negotiation. The participant roles considered in this trade study include: airline dispatcher, flight crew, radar controller, traffic manager, and Air Traffic Control System Command Center (ATCSCC) traffic management specialists. The proposed allocation of roles and responsibilities was based on analysis of several use cases that were developed for this purpose as well as for walking through concept elements. The resulting allocation of roles and responsibilities reflects both increased automation capability to support many aviation functions, as well as increased flexibility to assign responsibilities to different participants - in many cases afforded by the increased automation capabilities. Note that the selection of participants to consider for allocation of each function is necessarily rooted in the current environment, in that MBT is envisioned as an evolution of the National Airspace System (NAS), and not a revolution. A key feature of the MBT allocations is a vision for the traffic management specialist to take on a greater role. This is facilitated by the vision that separation management functions, in addition to traffic management functions, will be carried out as trajectory management functions. This creates an opportunity for flexibility, allowing the traffic management specialist to carry out tasks that today can only be carried out by the controller currently in contact with the aircraft. This additional tasking for the traffic management specialist comes with requirements for workload management. An increased role for the Data-side (D-side) controller relative to the Radar-side (R-side) controller is a potential approach to mitigating workload for the traffic management specialist, as the D-side controller would have similar ability to perform separation management functions in what today might be considered the "trajectory management" timeframe. This analysis did not distinguish between the D-side and R-side controllers since in many cases the R-side controller works unassisted.

  16. Closed Loop Requirements and Analysis Management

    NASA Technical Reports Server (NTRS)

    Lamoreaux, Michael; Verhoef, Brett

    2015-01-01

    Effective systems engineering involves the use of analysis in the derivation of requirements and verification of designs against those requirements. The initial development of requirements often depends on analysis for the technical definition of specific aspects of a product. Following the allocation of system-level requirements to a product's components, the closure of those requirements often involves analytical approaches to verify that the requirement criteria have been satisfied. Meanwhile, changes that occur in between these two processes need to be managed in order to achieve a closed-loop requirement derivation/verification process. Herein are presented concepts for employing emerging Team center capabilities to jointly manage requirements and analysis data such that analytical techniques are utilized to effectively derive and allocate requirements, analyses are consulted and updated during the change evaluation processes, and analyses are leveraged during the design verification process. Recommendations on concept validation case studies are also discussed.

  17. If You're a Rawlsian, How Come You're So Close to Utilitarianism and Intuitionism? A Critique of Daniels's Accountability for Reasonableness.

    PubMed

    Badano, Gabriele

    2018-03-01

    Norman Daniels's theory of 'accountability for reasonableness' is an influential conception of fairness in healthcare resource allocation. Although it is widely thought that this theory provides a consistent extension of John Rawls's general conception of justice, this paper shows that accountability for reasonableness has important points of contact with both utilitarianism and intuitionism, the main targets of Rawls's argument. My aim is to demonstrate that its overlap with utilitarianism and intuitionism leaves accountability for reasonableness open to damaging critiques. The important role that utilitarian-like cost-effectiveness calculations are allowed to play in resource allocation processes disregards the separateness of persons and is seriously unfair towards individuals whose interests are sacrificed for the sake of groups. Furthermore, the function played by intuitions in settling frequent value conflicts opens the door for sheer custom and vested interests to steer decision-making.

  18. Barriers to implementation of workplace health interventions: an economic perspective.

    PubMed

    Cherniack, Martin; Lahiri, Supriya

    2010-09-01

    To identify insurance related, structural, and workplace cultural barriers to the implementation of effective preventive and upstream clinical interventions in the working age adult population. Analysis of avoided costs from perspective of health economics theory and from empiric observations from large studies; presentation of data from our own cost-plus model on integrating health promotion and ergonomics. We identify key avoided costs issues as a misalignment of interests between employers, insurers, service institutions, and government. Conceptual limitations of neoclassical economics are attributable to work culture and supply-driven nature of health care. Effective valuation of avoided costs is a necessary condition for redirecting allocations and incentives. Key content for valuation models is discussed.

  19. Critical threshold behavior for steady-state internal transport barriers in burning plasmas.

    PubMed

    García, J; Giruzzi, G; Artaud, J F; Basiuk, V; Decker, J; Imbeaux, F; Peysson, Y; Schneider, M

    2008-06-27

    Burning tokamak plasmas with internal transport barriers are investigated by means of integrated modeling simulations. The barrier sustainment in steady state, differently from the barrier formation process, is found to be characterized by a critical behavior, and the critical number of the phase transition is determined. Beyond a power threshold, alignment of self-generated and noninductively driven currents occurs and steady state becomes possible. This concept is applied to simulate a steady-state scenario within the specifications of the International Thermonuclear Experimental Reactor.

  20. Perceived barriers to implementing screening and brief intervention for alcohol consumption by adolescents in hospital emergency department in Spain.

    PubMed

    Falcón, María; Navarro-Zaragoza, Javier; García-Rodríguez, Rosa María; Nova-López, Daniel; González-Navarro, María Dulce; Mercadal, María; García-Algar, Oscar; Luna Ruiz-Cabello, Aurelio

    2017-07-14

    Screening for alcohol consumption in adolescents is widely justified in the health care field because of the particular vulnerability of this population, which starts drinking alcohol at a very early age and frequently consumes high levels of the same. Hospital emergency departments (ED) could be a good venue to manage early detection and carry out brief intervention (BI) programmes. The aim of this study was to identify perceived barriers for medical staff of three hospitals in Spain to successfully implement a protocol for alcohol detection and BI for minors in the ED. Exploratory qualitative analysis using focus groups with semi-structured, flexible and open-ended questions to explore beliefs, attitudes, and barriers perceived by professionals to screening alcohol consumption and implementing BI in adolescents attended at the ED. The main perceived barriers by health professionals were lack of time, work overload, mistrust, lack of validated and simple screening tools, lack of training/awareness and legal concerns about informed consent and confidentiality. Barriers to screening and intervention in ED are similar to those described previously. It is necessary to improve organization of time allocated for medical consultations, avoid limiting ED resources, motivate staff and provide appropriate training.

  1. On long-only information-based portfolio diversification framework

    NASA Astrophysics Data System (ADS)

    Santos, Raphael A.; Takada, Hellinton H.

    2014-12-01

    Using the concepts from information theory, it is possible to improve the traditional frameworks for long-only asset allocation. In modern portfolio theory, the investor has two basic procedures: the choice of a portfolio that maximizes its risk-adjusted excess return or the mixed allocation between the maximum Sharpe portfolio and the risk-free asset. In the literature, the first procedure was already addressed using information theory. One contribution of this paper is the consideration of the second procedure in the information theory context. The performance of these approaches was compared with three traditional asset allocation methodologies: the Markowitz's mean-variance, the resampled mean-variance and the equally weighted portfolio. Using simulated and real data, the information theory-based methodologies were verified to be more robust when dealing with the estimation errors.

  2. Concept for individualized patient allocation: ReCompare—remote comparison of particle and photon treatment plans

    PubMed Central

    2014-01-01

    Background Identifying those patients who have a higher chance to be cured with fewer side effects by particle beam therapy than by state-of-the-art photon therapy is essential to guarantee a fair and sufficient access to specialized radiotherapy. The individualized identification requires initiatives by particle as well as non-particle radiotherapy centers to form networks, to establish procedures for the decision process, and to implement means for the remote exchange of relevant patient information. In this work, we want to contribute a practical concept that addresses these requirements. Methods We proposed a concept for individualized patient allocation to photon or particle beam therapy at a non-particle radiotherapy institution that bases on remote treatment plan comparison. We translated this concept into the web-based software tool ReCompare (REmote COMparison of PARticlE and photon treatment plans). Results We substantiated the feasibility of the proposed concept by demonstrating remote exchange of treatment plans between radiotherapy institutions and the direct comparison of photon and particle treatment plans in photon treatment planning systems. ReCompare worked with several tested standard treatment planning systems, ensured patient data protection, and integrated in the clinical workflow. Conclusions Our concept supports non-particle radiotherapy institutions with the patient-specific treatment decision on the optimal irradiation modality by providing expertise from a particle therapy center. The software tool ReCompare may help to improve and standardize this personalized treatment decision. It will be available from our website when proton therapy is operational at our facility. PMID:24548333

  3. Weight, Mass, and Gravity: Threshold Concepts in Learning Science

    ERIC Educational Resources Information Center

    Bar, Varda; Brosh, Yaffa; Sneider, Cary

    2016-01-01

    Threshold concepts are essential ideas about the natural world that present either a barrier or a gateway to a deep understanding of science. Weight, mass, and gravity are threshold concepts that underpin students' abilities to understand important ideas in all fields of science, embodied in the performance expectations in the Next Generation…

  4. Spectrum and power allocation in cognitive multi-beam satellite communications with flexible satellite payloads

    NASA Astrophysics Data System (ADS)

    Liu, Zhihui; Wang, Haitao; Dong, Tao; Yin, Jie; Zhang, Tingting; Guo, Hui; Li, Dequan

    2018-02-01

    In this paper, the cognitive multi-beam satellite system, i.e., two satellite networks coexist through underlay spectrum sharing, is studied, and the power and spectrum allocation method is employed for interference control and throughput maximization. Specifically, the multi-beam satellite with flexible payload reuses the authorized spectrum of the primary satellite, adjusting its transmission band as well as power for each beam to limit its interference on the primary satellite below the prescribed threshold and maximize its own achievable rate. This power and spectrum allocation problem is formulated as a mixed nonconvex programming. For effective solving, we first introduce the concept of signal to leakage plus noise ratio (SLNR) to decouple multiple transmit power variables in the both objective and constraint, and then propose a heuristic algorithm to assign spectrum sub-bands. After that, a stepwise plus slice-wise algorithm is proposed to implement the discrete power allocation. Finally, simulation results show that adopting cognitive technology can improve spectrum efficiency of the satellite communication.

  5. The NGST Science Instrument Procurement Plan

    NASA Astrophysics Data System (ADS)

    NGST Project Office Team

    1999-05-01

    The NGST will carry approximately 3 science instruments (SI) that together enable the wide field imaging and spectroscopic capability needed to perform the Design Reference Mission (http://www.ngst.nasa.gov/science/drm.html). The NGST telescope will permit these instruments to achieve Zodiacal light limited sensitivity over a wavelength range of 0.6 - 10+ microns. During April 2000, responsibility to provide these instruments will be allocated among the NGST partner agencies: NASA, ESA, and CSA. Instruments allocated to NASA will be solicited via a NASA Announcement of Opportunity (AO) during June 2001. This AO will be open to university, government, and industry scientists. At the present time, 11 science instrument concept studies are being conducted by US, European, and Canadian teams. Final results from these 1 year studies will be presented at the NGST Science and Technology Exposition at Woods Hole MA during September 1999 (http://ngst.gsfc.nasa.gov/science/meetings/WHannouncement.html). It is not necessary to have participated in these pre-Phase A activities in order to answer the up coming instrument technologies NRA or the flight instrument AO. In this poster, we present the process by which SI concepts will be allocated among NASA, ESA, and CSA prior to the AO solicitation as well as top level time lines for instrument acquisition and development.

  6. Artificial Intelligence Based Control Power Optimization on Tailless Aircraft. [ARMD Seedling Fund Phase I

    NASA Technical Reports Server (NTRS)

    Gern, Frank; Vicroy, Dan D.; Mulani, Sameer B.; Chhabra, Rupanshi; Kapania, Rakesh K.; Schetz, Joseph A.; Brown, Derrell; Princen, Norman H.

    2014-01-01

    Traditional methods of control allocation optimization have shown difficulties in exploiting the full potential of controlling large arrays of control devices on innovative air vehicles. Artificial neutral networks are inspired by biological nervous systems and neurocomputing has successfully been applied to a variety of complex optimization problems. This project investigates the potential of applying neurocomputing to the control allocation optimization problem of Hybrid Wing Body (HWB) aircraft concepts to minimize control power, hinge moments, and actuator forces, while keeping system weights within acceptable limits. The main objective of this project is to develop a proof-of-concept process suitable to demonstrate the potential of using neurocomputing for optimizing actuation power for aircraft featuring multiple independently actuated control surfaces. A Nastran aeroservoelastic finite element model is used to generate a learning database of hinge moment and actuation power characteristics for an array of flight conditions and control surface deflections. An artificial neural network incorporating a genetic algorithm then uses this training data to perform control allocation optimization for the investigated aircraft configuration. The phase I project showed that optimization results for the sum of required hinge moments are improved by more than 12% over the best Nastran solution by using the neural network optimization process.

  7. Decision-making in crisis: Applying a healthcare triage methodology to business continuity management.

    PubMed

    Moore, Bethany; Bone, Eric A

    2017-01-01

    The concept of triage in healthcare has been around for centuries and continues to be applied today so that scarce resources are allocated according to need. A business impact analysis (BIA) is a form of triage in that it identifies which processes are most critical, which to address first and how to allocate limited resources. On its own, however, the BIA provides only a roadmap of the impacts and interdependencies of an event. When disaster strikes, organisational decision-makers often face difficult decisions with regard to allocating limited resources between multiple 'mission-critical' functions. Applying the concept of triage to business continuity provides those decision-makers navigating a rapidly evolving and unpredictable event with a path that protects the fundamental priorities of the organisation. A business triage methodology aids decision-makers in times of crisis by providing a simplified framework for decision-making based on objective, evidence-based criteria, which is universally accepted and understood. When disaster strikes, the survival of the organisation depends on critical decision-making and quick actions to stabilise the incident. This paper argues that organisations need to supplement BIA processes with a decision-making triage methodology that can be quickly applied during the chaos of an actual event.

  8. Organ Transplantation in the Face of Donor Shortage - Ethical Implications with a Focus on Liver Allocation

    PubMed Central

    Lauerer, Michael; Kaiser, Katharina; Nagel, Eckhard

    2016-01-01

    Background Transplantation medicine is associated with several ethical issues related to the lack of organs. Major questions concern the regulations for giving permission for organ removal, informing the public about organ donation, setting of organ allocation priorities, waiting list access, and strategies to counteract scarcity. Methods This contribution is based on analyses of legal regulations, guidelines of self-regulatory bodies, administrative data, and literature from medical, normative, and empiric disciplines. It addresses the above-mentioned issues descriptively with a focus on Germany and liver transplantation. Results The basic principle of beneficence justifies a shift from voluntariness towards an obligation to document one's decision regarding organ donation. Organ allocation is obviously tangent to fundamental values and concepts of justice. At that, there is no consistent agreement on whether to prioritize the sickest patient or to maximize the overall health benefit. Restrictions relating to waiting list access are the subject of controversies. The reasons for denial of access are largely related to high demands on the prospect of success. Strategies to counteract organ scarcity partly conflict with the respect for autonomy, non-maleficence, beneficence, or justice. Conclusion We propose to focus on recent most promising strategies to counteract scarcity in the short-term: demanding a documented decision on organ donation and an orientation towards the Spanish model of organization. Concepts for waiting list access should constantly be reviewed considering all medical evidence and must not be based on moralism. Moreover, we suggest to consider public preferences for organ allocation and strengthen the confidence in transplantation medicine. PMID:27722165

  9. Organ Transplantation in the Face of Donor Shortage - Ethical Implications with a Focus on Liver Allocation.

    PubMed

    Lauerer, Michael; Kaiser, Katharina; Nagel, Eckhard

    2016-08-01

    Transplantation medicine is associated with several ethical issues related to the lack of organs. Major questions concern the regulations for giving permission for organ removal, informing the public about organ donation, setting of organ allocation priorities, waiting list access, and strategies to counteract scarcity. This contribution is based on analyses of legal regulations, guidelines of self-regulatory bodies, administrative data, and literature from medical, normative, and empiric disciplines. It addresses the above-mentioned issues descriptively with a focus on Germany and liver transplantation. The basic principle of beneficence justifies a shift from voluntariness towards an obligation to document one's decision regarding organ donation. Organ allocation is obviously tangent to fundamental values and concepts of justice. At that, there is no consistent agreement on whether to prioritize the sickest patient or to maximize the overall health benefit. Restrictions relating to waiting list access are the subject of controversies. The reasons for denial of access are largely related to high demands on the prospect of success. Strategies to counteract organ scarcity partly conflict with the respect for autonomy, non-maleficence, beneficence, or justice. We propose to focus on recent most promising strategies to counteract scarcity in the short-term: demanding a documented decision on organ donation and an orientation towards the Spanish model of organization. Concepts for waiting list access should constantly be reviewed considering all medical evidence and must not be based on moralism. Moreover, we suggest to consider public preferences for organ allocation and strengthen the confidence in transplantation medicine.

  10. Simple versus composite indicators of socioeconomic status in resource allocation formulae: the case of the district resource allocation formula in Malawi

    PubMed Central

    2010-01-01

    Background The district resource allocation formula in Malawi was recently reviewed to include stunting as a proxy measure of socioeconomic status. In many countries where the concept of need has been incorporated in resource allocation, composite indicators of socioeconomic status have been used. In the Malawi case, it is important to ascertain whether there are differences between using single variable or composite indicators of socioeconomic status in allocations made to districts, holding all other factors in the resource allocation formula constant. Methods Principal components analysis was used to calculate asset indices for all districts from variables that capture living standards using data from the Malawi Multiple Indicator Cluster Survey 2006. These were normalized and used to weight district populations. District proportions of national population weighted by both the simple and composite indicators were then calculated for all districts and compared. District allocations were also calculated using the two approaches and compared. Results The two types of indicators are highly correlated, with a spearman rank correlation coefficient of 0.97 at the 1% level of significance. For 21 out of the 26 districts included in the study, proportions of national population weighted by the simple indicator are higher by an average of 0.6 percentage points. For the remaining 5 districts, district proportions of national population weighted by the composite indicator are higher by an average of 2 percentage points. Though the average percentage point differences are low and the actual allocations using both approaches highly correlated (ρ of 0.96), differences in actual allocations exceed 10% for 8 districts and have an average of 4.2% for the remaining 17. For 21 districts allocations based on the single variable indicator are higher. Conclusions Variations in district allocations made using either the simple or composite indicators of socioeconomic status are not statistically different to recommend one over the other. However, the single variable indicator is favourable for its ease of computation. PMID:20053274

  11. Asynchronous Communication of TLNS3DMB Boundary Exchange

    NASA Technical Reports Server (NTRS)

    Hammond, Dana P.

    1997-01-01

    This paper describes the recognition of implicit serialization due to coarse-grain, synchronous communication and demonstrates the conversion to asynchronous communication for the exchange of boundary condition information in the Thin-Layer Navier Stokes 3-Dimensional Multi Block (TLNS3DMB) code. The implementation details of using asynchronous communication is provided including buffer allocation, message identification, and barrier control. The IBM SP2 was used for the tests presented.

  12. Health economics--concepts and conceptual problems.

    PubMed

    Satpathy, S K; Bansal, R D

    1982-01-01

    Awareness of the economic manifestation of health and diseases and the limited resources allocated to health care services has brought to the focus a new discipline - health economics. Cost accounting, cost benefit, cost effectiveness methods etc. are increasingly becoming an integral part of the health management and evaluation of health programmes. Various concepts and problems relating to health economics are discussed in the present paper. More efforts should be made to conduct health economic studies in hospitals and health centres by which the process of standardisation of the concepts, would be easier. Health economics should also find its due place in the medical curriculum.

  13. Economic evaluations of health technologies in Dutch healthcare decision-making: a qualitative study of the current and potential use, barriers, and facilitators.

    PubMed

    Roseboom, Kitty J; van Dongen, Johanna M; Tompa, Emile; van Tulder, Maurits W; Bosmans, Judith E

    2017-01-26

    The use of economic evaluations in healthcare decision-making can potentially help decision-makers in allocating scarce resources as efficiently as possible. Over a decade ago, the use of such studies was found to be limited in Dutch healthcare decision-making, but their current use is unknown. Therefore, this study aimed to provide insight into the current and potential use of economic evaluations in Dutch healthcare decision-making and to identify barriers and facilitators to the use of such studies. Interviews containing semi-structured and structured questions were conducted among Dutch healthcare decision-makers. Participants were purposefully selected and special efforts were made to include decision-makers working at the macro- (national), meso- (local/regional), and micro-level (patient setting). During the interviews, a topic list was used that was based on the research questions and a literature search, and was developed in consultation with the Dutch National Healthcare Institute. Responses to the semi-structured questions were analyzed using a constant comparative approach. As for the structured questions, participants' definitions of various economic evaluation concepts were scored as either being "correct" or "incorrect" by two researchers, and summary statistics were prepared. Sixteen healthcare decision-makers were interviewed and two health economists. Decision-makers' knowledge of economic evaluations was only modest, and their current use appeared to be limited. Nonetheless, decision-makers recognized the importance of economic evaluations and saw several opportunities for extending their use at the macro- and meso-level, but not at the micro-level. The disparity between the limited use and recognition of the importance of economic evaluations is likely due to the many barriers decision-makers experience preventing their use (e.g. lack of resources, lack of formal willingness-to-pay threshold). Possible facilitators for extending the use of economic evaluations include, amongst others, educating decision-makers and the general population about economic evaluations and presenting economic evaluation results in a clearer and more understandable way. This study demonstrated that the current use and impact of economic evaluations in Dutch healthcare decision-making is limited at best. Therefore, strategies are needed to overcome the barriers that currently prevent economic evaluations from being used extensively.

  14. Identifying Atomic Structure as a Threshold Concept: Student Mental Models and Troublesomeness

    ERIC Educational Resources Information Center

    Park, Eun Jung; Light, Gregory

    2009-01-01

    Atomic theory or the nature of matter is a principal concept in science and science education. This has, however, been complicated by the difficulty students have in learning the concept and the subsequent construction of many alternative models. To understand better the conceptual barriers to learning atomic structure, this study explores the…

  15. Seeing beyond borders: a game theoretic approach to anticipate the effect of satellite monitoring data on transboundary freshwater allocation.

    NASA Astrophysics Data System (ADS)

    Muller, M. F.; Gorelick, S.; Muller-Itten, M. C.

    2015-12-01

    The allocation of transboundary freshwater resources is a ubiquitous challenge with direct repercussions on the political stability of the concerned region. Under the right conditions, the need to share scarce water resources can act as a catalyst for dialogue between otherwise hostile neighbors. Yet the strategic reluctance of the involved parties to share water diversion and use data remains a major barrier that raises the probability of conflict. In that context, high-quality satellite data are progressively available to monitor water resources beyond political boundaries. These datasets have an increasing role to play in the allocation of shared waters. We develop a game theoretical framework to predict their effect on transboundary water negotiations. We consider repetitions of a game between two countries that have a water allocation agreement for transboundary river flow. The upstream country can observe the available flow in any given year and decide whether or not to provide her neighbor with the agreed upon river discharge. The downstream country cannot observe the initially available flow. He only observes the water allocated provided by his upstream neighbor and can take actions to impose a sanction on her if he can confidently determine that the agreement has been breached. In that context, satellite monitoring data will affect the informational advantage of the upstream country and increase her probability of either abiding by the agreement or being caught when breaching it. We find that the informed equilibrium will produce a lower probability of conflict, but changes in both players' positions regarding equitable allocation may destabilize the existing agreement in the short term.

  16. Analytical method of waste allocation in waste management systems: Concept, method and case study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bergeron, Francis C., E-mail: francis.b.c@videotron.ca

    Waste is not a rejected item to dispose anymore but increasingly a secondary resource to exploit, influencing waste allocation among treatment operations in a waste management (WM) system. The aim of this methodological paper is to present a new method for the assessment of the WM system, the “analytical method of the waste allocation process” (AMWAP), based on the concept of the “waste allocation process” defined as the aggregation of all processes of apportioning waste among alternative waste treatment operations inside or outside the spatial borders of a WM system. AMWAP contains a conceptual framework and an analytical approach. Themore » conceptual framework includes, firstly, a descriptive model that focuses on the description and classification of the WM system. It includes, secondly, an explanatory model that serves to explain and to predict the operation of the WM system. The analytical approach consists of a step-by-step analysis for the empirical implementation of the conceptual framework. With its multiple purposes, AMWAP provides an innovative and objective modular method to analyse a WM system which may be integrated in the framework of impact assessment methods and environmental systems analysis tools. Its originality comes from the interdisciplinary analysis of the WAP and to develop the conceptual framework. AMWAP is applied in the framework of an illustrative case study on the household WM system of Geneva (Switzerland). It demonstrates that this method provides an in-depth and contextual knowledge of WM. - Highlights: • The study presents a new analytical method based on the waste allocation process. • The method provides an in-depth and contextual knowledge of the waste management system. • The paper provides a reproducible procedure for professionals, experts and academics. • It may be integrated into impact assessment or environmental system analysis tools. • An illustrative case study is provided based on household waste management in Geneva.« less

  17. Contextual and interdependent causes of climate change adaptation barriers: Insights from water management institutions in Himachal Pradesh, India.

    PubMed

    Azhoni, Adani; Holman, Ian; Jude, Simon

    2017-01-15

    Research on adaptation barriers is increasing as the need for climate change adaptation becomes evident. However, empirical studies regarding the emergence, causes and sustenance of adaptation barriers remain limited. This research identifies key contextual causes of adaptation barriers in water institutions in the mountainous Himalayan state of Himachal Pradesh in northern India. Semi-structured interviews were carried out with representatives from twenty-six key governmental, non-governmental, academic and research institutions in the State with responsibilities spanning domestic water supply, irrigation and hydropower generation, environmental monitoring and research. It identified low knowledge capacity and resources, policy implementation gaps, normative attitudes, and unavailability and inaccessibility of data and information compounded with weak interinstitutional networks as key adaptation barriers. Although these barriers are similar to those reported elsewhere, they have important locally-contextual root causes. For instance, inadequate resources result from fragmented resources allocation due to competing developmental priorities and the desire of the political leadership to please diverse electors, rather than climate scepticism. The identified individual barriers are found to be highly inter-dependent and closely intertwined which enables the identification of leverage points for interventions to maximise barrier removal. For instance, breaking down key barriers hindering accessibility to data and information, which are shaped by systemic bureaucracies and cultural attitudes, will involve attitudinal change through sensitisation to the importance of accurate and accessible data and information and the building trust between different actors, in addition to institutional structural changes through legislation and inter-institutional agreements. Approaching barriers as a system of contextually interconnected cultural, systemic, geographical and political underlying factors enriches the understanding of adaptation enablers, thereby contributing to achieving a better adapted society. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  18. Disease management in Canada: surmounting barriers to adoption.

    PubMed

    Gallant, Christopher R; MacKinnon, Neil J; Sprague, Denise A

    2007-01-01

    Disease Management (DM) programs are used to optimize economic outcomes and improve patient outcomes. Despite this, relative to the United States, Canadian health care organizations have been slow to adopt them. The objective of this article is to examine the concept of DM programs, the existing evidence to support their use and the barriers to their adoption in Canada. Several solutions aimed at overcoming the barriers to DM in Canada are proposed.

  19. New Media Resistance: Barriers to Implementation of Computer Video Games in the Classroom

    ERIC Educational Resources Information Center

    Rice, John W.

    2007-01-01

    Computer video games are an emerging instructional medium offering strong degrees of cognitive efficiencies for experiential learning, team building, and greater understanding of abstract concepts. As with other new media adopted for use by instructional technologists for pedagogical purposes, barriers to classroom implementation have manifested…

  20. [Complexity of care: meanings and interpretation].

    PubMed

    Cologna, Marina; Zanolli, Daniela; Saiani, Luisa

    2010-01-01

    Although the concept of complexity of care is widely used and discussed, its meaning is blurred and its characteristics are not well defined. To identify the words used to define the concept of complexity in the literature and its meaning. A literature search was performed on the following databases: Pubmed, Medline, Ebsco, Cinahl and Cochrane. No temporal limits were set; publications written in English and Italian were included. Several terms are used to define the concept of complexity, often interchangeably notwithstanding their different meaning. Three main concepts were identified: nursing intensity that includes the concepts of dependency, severity and complexity of patients care; nursing workload that comprises the concept of nursing intensity and all the activities not patient-related; and the patient acuity that includes the severity of illness and the caring intensity. A common definition is needed to be able to use the concept of complexity of care to allocate nursing resources.

  1. Applying Intermediate Microeconomics to Terrorism

    ERIC Educational Resources Information Center

    Anderton, Charles H.; Carter, John R.

    2006-01-01

    The authors show how microeconomic concepts and principles are applicable to the study of terrorism. The utility maximization model provides insights into both terrorist resource allocation choices and government counterterrorism efforts, and basic game theory helps characterize the strategic interdependencies among terrorists and governments.…

  2. Productivity--The Concept and its Uses.

    ERIC Educational Resources Information Center

    Whitmarsh, David

    1982-01-01

    Defines various aspects of productivity and indicates appropriate ways of measuring them. The author explains how productivity ratios can be used to evaluate both the technical and allocative efficiency of economic systems. The use of productivity analysis in growth accounting is also examined. (Author/RM)

  3. Financial obligations and economic barriers to antiretroviral therapy experienced by HIV positive women who participated in a job-creation programme in northern Uganda

    PubMed Central

    Dovel, Kathryn; Thompson, Kallie

    2016-01-01

    Economic costs are commonly cited as barriers to women’s use of antiretroviral therapy (ART) in sub-Saharan Africa; however, little is known about how changes in women’s income influence economic barriers to care. We analysed in-depth interviews with 17 HIV positive women who participated in a job-creation programme in northern Uganda and two key informant interviews with programme staff to examine lingering economic barriers to care experienced after programme enrolment. We found that participants continued to experience economic barriers even after receiving steady a income and improving their economic status. Two themes emerged: first, limited resources in health facilities (e.g., drug and staff shortages) led participants to view ART utilisation as a primarily economic endeavour where clients made informal payments for prompter services or sought treatment in private facilities where ART was readily available; second, increased economic status also increased expectations of economic reciprocity among participants’ social networks. Financial obligations often manifested in the form of caring for additional dependents, limiting the resources women could allocate toward their HIV treatment. When paired with limited resources in health facilities, increased financial obligations perpetuated the economic barriers to care experienced by participants. Job-creation programmes should consider how health institutions interact with participants’ financial obligations to influence women’s access to HIV services. PMID:26652011

  4. Financial obligations and economic barriers to antiretroviral therapy experienced by HIV-positive women who participated in a job-creation programme in northern Uganda.

    PubMed

    Dovel, Kathryn; Thomson, Kallie

    2016-01-01

    Economic costs are commonly cited as barriers to women's use of antiretroviral therapy (ART) in sub-Saharan Africa; however, little is known about how changes in women's income influence economic barriers to care. We analysed in-depth interviews with 17 HIV-positive women who participated in a job-creation programme in northern Uganda and two key informant interviews with programme staff to examine lingering economic barriers to care experienced after programme enrollment. We found that participants continued to experience economic barriers even after receiving a steady income and improving their economic status. Two themes emerged: first, limited resources in health facilities (e.g. drug and staff shortages) led participants to view ART utilisation as a primarily economic endeavour where clients made informal payments for prompter service or sought treatment in private facilities where ART was readily available; second, increased economic status among participants increased expectations of economic reciprocity among participants' social networks. Financial obligations often manifested themselves in the form of caring for additional dependents, limiting the resources women could allocate toward their HIV treatment. When paired with limited resources in health facilities, increased financial obligations perpetuated the economic barriers experienced by participants. Job-creation programmes should consider how health institutions interact with participants' financial obligations to influence women's access to HIV services.

  5. Evidence-based surgery: barriers, solutions, and the role of evidence synthesis.

    PubMed

    Garas, George; Ibrahim, Amel; Ashrafian, Hutan; Ahmed, Kamran; Patel, Vanash; Okabayashi, Koji; Skapinakis, Petros; Darzi, Ara; Athanasiou, Thanos

    2012-08-01

    Surgery is a rapidly evolving field, making the rigorous testing of emerging innovations vital. However, most surgical research fails to employ randomized controlled trials (RCTs) and has particularly been based on low-quality study designs. Subsequently, the analysis of data through meta-analysis and evidence synthesis is particularly difficult. Through a systematic review of the literature, this article explores the barriers to achieving a strong evidence base in surgery and offers potential solutions to overcome the barriers. Many barriers exist to evidence-based surgical research. They include enabling factors, such as funding, time, infrastructure, patient preference, ethical issues, and additionally barriers associated with specific attributes related to researchers, methodologies, or interventions. Novel evidence synthesis techniques in surgery are discussed, including graphics synthesis, treatment networks, and network meta-analyses that help overcome many of the limitations associated with existing techniques. They offer the opportunity to assess gaps and quantitatively present inconsistencies within the existing evidence of RCTs. Poorly or inadequately performed RCTs and meta-analyses can give rise to incorrect results and thus fail to inform clinical practice or revise policy. The above barriers can be overcome by providing academic leadership and good organizational support to ensure that adequate personnel, resources, and funding are allocated to the researcher. Training in research methodology and data interpretation can ensure that trials are conducted correctly and evidence is adequately synthesized and disseminated. The ultimate goal of overcoming the barriers to evidence-based surgery includes the improved quality of patient care in addition to enhanced patient outcomes.

  6. Toward an Application Guide for Safety Integrity Level Allocation in Railway Systems.

    PubMed

    Ouedraogo, Kiswendsida Abel; Beugin, Julie; El-Koursi, El-Miloudi; Clarhaut, Joffrey; Renaux, Dominique; Lisiecki, Frederic

    2018-02-02

    The work in the article presents the development of an application guide based on feedback and comments stemming from various railway actors on their practices of SIL allocation to railway safety-related functions. The initial generic methodology for SIL allocation has been updated to be applied to railway rolling stock safety-related functions in order to solve the SIL concept application issues. Various actors dealing with railway SIL allocation problems are the intended target of the methodology; its principles will be summarized in this article with a focus on modifications and precisions made in order to establish a practical guide for railway safety authorities. The methodology is based on the flowchart formalism used in CSM (common safety method) European regulation. It starts with the use of quantitative safety requirements, particularly tolerable hazard rates (THR). THR apportioning rules are applied. On the one hand, the rules are related to classical logical combinations of safety-related functions preventing hazard occurrence. On the other hand, to take into account technical conditions (last safety weak link, functional dependencies, technological complexity, etc.), specific rules implicitly used in existing practices are defined for readjusting some THR values. SIL allocation process based on apportioned and validated THR values is finally illustrated through the example of "emergency brake" subsystems. Some specific SIL allocation rules are also defined and illustrated. © 2018 Society for Risk Analysis.

  7. What Happens to the Food We Eat? Children's Conceptions of the Structure and Function of the Digestive System.

    ERIC Educational Resources Information Center

    Teixeira, Francimar Martins

    2000-01-01

    Describes children's conceptions of the structure and function of the human digestive system based on an investigation carried out with children aged 4-10 (n=45). Finds that children possess biological knowledge as an independent knowledge domain from the age of four. Discusses acquisition of and barriers to scientific concepts related to human…

  8. Facilitators and barriers of adopting healthy lifestyle in rural China: a qualitative analysis through social capital perspectives.

    PubMed

    Zhang, Yan; Ma, Defu; Cui, Renzhe; Haregot Hilawe, Esayas; Chiang, Chifa; Hirakawa, Yoshihisa; Hu, Yonghua; Wang, Peiyu; Iso, Hiroyasu; Aoyama, Atsuko

    2016-05-01

    Non-communicable diseases (NCDs) are the major public health concerns in China. However, little has been known yet about the background social factors that influence lifestyles as possible NCD risk factors. This qualitative study aimed to explore facilitators and barriers of adopting healthy lifestyles among residents in a rural community of China. Three age-stratified focus group discussions (FGDs) were conducted in Fangshan district of Beijing in 2013. A FGD guide was designed to elicit the participants' perception and experience regarding their lifestyles. The audio-records were transcribed, and data were qualitatively analyzed through thematic approach. Through social capital framework with bonding, bridging, and linking classifications, we identified the following facilitators and barriers to adopt healthy lifestyles. (1) Facilitators: mutual support from family/friends and motivation to participate in regular exercises (bonding); cooperative relationships with community health workers (bridging); and nationwide high level of healthy lifestyle awareness (linking). (2) Barriers: negative influence from family/friends, insufficient support from family/friends, peer pressure and tolerance towards unhealthy lifestyles (bonding); insufficient support from health professionals (bridging); and inequity in allocation of public resources (linking). This study revealed that bonding, bridging and linking social capital would work as facilitators and barriers to adopt healthy lifestyles among rural residents in China.

  9. Capacity planning for waste management systems: an interval fuzzy robust dynamic programming approach.

    PubMed

    Nie, Xianghui; Huang, Guo H; Li, Yongping

    2009-11-01

    This study integrates the concepts of interval numbers and fuzzy sets into optimization analysis by dynamic programming as a means of accounting for system uncertainty. The developed interval fuzzy robust dynamic programming (IFRDP) model improves upon previous interval dynamic programming methods. It allows highly uncertain information to be effectively communicated into the optimization process through introducing the concept of fuzzy boundary interval and providing an interval-parameter fuzzy robust programming method for an embedded linear programming problem. Consequently, robustness of the optimization process and solution can be enhanced. The modeling approach is applied to a hypothetical problem for the planning of waste-flow allocation and treatment/disposal facility expansion within a municipal solid waste (MSW) management system. Interval solutions for capacity expansion of waste management facilities and relevant waste-flow allocation are generated and interpreted to provide useful decision alternatives. The results indicate that robust and useful solutions can be obtained, and the proposed IFRDP approach is applicable to practical problems that are associated with highly complex and uncertain information.

  10. Are pricing and reimbursement decision-making criteria aligned with public preferences regarding allocation principles in the Polish healthcare sector?

    PubMed

    Kolasa, Katarzyna

    2014-10-01

    Given growing interest in multicriteria decision making and multiple cost-effectiveness thresholds' approach, it was decided to investigate its usefulness in Poland. The pricing and reimbursement (P&R) regulations were reviewed and a cross-sectional survey was conducted amongst nurses. The study investigated whether P&R rules are aligned with the preferences of healthcare professional towards the concept of equity. The references to aversion to inequalities in health and capacity to benefit were recognized as the most and least important principle respectively by the group of nurses. Different weightings of health gain dependent on disease severity were accepted by half of the study's population. In the review of legal acts, references to capacity to benefit were frequently found. The opposite was registered for other concepts of equity. There is room for further improvement with respect to the alignment between the Polish P&R decision making criteria and public preferences regarding allocation principles.

  11. Utilizing a TDRS satellite for direct broadcast satellite-radio propagation experiments and demonstrations

    NASA Technical Reports Server (NTRS)

    Hollansworth, James E.

    1993-01-01

    The NASA/VOA Direct Broadcast Satellite-Radio (DBS-R) Program will be using a NASA Tracking Data Relay Satellite (TDRS) satellite at 62 deg. West longitude to conduct live satellite S-band propagation experiments and demonstrations of satellite sound broadcasting over the next two years (1993-1994). The NASA/VOA DBS-R program has applied intensive effort to garner domestic and international support for the DBS-R concept. An S-band DBS-R allocation was achieved for Region 2 at WARC-92 held in Spain. With this allocation, the DBS-R program now needs to conduct S-band propagation experiments and systems demonstrations that will assist in the development of planning approaches for the use of Broadcast Satellite Service (Sound) frequency bands prior to the planning conference called for by WARC-92. These activities will also support receiver concept development applied to qualities ranging from AM to Monophonic FM, Stereophonic FM, Monophonic CD, and Stereophonic CD quality.

  12. Resource Economics

    NASA Astrophysics Data System (ADS)

    Conrad, Jon M.

    2000-01-01

    Resource Economics is a text for students with a background in calculus, intermediate microeconomics, and a familiarity with the spreadsheet software Excel. The book covers basic concepts, shows how to set up spreadsheets to solve dynamic allocation problems, and presents economic models for fisheries, forestry, nonrenewable resources, stock pollutants, option value, and sustainable development. Within the text, numerical examples are posed and solved using Excel's Solver. These problems help make concepts operational, develop economic intuition, and serve as a bridge to the study of real-world problems of resource management. Through these examples and additional exercises at the end of Chapters 1 to 8, students can make dynamic models operational, develop their economic intuition, and learn how to set up spreadsheets for the simulation of optimization of resource and environmental systems. Book is unique in its use of spreadsheet software (Excel) to solve dynamic allocation problems Conrad is co-author of a previous book for the Press on the subject for graduate students Approach is extremely student-friendly; gives students the tools to apply research results to actual environmental issues

  13. Networked Rectenna Array for Smart Material Actuators

    NASA Technical Reports Server (NTRS)

    Choi, Sang H.; Golembiewski, Walter T.; Song, Kyo D.

    2000-01-01

    The concept of microwave-driven smart material actuators is envisioned as the best option to alleviate the complexity associated with hard-wired control circuitry. Networked rectenna patch array receives and converts microwave power into a DC power for an array of smart actuators. To use microwave power effectively, the concept of a power allocation and distribution (PAD) circuit is adopted for networking a rectenna/actuator patch array. The PAD circuit is imbedded into a single embodiment of rectenna and actuator array. The thin-film microcircuit embodiment of PAD circuit adds insignificant amount of rigidity to membrane flexibility. Preliminary design and fabrication of PAD circuitry that consists of a few nodal elements were made for laboratory testing. The networked actuators were tested to correlate the network coupling effect, power allocation and distribution, and response time. The features of preliminary design are 16-channel computer control of actuators by a PCI board and the compensator for a power failure or leakage of one or more rectennas.

  14. An Updated Equilibrium Machine

    ERIC Educational Resources Information Center

    Schultz, Emeric

    2008-01-01

    A device that can demonstrate equilibrium, kinetic, and thermodynamic concepts is described. The device consists of a leaf blower attached to a plastic container divided into two chambers by a barrier of variable size and form. Styrofoam balls can be exchanged across the barrier when the leaf blower is turned on and various air pressures are…

  15. Photovoltaic conversion of laser energy

    NASA Technical Reports Server (NTRS)

    Stirn, R. J.

    1976-01-01

    The Schottky barrier photovoltaic converter is suggested as an alternative to the p/n junction photovoltaic devices for the conversion of laser energy to electrical energy. The structure, current, output, and voltage output of the Schottky device are summarized. The more advanced concepts of the multilayer Schottky barrier cell and the AMOS solar cell are briefly considered.

  16. From Teachers to Students: What Influences Early Childhood Educators to Pursue College Education

    ERIC Educational Resources Information Center

    Deutsch, Francine M.; Riffin, Catherine A.

    2013-01-01

    Underpaid and overworked, preschool teachers face multiple barriers in pursuing higher education. In the present study, we explored how logistical and financial barriers hinder early childhood education teachers and teacher's aides from taking college courses, as well as how academic self-concept and social support influence current enrollment.…

  17. Simulating Water Resource Disputes of Transboundary River: A Case Study of the Zhanghe River Basin, China

    NASA Astrophysics Data System (ADS)

    Yuan, Liang; He, Weijun; Liao, Zaiyi; Mulugeta Degefu, Dagmawi; An, Min; Zhang, Zhaofang

    2018-01-01

    Water resource disputes within transboundary river basin has been hindering the sustainable use of water resources and efficient management of environment. The problem is characterized by a complex information feedback loop that involves socio-economic and environmental systems. This paper presents a system dynamics based model that can simulate the dynamics of water demand, water supply, water adequacy and water allocation instability within a river basin. It was used for a case study in the Zhanghe River basin of China. The base scenario has been investigated for the time period between 2000 and 2050. The result shows that the Chinese national government should change the water allocation scheme of downstream Zhanghe River established in 1989, more water need to be allocated to the downstream cities and the actual allocation should be adjusted to reflect the need associated with the socio-economic and environmental changes within the region, and system dynamics improves the understanding of concepts and system interactions by offering a comprehensive and integrated view of the physical, social, economic, environmental, and political systems.

  18. Probabilistic migration modelling focused on functional barrier efficiency and low migration concepts in support of risk assessment.

    PubMed

    Brandsch, Rainer

    2017-10-01

    Migration modelling provides reliable migration estimates from food-contact materials (FCM) to food or food simulants based on mass-transfer parameters like diffusion and partition coefficients related to individual materials. In most cases, mass-transfer parameters are not readily available from the literature and for this reason are estimated with a given uncertainty. Historically, uncertainty was accounted for by introducing upper limit concepts first, turning out to be of limited applicability due to highly overestimated migration results. Probabilistic migration modelling gives the possibility to consider uncertainty of the mass-transfer parameters as well as other model inputs. With respect to a functional barrier, the most important parameters among others are the diffusion properties of the functional barrier and its thickness. A software tool that accepts distribution as inputs and is capable of applying Monte Carlo methods, i.e., random sampling from the input distributions of the relevant parameters (i.e., diffusion coefficient and layer thickness), predicts migration results with related uncertainty and confidence intervals. The capabilities of probabilistic migration modelling are presented in the view of three case studies (1) sensitivity analysis, (2) functional barrier efficiency and (3) validation by experimental testing. Based on the predicted migration by probabilistic migration modelling and related exposure estimates, safety evaluation of new materials in the context of existing or new packaging concepts is possible. Identifying associated migration risk and potential safety concerns in the early stage of packaging development is possible. Furthermore, dedicated material selection exhibiting required functional barrier efficiency under application conditions becomes feasible. Validation of the migration risk assessment by probabilistic migration modelling through a minimum of dedicated experimental testing is strongly recommended.

  19. How Community Colleges in Texas Prioritize Resources for Latino Men

    ERIC Educational Resources Information Center

    Rodriguez, Sarah L.; Garbee, Kelty T.; Miller, Ryan A.; Saenz, Victor B.

    2018-01-01

    This study explored how administrators at community colleges conceptualized change related to resource allocation and managing competing priorities to support targeted programming for Latino men. The study included the perspectives of 39 administrators from seven community colleges across Texas using concepts associated with institutional change…

  20. Report from a forum on US heart allocation policy.

    PubMed

    Kobashigawa, J A; Johnson, M; Rogers, J; Vega, J D; Colvin-Adams, M; Edwards, L; Meyer, D; Luu, M; Reinsmoen, N; Dipchand, A I; Feldman, D; Kormos, R; Mancini, D; Webber, S

    2015-01-01

    Since the latest revision in US heart allocation policy (2006), the landscape and volume of transplant waitlists have changed considerably. Advances in mechanical circulatory support (MCS) prolong survival, but Status 1A mortality remains high. Several patient subgroups may be disadvantaged by current listing criteria and geographical disparity remains in waitlist time. This forum on US heart allocation policy was organized to discuss these issues and highlight concepts for consideration in the policy development process. A 25-question survey on heart allocation policy was conducted. Among attendees/respondents were 84 participants with clinical/published experience in heart transplant representing 51 US transplant centers, and OPTN/UNOS and SRTR representatives. The survey results and forum discussions demonstrated very strong interest in change to a further-tiered system, accounting for disadvantaged subgroups and lowering use of exceptions. However, a heart allocation score is not yet viable due to the long-term viability of variables (used in the score) in an ever-developing field. There is strong interest in more refined prioritization of patients with MCS complications, highly sensitized patients and those with severe arrhythmias or restrictive physiology. There is also strong interest in distribution by geographic boundaries modified according to population. Differences of opinion exist between small and large centers.

  1. Conception and construction of an LPG tank using a composite membrane technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fuvel, P.; Claude, J.

    TECHNIGAZ and TOTAL C.F.P. have developed a new LPG storage technology derived from the membrane concept used for LNG storage and transportation. This technology called GMS uses a composite membrane as primary barrier. A 2 000 m/sup 3/ storage pilot unit, based on that concept, is under construction in TOTAL's refinery at DUNKIRK (France) since September 1983.

  2. Factors Influencing the Use of Biomedical Health Care by Rural Bolivian Anemic Women: Structural Barriers, Reproductive Status, Gender Roles, and Concepts of Anemia.

