Generating Soap Bubbles by Blowing on Soap Films.

PubMed

Salkin, Louis; Schmit, Alexandre; Panizza, Pascal; Courbin, Laurent

2016-02-19

Making soap bubbles by blowing air on a soap film is an enjoyable activity, yet a poorly understood phenomenon. Working either with circular bubble wands or long-lived vertical soap films having an adjustable steady state thickness, we investigate the formation of such bubbles when a gas is blown through a nozzle onto a film. We vary film size, nozzle radius, space between the film and nozzle, and gas density, and we measure the gas velocity threshold above which bubbles are formed. The response is sensitive to containment, i.e., the ratio between film and jet sizes, and dissipation in the turbulent gas jet, which is a function of the distance from the film to the nozzle. We rationalize the observed four different regimes by comparing the dynamic pressure exerted by the jet on the film and the Laplace pressure needed to create the curved surface of a bubble. This simple model allows us to account for the interplay between hydrodynamic, physicochemical, and geometrical factors.

Surface tension of flowing soap films

NASA Astrophysics Data System (ADS)

Sane, Aakash; Mandre, Shreyas; Kim, Ildoo

2018-04-01

The surface tension of flowing soap films is measured with respect to the film thickness and the concentration of soap solution. We perform this measurement by measuring the curvature of the nylon wires that bound the soap film channel and use the measured curvature to parametrize the relation between the surface tension and the tension of the wire. We find the surface tension of our soap films increases when the film is relatively thin or made of soap solution of low concentration, otherwise it approaches an asymptotic value 30 mN/m. A simple adsorption model with only two parameters describes our observations reasonably well. With our measurements, we are also able to measure Gibbs elasticity for our soap film.

Determination of insoluble soap in agricultural soil and sewage sludge samples by liquid chromatography with ultraviolet detection.

PubMed

Cantarero, Samuel; Zafra-Gómez, Alberto; Ballesteros, Oscar; Navalón, Alberto; Vílchez, José L; Crovetto, Guillermo; Verge, Coral; de Ferrer, Juan A

2010-11-01

We have developed a new analytical procedure for determining insoluble Ca and Mg fatty acid salts (soaps) in agricultural soil and sewage sludge samples. The number of analytical methodologies that focus in the determination of insoluble soap salts in different environmental compartments is very limited. In this work, we propose a methodology that involves a sample clean-up step with petroleum ether to remove soluble salts and a conversion of Ca and Mg insoluble salts into soluble potassium salts using tripotassium ethylenediaminetetraacetate salt and potassium carbonate, followed by the extraction of analytes from the samples using microwave-assisted extraction with methanol. An improved esterification procedure using 2,4-dibromoacetophenone before the liquid chromatography with ultraviolet detection analysis also has been developed. The absence of matrix effect was demonstrated with two fatty acid Ca salts that are not commercial and are never detected in natural samples (C₁₃:₀ and C₁₇:₀). Therefore, it was possible to evaluate the matrix effect because both standards have similar environmental behavior (adsorption and precipitation) to commercial soaps (C₁₀:₀) to C₁₈:₀). We also studied the effect of the different variables on the clean-up, the conversion of Ca soap, and the extraction and derivatization procedures. The quantification limits found ranged from 0.4 to 0.8 mg/kg. The proposed method was satisfactorily applied for the development of a study on soap behavior in agricultural soil and sewage sludge samples. © 2010 SETAC.

Hard Water and Soft Soap: Dependence of Soap Performance on Water Hardness

ERIC Educational Resources Information Center

Osorio, Viktoria K. L.; de Oliveira, Wanda; El Seoud, Omar A.; Cotton, Wyatt; Easdon, Jerry

2005-01-01

The demonstration of the performance of soap in different aqueous solutions, which is due to water hardness and soap formulation, is described. The demonstrations use safe, inexpensive reagents and simple glassware and equipment, introduce important everyday topics, stimulates the students to consider the wider consequences of water hardness and…

Bernoulli Suction Effect on Soap Bubble Blowing?

NASA Astrophysics Data System (ADS)

Davidson, John; Ryu, Sangjin

2015-11-01

As a model system for thin-film bubble with two gas-liquid interfaces, we experimentally investigated the pinch-off of soap bubble blowing. Using the lab-built bubble blower and high-speed videography, we have found that the scaling law exponent of soap bubble pinch-off is 2/3, which is similar to that of soap film bridge. Because air flowed through the decreasing neck of soap film tube, we studied possible Bernoulli suction effect on soap bubble pinch-off by evaluating the Reynolds number of airflow. Image processing was utilized to calculate approximate volume of growing soap film tube and the volume flow rate of the airflow, and the Reynolds number was estimated to be 800-3200. This result suggests that soap bubbling may involve the Bernoulli suction effect.

Soap bubbles in paintings: Art and science

NASA Astrophysics Data System (ADS)

Behroozi, F.

2008-12-01

Soap bubbles became popular in 17th century paintings and prints primarily as a metaphor for the impermanence and fragility of life. The Dancing Couple (1663) by the Dutch painter Jan Steen is a good example which, among many other symbols, shows a young boy blowing soap bubbles. In the 18th century the French painter Jean-Simeon Chardin used soap bubbles not only as metaphor but also to express a sense of play and wonder. In his most famous painting, Soap Bubbles (1733/1734) a translucent and quavering soap bubble takes center stage. Chardin's contemporary Charles Van Loo painted his Soap Bubbles (1764) after seeing Chardin's work. In both paintings the soap bubbles have a hint of color and show two bright reflection spots. We discuss the physics involved and explain how keenly the painters have observed the interaction of light and soap bubbles. We show that the two reflection spots on the soap bubbles are images of the light source, one real and one virtual, formed by the curved surface of the bubble. The faint colors are due to thin film interference effects.

Handwashing and antiseptic-containing soaps in hospital

PubMed Central

Jarvis, J. D.; Wynne, C. D.; Enwright, L.; Williams, J. D.

1979-01-01

Two aspects of handwashing in hospital were considered. A study was carried out to examine the contamination of bar soap and containers, and the use of antiseptic soaps in reducing the resident flora of the skin. Swabs were collected from soap dishes on six wards and from a bacteriology laboratory on four consecutive days. The unmedicated bar soap was replaced by bar soap containing 2·5% povidone-iodine, and further swabs were collected over a period of seven days. Ninety-two isolates from 48 samples were obtained when unmedicated bar soap was used, and nine isolates from 42 samples when povidone-iodine (Betadine) soap was substituted. The number of organisms recovered when povidone-iodine soap was used was much reduced, and Pseudomonas spp were recovered in low numbers on only one occasion. Six laboratory workers took part in a study to compare bar soap with other agents—povidone-iodine soap, povidone-iodine surgical scrub, povidone-iodine alcoholic solution, chlorhexidine surgical scrub, and alcoholic chlorhexidine. Samples were collected after standard washes and after surgical gloves had been worn for 90 minutes. The effect of multiple washes was assessed by samples collected after six washes with the agent under study (three per day) followed by 90 minutes wearing surgical gloves. The average percentage reduction in normal flora obtained indicated that alcoholic chlorhexidine was superior to the other agents. PMID:500840

Preference and compliance of waterless hand-hygiene products versus soap and water.

PubMed

Carr, Michele P; Sullivan, Stefanie; Gilmore, Jenny; Rashid, Robert G

2003-09-01

To compare handwashing using traditional antimicrobial soap and water with two antimicrobial waterless hand-hygiene products for personal preference and compliance. Fifty dental and dental hygiene students were randomly chosen to participate in the study. All subjects were anonymously observed prior to the introduction of the waterless products for handwashing compliance using soap and water for 1 week. All subjects were then instructed on the use of a waterless gel and foam for handwashing. Both waterless products were used for a period of 1 week and students again were anonymously observed. A questionnaire was distributed at the conclusion of the study to determine product preference. During handwashing with soap and water, the average time the soap was in contact with the hands was 7.0 seconds. The average contact time with the gel and foam was 15.3 seconds and 20.0 seconds, respectfully. Questionnaire results indicated that the foam was significantly preferred over the gel and soap and water (54%, 28% and 16%, respectively). The foam was also significantly preferred when evaluating fragrance (52%), kindness to the skin (66%), convenience (64%) and fastest drying time (54%). Results from this study indicate that the waterless foam product was significantly preferred over the waterless gel and traditional soap and water for handwashing procedures. Since handwashing guidelines, regardless of which product used, recommend a minimum of 15 seconds to minimize the number of transient microorganisms on the hands, compliance was found only with the foam and the gel.

Making Usable, Quality Opaque or Transparent Soap

ERIC Educational Resources Information Center

Mabrouk, Suzanne T.

2005-01-01

The experiment to make opaque and transparent soap, using cold and semi boiled processes respectively, and surfactant tests that measure the pH of the prepared soap, is introduced. The experiment shows an easy method to make soap by giving a choice to select oils and scents for the soap, which can be used at home.

The formation of soap bubbles created by blowing on soap films

NASA Astrophysics Data System (ADS)

Salkin, Louis; Schmit, Alexandre; Panizza, Pascal; Courbin, Laurent

2015-11-01

Using either circular bubble wands or long-lasting vertically falling soap films having an adjustable steady state thickness, we study the formation of soap bubbles created when air is blown through a nozzle onto a soap film. We vary nozzle radius, film size, space between the film and nozzle, and gas density, and we measure the gas velocity threshold above which bubbles are generated. The response is sensitive to confinement, that is, the ratio between film and jet sizes, and dissipation in the turbulent gas jet which is a function of the distance from the nozzle to the film. We observe four different regimes that we rationalize by comparing the dynamic pressure of a jet on the film and the Laplace pressure needed to create the curved surface of a bubble.

TV watching, soap opera and happiness.

PubMed

Lu, L; Argyle, M

1993-09-01

One hundred and fourteen subjects reported the amount of time they spent watching television in general, and soap opera in particular. They also completed scales measuring happiness and other personality variables, such as extraversion and cooperativeness. In the multiple regression analysis, having controlled for the demographic variables, watching TV was related to unhappiness, whereas watching soap opera was related to happiness. Discriminant analysis showed that females, higher happiness and extraversion distinguished regular soap watchers (who nevertheless watched little TV in general) from irregular soap watchers (who nevertheless watched a lot of TV in general).

Science and Art--Rotating and Vibrating Soap Films.

ERIC Educational Resources Information Center

Ramme, Goran

1993-01-01

Describes activities concerning interference phenomena derived from illuminated rotating soap films. Suggests reflecting incident light off of the soap film onto a projection screen. Discusses several possible experiments, how to make soap solutions, and vibrating soap films. (MVL)

Soap Operas and Telenovelas: An Intercultural Critique of Soap Operas as Feminine Discourse.

ERIC Educational Resources Information Center

Lozano, Elizabeth

This paper questions some of the assumptions that permeate the current literature about soap operas and television, examining particularly the model according to which soap operas are the expression of an "essential" and universal feminine nature. The paper suggests the pertinence of a crosscultural approach to the study of melodrama as…

Comparison of hand hygiene procedures for removing Bacillus cereus spores.

PubMed

Sasahara, Teppei; Hayashi, Shunji; Hosoda, Kouichi; Morisawa, Yuji; Hirai, Yoshikazu

2014-01-01

Bacillus cereus is a spore-forming bacterium. B. cereus occasionally causes nosocomial infections, in which hand contamination with the spores plays an important role. Therefore, hand hygiene is the most important practice for controlling nosocomial B. cereus infections. This study aimed to determine the appropriate hand hygiene procedure for removing B. cereus spores. Thirty volunteers' hands were experimentally contaminated with B. cereus spores, after which they performed 6 different hand hygiene procedures. We compared the efficacy of the procedures in removing the spores from hands. The alcohol-based hand-rubbing procedures scarcely removed them. The soap washing procedures reduced the number of spores by more than 2 log10. Extending the washing time increased the spore-removing efficacy of the washing procedures. There was no significant difference in efficacy between the use of plain soap and antiseptic soap. Handwashing with soap is appropriate for removing B. cereus spores from hands. Alcohol-based hand-rubbing is not effective.

Medicinal and cosmetics soap production from Jatropha oil.

PubMed

Shahinuzzaman, M; Yaakob, Zahira; Moniruzzaman, M

2016-06-01

Soap is the most useful things which we use our everyday life in various cleansing and cosmetics purposes. Jatropha oil is nonedible oil which has more benefits to soap making. It has also cosmetics and medicinal properties. But the presence of toxic Phorbol esters in Jatropha oil is the main constrains to use it. So it is necessary to search a more suitable method for detoxifying the Jatropha oil before the use as the main ingredient of soap production. This review implies a more suitable method for removing phorbol esters from Jatropha oil. Several parameters such as the % yield of pure Jatropha oil soap, TFM value of soap, total alkali content, free caustic alkalinity content, pH, the antimicrobial activity, and CMC value of general soap should be taken into consideration for soap from detoxified Jatropha oil. © 2016 Wiley Periodicals, Inc.

Measuring Surface Tension of a Flowing Soap Film

NASA Astrophysics Data System (ADS)

Sane, Aakash; Kim, Ildoo; Mandre, Shreyas

2016-11-01

It is well known that surface tension is sensitive to the presence of surfactants and many conventional methods exist to measure it. These techniques measure surface tension either by intruding into the system or by changing its geometry. Use of conventional methods in the case of a flowing soap film is not feasible because intruding the soap film changes surface tension due to Marangoni effect. We present a technique in which we measure the surface tension in situ of a flowing soap film without intruding into the film. A flowing soap film is created by letting soap solution drip between two wires. The interaction of the soap film with the wires causes the wires to deflect which can be measured. Surface tension is calculated using a relation between curvature of the wires and the surface tension. Our measurements indicate that the surface tension of the flowing soap film for our setup is around 0.05 N/m. The nature of this technique makes it favorable for measuring surface tension of flowing soap films whose properties change on intrusion.

The antimicrobial assessment of some Nigerian herbal soap.

PubMed

Igbeneghu, O A

2013-01-01

Twenty samples of herbal soaps were evaluated for their antimicrobial activity against bacteria and yeast of significance in skin infections with the aim to provide some justification for the continued use of the soaps in the management of superficial skin infections. All the soaps were found to possess antimicrobial activity in a concentration and organism dependent manner. The soaps were more active against the gram positive organisms than the Gram negative organisms while none of the soaps had activity against the tested yeasts. Only 35% of the soaps were appropriately packaged with adequate directions for use and storage. The study showed that the tested soaps possessed antimicrobial properties and they can contribute to the treatment and management of skin infections caused by bacteria if well prepared with the appropriate plant materials to target specific causative organisms and packaged with appropriate directions for use and storage.

National and regional assessment of the antibacterial soap market: a step toward determining the impact of prevalent antibacterial soaps.

PubMed

Perencevich, E N; Wong, M T; Harris, A D

2001-10-01

Consumer antibacterial soaps contain triclosan or triclocarban. No scientific data have been published to suggest that the use of antibacterial agents in household products prevents infection, and triclosan resistance mechanisms have recently been identified. Little data are available regarding the prevalence of antibacterial agents contained in consumer soaps. In a physician-performed survey of 23 stores in 10 states from December 1999 to April 2000, investigators determined the number of national brand liquid and bar soaps and percent of each containing antibacterial agents sold at national chain, regional grocery, and Internet stores. Antibacterial agents were present in 76% of liquid soaps and 29% of bar soaps available nationally. There were no differences found between national, regional, and Internet stores. Overall, 45% of surveyed soaps contain antibacterial agents. With limited documented benefits and experimental laboratory evidence suggesting possible adverse effects on the emergence of antimicrobial resistance, consumer antibacterial use of this magnitude should be questioned.

