Comparative Analysis of the Effects of Severe Plastic Deformation and Thermomechanical Training on the Functional Stability of Ti50.5Ni24.5Pd25 High-Temperature Shape Memory Alloy

NASA Technical Reports Server (NTRS)

Atli, K. C.; Karaman, I.; Noebe, R. D.; Maier, H. J.

2010-01-01

We compare the effectiveness of a conventional thermomechanical training procedure and severe plastic deformation via equal channel angular extrusion to achieve improved functional stability in a Ti50.5Ni24.5Pd25 high-temperature shape memory alloy. Thermomechanical testing indicates that both methods result in enhanced shape memory characteristics, such as reduced irrecoverable strain and thermal hysteresis. The mechanisms responsible for the improvements are discussed in light of microstructural findings from transmission electron microscopy.

"No DH, No Interview"

ERIC Educational Resources Information Center

Pannapacker, William

2012-01-01

In this article, the author discusses digital humanities (DH) and what future it holds for graduate students who are riding the digital-humanities bandwagon. He spoke with several graduate students about their interest in the field: how they got into it and began their first projects. Laura Mandell, director of the Initiative for Digital…

A behavior-oriented dynamic model for sandbar migration and 2DH evolution

USGS Publications Warehouse

Splinter, K.D.; Holman, R.A.; Plant, N.G.

2011-01-01

A nonlinear model is developed to study the time-dependent relationship between the alongshore variability of a sandbar, a(t), and alongshore-averaged sandbar position, xc(t). Sediment transport equations are derived from energetics-based formulations. A link between this continuous physical representation and a parametric form describing the migration of sandbars of constant shape is established through a simple transformation of variables. The model is driven by offshore wave conditions. The parametric equations are dynamically coupled such that changes in one term (i.e., xc) drive changes in the other (i.e., a(t)). The model is tested on 566 days of data from Palm Beach, New South Wales, Australia. Using weighted nonlinear least squares to estimate best fit model coefficients, the model explained 49% and 41% of the variance in measured xc and a(t), respectively. Comparisons against a 1-D horizontal (1DH) version of the model showed significant improvements when the 2DH terms were included (1DH and 2DH Brier skill scores were -0.12 and 0.42, respectively). Onshore bar migration was not predicted in the 1DH model, while the 2DH model correctly predicted onshore migration in the presence of 2DH morphology and allowed the bar to remain closer to shore for a given amount of breaking, providing an important hysteresis to the system. The model is consistent with observations that active bar migration occurs under breaking waves with onshore migration occurring at timescales of days to weeks and increasing 2DH morphology, while offshore migration occurs rapidly under high waves and coincides with a reduction in 2DH morphology. Copyright ?? 2011 by the American Geophysical Union.

The D/H ratio in Saturn's atmosphere from Voyager IRIS spectra

NASA Technical Reports Server (NTRS)

Courtin, R.; Gautier, D.; Marten, A.; Bezard, B.; Hanel, R.

1985-01-01

A selection of 1656 spectra recorded between 180 and 2300 mm in the 20 to 40 N latitude range by the Voyager interferometer IRIS were analyzed. The CH3D/H2 and CH4/H2 ratios are determined from a best fit of the radiances measured in the nu6 and nu4 fundamental bands, respectively centered at 1161 and 1304 mm. Results are CH3D/H2 = 3.9 + or - 2.5 times 10 to the minus 7th power and CH4/H2 = 4.5 + 2.4, -1.9 x 0.001. The uncertainty includes random errors due to instrumental noise and possible systematic errors in the assumed temperature profile and spectroscopic parameters. The D/H isotopic ratio is determined from abundance ratios from the expression D/H = 1/4f (CH3D/H2)/(CH4/H2) where f accounts for equilibrium deuterium fractionation between the molecular hydrogen and methane phases. Beer and Taylor (1973, 1978) estimated f = 1.37 + or - 0.07 for Jupiter assuming a wide range of convective velocities and neglecting catalytic effects from dust particles. The same value was adopted for Saturn and yields D/H = 1.6 +1.3, -1.2 times 10 to the minus 5th power.

2,4,5-Trichlorophenoxyacetic acid (2,4,5-T)

Integrated Risk Information System (IRIS)

2,4,5 - Trichlorophenoxyacetic acid ( 2,4,5 - T ) ; CASRN 93 - 76 - 5 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard

An Upper Limit on the Mass of the Circumplanetary Disk for DH Tau b

NASA Astrophysics Data System (ADS)

Wolff, Schuyler G.; Ménard, François; Caceres, Claudio; Lefèvre, Charlene; Bonnefoy, Mickael; Cánovas, Héctor; Maret, Sébastien; Pinte, Christophe; Schreiber, Matthias R.; van der Plas, Gerrit

2017-07-01

DH Tau is a young (˜1 Myr) classical T Tauri star. It is one of the few young PMS stars known to be associated with a planetary mass companion, DH Tau b, orbiting at large separation and detected by direct imaging. DH Tau b is thought to be accreting based on copious {{H}}α emission and exhibits variable Paschen Beta emission. NOEMA observations at 230 GHz allow us to place constraints on the disk dust mass for both DH Tau b and the primary in a regime where the disks will appear optically thin. We estimate a disk dust mass for the primary, DH Tau A of 17.2+/- 1.7 {M}\\oplus , which gives a disk to star mass ratio of 0.014 (assuming the usual gas to dust mass ratio of 100 in the disk). We find a conservative disk dust mass upper limit of 0.42 M ⊕ for DH Tau b, assuming that the disk temperature is dominated by irradiation from DH Tau b itself. Given the environment of the circumplanetary disk, variable illumination from the primary or the equilibrium temperature of the surrounding cloud would lead to even lower disk mass estimates. A MCFOST radiative transfer model, including heating of the circumplanetary disk by DH Tau b and DH Tau A, suggests that a mass-averaged disk temperature of 22 K is more realistic, resulting in a dust disk mass upper limit of 0.09 M ⊕ for DH Tau b. We place DH Tau b in context with similar objects and discuss the consequences for planet formation models. This work is based on observations carried out under project D15AC with the IRAM NOEMA Interferometer. IRAM is supported by INSU/CNRS (France), MPG (Germany), and IGN (Spain).

Integration of Decentralized Thermal Storages Within District Heating (DH) Networks

NASA Astrophysics Data System (ADS)

Schuchardt, Georg K.

2016-12-01

Thermal Storages and Thermal Accumulators are an important component within District Heating (DH) systems, adding flexibility and offering additional business opportunities for these systems. Furthermore, these components have a major impact on the energy and exergy efficiency as well as the heat losses of the heat distribution system. Especially the integration of Thermal Storages within ill-conditioned parts of the overall DH system enhances the efficiency of the heat distribution. Regarding an illustrative and simplified example for a DH system, the interactions of different heat storage concepts (centralized and decentralized) and the heat losses, energy and exergy efficiencies will be examined by considering the thermal state of the heat distribution network.

The D/H ratio in water from Halley

NASA Technical Reports Server (NTRS)

Eberhardt, P.; Dolder, U.; Schulte, W.; Krankowsky, D.; Laemmerzahl, P.; Hoffman, J. H.; Hodges, R. R.; Berthelier, J. J.; Illiano, J. M.

1986-01-01

The neutral gas mass spectrometer on Giotto made neutral and ion composition measurements with a high mass resolution. Evaluation of the ion data within the contact surface gives a D/H ratio in water from Halley between 0.00006 and 0.00048. While this ratio is definitely not compatible with the D/H in molecular hydrogen of the protosolar nebula or the Jovian and Saturnian atmospheres, it is in the range observed for hydrogen in solar system objects which acquired their hydrogen as part of volatile molecules, e.g., as ices.

17 CFR 245.100 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

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17 CFR 245.100 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

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17 CFR 245.100 - Definitions.

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2013-04-01

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8 CFR 245a.6 - Treatment of denied application under part 245a, Subpart B.

Code of Federal Regulations, 2012 CFR

2012-01-01

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8 CFR 245a.6 - Treatment of denied application under part 245a, Subpart B.

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2013-01-01

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8 CFR 245a.6 - Treatment of denied application under part 245a, Subpart B.

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2014-01-01

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8 CFR 245a.6 - Treatment of denied application under part 245a, Subpart B.

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2011-01-01

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8 CFR 245a.6 - Treatment of denied application under part 245a, Subpart B.

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2010-01-01

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48 CFR 245.609 - Donations.

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2010-10-01

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32 CFR 245.33 - Approval.

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2010-07-01

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9 CFR 354.245 - Vermin.

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2010-01-01

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7 CFR 65.245 - Secretary.

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2010-01-01

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7 CFR 65.245 - Secretary.

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2013-01-01

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7 CFR 65.245 - Secretary.

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2011-01-01

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7 CFR 65.245 - Secretary.

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2014-01-01

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7 CFR 65.245 - Secretary.

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2012-01-01

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33 CFR 245.15 - Delegation.

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2011-07-01

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33 CFR 245.15 - Delegation.

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Nebular dead zone effects on the D/H ratio in chondrites and comets

NASA Astrophysics Data System (ADS)

Ali-Dib, Mohamad; Martin, R. G.; Petit, J.-M.; Mousis, O.; Vernazza, P.; Lunine, J. I.

2015-11-01

Comets and chondrites show non-monotonic behaviour of their Deuterium to Hydrogen (D/H) ratio as a function of their formation location from the Sun. This is difficult to explain with a classical protoplanetary disk model that has a decreasing temperature structure with radius from the Sun.We want to understand if a protoplanetary disc with a dead zone, a region of zero or low turbulence, can explain the measured D/H values in comets and chondrites. We use time snapshots of a vertically layered disk model with turbulent surface layers and a dead zone at the midplane. The disc has a non-monotonic temperature structure due to increased heating from self-gravity in the outer parts of the dead zone. We couple this to a D/H ratio evolution model in order to quantify the effect of such thermal profiles on D/H enrichment in the nebula.We find that the local temperature peak in the disk can explain the diversity in the D/H ratios of different chondritic families. This disk temperature profile leads to a non-monotonic D/H enrichment evolution, allowing these families to acquire their different D/H values while forming in close proximity. The formation order we infer for these families is compatible with that inferred from their water abundances. However, we find that even for very young disks, the thermal profile reversal is too close to the Sun to be relevant for comets.[1] Ali-Dib, M., Martin, R. G., Petit, J.-M., Mousis, O., Vernazza, P., and Lunine, J. I. (2015, in press A&A). arXiv:1508.00263.

17 CFR 245.100 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... BLACKOUT TRADING RESTRICTION § 245.100 Definitions. As used in Regulation BTR (§§ 245.100 through 245.104... blackout period: (1) With respect to the equity securities of any issuer (other than a foreign private... temporary suspension exceeds 15% of the total number of employees of the issuer and its consolidated...

8 CFR 245.6 - Interview.

Code of Federal Regulations, 2010 CFR

2010-01-01

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Comments on D/H ratios in chondritic organic matter

NASA Astrophysics Data System (ADS)

Smith, J. W.; Rigby, D.

1981-06-01

D/H ratios in chondritic organic matter are investigated. Demineralized organic residues obtained from previous experiments were dried in a quartz reaction vessel under vacuum for 60 minutes at 250-300 C and then combusted in oxygen for 20 minutes at 850 C. The apparatus is described and the results of the experiments such as D/H ratios in water and measurements on total carbon dioxide are given. Atomic H/C ratios calculated directly from the quantities of carbon dioxide and water recovered, are reported according to Standard Mean Ocean Water and Pee Dee Belemnite, using the customary notation.

Drosophila DH31 Neuropeptide and PDF Receptor Regulate Night-Onset Temperature Preference

PubMed Central

Goda, Tadahiro; Tang, Xin; Umezaki, Yujiro; Chu, Michelle L.

2016-01-01

Body temperature exhibits rhythmic fluctuations over a 24 h period (Refinetti and Menaker, 1992) and decreases during the night, which is associated with sleep initiation (Gilbert et al., 2004; Kräuchi, 2007a,b). However, the underlying mechanism of this temperature decrease is largely unknown. We have previously shown that Drosophila exhibit a daily temperature preference rhythm (TPR), in which their preferred temperatures increase during the daytime and then decrease at the transition from day to night (night-onset) (Kaneko et al., 2012). Because Drosophila are small ectotherms, their body temperature is very close to that of the ambient temperature (Stevenson, 1985), suggesting that their TPR generates their body temperature rhythm. Here, we demonstrate that the neuropeptide diuretic hormone 31 (DH31) and pigment-dispersing factor receptor (PDFR) contribute to regulate the preferred temperature decrease at night-onset. We show that PDFR and tethered-DH31 expression in dorsal neurons 2 (DN2s) restore the preferred temperature decrease at night-onset, suggesting that DH31 acts on PDFR in DN2s. Notably, we previously showed that the molecular clock in DN2s is important for TPR. Although PDF (another ligand of PDFR) is a critical factor for locomotor activity rhythms, Pdf mutants exhibit normal preferred temperature decreases at night-onset. This suggests that DH31-PDFR signaling specifically regulates a preferred temperature decrease at night-onset. Thus, we propose that night-onset TPR and locomotor activity rhythms are differentially controlled not only by clock neurons but also by neuropeptide signaling in the brain. SIGNIFICANCE STATEMENT Body temperature rhythm (BTR) is fundamental for the maintenance of functions essential for homeostasis, such as generating metabolic energy and sleep. One major unsolved question is how body temperature decreases dramatically during the night. Previously, we demonstrated that a BTR-like mechanism, referred to as temperature

48 CFR 245.606 - Inventory schedules.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Inventory schedules. 245.606 Section 245.606 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Contractor Inventory 245.606 Inventory schedules. ...

D/H in Water Evolved from Martian Rocks in Gale Crater

NASA Astrophysics Data System (ADS)

Mahaffy, P. R.; Franz, H. B.; Atreya, S. K.; Webster, C. R.

2017-12-01

The Sample Analysis at Mars (SAM) instrument suite with its Quadrupole Mass Spectrometer (QMS) and Tunable Laser Spectrometer (TSL) measures isotopes such as δ34S in SO2 [1], δ37Cl in HCl [2], δ15N in N2 or NO [3], δ13C in CH4 [4], δ13C and δ18O in CO2 [5-6], δD in H2O [7], and a variety of noble gas isotopes [8-9]. Fractionation of isotopes of H, C, O, N, Ar, and Xe indicates a substantial loss of atmosphere to space. For xenon this may have occurred early in the history of Mars by hydrodynamic escape [10] or spread over time for C, O, N, and Ar [11]. Nevertheless, the detailed history of atmospheric loss and the predictions of the climate when the Gale crater was a lake are still not well constrained. Isotopes from light elements that are presently measured in the atmosphere but that were also locked into minerals in rocks more than 3 billion years ago are of particular interest as they may provide additional constraints on the history of atmospheric loss. These include 15N/14N presently measured in atmospheric N2 [3] but also in nitrogen released from ancient nitrates as NO [12] and D/H in atmospheric water [13] and in water or hydroxyl locked into minerals and released in the SAM evolved gas analysis (EGA) experiments [7]. D/H in water can be measured by both the TSL and the QMS. Typically the D/H decreases over the course of the EGA temperature ramp, since gas that has exchanged with the current atmosphere is released at lower temperatures. Less easily exchanged gas reflecting the D/H ratio in the water of formation of a mineral, such as that from the dehydroxylation of a phylosillicate, is released at higher temperatures. We will examine some of the D/H measurements made on drilled and powdered rocks and the trends in the variation of the D/H ratio with release temperature. We will compare these ratios with the D/H in atmospheric water and discuss possible consequences for loss of D/H over time. References: [1] Franz et al., in press. [2] Farley et al

48 CFR 245.603 - Disposal methods.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Disposal methods. 245.603 Section 245.603 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Contractor Inventory 245.603 Disposal methods. ...

D/H Ratios in Lipids as a Tool to Elucidate Microbial Metabolism

NASA Astrophysics Data System (ADS)

Wijker, Reto S.; Sessions, Alex L.

2016-04-01

Large D/H fractionations have been observed in the lipids and growth water of most organisms studied today. These fractionations have generally been assumed to be constant across most biota because they originate solely from isotope effects imposed by the highly conserved lipid biosynthetic pathway. Recent data is illustrating this conclusion as incomplete. Lipids from field and laboratory samples exhibit huge variations in D/H fractionation. In environmental samples, lipids vary in δD by up to 300 ‰ and in laboratory cultures the documented variation is up to 500 ‰ within the same organism. Remarkably, the isotope fractionation appears to be correlated with the type of metabolism employed by the host organism. However, the underlying biochemical mechanisms leading to these isotopic variations are not yet fully understood. Because the largest proportion of H-bound C in fatty acids is derived directly from NADPH during biosynthesis, the original hypothesis was that large differences in the isotopic composition of NADPH, generated by different central metabolic pathways, were the primary source of D/H variation in lipids. However, recent observations indicate that this cannot be the whole story and lead us to the conclusion that additional processes must affect the isotope composition of NADPH. These processes may include the isotopic exchange of NADPH with water as well as fractionation of NADPH by transhydrogenases, interconverting NADH to NADPH by exhibiting large isotope effects. In this project, our objective is to ascertain whether D/H fractionation and these biochemical processes are correlated. We investigate correlations between cellular NADPH/NADP+ as well as NADH/NAD+ pool sizes and the D/H fractionation in a set of different microorganisms and will present the trends here. Our results will contribute to a more comprehensive understanding of the basic biological regulations over D/H fractionation and potentially enables their use as tracers and

Mars D/H: Implications for Volatile Evolution and Climate History

NASA Astrophysics Data System (ADS)

Jakosky, B. M.; Leshin, L.

2001-05-01

The lighter isotope of H in the martian atmosphere escapes more readily to space than does the heavier D, so that loss to space leaves the atmosphere enriched in D. The observed enrichment in D/H thus is an indicator of the degree of loss. As the H comes primarily from water, it informs the discussion of volatile and climate history. In order to understand the meaning of the enrichment, we need to understand (i) the initial D/H incorporated into the planet at its origin, (ii) the history of outgassing of water to the surface, (iii) atmospheric chemistry and dynamics that results in supply of the upper atmosphere with D and H from H2O in the bulk atmosphere, (iv) current loss rates to space, and (v) the present-day atmospheric D/H ratio. In addition, the D/H ratio can be affected by the exchange of water between the atmosphere and non-atmospheric reservoirs, including the polar caps, the regolith, and the crust, both by diffusion and driven by groundwater circulation (perhaps in hydrothermal systems). There is convincing evidence for the existence of each of these non-atmospheric reservoirs, but only limited information on the history of exchange. The system appears to be sufficiently complex that any attempt to describe it as a two- or three-component system is doomed to failure. Despite this, there are some conclusions for which a compelling case can be made: (i) Enrichment of D/H requires loss of substantial quantities of H to space, with water providing the source. (ii) Improvements in our understanding of the initial and present-day D/H, and the photodissociation of water and supply to the upper atmosphere have changed the quantitative interpretation from a decade ago; as a result, the time-integrated enrichment factor is substantially less than had been previously thought, and the resulting fraction of water lost is less. Roughly 2/3 of the exchangeable water must have been lost. (iii) The unknown time-dependent exchange of water with the polar caps and the

8 CFR 245.10 - Adjustment of status upon payment of additional sum under section 245(i).

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Adjustment of status upon payment of additional sum under section 245(i). 245.10 Section 245.10 Aliens and Nationality DEPARTMENT OF HOMELAND... used in this section the term: (1)(i) Grandfathered alien means an alien who is the beneficiary...

8 CFR 245.10 - Adjustment of status upon payment of additional sum under section 245(i).

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Adjustment of status upon payment of additional sum under section 245(i). 245.10 Section 245.10 Aliens and Nationality DEPARTMENT OF HOMELAND... used in this section the term: (1)(i) Grandfathered alien means an alien who is the beneficiary...

8 CFR 245.10 - Adjustment of status upon payment of additional sum under section 245(i).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Adjustment of status upon payment of additional sum under section 245(i). 245.10 Section 245.10 Aliens and Nationality DEPARTMENT OF HOMELAND... used in this section the term: (1)(i) Grandfathered alien means an alien who is the beneficiary...

8 CFR 245.10 - Adjustment of status upon payment of additional sum under section 245(i).

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Adjustment of status upon payment of additional sum under section 245(i). 245.10 Section 245.10 Aliens and Nationality DEPARTMENT OF HOMELAND... used in this section the term: (1)(i) Grandfathered alien means an alien who is the beneficiary...

8 CFR 245.10 - Adjustment of status upon payment of additional sum under section 245(i).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of status upon payment of additional sum under section 245(i). 245.10 Section 245.10 Aliens and Nationality DEPARTMENT OF HOMELAND... used in this section the term: (1)(i) Grandfathered alien means an alien who is the beneficiary...

Drosophila DH31 Neuropeptide and PDF Receptor Regulate Night-Onset Temperature Preference.

PubMed

Goda, Tadahiro; Tang, Xin; Umezaki, Yujiro; Chu, Michelle L; Kunst, Michael; Nitabach, Michael N; Hamada, Fumika N

2016-11-16

Body temperature exhibits rhythmic fluctuations over a 24 h period (Refinetti and Menaker, 1992) and decreases during the night, which is associated with sleep initiation (Gilbert et al., 2004; Kräuchi, 2007a,b). However, the underlying mechanism of this temperature decrease is largely unknown. We have previously shown that Drosophila exhibit a daily temperature preference rhythm (TPR), in which their preferred temperatures increase during the daytime and then decrease at the transition from day to night (night-onset) (Kaneko et al., 2012). Because Drosophila are small ectotherms, their body temperature is very close to that of the ambient temperature (Stevenson, 1985), suggesting that their TPR generates their body temperature rhythm. Here, we demonstrate that the neuropeptide diuretic hormone 31 (DH31) and pigment-dispersing factor receptor (PDFR) contribute to regulate the preferred temperature decrease at night-onset. We show that PDFR and tethered-DH31 expression in dorsal neurons 2 (DN2s) restore the preferred temperature decrease at night-onset, suggesting that DH31 acts on PDFR in DN2s. Notably, we previously showed that the molecular clock in DN2s is important for TPR. Although PDF (another ligand of PDFR) is a critical factor for locomotor activity rhythms, Pdf mutants exhibit normal preferred temperature decreases at night-onset. This suggests that DH31-PDFR signaling specifically regulates a preferred temperature decrease at night-onset. Thus, we propose that night-onset TPR and locomotor activity rhythms are differentially controlled not only by clock neurons but also by neuropeptide signaling in the brain. Body temperature rhythm (BTR) is fundamental for the maintenance of functions essential for homeostasis, such as generating metabolic energy and sleep. One major unsolved question is how body temperature decreases dramatically during the night. Previously, we demonstrated that a BTR-like mechanism, referred to as temperature preference rhythm (TPR

Novel insights into the algicidal bacterium DH77-1 killing the toxic dinoflagellate Alexandrium tamarense.

PubMed

Yang, Xiaoru; Li, Xinyi; Zhou, Yanyan; Zheng, Wei; Yu, Changping; Zheng, Tianling

2014-06-01

Algicidal bacteria may play a major role in controlling harmful algal blooms (HABs) dynamics. Bacterium DH77-1 was isolated with high algicidal activity against the toxic dinoflagellate Alexandrium tamarense and identified as Joostella sp. DH77-1. The results showed that DH77-1 exhibited algicidal activity through indirect attack, which excreted active substance into the filtrate. It had a relatively wide host range and the active substance of DH77-1 was relatively stable since temperature, pH and storage condition had no obvious effect on the algicidal activity. The algicidal compound from bacterium DH77-1 was isolated based on activity-guided bioassay and the molecular weight was determined to be 125.88 by MALDI-TOF mass spectrometer, however further identification via nuclear magnetic resonance (NMR) spectra is ongoing. The physiological responses of algal cells after exposure to the DH77-1 algicidal substances were as follows: the antioxidant system of A. tamarense responded positively in self-defense; total protein content decreased significantly as did the photosynthetic pigment content; superoxide dismutase, peroxidase enzyme and malondialdehyde content increased extraordinarily and algal cell nucleic acid leaked seriously ultimately inducing cell death. Furthermore, DH77-1 is the first record of a Joostella sp. bacterium being algicidal to the harmful dinoflagellate A. tamarense, and the bacterial culture and the active compounds might be potentially used as a bio-agent for controlling harmful algal blooms. Copyright © 2014 Elsevier B.V. All rights reserved.

Anthocyanin biosynthesis regulation of DhMYB2 and DhbHLH1 in Dendrobium hybrids petals.

PubMed

Li, Chonghui; Qiu, Jian; Ding, Ling; Huang, Mingzhong; Huang, Surong; Yang, Guangsui; Yin, Junmei

2017-03-01

Dendrobium hybrids orchid are popular throughout the world. They have various floral color and pigmentation patterns that are mainly caused by anthocyanins. It is well established that anthocyanin biosynthesis is regulated by the interplay between MYB and bHLH transcription factors (TF) in most plants. In this study, we identified one R2R3-MYB gene, DhMYB2, and one bHLH gene, DhbHLH1, from a Dendrobium hybrid. Their expression profiles were related to anthocyanin pigmentation in Dendrobium petals. Transient over-expression of these two TF genes showed that both DhMYB2 and DhbHLH1 resulted in anthocyanin production in white petals. The interaction between the two TFs was observed in vitro. In different Dendrobium hybrids petals with various pigmentations, DhMYB2 and DhbHLH1 were co-expressed with DhDFR and DhANS, which are regarded as potential regulatory targets of the two TFs. In flowers with distinct purple lips but white or yellow petals/sepals, the expression of DhbHLH1 was only related to anthocyanin accumulation in the lips. Taken together, DhMYB2 interacted with DhbHLH1 to regulate anthocyanin production in Dendrobium hybrid petals. DhbHLH1 was also responsible for the distinct anthocyanin pigmentation in lip tissues. The functional characterization of DhMYB2 and DhbHLH1 will improve understanding of anthocyanin biosynthesis modulation in Dendrobium orchids. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

14 CFR 121.245 - Fire walls.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Fire walls. 121.245 Section 121.245 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS..., FLAG, AND SUPPLEMENTAL OPERATIONS Special Airworthiness Requirements § 121.245 Fire walls. Each engine...

46 CFR 169.245 - Lifesaving equipment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Lifesaving equipment. 169.245 Section 169.245 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Inspections § 169.245 Lifesaving equipment. At each inspection for certification...

46 CFR 169.245 - Lifesaving equipment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Lifesaving equipment. 169.245 Section 169.245 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Inspections § 169.245 Lifesaving equipment. At each inspection for certification...

24 CFR 245.115 - Protected activities.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Protected activities. 245.115 Section 245.115 Housing and Urban Development Regulations Relating to Housing and Urban Development... TENANT PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.115 Protected activities...

24 CFR 245.115 - Protected activities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Protected activities. 245.115 Section 245.115 Housing and Urban Development Regulations Relating to Housing and Urban Development... TENANT PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.115 Protected activities...

24 CFR 245.115 - Protected activities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Protected activities. 245.115 Section 245.115 Housing and Urban Development Regulations Relating to Housing and Urban Development... TENANT PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.115 Protected activities...

24 CFR 245.115 - Protected activities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Protected activities. 245.115 Section 245.115 Housing and Urban Development Regulations Relating to Housing and Urban Development... TENANT PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.115 Protected activities...

8 CFR 245a.36 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false [Reserved] 245a.36 Section 245a.36 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT... AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.36 [Reserved] ...

8 CFR 245a.36 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false [Reserved] 245a.36 Section 245a.36 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.36 [Reserved] ...

8 CFR 245a.21 - Confidentiality.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Confidentiality. 245a.21 Section 245a.21 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.21...

8 CFR 245a.36 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false [Reserved] 245a.36 Section 245a.36 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.36 [Reserved] ...

8 CFR 245a.36 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false [Reserved] 245a.36 Section 245a.36 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT... AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.36 [Reserved] ...

8 CFR 245a.36 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false [Reserved] 245a.36 Section 245a.36 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT... AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.36 [Reserved] ...

8 CFR 245a.21 - Confidentiality.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Confidentiality. 245a.21 Section 245a.21 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.21...

8 CFR 245a.21 - Confidentiality.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Confidentiality. 245a.21 Section 245a.21 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.21...

49 CFR 199.245 - Contractor employees.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Contractor employees. 199.245 Section 199.245... Prevention Program § 199.245 Contractor employees. (a) With respect to those covered employees who are contractors or employed by a contractor, an operator may provide by contract that the alcohol testing...

HIV-1 gp140 epitope recognition is influenced by immunoglobulin DH gene segment sequence

PubMed Central

Wang, Yuge; Kapoor, Pratibha; Parks, Robert; Silva-Sanchez, Aaron; Alam, S. Munir; Verkoczy, Laurent; Liao, Hua-Xin; Zhuang, Yingxin; Burrows, Peter; Levinson, Michael; Elgavish, Ada; Cui, Xiangqin; Haynes, Barton F.; Schroeder, Harry

2015-01-01

Complementarity determining region 3 of the immunoglobulin (Ig) H chain (CDR-H3) lies at the center of the antigen binding site where it often plays a decisive role in antigen recognition and binding. Amino acids encoded by the diversity (DH) gene segment are the main component of CDR-H3. Each DH has the potential to rearrange into one of six DH reading frames (RFs), each of which exhibits a characteristic amino acid hydrophobicity signature that has been conserved among jawed vertebrates by natural selection. A preference for use of RF1 promotes the incorporation of tyrosine into CDR-H3 while suppressing the inclusion of hydrophobic or charged amino acids. To test the hypothesis that these evolutionary constraints on DH sequence influence epitope recognition, we used mice with a single DH that has been altered to preferentially use RF2 or inverted RF1. B cells in these mice produce a CDR-H3 repertoire that is enriched for valine or arginine in place of tyrosine. We serially immunized this panel of mice with gp140 from HIV-1 JR-FL isolate and then used ELISA or peptide microarray to assess antibody binding to key or overlapping HIV-1 envelope epitopes. By ELISA, serum reactivity to key epitopes varied by DH sequence. By microarray, sera with Ig CDR-H3s enriched for arginine bound to linear peptides with a greater range of hydrophobicity, but had a lower intensity of binding than sera containing Ig CDR-H3s enriched for tyrosine or valine. We conclude that patterns of epitope recognition and binding can be heavily influenced by DH germline sequence. This may help explain why antibodies in HIV infected patients must undergo extensive somatic mutation in order to bind to specific viral epitopes and achieve neutralization. PMID:26687685

8 CFR 245a.22 - Rescission.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Rescission. 245a.22 Section 245a.22 Aliens... AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.22 Rescission. (a) Rescission of adjustment of status under LIFE Legalization shall occur only under the...