    PubMed

    Bedwell, Rebecca M; Spielvogel, Hilde; Bellido, Diva; Vitzthum, Virginia J

    2017-01-01

    Non-pregnant women from a rural town and its surrounding region were tested for anemia. During phase 1 (n = 181), anemic women received a written recommendation for low-cost purchase of iron pills at the nearest health center. They were subsequently interviewed on their actions and experiences. Estimated anemia prevalence among these non-pregnant women was 50% higher than the national average. Despite holding conceptualizations of anemia generally aligned with biomedical concepts, only 40% of anemic women attempted to obtain iron supplements from the health center. Town residents were about twice as likely to attempt to purchase pills as outside-town residents. Town women who were concurrently breastfeeding and menstruating, considered anemia most serious for women, and considered family health the shared responsibility of spouses were most likely to decide to purchase iron pills. Age, education, or native language did not negatively influence this health care behavior. Securing iron supplements involves individual trade-offs in the allocation of time, cost and effort. Nonetheless, suitably tailored programs can potentially harness local perceptions in the service of reducing anemia. Because of their comparatively high motivation to obtain iron supplements, targeting concurrently breastfeeding and menstruating women could have a positive cascade effect such that these women continue attending to their iron needs once they stop breastfeeding and if they become pregnant again. Because a sense of shared responsibility for family health appears to encourage women to attend to their own health, programs for women could involve their spouses. Complementing centralized availability, biomedical and traditional healers could distribute iron supplements on rotating visits to outlying areas and/or at highly attended weekly markets.

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    Pollution Prevention (P2) has evolved into one of DOE`s sprime strategies to meet environmental, fiscal, and worker safety obligations. P2 program planning, opportunity identification, and implementation tools were developed under the direction of the Waste Minimization Division (EM-334). Forty experts from EM, DP, ER and DOE subcontractors attended this 2-day workshop to formulate the incentives to drive utilization of these tools. Plenary and small working group sessions were held both days. Working Group 1 identified incentives to overcoming barriers in the area of P2 program planning and resource allocation. Working Group 2 identified mechanisms to drive the completion of P2more » assessments and generation of opportunities. Working Group 3 compiled and documented a broad range of potential P2 incentives that address fundamental barriers to implementation of cost effective opportunities.« less

  4. Equity weights in the allocation of health care: the rank-dependent QALY model.

    PubMed

    Bleichrodt, Han; Diecidue, Enrico; Quiggin, John

    2004-01-01

    This paper introduces the rank-dependent quality-adjusted life-years (QALY) model, a new method to aggregate QALYs in economic evaluations of health care. The rank-dependent QALY model permits the formalization of influential concepts of equity in the allocation of health care, such as the fair innings approach, and it includes as special cases many of the social welfare functions that have been proposed in the literature. An important advantage of the rank-dependent QALY model is that it offers a straightforward procedure to estimate equity weights for QALYs. We characterize the rank-dependent QALY model and argue that its central condition has normative appeal.

  5. Incorporating Concept Mapping in Project-Based Learning: Lessons from Watershed Investigations

    NASA Astrophysics Data System (ADS)

    Rye, James; Landenberger, Rick; Warner, Timothy A.

    2013-06-01

    The concept map tool set forth by Novak and colleagues is underutilized in education. A meta-analysis has encouraged teachers to make extensive use of concept mapping, and researchers have advocated computer-based concept mapping applications that exploit hyperlink technology. Through an NSF sponsored geosciences education grant, middle and secondary science teachers participated in professional development to apply computer-based concept mapping in project-based learning (PBL) units that investigated local watersheds. Participants attended a summer institute, engaged in a summer through spring online learning academy, and presented PBL units at a subsequent fall science teachers' convention. The majority of 17 teachers who attended the summer institute had previously used the concept mapping strategy with students and rated it highly. Of the 12 teachers who continued beyond summer, applications of concept mapping ranged from collaborative planning of PBL projects to building students' vocabulary to students producing maps related to the PBL driving question. Barriers to the adoption and use of concept mapping included technology access at the schools, lack of time for teachers to advance their technology skills, lack of student motivation to choose to learn, and student difficulty with linking terms. In addition to mitigating the aforementioned barriers, projects targeting teachers' use of technology tools may enhance adoption by recruiting teachers as partners from schools as well as a small number that already are proficient in the targeted technology and emphasizing the utility of the concept map as a planning tool.

  6. A Systematic Investigation on Barriers and Critical Success Factors for Clinical Information Systems in Integrated Care Settings.

    PubMed

    Hoerbst, A; Schweitzer, M

    2015-08-13

    Clinical Information Systems (CIS) have ever since the introduction of information technology in healthcare played an important role to support healthcare professionals and the process of treatment. With the rise of the concept of integrated care organizational borders, the sole focus on data aggregation or healthcare professionals as users disappear more and more. The manuscript discusses the concept of CISs and investigates critical success factors for CISs in the context of integrated care and in the course of time. In order to identify critical success factors and barriers for CISs a systematic literature review was conducted based on the results from PubMed and Cochrane, using MaxQDA. Search results were thereby limited to reviews or meta-analysis. We have found 1919 references of which 40 met the inclusion criteria. The analysis of the manuscripts resulted in a comprehensive list of success factors and barriers related to CISs in integrated care settings. Most barriers were user-related whereas for the success factors an even distribution of organizational, technical and user-related factors was observed. The vast majority of publications was focused on healthcare professionals. It is important to incorporate experiences made/ collected over time, as the problems encountered seem to remain almost unvaried. In order to support further systematic investigations on the topic it is necessary to rethink existing concepts and definitions to realign them with the ideas of integrated care.

  7. The Effect of Price Competition on Weapon System Acquisition costs

    DTIC Science & Technology

    1979-09-01

    barriers to entry into the weapons production indistry. This practice also reduces the scope of price-compcLtive reprocurement. The implicit tying of R&D... removaL . ’For the serrinal work in this area see H. Leibenstein, "Allocative Efficiency vs. ,h-Efficiency," American Econcmic Review (June 1966). I1 3...If the use of price competition to assign production removes any extra-normal returns earned under sole-source pro- curement policies, firms will no

  8. Man's Impact on the Environment: The Barrier Beach as an Ecosystem. Update.

    ERIC Educational Resources Information Center

    Brevard County School Board, Cocoa, FL.

    This environmental education program emphasizes the cause and effect of change in a barrier beach ecosystem with special attention given to man and his role in environmental change. Concepts are employed from the natural and social sciences to investigate environmental problems. The units are designed around these questions: (1) What is an…

  9. The "Language Barrier" in Private Online Tutoring: From an Innocuous Concept to a Neoliberal Marketing Tool

    ERIC Educational Resources Information Center

    Kozar, Olga

    2014-01-01

    The "language barrier" is a common buzzword in Russian-English teaching discourse that has not yet been critically investigated. This study contemplates a recently emerging phenomenon of private online language tutoring in Russia through investigation of this popular phrase. The paper draws on Critical Discourse Analysis to explore…

  10. Barriers to College Students Learning How Rocks Form

    ERIC Educational Resources Information Center

    Kortz, Karen M.; Murray, Daniel P.

    2009-01-01

    Students do not have a good understanding of how rocks form. Instead, they have many non-scientific alternative conceptions to explain different aspects of rock formation. Using 10 interviews and nearly 200 questionnaires filled out by students at four different colleges, we identified many alternative conceptions students have about rock…

  11. Using Technology to Facilitate Reasoning: Lifting the Fog from Linear Algebra

    ERIC Educational Resources Information Center

    Berry, John S.; Lapp, Douglas A.; Nyman, Melvin A.

    2008-01-01

    This article discusses student difficulties in grasping concepts from linear algebra. Using an example from an interview with a student, we propose changes that might positively impact student understanding of concepts within a problem-solving context. In particular, we illustrate barriers to student understanding and suggest technological…

  12. Reconceiving Barriers for Democratic Health Education in Danish Schools: An Analysis of Institutional Rationales

    ERIC Educational Resources Information Center

    Danielsen, Dina; Bruselius-Jensen, Maria; Laitsch, Daniel

    2017-01-01

    Health promotion and education researchers and practitioners advocate for more democratic approaches to school-based health education, including participatory teaching methods and the promotion of a broad and positive concept of health and health knowledge, including aspects of the German educational concept of "bildung." Although…

  13. A Policy Process Model as a Tool of Educational Governance.

    ERIC Educational Resources Information Center

    Este, Robert A.

    An examination of the relevant literature reveals that "policy" means different things to different people. Among the concepts that emerge when these meanings are reviewed are that policies are intentional, decision-based, goal-oriented, and conditional; they lead to results, balance facts and values, and allocate resources; and they…

  14. Internal Labor Markets: An Empirical Investigation.

    ERIC Educational Resources Information Center

    Mahoney, Thomas A.; Milkovich, George T.

    Methods of internal labor market analysis for three organizational areas are presented, along with some evidence about the validity and utility of conceptual descriptions of such markets. The general concept of an internal labor market refers to the process of pricing and allocation of manpower resources with an employing organization and rests…

  15. Theoretical Definition of Instructor Role in Computer-Managed Instruction.

    ERIC Educational Resources Information Center

    McCombs, Barbara L.; Dobrovolny, Jacqueline L.

    This report describes the results of a theoretical analysis of the ideal role functions of the Computer Managed Instruction (CMI) instructor. Concepts relevant to instructor behavior are synthesized from both cognitive and operant learning theory perspectives, and the roles allocated to instructors by seven large-scale operational CMI systems are…

  16. Direct Broadcast Satellites: An Interview with Hartford Gunn.

    ERIC Educational Resources Information Center

    Library Hi Tech, 1984

    1984-01-01

    In this interview with Hartford Gunn, Vice-President of Program Development for Satellite Television Corporation (STC), the concept of direct broadcast by satellite (DBS) is explored. Allocation of radio frequencies, services provided by DBS network, home installation and purchase of dish antenna, and comparison of DBS with cable television are…

  17. Proyectos de Educacion Migrante (Migrant Education Projects).

    ERIC Educational Resources Information Center

    Gonzalez, Ramon; Garcia, Jose D.

    Written in Spanish and English for project personnel, parents, and others interested in migrant education, the booklet summarizes general concepts and requirements behind Title I-Migrant activities in Oregon, which has been allocated $4,439,341 in Title I-Migrant funds for fiscal year 1980. Following brief definitions of important terms,…

  18. Human Parental Care: Universal Goals, Cultural Strategies, Individual Behavior.

    ERIC Educational Resources Information Center

    LeVine, Robert A.

    1988-01-01

    A model of parental behavior as adaptation in agrarian and urban-industrial societies is proposed and examined in light of the evidence in this volume. The model is based on the concept of parental investment strategies for allocating time, attention, and domestic resources to raising children. (RH)

  19. Computer-Assisted Instruction: One Aid for Teachers of Reading.

    ERIC Educational Resources Information Center

    Rauch, Margaret; Samojeden, Elizabeth

    Computer assisted instruction (CAI), an instructional system with direct interaction between the student and the computer, can be a valuable aid for presenting new concepts, for reinforcing of selective skills, and for individualizing instruction. The advantages CAI provides include self-paced learning, more efficient allocation of classroom time,…

  20. FIRESCOPE: a new concept in multiagency fire suppression coordination

    Treesearch

    Richard A. Chase

    1980-01-01

    FIRESCOPE is a system developed to improve the capability of firefighting agencies in southern California in allocating and managing fire suppression resources. The system provides an effective and efficient solution to operational coordination requirements and problems of the major fire protection agencies serving the southern California urban-wildland complex. Major...

  1. Efficient funding: a path to improving Aboriginal healthcare in Australia?

    PubMed

    Lloyd, Jane E; Wise, Marilyn J

    2010-11-01

    To identify the factors that contribute to the under-resourcing of Aboriginal health and to explore the impact that funding arrangements have on the implementation of Aboriginal health policy. Qualitative study based on 35 in-depth interviews with a purposive sample of frontline health professionals involved in health policy and service provision in the Northern Territory. Participants described three factors that contributed to the under-resourcing of Aboriginal health: inefficient funding arrangements, mainstream programs being inappropriate for Aboriginal Australians, and competing interests determining the allocation of resources. Insufficient capacity within the healthcare system undermines the multilevel implementation process whereby organisations need to have the capacity to recognise new policy ideas, assess their relevance to their existing work and strategic plan and to be able to incorporate the relevant new ideas into day-to-day practice. Insufficient resources for Aboriginal health were found to be a barrier to implementing Aboriginal health policy. Inadequate resources result from the cumbersome allocation of funding rather than simply the amount of funding provided to Aboriginal healthcare. Monitoring government performance and ensuring the efficient allocation of funds would allow us to develop the delivery system for Aboriginal healthcare and therefore provide greater opportunities to capitalise on current interventions and future efforts.

  2. How to use concept mapping to identify barriers and facilitators of an electronic quality improvement intervention.

    PubMed

    van Engen-Verheul, Mariëtte; Peek, Niels; Vromen, Tom; Jaspers, Monique; de Keizer, Nicolette

    2015-01-01

    Systematic quality improvement (QI) interventions are increasingly used to change complex health care systems. Results of randomized clinical trials can provide quantitative evidence whether QI interventions were effective but they do not teach us why and how QI was (not) achieved. Qualitative research methods can answer these questions but typically involve only a small group of respondents against high resources. Concept mapping methodology overcomes these drawbacks by integrating results from qualitative group sessions with multivariate statistical analysis to represent ideas of diverse stakeholders visually on maps in an efficient way. This paper aims to describe how to use concept mapping to qualitatively gain insight into barriers and facilitators of an electronic QI intervention and presents experiences with the method from an ongoing case study to evaluate a QI system in the field of cardiac rehabilitation in the Netherlands.

  3. Sustainability in Health care by Allocating Resources Effectively (SHARE) 9: conceptualising disinvestment in the local healthcare setting.

    PubMed

    Harris, Claire; Green, Sally; Ramsey, Wayne; Allen, Kelly; King, Richard

    2017-09-08

    This is the ninth in a series of papers reporting a program of Sustainability in Health care by Allocating Resources Effectively (SHARE) in a local healthcare setting. The disinvestment literature has broadened considerably over the past decade; however there is a significant gap regarding systematic, integrated, organisation-wide approaches. This debate paper presents a discussion of the conceptual aspects of disinvestment from the local perspective. Four themes are discussed: Terminology and concepts, Motivation and purpose, Relationships with other healthcare improvement paradigms, and Challenges to disinvestment. There are multiple definitions for disinvestment, multiple concepts underpin the definitions and multiple alternative terms convey these concepts; some definitions overlap and some are mutually exclusive; and there are systematic discrepancies in use between the research and practice settings. Many authors suggest that the term 'disinvestment' should be avoided due to perceived negative connotations and propose that the concept be considered alongside investment in the context of all resource allocation decisions and approached from the perspective of optimising health care. This may provide motivation for change, reduce disincentives and avoid some of the ethical dilemmas inherent in other disinvestment approaches. The impetus and rationale for disinvestment activities are likely to affect all aspects of the process from identification and prioritisation through to implementation and evaluation but have not been widely discussed. A need for mechanisms, frameworks, methods and tools for disinvestment is reported. However there are several health improvement paradigms with mature frameworks and validated methods and tools that are widely-used and well-accepted in local health services that already undertake disinvestment-type activities and could be expanded and built upon. The nature of disinvestment brings some particular challenges for policy-makers, managers, health professionals and researchers. There is little evidence of successful implementation of 'disinvestment' projects in the local setting, however initiatives to remove or replace technologies and practices have been successfully achieved through evidence-based practice, quality and safety activities, and health service improvement programs. These findings suggest that the construct of 'disinvestment' may be problematic at the local level. A new definition and two potential approaches to disinvestment are proposed to stimulate further research and discussion.

  4. Use of various contraceptive methods and time of conception in a community-based population.

    PubMed

    Kaplan, Boris; Nahum, Ravit; Yairi, Yael; Hirsch, Michael; Pardo, Josef; Yogev, Yariv; Orvieto, Raoul

    2005-11-01

    To investigate the association between method of contraception and time to conception in a normal community-based population. Prospective, cross-sectional, survey. Large comprehensive ambulatory women's health center. One thousand pregnant women at their first prenatal obstetrics visit were asked to complete a self-report questionnaire. The return to fertility was analyzed by type of contraceptive method, duration of use, and other sociodemographic variables. Response rate was 80% (n=798). Mean age of the patients was 29.9+/-5 years. Seventy-five percent had used a contraceptive before trying to conceive: 80% oral contraceptives, 8% intrauterine device, and 7% barrier methods. Eighty-six percent conceived spontaneously. Contraceptive users had a significantly higher conception rate than nonusers in the first 3 months from their first attempt at pregnancy. Type of contraception was significantly correlated with time to conception. Pregnancy rates within 6 months of the first attempt was 60% for oral contraceptive users compared to 70 and 81% for the intrauterine device and barrier method groups, respectively. There was no correlation between time to conception and parity or duration of contraceptive use. Other factors found to be significantly related to time to conception were older age of both partners and higher body mass index. Contraception use before a planned pregnancy does not appear to affect ease of conception. Type of method used, although not duration of use, may influence the time required to conceive.

  5. Mechanism of supporting sub-communicator collectives with O(64) counters as opposed to one counter for each sub-communicator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kumar, Sameer; Mamidala, Amith R.; Ratterman, Joseph D.

    A system and method for enhancing barrier collective synchronization on a computer system comprises a computer system including a data storage device. The computer system includes a program stored in the data storage device and steps of the program being executed by a processor. The system includes providing a plurality of communicators for storing state information for a bather algorithm. Each communicator designates a master core in a multi-processor environment of the computer system. The system allocates or designates one counter for each of a plurality of threads. The system configures a table with a number of entries equal tomore » the maximum number of threads. The system sets a table entry with an ID associated with a communicator when a process thread initiates a collective. The system determines an allocated or designated counter by searching entries in the table.« less

  6. Mechanism of supporting sub-communicator collectives with O(64) counters as opposed to one counter for each sub-communicator

    DOEpatents

    Kumar, Sameer; Mamidala, Amith R.; Ratterman, Joseph D.; Blocksome, Michael; Miller, Douglas

    2013-09-03

    A system and method for enhancing barrier collective synchronization on a computer system comprises a computer system including a data storage device. The computer system includes a program stored in the data storage device and steps of the program being executed by a processor. The system includes providing a plurality of communicators for storing state information for a bather algorithm. Each communicator designates a master core in a multi-processor environment of the computer system. The system allocates or designates one counter for each of a plurality of threads. The system configures a table with a number of entries equal to the maximum number of threads. The system sets a table entry with an ID associated with a communicator when a process thread initiates a collective. The system determines an allocated or designated counter by searching entries in the table.

  7. The mechanism of valence-space metaphors: ERP evidence for affective word processing.

    PubMed

    Xie, Jiushu; Wang, Ruiming; Chang, Song

    2014-01-01

    Embodied cognition contends that the representation and processing of concepts involve perceptual, somatosensory, motoric, and other physical re-experiencing information. In this view, affective concepts are also grounded in physical information. For instance, people often say "feeling down" or "cheer up" in daily life. These phrases use spatial information to understand affective concepts. This process is referred to as valence-space metaphor. Valence-space metaphors refer to the employment of spatial information (lower/higher space) to elaborate affective concepts (negative/positive concepts). Previous studies have demonstrated that processing affective words affects performance on a spatial detection task. However, the mechanism(s) behind this effect remain unclear. In the current study, we hypothesized that processing affective words might produce spatial information. Consequently, spatial information would affect the following spatial cue detection/discrimination task. In Experiment 1, participants were asked to remember an affective word. Then, they completed a spatial cue detection task while event-related potentials were recorded. The results indicated that the top cues induced enhanced amplitude of P200 component while participants kept positive words relative to negative words in mind. On the contrary, the bottom cues induced enhanced P200 amplitudes while participants kept negative words relative to positive words in mind. In Experiment 2, we conducted a behavioral experiment that employed a similar paradigm to Experiment 1, but used arrows instead of dots to test the attentional nature of the valence-space metaphor. We found a similar facilitation effect as found in Experiment 1. Positive words facilitated the discrimination of upper arrows, whereas negative words facilitated the discrimination of lower arrows. In summary, affective words might activate spatial information and cause participants to allocate their attention to corresponding locations. Valence-space metaphors might be grounded in attention allocation.

  8. Evaluation of health resource utilization efficiency in community health centers of Jiangsu Province, China.

    PubMed

    Xu, Xinglong; Zhou, Lulin; Antwi, Henry Asante; Chen, Xi

    2018-02-20

    While the demand for health services keep escalating at the grass roots or rural areas of China, a substantial portion of healthcare resources remain stagnant in the more developed cities and this has entrenched health inequity in many parts of China. At its conception, China's Deepen Medical Reform started in 2012 was intended to flush out possible disparities and promote a more equitable and efficient distribution of healthcare resources. Nearly half a decade of this reform, there are uncertainties as to whether the attainment of the objectives of the reform is in sight. Using a hybrid of panel data analysis and an augmented data envelopment analysis (DEA), we model human resources, material, finance to determine their technical and scale efficiency to comprehensively evaluate the transverse and longitudinal allocation efficiency of community health resources in Jiangsu Province. We observed that the Deepen Medical Reform in China has led to an increase concern to ensure efficient allocation of community health resources by health policy makers in the province. This has led to greater efficiency in health resource allocation in Jiangsu in general but serious regional or municipal disparities still exist. Using the DEA model, we note that the output from the Community Health Centers does not commensurate with the substantial resources (human resources, materials, and financial) invested in them. We further observe that the case is worst in less-developed Northern parts of Jiangsu Province. The government of Jiangsu Province could improve the efficiency of health resource allocation by improving the community health service system, rationalizing the allocation of health personnel, optimizing the allocation of material resources, and enhancing the level of health of financial resource allocation.

  9. Allocation and management issues in multiple-transaction open access transmission networks

    NASA Astrophysics Data System (ADS)

    Tao, Shu

    This thesis focuses on some key issues related to allocation and management by the independent grid operator (IGO) of unbundled services in multiple-transaction open access transmission networks. The three unbundled services addressed in the thesis are transmission real power losses, reactive power support requirements from generation sources, and transmission congestion management. We develop the general framework that explicitly represents multiple transactions undertaken simultaneously in the transmission grid. This framework serves as the basis for formulating various problems treated in the thesis. We use this comprehensive framework to develop a physical-flow-based mechanism to allocate the total transmission losses to each transaction using the system. An important property of the allocation scheme is its capability to effectively deal with counter flows that result in the presence of specific transactions. Using the loss allocation results as the basis, we construct the equivalent loss compensation concept and apply it to develop flexible and effective procedures for compensating losses in multiple-transaction networks. We present a new physical-flow-based mechanism for allocating the reactive power support requirements provided by generators in multiple-transaction networks. The allocatable reactive support requirements are formulated as the sum of two specific components---the voltage magnitude variation component and the voltage angle variation component. The formulation utilizes the multiple-transaction framework and makes use of certain simplifying approximations. The formulation leads to a natural allocation as a function of the amount of each transaction. The physical interpretation of each allocation as a sensitivity of the reactive output of a generator is discussed. We propose a congestion management allocation scheme for multiple-transaction networks. The proposed scheme determines the allocation of congestion among the transactions on a physical-flow basis. It also proposes a congestion relief scheme that removes the congestion attributed to each transaction on the network in a least-cost manner to the IGO and determines the appropriate transmission charges to each transaction for its transmission usage. The thesis provides a compendium of problems that are natural extensions of the research results reported here and appear to be good candidates for future work.

  10. Extreme D'Hondt and round-off effects in voting computations

    NASA Astrophysics Data System (ADS)

    Konstantinov, M. M.; Pelova, G. B.

    2015-11-01

    D'Hondt (or Jefferson) method and Hare-Niemeyer (or Hamilton) method are widely used worldwide for seat allocation in proportional systems. Everything seems to be well known in this area. However, this is not the case. For example the D'Hondt method can violate the quota rule from above but this effect is not analyzed as a function of the number of parties and/or the threshold used. Also, allocation methods are often implemented automatically as computer codes in machine arithmetic believing that following the IEEE standards for double precision binary arithmetics would guarantee correct results. Unfortunately this may not happen not only for double precision arithmetic (usually producing 15-16 true decimal digits) but also for any relative precision of the underlying binary machine arithmetics. This paper deals with the following new issues.Find conditions (threshold in particular) such that D'Hondt seat allocation violates maximally the quota rule. Analyze possible influence of rounding errors in the automatic implementation of Hare-Niemeyer method in machine arithmetic.Concerning the first issue, it is known that the maximal deviation of D'Hondt allocation from upper quota for the Bulgarian proportional system (240 MP and 4% barrier) is 5. This fact had been established in 1991. A classical treatment of voting issues is the monograph [1], while electoral problems specific for Bulgaria have been treated in [2, 4]. The effect of threshold on extreme seat allocations is also analyzed in [3]. Finally we would like to stress that Voting Theory may sometimes be mathematically trivial but always has great political impact. This is a strong motivation for further investigations in this area.

  11. Classification of Schedule Management Barriers through Concept Mapping

    DTIC Science & Technology

    2009-03-26

    of ballistic missiles and space systems were considered essential for national defense. Intense competition between the military services and their...Having identified only two papers that indirectly addressed potential barriers to schedule management, the search was expanded to find comments made...in books and papers that 17 referenced reasons why schedule management may not be adopted or done effectively within an organization

  12. Thinly disguised contempt: a barrier to excellence.

    PubMed

    Brown-Stewart, P

    1987-04-01

    Many elements in contemporary leadership and management convey contempt for employees. "Thinly disguised contempt," a concept introduced by Peters and Austin in A Passion For Excellence, explains many barriers to the achievement of excellence in corporations across disciplines. Health care executives and managers can learn from the errors of corporate management and avoid replicating these errors in the health care industry.

  13. Changing Roles, Changing Relationships: Parent-Professional Collaboration on Behalf of Children with Emotional Disabilities. Families as Allies Project.

    ERIC Educational Resources Information Center

    Vosler-Hunter, Richard W.

    This handbook aims to help parents of emotionally disabled children and professionals serving emotionally disabled children to put the concept of collaboration into practice, to understand the barriers to collaboration, and to develop strategies to overcome those barriers and promote a working partnership. Factors that may influence or inhibit the…

  14. Environmental factors and their role in community integration after spinal cord injury.

    PubMed

    Lysack, Cathy; Komanecky, Marie; Kabel, Allison; Cross, Katherine; Neufeld, Stewart

    2007-01-01

    The International Classification of Functioning, Disability and Health (ICF) model presents an opportunity to better understand previously neglected longterm social outcomes after traumatic spinal cord injury (SCI), especially the experience of participation. The study explored the relationship between perceived environmental barriers and perceived community integration (a participation proxy) in a sample of adults with traumatic SCI. The study interviewed African American and White women and men (n = 136) who had lived with SCI for an average of 11.5 years. Participants reported environmental barriers at twice the level indicated by previous studies; the natural environment and the policies of government were the most problematic. Levels of community integration were also high. Data suggest a significant relationship (p < .01) between perceived environmental barriers and community integration for adults with SCI, providing support for the ICF model. Improved measures and more sophisticated concepts and theories are needed to explicate the relationship between environmental factors and participation concepts in the ICE With respect to practice, occupational therapists need to be aware that removal of environmental barriers is only a first step in the more complex effort to facilitate optimal community integration after SCI.

  15. Teaching Business Communication on the Production Line: A Case Study.

    ERIC Educational Resources Information Center

    Moore, Richard W.

    1993-01-01

    Analyzes the communication training received by over 4,000 workers as part of an effort to implement a team concept production system at a General Motors plant. Presents an overview of the team concept training. Discusses five barriers to effective training, four successful instructional methods, and implications for business communication. (RS)

  16. Spectroscopy and photochemistry of humic acids

    NASA Astrophysics Data System (ADS)

    Sokolova, I. V.; Vershinin, N. O.; Skobczova, K. A.; Tchaikovskaya, O. N.; Mayer, G. V.

    2018-04-01

    Spectroscopy and photochemistry of humic acids are discussed. The samples of HAs fractions were obtained from Fluka Chemical Co and prepared from peat of Western Siberia region. The comparative analysis of these acids with the sample of humic acids allocated from brown coal is carried out. A specific feature of the reactor is the use of barrier discharge excilamp (KrCl) with radiation wavelength λ = 222 nm. Influence of the received humic acids on process of photodegradation of herbicide - 2.4-dichlorophenoxyacetic acid is considered.

  17. Performance analysis of optimal power allocation in wireless cooperative communication systems

    NASA Astrophysics Data System (ADS)

    Babikir Adam, Edriss E.; Samb, Doudou; Yu, Li

    2013-03-01

    Cooperative communication has been recently proposed in wireless communication systems for exploring the inherent spatial diversity in relay channels.The Amplify-and-Forward (AF) cooperation protocols with multiple relays have not been sufficiently investigated even if it has a low complexity in term of implementation. We consider in this work a cooperative diversity system in which a source transmits some information to a destination with the help of multiple relay nodes with AF protocols and investigate the optimality of allocating powers both at the source and the relays system by optimizing the symbol error rate (SER) performance in an efficient way. Firstly we derive a closedform SER formulation for MPSK signal using the concept of moment generating function and some statistical approximations in high signal to noise ratio (SNR) for the system under studied. We then find a tight corresponding lower bound which converges to the same limit as the theoretical upper bound and develop an optimal power allocation (OPA) technique with mean channel gains to minimize the SER. Simulation results show that our scheme outperforms the equal power allocation (EPA) scheme and is tight to the theoretical approximation based on the SER upper bound in high SNR for different number of relays.

  18. Optimal allocation of trend following strategies

    NASA Astrophysics Data System (ADS)

    Grebenkov, Denis S.; Serror, Jeremy

    2015-09-01

    We consider a portfolio allocation problem for trend following (TF) strategies on multiple correlated assets. Under simplifying assumptions of a Gaussian market and linear TF strategies, we derive analytical formulas for the mean and variance of the portfolio return. We construct then the optimal portfolio that maximizes risk-adjusted return by accounting for inter-asset correlations. The dynamic allocation problem for n assets is shown to be equivalent to the classical static allocation problem for n2 virtual assets that include lead-lag corrections in positions of TF strategies. The respective roles of asset auto-correlations and inter-asset correlations are investigated in depth for the two-asset case and a sector model. In contrast to the principle of diversification suggesting to treat uncorrelated assets, we show that inter-asset correlations allow one to estimate apparent trends more reliably and to adjust the TF positions more efficiently. If properly accounted for, inter-asset correlations are not deteriorative but beneficial for portfolio management that can open new profit opportunities for trend followers. These concepts are illustrated using daily returns of three highly correlated futures markets: the E-mini S&P 500, Euro Stoxx 50 index, and the US 10-year T-note futures.

  19. Effects of an injectable trace mineral supplement on first-service conception rate of dairy cows.

    PubMed

    Vanegas, J A; Reynolds, J; Atwill, E R

    2004-11-01

    A total of 825 dairy cows from a commercial dairy farm in central California were used to evaluate effects of one or 2 doses of an injectable trace mineral supplement containing 20 mg/mL of zinc, 20 mg/mL of manganese, 5 mg/mL of selenium, and 10 mg/mL of copper on first-service conception rate. Cows were randomly allocated into treatment or control group to either a single dose (experiment 1) or a double dose (experiment 2) of injected supplement. Allocation was based on days in lactation for experiment 1 and the length of gestation periods for experiment 2. In experiment 1, cows 38 to 45 d in lactation (n = 190) received a single dose of 5 mL of injected supplement. Similar cows were used as controls (n = 227). In experiment 2, cows and pregnant heifers received an initial injection of 5 mL of the mineral supplement from 2 to 3 wk precalving (n = 186). An equal dose was repeated 38 to 45 d in lactation. A similar group of cows and pregnant heifers served as controls for experiment 2 (n = 222). Health and reproductive events postcalving were recorded. In experiment 1, the odds of first-service conception were not significantly different for cows receiving a one-dose regimen of minerals compared with untreated control cows; conception rates were 26.8 and 27.5% for experiment 1 treatment and control groups, respectively. In experiment 1, the odds of first-service conception were significantly lower (odds ratio = 0.66) for cows and heifers given the 2-dose regimen of minerals compared with untreated controls; overall conception rates were 21.5 and 31.5% for experiment 2 treatment and control groups, respectively. In this intensively managed dairy herd, a single dose of injected trace minerals before breeding had no beneficial effects on first-service conception rate. However, dairy cows receiving a dose of trace minerals before calving and another dose before breeding had lower conception at first service.

  20. Toward Nucleating the Concept of the Water Resource Recovery Facility (WRRF): Perspective from the Principal Actors.

    PubMed

    Coats, Erik R; Wilson, Patrick I

    2017-04-18

    Wastewater resource recovery has been advocated for decades; necessary structural pathways were long-ago articulated, and established and emerging technologies exist. Nevertheless, broad wastewater valorization remains elusive. In considering implementation barriers, the argument is made that decision-makers focus on avoiding permit violations and negative publicity by embracing a conservative/safe approach-seemingly ignoring research on economic/environmental benefits. Conversely positing that economics is a primary barrier, we investigated, characterized, and described nontechnical socio-political barriers to realizing wastewater resource recovery. Principal actors in the Pacific NW region of the U.S. (representing a progressive populace facing stringent water quality regulations) were interviewed. Results revealed that economics were, indeed, the primary barrier to implementation/expansion of the WRRF concept. Consistent throughout interviews was a prevalent sense that the "cost of doing something (different)" was a principal consideration in resource recovery actions/policies. Moreover, "economics drives decisions," and "95% the bottom line is money. Show return on investment, it will get people's attention." Who pays was also a concern: "Government isn't going to pay. The states and Federal government won't give any grants, and we can't raise rates." Applying business case evaluations was seen as a pathway to actualizing resource recovery. Most encouragingly, the consensus was that resource recovery is a necessary future paradigm, and that real barriers are surmountable.

  1. Harnessing Scientific and Technological Advances to Improve Equity in Kidney Allocation Policies.

    PubMed

    Tambur, A R; Audry, B; Antoine, C; Suberbielle, C; Glotz, D; Jacquelinet, C

    2017-12-01

    We reported that current assignment of HLA-DQ is a barrier to organ allocation. Here we simulated the impact of incorporating HLA-DQ antigens and antibodies as A/B and αβ allelic variants, respectively, on calculated panel reactive antibody (cPRA) and probability of finding potential compatible donors (PCD). A cohort of 1224 donors and 2075 sensitized candidates was analyzed using HLA-DQαβ allelic (study) versus serologic (current practice) nomenclature. A significant (p < 10 -4 ) decrease in cPRA was observed with higher impact for male versus female, and first transplant versus retransplant (p < 10 -4 ), affecting mostly patients with moderate cPRA (30-80%). Consequently, the number of patients qualifying for 100% cPRA points according to the United Network for Organ Sharing-Kidney Allocation System decreased by 37%. More critically, by using allelic versus serologic nomenclature for HLA-DQ, the number of PCDs for all patients was increased, with male and first-transplant patients showing a higher expansion compared with female and retransplants. Patients of blood group O showed the highest benefit. The goal of reporting unacceptable antigens is to improve accuracy of virtual crossmatching and increase the likelihood of finding immunologically compatible donors. Our simulation provides strong support for the need to re-evaluate the use of allele typing and how HLA-DQ antigens and antibodies are incorporated into allocation policies to ensure equity. © 2017 The American Society of Transplantation and the American Society of Transplant Surgeons.

  2. Older Adult Education: New Public Pedagogy in 21st Century Taiwan

    ERIC Educational Resources Information Center

    Lee, Ya-hui

    2015-01-01

    The lifelong learning concept of "never too late to learn" advocated by Confucius has gradually become rooted in the lives of Taiwanese adults and seniors. In response to the impact of population ageing and low fertility rates, numerous elementary schools, junior high schools, and universities have allocated resources and space to…

  3. Key Concepts of Teams in an Organisation. Information Bank Working Paper Number 2541.

    ERIC Educational Resources Information Center

    Marsh, D. T.

    Teams in an organization are more than cooperative working groups. Advantages of group work, as opposed to individual work, include producing a better end result, providing satisfaction for the individual and the organization, and assisting the organization through coordination and work allocation. Disadvantages of group work include producing a…

  4. Assignment Of Finite Elements To Parallel Processors

    NASA Technical Reports Server (NTRS)

    Salama, Moktar A.; Flower, Jon W.; Otto, Steve W.

    1990-01-01

    Elements assigned approximately optimally to subdomains. Mapping algorithm based on simulated-annealing concept used to minimize approximate time required to perform finite-element computation on hypercube computer or other network of parallel data processors. Mapping algorithm needed when shape of domain complicated or otherwise not obvious what allocation of elements to subdomains minimizes cost of computation.

  5. 42 CFR 495.340 - As-needed HIT PAPD update and as-needed HIT IAPD update requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.340 As... document or the HIT implementation advance planning document. (d) A change in implementation concept or a change to the scope of the project. (e) A change to the approved cost allocation methodology. ...

  6. 42 CFR 495.340 - As-needed HIT PAPD update and as-needed HIT IAPD update requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.340 As... document or the HIT implementation advance planning document. (d) A change in implementation concept or a change to the scope of the project. (e) A change to the approved cost allocation methodology. ...

  7. Updating Rurality Index for Small Areas in Spain

    ERIC Educational Resources Information Center

    Prieto-Lara, Elisa; Ocana-Riola, Ricardo

    2010-01-01

    Nowadays, there is a wide debate about what rural means. An operational definition of rural concept is essential in order to measure health problems, optimize resource allocation and facilitate decision making aimed at closing the gap on inequity between areas. In 2005, the rurality index for Small Areas in Spain (IRAP) was developed using the…

  8. Academic Success Foundation: Enhancing Academic Integrity through Mobile Learning

    ERIC Educational Resources Information Center

    Hanbidge, Alice Schmidt; Mackenzie, Amanda; Sanderson, Nicole; Scholz, Kyle; Tin, Tony

    2017-01-01

    How do we close the gap between the lack of academic experience incoming students have--with the expectation that students know the rules of writing and taking exams? Academic integrity (AI) is essential in post-secondary academia yet insufficient time is allocated to teaching and practicing its concepts. Talks at orientation, lectures in the…

  9. Cognitive Conflict and Situational Interest as Factors Influencing Conceptual Change

    ERIC Educational Resources Information Center

    Kang, Hunsik; Scharmann, Lawrence C.; Kang, Sukjin; Noh, Taehee

    2010-01-01

    In this study, we investigated the relationships among cognitive conflict and situational interest induced by a discrepant event, attention and effort allocated to learning, and conceptual change in learning the concept of density. Subjects were 183 seventh graders from six middle schools in Seoul, Korea. A preconception test, a test of responses…

  10. The Lummi Indians and the Canadian/American Pacific Salmon Treaty.

    ERIC Educational Resources Information Center

    Boxberger, Daniel L.

    1988-01-01

    Explores the probable impact of the 1985 international Pacific Salmon Treaty on the Lummi tribe's catch of Fraser River salmon and economic well-being. Discusses the 1974 Boldt Decision, which allocated half of Washington State's salmon catch to treaty tribes, and contradictions in the federal government's conception of international treaties. (SV)

  11. A new multicriteria risk mapping approach based on a multiattribute frontier concept

    Treesearch

    Denys Yemshanov; Frank H. Koch; Yakov Ben-Haim; Marla Downing; Frank Sapio; Marty Siltanen

    2013-01-01

    Invasive species risk maps provide broad guidance on where to allocate resources for pest monitoring and regulation, but they often present individual risk components (such as climatic suitability, host abundance, or introduction potential) as independent entities. These independent risk components are integrated using various multicriteria analysis techniques that...

  12. Functional Allocation with Airborne Self-Separation Evaluated in a Piloted Simulation

    NASA Technical Reports Server (NTRS)

    Wing, David J.; Murdoch, Jennifer L.; Chamberlain, James P.; Consiglio, Maria C.; Hoardley, Sherwood T.; Hubbs, Clay E.; Palmer, Michael T.

    2010-01-01

    A human-in-the-loop simulation experiment was designed and conducted to evaluate an airborne self-separation concept. The activity supports the National Aeronautics and Space Administration s (NASA) research focus on function allocation for separation assurance. The objectives of the experiment were twofold: (1) use experiment design features in common with a companion study of ground-based automated separation assurance to promote comparability, and (2) assess agility of self-separation operations in managing trajectory-changing events in high traffic density, en-route operations with arrival time constraints. This paper describes the experiment and presents initial results associated with subjective workload ratings and group discussion feedback obtained from the experiment s commercial transport pilot participants.

  13. Profitability primer: a guide to profitability analysis in the electric power industry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Woo, C.K.; Lloyd-Zannetti, D.; Martin, J.

    1996-06-01

    As the electric power industry is opened to forces of competition, increased attention must be focused to develop products and services that deliver good value to customers and to identify customer segments that are profitable to serve. This primer introduces the concept of profitability analysis and its application to the electric power industry. The primer recognizes that some segments of the business will remain monopolistic and subject to regulations, while other segments will become competitive. The primer also recognizes that customer profitability is critically dependent on a host of related issues such as how internal costs are allocated to variousmore » functions and how revenues are collected and allocated.« less

  14. Identifying biological concepts from a protein-related corpus with a probabilistic topic model

    PubMed Central

    Zheng, Bin; McLean, David C; Lu, Xinghua

    2006-01-01

    Background Biomedical literature, e.g., MEDLINE, contains a wealth of knowledge regarding functions of proteins. Major recurring biological concepts within such text corpora represent the domains of this body of knowledge. The goal of this research is to identify the major biological topics/concepts from a corpus of protein-related MEDLINE© titles and abstracts by applying a probabilistic topic model. Results The latent Dirichlet allocation (LDA) model was applied to the corpus. Based on the Bayesian model selection, 300 major topics were extracted from the corpus. The majority of identified topics/concepts was found to be semantically coherent and most represented biological objects or concepts. The identified topics/concepts were further mapped to the controlled vocabulary of the Gene Ontology (GO) terms based on mutual information. Conclusion The major and recurring biological concepts within a collection of MEDLINE documents can be extracted by the LDA model. The identified topics/concepts provide parsimonious and semantically-enriched representation of the texts in a semantic space with reduced dimensionality and can be used to index text. PMID:16466569

  15. Conflict Resolution Automation and Pilot Situation Awareness

    NASA Technical Reports Server (NTRS)

    Dao, Arik-Quang V.; Brandt, Summer L.; Bacon, Paige; Kraut, Josh; Nguyen, Jimmy; Minakata, Katsumi; Raza, Hamzah; Rozovski, David; Johnson, Walter W.

    2010-01-01

    This study compared pilot situation awareness across three traffic management concepts. The Concepts varied in terms of the allocation of traffic avoidance responsibility between the pilot on the flight deck, the air traffic controllers, and a conflict resolution automation system. In Concept 1, the flight deck was equipped with conflict resolution tools that enable them to fully handle the responsibility of weather avoidance and maintaining separation between ownship and surrounding traffic. In Concept 2, pilots were not responsible for traffic separation, but were provided tools for weather and traffic avoidance. In Concept 3, flight deck tools allowed pilots to deviate for weather, but conflict detection tools were disabled. In this concept pilots were dependent on ground based automation for conflict detection and resolution. Situation awareness of the pilots was measured using online probes. Results showed that individual situation awareness was highest in Concept 1, where the pilots were most engaged, and lowest in Concept 3, where automation was heavily used. These findings suggest that for conflict resolution tasks, situation awareness is improved when pilots remain in the decision-making loop.

  16. Neurotoxicology of the Brain Barrier System: New Implications

    PubMed Central

    Zheng, Wei

    2014-01-01

    The concept of a barrier system in the brain has existed for nearly a century. The barrier that separates the blood from the cerebral interstitial fluid is defined as the blood-brain barrier, while the one that discontinues the circulation between the blood and cerebrospinal fluid is named the blood-cerebrospinal fluid barrier. Evidence in the past decades suggests that brain barriers are subject to toxic insults from neurotoxic chemicals circulating in blood. The aging process and some disease states render barriers more vulnerable to insults arising inside and outside the barriers. The implication of brain barriers in certain neurodegenerative diseases is compelling, although the contribution of chemical-induced barrier dysfunction in the etiology of any of these disorders remains poorly understood. This review examines what is currently understood about brain barrier systems in central nervous system disorders by focusing on chemical-induced neurotoxicities including those associated with nitrobenzenes, N-methyl-D-aspartate, cyclosporin A, pyridostigmine bromide, aluminum, lead, manganese, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, and 3-nitropropionic acid. Contemporary research questions arising from this growing understanding show enormous promises for brain researchers, toxicologists, and clinicians. PMID:11778669

  17. Tests of potential functional barriers for laminated multilayer food packages. Part I: Low molecular weight permeants.

    PubMed

    Simal-Gándara, J; Sarria-Vidal, M; Koorevaar, A; Rijk, R

    2000-08-01

    The advent of the functional barrier concept in food packaging has brought with it a requirement for fast tests of permeation through potential barrier materials. In such tests it would be convenient for both foodstuffs and materials below the functional barrier (sub-barrier materials) to be represented by standard simulants. By means of inverse gas chromatography, liquid paraffin spiked with appropriate permeants was considered as a potential simulant of sub-barrier materials based on polypropylene (PP) or similar polyolefins. Experiments were performed to characterize the kinetics of the permeation of low molecular weight model permeants (octene, toluene and isopropanol) from liquid paraffin, through a surrogate potential functional barrier (25 microns-thick oriented PP) into the food stimulants olive oil and 3% (w/v) acetic acid. These permeation results were interpreted in terms of three permeation kinetic models regarding the solubility of a particular model permeant in the post-barrier medium (i.e. the food simulant). The results obtained justify the development and evaluation of liquid sub-barrier simulants that would allow flexible yet rigorous testing of new laminated multilayer packaging materials.

  18. In search of patient characteristics that may guide empirically based treatment selection for personality disorder patients-a concept map approach.

    PubMed

    van Manen, J G; Kamphuis, J H; Goossensen, A; Timman, R; Busschbach, J J V; Verheul, R

    2012-08-01

    Using the concept map method, this study aimed to summarize and describe patient characteristics pertinent to treatment selection for patients with personality disorders (PDs). Initial patient characteristics were derived from the research literature and a survey among Dutch expert clinicians. Concept mapping is a formalized conceptualization procedure that describes the underlying cognitive structures people use in complex tasks, such as treatment allocation. Based on expert opinions of 29 Dutch clinicians, a concept map was generated that yielded eight domains of patient characteristics, i.e., Severity of symptoms, Severity of personality pathology, Ego-adaptive capacities, Motivation and working alliance, Social context, Social demographic characteristics, Trauma, and Treatment history and medical condition. These domains can be ordered along two bipolar axes, running from internal to external concepts and from vulnerability to strength concepts, respectively. Our findings may serve as input for the delineation of algorithms for patient-treatment matching research in PD.

  19. Energy allocation during the maturation of adults in a long-lived insect: implications for dispersal and reproduction.

    PubMed

    David, G; Giffard, B; van Halder, I; Piou, D; Jactel, H

    2015-10-01

    Energy allocation strategies have been widely documented in insects and were formalized in the context of the reproduction process by the terms 'capital breeder' and 'income breeder'. We propose here the extension of this framework to dispersal ability, with the concepts of 'capital disperser' and 'income disperser', and explore the trade-off in resource allocation between dispersal and reproduction. We hypothesized that flight capacity was sex-dependent, due to a trade-off in energy allocation between dispersal and egg production in females. We used Monochamus galloprovincialis as model organism, a long-lived beetle which is the European vector of the pine wood nematode. We estimated the flight capacity with a flight mill and used the number of mature eggs as a proxy for the investment in reproduction. We used the ratio between dry weights of the thorax and the abdomen to investigate the trade-off. The probability of flying increased with the adult weight at emergence, but was not dependent on insect age or sex. Flight distance increased with age in individuals but did not differ between sexes. It was also positively associated with energy allocation to thorax reserves, which increased with age. In females, the abdomen weight and the number of eggs also increase with age with no negative effect on flight capacity, indicating a lack of trade-off. This long-lived beetle has a complex strategy of energy allocation, being a 'capital disperser' in terms of flight ability, an 'income disperser' in terms of flight performance and an 'income breeder' in terms of egg production.

  20. Sustainability in health care by allocating resources effectively (SHARE) 3: examining how resource allocation decisions are made, implemented and evaluated in a local healthcare setting.