Sex on the Soap Operas: Afternoon Delight.

ERIC Educational Resources Information Center

Greenberg, Bradley S.; And Others

1981-01-01

Examines the portrayal of intimate sexual behavior on soap operas and concludes that soap operas have more sexual content than do prime-time programs, but the types of intimacies differ. Notes that soap operas are potentially a major force in the transmission of values and sexual information to youthful viewers. (PD)

Marangoni and Gibbs elasticity of flowing soap films

NASA Astrophysics Data System (ADS)

Kim, Ildoo; Sane, Aakash; Mandre, Shreyas

2017-11-01

A flowing soap film has two elasticities. Marangoni elasticity dynamically stabilizes the film from sudden disturbance, and Gibbs elasticity is an equilibrium property that influences the film's persistence over time. In our experimental investigation, we find that Marangoni elasticity is 22 mN/m independent of the film thickness. On the other hand, Gibbs elasticity depends both on the film thickness and the soap concentration. Interestingly, the soap film made of dilute soap solution has the greater Gibbs elasticity, which is not consistent to the existing theory. Such discrepancy is originated from the flowing nature of our soap films, in which surfactants are continuously replenished.

Spectroscopic and Thermal Behavior of Chromium Soaps

NASA Astrophysics Data System (ADS)

Mehrotra, K. N.; Jain, Mamta

1996-02-01

The physicochemical characteristics of chromium soaps (myristate and stearate) were investigated in the solid state (thermal, X-ray, and IR measurements) and in solutions (spectrophotometric measurements). The thermal measurements showed that the decomposition of chromium soaps is a two-step process. The soap decomposed into chromium oxycarboxylate, ketone, and carbon dioxide in the first step and the intermediate oxycarboxylate underwent further decomposition to chromium trioxide in the second step. The results showed that the second step is kinetically of zero order and the values of energy of activation for the first and second steps lie in the ranges 6-7 and 17-18 kcal mol-1, respectively. The X-ray diffraction results showed that these soaps possess double-layer structure with molecular axes slightly inclined to the basal plane. The infrared results revealed that the fatty acids exist with dimeric structure through hydrogen bonding between two molecules of fatty acids whereas the metal-to-oxygen bonds in chromium soaps are not purely ionic but possess considerable covalent character. The results of spectrophotometric measurements also confirmed the somewhat covalent nature of chromium soaps in solutions in dichloromethane.

Communication networks, soap films and vectors

NASA Astrophysics Data System (ADS)

Clark, R. C.

1981-01-01

The problem of constructing the least-cost network of connections between arbitrarily placed points is one that is common and which can be very important financially. The network may consist of motorways between towns, a grid of electric power lines, buried gas or oil pipe lines or telephone cables. Soap films trapped between parallel planes with vertical pins between them provide a 'shortest path' network and Isenberg (1975) has suggested that soap films of this sort be used to model communication networks. However soap films are unable to simulate the different costs of laying, say, a three-lane motorway instead of a two-lane one or of using a larger pipeline to take the flow from two smaller ones. Soap films, however, have considerable intrinsic interest. In the article the emphasis is on the use of soap films and communication networks as a practical means of illustrating the importance of vector and matrix methods in geometry. The power of vector methods is illustrated by the fact that given any soap film network the total length of the film can be written down by inspection if the vector positions of the pins are known. It is also possible to predict the boundaries at which 'catastrophes' occur and to decide which network has the least total length. In the field of communication networks a method is given of designing the minimum cost network linking, say, a number of oilwells, which produce at different rates to an outlet terminal.

THE GERMICIDAL AND HEMOLYTIC ACTION OF α-BROM SOAPS

PubMed Central

Eggerth, Arnold H.

1929-01-01

1. The soaps of the α-brom fatty acids are usually more germicidal than the unsubstituted soaps. Only when B. typhosus was the test organism was there no increase in germicidal action. 2. For any test organism, germicidal action of the brominated soaps increases rapidly with increasing molecular weight up to a certain point, then diminishes. This is likewise true of the hemolytic titer. The point of maximal germicidal action varies with the different species of tests organisms. In the series studied, brominated soaps of 12 and 14 carbon atoms were most germicidal for the Gram-negative organisms, while soaps of 16 and 18 carbon atoms were most germicidal for Gram-positive organisms. 3. The brominated soaps are, in general, more active in acid that in neutral or alkaline reactions. The reasons for this have been discussed in a previous paper, in which a similar phenomenon with unsubstituted soaps was observed. 4. For certain organisms, the brominated soaps are among the most rapid and potent germicides known. PMID:19869537

Soap Gets in Your Eyes

PubMed Central

Laidlaw, Alistair; Bloom, Philip

1990-01-01

We present a previously unreported series of five cases of acute angle closure glaucoma associated with watching the Australia soap opera "Neighbours". Two cases were bilateral and associated with watching two episodes of "Neighbours" on the same day. The pathogenesis, and possible role of watching soap operas in the causation of primary angle closure glaucoma is discussed. PMID:1369543

Stability conditions and mechanism of cream soaps: role of glycerol.

PubMed

Sagitani, Hiromichi

2014-01-01

Fatty acids, fatty acid potassium soaps, glycerol and water are essential ingredients in the production of stable cream soaps. In this study, the behavior of these components in solution was investigated to elucidate the stability conditions and mechanism of cream soaps. It was determined that the cream soaps were a dispersion of 1:1 acid soap (1:1 molar ratio of potassium soap/fatty acid) crystals in the lamellar gel phase, which has confirmed from the phase behavior diagrams and small angle X-ray scattering data. Glycerol was crucial ingredient in the formation of the lamellar gel phase. The cleansing process of the cream soaps was also evaluated using the same diagrams. The structure of the continuous phase in cream soaps changed from lamellar gel to a micellar aqueous solution upon the addition of water. This structural change during the washing process is important in producing the foaming activity of acid soaps to wash away dirt or excess fats from the skin surface.

Bacterial flora of commonly used soaps in three hospitals in Nigeria.

PubMed

Afolabi, B A; Oduyebo, O O; Ogunsola, F T

2007-10-01

To obtain general information on soap use and soap bacterial flora, and to assess the risk of transmission of organisms from contaminated soap to patients. Descriptive study. Three hospitals in an urban area of Lagos, Nigeria. A teaching (761 bed) hospital, a general hospital (a 51 bed secondary healthcare facility) and a private hospital (a 30 bed private community with a surgical specialty). Bar soaps were much more commonly used than liquid soaps. Out of the thirty six bar soaps and their receptacles studied, 19 (52.8%) were found wet, nine (25%) dry, five (13.9%) very dry, and three (8.3%) in a pool of water. A total of 39% soaps and 75% of receptacles were contaminated. Thirty three percent of the dry soaps and 68.4% of the wet soaps were contaminated. None of the very dry soaps and all in a pool of water were contaminated. The bacteria isolated from soaps included Pseudomonas aeruginosa (89.5%) and Klebsiella pneumoniae (10.5%), while Pseudomonas aeruginosa (70.6%), Klebsiella pneumoniae (14.7%), Staphylococcus aureus (11.8%) and Serratia marcescens (2.9%) were isolated from the receptacles. The antibiogram showed that the Pseudomonas aeruginosa isolated from the soaps and their containers (sinks) were distinct from those obtained from colonised or infected wounds. The soap contamination rates correlated with the conditions in which the soaps were kept. The type of soap containers in particular, played a vital role in keeping the soap dry or wet. In all the hospitals studied, the policies on soap use, if any, were not in agreement with the recommended guidelines. The healthcare workers need to be re-educated on these guidelines.

Soaps and Detergents--A 'Social' Treatment.

ERIC Educational Resources Information Center

Rust, S. C.

1979-01-01

Describes how social aspects of science can be incorporated into teaching soap and detergents in British secondary chemistry and general science courses. Historical background to the use and production of soap and the development of detergents are also presented. (HM)

Drag reduction in hydrocarbon-aluminum soap polymer systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zakin, J.L.; Lee, K.C.

1972-01-01

While the drag-reducing capability of solutions of aluminum soap in hydrocarbons in turbulent flow has been known for over 20 yr, investigations of the effects of concentration, soap type, and aging on drag reduction have only recently begun. The effects of aging, shear stress, and the presence of peptizers on drag reduction of hydrocarbon dispersions of aluminum soaps at relatively low concentrations were studied. These systems showed an apparent upper critical shear stress above which drag reduction was gradually lost. Degradation of the soap micelle structure occurred relatively rapidly above this point and recovery was slow. The effect of peptizersmore » is complex. In some situations, it enhanced and in others reduced the drag-reducing ability of the soap polymers. (13 refs.)« less

Consumer antibacterial soaps: effective or just risky?

PubMed

Aiello, Allison E; Larson, Elaine L; Levy, Stuart B

2007-09-01

Much has been written recently about the potential hazards versus benefits of antibacterial (biocide)-containing soaps. The purpose of this systematic literature review was to assess the studies that have examined the efficacy of products containing triclosan, compared with that of plain soap, in the community setting, as well as to evaluate findings that address potential hazards of this use--namely, the emergence of antibiotic-resistant bacteria. The PubMed database was searched for English-language articles, using relevant keyword combinations for articles published between 1980 and 2006. Twenty-seven studies were eventually identified as being relevant to the review. Soaps containing triclosan within the range of concentrations commonly used in the community setting (0.1%-0.45% wt/vol) were no more effective than plain soap at preventing infectious illness symptoms and reducing bacterial levels on the hands. Several laboratory studies demonstrated evidence of triclosan-adapted cross-resistance to antibiotics among different species of bacteria. The lack of an additional health benefit associated with the use of triclosan-containing consumer soaps over regular soap, coupled with laboratory data demonstrating a potential risk of selecting for drug resistance, warrants further evaluation by governmental regulators regarding antibacterial product claims and advertising. Further studies of this issue are encouraged.

Soaps and detergents: understanding their composition and effect.

PubMed

Kirsner, R S; Froelich, C W

1998-03-01

Soaps have been used for thousands of years as part of religious ceremonies and daily life. Derived from fatty acids or triglycerides (fats or oils) into their alkali derivatives through a process called saponification, soaps are important for healthcare professionals in preventing the spread of disease. Partly due to their alkaline nature, soaps are limited by their irritancy to the skin and their tendency to form insoluble and inactive salts when combined with either hard water or sea water. Therefore, soap alternatives or synthetic detergents have been developed. Detergents are classified into four groups: anionic, cationic, amphoteric, and non-ionic. These four groups are based on the hydrophilic qualities and surfactants they possess. Each group has characteristics that pertain to its main uses, irritancy, and toxicity. Understanding soaps and detergents may assist clinicians in making intelligent choices when using these agents on their patients as either skin cleansers or wound cleansers. Understanding the characteristics of soaps and detergents is especially important when dealing with at-risk patients such as the elderly.

Soap Operas and Sexual Activity: A Decade Later.

ERIC Educational Resources Information Center

Greenberg, Bradley S.; Busselle, Rick W.

1996-01-01

Finds that soap operas analyzed in 1994 contain more frequent sexual incidence on an hourly average, both within the same soaps analyzed a decade earlier and even more so on two additional very popular soaps. Shows that the more frequent sex centers on physical intercourse, primarily among partners not married to anyone; and sexual activity is…

Profiling the Adolescent Soap Opera Viewer.

ERIC Educational Resources Information Center

Alexander, Alison; And Others

Observing that plot and character changes in the daytime television serials has increased the teen and preteen share of soap opera audiences, a study compared demographic, personal experience, and attitudinal variables among adolescent soap opera fans, occasional viewers, and nonviewers. Data were collected from 230 students in the classrooms of…

Influence of Soap Characteristics and Food Service Facility Type on the Degree of Bacterial Contamination of Open, Refillable Bulk Soaps.

PubMed

Schaffner, Donald W; Jensen, Dane; Gerba, Charles P; Shumaker, David; Arbogast, James W

2018-02-01

Concern has been raised regarding the public health risks from refillable bulk-soap dispensers because they provide an environment for potentially pathogenic bacteria to grow. This study surveyed the microbial quality of open refillable bulk soap in four different food establishment types in three states. Two hundred ninety-six samples of bulk soap were collected from food service establishments in Arizona, New Jersey, and Ohio. Samples were tested for total heterotrophic viable bacteria, Pseudomonas, coliforms and Escherichia coli, and Salmonella. Bacteria were screened for antibiotic resistance. The pH, solids content, and water activity of all soap samples were measured. Samples were assayed for the presence of the common antibacterial agents triclosan and parachlorometaxylenol. More than 85% of the soap samples tested contained no detectable microorganisms, but when a sample contained any detectable microorganisms, it was most likely contaminated at a very high level (∼7 log CFU/mL). Microorganisms detected in contaminated soap included Klebsiella oxytoca, Serratia liquefaciens, Shigella sonnei, Enterobacter gergoviae, Serratia odorifera, and Enterobacter cloacae. Twenty-three samples contained antibiotic-resistant organisms, some of which were resistant to two or more antibiotics. Every sample containing less than 4% solids had some detectable level of bacteria, whereas no samples with greater than 14% solids had detectable bacteria. This finding suggests the use of dilution and/or low-cost formulations as a cause of bacterial growth. There was a statistically significant difference ( P = 0.0035) between the fraction of bacteria-positive samples with no detected antimicrobial agent (17%) and those containing an antimicrobial agent (7%). Fast food operations and grocery stores were more likely to have detectable bacteria in bulk-soap samples compared with convenience stores ( P < 0.05). Our findings underscore the risk to public health from use of refillable

Social uses of commercial soap operas: a conversation with Miguel Sabido.

PubMed

Singhal, A; Obregon, R

1999-01-01

This paper presents an interview with Miguel Sabido, a writer-producer-director of theater and soap operas in Mexico concerning the social uses of commercial soap operas. According to Sabido, television soap operas can play multiple roles in educating the public: 1) melodramatic soap operas represent a mediation between good and bad; 2) soap operas allow people to gossip on different characters, their dilemmas, and create a climate for social change, especially if it centers on key social issues; and 3) soap operas provide role models to emulate. Sabido stressed the importance of a theory-based method for producing drama and mentioned how theoreticians Bentley, Bandura, Maclean, and Jung influenced his writing and production of soap operas. According to Sabido, the social uses of commercial television are possible with socially responsible soap operas.

Presentation Extensions of the SOAP

NASA Technical Reports Server (NTRS)

Carnright, Robert; Stodden, David; Coggi, John

2009-01-01

A set of extensions of the Satellite Orbit Analysis Program (SOAP) enables simultaneous and/or sequential presentation of information from multiple sources. SOAP is used in the aerospace community as a means of collaborative visualization and analysis of data on planned spacecraft missions. The following definitions of terms also describe the display modalities of SOAP as now extended: In SOAP terminology, View signifies an animated three-dimensional (3D) scene, two-dimensional still image, plot of numerical data, or any other visible display derived from a computational simulation or other data source; a) "Viewport" signifies a rectangular portion of a computer-display window containing a view; b) "Palette" signifies a collection of one or more viewports configured for simultaneous (split-screen) display in the same window; c) "Slide" signifies a palette with a beginning and ending time and an animation time step; and d) "Presentation" signifies a prescribed sequence of slides. For example, multiple 3D views from different locations can be crafted for simultaneous display and combined with numerical plots and other representations of data for both qualitative and quantitative analysis. The resulting sets of views can be temporally sequenced to convey visual impressions of a sequence of events for a planned mission.