8 CFR 245a.22 - Rescission.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Rescission. 245a.22 Section 245a.22 Aliens... AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.22 Rescission. (a) Rescission of adjustment of status under LIFE Legalization shall occur only under the...

8 CFR 245a.22 - Rescission.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Rescission. 245a.22 Section 245a.22 Aliens... AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.22 Rescission. (a) Rescission of adjustment of status under LIFE Legalization shall occur only under the...

32 CFR 245.31 - ESCAT test.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false ESCAT test. 245.31 Section 245.31 National... PLAN FOR THE EMERGENCY SECURITY CONTROL OF AIR TRAFFIC (ESCAT) Test Procedures § 245.31 ESCAT test. For...) Tests should normally be conducted in conjunction with scheduled headquarters NORAD approved exercises...

32 CFR 245.31 - ESCAT test.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false ESCAT test. 245.31 Section 245.31 National... PLAN FOR THE EMERGENCY SECURITY CONTROL OF AIR TRAFFIC (ESCAT) Test Procedures § 245.31 ESCAT test. For...) Tests should normally be conducted in conjunction with scheduled headquarters NORAD approved exercises...

43 CFR 24.5 - International agreements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true International agreements. 24.5 Section 24.5... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.5 International agreements. (a) International conventions... boundaries. The authority to enter into such agreements is reserved to the President by and with the advice...

24 CFR 245.120 - Meeting space.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Meeting space. 245.120 Section 245... PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.120 Meeting space. (a) Owners of... of any community room or other available space appropriate for meetings that is part of the...

24 CFR 245.120 - Meeting space.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Meeting space. 245.120 Section 245... PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.120 Meeting space. (a) Owners of... of any community room or other available space appropriate for meetings that is part of the...

24 CFR 245.120 - Meeting space.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Meeting space. 245.120 Section 245... PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.120 Meeting space. (a) Owners of... of any community room or other available space appropriate for meetings that is part of the...

24 CFR 245.120 - Meeting space.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Meeting space. 245.120 Section 245... PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.120 Meeting space. (a) Owners of... of any community room or other available space appropriate for meetings that is part of the...

24 CFR 245.120 - Meeting space.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Meeting space. 245.120 Section 245... PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.120 Meeting space. (a) Owners of... of any community room or other available space appropriate for meetings that is part of the...

SN 2013dh in NGC 5936 is probably a type Iax supernova

NASA Astrophysics Data System (ADS)

Jha, Saurabh W.; McCully, Curtis; Foley, Ryan J.; Cenko, S. Bradley; Zheng, WeiKang; Clubb, Kelsey I.; Shivvers, Isaac; Filippenko, Alexei V.; Tucker, Brad E.; Garnavich, Peter M.

2013-06-01

Further to CBET 3561 (Kumar et al. 2013; Cenko et al. 2013), we have analyzed spectra of SN 2013dh obtained on June 14.3 and June 17.3 UT with the Shane 3-m reflector (+ Kast spectrograph) at Lick Observatory. The observations continue to show that SN 2013dh has a blue continuum with relatively narrow (FWHM approximately 3000 km/s) Fe III absorption.

42 CFR 24.5 - Peer review.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Peer review. 24.5 Section 24.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.5 Peer review. An individual may not be considered for appointment into the SBRS unless his/her...

42 CFR 24.5 - Peer review.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Peer review. 24.5 Section 24.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.5 Peer review. An individual may not be considered for appointment into the SBRS unless his/her...

42 CFR 24.5 - Peer review.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Peer review. 24.5 Section 24.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.5 Peer review. An individual may not be considered for appointment into the SBRS unless his/her...

42 CFR 24.5 - Peer review.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Peer review. 24.5 Section 24.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.5 Peer review. An individual may not be considered for appointment into the SBRS unless his/her...

8 CFR 245a.19 - Interviews.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Interviews. 245a.19 Section 245a.19 Aliens... AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.19 Interviews. (a) All aliens filing applications for adjustment of status with the Service under this section...

8 CFR 245a.19 - Interviews.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Interviews. 245a.19 Section 245a.19 Aliens... AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.19 Interviews. (a) All aliens filing applications for adjustment of status with the Service under this section...

8 CFR 245a.22 - Rescission.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Rescission. 245a.22 Section 245a.22 Aliens... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.22 Rescission. (a) Rescission of adjustment of status under LIFE Legalization shall occur only under the...

8 CFR 245a.19 - Interviews.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Interviews. 245a.19 Section 245a.19 Aliens... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.19 Interviews. (a) All aliens filing applications for adjustment of status with the Service under this section...

8 CFR 245a.22 - Rescission.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Rescission. 245a.22 Section 245a.22 Aliens... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.22 Rescission. (a) Rescission of adjustment of status under LIFE Legalization shall occur only under the...

8 CFR 245a.19 - Interviews.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Interviews. 245a.19 Section 245a.19 Aliens... AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.19 Interviews. (a) All aliens filing applications for adjustment of status with the Service under this section...

20 CFR 627.245 - Work experience.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Work experience. 627.245 Section 627.245... PROGRAMS UNDER TITLES I, II, AND III OF THE ACT Program Requirements § 627.245 Work experience. (a) Definition. Work experience means a short-term or part-time training assignment with a public or private...

20 CFR 627.245 - Work experience.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Work experience. 627.245 Section 627.245... PROGRAMS UNDER TITLES I, II, AND III OF THE ACT Program Requirements § 627.245 Work experience. (a) Definition. Work experience means a short-term or part-time training assignment with a public or private...

D/H Ratios in Lipids as a Tool to Elucidate Microbial Metabolism

NASA Astrophysics Data System (ADS)

Wijker, R. S.; Sessions, A. L.

2015-12-01

Large D/H fractionations have been observed in the lipids and growth water of most organisms studied today. These fractionations have generally been assumed to be constant across most biota because they originate solely from isotope effects imposed by the highly conserved lipid biosynthetic pathway. Recent data is illustrating this conclusion as incomplete. Lipids from field and laboratory samples exhibit huge variations in D/H fractionation. In environmental samples, lipids vary in δD by up to 300 ‰ and in laboratory cultures the documented variation is up to 500 ‰ within the same organism. Remarkably, the isotope fractionation appears to be correlated with the type of metabolism employed by the host organism. However, the underlying biochemical mechanisms leading to these isotopic variations are not yet fully understood. Because the largest proportion of H-bound C in fatty acids is derived directly from NADPH during biosynthesis, the original hypothesis was that large differences in the isotopic composition of NADPH, generated by different central metabolic pathways, were the primary source of D/H variation in lipids. However, recent observations indicate that this cannot be the whole story and lead us to the conclusion that additional processes must affect the isotope composition of NADPH. These processes may include the isotopic exchange of NADPH with water as well as fractionation of NADPH by transhydrogenases, interconverting NADH to NADPH by exhibiting large isotope effects. In this project, our objective is to ascertain whether D/H fractionation and these biochemical processes are correlated. We investigate correlations between cellular NADPH/NADP+ as well as NADH/NAD+ pool sizes and the D/H fractionation in a set of different microorganisms and will present the first trends here. Our results will contribute to a more comprehensive understanding of the basic biological regulations over D/H fractionation and potentially enables their use as tracers and

8 CFR 245.4 - Documentary requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Documentary requirements. 245.4 Section 245.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.4 Documentary requirements. The provisions of part 211 of this chapter relating to the...

8 CFR 245.4 - Documentary requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Documentary requirements. 245.4 Section 245.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.4 Documentary requirements. The provisions of part 211 of this chapter relating to the...

8 CFR 245.4 - Documentary requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Documentary requirements. 245.4 Section 245.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.4 Documentary requirements. The provisions of part 211 of this chapter relating to the...

8 CFR 245.4 - Documentary requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Documentary requirements. 245.4 Section 245.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.4 Documentary requirements. The provisions of part 211 of this chapter relating to the...

8 CFR 245.4 - Documentary requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Documentary requirements. 245.4 Section 245.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.4 Documentary requirements. The provisions of part 211 of this chapter relating to the...

8 CFR 245a.10 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Definitions. 245a.10 Section 245a.10 Aliens... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.10 Definitions. In this Subpart B, the terms: Eligible alien means an alien (including a spouse or child as...

8 CFR 245a.10 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Definitions. 245a.10 Section 245a.10 Aliens... AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.10 Definitions. In this Subpart B, the terms: Eligible alien means an alien (including a spouse or child as...

8 CFR 245a.10 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Definitions. 245a.10 Section 245a.10 Aliens... AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.10 Definitions. In this Subpart B, the terms: Eligible alien means an alien (including a spouse or child as...

8 CFR 245a.10 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Definitions. 245a.10 Section 245a.10 Aliens... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.10 Definitions. In this Subpart B, the terms: Eligible alien means an alien (including a spouse or child as...

8 CFR 245a.10 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Definitions. 245a.10 Section 245a.10 Aliens... AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.10 Definitions. In this Subpart B, the terms: Eligible alien means an alien (including a spouse or child as...

8 CFR 245.5 - Medical examination.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Medical examination. 245.5 Section 245.5... THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.5 Medical examination. Pursuant to section 232(b) of the Act, an applicant for adjustment of status shall be required to have a medical examination by...

8 CFR 245.5 - Medical examination.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Medical examination. 245.5 Section 245.5... THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.5 Medical examination. Pursuant to section 232(b) of the Act, an applicant for adjustment of status shall be required to have a medical examination by...

8 CFR 245.5 - Medical examination.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Medical examination. 245.5 Section 245.5... THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.5 Medical examination. Pursuant to section 232(b) of the Act, an applicant for adjustment of status shall be required to have a medical examination by...

8 CFR 245.5 - Medical examination.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Medical examination. 245.5 Section 245.5... THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.5 Medical examination. Pursuant to section 232(b) of the Act, an applicant for adjustment of status shall be required to have a medical examination by...

8 CFR 245.5 - Medical examination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Medical examination. 245.5 Section 245.5... THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.5 Medical examination. Pursuant to section 232(b) of the Act, an applicant for adjustment of status shall be required to have a medical examination by...

8 CFR 245a.31 - Eligibility.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.31 Eligibility. An alien who is currently in the United States may obtain Family Unity benefits under section 1504 of the LIFE Act... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Eligibility. 245a.31 Section 245a.31 Aliens...

8 CFR 245a.33 - Filing.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Filing. 245a.33 Section 245a.33 Aliens and... NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.33 Filing. (a) General. An application for Family Unity benefits under section 1504 of the LIFE Act Amendments must be filed on a Form I-817...

8 CFR 245a.31 - Eligibility.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.31 Eligibility. An alien who is currently in the United States may obtain Family Unity benefits under section 1504 of the LIFE Act... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Eligibility. 245a.31 Section 245a.31 Aliens...

8 CFR 245a.33 - Filing.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Filing. 245a.33 Section 245a.33 Aliens and... ACT LIFE Act Amendments Family Unity Provisions § 245a.33 Filing. (a) General. An application for Family Unity benefits under section 1504 of the LIFE Act Amendments must be filed on a Form I-817...

8 CFR 245a.33 - Filing.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Filing. 245a.33 Section 245a.33 Aliens and... ACT LIFE Act Amendments Family Unity Provisions § 245a.33 Filing. (a) General. An application for Family Unity benefits under section 1504 of the LIFE Act Amendments must be filed on a Form I-817...

8 CFR 245a.31 - Eligibility.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.31 Eligibility. An alien who is currently in the United States may obtain Family Unity benefits under section 1504 of the LIFE Act... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Eligibility. 245a.31 Section 245a.31 Aliens...

8 CFR 245a.31 - Eligibility.

Code of Federal Regulations, 2010 CFR

2010-01-01

... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.31 Eligibility. An alien who is currently in the United States may obtain Family Unity benefits under section 1504 of the LIFE... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Eligibility. 245a.31 Section 245a.31 Aliens...

8 CFR 245a.31 - Eligibility.

Code of Federal Regulations, 2011 CFR

2011-01-01

... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.31 Eligibility. An alien who is currently in the United States may obtain Family Unity benefits under section 1504 of the LIFE... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Eligibility. 245a.31 Section 245a.31 Aliens...

8 CFR 245a.33 - Filing.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Filing. 245a.33 Section 245a.33 Aliens and... ACT LIFE Act Amendments Family Unity Provisions § 245a.33 Filing. (a) General. An application for Family Unity benefits under section 1504 of the LIFE Act Amendments must be filed on a Form I-817...

32 CFR 245.27 - Data entry.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Data entry. 245.27 Section 245.27 National... Under ESCAT § 245.27 Data entry. Aircraft will file IFR or VFR flight plans, assigned a discrete... entered in the remarks section of the flight plan. The EATPL number will be passed with flight plan data...

32 CFR 245.27 - Data entry.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Data entry. 245.27 Section 245.27 National... Under ESCAT § 245.27 Data entry. Aircraft will file IFR or VFR flight plans, assigned a discrete... entered in the remarks section of the flight plan. The EATPL number will be passed with flight plan data...

32 CFR 245.27 - Data entry.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Data entry. 245.27 Section 245.27 National... Under ESCAT § 245.27 Data entry. Aircraft will file IFR or VFR flight plans, assigned a discrete... entered in the remarks section of the flight plan. The EATPL number will be passed with flight plan data...

32 CFR 245.27 - Data entry.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Data entry. 245.27 Section 245.27 National... Under ESCAT § 245.27 Data entry. Aircraft will file IFR or VFR flight plans, assigned a discrete... entered in the remarks section of the flight plan. The EATPL number will be passed with flight plan data...

32 CFR 245.27 - Data entry.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Data entry. 245.27 Section 245.27 National... Under ESCAT § 245.27 Data entry. Aircraft will file IFR or VFR flight plans, assigned a discrete... entered in the remarks section of the flight plan. The EATPL number will be passed with flight plan data...

D/H and Water Concentrations of Submarine MORB Glass Around the World: Analytical Aspects, Standardization, and (re)defining Mantle D/H Ranges

NASA Astrophysics Data System (ADS)

Bindeman, I. N.; Dixon, J. E.; Langmuir, C. H.; Palandri, J. L.

2015-12-01

The advent and calibration of the Thermal Combustion Element Analyzer (TCEA) continuous flow system coupled with the large-radius mass spectrometer MAT253 permits precise (±0.02 wt.% H2O, ±1-3‰ D/H) measurements in 1-10 mg of volcanic glass (0.1 wt.% H2O requires ~10 mg glass), which permits the targeting of small amounts of the freshest concentrate. This is a >100 factor reduction in sample size over conventional methods, four times over more common Delta series instruments. We investigated in triplicate 115 samples of submarine MORB glasses ranging from water-poor (0.1-0.2wt%) to water-rich (1.2-1.5wt%). These samples were previously investigated for major and trace elements, radiogenic isotopes; a large subset of these samples coming from the FAZAR expedition were studied previously by FTIR for water concentration. We also ran samples previously studied by the conventional off-line technique: MORB glass including those from the Easter Platform and the Alvin 526-1 standard (0.2wt% H2O). We observe excellent 1:1 correspondence (1.02x+0.02, R2=0.94) of wt% water by FTIR and TCEA suggesting complete extraction of water and no dependence on water concentration. We measure 51‰ total range in D/H that correlates with all other chemical and isotopic indicators of mantle enrichment, with the heaviest values occurring in the most enriched samples. When used uncorrected values of H2 gas run against H2 gas of known composition, this range agrees nicely with previous D/H range for MORB (-30 to -90‰), measured for samples run conventionally. Uncorrected analyses of Alvin glass 526-1 gives -66‰. When run against SMOW, SLAP and -41‰ water sealed in silver cups, the range is shifted by -15‰; when standardization is done by with three commonly used mica standards as is done most commonly in different labs, the range is shifted downward by -30-32‰. There are no isotopic offsets related to total water or D/H range requiring different slope or non-linear correction

48 CFR 245.612 - Removal and storage.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Removal and storage. 245.612 Section 245.612 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Contractor Inventory 245.612 Removal and storage. ...

33 CFR 104.245 - Communications.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Communications. 104.245 Section... MARITIME SECURITY: VESSELS Vessel Security Requirements § 104.245 Communications. (a) The Vessel Security... board the vessel. (b) Communications systems and procedures must allow effective and continuous...

33 CFR 104.245 - Communications.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Communications. 104.245 Section... MARITIME SECURITY: VESSELS Vessel Security Requirements § 104.245 Communications. (a) The Vessel Security... board the vessel. (b) Communications systems and procedures must allow effective and continuous...

33 CFR 104.245 - Communications.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Communications. 104.245 Section... MARITIME SECURITY: VESSELS Vessel Security Requirements § 104.245 Communications. (a) The Vessel Security... board the vessel. (b) Communications systems and procedures must allow effective and continuous...

33 CFR 104.245 - Communications.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Communications. 104.245 Section... MARITIME SECURITY: VESSELS Vessel Security Requirements § 104.245 Communications. (a) The Vessel Security... board the vessel. (b) Communications systems and procedures must allow effective and continuous...

32 CFR 245.15 - Appropriate military authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Appropriate military authority. 245.15 Section 245.15 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE... Implementation of ESCAT § 245.15 Appropriate military authority. Appropriate military authority will take the...

32 CFR 245.1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (DOT/FAA), Department of Homeland Security/Transportation Security Administration (DHS/TSA), and Department of Defense (DoD) authorities for the security control of civil and military air traffic. It... 32 National Defense 2 2014-07-01 2014-07-01 false Purpose. 245.1 Section 245.1 National Defense...

32 CFR 245.1 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (DOT/FAA), Department of Homeland Security/Transportation Security Administration (DHS/TSA), and Department of Defense (DoD) authorities for the security control of civil and military air traffic. It... 32 National Defense 2 2011-07-01 2011-07-01 false Purpose. 245.1 Section 245.1 National Defense...

32 CFR 245.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (DOT/FAA), Department of Homeland Security/Transportation Security Administration (DHS/TSA), and Department of Defense (DoD) authorities for the security control of civil and military air traffic. It... 32 National Defense 2 2010-07-01 2010-07-01 false Purpose. 245.1 Section 245.1 National Defense...

32 CFR 245.1 - Purpose.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (DOT/FAA), Department of Homeland Security/Transportation Security Administration (DHS/TSA), and Department of Defense (DoD) authorities for the security control of civil and military air traffic. It... 32 National Defense 2 2013-07-01 2013-07-01 false Purpose. 245.1 Section 245.1 National Defense...

32 CFR 245.1 - Purpose.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (DOT/FAA), Department of Homeland Security/Transportation Security Administration (DHS/TSA), and Department of Defense (DoD) authorities for the security control of civil and military air traffic. It... 32 National Defense 2 2012-07-01 2012-07-01 false Purpose. 245.1 Section 245.1 National Defense...

42 CFR 137.245 - What is retrocession?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false What is retrocession? 137.245 Section 137.245 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.245 What is retrocession...

Complete Genome Sequence of NEB 5-alpha, a Derivative of Escherichia coli K-12 DH5α.

PubMed

Anton, Brian P; Raleigh, Elisabeth A

2016-11-10

Escherichia coli K-12 DH5α is one of the most popular and widely available laboratory strains, but, surprisingly, no complete genome sequence has been publicly available. Here, we report the complete, finished sequence of NEB 5-alpha (DH5α fhuA2). It should serve as a useful reference for researchers working with DH5α. Copyright © 2016 Anton and Raleigh.

9 CFR 354.245 - Vermin.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Vermin. 354.245 Section 354.245 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... exclude flies, rats, mice, and other vermin from the official plant. Dogs, cats, and other pets shall be...

A human thyroid cancer cell line, DH-14-3, newly established from poorly differentiated thyroid carcinoma.

PubMed

Teshima, Jin; Doi, Hideyuki; Fujimori, Keisei; Watanabe, Michio; Nakajima, Noriaki; Nakano, Tomoyuki; Takahashi, Yoshio; Ohuchi, Noriaki; Satomi, Susumu

2013-06-01

Poorly differentiated thyroid carcinoma (PDTC) is a newly recognized histological type of malignant thyroid tumor, accounting for about 2 - 13% of all thyroid carcinomas. PDTC is considered as a morphologically and biologically intermediate stage between well-differentiated thyroid carcinoma and anaplastic thyroid carcinoma. PDTC preferentially manifests bone metastases. We here established a cell line from a resected tumor specimen from a 70-year-old male patient with PDTC who presented with multiple bone metastases. This new thyroid tumor cell line was designated as DH-14-3 and was subsequently grown in culture for several years. DH-14-3 cells express thyroglobulin in the cytoplasm and thyroid transcription factor-1 in the nuclei, both proteins of which are specific markers for the thyroid gland. Importantly, triiodothyronine (T3) was detected in the cultured medium of DH-14-3 cells, in which, however, thyroxine (T4) was undetectable. Moreover, DH-14-3 cells secreted interleukin-8, transforming growth factor-β1, vascular endothelial growth factor, matrix metalloproteinase-1 and parathyroid hormone-related protein, all of which may be responsible for the aggressiveness or bone metastasis of PDTC. Thus, the production of these proteins may reflect the metastatic potential of this cell line. DH-14-3 cells also express CXC chemokine receptor-4 and epidermal growth factor receptor, and carry a missense mutation in the p53 tumor suppressor gene. In fact, transplantation of DH-14-3 cells into the back of nude mice resulted in the formation of tumors, thereby confirming the capability of tumorigenesis. DH-14-3 cells may be useful for investigating the biological features of PDTC and will contribute to the therapeutic study of thyroid cancer.

8 CFR 245a.32 - Ineligible aliens.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Ineligible aliens. 245a.32 Section 245a.32 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.32 Ineligible aliens. The...

8 CFR 245a.32 - Ineligible aliens.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Ineligible aliens. 245a.32 Section 245a.32 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.32 Ineligible aliens. The...

8 CFR 245a.32 - Ineligible aliens.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Ineligible aliens. 245a.32 Section 245a.32 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.32 Ineligible aliens. The...

8 CFR 245a.32 - Ineligible aliens.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Ineligible aliens. 245a.32 Section 245a.32 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.32 Ineligible aliens. The...

8 CFR 245a.32 - Ineligible aliens.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Ineligible aliens. 245a.32 Section 245a.32 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.32 Ineligible aliens. The...

8 CFR 245a.17 - Citizenship skills.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Citizenship skills. 245a.17 Section 245a.17 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.17...

8 CFR 245a.17 - Citizenship skills.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Citizenship skills. 245a.17 Section 245a.17 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.17...

8 CFR 245a.17 - Citizenship skills.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Citizenship skills. 245a.17 Section 245a.17 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.17...

42 CFR 403.245 - Loss of certification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Loss of certification. 403.245 Section 403.245 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL...: General Provisions § 403.245 Loss of certification. (a) A policy loses certification if— (1) The insuring...

40 CFR 35.245 - Maximum federal share.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Maximum federal share. 35.245 Section 35.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE... (section 23(a)(2)) § 35.245 Maximum federal share. The Regional Administrator may provide up to 50 percent...

19 CFR 24.5 - Filing identification number.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Filing identification number. 24.5 Section 24.5... TREASURY CUSTOMS FINANCIAL AND ACCOUNTING PROCEDURE § 24.5 Filing identification number. (a) Generally..., Notification of Importer's Number or Application for Importer's Number, or Notice of Change of Name or Address...

19 CFR 24.5 - Filing identification number.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Filing identification number. 24.5 Section 24.5... TREASURY CUSTOMS FINANCIAL AND ACCOUNTING PROCEDURE § 24.5 Filing identification number. (a) Generally..., Notification of Importer's Number or Application for Importer's Number, or Notice of Change of Name or Address...

19 CFR 24.5 - Filing identification number.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Filing identification number. 24.5 Section 24.5... TREASURY CUSTOMS FINANCIAL AND ACCOUNTING PROCEDURE § 24.5 Filing identification number. (a) Generally..., Notification of Importer's Number or Application for Importer's Number, or Notice of Change of Name or Address...

48 CFR 245.7302 - Competitive sales.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Competitive sales. 245..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Sale of Surplus Contractor Inventory 245.7302 Competitive sales. ...

48 CFR 245.107 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... clause at 252.245-7000, Government-Furnished Mapping, Charting, and Geodesy Property, in solicitations andcontracts when mapping, charting, and geodesy property is to be furnished. (b) Use the clause at 252.245...

Influence of strain rate on the structure/property behavior of the alpha-2 alloy Ti-24.5Al-10.5Nb-1.5Mo

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gray, G.T. III; Hong, Sun Ig; Marquardt, B.J.

Preliminary dislocation g{center_dot}b analysis revealed that following room temperature deformation at low strain rate the majority of the dislocations are a-dislocations lying on basal planes, 2nd order pyramidal (a/2 + c) slip on [1211], and 1st order pyramidal a-slip on [1011]. Increasing the rate of deformation at room temperature to 6000 s{sup {minus}1} is seen to result in increased a-slip on prism planes and a decreased amount of basal slip. At high-strain-rates and elevated temperatures the substructure was seen to be generally similar to that observed following high-rate deformation at room temperature except for an increased amount of basal slipmore » and a somewhat higher incidence of 2nd order pyramidal slip. The defect generation and the rate sensitivity of Ti-24.5Al-10.5Nb-1.5Mo are discussed as a function of strain rate and temperature and contrasted to that observed in conventional titanium alloys and TiAl.« less

Identification and Expression Analysis of Diapause Hormone and Pheromone Biosynthesis Activating Neuropeptide (DH-PBAN) in the Legume Pod Borer, Maruca vitrata Fabricius

PubMed Central

Chang, Jian-Cheng; Ramasamy, Srinivasan

2014-01-01

Neuropeptides play essential roles in a variety of physiological responses that contribute to the development and reproduction of insects. Both the diapause hormone (DH) and pheromone biosynthesis activating neuropeptide (PBAN) belong to the PBAN/pyrokinin neuropeptide family, which has a conserved pentapeptide motif FXPRL at the C-terminus. We identified the full-length cDNA encoding DH-PBAN in Maruca vitrata, a major lepidopteran pest of leguminous crops. The open reading frame of Marvi-DH-PBAN is 591 bp in length, encoding 197 amino acids, from which five putative neuropeptides [DH, PBAN, α-subesophageal ganglion neuropeptide (SGNP), β-SGNP and γ-SGNP] are derived. Marvi-DH-PBAN was highly similar (83%) to DH-PBAN of Omphisa fuscidentalis (Lepidoptera: Crambidae), but possesses a unique C-terminal FNPRL motif, where asparagine has replaced a serine residue present in other lepidopteran PBAN peptides. The genomic DNA sequence of Marvi-DH-PBAN is 6,231 bp in size and is composed of six exons. Phylogenetic analysis has revealed that the Marvi-DH-PBAN protein sequence is closest to its homolog in Crambidae, but distant from Diptera, Coleoptera and Hymenoptera DH-PBAN, which agrees with the current taxonomy. DH-PBAN transcripts were present in the head and thoracic complex, but absent in the abdomen of M. vitrata. Real-time quantitative PCR assays have demonstrated a relatively higher expression of Marvi-DH-PBAN mRNA in the latter half of the pupal stages and in adults. These findings represent a significant step forward in our understanding of the DH-PBAN gene architecture and phylogeny, and raise the possibility of using Marvi-DH-PBAN to manage M. vitrata populations through molecular techniques. PMID:24409312

48 CFR 245.602 - Reutilization of Government property.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Government property. 245.602 Section 245.602 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Reutilization, and Disposal 245.602 Reutilization of Government property. ...

insilico Characterization and Homology Modeling of Arabitol Dehydrogenase (ArDH) from Candida albican.