    PubMed

    Harris, Claire; Allen, Kelly; Waller, Cara; Brooke, Vanessa

    2017-05-09

    This is the third in a series of papers reporting a program of Sustainability in Health care by Allocating Resources Effectively (SHARE) in a local healthcare setting. Leaders in a large Australian health service planned to establish an organisation-wide, systematic, integrated, evidence-based approach to disinvestment. In order to introduce new systems and processes for disinvestment into existing decision-making infrastructure, we aimed to understand where, how and by whom resource allocation decisions were made, implemented and evaluated. We also sought the knowledge and experience of staff regarding previous disinvestment activities. Structured interviews, workshops and document analysis were used to collect information from multiple sources in an environmental scan of decision-making systems and processes. Findings were synthesised using a theoretical framework. Sixty-eight respondents participated in interviews and workshops. Eight components in the process of resource allocation were identified: Governance, Administration, Stakeholder engagement, Resources, Decision-making, Implementation, Evaluation and, where appropriate, Reinvestment of savings. Elements of structure and practice for each component are described and a new framework was developed to capture the relationships between them. A range of decision-makers, decision-making settings, type and scope of decisions, criteria used, and strengths, weaknesses, barriers and enablers are outlined. The term 'disinvestment' was not used in health service decision-making. Previous projects that involved removal, reduction or restriction of current practices were driven by quality and safety issues, evidence-based practice or a need to find resource savings and not by initiatives where the primary aim was to disinvest. Measuring resource savings is difficult, in some situations impossible. Savings are often only theoretical as resources released may be utilised immediately by patients waiting for beds, clinic appointments or surgery. Decision-making systems and processes for resource allocation are more complex than assumed in previous studies. There is a wide range of decision-makers, settings, scope and type of decisions, and criteria used for allocating resources within a single institution. To our knowledge, this is the first paper to report this level of detail and to introduce eight components of the resource allocation process identified within a local health service.

  1. Proceedings of the Flat-plate Solar Array Project Research Forum on High-efficiency Crystalline Silicon Solar Cells

    NASA Technical Reports Server (NTRS)

    Kachare, R.

    1985-01-01

    The high-efficiency crystalline silicon solar cells research forum addressed high-efficiency concepts, surface-interface effects, bulk effects, modeling and device processing. The topics were arranged into six interactive sessions, which focused on the state-of-the-art of device structures, identification of barriers to achieve high-efficiency cells and potential ways to overcome these barriers.

  2. Obstaculos al aprendizaje--obstaculos a la ensenanza en contextos (Barriers to Learning--Barriers to Teaching in Multicultural Contexts). Papers on Teacher Training and Multicultural/Intercultural Education 25.

    ERIC Educational Resources Information Center

    Gagliardi, Raul

    This study focused on identifying learning difficulties with a view to incorporating both understanding of those difficulties and methods for minimizing or neutralizing them in multicultural classroom settings. Discussion gives guidelines for teachers to use in analyzing student concepts and approaches to learning, particularly in the…

  3. EFFECTS OF LASER RADIATION ON MATTER. LASER PLASMA: Spatial-temporal distribution of a mechanical load resulting from interaction of laser radiation with a barrier (analytic model)

    NASA Astrophysics Data System (ADS)

    Fedyushin, B. T.

    1992-01-01

    The concepts developed earlier are used to propose a simple analytic model describing the spatial-temporal distribution of a mechanical load (pressure, impulse) resulting from interaction of laser radiation with a planar barrier surrounded by air. The correctness of the model is supported by a comparison with experimental results.

  4. The 'bankability' of the new waste technologies: an econometric method for risk sharing in private finance waste contracts.

    PubMed

    Black, I; Seaton, R; Chackiath, S; Wagland, S T; Pollard, S J T; Longhurst, P J

    2011-12-01

    The identification of risk and its appropriate allocation to partners in project consortia is essential for minimizing overall project risks, ensuring timely delivery and maximizing benefit for money invested. Risk management guidance available from government bodies, especially in the UK, does not specify methodologies for quantitative risk assessment, nor does it offer a procedure for allocating risk among project partners. Here, a methodology to quantify project risk and potential approaches to allocating risk and their implications are discussed. Construction and operation of a waste management facility through a public-private finance contract are discussed. Public-private partnership contracts are special purpose vehicle (SPV) financing methods promoted by the UK government to boost private sector investment in facilities for public service enhancement. Our findings question the appropriateness of using standard deviation as a measure for project risk and confirm the concept of portfolio theory, suggesting the pooling of risk can reduce total risk and its impact.

  5. Congestion Pricing for Aircraft Pushback Slot Allocation.

    PubMed

    Liu, Lihua; Zhang, Yaping; Liu, Lan; Xing, Zhiwei

    2017-01-01

    In order to optimize aircraft pushback management during rush hour, aircraft pushback slot allocation based on congestion pricing is explored while considering monetary compensation based on the quality of the surface operations. First, the concept of the "external cost of surface congestion" is proposed, and a quantitative study on the external cost is performed. Then, an aircraft pushback slot allocation model for minimizing the total surface cost is established. An improved discrete differential evolution algorithm is also designed. Finally, a simulation is performed on Xinzheng International Airport using the proposed model. By comparing the pushback slot control strategy based on congestion pricing with other strategies, the advantages of the proposed model and algorithm are highlighted. In addition to reducing delays and optimizing the delay distribution, the model and algorithm are better suited for use for actual aircraft pushback management during rush hour. Further, it is also observed they do not result in significant increases in the surface cost. These results confirm the effectiveness and suitability of the proposed model and algorithm.

  6. Congestion Pricing for Aircraft Pushback Slot Allocation

    PubMed Central

    Zhang, Yaping

    2017-01-01

    In order to optimize aircraft pushback management during rush hour, aircraft pushback slot allocation based on congestion pricing is explored while considering monetary compensation based on the quality of the surface operations. First, the concept of the “external cost of surface congestion” is proposed, and a quantitative study on the external cost is performed. Then, an aircraft pushback slot allocation model for minimizing the total surface cost is established. An improved discrete differential evolution algorithm is also designed. Finally, a simulation is performed on Xinzheng International Airport using the proposed model. By comparing the pushback slot control strategy based on congestion pricing with other strategies, the advantages of the proposed model and algorithm are highlighted. In addition to reducing delays and optimizing the delay distribution, the model and algorithm are better suited for use for actual aircraft pushback management during rush hour. Further, it is also observed they do not result in significant increases in the surface cost. These results confirm the effectiveness and suitability of the proposed model and algorithm. PMID:28114429

  7. Functional Allocation for Ground-Based Automated Separation Assurance in NextGen

    NASA Technical Reports Server (NTRS)

    Prevot, Thomas; Mercer, Joey; Martin, Lynne; Homola, Jeffrey; Cabrall, Christopher; Brasil, Connie

    2010-01-01

    As part of an ongoing research effort into functional allocation in a NextGen environment, a controller-in-the-loop study on ground-based automated separation assurance was conducted at NASA Ames' Airspace Operations Laboratory in February 2010. Participants included six FAA front line managers, who are currently certified professional controllers and four recently retired controllers. Traffic scenarios were 15 and 30 minutes long where controllers interacted with advanced technologies for ground-based separation assurance, weather avoidance, and arrival metering. The automation managed the separation by resolving conflicts automatically and involved controllers only by exception, e.g., when the automated resolution would have been outside preset limits. Results from data analyses show that workload was low despite high levels of traffic, Operational Errors did occur but were closely tied to local complexity, and safety acceptability ratings varied with traffic levels. Positive feedback was elicited for the overall concept with discussion on the proper allocation of functions and trust in automation.

  8. Cooperative institutions for sustainable common pool resource management: Application to groundwater

    NASA Astrophysics Data System (ADS)

    Madani, Kaveh; Dinar, Ariel

    2012-09-01

    Beneficiaries of common pool resources (CPRs) may select available noncooperative and regulatory exogenous institutions for managing the resource, as well as cooperative management institutions. All these institutions may increase the long-term gains, prolong the life of the resource, and help to escape the tragedy of the commons trap. Cooperative game theory approaches can serve as the backbone of cooperative CPR management institutions. This paper formulates and applies several commonly used cooperative game theoretic solution concepts, namely, the core, Nash-Harsanyi, Shapley, and nucleolus. Through a numerical groundwater example, we show how CPR users can share the gains obtained from cooperation in a fair and efficient manner based on these cooperative solution concepts (management institutions). Although, based on their fairness rationales, various cooperative management institutions may suggest different allocations that are potentially acceptable to the users, these allocation solutions may not be stable as some users may find them unfair. This paper discusses how different methods, such as application of the plurality rule and power index, stability index, and propensity to disrupt concepts, can help identify the most stable and likely solutions for enforcing cooperation among the CPR beneficiaries. Furthermore, how the noncooperative managerial characteristics of the CPR users can affect the stability and acceptability of the different cooperative CPR management institutions is discussed, providing valuable policy insights for cooperative CPR management at community levels.

  9. Material Barriers to Diffusive Mixing

    NASA Astrophysics Data System (ADS)

    Haller, George; Karrasch, Daniel

    2017-11-01

    Transport barriers, as zero-flux surfaces, are ill-defined in purely advective mixing in which the flux of any passive scalar is zero through all material surfaces. For this reason, Lagrangian Coherent Structures (LCSs) have been argued to play the role of mixing barriers as most repelling, attracting or shearing material lines. These three kinematic concepts, however, can also be defined in different ways, both within rigorous mathematical treatments and within the realm of heuristic diagnostics. This has lead to a an ever-growing number of different LCS methods, each generally identifying different objects as transport barriers. In this talk, we examine which of these methods have actual relevance for diffusive transport barriers. The latter barriers are arguably the practically relevant inhibitors in the mixing of physically relevant tracers, such as temperature, salinity, vorticity or potential vorticity. We demonstrate the role of the most effective diffusion barriers in analytical examples and observational data. Supported in part by the DFG Priority Program on Turbulent Superstructures.

  10. Effective Results of an Open Concept School

    ERIC Educational Resources Information Center

    Cobos, Irma; Lewallen, Joy

    2009-01-01

    Open concept schools were a popular architectural design in the 70s. They were built to provide large areas of flexible space for team teaching with small enclosed areas for restrooms, science labs, and special needs classrooms. Because there are no barriers and no closed doors, an attitude of inclusiveness is created merely by the building's…

  11. Open Ends and Means: Inquiry as a Link between Formal Music Concepts and Informal Music Learning

    ERIC Educational Resources Information Center

    Schmidt-Jones, Catherine Anne

    2017-01-01

    There is currently considerable interest in strengthening the connections between formal music education and informal, self-motivated music practices. Participants in this study were adults who were self-motivated to learn formal music concepts, but had encountered barriers to doing so independently. The study offered them individual online…

  12. A Group Decision Approach to Developing Concept-Effect Models for Diagnosing Student Learning Problems in Mathematics

    ERIC Educational Resources Information Center

    Hwang, Gwo-Jen; Panjaburee, Patcharin; Triampo, Wannapong; Shih, Bo-Ying

    2013-01-01

    Diagnosing student learning barriers has been recognized as the most fundamental and important issue for improving the learning achievements of students. In the past decade, several learning diagnosis approaches have been proposed based on the concept-effect relationship (CER) model. However, past studies have shown that the effectiveness of this…

  13. Must a Developed Democratic State Fully Resource Any Tertiary Education for Its Citizens?

    ERIC Educational Resources Information Center

    Scholes, Vanessa

    2014-01-01

    This article takes a parsimonious conception of a developed State operating under a minimalist conception of democracy and asks whether such a State must fully resource any tertiary (post-compulsory) education for its citizens A key public policy barrier to arguing an absolute obligation for the State to resource any tertiary education is…

  14. Cross-Cultural Barriers to Effective Communication in Aviation

    NASA Technical Reports Server (NTRS)

    Orasanu, Judith; Davison, Jeannie; Shafto, Michael G. (Technical Monitor)

    1995-01-01

    Recent research on communication and performance in airline flight crews has led to a concept of shared mental models that is associated with effective, efficient team coordination in problem solving and decision making situations. Elements that characterize efficient communication have been identified. This research, however, was based strictly on US crews. More recent studies supported by NASA have identified cultural factors that influence communication among team members who vary in their status and roles. Research is just beginning to identify commonalities and culturally distinct strategies for accomplishing joint tasks. ASRS incident reports have been analyzed to identify language barriers in flight that have safety consequences. Implications of these concepts and findings for multi-cultural command and control will be explored.

  15. A Survey of Challenges in Aerodynamic Exhaust Nozzle Technology for Aerospace Propulsion Applications

    NASA Technical Reports Server (NTRS)

    Shyne, Rickey J.

    2002-01-01

    The current paper discusses aerodynamic exhaust nozzle technology challenges for aircraft and space propulsion systems. Technology advances in computational and experimental methods have led to more accurate design and analysis tools, but many major challenges continue to exist in nozzle performance, jet noise and weight reduction. New generations of aircraft and space vehicle concepts dictate that exhaust nozzles have optimum performance, low weight and acceptable noise signatures. Numerous innovative nozzle concepts have been proposed for advanced subsonic, supersonic and hypersonic vehicle configurations such as ejector, mixer-ejector, plug, single expansion ramp, altitude compensating, lobed and chevron nozzles. This paper will discuss the technology barriers that exist for exhaust nozzles as well as current research efforts in place to address the barriers.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huff, Kathryn D.

    Component level and system level abstraction of detailed computational geologic repository models have resulted in four rapid computational models of hydrologic radionuclide transport at varying levels of detail. Those models are described, as is their implementation in Cyder, a software library of interchangeable radionuclide transport models appropriate for representing natural and engineered barrier components of generic geology repository concepts. A proof of principle demonstration was also conducted in which these models were used to represent the natural and engineered barrier components of a repository concept in a reducing, homogenous, generic geology. This base case demonstrates integration of the Cyder openmore » source library with the Cyclus computational fuel cycle systems analysis platform to facilitate calculation of repository performance metrics with respect to fuel cycle choices. (authors)« less

  17. Stored Carbon Dynamics are Controlled by a Combination of Evolutionary, Physiological, and Ecological Pressures

    NASA Astrophysics Data System (ADS)

    Aubrey, D. P.; Mims, J. T.; Oswald, S. W.; Teskey, R. O.; Mitchell, R. J.

    2016-12-01

    Allocation of assimilated carbon to storage provides a critical carbohydrate buffer when metabolic demands exceed current photosynthetic supply; however, our process-level understanding of controls on carbon storage pools and fluxes remains relatively poor. Recent studies have shifted the paradigm from the concept that stored carbon pools are a sink of low priority that accumulate passively when photosynthetic inputs exceed demand toward the concept that these pools are active sinks of high priority. It follows that allocation toward storage—at the expense of growth—is a trait that would be under selective pressure since species that allocate toward storage should be more resilient to disturbance. Using fire-dependent longleaf pine in a series of manipulative and observational studies, we explore how stored carbon dynamics are controlled by a combination of evolutionary, physiological, and ecological pressures. Our manipulative studies revealed large stored carbon pools in roots that maintained belowground metabolism for a year after current photosynthetic supply was restricted. Likewise, the concentration of stored carbon in the smallest, most metabolically active roots was not influenced until nearly one year later. Our observational studies indicated that stored carbon pools differ among closely related species with overlapping natural distributions, but evolutionary histories of different disturbance frequencies and thus, different selective pressures on carbon storage. Our comparisons of stored carbon pools between longleaf trees growing under xeric or mesic soil moisture regimes indicated that allocation toward storage exhibits plasticity through space and time in response to both short- and long-term variations in resource availability. We expect a continuum of responses to disturbances related to ecological niche and evolutionary adaptation that influence the availability of carbohydrates for metabolic demands. We also expect a continuum in stored carbon pools and metabolic buffering capacity among species as well as spatially, temporally, and developmentally within individual species.

  18. Patients' Perceptions of an Exercise Program Delivered Following Discharge From Hospital After Critical Illness (the Revive Trial).

    PubMed

    Ferguson, Kathryn; Bradley, Judy M; McAuley, Daniel F; Blackwood, Bronagh; O'Neill, Brenda

    2017-01-01

    The REVIVE randomized controlled trial (RCT) investigated the effectiveness of an individually tailored (personalized) exercise program for patients discharged from hospital after critical illness. By including qualitative methods, we aimed to explore patients' perceptions of engaging in the exercise program. Patients were recruited from general intensive care units in 6 hospitals in Northern Ireland. Patients allocated to the exercise intervention group were invited to participate in this qualitative study. Independent semistructured interviews were conducted at 6 months after randomization. Interviews were audio-recorded, transcribed, and content analysis used to explore themes arising from the data. Of 30 patients allocated to the exercise group, 21 completed the interviews. Patients provided insight into the physical and mental sequelae they experienced following critical illness. There was a strong sense of patients' need for the exercise program and its importance for their recovery following discharge home. Key facilitators of the intervention included supervision, tailoring of the exercises to personal needs, and the exercise manual. Barriers included poor mental health, existing physical limitations, and lack of motivation. Patients' views of outcome measures in the REVIVE RCT varied. Many patients were unsure about what would be the best way of measuring how the program affected their health. This qualitative study adds an important perspective on patients' attitude to an exercise intervention following recovery from critical illness, and provides insight into the potential facilitators and barriers to delivery of the program and how programs should be evolved for future trials.

  19. Barriers to accessing adequate maternal care in Central and Eastern European countries: A systematic literature review.

    PubMed

    Miteniece, Elina; Pavlova, Milena; Rechel, Bernd; Groot, Wim

    2017-03-01

    Maternal health outcomes in Central and Eastern Europe (CEE) compare unfavorable with those in Western Europe, despite macro-indicators that suggest well-designed maternal care systems. However, macro-indicators at the system level only capture capacity, funding and utilization of care and not the actual allocation of financial and human resources, the quality of care and access to it. It is these latter which are problematic in the CEE region. In this study service-related indicators of access to maternal care in CEE are examined. These include availability, appropriateness, affordability, approachability and acceptability of maternal care. This study uses a qualitative systematic literature review, analyzing information of peer-reviewed articles published since 2004. Other inclusion criteria included language, setting and publication purpose. The included articles were analyzed using a framework analysis technique and quality was assessed using standardized evaluation checklists. Results indicate improvements in maternal care. However, availability of care is limited by outdated equipment and training curricula, and the lack of professionals and pharmaceuticals. Geographical distance to healthcare institutions, inappropriate communication of providers and waiting times are the main approachability barriers. Some mothers are unaware of the importance of care or are discouraged to utilize healthcare services because of cultural aspects. Finally, a major barrier in accessing maternal care in the CEE is the inability to pay for it. Our findings indicate that major gaps in evidence exist and that more representative and better quality data should be collected. Governments in CEE countries need to establish a reliable system for measuring and monitoring a suitable set of indicators, as well as deal with the general social and economic problem of informality. Medical curricula in the CEE region need to be overhauled and there should be a focus on improving the allocation of medical staff and institutions as well as protecting vulnerable population groups to ensure universal access to care. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. A Concept for Run-Time Support of the Chapel Language

    NASA Technical Reports Server (NTRS)

    James, Mark

    2006-01-01

    A document presents a concept for run-time implementation of other concepts embodied in the Chapel programming language. (Now undergoing development, Chapel is intended to become a standard language for parallel computing that would surpass older such languages in both computational performance in the efficiency with which pre-existing code can be reused and new code written.) The aforementioned other concepts are those of distributions, domains, allocations, and access, as defined in a separate document called "A Semantic Framework for Domains and Distributions in Chapel" and linked to a language specification defined in another separate document called "Chapel Specification 0.3." The concept presented in the instant report is recognition that a data domain that was invented for Chapel offers a novel approach to distributing and processing data in a massively parallel environment. The concept is offered as a starting point for development of working descriptions of functions and data structures that would be necessary to implement interfaces to a compiler for transforming the aforementioned other concepts from their representations in Chapel source code to their run-time implementations.

  1. Strategic Alliances in Education: The Knowledge Engineering Web

    ERIC Educational Resources Information Center

    Westera, Wim; van den Herik, Jaap; van de Vrie, Evert

    2004-01-01

    The field of higher education shows a jumble of alliances between fellow institutes. The alliances are strategic in kind and serve an economy-of-scales concept. A large scale is a prerequisite for allocating the budgets for new educational methods and technologies in order to keep the educational services up-to-date. All too often, however,…

  2. National Training Course. Emergency Medical Technician. Paramedic. Instructor's Lesson Plans. Module XV. Telemetry and Communications.

    ERIC Educational Resources Information Center

    National Highway Traffic Safety Administration (DOT), Washington, DC.

    This instructor's lesson plan guide on telemetry and communications is one of fifteen modules designed for use in the training of emergency medical technicians (paramedics). Two units of study are presented: (1) emergency medical services communications systems (items of equipment and such radio communications concepts as frequency allocation,…

  3. Understanding Corporate Sponsorships: Moving from a $100 Ad Purchase to a $1,000 Sponsorship Agreement

    ERIC Educational Resources Information Center

    Hatfield, Laura M.; Hatfield, Lance C.

    2014-01-01

    A corporate sponsorship program, built on an appropriate knowledge base, can help bridge the funding gap that exists in interscholastic athletics between the cost of fielding teams and decreasing budget allocations. This article describes sponsorship in its most effective form as a business concept, the value that athletic departments provide to…

  4. The Child Day Care Recycling Fund Experiment: The Waiting List Analysis.

    ERIC Educational Resources Information Center

    Bowen, Gary L.; And Others

    The Recycling Fund Concept was conceptualized as a special allocation of money for the purpose of expanding child care services for preschool children of low-income parents who were or had been recipients of Aid to Families with Dependent Children in Mecklenburg County, North Carolina. In 1985, North Carolina's Child Care Resources Incorporated…

  5. The role of the landscape architect in applied forest landscape management: a case study on process

    Treesearch

    Wayne Tlusty

    1979-01-01

    Land planning allocations are often multi-resource concepts, with visual quality objectives addressing the appropriate level of visual resource management. Current legislation and/or regulations often require interdisciplinary teams to implement planning decisions. A considerable amount of information is currently avail-able on visual assessment techniques both for...

  6. Structural Framework for Flight: NASA's Role in Development of Advanced Composite Materials for Aircraft and Space Structures

    NASA Technical Reports Server (NTRS)

    Tenney, Darrel R.; Davis, John G., Jr.; Johnston, Norman J.; Pipes, R. Byron; McGuire, Jack F.

    2011-01-01

    This serves as a source of collated information on Composite Research over the past four decades at NASA Langley Research Center, and is a key reference for readers wishing to grasp the underlying principles and challenges associated with developing and applying advanced composite materials to new aerospace vehicle concepts. Second, it identifies the major obstacles encountered in developing and applying composites on advanced flight vehicles, as well as lessons learned in overcoming these obstacles. Third, it points out current barriers and challenges to further application of composites on future vehicles. This is extremely valuable for steering research in the future, when new breakthroughs in materials or processing science may eliminate/minimize some of the barriers that have traditionally blocked the expanded application of composite to new structural or revolutionary vehicle concepts. Finally, a review of past work and identification of future challenges will hopefully inspire new research opportunities and development of revolutionary materials and structural concepts to revolutionize future flight vehicles.

  7. Investigation of a New Concept in Semiconductor Microwave Oscillators: The Contiguous Domain Oscillator

    DTIC Science & Technology

    1993-02-28

    on a potential microwave source with many novel properties. It combines the transferred electron effect in n-type GaAs material together with 2 the...the channel direction. This barrier could be a physical barrier provided by a high band-gap material in a MOSFET structure or a potential barrier...rralivtic vcloocltv flc’ld curve of GmAs\\. chargc- oscillation ii po, ~ible once the dectnic fiC Xi di ’!I;ihU1]0n ClC(I OceCd OheMO) Osld fticl, ’Idh in 3

  8. Wings: A New Paradigm in Human-Centered Design

    NASA Technical Reports Server (NTRS)

    Schutte, Paul C.

    1997-01-01

    Many aircraft accidents/incidents investigations cite crew error as a causal factor (Boeing Commercial Airplane Group 1996). Human factors experts suggest that crew error has many underlying causes and should be the start of an accident investigation and not the end. One of those causes, the flight deck design, is correctable. If a flight deck design does not accommodate the human's unique abilities and deficits, crew error may simply be the manifestation of this mismatch. Pilots repeatedly report that they are "behind the aircraft" , i.e., they do not know what the automated aircraft is doing or how the aircraft is doing it until after the fact. Billings (1991) promotes the concept of "human-centered automation"; calling on designers to allocate appropriate control and information to the human. However, there is much ambiguity regarding what it mean's to be human-centered. What often are labeled as "human-centered designs" are actually designs where a human factors expert has been involved in the design process or designs where tests have shown that humans can operate them. While such designs may be excellent, they do not represent designs that are systematically produced according to some set of prescribed methods and procedures. This paper describes a design concept, called Wings, that offers a clearer definition for human-centered design. This new design concept is radically different from current design processes in that the design begins with the human and uses the human body as a metaphor for designing the aircraft. This is not because the human is the most important part of the aircraft (certainly the aircraft would be useless without lift and thrust), but because he is the least understood, the least programmable, and one of the more critical elements. The Wings design concept has three properties: a reversal in the design process, from aerodynamics-, structures-, and propulsion-centered to truly human-centered; a design metaphor that guides function allocation and control and display design; and a deliberate distinction between two fundamental functions of design, to complement and to interpret human performance. The complementary function extends the human's capabilities beyond his or her current limitations - this includes sensing, computation, memory, physical force, and human decision making styles and skills. The interpretive (or hermeneutic, Hollnagel 1991) function translates information, functionality, and commands between the human and the aircraft. The Wings design concept allows the human to remain aware of the aircraft through natural interpretation. It also affords great improvements in system performance by maximizing the human's natural abilities and complementing the human's skills in a natural way. This paper will discuss the Wings design concept by describing the reversal in the traditional design process, the function allocation strategy of Wings, and the functions of complementing and interpreting the human.

  9. River channel morphology and hydraulics properties due to introduction of plant basket hydraulic structures for river channel management

    NASA Astrophysics Data System (ADS)

    Kałuża, Tomasz; Radecki-Pawlik, Artur; Plesiński, Karol; Walczak, Natalia; Szoszkiewicz, Krzysztof; Radecki-Pawlik, Bartosz

    2016-04-01

    In the present time integrated water management is directly connected with management and direct works in river channels themselves which are taking into account morphological processes in rivers and improve flow conditions. Our work focused on the hydraulic and hydrodynamic consequences upon the introduction of the concept of the improvement of the hydromorphological conditions of the Flinta River in a given reach following river channel management concept. Based on a comprehensive study of the hydromorphological state of the river, four sections were selected where restoration measures can efficiently improve river habitat conditions in the river. For each section a set of technical and biological measures were proposed and implemented in practice. One of the proposed solutions was to construct plant basket hydraulic structures (PBHS) within the river channel, which are essentially plant barriers working as sediment traps, changing river channel morphology and are in line with concepts of Water Framework Directive. These relatively small structures work as crested weirs and unquestionably change the channel morphology. Along our work we show the results of three-year long (2013-2015) systematic measurements that provided information on the morphological consequences of introducing such structures into a river channel. Our main conclusions are as follows: 1. Plant basket hydraulic structures cause changes in hydrodynamic conditions and result in sediment accumulation and the formation of river backwaters upstream and downstream the obstacle; 2. The introduced plant basket hydraulic structures cause plant debris accumulation which influences the hydrodynamic flow conditions; 3. The installation of plant basket hydraulic structures on the river bed changes flow pattern as well as flow hydrodynamic conditions causing river braiding process; 4. The erosion rate below the plant basket hydraulic structures is due to the hydraulic work conditions of the PBHS and its calculated value was confirmed by direct measurements in the field. In our calculations we used VCmaster software. This Work funded by the National Science Centre allocated based on the number of decision: DEC-2011/01 / B / ST10 / 06959

  10. The "ick" factor, anticipated regret, and willingness to become an organ donor.

    PubMed

    O'Carroll, Ronan E; Foster, Catherine; McGeechan, Grant; Sandford, Kayleigh; Ferguson, Eamonn

    2011-03-01

    This research tested the role of traditional rational-cognitive factors and emotional barriers to posthumous organ donation. An example of an emotional barrier is the "ick" factor, a basic disgust reaction to the idea of organ donation. We also tested the potential role of manipulating anticipated regret to increase intention to donate in people who are not yet registered organ donors. In three experiments involving 621 members of the United Kingdom general public, participants were invited to complete questionnaire measures tapping potential emotional affective attitude barriers such as the "ick" factor, the desire to retain bodily integrity after death, and medical mistrust. Registered posthumous organ donors were compared with nondonors. In Experiments 2 and 3, nondonors were then allocated to a simple anticipated regret manipulation versus a control condition, and the impact on intention to donate was tested. Self-reported emotional barriers and intention to donate in the future. Traditional rational-cognitive factors such as knowledge, attitude, and subjective norm failed to distinguish donors from nondonors. However, in all three experiments, nondonors scored significantly higher than donors on the emotional "ick" factor and bodily integrity scales. A simple anticipated regret manipulation led to a significant increase in intention to register as an organ donor in future. Negative affective attitudes are thus crucial barriers to people registering as organ donors. A simple anticipated regret manipulation has the potential to significantly increase organ donation rates. (c) 2011 APA, all rights reserved

  11. Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

    PubMed Central

    Kelly, John R.; Kennedy, Paul J.; Cryan, John F.; Dinan, Timothy G.; Clarke, Gerard; Hyland, Niall P.

    2015-01-01

    The emerging links between our gut microbiome and the central nervous system (CNS) are regarded as a paradigm shift in neuroscience with possible implications for not only understanding the pathophysiology of stress-related psychiatric disorders, but also their treatment. Thus the gut microbiome and its influence on host barrier function is positioned to be a critical node within the brain-gut axis. Mounting preclinical evidence broadly suggests that the gut microbiota can modulate brain development, function and behavior by immune, endocrine and neural pathways of the brain-gut-microbiota axis. Detailed mechanistic insights explaining these specific interactions are currently underdeveloped. However, the concept that a “leaky gut” may facilitate communication between the microbiota and these key signaling pathways has gained traction. Deficits in intestinal permeability may underpin the chronic low-grade inflammation observed in disorders such as depression and the gut microbiome plays a critical role in regulating intestinal permeability. In this review we will discuss the possible role played by the gut microbiota in maintaining intestinal barrier function and the CNS consequences when it becomes disrupted. We will draw on both clinical and preclinical evidence to support this concept as well as the key features of the gut microbiota which are necessary for normal intestinal barrier function. PMID:26528128

  12. Concept identification for a power take-off shielding campaign.

    PubMed

    Tinc, P J; Madden, E; Park, S; Weil, R; Sorensen, J A

    2015-01-01

    ABSTRACT Machinery entanglements, specifically power take-off (PTO) entanglements, are a leading cause of injuries and fatalities on farms. In order to address this life-threatening issue, a social marketing campaign is being developed to reduce barriers and emphasize motivators to shielding. This article discusses the process of designing, testing, and selecting concepts to be used in the campaign. Small-group discussions (triads) were held to test 13 message concepts. Participants were asked to provide feedback and select the two messages that they believed to be most powerful. Upon completion, three message concepts were selected to be finalized.

  13. Organizing uninsured safety-net access to specialist physician services.

    PubMed

    Hall, Mark A

    2013-05-01

    Arranging referrals for specialist services is often the greatest difficulty that safety-net access programs face in attempting to provide fairly comprehensive services for the uninsured. When office-based community specialists are asked to care for uninsured patients, they cite the following barriers: difficulty determining which patients merit charity care, having to arrange for services patients need from other providers, and concerns about liability for providing inadequate care. Solutions to these barriers to specialist access can be found in the same institutional arrangements that support primary care and hospital services for the uninsured. These safety-net organization structures can be extended to include specialist physician care by funding community health centers to contract for specialist referrals, using free-standing referral programs to subsidize community specialists who accept uninsured patients at discounted rates, and encouraging hospitals through tax exemption or disproportionate share funding to require specialists on their medical staffs to accept an allocation of uninsured office-based referrals.

  14. Safety Challenges and Improvement Strategies of Ethnic Minority Construction Workers: A Case Study in Hong Kong.

    PubMed

    Wu, Chunlin; Luo, Xiaowei; Wang, Tao; Wang, Yue; Sapkota, Bibek

    2018-04-18

    Due to cultural differences, ethnic minority construction workers are more difficult to manage and more vulnerable to accidents. This study aims to identify the major barriers faced by ethnic minority workers from their own perspectives and determine potential strategies to enhance safety climate of construction projects, thus ultimately improve their safety performance. A survey with modified Nordic safety climate questionnaire was conducted in a certain sub-contractor in Hong Kong. In-depth interviews, status quo description, major challenge investigation and safety knowledge tests were carried as well. The top three most important safety challenges identified are improper stereotypes from the whole industry, lack of opportunities for job assignment, and language barriers. To improve the safety performance, employers should allocate sufficient personal protective equipment and governments should organize unannounced site visits more frequently. Besides, the higher-level management should avoid giving contradictory instructions to foremen against to the standards of supervisors.

  15. Portfolio evaluation of health programs: a reply to Sendi et al.

    PubMed

    Bridges, John F P; Terris, Darcey D

    2004-05-01

    Sendi et al. (Soc. Sci. Med. 57 (2003) 2207) extend previous research on cost-effectiveness analysis to the evaluation of a portfolio of interventions with risky outcomes using a "second best" approach that can identify improvements in efficiency in the allocation of resources. This method, however, cannot be used to directly identify the optimal solution to the resource allocation problem. Theoretically, a stricter adherence to the foundations of portfolio theory would permit direct optimization in portfolio selection, however, when we include uncertainty in our analysis in addition to the traditional concept of risk (which is often mislabelled uncertainty) complexities are introduced that create significant hurdles in the development of practical applications of portfolio theory for health care policy decision making.

  16. Statistical mechanics of competitive resource allocation using agent-based models

    NASA Astrophysics Data System (ADS)

    Chakraborti, Anirban; Challet, Damien; Chatterjee, Arnab; Marsili, Matteo; Zhang, Yi-Cheng; Chakrabarti, Bikas K.

    2015-01-01

    Demand outstrips available resources in most situations, which gives rise to competition, interaction and learning. In this article, we review a broad spectrum of multi-agent models of competition (El Farol Bar problem, Minority Game, Kolkata Paise Restaurant problem, Stable marriage problem, Parking space problem and others) and the methods used to understand them analytically. We emphasize the power of concepts and tools from statistical mechanics to understand and explain fully collective phenomena such as phase transitions and long memory, and the mapping between agent heterogeneity and physical disorder. As these methods can be applied to any large-scale model of competitive resource allocation made up of heterogeneous adaptive agent with non-linear interaction, they provide a prospective unifying paradigm for many scientific disciplines.

  17. Sustainability in Health care by allocating resources effectively (SHARE) 1: introducing a series of papers reporting an investigation of disinvestment in a local healthcare setting.

    PubMed

    Harris, Claire; Green, Sally; Ramsey, Wayne; Allen, Kelly; King, Richard

    2017-05-04

    This is the first in a series of papers reporting Sustainability in Health care by Allocating Resources Effectively (SHARE). The SHARE Program is an investigation of concepts, opportunities, methods and implications for evidence-based investment and disinvestment in health technologies and clinical practices in a local healthcare setting. The papers in this series are targeted at clinicians, managers, policy makers, health service researchers and implementation scientists working in this context. This paper presents an overview of the organisation-wide, systematic, integrated, evidence-based approach taken by one Australian healthcare network and provides an introduction and guide to the suite of papers reporting the experiences and outcomes.

  18. SNS Heterojunctions With New Combinations Of Materials

    NASA Technical Reports Server (NTRS)

    Vasquez, Richard P.; Hunt, Brian D.; Foote, Marc C.

    1992-01-01

    New combinations of materials proposed for superconductor/normal-metal/superconductor (SNS) heterojunctions in low-temperature electronic devices such as fast switches, magnetometers, and mixers. Epitaxial heterojunctions formed between high-temperature superconductors and either oxide semiconductors or metals. Concept offers alternative to other three-layer heterojunction concepts; physical principles of operation permit SNS devices to have thicker barrier layers and fabricated more easily.

  19. Thinking of God moves attention.

    PubMed

    Chasteen, Alison L; Burdzy, Donna C; Pratt, Jay

    2010-01-01

    The concepts of God and Devil are well known across many cultures and religions, and often involve spatial metaphors, but it is not well known if our mental representations of these concepts affect visual cognition. To examine if exposure to divine concepts produces shifts of attention, participants completed a target detection task in which they were first presented with God- and Devil-related words. We found faster RTs when targets appeared at compatible locations with the concepts of God (up/right locations) or Devil (down/left locations), and also found that these results do not vary by participants' religiosity. These results indicate that metaphors associated with the divine have strong spatial components that can produce shifts of attention, and add to the growing evidence for an extremely robust connection between internal spatial representations and where attention is allocated in the external environment. 2009 Elsevier Ltd. All rights reserved.

  20. Power-efficient distributed resource allocation under goodput QoS constraints for heterogeneous networks

    NASA Astrophysics Data System (ADS)

    Andreotti, Riccardo; Del Fiorentino, Paolo; Giannetti, Filippo; Lottici, Vincenzo

    2016-12-01

    This work proposes a distributed resource allocation (RA) algorithm for packet bit-interleaved coded OFDM transmissions in the uplink of heterogeneous networks (HetNets), characterized by small cells deployed over a macrocell area and sharing the same band. Every user allocates its transmission resources, i.e., bits per active subcarrier, coding rate, and power per subcarrier, to minimize the power consumption while both guaranteeing a target quality of service (QoS) and accounting for the interference inflicted by other users transmitting over the same band. The QoS consists of the number of information bits delivered in error-free packets per unit of time, or goodput (GP), estimated at the transmitter by resorting to an efficient effective SNR mapping technique. First, the RA problem is solved in the point-to-point case, thus deriving an approximate yet accurate closed-form expression for the power allocation (PA). Then, the interference-limited HetNet case is examined, where the RA problem is described as a non-cooperative game, providing a solution in terms of generalized Nash equilibrium. Thanks to the closed-form of the PA, the solution analysis is based on the best response concept. Hence, sufficient conditions for existence and uniqueness of the solution are analytically derived, along with a distributed algorithm capable of reaching the game equilibrium.

  1. Understanding the complex interplay of barriers to physical activity amongst black and minority ethnic groups in the United Kingdom: a qualitative synthesis using meta-ethnography.

    PubMed

    Koshoedo, Sejlo A; Paul-Ebhohimhen, Virginia A; Jepson, Ruth G; Watson, Margaret C

    2015-07-12

    To conduct a meta-ethnographic analysis of qualitative studies to identify barriers to Black and Minority Ethnic (BME) individuals engaging in physical activity in the UK context. A qualitative synthesis using meta-ethnographic methods to synthesis studies of barriers to engaging in physical activity among BME groups in the UK. A comprehensive search strategy of multiple databases was employed to identify qualitative research studies published up to October 2012. The eleven searched databases included ASSIA, MEDLINE, EMBASE, CINAHL, Health Technology Assessment (HTA), NHS Scotland Library, Physical Activity Health Alliance (PAHA), PsyINFO, Social Services Abstract, Sport discuss and Web of Science. The Noblit and Hare's meta-ethnographic approach was undertaken to develop an inductive and interpretive form of knowledge synthesis. Fourteen papers met the inclusion criteria. The synthesis indicated that barriers to physical activity among BME individuals were influenced by four main concepts: perceptions; cultural expectations; personal barriers; and factors limiting access to facilities. BME individuals had different understandings of physical activity were influenced by migration history, experiences, cultural and health beliefs. This in turn may have a disempowering effect on BME individuals in terms of adopting or maintaining physical activity. These barriers to physical activity were explained at a higher conceptual level by a socio-ecological model. The social construct 'individual perception and understanding of physical activity' was particularly relevant to theoretical models and interventions. Interventions to promote engagement with physical activity need to address perceptions of this behaviour. The elicited concepts and contexts could be used to enhance the development of tailored effective health promotion interventions for BME individuals.

  2. Starting a new conversation: Engaging Veterans with spinal cord injury in discussions of what function means to them, the barriers/facilitators they encounter, and the adaptations they use to optimize function.

    PubMed

    Hill, Jennifer N; Balbale, Salva; Lones, Keshonna; LaVela, Sherri L

    2017-01-01

    Assessments of function in persons with spinal cord injury (SCI) often utilize pre-defined constructs and measures without consideration of patient context, including how patients define function and what matters to them. We utilized photovoice to understand how individuals define function, facilitators and barriers to function, and adaptations to support functioning. Veterans with SCI were provided with cameras and guidelines to take photographs of things that: (1) help with functioning, (2) are barriers to function, and (3) represent adaptations used to support functioning. Interviews to discuss photographs followed and were audio-recorded, transcribed, and analyzed using grounded-thematic coding. Nvivo 8 was used to store and organize data. Participants (n = 9) were male (89%), Caucasian (67%), had paraplegia (75%), averaged 64 years of age, and were injured, on average, for 22 years. Function was described in several ways: the concept of 'normalcy,' aspects of daily living, and ability to be independent. Facilitators included: helpful tools, physical therapy/therapists, transportation, and caregivers. Barriers included: wheelchair-related issues and interior/exterior barriers both in the community and in the hospital. Examples of adaptations included: traditional examples like ramps, and also creative examples like the use of rubber bands on a can to help with grip. Patient-perspectives elicited in-depth information that expanded the common definition of function by highlighting the concept of "normality," facilitators and barriers to function, and adaptations to optimize function. These insights emphasize function within a patient-context, emphasizing a holistic definition of function that can be used to develop personalized, patient-driven care plans. Published by Elsevier Inc.

  3. The effect of biogeographic and phylogeographic barriers on gene flow in the brown smoothhound shark, Mustelus henlei, in the northeastern Pacific

    PubMed Central

    Chabot, Chris L; Espinoza, Mario; Mascareñas-Osorio, Ismael; Rocha-Olivares, Axayácatl

    2015-01-01

    We assessed the effects of the prominent biogeographic (Point Conception and the Peninsula of Baja California) and phylogeographic barriers (Los Angeles Region) of the northeastern Pacific on the population connectivity of the brown smoothhound shark, Mustelus henlei (Triakidae). Data from the mitochondrial control region and six nuclear microsatellite loci revealed significant population structure among three populations: northern (San Francisco), central (Santa Barbara, Santa Catalina, Punta Lobos, and San Felipe), and southern (Costa Rica). Patterns of long-term and contemporary migration were incongruent, with long-term migration being asymmetric and occurring in a north to south direction and a lack of significant contemporary migration observed between localities with the exception of Punta Lobos that contributed migrants to all localities within the central population. Our findings indicate that Point Conception may be restricting gene flow between the northern and central populations whereas barriers to gene flow within the central population would seem to be ineffective; additionally, a contemporary expansion of tropical M. henlei into subtropical and temperate waters may have been observed. PMID:25937903

  4. Examining Teachers' Hurdles to `Science for All'

    NASA Astrophysics Data System (ADS)

    Southerland, Sherry; Gallard, Alejandro; Callihan, Laurie

    2011-11-01

    The goal of this research is to identify science teachers' beliefs and conceptions that play an important role in shaping their understandings of and attempts to enact inclusive science teaching practices. We examined the work products, both informal (online discussions, email exchanges) and formal (papers, unit plans, peer reviews), of 14 teachers enrolled in a master's degree course focused on diversity in science teaching and learning. These emerging understandings were member-checked via a series of interviews with a subset of these teachers. Our analysis was conducted in two stages: (1) describing the difficulties the teachers identified for themselves in their attempts to teach science to a wide range of students in their classes and (2) analyzing these self-identified barriers for underlying beliefs and conceptions that serve to prohibit or allow for the teachers' understanding and enactment of equitable science instruction. The teachers' self-identified barriers were grouped into three categories: students, broader social infrastructure, and self. The more fundamental barriers identified included teacher beliefs about the ethnocentrism of the mainstream, essentialism/individualism, and beliefs about the meritocracy of schooling. The implications of these hurdles for science teacher education are discussed.

  5. Conductivity equations of protons transporting through 2D crystals obtained with the rate process theory and free volume concept

    NASA Astrophysics Data System (ADS)

    Hao, Tian; Xu, Yuanze; Hao, Ting

    2018-04-01

    The Eyring's rate process theory and free volume concept are employed to treat protons (or other particles) transporting through a 2D (two dimensional) crystal like graphene and hexagonal boron nitride. The protons are assumed to be activated first in order to participate conduction and the conduction rate is dependent on how much free volume available in the system. The obtained proton conductivity equations show that only the number of conduction protons, proton size and packing structure, and the energy barrier associated with 2D crystals are critical; the quantization conductance is unexpectedly predicted with a simple Arrhenius type temperature dependence. The predictions agree well with experimental observations and clear out many puzzles like much smaller energy barrier determined from experiments than from the density function calculations and isotope separation rate independent of the energy barrier of 2D crystals, etc. Our work may deepen our understandings on how protons transport through a membrane and has direct implications on hydrogen related technology and proton involved bioprocesses.

  6. Optimum allocation of conservation funds and choice of conservation programs for a set of African cattle breeds

    PubMed Central

    Reist-Marti, Sabine B; Abdulai, Awudu; Simianer, Henner

    2006-01-01

    Although funds for livestock conservation are limited there is little known about the optimal allocation of conservation funds. A new algorithm was used to allocate Mio US$ 1, 2, 3, 5 or unlimited funds, discounted over 50 years, on 23 African cattle breeds conserved with four different possible conservation programs. Additionally, Mio US$ 1 was preferably allocated to breeds with special traits. The conceptional in situ conservation programs strongly involve breeders and give them part of the responsibility for the conservation of the breed. Therefore, the pure in situ conservation was more efficient than cryoconservation or combined in situ and cryoconservation. The average annual discounted conservation cost for a breed can be as low as US$ 1000 to US$ 4400 depending on the design of the conservation program and the economic situation of the country of conservation. The choice of the breeds and the optimal conservation program and the amount of money allocated to each breed depend on many factors such as the amount of funds available, the conservation potential of each breed, the effects of the conservation program as well as its cost. With Mio US$ 1, 64% of the present diversity could be maintained over 50 years, which is 13% more than would be maintained if no conservation measures were implemented. Special traits could be conserved with a rather small amount of the total funds. Diversity can not be conserved completely, not even with unlimited funds. A maximum of 92% of the present diversity could be conserved with Mio US$ 10, leaving 8% of the diversity to unpredictable happenings. The suggested algorithm proved to be useful for optimal allocation of conservation funds. It allocated the funds optimally among breeds by identifying the most suited conservation program for each breed, also accounting for differences in currency exchange rates between the different countries. PMID:16451794

  7. Barriers of lean construction implementation in the Moroccan construction industry

    NASA Astrophysics Data System (ADS)

    Bajjou, Mohamed Saad; Chafi, Anas

    2018-04-01

    Improving the production system performance has become a fundamental pillar that must be taken into consideration in the construction industry. Recent developments in the construction sector have led to renewed interest in new techniques of management. Lean Construction is a very effective approach that has gained a high popularity by its ability to eliminate waste and maximize the value for the customer. Although both developed and developing countries have gained large benefits by implementing Lean Construction approach, several experiences showed many barriers that are hindering its implementation especially in developing countries. This paper aims to assess the critical barriers to the successful implementation in the Moroccan construction industry. Based on a literature review, followed by an analysis of data collected from a questionnaire survey which targeted 330 practitioners in the Moroccan construction field, several barriers were identified as key barriers. The findings of this investigation revealed that there are significant barriers such as Lack of knowledge about Lean Construction concepts, Unskilled Human Resources, and insufficient financial resources.

  8. Skin Barrier Disruption - A Requirement for Allergen Sensitization?

    PubMed Central

    De Benedetto, Anna; Kubo, Akiharu; Beck, Lisa A.

    2011-01-01

    For at least half a century, noninvasive techniques have been available to quantify skin barrier function, and these have shown that a number of human skin conditions and disorders are associated with defects in skin permeability. In the last decade, several genes responsible for skin barrier defects observed in both monogenetic and complex, polygenic disorders have been elucidated and functionally characterized. This has led to an explosion of work in the last six years that has identified pathways connecting epidermal barrier disruption and antigen uptake as well as the quality and/or magnitude of the antigen-specific adaptive immune response. This review will introduce the notion that diseases arise from the dynamic crosstalk that occurs between the skin barrier and immune system using atopic dermatitis or eczema as the disease prototype. Nevertheless, the concepts put forth are highly relevant to a number of antigen-driven disorders for which skin barrier is at least transiently compromised such as psoriasis, allergic contact dermatitis and blistering disorders. PMID:22217737

  9. Quantitative analysis of nanoparticle transport through in vitro blood-brain barrier models

    PubMed Central

    Åberg, Christoffer

    2016-01-01

    ABSTRACT Nanoparticle transport through the blood-brain barrier has received much attention of late, both from the point of view of nano-enabled drug delivery, as well as due to concerns about unintended exposure of nanomaterials to humans and other organisms. In vitro models play a lead role in efforts to understand the extent of transport through the blood-brain barrier, but unique features of the nanoscale challenge their direct adaptation. Here we highlight some of the differences compared to molecular species when utilizing in vitro blood-brain barrier models for nanoparticle studies. Issues that may arise with transwell systems are discussed, together with some potential alternative methodologies. We also briefly review the biomolecular corona concept and its importance for how nanoparticles interact with the blood-brain barrier. We end with considering future directions, including indirect effects and application of shear and fluidics-technologies. PMID:27141425

  10. Strategic group stability: evidence from the health care industry.

    PubMed

    Churchman, Richard L; Woodard, Beth

    2004-01-01

    To better understand strategic group stability and the associated mobility barriers concept, we surveyed health care administrators on their reasons for remaining in their current strategic group. We offer administrators' responses to the strategic group stability (mobility barrier) question. Decision-makers may be unaware of these cognitive biases (e.g., group-level world-view and resource similarity) and may not recognize the extent to which they are reducing their strategic alternatives.