Handwashing with soap or alcoholic solutions? A randomized clinical trial of its effectiveness.

PubMed

Zaragoza, M; Sallés, M; Gomez, J; Bayas, J M; Trilla, A

1999-06-01

The effectiveness of an alcoholic solution compared with the standard hygienic handwashing procedure during regular work in clinical wards and intensive care units of a large public university hospital in Barcelona was assessed. A prospective, randomized clinical trial with crossover design, paired data, and blind evaluation was done. Eligible health care workers (HCWs) included permanent and temporary HCWs of wards and intensive care units. From each category, a random sample of persons was selected. HCWs were randomly assigned to regular handwashing (liquid soap and water) or handwashing with the alcoholic solution by using a crossover design. The number of colony-forming units on agar plates from hands printing in 3 different samples was counted. A total of 47 HCWs were included. The average reduction in the number of colony-forming units from samples before handwashing to samples after handwashing was 49.6% for soap and water and 88.2% for the alcoholic solution. When both methods were compared, the average number of colony-forming units recovered after the procedure showed a statistically significant difference in favor of the alcoholic solution (P <.001). The alcoholic solution was well tolerated by HCWs. Overall acceptance rate was classified as "good" by 72% of HCWs after 2 weeks use. Of all HCWs included, 9.3% stated that the use of the alcoholic solution worsened minor pre-existing skin conditions. Although the regular use of hygienic soap and water handwashing procedures is the gold standard, the use of alcoholic solutions is effective and safe and deserves more attention, especially in situations in which the handwashing compliance rate is hampered by architectural problems (lack of sinks) or nursing work overload.

Building an automated SOAP classifier for emergency department reports.

PubMed

Mowery, Danielle; Wiebe, Janyce; Visweswaran, Shyam; Harkema, Henk; Chapman, Wendy W

2012-02-01

Information extraction applications that extract structured event and entity information from unstructured text can leverage knowledge of clinical report structure to improve performance. The Subjective, Objective, Assessment, Plan (SOAP) framework, used to structure progress notes to facilitate problem-specific, clinical decision making by physicians, is one example of a well-known, canonical structure in the medical domain. Although its applicability to structuring data is understood, its contribution to information extraction tasks has not yet been determined. The first step to evaluating the SOAP framework's usefulness for clinical information extraction is to apply the model to clinical narratives and develop an automated SOAP classifier that classifies sentences from clinical reports. In this quantitative study, we applied the SOAP framework to sentences from emergency department reports, and trained and evaluated SOAP classifiers built with various linguistic features. We found the SOAP framework can be applied manually to emergency department reports with high agreement (Cohen's kappa coefficients over 0.70). Using a variety of features, we found classifiers for each SOAP class can be created with moderate to outstanding performance with F(1) scores of 93.9 (subjective), 94.5 (objective), 75.7 (assessment), and 77.0 (plan). We look forward to expanding the framework and applying the SOAP classification to clinical information extraction tasks. Copyright © 2011. Published by Elsevier Inc.

Manual dexterity aptitude testing: a soap carving study.

PubMed

Tang, Christopher G; Hilsinger, Raymond L; Cruz, Raul M; Schloegel, Luke J; Byl, Fred M; Rasgon, Barry M

2014-03-01

Currently there are few validated metrics for predicting surgical skill among otolaryngology residency applicants. To determine whether manual dexterity aptitude testing in the form of soap carving during otolaryngology residency interviews at Kaiser Permanente Medical Center Oakland predicts surgical skill at the time of graduation from otolaryngology residency programs. This study was conducted to determine how applicants with the best and worst soap carvings compared at the time of graduation with respect to various metrics including visuospatial ability and manual dexterity. Over the last 25 years, applicants to the residency program at Kaiser Permanente Oakland were required to carve soap during their residency interview. The 3 best and 3 worst soap carvings from 1990 through 2006 were determined. Of the individuals who carved those soaps, 62 qualified for the study and matriculated into otolaryngology residency programs. Surveys were sent to the 62 individuals' residency programs to evaluate those individuals on a 5-point Likert scale in various categories as well as to rank those individuals as being in the top 50% or bottom 50% of their graduating class. All else being equal, we hypothesized that applicants who had the manual dexterity and visuospatial skills to accurately carve a bar of soap would more likely possess the skills necessary to become a good surgeon. There was no difference between individuals with the best soap carvings and those with the worst soap carvings in all categories: cognitive knowledge, visuospatial ability, manual dexterity, decision making, and overall score (P > .10 for all categories). There was a 95% response rate, with 35 of 37 residency programs responding and 59 of 62 surveys returned. Manual dexterity aptitude testing in the form of soap carving does not appear to correlate with surgical skill at the time of graduation. Further studies need to be conducted to determine the role of manual dexterity and visuospatial

Rupture of vertical soap films

NASA Astrophysics Data System (ADS)

Rio, Emmanuelle

2014-11-01

Soap films are ephemeral and fragile objects. They tend to thin under gravity, which gives rise to the fascinating variations of colors at their interfaces but leads systematically to rupture. Even a child can create, manipulate and admire soap films and bubbles. Nevertheless, the reason why it suddenly bursts remains a mystery although the soap chosen to stabilize the film as well as the humidity of the air seem very important. One difficulty to study the rupture of vertical soap films is to control the initial solution. To avoid this problem we choose to study the rupture during the generation of the film at a controlled velocity. We have built an experiment, in which we measure the maximum length of the film together with its lifetime. The generation of the film is due to the presence of a gradient of surface concentration of surfactants at the liquid/air interface. This leads to a Marangoni force directed toward the top of the film. The film is expected to burst only when its weight is not balanced anymore by this force. We will show that this leads to the surprising result that the thicker films have shorter lifetimes than the thinner ones. It is thus the ability of the interface to sustain a surface concentration gradient of surfactants which controls its stability.

The importance of soap selection for routine hand hygiene in hospital.

PubMed Central

Ojajärvi, J.

1981-01-01

Five different types of liquid soap were studied in hospital wards, each during two months' use. Altogether 1306 finger print samples were taken from the hands of the staff by sampling twice a week and the acceptability of the soaps was measured by a questionnaire. During the use of different soaps only slight differences were found in the numbers of total bacteria or in the occurrence of Staph. aureus and gram-negative bacilli on the hands. During the use of the emulsion-type product studied, several persons who had dermatological problems had lower mean bacterial counts of the fingers than during the use of the other soaps. This soap was also favourably accepted by the staff. After over one year's use of pine oil soap and alcohol, the staff of the hospital was satisfied with the method. However, several persons with skin problems admitted to not using soap or alcohol. The considerable differences found in the acceptability of soaps imply that for use in hospital the choice of a soap acceptable to the nursing staff is important in promoting proper hand hygiene. PMID:7240731

Effective dilution of surfactants due to thinning of the soap film

NASA Astrophysics Data System (ADS)

Sane, Aakash; Mandre, Shreyas; Kim, Ildoo

2017-11-01

A flowing soap film is a system whose hydrodynamic properties can be affected by its thickness. Despite abundant experiments performed using soap films, few have examined the dependence of its physical as well as chemical properties with respect to its thickness. We investigate one such property - surface tension of the flowing film and delineate its dependence on the concentration of the soap solution and flow rate per unit width i.e. thickness of the soap film. Using our proposed method to measure the average surface tension in-situ over the whole soap film, we show that the surface tension increases by reducing the thickness of the film and by reducing the concentration of the soap solution. Our data suggests that thinning of the soap film is effectively diluting the solution. Thinning increases the adsorption of surfactants to the surfaces, but it decreases the total number of molecules per unit area. Our work brings new insight into the physics of soap films and we believe that this effective dilution due to thinning is a signature of the flowing soap films, whose surface concentration of surfactants is affected by the thickness.

Electrowetting of soap bubbles

NASA Astrophysics Data System (ADS)

Arscott, Steve

2013-07-01

A proof-of-concept demonstration of the electrowetting-on-dielectric of a sessile soap bubble is reported here. The bubbles are generated using a commercial soap bubble mixture—the surfaces are composed of highly doped, commercial silicon wafers covered with nanometer thick films of Teflon®. Voltages less than 40 V are sufficient to observe the modification of the bubble shape and the apparent bubble contact angle. Such observations open the way to inter alia the possibility of bubble-transport, as opposed to droplet-transport, in fluidic microsystems (e.g., laboratory-on-a-chip)—the potential gains in terms of volume, speed, and surface/volume ratio are non-negligible.

Critical assessment of the pH of children's soap.

PubMed

Mendes, Bruna Rafaela; Shimabukuro, Danielle Midori; Uber, Marjorie; Abagge, Kerstin Taniguchi

2016-01-01

To evaluate the pH value of children's antibacterial soaps and syndets used in children's baths and verify whether there is information regarding pH on the product label. Quantitative, cross-sectional, analytical observational study that included ninety soap samples, both in bar and liquid presentations, as follows: 67 children's soap (group 1), 17 antibacterial soaps (group 2), and 6 syndets (group 3). Each sample had its pH measured after 1% dilution. In addition to descriptive statistics, the Pearson-Yates chi-squared test and Student's t-tests were applied, considering the minimal significance level of 5%. The Wilcoxon-Mann-Whitney test, Fisher's exact test, and the Kruskal-Wallis test were used for inferential statistics. The pH levels varied considerably between liquid and bar presentations, with lower levels (4.4-7.9) found for the liquids (p<0.05). Syndets showed pH levels close to the ideal (slightly acid) and the antibacterial soaps showed the highest pH levels (up to 11.34) (p<0.05). Only two of the soaps included in the study had information about their pH levels on the product packaging. Knowledge of the pH of children's soap by doctors and users is important, considering the great pH variability found in this study. Moreover, liquid soaps, and especially syndets, are the most recommended for the sensitive skin of neonates and infants, in order to guarantee skin barrier efficacy. Copyright © 2016 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

Significance of Ca-soap formation for calcium absorption in the rat.

PubMed Central

Gacs, G; Barltrop, D

1977-01-01

The significance of calcium soap formation in the inhibition of calcium absorption has been studied in rats. 47Ca labelled soaps of fatty acids were introduced into the duodenum and the absorption of calcium measured after four hours in a whole body counter. The absorption of calcium was inversely correlated with the chain length of the fatty acid varying from 1% for Ca-stearate to 60% for Ca-hexanoate. Increasing the degree of unsaturation of the fatty acid was accompanied by increased calcium absorption. The availability of calcium for absorption from the soaps was correlated with their solubility in 1% aqueous Na-tauroglycocholate. The percentages of calcium as soap in the small intestine and the faeces after intragastric administration of calcium and fats were similar, which suggests that the faecal content of calcium soaps is an index of intestinal soap formation. Soap formation was negligible when CaCl2 was given with tristearate, triolaeate, or tridecanoate and no depression of calcium absorption was observed. Calcium absorption was markedly impaired by the addition of phosphates at a Ca/P ratio of 1:1 irrespective of the presence of neutral fats. Stearic acid resulted in significant soap formation and reduced calcium absorption. The degree of Ca-soap formation and the inhibition of calcium absorption were well correlated. The results suggest that, although calcium soap formation may markedly depress calcium absorption in the rat, no significant soap formation takes place when fats are given in the form of triglycerides. PMID:838405

Synthesis of Exotic Soaps in the Chemistry Laboratory

NASA Astrophysics Data System (ADS)

Phanstiel, Otto, IV; Dueno, Eric; Xianghong Wang, Queenie

1998-05-01

A variety of different triglyceride sources ranging from Vietnamese garlic oil to a local restaurant's grill sludge were saponified to generate a series of exotic soaps. Students did not quantify their results, but described their products in terms of color, texture and odor. Their results were compared with existing data on the triglyceride content for each source used (when possible). Soap texture seemed to be related to the degree of unsaturation present in the starting triglyceride. However, texture alterations due to occluded impurities could not be ruled out. In general, fats and oils high in saturated fats (butter) gave hard, chunky, and waxlike soaps, while those high in unsaturated fats gave flaky and easily crumbled soaps (olive, corn, peanut and sunflower oils). Soap color was not consistent with triglyceride unsaturation levels during the time frame studied. Odor changes were dramatic and were explained in terms of a change in chemical structure (i.e. conversion from an ester to a carboxylate salt). In general, the experiment was well received by students and stressed the importance of making precise qualitative observations during the experiment.

Sensitivities of Soap Solutions in Leak Detection

NASA Technical Reports Server (NTRS)

Stuck, D.; Lam, D. Q.; Daniels, C.

1985-01-01

Document describes method for determining minimum leak rate to which soap-solution leak detectors sensitive. Bubbles formed at smaller leak rates than previously assumed. In addition to presenting test results, document discusses effects of joint-flange configurations, properties of soap solutions, and correlation of test results with earlier data.

Stability Conditions and Mechanism of Cream Soaps: Effect of Polyols.

PubMed

Sagitani, Hiromichi; Komoriya, Masumi

2015-01-01

Fatty acids, fatty acid potassium soaps, polyols and water are essential ingredients for producing stable cream soaps. The solution behavior of the above four components system has been studied to elucidate the effect of four sorts of polyols (glycerol, 1,3-butylene glycol, polyethylene glycol 400 and dipropylene glycol) on the stability of cream soaps. It has been revealed that the lamellar liquid crystalline one-phase converted to a two-phase of a lamellar phase and an isotropic aqueous solution by the addition of a few percent of 1,3-butylene glycol, polyethylene glycol 400 and dipropylene glycol, whereas the lamellar one-phase was remained by about 50 wt% of glycerol in the aqueous solution. The X-ray data at room temperature showed that the existence of 1:1 acid soap (1:1 mole ratio of potassium soap/fatty acid) crystals in the 1,3-butylene glycol, polyethylene glycol 400 and dipropylene glycol systems, whereas that the coexistence of 1:1 acid soap crystal and a lamellar gel phase (swelled lamellar gel structure) in the glycerol system. The phase transition peaks from coagel to gel (Tgel) and from gel to liquid state (Tc) were appeared in the above four polyol systems by DSC measurements. It was confirmed from the combined data of SAXS and DSC that the existence of anhydrous 1:1 acid soap gels (or with small amount of bound water) in the all polyol systems, whereas the coexistence of the anhydrate gel and the swelled gel with a lot of intermediate water in the only glycerol system. This swelled gel structure would be contributed to stabilize the dispersed anhydrate acid soap crystals in cream soaps.

Doughnut-shaped soap bubbles.

PubMed

Préve, Deison; Saa, Alberto

2015-10-01

Soap bubbles are thin liquid films enclosing a fixed volume of air. Since the surface tension is typically assumed to be the only factor responsible for conforming the soap bubble shape, the realized bubble surfaces are always minimal area ones. Here, we consider the problem of finding the axisymmetric minimal area surface enclosing a fixed volume V and with a fixed equatorial perimeter L. It is well known that the sphere is the solution for V=L(3)/6π(2), and this is indeed the case of a free soap bubble, for instance. Surprisingly, we show that for V<αL(3)/6π(2), with α≈0.21, such a surface cannot be the usual lens-shaped surface formed by the juxtaposition of two spherical caps, but is rather a toroidal surface. Practically, a doughnut-shaped bubble is known to be ultimately unstable and, hence, it will eventually lose its axisymmetry by breaking apart in smaller bubbles. Indisputably, however, the topological transition from spherical to toroidal surfaces is mandatory here for obtaining the global solution for this axisymmetric isoperimetric problem. Our result suggests that deformed bubbles with V<αL(3)/6π(2) cannot be stable and should not exist in foams, for instance.