PubMed

Sarwar, Muhammad Waseem; Saleem, Irum Baddisha; Ali, Asif; Abbas, Farhat

2013-01-01

Arabitol dehydrogenase (ArDH) is involved in the production of different sugar alcohols like arabitol, sorbitol, mannitol, erythritol and xylitol by using five carbon sugars as substrate. Arabinose, d-ribose, d-ribulose, xylose and d-xylulose are known substrate of this enzyme. ArDH is mainly produced by osmophilic fungi for the conversion of ribulose to arabitol under stress conditions. Recently this enzyme has been used by various industries for the production of pharmaceutically important sugar alcohols form cheap source than glucose. But the information at structure level as well as its binding energy analysis with different substrates was missing. The present study was focused on sequence analysis, insilico characterization and substrate binding analysis of ArDH from a fungus specie candida albican. Sequence analysis and physicochemical properties showed that this protein is highly stable, negatively charged and having more hydrophilic regions, these properties made this enzyme to bind with number of five carbon sugars as substrate. The predicted 3D model will helpful for further structure based studies. Docking analysis provided free energies of binding of each substrate from a best pose as arabinose -9.8224calK/mol, dribose -11.3701Kcal/mol, d-ribulose -8.9230Kcal/mol, xylose -9.7007Kcal/mol and d-xylulose 9.7802Kcal/mol. Our study provided insight information of structure and interactions of ArDH with its substrate. These results obtained from this study clearly indicate that d-ribose is best substrate for ArDH for the production of sugar alcohols. This information will be helpful for better usage of this enzyme for hyper-production of sugar alcohols by different industries.

insilico Characterization and Homology Modeling of Arabitol Dehydrogenase (ArDH) from Candida albican

PubMed Central

Sarwar, Muhammad Waseem; Saleem, Irum Baddisha; Ali, Asif; Abbas, Farhat

2013-01-01

Background: Arabitol dehydrogenase (ArDH) is involved in the production of different sugar alcohols like arabitol, sorbitol, mannitol, erythritol and xylitol by using five carbon sugars as substrate. Arabinose, d-ribose, d-ribulose, xylose and d-xylulose are known substrate of this enzyme. ArDH is mainly produced by osmophilic fungi for the conversion of ribulose to arabitol under stress conditions. Recently this enzyme has been used by various industries for the production of pharmaceutically important sugar alcohols form cheap source than glucose. But the information at structure level as well as its binding energy analysis with different substrates was missing. Results: The present study was focused on sequence analysis, insilico characterization and substrate binding analysis of ArDH from a fungus specie candida albican. Sequence analysis and physicochemical properties showed that this protein is highly stable, negatively charged and having more hydrophilic regions, these properties made this enzyme to bind with number of five carbon sugars as substrate. The predicted 3D model will helpful for further structure based studies. Docking analysis provided free energies of binding of each substrate from a best pose as arabinose -9.8224calK/mol, dribose -11.3701Kcal/mol, d-ribulose -8.9230Kcal/mol, xylose -9.7007Kcal/mol and d-xylulose 9.7802Kcal/mol. Conclusion: Our study provided insight information of structure and interactions of ArDH with its substrate. These results obtained from this study clearly indicate that d-ribose is best substrate for ArDH for the production of sugar alcohols. This information will be helpful for better usage of this enzyme for hyper-production of sugar alcohols by different industries. PMID:24391356

46 CFR 170.245 - Foam flotation material.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Foam flotation material. 170.245 Section 170.245... REQUIREMENTS FOR ALL INSPECTED VESSELS Special Installations § 170.245 Foam flotation material. (a) Installation of foam must be approved by the OCMI. (b) If foam is used to comply with § 171.070(d), § 171.095(c...

46 CFR 170.245 - Foam flotation material.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Foam flotation material. 170.245 Section 170.245... REQUIREMENTS FOR ALL INSPECTED VESSELS Special Installations § 170.245 Foam flotation material. (a) Installation of foam must be approved by the OCMI. (b) If foam is used to comply with § 171.070(d), § 171.095(c...

32 CFR 245.9 - Authority.

Code of Federal Regulations, 2011 CFR

2011-07-01

... to the Secretary of Homeland Security, February 28, 2003. (d) Title 10 U.S.C.—Armed Forces. (e) Title... aviation security responsibilities from FAA to TSA. (h) Homeland Security Act of 2002 (Pub. L. 107-296... 32 National Defense 2 2011-07-01 2011-07-01 false Authority. 245.9 Section 245.9 National Defense...

32 CFR 245.9 - Authority.

Code of Federal Regulations, 2014 CFR

2014-07-01

... to the Secretary of Homeland Security, February 28, 2003. (d) Title 10 U.S.C.—Armed Forces. (e) Title... aviation security responsibilities from FAA to TSA. (h) Homeland Security Act of 2002 (Pub. L. 107-296... 32 National Defense 2 2014-07-01 2014-07-01 false Authority. 245.9 Section 245.9 National Defense...

32 CFR 245.9 - Authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... to the Secretary of Homeland Security, February 28, 2003. (d) Title 10 U.S.C.—Armed Forces. (e) Title... aviation security responsibilities from FAA to TSA. (h) Homeland Security Act of 2002 (Pub. L. 107-296... 32 National Defense 2 2010-07-01 2010-07-01 false Authority. 245.9 Section 245.9 National Defense...

32 CFR 245.9 - Authority.

Code of Federal Regulations, 2013 CFR

2013-07-01

... to the Secretary of Homeland Security, February 28, 2003. (d) Title 10 U.S.C.—Armed Forces. (e) Title... aviation security responsibilities from FAA to TSA. (h) Homeland Security Act of 2002 (Pub. L. 107-296... 32 National Defense 2 2013-07-01 2013-07-01 false Authority. 245.9 Section 245.9 National Defense...

32 CFR 245.9 - Authority.

Code of Federal Regulations, 2012 CFR

2012-07-01

... to the Secretary of Homeland Security, February 28, 2003. (d) Title 10 U.S.C.—Armed Forces. (e) Title... aviation security responsibilities from FAA to TSA. (h) Homeland Security Act of 2002 (Pub. L. 107-296... 32 National Defense 2 2012-07-01 2012-07-01 false Authority. 245.9 Section 245.9 National Defense...

Choice of Bond Dissociation Enthalpies on which to Base the Stabilization Energies of Simple Radicals: DH(R-H)is Preferred because DH(R-Me) is Perturbed by Changes in Chain Branching

DOE Office of Scientific and Technical Information (OSTI.GOV)

Poutsma, Marvin L

2008-01-01

The relative stabilization energies of radicals, SE(R ), along the simple series methyl/ethyl/i-propyl/t-butyl are known to vary in spread and even direction dependent on which dissociation enthalpies, DH(R-X), they are based on. Using a highly electronegative X is recognized as unwise, but it is not clear whether a choice of X = Me or X = R might not be preferred over the almost universal use of R = H. The enthalpies of isomerization of C4 radical pairs that vary only in the substitution pattern at the radical center but not in carbon skeleton illustrate that R = H ismore » indeed the better choice. Comparisons in the context of recent predictive models for alkane and radical stability indicate that, while relative DH(R-H) values highlight the desired difference in substitution pattern at the radical center, relative DH(R-Me) values are perturbed by differences in skeletal branching or protobranching which are well-known to affect thermochemistry. As a result, SE(R ) values derived from relative DH(R-Me) values are consistently too small. The same pattern is illustrated for prim, sec, and tert allylic and benzylic radicals (larger SE(R )) and for the parent vinyl, phenyl, and ethynyl radicals (negative SE(R )).« less

The NRF2 activator DH404 attenuates adverse ventricular remodeling post-myocardial infarction by modifying redox signalling.

PubMed

Bubb, Kristen J; Kok, Cindy; Tang, Owen; Rasko, Nathalie B; Birgisdottir, Asa B; Hansen, Thomas; Ritchie, Rebecca; Bhindi, Ravinay; Reisman, Scott A; Meyer, Colin; Ward, Keith; Karimi Galougahi, Keyvan; Figtree, Gemma A

2017-07-01

The novel synthetic triterpenoid, bardoxolone methyl, has the ability to upregulate cytoprotective proteins via induction of the nuclear factor erythroid-2-related factor 2 (Nrf2) pathway. This makes it a promising therapeutic agent in disease states characterized by dysregulated oxidative signalling. We have examined the effect of a Nrf2 activator, dihydro-CDDO-trifluoroethyl amide (DH404), a derivative of bardoxolone methyl, on post-infarct cardiac remodeling in rats. DH404, administered from day 2 post myocardial infarction (MI: 30min transient ischemia followed by reperfusion) resulted in almost complete protection against adverse ventricular remodeling as assessed at day 28 (left ventricular end-systolic area: sham 0.14±0.01cm 2 , MI vehicle 0.29±0.04cm 2 vs. MI DH404 0.18±0.02cm 2 , P<0.05); infarct size (21.3±3.4% MI vehicle vs. 10.9±2.3% MI DH404, P<0.05) with associated benefits on systolic function (fractional shortening: sham 71.9±2.6%, MI vehicle 36.2±1.9% vs. MI DH404 58.6±4.0%, P<0.05). These structural and functional benefits were associated with lower myocardial expression of atrial natriuretic peptide (ANP, P<0.01 vs. MI vehicle), and decreased fibronectin (P<0.01 vs. MI vehicle) in DH404-treated MI rats at 28 days. MI increased glutathionylation of endothelial nitric oxide synthase (eNOS) in vitro - a molecular switch that uncouples the enzyme, increasing superoxide production and decreasing nitric oxide (NO) bioavailability. MI-induced eNOS glutathionylation was substantially ameliorated by DH404. An associated increase in glutaredoxin 1 (Grx1) co-immunoprecipitation with eNOS without a change in expression was mechanistically intriguing. Indeed, in parallel in vitro experiments, silencing of Grx1 abolished the protective effect of DH404 against Angiotensin II-induced eNOS uncoupling. The bardoxolone derivative DH404 significantly attenuated cardiac remodeling post MI, at least in part, by re-coupling of eNOS and increasing the functional

48 CFR 245.608 - Screening of contractor inventory.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Screening of contractor inventory. 245.608 Section 245.608 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Disposal of Contractor Inventory 245.608 Screening of contractor inventory. ...

Recognizing the Effects of Terrestrial Contamination on D/H Ratios in Shergottite Phosphates

NASA Technical Reports Server (NTRS)

Ross, D. K.; Ito, M.; Hervig, R.; Rao, M. N.; Nyquist, L. E.

2011-01-01

Hydrogen isotope ratios in shergottite phosphate minerals have been investigated by SIMS in the meteorites Queen Alexandra Range (QUE) 94201 and Los Angeles. We have also collected electron probe data on these phosphates in order to characterize the phosphate minerals and attempt to document any potential hydrogen isotopic differences between chlor-apatite and whitlockite. In the section of Los Angeles we studied (748), we found both chlor-apatite and whitlockite, but in the section of QUE 94201,38 studied, we found only whitlockite. In both meteorites, D/H ratios (expressed in units of delta D (sub SMOW) vary, from terrestrial values up to approximately 5400%o in QUE 94201, and to approximately 3800%o in Los Angeles. We have carefully examined the ion probed pits with high-resolution FE-SEM. In most cases where the D/H ratios are low, we have iden-tified cracks that instersect the ion probe pit. These cracks are not visible in the optical microscope attached to the SIMS instument, making them impossible to avoid during SIMS data collection. We contend that the low ratios are a function of substantial terrestrial contamination, and that similar contamination is a likely factor in previously published studies on D/H ratios in martian phosphates. Here we highlight the difficulty of attempts to constrain the martian mantle D/H ratio using phosphate data, given that both terrestrial contamination and martian mantle hydrogen will move phosphate D/H ratios in the same direction, toward lower values. We note that our data include some of the most deuterium-rich values ever reported for martian phosphates. It is clear that some of our measurements are only minimally or totally uncontaminated, but the question arises, are intermediate values diminished because of true martian variability, or do they reflect contamination?

The corticotropin-releasing factor-like diuretic hormone 44 (DH44) and kinin neuropeptides modulate desiccation and starvation tolerance in Drosophila melanogaster.

PubMed

Cannell, Elizabeth; Dornan, Anthony J; Halberg, Kenneth A; Terhzaz, Selim; Dow, Julian A T; Davies, Shireen-A

2016-06-01

Malpighian tubules are critical organs for epithelial fluid transport and stress tolerance in insects, and are under neuroendocrine control by multiple neuropeptides secreted by identified neurons. Here, we demonstrate roles for CRF-like diuretic hormone 44 (DH44) and Drosophila melanogaster kinin (Drome-kinin, DK) in desiccation and starvation tolerance. Gene expression and labelled DH44 ligand binding data, as well as highly selective knockdowns and/or neuronal ablations of DH44 in neurons of the pars intercerebralis and DH44 receptor (DH44-R2) in Malpighian tubule principal cells, indicate that suppression of DH44 signalling improves desiccation tolerance of the intact fly. Drome-kinin receptor, encoded by the leucokinin receptor gene, LKR, is expressed in DH44 neurons as well as in stellate cells of the Malpighian tubules. LKR knockdown in DH44-expressing neurons reduces Malpighian tubule-specific LKR, suggesting interactions between DH44 and LK signalling pathways. Finally, although a role for DK in desiccation tolerance was not defined, we demonstrate a novel role for Malpighian tubule cell-specific LKR in starvation tolerance. Starvation increases gene expression of epithelial LKR. Also, Malpighian tubule stellate cell-specific knockdown of LKR significantly reduced starvation tolerance, demonstrating a role for neuropeptide signalling during starvation stress. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Evaluation of the Susceptibility to SCC Initiation of Alloy 690 in Simulated PWR Primary Water

NASA Astrophysics Data System (ADS)

Tsutsumi, Kazuya; Couvant, Thierry

Alloy 690 has been widely used in fabricating components of LWR plants as an alternative material to Alloy 600 which has exhibited a significant susceptibility to PWSCC. However, some authors have reported that Alloy 690 can suffer a significant susceptibility to SCC crack growth when highly cold worked. While most of the recent studies emphasize SCC propagation phase, EDF and its partners are focusing on the material's resistance to SCC initiation. This paper summarizes the current work carried out at EDF MAI on the SCC initiation. By means of constant elongation rate tests (CERTs) and constant displacement tests, experimental investigation of the susceptibility to PWSCC were performed. No SCC was observed on either an extruded bar or on two plates, even after 24%-1D cold rolling, confirming the superior PWSCC resistance of Alloy 690 independent of a amount of intergranular precipitation of carbides, and also revealing that such cold rolling does not necessarily decrease the resistance to SCC. On the other hand, a experimental steam generator tube that has a degraded microstructure due to specific heat-treatment revealed its susceptibility to SCC, probably because of the interactive effect of microstructure with heavy intragranular carbide precipitations and the cold worked superficial layer. This phenomenon is in good agreement with results previously published. In this study, the maximal crack depth slightly increased when DH increased from 5 to 60 cc.kg-1H2O. No significant prior ageing effect on the crack depth was observed, even when ageing was combined with high DH.

48 CFR 245.7204 - Preparing inventory disposal report.

Code of Federal Regulations, 2010 CFR

2010-10-01

... disposal report. 245.7204 Section 245.7204 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Special Instructions 245... any other activities having an interest in the inventory disposal. (c) Items on the form are self...

48 CFR 245.7308 - Antitrust notification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... calendar or fiscal year); (10) Estimated net worth of proposed purchaser; and (11) Intended use of property... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Antitrust notification. 245.7308 Section 245.7308 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS...

48 CFR 245.7306 - Sales services.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Sales services. 245.7306... OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Sale of Surplus Contractor Inventory 245.7306 Sales services. When sale services are needed, the plant clearance officer will document the reasons in...

32 CFR 245.12 - Amplifying instructions.

Code of Federal Regulations, 2011 CFR

2011-07-01

.... These supplements are to consider the special requirement of organized civil defense and disaster relief... 32 National Defense 2 2011-07-01 2011-07-01 false Amplifying instructions. 245.12 Section 245.12 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED...

8 CFR 245a.30 - Description of program.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Description of program. 245a.30 Section 245a.30 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF... OF THE IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.30...

8 CFR 245a.30 - Description of program.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Description of program. 245a.30 Section 245a.30 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF... OF THE IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.30...

8 CFR 245a.30 - Description of program.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Description of program. 245a.30 Section 245a.30 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.30 Description of program...

8 CFR 245a.30 - Description of program.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Description of program. 245a.30 Section 245a.30 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.30 Description of program...

8 CFR 245a.30 - Description of program.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Description of program. 245a.30 Section 245a.30 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF... IMMIGRATION AND NATIONALITY ACT LIFE Act Amendments Family Unity Provisions § 245a.30 Description of program...

43 CFR 24.5 - International agreements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false International agreements. 24.5 Section 24... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.5 International agreements. (a) International conventions... boundaries. The authority to enter into such agreements is reserved to the President by and with the advice...

43 CFR 24.5 - International agreements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false International agreements. 24.5 Section 24... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.5 International agreements. (a) International conventions... boundaries. The authority to enter into such agreements is reserved to the President by and with the advice...

7 CFR 58.245 - Method of sample analysis.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Method of sample analysis. 58.245 Section 58.245... Procedures § 58.245 Method of sample analysis. Samples shall be tested according to the applicable methods of laboratory analysis contained in either DA Instruction 918-RL as issued by the USDA, Agricultural Marketing...

27 CFR 44.245 - Strengthening bond.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2014-04-01 2014-04-01 false Strengthening bond. 44.245....245 Strengthening bond. Where the appropriate TTB officer determines that the amount of the bond... appropriate TTB officer may require the proprietor to file a strengthening bond in an appropriate amount with...

27 CFR 44.245 - Strengthening bond.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Strengthening bond. 44.245....245 Strengthening bond. Where the appropriate TTB officer determines that the amount of the bond... appropriate TTB officer may require the proprietor to file a strengthening bond in an appropriate amount with...

27 CFR 44.245 - Strengthening bond.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2012-04-01 2011-04-01 true Strengthening bond. 44.245....245 Strengthening bond. Where the appropriate TTB officer determines that the amount of the bond... appropriate TTB officer may require the proprietor to file a strengthening bond in an appropriate amount with...

27 CFR 44.245 - Strengthening bond.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2013-04-01 2013-04-01 false Strengthening bond. 44.245....245 Strengthening bond. Where the appropriate TTB officer determines that the amount of the bond... appropriate TTB officer may require the proprietor to file a strengthening bond in an appropriate amount with...

27 CFR 44.245 - Strengthening bond.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Strengthening bond. 44.245....245 Strengthening bond. Where the appropriate TTB officer determines that the amount of the bond... appropriate TTB officer may require the proprietor to file a strengthening bond in an appropriate amount with...

48 CFR 245.201-73 - Security classification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Security classification... Procedures 245.201-73 Security classification. Follow the procedures at PGI 245.201-73 for security classification. ...

48 CFR 245.201-73 - Security classification.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Security classification... Procedures 245.201-73 Security classification. Follow the procedures at PGI 245.201-73 for security classification. ...

8 CFR 245a.19 - Interviews.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Interviews. 245a.19 Section 245a.19 Aliens... Interviews. (a) All aliens filing applications for adjustment of status with the Service under this section must be personally interviewed, except that the adjudicative interview may be waived for a child under...

48 CFR 245.7307 - Non-competitive sales.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Non-competitive sales. 245..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Sale of Surplus Contractor Inventory 245.7307 Non-competitive sales. ...

48 CFR 252.245-7003 - Contractor Property Management System Administration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Management System Administration. 252.245-7003 Section 252.245-7003 Federal Acquisition Regulations System... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.245-7003 Contractor Property Management System Administration. As prescribed in 245.107, insert the following clause: CONTRACTOR PROPERTY MANAGEMENT SYSTEM...

Effect of precipitation, geographical location and biosynthesis on New Zealand milk powder bulk and fatty acids D/H ratios

NASA Astrophysics Data System (ADS)

Frew, R.; Emad Ehtesham, R.; Van Hale, R.; Hayman, A.; Baisden, T.

2012-04-01

D/H ratio measurements provide useful information for the investigation of biogeochemical influences on natural and agricultural produce, particularly with application to food traceability and authentication. Numerous studies have shown that variation of a product's D/H ratio is influenced by both environmental factors and biological processes. This study investigates the D/H ratio of New Zealand milk powder and individual fatty acids, and causal determinants of isotopic variation. One of the key environmental factors is precipitation, and the D/H ratio "isoscaping" of NZ has been undertaken. New Zealand provides a unique geography for these kinds of study in terms of proximity to the ocean and natural geographical variability from sea level to elevations as high as 3700 m. Milk powder samples were collected from different geographical regions from milk processing units, which were supplied by producers in the immediate region. H/D ratios of bulk milk powder and of individual fatty acids were determined. Initial comparison of the precipitation and milk powder bulk D/H data show a very good differentiation from north to southernmost parts of New Zealand and a relation between rain and milk bulk D/H abundance ratio. Almost 98% of milk FAs are in the form of triglycerides that have been extracted and hydrolysed to free FAs. Free FAs were esterified and analyzed with GC-IRMS. Individual FAs show variation in D/H ratio, and all values are depleted relative to the precipitation data. The difference in D/H ratio amongst individual FAs reflects the geographical environment and biological processes i.e. micro-organisms activity in the rumen of the cow. Short chain FAs (less than 8 carbons), particularly C4 (Butyric acid), appear to be key determinants. The variation in the data can be rationalized using statistical multivariate analysis.

A HERSCHEL STUDY OF D/H IN WATER IN THE JUPITER-FAMILY COMET 45P/HONDA-MRKOS-PAJDUSAKOVA AND PROSPECTS FOR D/H MEASUREMENTS WITH CCAT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lis, D. C.; Blake, G. A.; Biver, N.

We present Herschel observations of water isotopologues in the atmosphere of the Jupiter-family comet 45P/Honda-Mrkos-Pajdusakova. No HDO emission is detected, with a 3{sigma} upper limit of 2.0 Multiplication-Sign 10{sup -4} for the D/H ratio. This value is consistent with the earlier Herschel measurement in the Jupiter-family comet 103P/Hartley 2. The canonical value of 3 Multiplication-Sign 10{sup -4} measured pre-Herschel in a sample of Oort-cloud comets can be excluded at a 4.5{sigma} level. The observations presented here further confirm that a diversity of D/H ratios exists in the comet population and emphasize the need for additional measurements with future ground-based facilities,more » such as CCAT, in the post-Herschel era.« less

42 CFR 24.5 - Peer review.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Peer review. 24.5 Section 24.5 Public Health PUBLIC....5 Peer review. An individual may not be considered for appointment into the SBRS unless his/her qualifications have been reviewed by a PHS peer review committee and the committee has recommended appointment to...

48 CFR 245.105 - Contractor's property management system compliance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... management system compliance. 245.105 Section 245.105 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY General 245.105 Contractor's property management system compliance. The assigned property administrator shall perform...

48 CFR 245.105 - Contractors' property management system compliance.

Code of Federal Regulations, 2011 CFR

2011-10-01

... management system compliance. 245.105 Section 245.105 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY General 245.105 Contractors' property management system compliance. (a) Definitions— (1) Acceptable property management system...

D/H Ratios From Sierra Nevada Varved Lake Sediments Record Decadal Hydroclimate Variability During The Medieval Period

NASA Astrophysics Data System (ADS)

Roach, L. D.; Cayan, D. R.; Sessions, A. L.; Charles, C. D.; Anderson, R. S.

2009-12-01

Assessment of the risks of persistent drought requires multiple realizations of decadal and centennial scale hydroclimate variability that extend beyond the relatively short period of instrumental record. Much remains to be learned about the so called “mega droughts” in the Sierra Nevada Mountains, where various lines of evidence point toward the occurrence of severe, decades-long droughts during Medieval times, approximately 900-1400 AD. Here we present a continuous, decadal scale record of hydroclimate variability in the Sierra Nevada Mountains that extends through the heart of the purported Medieval mega droughts. Previous work on the stable hydrogen isotope (D/H) ratios of refractory plant lipid compounds stored in lake sediments demonstrated that these compounds reflect the D/H values of lake water and/or shallow ground water--reservoirs both fed by local precipitation. Lake sediment D/H can therefore reflect the processes that determine D/H of precipitation, including temperature, humidity and moisture source. We have measured D/H of aquatic and terrestrial plant fatty acids extracted from a suite of sediment cores collected at Swamp Lake (elevation: 1554m), in Yosemite National Park, along the Sierra Nevada crest. Measurements with biennial resolution were made for two time periods: the 20th century and the 13th-15th centuries. D/H fluctuations in 20th century sediment contain relatively strong decadal structure. Comparison with instrumentally recorded climate variability reveals that lower D/H concentrations are associated with years of higher than normal annual precipitation, cooler than normal wintertime temperatures, and positive April 1 Snow Water Equivalent (SWE) anomalies throughout the Sierra Nevada, (and conversely for elevated D/H concentrations). The range of variability is approximately 50‰. These associations may be driven by the variable mass-balance impact of evaporation on the isotopic composition of lake water and shallow groundwater

The Imprint of Atmospheric Evolution in the D/H of Hesperian Clay Minerals on Mars

NASA Technical Reports Server (NTRS)

Mahaffy, P. R.; Webster, C. R.; Stern, J. C.; Brunner, A. E.; Atreya, S. K.; Conrad, P. G.; Domagal-Goldman, S.; Eigenbrode, J. L.; Flesch, G. J.; Christensen, L. E.;

48 CFR 245.7203 - Assigning plant clearance case numbers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Q—Navy E—Air Force L—Marine Corps U—Defense Logistics Agency N—Defense Nuclear Agency M—National... case numbers. 245.7203 Section 245.7203 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Special Instructions 245...

Extension of D-H parameter method to hybrid manipulators used in robot-assisted surgery.

PubMed

Singh, Amanpreet; Singla, Ashish; Soni, Sanjeev

2015-10-01

The main focus of this work is to extend the applicability of D-H parameter method to develop a kinematic model of a hybrid manipulator. A hybrid manipulator is a combination of open- and closed-loop chains and contains planar and spatial links. It has been found in the literature that D-H parameter method leads to ambiguities, when dealing with closed-loop chains. In this work, it has been observed that the D-H parameter method, when applied to a hybrid manipulator, results in an orientational inconsistency, because of which the method cannot be used to develop the kinematic model. In this article, the concept of dummy frames is proposed to resolve the orientational inconsistency and to develop the kinematic model of a hybrid manipulator. Moreover, the prototype of 7-degree-of-freedom hybrid manipulator, known as a surgeon-side manipulator to assist the surgeon during a medical surgery, is also developed to validate the kinematic model derived in this work. © IMechE 2015.

48 CFR 1852.245-71 - Installation-accountable Government property.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Government property. 1852.245-71 Section 1852.245-71 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.245-71 Installation-accountable Government property. As prescribed in 1845.107-70(b)(1), insert the following clause: Installation-Accountable Government Property (JAN 2011) (a) The...

48 CFR 1852.245-71 - Installation-accountable Government property.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Government property. 1852.245-71 Section 1852.245-71 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.245-71 Installation-accountable Government property. As prescribed in 1845.107-70(b)(1), insert the following clause: Installation-Accountable Government Property (JAN 2011) (a) The...

48 CFR 1852.245-80 - Government property management information.

Code of Federal Regulations, 2014 CFR

2014-10-01

... management information. 1852.245-80 Section 1852.245-80 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.245-80 Government property management information. As prescribed in 1845.107-70(k)(1), insert the following provision. Government Property Management Information (JAN 2011) (a) The...

48 CFR 1852.245-80 - Government property management information.

Code of Federal Regulations, 2012 CFR

2012-10-01

... management information. 1852.245-80 Section 1852.245-80 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.245-80 Government property management information. As prescribed in 1845.107-70(k)(1), insert the following provision. Government Property Management Information (JAN 2011) (a) The...

Participation of PLA2 and PLC in DhL-induced activation of Rhinella arenarum oocytes.

PubMed

Zapata-Martínez, J; Medina, M F; Gramajo-Bühler, M C; Sánchez-Toranzo, G

2016-08-01

Rhinella arenarum oocytes can be artificially activated, a process known as parthenogenesis, by a sesquiterpenic lactone of the guaianolide group, dehydroleucodine (DhL). Transient increases in the concentration of cytosolic Ca2+ are essential to trigger egg activation events. In this sense, the 1-4-5 inositol triphosphate receptors (IP3R) seem to be involved in the Ca2+ transient release induced by DhL in this species. We analyzed the involvement of phosphoinositide metabolism, especially the participation of phospholipase A2 (PLA2) and phospholipase C (PLC) in DhL-induced activation. Different doses of quinacrine, aristolochic acid (ATA) (PLA2 inhibitors) or neomycin, an antibiotic that binds to PIP2, thus preventing its hydrolysis, were used in mature Rhinella arenarum oocytes. In order to assay the participation of PI-PLC and PC- PLC we used U73122, a competitive inhibitor of PI-PLC dependent events and D609, an inhibitor of PC-PLC. We found that PLA2 inhibits quinacrine more effectively than ATA. This difference could be explained by the fact that quinacrine is not a specific inhibitor for PLA2 while ATA is specific for this enzyme. With respect to the participation of PLC, a higher decrease in oocyte activation was detected when cells were exposed to neomycin. Inhibition of PC-PLC with D609 and IP-PLC with U73122 indicated that the last PLC has a significant participation in the effect of DhL-induced activation. Results would indicate that DhL induces activation of in vitro matured oocytes of Rhinella arenarum by activation of IP-PLC, which in turn may induce IP3 formation which produces Ca2+ release.

48 CFR 1552.245-70 - Government property.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Government property. 1552.245-70 Section 1552.245-70 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY... the Federal Acquisition Regulation (FAR). 2. Contract Property Administration (CPAR) a. EPA Delegation...

50 CFR 600.245 - Council member compensation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false Council member compensation. 600.245 Section 600.245 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Council Membership § 600...

48 CFR 245.7303 - Formal bid procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

....7303 Section 245.7303 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Sale of Surplus Contractor Inventory 245.7303... appropriate trade journals or magazines and local newspapers. (e) When the acquisition cost of the property to...

Evidence for Primordial Water in Earths Deep Mantle: D/h Ratios in Baffin Island and Icelandic Picrites

NASA Astrophysics Data System (ADS)

Hallis, L. J.; Huss, G. R.; Nagashima, K.; Taylor, J.; Hilton, D. R.; Mottl, M. J.; Meech, K. J.; Halldorsson, S. A.

2016-12-01

Experimentally based chemical models suggest Jeans escape could have caused an increase in Earth's atmospheric D/H ratio of between a factor of 2 and 9 since the planets formation1. Plate tectonic mixing ensures this change has been incorporated into the mantle. In addition, collisions with hydrogen bearing planetesimals or cometary material after Earth's accretion could have altered the D/H ratio of the planet's surface and upper mantle2. Therefore, to determine Earth's original D/H ratio, a reservoir that has been completely unaffected by these surface and upper mantle changes is required. Most studies suggest that high 3He/4He ratios in some OIBs indicate the existence of relatively undegassed regions in the deep mantle compared to the upper mantle, which retain a greater proportion of their primordial He3-4. Early Tertiary (60-million-year-old) picrites from Baffin Island and west Greenland, which represent volcanic rocks from the proto/early Iceland mantle plume, contain the highest recorded terrestrial 3He/4He ratios3-4. These picrites also have Pb and Nd isotopic ratios consistent with primordial mantle ages (4.45 to 4.55 Ga)5, indicating the persistence of an ancient, isolated reservoir in the mantle. The undegassed and primitive nature6of this reservoir suggests that it could preserve Earth's initial D/H ratio. We measured the D/H ratios of olivine-hosted glassy melt inclusions in Baffin Island and Icelandic picrites to establish whether their deep mantle source region exhibits a different D/H ratio to known upper mantle and surface reservoirs. Baffin Island D/H ratios were found to extend lower than any previously measured mantle values (δD -97 to -218 ‰), suggesting that areas of the deep mantle do preserve a more primitive hydrogen reservoir, hence are unaffected by plate tectonic mixing. Comparing our measured low D/H ratios to those of known extra-terrestrial materials can help determine where Earths water came from. References: [1] Genda and Ikoma

Formation Location of Enceladus and Comets from D/H Measurements

NASA Astrophysics Data System (ADS)

Petit, J.-M.; Mousis, O.; Kavelaars, J. J.