  11. Neuroimmune Axes of the Blood–Brain Barriers and Blood–Brain Interfaces: Bases for Physiological Regulation, Disease States, and Pharmacological Interventions

    PubMed Central

    Erickson, Michelle A.

    2018-01-01

    Central nervous system (CNS) barriers predominantly mediate the immune-privileged status of the brain, and are also important regulators of neuroimmune communication. It is increasingly appreciated that communication between the brain and immune system contributes to physiologic processes, adaptive responses, and disease states. In this review, we discuss the highly specialized features of brain barriers that regulate neuroimmune communication in health and disease. In section I, we discuss the concept of immune privilege, provide working definitions of brain barriers, and outline the historical work that contributed to the understanding of CNS barrier functions. In section II, we discuss the unique anatomic, cellular, and molecular characteristics of the vascular blood–brain barrier (BBB), blood–cerebrospinal fluid barrier, and tanycytic barriers that confer their functions as neuroimmune interfaces. In section III, we consider BBB-mediated neuroimmune functions and interactions categorized as five neuroimmune axes: disruption, responses to immune stimuli, uptake and transport of immunoactive substances, immune cell trafficking, and secretions of immunoactive substances. In section IV, we discuss neuroimmune functions of CNS barriers in physiologic and disease states, as well as pharmacological interventions for CNS diseases. Throughout this review, we highlight many recent advances that have contributed to the modern understanding of CNS barriers and their interface functions. PMID:29496890

  12. The Perception of Concurrent Sound Objects in Harmonic Complexes Impairs Gap Detection

    ERIC Educational Resources Information Center

    Leung, Ada W. S.; Jolicoeur, Pierre; Vachon, Francois; Alain, Claude

    2011-01-01

    Since the introduction of the concept of auditory scene analysis, there has been a paucity of work focusing on the theoretical explanation of how attention is allocated within a complex auditory scene. Here we examined signal detection in situations that promote either the fusion of tonal elements into a single sound object or the segregation of a…

  13. Materiales en Marcha Para El Esfuerzo Bilingue--Bicultural (Materials on the March for the Promotion of Bilingualism/Biculturalism), March 1973.

    ERIC Educational Resources Information Center

    San Diego City Schools, CA.

    This newsletter is designed to promote the concept of bilingual-bicultural education. Included in this issue are articles on "Bilingual Education: Acceptance and Allocation,""A World History Reference,""History Teachers, Take Heart,""Social Studies Materials in Spanish," and "Pride of Aztlan." Articles appear in Spanish and English. Included is a…

  14. Demystifying governance and its role for transitions in urban social–ecological systems

    Treesearch

    T.A. Muñoz-Erickson; L.K. Campbell; D.L. Childers; J.M. Grove; D.M. Iwaniec; S.T.A. Pickett; Michelle Romolini; Erika S. Svendsen

    2016-01-01

    Governance is key to sustainable urban transitions. Governance is a system of social, power, and decision-making processes that acts as a key driver of resource allocation and use, yet ecologists even urban ecologists–seldom consider governance concepts in their work. Transitions to more sustainable futures are becoming increasingly important to the management of many...

  15. The use of VIEWIT and perspective plot to assist in determining the landscape's visual absorption capability

    Treesearch

    Wayne Tlusty

    1979-01-01

    The concept of Visual Absorption Capability (VAC) is widely used by Forest Service Landscape Architects. The use of computer generated graphics can aid in combining times an area is seen, distance from observer and land aspect relative viewer; to determine visual magnitude. Perspective Plot allows both fast and inexpensive graphic analysis of VAC allocations, for...

  16. Special Education in the City: How Has the Money Been Spent and What Do We Have To Show for It?

    ERIC Educational Resources Information Center

    Parrish, Thomas B.; Bitter, Catherine Sousa

    2003-01-01

    This article discusses how the concept of efficiency in special education services is translated into specific practices. A paradigm is presented that quantifies a measure of student need, ties school allocations to student needs, tracks actual expenditures on special education, and links those expenditures to quantifiable measures of student…

  17. The NATO Unmanned Aircraft System Human Systems Integration Guidebook

    DTIC Science & Technology

    2012-11-01

    Stakeholders HSI Management Activity Goals Project SMEs HCR Acceptance Methods & Criteria Figure 2. Overarching HSI Goal Structure ...88ABW Clear 10/21/2013; 88ABW-2013-4442 55 N NATO North Atlantic Treaty Organisation NTSB National Transportation Safety Board S SME Subject...support the organisation Personnel trained to support safety Operational Concepts HSI Technical Activity Goals Allocation of Functions

  18. ERO Caught in the Act (Again): Limiting Inclusion to Suit Policy

    ERIC Educational Resources Information Center

    McMaster, Christopher

    2013-01-01

    In 2010 the Education Review Office (ERO) was tasked with reporting on the progress of New Zealand schools in the inclusion of students with high needs. This paper will explore how ERO limited the concept of inclusion to suit Government policy and limit discussion of inclusion to the parameters set by the resource allocation scheme known as…

  19. Exploring the Politics of Differential Resource Allocation: Implications for Policy Design and Leadership Practice

    ERIC Educational Resources Information Center

    Halverson, Thomas J.; Plecki, Margaret L.

    2015-01-01

    This qualitative case study explores the political and leadership challenges imbedded within the implementation of a district-wide resource reallocation policy. Based on a two-year study of a medium-sized district's efforts to address changing demographics of families in the district and a widening achievement gap, we draw upon concepts from…

  20. Activating Learning in Engineering Education Using ICT and the Concept of "Flipping the Classroom"

    ERIC Educational Resources Information Center

    Lucke, Terry; Dunn, Peter K.; Christie, Michael

    2017-01-01

    This case study trialled the introduction of a student-response system (Top Hat) in a third-year engineering Fluid Mechanics course (n = 44) to improve student engagement, motivation and cognition. It was recognised that for the potential benefits of student-response systems (SRSs) to be fully realised, more time must be allocated for student…

  1. Technology Challenges and Opportunities for Very Large In-Space Structural Systems

    NASA Technical Reports Server (NTRS)

    Belvin, W. Keith; Dorsey, John T.; Watson, Judith J.

    2009-01-01

    Space solar power satellites and other large space systems will require creative and innovative concepts in order to achieve economically viable designs. The mass and volume constraints of current and planned launch vehicles necessitate highly efficient structural systems be developed. In addition, modularity and in-space deployment/construction will be enabling design attributes. While current space systems allocate nearly 20 percent of the mass to the primary structure, the very large space systems of the future must overcome subsystem mass allocations by achieving a level of functional integration not yet realized. A proposed building block approach with two phases is presented to achieve near-term solar power satellite risk reduction with accompanying long-term technology advances. This paper reviews the current challenges of launching and building very large space systems from a structures and materials perspective utilizing recent experience. Promising technology advances anticipated in the coming decades in modularity, material systems, structural concepts, and in-space operations are presented. It is shown that, together, the current challenges and future advances in very large in-space structural systems may provide the technology pull/push necessary to make solar power satellite systems more technically and economically feasible.

  2. Microwave-Driven Multifunctional Capability of Membrane Structures

    NASA Technical Reports Server (NTRS)

    Choi, Sang H.; Chu, Sang-Hyong; Song, Kyo D.; King, Glen C.

    2002-01-01

    A large, ultra lightweight space structure, such as solar sails and Gossamer spacecrafts, requires a distributed power source to alleviate wire networks, unlike the localized on-board power infrastructures typically found in most small spacecrafts. The concept of microwave-driven multifunctional capability for membrane structures is envisioned as the best option to alleviate the complexity associated with hard-wired control circuitry and on-board power infrastructures. A rectenna array based on a patch configuration for high voltage output was developed to drive membrane actuators, sensors, probes, or other devices. Networked patch rectenna array receives and converts microwave power into a DC power for an array of smart actuators. To use microwave power effectively, the concept of a power allocation and distribution (PAD) circuit is adopted for networking a rectenna/actuator patch array. The use of patch rectennas adds a significant amount of rigidity to membrane flexibility and they are relatively heavy. A dipole rectenna array (DRA) appears to be ideal for thin-film membrane structures, since DRA is flexible and light. Preliminary design and fabrication of PAD circuitry that consists of a few nodal elements were made for laboratory testing. The networked actuators were tested to correlate the network coupling effect, power allocation and distribution, and response time.

  3. Low-resolution gamma-ray spectrometry for an information barrier based on a multi-criteria template-matching approach

    NASA Astrophysics Data System (ADS)

    Göttsche, Malte; Schirm, Janet; Glaser, Alexander

    2016-12-01

    Gamma-ray spectrometry has been successfully employed to identify unique items containing special nuclear materials. Template information barriers have been developed in the past to confirm items as warheads by comparing their gamma signature to the signature of true warheads. Their development has, however, not been fully transparent, and they may not be sensitive to some relevant evasion scenarios. We develop a fully open template information barrier concept, based on low-resolution measurements, which, by design, reduces the extent of revealed sensitive information. The concept is based on three signatures of an item to be compared to a recorded template. The similarity of the spectrum is assessed by a modification of the Kolmogorov-Smirnov test to confirm the isotopic composition. The total gamma count rate must agree with the template as a measure of the projected surface of the object. In order to detect the diversion of fissile material from the interior of an item, a polyethylene mask is placed in front of the detector. Neutrons from spontaneous and induced fission events in the item produce 2.223 MeV gamma rays from neutron capture by hydrogen-1 in the mask. This peak is detected and its intensity scales with the item's fissile mass. The analysis based on MCNP Monte Carlo simulations of various plutonium configurations suggests that this concept can distinguish a valid item from a variety of invalid ones. The concept intentionally avoids any assumptions about specific spectral features, such as looking for specific gamma peaks of specific isotopes, thereby facilitating a fully unclassified discussion. By making all aspects public and allowing interested participants to contribute to the development and benchmarking, we enable a more open and inclusive discourse on this matter.

  4. Vertical ridge augmentation with autogenous bone grafts 3 years after loading: resorbable barriers versus titanium-reinforced barriers. A randomized controlled clinical trial.

    PubMed

    Merli, Mauro; Lombardini, Francesco; Esposito, Marco

    2010-01-01

    To compare the efficacy of two different techniques for vertical bone regeneration at implant placement with particulated autogenous bone at 3 years after loading: resorbable collagen barriers supported by osteosynthesis plates and nonresorbable titanium-reinforced expanded polytetrafluoroethylene barriers. Twenty-two partially edentulous patients requiring vertical bone augmentation were randomly allocated to two treatment groups, each composed of 11 patients. Prosthetic and implant failures, complications, the amount of vertically regenerated bone, and peri-implant marginal bone levels were recorded by independent and blinded assessors. The implant site requiring the most vertical bone regeneration was selected in each patient for bone level assessment. The follow-up time ranged from provisional loading to 3 years after loading. Analysis of covariance and paired t tests were conducted to compare means at the .05 level of significance. No patient dropped out or was excluded at the 3-year follow-up. No prosthetic failures and no implant failures or complications occurred after loading. There was no statistically significant difference in bone loss between the two groups at either 1 year or 3 years. Both groups had gradually lost a statistically significant amount of peri-implant bone at 1 and 3 years (P < .05). After 3 years, patients treated with resorbable barriers had lost a mean of 0.55 mm of bone; patients who had received nonresorbable barriers showed a mean of 0.53 mm of bone loss. Up to 3 years after implant loading, no failures or complications occurred and peri-implant marginal bone loss was minimal. Vertically regenerated bone can be successfully maintained after functional loading.

  5. Barriers to gene exchange in hybridizing field crickets: the role of male courtship effort and cuticular hydrocarbons.

    PubMed

    Maroja, Luana S; McKenzie, Zachary M; Hart, Elizabeth; Jing, Joy; Larson, Erica L; Richardson, David P

    2014-03-28

    Pre-zygotic barriers often involve some form of sexual selection, usually interpreted as female choice, as females are typically the choosier sex. However, males typically show some mate preferences, which are increasingly reported. Here we document previously uncharacterized male courtship behavior (effort and song) and cuticular hydrocarbon (CHC) profiles in the hybridizing crickets Gryllus firmus and G. pennsylvanicus. These two species exhibit multiple barriers to gene exchange that act throughout their life history, including a behavioral barrier that results in increased time to mate in heterospecific pairs. We demonstrated that male mate choice (as courtship effort allocation) plays a more important role in the prezygotic behavioral barrier than previously recognized. In gryllids females ultimately decide whether or not to mate, yet we found males were selective by regulating courtship effort intensity toward the preferred (conspecific) females. Females were also selective by mating with more intensely courting males, which happened to be conspecifics. We report no differences in courtship song between the two species and suggest that the mechanism that allows males to act differentially towards conspecific and heterospecific females is the cuticular hydrocarbon (CHC) composition. CHC profiles differed between males and females of both species, and there were clear differences in CHC composition between female G. firmus and G. pennsylvanicus but not between the males of each species. Although many barriers to gene exchange are known in this system, the mechanism behind the mate recognition leading to reduced heterospecific mating remains unknown. The CHC profiles might be the phenotypic cue that allow males to identify conspecifics and thus to adjust their courtship intensity accordingly, leading to differential mating between species.

  6. A Systematic Content Analysis of Policy Barriers Impeding Access to Opioid Medication in Central and Eastern Europe: Results of ATOME.

    PubMed

    Larjow, Eugenia; Papavasiliou, Evangelia; Payne, Sheila; Scholten, Willem; Radbruch, Lukas

    2016-01-01

    Reliable access to opioid medication is critical to delivering effective pain management, adequate treatment of opioid dependence, and quality palliative care. However, more than 80% of the world population is estimated to be inadequately treated for pain because of difficulties in accessing opioids. Although barriers to opioid access are primarily associated with restrictive laws, regulations, and licensing requirements, a key problem that significantly limits opioid access relates to policy constraints. To identify and explore policy barriers to opioid access in 12 Eastern and Central European countries involved in the Access to Opioid Medication in Europe project, funded by the European Community's Seventh Framework (FP7/2007-2013, no. 222994) Programme. A systematic content analysis of texts retrieved from documents (e.g., protocols of national problem analyses, strategic planning worksheets, and executive summaries) compiled, reviewed, approved, and submitted by either the Access to Opioid Medication in Europe consortium or the national country teams (comprising experts in pain management, harm reduction, and palliative care) between September 2011 and April 2014 was performed. Twenty-five policy barriers were identified (e.g., economic crisis, bureaucratic issues, lack of training initiatives, stigma, and discrimination), classified under four predetermined categories (financial/economic aspects and governmental support, formularies, education and training, and societal attitudes). Key barriers related to issues of funding allocation, affordability, knowledge, and fears associated with opioids. Reducing barriers and improving access to opioids require policy reform at the governmental level with a set of action plans being formulated and concurrently implemented and aimed at different levels of social, education, and economic policy change. Copyright © 2016 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  7. Barrier island facies models and recognition criteria

    NASA Astrophysics Data System (ADS)

    Mulhern, J.; Johnson, C. L.

    2017-12-01

    Barrier island outcrops record transgressive shoreline motion at geologic timescales, providing integral clues to understanding how coastlines respond to rising sea levels. However, barrier island deposits are difficult to recognize. While significant progress has been made in understanding the modern coastal morphodynamics, this insight is not fully leveraged in existing barrier island facies models. Excellent outcrop exposures of the paralic Upper Cretaceous Straight Cliffs Formation of southern Utah provide an opportunity to revise facies models and recognition criteria for barrier island deposits. Preserved barrier islands are composed of three main architectural elements (shorefaces, tidal inlets, and tidal channels) which occur independently or in combination to create larger-scale barrier island deposits. Barrier island shorefaces record progradation, while barrier island tidal inlets record lateral migration, and barrier island tidal channels record aggradation within the tidal inlet. Four facies associations are used to describe and characterize these barrier island architectural elements. Barrier islands occur in association with backarrier fill and internally contain lower and upper shoreface, high-energy upper shoreface, and tidal channel facies. Barrier islands bound lagoons or estuaries, and are distinguished from other shoreface deposits by their internal facies and geometry, association with backbarrier facies, and position within transgressive successions. Tidal processes, in particular tidal inlet migration and reworking of the upper shoreface, also distinguish barrier island deposits. Existing barrier island models highlight the short term heterogeneous and dynamic nature of barrier island systems, yet overlook processes tied to geologic time scales, such as multi-directional motion, erosion, and reworking, and their expressions in preserved barrier island strata. This study uses characteristic outcrop expressions of barrier island successions to exemplify how modern morphodynamic concepts can be combined with geologic time-scale processes to update understanding of ancient barrier island motion and preservation.

  8. [Barriers and opportunities for the regulation of food and beverage advertising to children in Mexico].

    PubMed

    Théodore, Florence; Juárez-Ramírez, Clara; Cahuana-Hurtado, Lucero; Blanco, Ilian; Tolentino-Mayo, Lizbeth; Bonvecchio, Anabelle

    2014-01-01

    To identify barriers and opportunities for the regulation of food and beverage advertising to children. A qualitative study. Fourteen key informants from the congress, private sector, officials from the ministry of health and academics involved in the issue of regulation of advertising were interviewed. Barriers identified: conception of obesity as an individual problem, minimization of the negative effects on health, definition of the vulnerability of children bounded to their cognitive development. Facilitators support from various sectors of society regulation, extensive scientific discussion on the subject, successful experience and its lessons on tabacco industry. Mexico has key elements for achieving effective regulation on advertising.

  9. Advanced Environmental Barrier Coatings Development for Si-Based Ceramics

    NASA Technical Reports Server (NTRS)

    Zhu, Dong-Ming; Choi, R. Sung; Robinson, Raymond C.; Lee, Kang N.; Bhatt, Ramakrishna T.; Miller, Robert A.

    2005-01-01

    Advanced environmental barrier coating concepts based on multi-component HfO2 (ZrO2) and modified mullite systems are developed for monolithic Si3N4 and SiC/SiC ceramic matrix composite (CMC) applications. Comprehensive testing approaches were established using the water vapor cyclic furnace, high pressure burner rig and laser heat flux steam rig to evaluate the coating water vapor stability, cyclic durability, radiation and erosion resistance under simulated engine environments. Test results demonstrated the feasibility and durability of the environmental barrier coating systems for 2700 to 3000 F monolithic Si3N4 and SiC/SiC CMC component applications. The high-temperature-capable environmental barrier coating systems are being further developed and optimized in collaboration with engine companies for advanced turbine engine applications.

  10. Barriers and enablers to academic health leadership.

    PubMed

    Bharwani, Aleem; Kline, Theresa; Patterson, Margaret; Craighead, Peter

    2017-02-06

    Purpose This study sought to identify the barriers and enablers to leadership enactment in academic health-care settings. Design/methodology/approach Semi-structured interviews ( n = 77) with programme stakeholders (medical school trainees, university leaders, clinical leaders, medical scientists and directors external to the medical school) were conducted, and the responses content-analysed. Findings Both contextual and individual factors were identified as playing a role in affecting academic health leadership enactment that has an impact on programme development, success and maintenance. Contextual factors included sufficient resources allocated to the programme, opportunities for learners to practise leadership skills, a competent team around the leader once that person is in place, clear expectations for the leader and a culture that fosters open communication. Contextual barriers included highly bureaucratic structures, fear-of-failure and non-trusting cultures and inappropriate performance systems. Programmes were advised to select participants based on self-awareness, strong communication skills and an innovative thinking style. Filling specific knowledge and skill gaps, particularly for those not trained in medical school, was viewed as essential. Ineffective decision-making styles and tendencies to get involved in day-to-day activities were barriers to the development of academic health leaders. Originality/value Programmes designed to develop academic health-care leaders will be most effective if they develop leadership at all levels; ensure that the organisation's culture, structure and processes reinforce positive leadership practices; and recognise the critical role of teams in supporting its leaders.

  11. Why are IPTp coverage targets so elusive in sub-Saharan Africa? A systematic review of health system barriers.

    PubMed

    Thiam, Sylla; Kimotho, Victoria; Gatonga, Patrick

    2013-10-03

    Use of intermittent preventive treatment (IPTp) is a proven cost-effective intervention for preventing malaria in pregnancy. However, despite the roll-out of IPTp policies across Africa more than ten years ago, utilization levels remain low. This review sought to consolidate scattered evidence as to the health system barriers for IPTp coverage in the continent. Relevant literature from Africa was systematically searched, reviewed and synthesized. Only studies containing primary data were considered. Studies reveal that: (i) poor leadership and governance contribute to slow decentralization of programme management, lack of harmonized guidelines, poor accountability mechanisms, such as robust monitoring and evaluation systems; (ii) low budgetary allocation towards policy implementation slows scale-up, while out-of-pocket expenditure deters women from seeking antenatal services that include IPTp; (iii) there are rampant human resource challenges including low staff motivation levels attributed to such factors as incorrect knowledge of IPTp recommendations and inadequate staffing; (iv) implementation of IPTp policies is hampered by prevailing service delivery barriers, such as long waiting time, long distances to health facilities and poor service provider/client relations; and (v) drug stock-outs and poor management of information and supply chains impair sustained availability of drugs for IPTp. For successful IPTp policy implementation, it is imperative that malaria control programmes target health system barriers that result in low coverage and hence programme ineffectiveness.

  12. Microvillar Ca++ signaling: a new view of an old problem.

    PubMed

    Lange, K

    1999-07-01

    Proceeding from the recent finding that the main components of the Ca++ signal pathway are located in small membrane protrusions on the surface of differentiated cells, called microvilli, a novel concept of cellular Ca++ signaling was developed. The main features of this concept can be summarized as follows: Microvilli are formed on the cell surface of differentiating or resting cells from exocytic membrane domains, growing out from the cell surface by elongation of an internal bundle of actin filaments. The microvillar tip membranes contain all functional important proteins synthesized such as ion channels and transporters for energy-providing substrates and structural components, which are, in rapidly growing undifferentiated cells, distributed over the whole cell surface by lateral diffusion. The microvillar shaft structure, a bundle of actin filaments, forms a dense cytoskeletal matrix tightly covered by the microvillar lipid membrane and represents an effective diffusion barrier separating the microvillar tip compartment (entrance compartment) from the cytoplasm. This diffusion barrier prevents the passage of low molecular components such as Ca++ glucose and other relevant substrates from the entrance compartment into the cytoplasm. The effectiveness of the actin-based diffusion barrier is modulated by various signal pathways and effectors, most importantly, by the actin-depolymerizing/reorganizing activity of the phospholipase C (PLC)-coupled Ca++ signaling. Moreover, the microvillar bundle of actin filaments plays a dual role in Ca++ signaling. It combines the function of a diffusion barrier, preventing Ca++ influx into the resting cell, with that of a high-affinity, ATP-dependent, and IP3-sensitive Ca++ store. Activation of Ca++ signaling via PLC-coupled receptors simultaneously empties Ca++ stores and activates the influx of external Ca++. The presented concept of Ca++ signaling is compatible with all established data on Ca++ signaling. Properties of Ca++ signaling, that could not be reconciled with the basic principles of the current hypothesis, are intrinsic properties of the new concept. Quantal Ca++ release, Ca(++)-induced Ca++ release (CICR), the coupling phenomen between the filling state of the Ca++ store and the activity of the Ca++ influx pathway, as well as the various yet unexplained complex kinetics of Ca++ uptake and release can be explained on a common mechanistic basis.

  13. Achieving Crossed Strong Barrier Coverage in Wireless Sensor Network.

    PubMed

    Han, Ruisong; Yang, Wei; Zhang, Li

    2018-02-10

    Barrier coverage has been widely used to detect intrusions in wireless sensor networks (WSNs). It can fulfill the monitoring task while extending the lifetime of the network. Though barrier coverage in WSNs has been intensively studied in recent years, previous research failed to consider the problem of intrusion in transversal directions. If an intruder knows the deployment configuration of sensor nodes, then there is a high probability that it may traverse the whole target region from particular directions, without being detected. In this paper, we introduce the concept of crossed barrier coverage that can overcome this defect. We prove that the problem of finding the maximum number of crossed barriers is NP-hard and integer linear programming (ILP) is used to formulate the optimization problem. The branch-and-bound algorithm is adopted to determine the maximum number of crossed barriers. In addition, we also propose a multi-round shortest path algorithm (MSPA) to solve the optimization problem, which works heuristically to guarantee efficiency while maintaining near-optimal solutions. Several conventional algorithms for finding the maximum number of disjoint strong barriers are also modified to solve the crossed barrier problem and for the purpose of comparison. Extensive simulation studies demonstrate the effectiveness of MSPA.

  14. Pilot Study to Evaluate the Effect of Topical Dimethicone on Clinical Signs and Skin Barrier Function in Dogs with Naturally Occurring Atopic Dermatitis

    PubMed Central

    Pellicoro, C.; Marsella, R.; Ahrens, K.

    2013-01-01

    This study investigated the effects of a skin protectant solution (dimethicone 2%) on clinical signs and skin barrier function in canine atopic dermatitis (AD). Eighteen dogs with AD were randomly divided into two groups, one received dimethicone and the other received the vehicle (cyclomethicone) on selected areas (pinnae, groin, and axillae) daily for 4 weeks. Owners and investigators were blinded regarding group allocation. Clinical efficacy was evaluated using a scoring system and skin barrier by measuring the transepidermal water loss. Twelve dogs completed the study (50% drop rate in the vehicle and 20% in the dimethicone). For clinical signs, analysis of variance showed an effect of time (P < 0.005; day 0 > day 28) and region (axillae < groin < pinnae) but no effect of group or group × time interaction. For transepidermal water loss, analysis of variance showed only a main effect of region (axillae > pinnae > groin). Pearson found no correlation between transepidermal water loss and clinical scores. In this pilot study dimethicone had no significant effect on clinical signs and transepidermal water loss in canine atopic dermatitis. PMID:23710417

  15. Optimal Decisions for Organ Exchanges in a Kidney Paired Donation Program.

    PubMed

    Li, Yijiang; Song, Peter X-K; Zhou, Yan; Leichtman, Alan B; Rees, Michael A; Kalbfleisch, John D

    2014-05-01

    The traditional concept of barter exchange in economics has been extended in the modern era to the area of living-donor kidney transplantation, where one incompatible donor-candidate pair is matched to another pair with a complementary incompatibility, such that the donor from one pair gives an organ to a compatible candidate in the other pair and vice versa. Kidney paired donation (KPD) programs provide a unique and important platform for living incompatible donor-candidate pairs to exchange organs in order to achieve mutual benefit. In this paper, we propose novel organ allocation strategies to arrange kidney exchanges under uncertainties with advantages, including (i) allowance for a general utility-based evaluation of potential kidney transplants and an explicit consideration of stochastic features inherent in a KPD program; and (ii) exploitation of possible alternative exchanges when the originally planned allocation cannot be fully executed. This allocation strategy is implemented using an integer programming (IP) formulation, and its implication is assessed via a data-based simulation system by tracking an evolving KPD program over a series of match runs. Extensive simulation studies are provided to illustrate our proposed approach.

  16. Marginal Contribution-Based Distributed Subchannel Allocation in Small Cell Networks.

    PubMed

    Shah, Shashi; Kittipiyakul, Somsak; Lim, Yuto; Tan, Yasuo

    2018-05-10

    The paper presents a game theoretic solution for distributed subchannel allocation problem in small cell networks (SCNs) analyzed under the physical interference model. The objective is to find a distributed solution that maximizes the welfare of the SCNs, defined as the total system capacity. Although the problem can be addressed through best-response (BR) dynamics, the existence of a steady-state solution, i.e., a pure strategy Nash equilibrium (NE), cannot be guaranteed. Potential games (PGs) ensure convergence to a pure strategy NE when players rationally play according to some specified learning rules. However, such a performance guarantee comes at the expense of complete knowledge of the SCNs. To overcome such requirements, properties of PGs are exploited for scalable implementations, where we utilize the concept of marginal contribution (MC) as a tool to design learning rules of players’ utility and propose the marginal contribution-based best-response (MCBR) algorithm of low computational complexity for the distributed subchannel allocation problem. Finally, we validate and evaluate the proposed scheme through simulations for various performance metrics.

  17. On the dynamics of implicit emotion regulation: counter-regulation after remembering events of high but not of low emotional intensity.

    PubMed

    Schwager, Susanne; Rothermund, Klaus

    2014-01-01

    Valence biases in attention allocation were assessed after remembering positive or negative personal events that were either still emotionally hot or to which the person had already adapted psychologically. Differences regarding the current state of psychological adjustment were manipulated experimentally by instructing participants to recall distant vs. recent events (Experiment 1) or affectively hot events vs. events to which the person had accommodated already (Experiment 2). Valence biases in affective processing were measured with a valence search task. Processes of emotional counter-regulation (i.e., attention allocation to stimuli of opposite valence to the emotional event) were elicited by remembering affectively hot events, whereas congruency effects (i.e., attention allocation to stimuli of the same valence as the emotional event) were obtained for events for which a final appraisal had already been established. The results of our study help to resolve conflicting findings from the literature regarding congruent vs. incongruent effects of remembering emotional events on affective processing. We discuss implications of our findings for the conception of emotions and for the dynamics of emotion regulation processes.

  18. Nurse manager succession planning: a concept analysis.

    PubMed

    Titzer, Jennifer L; Shirey, Maria R

    2013-01-01

    The current nursing leadership pipeline is inadequate and demands strategic succession planning methods. This article provides concept clarification regarding nurse manager succession planning. Attributes common to succession planning include organizational commitment and resource allocation, proactive and visionary leadership approach, and a mentoring and coaching environment. Strategic planning, current and future leadership analysis, high-potential identification, and leadership development are succession planning antecedents. Consequences of succession planning are improved leadership and organizational culture continuity, and increased leadership bench strength. Health care has failed to strategically plan for future leadership. Developing a strong nursing leadership pipeline requires deliberate and strategic succession planning. © 2013 Wiley Periodicals, Inc.

  19. IS THE LINK BETWEEN HEALTH AND WEALTH CONSIDERED IN DECISION MAKING? RESULTS FROM A QUALITATIVE STUDY.

    PubMed

    Garau, Martina; Shah, Koonal Kirit; Sharma, Priya; Towse, Adrian

    2015-01-01

    The aim of this study was to explore whether wealth effects of health interventions, including productivity gains and savings in other sectors, are considered in resource allocations by health technology assessment (HTA) agencies and government departments. To analyze reasons for including, or not including, wealth effects. Semi-structured interviews with decision makers and academic experts in eight countries (Australia, France, Germany, Italy, Poland, South Korea, Sweden, and the United Kingdom). There is evidence suggesting that health interventions can produce economic gains for patients and national economies. However, we found that the link between health and wealth does not influence decision making in any country with the exception of Sweden. This is due to a combination of factors, including system fragmentation, methodological issues, and the economic recession forcing national governments to focus on short-term measures. In countries with established HTA processes and methods allowing, in principle, the inclusion of wider effects in exceptional cases or secondary analyses, it might be possible to overcome the methodological and practical barriers and see a more systematic consideration of wealth effect in decision making. This would be consistent with principles of efficient priority setting. Barriers for the consideration of wealth effects in government decision making are more fundamental, due to an enduring separation of budgets within the public sector and current financial pressures. However, governments should consider all relevant effects from public investments, including healthcare, even when benefits can only be captured in the medium- and long-term. This will ensure that resources are allocated where they bring the best returns.

  20. Surge capacity for response to bioterrorism in hospital clinical microbiology laboratories.

    PubMed

    Shapiro, Daniel S

    2003-12-01

    Surge capacity is the ability to rapidly mobilize to meet an increased demand. While large amounts of federal funding have been allocated to public health laboratories, little federal funding has been allocated to hospital microbiology laboratories. There are concerns that hospital laboratories may have inadequate surge capacities to deal with a significant bioterrorism incident. A workflow analysis of a clinical microbiology laboratory that serves an urban medical center was performed to identify barriers to surge capacity in the setting of a bioterrorism event and to identify solutions to these problems. Barriers include a national shortage of trained medical technologists, the inability of clinical laboratories to deal with a dramatic increase in the number of blood cultures, a delay while manufacturers increase production of critical products and then transport and deliver these products to clinical laboratories, and a shortage of class II biological safety cabinets. Federal funding could remedy staffing shortages by making the salaries of medical technologists comparable to those of similarly educated health care professionals and by providing financial incentives for students to enroll in clinical laboratory science programs. Blood culture bottles, and possibly continuous-monitoring blood culture instruments, should be added to the national antibiotic stockpile. Federal support must ensure that companies that manufacture essential laboratory supplies are capable of rapidly scaling up production. Hospitals must provide increased numbers of biological safety cabinets and amounts of space dedicated to clinical microbiology laboratories. Laboratories should undertake limited cross-training of technologists, ensure that adequate packaging supplies are available, and be able to move to a 4-day blood culture protocol.

  1. Estimation of within-stratum variance for sample allocation: Foreign commodity production forecasting

    NASA Technical Reports Server (NTRS)

    Chhikara, R. S.; Perry, C. R., Jr. (Principal Investigator)

    1980-01-01

    The problem of determining the stratum variances required for an optimum sample allocation for remotely sensed crop surveys is investigated with emphasis on an approach based on the concept of stratum variance as a function of the sampling unit size. A methodology using the existing and easily available information of historical statistics is developed for obtaining initial estimates of stratum variances. The procedure is applied to variance for wheat in the U.S. Great Plains and is evaluated based on the numerical results obtained. It is shown that the proposed technique is viable and performs satisfactorily with the use of a conservative value (smaller than the expected value) for the field size and with the use of crop statistics from the small political division level.

  2. Automated Pollution Control

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Patterned after the Cassini Resource Exchange (CRE), Sholtz and Associates established the Automated Credit Exchange (ACE), an Internet-based concept that automates the auctioning of "pollution credits" in Southern California. An early challenge of the Jet Propulsion Laboratory's Cassini mission was allocating the spacecraft's resources. To support the decision-making process, the CRE was developed. The system removes the need for the science instrument manager to know the individual instruments' requirements for the spacecraft resources. Instead, by utilizing principles of exchange, the CRE induces the instrument teams to reveal their requirements. In doing so, they arrive at an efficient allocation of spacecraft resources by trading among themselves. A Southern California RECLAIM air pollution credit trading market has been set up using same bartering methods utilized in the Cassini mission in order to help companies keep pollution and costs down.

  3. Efficacy of carprofen on conception rates in lactating dairy cows after subcutaneous or intrauterine administration at the time of breeding.

    PubMed

    Heuwieser, W; Iwersen, M; Goetze, L

    2011-01-01

    Manipulation of the reproductive tract can cause inflammatory processes in the endometrium and release of cytokines and prostaglandins. It has been shown that PGF2α has direct negative effects on embryonic survival and development. Treatment with nonsteroidal antiinflammatory drugs (e.g., ibuprofen lysinate, flunixin meglumine) might improve pregnancy rates after embryo transfer in recipient heifers. The primary objective of this study was to evaluate the effect of a nonsteroidal antiinflammatory drug on reproductive performance in lactating dairy cows when administered at the time of first-service artificial insemination (AI) based on the hypothesis that uterine manipulation during AI might be similarly intense compared with embryo transfer in its effect on prostaglandin release. A total of 970 cows (333 primiparous and 637 multiparous) from 17 Holstein dairy farms were enrolled. On the day of first AI, cows were randomly allocated to 1 of 3 treatment groups. Cows of group 1 received 1.4 mg/kg of body weight (BW) of carprofen subcutaneously immediately after AI (SC group). In group 2, 1.4 mg/kg of BW of carprofen was administered into the uterus using a sterile disposable catheter 12 to 24 h after AI (IU group). Animals of group 3 remained as untreated controls. First AI conception rate was similar for the SC group (42.2%) compared with the untreated control group (45.1%). A binary logistic regression model for the odds of conception at first AI revealed a negative effect of an intrauterine administration of carprofen on conception rate (38.3%). Cows allocated to the IU group had a lower likelihood of being pregnant within 200 d in milk than cows in the control group. In summary, subcutaneous treatment with the nonsteroidal antiinflammatory drug carprofen at the time of AI did not influence conception rate, whereas an intrauterine administration of carprofen 12 to 24 h after first AI had a negative effect on first-service conception rate in lactating dairy cows. Copyright © 2011 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  4. [Video-based self-control in surgical teaching. A new tool in a new concept].

    PubMed

    Dahmen, U; Sänger, C; Wurst, C; Arlt, J; Wei, W; Dondorf, F; Richter, B; Settmacher, U; Dirsch, O

    2013-10-01

    Image and video-based results and process control are essential tools of a new teaching concept for conveying surgical skills. The new teaching concept integrates approved teaching principles and new media. Every performance of exercises is videotaped and the result photographically recorded. The quality of the process and result becomes accessible for an analysis by the teacher and the student/learner. The learner is instructed to perform a criteria-based self-analysis of the video and image material by themselves. The new learning concept has so far been successfully applied in seven rounds within the newly designed modular class "Intensivkurs Chirurgische Techniken" (Intensive training of surgical techniques). Result documentation and analysis via digital picture was completed by almost every student. The quality of the results was high. Interestingly the result quality did not correlate with the time needed for the exercise. The training success had a lasting effect. The new and elaborate concept improves the quality of teaching. In the long run resources for patient care should be saved when training students according to this concept prior to performing tasks in the operating theater. These resources should be allocated for further refining innovative teaching concepts.

  5. Deployment of Total Quality Management in Navy Public Works Centers

    DTIC Science & Technology

    1994-08-01

    businesses cnAsider quality, rather that just price, as a primary determiner for purchasing materials and sub-units (Point 4); a reminder to never accept any...gem ts job to reduce barriers to quality (Point 12); the fact that managers and workers need traning and education in the concepts of quality to...TQM organization, managemet is responsible for removing the barriers or dissatisfiers and using the satisfiers to create both worker satisfaction and a

  6. Reorientation of health services: enablers and barriers faced by organisations when increasing health promotion capacity.

    PubMed

    McFarlane, K; Judd, J; Devine, S; Watt, K

    2016-08-01

    Issue addressed Primary healthcare settings are important providers of health promotion approaches. However, organisational challenges can affect their capacity to deliver these approaches. This review identified the common enablers and barriers health organisations faced and it aimed to explore the experiences health organisations, in particular Aboriginal organisations, had when increasing their health promotion capacity. Methods A systematic search of peer-reviewed literature was conducted. Articles published between 1990-2014 that focused on a health care-settings approach and discussed factors that facilitated or hindered an organisation's ability to increase health promotion capacity were included. Results Twenty-five articles met the inclusion criteria. Qualitative (n=18) and quantitative (n=7) study designs were included. Only one article described the experiences of an Aboriginal health organisation. Enablers included: management support, skilled staff, provision of external support to the organisation, committed staffing and financial resources, leadership and the availability of external partners to work with. Barriers included: lack of management support, lack of dedicated health promotion staff, staff lacking skills or confidence, competing priorities and a lack of time and resources allocated to health promotion activities. Conclusions While the literature highlighted the importance of health promotion work, barriers can limit the delivery of health promotion approaches within primary healthcare organisations. A gap in the literature exists about how Aboriginal health organisations face these challenges. So what? Primary healthcare organisations wanting to increase their health promotion capacity can pre-empt the common barriers and strengthen identified enablers through the shared learnings outlined in this review.

  7. Dynamic subframe allocation for mobile broadband m-health using IEEE 802.16j mobile multihop relay networks.

    PubMed

    Alinejad, Ali; Istepanian, R S H; Philip, N

    2012-01-01

    The concept of 4G health will be one of the key focus areas of future m-health research and enterprise activities in the coming years. WiMAX technology is one of the constituent 4G wireless technologies that provides broadband wireless access (BWA). Despite the fact that WiMAX is able to provide a high data rate in a relatively large coverage; this technology has specific limitations such as: coverage, signal attenuation problems due to shadowing or path loss, and limited available spectrum. The IEEE 802.16j mobile multihop relay (MMR) technology is a pragmatic solution designed to overcome these limitations. The aim of IEEE 802.16j MMR is to expand the IEEE 802.16e's capabilities with multihop features. In particular, the uplink (UL) and downlink (DL) subframe allocation in WiMAX network is usually fixed. However, dynamic frame allocation is a useful mechanism to optimize uplink and downlink subframe size dynamically based on the traffic conditions through real-time traffic monitoring. This particular mechanism is important for future WiMAX based m-health applications as it allows the tradeoff in both UL and DL channels. In this paper, we address the dynamic frame allocation issue in IEEE 802.16j MMR network for m-health applications. A comparative performance analysis of the proposed approach is validated using the OPNET Modeler(®). The simulation results have shown an improved performance of resource allocation and end-to-end delay performance for typical medical video streaming application.

  8. Visibility vs. biomass in flowers: exploring corolla allocation in Mediterranean entomophilous plants.

    PubMed

    Herrera, Javier

    2009-05-01

    While pollinators may in general select for large, morphologically uniform floral phenotypes, drought stress has been proposed as a destabilizing force that may favour small flowers and/or promote floral variation within species. The general validity of this concept was checked by surveying a taxonomically diverse array of 38 insect-pollinated Mediterranean species. The interplay between fresh biomass investment, linear size and percentage corolla allocation was studied. Allometric relationships between traits were investigated by reduced major-axis regression, and qualitative correlates of floral variation explored using general linear-model MANOVA. Across species, flowers were perfectly isometrical with regard to corolla allocation (i.e. larger flowers were just scaled-up versions of smaller ones and vice versa). In contrast, linear size and biomass varied allometrically (i.e. there were shape variations, in addition to variations in size). Most floral variables correlated positively and significantly across species, except corolla allocation, which was largely determined by family membership and floral symmetry. On average, species with bilateral flowers allocated more to the corolla than those with radial flowers. Plant life-form was immaterial to all of the studied traits. Flower linear size variation was in general low among conspecifics (coefficients of variation around 10 %), whereas biomass was in general less uniform (e.g. 200-400 mg in Cistus salvifolius). Significant among-population differences were detected for all major quantitative floral traits. Flower miniaturization can allow an improved use of reproductive resources under prevailingly stressful conditions. The hypothesis that flower size reflects a compromise between pollinator attraction, water requirements and allometric constraints among floral parts is discussed.

  9. Factors Influencing the Use of Biomedical Health Care by Rural Bolivian Anemic Women: Structural Barriers, Reproductive Status, Gender Roles, and Concepts of Anemia

    PubMed Central

    Bedwell, Rebecca M.; Spielvogel, Hilde; Bellido, Diva

    2017-01-01

    The persistently high prevalence of anemia in rural highland Bolivia argues for targeted iron supplementation. We evaluated the cultural, structural and behavioral factors that may facilitate or impede an anemic woman's decision to secure this biomedical treatment from a rural Bolivian health center. Methods Non-pregnant women from a rural town and its surrounding region were tested for anemia. During phase 1 (n = 181), anemic women received a written recommendation for low-cost purchase of iron pills at the nearest health center. They were subsequently interviewed on their actions and experiences. Results Estimated anemia prevalence among these non-pregnant women was 50% higher than the national average. Despite holding conceptualizations of anemia generally aligned with biomedical concepts, only 40% of anemic women attempted to obtain iron supplements from the health center. Town residents were about twice as likely to attempt to purchase pills as outside-town residents. Town women who were concurrently breastfeeding and menstruating, considered anemia most serious for women, and considered family health the shared responsibility of spouses were most likely to decide to purchase iron pills. Age, education, or native language did not negatively influence this health care behavior. Conclusions Securing iron supplements involves individual trade-offs in the allocation of time, cost and effort. Nonetheless, suitably tailored programs can potentially harness local perceptions in the service of reducing anemia. Because of their comparatively high motivation to obtain iron supplements, targeting concurrently breastfeeding and menstruating women could have a positive cascade effect such that these women continue attending to their iron needs once they stop breastfeeding and if they become pregnant again. Because a sense of shared responsibility for family health appears to encourage women to attend to their own health, programs for women could involve their spouses. Complementing centralized availability, biomedical and traditional healers could distribute iron supplements on rotating visits to outlying areas and/or at highly attended weekly markets. PMID:28125636

  10. An overview on tritium permeation barrier development for WCLL blanket concept

    NASA Astrophysics Data System (ADS)

    Aiello, A.; Ciampichetti, A.; Benamati, G.

    2004-08-01

    The reduction of tritium permeation through blanket structural materials and cooling tubes has to be carefully evaluated to minimise radiological hazards. A strong effort has been made in the past to select the best technological solution for the realisation of tritium permeation barriers (TPB) on complex structures not directly accessible after the completion of the manufacturing process. The best solution was identified in aluminium rich coatings, which form Al 2O 3 at their surface. Two technologies were selected as reference for the realisation of coating in the WCLL blanket concept: the chemical vapour deposition (CVD) process developed on laboratory scale by CEA, and the hot dipping (HD) process developed by FZK. The results obtained during three years of tests on CVD and HD coated specimens in gas and liquid metal phase are summarised and discussed.