Doughnut-shaped soap bubbles

NASA Astrophysics Data System (ADS)

Préve, Deison; Saa, Alberto

2015-10-01

Soap bubbles are thin liquid films enclosing a fixed volume of air. Since the surface tension is typically assumed to be the only factor responsible for conforming the soap bubble shape, the realized bubble surfaces are always minimal area ones. Here, we consider the problem of finding the axisymmetric minimal area surface enclosing a fixed volume V and with a fixed equatorial perimeter L . It is well known that the sphere is the solution for V =L3/6 π2 , and this is indeed the case of a free soap bubble, for instance. Surprisingly, we show that for V <α L3/6 π2 , with α ≈0.21 , such a surface cannot be the usual lens-shaped surface formed by the juxtaposition of two spherical caps, but is rather a toroidal surface. Practically, a doughnut-shaped bubble is known to be ultimately unstable and, hence, it will eventually lose its axisymmetry by breaking apart in smaller bubbles. Indisputably, however, the topological transition from spherical to toroidal surfaces is mandatory here for obtaining the global solution for this axisymmetric isoperimetric problem. Our result suggests that deformed bubbles with V <α L3/6 π2 cannot be stable and should not exist in foams, for instance.

Bow and Oblique Shock Formation in Soap Film

NASA Astrophysics Data System (ADS)

Kim, Ildoo; Mandre, Shreyas; Sane, Aakash

2015-11-01

In recent years, soap films have been exploited primarily to approximate two-dimensional flows while their three-dimensional character is relatively unattended. An example of the three-dimensional character of the flow in a soap film is the observed Marangoni shock wave when the flow speed exceeds the wave speed. In this study, we investigated the formation of bow and oblique shocks in soap films generated by wedges with different deflection angles. When the wedge deflection angle is small and the film flows fast, oblique shocks are observed. When the oblique shock cannot exists, bow shock is formed upstream the wedge. We characterized the oblique shock angle as a function of the wedge deflection angle and the flow speed, and we also present the criteria for transition between bow and oblique Marangoni shocks in soap films.

Soap Bubble Spectra.

ERIC Educational Resources Information Center

Siddons, Colin

1984-01-01

Describes an apparatus (called the "Rainbow Cup") used for demonstrating the colored rings produced by constructive interference in soap films. Discusses construction of the Rainbow Cup and gives hints for its use in the classroom, especially in relation to classroom humidity. (JM)

Colorful Demos with a Long-Lasting Soap Bubble.

ERIC Educational Resources Information Center

Behroozi, F.; Olson, D. W.

1994-01-01

Describes several demonstrations that feature interaction of light with soap bubbles. Includes directions about how to produce a long-lasting stationary soap bubble with an easily changeable size and describes the interaction of white light with the bubble. (DDR)

Pro-development soap operas: a novel approach to development communication.

PubMed

Brown, W J; Singhal, A; Rogers, E M

1989-01-01

Soap operas have their roots in 18th century English romance novels. These evolved into serialized radio dramas. In their current form, they were developed primarily to attract large audiences in order to sell consumer products. Hence the name soap which refers to the soap manufacturers who commonly advertise on such programs. In the world of soap operas there are 2 kinds. Those that function primarily to entertain and sell consumer products, and those that primarily entertain, but infuse positive social messages. The former are found everywhere, but are the only kind in America. The latter are found exclusively in developing countries. American soap operas have conveyed pro-social messages in the past, but they differ fundamentally from pro-development soap operas in their theoretical foundations. American soap operas are created by people who want to sell consumer goods. Development soap operas are created by people who want to convey pro-social messages that will aid their country's development. Both must be popular in order to be successful, but the former lack moral coherency, are unrealistic, erode values, and are created through a process of a theoretical development; while the latter have moral coherency, are realistic, promote values, and are created through a process of theoretical development. The 1st pro-development soap opera was Ven Conmigo (Come With Me) and was produced in Mexico between 1975-76. Its primary purpose was to increase adult literacy. During the year it ran, applicants at adult literacy centers rose by 600,000 or 63% compared to 7% the year before, and 2% the year after. The 2nd pro-development soap opera was Acompaname (Accompany Me) and it primary purpose was to promote family planning. It ran from 1977-78 and during that time the number of family planning adopters rose by 560,000 and contraceptive sale sin Mexico rose sharply. The question of what are pro-social messages and who should control them must be answered by each country in

Chemistry in Soap Bubbles.

ERIC Educational Resources Information Center

Lee, Albert W. M.; Wong, A.; Lee, H. W.; Lee, H. Y.; Zhou, Ning-Huai

2002-01-01

Describes a laboratory experiment in which common chemical gases are trapped inside soap bubbles. Examines the physical and chemical properties of the gases such as relative density and combustion. (Author/MM)

Hydrodynamics of soap films probed by two-particle microrheology

NASA Astrophysics Data System (ADS)

Prasad, Vikram; Weeks, Eric R.

2007-11-01

A soap film consists of a thin water layer that is separated from two bulk air phases above and below it by surfactant monolayers. The flow fields in the soap film created in response to a perturbation depend on coupling between these different phases, the exact nature of which is unknown. In order to determine this coupling, we use polystyrene spheres as tracer particles and track their diffusive motions in the soap film. The correlated Brownian motion of pairs of particles (two-particle microrheology) maps out the flow field, and provides a measure of the surface viscosity of the soap film as well. This measured surface viscosity agrees well with the value obtained from self diffusion of single particles (one-particle microrheology) in the film.

Soap bubbles in analytical chemistry. Conductometric determination of sub-parts per million levels of sulfur dioxide with a soap bubble.

PubMed

Kanyanee, Tinakorn; Borst, Walter L; Jakmunee, Jaroon; Grudpan, Kate; Li, Jianzhong; Dasgupta, Purnendu K

2006-04-15

Soap bubbles provide a fascinating tool that is little used analytically. With a very low liquid volume to surface area ratio, a soap bubble can potentially provide a very useful interface for preconcentration where mass transfer to an interfacial surface is important. Here we use an automated system to create bubbles of uniform size and film thickness. We utilize purified Triton-X 100, a nonionic surfactant, to make soap bubbles. We use such bubbles as a gas-sampling interface. Incorporating hydrogen peroxide into the bubble provides a system where electrical conductance increases as the bubble is exposed to low concentrations of sulfur dioxide gas. We theoretically derive the conductance of a hollow conducting spherical thin film with spherical cap electrodes. We measure the film thickness by incorporating a dye in the bubble making solution and laser transmission photometry and find that it agrees well with the geometrically computed thickness. With the conductance of the bubble-making soap solution being measured by conventional methods, we show that the measured values of the bubble conductance with known bubble and electrode dimensions closely correspond to the theoretically computed value. Finally, we demonstrate that sub-ppm levels of SO(2) can readily be detected by the conductivity change of a hydrogen peroxide-doped soap bubble, measured in situ, when the gas flows around the bubble.

The Systems SOAP Note: A Systems Learning Tool.

PubMed

Mitsuishi, Fumi; Young, John Q; Leary, Mark; Dilley, James; Mangurian, Christina

2016-02-01

Systems-based practice (SBP) is the only Accreditation Council for Graduate Medical Education (ACGME) competency concerned with public health and is relatively neglected in residency curricula. A tool was developed and pilot-tested to improve SBP learning on inpatient psychiatry rotations. A four-step approach was used: (1) literature review, (2) expert consultation, (3) tool development, and (4) pilot testing on four cases and evaluation for completion time and preliminary efficacy. Out of 51 SBP articles, six (12%) focused on psychiatric residency programs, and none had a practical SBP learning tool. The "systems SOAP (subjective, objective, assessment, plan) note" (S-SOAP) was structured after a clinical SOAP note and was easy to use (mean completion time = 60 min), and residents self-reported more insight into systems issues. The S-SOAP tool was effectively integrated into clinical experience and provided insight into systemic complexities. Future research should assess SBP knowledge acquisition after the use of such tools.

Nosocomial Serratia marcescens infections associated with extrinsic contamination of a liquid nonmedicated soap.

PubMed

Sartor, C; Jacomo, V; Duvivier, C; Tissot-Dupont, H; Sambuc, R; Drancourt, M

2000-03-01

To determine the role of nonmedicated soap as a source of Serratia marcescens nosocomial infections (NIs) in hospital units with endemic S marcescens NI and to examine the mechanisms of soap colonization. University-affiliated tertiary-care hospitals. A prospective case-control study and an environmental investigation were performed to assess the relationship between S marcescens NIs in hospital units and S marcescens-contaminated soap. Soap-bottle use and handwashing practices were reviewed. Cultures of healthcare workers' (HCWs) hands were obtained before and after hand washing with soap. 5 of 7 hospital units with S marcescens NIs had soap bottles contaminated with S marcescens, compared to 1 of 14 other units (P=.006). After hand washing with an S marcescens-contaminated soap pump, HCWs' hands were 54 times more likely to be contaminated with S marcescens (P<.001). Extrinsic contamination of a non-medicated liquid soap by S marcescens resulted in handborne transmission of S marcescens NIs by HCWs in our setting. This finding led to the application of strict guidelines for nonmedicated soap use and to the reinforcement of alcoholic hand disinfection.

Health: the soap opera version.

PubMed

Harris, C

1993-01-01

Watching soap opera is a favorite pastime of millions of Egyptians. Since the spring of 1992, the soap opera "The Family House" has reached audiences with messages on AIDS, drugs, child spacing, home accidents, and hygiene. The shows are the brainchild of the Director of the Center for Development Communication (CDC) in Egypt, Dr. El Kamel; the shows capture the novel and unique concept of both the communication of information and entertainment. Between 1983 and 1990, the CDC has been creating 130 short soap opera episodes on subjects such as the prevention of dehydration from diarrhea and the use of oral rehydration salt (ORS) packets to save children's lives. The ORS episodes were 15 minutes in length and showed the dramatic tension between a baby suffering from diarrhea and the mother's helping to overcome the difficulty. Surveys conducted in 1983 and 1986 on knowledge, attitudes, and practices found that in 1986 98% knew about ORS and 70% had used it compared with 3% knowledge and 50% practice in 1983. "The Family House" will be similar but expand on the number of issues considered and will pretest audience knowledge, attitudes, and practice before and after airing on specific issues. This soap opera also will be the first to be a daily series with an unending story. "The main character is Amina, who is an artisan in her late 40s who raised 4 children by herself." The series of 45-minute long shows will depict urban and rural settings and everyday Egyptian culture: language, clothing, life styles, and moral standards. Distribution is anticipated for other Arabic countries in Africa and the Middle East, which already air many Egyptian television series.

The essential SOAP note in an EHR age.

PubMed

Pearce, Patricia F; Ferguson, Laurie Anne; George, Gwen S; Langford, Cynthia A

2016-02-18

This article reviews the traditional Subjective, Objective, Assessment, and Plan (SOAP) note documentation format. The information in the SOAP note is useful to both providers and students for history taking and physical exam, and highlights the importance of including critical documentation details with or without an electronic health record.

Gravity-driven soap film dynamics in subcritical regimes

NASA Astrophysics Data System (ADS)

Auliel, M. I.; Castro, F.; Sosa, R.; Artana, G.

2015-10-01

We undertake the analysis of soap-film dynamics with the classical approach of asymptotic expansions. We focus our analysis in vertical soap film tunnels operating in subcritical regimes with elastic Mach numbers Me=O(10-1) . Considering the associated set of nondimensional numbers that characterize this flow, we show that the flow behaves as a two-dimensional (2D) divergence free flow with variable mass density. When the soap film dynamics agrees with that of a 2D and almost constant mass density flow, the regions where the second invariant of the velocity gradient is non-null correspond to regions where the rate of change of film thickness is non-negligible.

Quantitative assessment of risk reduction from hand washing with antibacterial soaps.

PubMed

Gibson, L L; Rose, J B; Haas, C N; Gerba, C P; Rusin, P A

2002-01-01

The Centers for Disease Control and Prevention have estimated that there are 3,713,000 cases of infectious disease associated with day care facilities each year. The objective of this study was to examine the risk reduction achieved from using different soap formulations after diaper changing using a microbial quantitative risk assessment approach. To achieve this, a probability of infection model and an exposure assessment based on micro-organism transfer were used to evaluate the efficacy of different soap formulations in reducing the probability of disease following hand contact with an enteric pathogen. Based on this model, it was determined that the probability of infection ranged from 24/100 to 91/100 for those changing diapers of babies with symptomatic shigellosis who used a control product (soap without an antibacterial ingredient), 22/100 to 91/100 for those who used an antibacterial soap (chlorohexadine 4%), and 15/100 to 90/100 for those who used a triclosan (1.5%) antibacterial soap. Those with asymptomatic shigellosis who used a non-antibacterial control soap had a risk between 49/100,000 and 53/100, those who used the 4% chlorohexadine-containing soap had a risk between 43/100,000 and 51/100, and for those who used a 1.5% triclosan soap had a risk between 21/100,000 and 43/100. The adequate washing of hands after diapering reduces risk and can be further reduced by a factor of 20% by the use of an antibacterial soap. Quantitative risk assessment is a valuable tool in the evaluation of household sanitizing agents and low risk outcomes.

Ecological effects of a deodorant and a plain soap upon human skin bacteria.

PubMed Central

Bibel, D. J.

1977-01-01

The effects of a commercial trichlorocarbanilide-containing deodorant soap and a commercial plain soap upon the cutaneous flora of individuals were compared. Using a cross-over design, 21 volunteers (10 women and 11 men) washed their forearms at least once a day with one soap for 3 weeks and then switched soaps for another 4 weeks use. By analysis of variance no significant difference in total colony counts was noted among individuals in their use of the two soaps. With the exception of individual variation, neither sequence of use, sex, nor any combination was influential. However, in 20 of 21 subjects an alteration in the composition of skin flora was observed. The deodorant soap, which in six cases increased total flora, tended to reduce or eliminate diphtheroids in 12 to 17 carriers (71%). Fewer kinds of bacteria were also noted. More Staphylococcus epidermidis was seen with the plain soap, but washing with the deodorant soap seemed to favour Acinetobacter calcoaceticus and Micrococcus luteus. The impact of this alteration and the use of total counts to measure effectiveness of deodorant soaps were brought into question. PMID:264493

The Marangoni convection induced by acetone desorption from the falling soap film

NASA Astrophysics Data System (ADS)

Sha, Yong; Li, Zhangyun; Wang, Yongyi; Huang, Jiali

2012-05-01

By means of the falling soap film tunnel and the Schlieren optical method, the Marangoni convection were observed directly in the immediate interfacial neighborhood during the desorption process of acetone from the falling soap film. Moreover, the hydraulic characteristics of the falling soap film tunnel, the acetone concentration, the surface tension of the soap liquid and the mass transfer has been investigated in details through the experimental or theoretical method.

Laser Soap Fountain

ERIC Educational Resources Information Center

Foley, Tyler; Pegram, Matthew; Jenkins, Zachary; Hester, Brooke C.; Burris, Jennifer L.

2015-01-01

We have developed an eye-catching demonstration that showcases a variety of physics topics from total internal reflection to electrostatics to non-Newtonian fluid dynamics, including the Kaye effect. The essential components of the demonstration include a vertical stream of liquid soap in which a laser pointer is internally reflected, and which…

Cylinder wakes in flowing soap films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vorobieff, P.; Ecke, R.E.; Vorobieff, P.