2012-04-01

The building blocks of Enceladus could have formed in Saturn's subnebula, thus bearing no connection with planetesimals condensed in Saturn's feeding zone. We have shown that the D/H ratio in H2O in Saturn's sub-nebula reaches the protosolar value in about 1,000 yr, well before ice forms again at Enceladus' location (several 10,000 yr). However, the D/H ratio measured by the Ion and Neutral Mass Spectrometer aboard the Cassini spacecraft in Saturn's satellite Enceladus is remarkably similar to the values observed in the nearly-isotropic comets. Hence the building blocks of Enceladus formed in the solar nebula. Nearly-isotropic comets originate from the Oort cloud. Delivery of material into the Oort cloud reservoir is controlled by Uranus-Neptune scattering. The D/H ratio in comets is therefore representative of that of the location of Uranus-Neptune at the time of formation of the Oort cloud. Since D/H strongly depends on heliocentric distance in the solar nebula, the similarity of D/H ratios links the primordial source region of the nearly-isotropic comets with the formation location of Enceladus. This precludes these comets from having formed beyond ~15 AU from the Sun. which in turn implies that Uranus and Neptune were originally closer to Saturn's location during the feeding of the Oort cloud, likely in the 12-15 AU region. Such a configuration is consistent with the Nice model of evolution of the outer Solar System. 103P/Hartley 2 being D-poor compared to these bodies questions the current models. A fraction of ecliptic comets could have formed at closer distances from the Sun than assumed here and has been ejected outward and then display a low R/H ratio. However, they would only represent a small fraction of all ecliptic comets. The high level of deuteration predicted in ecliptic comets from the description of the isotopic exchange between H2 and H2O in the gas phase of the disk is based on classical models of the solar nebula (the alpha-turbulent model) in

33 CFR 245.20 - Determination of hazard to navigation.

Code of Federal Regulations, 2012 CFR

2012-07-01

... navigation. 245.20 Section 245.20 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.20 Determination of hazard to navigation... weather conditions. (9) Length of time the obstruction has been in existence. (10) History of vessel...

33 CFR 245.20 - Determination of hazard to navigation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... navigation. 245.20 Section 245.20 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.20 Determination of hazard to navigation... weather conditions. (9) Length of time the obstruction has been in existence. (10) History of vessel...

33 CFR 245.20 - Determination of hazard to navigation.

Code of Federal Regulations, 2013 CFR

2013-07-01

... navigation. 245.20 Section 245.20 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.20 Determination of hazard to navigation... weather conditions. (9) Length of time the obstruction has been in existence. (10) History of vessel...

33 CFR 245.20 - Determination of hazard to navigation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... navigation. 245.20 Section 245.20 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.20 Determination of hazard to navigation... weather conditions. (9) Length of time the obstruction has been in existence. (10) History of vessel...

33 CFR 245.20 - Determination of hazard to navigation.

Code of Federal Regulations, 2014 CFR

2014-07-01

... navigation. 245.20 Section 245.20 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.20 Determination of hazard to navigation... weather conditions. (9) Length of time the obstruction has been in existence. (10) History of vessel...

27 CFR 28.245 - Shipment to foreign-trade zone.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Shipment to foreign-trade zone. 28.245 Section 28.245 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Consignment § 28.245 Shipment to foreign-trade zone. Where distilled spirits (including specially denatured...

27 CFR 28.245 - Shipment to foreign-trade zone.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Shipment to foreign-trade zone. 28.245 Section 28.245 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Consignment § 28.245 Shipment to foreign-trade zone. Where distilled spirits (including specially denatured...

27 CFR 28.245 - Shipment to foreign-trade zone.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Shipment to foreign-trade zone. 28.245 Section 28.245 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Consignment § 28.245 Shipment to foreign-trade zone. Where distilled spirits (including specially denatured...

27 CFR 28.245 - Shipment to foreign-trade zone.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Shipment to foreign-trade zone. 28.245 Section 28.245 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Consignment § 28.245 Shipment to foreign-trade zone. Where distilled spirits (including specially denatured...

14 CFR 21.245 - Maintenance of eligibility.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Maintenance of eligibility. 21.245 Section 21.245 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... requirements for issue of the authorization or shall notify the Administrator within 48 hours of any change...

14 CFR 21.245 - Maintenance of eligibility.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Maintenance of eligibility. 21.245 Section 21.245 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... requirements for issue of the authorization or shall notify the Administrator within 48 hours of any change...

27 CFR 46.245 - Errors in records.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Errors in records. 46.245 Section 46.245 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MISCELLANEOUS REGULATIONS RELATING TO TOBACCO PRODUCTS AND...

27 CFR 46.245 - Errors in records.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Errors in records. 46.245 Section 46.245 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MISCELLANEOUS REGULATIONS RELATING TO TOBACCO PRODUCTS AND...

Impaired Insulin Signaling is Associated with Hepatic Mitochondrial Dysfunction in IR+/--IRS-1+/- Double Heterozygous (IR-IRS1dh) Mice.

PubMed

Franko, Andras; Kunze, Alexander; Böse, Marlen; von Kleist-Retzow, Jürgen-Christoph; Paulsson, Mats; Hartmann, Ursula; Wiesner, Rudolf J

2017-05-30

Mitochondria play a pivotal role in energy metabolism, but whether insulin signaling per se could regulate mitochondrial function has not been identified yet. To investigate whether mitochondrial function is regulated by insulin signaling, we analyzed muscle and liver of insulin receptor (IR) +/- -insulin receptor substrate-1 (IRS-1) +/- double heterozygous (IR-IRS1dh) mice, a well described model for insulin resistance. IR-IRS1dh mice were studied at the age of 6 and 12 months and glucose metabolism was determined by glucose and insulin tolerance tests. Mitochondrial enzyme activities, oxygen consumption, and membrane potential were assessed using spectrophotometric, respirometric, and proton motive force analysis, respectively. IR-IRS1dh mice showed elevated serum insulin levels. Hepatic mitochondrial oxygen consumption was reduced in IR-IRS1dh animals at 12 months of age. Furthermore, 6-month-old IR-IRS1dh mice demonstrated enhanced mitochondrial respiration in skeletal muscle, but a tendency of impaired glucose tolerance. On the other hand, 12-month-old IR-IRS1dh mice showed improved glucose tolerance, but normal muscle mitochondrial function. Our data revealed that deficiency in IR/IRS-1 resulted in normal or even elevated skeletal muscle, but impaired hepatic mitochondrial function, suggesting a direct cross-talk between insulin signaling and mitochondria in the liver.

33 CFR 245.50 - Removal by Corps of Engineers.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Removal by Corps of Engineers. 245.50 Section 245.50 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.50 Removal by Corps of Engineers. (a...

33 CFR 245.50 - Removal by Corps of Engineers.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Removal by Corps of Engineers. 245.50 Section 245.50 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.50 Removal by Corps of Engineers. (a...

33 CFR 245.50 - Removal by Corps of Engineers.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Removal by Corps of Engineers. 245.50 Section 245.50 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.50 Removal by Corps of Engineers. (a...

33 CFR 245.50 - Removal by Corps of Engineers.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Removal by Corps of Engineers. 245.50 Section 245.50 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.50 Removal by Corps of Engineers. (a...

33 CFR 245.50 - Removal by Corps of Engineers.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Removal by Corps of Engineers. 245.50 Section 245.50 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.50 Removal by Corps of Engineers. (a...

48 CFR 245.7310-2 - Performance bond.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Performance bond. 245.7310..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Sale of Surplus Contractor Inventory 245.7310-2 Performance bond. Performance bonds are required when work, other than loading, is to be performed by the...

48 CFR 245.201-71 - Security classification.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Security classification... Procedures 245.201-71 Security classification. Follow the procedures at PGI 245.201-71 for security classification. [76 FR 3537, Jan. 20, 2011. Redesignated and amended at 77 FR 76937, Dec. 31, 2012] ...

48 CFR 245.201-71 - Security classification.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Security classification... Procedures 245.201-71 Security classification. Follow the procedures at PGI 245.201-71 for security classification. [76 FR 3537, Jan. 20, 2011. Redesignated and amended at 77 FR 76937, Dec. 31, 2012] ...

24 CFR 990.245 - Types of appeals.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Types of appeals. 990.245 Section... THE PUBLIC HOUSING OPERATING FUND PROGRAM Appeals § 990.245 Types of appeals. (a) Streamlined appeal. This appeal would demonstrate that the application of a specific Operating Fund formula component has a...

Mars atmospheric D/H - Consistent with polar volatile theory?

NASA Technical Reports Server (NTRS)

Jakosky, Bruce M.

1990-01-01

Current theories on the Martian water history are discussed on the basis of data for the D/H ratio in the Martian atmosphere (which was found to be enhanced by a factor of 6 + or - relative to the value on earth). In particular, the calculations of Yung et al. (1988), on the basis of their photochemical model, are found to be inconsistent with current theories for the evolution of the polar deposits on Mars. While the photochemical model predicts that about 95 percent of the Martian water has escaped over geologic time and the nonatmospheric reservoir is now only 02 m thick, the polar volatile theory suggest that polar deposits contain the equivalent of tens of meters of water, requiring a more rapid escape of H and D to space than predicted by the photochemical model to match the observed D/H ratio. The paper examines the behavior of the polar caps and the atmospheric water vapor over geologic time and the loss of H and D to space. It is concluded that, at present, it is premature to accept a specific history for water on Mars.

48 CFR 245.7311-2 - Safety, security, and fire regulations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Safety, security, and fire regulations. 245.7311-2 Section 245.7311-2 Federal Acquisition Regulations System DEFENSE ACQUISITION... Inventory 245.7311-2 Safety, security, and fire regulations. ...

48 CFR 245.602-70 - Plant clearance procedures.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Plant clearance procedures... Disposal 245.602-70 Plant clearance procedures. Follow the procedures at PGI 245.602-70 for establishing and processing a plant clearance case. ...

48 CFR 245.602-70 - Plant clearance procedures.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Plant clearance procedures... Disposal 245.602-70 Plant clearance procedures. Follow the procedures at PGI 245.602-70 for establishing and processing a plant clearance case. ...

48 CFR 245.602-70 - Plant clearance procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Plant clearance procedures... Disposal 245.602-70 Plant clearance procedures. Follow the procedures at PGI 245.602-70 for establishing and processing a plant clearance case. ...

48 CFR 245.602-70 - Plant clearance procedures.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Plant clearance procedures... Disposal 245.602-70 Plant clearance procedures. Follow the procedures at PGI 245.602-70 for establishing and processing a plant clearance case. ...

48 CFR 245.7310-3 - Liability and insurance.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... 245.7310-3 Section 245.7310-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Sale of Surplus Contractor... this requirement upon receipt of satisfactory evidence that the Purchaser is qualified as a self...

48 CFR 1852.245-79 - Use of Government-owned property.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-owned facilities (real property or plant equipment), special test equipment, or special tooling... property. 1852.245-79 Section 1852.245-79 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... and Clauses 1852.245-79 Use of Government-owned property. As prescribed in 1845.106-70(i), insert the...

Cytoskeletal perturbation induced by herbicides, 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T).

PubMed

Zhao, Y; Li, W; Chou, I N

1987-01-01

To understand the mechanisms of toxicity of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), we have studied their effects on the cytoskeletal organization, particularly microtubules (MT) and microfilaments (MF), DNA synthesis, and the synthesis and composition of cytoskeletal proteins in mouse 3T3 cells. Exposure of cells to 2,4-D or 2,4,5-T resulted in a dose-dependent inhibition of DNA synthesis; 50% inhibition occurred at 2.21 mM and 0.90 mM for 2,4-D and 2,4,5-T, respectively. Furthermore, a strong synergistic inhibition of DNA synthesis was produced by mixtures (each having a total concentration of 1.25 mM) of 2,4-D with 2,4,5-T. Similarly, 2,4,5-T is more potent than 2,4-D in causing cytoskeletal perturbation as revealed by fluorescence microscopy. Treatment of cells with 2,4-D (2.5 mM) or 2,4,5-T (1.25 mM) for 20 h resulted in severe MT aggregation and the appearance of large bundles, which were organized in a rope-like structure in the former and a dramatic octopus-like pattern in the latter. Further, MT bundling is particularly severe in the cell center. Under these conditions, marked changes in MF organization also occurred as evidenced by clustering and crisscrossing of MF in the perinuclear region. A 1:1 mixture (final = 1.25 mM) of 2,4-D and 2,4,5-T, a formulation equivalent to Agent Orange composition, also induced a dramatic perturbation to the organization of MT and MF, resulting in the formation of ring-like structures. MT bundling is still apparent, especially around the outer edge of the "rings." MF are localized predominantly along the cell periphery, where they appear to be aggregated tightly forming patches. Surprisingly, the synthesis and composition of cytoskeletal proteins, which are resistant to detergent extraction but released by CaCl2, are essentially unaffected by 2,4-D or 2,4,5-T. These results suggest that the dramatic perturbation of the cytoskeletal morphology caused by these herbicides

Overexpression of Salmonella enterica serovar Typhi recA gene confers fluoroquinolone resistance in Escherichia coli DH5α.

PubMed

Yassien, M A M; Elfaky, M A

2015-11-01

A spontaneous fluoroquinolone-resistant mutant (STM1) was isolated from its parent Salmonella enterica serovar Typhi (S. Typhi) clinical isolate. Unlike its parent isolate, this mutant has selective resistance to fluoroquinolones without any change in its sensitivity to various other antibiotics. DNA gyrase assays revealed that the fluoroquinolone resistance phenotype of the STM1 mutant did not result from alteration of the fluoroquinolone sensitivity of the DNA gyrase isolated from it. To study the mechanism of fluoroquinolone resistance, a genomic library from the STM1 mutant was constructed in Escherichia coli DH5α and two recombinant plasmids were obtained. Only one of these plasmids (STM1-A) conferred the selective fluoroquinolone resistance phenotype to E. coli DH5α. The chromosomal insert from STM1-A, digested with EcoRI and HindIII restriction endonucleases, produced two DNA fragments and these were cloned separately into pUC19 thereby generating two new plasmids, STM1-A1 and STM1-A2. Only STM1-A1 conferred the selective fluoroquinolone resistance phenotype to E. coli DH5α. Sequence and subcloning analyses of STM1-A1 showed the presence of an intact RecA open reading frame. Unlike that of the wild-type E. coli DH5α, protein analysis of a crude STM1-A1 extract showed overexpression of a 40 kDa protein. Western blotting confirmed the 40 kDa protein band to be RecA. When a RecA PCR product was cloned into pGEM-T and introduced into E. coli DH5α, the STM1-A11 subclone retained fluoroquinolone resistance. These results suggest that overexpression of RecA causes selective fluoroquinolone resistance in E. coli DH5α.

Mars atmosphere. The imprint of atmospheric evolution in the D/H of Hesperian clay minerals on Mars.

PubMed

Mahaffy, P R; Webster, C R; Stern, J C; Brunner, A E; Atreya, S K; Conrad, P G; Domagal-Goldman, S; Eigenbrode, J L; Flesch, G J; Christensen, L E; Franz, H B; Freissinet, C; Glavin, D P; Grotzinger, J P; Jones, J H; Leshin, L A; Malespin, C; McAdam, A C; Ming, D W; Navarro-Gonzalez, R; Niles, P B; Owen, T; Pavlov, A A; Steele, A; Trainer, M G; Williford, K H; Wray, J J

2015-01-23

The deuterium-to-hydrogen (D/H) ratio in strongly bound water or hydroxyl groups in ancient martian clays retains the imprint of the water of formation of these minerals. Curiosity's Sample Analysis at Mars (SAM) experiment measured thermally evolved water and hydrogen gas released between 550° and 950°C from samples of Hesperian-era Gale crater smectite to determine this isotope ratio. The D/H value is 3.0 (±0.2) times the ratio in standard mean ocean water. The D/H ratio in this ~3-billion-year-old mudstone, which is half that of the present martian atmosphere but substantially higher than that expected in very early Mars, indicates an extended history of hydrogen escape and desiccation of the planet. Copyright © 2015, American Association for the Advancement of Science.

29 CFR 1952.245 - Where the plan may be inspected.

Code of Federal Regulations, 2010 CFR

2010-07-01

... and copied during normal business hours at the following locations: Office of State Programs... 29 Labor 9 2010-07-01 2010-07-01 false Where the plan may be inspected. 1952.245 Section 1952.245..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Alaska § 1952.245...

A massive hydrogen-rich Martian greenhouse recorded in D/H

NASA Astrophysics Data System (ADS)

Pahlevan, K.; Schaefer, L. K.; Desch, S. J.; Elkins-Tanton, L. T.

2017-12-01

The deuterium-to-hydrogen (D/H) ratio in Martian atmospheric water ( 6x standard mean ocean water, SMOW) [1,2] is higher than that of known sources [3,4] alluding to a planetary enrichment process. A recent measurement by the Curiosity rover of Hesperian clays yields a D/H value 3x higher than SMOW [5], demonstrating that most enrichment occurred early in planetary history, buttressing the conclusions of Martian meteorite studies [6,7]. Extant models of the isotopic evolution of the Martian hydrosphere have not incorporated primordial H2, despite its likely abundance on early Mars. Here, we report the first 1D climate calculations with an atmospheric composition determined via degassing from a reducing magma ocean to study Martian climate during an early water ocean stage. A reducing Martian magma ocean is expected based on experimental petrology [8], the degassing of which gives rise to an H2-rich steam atmosphere [9] with strong attendant greenhouse warming [10,11] even after the removal of steam via condensation. At the pressures and temperatures prevailing in such a degassed greenhouse, we find that isotopic exchange in the fluid envelope is rapid, strongly concentrating deuterium in water molecules over molecular hydrogen [12]. The subsequent loss of the isotopically light H2-rich atmosphere results in a 2x D/H enrichment in the oceans via isotopic equilibration alone. These calculations suggest that most of the D/H enrichment observed in the first billion years of Martian history is produced by the evolution of a massive ( 100 bar) H2-rich greenhouse in the aftermath of magma ocean crystallization. The proposed link between early planetary process and modern isotopic observable opens a new window into the earliest history of Mars. [1] Owen, T. et al. Science 240, 1767-1770 (1988). [2] Webster, C. R. et al. Science 341, 260-263 (2013). [3] Lunine, J. I. et al. Icarus 165, 1-8, (2003). [4] Marty, B. et al. EPSL 441, 91-102, (2016). [5] Mahaffy, P. et al

[Selection of acetate-tolerant mutants from Escherichia coli DH5alpha and the metabolic properties of mutant DA19].

PubMed

Zhu, Caiqing; Ye, Qin

2003-08-01

Esherichia coli DH5alpha is one of the widely used host strains in genetic engineering. However, foreign gene expression level in this strain is seriously inhibited due to its great sensitivity to the accumulated metabolite, acetate. This study aimed at improving the tolerance of this strain against acetate. Cells of E. coli DH5alpha were irradiated with 60Co, and subsequently continuous culture of the irradiated cells was conducted with gradual increase in the dilution rate and the selective pressure, acetate concentration in the medium. The mutants were picked up on MA plates which contained 5g/L sodium acetate. 5 strains with great improvement in acetate tolerance were obtained, among which DA19 was the best. In cultivation of DA19 in complex media YPS and YPS2G, the cell density, maximum specific growth rate and acetate produced were respectively 1.17 and 1.05, 1.08 and 1.27, and 0.06 and 0.59 times of those of DH5alpha. In a chemically defined medium, the cell density of DA19 was 3.4-fold of that of DH5alpha. The cell density of DA19 in a medium containing 10g/L sodium acetate was comparable to that of DH5alpha in the same medium without the addition of acetate.

A Herschel Study of D/H in Water in the Jupiter-family Comet 45P/Honda-Mrkos-Pajdušáková and Prospects for D/H Measurements with CCAT

NASA Astrophysics Data System (ADS)

Lis, D. C.; Biver, N.; Bockelée-Morvan, D.; Hartogh, P.; Bergin, E. A.; Blake, G. A.; Crovisier, J.; de Val-Borro, M.; Jehin, E.; Küppers, M.; Manfroid, J.; Moreno, R.; Rengel, M.; Szutowicz, S.

2013-09-01

We present Herschel observations of water isotopologues in the atmosphere of the Jupiter-family comet 45P/Honda-Mrkos-Pajdušáková. No HDO emission is detected, with a 3σ upper limit of 2.0 × 10-4 for the D/H ratio. This value is consistent with the earlier Herschel measurement in the Jupiter-family comet 103P/Hartley 2. The canonical value of 3 × 10-4 measured pre-Herschel in a sample of Oort-cloud comets can be excluded at a 4.5σ level. The observations presented here further confirm that a diversity of D/H ratios exists in the comet population and emphasize the need for additional measurements with future ground-based facilities, such as CCAT, in the post-Herschel era.

Cometary science. 67P/Churyumov-Gerasimenko, a Jupiter family comet with a high D/H ratio.

PubMed

Altwegg, K; Balsiger, H; Bar-Nun, A; Berthelier, J J; Bieler, A; Bochsler, P; Briois, C; Calmonte, U; Combi, M; De Keyser, J; Eberhardt, P; Fiethe, B; Fuselier, S; Gasc, S; Gombosi, T I; Hansen, K C; Hässig, M; Jäckel, A; Kopp, E; Korth, A; LeRoy, L; Mall, U; Marty, B; Mousis, O; Neefs, E; Owen, T; Rème, H; Rubin, M; Sémon, T; Tzou, C-Y; Waite, H; Wurz, P

2015-01-23

The provenance of water and organic compounds on Earth and other terrestrial planets has been discussed for a long time without reaching a consensus. One of the best means to distinguish between different scenarios is by determining the deuterium-to-hydrogen (D/H) ratios in the reservoirs for comets and Earth's oceans. Here, we report the direct in situ measurement of the D/H ratio in the Jupiter family comet 67P/Churyumov-Gerasimenko by the ROSINA mass spectrometer aboard the European Space Agency's Rosetta spacecraft, which is found to be (5.3 ± 0.7) × 10(-4)—that is, approximately three times the terrestrial value. Previous cometary measurements and our new finding suggest a wide range of D/H ratios in the water within Jupiter family objects and preclude the idea that this reservoir is solely composed of Earth ocean-like water. Copyright © 2015, American Association for the Advancement of Science.

15 CFR 904.245 - Subpoenas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS CIVIL PROCEDURES Hearing and Appeal Procedures Discovery § 904.245 Subpoenas. (a) In general. Subpoenas for the attendance and...

15 CFR 904.245 - Subpoenas.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS CIVIL PROCEDURES Hearing and Appeal Procedures Discovery § 904.245 Subpoenas. (a) In general. Subpoenas for the attendance and...

2 CFR 1401.245 - Federal agency or agency.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Federal agency or agency. 1401.245 Section 1401.245 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF THE INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) (Eff. 1-21-2011) Definitions § 1401...

Modelling of Technological Solutions to 4th Generation DH Systems

NASA Astrophysics Data System (ADS)

Vigants, Edgars; Prodanuks, Toms; Vigants, Girts; Veidenbergs, Ivars; Blumberga, Dagnija

2017-11-01

Flue gas evaporation and condensing processes are investigated in a direct contact heat exchanger - condensing unit, which is installed after a furnace. By using equations describing processes of heat and mass transfer, as well as correlation coherences for determining wet gas parameters, a model is formed to create a no-filling, direct contact heat exchanger. Results of heating equipment modelling and experimental research on the gas condensing unit show, that the capacity of the heat exchanger increases, when return temperature of the district heating network decreases. In order to explain these alterations in capacity, the character of the changes in water vapour partial pressure, in the propelling force of mass transfer, in gas and water temperatures and in the determining parameters of heat transfer are used in this article. The positive impact on the direct contact heat exchanger by the decreased district heating (DH) network return temperature shows that introduction of the 4th generation DH system increases the energy efficiency of the heat exchanger. In order to make an assessment, the methodology suggested in the paper can be used in each particular situation.

2,4,5-Trichlorophenol

Integrated Risk Information System (IRIS)

2,4,5 - Trichlorophenol ; CASRN 95 - 95 - 4 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcino

48 CFR 245.102 - Policy.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 245.102-70.) (1) Mapping, charting, and geodesy property. All Government-furnished mapping, charting, and geodesy (MC&G) property is under the control of the Director, National Geospatial Intelligence...

48 CFR 245.102 - Policy.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 245.102-70.) (1) Mapping, charting, and geodesy property. All Government-furnished mapping, charting, and geodesy (MC&G) property is under the control of the Director, National Geospatial Intelligence...

48 CFR 245.102 - Policy.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 245.102-70.) (1) Mapping, charting, and geodesy property. All Government-furnished mapping, charting, and geodesy (MC&G) property is under the control of the Director, National Geospatial Intelligence...

48 CFR 245.610-3 - Proceeds of sale.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Proceeds of sale. 245.610... Contractor Inventory 245.610-3 Proceeds of sale. (1) Unless otherwise provided in the contract, the proceeds of any sale, purchase, or retention shall be— (i) Credited to the Government as part of the...

48 CFR 245.7302-4 - Basis for sale.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Basis for sale. 245.7302-4..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Sale of Surplus Contractor Inventory 245.7302-4 Basis for sale. (a) Unit price basis—requires the offeror to state the bid price in terms of the...

14 CFR 135.245 - Second in command qualifications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Second in command qualifications. 135.245... Crewmember Requirements § 135.245 Second in command qualifications. (a) Except as provided in paragraph (b), no certificate holder may use any person, nor may any person serve, as second in command of an...

14 CFR 135.245 - Second in command qualifications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Second in command qualifications. 135.245... Crewmember Requirements § 135.245 Second in command qualifications. (a) Except as provided in paragraph (b), no certificate holder may use any person, nor may any person serve, as second in command of an...

14 CFR 135.245 - Second in command qualifications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Second in command qualifications. 135.245... Crewmember Requirements § 135.245 Second in command qualifications. (a) Except as provided in paragraph (b), no certificate holder may use any person, nor may any person serve, as second in command of an...

14 CFR 135.245 - Second in command qualifications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Second in command qualifications. 135.245... Crewmember Requirements § 135.245 Second in command qualifications. (a) Except as provided in paragraph (b), no certificate holder may use any person, nor may any person serve, as second in command of an...

14 CFR 135.245 - Second in command qualifications.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Second in command qualifications. 135.245... Crewmember Requirements § 135.245 Second in command qualifications. (a) Except as provided in paragraph (b), no certificate holder may use any person, nor may any person serve, as second in command of an...

48 CFR 245.102 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY General 245.102 Policy. (1) Mapping, charting, and geodesy property. All Government-furnished mapping, charting, and geodesy (MC&G) property is under the control of...

32 CFR 245.3 - Responsibilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... PLAN FOR THE EMERGENCY SECURITY CONTROL OF AIR TRAFFIC (ESCAT) General § 245.3 Responsibilities. The Assistant Secretary of Defense for Networks and Information Integration will ensure the responsibilities of...

32 CFR 245.3 - Responsibilities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... PLAN FOR THE EMERGENCY SECURITY CONTROL OF AIR TRAFFIC (ESCAT) General § 245.3 Responsibilities. The Assistant Secretary of Defense for Networks and Information Integration will ensure the responsibilities of...

32 CFR 245.3 - Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... PLAN FOR THE EMERGENCY SECURITY CONTROL OF AIR TRAFFIC (ESCAT) General § 245.3 Responsibilities. The Assistant Secretary of Defense for Networks and Information Integration will ensure the responsibilities of...

32 CFR 245.3 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... PLAN FOR THE EMERGENCY SECURITY CONTROL OF AIR TRAFFIC (ESCAT) General § 245.3 Responsibilities. The Assistant Secretary of Defense for Networks and Information Integration will ensure the responsibilities of...

Passage-dependent morphological and phenotypical changes of a canine histiocytic sarcoma cell line (DH82 cells).

PubMed

Heinrich, Franziska; Contioso, Vanessa Bono; Stein, Veronika M; Carlson, Regina; Tipold, Andrea; Ulrich, Reiner; Puff, Christina; Baumgärtner, Wolfgang; Spitzbarth, Ingo

2015-01-15

DH82 cells represent a permanent macrophage cell line isolated from a dog with histiocytic sarcoma (HS) and are commonly used in various fields of research upon infection and cancer, respectively. Despite its frequent use, data on cell surface antigen expression of this cell line are fragmentary and in part inconsistent. We therefore aimed at a detailed morphological and antigenic characterization of DH82 cells with respect to passage-dependent differences. Cellular morphology of early (≤ 13) and late (≥ 66) passages of DH82 cells was evaluated via scanning electron microscopy. Moreover, cells were labelled with 10 monoclonal antibodies directed against CD11c, CD14, CD18, CD44, CD45, CD80, CD86, MHC-I, MHC-II, and ICAM-1 for flow cytometric analysis. Early passage cells were characterized by round cell bodies with abundant small cytoplasmic projections whereas later passages exhibited a spindle-shaped morphology with large processes. The percentage of CD11c-, CD14-, CD18-, CD45-, and CD80 positive cells significantly decreased in late passages whereas the expression of CD44, CD86, MHC-I, MHC-II and ICAM-1 remained unchanged. DH82 cells represent a remarkably heterogeneous cell line with divergent antigenic and morphologic properties. The present findings have important implications for future studies, which should consider distinct characteristics with regard to the used passage. Copyright © 2014 Elsevier B.V. All rights reserved.