  11. Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project KDP-C Review

    NASA Technical Reports Server (NTRS)

    Grindle, Laurie; Sakahara, Robert; Hackenberg, Davis; Johnson, William

    2017-01-01

    The topics discussed are the UAS-NAS project life-cycle and ARMD thrust flow down, as well as the UAS environments and how we operate in those environments. NASA's Armstrong Flight Research Center at Edwards, CA, is leading a project designed to help integrate unmanned air vehicles into the world around us. The Unmanned Aircraft Systems Integration in the National Airspace System project, or UAS in the NAS, will contribute capabilities designed to reduce technical barriers related to safety and operational challenges associated with enabling routine UAS access to the NAS. The project falls under the Integrated Systems Research Program office managed at NASA Headquarters by the agency's Aeronautics Research Mission Directorate. NASA's four aeronautics research centers - Armstrong, Ames Research Center, Langley Research Center, and Glenn Research Center - are part of the technology development project. With the use and diversity of unmanned aircraft growing rapidly, new uses for these vehicles are constantly being considered. Unmanned aircraft promise new ways of increasing efficiency, reducing costs, enhancing safety and saving lives 460265main_ED10-0132-16_full.jpg Unmanned aircraft systems such as NASA's Global Hawks (above) and Predator B named Ikhana (below), along with numerous other unmanned aircraft systems large and small, are the prime focus of the UAS in the NAS effort to integrate them into the national airspace. Credits: NASA Photos 710580main_ED07-0243-37_full.jpg The UAS in the NAS project envisions performance-based routine access to all segments of the national airspace for all unmanned aircraft system classes, once all safety-related and technical barriers are overcome. The project will provide critical data to such key stakeholders and customers as the Federal Aviation Administration and RTCA Special Committee 203 (formerly the Radio Technical Commission for Aeronautics) by conducting integrated, relevant system-level tests to adequately address safety and operational challenges of national airspace access by unmanned aircraft systems, or UAS. In the process, the project will work with other key stakeholders to define necessary deliverables and products to help enable such access. Within the project, NASA is focusing on five sub-projects. These five focus areas include assurance of safe separation of unmanned aircraft from manned aircraft when flying in the national airspace; safety-critical command and control systems and radio frequencies to enable safe operation of UAS; human factors issues for ground control stations; airworthiness certification standards for UAS avionics and integrated tests and evaluation designed to determine the viability of emerging UAS technology. Five Focus Areas of the UAS Integration in the NAS Project Separation Assurance Provide an assessment of how planned Next Generation Air Transportation System (NextGen) separation assurance systems, with different functional allocations, perform for UAS in mixed operations with manned aircraft Assess the applicability to UAS and the performance of NASA NextGen separation assurance systems in flight tests with realistic latencies and uncertain trajectories Assess functional allocations ranging from today's ground-based, controller-provided aircraft separation to fully autonomous airborne self-separation Communications Develop data and rationale to obtain appropriate frequency spectrum allocations to enable safe and efficient operation of UAS in the NAS Develop and validate candidate secure safety-critical command and control system/subsystem test equipment for UAS that complies with UAS international/national frequency regulations, standards and recommended practices and minimum operational and aviation system performance standards for UAS Perform analysis to support recommendations for integration of safety-critical command and control systems and air traffic control communications to ensure safe and efficient operation of UAS in the NAS Human Systems Integration Develop a research test bed and database to provide data and proof of concept for GCS - ground control station - operations in the NAS Coordinate with standards organizations to develop human-factors guidelines for GCS operation in the NAS Certification Define a UAS classification scheme and approach to determining Federal Aviation Regulation airworthiness requirements applicable to all UAS digital avionics Provide hazard and risk-related data to support development of type design criteria and best development practices Integrated Tests and Evaluation Integrate and test mature concepts from technical elements to demonstrate and test viability Evaluate the performance of technology development in a relevant environment (full-mission, human-in-the-loop simulations and flight tests)

  12. Complexity Analysis and Algorithms for Optimal Resource Allocation in Wireless Networks

    DTIC Science & Technology

    2012-09-01

    independent orthogonal signaling such as OFDM . The general formulation will exploit the concept of ‘interference alignment’ which is known to provide...substantial rate gain over OFDM signalling for general interference channels. We have successfully analyzed the complexity to characterize the optimal...categories: PaperReceived Gennady Lyubeznik, Zhi-Quan Luo, Meisam Razaviyayn. On the degrees of freedom achievable through interference alignment in a MIMO

  13. USMC Logistics Resource Allocation Optimization Tool

    DTIC Science & Technology

    2015-12-01

    Virtual Warehouse Concept ..........................................12  3.  New Models in Logistics Network Design and Implications for Third Party...is the smallest DD activity in terms of manpower , but due to its proximity to USMC units, stocks a much greater quantity of USMC-demanded materiel...salient conclusion to reference with respect to this thesis. 12 2. Inventory Management of Repairables in the U.S. Marine Corps— A Virtual Warehouse

  14. Optimal plant nitrogen use improves model representation of vegetation response to elevated CO2

    NASA Astrophysics Data System (ADS)

    Caldararu, Silvia; Kern, Melanie; Engel, Jan; Zaehle, Sönke

    2017-04-01

    Existing global vegetation models often cannot accurately represent observed ecosystem behaviour under transient conditions such as elevated atmospheric CO2, a problem that can be attributed to an inflexibility in model representation of plant responses. Plant optimality concepts have been proposed as a solution to this problem as they offer a way to represent plastic plant responses in complex models. Here we present a novel, next generation vegetation model which includes optimal nitrogen allocation to and within the canopy as well as optimal biomass allocation between above- and belowground components in response to nutrient and water availability. The underlying hypothesis is that plants adjust their use of nitrogen in response to environmental conditions and nutrient availability in order to maximise biomass growth. We show that for two FACE (Free Air CO2 enrichment) experiments, the Duke forest and Oak Ridge forest sites, the model can better predict vegetation responses over the duration of the experiment when optimal processes are included. Specifically, under elevated CO2 conditions, the model predicts a lower optimal leaf N concentration as well as increased biomass allocation to fine roots, which, combined with a redistribution of leaf N between the Rubisco and chlorophyll components, leads to a continued NPP response under high CO2, where models with a fixed canopy stoichiometry predict a quick onset of N limitation.Existing global vegetation models often cannot accurately represent observed ecosystem behaviour under transient conditions such as elevated atmospheric CO2, a problem that can be attributed to an inflexibility in model representation of plant responses. Plant optimality concepts have been proposed as a solution to this problem as they offer a way to represent plastic plant responses in complex models. Here we present a novel, next generation vegetation model which includes optimal nitrogen allocation to and within the canopy as well as optimal biomass allocation between above- and belowground components in response to nutrient and water availability. The underlying hypothesis is that plants adjust their use of nitrogen in response to environmental conditions and nutrient availability in order to maximise biomass growth. We show that for two FACE (Free Air CO2 enrichment) experiments, the Duke forest and Oak Ridge forest sites, the model can better predict vegetation responses over the duration of the experiment when optimal processes are included. Specifically, under elevated CO2 conditions, the model predicts a lower optimal leaf N concentration as well as increased biomass allocation to fine roots, which, combined with a redistribution of leaf N between the Rubisco and chlorophyll components, leads to a continued NPP response under high CO2, where models with a fixed canopy stoichiometry predict a quick onset of N limitation.

  15. Reproductive success and failure: the role of winter body mass in reproductive allocation in Norwegian moose.

    PubMed

    Milner, Jos M; van Beest, Floris M; Solberg, Erling J; Storaas, Torstein

    2013-08-01

    A life history strategy that favours somatic growth over reproduction is well known for long-lived iteroparous species, especially in unpredictable environments. Risk-sensitive female reproductive allocation can be achieved by a reduced reproductive effort at conception, or the subsequent adjustment of investment during gestation or lactation in response to unexpected environmental conditions or resource availability. We investigated the relative importance of reduced investment at conception compared with later in the reproductive cycle (i.e. prenatal, perinatal or neonatal mortality) in explaining reproductive failure in two high-density moose (Alces alces) populations in southern Norway. We followed 65 multiparous, global positioning system (GPS)-collared females throughout the reproductive cycle and focused on the role of maternal nutrition during gestation in determining reproductive success using a quasi-experimental approach to manipulate winter forage availability. Pregnancy rates in early winter were normal (≥0.8) in all years while spring calving rates ranged from 0.4 to 0.83, with prenatal mortality accounting for most of the difference. Further losses over summer reduced autumn recruitment rates to 0.23-0.69, despite negligible predation. Over-winter mass loss explained variation in both spring calving and autumn recruitment success better than absolute body mass in early or late winter. Although pregnancy was related to body mass in early winter, overall reproductive success was unrelated to pre-winter body condition. We therefore concluded that reproductive success was limited by winter nutritional conditions. However, we could not determine whether the observed reproductive allocation adjustment was a bet-hedging strategy to maximise reproduction without compromising survival or whether females were simply unable to invest more resources in their offspring.

  16. Transgressive Shoreface Response in the Mississippi River DeltaShoreface Sediment Budget Influence on Barrier Island Evolution, Louisiana, USA

    NASA Astrophysics Data System (ADS)

    Beasley, B.; Georgiou, I. Y.; Miner, M. D.

    2017-12-01

    In Louisiana barrier islands are undergoing rapid morphological change due to shoreface retreat and increasing bay tidal prism driven by high rates of relative sea-level rise (RSLR) (1 cm/yr) and interior wetland loss, respectively. Previous works utilized historical region-scale bathymetry change and shoreline change analyses to assess large-scale coastal evolution. However, more localized assessments considering the role of sediment transport processes in regional evolution are lacking. This is essential to predicting coastal change trajectories and allocating limited sand resources for nourishment. Using historic bathymetric and shoreline data dating to the 1890s for the Louisiana coast, 100-m spaced shore-normal transects were created to track meter-scale elevation change for 1890, 1930, 1980, 2006, and 2015. An automated framework was used to quantify and track barrier island evolution parameters such as shoreline change, area, width, bathymetric contour migration, and shoreface slope. During the 125 yr analysis period, shoreline erosion mean rates slowed from 12 to 6 m/yr while lower shoreface migration mean rates increased from 5 to 25 m/yr. Locally, retreat rates for the Caminada Headland upper shoreface slowed from 18 to 8 m/yr while lower shoreface retreat rates increased from 8 to 14m/yr. The Timbalier Islands experienced increased migration rates along the entire shoreface, while the lower shoreface of the Isles Dernieres transitioned from progradational to erosional (-5 m/yr in 1890 to 20 m/yr in 2006). Our analysis suggests that although shoreline erosion rates decreased, overall landward migration of the barrier system increased as the shoreface steepened. Our results illustrate that monitoring subaerial island erosion rates are insufficient for evaluating regional dynamics of transgressive coastal systems. The longevity of barriers appears diminished due to a reduction in the shoreface sediment available and further corroborates the role of the shoreface on barrier island evolution. Advances in understanding these processes will facilitate more informed planning, management, and mitigation of transgressive barrier islands.

  17. Managers' experience of success criteria and barriers to implementing mobile radiography services in nursing homes in Norway: a qualitative study.

    PubMed

    Kjelle, Elin; Lysdahl, Kristin Bakke; Olerud, Hilde Merete; Myklebust, Aud Mette

    2018-04-25

    In order to meet the future challenges posed by ageing populations, new technology, telemedicine and a more personalized healthcare system are needed. Earlier research has shown mobile radiography services to be highly beneficial for nursing home residents in addition to being cost-effective. Despite the benefits, mobile radiography services are uncommon in Europe and Norway. The purpose of this study was to explore success criteria and barriers in the process of implementing mobile radiography services, from the point of view of the hospital and municipal managers. Eleven semi-structured interviews were conducted with managers from five hospitals and six municipalities in Norway where mobile radiography services had been implemented. Core issues in the interview guide were barriers and facilitators in the different phases of implementation. The framework method for thematic analysis was used for analysing the data inductively in a research team. Five main categories were developed through the success criteria and barriers experienced by the participants: national health policy, regional and municipal policy and conditions, inter-organizational implementation projects, experienced outcome, and professional skills and personal characteristics. The categories were allocated into three higher-order classifications: macro, meso and micro levels. The main barriers experienced by the managers were financial, procedural and structural. In particular, the reimbursement system, lack of management across healthcare levels and the lack of compatible information systems acted as barriers. The main facilitators were external funding, enthusiastic individuals in the organizations and good collaboration between hospitals and municipalities. The managers experienced financial, structural and procedural barriers. The main success criteria in the process were external funding, and the support and engagement from the individuals in the organizations. This commitment was mainly facilitated by the intuitive appeal of mobile radiography. Changes in healthcare management and in the financial system might facilitate services across healthcare levels. In addition, compatible information systems across healthcare levels are needed in order to facilitate the use of new technology and mobile services.

  18. Performance of distributed bagged stone dust barrier in combating coal-dust explosions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Plessis, J.J.L. du; Vassard, P.S.

    1999-07-01

    The Kloppersbos Research Facility of the CSIR's Division of Mining Technology has developed a new method of building stone dust barriers. The new barrier makes use of a previous concept of containing stone dust in a bag, but incorporates a new method of rupturing the bag. This was achieved by adapting the closing mechanism and by balancing the stone dust content with the void in the bag. The bagged barrier was extensively tested in the 200-m test gallery. During these tests, it became evident that these bags could be made to rupture and spread stone dust when subjected to smallermore » forces than those required for the most commonly used passive barrier, the Polish light barrier. To validate this, as well as to gain international acceptance of this new barrier, tests were conducted in the German experimental mine, DMT Tremonia, Dortmund. The barrier was evaluated against numerous methane-initiated coal-dust explosions. The paper describes the successful inhibition of coal-dust explosions at Kloppersbos and DMT tremonia. The barrier has been proven successfully for static pressures of 44 to 82 kpa, dynamic pressures of 12 to 36 kpa and for flame speeds as low as 23 m/s. This barrier is now accepted by the South African government and has been implemented in numerous South African collieries.« less

  19. Phase 0 and phase III transport in various organs: combined concept of phases in xenobiotic transport and metabolism.

    PubMed

    Döring, Barbara; Petzinger, Ernst

    2014-08-01

    The historical phasing concept of drug metabolism and elimination was introduced to comprise the two phases of metabolism: phase I metabolism for oxidations, reductions and hydrolyses, and phase II metabolism for synthesis. With this concept, biological membrane barriers obstructing the accessibility of metabolism sites in the cells for drugs were not considered. The concept of two phases was extended to a concept of four phases when drug transporters were detected that guided drugs and drug metabolites in and out of the cells. In particular, water soluble or charged drugs are virtually not able to overcome the phospholipid membrane barrier. Drug transporters belong to two main clusters of transporter families: the solute carrier (SLC) families and the ATP binding cassette (ABC) carriers. The ABC transporters comprise seven families with about 20 carriers involved in drug transport. All of them operate as pumps at the expense of ATP splitting. Embedded in the former phase concept, the term "phase III" was introduced by Ishikawa in 1992 for drug export by ABC efflux pumps. SLC comprise 52 families, from which many carriers are drug uptake transporters. Later on, this uptake process was referred to as the "phase 0 transport" of drugs. Transporters for xenobiotics in man and animal are most expressed in liver, but they are also present in extra-hepatic tissues such as in the kidney, the adrenal gland and lung. This review deals with the function of drug carriers in various organs and their impact on drug metabolism and elimination.

  20. Gastric cancer-derived exosomes promote peritoneal metastasis by destroying the mesothelial barrier.

    PubMed

    Deng, Guang; Qu, Jinglei; Zhang, Ye; Che, Xiaofang; Cheng, Yu; Fan, Yibo; Zhang, Simeng; Na, Di; Liu, Yunpeng; Qu, Xiujuan

    2017-07-01

    An intact mesothelium serves as a protective barrier to inhibit peritoneal carcinomatosis. Cancer-derived exosomes can mediate directional tumor metastasis; however, little is known about whether gastric cancer-derived exosomes will destroy the mesothelial barrier and promote peritoneal dissemination. Here, we demonstrate that gastric cancer-derived exosomes facilitate peritoneal metastasis by causing mesothelial barrier disruption and peritoneal fibrosis. Injury of peritoneal mesothelial cells elicited by gastric cancer-derived exosomes is through concurrent apoptosis and mesothelial-to-mesenchymal transition (MMT). Additionally, upregulation of p-ERK in peritoneal mesothelial cells is primarily responsible for the MMT while contributing little to apoptosis. Together, these data support the concept that exosomes play a crucial role in remodeling the premetastatic microenvironment and identify a novel mechanism for peritoneal metastasis of gastric carcinoma. © 2017 Federation of European Biochemical Societies.

  1. Modeling the Dynamics of Task Allocation and Specialization in Honeybee Societies

    NASA Astrophysics Data System (ADS)

    Hoogendoorn, Mark; Schut, Martijn C.; Treur, Jan

    The concept of organization has been studied in sciences such as social science and economics, but recently also in artificial intelligence [Furtado 2005, Giorgini 2004, and McCallum 2005]. With the desire to analyze and design more complex systems consisting of larger numbers of agents (e.g., in nature, society, or software), the need arises for a concept of higher abstraction than the concept agent. To this end, organizational modeling is becoming a practiced stage in the analysis and design of multi-agent systems, hereby taking into consideration the environment of the organization. An environment can have a high degree of variability which might require organizations to adapt to the environment's dynamics, to ensure a continuous proper functioning of the organization. Hence, such change processes are a crucial function of the organization and should be part of the organizational model.

  2. Against Modernity: Gandhi and Adult Education.

    ERIC Educational Resources Information Center

    Steele, Tom; Taylor, Richard

    1994-01-01

    Gandhi's conception of basic education was spiritual and holistic, in contrast to Western-inspired vocationalism. The incorporation of his craft-based system into the nationalist agenda perpetuated the class barriers he was trying to dissolve. (SK)

  3. Testing Map Features Designed to Convey the Uncertainty of Cancer Risk: Insights Gained From Assessing Judgments of Information Adequacy and Communication Goals

    PubMed Central

    Severtson, Dolores J.

    2015-01-01

    Barriers to communicating the uncertainty of environmental health risks include preferences for certain information and low numeracy. Map features designed to communicate the magnitude and uncertainty of estimated cancer risk from air pollution were tested among 826 participants to assess how map features influenced judgments of adequacy and the intended communication goals. An uncertain versus certain visual feature was judged as less adequate but met both communication goals and addressed numeracy barriers. Expressing relative risk using words communicated uncertainty and addressed numeracy barriers but was judged as highly inadequate. Risk communication and visual cognition concepts were applied to explain findings. PMID:26412960

  4. Testing Map Features Designed to Convey the Uncertainty of Cancer Risk: Insights Gained From Assessing Judgments of Information Adequacy and Communication Goals.

    PubMed

    Severtson, Dolores J

    2015-02-01

    Barriers to communicating the uncertainty of environmental health risks include preferences for certain information and low numeracy. Map features designed to communicate the magnitude and uncertainty of estimated cancer risk from air pollution were tested among 826 participants to assess how map features influenced judgments of adequacy and the intended communication goals. An uncertain versus certain visual feature was judged as less adequate but met both communication goals and addressed numeracy barriers. Expressing relative risk using words communicated uncertainty and addressed numeracy barriers but was judged as highly inadequate. Risk communication and visual cognition concepts were applied to explain findings.

  5. Utilitarianism, poverty and development of disabled people.

    PubMed

    Xavier de França, Inacia Sátiro; Freitag Pagliuca, Lorita Marlena

    2007-01-01

    This study aims to analyze the influences of human development factors in the experience of disabled people based on social scenarios of inequality. The data collected were standardized and allocated in thematic categories. The analysis was based on liberal utilitarianism. The conclusion is that there is legislation in Brazil that guarantees the disabled people's development in areas such as health, education and work. However despite the attempts of decision makers in combating discriminatory behaviors and the theory based on equity, these people still face difficulties in breaking the barrier of poverty and achieving all humans rights deserved.

  6. Advances in the Dynallax solid-state dynamic parallax barrier autostereoscopic visualization display system.

    PubMed

    Peterka, Tom; Kooima, Robert L; Sandin, Daniel J; Johnson, Andrew; Leigh, Jason; DeFanti, Thomas A

    2008-01-01

    A solid-state dynamic parallax barrier autostereoscopic display mitigates some of the restrictions present in static barrier systems, such as fixed view-distance range, slow response to head movements, and fixed stereo operating mode. By dynamically varying barrier parameters in real time, viewers may move closer to the display and move faster laterally than with a static barrier system, and the display can switch between 3D and 2D modes by disabling the barrier on a per-pixel basis. Moreover, Dynallax can output four independent eye channels when two viewers are present, and both head-tracked viewers receive an independent pair of left-eye and right-eye perspective views based on their position in 3D space. The display device is constructed by using a dual-stacked LCD monitor where a dynamic barrier is rendered on the front display and a modulated virtual environment composed of two or four channels is rendered on the rear display. Dynallax was recently demonstrated in a small-scale head-tracked prototype system. This paper summarizes the concepts presented earlier, extends the discussion of various topics, and presents recent improvements to the system.

  7. Skin sparing/skin reducing mastectomy (SSM/SRM) and the concept of oncoplastic breast surgery.

    PubMed

    Atiyeh, Bishara; Dibo, Saad; Zgheib, Elias; Abbas, Jaber

    2014-10-01

    With the better understanding of breast cancer history and biology, improved diagnostic modalities and the shift towards minimally invasive surgeries, indications for prophylactic mastectomy, skin sparing or skin reducing mastectomies (SSM/SRM) with nipple areolar complex (NAC) preservation coupled with immediate breast reconstruction are gaining popularity. The authors share their experience and conception with mastectomy and immediate alloplastic breast reconstruction with the esthetic circumvertical mammoplasty pattern combined with the dermal barrier buttress flap. The described technique was performed for 28 patients presenting for mastectomy and immediate alloplastic breast reconstruction. With close collaboration between the oncologic and plastic surgeons, mastectomy was performed in all cases with the esthetic circumvertical mammoplasty pattern. To achieve safe excision and optimal reconstruction, the standard incisions could be custom designed to fit oncologic requirements and allow the creation of a dermal barrier flap used as a buttress separating the implant from the suture line. The circumvertical mastectomy pattern combined with the dermal barrier buttress flap is a versatile option allowing safe reconstruction regardless of the tumor and necessary skin excision location. Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

  8. UAS Integration into the NAS Project

    NASA Technical Reports Server (NTRS)

    Bauer, Jeff

    2010-01-01

    The goal of the UAS Integration in the NAS Project is to contribute capabilities that reduce technical barriers related to the safety and operational challenges associated with enabling routine UAS access to the NAS This goal will be accomplished through a two-phased approach of system-level integration of key concepts, technologies and/or procedures, and demonstrations of integrated capabilities in an operationally relevant environment. Technical objectives include: PHASE 1: a) Validating the key technical areas identified by this project. System-level analyses, a State of the Art Analysis (SOAA), and a ConOps will identify the challenges and barriers preventing routine UAS access to the NAS. b) Developing a national roadmap and gap analysis identifying specific deliverables in the area of operations, procedures, and technologies that will impact future policy decisions. PHASE 2: a) Provide regulators with a methodology for developing airworthiness requirements for UAS and data to support development of certifications standards and regulatory guidance. b) Provide systems-level integrated testing of concepts and/or capabilities that address barriers to routine access to the NAS. Through simulation and flight testing, address issues including separation assurance, communications requirements, and Pilot Aircraft Interfaces (PAIs) in operationally relevant environments

  9. Understanding and Addressing Socio-Cultural Barriers to Medical Male Circumcision in Traditionally Non-Circumcising Rural Communities in Sub-Saharan Africa

    PubMed Central

    Khumalo-Sakutukwa, Gertrude; Lane, Tim; van-Rooyen, Heidi; Chingono, Alfred; Humphries, Hilton; Timbe, Andrew; Fritz, Katherine; Chirowodza, Admire; Morin, Stephen F.

    2013-01-01

    Given the success of recent clinical trials establishing the safety and efficacy of adult medical male circumcision in Africa, attention has now shifted to barriers and facilitators to programmatic implementation in traditionally non-circumcising communities. In this study, we attempted to develop a fuller understanding of the role of cultural issues in the acceptance of adult circumcision. We conducted four focus group discussions with 28 participants in Mutoko in Zimbabwe, and 33 participants in Vulindlela, in KwaZulu-Natal, South Africa, as well as 19 key informant interviews in both settings. We found the concept of male circumcision to be an alien practice, particularly as expressed in the context of local languages. Cultural barriers included local concepts of ethnicity, social groups, masculinity, and sexuality. On the other hand, we found that concerns about the impact of HIV on communities resulted in willingness to consider adult male circumcision as an option if it would result in lowering the local burden of the epidemic. Adult medical male circumcision promotional messages that create a synergy between understandings of both traditional and medical circumcision will be more successful in these communities. PMID:23815101

  10. One health in Switzerland: a visionary concept at a crossroads?

    PubMed

    Meisser, Andrea; Schelling, Esther; Zinsstag, Jakob

    2011-05-13

    One Health stands for the health of humans, animals and the environment. There is only one health in our entire ecosystem, and the equation for its promotion is in interdisciplinary cooperation. One Health benefits from synergies to generate added value and is a promising strategy to strengthen health systems. A growing number of One Health conferences worldwide bear witness to a spirit of optimism which should result in the implementation of a sustainable One Health policy globally, regionally, nationally and locally. The purpose of this study was to investigate the opportunities for implementation of the One Health concept in Switzerland. Between April and August 2010, semi-structured face-to-face interviews were conducted with 16 key experts selected from among the leading personalities in the Swiss health system. The experts confirmed the potential of the One Health concept for Switzerland. Barriers such as cultural differences, absence of evidence, federal structures and a relatively low degree of suffering were identified and a road map established, including research activities, capacity-building and a stakeholder approach to joint preparation and tailored implementation of the One Health concept in Switzerland. These data suggest that One Health can support the opinion leaders in their quest for solutions. The detailed and unbiased description of potential barriers and a clear guide for a step-by-step action plan represent suggestions for a realistic way forward. Experience gained and lessons learnt in Switzerland may be of interest to other countries and help communicate and promote the One Health concept.

  11. Saltwater-barrier line in Florida : concepts, considerations, and site examples

    USGS Publications Warehouse

    Hughes, Jerry L.

    1979-01-01

    Construction of canals and enlargement of streams in Florida has been mostly to alleviate impact of floods and to drain wetlands for development. Land drainage and heavy pumpage from coastal water-table aquifers has degraded potable ground and surface water with saltwater. Control of saltwater intrusion is possible through implementation of certain hydrologic principles. State of Florida statute 373.033 provides for a saltwater-barrier line in areas of saltwater intrusion along canals. A saltwater-barrier line is defined as the allowable landward limit that a canal shall be constructed or enlarged or a stream deepened or enlarged without a salinity-control structure seaward of the saltwater-barrier line. The salinity control structure controls saltwater intrusion along a surface-water channel and assists in controlling saltwater intrusion into shallow aquifers. This report briefly reviews the fundamentals of saltwater intrusion in surface-water channels and associated coastal aquifers, describes the effects of established saltwater-barrier lines in Florida, and gives a history of the use and benefits of salinity-control structures. (Woodard-USGS).

  12. Reconsolidated Salt as a Geotechnical Barrier

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hansen, Francis D.; Gadbury, Casey

    Salt as a geologic medium has several attributes favorable to long-term isolation of waste placed in mined openings. Salt formations are largely impermeable and induced fractures heal as stress returns to equilibrium. Permanent isolation also depends upon the ability to construct geotechnical barriers that achieve nearly the same high-performance characteristics attributed to the native salt formation. Salt repository seal concepts often include elements of reconstituted granular salt. As a specific case in point, the Waste Isolation Pilot Plant recently received regulatory approval to change the disposal panel closure design from an engineered barrier constructed of a salt-based concrete to onemore » that employs simple run-of-mine salt and temporary bulkheads for isolation from ventilation. The Waste Isolation Pilot Plant is a radioactive waste disposal repository for defense-related transuranic elements mined from the Permian evaporite salt beds in southeast New Mexico. Its approved shaft seal design incorporates barrier components comprising salt-based concrete, bentonite, and substantial depths of crushed salt compacted to enhance reconsolidation. This paper will focus on crushed salt behavior when applied as drift closures to isolate disposal rooms during operations. Scientific aspects of salt reconsolidation have been studied extensively. The technical basis for geotechnical barrier performance has been strengthened by recent experimental findings and analogue comparisons. The panel closure change was accompanied by recognition that granular salt will return to a physical state similar to the halite surrounding it. Use of run-of-mine salt ensures physical and chemical compatibility with the repository environment and simplifies ongoing disposal operations. Our current knowledge and expected outcome of research can be assimilated with lessons learned to put forward designs and operational concepts for the next generation of salt repositories. Mined salt repositories have the potential to isolate permanently vast inventories of radioactive and hazardous wastes.« less

  13. Lightweight Shield Against Space Debris

    NASA Technical Reports Server (NTRS)

    Redmon, John W., Jr.; Lawson, Bobby E.; Miller, Andre E.; Cobb, W. E.

    1992-01-01

    Report presents concept for lightweight, deployable shield protecting orbiting spacecraft against meteoroids and debris, and functions as barrier to conductive and radiative losses of heat. Shield made in four segments providing 360 degree coverage of cylindrical space-station module.

  14. Marketing the 'Sex Check': evaluating recruitment strategies for a telephone-based HIV prevention project for gay and bisexual men.

    PubMed

    McKee, Michael B; Picciano, Joseph F; Roffman, Roger A; Swanson, Fred; Kalichman, Seth C

    2006-04-01

    Designing effective marketing and recruitment strategies for HIV prevention research requires attention to cultural relevance, logistical barriers, and perceived psychosocial barriers to accessing services. McGuire's communication/persuasion matrix (1985) guided our evaluation, with particular attention to success of each marketing "channel" (i.e., strategy) vis-à-vis the number of all callers, eligible callers, and enrolled callers, as well as reaching so-called "hard-to-serve" individuals. Nearly all channels offered success in reaching specific subgroups. Latinos responded favorably to posters, bisexuals responded favorably to paid media in an alternative (non-gay) publication, and precontemplators responded to referrals by family and friends. Although multiple recruitment strategies were used, three were crucial to the success of the project: (a) recruiters' presence in gay venues, (b) referrals by family and friends (snowball technique), and (c) paid advertisements in alternative (non-gay) local newspapers. Resource allocation and costs are also presented for each channel.

  15. Moving toward universal coverage of health insurance in Vietnam: barriers, facilitating factors, and lessons from Korea.

    PubMed

    Do, Ngan; Oh, Juhwan; Lee, Jin-Seok

    2014-07-01

    Vietnam has pursued universal health insurance coverage for two decades but has yet to fully achieve this goal. This paper investigates the barriers to achieve universal coverage and examines the validity of facilitating factors to shorten the transitional period in Vietnam. A comparative study of facilitating factors toward universal coverage of Vietnam and Korea reveals significant internal forces for Vietnam to further develop the National Health Insurance Program. Korea in 1977 and Vietnam in 2009 have common characteristics to be favorable of achieving universal coverage with similarities of level of income, highly qualified administrative ability, tradition of solidarity, and strong political leadership although there are differences in distribution of population and structure of the economy. From a comparative perspective, Vietnam can consider the experience of Korea in implementing the mandatory enrollment approach, household unit of eligibility, design of contribution and benefit scheme, and resource allocation to health insurance for sustainable government subsidy to achieve and sustain the universal coverage of health insurance.

  16. System Engineering the Space Infrared Interferometric Telescope (SPIRIT)

    NASA Technical Reports Server (NTRS)

    Hyde, Tristram T.; Leisawitz, David T.; Rinehart, Stephen

    2007-01-01

    The Space Infrared Interferometric Telescope (SPIRIT) was designed to accomplish three scientific objectives: (1) learn how planetary systems form from protostellar disks and how they acquire their inhomogeneous chemical composition; (2) characterize the family of extrasolar planetary systems by imaging the structure in debris disks to understand how and where planets of different types form; and (3) learn how high-redshift galaxies formed and merged to form the present-day population of galaxies. SPIRIT will accomplish these objectives through infrared observations with a two aperture interferometric instrument. This paper gives an overview of SPIRIT design and operation, and how the three design cycle concept study was completed. The error budget for several key performance values allocates tolerances to all contributing factors, and a performance model of the spacecraft plus instrument system demonstrates meeting those allocations with margin.

  17. Stratum variance estimation for sample allocation in crop surveys. [Great Plains Corridor

    NASA Technical Reports Server (NTRS)

    Perry, C. R., Jr.; Chhikara, R. S. (Principal Investigator)

    1980-01-01

    The problem of determining stratum variances needed in achieving an optimum sample allocation for crop surveys by remote sensing is investigated by considering an approach based on the concept of stratum variance as a function of the sampling unit size. A methodology using the existing and easily available information of historical crop statistics is developed for obtaining initial estimates of tratum variances. The procedure is applied to estimate stratum variances for wheat in the U.S. Great Plains and is evaluated based on the numerical results thus obtained. It is shown that the proposed technique is viable and performs satisfactorily, with the use of a conservative value for the field size and the crop statistics from the small political subdivision level, when the estimated stratum variances were compared to those obtained using the LANDSAT data.

  18. Intelligent energy allocation strategy for PHEV charging station using gravitational search algorithm

    NASA Astrophysics Data System (ADS)

    Rahman, Imran; Vasant, Pandian M.; Singh, Balbir Singh Mahinder; Abdullah-Al-Wadud, M.

    2014-10-01

    Recent researches towards the use of green technologies to reduce pollution and increase penetration of renewable energy sources in the transportation sector are gaining popularity. The development of the smart grid environment focusing on PHEVs may also heal some of the prevailing grid problems by enabling the implementation of Vehicle-to-Grid (V2G) concept. Intelligent energy management is an important issue which has already drawn much attention to researchers. Most of these works require formulation of mathematical models which extensively use computational intelligence-based optimization techniques to solve many technical problems. Higher penetration of PHEVs require adequate charging infrastructure as well as smart charging strategies. We used Gravitational Search Algorithm (GSA) to intelligently allocate energy to the PHEVs considering constraints such as energy price, remaining battery capacity, and remaining charging time.

  19. Global Sensor Management: Military Asset Allocation

    DTIC Science & Technology

    2009-10-06

    solution (referred to as moves). A similar approach has been suggested by Zweben et al. (1993), who use a local search base metaheuristic , specifically...trapped in a local optimum. Hansen and Mladenovic (1998) describe the concept of variable neighborhood local search algorithms , and describe an...Mataric and G.S. Sukhatme (2002). “An incremental deployment algorithm for mobile robot teams,” Proceedings of the 2002 IEEE/RSJ Intl. Conference on

  20. Role Allocation and Team Structure in Command and Control Teams

    DTIC Science & Technology

    2014-06-01

    organizational psychology and management sciences literature show concepts such as empowered self-management and self-regulating work teams (see Cooney, 2004...tankers (FT), search units (S) and rescue units (R). Each unit is represented on the map by a numbered icon. Each type of unit is colour -coded and...Understanding team adaptation: A conceptual analysis and model. Journal of Applied Psychology , 91, 1189-1207. Cannon-Bowers, J. A., Tannenbaum

  1. Intra-household allocation of food and health care: current findings and understandings--introduction.

    PubMed

    Messer, E

    1997-06-01

    This work offers an anthropological analysis of intra-household processes underlying gender- and age-specific differences in individual nutritional and health care allocations and outcomes in particular cultures. Based on recent ethnographic studies in India, Nepal, Madagascar, Mexico, and Peru, correspondences are analyzed between local cultural ("emic") and scientist-policy maker practitioner ("etic") understandings of nutrition, health, and human development, and the relative "values" of females, males, and children of different ages. The data and analyses clarify specific epidemiological and demographic findings on age and gender bias in nutrition and health and highlight the multiple cultural, economic, and biological factors that contribute to gender- or age-based discrimination or neglect. Recent advances in nutrition policy have argued for a broader concept of nutritional security, one that incorporates both food quantity and quality, and of nutrition as "food, health and care" (International Conference on Nutrition, World Declaration and Plan of Action for Nutrition, FAO/WHO, Rome, 1992). These ethnographic findings; lend strong support for such broader nutrition concepts and associated nutrition policies. The studies also suggest ways in which anthropological questions, methods, and data and community-based research can help predict or identify the nutritionally vulnerable within households and help other social and medical scientists design more effective interventions.

  2. Eradicating Barriers to Mental Health Care Through Integrated Service Models: Contemporary Perspectives for Psychiatric-Mental Health Nurses.

    PubMed

    Ellis, Horace; Alexander, Vinette

    2016-06-01

    There has been renewed, global interest in developing new and transformative models of facilitating access to high-quality, cost-effective, and individually-centered health care for severe mentally-ill (SMI) persons of diverse racial/ethnic, cultural and socioeconomic backgrounds. However, in our present-day health-service delivery systems, scholars have identified layers of barriers to widespread dispersal of well-needed mental health care both nationally and internationally. It is crucial that contemporary models directed at eradicating barriers to mental health services are interdisciplinary in context, design, scope, sequence, and best-practice standards. Contextually, nurses are well-positioned to influence the incorporation and integration of new concepts into operationally interdisciplinary, evidence-based care models with measurable outcomes. The aim of this concept paper is to use the available evidence to contextually explicate how the blended roles of psychiatric mental health (PMH) nursing can be influential in eradicating barriers to care and services for SMI persons through the integrated principles of collaboration, integration and service expansion across health, socioeconomic, and community systems. A large body of literature proposes that any best-practice standards aimed at eliminating barriers to the health care needs of SMI persons require systematic, well-coordinated interdisciplinary partnerships through evidence-based, high-quality, person-centered, and outcome-driven processes. Transforming the conceptual models of collaboration, integration and service expansion could be revolutionary in how care and services are coordinated and dispersed to populations across disadvantaged communities. Building on their longstanding commitment to individual and community care approaches, and their pivotal roles in research, education, leadership, practice, and legislative processes; PMH nurses are well-positioned to be both influential and instrumental in the development of innovative, revolutionary, and transformative paradigmatic models aimed at eradicating treatment barriers, promoting well-being, and reducing preventable mortalities and morbidities among SMI persons. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Perception of Barriers to the Diagnosis and Receipt of Treatment for Neuropsychiatric Disturbances After Traumatic Brain Injury.

    PubMed

    Albrecht, Jennifer S; O'Hara, Lyndsay M; Moser, Kara A; Mullins, C Daniel; Rao, Vani

    2017-12-01

    To explore perceptions of barriers and facilitators to the diagnosis and receipt of treatment for neuropsychiatric disturbances (NPDs) after traumatic brain injury (TBI). Qualitative study using semistructured interviews and focus groups. A clinic specializing in the treatment of TBI NPDs, an urban trauma center, and a large urban academic hospital. A sample (N=33) of health care providers (n=10) who treat individuals with TBI, persons with TBI (n=18), and caregivers (n=5). Not applicable. Topic guides for the interviews and focus groups were guided by previous literature, clinical experience, and the goals of the project and focused on the 3 most common TBI NPDs: depression, anxiety, and posttraumatic stress disorder. The interviews and focus groups were audio-recorded and transcribed verbatim. We performed a conventional content analysis on the transcripts and grouped concepts into overall themes, incorporating feedback from stakeholders. Patient education, insurance, provider type, time since TBI, caregiver support, and recognition or screening for TBI NPDs were the most frequently mentioned barriers or facilitators to the diagnosis and treatment of TBI NPDs by both interview and focus group participants. We grouped these and other frequently mentioned concepts into 3 broad themes: education, access, and support. Each of these themes is explored in depth and supported with direct quotations. This study explored patient, caregiver, and health care provider and identified barriers and facilitators to the diagnosis and receipt of treatment for TBI NPDs. Barriers included poor provider education on TBI NPDs and limited access to care due to lack of insurance, transportation, and income. Facilitators included patient education on TBI NPDs and strong caregiver support. Future studies should develop and pilot interventions aimed at quality of care that address the identified barriers and facilitators. Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  4. NASA's Evolution to K(sub a)- Band Space Communications for Near-Earth Spacecraft

    NASA Technical Reports Server (NTRS)

    McCarthy, Kevin P.; Stocklin, Frank J.; Geldzahler, Barry J.; Friedman, Daniel E.; Celeste, Peter B.

    2010-01-01

    Over the next several years, NASA plans to launch multiple earth-science missions which will send data from low-Earth orbits to ground stations at 1-3 Gbps, to achieve data throughputs of 5-40 terabits per day. These transmission rates exceed the capabilities of S-band and X-band frequency allocations used for science probe downlinks in the past. Accordingly, NASA is exploring enhancements to its space communication capabilities to provide the Agency's first Ka-band architecture solution for next generation missions in the near-earth regime. This paper describes the proposed Ka-band solution's drivers and concept, constraints and analyses which shaped that concept, and expansibility for future needs

  5. Mechanisms underlying comprehension of health information in adulthood: the roles of prior knowledge and working memory capacity.

    PubMed

    Soederberg Miller, Lisa M; Gibson, Tanja N; Applegate, Elizabeth A; de Dios, Jeannette

    2011-07-01

    Prior knowledge, working memory capacity (WMC), and conceptual integration (attention allocated to integrating concepts in text) are critical within many contexts; however, their impact on the acquisition of health information (i.e. learning) is relatively unexplored.We examined how these factors impact learning about nutrition within a cross-sectional study of adults ages 18 to 81. Results showed that conceptual integration mediated the effects of knowledge and WMC on learning, confirming that attention to concepts while reading is important for learning about health. We also found that when knowledge was controlled, age declines in learning increased, suggesting that knowledge mitigates the effects of age on learning about nutrition.

  6. The role of organizational structure in readiness for change: A conceptual integration.

    PubMed

    Benzer, Justin K; Charns, Martin P; Hamdan, Sami; Afable, Melissa

    2017-02-01

    The purpose of this review is to extend extant conceptualizations of readiness for change as an individual-level phenomenon. This review-of-reviews focuses on existing conceptual frameworks from the dissemination, implementation, quality improvement, and organizational transformation literatures in order to integrate theoretical rationales for how organization structure, a key dimension of the organizational context, may impact readiness for change. We propose that the organization structure dimensions of differentiation and integration impact readiness for change at the individual level of analysis by influencing four key concepts of relevance, legitimacy, perceived need for change, and resource allocation. We identify future research directions that focus on these four key concepts.

  7. Tailored interventions to overcome identified barriers to change: effects on professional practice and health care outcomes

    PubMed Central

    Baker, Richard; Camosso-Stefinovic, Janette; Gillies, Clare; Shaw, Elizabeth J; Cheater, Francine; Flottorp, Signe; Robertson, Noelle

    2014-01-01

    Background In the previous version of this review, the effectiveness of interventions tailored to barriers to change was found to be uncertain. Objectives To assess the effectiveness of interventions tailored to address identified barriers to change on professional practice or patient outcomes. Search methods For this update, in addition to the EPOC Register and pending files, we searched the following databases without language restrictions, from inception until August 2007: MEDLINE, EMBASE, CINAHL, BNI and HMIC. We searched the National Research Register to November 2007. We undertook further searches to October 2009 to identify potentially eligible published or ongoing trials. Selection criteria Randomised controlled trials (RCTs) of interventions tailored to address prospectively identified barriers to change that reported objectively measured professional practice or healthcare outcomes in which at least one group received an intervention designed to address prospectively identified barriers to change. Data collection and analysis Two reviewers independently assessed quality and extracted data. We undertook quantitative and qualitative analyses. The quantitative analyses had two elements. We carried out a meta-regression to compare interventions tailored to address identified barriers to change with either no interventions or an intervention(s) not tailored to the barriers.We carried out heterogeneity analyses to investigate sources of differences in the effectiveness of interventions. These included the effects of: risk of bias, concealment of allocation, rigour of barrier analysis, use of theory, complexity of interventions, and the reported presence of administrative constraints. Main results We included 26 studies comparing an intervention tailored to address identified barriers to change to no intervention or an intervention(s) not tailored to the barriers. The effect sizes of these studies varied both across and within studies. Twelve studies provided enough data to be included in the quantitative analysis. A meta-regression model was fitted adjusting for baseline odds by fitting it as a covariate, to obtain the pooled odds ratio of 1.54 (95% CI, 1.16 to 2.01) from Bayesian analysis and 1.52 (95% CI, 1.27 to 1.82, P < 0.001) from classical analysis. The heterogeneity analyses found that no study attributes investigated were significantly associated with effectiveness of the interventions. Authors’ conclusions Interventions tailored to prospectively identified barriers are more likely to improve professional practice than no intervention or dissemination of guidelines. However, the methods used to identify barriers and tailor interventions to address them need further development. Research is required to determine the effectiveness of tailored interventions in comparison with other interventions. PMID:20238340

  8. Subacute stress and chronic stress interact to decrease intestinal barrier function in rats.

    PubMed

    Lauffer, Adriana; Vanuytsel, Tim; Vanormelingen, Christophe; Vanheel, Hanne; Salim Rasoel, Shadea; Tóth, Joran; Tack, Jan; Fornari, Fernando; Farré, Ricard

    2016-01-01

    Psychological stress increases intestinal permeability, potentially leading to low-grade inflammation and symptoms in functional gastrointestinal disorders. We assessed the effect of subacute, chronic and combined stress on intestinal barrier function and mast cell density. Male Wistar rats were allocated to four experimental groups (n = 8/group): 1/sham; 2/subacute stress (isolation and limited movement for 24 h); 3/chronic crowding stress for 14 days and 4/combined subacute and chronic stress. Jejunum and colon were collected to measure: transepithelial electrical resistance (TEER; a measure of epithelial barrier function); gene expression of tight junction molecules; mast cell density. Plasma corticosterone concentration was increased in all three stress conditions versus sham, with highest concentrations in the combined stress condition. TEER in the jejunum was decreased in all stress conditions, but was significantly lower in the combined stress condition than in the other groups. TEER in the jejunum correlated negatively with corticosterone concentration. Increased expression of claudin 1, 5 and 8, occludin and zonula occludens 1 mRNAs was detected after subacute stress in the jejunum. In contrast, colonic TEER was decreased only after combined stress, and the expression of tight junction molecules was unaltered. Increased mast cell density was observed in the chronic and combined stress condition in the colon only. In conclusion, our data show that chronic stress sensitizes the gastrointestinal tract to the effects of subacute stress on intestinal barrier function; different underlying cellular and molecular alterations are indicated in the small intestine versus the colon.

  9. Barriers and facilitators in the integration of oral health into primary care: a scoping review

    PubMed Central

    Harnagea, Hermina; Couturier, Yves; Shrivastava, Richa; Girard, Felix; Lamothe, Lise; Bedos, Christophe Pierre

    2017-01-01

    Objective This scoping study has been conducted to map the literature and provide a descriptive synthesis on the barriers and facilitators of the integration of oral health into primary care. Methods Grounded in the Rainbow conceptual model and using the Levac et al six-stage framework, we performed a systematic search of electronic databases, organisational websites and grey literature from 1978 to April 2016. All publications with a focus on the integration of oral health into primary care were included except commentaries and editorials. Thematic analyses were performed to synthesise the results. Results From a total of 1619 citations, 58 publications were included in the review. Barrier-related themes included: lack of political leadership and healthcare policies; implementation challenges; discipline-oriented education; lack of continuity of care and services and patients’ oral healthcare needs. The facilitators of integration were supportive policies and resources allocation, interdisciplinary education, collaborative practices between dental and other healthcare professionals, presence of local strategic leaders and geographical proximity. Discussion and public health implications This work has advanced the knowledge on the barriers and facilitators at each integration domain and level, which may be helpful if the healthcare organisations decide to integrate oral health and dental services into primary care. The scoping review findings could be useful for both dental and medical workforce and allied primary healthcare providers. They could also guide the development of healthcare policies that support collaborative practices and patient-centred care in the field of primary care. PMID:28951405

  10. Influencing physiotherapy student attitudes toward exercise for adolescents with Down syndrome.

    PubMed

    Shields, Nora; Bruder, Andrea; Taylor, Nicholas; Angelo, Tom

    2011-01-01

    Negative attitudes of physiotherapists may prevent them from implementing exercise as an intervention among people with disabilities. The aim of this study was to examine whether physiotherapy student attitudes towards the barriers to exercise for adolescents with Down syndrome changed as a result of participating in a 10-week exercise programme. Data were collected as part of a randomised controlled trial. Twenty physiotherapy students (2 men, 18 women; mean age 19.5±1.3 years) volunteered to act as mentors. Each mentor was matched with an adolescent with Down syndrome from the same metropolitan suburb, who had been randomly allocated to either the intervention or the control group. The 10 adolescents and students in the intervention group all completed a 10-week, twice a week progressive resistance exercise training programme. The 10 adolescents and students in the control group continued with their usual activities. The students completed the 18-item Exercise Barriers Scale at baseline and after 10 weeks. There was a positive change in attitudes, significant at the p <0.05 level, favouring the intervention group on 9 of the 18 items on the Exercise Barriers Scale. After engagement in a 10-week exercise programme with an adolescent with Down syndrome, physiotherapy students identified fewer barriers that would prevent adolescents with Down syndrome from exercising. Results indicate that contact with adolescents with Down syndrome during clinical placement can positively influence attitudes towards exercise for people with Down syndrome among physiotherapy students.

  11. Liposomal membrane disruption by means of miniaturized dielectric-barrier discharge in air: liposome characterization

    NASA Astrophysics Data System (ADS)

    Svarnas, P.; Asimakoulas, L.; Katsafadou, M.; Pachis, K.; Kostazos, N.; Antimisiaris, S. G.

    2017-08-01

    The increasing interest of the plasma community in the application of atmospheric-pressure cold plasmas to bio-specimen treatment has led to the creation of the emerging field of plasma biomedicine. Accordingly, plasma setups based on dielectric-barrier discharges have already been widely tested for the inactivation of various cells. Most of these systems refer to the plasma jet concept where noble gases penetrate atmospheric air and are subjected to the influence of high electric fields, thus forming guided streamers. Following the original works of our group where liposomal membranes were proposed as models for studying the interaction between plasma jets and cells, we present herein a study on liposomal membrane disruption by means of miniaturized dielectric-barrier discharge running in atmospheric air. Liposomal membranes of various lipid compositions, lamellarities, and sizes are treated at different times. It is shown that the dielectric-barrier discharge of low mean power leads to efficient liposomal membrane disruption. The latter is achieved in a controllable manner and depends on liposome properties. Additionally, it is clearly demonstrated that liposomal membrane disruption takes place even after plasma extinction, i.e. during post-treatment, resembling thus an ‘apoptosis’ effect, which is well known today mainly for cell membranes. Thus, the adoption of the present concept would be beneficial for tailoring studies on plasma-treated cell-mimics. Finally, the liposome treatment is discussed with respect to possible physicochemical mechanisms and potential discharge modification due to the various compositions of the liquid electrode.