1999-09-01

We present an experimental characterization of cylinder wakes in flowing soap films. From instantaneous velocity and thickness fields, we find the vortex-shedding frequency, mean-flow velocity, and mean-film thickness. Using the empirical relationship between the Reynolds and Strouhal numbers obtained for cylinder wakes in three dimensions, we estimate the effective soap-film viscosity and its dependence on film thickness. We also compare the decay of vorticity with that in a simple Rankine vortex model with a dissipative term to account for air drag. [copyright] [ital 1999] [ital The American Physical Society

Bacterial hand contamination and transfer after use of contaminated bulk-soap-refillable dispensers.

PubMed

Zapka, Carrie A; Campbell, Esther J; Maxwell, Sheri L; Gerba, Charles P; Dolan, Michael J; Arbogast, James W; Macinga, David R

2011-05-01

Bulk-soap-refillable dispensers are prone to extrinsic bacterial contamination, and recent studies demonstrated that approximately one in four dispensers in public restrooms are contaminated. The purpose of this study was to quantify bacterial hand contamination and transfer after use of contaminated soap under controlled laboratory and in-use conditions in a community setting. Under laboratory conditions using liquid soap experimentally contaminated with 7.51 log(10) CFU/ml of Serratia marcescens, an average of 5.28 log(10) CFU remained on each hand after washing, and 2.23 log(10) CFU was transferred to an agar surface. In an elementary-school-based field study, Gram-negative bacteria on the hands of students and staff increased by 1.42 log(10) CFU per hand (26-fold) after washing with soap from contaminated bulk-soap-refillable dispensers. In contrast, washing with soap from dispensers with sealed refills significantly reduced bacteria on hands by 0.30 log(10) CFU per hand (2-fold). Additionally, the mean number of Gram-negative bacteria transferred to surfaces after washing with soap from dispensers with sealed-soap refills (0.06 log(10) CFU) was significantly lower than the mean number after washing with contaminated bulk-soap-refillable dispensers (0.74 log(10) CFU; P < 0.01). Finally, significantly higher levels of Gram-negative bacteria were recovered from students (2.82 log(10) CFU per hand) than were recovered from staff (2.22 log(10) CFU per hand) after washing with contaminated bulk soap (P < 0.01). These results demonstrate that washing with contaminated soap from bulk-soap-refillable dispensers can increase the number of opportunistic pathogens on the hands and may play a role in the transmission of bacteria in public settings.

Mild soaps and radiotherapy: a survey of the UK public to identify brands of soap considered mild and analysis of these to ascertain suitability for recommendation in radiotherapy departments.

PubMed

Robertson, K; Brown, P

2011-05-01

Cancer agencies recommend that patients use mild soap when undergoing external beam radiotherapy to minimise skin reactions. They define 'mild soap' as non-alkaline, lanolin free, unperfumed soap with a neutral pH. This study aimed to identify which soaps the UK public perceive as mild and ascertain if these were clinically mild and could potentially be recommended within radiotherapy departments. A survey of 237 participants identified eight top brands of mild soap, which were then tested for pH and analysed for potential irritants. All soaps were lanolin free and non-alkaline, with Simple and Johnson's the closest to pH 5.5. All contained fragrances except Simple and E45. Dove, Pears and Imperial Leather contained the highest concentration of fragrances. All soaps except E45 contained potential irritants. Only Simple and E45 fit the cancer agencies' definition of mild soap and could therefore be recommended for radiotherapy patients. Future research should identify current practices and recommendations in the UK as anecdotal evidence suggests large variations in skin care advice. Further scientific analysis could potentially identify cheaper brands that fit the definition of 'mild'. UK recommendations should be standardised and consistent with best practice to reduce skin reaction severity in radiotherapy patients. © 2010 Blackwell Publishing Ltd.

9. 5TH FLOOR, INTERIOR DETAIL TO EAST OF SOAP BIN ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. 5TH FLOOR, INTERIOR DETAIL TO EAST OF SOAP BIN No. 4: UPPER SCREWS MOVED SOAP CHIPS HORIZONTALLY FROM BIN TO BIN; LOWER LEFT-AND RIGHT-HAND SCREWS MOVED CHIPS TO CHUTE LEADING TO 3RD FLOOR SOAP MILLS - Colgate & Company Jersey City Plant, Building No. B-14, 54-58 Grand Street, Jersey City, Hudson County, NJ

Guanidine Soaps As Vehicles For Coating Ceramic Fibers

NASA Technical Reports Server (NTRS)

Philipp, Warren H.; Veitch, Lisa C.; Jaskowiak, Martha H.

1994-01-01

Soaps made from strong organic base guanidine and organic fatty acids serve as vehicles and binders for coating ceramic fibers, various smooth substrates, and other problematic surfaces with thin precious-metal or metal-oxide films. Films needed to serve as barriers to diffusion in fiber/matrix ceramic composite materials. Guanidine soaps entirely organic and burn off, leaving no residues.

Comparing Architectural Styles for Service-Oriented Architectures - a REST vs. SOAP Case Study

NASA Astrophysics Data System (ADS)

Becker, Jörg; Matzner, Martin; Müller, Oliver

Two architectural styles are currently heavily discussed regarding the design of service-oriented architectures (SOA). Within this chapter we have compared those two alternative styles - the SOAP-style with procedural designs similar to remote procedure calls and the REST-style with loosely coupled services similar to resources of the World Wide Web. We introduce the case of a business network consisting of manufacturers and service providers of the electronics industry for deriving a set of requirements towards a specific SOA implementation. For each architectural style we present a concrete SOA design and evaluate it against the defined set of requirements.

40 CFR 417.10 - Applicability; description of the soap manufacturing by batch kettle subcategory.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 29 2014-07-01 2012-07-01 true Applicability; description of the soap... PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by Batch Kettle Subcategory § 417.10 Applicability; description of the soap...

40 CFR 417.10 - Applicability; description of the soap manufacturing by batch kettle subcategory.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 30 2012-07-01 2012-07-01 false Applicability; description of the soap... PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by Batch Kettle Subcategory § 417.10 Applicability; description of the soap...

40 CFR 417.10 - Applicability; description of the soap manufacturing by batch kettle subcategory.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 30 2013-07-01 2012-07-01 true Applicability; description of the soap... PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by Batch Kettle Subcategory § 417.10 Applicability; description of the soap...

False-positive cryptococcal antigen latex agglutination caused by disinfectants and soaps.

PubMed Central

Blevins, L B; Fenn, J; Segal, H; Newcomb-Gayman, P; Carroll, K C

1995-01-01

Five disinfectants or soaps were tested to determine if any could be responsible for false-positive results obtained with the Latex-Crypto Antigen Detection System kit (Immuno-Mycologics, Inc., Norman, Okla.). Three disinfectants or soaps (Derma soap, 7X, and Bacdown) produced false-positive agglutination after repeated washing of ring slides during testing of a known negative cerebrospinal fluid specimen. PMID:7650214

An Experimental Study of the Effect of Viscosity on Bouncing Soap Droplets onto a Horizontal Soap Film

NASA Astrophysics Data System (ADS)

Gunter, Amy-Lee; Ng, Hoi Dick

2012-11-01

This experimental study aims to investigate the phenomenon of a bouncing soap droplet on a horizontal soap film, and how this behavior is affected by variations in the glycerol content of the solution for both the droplet and film. Direct visualization of the bouncing dynamics using high-speed photography allows determination of droplet size and rebound height as the viscosity is varied. In addition, the upper and lower limits of the mixture composition at which the viscosity of the fluid prevents the droplet from bouncing are determined. A thorough examination of this fluid trampoline was recently conducted by Gilet and Bush, the focus of which was to compare the effect of vibration in the soap film [T. Gilet and J.W.M. Bush, J. Fluid Mech. 625: 167-203, 2009]. A small amount of attention was given to the effect of viscosity changes in the droplet and film, and this work aims to expand on those findings. This work is supported by the Natural Sciences and Engineering Research Council of Canada (NSERC).

Sound and vision: visualization of music with a soap film

NASA Astrophysics Data System (ADS)

Gaulon, C.; Derec, C.; Combriat, T.; Marmottant, P.; Elias, F.

2017-07-01

A vertical soap film, freely suspended at the end of a tube, is vibrated by a sound wave that propagates in the tube. If the sound wave is a piece of music, the soap film ‘comes alive’: colours, due to iridescences in the soap film, swirl, split and merge in time with the music (see the snapshots in figure 1 below). In this article, we analyse the rich physics behind these fascinating dynamical patterns: it combines the acoustic propagation in a tube, the light interferences, and the static and dynamic properties of soap films. The interaction between the acoustic wave and the liquid membrane results in capillary waves on the soap film, as well as non-linear effects leading to a non-oscillatory flow of liquid in the plane of the film, which induces several spectacular effects: generation of vortices, diphasic dynamical patterns inside the film, and swelling of the soap film under certain conditions. Each of these effects is associated with a characteristic time scale, which interacts with the characteristic time of the music play. This article shows the richness of those characteristic times that lead to dynamical patterns. Through its artistic interest, the experiments presented in this article provide a tool for popularizing and demonstrating science in the classroom or to a broader audience.

Light guiding properties of soap films

NASA Astrophysics Data System (ADS)

Emile, Janine; Emile, Olivier; Casanova, Federico

2013-02-01

The injection of a laser beam from the side in a horizontal free-standing draining soap film is reported. We observe the self-deflection of the beam that varies in a random way. The film thinning is affected by the injection and depends on the polarization of the light beam, not on the laser power. The liquid in the soap film is ejected towards the meniscus, without modifying its molecular structure. Besides, this injection seems to stabilize the film near the light beam propagation and to destabilize the film in the other zones. Consequences and applications are then discussed.

Elasticity of a soap film junction

NASA Astrophysics Data System (ADS)

Elias, F.; Janiaud, E.; Bacri, J.-C.; Andreotti, B.

2014-03-01

We investigate the elasticity of an isolated, threefold junction of soap films (Plateau border), which displays static undulations when liquid rapidly flows into it. By analyzing the shape of the Plateau border (thickness R and transverse displacement) as a function of the liquid flow rate Q, we show experimentally and theoretically that the elasticity of the Plateau border is dominated by the bending of the soap films pulling on the Plateau border. In this asymptotic regime, the undulation wavelength obeys the scaling law ˜Q2 R-2 and the decay length ˜Q2 R-4.

Columnar to Nematic Mesophase Transition: Binary Mixtures of Unlike Copper Soaps

NASA Astrophysics Data System (ADS)

Seghrouchni, R.; Skoulios, A.

1995-10-01

Copper (II) soaps are known to produce columnar mesophases at high temperature. The polar groups of the soap molecules are stacked over one another within columns surrounded by the alkyl chains in a disordered conformation and laterally arranged according to a two-dimensional hexagonal lattice. The present work studies the mesomorphic behaviour of binary mixtures of copper soaps using differential scanning calorimetry, polarizing microscopy, and X-ray diffraction. When the soaps are of comparable molecular sizes the mixtures are homogeneous and columnar at all compositions. The columns of the two soaps, remaining intact in the mixture, are distributed randomly on the nodes of a hexagonal Bravais lattice. Crystallographic homogeneity is obtained by transfer of methylene groups from cell to cell. When, on the other hand, the soaps are different enough in molecular sizes, the columnar structure of the mixtures is interrupted in the middle range of compositions for the benefit of a nematic one. The transfer of methylene groups gets indeed harder to achieve and the distortion of the hexagonal units cells becomes important. The columnar to nematic phase transition is discussed on a molecular and a topological level.

Foam structure :from soap froth to solid foams.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kraynik, Andrew Michael

2003-01-01

The properties of solid foams depend on their structure, which usually evolves in the fluid state as gas bubbles expand to form polyhedral cells. The characteristic feature of foam structure-randomly packed cells of different sizes and shapes-is examined in this article by considering soap froth. This material can be modeled as a network of minimal surfaces that divide space into polyhedral cells. The cell-level geometry of random soap froth is calculated with Brakke's Surface Evolver software. The distribution of cell volumes ranges from monodisperse to highly polydisperse. Topological and geometric properties, such as surface area and edge length, of themore » entire foam and individual cells, are discussed. The shape of struts in solid foams is related to Plateau borders in liquid foams and calculated for different volume fractions of material. The models of soap froth are used as templates to produce finite element models of open-cell foams. Three-dimensional images of open-cell foams obtained with x-ray microtomography allow virtual reconstruction of skeletal structures that compare well with the Surface Evolver simulations of soap-froth geometry.« less

Waterflooding employing surfactants derived from metallic soaps

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, S.A.

1975-12-16

A waterflooding process is described in which a petroleum oil containing divalent metal soaps is contacted with an inorganic acid in order to convert the soaps to the corresponding organic acids. The organic acids thus obtained may be injected into the reservoir followed by an aqueous alkaline solution. Alternatively, the organic acids may be contacted with an aqueous solution in order to convert the acids to the corresponding surface-active monovalent salts, which may be then injected into the reservoir. (4 claims)

Antibacterial properties of soap containing some fatty acid esters.

PubMed

Pandey, N K; Natraj, C V; Kalle, G P; Nambudiry, M E

1985-02-01

Synopsis Chemical microbial inhibitors compatible with formulations of soaps and deodorant perfumes are more effective if they are substantive to the skin. However, highly effective inhibitors are toxic and their substantivity on skin may accentuate the toxicity. Natural compounds such as short to medium chain fatty acids and their derivatives, which are known to be germicidal, offer a viable alternative to chemical inhibitors. We report here the synthesis of sodium 2-lauroyloxy propionate and an in vivo method to test its substantivity on skin following its incorporation in soaps. Among several compounds tested, sodium 2-lauroyloxy propionate was found to be highly substantive in soap formulation.

Antimicrobial Activity of Medicated Soaps Commonly Used By Dar es Salaam Residents in Tanzania.

PubMed

Mwambete, K D; Lyombe, F

2011-01-01

An in vitro evaluation of the anti-microbial activity of medicated soaps was conducted using ditch-plate and hand washing techniques. Strains of reference microbes namely Candida albicans (ATCC90028), Staphylococcus aureus (ATCC25923), Pseudomonas aureginosa (ATCC27853) and Escherichia coli (ATCC25922) were tested at three different soaps' concentrations (1.0, 4.0 and 8.0 mg/ml). A total of 16 medicated soaps were assayed for their antimicrobial efficacy. Of these, 13 were medicated and 3 non-medicated soaps, which served as control. Ciprofloxacin and ketaconazole were employed as positive controls. Label disclosure for the soaps' ingredients and other relevant information were absorbed. The most common antimicrobial active ingredients were triclosan, trichloroxylenol and trichlorocarbanilide. ANOVA for means of zones of inhibition revealed variability of antimicrobial activity among the medicated soaps. Positive correlation (r=0.318; P<0.01) between zones of inhibition and soaps' concentrations was evidenced. Hand washing frequencies positively correlated with microbial counts. Roberts(®) soap exhibited the largest zone of inhibition (34 mm) on S. aureus. Candida albicans was the least susceptible microbe. Regency(®) and Dalan(®) exhibited the least zone of inhibition on the tested bacteria. Protex(®), Roberts(®), Family(®) and Protector(®) were equally effective (P<0.01) against S. aureus. In conclusion, majority of the assayed medicated soaps have satisfactory antibacterial activity; though lack antifungal effect with exception of Linda(®) liquid soap. The hand washing technique has proved to be inappropriate for evaluation of soaps' antimicrobial efficacy due to presence of the skin microflora.

On the shape of giant soap bubbles.