Impaired Insulin Signaling is Associated with Hepatic Mitochondrial Dysfunction in IR+/−-IRS-1+/− Double Heterozygous (IR-IRS1dh) Mice

PubMed Central

Franko, Andras; Kunze, Alexander; Böse, Marlen; von Kleist-Retzow, Jürgen-Christoph; Paulsson, Mats; Hartmann, Ursula; Wiesner, Rudolf J.

2017-01-01

Mitochondria play a pivotal role in energy metabolism, but whether insulin signaling per se could regulate mitochondrial function has not been identified yet. To investigate whether mitochondrial function is regulated by insulin signaling, we analyzed muscle and liver of insulin receptor (IR)+/−-insulin receptor substrate-1 (IRS-1)+/− double heterozygous (IR-IRS1dh) mice, a well described model for insulin resistance. IR-IRS1dh mice were studied at the age of 6 and 12 months and glucose metabolism was determined by glucose and insulin tolerance tests. Mitochondrial enzyme activities, oxygen consumption, and membrane potential were assessed using spectrophotometric, respirometric, and proton motive force analysis, respectively. IR-IRS1dh mice showed elevated serum insulin levels. Hepatic mitochondrial oxygen consumption was reduced in IR-IRS1dh animals at 12 months of age. Furthermore, 6-month-old IR-IRS1dh mice demonstrated enhanced mitochondrial respiration in skeletal muscle, but a tendency of impaired glucose tolerance. On the other hand, 12-month-old IR-IRS1dh mice showed improved glucose tolerance, but normal muscle mitochondrial function. Our data revealed that deficiency in IR/IRS-1 resulted in normal or even elevated skeletal muscle, but impaired hepatic mitochondrial function, suggesting a direct cross-talk between insulin signaling and mitochondria in the liver. PMID:28556799

26 CFR 1.245-1 - Dividends received from certain foreign corporations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... corporations. 1.245-1 Section 1.245-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Special Deductions for Corporations § 1.245-1 Dividends received from certain foreign corporations. (a) General rule. (1) A corporation is allowed a deduction...

8 CFR 245a.11 - Eligibility to adjust to LPR status.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Eligibility to adjust to LPR status. 245a.11 Section 245a.11 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS... 245A OF THE IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization...

8 CFR 245a.11 - Eligibility to adjust to LPR status.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Eligibility to adjust to LPR status. 245a.11 Section 245a.11 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS... 245A OF THE IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization...

8 CFR 245a.11 - Eligibility to adjust to LPR status.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Eligibility to adjust to LPR status. 245a.11 Section 245a.11 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS... SECTION 245A OF THE IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act...

8 CFR 245a.11 - Eligibility to adjust to LPR status.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Eligibility to adjust to LPR status. 245a.11 Section 245a.11 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS... 245A OF THE IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization...

48 CFR 252.245-7004 - Reporting, Reutilization, and Disposal.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., and Disposal. 252.245-7004 Section 252.245-7004 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT.... Government under surplus sales contracts; (iii) Designated by the Department of Defense as ineligible...

48 CFR 252.245-7004 - Reporting, Reutilization, and Disposal.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., and Disposal. 252.245-7004 Section 252.245-7004 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... surplus sales contracts; (iii) Designated by the Department of Defense as ineligible, debarred, or...

48 CFR 252.245-7004 - Reporting, Reutilization, and Disposal.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., and Disposal. 252.245-7004 Section 252.245-7004 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT.... Government under surplus sales contracts; (iii) Designated by the Department of Defense as ineligible...

48 CFR 252.245-7004 - Reporting, Reutilization, and Disposal.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., and Disposal. 252.245-7004 Section 252.245-7004 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... surplus sales contracts; (iii) Designated by the Department of Defense as ineligible, debarred, or...

49 CFR 234.245 - Signs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Maintenance Standards § 234.245 Signs. Each sign mounted on a highway-rail grade crossing signal post shall be maintained in good condition and be visible to the highway user. Inspections and Tests ...

6 CFR 27.245 - Review and approval of site security plans.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Review and approval of site security plans. 27.245 Section 27.245 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.245 Review and approval of site...

6 CFR 27.245 - Review and approval of site security plans.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 6 Domestic Security 1 2014-01-01 2014-01-01 false Review and approval of site security plans. 27.245 Section 27.245 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.245 Review and approval of site...

6 CFR 27.245 - Review and approval of site security plans.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 6 Domestic Security 1 2011-01-01 2011-01-01 false Review and approval of site security plans. 27.245 Section 27.245 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.245 Review and approval of site...

6 CFR 27.245 - Review and approval of site security plans.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 6 Domestic Security 1 2012-01-01 2012-01-01 false Review and approval of site security plans. 27.245 Section 27.245 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.245 Review and approval of site...

6 CFR 27.245 - Review and approval of site security plans.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 6 Domestic Security 1 2013-01-01 2013-01-01 false Review and approval of site security plans. 27.245 Section 27.245 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.245 Review and approval of site...

48 CFR 245.604-3 - Sale of surplus property.

Code of Federal Regulations, 2011 CFR

2011-10-01

.... 245.604-3 Section 245.604-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Reutilization, and... nature, condition, quantity, and location of the property; and (iv) Past sale history for like or similar...

48 CFR 245.604-3 - Sale of surplus property.

Code of Federal Regulations, 2012 CFR

2012-10-01

.... 245.604-3 Section 245.604-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Reutilization, and... nature, condition, quantity, and location of the property; and (iv) Past sale history for like or similar...

48 CFR 245.604-3 - Sale of surplus property.

Code of Federal Regulations, 2013 CFR

2013-10-01

.... 245.604-3 Section 245.604-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Reutilization, and... nature, condition, quantity, and location of the property; and (iv) Past sale history for like or similar...

48 CFR 245.604-3 - Sale of surplus property.

Code of Federal Regulations, 2014 CFR

2014-10-01

.... 245.604-3 Section 245.604-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Reutilization, and... nature, condition, quantity, and location of the property; and (iv) Past sale history for like or similar...

48 CFR 245.103-71 - Transferring Government property accountability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Transferring Government... ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY General 245.103-71 Transferring Government property accountability. Follow the procedures at PGI 245.103-71 for...

27 CFR 24.245 - Use of carbon dioxide in still wine.

Code of Federal Regulations, 2010 CFR

2010-04-01

... still wine. 24.245 Section 24.245 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS WINE Storage, Treatment and Finishing of Wine § 24.245 Use of carbon dioxide in still wine. The addition of carbon dioxide to (and retention in) still wine...

What is Neptune's D/H ratio really telling us about its water abundance?

NASA Astrophysics Data System (ADS)

Ali-Dib, Mohamad; Lakhlani, Gunjan

2018-05-01

We investigate the deep-water abundance of Neptune using a simple two-component (core + envelope) toy model. The free parameters of the model are the total mass of heavy elements in the planet (Z), the mass fraction of Z in the envelope (fenv), and the D/H ratio of the accreted building blocks (D/Hbuild).We systematically search the allowed parameter space on a grid and constrain it using Neptune's bulk carbon abundance, D/H ratio, and interior structure models. Assuming solar C/O ratio and cometary D/H for the accreted building blocks are forming the planet, we can fit all of the constraints if less than ˜15 per cent of Z is in the envelope (f_{env}^{median} ˜ 7 per cent), and the rest is locked in a solid core. This model predicts a maximum bulk oxygen abundance in Neptune of 65× solar value. If we assume a C/O of 0.17, corresponding to clathrate-hydrates building blocks, we predict a maximum oxygen abundance of 200× solar value with a median value of ˜140. Thus, both cases lead to oxygen abundance significantly lower than the preferred value of Cavalié et al. (˜540× solar), inferred from model-dependent deep CO observations. Such high-water abundances are excluded by our simple but robust model. We attribute this discrepancy to our imperfect understanding of either the interior structure of Neptune or the chemistry of the primordial protosolar nebula.

50 CFR 216.245 - Requirements for monitoring and reporting.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Requirements for monitoring and reporting. 216.245 Section 216.245 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND...

50 CFR 216.245 - Requirements for monitoring and reporting.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 10 2013-10-01 2013-10-01 false Requirements for monitoring and reporting. 216.245 Section 216.245 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND...

50 CFR 216.245 - Requirements for monitoring and reporting.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Requirements for monitoring and reporting. 216.245 Section 216.245 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND...

Evidence from Olivine-Hosted Melt Inclusions that the Martian Mantle has a Chondritic D/H Ratio and that Some Young Basalts have Assimilated Old Crust

NASA Technical Reports Server (NTRS)

Usui, Tomohiro; Alexander, O'D.; Wang, J.; Simon, J. I.; Jones, J. H.

2012-01-01

Magmatic degassing of volatile elements affects the climate and near-surface environment of Mars. Telescopic and meteorite studies have revealed that the Martian atmosphere and near-surface materials have D/H ratios 5-6 times terrestrial values [e.g., 1, 2]. Such high D/H ratios are interpreted to result from the preferential loss of H relative to heavier D from the Martian atmosphere, assuming that the original Martian water inventory had a D/H ratio similar to terrestrial values and to H in primitive meteorites [e.g., 1, 3]. However, the primordial Martian D/H ratio has, until now, not been well constrained. The uncertainty over the Martian primordial D/H ratio has arisen both from the scarcity of primitive Martian meteorites and as a result of contamination by terrestrial and, perhaps, Martian surface waters that obscure the signature of the Martian mantle. This study reports a comprehensive dataset of magmatic volatiles and D/H ratios in Martian primary magmas based on low-contamination, in situ ion microprobe analyses of olivine-hosted melt inclusions from both depleted [Yamato 980459 (Y98)] and enriched [Larkman Nunatak 06319 (LAR06)] Martian basaltic meteorites. Analyses of these primitive melts provide definitive evidence that the Martian mantle has retained a primordial D/H ratio and that young Martian basalts have assimilated old Martian crust.

48 CFR 245.608-72 - Screening excess automatic data processing equipment (ADPE).

Code of Federal Regulations, 2010 CFR

2010-10-01

... data processing equipment (ADPE). 245.608-72 Section 245.608-72 Federal Acquisition Regulations System... Reporting, Redistribution, and Disposal of Contractor Inventory 245.608-72 Screening excess automatic data... Agency, Defense Automation Resources Management Program Division (DARMP). DARMP does all required...

The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction.

PubMed

Sharma, Arpeeta; Rizky, Luddwi; Stefanovic, Nada; Tate, Mitchel; Ritchie, Rebecca H; Ward, Keith W; de Haan, Judy B

2017-03-03

Vascular dysfunction is a pivotal event in the development of diabetes-associated vascular disease. Increased inflammation and oxidative stress are major contributors to vascular dysfunction. Nrf2, a master regulator of several anti-oxidant genes and a suppressor of inflammatory NF-κB, has potential as a target to combat oxidative stress and inflammation. The aim of this study was to investigate the effects of a novel Nrf2 activator, the bardoxolone methyl derivative dh404, on endothelial function in vitro and in vivo. dh404 at 3 mg/kg was administered to male Akita mice, an established diabetic mouse model of insulin insufficiency and hyperglycemia, from 6 weeks of age. At 26 weeks of age, vascular reactivity was assessed by wire myography, pro-inflammatory expression was assessed in the aortas by qRT-PCR and immunohistochemistry, and systemic and vascular oxidative stress measurements were determined. Additionally, studies in human aortic endothelial cells (HAECs) derived from normal and diabetic patients in the presence or absence of dh404 included assessment of pro-inflammatory genes by qRT-PCR and western blotting. Oxidative stress was assessed by three methods; L-012, DCFDA and amplex red. Static adhesion assays were performed to determine the leukocyte-endothelial interaction in the presence or absence of dh404. Dh404 significantly attenuated endothelial dysfunction in diabetic Akita mice characterized by reduced contraction in response to phenylephrine and the downregulation of inflammatory genes (VCAM-1, ICAM-1, p65, IL-1β) and pro-oxidant genes (Nox1 and Nox2). Furthermore, reduced systemic and vascular oxidative stress levels were observed in diabetic Akita mice. dh404 exhibited cytoprotective effects in diabetic HAECs in vitro, reflected by significant upregulation of Nrf2-responsive genes, NAD(P)H quinone oxidoreductase 1 (NQO1) and heme oxygenase-1 (HO-1), reduction of oxidative stress markers (O 2 ·- and H 2 O 2 ), inhibition of inflammatory

13-cis-retinoic acid competitively inhibits 3 alpha-hydroxysteroid oxidation by retinol dehydrogenase RoDH-4: a mechanism for its anti-androgenic effects in sebaceous glands?

PubMed

Karlsson, Teresa; Vahlquist, Anders; Kedishvili, Natalia; Törmä, Hans

2003-03-28

Retinol dehydrogenase-4 (RoDH-4) converts retinol and 13-cis-retinol to corresponding aldehydes in human liver and skin in the presence of NAD(+). RoDH-4 also converts 3 alpha-androstanediol and androsterone into dihydrotestosterone and androstanedione, which may stimulate sebum secretion. This oxidative 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD) activity of RoDH-4 is competitively inhibited by retinol and 13-cis-retinol. Here, we further examine the substrate specificity of RoDH-4 and the inhibition of its 3 alpha-HSD activity by retinoids. Recombinant RoDH-4 oxidized 3,4-didehydroretinol-a major form of vitamin A in the skin-to its corresponding aldehyde. 13-cis-retinoic acid (isotretinoin), 3,4-didehydroretinoic acid, and 3,4-didehydroretinol, but not all-trans-retinoic acid or the synthetic retinoids acitretin and adapalene, were potent competitive inhibitors of the oxidative 3 alpha-HSD activity of RoDH-4, i.e., reduced the formation of dihydrotestosterone and androstandione in vitro. Extrapolated to the in vivo situation, this effect might explain the unique sebosuppressive effect of isotretinoin when treating acne.

The Space Telescope SI C&DH system. [Scientific Instrument Control and Data Handling Subsystem

NASA Technical Reports Server (NTRS)

Gadwal, Govind R.; Barasch, Ronald S.

1990-01-01

The Hubble Space Telescope Scientific Instrument Control and Data Handling Subsystem (SI C&DH) is designed to interface with five scientific instruments of the Space Telescope to provide ground and autonomous control and collect health and status information using the Standard Telemetry and Command Components (STACC) multiplex data bus. It also formats high throughput science data into packets. The packetized data is interleaved and Reed-Solomon encoded for error correction and Pseudo Random encoded. An inner convolutional coding with the outer Reed-Solomon coding provides excellent error correction capability. The subsystem is designed with the capacity for orbital replacement in order to meet a mission life of fifteen years. The spacecraft computer and the SI C&DH computer coordinate the activities of the spacecraft and the scientific instruments to achieve the mission objectives.

DH and ESPI laser interferometry applied to the restoration shrinkage assessment

NASA Astrophysics Data System (ADS)

Campos, L. M. P.; Parra, D. F.; Vasconcelos, M. R.; Vaz, M.; Monteiro, J.

2014-01-01

In dental restoration postoperative marginal leakage is commonly associated to polymerization shrinkage effects. In consequence the longevity and quality of restorative treatment depends on the shrinkage mechanisms of the composite filling during the polymerization. In this work the development of new techniques for evaluation of those effects under light-induced polymerization of dental nano composite fillings is reported. The composite resins activated by visible light, initiate the polymerization process by absorbing light in wavelengths at about 470 nm. The techniques employed in the contraction assessment were digital holography (DH) and Electronic Speckle Pattern Interferometry (ESPI) based on laser interferometry. A satisfactory resolution was achieved in the non-contact displacement field measurements on small objects concerning the experimental dental samples. According to a specific clinical protocol, natural teeth were used (human mandibular premolars). A class I cavity was drilled and restored with nano composite material, according to Black principles. The polymerization was monitored by DH and ESPI in real time during the cure reaction of the restoration. The total displacement reported for the material in relation of the tooth wall was 3.7 μm (natural tooth). The technique showed the entire tooth surface (wall) deforming during polymerization shrinkage.

48 CFR 245.7206 - Transmitting DD Form 1342, DoD Property Record.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Instructions 245.7206 Transmitting DD Form 1342, DoD Property Record. As a minimum, the plant clearance officer... contractor acquired the equipment; (g) Location of the industrial plant equipment; (h) Total acquisition cost..., DoD Property Record. 245.7206 Section 245.7206 Federal Acquisition Regulations System DEFENSE...

48 CFR 252.245-7000 - Government-furnished mapping, charting, and geodesy property.

Code of Federal Regulations, 2011 CFR

2011-10-01

... mapping, charting, and geodesy property. 252.245-7000 Section 252.245-7000 Federal Acquisition Regulations..., charting, and geodesy property. As prescribed in 245.107(a), use the following clause: Government-Furnished Mapping, Charting, and Geodesy Property (DEC 1991) (a) Definition—Mapping, charting, and geodesy (MC&G...

48 CFR 252.245-7000 - Government-furnished mapping, charting, and geodesy property.

Code of Federal Regulations, 2013 CFR

2013-10-01

... mapping, charting, and geodesy property. 252.245-7000 Section 252.245-7000 Federal Acquisition Regulations..., charting, and geodesy property. As prescribed in 245.107(1), use the following clause: Government-Furnished Mapping, Charting, and Geodesy Property (APR 2012) (a) Definition—Mapping, charting, and geodesy (MC&G...

48 CFR 252.245-7000 - Government-furnished mapping, charting, and geodesy property.

Code of Federal Regulations, 2012 CFR

2012-10-01

... mapping, charting, and geodesy property. 252.245-7000 Section 252.245-7000 Federal Acquisition Regulations..., charting, and geodesy property. As prescribed in 245.107(1), use the following clause: Government-Furnished Mapping, Charting, and Geodesy Property (APR 2012) (a) Definition—Mapping, charting, and geodesy (MC&G...

48 CFR 252.245-7000 - Government-furnished mapping, charting, and geodesy property.

Code of Federal Regulations, 2014 CFR

2014-10-01

... mapping, charting, and geodesy property. 252.245-7000 Section 252.245-7000 Federal Acquisition Regulations..., charting, and geodesy property. As prescribed in 245.107(1), use the following clause: Government-Furnished Mapping, Charting, and Geodesy Property (APR 2012) (a) Definition—Mapping, charting, and geodesy (MC&G...

8 CFR 245a.18 - Ineligibility and applicability of grounds of inadmissibility.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Ineligibility and applicability of grounds of inadmissibility. 245a.18 Section 245a.18 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY... STATUS UNDER SECTION 245A OF THE IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE...

8 CFR 245a.18 - Ineligibility and applicability of grounds of inadmissibility.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Ineligibility and applicability of grounds of inadmissibility. 245a.18 Section 245a.18 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY... STATUS UNDER SECTION 245A OF THE IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE...

8 CFR 245a.18 - Ineligibility and applicability of grounds of inadmissibility.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Ineligibility and applicability of grounds of inadmissibility. 245a.18 Section 245a.18 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY... STATUS UNDER SECTION 245A OF THE IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE...

Derivative of bardoxolone methyl, dh404, in an inverse dose-dependent manner lessens diabetes-associated atherosclerosis and improves diabetic kidney disease.

PubMed

Tan, Sih Min; Sharma, Arpeeta; Stefanovic, Nada; Yuen, Derek Y C; Karagiannis, Tom C; Meyer, Colin; Ward, Keith W; Cooper, Mark E; de Haan, Judy B

2014-09-01

Oxidative stress and inflammation are inextricably linked and play essential roles in the initiation and progression of diabetes complications such as diabetes-associated atherosclerosis and nephropathy. Bolstering antioxidant defenses is an important mechanism to lessen oxidative stress and inflammation. In this study, we have used a novel analog of the NFE2-related factor 2 (Nrf2) agonist bardoxolone methyl, dh404, to investigate its effects on diabetic macrovascular and renal injury in streptozotocin-induced diabetic apolipoprotein E(-/-) mice. We show that dh404, at lower but not higher doses, significantly lessens diabetes-associated atherosclerosis with reductions in oxidative stress (in plasma, urine, and vascular tissue) and proinflammatory mediators tumor necrosis factor-α, intracellular adhesion molecule-1, vascular cell adhesion molecule-1, and monocyte chemotactic protein-1 (MCP-1). We demonstrate that dh404 attenuates functional (urinary albumin-to-creatinine ratio) and structural (mesangial expansion) glomerular injury and improves renal tubular injury. Liver functional and structural studies showed that dh404 is well tolerated. Complementary in vitro studies in normal rat kidney cells showed that dh404 significantly upregulates Nrf2-responsive genes, heme oxygenase-1, NAD(P)H quinone oxidoreductase 1, and glutathione-S transferase, with inhibition of transforming growth factor-β-mediated profibrotic fibronectin, collagen I, and proinflammatory interleukin-6. Higher doses of dh404 were associated with increased expression of proinflammatory mediators MCP-1 and nuclear factor-κB. These findings suggest that this class of compound is worthy of further study to lessen diabetes complications but that dosage needs consideration. © 2014 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

48 CFR 245.7101-4 - DD Form 1640, Request for Plant Clearance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false DD Form 1640, Request for Plant Clearance. 245.7101-4 Section 245.7101-4 Federal Acquisition Regulations System DEFENSE... Forms 245.7101-4 DD Form 1640, Request for Plant Clearance. Use to request plant clearance assistance or...

Interpreting the cross-sectional flow field in a river bank based on a genetic-algorithm two-dimensional heat-transport method (GA-VS2DH)

NASA Astrophysics Data System (ADS)

Su, Xiaoru; Shu, Longcang; Chen, Xunhong; Lu, Chengpeng; Wen, Zhonghui

2016-12-01

Interactions between surface waters and groundwater are of great significance for evaluating water resources and protecting ecosystem health. Heat as a tracer method is widely used in determination of the interactive exchange with high precision, low cost and great convenience. The flow in a river-bank cross-section occurs in vertical and lateral directions. In order to depict the flow path and its spatial distribution in bank areas, a genetic algorithm (GA) two-dimensional (2-D) heat-transport nested-loop method for variably saturated sediments, GA-VS2DH, was developed based on Microsoft Visual Basic 6.0. VS2DH was applied to model a 2-D bank-water flow field and GA was used to calibrate the model automatically by minimizing the difference between observed and simulated temperatures in bank areas. A hypothetical model was developed to assess the reliability of GA-VS2DH in inverse modeling in a river-bank system. Some benchmark tests were conducted to recognize the capability of GA-VS2DH. The results indicated that the simulated seepage velocity and parameters associated with GA-VS2DH were acceptable and reliable. Then GA-VS2DH was applied to two field sites in China with different sedimentary materials, to verify the reliability of the method. GA-VS2DH could be applied in interpreting the cross-sectional 2-D water flow field. The estimates of horizontal hydraulic conductivity at the Dawen River and Qinhuai River sites are 1.317 and 0.015 m/day, which correspond to sand and clay sediment in the two sites, respectively.

D/H Ratios of Marine Lipids from Santa Barbara Basin Sediments

NASA Astrophysics Data System (ADS)

Li, C.; Sessions, A.; Kinnaman, F.; Valentine, D.

2006-12-01

With the early successful application of compound-specific D/H analyses to reconstructing paleoclimate records, most subsequent research has focused on understanding organic D/H fractionations in terrestrial environments. Thus we still know very little about natural D/H variations in lipids derived from marine organisms, or indeed if any such variations exist. We have therefore conducted an extensive survey of lipid δD values in two sediment cores collected in the Santa Barbara Basin. These data allow us to examine 1) variations between the lipid products of different organisms, 2) down-core variations due to diagenesis, and 3) differences between sediments deposited under oxic or anoxic bottom-water conditions. Our results show that considerable D/H variability between different marine products does exist. δD values of n-alkanes (except n-C35) ranged from -94 to -175 ‰, and exhibit a systematic offset between odd and even carbon numbers. The δD value of n-C35 is anomalous at -220‰. Isotopic compositions of n-alkanols range from -126 to -221 , with a pattern of progressive D depletion with chain length observed for free alcohols. δD values of sterols range from -215 to -309‰, and show no systematic variation with carbon number. However, offsets do exist between the saturated, monounsaturated, and diunsaturated sterols. Sterols as a group are strongly depleted in D relative to the bacterial-derived hopanols (-166 to -232‰), suggesting possible differences in biosynthetic fractionations by bacteria and eukaryotes. Phytol and phytane δD values roughly ranged from -360 to -410‰, while phytanol was systematically enriched at -300 to -340‰. Fatty acids encompassed much greater variability, with dD values ranging from -55 to -270‰. In general, saturated fatty acids are enriched in D relative to their unsaturated analogs, and long-chain (>C24) acids are enriched in D relative to short-chain (

31 CFR 245.4 - Advice of nonreceipt or loss.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Advice of nonreceipt or loss. 245.4... § 245.4 Advice of nonreceipt or loss. (a) In the event of the nonreceipt, loss or destruction of a check... of such check, describing the check, stating the purpose for which it was issued and giving, if...

31 CFR 245.4 - Advice of nonreceipt or loss.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Advice of nonreceipt or loss. 245.4... § 245.4 Advice of nonreceipt or loss. (a) In the event of the nonreceipt, loss or destruction of a check... of such check, describing the check, stating the purpose for which it was issued and giving, if...

48 CFR 1652.245-70 - Government property (negotiated benefits contracts).

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Government property (negotiated benefits contracts). 1652.245-70 Section 1652.245-70 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CLAUSES AND FORMS...

48 CFR 952.245-2 - Government property (fixed-price contracts).

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Government property (fixed....245-2 Government property (fixed-price contracts). Modify FAR 52.245-2 by adding “and the DOE... paragraphs (e)(1) and (e)(2) of the clause. ...

48 CFR 952.245-2 - Government property (fixed-price contracts).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Government property (fixed....245-2 Government property (fixed-price contracts). Modify FAR 52.245-2 by adding “and the DOE... paragraphs (e)(1) and (e)(2) of the clause. ...

48 CFR 245.7205 - Reporting excess and surplus contractor inventory.

Code of Federal Regulations, 2010 CFR

2010-10-01

... surplus contractor inventory. 245.7205 Section 245.7205 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Special... the report are self-explanatory except: (1) Line 1—Insert totals from line 7 of the preceding report...

48 CFR 245.107 - Contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... clause at 252.245-7000, Government-Furnished Mapping, Charting, and Geodesy Property, in solicitations and contracts when mapping, charting, and geodesy property is to be furnished. (2) Use the clause at...

48 CFR 245.107 - Contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... clause at 252.245-7000, Government-Furnished Mapping, Charting, and Geodesy Property, in solicitations and contracts when mapping, charting, and geodesy property is to be furnished. (2) Use the clause at...

48 CFR 245.107 - Contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... clause at 252.245-7000, Government-Furnished Mapping, Charting, and Geodesy Property, in solicitations and contracts when mapping, charting, and geodesy property is to be furnished. (2) Use the clause at...

FTIR spectroscopic study of biofilms formed by the rhizobacterium Azospirillum brasilense Sp245 and its mutant Azospirillum brasilense Sp245.1610

NASA Astrophysics Data System (ADS)

Tugarova, Anna V.; Scheludko, Andrei V.; Dyatlova, Yulia A.; Filip'echeva, Yulia A.; Kamnev, Alexander A.

2017-07-01

Biofilms are spatially and metabolically structured communities of microorganisms, representing a mode of their existence which is ubiquitous in nature, with cells localised within an extracellular biopolymeric matrix, attached to each other, at an interface. For plant-growth-promoting rhizobacteria (PGPR), the formation of biofilms is of special importance due to their primary localisation at the surface of plant root systems. In this work, FTIR spectroscopy was used, for the first time for bacteria of the genus Azospirillum, to comparatively study 6-day-mature biofilms formed on the surface of ZnSe discs by the rhizobacterium Azospirillum brasilense Sp245 and its mutant A. brasilense Sp245.1610. The mutant strain, having an Omegon Km insertion in the gene of lipid metabolism fabG1 on the plasmid AZOBR_p1, as compared to the wild-type strain Sp245 (see http://dx.doi.org/10.1134/S1022795413110112)

20 CFR 663.245 - What is the individual employment plan?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false What is the individual employment plan? 663.245 Section 663.245 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) ADULT AND DISLOCATED WORKER ACTIVITIES UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Intensive...

48 CFR 752.245-70 - Government property-USAID reporting requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Government property-USAID reporting requirements. 752.245-70 Section 752.245-70 Federal Acquisition Regulations System AGENCY FOR... recommendation, USAID contracts, except for those for commercial items, must contain the following preface and...

8 CFR 245.2 - Application.

Code of Federal Regulations, 2010 CFR

2010-01-01

... ADMITTED FOR PERMANENT RESIDENCE § 245.2 Application. (a) General—(1) Jurisdiction. USCIS has jurisdiction... on Form I-485, Application for Permanent Residence. The application must be accompanied by the..., deportation, or removal proceeding and who is in lawful V status shall not be deemed an abandonment of the...

48 CFR 245.608-7 - Reimbursement of cost for transfer of contractor inventory.

Code of Federal Regulations, 2010 CFR

2010-10-01

... transfer of contractor inventory. 245.608-7 Section 245.608-7 Federal Acquisition Regulations System... Reporting, Redistribution, and Disposal of Contractor Inventory 245.608-7 Reimbursement of cost for transfer of contractor inventory. The Defense Logistics Agency will pay for the movement of industrial plant...

12 CFR 19.245 - Notice of removal, suspension or debarment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Notice of removal, suspension or debarment. 19.245 Section 19.245 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY RULES OF PRACTICE AND PROCEDURE Removal, Suspension, and Debarment of Accountants From Performing Audit Services...