  12. Adaptability in linkage of soil carbon nutrient cycles - the SEAM model

    NASA Astrophysics Data System (ADS)

    Wutzler, Thomas; Zaehle, Sönke; Schrumpf, Marion; Ahrens, Bernhard; Reichstein, Markus

    2017-04-01

    In order to understand the coupling of carbon (C) and nitrogen (N) cycles, it is necessary to understand C and N-use efficiencies of microbial soil organic matter (SOM) decomposition. While important controls of those efficiencies by microbial community adaptations have been shown at the scale of a soil pore, an abstract simplified representation of community adaptations is needed at ecosystem scale. Therefore we developed the soil enzyme allocation model (SEAM), which takes a holistic, partly optimality based approach to describe C and N dynamics at the spatial scale of an ecosystem and time-scales of years and longer. We explicitly modelled community adaptation strategies of resource allocation to extracellular enzymes and enzyme limitations on SOM decomposition. Using SEAM, we explored whether alternative strategy-hypotheses can have strong effects on SOM and inorganic N cycling. Results from prototypical simulations and a calibration to observations of an intensive pasture site showed that the so-called revenue enzyme allocation strategy was most viable. This strategy accounts for microbial adaptations to both, stoichiometry and amount of different SOM resources, and supported the largest microbial biomass under a wide range of conditions. Predictions of the SEAM model were qualitatively similar to models explicitly representing competing microbial groups. With adaptive enzyme allocation under conditions of high C/N ratio of litter inputs, N in formerly locked in slowly degrading SOM pools was made accessible, whereas with high N inputs, N was sequestered in SOM and protected from leaching. The finding that adaptation in enzyme allocation changes C and N-use efficiencies of SOM decomposition implies that concepts of C-nutrient cycle interactions should take account for the effects of such adaptations. This can be done using a holistic optimality approach.

  13. Visibility vs. biomass in flowers: exploring corolla allocation in Mediterranean entomophilous plants

    PubMed Central

    Herrera, Javier

    2009-01-01

    Background and Aims While pollinators may in general select for large, morphologically uniform floral phenotypes, drought stress has been proposed as a destabilizing force that may favour small flowers and/or promote floral variation within species. Methods The general validity of this concept was checked by surveying a taxonomically diverse array of 38 insect-pollinated Mediterranean species. The interplay between fresh biomass investment, linear size and percentage corolla allocation was studied. Allometric relationships between traits were investigated by reduced major-axis regression, and qualitative correlates of floral variation explored using general linear-model MANOVA. Key Results Across species, flowers were perfectly isometrical with regard to corolla allocation (i.e. larger flowers were just scaled-up versions of smaller ones and vice versa). In contrast, linear size and biomass varied allometrically (i.e. there were shape variations, in addition to variations in size). Most floral variables correlated positively and significantly across species, except corolla allocation, which was largely determined by family membership and floral symmetry. On average, species with bilateral flowers allocated more to the corolla than those with radial flowers. Plant life-form was immaterial to all of the studied traits. Flower linear size variation was in general low among conspecifics (coefficients of variation around 10 %), whereas biomass was in general less uniform (e.g. 200–400 mg in Cistus salvifolius). Significant among-population differences were detected for all major quantitative floral traits. Conclusions Flower miniaturization can allow an improved use of reproductive resources under prevailingly stressful conditions. The hypothesis that flower size reflects a compromise between pollinator attraction, water requirements and allometric constraints among floral parts is discussed. PMID:19258340

  14. Analysis of administrative barriers in the industry of the high-rise construction in Russian Federation

    NASA Astrophysics Data System (ADS)

    Zaychenko, Irina; Borremans, Alexandra; Gutman, Svetlana

    2018-03-01

    The article describes the concept and types of administrative barriers encountered in various areas of the enterprise. The particularities of the Russian high-rise construction industry are described and a comparative analysis of administrative barriers in this sector is performed. The main stages and administrative procedures when the developers implement investment and construction projects in the field of high-rise construction are determined. The regulatory and legal framework for the implementation of investment and project activities in the high-rise construction industry has been studied and conclusions have been drawn on its low level of precision in the issue of the formation of competitive and efficient high-rise construction markets. The average number of administrative procedures for the implementation of the investment and construction project in the field of high-rise construction is determined. The factors preventing the reduction of administrative barriers in the high-rise construction industry are revealed.

  15. Tunneling of heat: Beyond linear response regime

    NASA Astrophysics Data System (ADS)

    Walczak, Kamil; Saroka, David

    2018-02-01

    We examine nanoscale processes of heat (energy) transfer as carried by electrons tunneling via potential barriers and molecular interconnects between two heat reservoirs (thermal baths). For that purpose, we use Landauer-type formulas to calculate thermal conductance and quadratic correction to heat flux flowing via quantum systems. As an input, we implement analytical expressions for transmission functions related to simple potential barriers and atomic bridges. Our results are discussed with respect to energy of tunneling electrons, temperature, the presence of resonant states, and specific parameters characterizing potential barriers as well as heat carriers. The simplicity of semi-analytical models developed by us allows to fit experimental data and extract crucial information about the values of model parameters. Further investigations are expected for more realistic transmission functions, while time-dependent aspects of nanoscale heat transfer may be addressed by using the concept of wave packets scattered on potential barriers and point-like defects within regular (periodic) nanostructures.

  16. New research opportunities for roadside safety barriers improvement

    NASA Astrophysics Data System (ADS)

    Cantisani, Giuseppe; Di Mascio, Paola; Polidori, Carlo

    2017-09-01

    Among the major topics regarding the protection of roads, restraint systems still represent a big opportunity in order to increase safety performances. When accidents happen, in fact, the infrastructure can substantially contribute to the reduction of consequences if its marginal spaces are well designed and/or effective restraint systems are installed there. Nevertheless, basic concepts and technology of road safety barriers have not significantly changed for the last two decades. The paper proposes a new approach to the study aimed to define possible enhancements of restraint safety systems performances, by using new materials and defining innovative design principles. In particular, roadside systems can be developed with regard to vehicle-barrier interaction, vehicle-oriented design (included low-mass and extremely low-mass vehicles), traffic suitability, user protection, working width reduction. In addition, thanks to sensors embedded into the barriers, it is also expected to deal with new challenges related to the guidance of automatic vehicles and I2V communication.

  17. [Healthy eating according to teenagers: perceptions, barriers, and expected characteristics of teaching materials].

    PubMed

    Toral, Natacha; Conti, Maria Aparecida; Slater, Betzabeth

    2009-11-01

    The aim of this study was to evaluate perceptions, barriers, and characteristics of teaching materials to promote healthy eating, as described by teenagers. Four focus groups were conducted with 25 adolescents, including questions on: perceptions regarding diet and motivations to change; concepts of (and barriers to) healthy eating; and characteristics needed for teaching materials to promote healthy eating. The teens were often undecided when attempting to classify a diet as healthy. They generally reported feeling insecure about making dietary changes, but showed adequate notions of healthy eating. The main barriers involved personal and social characteristics: temptation, food flavors, parental influence, and lack of time and options for healthy snacks at school. According to these teenagers, educational materials for promotion of healthy eating should emphasize the immediate benefits and emphasize high-impact messages on the health risks of unhealthy diet.

  18. Impediments to media communication of social change in family planning and reproductive health: experiences from East Africa.

    PubMed

    Kagurusi, Patrick T

    2013-09-01

    The media has been employed to increase uptake of Family Planning through behaviour change communication (BCC). Understanding the barriers encountered in effectively undertaking this function would increase the strategy's effectiveness. Sixty journalists from East Africa participated in trainings to enhance their BCC skills for Family Planning in which a qualitative study was nested to identify barriers to effective Family Planning BCC in the region's media. The barriers were observed to be insufficient BCC skills, journalists' conflict of interest, interests of media houses, inaccessible sources of family planning information, editorial ideologies and absence of commercially beneficial demand. Coupled with the historical ideologies of the media in the region, the observed barriers have precipitated ineffective family planning BCC in the regions media. Effective BCC for family planning in the regions media requires capacity building among practitioners and alignment of the concept to the media's and consumers' aspirations.

  19. The rights and wrongs of blood-brain barrier permeability studies: a walk through 100 years of history

    PubMed Central

    Saunders, Norman R.; Dreifuss, Jean-Jacques; Dziegielewska, Katarzyna M.; Johansson, Pia A.; Habgood, Mark D.; Møllgård, Kjeld; Bauer, Hans-Christian

    2014-01-01

    Careful examination of relevant literature shows that many of the most cherished concepts of the blood-brain barrier are incorrect. These include an almost mythological belief in its immaturity that is unfortunately often equated with absence or at least leakiness in the embryo and fetus. The original concept of a blood-brain barrier is often attributed to Ehrlich; however, he did not accept that permeability of cerebral vessels was different from other organs. Goldmann is often credited with the first experiments showing dye (trypan blue) exclusion from the brain when injected systemically, but not when injected directly into it. Rarely cited are earlier experiments of Bouffard and of Franke who showed methylene blue and trypan red stained all tissues except the brain. The term “blood-brain barrier” “Blut-Hirnschranke” is often attributed to Lewandowsky, but it does not appear in his papers. The first person to use this term seems to be Stern in the early 1920s. Studies in embryos by Stern and colleagues, Weed and Wislocki showed results similar to those in adult animals. These were well-conducted experiments made a century ago, thus the persistence of a belief in barrier immaturity is puzzling. As discussed in this review, evidence for this belief, is of poor experimental quality, often misinterpreted and often not properly cited. The functional state of blood-brain barrier mechanisms in the fetus is an important biological phenomenon with implications for normal brain development. It is also important for clinicians to have proper evidence on which to advise pregnant women who may need to take medications for serious medical conditions. Beliefs in immaturity of the blood-brain barrier have held the field back for decades. Their history illustrates the importance of taking account of all the evidence and assessing its quality, rather than selecting papers that supports a preconceived notion or intuitive belief. This review attempts to right the wrongs. Based on careful translation of original papers, some published a century ago, as well as providing discussion of studies claiming to show barrier immaturity, we hope that readers will have evidence on which to base their own conclusions. PMID:25565938

  20. Ethics Education in Midwifery Education Programs in the United States.

    PubMed

    Megregian, Michele

    2016-09-01

    Familiarity with ethical concepts is a required competency for new graduates and a component of accreditation for midwifery education programs in the United States. While midwifery educators have acknowledged the importance of ethics education in midwifery programs, little is known about current methods, format, or evaluation of ethics education. A Web-based survey was developed for program directors of accredited midwifery education programs in the United States. Clock hours, formats, venues, content topics, barriers, and evaluation methods were evaluated by descriptive analysis. Fifty-one percent of programs completed the online survey (25/49). Of these, only 7 (28%) offer ethics as a stand-alone class, although all responding programs integrate some ethics education into other core classes. Programs show variation in format, venue, resources, and clock hours dedicated to ethics education. The most frequent barrier to ethics education is an already crowded curriculum (60%), although 32% of programs denied any barriers at all. The majority of programs include the ethical concepts of informed consent, shared decision making, and effective communication in curriculum content. This survey found that there is considerable variation in ethics education in terms of content, format, and evaluation among accredited midwifery education programs in the United States. Midwifery educators have an opportunity to explore the ethical dilemmas unique to maternity care from a midwifery perspective. There is also the opportunity to create a comprehensive and dynamic midwifery ethics curriculum, which incorporates both stand-alone ethics courses and ethics concepts that are woven throughout the core midwifery curriculum. © 2016 by the American College of Nurse-Midwives.

  1. Challenges to Providing Fetal Anomaly Testing in a Cross-Cultural Environment: Experiences of Practitioners Caring for Aboriginal Women.

    PubMed

    Rumbold, Alice R; Wild, Kayli J; Maypilama, Elaine Lawurrpa; Kildea, Sue V; Barclay, Lesley; Wallace, Euan M; Boyle, Jacqueline A

    2015-12-01

    Across Australia there are substantial disparities in uptake of antenatal testing for fetal anomalies, with very low uptake observed among Aboriginal women. The reasons behind these disparities are unclear, although poorer access to testing has been reported in some communities. We interviewed health care practitioners to explore the perceived barriers to providing fetal anomaly screening to Aboriginal women. In 2009 and 2010, in-depth interviews were undertaken with 59 practitioners in five urban and remote sites across the Northern Territory (NT) of Australia. Data were analyzed thematically. Maximum variation sampling, independent review of findings by multiple analysts, and participant feedback were undertaken to strengthen the validity of findings. Participants included midwives (47%), Aboriginal health practitioners (AHP) (32%), general practitioners (12%), and obstetricians (9%); almost all (95%) were female. Participants consistently reported difficulties counseling women. Explaining the concept of "risk" (of abnormalities and the screening test result) was identified as particularly challenging, because of a perceived lack of an equivalent concept in Aboriginal languages. While AHPs could assist with overcoming language barriers, they are underutilized. Participants also identified impediments to organizing testing including difficulties establishing gestational age, late presentation for care, and a lack of standardized information and training. The availability of fetal anomaly testing is challenged by communication difficulties, including a focus on culturally specific biomedical concepts, and organizational barriers to arranging testing. Developing educational activities that address the technical aspects of screening and communication skills will assist in improving access. These activities must include AHPs. © 2015 Wiley Periodicals, Inc.

  2. Implementing a 6-day physiotherapy service in rehabilitation: exploring staff perceptions.

    PubMed

    Caruana, Erin L; Kuys, Suzanne S; Clarke, Jane; Brauer, Sandra G

    2017-11-20

    Objective Australian weekend rehabilitation therapy provision is increasing. Staff engagement optimises service delivery. The present mixed-methods process evaluation explored staff perceptions regarding implementation of a 6-day physiotherapy service in a private rehabilitation unit. Methods All multidisciplinary staff working in the rehabilitation unit were surveyed regarding barriers, facilitators and perceptions of the effect of a 6-day physiotherapy service on length of stay (LOS) and patient goal attainment at three time points: before and after implementation, as well as after modification of a 6-day physiotherapy service. Descriptive statistics and thematic analysis was used to analyse the data. Results Fifty-one staff (50%) responded. Before implementation, all staff identified barriers, the most common being staffing (62%) and patient selection (29%). After implementation, only 30% of staff identified barriers, which differed to those identified before implementation, and included staff rostering and experience (20%), timing of therapy (10%) and increasing the allocation of patients (5%). Over time, staff perceptions changed from being unsure to being positive about the effect of the 6-day service on LOS and patient goal attainment. Conclusion Staff perceived a large number of barriers before implementation of a 6-day rehabilitation service, but these did not eventuate following implementation. Staff perceived improved LOS and patient goal attainment after implementation of a 6-day rehabilitation service incorporating staff feedback. What is known about this topic? Rehabilitation weekend services improve patient quality of life and functional independence while reducing LOS. What does this study add? Staff feedback during implementation and modification of new services is important to address potential barriers and ensure staff satisfaction and support. What are the implications for practitioners? Staff engagement and open communication are important to successfully implement a new service in rehabilitation.

  3. An exploratory randomised controlled trial of a premises-level intervention to reduce alcohol-related harm including violence in the United Kingdom

    PubMed Central

    2012-01-01

    Background To assess the feasibility of a randomised controlled trial of a licensed premises intervention to reduce severe intoxication and disorder; to establish effect sizes and identify appropriate approaches to the development and maintenance of a rigorous research design and intervention implementation. Methods An exploratory two-armed parallel randomised controlled trial with a nested process evaluation. An audit of risk factors and a tailored action plan for high risk premises, with three month follow up audit and feedback. Thirty-two premises that had experienced at least one assault in the year prior to the intervention were recruited, match paired and randomly allocated to control or intervention group. Police violence data and data from a street survey of study premises’ customers, including measures of breath alcohol concentration and surveyor rated customer intoxication, were used to assess effect sizes for a future definitive trial. A nested process evaluation explored implementation barriers and the fidelity of the intervention with key stakeholders and senior staff in intervention premises using semi-structured interviews. Results The process evaluation indicated implementation barriers and low fidelity, with a reluctance to implement the intervention and to submit to a formal risk audit. Power calculations suggest the intervention effect on violence and subjective intoxication would be raised to significance with a study size of 517 premises. Conclusions It is methodologically feasible to conduct randomised controlled trials where licensed premises are the unit of allocation. However, lack of enthusiasm in senior premises staff indicates the need for intervention enforcement, rather than voluntary agreements, and on-going strategies to promote sustainability. Trial registration UKCRN 7090; ISRCTN: 80875696 PMID:22676069

  4. Companion of choice at birth: factors affecting implementation.

    PubMed

    Kabakian-Khasholian, Tamar; Portela, Anayda

    2017-08-31

    Two recent recommendations made by the World Health Organization confirm the benefits of companion of choice at birth on labour outcomes; however institutional practices and policies do not always support its implementation in different settings around the world. We conducted a review to determine factors that affect implementation of this intervention considering the perspectives and experiences of different stakeholders and other institutional, systemic barriers and facilitators. Forty one published studies were included in this review. Thirty one publications were identified from a 2013 Cochrane review on the effectiveness of companion of choice at birth. We also reviewed 10 qualitative studies conducted alongside the trials or other interventions on labour and birth companionship identified through electronic searches. The SURE (Supporting the Use of Research Evidence) framework was used to guide the thematic analysis of implementation factors. Women and their families expressed appreciation for the continuous presence of a person to provide support during childbirth. Health care providers were concerned about the role of the companion and possible interference with activities in the labour ward. Allocation of resources, organization of care, facility-related constraints and cultural inclinations were identified as implementation barriers. Prior to introducing companion of choice at birth, understanding providers' attitudes and sensitizing them to the evidence is necessary. The commitment of the management of health care facilities is also required to change policies, including allocation of appropriate physical space that respects women's privacy. Implementation research to develop models for different contexts which could be scaled up would be useful, including documentation of factors that affected implementation and how they were addressed. Future research should also focus on documenting the costs related to implementation, and on measuring the impact of companion of choice at birth on care-seeking behavior for subsequent births.

  5. General form of a cooperative gradual maximal covering location problem

    NASA Astrophysics Data System (ADS)

    Bagherinejad, Jafar; Bashiri, Mahdi; Nikzad, Hamideh

    2018-07-01

    Cooperative and gradual covering are two new methods for developing covering location models. In this paper, a cooperative maximal covering location-allocation model is developed (CMCLAP). In addition, both cooperative and gradual covering concepts are applied to the maximal covering location simultaneously (CGMCLP). Then, we develop an integrated form of a cooperative gradual maximal covering location problem, which is called a general CGMCLP. By setting the model parameters, the proposed general model can easily be transformed into other existing models, facilitating general comparisons. The proposed models are developed without allocation for physical signals and with allocation for non-physical signals in discrete location space. Comparison of the previously introduced gradual maximal covering location problem (GMCLP) and cooperative maximal covering location problem (CMCLP) models with our proposed CGMCLP model in similar data sets shows that the proposed model can cover more demands and acts more efficiently. Sensitivity analyses are performed to show the effect of related parameters and the model's validity. Simulated annealing (SA) and a tabu search (TS) are proposed as solution algorithms for the developed models for large-sized instances. The results show that the proposed algorithms are efficient solution approaches, considering solution quality and running time.

  6. Flexible operation strategy for environment control system in abnormal supply power condition

    NASA Astrophysics Data System (ADS)

    Liping, Pang; Guoxiang, Li; Hongquan, Qu; Yufeng, Fang

    2017-04-01

    This paper establishes an optimization method that can be applied to the flexible operation of the environment control system in an abnormal supply power condition. A proposed conception of lifespan is used to evaluate the depletion time of the non-regenerative substance. The optimization objective function is to maximize the lifespans. The optimization variables are the allocated powers of subsystems. The improved Non-dominated Sorting Genetic Algorithm is adopted to obtain the pareto optimization frontier with the constraints of the cabin environmental parameters and the adjustable operating parameters of the subsystems. Based on the same importance of objective functions, the preferred power allocation of subsystems can be optimized. Then the corresponding running parameters of subsystems can be determined to ensure the maximum lifespans. A long-duration space station with three astronauts is used to show the implementation of the proposed optimization method. Three different CO2 partial pressure levels are taken into consideration in this study. The optimization results show that the proposed optimization method can obtain the preferred power allocation for the subsystems when the supply power is at a less-than-nominal value. The method can be applied to the autonomous control for the emergency response of the environment control system.

  7. Modelling the effect of environmental factors on resource allocation in mixed plants systems

    NASA Astrophysics Data System (ADS)

    Gayler, Sebastian; Priesack, Eckart

    2010-05-01

    In most cases, growth of plants is determined by competition against neighbours for the local resources light, water and nutrients and by defending against herbivores and pathogens. Consequently, it is important for a plant to grow fast without neglecting defence. However, plant internal substrates and energy required to support maintenance, growth and defence are limited and the total demand for these processes cannot be met in most cases. Therefore, allocation of carbohydrates to growth related primary metabolism or to defence related secondary metabolism can be seen as a trade-off between the demand of plants for being competitive against neighbours and for being more resistant against pathogens. A modelling approach is presented which can be used to simulate competition for light, water and nutrients between plant individuals in mixed canopies. The balance of resource allocation between growth processes and synthesis of secondary compounds is modelled by a concept originating from different plant defence hypothesis. The model is used to analyse the impact of environmental factors such as soil water and nitrogen availability, planting density and atmospheric concentration of CO2 on growth of plant individuals within mixed canopies and variations in concentration of carbon-based secondary metabolites in plant tissues.

  8. Enhancing ecosystem restoration efficiency through spatial and temporal coordination.

    PubMed

    Neeson, Thomas M; Ferris, Michael C; Diebel, Matthew W; Doran, Patrick J; O'Hanley, Jesse R; McIntyre, Peter B

    2015-05-12

    In many large ecosystems, conservation projects are selected by a diverse set of actors operating independently at spatial scales ranging from local to international. Although small-scale decision making can leverage local expert knowledge, it also may be an inefficient means of achieving large-scale objectives if piecemeal efforts are poorly coordinated. Here, we assess the value of coordinating efforts in both space and time to maximize the restoration of aquatic ecosystem connectivity. Habitat fragmentation is a leading driver of declining biodiversity and ecosystem services in rivers worldwide, and we simultaneously evaluate optimal barrier removal strategies for 661 tributary rivers of the Laurentian Great Lakes, which are fragmented by at least 6,692 dams and 232,068 road crossings. We find that coordinating barrier removals across the entire basin is nine times more efficient at reconnecting fish to headwater breeding grounds than optimizing independently for each watershed. Similarly, a one-time pulse of restoration investment is up to 10 times more efficient than annual allocations totaling the same amount. Despite widespread emphasis on dams as key barriers in river networks, improving road culvert passability is also essential for efficiently restoring connectivity to the Great Lakes. Our results highlight the dramatic economic and ecological advantages of coordinating efforts in both space and time during restoration of large ecosystems.

  9. Enhancing ecosystem restoration efficiency through spatial and temporal coordination

    PubMed Central

    Neeson, Thomas M.; Ferris, Michael C.; Diebel, Matthew W.; Doran, Patrick J.; O’Hanley, Jesse R.; McIntyre, Peter B.

    2015-01-01

    In many large ecosystems, conservation projects are selected by a diverse set of actors operating independently at spatial scales ranging from local to international. Although small-scale decision making can leverage local expert knowledge, it also may be an inefficient means of achieving large-scale objectives if piecemeal efforts are poorly coordinated. Here, we assess the value of coordinating efforts in both space and time to maximize the restoration of aquatic ecosystem connectivity. Habitat fragmentation is a leading driver of declining biodiversity and ecosystem services in rivers worldwide, and we simultaneously evaluate optimal barrier removal strategies for 661 tributary rivers of the Laurentian Great Lakes, which are fragmented by at least 6,692 dams and 232,068 road crossings. We find that coordinating barrier removals across the entire basin is nine times more efficient at reconnecting fish to headwater breeding grounds than optimizing independently for each watershed. Similarly, a one-time pulse of restoration investment is up to 10 times more efficient than annual allocations totaling the same amount. Despite widespread emphasis on dams as key barriers in river networks, improving road culvert passability is also essential for efficiently restoring connectivity to the Great Lakes. Our results highlight the dramatic economic and ecological advantages of coordinating efforts in both space and time during restoration of large ecosystems. PMID:25918378

  10. Selection of a method to rate the strength of scientific evidence for AORN recommendations.

    PubMed

    Steelman, Victoria M; Pape, Theresa; King, Cecil A; Graling, Paula; Gaberson, Kathleen B

    2011-04-01

    The use of scientific evidence to support national recommendations about clinical decisions has become an expectation of multidisciplinary health care organizations. The objectives of this project were to identify the most applicable evidence-rating method for perioperative nursing practice, evaluate the reliability of this method for perioperative nursing recommendations, and identify barriers and facilitators to adoption of this method for AORN recommendations. A panel of perioperative nurse experts evaluated 46 evidence-rating systems for quality, quantity, and consistency. We rated the methods that fully covered all three domains on five aspects of applicability to perioperative nursing practice recommendations. The Oncology Nursing Society's method was rated highest for all five aspects of applicability, and interrater reliability of this method for perioperative recommendations was 100%. Potential barriers to implementation of the rating method include knowledge deficit, staff resources, resistance to change, and fear of showing that lower levels of evidence support some recommendations. Facilitators included education, resource allocation, and starting small. Barriers and facilitators will be considered by the implementation team that will develop a plan to achieve integration of evidence rating into AORN documents. The AORN Board of Directors approved adoption of this method in June 2010. Copyright © 2011 AORN, Inc. Published by Elsevier Inc. All rights reserved.

  11. Investigations of plastic composite materials for highway safety structures

    DOT National Transportation Integrated Search

    1998-08-01

    This report presents a basic overview and assessment of different concepts and technologies of using polymer composites in structures generally used for highway safety. The structural systems included a highway barrier guardrail with its posts and bl...

  12. Space station Simulation Computer System (SCS) study for NASA/MSFC. Volume 2: Concept document

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The Simulation Computer System (SCS) concept document describes and establishes requirements for the functional performance of the SCS system, including interface, logistic, and qualification requirements. The SCS is the computational communications and display segment of the Marshall Space Flight Center (MSFC) Payload Training Complex (PTC). The PTC is the MSFC facility that will train onboard and ground operations personnel to operate the payloads and experiments on board the international Space Station Freedom. The requirements to be satisfied by the system implementation are identified here. The SCS concept document defines the requirements to be satisfied through the implementation of the system capability. The information provides the operational basis for defining the requirements to be allocated to the system components and enables the system organization to assess whether or not the completed system complies with the requirements of the system.

  13. New level of vehicle comfort and vehicle stability via utilisation of the suspensions anti-dive and anti-squat geometry

    NASA Astrophysics Data System (ADS)

    Lindvai-Soos, Daniel; Horn, Martin

    2018-07-01

    In this article a novel vehicle dynamics control concept is designed for a vehicle equipped with wheel individual electric traction machines, electronically controlled brakes and semi-active suspensions. The suspension's cross-couplings between traction forces and vertical forces via anti-dive and anti-squat geometry is utilised in the control concept to improve driving comfort and driving stability. The control concept is divided into one main and two cascaded branches. The main controller consists of a multivariable vehicle dynamics controller and a control allocation scheme to improve the vehicle's driving comfort. The cascaded feedback loops maintain the vehicle's stability according to wheel slip and vehicle sideslip. The performance of the combined vehicle dynamics controller is compared to a standard approach in simulation. It can be stated that the controller piloting semi-active suspensions together with brake and traction devices enables a superior performance regarding comfort and stability.

  14. Final Report for the Advanced Concept Studies for Supersonic Commercial Transports Entering Service in the 2030 to 2035 Period, N+3 Supersonic Program

    NASA Technical Reports Server (NTRS)

    Morgenstern, John; Norstrud, Nicole; Stelmack, Marc; Skoch, Craig

    2010-01-01

    The N+3 Final Report documents the work and progress made by Lockheed Martin Aeronautics in response to the NASA sponsored program "N+3 NRA Advanced Concept Studies for Supersonic Commercial Transports Entering Service in the 2030 to 2035 Period." The key technical objective of this effort was to generate promising supersonic concepts for the 2030 to 2035 timeframe and to develop plans for maturing the technologies required to make those concepts a reality. The N+3 program is aligned with NASA's Supersonic Project and is focused on providing alternative system-level solutions capable of overcoming the efficiency, environmental, and performance barriers to practical supersonic flight

  15. A cooperative game-theoretic framework for negotiating marine spatial allocation agreements among heterogeneous players.

    PubMed

    Kyriazi, Zacharoula; Lejano, Raul; Maes, Frank; Degraer, Steven

    2017-02-01

    Marine spatial allocation has become, in recent decades, a political flashpoint, fuelled by political power struggles, as well as the continuously increasing demand for marine space by both traditional and emerging marine uses. To effectively address this issue, we develop a decision-making procedure, that facilitates the distribution of disputed areas of specific size among heterogeneous players in a transparent and ethical way, while considering coalitional formations through coexistence. To do this, we model players' alternative strategies and payoffs within a cooperative game-theoretic framework. Depending on whether transferable utility (TU) or non-transferable utility (NTU) is the more appropriate assumption, we illustrate the use of the TU Shapley value and the Lejano's fixed point NTU Shapley value to solve for the ideal allocations. The applicability and effectiveness of the process has been tested in a case study area, the Dogger Bank Special Area of Conservation in the North Sea, which involves three totally or partially conflicting activities, i.e. fishing, nature conservation and wind farm development. The findings demonstrate that the process is capable of providing a unique, fair and equitable division of space Finally, among the two solution concepts proposed the fixed point NTU Shapley value manages to better address the heterogeneity of the players and thus to provide a more socially acceptable allocation that favours the weaker player, while demonstrating the importance of the monetary valuation attributed by each use to the area. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. On the asteroid hazard

    NASA Astrophysics Data System (ADS)

    Eneev, T. M.; Akhmetshin, R. Z.; Efimov, G. B.

    2012-04-01

    The concept of "space patrol" is considered, aimed at discovering and cataloging the majority of celestial bodies that constitute a menace for the Earth [1, 2]. The scheme of "optical barrier" formed by telescopes of the space patrol is analyzed, requirements to the observation system are formulated, and some schemes of sighting the optical barrier region are suggested (for reliable detection of the celestial bodies approaching the Earth and for determination of their orbits). A comparison is made of capabilities of electro-jet engines and traditional chemical engines for arrangement of patrol spacecraft constellation in the Earth's orbit.

  17. Understanding the investigators: a qualitative study investigating the barriers and enablers to the implementation of local investigator-initiated clinical trials in Ethiopia

    PubMed Central

    Franzen, Samuel R P; Chandler, Clare; Enquselassie, Fikre; Siribaddana, Sisira; Atashili, Julius; Angus, Brian; Lang, Trudie

    2013-01-01

    Objectives Clinical trials provide ‘gold standard’ evidence for policy, but insufficient locally relevant trials are conducted in low-income and middle-income countries. Local investigator-initiated trials could generate highly relevant data for national governments, but information is lacking on how to facilitate them. We aimed to identify barriers and enablers to investigator-initiated trials in Ethiopia to inform and direct capacity strengthening initiatives. Design Exploratory, qualitative study comprising of in-depth interviews (n=7) and focus group discussions (n=3). Setting Fieldwork took place in Ethiopia during March 2011. Participants Local health researchers with previous experiences of clinical trials or stakeholders with an interest in trials were recruited through snowball sampling (n=20). Outcome measures Detailed discussion notes were analysed using thematic coding analysis and key themes were identified. Results All participants perceived investigator-initiated trials as important for generating local evidence. System and organisational barriers included: limited funding allocation, weak regulatory and administrative systems, few learning opportunities, limited human and material capacity and poor incentives for conducting research. Operational hurdles were symptomatic of these barriers. Lack of awareness, confidence and motivation to undertake trials were important individual barriers. Training, knowledge sharing and experience exchange were key enablers to trial conduct and collaboration was unanimously regarded as important for improving capacity. Conclusions Barriers to trial conduct were found at individual, operational, organisational and system levels. These findings indicate that to increase locally led trial conduct in Ethiopia, system wide changes are needed to create a more receptive and enabling research environment. Crucially, the creation of research networks between potential trial groups could provide much needed practical collaborative support through sharing of financial and project management burdens, knowledge and resources. These findings could have important implications for capacity-strengthening initiatives but further research is needed before the results can be generalised more widely. PMID:24285629

  18. Concepts, The Journal of Defense Systems Acquisition Management, Autumn 1981, Volume 4, Number 4.

    DTIC Science & Technology

    1981-01-01

    Reduction in corporate tax rates could provide the needed in- centive for defense contractors to increase their capital investments. The time to take...34penalty for non-fulfillment" is found to be useful in incorpo- rating value judgments into the allocation of resources. Penalty for non-fulfill- ment is...Production Rate Changes: I. Redistributing Fixed Overhead Costs, Cm dr. Steve 1. Balut, USN .......................................... 63 II. Effect of

  19. Virtual volatility

    NASA Astrophysics Data System (ADS)

    Silva, A. Christian; Prange, Richard E.

    2007-03-01

    We introduce the concept of virtual volatility. This simple but new measure shows how to quantify the uncertainty in the forecast of the drift component of a random walk. The virtual volatility also is a useful tool in understanding the stochastic process for a given portfolio. In particular, and as an example, we were able to identify mean reversion effect in our portfolio. Finally, we briefly discuss the potential practical effect of the virtual volatility on an investor asset allocation strategy.

  20. Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project

    NASA Technical Reports Server (NTRS)

    Griner, James H.

    2013-01-01

    NASA's UAS Integration in the NAS project, has partnered with Rockwell Collins to develop a concept Control and Non-Payload Communication system prototype radio, operating on recently allocated UAS frequency spectrum bands. The prototype radio will be used to validate initial proposed performance requirements for UAS control communications. This presentation will give an overview of the current status of the design, development, and flight test planning for this prototype radio.

  1. Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project - Gen-4 and Gen-5 Radio Plans

    NASA Technical Reports Server (NTRS)

    Griner, James H.

    2014-01-01

    NASA's UAS Integration in the NAS project, has partnered with Rockwell Collins to develop a concept Control and Non-Payload Communication (CNPC) system prototype radio, operating on recently allocated UAS frequency spectrum bands. This prototype radio is being used to validate initial proposed performance requirements for UAS control communications. This presentation will give an overview of the current plans for the prototype radio development.

  2. Transforming the Air Traffic Management System -- Why Is It So Hard?

    DTIC Science & Technology

    2012-11-08

    Aircraft Systems Integration The Equity Concept Chocolate Cake Problem: How can I distribute this cake equitably among each of the students sitting...net-centric system. – Timely, common information will be available to all (humans and machines ) to help them make their decisions. – While any change...prioritization done when scarce resources must be allocated? (Remember how hard it was to distribute the chocolate cake!) ADS-B In-Trail Procedures

  3. FD/DAMA Scheme For Mobile/Satellite Communications

    NASA Technical Reports Server (NTRS)

    Yan, Tsun-Yee; Wang, Charles C.; Cheng, Unjeng; Rafferty, William; Dessouky, Khaled I.

    1992-01-01

    Integrated-Adaptive Mobile Access Protocol (I-AMAP) proposed to allocate communication channels to subscribers in first-generation MSAT-X mobile/satellite communication network. Based on concept of frequency-division/demand-assigned multiple access (FD/DAMA) where partition of available spectrum adapted to subscribers' demands for service. Requests processed, and competing requests resolved according to channel-access protocol, or free-access tree algorithm described in "Connection Protocol for Mobile/Satellite Communications" (NPO-17735). Assigned spectrum utilized efficiently.

  4. Simulation of flow in the Edwards Aquifer, San Antonio region, Texas, and refinement of storage and flow concepts

    USGS Publications Warehouse

    Maclay, Robert W.; Land, Larry F.

    1988-01-01

    The Edwards aquifer is a complexly faulted, carbonate aquifer lying within the Balcones fault zone of south-central Texas. The aquifer consists of thin- to massive-bedded limestone and dolomite, most of which is in the form of mudstones and wackestones. Well-developed secondary porosity has formed in association with former erosional surfaces within the carbonate rocks, within dolomitized-burrowed tidal and evaporitic deposits, and along inclined fractures to produce an aquifer with transmissivities greater than 100 ft2/s. The aquifer is recharged mainly by streamflow losses in the outcrop area of the Edwards aquifer and is discharged by major springs located at considerable distances, as much as 150 mi, from the areas of recharge and by wells. Ground-water flow within the Edwards aquifer of the San Antonio region was simulated to investigate concepts relating to the storage and flow characteristics. The concepts of major interest were the effects of barrier faults on flow direction, water levels, springflow, and storage within the aquifer. A general-purpose, finite-difference model, modified to provide the capability of representing barrier faults, was used to simulate ground-water flow and storage in the aquifer. The approach in model development was to conduct a series of simulations beginning with a simple representation of the aquifer framework and then proceeding to subsequent representations of increasing complexity. The simulations investigated the effects of complex geologic structures and of significant changes in transmissivity, anisotropy, and storage coefficient. Initial values of transmissivity, anisotropy, and storage coefficient were estimated based on concepts developed in previous studies. Results of the simulations confirmed the original estimates of transmissivity values (greater than 100 square feet/s) in the confined zone of the aquifer between San Antonio and Comal Springs. A storage coefficient of 0.05 in the unconfined zone of the aquifer produced the best simulation of water levels and springflow. A major interpretation resulting from the simulations is that two essentially independent areas of regional flow were identified in the west and central part of the study area. Flows from the two areas converge at Comal Springs. The directions of computed flux vectors reflected the presence of major barrier faults, which locally deflect patterns of ground-water movement. The most noticeable deflection is the convergence of flow through a geologic structural opening, the Knippa gap, in eastern Uvalde County. A second significant interpretation is that ground-water flow in northeastern Bexar, Comal, and Hays Counties is diverted by barrier faults toward San Marcos Springs, a regional discharge point. Simulations showed that several barrier faults in the northwestern part of the San Antonio area had a significant effect on storage, water levels, and springflow within the Edwards aquifer.

  5. A Nano-Selenium Reactive Barrier Approach for Managing Mercury over the Life-Cycle of Compact Fluorescent Lamps

    PubMed Central

    Lee, Brian; Sarin, Love; Johnson, Natalie C.; Hurt, Robert H.

    2013-01-01

    Compact fluorescent lamps contain small quantities of mercury, whose release can lead to human exposures of potential concern in special cases involving multiple lamps, confined spaces, or young children. The exposure scenarios typically involve solid lamp debris that slowly releases elemental mercury vapor to indoor spaces. Here we propose and demonstrate a reactive barrier approach for the suppression of that mercury release, and demonstrate the concept using uncoated amorphous nano-selenium as the reactive component. Multi-layer structures containing an impregnated reactive layer and a mercury vapor barrier are fabricated, characterized, and evaluated in three exposure prevention scenarios: carpeted break sites, disposal/recycling bags, and boxes as used for retail sales, shipping and collection. The reactive barriers achieve significant suppression of mercury release to indoor spaces in each of the three scenarios. The nano-selenium barriers also exhibit a unique indicator function that can reveal the location of Hg-contamination by local reaction-induced change in optical properties. The article also presents results on equilibrium Hg vapor pressure above lamp debris, mathematical modeling of reaction and transport processes within reactive barriers, and landfill stability of nano-selenium and its reaction products. PMID:19731697

  6. A nano-selenium reactive barrier approach for managing mercury over the life-cycle of compact fluorescent lamps.

    PubMed

    Lee, Brian; Sarin, Love; Johnson, Natalie C; Hurt, Robert H

    2009-08-01

    Compact fluorescent lamps contain small quantities of mercury, release of which can lead to human exposures of potential concern in special cases involving multiple lamps, confined spaces, or young children. The exposure scenarios typically involve solid lamp debris that slowly releases elemental mercury vapor to indoor spaces. Here we propose and demonstrate a reactive barrier approach for the suppression of that mercury release, and demonstrate the concept using uncoated amorphous nanoselenium as the reactive component. Multilayer structures containing an impregnated reactive layer and a mercury vapor barrier are fabricated, characterized, and evaluated in three exposure prevention scenarios: carpeted break sites, disposal/recycling bags, and boxes as used for retail sales, shipping, and collection. The reactive barriers achieve significant suppression of mercury release to indoor spaces in each of thethree scenarios. The nanoselenium barriers also exhibit a unique indicator function that can reveal the location of Hg contamination by local reaction-induced change in optical properties. The article also presents results on equilibrium Hg vapor pressure above lamp debris, mathematical modeling of reaction and transport processes within reactive barriers, and landfill stability of nanoselenium and its reaction products.

  7. Barriers and Strategies for Recruitment of Racial and Ethnic Minorities: Perspectives from Neurological Clinical Research Coordinators.

    PubMed

    Haley, Sean J; Southwick, Lauren E; Parikh, Nina S; Rivera, Jazmin; Farrar-Edwards, Dorothy; Boden-Albala, Bernadette

    2017-12-01

    Randomized controlled trials (RCTs) are the gold standard within evidence-based research. Low participant accrual rates, especially of underrepresented groups (e.g., racial-ethnic minorities), may jeopardize clinical studies' viability and strength of findings. Research has begun to unweave clinical trial mechanics, including the roles of clinical research coordinators, to improve trial participation rates. Two semi-structured focus groups were conducted with a purposive sample of 29 clinical research coordinators (CRCs) at consecutive international stroke conferences in 2013 and 2014 to gain in-depth understanding of coordinator-level barriers to racial-ethnic minority recruitment and retention into neurological trials. Coded transcripts were used to create themes to define concepts, identify associations, summarize findings, and posit explanations. Barriers related to translation, literacy, family composition, and severity of medical diagnosis were identified. Potential strategies included a focus on developing personal relationships with patients, community and patient education, centralized clinical trial administrative systems, and competency focused training and education for CRCs. Patient level barriers to clinical trial recruitment are well documented. Less is known about barriers facing CRCs. Further identification of how and when barriers manifest and the effectiveness of strategies to improve CRCs recruitment efforts is warranted.

  8. Integrated approach to modeling long-term durability of concrete engineered barriers in LLRW disposal facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, J.H.; Roy, D.M.; Mann, B.

    1995-12-31

    This paper describes an integrated approach to developing a predictive computer model for long-term performance of concrete engineered barriers utilized in LLRW and ILRW disposal facilities. The model development concept consists of three major modeling schemes: hydration modeling of the binder phase, pore solution speciation, and transport modeling in the concrete barrier and service environment. Although still in its inception, the model development approach demonstrated that the chemical and physical properties of complex cementitious materials and their interactions with service environments can be described quantitatively. Applying the integrated model development approach to modeling alkali (Na and K) leaching from amore » concrete pad barrier in an above-grade tumulus disposal unit, it is predicted that, in a near-surface land disposal facility where water infiltration through the facility is normally minimal, the alkalis control the pore solution pH of the concrete barriers for much longer than most previous concrete barrier degradation studies assumed. The results also imply that a highly alkaline condition created by the alkali leaching will result in alteration of the soil mineralogy in the vicinity of the disposal facility.« less

  9. International Terminology.

    ERIC Educational Resources Information Center

    Nedobity, W.

    Uniformity, and thus internationalization, of concepts and terms in special-purpose languages is desirable for reducing language barriers in the transfer of scientific and technological information. This is important for both industrialized nations and countries with small economies. Training of skilled personnel in developing nations has always…

  10. CONTROL OF ZOONOTIC DISEASES IN DRINKING WATER

    EPA Science Inventory

    For over a century, the process of providing hygienically safe drinking water has focused on utilizing treatment processes to provide barriers to the passage of infectious disease-causing organisms to humans. This concept is often considered the cornerstone of sanitary engineerin...

  11. The Anatomy of a Constitutional Tort.

    ERIC Educational Resources Information Center

    Horner, Jeffrey J.

    1988-01-01

    Given state law barriers to recovery for the negligence of public officials, redress is often sought in federal courts. Discusses the concept of "constitutional tort" and analyzes the various components and the elements that must be satisfied before recovery is allowed. (MLF)

  12. Outer brain barriers in rat and human development

    PubMed Central

    Brøchner, Christian B.; Holst, Camilla B.; Møllgård, Kjeld

    2015-01-01

    Complex barriers at the brain's surface, particularly in development, are poorly defined. In the adult, arachnoid blood-cerebrospinal fluid (CSF) barrier separates the fenestrated dural vessels from the CSF by means of a cell layer joined by tight junctions. Outer CSF-brain barrier provides diffusion restriction between brain and subarachnoid CSF through an initial radial glial end feet layer covered with a pial surface layer. To further characterize these interfaces we examined embryonic rat brains from E10 to P0 and forebrains from human embryos and fetuses (6–21st weeks post-conception) and adults using immunohistochemistry and confocal microscopy. Antibodies against claudin-11, BLBP, collagen 1, SSEA-4, MAP2, YKL-40, and its receptor IL-13Rα2 and EAAT1 were used to describe morphological characteristics and functional aspects of the outer brain barriers. Claudin-11 was a reliable marker of the arachnoid blood-CSF barrier. Collagen 1 delineated the subarachnoid space and stained pial surface layer. BLBP defined radial glial end feet layer and SSEA-4 and YKL-40 were present in both leptomeningeal cells and end feet layer, which transformed into glial limitans. IL-13Rα2 and EAAT1 were present in the end feet layer illustrating transporter/receptor presence in the outer CSF-brain barrier. MAP2 immunostaining in adult brain outlined the lower border of glia limitans; remnants of end feet were YKL-40 positive in some areas. We propose that outer brain barriers are composed of at least 3 interfaces: blood-CSF barrier across arachnoid barrier cell layer, blood-CSF barrier across pial microvessels, and outer CSF-brain barrier comprising glial end feet layer/pial surface layer. PMID:25852456

  13. Outer brain barriers in rat and human development.

    PubMed

    Brøchner, Christian B; Holst, Camilla B; Møllgård, Kjeld

    2015-01-01

    Complex barriers at the brain's surface, particularly in development, are poorly defined. In the adult, arachnoid blood-cerebrospinal fluid (CSF) barrier separates the fenestrated dural vessels from the CSF by means of a cell layer joined by tight junctions. Outer CSF-brain barrier provides diffusion restriction between brain and subarachnoid CSF through an initial radial glial end feet layer covered with a pial surface layer. To further characterize these interfaces we examined embryonic rat brains from E10 to P0 and forebrains from human embryos and fetuses (6-21st weeks post-conception) and adults using immunohistochemistry and confocal microscopy. Antibodies against claudin-11, BLBP, collagen 1, SSEA-4, MAP2, YKL-40, and its receptor IL-13Rα2 and EAAT1 were used to describe morphological characteristics and functional aspects of the outer brain barriers. Claudin-11 was a reliable marker of the arachnoid blood-CSF barrier. Collagen 1 delineated the subarachnoid space and stained pial surface layer. BLBP defined radial glial end feet layer and SSEA-4 and YKL-40 were present in both leptomeningeal cells and end feet layer, which transformed into glial limitans. IL-13Rα2 and EAAT1 were present in the end feet layer illustrating transporter/receptor presence in the outer CSF-brain barrier. MAP2 immunostaining in adult brain outlined the lower border of glia limitans; remnants of end feet were YKL-40 positive in some areas. We propose that outer brain barriers are composed of at least 3 interfaces: blood-CSF barrier across arachnoid barrier cell layer, blood-CSF barrier across pial microvessels, and outer CSF-brain barrier comprising glial end feet layer/pial surface layer.

  14. Where to restore ecological connectivity? Detecting barriers and quantifying restoration benefits.

    PubMed

    McRae, Brad H; Hall, Sonia A; Beier, Paul; Theobald, David M

    2012-01-01

    Landscape connectivity is crucial for many ecological processes, including dispersal, gene flow, demographic rescue, and movement in response to climate change. As a result, governmental and non-governmental organizations are focusing efforts to map and conserve areas that facilitate movement to maintain population connectivity and promote climate adaptation. In contrast, little focus has been placed on identifying barriers-landscape features which impede movement between ecologically important areas-where restoration could most improve connectivity. Yet knowing where barriers most strongly reduce connectivity can complement traditional analyses aimed at mapping best movement routes. We introduce a novel method to detect important barriers and provide example applications. Our method uses GIS neighborhood analyses in conjunction with effective distance analyses to detect barriers that, if removed, would significantly improve connectivity. Applicable in least-cost, circuit-theoretic, and simulation modeling frameworks, the method detects both complete (impermeable) barriers and those that impede but do not completely block movement. Barrier mapping complements corridor mapping by broadening the range of connectivity conservation alternatives available to practitioners. The method can help practitioners move beyond maintaining currently important areas to restoring and enhancing connectivity through active barrier removal. It can inform decisions on trade-offs between restoration and protection; for example, purchasing an intact corridor may be substantially more costly than restoring a barrier that blocks an alternative corridor. And it extends the concept of centrality to barriers, highlighting areas that most diminish connectivity across broad networks. Identifying which modeled barriers have the greatest impact can also help prioritize error checking of land cover data and collection of field data to improve connectivity maps. Barrier detection provides a different way to view the landscape, broadening thinking about connectivity and fragmentation while increasing conservation options.