PubMed

Cohen, Caroline; Darbois Texier, Baptiste; Reyssat, Etienne; Snoeijer, Jacco H; Quéré, David; Clanet, Christophe

2017-03-07

We study the effect of gravity on giant soap bubbles and show that it becomes dominant above the critical size [Formula: see text], where [Formula: see text] is the mean thickness of the soap film and [Formula: see text] is the capillary length ([Formula: see text] stands for vapor-liquid surface tension, and [Formula: see text] stands for the liquid density). We first show experimentally that large soap bubbles do not retain a spherical shape but flatten when increasing their size. A theoretical model is then developed to account for this effect, predicting the shape based on mechanical equilibrium. In stark contrast to liquid drops, we show that there is no mechanical limit of the height of giant bubble shapes. In practice, the physicochemical constraints imposed by surfactant molecules limit the access to this large asymptotic domain. However, by an exact analogy, it is shown how the giant bubble shapes can be realized by large inflatable structures.

Bacterial Hand Contamination and Transfer after Use of Contaminated Bulk-Soap-Refillable Dispensers▿†

PubMed Central

Zapka, Carrie A.; Campbell, Esther J.; Maxwell, Sheri L.; Gerba, Charles P.; Dolan, Michael J.; Arbogast, James W.; Macinga, David R.

2011-01-01

Bulk-soap-refillable dispensers are prone to extrinsic bacterial contamination, and recent studies demonstrated that approximately one in four dispensers in public restrooms are contaminated. The purpose of this study was to quantify bacterial hand contamination and transfer after use of contaminated soap under controlled laboratory and in-use conditions in a community setting. Under laboratory conditions using liquid soap experimentally contaminated with 7.51 log10 CFU/ml of Serratia marcescens, an average of 5.28 log10 CFU remained on each hand after washing, and 2.23 log10 CFU was transferred to an agar surface. In an elementary-school-based field study, Gram-negative bacteria on the hands of students and staff increased by 1.42 log10 CFU per hand (26-fold) after washing with soap from contaminated bulk-soap-refillable dispensers. In contrast, washing with soap from dispensers with sealed refills significantly reduced bacteria on hands by 0.30 log10 CFU per hand (2-fold). Additionally, the mean number of Gram-negative bacteria transferred to surfaces after washing with soap from dispensers with sealed-soap refills (0.06 log10 CFU) was significantly lower than the mean number after washing with contaminated bulk-soap-refillable dispensers (0.74 log10 CFU; P < 0.01). Finally, significantly higher levels of Gram-negative bacteria were recovered from students (2.82 log10 CFU per hand) than were recovered from staff (2.22 log10 CFU per hand) after washing with contaminated bulk soap (P < 0.01). These results demonstrate that washing with contaminated soap from bulk-soap-refillable dispensers can increase the number of opportunistic pathogens on the hands and may play a role in the transmission of bacteria in public settings. PMID:21421792

Alternative Hand Contamination Technique To Compare the Activities of Antimicrobial and Nonantimicrobial Soaps under Different Test Conditions▿

PubMed Central

Fuls, Janice L.; Rodgers, Nancy D.; Fischler, George E.; Howard, Jeanne M.; Patel, Monica; Weidner, Patrick L.; Duran, Melani H.

2008-01-01

Antimicrobial hand soaps provide a greater bacterial reduction than nonantimicrobial soaps. However, the link between greater bacterial reduction and a reduction of disease has not been definitively demonstrated. Confounding factors, such as compliance, soap volume, and wash time, may all influence the outcomes of studies. The aim of this work was to examine the effects of wash time and soap volume on the relative activities and the subsequent transfer of bacteria to inanimate objects for antimicrobial and nonantimicrobial soaps. Increasing the wash time from 15 to 30 seconds increased reduction of Shigella flexneri from 2.90 to 3.33 log10 counts (P = 0.086) for the antimicrobial soap, while nonantimicrobial soap achieved reductions of 1.72 and 1.67 log10 counts (P > 0.6). Increasing soap volume increased bacterial reductions for both the antimicrobial and the nonantimicrobial soaps. When the soap volume was normalized based on weight (∼3 g), nonantimicrobial soap reduced Serratia marcescens by 1.08 log10 counts, compared to the 3.83-log10 reduction caused by the antimicrobial soap (P < 0.001). The transfer of Escherichia coli to plastic balls following a 15-second hand wash with antimicrobial soap resulted in a bacterial recovery of 2.49 log10 counts, compared to the 4.22-log10 (P < 0.001) bacterial recovery on balls handled by hands washed with nonantimicrobial soap. This indicates that nonantimicrobial soap was less active and that the effectiveness of antimicrobial soaps can be improved with longer wash time and greater soap volume. The transfer of bacteria to objects was significantly reduced due to greater reduction in bacteria following the use of antimicrobial soap. PMID:18441107

Alternative hand contamination technique to compare the activities of antimicrobial and nonantimicrobial soaps under different test conditions.

PubMed

Fuls, Janice L; Rodgers, Nancy D; Fischler, George E; Howard, Jeanne M; Patel, Monica; Weidner, Patrick L; Duran, Melani H

2008-06-01

Antimicrobial hand soaps provide a greater bacterial reduction than nonantimicrobial soaps. However, the link between greater bacterial reduction and a reduction of disease has not been definitively demonstrated. Confounding factors, such as compliance, soap volume, and wash time, may all influence the outcomes of studies. The aim of this work was to examine the effects of wash time and soap volume on the relative activities and the subsequent transfer of bacteria to inanimate objects for antimicrobial and nonantimicrobial soaps. Increasing the wash time from 15 to 30 seconds increased reduction of Shigella flexneri from 2.90 to 3.33 log(10) counts (P = 0.086) for the antimicrobial soap, while nonantimicrobial soap achieved reductions of 1.72 and 1.67 log(10) counts (P > 0.6). Increasing soap volume increased bacterial reductions for both the antimicrobial and the nonantimicrobial soaps. When the soap volume was normalized based on weight (approximately 3 g), nonantimicrobial soap reduced Serratia marcescens by 1.08 log(10) counts, compared to the 3.83-log(10) reduction caused by the antimicrobial soap (P < 0.001). The transfer of Escherichia coli to plastic balls following a 15-second hand wash with antimicrobial soap resulted in a bacterial recovery of 2.49 log(10) counts, compared to the 4.22-log(10) (P < 0.001) bacterial recovery on balls handled by hands washed with nonantimicrobial soap. This indicates that nonantimicrobial soap was less active and that the effectiveness of antimicrobial soaps can be improved with longer wash time and greater soap volume. The transfer of bacteria to objects was significantly reduced due to greater reduction in bacteria following the use of antimicrobial soap.

Evaluation of various agro-wastes for traditional black soap production.

PubMed

Taiwo, O E; Osinowo, F A

2001-08-01

The agricultural wastes, cocoa-pod husks, palm-bunch waste, sorghum chaff and groundnut shells, which are normally thrown away have been used in the production of black soap. Unlike other soaps which are made from oils and chemicals, black soap is made from oils and agro-wastes ashes. Chemical analysis indicated that the liquid extract from the ashes of the different agro-wastes used contained various amounts of potassium and sodium compounds. The most common ingredient in the agro-wastes was potassium carbonate. The amount of potassium carbonate was 56.73 +/- 0.16% in cocoa-pod ash, 43.15 +/- 0.13% in palm-bunch ash, 16.65 +/- 0.05% in groundnut shell ash and 12.40 +/- 0.08% in sorghum chaff ash. Soaps made from the agro-wastes ashes had excellent solubility, consistency, cleansing and lathering abilities.

Exploring Determinants of Handwashing with Soap in Indonesia: A Quantitative Analysis

PubMed Central

Hirai, Mitsuaki; Graham, Jay P.; Mattson, Kay D.; Kelsey, Andrea; Mukherji, Supriya; Cronin, Aidan A.

2016-01-01

Handwashing with soap is recognized as a cost-effective intervention to reduce morbidity and mortality associated with enteric and respiratory infections. This study analyzes rural Indonesian households’ hygiene behaviors and attitudes to examine how motivations for handwashing, locations of handwashing space in the household, and handwashing moments are associated with handwashing with soap as potential determinants of the behavior. The analysis was conducted using results from a UNICEF cross-sectional study of 1700 households in six districts across three provinces of Indonesia. A composite measure of handwashing with soap was developed that included self-reported handwashing, a handwashing demonstration, and observed handwashing materials and location of facilities in the home. Prevalence ratios were calculated to analyze associations between handwashing with soap and hypothesized determinants of the behavior. Our results showed that determinants that had a significant association with handwashing with soap included: (1) a desire to smell nice; (2) interpersonal influences; (3) the presence of handwashing places within 10 paces of the kitchen and the toilet; and (4) key handwashing moments when hands felt dirty, including after eating and after cleaning child stools. This study concludes that handwashing with soap may be more effectively promoted through the use of non-health messages. PMID:27598178

Exploring Determinants of Handwashing with Soap in Indonesia: A Quantitative Analysis.

PubMed

Hirai, Mitsuaki; Graham, Jay P; Mattson, Kay D; Kelsey, Andrea; Mukherji, Supriya; Cronin, Aidan A

2016-09-01

Handwashing with soap is recognized as a cost-effective intervention to reduce morbidity and mortality associated with enteric and respiratory infections. This study analyzes rural Indonesian households' hygiene behaviors and attitudes to examine how motivations for handwashing, locations of handwashing space in the household, and handwashing moments are associated with handwashing with soap as potential determinants of the behavior. The analysis was conducted using results from a UNICEF cross-sectional study of 1700 households in six districts across three provinces of Indonesia. A composite measure of handwashing with soap was developed that included self-reported handwashing, a handwashing demonstration, and observed handwashing materials and location of facilities in the home. Prevalence ratios were calculated to analyze associations between handwashing with soap and hypothesized determinants of the behavior. Our results showed that determinants that had a significant association with handwashing with soap included: (1) a desire to smell nice; (2) interpersonal influences; (3) the presence of handwashing places within 10 paces of the kitchen and the toilet; and (4) key handwashing moments when hands felt dirty, including after eating and after cleaning child stools. This study concludes that handwashing with soap may be more effectively promoted through the use of non-health messages.

A High Performance SOAP Engine for Grid Computing

NASA Astrophysics Data System (ADS)

Wang, Ning; Welzl, Michael; Zhang, Liang

Web Service technology still has many defects that make its usage for Grid computing problematic, most notably the low performance of the SOAP engine. In this paper, we develop a novel SOAP engine called SOAPExpress, which adopts two key techniques for improving processing performance: SCTP data transport and dynamic early binding based data mapping. Experimental results show a significant and consistent performance improvement of SOAPExpress over Apache Axis.

Mother Courage and Her Soaps: "Incendies, Weeds, Nurse Jackie," and Daytime Drama

ERIC Educational Resources Information Center

Beck, Bernard

2012-01-01

The decline of the soap opera as a major form of popular culture highlights the importance of that form in creating and maintaining a shared subculture for women. Soap operas are contrasted with recent television and film works that present the struggles of women in a different way, highlighting the distinctive features of soap operas as women's…

40 CFR 417.80 - Applicability; description of the manufacture of liquid soaps subcategory.

Code of Federal Regulations, 2014 CFR

2014-07-01

... manufacture of liquid soaps subcategory. 417.80 Section 417.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Liquid Soaps Subcategory § 417.80 Applicability; description of the manufacture of...

40 CFR 417.80 - Applicability; description of the manufacture of liquid soaps subcategory.

Code of Federal Regulations, 2013 CFR

2013-07-01

... manufacture of liquid soaps subcategory. 417.80 Section 417.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Liquid Soaps Subcategory § 417.80 Applicability; description of the manufacture of...

40 CFR 417.70 - Applicability; description of the manufacture of bar soaps subcategory.

Code of Federal Regulations, 2013 CFR

2013-07-01

... manufacture of bar soaps subcategory. 417.70 Section 417.70 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Bar Soaps Subcategory § 417.70 Applicability; description of the manufacture of bar...

40 CFR 417.80 - Applicability; description of the manufacture of liquid soaps subcategory.

Code of Federal Regulations, 2012 CFR

2012-07-01

... manufacture of liquid soaps subcategory. 417.80 Section 417.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Liquid Soaps Subcategory § 417.80 Applicability; description of the manufacture of...

40 CFR 417.70 - Applicability; description of the manufacture of bar soaps subcategory.

Code of Federal Regulations, 2012 CFR

2012-07-01

... manufacture of bar soaps subcategory. 417.70 Section 417.70 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Bar Soaps Subcategory § 417.70 Applicability; description of the manufacture of bar...

40 CFR 417.70 - Applicability; description of the manufacture of bar soaps subcategory.

Code of Federal Regulations, 2014 CFR

2014-07-01

... manufacture of bar soaps subcategory. 417.70 Section 417.70 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Bar Soaps Subcategory § 417.70 Applicability; description of the manufacture of bar...

The 'Dope' on Soaps.

ERIC Educational Resources Information Center

MacDonald, Patrick T.

1983-01-01

Used a sample of 165 long-time soap opera viewers to examine the context, motives, and consequences of drug use in daytime serials. Results showed alcohol was seen more frequently than any other drug. Portrayal of illegal drugs was much less common than that of legal drugs. (JAC)

SPICE Module for the Satellite Orbit Analysis Program (SOAP)

NASA Technical Reports Server (NTRS)

Coggi, John; Carnright, Robert; Hildebrand, Claude

2008-01-01

A SPICE module for the Satellite Orbit Analysis Program (SOAP) precisely represents complex motion and maneuvers in an interactive, 3D animated environment with support for user-defined quantitative outputs. (SPICE stands for Spacecraft, Planet, Instrument, Camera-matrix, and Events). This module enables the SOAP software to exploit NASA mission ephemeris represented in the JPL Ancillary Information Facility (NAIF) SPICE formats. Ephemeris types supported include position, velocity, and orientation for spacecraft and planetary bodies including the Sun, planets, natural satellites, comets, and asteroids. Entire missions can now be imported into SOAP for 3D visualization, playback, and analysis. The SOAP analysis and display features can now leverage detailed mission files to offer the analyst both a numerically correct and aesthetically pleasing combination of results that can be varied to study many hypothetical scenarios. The software provides a modeling and simulation environment that can encompass a broad variety of problems using orbital prediction. For example, ground coverage analysis, communications analysis, power and thermal analysis, and 3D visualization that provide the user with insight into complex geometric relations are included. The SOAP SPICE module allows distributed science and engineering teams to share common mission models of known pedigree, which greatly reduces duplication of effort and the potential for error. The use of the software spans all phases of the space system lifecycle, from the study of future concepts to operations and anomaly analysis. It allows SOAP software to correctly position and orient all of the principal bodies of the Solar System within a single simulation session along with multiple spacecraft trajectories and the orientation of mission payloads. In addition to the 3D visualization, the user can define numeric variables and x-y plots to quantitatively assess metrics of interest.

Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers.

PubMed

Zawko, Scott A; Schmidt, Christine E

2011-08-01

An objective of tissue engineering is to create synthetic polymer scaffolds with a fibrillar microstructure similar to the extracellular matrix. Here, we present a novel method for creating polymer fibers using the layer-by-layer method and sacrificial templates composed of sodium soap fibers. Soap fibers were prepared from neutralized fatty acids using a sodium chloride crystal dissolution method. Polyelectrolyte multilayers (PEMs) of polystyrene sulfonate and polyallylamine hydrochloride were deposited onto the soap fibers, crosslinked with glutaraldehyde, and then the soap fibers were leached with warm water and ethanol. The morphology of the resulting PEM structures was a dense network of fibers surrounded by a nonfibrillar matrix. Microscopy revealed that the PEM fibers were solid structures, presumably composed of polyelectrolytes complexed with residual fatty acids. These fibrillar PEM films were found to support the attachment of human dermal fibroblasts. Copyright © 2011 Wiley Periodicals, Inc.