8 CFR 245a.20 - Decisions, appeals, motions, and certifications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... aliens previously in proceedings—(1) Upon the granting of an application. If the application for LIFE... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Decisions, appeals, motions, and certifications. 245a.20 Section 245a.20 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION...

8 CFR 245a.20 - Decisions, appeals, motions, and certifications.

Code of Federal Regulations, 2012 CFR

2012-01-01

... aliens previously in proceedings—(1) Upon the granting of an application. If the application for LIFE... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Decisions, appeals, motions, and certifications. 245a.20 Section 245a.20 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION...

8 CFR 245a.20 - Decisions, appeals, motions, and certifications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... aliens previously in proceedings—(1) Upon the granting of an application. If the application for LIFE... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Decisions, appeals, motions, and certifications. 245a.20 Section 245a.20 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION...

8 CFR 245a.20 - Decisions, appeals, motions, and certifications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... aliens previously in proceedings—(1) Upon the granting of an application. If the application for LIFE... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Decisions, appeals, motions, and certifications. 245a.20 Section 245a.20 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION...

8 CFR 245a.20 - Decisions, appeals, motions, and certifications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... aliens previously in proceedings—(1) Upon the granting of an application. If the application for LIFE... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Decisions, appeals, motions, and certifications. 245a.20 Section 245a.20 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION...

17 CFR 245.102 - Exceptions to definition of blackout period.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exceptions to definition of blackout period. 245.102 Section 245.102 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... not purchase, sell or otherwise acquire or transfer an interest in any equity security of an issuer...

17 CFR 245.100 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... a management employee of the issuer. (d) The term derivative security has the meaning set forth in... security of the issuer means any equity security or derivative security relating to an issuer, whether or... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Definitions. 245.100 Section...

DNA modification and functional delivery into human cells using Escherichia coli DH10B

PubMed Central

Narayanan, Kumaran; Warburton, Peter E.

2003-01-01

The availability of almost the complete human genome as cloned BAC libraries represents a valuable resource for functional genomic analysis, which, however, has been somewhat limited by the ability to modify and transfer this DNA into mammalian cells intact. Here we report a novel comprehensive Escherichia coli-based vector system for the modification, propagation and delivery of large human genomic BAC clones into mammalian cells. The GET recombination inducible homologous recombination system was used in the BAC host strain E.coli DH10B to precisely insert an EGFPneo cassette into the vector portion of a ∼200 kb human BAC clone, providing a relatively simple method to directly convert available BAC clones into suitable vectors for mammalian cells. GET recombination was also used for the targeted deletion of the asd gene from the E.coli chromosome, resulting in defective cell wall synthesis and diaminopimelic acid auxotrophy. Transfer of the Yersinia pseudotuberculosis invasin gene into E.coli DH10B asd– rendered it competent to invade HeLa cells and deliver DNA, as judged by transient expression of green fluorescent protein and stable neomycin-resistant colonies. The efficiency of DNA transfer and survival of HeLa cells has been optimized for incubation time and multiplicity of infection of invasive E.coli with HeLa cells. This combination of E.coli-based homologous recombination and invasion technologies using BAC host strain E.coli DH10B will greatly improve the utility of the available BAC libraries from the human and other genomes for gene expression and functional genomic studies. PMID:12711696

32 CFR 245.11 - General description of the ESCAT plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false General description of the ESCAT plan. 245.11... (CONTINUED) MISCELLANEOUS PLAN FOR THE EMERGENCY SECURITY CONTROL OF AIR TRAFFIC (ESCAT) The ESCAT Plan § 245.11 General description of the ESCAT plan. The part defines the authorities, responsibilities, and...

Diffusion-driven D/H fractionation in silicates during hydration, dehydration and degassing

NASA Astrophysics Data System (ADS)

Roskosz, Mathieu; Laporte, Didier; Deloule, Etienne; Ingrin, Jannick; Remusat, Laurent; Depecker, Christophe; Leroux, Hugues

2017-04-01

Understanding how degassing occurs during accretion and differentiation is crucial to explain the water budget of planetary bodies. In this context, the hydrogen isotopic signature of water in mantle minerals and melts is particularly useful to trace reservoirs and their interactions. Nonetheless, little is known on the influence of mantle processes on the D/H signatures of silicates. In this study, we performed controlled hydration/dehydration experiments. We explore the possibility that diffusion-driven fractionation could affect the D/H signature of partially hydrated amorphous or molten silicates and nominally anhydrous minerals (NAMs). High purity synthetic fused silica samples were annealed at between 200 and 1000°C at 20 mbar water partial pressure for 1 to 30 days. Dehydration of initially hydrated silica was also performed at 1000°C for a few hours. A set of rhyolitic samples previously synthesized in order to study bubble nucleation during magma decompression was also analyzed. Finally a natural grossular monocrystal (Zillertaler Alps, Austria), partially dehydrated in air at 800°C for 10 hours was studied. Water content and speciation were measured both by Fourier-Transform Infra-Red and Raman spectroscopies. Isotopic analyses were performed with the IMS 1270 and 1280 ion microprobes. The silica samples, the rhyolitic glasses and the grossular monocrystal exhibit typical water concentration profiles. In all cases, water speciation does not change significantly along concentration profiles. Concerning D/H signatures, no isotopic variation is detectable across amorphous silica and rhyolitic glasses. The situation is however very different in the grossular monocrystal. A strong isotopic gradient appears correlated to the water concentration profile. Our data are interpreted in terms of diffusion mechanisms in both amorphous (and molten) silicates and NAMs. Hydration, dehydration and magma degassing are probably not able to promote large diffusion

7 CFR 245.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... family shall be required to supply an equivalent value in work for the school or the school's food... SCHOOLS § 245.2 Definitions. Adult means any individual 21 years of age or older. Commodity school means a school which does not participate in the National School Lunch Program under part 210 of this chapter...

Nuclear Data Sheets for A = 245

DOE Office of Scientific and Technical Information (OSTI.GOV)

Browne, E.; Tuli,J.K.

The evaluators present in this publication spectroscopic data and level schemes from radioactive decay and nuclear reaction studies for all nuclei with mass number A = 245. This evaluation revises the earlier one by Y.A. Akovali (1992Ak05).

[Biofilm Formation by the Nonflagellated flhB1 Mutant of Azospirillum brasilense Sp245].

PubMed

Shelud'ko, A V; Filip'echeva, Yu A; Shumiliva, E M; Khlebtsov, B N; Burov, A M; Petrova, L P; Katsy, E I

2015-01-01

Azospirillum brasilense Sp245 with mixed flagellation are able to form biofilms on various surfaces. A nonflagellated mutant of this strain with inactivated chromosomal copy of the flhB gene (flhB1) was shown to exhibit specific traits at the later stages of biofilm formation on a hydrophilic (glass) surface. Mature biofilms of the flhB1::Omegon-Km mutant Sp245.1063 were considerably thinner than those of the parent strain Sp245. The biofilms of the mutant were more susceptible to the forces of hydrodynamic shear. A. brasilense Sp245 cells in biofilms were not found to possess lateral flagella. Cells with polar flagella were, however, revealed by atomic force microscopy of mature native biofilms of strain Sp245. Preservation of a polar flagellum (probably nonmotile) on the cells of A. brasilense Sp245 may enhance the biofilm stability.

24 CFR 245.315 - Materials to be submitted to HUD.

Code of Federal Regulations, 2010 CFR

2010-04-01

... local HUD office: (a) Documents to be submitted under profit and loss approach: (1) A copy of the notice... Increase in Maximum Permissible Rents § 245.315 Materials to be submitted to HUD. When the notice referred to in § 245.310 is served on the tenants, the mortgagor must send to the local HUD office copies of...

24 CFR 245.315 - Materials to be submitted to HUD.

Code of Federal Regulations, 2011 CFR

2011-04-01

... local HUD office: (a) Documents to be submitted under profit and loss approach: (1) A copy of the notice... Increase in Maximum Permissible Rents § 245.315 Materials to be submitted to HUD. When the notice referred to in § 245.310 is served on the tenants, the mortgagor must send to the local HUD office copies of...

48 CFR 245.201-71 - GFP attachments to solicitations and awards.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false GFP attachments to... Evaluation Procedures 245.201-71 GFP attachments to solicitations and awards. See PGI 245.201-71 for procedures for preparing GFP attachments to solicitations and awards. ...

Up-regulation of tumor suppressor genes by exogenous dhC16-Cer contributes to its anti-cancer activity in primary effusion lymphoma

PubMed Central

Lin, Zhen; Zabaleta, Jovanny; Dai, Lu; Qin, Zhiqiang

2017-01-01

Primary effusion lymphoma (PEL) is a rare and highly aggressive B-cell malignancy with Kaposi's sarcoma-associated herpesvirus (KSHV) infection, while lack of effective therapies. Our recent data indicated that targeting the sphingolipid metabolism by either sphingosine kinase inhibitor or exogenous ceramide species induces PEL cell apoptosis and suppresses tumor progression in vivo. However, the underlying mechanisms for these exogenous ceramides “killing” PEL cells remain largely unknown. Based on the microarray analysis, we found that exogenous dhC16-Cer treatment affected the expression of many cellular genes with important functions within PEL cells such as regulation of cell cycle, cell survival/proliferation, and apoptosis/anti-apoptosis. Interestingly, we found that a subset of tumor suppressor genes (TSGs) was up-regulated from dhC16-Cer treated PEL cells. One of these elevated TSGs, Thrombospondin-1 (THBS1) was required for dhC16-Cer induced PEL cell cycle arrest. Moreover, dhC16-Cer up-regulation of THBS1 was through the suppression of multiple KSHV microRNAs expression. Our data demonstrate that exogenous ceramides display anti-cancer activities for PEL through regulation of both host and oncogenic virus factors. PMID:28146424

Up-regulation of tumor suppressor genes by exogenous dhC16-Cer contributes to its anti-cancer activity in primary effusion lymphoma.

PubMed

Cao, Yueyu; Qiao, Jing; Lin, Zhen; Zabaleta, Jovanny; Dai, Lu; Qin, Zhiqiang

2017-02-28

Primary effusion lymphoma (PEL) is a rare and highly aggressive B-cell malignancy with Kaposi's sarcoma-associated herpesvirus (KSHV) infection, while lack of effective therapies. Our recent data indicated that targeting the sphingolipid metabolism by either sphingosine kinase inhibitor or exogenous ceramide species induces PEL cell apoptosis and suppresses tumor progression in vivo. However, the underlying mechanisms for these exogenous ceramides "killing" PEL cells remain largely unknown. Based on the microarray analysis, we found that exogenous dhC16-Cer treatment affected the expression of many cellular genes with important functions within PEL cells such as regulation of cell cycle, cell survival/proliferation, and apoptosis/anti-apoptosis. Interestingly, we found that a subset of tumor suppressor genes (TSGs) was up-regulated from dhC16-Cer treated PEL cells. One of these elevated TSGs, Thrombospondin-1 (THBS1) was required for dhC16-Cer induced PEL cell cycle arrest. Moreover, dhC16-Cer up-regulation of THBS1 was through the suppression of multiple KSHV microRNAs expression. Our data demonstrate that exogenous ceramides display anti-cancer activities for PEL through regulation of both host and oncogenic virus factors.

48 CFR 245.102 - Policy.

Code of Federal Regulations, 2011 CFR

2011-10-01

... acquired from a small business concern or a commercial item acquired under FAR part 12 or part 8. (1) The... property. The Defense Contract Management Agency (DCMA) eTools software application is the DoD data... procedures for reporting loss of Government property to eTools are set forth in the clause at 252.245-7002...

48 CFR 5152.245-9001 - Government property for installation support services (cost-reimbursement contracts).

Code of Federal Regulations, 2010 CFR

2010-10-01

... installation support services (cost-reimbursement contracts). 5152.245-9001 Section 5152.245-9001 Federal... CONTRACT CLAUSES 5152.245-9001 Government property for installation support services (cost-reimbursement contracts). As prescribed in 5145.302-3(S-91), insert the following clause: Government Property for...

33 CFR 155.245 - Damage stability information for inland oil barges.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Damage stability information for inland oil barges. 155.245 Section 155.245 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION OIL OR HAZARDOUS MATERIAL POLLUTION PREVENTION REGULATIONS FOR...

33 CFR 155.245 - Damage stability information for inland oil barges.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Damage stability information for inland oil barges. 155.245 Section 155.245 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION OIL OR HAZARDOUS MATERIAL POLLUTION PREVENTION REGULATIONS FOR...

33 CFR 155.245 - Damage stability information for inland oil barges.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Damage stability information for inland oil barges. 155.245 Section 155.245 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION OIL OR HAZARDOUS MATERIAL POLLUTION PREVENTION REGULATIONS FOR...

40 CFR 86.245-94 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES Emission Regulations for 1994 and Later Model Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.245-94 [Reserved] ...

40 CFR 80.245 - How does a small refiner apply for a sulfur baseline?

Code of Federal Regulations, 2011 CFR

2011-07-01

... sulfur baseline? 80.245 Section 80.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Hardship Provisions § 80.245 How does a small refiner apply for a sulfur baseline? (a) Any refiner seeking small...

40 CFR 80.245 - How does a small refiner apply for a sulfur baseline?

Code of Federal Regulations, 2014 CFR

2014-07-01

... sulfur baseline? 80.245 Section 80.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Hardship Provisions § 80.245 How does a small refiner apply for a sulfur baseline? (a) Any refiner seeking small...

40 CFR 80.245 - How does a small refiner apply for a sulfur baseline?

Code of Federal Regulations, 2010 CFR

2010-07-01

... sulfur baseline? 80.245 Section 80.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Hardship Provisions § 80.245 How does a small refiner apply for a sulfur baseline? (a) Any refiner seeking small...

40 CFR 80.245 - How does a small refiner apply for a sulfur baseline?

Code of Federal Regulations, 2013 CFR

2013-07-01

... sulfur baseline? 80.245 Section 80.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Hardship Provisions § 80.245 How does a small refiner apply for a sulfur baseline? (a) Any refiner seeking small...

40 CFR 80.245 - How does a small refiner apply for a sulfur baseline?

Code of Federal Regulations, 2012 CFR

2012-07-01

... sulfur baseline? 80.245 Section 80.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Hardship Provisions § 80.245 How does a small refiner apply for a sulfur baseline? (a) Any refiner seeking small...

8 CFR 245.11 - Adjustment of aliens in S nonimmigrant classification.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Adjustment of aliens in S nonimmigrant classification. 245.11 Section 245.11 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in S nonimmigrant classification. (a) Eligibility. An application on Form I-854, requesting that...

8 CFR 245.23 - Adjustment of aliens in T nonimmigrant classification.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Adjustment of aliens in T nonimmigrant classification. 245.23 Section 245.23 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in T nonimmigrant classification. (a) Eligibility of principal T-1 applicants. Except as described...

8 CFR 245.23 - Adjustment of aliens in T nonimmigrant classification.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Adjustment of aliens in T nonimmigrant classification. 245.23 Section 245.23 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in T nonimmigrant classification. (a) Eligibility of principal T-1 applicants. Except as described...

8 CFR 245.11 - Adjustment of aliens in S nonimmigrant classification.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Adjustment of aliens in S nonimmigrant classification. 245.11 Section 245.11 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in S nonimmigrant classification. (a) Eligibility. An application on Form I-854, requesting that...

8 CFR 245.23 - Adjustment of aliens in T nonimmigrant classification.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Adjustment of aliens in T nonimmigrant classification. 245.23 Section 245.23 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in T nonimmigrant classification. (a) Eligibility of principal T-1 applicants. Except as described...

8 CFR 245.11 - Adjustment of aliens in S nonimmigrant classification.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Adjustment of aliens in S nonimmigrant classification. 245.11 Section 245.11 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in S nonimmigrant classification. (a) Eligibility. An application on Form I-854, requesting that...

8 CFR 245.11 - Adjustment of aliens in S nonimmigrant classification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of aliens in S nonimmigrant classification. 245.11 Section 245.11 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in S nonimmigrant classification. (a) Eligibility. An application on Form I-854, requesting that...

8 CFR 245.23 - Adjustment of aliens in T nonimmigrant classification.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Adjustment of aliens in T nonimmigrant classification. 245.23 Section 245.23 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in T nonimmigrant classification. (a) Eligibility of principal T-1 applicants. Except as described...

8 CFR 245.23 - Adjustment of aliens in T nonimmigrant classification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of aliens in T nonimmigrant classification. 245.23 Section 245.23 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in T nonimmigrant classification. (a) Eligibility of principal T-1 applicants. Except as described...

8 CFR 245.11 - Adjustment of aliens in S nonimmigrant classification.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Adjustment of aliens in S nonimmigrant classification. 245.11 Section 245.11 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in S nonimmigrant classification. (a) Eligibility. An application on Form I-854, requesting that...

48 CFR 1852.245-70 - Contractor requests for Government-owned equipment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the equipment and the reasons why contractor-owned property cannot be used, citing the applicable FAR... 1419, DOD Industrial Plant Equipment Requisition, or equivalent format, for each item requested and (ii... Government-owned equipment. 1852.245-70 Section 1852.245-70 Federal Acquisition Regulations System NATIONAL...

45 CFR 156.245 - Treatment of direct primary care medical homes.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 1 2012-10-01 2012-10-01 false Treatment of direct primary care medical homes. 156.245 Section 156.245 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE ISSUER STANDARDS UNDER THE AFFORDABLE CARE ACT, INCLUDING...

2(2,4,5-Trichlorophenoxy) propionic acid (2,4,5-TP)

Integrated Risk Information System (IRIS)

2 ( 2,4,5 - Trichlorophenoxy ) propionic acid ( 2,4,5 - TP ) ; CASRN 93 - 72 - 1 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Hea

8 CFR 245.24 - Adjustment of aliens in U nonimmigrant status.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Adjustment of aliens in U nonimmigrant status. 245.24 Section 245.24 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in U nonimmigrant status. (a) Definitions. As used in this section, the term: (1) Continuous...

8 CFR 245.24 - Adjustment of aliens in U nonimmigrant status.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Adjustment of aliens in U nonimmigrant status. 245.24 Section 245.24 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in U nonimmigrant status. (a) Definitions. As used in this section, the term: (1) Continuous...

8 CFR 245.24 - Adjustment of aliens in U nonimmigrant status.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Adjustment of aliens in U nonimmigrant status. 245.24 Section 245.24 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in U nonimmigrant status. (a) Definitions. As used in this section, the term: (1) Continuous...

8 CFR 245.24 - Adjustment of aliens in U nonimmigrant status.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of aliens in U nonimmigrant status. 245.24 Section 245.24 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in U nonimmigrant status. (a) Definitions. As used in this section, the term: (1) Continuous...

8 CFR 245.24 - Adjustment of aliens in U nonimmigrant status.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Adjustment of aliens in U nonimmigrant status. 245.24 Section 245.24 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... aliens in U nonimmigrant status. (a) Definitions. As used in this section, the term: (1) Continuous...

40 CFR 1033.245 - Deterioration factors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... CONTROLS CONTROL OF EMISSIONS FROM LOCOMOTIVES Certifying Engine Families § 1033.245 Deterioration factors... deterioration factors that predict emission increases over the useful life of a locomotive or locomotive engine... the difference between exhaust emissions at the end of the useful life and exhaust emissions at the...

40 CFR 1033.245 - Deterioration factors.

Code of Federal Regulations, 2011 CFR

2011-07-01

... CONTROLS CONTROL OF EMISSIONS FROM LOCOMOTIVES Certifying Engine Families § 1033.245 Deterioration factors... deterioration factors that predict emission increases over the useful life of a locomotive or locomotive engine... the difference between exhaust emissions at the end of the useful life and exhaust emissions at the...

48 CFR 53.245 - Government property.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Government property. 53...) CLAUSES AND FORMS FORMS Prescription of Forms 53.245 Government property. The following forms are prescribed, as specified in this section, for use in reporting, reutilization, and disposal of Government...

48 CFR 53.245 - Government property.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Government property. 53...) CLAUSES AND FORMS FORMS Prescription of Forms 53.245 Government property. The following forms are prescribed, as specified in this section, for use in reporting, reutilization, and disposal of Government...

48 CFR 53.245 - Government property.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Government property. 53...) CLAUSES AND FORMS FORMS Prescription of Forms 53.245 Government property. The following forms are prescribed, as specified in this section, for use in reporting, reutilization, and disposal of Government...

48 CFR 53.245 - Government property.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Government property. 53...) CLAUSES AND FORMS FORMS Prescription of Forms 53.245 Government property. The following forms are prescribed, as specified in this section, for use in reporting, reutilization, and disposal of Government...

48 CFR 53.245 - Government property.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Government property. 53...) CLAUSES AND FORMS FORMS Prescription of Forms 53.245 Government property. The following forms are prescribed, as specified in this section, for use in reporting, reutilization, and disposal of Government...

Cellular Shape Memory Alloy Structures: Experiments & Modeling (Part 1)

DTIC Science & Technology

2012-08-01

High -­‐ temperature  SMAs 24 Braze  Joint  between  two  wrought  pieces  of  a  Ni24.5Pd25Ti50.5  HTSMA   (HTSMA  from...process  can  be  used   to  join  other  metal  alloys  and   high -­‐ temperature   SMAs 25 Cellular  Shape  Memory...20 30 40 50 60 910 3 4 8 5 2 T (°C) Shape memory & superelasticity 1 0 e (%) (GPa) 6 7 A NiTi wire

49 CFR 24.5 - Manner of notices.

Code of Federal Regulations, 2010 CFR

2010-10-01

... ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS General § 24.5 Manner of notices. Each notice which..., understandable language. Persons who are unable to read and understand the notice must be provided with...

49 CFR 24.5 - Manner of notices.

Code of Federal Regulations, 2011 CFR

2011-10-01

... ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS General § 24.5 Manner of notices. Each notice which..., understandable language. Persons who are unable to read and understand the notice must be provided with...

49 CFR 24.5 - Manner of notices.

Code of Federal Regulations, 2013 CFR

2013-10-01

... ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS General § 24.5 Manner of notices. Each notice which..., understandable language. Persons who are unable to read and understand the notice must be provided with...

49 CFR 24.5 - Manner of notices.

Code of Federal Regulations, 2012 CFR

2012-10-01

... ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS General § 24.5 Manner of notices. Each notice which..., understandable language. Persons who are unable to read and understand the notice must be provided with...

49 CFR 24.5 - Manner of notices.

Code of Federal Regulations, 2014 CFR

2014-10-01

... ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS General § 24.5 Manner of notices. Each notice which..., understandable language. Persons who are unable to read and understand the notice must be provided with...

Environmental control on eastern broadleaf forest species' leaf wax distributions and D/H ratios

NASA Astrophysics Data System (ADS)

Tipple, Brett J.; Pagani, Mark

2013-06-01

Local climate and environment broadly affect the deuterium/hydrogen (D/H) ratios of plant materials, however the degree to which an individual plant's leaf waxes D/H ratios are affected by these parameters remains in question. Understanding these issues is particularly important in order to reconstruct past floral transitions and changes in the paleohydrologic cycle. For this study, we sampled five co-occurring tree species, Acer rubrum, Platanus occidentalis, Juniperus virginiana, Pinus taeda, and Pinus strobus and soils at forty sites along the East Coast of the US, from Florida to Maine. Hydrogen isotopic compositions of leaf wax n-alkanes, stem and surface waters were analyzed and compared against high-resolution temperature, precipitation, relative humidity, and vapor pressure deficit data to determine environmental controls on isotopic composition. Our results demonstrate that each tree species produce a unique distribution of n-alkanes with distinct chain length pattern. Average n-alkane chain lengths recovered from soils, A. rubrum, and J. virginiana leaves show significant correlations with mean annual temperature. δD values of A. rubrum leaf n-alkanes were strongly correlated to modeled mean annual precipitation δD values and other climate parameters related to latitude (i.e. temperature, relative humidity, vapor pressure deficit), while the δD values of J. virginiana n-alkanes were not. Differences in correspondence may reflect the timing of leaf wax synthesis between the two species. Further, soil n-alkane D/H compositions were strongly correlated to modeled mean annual precipitation δD values, while the apparent hydrogen isotopic fractionation was not. These findings indicate that the isotope ratio of n-alkanes from soils in Eastern North American forests and similar ecosystems likely represents a time-averaged value that smooth out the environmental influence any one plant experiences.

Selective bio-oxidation of propane to acetone using methane-oxidizing Methylomonas sp. DH-1.

PubMed

Hur, Dong Hoon; Nguyen, Thu Thi; Kim, Donghyuk; Lee, Eun Yeol

2017-07-01

Propane is the major component of liquefied petroleum gas (LPG). Nowadays, the use of LPG is decreasing, and thus utilization of propane as a chemical feedstock is in need of development. An efficient biological conversion of propane to acetone using a methanotrophic whole cell as the biocatalyst was proposed and investigated. A bio-oxidation pathway of propane to acetone in Methylomonas sp. DH-1 was analyzed by gene expression profiling via RNA sequencing. Propane was oxidized to 2-propanol by particulate methane monooxygenase and subsequently to acetone by methanol dehydrogenases. Methylomonas sp. DH-1 was deficient in acetone-converting enzymes and thus accumulated acetone in the absence of any enzyme inhibition. The maximum accumulation, average productivity and specific productivity of acetone were 16.62 mM, 0.678 mM/h and 0.141 mmol/g cell/h, respectively, under the optimized conditions. Our study demonstrates a novel method for the bioconversion of propane to acetone using methanotrophs under mild reaction condition.

First measurements of water and D/H on Mars with ExoMars / NOMAD

NASA Astrophysics Data System (ADS)

Villanueva, Geronimo Luis; Liuzzi, Giuliano; Mumma, Michael J.; Carine Vandaele, Ann; Thomas, Ian; Smith, Michael D.; Daerden, Frank; Ristic, Bojan; Patel, Manish; Bellucci, Giancarlo; Lopez-Moreno, Jose; NOMAD Team

2017-10-01

We present preliminary data collected by the high-resolution NOMAD (Nadir and Occultation for MArs Discovery) instrument onboard the ExoMars / Trace Gas Orbiter (TGO) targeting several lines of water (H2O), deuterated water (HDO) and carbon dioxide (CO2). TGO is the first spacecraft on Mars specifically tailored to search for trace constituents, with the NOMAD instrument providing high spectral resolution (λ/dλ~ 20,000) over the 2-5 um spectral region. Such capabilities allow us to probe with unprecedented accuracy and sensitivity a multitude of organic species (e.g., CH4, CH3OH, H2CO, C2H6) and to map isotopic signatures (e.g., D/H, 13C/12C) across the whole planet.In particular, isotopic ratios are among the most valuable indicators for the loss of volatiles from an atmosphere. Because the escape rates for each isotope are slightly different (larger for the lighter forms), over long times the atmosphere becomes enriched in the heavy isotopic forms. By probing the current isotopic ratios, one can then infer the amount of matter lost to space over the planet’s evolution. Deuterium fractionation also reveals information about the cycle of water on the planet and informs us of its stability on short- and long-term scales, including its release from active regions on Mars having a characteristic D/H signature.Upon its successful launch in March/2016, we acquired critical calibration data in Apr/2016 and in June/2016, while during the Mars-Orbit-Capture phase, we also acquired Mars nadir data in Nov/2016 and in Feb-Mar/2017. Full science operations are expected to start upon final orbit insertion in early 2018. In this paper, we report initial retrievals of water and D/H derived during the Mars-Orbit-Capture phase and discuss the prospects for mapping of isotopic signatures during the nominal science phase.

48 CFR 245.7309-5 - Title.

Code of Federal Regulations, 2010 CFR

2008-10-01

... 48 Federal Acquisition Regulations System 3 2008-10-01 2008-10-01 false Title. 245.7309-5 Section... Title. (a) Unless otherwise specified in the Invitation, title to property sold under this Invitation... Contractor, title shall not vest until payment and loading are completed. (b) A Standard Form 97, Certificate...

8 CFR 245a.33 - Filing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS TO THAT OF PERSONS ADMITTED FOR LAWFUL TEMPORARY OR PERMANENT RESIDENT STATUS UNDER SECTION 245A OF THE IMMIGRATION AND... notice to appear until 90 days from the date of the initial denial, to allow the alien the opportunity to...

A Comparison between Shear Bond Strength of VMK Master Porcelain with Three Base-metal Alloys (Ni-cr-T3, VeraBond, Super Cast) and One Noble Alloy (X-33) in Metal-ceramic Restorations

PubMed Central

Ahmadzadeh, A; Neshati, A; Mousavi, N; Epakchi, S; Dabaghi Tabriz, F; Sarbazi, AH

2013-01-01

Statement of Problem: The increase in the use of metal-ceramic restorations and a high prevalence of porcelain chipping entails introducing an alloy which is more compatible with porcelain and causes a stronger bond between the two. This study is to compare shear bond strength of three base-metal alloys and one noble alloy with the commonly used VMK Master Porcelain. Materials and Method: Three different groups of base-metal alloys (Ni-cr-T3, Super Cast, and VeraBond) and one group of noble alloy (X-33) were selected. Each group consisted of 15 alloy samples. All groups went through the casting process and change from wax pattern into metal disks. The VMK Master Porcelain was then fired on each group. All the specimens were put in the UTM; a shear force was loaded until a fracture occurred and the fracture force was consequently recorded. The data were analyzed by SPSS Version 16 and One-Way ANOVA was run to compare the shear strength between the groups. Furthermore, the groups were compared two-by-two by adopting Tukey test. Results: The findings of this study revealed shear bond strength of Ni-Cr-T3 alloy was higher than the three other alloys (94 MPa or 330 N). Super Cast alloy had the second greatest shear bond strength (80. 87Mpa or 283.87 N). Both VeraBond (69.66 MPa or 245 N) and x-33 alloys (66.53 MPa or 234 N) took the third place. Conclusion: Ni-Cr-T3 with VMK Master Porcelain has the greatest shear bond strength. Therefore, employment of this low-cost alloy is recommended in metal-ceramic restorations. PMID:24724144

Polyketide synthases of Diaporthe helianthi and involvement of DhPKS1 in virulence on sunflower.