  15. Mental illness stigma: concepts, consequences, and initiatives to reduce stigma.

    PubMed

    Rüsch, Nicolas; Angermeyer, Matthias C; Corrigan, Patrick W

    2005-12-01

    Persons with mental illness frequently encounter public stigma and may suffer from self-stigma. This review aims to clarify the concept of mental illness stigma and discuss consequences for individuals with mental illness. After a conceptual overview of stigma we discuss two leading concepts of mental illness stigma and consequences of stigma, focussing on self-stigma/empowerment and fear of stigma as a barrier to using health services. Finally, we discuss three main strategies to reduce stigma -- protest, education, and contact -- and give examples of current anti-stigma campaigns. Well-designed anti-stigma initiatives will help to diminish negative consequences of mental illness stigma.

  16. Shared decision making: relevant concepts and facilitating strategies.

    PubMed

    Bae, Jong-Myon

    2017-01-01

    As the paradigm in healthcare nowadays is the evidence-based, patient-centered decision making, the issue of shared decision making (SDM) is highlighted. The aims of this manuscript were to look at the relevant concepts and suggest the facilitating strategies for overcoming barriers of conducting SDM. While the definitions of SDM were discordant, several concepts such as good communication, individual autonomy, patient participants, and patient-centered decision-making were involved. Further, the facilitating strategies of SDM were to educate and train physician, to apply clinical practice guidelines and patient decision aids, to develop valid measurement tools for evaluation of SDM processes, and to investigate the impact of SDM.

  17. Design and evaluation of active cooling systems for Mach 6 cruise vehicle wings

    NASA Technical Reports Server (NTRS)

    Mcconarty, W. A.; Anthony, F. M.

    1971-01-01

    Active cooling systems, which included transpiration, film, and convective cooling concepts, are examined. Coolants included hydrogen, helium, air, and water. Heat shields, radiation barriers, and thermal insulation are considered to reduce heat flow to the cooling systems. Wing sweep angles are varied from 0 deg to 75 deg and wing leading edge radii of 0.05 inch and 2.0 inches are examined. Structural temperatures are varied to allow comparison of aluminum alloy, titanium alloy, and superalloy structural materials. Cooled wing concepts are compared among themselves, and with the uncooled concept on the basis of structural weight, cooling system weight, and coolant weight.

  18. Combustor concepts for aircraft gas turbine low-power emissions reduction

    NASA Technical Reports Server (NTRS)

    Mularz, E. J.; Gleason, C. C.; Dodds, W. J.

    1978-01-01

    Several combustor concepts were designed and tested to demonstrate significant reductions in aircraft engine idle pollutant emissions. Each concept used a different approach for pollutant reductions: the hot wall combustor employs a thermal barrier coating and impingement cooled liners; the recuperative cooling combustor preheats the air before entering the combustion chamber; and the catalytic converter combustor is composed of a conventional primary zone followed by a catalytic bed for pollutant cleanup. The designs are discussed in detail and test results are presented for a range of aircraft engine idle conditions. The results indicate that ultralow levels of unburned hydrocarbons and carbon monoxide emissions can be achieved.

  19. Agricultural lands preservation: a sociology of survival

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    White, T.S.

    1983-01-01

    This is a rural sociological study investigating the viability of agricultural lands use-values and rural communities in the context of the structure of US agriculture. It outlines the theoretical foundation, ideology, and praxis of a sociology of survival. It is undertaken within the framework of environmental sociology, which focuses on the dynamic interpenetration of social and biotic systems. The concepts of carrying capacity, sustained multiple-use yield, and land-use compatibility and their significance are discussed. The phenomenon of phantom carrying capacity is explored, and its ominous portent noted; but the astonishing potential of agricultural lands to produce huge net gains inmore » use values and in real carrying capacity is affirmed. The theory of unlimited resources, substitution, and market-allocation is falsified. Absolute shortages of renewable and nonrenewable resources are documented, and the necessity for population control, conservation, expanded sustained-yield production, and social allocation is established.« less

  20. Man-Robot Symbiosis: A Framework For Cooperative Intelligence And Control

    NASA Astrophysics Data System (ADS)

    Parker, Lynne E.; Pin, Francois G.

    1988-10-01

    The man-robot symbiosis concept has the fundamental objective of bridging the gap between fully human-controlled and fully autonomous systems to achieve true man-robot cooperative control and intelligence. Such a system would allow improved speed, accuracy, and efficiency of task execution, while retaining the man in the loop for innovative reasoning and decision-making. The symbiont would have capabilities for supervised and unsupervised learning, allowing an increase of expertise in a wide task domain. This paper describes a robotic system architecture facilitating the symbiotic integration of teleoperative and automated modes of task execution. The architecture reflects a unique blend of many disciplines of artificial intelligence into a working system, including job or mission planning, dynamic task allocation, man-robot communication, automated monitoring, and machine learning. These disciplines are embodied in five major components of the symbiotic framework: the Job Planner, the Dynamic Task Allocator, the Presenter/Interpreter, the Automated Monitor, and the Learning System.

  1. The dominance of big pharma: power.

    PubMed

    Edgar, Andrew

    2013-05-01

    The purpose of this paper is to provide a normative model for the assessment of the exercise of power by Big Pharma. By drawing on the work of Steven Lukes, it will be argued that while Big Pharma is overtly highly regulated, so that its power is indeed restricted in the interests of patients and the general public, the industry is still able to exercise what Lukes describes as a third dimension of power. This entails concealing the conflicts of interest and grievances that Big Pharma may have with the health care system, physicians and patients, crucially through rhetorical engagements with Patient Advocacy Groups that seek to shape public opinion, and also by marginalising certain groups, excluding them from debates over health care resource allocation. Three issues will be examined: the construction of a conception of the patient as expert patient or consumer; the phenomenon of disease mongering; the suppression or distortion of debates over resource allocation.

  2. Real-Time Optimization for use in a Control Allocation System to Recover from Pilot Induced Oscillations

    NASA Technical Reports Server (NTRS)

    Leonard, Michael W.

    2013-01-01

    Integration of the Control Allocation technique to recover from Pilot Induced Oscillations (CAPIO) System into the control system of a Short Takeoff and Landing Mobility Concept Vehicle simulation presents a challenge because the CAPIO formulation requires that constrained optimization problems be solved at the controller operating frequency. We present a solution that utilizes a modified version of the well-known L-BFGS-B solver. Despite the iterative nature of the solver, the method is seen to converge in real time with sufficient reliability to support three weeks of piloted runs at the NASA Ames Vertical Motion Simulator (VMS) facility. The results of the optimization are seen to be excellent in the vast majority of real-time frames. Deficiencies in the quality of the results in some frames are shown to be improvable with simple termination criteria adjustments, though more real-time optimization iterations would be required.

  3. Communication on SWIPT and EH Using Electromagnetic Behaviour for Power Allocation in Wireless Networks

    NASA Astrophysics Data System (ADS)

    Khan, Sohel Rana; Ajij, Sayyad

    2017-12-01

    This review paper focuses on the basic relations between wireless power transfer, wireless information transfer and combined phenomenon of simultaneous wireless information and power transfer. The authors reviewed and discussed electromagnetic fields behaviour (EMB) for enhancing the power allocation strategies (PAS) in energy harvesting (EH) wireless communication systems. Further, this paper presents relations between Friis transmission equation and Maxwell's equations to be used in propagation models for reduction in specific absorption rate (SAR). This paper provides a review of various methods and concepts reported in earlier works. This paper also reviews Poynting vector and power densities along with boundary conditions for antennas and human body. Finally, this paper explores the usage of electromagnetic behaviour for the possible enhancement in power saving methods for electromagnetic behaviour centered-wireless energy harvesting (EMBC-WEH). At the same time, possibilities of PAS for reduction in SAR are discussed.

  4. Human-computer interaction for alert warning and attention allocation systems of the multimodal watchstation

    NASA Astrophysics Data System (ADS)

    Obermayer, Richard W.; Nugent, William A.

    2000-11-01

    The SPAWAR Systems Center San Diego is currently developing an advanced Multi-Modal Watchstation (MMWS); design concepts and software from this effort are intended for transition to future United States Navy surface combatants. The MMWS features multiple flat panel displays and several modes of user interaction, including voice input and output, natural language recognition, 3D audio, stylus and gestural inputs. In 1999, an extensive literature review was conducted on basic and applied research concerned with alerting and warning systems. After summarizing that literature, a human computer interaction (HCI) designer's guide was prepared to support the design of an attention allocation subsystem (AAS) for the MMWS. The resultant HCI guidelines are being applied in the design of a fully interactive AAS prototype. An overview of key findings from the literature review, a proposed design methodology with illustrative examples, and an assessment of progress made in implementing the HCI designers guide are presented.

  5. Customer and service profitability

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ballaban, M.; Kelly, K.; Wisniewski, L.

    1996-03-01

    The rapid pace of competitive change in the generation sector has pushed electric utilities to rethink the concept of being obligated to serve all customers and with this change, the notion of measuring customer profitability is also being redefined. Traditionally, uniform services were provided to all customers. Rates were based on each customer classes` contribution to average costs, and consequently return was equally allocated across all customer segments. Profitability was defined strictly on an aggregate basis. The increasing demand for choice by electric customers will require electricity providers to redefine if not who they serve, than certainly how they providemore » differentiated services tailored to specific customer segments. Utilities are beginning to analyze the value, or profitability, of offering these services. Aggregate data no longer provides an accurate assessment of how resources should be allocated most efficiently. As services are unbundled, so too must costs be disaggregated to effectively measure the profitability of various options.« less

  6. Rationing of medical care: Rules of rescue, cost-effectiveness, and the Oregon plan.

    PubMed

    Lamb, Emmet J

    2004-06-01

    Doctors who deal with individual patients fail to avoid interventions with minimal expected benefits. This is one reason that the United States spends more on health care services than any of 28 other industrialized nations. Yet, our money has not bought us health; our infant mortality rate ranks 23rd, and our overall life expectancy rate ranks 20th among the 29 nations. Ours is the only nation without a national health system. Our job-based health insurance system has allowed the number of uninsured persons to reach 44 million, which is 18% of the nonelderly population. This article examines the role of such ethical concepts as beneficence, utilitarianism, and justice in the allocation of health care resources. It also examines the innovative Oregon Health Plan and its use of cost-effectiveness analysis for health care allocation that is based on league tables.

  7. Marrying Hydrological Modelling and Integrated Assessment for the needs of Water Resource Management

    NASA Astrophysics Data System (ADS)

    Croke, B. F. W.; Blakers, R. S.; El Sawah, S.; Fu, B.; Guillaume, J. H. A.; Kelly, R. A.; Patrick, M. J.; Ross, A.; Ticehurst, J.; Barthel, R.; Jakeman, A. J.

    2014-09-01

    This paper discusses the integration of hydrology with other disciplines using an Integrated Assessment (IA) and modelling approach to the management and allocation of water resources. Recent developments in the field of socio-hydrology aim to develop stronger relationships between hydrology and the human dimensions of Water Resource Management (WRM). This should build on an existing wealth of knowledge and experience of coupled human-water systems. To further strengthen this relationship and contribute to this broad body of knowledge, we propose a strong and durable "marriage" between IA and hydrology. The foundation of this marriage requires engagement with appropriate concepts, model structures, scales of analyses, performance evaluation and communication - and the associated tools and models that are needed for pragmatic deployment or operation. To gain insight into how this can be achieved, an IA case study in water allocation in the Lower Namoi catchment, NSW, Australia is presented.

  8. Off-Axis Driven Current Effects on ETB and ITB Formations based on Bifurcation Concept

    NASA Astrophysics Data System (ADS)

    Pakdeewanich, J.; Onjun, T.; Chatthong, B.

    2017-09-01

    This research studies plasma performance in fusion Tokamak system by investigating parameters such as plasma pressure in the presence of an edge transport barrier (ETB) and an internal transport barrier (ITB) as the off-axis driven current position is varied. The plasma is modeled based on the bifurcation concept using a suppression function that can result in formation of transport barriers. In this model, thermal and particle transport equations, including both neoclassical and anomalous effects, are solved simultaneously in slab geometry. The neoclassical coefficients are assumed to be constant while the anomalous coefficients depend on gradients of local pressure and density. The suppression function, depending on flow shear and magnetic shear, is assumed to affect only on the anomalous channel. The flow shear can be calculated from the force balance equation, while the magnetic shear is calculated from the given plasma current. It is found that as the position of driven current peak is moved outwards from the plasma center, the central pressure is increased. But at some point it stars to decline, mostly when the driven current peak has reached the outer half of the plasma. The higher pressure value results from the combination of ETB and ITB formations. The drop in central pressure occurs because ITB stats to disappear.

  9. Promotion of oral health by community nurses.

    PubMed

    Garry, Brendan; Boran, Sue

    2017-10-02

    To explore the enablers and barriers perceived by community nurses in the promotion of oral health in an adult community trust directorate. Oral health care promotion in community care settings is being neglected. England and Wales have witnessed marked improvements in periodontal disease; however, no improvements have been seen in older people. A qualitative methodology was employed, where eight nurses from Band 5 to 7 were interviewed using a semi-structured approach. The data was analysed thematically. Data analysis was organised into four themes: professional self-concept and the development of knowledge, skills and attitudes necessary in the promotion of oral health; the impact an organisation has on the promotion of oral health and an exploration of the enablers and barriers identified by the community nurses while delivering care; the relationships between the nurse and patient and the potential impact on oral health promotion; the concept of self-regard in relation to the promotion of oral health and its overall impact. A commitment to improving oral health and requests for additional educational input were apparent. Organisational enablers and barriers were identified, alongside the crucial role a positive self-regard for oral health care may play in the promotion of oral health. Nurses need relevant education, organisational support, adequate resources and support from a multidisciplinary team to deliver optimal oral health promotion.

  10. Cryopreservation by vitrification: a promising approach for transplant organ banking.

    PubMed

    Finger, Erik B; Bischof, John C

    2018-06-01

    The objective of this review is to describe the physical and biological barriers to organ cryopreservation, historic approaches for conventional cryopreservation and evolving techniques for ice-free cryopreservation by vitrification. Vitrification is a process whereby a biologic substance is cooled to cryogenic temperatures without the destructive phase transition of liquid to solid ice. Recent advances in cryoprotective solutions, organ perfusion techniques and novel heating technologies have demonstrated the potential for vitrification and rewarming organs on a scale applicable for human transplantation. Successful strategies for organ cryopreservation could enable organ banking, which would recast the entire process in which organs are recovered, allocated, stored and prepared for transplant.

  11. Effect of task load and task load increment on performance and workload

    NASA Technical Reports Server (NTRS)

    Hancock, P. A.; Williams, G.

    1993-01-01

    The goal of adaptive automated task allocation is the 'seamless' transfer of work demand between human and machine. Clearly, at the present time, we are far from this objective. One of the barriers to achieving effortless human-machine symbiosis is an inadequate understanding of the way in which operators themselves seek to reallocate demand among their own personal 'resources.' The paper addresses this through an examination of workload response, which scales an individual's reaction to common levels of experienced external demand. The results indicate the primary driver of performance is the absolute level of task demand over the increment in that demand.

  12. A Non Rigid Reusable Surface Insulation Concept for the Space Shuttle Thermal Protection System

    NASA Technical Reports Server (NTRS)

    Alexander, J. G.

    1973-01-01

    A reusable thermal protection system concept was developed for the space shuttle that utilizes a flexible, woven ceramic mat insulation beneath an aerodynamic skin and moisture barrier consisting of either a dense ceramic coating or a super alloy metallic foil. The resulting heat shield material has unique structural characteristics. The shear modulus of the woven mat is very low such that bending and membrane loads introduced into the underlying structural panel remain isolated from the surface skin.

  13. Independent technical support for the frozen soil barrier installation and operation at the Fukushima Daiichi Nuclear Power Station (F1 Site)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Looney, Brian B.; Jackson, Dennis G.; Truex, Michael J.

    TEPCO is implementing a number of water countermeasures to limit the releases and impacts of contaminated water to the surrounding environment. The diverse countermeasures work together in an integrated manner to provide different types, and several levels, of protection. In general, the strategy represents a comprehensive example of a “defense in depth” concept that is used for nuclear facilities around the world. One of the key countermeasures is a frozen soil barrier encircling the damaged reactor facilities. The frozen barrier is intended to limit the flow of water into the area and provide TEPCO the ability to reduce the amountmore » of contaminated water that requires treatment and storage. The National Laboratory team supports the selection of artificial ground freezing and the incorporation of the frozen soil barrier in the contaminated water countermeasures -- the technical characteristics of a frozen barrier are relatively well suited to the Fukushima-specific conditions and the need for inflow reduction. Further, our independent review generally supports the TEPCO/Kajima design, installation strategy and operation plan.« less

  14. Challenges in Commercializing Biomimetic Membranes

    PubMed Central

    Perry, Mark; Madsen, Steen Ulrik; Jørgensen, Tine; Braekevelt, Sylvie; Lauritzen, Karsten; Hélix-Nielsen, Claus

    2015-01-01

    The discovery of selective water channel proteins—aquaporins—has prompted growing interest in using these proteins, as the building blocks for designing new types of membranes. However, as with any other new and potentially disruptive technology, barriers for successful market entry exist. One category includes customer-related barriers, which can be influenced to some extent. Another category includes market-technical-related barriers, which can be very difficult to overcome by an organization/company aiming at successfully introducing their innovation on the market—in particular if both the organization and the technology are at early stages. Often, one faces barriers from both these categories at the same time, which makes it necessary to gain insight of the particular market when introducing a new innovative product. In this review we present the basic concepts and discuss some of these barriers and challenges associated with introducing biomimetic aquaporin membranes. These include technical issues in membrane production and product testing. Then we discuss possible business models for introducing new technologies in general, followed by a presentation of beach-head market segments relevant for biomimetic aquaporin membranes. PMID:26556379

  15. Challenges in Commercializing Biomimetic Membranes.

    PubMed

    Perry, Mark; Madsen, Steen Ulrik; Jørgensen, Tine; Braekevelt, Sylvie; Lauritzen, Karsten; Hélix-Nielsen, Claus

    2015-11-05

    The discovery of selective water channel proteins-aquaporins-has prompted growing interest in using these proteins, as the building blocks for designing new types of membranes. However, as with any other new and potentially disruptive technology, barriers for successful market entry exist. One category includes customer-related barriers, which can be influenced to some extent. Another category includes market-technical-related barriers, which can be very difficult to overcome by an organization/company aiming at successfully introducing their innovation on the market-in particular if both the organization and the technology are at early stages. Often, one faces barriers from both these categories at the same time, which makes it necessary to gain insight of the particular market when introducing a new innovative product. In this review we present the basic concepts and discuss some of these barriers and challenges associated with introducing biomimetic aquaporin membranes. These include technical issues in membrane production and product testing. Then we discuss possible business models for introducing new technologies in general, followed by a presentation of beach-head market segments relevant for biomimetic aquaporin membranes.

  16. Exploring Concepts of Operations for On-Demand Passenger Air Transportation

    NASA Technical Reports Server (NTRS)

    Nneji, Victoria Chibuogu; Stimpson, Alexander; Cummings, Mary; Goodrich, Kenneth H.

    2017-01-01

    In recent years, a surge of interest in "flying cars" for city commutes has led to rapid development of new technologies to help make them and similar on-demand mobility platforms a reality. To this end, this paper provides analyses of the stakeholders involved, their proposed operational concepts, and the hazards and regulations that must be addressed. Three system architectures emerged from the analyses, ranging from conventional air taxi to revolutionary fully autonomous aircraft operations, each with vehicle safety functions allocated differently between humans and machines. Advancements for enabling technologies such as distributed electric propulsion and artificial intelligence have had major investments and initial experimental success, but may be some years away from being deployed for on-demand passenger air transportation at scale.

  17. [Basic principles and methodological considerations of health economic evaluations].

    PubMed

    Loza, Cesar; Castillo-Portilla, Manuel; Rojas, José Luis; Huayanay, Leandro

    2011-01-01

    Health Economics is an essential instrument for health management, and economic evaluations can be considered as tools assisting the decision-making process for the allocation of resources in health. Currently, economic evaluations are increasingly being used worldwide, thus encouraging evidence-based decision-making and seeking efficient and rational alternatives within the framework of health services activities. In this review, we present an overview and define the basic types of economic evaluations, with emphasis on complete Economic Evaluations (EE). In addition, we review key concepts regarding the perspectives from which EE can be conducted, the types of costs that can be considered, the time horizon, discounting, assessment of uncertainty and decision rules. Finally, we describe concepts about the extrapolation and spread of economic evaluations in health.

  18. Water conservation and reform of the prior appropriation doctrine in Colorado

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wescoat, J.L. Jr.

    The prior appropriation doctrine has come under criticism for impeding both the efficient allocation of water and the adoption of water conservation improvements. Analysis of water rights statutes and case law revealed the following opportunities for evolutionary reform of the appropriation doctrine in Colorado: more precise definition of key property rights concepts (such as beneficial use, waste and duty of water); improved public administration (e.g., in record-keeping and analysis of water use patterns); and organizational adjustments to reduce transaction costs and strategic behavior. Integration of vested rights with the concept of maximum beneficial use will depend upon such creative adjustmentsmore » in public and private institutions for water management. 32 references, 3 figures, 4 tables.« less

  19. Prefocal station mechanical design concept study for the E-ELT

    NASA Astrophysics Data System (ADS)

    Jolley, Paul; Brunetto, Enzo; Frank, Christoph; Lewis, Steffan; Marchetti, Enrico

    2016-07-01

    The Nasmyth platforms of the E-ELT will contain one Prefocal Station (PFS) each. The main PFS functional requirements are to provide a focal plane to the three Nasmyth focal stations and the Coudé focus, optical sensing supporting telescope low order optimisation and seeing limited image quality, and optical sensing supporting characterising and phasing of M1 and other telescope subsystems. The PFS user requirements are used to derive the PFS technical requirements specification that will form the basis for design, development and production of the system. This specification process includes high-level architectural decisions and technical performance budget allocations. The mechanical design concepts reported here have been developed in order to validate key system specifications and associated technical budgets.

  20. Concept of Operations for RCO SPO

    NASA Technical Reports Server (NTRS)

    Matessa, Michael; Strybel, Thomas; Vu, Kim; Battiste, Vernol; Schnell, Thomas

    2017-01-01

    Reduced crew operations (RCO) refers to the reduction of crew members flying long-haul or military operations with more than one pilot onboard. Single pilot operations (SPO) refers to flying a commercial transport aircraft with only one pilot on board the aircraft, assisted by advanced onboard automation andor ground operators providing piloting support services. Properly implemented, RCO/SPO could provide operating cost savings while maintaining a level of safety no less than conventional two-pilot commercial operations. A concept of operations (ConOps) for any paradigm describes the characteristics of its various components and their integration in a multi-dimensional design space. This paper presents key options for humanautomation function allocation being considered by NASA in its ongoing development of RCO/SPO ConOps.

  1. Satellite-aided mobile radio concepts study: Concept definition of a satellite-aided mobile and personal radio communication system

    NASA Technical Reports Server (NTRS)

    Anderson, R. E.

    1979-01-01

    The satellite system requires the use of a large satellite antenna and spacecraft array power of about 12 kW or more depending on the operating frequency. Technology developments needed include large offset reflector multibeam antennas, satellite electrical power sybsystems providing greater than 12 kW of power, signal switching hardware, and linearized efficient solid state amplifiers for the satellite-aided mobile band. Presently there is no frequency assignment for this service, and it is recommended that an allocation be pursued. The satellite system appears to be within reasonable extrapolation of the state of the art. It is further recommended that the satellite-aided system spacecraft definition studies and supporting technology development be initiated.

  2. A system for the simulation and evaluation of satellite communication networks

    NASA Technical Reports Server (NTRS)

    Bagwell, J. W.

    1983-01-01

    With the emergence of a new era in satellite communications brought about by NASA's thrust into the Ka band with multibeam and onboard processing technologies, new and innovative techniques for evaluating these concepts and systems are required. To this end, NASA, in conjunction with its extensive program for advanced communications technology development, has undertaken to develop a concept for the simulation and evaluation of a complete communications network. Incorporated in this network will be proof of concept models of the latest technologies proposed for future satellite communications systems. These include low noise receivers, matrix switches, baseband processors, and solid state and tube type high power amplifiers. To accomplish this, numerous supporting technologies must be added to those aforementioned proof of concept models. These include controllers for synchronization, order wire, and resource allocation, gain compensation, signal leveling, power augmentation, and rain fade and range delay simulation. Taken together, these will be assembled to comprise a system capable of addressing numerous design and performance questions. The simulation and evaluation system as planned will be modular in design and implementation, capable of modification and updating to track and evaluate a continuum emerging concepts and technologies.

  3. A Facilities Manager's Guide to Green Building Design.

    ERIC Educational Resources Information Center

    Simpson, Walter

    2001-01-01

    Explains how the "green building" approach to educational facilities design creates healthy, naturally lit, attractive buildings with lower operating and life cycle costs. Tips on getting started on a green design and overcoming the barriers to the green design concept are discussed. (GR)

  4. Belonging: Blurring the Boundaries

    ERIC Educational Resources Information Center

    Meharg, Debbie; Craighill, Stephanie; Varey, Alison; Cairncross, Sandra

    2017-01-01

    This paper applies Whitchurch's (2008) concept of the "third space" to the emergent territory occupied by further education college students as they "cross the boundary" to continue their studies at the university. Findings reveal that these transitioning students face barriers to success, feelings of being isolated and…

  5. MATCON MODIFIED ASPHALT CONTAINMENT SYSTEM FOR MULTI-USE BROWNFIELDS

    EPA Science Inventory

    The concept of putting brownfield real estate back into safe and practical use is very appealing o both the owner and the neighborhood. Environmental regulations often preclude multi-use alterantives because traditional containment solutions rely on water barrier covers. These ar...

  6. A Customized Transportation Intervention for Persons with Visual Impairments

    ERIC Educational Resources Information Center

    Crudden, Adele; Antonelli, Karla; O'Mally, Jamie

    2017-01-01

    Introduction: Transportation can be an employment barrier for persons with disabilities, particularly those with visual impairments. A customized transportation intervention for people with visual impairments, based on concepts associated with customized employment, was devised, implemented, and evaluated. Methods: A pretest and posttest…

  7. NASA Unmanned Aircraft (UA) Control and Non-Payload Communication (CNPC) System Waveform Trade Studies

    NASA Technical Reports Server (NTRS)

    Chavez, Carlos; Hammel, Bruce; Hammel, Allan; Moore, John R.

    2014-01-01

    Unmanned Aircraft Systems (UAS) represent a new capability that will provide a variety of services in the government (public) and commercial (civil) aviation sectors. The growth of this potential industry has not yet been realized due to the lack of a common understanding of what is required to safely operate UAS in the National Airspace System (NAS). To address this deficiency, NASA has established a project called UAS Integration in the NAS (UAS in the NAS), under the Integrated Systems Research Program (ISRP) of the Aeronautics Research Mission Directorate (ARMD). This project provides an opportunity to transition concepts, technology, algorithms, and knowledge to the Federal Aviation Administration (FAA) and other stakeholders to help them define the requirements, regulations, and issues for routine UAS access to the NAS. The safe, routine, and efficient integration of UAS into the NAS requires new radio frequency (RF) spectrum allocations and a new data communications system which is both secure and scalable with increasing UAS traffic without adversely impacting the Air Traffic Control (ATC) communication system. These data communications, referred to as Control and Non-Payload Communications (CNPC), whose purpose is to exchange information between the unmanned aircraft and the ground control station to ensure safe, reliable, and effective unmanned aircraft flight operation. A Communications Subproject within the UAS in the NAS Project has been established to address issues related to CNPC development, certification and fielding. The focus of the Communications Subproject is on validating and allocating new RF spectrum and data link communications to enable civil UAS integration into the NAS. The goal is to validate secure, robust data links within the allocated frequency spectrum for UAS. A vision, architectural concepts, and seed requirements for the future commercial UAS CNPC system have been developed by RTCA Special Committee 203 (SC-203) in the process of determining formal recommendations to the FAA in its role provided for under the Federal Advisory Committee Act. NASA intends to conduct its research and development in keeping with this vision and associated architectural concepts. The prototype communication systems developed and tested by NASA will be used to validate and update the initial SC-203 requirements in order to provide a foundation for SC-203's Minimum Aviation System Performance Standards (MASPS).

  8. Biological hydrogels as selective diffusion barriers.

    PubMed

    Lieleg, Oliver; Ribbeck, Katharina

    2011-09-01

    The controlled exchange of molecules between organelles, cells, or organisms and their environment is crucial for life. Biological gels such as mucus, the extracellular matrix (ECM), and the biopolymer barrier within the nuclear pore are well suited to achieve such a selective exchange, allowing passage of particular molecules while rejecting many others. Although hydrogel-based filters are integral parts of biology, clear concepts of how their barrier function is controlled at a microscopic level are still missing. We summarize here our current understanding of how selective filtering is established by different biopolymer-based hydrogels. We ask if the modulation of microscopic particle transport in biological hydrogels is based on a generic filtering principle which employs biochemical/biophysical interactions with the filtered molecules rather than size-exclusion effects. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Where to Restore Ecological Connectivity? Detecting Barriers and Quantifying Restoration Benefits

    PubMed Central

    McRae, Brad H.; Hall, Sonia A.; Beier, Paul; Theobald, David M.

    2012-01-01

    Landscape connectivity is crucial for many ecological processes, including dispersal, gene flow, demographic rescue, and movement in response to climate change. As a result, governmental and non-governmental organizations are focusing efforts to map and conserve areas that facilitate movement to maintain population connectivity and promote climate adaptation. In contrast, little focus has been placed on identifying barriers—landscape features which impede movement between ecologically important areas—where restoration could most improve connectivity. Yet knowing where barriers most strongly reduce connectivity can complement traditional analyses aimed at mapping best movement routes. We introduce a novel method to detect important barriers and provide example applications. Our method uses GIS neighborhood analyses in conjunction with effective distance analyses to detect barriers that, if removed, would significantly improve connectivity. Applicable in least-cost, circuit-theoretic, and simulation modeling frameworks, the method detects both complete (impermeable) barriers and those that impede but do not completely block movement. Barrier mapping complements corridor mapping by broadening the range of connectivity conservation alternatives available to practitioners. The method can help practitioners move beyond maintaining currently important areas to restoring and enhancing connectivity through active barrier removal. It can inform decisions on trade-offs between restoration and protection; for example, purchasing an intact corridor may be substantially more costly than restoring a barrier that blocks an alternative corridor. And it extends the concept of centrality to barriers, highlighting areas that most diminish connectivity across broad networks. Identifying which modeled barriers have the greatest impact can also help prioritize error checking of land cover data and collection of field data to improve connectivity maps. Barrier detection provides a different way to view the landscape, broadening thinking about connectivity and fragmentation while increasing conservation options. PMID:23300719

  10. Natural conception rates in couples with unexplained or mild male subfertility scheduled for fertility treatment: a secondary analysis of a randomized controlled trial.

    PubMed

    van Eekelen, R; Tjon-Kon-Fat, R I; Bossuyt, P M M; van Geloven, N; Eijkemans, M J C; Bensdorp, A J; van der Veen, F; Mol, B W; van Wely, M

    2018-05-01

    What is the natural conception rate over the course of 12 months in couples with unexplained or mild male subfertility who are scheduled for fertility treatment and have a predicted unfavourable prognosis for natural conception? The natural conception rate over the course of 12 months in couples who were allocated to treatment was estimated to be 24.5% (95% CI: 20-29%). After starting treatment, couples often perceive unsuccessful cycles as evidence of definitive failure even though they are still able to conceive naturally in between and after treatment. The magnitude of the natural conception rate for couples who chose to commence treatment is unknown, as is whether the calculated prognosis before commencing treatment is still applicable. We performed a secondary analysis of a randomized controlled trial including couples with unexplained or mild male subfertility and an unfavourable prognosis for natural conception. Couples were allocated to either three cycles IVF with single embryo transfer (SET), six cycles of IVF in a modified natural cycle (MNC) or six cycles of IUI with controlled ovarian hyperstimulation (IUI-COH). The detailed data collection in this trial allowed us to study the conception rates in periods that couples were not receiving treatment. We split the dataset into periods during which couples were treated and periods during which they were not treated. Couples could conceive naturally in the periods before, in between and after treatment cycles. The outcome was ongoing pregnancy, thus natural conception rate refers to natural conception leading to ongoing pregnancy. We performed a Cox proportional hazards analysis with female age, duration of subfertility and a time-varying covariate with four categories: IVF-SET, IVF-MNC, IUI-COH and no treatment. We used this Cox model to estimate the natural conception rate over 12 months of no treatment. Out of 602 included couples, there were 342 ongoing pregnancies, of which 77 (23%) resulted from natural conception. The estimated natural conception rate over 12 months was 24.5% (95% CI: 20-29%) on cohort level. Estimated rates for female age varying between 18 and 38 years and duration of subfertility between 1 and 3 years ranged from 22 to 35%. We considered couples at risk for natural conception when not receiving treatment, whereas they might not have had periovulatory sexual intercourse. As couples were scheduled for treatment, it is possible that these couples were less inclined to try to conceive naturally, potentially leading to an underestimation of their natural conception rate if they kept trying to conceive. Couples with unexplained subfertility who are about to start fertility treatment, still have about a one in four chance of ongoing pregnancy due to natural conception over 12 months. This information can add to the counselling of couples who commenced fertility treatment after failed cycles and to emphasize not to cease their natural attempts. The INeS trial was supported by a grant from ZonMW, the Dutch Organization for Health Research and Development (120620027), and a grant from Zorgverzekeraars Nederland, the Dutch association of health care insurers (09-003). The funders had no role in study design, collection, analysis and interpretation of the data. B.W.M. is supported by a NHMRC Practitioner Fellowship (GNT1082548). B.W.M. reports consultancy for ObsEva, Merck and Guerbet. No other potential conflicts of interest reported. The INeS trial was registered at the Dutch trial registry (NTR 939).

  11. Promoting youth physical activity in rural southern communities: practitioner perceptions of environmental opportunities and barriers.

    PubMed

    Edwards, Michael B; Theriault, Daniel S; Shores, Kindal A; Melton, Karen M

    2014-01-01

    Research on youth physical activity has focused on urban areas. Rural adolescents are more likely to be physically inactive than urban youth, contributing to higher risk of obesity and chronic diseases. Study objectives were to: (1) identify perceived opportunities and barriers to youth physical activity within a rural area and (2) identify rural community characteristics that facilitate or inhibit efforts to promote youth physical activity. Thirty in-depth interviews were conducted with expert informants in 2 rural southern US counties. Interviewees were recruited from diverse positions across multiple sectors based on their expert knowledge of community policies and programs for youth physical activity. Informants saw ball fields, natural amenities, and school sports as primary resources for youth physical activity, but they were divided on whether opportunities were abundant or scarce. Physical distance, social isolation, lack of community offerings, and transportation were identified as key barriers. Local social networks facilitated political action and volunteer recruitment to support programs. However, communities often lacked human capital to sustain initiatives. Racial divisions influenced perceptions of opportunities. Despite divisions, there were also examples of pooling resources to create and sustain physical activity opportunities. Developing partnerships and leveraging local resources may be essential to overcoming barriers for physical activity promotion in rural areas. Involvement of church leaders, school officials, health care workers, and cooperative extension is likely needed to establish and sustain youth rural physical activity programs. Allocating resources to existing community personnel and volunteers for continuing education may be valuable. © 2014 National Rural Health Association.

  12. Acknowledging and allocating responsibility for clinical inertia in the management of Type 2 diabetes in primary care: a qualitative study.

    PubMed

    Zafar, A; Stone, M A; Davies, M J; Khunti, K

    2015-03-01

    Failure to intensify treatment in patients with Type 2 diabetes with suboptimal blood glucose control has been termed clinical inertia and has been shown to contribute to poorer patient outcomes. We aimed to identify and explore perceptions about clinical inertia from the perspective of primary healthcare providers. A qualitative study was conducted in Leicestershire and Northamptonshire, UK. Purposive sampling was based on healthcare providers working in primary care settings with 'higher' and 'lower' target achievement based on routine data. Twenty semi-structured interviews were conducted, face-to-face or by telephone. Thematic analysis was informed by the constant comparative approach. An important broad theme that emerged during the analysis was related to attribution and explanation of responsibility for clinical inertia. This included general willingness to accept a degree of responsibility for clinical inertia. In some cases, however, participants had inaccurate perceptions about levels of target achievement in their primary care centres, as indicated by routine data. Participants sought to lessen their own sense of accountability by highlighting patient-level barriers such as comorbidities and human fallibility, and also system-level barriers, particularly time constraints. Perceptions about ways of addressing the problem of clinical inertia were not seen as straightforward, further emphasizing a complex and cumulative pattern of barriers. In order to understand and address the problem of clinical inertia, provider, patient- and system-level barriers should be considered together rather than as separate issues. Acknowledgement of responsibility should be regarded positively as a motivator for change. © 2014 The Authors. Diabetic Medicine © 2014 Diabetes UK.

  13. The egg-sharing model for human therapeutic cloning research: managing donor selection criteria, the proportion of shared oocytes allocated to research, and amount of financial subsidy given to the donor.

    PubMed

    Heng, Boon Chin; Tong, Guo Qing; Stojkovic, Miodrag

    2006-01-01

    Recent advances in human therapeutic cloning made by Hwang and colleagues have opened up new avenues of therapy for various human diseases. However, the major bottleneck of this new technology is the severe shortage of human donor oocytes. Egg-sharing in return for subsidized fertility treatment has been suggested as an ethically justifiable and practical solution to overcome the shortage of donor oocytes for therapeutic cloning. Because the utilization of shared oocytes in therapeutic cloning research does not result in any therapeutic benefit to a second party, this would necessitate a different management strategy compared to their use for the assisted conception of infertile women who are unable to produce any oocytes of their own. It is proposed that the pool of prospective egg-sharers in therapeutic cloning research be limited only to younger women (below 30 years of age) with indications for either male partner sub-fertility or tubal blockage. With regards to the proportion of the shared gametes being allocated to research, a threshold number of retrieved oocytes should be set that if not exceeded, would result in the patient being automatically removed from the egg-sharing scheme. Any excess supernumerary oocyte above this threshold number can be contributed to science, and allocation should be done in a randomized manner. Perhaps, a total of 10 retrieved oocytes from the patient may be considered a suitable threshold, since the chances of conception are unlikely to be impaired. With regards to the amount of subsidy being given to the patient, it is suggested that the proportion of financial subsidy should be equal to the proportion of the patient's oocytes being allocated to research. No doubt, the promise of future therapeutic benefit may be offered to the patient instead of financial subsidy. However, this is ethically controversial because therapeutic cloning has not yet been demonstrated to be a viable model of clinical therapy and any promises made to the patient might turn out to be illusionary. Hence, it is proposed that a tangible financial subsidy on the medical fees might be the better option for the patient's welfare.

  14. Concept for a Wireless Sensor Network to support GIS based water and land resource management in the Aksu-Tarim Basin, Xinjiang, China

    NASA Astrophysics Data System (ADS)

    Doluschitz, Reiner; Feike, Til

    2013-04-01

    Farmers in the oases along the Aksu-Tarim River suffer from severe seasonal water shortage caused by high fluctuations of river run-off. The uncertainty of water availability makes the planning of crop production and related investments extremely difficult. As a consequence farm management is often sub-optimal, manifesting in low input efficiencies, and the value generated in the agricultural sector being way below its potential. The "Tarim Basin Water Resource Bureau" (TBWRB) was founded in the 1990s. Its major task is to implement a basin wide water resources management plan, which involves fair allocation of water resources among the farmers in the different administrative units along the river. Among others, the lack of reliable and timely information on water quantities and qualities within the major water bodies of the basin hinders the implementation of an effective water management plan. Therefore we introduce the concept of a wireless sensor network (WSN) that provides reliable instantaneous information on the status of all important water resources within the basin. In the first step a GIS including all vital geospatial data, like river courses, channel and reservoir network and capacities, soil and land use map, is built. In the second step a WSN that monitors all important parameters at essential positions throughout the basin needs to be established. Measured parameters comprise meteorological data, river run-off, water levels of reservoirs, groundwater levels, and salinity levels of water resources. All data is centrally collected and processed by the TBWRB. Apart from generating a prompt and complete picture of currently available water resources, the TBWRB can use the system to record actual water allocation, and develop an early warning system for upcoming droughts or floods. Finally an integrated water and land management scheme can be established that allocates resources maximizing the benefits at basin level. Financed by public funding, the data collected by the WSN should be accessible to the public. Considering the environmental, economic and social cost of inefficient, intransparent and unfair allocation of water resources, the investments into a WSN are reasonable. However, it requires strong efforts from highest governmental agencies to enable the TBWRB to compile all the required data (e.g. meteorological, soil, river run-off), which is customarily collected and controlled by the respective administrative unit.

  15. STS payloads mission control study continuation phase A-1. Volume 2-C, task 3: Identification of joint activities and estimation of resources in preparation for joint flight operations

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Payload mission control concepts are developed for real time flight operations of STS. Flight planning, training, simulations, and other flight preparations are included. Payload activities for the preflight phase, activity sequences and organizational allocations, and traffic and experience factors to establish composite man-loading for joint STS payload activities are identified for flight operations from 1980 to 1985.

  16. Space station operations task force. Panel 3 report: User development and integration

    NASA Technical Reports Server (NTRS)

    1987-01-01

    The User Development and Integration Panel of the Space Station Operations Task Force was chartered to develop concepts relating to the operations of the Space Station manned base and the platforms, user accommodation and integration activities. The needs of the user community are addressed in the context with the mature operations phase of the Space Station. Issues addressed include space station pricing options, marketing strategies, payload selection and resource allocation options, and manifesting techniques.

  17. The MOD-1 steel blade

    NASA Technical Reports Server (NTRS)

    Vanbronkhorst, J.

    1979-01-01

    The design, development, fabrication, testing, and transport of two 100 foot metal blades for the MOD-1 WTS are summarized. Because the metal blade design was started late in the MOD-1 system development, many of the design requirements (allocations) were restrictive for the metal blade concept, particularly the maximum weight requirement. The design solutions required to achieve the weight goal resulted in a labor intensive (expensive) fabrication, particularly for a quantity of only two blades manufactured using minimal tooling.

  18. Implementation of GAMMON - An efficient load balancing strategy for a local computer system

    NASA Technical Reports Server (NTRS)

    Baumgartner, Katherine M.; Kling, Ralph M.; Wah, Benjamin W.

    1989-01-01

    GAMMON (Global Allocation from Maximum to Minimum in cONstant time), an efficient load-balancing algorithm, is described. GAMMON uses the available broadcast capability of multiaccess networks to implement an efficient search technique for finding hosts with maximal and minimal loads. The search technique has an average overhead which is independent of the number of participating stations. The transition from the theoretical concept to a practical, reliable, and efficient implementation is described.

  19. Look Up for Healing: Embodiment of the Heal Concept in Looking Upward.

    PubMed

    Leitan, N D; Williams, B; Murray, G

    2015-01-01

    Conceptual processing may not be restricted to the mind. The heal concept has been metaphorically associated with an "up" bodily posture. Perceptual Symbol Systems (PSS) theory suggests that this association is underpinned by bodily states which occur during learning and become instantiated as the concept. Thus the aim of this study was to examine whether processing related to the heal concept is promoted by priming the bodily state of looking upwards. We used a mixed 2x2 priming paradigm in which 58 participants were asked to evaluate words as either related to the heal concept or not after being primed to trigger the concept of looking up versus down (Direction--within subjects). A possible dose-response effect of priming was investigated via allocating participants to two 'strengths' of prime, observing an image of someone whose gaze was upward/downward (low strength) and observing an image of someone whose gaze was upward/downward while physically tilting their head upwards or downwards in accord with the image (high strength) (Strength--between subjects). Participants responded to words related to heal faster than words unrelated to heal across both "Strength" conditions. There was no evidence that priming was stronger in the high strength condition. The present study found that, consistent with a PSS view of cognition, the heal concept is embodied in looking upward, which has important implications for cognition, general health, health psychology, health promotion and therapy.

  20. Concept-Based Curricula: A National Study of Critical Concepts.

    PubMed

    Brussow, Jennifer A; Roberts, Karin; Scaruto, Matthew; Sommer, Sheryl; Mills, Christine

    2018-02-22

    As nursing education struggles to address a rapidly changing health care system, overcrowded curricula, and an increased focus on clinical reasoning skills, many programs have adopted or transitioned to concept-based curricula (CBCs), which are structured around key concepts and exemplars. Despite CBC's promised benefits, the process of developing a CBC framework may pose a challenge to programs. To address this barrier, a national study was conducted to develop a representative list of concepts and exemplars. This initiative expands on prior work by suggesting a leveled approach to positioning exemplars within a curricular sequence.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

  1. Deaf: A Concept Analysis From a Cultural Perspective Using the Wilson Method of Concept Analysis Development.

    PubMed

    Pendergrass, Kathy M; Newman, Susan D; Jones, Elaine; Jenkins, Carolyn H

    2017-07-01

    The purpose of this article is to provide an analysis of the concept Deaf to increase health care provider (HCP) understanding from a cultural perspective. Deaf signers, people with hearing loss who communicate primarily in American Sign Language (ASL), generally define the term Deaf as a cultural heritage. In the health care setting, the term deaf is most often defined as a pathological condition requiring medical intervention. When HCPs are unaware that there are both cultural and pathological views of hearing loss, significant barriers may exist between the HCP and the Deaf individual. The concept of Deaf is analyzed using the Wilsonian method. Essential elements of the concept "Deaf" from a cultural perspective include a personal choice to communicate primarily in ASL and identify with the Deaf community. Resources for HCPs are needed to quickly identify Deaf signers and provide appropriate communication.

  2. Marketing Across Cultures: Issues, Problems and Opportunities.

    ERIC Educational Resources Information Center

    Abdrabboh, Bob

    Now more than ever, a clear knowledge and understanding of languages, cultures, and customs is essential to successfully marketing products and services around the world. Barriers to competition may occur in differences in language, technology levels, conceptions of authority, environmental perceptions, contexting, and social organization. In…

  3. Communication: Concepts and Processes.

    ERIC Educational Resources Information Center

    DeVito, Joseph A.

    A mixture of theoretical and practical essays points up the purposes of, barriers to, and means of facilitating communication. Four models of how people communicate are presented. A series of essays describing communication messages and channels include considerations of "gobbledygook," nonverbal communication by touch, smell, or body movement,…

  4. 10 CFR 63.102 - Concepts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... appropriate; and the sealing of shafts, ramps, and boreholes. (d) Areas related to isolation. Although the... geologic setting that provides isolation of the radioactive waste, make up the geologic repository. (e... will be capable of contributing to the isolation of radioactive waste and thus be a barrier important...

  5. 10 CFR 63.102 - Concepts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... appropriate; and the sealing of shafts, ramps, and boreholes. (d) Areas related to isolation. Although the... geologic setting that provides isolation of the radioactive waste, make up the geologic repository. (e... will be capable of contributing to the isolation of radioactive waste and thus be a barrier important...