A community-randomised controlled trial promoting waterless hand sanitizer and handwashing with soap, Dhaka, Bangladesh.

PubMed

Luby, Stephen P; Kadir, Mohammad Abdul; Yushuf Sharker, M A; Yeasmin, Farzana; Unicomb, Leanne; Sirajul Islam, M

2010-12-01

To pilot two intensive hand hygiene promotion interventions, one using soap and one using a waterless hand sanitizer, in low-income housing compounds in Dhaka, Bangladesh and assess subsequent changes in handwashing behaviour and hand microbiology. Fieldworkers randomized 30 housing compounds: 10 received handwashing promotion with free soap, 10 received handwashing promotion with free waterless hand sanitizer and 10 were non-intervention controls. Fieldworkers assessed handwashing behaviour by structured observation and collected hand rinse specimens. At baseline, compound residents washed their hands with soap 26% of the time after defecation and 30% after cleaning a child's anus but <1% at other times. Compared with baseline, residents of soap intervention compounds were much more likely to wash their hands with soap after faecal contact (85-91%), before preparing food (26%) and before eating (26%). Compounds that received waterless hand sanitizer cleansed their hands more commonly than control compounds that used soap (10.4%vs. 2.3%), but less commonly than soap intervention compounds used soap (25%). Post-intervention hand rinse samples from soap and sanitizer compounds had lower concentrations of faecal indicator bacteria compared with baseline and control compounds. Waterless hand sanitizer was readily adopted by this low-income community and reduced hand contamination but did not improve the frequency of handwashing compared with soap. Future deployments of waterless hand sanitizers may improve hand hygiene more effectively by targeting settings where soap and water is unavailable. © 2010 Blackwell Publishing Ltd.

Green Soap: An Extraction and Saponification of Avocado Oil

ERIC Educational Resources Information Center

Sutheimer, Susan; Caster, Jacqueline M.; Smith, Simone H.

2015-01-01

An introductory level green chemistry experiment is described that places a new twist on soap-making in lab. In this experiment, oil is extracted from an avocado, after which the oil is saponified to produce bars of green craft soap. Commonly used extraction solvents, such as petroleum ether, methylene chloride, and hexane, are replaced with safer…

Observation procedure, observer gender, and behavior valence as determinants of sampling error in a behavior assessment analogue

PubMed Central

Farkas, Gary M.; Tharp, Roland G.

1980-01-01

Several factors thought to influence the representativeness of behavioral assessment data were examined in an analogue study using a multifactorial design. Systematic and unsystematic methods of observing group behavior were investigated using 18 male and 18 female observers. Additionally, valence properties of the observed behaviors were inspected. Observers' assessments of a videotape were compared to a criterion code that defined the population of behaviors. Results indicated that systematic observation procedures were more accurate than unsystematic procedures, though this factor interacted with gender of observer and valence of behavior. Additionally, males tended to sample more representatively than females. A third finding indicated that the negatively valenced behavior was overestimated, whereas the neutral and positively valenced behaviors were accurately assessed. PMID:16795631

NPDES Permit for Soap Creek Associates Wastewater Treatment Facility in Montana

EPA Pesticide Factsheets

Under National Pollutant Discharge Elimination System permit number MT-0023183, Soap Creek Associates, Inc. is authorized to discharge from its wastewater treatment facility located in West, Bighorn County, Montana, to Soap Creek.

40 CFR 417.70 - Applicability; description of the manufacture of bar soaps subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 29 2011-07-01 2009-07-01 true Applicability; description of the manufacture of bar soaps subcategory. 417.70 Section 417.70 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Bar Soaps Subcategor...

40 CFR 417.70 - Applicability; description of the manufacture of bar soaps subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Applicability; description of the manufacture of bar soaps subcategory. 417.70 Section 417.70 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Bar Soaps Subcategor...

40 CFR 417.80 - Applicability; description of the manufacture of liquid soaps subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 29 2011-07-01 2009-07-01 true Applicability; description of the manufacture of liquid soaps subcategory. 417.80 Section 417.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Liquid Soaps...

40 CFR 417.80 - Applicability; description of the manufacture of liquid soaps subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Applicability; description of the manufacture of liquid soaps subcategory. 417.80 Section 417.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Liquid Soaps...

The crystallization of metal soaps and fatty acids in oil paint model systems.

PubMed

Hermans, Joen J; Keune, Katrien; van Loon, Annelies; Iedema, Piet D

2016-04-28

The formation and crystallization of metal soaps in oil paint layers is an important issue in the conservation of oil paintings. The chemical reactions and physical processes that are involved in releasing metal ions from pigments and fatty acids from the oil binder to form crystalline metal soap deposits have so far remained poorly understood. We have used a combination of differential scanning calorimetry (DSC) and attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) on model mixtures of palmitic acid, lead palmitate or zinc palmitate and linseed oil to study the transition from amorphous material to crystalline fatty acid or metal soap. This transition forms the final stage in the cascade of processes leading to metal soap-related oil paint degradation. Palmitic acid as well as the metal soaps showed nearly ideal solubility behavior. However, it was found that, near room temperature, both lead and zinc palmitate are practically insoluble in both liquid and partially polymerized linseed oil. Interestingly, the rate of metal soap and fatty acid crystallization decreased rapidly with the degree of linseed oil polymerization, possibly leading to systems where metal soaps are kinetically trapped in a semi-crystalline state. To explain the various morphologies of metal soap aggregates observed in oil paint layers, it is proposed that factors affecting the probability of crystal nucleation and the rate of crystal growth play a crucial role, like exposure to heat or cleaning solvents and the presence of microcracks.

Larvicidal activity of synthetic disinfectants and antibacterial soaps against mosquito, Culex quinquefasciatus (Diptera: Culicidae).

PubMed

Xue, Rui-De; Qualls, Whitney A

2013-01-01

Seven commercial synthetic disinfectant and antibacterial soap products were evaluated as mosquito larvicides against Culex quinquefasciatus Say in the laboratory. Three aerosol disinfectant products, at 0.01% concentration resulted in 58-76% mortality of laboratory-reared fourth instar mosquito larvae at 24 h posttreatment. Four antibacterial soap products at 0.0001% concentration resulted in 88-100% larval mortality at 24 h posttreatment. The active ingredient of the antibacterial soap products, triclosan (0.1%) resulted in 74% larval mortality. One of the antibacterial soap products, Equate caused the highest mosquito larval mortality in the laboratory. Equate antibacterial soap at the application rate of 0.000053 ppm resulted in 90% mortality of the introduced fourth instar larvae of Cx. quinquesfasicatus in the outdoor pools. In laboratory and field bioassays, the antibacterial soap resulted in significant larval mosquito mortality.

6. FOURTH FLOOR, DETAIL OF HOTEL SOAP LINE TO NORTH: ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. FOURTH FLOOR, DETAIL OF HOTEL SOAP LINE TO NORTH: AMERICAN CAR & FOUNDRY COMPANY MANUAL SOAP CUTTER INSTALLED 1932 (FOREGROUND); CONVEYORS; AND R.A. JONES & COMPANY HORIZONTAL PRESS INSTALLED 1931 (BACKGROUND) - Colgate & Company Jersey City Plant, Building No. B-15, 90-96 Greene Street, Jersey City, Hudson County, NJ

Quantifying the Effects of Water Temperature, Soap Volume, Lather Time, and Antimicrobial Soap as Variables in the Removal of Escherichia coli ATCC 11229 from Hands.

PubMed

Jensen, Dane A; Macinga, David R; Shumaker, David J; Bellino, Roberto; Arbogast, James W; Schaffner, Donald W

2017-06-01

The literature on hand washing, while extensive, often contains conflicting data, and key variables are only superficially studied or not studied at all. Some hand washing recommendations are made without scientific support, and agreement between recommendations is limited. The influence of key variables such as soap volume, lather time, water temperature, and product formulation on hand washing efficacy was investigated in the present study. Baseline conditions were 1 mL of a bland (nonantimicrobial) soap, a 5-s lather time, and 38°C (100°F) water temperature. A nonpathogenic strain of Escherichia coli (ATCC 11229) was the challenge microorganism. Twenty volunteers (10 men and 10 women) participated in the study, and each test condition had 20 replicates. An antimicrobial soap formulation (1% chloroxylenol) was not significantly more effective than the bland soap for removing E. coli under a variety of test conditions. Overall, the mean reduction was 1.94 log CFU (range, 1.83 to 2.10 log CFU) with the antimicrobial soap and 2.22 log CFU (range, 1.91 to 2.54 log CFU) with the bland soap. Overall, lather time significantly influenced efficacy in one scenario, in which a 0.5-log greater reduction was observed after 20 s with bland soap compared with the baseline wash (P = 0.020). Water temperature as high as 38°C (100°F) and as low as 15°C (60°F) did not have a significant effect on the reduction of bacteria during hand washing; however, the energy usage differed between these temperatures. No significant differences were observed in mean log reductions experienced by men and women (both 2.08 log CFU; P = 0.988). A large part of the variability in the data was associated with the behaviors of the volunteers. Understanding what behaviors and human factors most influence hand washing may help researchers find techniques to optimize the effectiveness of hand washing.

Digitization Procedures of Analogue Seismograms from the Adam Dziewonski Observatory (HRV) at Harvard, MA

NASA Astrophysics Data System (ADS)

Torpey, M.; Ishii, M.

2010-12-01

This project explores methods of digitization of analogue seismic recordings for better preservation and to facilitate data distribution to the community. Different techniques are investigated using seismograms from one particular station, the Adam Dziewonski Observatory (HRV) at Harvard, Massachusetts. This seismological station, still in operation as a part of the Global Seismographic Network today, is one of the oldest stations in the United States. The station was built in 1933, and since its installation, the station has produced approximately 16,000 analogue seismograms. The majority of these recordings were taken between 1933 and 1953, with some intermittent recordings between 1962 and 1998 after digital seismometers had become a standard. These analogue seismograms have the potential of expanding the database for seismological research such as identification of events previously not catalogued. Due to poor storage environment at the station, some of the records, especially those on regular type of paper, are damaged beyond repair. Nevertheless, many of the records on photographic paper are in better condition, and we have focused on a subset of these recordings that are least damaged. Even these seismograms require cleaning and, in consultation with the Weissman Preservation Center of Harvard Library, preparation techniques for the photographic records are examined. After the seismograms are cleaned and flattened, three different equipments are investigated for digitization, i.e., a copy machine, scanner, and camera. These instruments allow different imaging resolutions, ranging from 200 dots per inch (dpi) to 800 dpi. The image resolution and the bit depth have a wide range of implications that are closely linked to the digitization program one chooses to convert the image to time series. We explore three different software for this conversion, SeisDig (Bromirski and Chuang, 2003), Teseo2 (Pintore and Quintiliani, 2008), and NeuraLog (www

Use Primary Sources to Develop a Soap Opera: As the Civil War Turns

ERIC Educational Resources Information Center

Morris, Ronald V.

2002-01-01

In this article, the author describes a social studies class activity that uses primary sources to develop a soap opera based on the American Civil War. In the soap opera activity, students can watch historical characters as they grow, develop, and change. Not only do people in the soap opera develop over a long period, but their accumulated…

Memory effects in soap film arrangements

NASA Astrophysics Data System (ADS)

Vandewalle, Nicolas; Dorbolo, Stephane; Lumay, Geoffroy; Schockmel, Julien; Noirhomme, Martial

2012-02-01

We report experiments on soap film configurations in a triangular prism for which the shape factor can be changed continuously. Two stable configurations can be observed for a range of the shape factor h. A hysteretic behaviour is found, due to the occurence of another local minima in the free energy. Experiments demonstrate that soap films can be trapped in a particular configuration being different from a global surface minimization. This metastability can be evidenced from a geometrical model based on idealized structures. Depending on the configuration, providing clues on the structural relaxations taking place into 3D foams, such as T1 rearrangements. The composition of the liquid is also investigated leading to dynamical picture of the transition. (Phys. Rev. E 83, 021403 (2011))

Jet impact on a soap film

NASA Astrophysics Data System (ADS)

Kirstetter, Geoffroy; Raufaste, Christophe; Celestini, Franck

2012-09-01

We experimentally investigate the impact of a liquid jet on a soap film. We observe that the jet never breaks the film and that two qualitatively different steady regimes may occur. The first one is a refractionlike behavior obtained at small incidence angles when the jet crosses the film and is deflected by the film-jet interaction. For larger incidence angles, the jet is absorbed by the film, giving rise to a new class of flows in which the jet undulates along the film with a characteristic wavelength. Besides its fundamental interest, this paper presents a different way to guide a micrometric flow of liquid in the inertial regime and to probe foam stability submitted to violent perturbations at the soap film scale.

Jet impact on a soap film.

PubMed

Kirstetter, Geoffroy; Raufaste, Christophe; Celestini, Franck

2012-09-01

We experimentally investigate the impact of a liquid jet on a soap film. We observe that the jet never breaks the film and that two qualitatively different steady regimes may occur. The first one is a refractionlike behavior obtained at small incidence angles when the jet crosses the film and is deflected by the film-jet interaction. For larger incidence angles, the jet is absorbed by the film, giving rise to a new class of flows in which the jet undulates along the film with a characteristic wavelength. Besides its fundamental interest, this paper presents a different way to guide a micrometric flow of liquid in the inertial regime and to probe foam stability submitted to violent perturbations at the soap film scale.

40 CFR 467.60 - Applicability; description of the drawing with emulsions or soaps subcategory.

Code of Federal Regulations, 2013 CFR

2013-07-01

... drawing with emulsions or soaps subcategory. 467.60 Section 467.60 Protection of Environment ENVIRONMENTAL... CATEGORY Drawing With Emulsions or Soaps Subcategory § 467.60 Applicability; description of the drawing with emulsions or soaps subcategory. This subpart applies to discharges of pollutants to waters of the...

40 CFR 467.60 - Applicability; description of the drawing with emulsions or soaps subcategory.

Code of Federal Regulations, 2014 CFR

2014-07-01

... drawing with emulsions or soaps subcategory. 467.60 Section 467.60 Protection of Environment ENVIRONMENTAL... CATEGORY Drawing With Emulsions or Soaps Subcategory § 467.60 Applicability; description of the drawing with emulsions or soaps subcategory. This subpart applies to discharges of pollutants to waters of the...

40 CFR 467.60 - Applicability; description of the drawing with emulsions or soaps subcategory.

Code of Federal Regulations, 2012 CFR

2012-07-01

... drawing with emulsions or soaps subcategory. 467.60 Section 467.60 Protection of Environment ENVIRONMENTAL... CATEGORY Drawing With Emulsions or Soaps Subcategory § 467.60 Applicability; description of the drawing with emulsions or soaps subcategory. This subpart applies to discharges of pollutants to waters of the...

Is cutaneous malignant melanoma associated with the use of antibacterial soaps?

PubMed

Arbesman, H

1999-07-01

Since 1960, the incidence of melanoma has increased dramatically in Caucasians worldwide, and during the past decade has risen at a rate of 6% a year in the USA. A hypothesis regarding this increased incidence suggests that the prevalent use of antibacterial soaps that contain photosensitizing compounds may be a risk factor for the development of cutaneous malignant melanoma. These antibacterial soaps were introduced in the 1960s and compounds with photosensitizing properties are still present in various soaps throughout the industrialized world. The use of these antibacterial soaps, in combination with sun exposure, leads to free radical production in the skin. These free radicals are hypothesized to cause damage to melanocytes, leading to the development of melanoma. Various epidemiological findings regarding melanoma are consistent with this hypothesis. A significant reduction in the number of new cases of melanoma could be achieved if this hypothesis is correct.