PubMed

Ruocco, Michelina; Baroncelli, Riccardo; Cacciola, Santa Olga; Pane, Catello; Monti, Maurilia Maria; Firrao, Giuseppe; Vergara, Mariarosaria; Magnano di San Lio, Gaetano; Vannacci, Giovanni; Scala, Felice

2018-01-06

The early phases of Diaporthe helianthi pathogenesis on sunflower are characterized by the production of phytotoxins that may play a role in host colonisation. In previous studies, phytotoxins of a polyketidic nature were isolated and purified from culture filtrates of virulent strains of D. helianthi isolated from sunflower. A highly aggressive isolate (7/96) from France contained a gene fragment of a putative nonaketide synthase (lovB) which was conserved in a virulent D. helianthi population. In order to investigate the role of polyketide synthases in D. helianthi 7/96, a draft genome of this isolate was examined. We were able to find and phylogenetically analyse 40 genes putatively coding for polyketide synthases (PKSs). Analysis of their domains revealed that most PKS genes of D. helianthi are reducing PKSs, whereas only eight lacked reducing domains. Most of the identified PKSs have orthologs shown to be virulence factors or genetic determinants for toxin production in other pathogenic fungi. One of the genes (DhPKS1) corresponded to the previously cloned D. helianthi lovB gene fragment and clustered with a nonribosomal peptide synthetase (NRPS) -PKS hybrid/lovastatin nonaketide like A. nidulans LovB. We used DhPKS1 as a case study and carried out its disruption through Agrobacterium-mediated transformation in the isolate 7/96. D. helianthi DhPKS1 deleted mutants were less virulent to sunflower compared to the wild type, indicating a role for this gene in the pathogenesis of the fungus. The PKS sequences analysed and reported here constitute a new genomic resource that will be useful for further research on the biology, ecology and evolution of D. helianthi and generally of fungal plant pathogens.

8 CFR 245a.21 - Confidentiality.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) Information contained in granted files may be used by the Service at a later date to make a decision: (1) On... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.21... individual employed under contract by the Service to work in connection with the LIFE Legalization provisions...

8 CFR 245a.21 - Confidentiality.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) Information contained in granted files may be used by the Service at a later date to make a decision: (1) On... IMMIGRATION AND NATIONALITY ACT Legal Immigration Family Equity (LIFE) Act Legalization Provisions § 245a.21... individual employed under contract by the Service to work in connection with the LIFE Legalization provisions...

Characterization of PEG-Like Macromolecular Coatings on Plasma Modified NiTi Alloy

NASA Astrophysics Data System (ADS)

Yang, Jun; Gao, Jiacheng; Chang, Peng; Wang, Jianhua

2008-04-01

A poly (ethylene glycol) (PEG-like) coating was developed to improve the biocompatibility of Nickel-Titanium (NiTi) alloy implants. The PEG-like macromolecular coatings were deposited on NiTi substrates at a room temperature of 298 K through a ECR (electron-cyclotron resonance) cold-plasma enhanced chemical vapor deposition method using tetraglyme (CH3-O-(CH2-CH2-O)4-CH3) as a precursor. A power supply with a frequency of 2.45 GHz was applied to ignite the plasma with Ar(argon) used as the carrier gas. Based on the atomic force microscopy (AFM) studies, a thin smooth coating on NiTi substrates with highly amorphous functional groups on the modified NiTi surfaces were mainly the same accumulated stoichiometric ratio of C and O with PEG. The vitro studies showed that platelet-rich plasma (PRP) adsorption on the modified NiTi alloy surface was significantly reduced. This study indicated that plasma surface modification changes the surface components of NiTi alloy and subsequently improves its biocompatibility.

48 CFR 245.606-70 - Instructions for completing DD Form 1342, DoD Property Record.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 245.606-70 Instructions for completing DD Form 1342, DoD Property Record. (a) The contractor shall list excess industrial plant equipment... completing DD Form 1342, DoD Property Record. 245.606-70 Section 245.606-70 Federal Acquisition Regulations...

48 CFR 252.245-7000 - Government-furnished mapping, charting, and geodesy property.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Government-furnished... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.245-7000 Government-furnished mapping, charting, and geodesy property. As prescribed in 245.107-70, use the following clause: Government-Furnished...

Day Hospital Mentalization-Based Treatment (MBT-DH) versus treatment as usual in the treatment of severe borderline personality disorder: protocol of a randomized controlled trial.

PubMed

Laurenssen, Elisabeth M P; Westra, Dieuwertje; Kikkert, Martijn J; Noom, Marc J; Eeren, Hester V; van Broekhuyzen, Anna J; Peen, Jaap; Luyten, Patrick; Busschbach, Jan J V; Dekker, Jack J M

2014-05-22

Severe borderline personality disorder is associated with a very high psychosocial and economic burden. Current treatment guidelines suggest that several manualized treatments, including day hospital Mentalization-Based Treatment (MBT-DH), are effective in these patients. However, only two randomized controlled trials have compared manualized MBT-DH with treatment as usual. Given the relative paucity of data supporting the efficacy and cost-effectiveness of MBT-DH, the possible influence of researcher allegiance in one of the trials, and potential problems with the generalization of findings to mental health systems in other countries, this multi-site randomized trial aims to investigate the efficacy and cost-effectiveness of manualized MBT-DH compared to manualized specialist treatment as usual in The Netherlands. The trial is being conducted at two sites in The Netherlands. Patients with a DSM-IV-TR diagnosis of borderline personality disorder and a score of ≥ 20 on the Borderline Personality Disorder Severity Index were randomly allocated to MBT-DH or treatment as usual. The MBT-DH program consists of a maximum of 18 months' intensive treatment, followed by a maximum of 18 months of maintenance therapy. Specialist treatment as usual is provided by the City Crisis Service in Amsterdam, a service that specializes in treating patients with personality disorders, offering manualized, non-MBT interventions including family interventions, Linehan training, social skills training, and pharmacotherapy, without a maximum time limit. Patients are assessed at baseline and subsequently every 6 months up to 36 months after the start of treatment. The primary outcome measure is the frequency and severity of manifestations of borderline personality disorder as assessed by the Borderline Personality Disorder Severity Index. Secondary outcome measures include parasuicidal behaviour, symptomatic distress, social and interpersonal functioning, personality functioning

Day Hospital Mentalization-Based Treatment (MBT-DH) versus treatment as usual in the treatment of severe borderline personality disorder: protocol of a randomized controlled trial

PubMed Central

2014-01-01

Background Severe borderline personality disorder is associated with a very high psychosocial and economic burden. Current treatment guidelines suggest that several manualized treatments, including day hospital Mentalization-Based Treatment (MBT-DH), are effective in these patients. However, only two randomized controlled trials have compared manualized MBT-DH with treatment as usual. Given the relative paucity of data supporting the efficacy and cost-effectiveness of MBT-DH, the possible influence of researcher allegiance in one of the trials, and potential problems with the generalization of findings to mental health systems in other countries, this multi-site randomized trial aims to investigate the efficacy and cost-effectiveness of manualized MBT-DH compared to manualized specialist treatment as usual in The Netherlands. Methods/design The trial is being conducted at two sites in The Netherlands. Patients with a DSM-IV-TR diagnosis of borderline personality disorder and a score of ≥ 20 on the Borderline Personality Disorder Severity Index were randomly allocated to MBT-DH or treatment as usual. The MBT-DH program consists of a maximum of 18 months’ intensive treatment, followed by a maximum of 18 months of maintenance therapy. Specialist treatment as usual is provided by the City Crisis Service in Amsterdam, a service that specializes in treating patients with personality disorders, offering manualized, non-MBT interventions including family interventions, Linehan training, social skills training, and pharmacotherapy, without a maximum time limit. Patients are assessed at baseline and subsequently every 6 months up to 36 months after the start of treatment. The primary outcome measure is the frequency and severity of manifestations of borderline personality disorder as assessed by the Borderline Personality Disorder Severity Index. Secondary outcome measures include parasuicidal behaviour, symptomatic distress, social and interpersonal functioning

The D/H ratio and the evolution of water in the terrestrial planets.

PubMed

de Bergh, C

1993-02-01

The presence of liquid water at the surface of the Earth has played a major role in the biological evolution of the Earth. None of the other terrestrial planets--Mercury, Venus and Mars--has liquid water at its surface. However, it has been suggested, since the early seventies, from both geological and atmospheric arguments that, although Venus and Mars are presently devoid of liquid water, their surfaces could have been partially or completely covered by water at some time of their evolution. There are many possible diagnostics of the long-term evolution of the planets, either from the present characteristics of their surfaces or from their present atmospheric compositions. Among them, the present value of the D/H ratio is of particular interest, although its significance in terms of long term evolution has been challenged by some authors. Recent progress has been made in this field. We now have evidence for higher D/H ratios on Mars and Venus than on Earth, with an enrichment factor of the order of 5 on Mars, and about 100 on Venus. Any scenario for the evolution of these planets must take this into The most recent models on the evolution of Mars and Venus are reviewed in light of these new measurements.

12 CFR 303.245 - Waiver of liability for commonly controlled depository institutions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Waiver of liability for commonly controlled depository institutions. 303.245 Section 303.245 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION... controlled depository institutions. (a) Scope. Section 5(e) of the FDI Act (12 U.S.C. 1815(e)) creates...

48 CFR 245.7304 - Informal bid procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Inventory 245.7304 Informal bid procedures. (a) Upon approval of the plant clearance officer, the contractor...— (1) Maximum practical competition is maintained; (2) Sources solicited are recorded; and (3) Informal... plant clearance officer prior to soliciting bids from other prospective bidders. ...

Dual function of Lactobacillus kefiri DH5 in preventing high-fat-diet-induced obesity: direct reduction of cholesterol and upregulation of PPAR-α in adipose tissue.

PubMed

Kim, Dong-Hyeon; Jeong, Dana; Kang, Il-Byeong; Kim, Hyunsook; Song, Kwang-Young; Seo, Kun-Ho

2017-11-01

Kefir consumption inhibits the development of obesity and non-alcoholic fatty liver disease (NALFD) in mice fed 60% high-fat diet (HFD). To identify the key contributor of this effect, we isolated lactic acid bacteria (LAB) from kefir and examined their anti-obesity properties from in vitro screening and in vivo validation. Thirteen kefir LAB isolates were subjected to survivability test using artificial gastrointestinal environment and cholesterol-reducing assay. Lactobacillus kefiri DH5 showed 100% survivability in gastrointestinal environments and reduced 51.6% of cholesterol; thus, this strain was selected for in vivo experiment. Compared to the HFD-saline group, the HFD-DH5 group showed significantly lower body weight (34.68 versus 31.10 g; p < 0.001), epididymal adipose tissue weight (1.39 versus 1.05 g; p < 0.001), blood triglyceride (38.2 versus 31.0 mg/dL; p < 0.01) and LDL-cholesterol levels (19.4 versus 15.7 mg/dL; p < 0.01). In addition, L. kefiri DH5 administration significantly modulated gut microbiota of HFD-fed mice. The hepatic steatosis was significantly milder (Lesion score, 2.1 versus 1.2; p < 0.001) and adipocyte diameter was significantly smaller (65.1 versus 42.2 μm; p < 0.001) in the HFD-DH5 group. L. kefiri DH5 upregulated PPAR-α, FABP4, and CPT1 expression in the epididymal adipose tissues (2.29-, 1.77-, and 2.05-fold change, respectively), suggesting a reduction in adiposity by stimulating fatty acid oxidation. L. kefiri DH5 exerts anti-obesity effects by direct reduction of cholesterol in the lumen and upregulation of PPAR-α gene in adipose tissues. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

48 CFR 245.7310-4 - Dangerous property.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Dangerous property. 245... Dangerous property. The following warning shall be included when it cannot be certified that the property is completely harmless: Dangerous Property Purchasers are warned that the property purchased may contain items...

48 CFR 245.7310-8 - Antitrust clearance.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Sale of Surplus Contractor Inventory 245.7310-8... following in the invitation: Antitrust When the property offered for sale has an acquisition cost of $3 million or more, or consists of patents, processes, techniques, or inventions, irrespective of cost, the...

24 CFR 200.245 - Hearing Officer determines facts and law: Review Committee makes final administrative decision.

Code of Federal Regulations, 2010 CFR

2010-04-01

... and law: Review Committee makes final administrative decision. 200.245 Section 200.245 Housing and... Clearance Procedure § 200.245 Hearing Officer determines facts and law: Review Committee makes final administrative decision. The Hearing Officer will determine the facts and the law relevant to the issues and will...

Disappearance of the Supergiant Progenitor of SN 2011dh in M51

NASA Astrophysics Data System (ADS)

Van Dyk, Schuyler D.; Filippenko, Alexei V.; Fox, Ori; Kelly, Patrick; Smith, Nathan

2013-03-01

We report that in Hubble Space Telescope (HST) Wide Field Camera 3 (WFC3) observations at F555W and F814W with the UVIS channel, conducted on 2013 March 2 UT as part of our Cycle 20 Snapshot program GO-13029 (PI: A. Filippenko), we have discovered that the yellow supergiant star, identified by Van Dyk et al. (2011, ApJ, 741, L28) and Maund et al. (2011, MNRAS, 739, L37) at the position of the Type IIb SN 2011dh in M51, has vanished.

7 CFR 245.6a - Verification requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE CHILD NUTRITION PROGRAMS DETERMINING ELIGIBILITY FOR FREE AND REDUCED PRICE MEALS AND FREE MILK IN... agencies serving foster, homeless, migrant, or runaway children, as defined in § 245.2. Agency records may...) General. The local educational agency must verify eligibility of children in a sample of household...

Selective Adsorption of Ethane over Ethylene in PCN-245: Impacts of Interpenetrated Adsorbent.

PubMed

Lv, Daofei; Shi, Renfeng; Chen, Yongwei; Wu, Ying; Wu, Houxiao; Xi, Hongxia; Xia, Qibin; Li, Zhong

2018-03-07

The separation of ethane from ethylene using cryogenic distillation is an energy-intensive process in the industry. With lower energetic consumption, the adsorption technology provides the opportunities for developing the industry with economic sustainability. We report an iron-based metal-organic framework PCN-245 with interpenetrated structures as an ethane-selective adsorbent for ethylene/ethane separation. The material maintains stability up to 625 K, even after exposure to 80% humid atmosphere for 20 days. Adsorptive separation experiments on PCN-245 at 100 kPa and 298 K indicated that ethane and ethylene uptakes of PCN-245 were 3.27 and 2.39 mmol, respectively, and the selectivity of ethane over ethylene was up to 1.9. Metropolis Monte Carlo calculations suggested that the interpenetrated structure of PCN-245 created greater interaction affinity for ethane than ethylene through the crossing organic linkers, which is consistent with the experimental results. This work highlights the potential application of adsorbents with the interpenetrated structure for ethane separation from ethylene.

8 CFR 245a.16 - Continuous physical presence from November 6, 1986, through May 4, 1988.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Continuous physical presence from November 6, 1986, through May 4, 1988. 245a.16 Section 245a.16 Aliens and Nationality DEPARTMENT OF HOMELAND... Equity (LIFE) Act Legalization Provisions § 245a.16 Continuous physical presence from November 6, 1986...

8 CFR 245a.16 - Continuous physical presence from November 6, 1986, through May 4, 1988.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Continuous physical presence from November 6, 1986, through May 4, 1988. 245a.16 Section 245a.16 Aliens and Nationality DEPARTMENT OF HOMELAND... Equity (LIFE) Act Legalization Provisions § 245a.16 Continuous physical presence from November 6, 1986...

8 CFR 245a.16 - Continuous physical presence from November 6, 1986, through May 4, 1988.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Continuous physical presence from November 6, 1986, through May 4, 1988. 245a.16 Section 245a.16 Aliens and Nationality DEPARTMENT OF HOMELAND... Equity (LIFE) Act Legalization Provisions § 245a.16 Continuous physical presence from November 6, 1986...

8 CFR 245a.16 - Continuous physical presence from November 6, 1986, through May 4, 1988.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Continuous physical presence from November 6, 1986, through May 4, 1988. 245a.16 Section 245a.16 Aliens and Nationality DEPARTMENT OF HOMELAND... Equity (LIFE) Act Legalization Provisions § 245a.16 Continuous physical presence from November 6, 1986...

8 CFR 245a.16 - Continuous physical presence from November 6, 1986, through May 4, 1988.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Continuous physical presence from November 6, 1986, through May 4, 1988. 245a.16 Section 245a.16 Aliens and Nationality DEPARTMENT OF HOMELAND... Equity (LIFE) Act Legalization Provisions § 245a.16 Continuous physical presence from November 6, 1986...

Large moments in bcc FexCoyMnz ternary alloy thin films

NASA Astrophysics Data System (ADS)

Snow, R. J.; Bhatkar, H.; N'Diaye, A. T.; Arenholz, E.; Idzerda, Y. U.

2018-02-01

The elemental magnetic moments and the average atomic moment of 10-20 nm thick single crystal bcc (bct) FexCoyMnz films deposited on MgO(001) have been determined as a function of a broad range of compositions. Thin film epitaxy stabilized the bcc structure for 80% of the available ternary compositional space compared to only a 23% stability region for the bulk. The films that display ferromagnetism represent 60% of the available compositional possibilities compared to 25% for the bulk. A maximum average atomic moment of 3.25 ± 0.3 μB/atom was observed for a bcc Fe9Co62Mn29 film (well above the limit of the Slater-Pauling binary alloy curve of 2.45 μB/atom). The FexCoyMnz ternary alloys that exhibit high moments can only be synthesized as ultrathin films since the bcc structure is not stable in the bulk for those compositions.

Kinetic D/H fractionation during hydration and dehydration of silicate glasses, melts and nominally anhydrous minerals

NASA Astrophysics Data System (ADS)

Roskosz, M.; Deloule, E.; Ingrin, J.; Depecker, C.; Laporte, D.; Merkel, S.; Remusat, L.; Leroux, H.

2018-07-01

The distribution of hydrogen isotopes during diffusion-driven aqueous processes in silicate glasses, melts and crystals was investigated. Hydration/dehydration experiments were performed on silica glasses at 1000 °C and 1 bar total pressure. Dehydration triggered by decompression-driven bubble nucleation and growth was performed on rhyolitic melts at 800 °C and a few hundred MPa. Hydrogen extraction from a nominally anhydrous mineral (grossular) single crystal was carried out at 800 °C and ambient pressure. After these three series of experiments, pronounced water (sensu lato) concentration profiles were observed in all recovered samples. In the grossular single-crystal, a large spatial variation in H isotopes (δD variation > 550‰) was measured across the sample. This isotopic distribution correlates with the hydrogen extraction profile. The fit to the data suggests an extreme decoupling between hydrogen and deuterium diffusion coefficients (DH and DD respectively), akin to the decoupling expected in a dilute ideal gas (DH/DD ≈ 1.41). Conversely, no measurable spatially- and time-resolved isotopic variations were measured in silicate glasses and melts. This contrasted behavior of hydrogen isotopes likely stands in the different water speciation and solution mechanisms in the three different materials. Glasses and melts contain essentially hydroxyl and molecular water groups but the mobile species is molecular water in both cases. Protonated defects make up most of the water accommodated in grossular and other nominally anhydrous minerals (NAM). These defects are also the mobile species that diffuse against polarons. These results are crucial to accurately model the degassing behavior of terrestrial and lunar magmas and to derive the initial D/H of water trapped in fluid inclusions commonly analyzed in mantle NAMs, which suffered complex geological histories.

Observations of D/H ratios in H2O, HCl, and HF on Venus and new DCl and DF line strengths

NASA Astrophysics Data System (ADS)

Krasnopolsky, V. A.; Belyaev, D. A.; Gordon, I. E.; Li, G.; Rothman, L. S.

2013-05-01

Intensities of the spectral lines in the fundamental bands of D35Cl and DF were calculated using the semi-empirical dipole moment functions derived from the most accurate and precise measurements of intensities of the ro-vibrational lines of H35Cl and HF. Values obtained in this way for the deuterated species are superior to any available measured or calculated data to date. Our study of the D/H ratios in H2O, HCl, and HF on Venus is based on spatially-resolved high-resolution spectroscopy using the CSHELL spectrograph at NASA IRTF. Search for DF on Venus using its R5 (1-0) line at 3024.054 cm-1 results in a DF mixing ratio of 0.23 ± 0.11 ppb that corresponds to (D/H)HF = 420 ± 200 times that in the Standard Mean Ocean Water (SMOW). H2O abundances on Venus were retrieved using lines at 3022.366 and 3025.761 cm-1 that were observed at an exceptionally low overhead telluric water abundance of 0.3 pr. mm. The measured H2O mixing ratios at 74 km vary insignificantly between 55°S and 55°N with a mean value of 3.2 ppm. When compared with simultaneous observations of HDO near 2722 cm-1, this results in (D/H)H2O = 95 ± 15 times SMOW. Reanalysis of the observation of the D35Cl R4 (1-0) line at 2141.540 cm-1 (Krasnopolsky, V.A. [2012b]. Icarus 219, 244-249) using the improved line strength and more thorough averaging of the spectra gives (D/H)HCl = 190 ± 50 times SMOW. The similarity of the measured (D/H)H2O = 95 ± 15 at 74 km with 120 ± 40 observed by De Bergh et al. (De Bergh, C., Bezard, B., Owen, T., Crisp, D., Maillard, J.P., Lutz, B.L. [1991]. Science 251, 547-549) below the clouds favors the constant (D/H)H2O from the surface to the mesosphere, in accord with the prediction by theory. D/H ≈ 100 removes a difference of a factor of 2 between H2O abundances in the observations by Krasnopolsky (Krasnopolsky, V.A. [2010b]. Icarus 209, 314-322) and the Venus Express nadir observations (Cottini, V., Ignatiev, N.I., Piccioni, G., Drossart, P., Grassi, D., Markiewicz

Comparative method of protein expression and isolation of EBV epitope in E.coli DH5α

NASA Astrophysics Data System (ADS)

Anyndita, Nadya V. M.; Dluha, Nurul; Himmah, Karimatul; Rifa'i, Muhaimin; Widodo

2017-11-01

Epstein-Barr Virus (EBV) or human herpes virus 4 (HHV-4) is a virus that infects human B cell and leads to nasopharyngeal carcinoma (NPC). The prevention of this disease remains unsuccessful since the vaccine has not been discovered. The objective of this study is to over-produce EBV gp350/220 epitope using several methods in E.coli DH5α. EBV epitope sequences were inserted into pMAL-p5x vector, then transformed into DH5α E.coli and over-produced using 0.3, 1 and 2 mM IPTG. Plasmid transformation was validated using AflIII restriction enzyme in 0.8% agarose. Periplasmic protein was isolated using 2 comparative methods and then analyzed using SDS-PAGE. Method A produced a protein band around 50 kDa and appeared only at transformant. Method B failed to isolate the protein, indicated by no protein band appearing. In addition, any variations in IPTG concentration didn't give a different result. Thus it can be concluded that even the lowest IPTG concentration is able to induce protein expression.

Isotopic ratios D/H and 15N/14N in giant planets

NASA Astrophysics Data System (ADS)

Marboeuf, Ulysse; Thiabaud, Amaury; Alibert, Yann; Benz, Willy

2018-04-01

The determination of isotopic ratios in planets is important since it allows us to investigate the origins and initial composition of materials. The present work aims to determine the possible range of values for isotopic ratios D/H and 15N/14N in giant planets. The main objective is to provide valuable theoretical assumptions on the isotopic composition of giant planets, their internal structure, and the main reservoirs of species. We use models of ice formation and planet formation that compute the composition of ices and gas accreted in the core and the envelope of planets. Assuming a single initial value for isotopic ratios in volatile species, and disruption of planetesimals in the envelope of gaseous planets, we obtain a wide variety of D/H and 15N/14N ratios in low-mass planets (≤100 Mearth) due to the migration pathway of planets, the accretion time of gas species whose relative abundance evolves with time, and isotope exchanges among species. If giant planets with mass greater than 100 Mearth have solar isotopic ratios such as Jupiter and Saturn due to their higher envelope mass, Neptune-type planets present values ranging between one and three times the solar value. It seems therefore difficult to use isotopic ratios in the envelope of these planets to get information about their formation in the disc. For giant planets, the ratios allow us to constrain the mass fraction of volatile species in the envelope needed to reproduce the observational data by assuming initial values for isotopic ratios in volatile species.

40 CFR 180.245 - Streptomycin; tolerances for residues.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Streptomycin; tolerances for residues...) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.245 Streptomycin; tolerances for residues. (a) General. (1) Tolerances are established for...

40 CFR 180.245 - Streptomycin; tolerances for residues.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Streptomycin; tolerances for residues...) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.245 Streptomycin; tolerances for residues. (a) General. (1) Tolerances are established for...

Multifunctional Beta Ti Alloy with Improved Specific Strength

NASA Astrophysics Data System (ADS)

Park, Chan Hee; Hong, Jae-Keun; Lee, Sang Won; Yeom, Jong-Taek

2017-12-01

Gum metals feature properties such as ultrahigh strength, ultralow elastic modulus, superelasticity, and superplasticity. They are composed of elements from Groups 4 and 5 of the periodic table and exist when the valance electron concentration (\\overline{e/a}) is 4.24; the bond order (\\overline{Bo}) is 2.87; and the "d" electron-orbital energy level (\\overline{Md}) is 2.45 eV. Typical compositions include Ti-23Nb-2Zr-0.7Ta-O and Ti-12Ta-9Nb-6Zr-3 V-O, which contain large amounts of heavy Group-5 elements such as Nb and Ta. In the present study, to improve the specific strength of a multifunctional beta Ti alloy, three alloys (Ti-20Nb-5Zr-1Fe-O, Ti-12Zr-10Mo-4Nb-O, and Ti-24Zr-9Cr-3Mo-O) were designed by satisfying the above three requirements while adding Fe, Mo, and Cr, which are not only lightweight but also have strong hardening effects. Microstructural and mechanical property analyses revealed that Ti-20Nb-5Zr-1Fe-O has a 25% higher specific strength than gum metal while maintaining an ultralow elastic modulus.

40 CFR 1045.245 - How do I determine deterioration factors from exhaust durability testing?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 34 2013-07-01 2013-07-01 false How do I determine deterioration factors from exhaust durability testing? 1045.245 Section 1045.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION...

40 CFR 1045.245 - How do I determine deterioration factors from exhaust durability testing?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 33 2011-07-01 2011-07-01 false How do I determine deterioration factors from exhaust durability testing? 1045.245 Section 1045.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION...

40 CFR 1045.245 - How do I determine deterioration factors from exhaust durability testing?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false How do I determine deterioration factors from exhaust durability testing? 1045.245 Section 1045.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION...

40 CFR 1045.245 - How do I determine deterioration factors from exhaust durability testing?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 34 2012-07-01 2012-07-01 false How do I determine deterioration factors from exhaust durability testing? 1045.245 Section 1045.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION...

40 CFR 1045.245 - How do I determine deterioration factors from exhaust durability testing?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 33 2014-07-01 2014-07-01 false How do I determine deterioration factors from exhaust durability testing? 1045.245 Section 1045.245 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION...

CLONING AND CHARACTERIZATION OF A CHROMOSOMAL DNA REGION REQUIRED FOR GROWTH ON 2,4,5-T BY PSEUDOMONAS CEPACIA AC1100

EPA Science Inventory

A series of spontaneous 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) nonmetabolizing mutants of Pseudomonas cepacia AC1100 were characterized to be defective in either 2,4,5-T uptake or conversion of this compound to 2,4,5-trichlorophenol (2,4,5-TCP). Two of these mutants, RHC22 a...

30 CFR 250.245 - What hydrogen sulfide (H2S) information must accompany the DPP or DOCD?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What hydrogen sulfide (H2S) information must accompany the DPP or DOCD? 250.245 Section 250.245 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT... Development Operations Coordination Documents (docd) § 250.245 What hydrogen sulfide (H2S) information must...

48 CFR 245.607-2 - Recovering precious metals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Recovering precious metals... Disposal of Contractor Inventory 245.607-2 Recovering precious metals. (b) Precious metals are silver, gold... office with disposition instructions for certain categories of precious metals-bearing property...

D/H isotope ratios of kerogen, bitumen, oil, and water in hydrous pyrolysis of source rocks containing kerogen types I, II, IIS, and III

USGS Publications Warehouse

Schimmelmann, A.; Lewan, M.D.; Wintsch, R.P.

1999-01-01

Immature source rock chips containing different types of kerogen (I, II, IIS, III) were artificially matured in isotopically distinct waters by hydrous pyrolysis and by pyrolysis in supercritical water. Converging isotopic trends of inorganic (water) and organic (kerogen, bitumen, oil) hydrogen with increasing time and temperature document that water-derived hydrogen is added to or exchanged with organic hydrogen, or both, during chemical reactions that take place during thermal maturation. Isotopic mass-balance calculations show that, depending on temperature (310-381??C), time (12-144 h), and source rock type, between ca. 45 and 79% of carbon-bound hydrogen in kerogen is derived from water. Estimates for bitumen and oil range slightly lower, with oil-hydrogen being least affected by water-derived hydrogen. Comparative hydrous pyrolyses of immature source rocks at 330??C for 72 h show that hydrogen in kerogen, bitumen, and expelled oil/wax ranks from most to least isotopically influenced by water-derived hydrogen in the order IIS > II ~ III > I. Pyrolysis of source rock containing type II kerogen in supercritical water at 381 ??C for 12 h yields isotopic results that are similar to those from hydrous pyrolysis at 350??C for 72 h, or 330??C for 144 h. Bulk hydrogen in kerogen contains several percent of isotopically labile hydrogen that exchanges fast and reversibly with hydrogen in water vapor at 115??C. The isotopic equilibration of labile hydrogen in kerogen with isotopic standard water vapors significantly reduces the analytical uncertainty of D/H ratios when compared with simple D/H determination of bulk hydrogen in kerogen. If extrapolation of our results from hydrous pyrolysis is permitted to natural thermal maturation at lower temperatures, we suggest that organic D/H ratios of fossil fuels in contact with formation waters are typically altered during chemical reactions, but that D/H ratios of generated hydrocarbons are subsequently little or not affected

30 CFR 550.245 - What hydrogen sulfide (H2S) information must accompany the DPP or DOCD?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What hydrogen sulfide (H2S) information must accompany the DPP or DOCD? 550.245 Section 550.245 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT... Coordination Documents (docd) § 550.245 What hydrogen sulfide (H2S) information must accompany the DPP or DOCD...