  6. Fuel, environmental, and transmission pricing considerations in a deregulated environment

    NASA Astrophysics Data System (ADS)

    Obessis, Emmanouil Vlassios

    The 1992 National Energy Policy Act drastically changed the traditional structure of the vertically integrated utility. To facilitate increased competition in the power utility sector, all markets related to power generation have been opened to free competition and trading. To survive in the new competitive environment, power producers need to reduce costs and increase efficiency. Fuel marketing strategies are thus, getting more aggressive and fuel markets are becoming more competitive, offering more options regarding fuel supplies and contracts. At the same time, the 1990 Clean Air Act Amendments are taking effect. Although tightening the emission standards, this legislation offers utilities a wider flexibility in choosing compliance strategies. It also set maximum annual allowable levels replacing the traditional uniform maximum emission rates. The bill also introduced the concept of marketable emission allowances and provided for the establishment of nationwide markets where allowances may be traded, sold, or purchased. Several fuel- and emission-constrained algorithms have been historically presented, but those two classes of constraints, in general, were handled independently. The multiobjective optimization model developed in this research work, concurrently satisfies sets of detailed fuel and emission limits, modeling in a more accurate way the fuel supply and environmental limitations and their complexities in the new deregulated operational environment. Development of the implementation software is an integral part of this research project. This software may be useful for both daily scheduling activities and short-term operational planning. A Lagrangian multipliers-based variant is used to solve the problem. Single line searches are used to update the multipliers, thus offering attractive execution times. This work also investigates the applicability of cooperative games to the problem of transmission cost allocation. Interest in game theory as a powerful tool to solve common property allocation problems has been renewed. A simple allocation framework is developed using capacity based costing rules. Different solution concepts are applied to solve small scale transmission pricing problems. Game models may render themselves useful in investigating "what if" scenarios.

  7. Golf-course and funnel energy landscapes: Protein folding concepts in martensites

    NASA Astrophysics Data System (ADS)

    Shankaraiah, N.

    2017-06-01

    We use protein folding energy landscape concepts such as golf course and funnel to study re-equilibration in athermal martensites under systematic temperature quench Monte Carlo simulations. On quenching below a transition temperature, the seeded high-symmetry parent-phase austenite that converts to the low-symmetry product-phase martensite, through autocatalytic twinning or elastic photocopying, has both rapid conversions and incubation delays in the temperature-time-transformation phase diagram. We find the rapid (incubation delays) conversions at low (high) temperatures arises from the presence of large (small) size of golf-course edge that has the funnel inside for negative energy states. In the incubating state, the strain structure factor enters into the Brillouin-zone golf course through searches for finite transitional pathways which close off at the transition temperature with Vogel-Fulcher divergences that are insensitive to Hamiltonian energy scales and log-normal distributions, as signatures of dominant entropy barriers. The crossing of the entropy barrier is identified through energy occupancy distributions, Monte Carlo acceptance fractions, heat emission, and internal work.

  8. Reverse logistics in the construction industry.

    PubMed

    Hosseini, M Reza; Rameezdeen, Raufdeen; Chileshe, Nicholas; Lehmann, Steffen

    2015-06-01

    Reverse logistics in construction refers to the movement of products and materials from salvaged buildings to a new construction site. While there is a plethora of studies looking at various aspects of the reverse logistics chain, there is no systematic review of literature on this important subject as applied to the construction industry. Therefore, the objective of this study is to integrate the fragmented body of knowledge on reverse logistics in construction, with the aim of promoting the concept among industry stakeholders and the wider construction community. Through a qualitative meta-analysis, the study synthesises the findings of previous studies and presents some actions needed by industry stakeholders to promote this concept within the real-life context. First, the trend of research and terminology related with reverse logistics is introduced. Second, it unearths the main advantages and barriers of reverse logistics in construction while providing some suggestions to harness the advantages and mitigate these barriers. Finally, it provides a future research direction based on the review. © The Author(s) 2015.

  9. Pathways to help-seeking in bulimia nervosa and binge eating problems: a concept mapping approach.

    PubMed

    Hepworth, Natasha; Paxton, Susan J

    2007-09-01

    To conduct an in-depth study, using concept mapping, of three factors related to help-seeking for bulimia nervosa and binge eating: problem recognition, barriers to help-seeking, and prompts to help-seeking. Semistructured interviews were conducted to elicit information about help-seeking with 63 women (18-62 years) with past or present bulimic behaviors. Using Leximancer software, factors identified as associated with problem recognition were Changes in Behavior, Interference with Life Roles, Comments about Changes and Psychological Problems. Salient barriers to help-seeking were Fear of Stigma, Low Mental Health Literacy/Perception of Need, Shame, Fear of Change and Cost. Prompts to help-seeking were increased Symptom Severity, Psychological Distress, Interference with Life Roles, Health Problems, and Desire to Get Better. Results highlighted the need for awareness campaigns to reduce both self and perceived stigma by others towards bulimic behaviors, and the need to enhance awareness of available interventions for people ready to engage in treatment, to increase help-seeking. (c) 2007 by Wiley Periodicals, Inc.

  10. [The historical perspective of the sentinel lymph node concept].

    PubMed

    Bekker, J; Meijer, S

    2008-01-05

    The sentinel lymph node procedure is currently standard care in the treatment of breast cancer. The introduction of this procedure in 1992 would not have been possible without the pioneering discoveries regarding lymph nodes and cancer. The Italian surgeon Gaspar Asellius (1581-1626) visualized the lymphatic vessels of a dog after it had been fed and shortly before dissection. At the end of the 17th century, the French anatomists Lauth and Sappey visualized the lymphatics by injecting deceased criminals with mercury. In 1858, the German pathologist Virchow (1821-1902) launched the theory that lymph nodes act as defensive barriers. He also made the first microscopical illustration ofa sentinel lymph node. Gould et al. and Cabaãs independently launched the precursors of the current modern sentinel lymph node concept in 1959 and 1977 respectively. Gould et al. were the first people to use the term "sentinel node'. Cabañas used lymphangiography for the visualisation of the sentinel lymph node. Controversies about the barrier function of the lymph nodes, the fear of skip metastasis and the difficulties of performing the Cabañas procedure, prevented a breakthrough of this concept. In 1992 Morton et al. rediscovered the valuable sentinel node biopsy concept and introduced blue dye for the investigation of patients with melanoma. The combination of lymphoscintigraphy, intra-operative gamma probe guidance and patent blue further increased the reliability of the sentinel lymph node biopsy procedure. Unnecessary lymph gland dissection procedures with considerable morbidity can be prevented by this procedure.

  11. Evaluating the Interdisciplinary Discoverability of Data

    NASA Astrophysics Data System (ADS)

    Gordon, S.; Habermann, T.

    2017-12-01

    Documentation needs are similar across communities. Communities tend to agree on many of the basic concepts necessary for discovery. Shared concepts such as a title or a description of the data exist in most metadata dialects. Many dialects have been designed and recommendations implemented to create metadata valuable for data discovery. These implementations can create barriers to discovering the right data. How can we ensure that the documentation we curate will be discoverable and understandable by researchers outside of our own disciplines and organizations? Since communities tend to use and understand many of the same documentation concepts, the barriers to interdisciplinary discovery are caused by the differences in the implementation. Thus tools and methods designed for the conceptual layer that evaluate records for documentation concepts, regardless of the dialect, can be effective in identifying opportunities for improvement and providing guidance. The Metadata Evaluation Web Service combined with a Jupyter Notebook interface allows a user to gather insight about a collection of records with respect to different communities' conceptual recommendations. It accomplishes this via data visualizations and provides links to implementation specific guidance on the ESIP Wiki for each recommendation applied to the collection. By utilizing these curation tools as part of an iterative process the data's impact can be increased by making it discoverable to a greater scientific and research community. Due to the conceptual focus of the methods and tools used, they can be utilized by any community or organization regardless of their documentation dialect or tools.

  12. Worlds apart? A scoping review addressing different stakeholder perspectives on barriers to family involvement in the care for persons with severe mental illness.

    PubMed

    Landeweer, Elleke; Molewijk, Bert; Hem, Marit Helene; Pedersen, Reidar

    2017-05-15

    Empirical evidence shows that family involvement (FI) can play a pivotal role in the coping and recovery of persons with severe mental illness (SMI). Nevertheless, various studies demonstrate that FI in mental healthcare services is often not (sufficiently) realized. In order to develop more insights, this scoping review gives an overview of how various stakeholders conceptualize, perceive and experience barriers to FI. Central questions are: 1) What are the main barriers to FI reported by the different key stakeholders (i.e. the persons with SMI, their families and the professionals, and 2) What are the differences and similarities between the various stakeholders' perspectives on these barriers. A systematic search into primary studies regarding FI was conducted in four databases: Medline/Pubmed, Cinahl, PsychInfo and Web of Knowledge with the use of a PICO scheme. Thematic analysis focused on stakeholder perspectives (i.e. which stakeholder group reports the barrier) and types of barriers (i.e. which types of barriers are addressed). Thirty three studies were included. The main barriers reported by the stakeholder groups reveal important similarities and differences between the stakeholder groups and were related to: 1) the person with SMI, 2) the family, 3) the professionals, 4) the organization of care and 5) the culture-paradigm. Our stakeholder approach elicits the different stakeholders' concepts, presuppositions and experiences of barriers to FI, and gives fundamental insights on how to deal with barriers to FI. The stakeholders differing interpretations and perceptions of the barriers related to FI is closely related to the inherent complexity involved in FI in itself. In order to deal better with these barriers, openly discussing and reflecting upon each other's normative understandings of barriers is needed. Differences in perceptions of barriers to FI can itself be a barrier. To deal with barriers to FI, a dialogical approach on how the different stakeholders perceive and value FI and its barriers is required. Methods such as moral case deliberation or systematic ethics reflections can be useful.

  13. Demonstration of fuel resistant to pellet-cladding interaction. Phase I. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rosenbaum, H.S.

    1979-03-01

    This program has as its ultimate objective the demonstration of an advanced fuel design that is resistant to the failure mechanism known as fuel pellet-cladding interaction (PCI). Two fuel concepts are being developed for possible demonstration within this program: (a) Cu-barrier fuel, and (b) Zr-liner fuel. These advanced fuels (known collectively as barrier fuels) have special fuel cladding designed to protect the Zircaloy cladding tube from the harmful effects of localized stress, and reactive fission products during reactor service. This is the final report for PHASE 1 of this program. Support tests have shown that the barrier fuel resists PCImore » far better than does the conventional Zircaloy-clad fuel. Power ramp tests thus far have shown good PCI resistance for Cu-barrier fuel at burnup > 12 MWd/kg-U and for Zr-liner fuel > 16 MWd/kg-U. The program calls for continued testing to still higher burnup levels in PHASE 2.« less

  14. Intestinal barrier dysfunction in cirrhosis: Current concepts in pathophysiology and clinical implications

    PubMed Central

    Tsiaoussis, Georgios I; Assimakopoulos, Stelios F; Tsamandas, Athanassios C; Triantos, Christos K; Thomopoulos, Konstantinos C

    2015-01-01

    The intestinal lumen is a host place for a wide range of microbiota and sets a unique interplay between local immune system, inflammatory cells and intestinal epithelium, forming a physical barrier against microbial invaders and toxins. Bacterial translocation is the migration of viable or nonviable microorganisms or their pathogen-associated molecular patterns, such as lipopolysaccharide, from the gut lumen to the mesenteric lymph nodes, systemic circulation and other normally sterile extraintestinal sites. A series of studies have shown that translocation of bacteria and their products across the intestinal barrier is a commonplace in patients with liver disease. The deterioration of intestinal barrier integrity and the consulting increased intestinal permeability in cirrhotic patients play a pivotal pathophysiological role in the development of severe complications as high rate of infections, spontaneous bacterial peritonitis, hepatic encephalopathy, hepatorenal syndrome, variceal bleeding, progression of liver injury and hepatocellular carcinoma. Nevertheless, the exact cellular and molecular mechanisms implicated in the phenomenon of microbial translocation in liver cirrhosis have not been fully elucidated yet. PMID:26301048

  15. Characterization and Modeling Analysis for Metal-Semiconductor-Metal GaAs Diodes with Pd/SiO2 Mixture Electrode

    PubMed Central

    Tan, Shih-Wei; Lai, Shih-Wen

    2012-01-01

    Characterization and modeling of metal-semiconductor-metal (MSM) GaAs diodes using to evaporate SiO2 and Pd simultaneously as a mixture electrode (called M-MSM diodes) compared with similar to evaporate Pd as the electrode (called Pd-MSM diodes) were reported. The barrier height (φ b) and the Richardson constant (A*) were carried out for the thermionic-emission process to describe well the current transport for Pd-MSM diodes in the consideration of the carrier over the metal-semiconductor barrier. In addition, in the consideration of the carrier over both the metal-semiconductor barrier and the insulator-semiconductor barrier simultaneously, thus the thermionic-emission process can be used to describe well the current transport for M-MSM diodes. Furthermore, in the higher applied voltage, the carrier recombination will be taken into discussion. Besides, a composite-current (CC) model is developed to evidence the concepts. Our calculated results are in good agreement with the experimental ones. PMID:23226352

  16. The influence of visual characteristics of barriers on railway noise perception.

    PubMed

    Maffei, Luigi; Masullo, Massimiliano; Aletta, Francesco; Di Gabriele, Maria

    2013-02-15

    Noise annoyance is considered as the main effect of noise, it is a complex and multifaceted psychological concept dealing with immediate behavioral and evaluative aspects. In the last decades the research has intensely investigated the correlation between noise exposure and noise annoyance, nevertheless recent studies confirm that non-auditory factors influence the noise perception of individuals. In particular audio-video interaction can play a fundamental role. Today Immersive Virtual Reality (IVR) systems allow building laboratory test providing realistic experiences of the surrounding environment to detect more accurate information about the reactions of the local population. Regarding the interventions for environmental noise control the barriers represent the main solution; however some aspects related to their visual characteristic have to be further investigated. This paper presented a case study, where a sample of residents living close to a railway line assessed noise-related aspects for several barriers with different visual characteristics in an IVR laboratory test. In particular, three main factors were analyzed: the barrier type concerning the visibility of the noise source through the screen, the visual aspect of the barrier concerning some aesthetic issues and the noise level at the receiver concerning the acoustic performance of the barrier and the magnitude of the sound source. The main results of the ANOVA analysis showed that for transparent barriers Perceived Loudness and Noise Annoyance were judged lower than for opaque barriers; this difference increased as noise level increased. Copyright © 2012. Published by Elsevier B.V.

  17. Health literacy: health professionals' understandings and their perceptions of barriers that Indigenous patients encounter.

    PubMed

    Lambert, Michelle; Luke, Joanne; Downey, Bernice; Crengle, Sue; Kelaher, Margaret; Reid, Susan; Smylie, Janet

    2014-11-29

    Despite the growing interest in health literacy, little research has been done around health professionals' knowledge of health literacy or understandings of the barriers to health literacy that patients face when navigating the health care system. Indigenous peoples in New Zealand (NZ), Canada and Australia experience numerous inequalities in health status and outcomes and international evidence reveals that Indigenous, minority, and socio-economically disadvantaged populations have greater literacy needs. To address concerns in Indigenous health literacy, a two-pronged approach inclusive of both education of health professionals, and structural reform reducing demands the system places on Indigenous patients, are important steps towards reducing these inequalities. Four Indigenous health care services were involved in the study. Interviews and one focus group were employed to explore the experiences of health professionals working with patients who had experienced cardiovascular disease (CVD) and were taking medications to prevent future events. A thematic analysis was completed and these insights were used in the development of an intervention that was tested as phase two of the study. Analysis of the data identified ten common themes. This paper concentrates on health professionals' understanding of health literacy and perceptions of barriers that their patients face when accessing healthcare. Health professionals' concepts of health literacy varied and were associated with their perceptions of the barriers that their patients face when attempting to build health literacy skills. These concepts ranged from definitions of health literacy that were focussed on patient deficit to broader definitions that focussed on both patients and the health system. All participants identified a combination of cultural, social and systemic barriers as impediments to their Indigenous patients improving their health literacy knowledge and practices. This study suggests that health professionals have a limited understanding of health literacy and of the consequences of low health literacy for their Indigenous patients. This lack of understanding combined with the perceived barriers to improving health literacy limit health professionals' ability to improve their Indigenous patients' health literacy skills and may limit patients' capacity to improve understanding of their illness and instructions on how to manage their health condition/s.

  18. Theory of Planned Behavior including self-stigma and perceived barriers explain help-seeking behavior for sexual problems in Iranian women suffering from epilepsy.

    PubMed

    Lin, Chung-Ying; Oveisi, Sonia; Burri, Andrea; Pakpour, Amir H

    2017-03-01

    To apply the Theory of Planned Behavior (TPB) and the two additional concepts self-stigma and perceived barriers to the help-seeking behavior for sexual problems in women with epilepsy. In this 18-month follow-up study, TPB elements, including attitude, subjective norm, perceived behavioral control, and behavioral intention along with self-stigma and perceived barriers in seeking help for sexual problems were assessed in n=818 women with epilepsy (94.0% aged ≤40years). The basic TPB model (model 1) and the TPB model additionally including self-stigma and perceived barriers (Model 2) were analyzed using structural equation modeling (SEM). Both SEM models showed satisfactory model fits. According to model, attitude, subjective norms, perceived behavioral control, and intention explained 63.1% of the variance in help-seeking behavior. Variance was slightly higher (64.5%) when including self-stigma and perceived barriers (model 2). In addition, the fit indices of the models were better highlighting the importance of self-stigma and perceived barriers in help-seeking behavior for sexual problems. Theory of Planned Behavior is useful in explaining help-seeking behavior for sexual problems in women with epilepsy. Self-stigma and perceived barriers are additional factors that should be considered in future interventions aiming to adopt TPB to improve help-seeking behavior for sexual problems. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. [Construction and validation of a short scale of perception of barriers for the physical activity in adolescents].

    PubMed

    Cabanas-Sánchez, Verónica; Tejero-González, Carlos M; Veiga, Oscar L

    2012-01-01

    One of the main problems of health in the first world is the increase of physical inactivity. In this respect, adolescence has been identified as a critic period with high decline of physical activity. Therefore, a relevant line of research is the understanding of this social phenomenon. The aim of this study was to design a scale to assess perceived barriers to physical activity on adolescents. A convenience sample of 160 Spanish adolescents (84 girls), between 12 and 18 years old, was recruited for this study. Firstly, there were designed 40 items whose pertinence was evaluated through content validation by experts. Later, the participants were divided in two randomized groups, and Exploratory Factor Analysis and Confirmatory Factor Analysis were performed to define a short scale of 12 items. Cronbach Alfa Coefficent was used to evaluate internal consistence of the instrument. The scale reports four dimensions: incompatibility barriers (2 items), self-concept barriers (4 items), amotivation barriers (4 items) and social barriers (2 items). The scale showed enough construct validity (χ2=60.78; d.f.=48; p=0.100; GFI=0.88; CFI=0.94; RMSEA=0.58) and high internal reliability (α=0.80). Moreover, the scale was able to explain 67% of the data variance. The Short Scale of Perceived Barriers to Physical Activity in Adolescents is a valid and reliable instrument.

  20. Lay public's understanding of equipoise and randomisation in randomised controlled trials.

    PubMed

    Robinson, E J; Kerr, C E P; Stevens, A J; Lilford, R J; Braunholtz, D A; Edwards, S J; Beck, S R; Rowley, M G

    2005-03-01

    To research the lay public's understanding of equipoise and randomisation in randomised controlled trials (RCTs) and to look at why information on this may not be not taken in or remembered, as well as the effects of providing information designed to overcome barriers. Investigations were informed by an update of systematic review on patients' understanding of consent information in clinical trials, and by relevant theory and evidence from experimental psychology. Nine investigations were conducted with nine participants. Access (return to education), leisure and vocational courses at Further Education Colleges in the Midlands, UK. Healthy adults with a wide range of educational backgrounds and ages. Participants read hypothetical scenarios and wrote brief answers to subsequent questions. Sub-samples of participants were interviewed individually to elaborate on their written answers. Participants' background assumptions concerning equipoise and randomisation were examined and ways of helping participants recognise the scientific benefits of randomisation were explored. Judgments on allocation methods; treatment preferences; the acceptability of random allocation; whether or not individual doctors could be completely unsure about the best treatment; whether or not doctors should reveal treatment preferences under conditions of collective equipoise; and how sure experts would be about the best treatment following random allocation vs doctor/patient choice. Assessments of understanding hypothetical trial information. Recent literature continues to report trial participants' failure to understand or remember information about randomisation and equipoise, despite the provision of clear and readable trial information leaflets. In current best practice, written trial information describes what will happen without offering accessible explanations. As a consequence, patients may create their own incorrect interpretations and consent or refusal may be inadequately informed. In six investigations, most participants identified which methods of allocation were random, but judged the random allocation methods to be unacceptable in a trial context; the mere description of a treatment as new was insufficient to engender a preference for it over a standard treatment; around half of the participants denied that a doctor could be completely unsure about the best treatment. A majority of participants judged it unacceptable for a doctor to suggest letting chance decide when uncertain of the best treatment, and, in the absence of a justification for random allocation, participants did not recognise scientific benefits of random allocation over normal treatment allocation methods. The pattern of results across three intervention studies suggests that merely supplementing written trial information with an explanation is unlikely to be helpful. However, when people manage to focus on the trial's aim of increasing knowledge (as opposed to making treatment decisions about individuals), and process an explanation actively, they may be helped to understand the scientific reasons for random allocation. This research was not carried out in real healthcare settings. However, participants who could correctly identify random allocation methods, yet judged random allocation unacceptable, doubted the possibility of individual equipoise and saw no scientific benefits of random allocation over doctor/patient choice, are unlikely to draw upon contrasting views if invited to enter a real clinical trial. This suggests that many potential trial participants may have difficulty understanding and remembering trial information that conforms to current best practice in its descriptions of randomisation and equipoise. Given the extent of the disparity between the assumptions underlying trial design and the assumptions held by the lay public, the solution is unlikely to be simple. Nevertheless, the results suggest that including an accessible explanation of the scientific benefits of randomisation may be beneficial provided potential participants are also enabled to reflect on the trial's aim of advancing knowledge, and to think actively about the information presented. Further areas for consideration include: the identification of effective combinations of written and oral information; helping participants to reflect on the aim of advancing knowledge; and an evidence-based approach to leaflet construction.

  1. Quantitative structure-activation barrier relationship modeling for Diels-Alder ligations utilizing quantum chemical structural descriptors.

    PubMed

    Nandi, Sisir; Monesi, Alessandro; Drgan, Viktor; Merzel, Franci; Novič, Marjana

    2013-10-30

    In the present study, we show the correlation of quantum chemical structural descriptors with the activation barriers of the Diels-Alder ligations. A set of 72 non-catalysed Diels-Alder reactions were subjected to quantitative structure-activation barrier relationship (QSABR) under the framework of theoretical quantum chemical descriptors calculated solely from the structures of diene and dienophile reactants. Experimental activation barrier data were obtained from literature. Descriptors were computed using Hartree-Fock theory using 6-31G(d) basis set as implemented in Gaussian 09 software. Variable selection and model development were carried out by stepwise multiple linear regression methodology. Predictive performance of the quantitative structure-activation barrier relationship (QSABR) model was assessed by training and test set concept and by calculating leave-one-out cross-validated Q2 and predictive R2 values. The QSABR model can explain and predict 86.5% and 80% of the variances, respectively, in the activation energy barrier training data. Alternatively, a neural network model based on back propagation of errors was developed to assess the nonlinearity of the sought correlations between theoretical descriptors and experimental reaction barriers. A reasonable predictability for the activation barrier of the test set reactions was obtained, which enabled an exploration and interpretation of the significant variables responsible for Diels-Alder interaction between dienes and dienophiles. Thus, studies in the direction of QSABR modelling that provide efficient and fast prediction of activation barriers of the Diels-Alder reactions turn out to be a meaningful alternative to transition state theory based computation.

  2. Shading responses of carbon allocation dynamics in mountain grassland

    NASA Astrophysics Data System (ADS)

    Bahn, M.; Lattanzi, F. A.; Brueggemann, N.; Siegwolf, R. T.; Richter, A.

    2012-12-01

    Carbon (C) allocation strongly influences plant and soil processes. Global environmental changes can alter source - sink relations of plants with potential implications for C allocation. Short-term C allocation dynamics in ecosystems and their responses to environmental changes are still poorly understood. To analyze effects of assimilate supply (i.e. C source strength) on ecosystem C allocation dynamics and the role of non-structural carbohydrates, canopy sections of a mountain meadow were pulse labeled with 13CO2 and subsequently shaded for a week or left unshaded (control). Tracer dynamics in above- and belowground sucrose and starch pools were analysed and coupled using compartmental modelling. The hypothesis was tested that shading affects tracer dynamics in non-structural carbohydrates and diminishes the transfer of recently assimilated C to roots and their storage pools. In unshaded plots up to 40% of assimilated C was routed through short-term storage in shoot starch and sucrose to buffer day / night cycles in photosynthesis. Shoot- and root sucrose and shoot starch were kinetically closely related pools. The tracer dynamics of the modelled root sucrose pool corresponded well with those in soil CO2 efflux. Root starch played no role in buffering day / night cycles and likely acted as a seasonal store. Shading strongly reduced sucrose and starch concentrations in shoots but not roots and resulted in a massive reduction of leaf respiration, while root respiration was much less diminished. Shading affected tracer dynamics in sucrose and starch of shoots: shoot starch rapidly lost tracer, while sucrose transiently increased its tracer content. Surprisingly, shading did not alter the dynamics of root carbohydrates. Even under severe C limitation after one week of shading, tracer C continued to be incorporated in root starch. Also the amount of 13C incorporated in phospholipid fatty acids of soil microbial communities was not reduced by shading, though its residence time followed a changed pattern, suggesting an influence of C source strength on the utilization and turnover of recent plant-derived C. These findings will be discussed in the broader context of plant and ecosystem carbon allocation, with particular reference to the concepts of 'source versus sink strength' and 'passive versus active C storage'.

  3. Game Theoretic Modeling of Water Resources Allocation Under Hydro-Climatic Uncertainty

    NASA Astrophysics Data System (ADS)

    Brown, C.; Lall, U.; Siegfried, T.

    2005-12-01

    Typical hydrologic and economic modeling approaches rely on assumptions of climate stationarity and economic conditions of ideal markets and rational decision-makers. In this study, we incorporate hydroclimatic variability with a game theoretic approach to simulate and evaluate common water allocation paradigms. Game Theory may be particularly appropriate for modeling water allocation decisions. First, a game theoretic approach allows economic analysis in situations where price theory doesn't apply, which is typically the case in water resources where markets are thin, players are few, and rules of exchange are highly constrained by legal or cultural traditions. Previous studies confirm that game theory is applicable to water resources decision problems, yet applications and modeling based on these principles is only rarely observed in the literature. Second, there are numerous existing theoretical and empirical studies of specific games and human behavior that may be applied in the development of predictive water allocation models. With this framework, one can evaluate alternative orderings and rules regarding the fraction of available water that one is allowed to appropriate. Specific attributes of the players involved in water resources management complicate the determination of solutions to game theory models. While an analytical approach will be useful for providing general insights, the variety of preference structures of individual players in a realistic water scenario will likely require a simulation approach. We propose a simulation approach incorporating the rationality, self-interest and equilibrium concepts of game theory with an agent-based modeling framework that allows the distinct properties of each player to be expressed and allows the performance of the system to manifest the integrative effect of these factors. Underlying this framework, we apply a realistic representation of spatio-temporal hydrologic variability and incorporate the impact of decision-making a priori to hydrologic realizations and those made a posteriori on alternative allocation mechanisms. Outcomes are evaluated in terms of water productivity, net social benefit and equity. The performance of hydro-climate prediction modeling in each allocation mechanism will be assessed. Finally, year-to-year system performance and feedback pathways are explored. In this way, the system can be adaptively managed toward equitable and efficient water use.

  4. A conceptual model of incarcerated adolescent fatherhood: adolescent identity development and the concept of intersectionality.

    PubMed

    Shade, Kate; Kools, Susan; Weiss, Sandra J; Pinderhughes, Howard

    2011-05-01

    Little is known about teen fathers though they are found to be disproportionately represented among incarcerated youth. SOURCE USED: This article is developed from a qualitative pilot study of adolescent fathers in the justice system. The authors theorize about teen fathers and the process by which they accept, reject, or are "barriered" from a father identity and role. Adolescence as a developmental period during which an identity is forming is viewed in concert with the concept of hegemonic masculinity and the concept of intersectionality. Risk factors in childhood and adolescence complete the conceptual model through which incarcerated adolescent fathers can be examined. © 2011 Wiley Periodicals, Inc.

  5. From concept to reality in implementing the Knowledge Triangle

    NASA Astrophysics Data System (ADS)

    Sjoer, Ellen; Nørgaard, Bente; Goossens, Marc

    2016-05-01

    The concept of Knowledge Triangle (KT) links together research, education and innovation and replaces the traditional 'one way' flow of knowledge, essentially from research to education, by a 'both ways' circular motion between all the corners of a triangle that, besides research and education, also includes innovation, the 'poor relation' of many universities. What are the main issues - barriers and drivers - and what could be done in order to make the concept of KT a strong reality in engineering education? In this paper, the authors intend to bring some answers by analysing three cases coming from actors operating at the three corners of the KT: students, academic staff and engineers in industry.

  6. Evolutionary public health: introducing the concept.

    PubMed

    Wells, Jonathan C K; Nesse, Randolph M; Sear, Rebecca; Johnstone, Rufus A; Stearns, Stephen C

    2017-07-29

    The emerging discipline of evolutionary medicine is breaking new ground in understanding why people become ill. However, the value of evolutionary analyses of human physiology and behaviour is only beginning to be recognised in the field of public health. Core principles come from life history theory, which analyses the allocation of finite amounts of energy between four competing functions-maintenance, growth, reproduction, and defence. A central tenet of evolutionary theory is that organisms are selected to allocate energy and time to maximise reproductive success, rather than health or longevity. Ecological interactions that influence mortality risk, nutrient availability, and pathogen burden shape energy allocation strategies throughout the life course, thereby affecting diverse health outcomes. Public health interventions could improve their own effectiveness by incorporating an evolutionary perspective. In particular, evolutionary approaches offer new opportunities to address the complex challenges of global health, in which populations are differentially exposed to the metabolic consequences of poverty, high fertility, infectious diseases, and rapid changes in nutrition and lifestyle. The effect of specific interventions is predicted to depend on broader factors shaping life expectancy. Among the important tools in this approach are mathematical models, which can explore probable benefits and limitations of interventions in silico, before their implementation in human populations. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Transitioning Resolution Responsibility between the Controller and Automation Team in Simulated NextGen Separation Assurance

    NASA Technical Reports Server (NTRS)

    Cabrall, C.; Gomez, A.; Homola, J.; Hunt, S..; Martin, L.; Merccer, J.; Prevott, T.

    2013-01-01

    As part of an ongoing research effort on separation assurance and functional allocation in NextGen, a controller- in-the-loop study with ground-based automation was conducted at NASA Ames' Airspace Operations Laboratory in August 2012 to investigate the potential impact of introducing self-separating aircraft in progressively advanced NextGen timeframes. From this larger study, the current exploratory analysis of controller-automation interaction styles focuses on the last and most far-term time frame. Measurements were recorded that firstly verified the continued operational validity of this iteration of the ground-based functional allocation automation concept in forecast traffic densities up to 2x that of current day high altitude en-route sectors. Additionally, with greater levels of fully automated conflict detection and resolution as well as the introduction of intervention functionality, objective and subjective analyses showed a range of passive to active controller- automation interaction styles between the participants. Not only did the controllers work with the automation to meet their safety and capacity goals in the simulated future NextGen timeframe, they did so in different ways and with different attitudes of trust/use of the automation. Taken as a whole, the results showed that the prototyped controller-automation functional allocation framework was very flexible and successful overall.

  8. Tracking historical increases in nitrogen-driven crop production possibilities

    NASA Astrophysics Data System (ADS)

    Mueller, N. D.; Lassaletta, L.; Billen, G.; Garnier, J.; Gerber, J. S.

    2015-12-01

    The environmental costs of nitrogen use have prompted a focus on improving the efficiency of nitrogen use in the global food system, the primary source of nitrogen pollution. Typical approaches to improving agricultural nitrogen use efficiency include more targeted field-level use (timing, placement, and rate) and modification of the crop mix. However, global efficiency gains can also be achieved by improving the spatial allocation of nitrogen between regions or countries, due to consistent diminishing returns at high nitrogen use. This concept is examined by constructing a tradeoff frontier (or production possibilities frontier) describing global crop protein yield as a function of applied nitrogen from all sources, given optimal spatial allocation. Yearly variation in country-level input-output nitrogen budgets are utilized to parameterize country-specific hyperbolic yield-response models. Response functions are further characterized for three ~15-year eras beginning in 1961, and series of calculations uses these curves to simulate optimal spatial allocation in each era and determine the frontier. The analyses reveal that excess nitrogen (in recent years) could be reduced by ~40% given optimal spatial allocation. Over time, we find that gains in yield potential and in-country nitrogen use efficiency have led to increases in the global nitrogen production possibilities frontier. However, this promising shift has been accompanied by an actual spatial distribution of nitrogen use that has become less optimal, in an absolute sense, relative to the frontier. We conclude that examination of global production possibilities is a promising approach to understanding production constraints and efficiency opportunities in the global food system.

  9. Concept of Operations for Integrating Commercial Supersonic Transport Aircraft into the National Airspace System

    NASA Technical Reports Server (NTRS)

    Underwood, Matthew C.

    2017-01-01

    Several businesses and government agencies, including the National Aeronautics and Space Administration are currently working on solving key technological barriers that must be overcome in order to realize the vision of low-boom supersonic flights conducted over land. However, once these challenges are met, the manner in which this class of aircraft is integrated in the National Airspace System may become a potential constraint due to the significant environmental, efficiency, and economic repercussions that their integration may cause. This document was developed to create a path for research and development that exposes the benefits and barriers of seamlessly integrating a class of CSTs into the NAS, while also serving as a Concept of Operations (ConOps) which posits a mid- to far-term solution (2025-2035) concept for best integrating CST into the NAS. Background research regarding historic supersonic operations in the National Airspace System, assumptions about design aspects and equipage of commercial supersonic transport (CST) aircraft, assumptions concerning the operational environment are described in this document. Results of a simulation experiment to investigate the interactions between CST aircraft and modern-day air traffic are disseminated and are used to generate scenarios for CST operations. Finally, technology needs to realize these operational scenarios are discussed.

  10. Harmonizing Operas Voices. an Investigation of Different Perspectives on the Ecosystem Services Concept and Implications for Research and Practice.

    NASA Astrophysics Data System (ADS)

    Hermelingmeier, V.

    2014-12-01

    Over the past 150 years, humans have altered the planet at a rapid pace. In this new era, the Anthropocene, environmental degradation has come to a state where sustainable ecosystem management has developed into an urgent quest for humans to maintain their own life-support system. The ecosystem services (ES) concept, initially introduced as potential facilitator to manage this quest, has been criticized for its vagueness to pose a barrier to the concept's application in practice. Therefore, the focus of this paper is on this vagueness as potential barrier to successful collaboration in the research community (interdisicplinarity) as a precondition to the concept's application for sustainable ecosystem management (transdisicplinarity). Focusing on the European research project Operational Potential for Ecosystem Research Applications (OPERAs), the objective is to serve the research community with the identification of differences in conceptual perspectives on ES (differentiation), in order to recommend an effective way of handling these differences (clarification) as a basis for interdisciplinary integration (synthesis). With an emphasis on differentiation and clarification, the research process concentrates on the derivation of a typology of perspectives from the literature (RQ 1), on the basis of which perspectives in OPERAs are assessed with the help of Q methodology (RQ 2) in order to derive implications for how to handle the concept in the future (RQ 3). The main findings suggest clear differences between three foundational perspectives but a more nuanced variety of viewpoints in OPERAs that can be summarized under five main perspectives. Whereas the notion of interdisciplinarity has often steered the focus towards disciplinary worldviews as the cause for different perspectives, the results point to the insight that perspectives on the ES concept are influenced by a more complex interplay of paradigmatic assumptions. Therefore, clarification is suggested to encompass more than the standardization of discipline-induced worldviews and to require open dialogue on underlying values and ethical stances. In synthesis, the question is not only how to use the ES concept effectively but also to what extent the concept can suffice sustainable ecosystem management in the long-term.

  11. Stakeholders' views on the routine use of n-of-1 trials to improve clinical care and to make resource allocation decisions for drug use.

    PubMed

    Nikles, Jane; Mitchell, Geoffrey K; Clavarino, Alexandra; Yelland, Michael J; Del Mar, Christopher B

    2010-03-01

    N-of-1 trials are empirical formal tests using a within-patient randomised, double-blind, cross-over comparison of drug and placebo (or another drug), which we adapted to study individual patients' responses as a clinical tool to guide clinical management. We administered semi-structured interviews to gauge stakeholder perspectives on the possibility of using routine n-of-1 trials for this purpose. Stakeholders included government and non-government health care sector, and patient, clinician and consumer, organisations. Stakeholders supported more widespread implementation of n-of-1 trials, in a targeted fashion, with some caveats. Barriers to their widespread implementation included constraints on doctors' time, doctors' acceptance, drug company acceptance, patient willingness, and cost. Strategies for overcoming barriers included conditional Pharmaceutical Benefits Scheme listing if cost-effective. There was little consensus on which model of n-of-1 trial implementation would be most effective. We discuss different approaches to addressing the several concerns raised to enable widespread introduction of n-of-1 trials into routine clinical practice as a decision tool.

  12. Stakeholder's perspective: Sustainability of a community health worker program in Afghanistan.

    PubMed

    Najafizada, Said Ahmad Maisam; Labonté, Ronald; Bourgeault, Ivy Lynn

    2017-02-01

    The objectives of this study were two-fold: 1) to examine how different stakeholders define sustainability, and 2) to identify barriers to and facilitators of the sustainability of the Afghan CHW program. We interviewed 63 individual key informants, and conducted 11 focus groups [35 people] with policymakers, health managers, community health workers, and community members across Afghanistan. The participants were purposefully selected to provide a wide range of perspectives. Different stakeholders define sustainability differently. Policymakers emphasize financial resources; health managers, organizational operations; and community-level stakeholders, routine frontline activities. The facilitators they identify include integration into the health system, community support, and capable human resources. Barriers they noted include lack of financial resources, poor program design and implementation, and poor quality of services. Measures to ensure sustainability could be national revenue allocation, health-specific taxation, and community financing. Sustainability is complicated and has multiple facets. The plurality of understanding of sustainability among stakeholders should be addressed explicitly in the program design. To ensure sustainability, there is a need for a coordinated effort amongst all stakeholders. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Water use benefit index as a tool for community-based monitoring of water related trends in the Great Barrier Reef region

    NASA Astrophysics Data System (ADS)

    Smajgl, A.; Larson, S.; Hug, B.; De Freitas, D. M.

    2010-12-01

    SummaryThis paper presents a tool for documenting and monitoring water use benefits in the Great Barrier Reef catchments that allows temporal and spatial comparison along the region. Water, water use benefits and water allocations are currently receiving much attention from Australian policy makers and conservation practitioners. Because of the inherent complexity and variability in water quality, it is essential that scientific information is presented in a meaningful way to policy makers, managers and ultimately, to the general public who have to live with the consequences of the decisions. We developed an inexpensively populated and easily understandable water use benefit index as a tool for community-based monitoring of water related trends in the Great Barrier Reef region. The index is developed based on a comparative list of selected water-related indices integrating attributes across physico-chemical, economic, social, and ecological domains currently used in the assessment of water quality, water quantity and water use benefits in Australia. Our findings indicate that the proposed index allows the identification of water performance indicators by temporal and spatial comparisons. Benefits for decision makers and conservation practitioners include a flexible way of prioritization towards the domain with highest concern. The broader community benefits from a comprehensive and user-friendly tool, communicating changes in water quality trends more effectively.

  14. The roles, barriers and experiences of rehabilitation therapists in disaster relief: post-earthquake Haiti 2010.

    PubMed

    Klappa, Susan; Audette, Jennifer; Do, Sandy

    2014-01-01

    This article describes the roles and experiences of rehabilitation therapists involved in disaster relief work (DRW) in Haiti after the 2010 earthquake. The results of a pilot study and phenomenological study are presented. A phenomenological study of rehabilitation providers' experiences in post-disaster relief care is presented along with preliminary pilot study results. The phenomenological study explored the experiences of therapists from a lived experience perspective through the roles they played in DRW. Participants provided disaster relief through direct patient care, adaptive equipment sourcing and allocation, education and training, community outreach and logistic or administrative duties. Barriers and challenges included: (1) emotions: ups and downs; (2) challenges: working at the edge of practice; (3) education: key to success and sustainability; (4) lessons learned: social responsibility is why we go; and (5) difficulty coming home: no one understands. Therapists play a key role in disaster relief situations. Data presented should encourage organizations to include therapists from early planning to implementation of relief services. Further studies are needed to evaluate the impact of rehabilitation interventions in disaster settings. Understanding the roles and experiences of therapists in disaster relief setting is important Certain barriers to providing care in post-disaster settings exist Those participating in disaster response should be well prepared and aware of that they might be asked to do.

  15. Glutamate-Mediated Blood-Brain Barrier Opening: Implications for Neuroprotection and Drug Delivery.

    PubMed

    Vazana, Udi; Veksler, Ronel; Pell, Gaby S; Prager, Ofer; Fassler, Michael; Chassidim, Yoash; Roth, Yiftach; Shahar, Hamutal; Zangen, Abraham; Raccah, Ruggero; Onesti, Emanuela; Ceccanti, Marco; Colonnese, Claudio; Santoro, Antonio; Salvati, Maurizio; D'Elia, Alessandro; Nucciarelli, Valter; Inghilleri, Maurizio; Friedman, Alon

    2016-07-20

    The blood-brain barrier is a highly selective anatomical and functional interface allowing a unique environment for neuro-glia networks. Blood-brain barrier dysfunction is common in most brain disorders and is associated with disease course and delayed complications. However, the mechanisms underlying blood-brain barrier opening are poorly understood. Here we demonstrate the role of the neurotransmitter glutamate in modulating early barrier permeability in vivo Using intravital microscopy, we show that recurrent seizures and the associated excessive glutamate release lead to increased vascular permeability in the rat cerebral cortex, through activation of NMDA receptors. NMDA receptor antagonists reduce barrier permeability in the peri-ischemic brain, whereas neuronal activation using high-intensity magnetic stimulation increases barrier permeability and facilitates drug delivery. Finally, we conducted a double-blind clinical trial in patients with malignant glial tumors, using contrast-enhanced magnetic resonance imaging to quantitatively assess blood-brain barrier permeability. We demonstrate the safety of stimulation that efficiently increased blood-brain barrier permeability in 10 of 15 patients with malignant glial tumors. We suggest a novel mechanism for the bidirectional modulation of brain vascular permeability toward increased drug delivery and prevention of delayed complications in brain disorders. In this study, we reveal a new mechanism that governs blood-brain barrier (BBB) function in the rat cerebral cortex, and, by using the discovered mechanism, we demonstrate bidirectional control over brain endothelial permeability. Obviously, the clinical potential of manipulating BBB permeability for neuroprotection and drug delivery is immense, as we show in preclinical and proof-of-concept clinical studies. This study addresses an unmet need to induce transient BBB opening for drug delivery in patients with malignant brain tumors and effectively facilitate BBB closure in neurological disorders. Copyright © 2016 the authors 0270-6474/16/367727-13$15.00/0.

  16. Perceptions of Approved Clinical Instructors: Barriers in the Implementation of Evidence-Based Practice

    PubMed Central

    Hankemeier, Dorice A.; Van Lunen, Bonnie L.

    2013-01-01

    Context: As evidence-based practice (EBP) becomes prevalent in athletic training education, the barriers that Approved Clinical Instructors (ACIs) experience in implementing it with students need to be understood. Objective: To investigate barriers ACIs face when implementing EBP concepts in clinical practice and in teaching EBP to professional athletic training students and to investigate the educational emphases to improve the barriers. Design: Qualitative study. Setting: Telephone interviews. Patients or Other Participants: Sixteen ACIs (11 men, 5 women; experience as an athletic trainer = 10 ± 4.7 years, experience as an ACI = 6.81 ± 3.9 years) were interviewed. Data Collection and Analysis: We interviewed each participant by telephone. Interview data were analyzed and coded for common themes and subthemes regarding barriers and educational emphases. Themes were triangulated through multiple-analyst triangulation and interpretive verification. Results: Barriers to EBP incorporation and educational emphasis placed on EBP were the main themes reported. Resources, personnel, and student characteristics were subthemes identified as barriers. Resource barriers included time, equipment, access to current literature, and knowledge. Coworkers, clinicians, and coaches who were unwilling to accept evidence regarding advancements in treatment were identified as personnel barriers. Programmatic improvement and communication improvement were subthemes of the educational emphasis placed on EBP theme. The ACIs reported the need for better integration between the clinical setting and the classroom and expressed the need for EBP to be integrated throughout the athletic training education program. Conclusions: Integration of the classroom and clinical experience is important in advancing ACIs' use of EBP with their students. Collaborative efforts within the clinical and academic program could help address the barriers ACIs face when implementing EBP. This collaboration could positively affect the ability of ACIs to implement EBP within their clinical practices. PMID:23675798

  17. Glutamate-Mediated Blood–Brain Barrier Opening: Implications for Neuroprotection and Drug Delivery

    PubMed Central

    Vazana, Udi; Veksler, Ronel; Pell, Gaby S.; Prager, Ofer; Fassler, Michael; Chassidim, Yoash; Roth, Yiftach; Shahar, Hamutal; Zangen, Abraham; Raccah, Ruggero; Onesti, Emanuela; Ceccanti, Marco; Colonnese, Claudio; Santoro, Antonio; Salvati, Maurizio; D'Elia, Alessandro; Nucciarelli, Valter; Inghilleri, Maurizio

    2016-01-01

    The blood–brain barrier is a highly selective anatomical and functional interface allowing a unique environment for neuro-glia networks. Blood–brain barrier dysfunction is common in most brain disorders and is associated with disease course and delayed complications. However, the mechanisms underlying blood–brain barrier opening are poorly understood. Here we demonstrate the role of the neurotransmitter glutamate in modulating early barrier permeability in vivo. Using intravital microscopy, we show that recurrent seizures and the associated excessive glutamate release lead to increased vascular permeability in the rat cerebral cortex, through activation of NMDA receptors. NMDA receptor antagonists reduce barrier permeability in the peri-ischemic brain, whereas neuronal activation using high-intensity magnetic stimulation increases barrier permeability and facilitates drug delivery. Finally, we conducted a double-blind clinical trial in patients with malignant glial tumors, using contrast-enhanced magnetic resonance imaging to quantitatively assess blood–brain barrier permeability. We demonstrate the safety of stimulation that efficiently increased blood–brain barrier permeability in 10 of 15 patients with malignant glial tumors. We suggest a novel mechanism for the bidirectional modulation of brain vascular permeability toward increased drug delivery and prevention of delayed complications in brain disorders. SIGNIFICANCE STATEMENT In this study, we reveal a new mechanism that governs blood–brain barrier (BBB) function in the rat cerebral cortex, and, by using the discovered mechanism, we demonstrate bidirectional control over brain endothelial permeability. Obviously, the clinical potential of manipulating BBB permeability for neuroprotection and drug delivery is immense, as we show in preclinical and proof-of-concept clinical studies. This study addresses an unmet need to induce transient BBB opening for drug delivery in patients with malignant brain tumors and effectively facilitate BBB closure in neurological disorders. PMID:27445149

  18. Beyond Your Beliefs: Quantum Leaps toward Quality Schools.

    ERIC Educational Resources Information Center

    Rhodes, Lewis A.

    1990-01-01

    W. Edwards Deming's concepts offer an integrated approach to quality schooling. Three barriers must be overcome: fear of industrial models, poor knowledge of workers and work processes, and unquestioned beliefs. Instead, educators must develop community understanding and commitment, establish business-education partnerships, and manage schools as…

  19. Adsorption And Simultaneous Dechlorination Of PCBs On GAC/Fe/Pd: Mechanistic Aspects And Reactive Capping Barrier Concept

    EPA Science Inventory

    There are many concerns and challenges in current remediation strategies for sediments contaminated with polychlorinated biphenyls (PCBs). Our efforts have been geared toward the development of granular activated carbon (GAC) impregnated with reactive iron/palladium (Fe/Pd) bime...

  20. Managing Problem-Based Learning in Large Lecture Sections

    ERIC Educational Resources Information Center

    Bledsoe, Karen E.

    2011-01-01

    Problem-based learning can enhance reasoning and concept development among undergraduate college students by presenting content within authentic contexts. However, large lecture sections present problems and barriers to implementing PBL. This article discusses approaches used by the author to infuse PBL into large biology lecture sections, and…

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