30 CFR 550.245 - What hydrogen sulfide (H2S) information must accompany the DPP or DOCD?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What hydrogen sulfide (H2S) information must accompany the DPP or DOCD? 550.245 Section 550.245 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT... Coordination Documents (docd) § 550.245 What hydrogen sulfide (H2S) information must accompany the DPP or DOCD...

30 CFR 550.245 - What hydrogen sulfide (H2S) information must accompany the DPP or DOCD?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What hydrogen sulfide (H2S) information must accompany the DPP or DOCD? 550.245 Section 550.245 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT... Coordination Documents (docd) § 550.245 What hydrogen sulfide (H2S) information must accompany the DPP or DOCD...

EPA Method 245.2: Mercury (Automated Cold Vapor Technique)

EPA Pesticide Factsheets

Method 245.2 describes procedures for preparation and analysis of drinking water samples for analysis of mercury using acid digestion and cold vapor atomic absorption. Samples are prepared using an acid digestion technique.

The Draft Genome of the Non-Host-Associated Methanobrevibacter arboriphilus Strain DH1 Encodes a Large Repertoire of Adhesin-Like Proteins

PubMed Central

Poehlein, Anja; Daniel, Rolf

2017-01-01

Methanobrevibacter arboriphilus strain DH1 is an autotrophic methanogen that was isolated from the wetwood of methane-emitting trees. This species has been of considerable interest for its unusual oxygen tolerance and has been studied as a model organism for more than four decades. Strain DH1 is closely related to other host-associated Methanobrevibacter species from intestinal tracts of animals and the rumen, making this strain an interesting candidate for comparative analysis to identify factors important for colonizing intestinal environments. Here, the genome sequence of M. arboriphilus strain DH1 is reported. The draft genome is composed of 2.445.031 bp with an average GC content of 25.44% and predicted to harbour 1964 protein-encoding genes. Among the predicted genes, there are also more than 50 putative genes for the so-called adhesin-like proteins (ALPs). The presence of ALP-encoding genes in the genome of this non-host-associated methanogen strongly suggests that target surfaces for ALPs other than host tissues also need to be considered as potential interaction partners. The high abundance of ALPs may also indicate that these types of proteins are more characteristic for specific phylogenetic groups of methanogens rather than being indicative for a particular environment the methanogens thrives in. PMID:28634433

Compact 2.45 GHz ECR Ion Source for generation of singly-charged ions

NASA Astrophysics Data System (ADS)

Fatkullin, Riyaz; Bogomolov, Sergey; Kuzmenkov, Konstantin; Efremov, Andrey

2018-04-01

2.45 GHz ECR ion sources are widely used for production of protons, single charged heavy ions and secondary radioactive ion beams. This paper describes the development of a compact ECR ion source based on 2.45 GHz coaxial resonator. The first results of extracted current measurements at different resonator configuration as a function of UHF frequency, power and gas flow are presented.

7 CFR 245.8 - Nondiscrimination practices for children eligible to receive free and reduced price meals and...

Code of Federal Regulations, 2011 CFR

2011-01-01

... their meals or milk at a different time; (e) When more than one lunch or breakfast or type of milk is... receive free and reduced price meals and free milk. 245.8 Section 245.8 Agriculture Regulations of the... PROGRAMS DETERMINING ELIGIBILITY FOR FREE AND REDUCED PRICE MEALS AND FREE MILK IN SCHOOLS § 245.8...

7 CFR 245.8 - Nondiscrimination practices for children eligible to receive free and reduced price meals and...

Code of Federal Regulations, 2010 CFR

2010-01-01

... their meals or milk at a different time; (e) When more than one lunch or breakfast or type of milk is... receive free and reduced price meals and free milk. 245.8 Section 245.8 Agriculture Regulations of the... PROGRAMS DETERMINING ELIGIBILITY FOR FREE AND REDUCED PRICE MEALS AND FREE MILK IN SCHOOLS § 245.8...

48 CFR 245.7305 - Sale approval and award.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Sale approval and award... SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Sale of Surplus Contractor Inventory 245.7305 Sale approval and award. The plant clearance officer will— (1) Evaluate bids to establish...

48 CFR 52.245-9 - Use and Charges.

Code of Federal Regulations, 2013 CFR

2013-10-01

...) Definitions. Definitions applicable to this contract are provided in the clause at 52.245-1, Government Property. Additional definitions as used in this clause include: Rental period means the calendar period... a waiver or relinquishment of any rights it may have against the Contractor stemming from the...

48 CFR 245.608-5 - Special items screening.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Disposal of Contractor Inventory 245.608-5 Special items screening. (a) Special test equipment with standard components. (1) The contractor shall report any excess special test equipment (STE) using SF 1432, Inventory Schedule D (Special Tooling and Special Test Equipment). The contractor shall list and describe on...

48 CFR 1252.245-70 - Government property reports.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Government property....245-70 Government property reports. As prescribed in (TAR) 48 CFR 1245.505-70, insert the following clause: Government Property Reports (OCT 1994) (a) The Contractor shall prepare an annual report of...

48 CFR 1252.245-70 - Government property reports.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Government property....245-70 Government property reports. As prescribed in (TAR) 48 CFR 1245.505-70, insert the following clause: Government Property Reports (OCT 1994) (a) The Contractor shall prepare an annual report of...

48 CFR 1252.245-70 - Government property reports.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Government property....245-70 Government property reports. As prescribed in (TAR) 48 CFR 1245.505-70, insert the following clause: Government Property Reports (OCT 1994) (a) The Contractor shall prepare an annual report of...

P5CDH affects the pathways contributing to Pro synthesis after ProDH activation by biotic and abiotic stress conditions

PubMed Central

Rizzi, Yanina S.; Monteoliva, Mariela I.; Fabro, Georgina; Grosso, Carola L.; Laróvere, Laura E.; Alvarez, María E.

2015-01-01

Plants facing adverse conditions usually alter proline (Pro) metabolism, generating changes that help restore the cellular homeostasis. These organisms synthesize Pro from glutamate (Glu) or ornithine (Orn) by two-step reactions that share Δ1 pyrroline-5-carboxylate (P5C) as intermediate. In the catabolic process, Pro is converted back to Glu using a different pathway that involves Pro dehydrogenase (ProDH), P5C dehydrogenase (P5CDH), and P5C as intermediate. Little is known about the coordination of the catabolic and biosynthetic routes under stress. To address this issue, we analyzed how P5CDH affects the activation of Pro synthesis, in Arabidopsis tissues that increase ProDH activity by transient exposure to exogenous Pro, or infection with Pseudomonas syringae pv. tomato. Wild-type (Col-0) and p5cdh mutant plants subjected to these treatments were used to monitor the Pro, Glu, and Orn levels, as well as the expression of genes from Pro metabolism. Col-0 and p5cdh tissues consecutively activated ProDH and Pro biosynthetic genes under both conditions. However, they manifested a different coordination between these routes. When external Pro supply was interrupted, wild-type leaves degraded Pro to basal levels at which point Pro synthesis, mainly via Glu, became activated. Under the same condition, p5cdh leaves sustained ProDH induction without reducing the Pro content but rather increasing it, apparently by stimulating the Orn pathway. In response to pathogen infection, both genotypes showed similar trends. While Col-0 plants seemed to induce both Pro biosynthetic routes, p5cdh mutant plants may primarily activate the Orn route. Our study contributes to the functional characterization of P5CDH in biotic and abiotic stress conditions, by revealing its capacity to modulate the fate of P5C, and prevalence of Orn or Glu as Pro precursors in tissues that initially consumed Pro. PMID:26284090

33 CFR 110.245 - Vieques Passage and Vieques Sound, near Vieques Island, P.R.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Vieques Passage and Vieques Sound, near Vieques Island, P.R. 110.245 Section 110.245 Navigation and Navigable Waters COAST GUARD... and Vieques Sound, near Vieques Island, P.R. (a) The anchorage grounds—(1) Vieques Passage explosives...

33 CFR 110.245 - Vieques Passage and Vieques Sound, near Vieques Island, P.R.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Vieques Passage and Vieques Sound, near Vieques Island, P.R. 110.245 Section 110.245 Navigation and Navigable Waters COAST GUARD... and Vieques Sound, near Vieques Island, P.R. (a) The anchorage grounds—(1) Vieques Passage explosives...

33 CFR 110.245 - Vieques Passage and Vieques Sound, near Vieques Island, P.R.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Vieques Passage and Vieques Sound, near Vieques Island, P.R. 110.245 Section 110.245 Navigation and Navigable Waters COAST GUARD... and Vieques Sound, near Vieques Island, P.R. (a) The anchorage grounds—(1) Vieques Passage explosives...

40 CFR 52.245 - New Source Review rules.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California §52.245 New Source Review rules. (a) Approval of the New Source Review rules for the San Joaquin Valley Unified Air Pollution Control District... Review rules for the San Joaquin Valley Unified Air Pollution Control District Rules 2020 and 2201 as...

7 CFR 245.3 - Eligibility standards and criteria.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AND FREE MILK IN SCHOOLS § 245.3 Eligibility standards and criteria. (a) Each State agency, or FNSRO... FNSRO where applicable, under paragraph (a) of this section. Such criteria shall: (1) For all schools under the jurisdiction of the local educational agency, specify the uniform family-size income criteria...

7 CFR 245.3 - Eligibility standards and criteria.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND FREE MILK IN SCHOOLS § 245.3 Eligibility standards and criteria. (a) Each State agency, or FNSRO... FNSRO where applicable, under paragraph (a) of this section. Such criteria shall: (1) For all schools under the jurisdiction of the local educational agency, specify the uniform family-size income criteria...

48 CFR 3052.245-70 - Government property reports.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Government property... CONTRACT CLAUSES Text of Provisions and Clauses 3052.245-70 Government property reports. As prescribed in (HSAR) 48 CFR 3045.505-70, insert the following clause: Government Property Reports (JUN 2006) (a) The...

48 CFR 3052.245-70 - Government property reports.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Government property... CONTRACT CLAUSES Text of Provisions and Clauses 3052.245-70 Government property reports. As prescribed in (HSAR) 48 CFR 3045.505-70, insert the following clause: Government Property Reports (JUN 2006) (a) The...

Some variables affecting hardwood control with stem injections of 2,4,5-T.

Treesearch

John L. Arend

1967-01-01

The water-soluble amine salt was at least four times more effective than the oil-soluble ester. Concentration of the 2,4,5-T, spacing of the injections, and season of the year were also important; height of the spaced injections was not. The effects of these variables and of crown size and character of the branching on hardwood control with 2,4,5-T injections are...

Influence of electrolyte composition and temperature on behaviour of AB5 hydrogen storage alloy used as negative electrode in Ni-MH batteries

NASA Astrophysics Data System (ADS)

Karwowska, Malgorzata; Jaron, Tomasz; Fijalkowski, Karol J.; Leszczynski, Piotr J.; Rogulski, Zbigniew; Czerwinski, Andrzej

2014-10-01

The AB5-type metal alloy (Mm-Ni4.1Al0.2Mn0.4Co0.45) has been investigated in different electrolytes (LiOH, NaOH, KOH, RbOH, CsOH). All of the electrochemical measurements have been performed using limited volume electrode technique (LVE). Thickness of the working electrode is nearly equal to the diameter of the grain (ca. 50 μm). Hydrogen diffusion coefficient has been determined using chronoamperometry. Hydrogen diffusion coefficient calculated for 100% state of charge reaches maximum value in KOH (DH = 4.65·10-10 cm2 s-1). We have obtained the highest value of capacity for the electrode in KOH and the lowest - in CsOH. The temperature influence on alloy capacity has been also tested. The alloy has been also characterised with SEM coupled with EDS, TGA/DSC and powder XRD. The unit cell of MmNi4.1Al0.2Mn0.4Co0.45 have been refined in the Cu5.4Yb0.8 structure type (a modified LaNi5 structure); the structure is unaffected by the electrochemical treatment.

Network Analysis of Plasmidomes: The Azospirillum brasilense Sp245 Case

PubMed Central

Fondi, Marco

2014-01-01

Azospirillum brasilense is a nitrogen-fixing bacterium living in association with plant roots. The genome of the strain Sp245, isolated in Brazil from wheat roots, consists of one chromosome and six plasmids. In this work, the A. brasilense Sp245 plasmids were analyzed in order to shed some light on the evolutionary pathways they followed over time. To this purpose, a similarity network approach was applied in order to identify the evolutionary relationships among all the A. brasilense plasmids encoded proteins; in this context a computational pipeline specifically devoted to the analysis and the visualization of the network-like evolutionary relationships among different plasmids molecules was developed. This information was supplemented with a detailed (in silico) functional characterization of both the connected (i.e., sharing homology with other sequences in the dataset) and the unconnected (i.e., not sharing homology) components of the network. Furthermore, the most likely source organism for each of the genes encoded by A. brasilense plasmids was checked, allowing the identification of possible trends of gene loss/gain in this microorganism. Data obtained provided a detailed description of the evolutionary landscape of the plasmids of A. brasilense Sp245, suggesting some of the molecular mechanisms responsible for the present-day structure of these molecules. PMID:25610702

High-Frequency Wireless Communications System: 2.45-GHz Front-End Circuit and System Integration

ERIC Educational Resources Information Center

Chen, M.-H.; Huang, M.-C.; Ting, Y.-C.; Chen, H.-H.; Li, T.-L.

2010-01-01

In this article, a course on high-frequency wireless communications systems is presented. With the 145-MHz baseband subsystem available from a prerequisite course, the present course emphasizes the design and implementation of the 2.45-GHz front-end subsystem as well as system integration issues. In this curriculum, the 2.45-GHz front-end…

Report on the Photometric Observations of the Variable Stars DH Pegasi, DY Pegasi, and RZ Cephei

NASA Astrophysics Data System (ADS)

Abu-Sharkh, I.; Fang, S.; Mehta, S.; Pham, D.

2014-12-01

We report 872 observations on two RR Lyrae variable stars, DH Pegasi and RZ Cephei, and on one SX Phoenicis variable, DY Pegasi. This paper discusses the methodology of our measurements, the light curves, magnitudes, epochs, and epoch prediction of the above stars. We also derived the period of DY Pegasi. All measurements and analyses are compared with prior publications and known values from multiple databases.

Optimization of culture conditions and medium composition for the marine algicidal bacterium Alteromonas sp. DH46 by uniform design

NASA Astrophysics Data System (ADS)

Lin, Jing; Zheng, Wei; Tian, Yun; Wang, Guizhong; Zheng, Tianling

2013-09-01

Harmful algal blooms (HABs) have led to extensive ecological and environmental issues and huge economic losses. Various HAB control techniques have been developed, and biological methods have been paid more attention. Algicidal bacteria is a general designation for bacteria which inhibit algal growth in a direct or indirect manner, and kill or damage the algal cells. A metabolite which is strongly toxic to the dinoflagellate Alexandrium tamarense was produced by strain DH46 of the alga-lysing bacterium Alteromonas sp. The culture conditions were optimized using a single-factor test method. Factors including carbon source, nitrogen source, temperature, initial pH value, rotational speed and salinity were studied. The results showed that the cultivation of the bacteria at 28°C and 180 r min-1 with initial pH 7 and 30 salt contcentration favored both the cell growth and the lysing effect of strain DH46. The optimal medium composition for strain DH46 was determined by means of uniform design experimentation, and the most important components influencing the cell density were tryptone, yeast extract, soluble starch, NaNO3 and MgSO4. When the following culture medium was used (tryptone 14.0g, yeast extract 1.63g, soluble starch 5.0 g, NaNO3 1.6 g, MgSO4 2.3 g in 1L), the largest bacterial dry weight (7.36 g L-1) was obtained, which was an enhancement of 107% compared to the initial medium; and the algal lysis rate was as high as 98.4% which increased nearly 10% after optimization.

Effective refractive index and first-order-mode cutoff conditions in InGaAsP/InP DH laser structures /lambda = 1.2-1.6 microns/

NASA Technical Reports Server (NTRS)

Botez, D.

1982-01-01

A highly accurate analytical expression for the effective refractive index in In GaAsP/InP DH lasers emitting in the 1.2-1.6 micron range is presented. This closed-form expression is used to derive simple wavelength-independent expressions for the first-order mode cutoff conditions of various lateral waveguides. The effective refractive index is a function of emission wavelength and active layer thickness, and the mode cutoff conditions are compared to experimental data from mode-stabilized 1.3 and 1.55 micron DH lasers.

48 CFR 245.7309-10 - Risk of loss.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Risk of loss. 245.7309-10...-10 Risk of loss. The Contractor is responsible for reasonable care and protection of the property until the date specified for removal. All risk of loss, damage, or destruction from any cause whatsoever...

Electrochemical oxidation of 2,4,5-trichlorophenoxyacetic acid by metal-oxide-coated Ti electrodes.

PubMed

Maharana, Dusmant; Xu, Zesheng; Niu, Junfeng; Rao, Neti Nageswara

2015-10-01

Electrochemical oxidation of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) over metal-oxide-coated Ti anodes, i.e., Ti/SnO2-Sb/Ce-PbO2, Ti/SnO2-Sb and Ti/RuO2, was examined. The degradation efficiency of over 90% was attained at 20 min at different initial concentrations (0.5-20 mg L(-1)) and initial pH values (3.1-11.2). The degradation efficiencies of 2,4,5-T on Ti/SnO2-Sb/Ce-PbO2, Ti/SnO2-Sb and Ti/RuO2 anodes were higher than 99.9%, 97.2% and 91.5% at 30 min, respectively, and the respective total organic carbon removal ratios were 65.7%, 54.6% and 37.2%. The electrochemical degradation of 2,4,5-T in aqueous solution followed pseudo-first-order kinetics. The compounds, i.e., 2,5-dichlorohydroquinone and 2,5-dihydroxy-p-benzoquinone, have been identified as the main aromatic intermediates by liquid chromatography-mass spectrometry. The results showed that the energy efficiencies of 2,4,5-T (20 mg L(-1)) degradation with Ti/SnO2-Sb/Ce-PbO2 anode at the optimal current densities from 2 to 16 mA cm(-2) ranged from 8.21 to 18.73 kWh m(-3). Copyright © 2015 Elsevier Ltd. All rights reserved.

Communication: xDH double hybrid functionals can be qualitatively incorrect for non-equilibrium geometries: Dipole moment inversion and barriers to radical-radical association using XYG3 and XYGJ-OS

NASA Astrophysics Data System (ADS)

Hait, Diptarka; Head-Gordon, Martin

2018-05-01

Double hybrid (DH) density functionals are amongst the most accurate density functional approximations developed so far, largely due to the incorporation of correlation effects from unoccupied orbitals via second order perturbation theory (PT2). The xDH family of DH functionals calculate energy directly from orbitals optimized by a lower level approach like B3LYP, without self-consistent optimization. XYG3 and XYGJ-OS are two widely used xDH functionals that are known to be quite accurate at equilibrium geometries. Here, we show that the XYG3 and XYGJ-OS functionals can be ill behaved for stretched bonds well beyond the Coulson-Fischer point, predicting unphysical dipole moments and humps in potential energy curves for some simple systems like the hydrogen fluoride molecule. Numerical experiments and analysis show that these failures are not due to PT2. Instead, a large mismatch at stretched bond-lengths between the reference B3LYP orbitals and the optimized orbitals associated with the non-PT2 part of XYG3 leads to an unphysically large non-Hellman-Feynman contribution to first order properties like forces and electron densities.

The evolution of the North Atlantic Oscillation for the last 700 years inferred from D/H isotopes in the sedimentary record of Lake Azul (Azores archipelago, Portugal).

NASA Astrophysics Data System (ADS)

Rubio de Ingles, Maria Jesus; Shanahan, Timothy M.; Sáez, Alberto; José Pueyo, Juan; Raposeiro, Pedro M.; Gonçalves, Vitor M.; Hernández, Armand; Trigo, Ricardo; Sánchez López, Guiomar; Francus, Pierre; Giralt, Santiago

2015-04-01

The δD plant leaf wax variations provide insights on precipitation and evaporation evolution through time. This proxy has been used to reconstruct the temporal evolution of the North Atlantic Oscillation (NAO) climate mode since this mode rules most of the climate variability in the central North Atlantic area. A total lipid extraction preparation and the correspondent analyses in the IRMS have been done for 100 samples from the uppermost 1.5 m of the sedimentary infill of Lake Azul (Azores archipelago, Portugal). According to the chronological model, established by 210Pb profile and 4 AMS 14C dates, this record contains the environmental history of the last 730 years. The reconstructed precipitation variations obtained from D/H isotope values, suggest that this area has suffered significant changes in its distribution and intensity rainfall patterns through time. The end of the Medieval Climate Anomaly (MCA, 1100- 1300 AD) is characterized by a progressive enrichmentof D/H isotope values which meant decreasing arid conditions. These rainfalls' increase might be interpreted by a shift from positive to negative dominance of the NAO. The Little Ice Age (LIA, 1300 - 1850 AD) was characterized by two humid periods (1300- 1550 AD and 1650 - 1850 AD) separated by a relatively dry period. These precipitation oscillations are clearly visible by marked changes in the D/H isotope values. The LIA was followed by the persistence of the positive NAO mode, exhibited by the depletion of the D/H isotope signal, which indicated an overall decrease of the precipitation in the central North Atlantic area. Surprisingly, the D/H of the last 100 years, characterized by the present global warming and a persistent positive NAO mode, display large fluctuations most possibly linked to an enhancement of the storminess which is in concordance with the data fluctuations observed in the instrumental record for the last 80 years in the archipelago. This climatic evolution is in accordance with

Detection of Deuterium in Icy Surfaces and the D/H Ratio of Icy Objects

NASA Astrophysics Data System (ADS)

Clark, Roger Nelson; Brown, Robert H.; Swayze, Gregg A.; Cruikshank, Dale P.

2017-10-01

Water ice in crystalline or amorphous form is orientationally disordered, which results in very broad absorptions. Deuterium in trace amounts goes into an ordered position, so is not broadened like H2O absorptions. The D-O stretch is located at 4.13 microns with a width of 0.027 micron. Laboratory spectral measurements on natural H2O and deuterium doped ice show the absorption is slightly asymmetric and in reflectance the band shifts from 4.132 to 4.137 microns as abundance decreases. We derive a preliminary absorption coefficient of ~ 80,000 cm^-1 for the D-O stretch compared to about 560 cm^-1 in H2O ice at 4.13 microns, enabling the detection of deuterium at levels less than Vienna Standard Mean Ocean Water (VSMOW), depending on S/N. How accurate the D/H ratios can be derived will require additional lab work and radiative transfer modeling to simultaneously derive the grain size distribution, the abundance of any contaminants, and deuterium abundance. To first order, the grain size distribution can be compensated by computing the D-O stretch band depth to 2-micron H2O ice band depth ratio, which we call Dratio. Colorado fresh water (~80% of VSMOW) has a Dratio of 0.036, at a D/H = 0.0005, the Dratio = 0.15, and at a D/H = 0.0025, the Dratio = 0.42. The VSMOW Dratio is ~ 0.045.We have used VIMS data from the Cassini spacecraft to compute large spectral averages to detect the deuterium in the rings and on the icy satellite surfaces. A B-ring, 21,882 pixel average, at 640 ms/pixel, or 3.89 hours of integration time, shows a 3.5% O-D stretch band depth and a Dratio = 0.045, indicating deuterium abundance equal to VSMOW. Rhea, using 1.89 hours of integration time shows Dratio = 0.052, or slightly higher than VSMOW. Phoebe has an unusually deep O-D stretch band of 1.85% considering the high abundance of dark material suppressing the ice absorptions. We measure a Dratio = 0.11, an enhancement of ~2.4 over VSMOW, but detailed radiative transfer modeling is needed to

40 CFR 1065.245 - Sample flow meter for batch sampling.

Code of Federal Regulations, 2011 CFR

2011-07-01

... POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Measurement Instruments Flow-Related Measurements § 1065.245... difference between a diluted exhaust sample flow meter and a dilution air meter to calculate raw exhaust flow...

40 CFR 1065.245 - Sample flow meter for batch sampling.

Code of Federal Regulations, 2014 CFR

2014-07-01

... POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Measurement Instruments Flow-Related Measurements § 1065.245... difference between a diluted exhaust sample flow meter and a dilution air meter to calculate raw exhaust flow...

40 CFR 1065.245 - Sample flow meter for batch sampling.

Code of Federal Regulations, 2013 CFR

2013-07-01

... POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Measurement Instruments Flow-Related Measurements § 1065.245... difference between a diluted exhaust sample flow meter and a dilution air meter to calculate raw exhaust flow...

40 CFR 1065.245 - Sample flow meter for batch sampling.

Code of Federal Regulations, 2012 CFR

2012-07-01

... POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Measurement Instruments Flow-Related Measurements § 1065.245... difference between a diluted exhaust sample flow meter and a dilution air meter to calculate raw exhaust flow...

20 CFR 411.245 - What are a PM's responsibilities under the Ticket to Work program?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false What are a PM's responsibilities under the Ticket to Work program? 411.245 Section 411.245 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... formats. For purposes of this section, accessible format means by media that is appropriate to a...

20 CFR 411.245 - What are a PM's responsibilities under the Ticket to Work program?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false What are a PM's responsibilities under the Ticket to Work program? 411.245 Section 411.245 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... formats. For purposes of this section, accessible format means by media that is appropriate to a...

20 CFR 411.245 - What are a PM's responsibilities under the Ticket to Work program?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false What are a PM's responsibilities under the Ticket to Work program? 411.245 Section 411.245 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... formats. For purposes of this section, accessible format means by media that is appropriate to a...

20 CFR 411.245 - What are a PM's responsibilities under the Ticket to Work program?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false What are a PM's responsibilities under the Ticket to Work program? 411.245 Section 411.245 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... formats. For purposes of this section, accessible format means by media that is appropriate to a...

20 CFR 411.245 - What are a PM's responsibilities under the Ticket to Work program?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false What are a PM's responsibilities under the Ticket to Work program? 411.245 Section 411.245 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... formats. For purposes of this section, accessible format means by media that is appropriate to a...

20 CFR 663.245 - What is the individual employment plan?

Code of Federal Regulations, 2010 CFR

2010-04-01

... ADULT AND DISLOCATED WORKER ACTIVITIES UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Intensive Services § 663.245 What is the individual employment plan? The individual employment plan is an ongoing strategy...

On the Disappearance of the Supergiant Progenitor of SN 2011dh in M51.

NASA Astrophysics Data System (ADS)

Ergon, Mattias; Sollerman, Jesper; Pursimo, Tapio; Augusteijn, Thomas; Telting, John; Smirnova, Olesja; Kankare, Erkki; Mattila, Seppo; Maund, Justyn; Fraser, Morgan

2013-03-01

We report on high quality pre- and post-explosion B, V and r band imaging obtained with the 2.56 m Nordic Optical Telescope (NOT). Difference imaging reveals a reduction of 45-60 percent in flux at the position of the yellow supergiant coincident with SN 2011dh and proposed as the progenitor by Maund et al. (2011, ApJ, 739, L37). The pre-explosion imaging was obtained on May 26 2008 (B) and May 29 2011 (V and r), the latter just 2 days before explosion.

12 CFR 24.5 - Public welfare investment after-the-fact notice and prior approval procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Public welfare investment after-the-fact notice and prior approval procedures. 24.5 Section 24.5 Banks and Banking COMPTROLLER OF THE CURRENCY... capital and surplus represented by the proposed investment and by the bank's aggregate outstanding public...

8 CFR 245.21 - Adjustment of status of certain nationals of Vietnam, Cambodia, and Laos (section 586 of Public...

Code of Federal Regulations, 2012 CFR

2012-01-01

... of Vietnam, Cambodia, and Laos (section 586 of Public Law 106-429). 245.21 Section 245.21 Aliens and... ADMITTED FOR PERMANENT RESIDENCE § 245.21 Adjustment of status of certain nationals of Vietnam, Cambodia... a lawful permanent resident, a native or citizen of Vietnam, Cambodia, or Laos who: (1) Was...

8 CFR 245.21 - Adjustment of status of certain nationals of Vietnam, Cambodia, and Laos (section 586 of Public...

Code of Federal Regulations, 2014 CFR

2014-01-01

... of Vietnam, Cambodia, and Laos (section 586 of Public Law 106-429). 245.21 Section 245.21 Aliens and... ADMITTED FOR PERMANENT RESIDENCE § 245.21 Adjustment of status of certain nationals of Vietnam, Cambodia... a lawful permanent resident, a native or citizen of Vietnam, Cambodia, or Laos who: (1) Was...

8 CFR 245.21 - Adjustment of status of certain nationals of Vietnam, Cambodia, and Laos (section 586 of Public...

Code of Federal Regulations, 2013 CFR

2013-01-01

... of Vietnam, Cambodia, and Laos (section 586 of Public Law 106-429). 245.21 Section 245.21 Aliens and... ADMITTED FOR PERMANENT RESIDENCE § 245.21 Adjustment of status of certain nationals of Vietnam, Cambodia... a lawful permanent resident, a native or citizen of Vietnam, Cambodia, or Laos who: (1) Was...