40 CFR 417.10 - Applicability; description of the soap manufacturing by batch kettle subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Applicability; description of the soap manufacturing by batch kettle subcategory. 417.10 Section 417.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by...

40 CFR 417.10 - Applicability; description of the soap manufacturing by batch kettle subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 29 2011-07-01 2009-07-01 true Applicability; description of the soap manufacturing by batch kettle subcategory. 417.10 Section 417.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by...

Mobile Cloud Computing with SOAP and REST Web Services

NASA Astrophysics Data System (ADS)

Ali, Mushtaq; Fadli Zolkipli, Mohamad; Mohamad Zain, Jasni; Anwar, Shahid

2018-05-01

Mobile computing in conjunction with Mobile web services drives a strong approach where the limitations of mobile devices may possibly be tackled. Mobile Web Services are based on two types of technologies; SOAP and REST, which works with the existing protocols to develop Web services. Both the approaches carry their own distinct features, yet to keep the constraint features of mobile devices in mind, the better in two is considered to be the one which minimize the computation and transmission overhead while offloading. The load transferring of mobile device to remote servers for execution called computational offloading. There are numerous approaches to implement computational offloading a viable solution for eradicating the resources constraints of mobile device, yet a dynamic method of computational offloading is always required for a smooth and simple migration of complex tasks. The intention of this work is to present a distinctive approach which may not engage the mobile resources for longer time. The concept of web services utilized in our work to delegate the computational intensive tasks for remote execution. We tested both SOAP Web services approach and REST Web Services for mobile computing. Two parameters considered in our lab experiments to test; Execution Time and Energy Consumption. The results show that RESTful Web services execution is far better than executing the same application by SOAP Web services approach, in terms of execution time and energy consumption. Conducting experiments with the developed prototype matrix multiplication app, REST execution time is about 200% better than SOAP execution approach. In case of energy consumption REST execution is about 250% better than SOAP execution approach.

Evaluation of pH of Bathing Soaps and Shampoos for Skin and Hair Care.

PubMed

Tarun, Jose; Susan, Jose; Suria, Jacob; Susan, Veronica John; Criton, Sebastian

2014-09-01

Normal healthy skin has potential of hydrogen (pH) range of 5.4-5.9 and a normal bacterial flora. Use of soap with high pH causes an increase in skin pH, which in turn causes an increase in dehydrative effect, irritability and alteration in bacterial flora. The majority of soaps and shampoos available in the market do not disclose their pH. The aim of this study was to assess the pH of different brands of bathing soaps and shampoos available in the market. The samples of soaps and shampoos were collected from shops in the locality. The samples of different brands are coded before the analysis of the pH. Solution of each sample was made and pH was measured using pH meter. Majority of the soaps have a pH within the range of 9-10. Majority of the shampoos have a pH within the range of 6-7. The soaps and shampoos commonly used by the population at large have a pH outside the range of normal skin and hair pH values. Therefore, it is hoped that before recommending soap to patient especially those who have sensitive and acne prone skin, due consideration is given to the pH factor and also that manufacturers will give a thought to pH of soaps and shampoos manufactured by them, so that their products will be more skin and hair friendly.

Simultaneous determination of three surfactants and water in shampoo and liquid soap by ATR-FTIR.

PubMed

Carolei, Luciano; Gutz, Ivano G R

2005-03-31

It is demonstrated for the first time that the principal constituents of a shampoo as well as of a liquid soap -three surfactants and water- can be determined directly, simultaneously and quickly in undiluted samples by attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy in the middle infrared region, despite the broad absorption bands of the solvent. Two of the surfactants, sodium lauryl ether sulfate (SLES) and cocoamidopropyl betaine (CAPB), are common to both formulations; alkylpolyglucoside (APG) is the third surfactant of the liquid soap and cocodiethanolamide (CDEA), the corresponding ingredient of the shampoo. Absorbance data of the undiluted samples and of the calibration standards was collected in the middle infrared region of the spectrum (800-1600 and 1900-3000cm(-1)). Two methods of multivariate quantification were compared: classical least squares (CLS), where absorbance data measured at 200 wavenumbers was processed, and inverse least squares (ILS), where data at 10 selected wavenumbers was analyzed. A spectra normalization procedure, based on a dominating water band, was examined. Twenty-seven standard mixtures were used for each application, consisting of all combinations at three concentration levels of each surfactant, respectively the lower limit, the expected value and the upper limit accepted in quality control. By favoring wavenumbers where absorption bands of the minor components (APG in the liquid soap and CDEA in the shampoo) are more intense, good results were obtained for 18 simulated samples of shampoo and 18 samples of liquid soap, no matter if calculations were made by CLS or ILS. The relative errors for water (major component, 84-88%) and SLES (7-10%) were always below 2%; for CAPB (2-4%), APG (<2%) and CDEA (<2%), they occasionally reached 5% of the component, an uncertainty of less than 0.07% in terms of the sample weight.

Electron Microscopy Imaging of Zinc Soaps Nucleation in Oil Paint.

PubMed

Hermans, Joen; Osmond, Gillian; van Loon, Annelies; Iedema, Piet; Chapman, Robyn; Drennan, John; Jack, Kevin; Rasch, Ronald; Morgan, Garry; Zhang, Zhi; Monteiro, Michael; Keune, Katrien

2018-06-04

Using the recently developed techniques of electron tomography, we have explored the first stages of disfiguring formation of zinc soaps in modern oil paintings. The formation of complexes of zinc ions with fatty acids in paint layers is a major threat to the stability and appearance of many late 19th and early 20th century oil paintings. Moreover, the occurrence of zinc soaps in oil paintings leading to defects is disturbingly common, but the chemical reactions and migration mechanisms leading to large zinc soap aggregates or zones remain poorly understood. State-of-the-art scanning (SEM) and transmission (TEM) electron microscopy techniques, primarily developed for biological specimens, have enabled us to visualize the earliest stages of crystalline zinc soap growth in a reconstructed zinc white (ZnO) oil paint sample. In situ sectioning techniques and sequential imaging within the SEM allowed three-dimensional tomographic reconstruction of sample morphology. Improvements in the detection and discrimination of backscattered electrons enabled us to identify local precipitation processes with small atomic number contrast. The SEM images were correlated to low-dose and high-sensitivity TEM images, with high-resolution tomography providing unprecedented insight into the structure of nucleating zinc soaps at the molecular level. The correlative approach applied here to study phase separation, and crystallization processes specific to a problem in art conservation creates possibilities for visualization of phase formation in a wide range of soft materials.

Laundry Soap from Waste Cooking Oil. What We Make. Science and Technology Education in Philippine Society.

ERIC Educational Resources Information Center

Philippines Univ., Quezon City. Inst. for Science and Mathematics Education Development.

This module provides instructions for clarifying cooking oil and using it with either wood ash lye or commercial lye to make laundry soap. It also provides (in appendices): a discussion of oils and soaps, including the history of soap; instructions for preparing an 18 percent lye solution; instructions for preparing soap using lye from wood ash;…

40 CFR 417.60 - Applicability; description of the manufacture of soap flakes and powders subcategory.

Code of Federal Regulations, 2014 CFR

2014-07-01

... manufacture of soap flakes and powders subcategory. 417.60 Section 417.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Soap Flakes and Powders Subcategory § 417.60 Applicability...

40 CFR 417.60 - Applicability; description of the manufacture of soap flakes and powders subcategory.

Code of Federal Regulations, 2012 CFR

2012-07-01

... manufacture of soap flakes and powders subcategory. 417.60 Section 417.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Soap Flakes and Powders Subcategory § 417.60 Applicability...

40 CFR 417.60 - Applicability; description of the manufacture of soap flakes and powders subcategory.

Code of Federal Regulations, 2013 CFR

2013-07-01

... manufacture of soap flakes and powders subcategory. 417.60 Section 417.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Soap Flakes and Powders Subcategory § 417.60 Applicability...

40 CFR 417.30 - Applicability; description of the soap manufacturing by fatty acid neutralization subcategory.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 30 2012-07-01 2012-07-01 false Applicability; description of the soap... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by Fatty Acid Neutralization Subcategory § 417.30 Applicability...

40 CFR 417.30 - Applicability; description of the soap manufacturing by fatty acid neutralization subcategory.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 30 2013-07-01 2012-07-01 true Applicability; description of the soap... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by Fatty Acid Neutralization Subcategory § 417.30 Applicability...

40 CFR 417.30 - Applicability; description of the soap manufacturing by fatty acid neutralization subcategory.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 29 2014-07-01 2012-07-01 true Applicability; description of the soap... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by Fatty Acid Neutralization Subcategory § 417.30 Applicability...

Quasi-steady vortical structures in vertically vibrating soap films

NASA Astrophysics Data System (ADS)

Vega, José M.; Higuera, F. J.; Weidman, P. D.

1998-10-01

An analysis of the quasi-steady streaming of the liquid in a vertically vibrated horizontal soap film is reported. The air around the soap film is seen to play a variety of roles: it transmits normal and tangential oscillatory stresses to the film, damps out Marangoni waves, and forces non-oscillatory deflection of the film and tangential motion of the liquid. Non-oscillatory volume forcing originating inside the liquid is also analysed. This forcing dominates the quasi-steady streaming when the excitation frequency is close to the eigenfrequency of a Marangoni mode of the soap film, while both volume forcing in the liquid and surface forcing of the gas on the liquid are important when no Marangoni mode resonates. Different manners by which the combined forcings can induce quasi-steady streaming motion are discussed and some numerical simulations of the quasi-steady liquid flow are presented.

40 CFR 417.30 - Applicability; description of the soap manufacturing by fatty acid neutralization subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 29 2011-07-01 2009-07-01 true Applicability; description of the soap manufacturing by fatty acid neutralization subcategory. 417.30 Section 417.30 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap...

Child toy safety: An interdisciplinary approach to unravel the microbiological hazard posed by soap bubbles.

PubMed

Amoruso, Irene; Bertoncello, Chiara; Caravello, Gianumberto; Giaccone, Valerio; Baldovin, Tatjana

2015-11-01

In 2012 some children developed sepsis after playing together with a soap bubble toy. Microbiological testing revealed heavy contamination of the soap solution, which reasonably represented the vehicle of infection. We investigated the issue with a multidisciplinary approach: review of toy safety legislation; microbiological testing of additional samples; query of the RAPEX database for non-compliant soap bubbles; identification of major manufacturing districts. Microbiological contamination of industrial soap bubbles was widespread. Sixty-three notifications of batches contaminated by environmental microorganisms and opportunistic pathogens had been reported. The Chinese had a virtual monopoly of the soap bubble market. We identified two main manufacturing districts in Guangdong Province, both notable for degradation of their water resources. The use of untreated water for the industrial production of soap bubbles may explain the bacterial contamination. Existing legislation provides an unsatisfactory approach for managing microbiological hazards in sensitive toy categories and for identifying responsible parties in import and export of the products.

Human health risk assessment of chloroxylenol in liquid hand soap and dishwashing soap used by consumers and health-care professionals.

PubMed

Yost, Lisa J; Rodricks, Joseph D; Turnbull, Duncan; DeLeo, Paul C; Nash, J Frank; Quiñones-Rivera, Antonio; Carlson, Pete A

2016-10-01

A quantitative human risk assessment of chloroxylenol was conducted for liquid hand and dishwashing soap products used by consumers and health-care workers. The toxicological data for chloroxylenol indicate lack of genotoxicity, no evidence of carcinogenicity, and minimal systemic toxicity. No observed adverse effect levels (NOAEL) were established from chronic toxicity studies, specifically a carcinogenicity study that found no cancer excess (18 mg/kg-day) and studies of developmental and reproductive toxicity (100 mg/kg-day). Exposure to chloroxylenol for adults and children was estimated for two types of rinse-off cleaning products, one liquid hand soap, and two dishwashing products. The identified NOAELs were used together with exposure estimates to derive margin of exposure (MOE) estimates for chloroxylenol (i.e., estimates of exposure over NOAELs). These estimates were designed with conservative assumptions and likely overestimate exposure and risk (i.e., highest frequency, 100% dermal penetration). The resulting MOEs ranged from 178 to over 100, 000, 000 indicating negligibly small potential for harm related to consumer or health-care worker exposure to chloroxylenol in liquid soaps used in dish washing and hand washing. Copyright © 2016 Elsevier Inc. All rights reserved.

40 CFR 417.60 - Applicability; description of the manufacture of soap flakes and powders subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 29 2011-07-01 2009-07-01 true Applicability; description of the manufacture of soap flakes and powders subcategory. 417.60 Section 417.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Soap...

40 CFR 417.60 - Applicability; description of the manufacture of soap flakes and powders subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Applicability; description of the manufacture of soap flakes and powders subcategory. 417.60 Section 417.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Soap...

TCP/IP Interface for the Satellite Orbit Analysis Program (SOAP)

NASA Technical Reports Server (NTRS)

Carnright, Robert; Stodden, David; Coggi, John

2009-01-01

The Transmission Control Protocol/ Internet protocol (TCP/IP) interface for the Satellite Orbit Analysis Program (SOAP) provides the means for the software to establish real-time interfaces with other software. Such interfaces can operate between two programs, either on the same computer or on different computers joined by a network. The SOAP TCP/IP module employs a client/server interface where SOAP is the server and other applications can be clients. Real-time interfaces between software offer a number of advantages over embedding all of the common functionality within a single program. One advantage is that they allow each program to divide the computation labor between processors or computers running the separate applications. Secondly, each program can be allowed to provide its own expertise domain with other programs able to use this expertise.

Soap is not enough: handwashing practices and knowledge in refugee camps, Maban County, South Sudan.

PubMed

Phillips, Raina M; Vujcic, Jelena; Boscoe, Andrew; Handzel, Thomas; Aninyasi, Mark; Cookson, Susan T; Blanton, Curtis; S Blum, Lauren; Ram, Pavani K

2015-01-01

Refugees are at high risk for communicable diseases due to overcrowding and poor water, sanitation, and hygiene conditions. Handwashing with soap removes pathogens from hands and reduces disease risk. A hepatitis E outbreak in the refugee camps of Maban County, South Sudan in 2012 prompted increased hygiene promotion and improved provision of soap, handwashing stations, and latrines. We conducted a study 1 year after the outbreak to assess the knowledge, attitudes, and practices of the refugees in Maban County. We conducted a cross sectional survey of female heads of households in three refugee camps in Maban County. We performed structured observations on a subset of households to directly observe their handwashing practices at times of possible pathogen transmission. Of the 600 households interviewed, nearly all had soap available and 91 % reported water was available "always" or "sometimes". Exposure to handwashing promotion was reported by 85 % of the respondents. Rinsing hands with water alone was more commonly observed than handwashing with soap at critical handwashing times including "before eating" (80 % rinsing vs. 7 % washing with soap) and "before preparing/cooking food" (72.3 % vs 23 %). After toilet use, 46 % were observed to wash hands with soap and an additional 38 % rinsed with water alone. Despite intensive messaging regarding handwashing with soap and access to soap and water, rinsing hands with water alone rather than washing hands with soap remains more common among the refugees in Maban County. This practice puts them at continued risk for communicable disease transmission. Qualitative research into local beliefs and more effective messaging may help future programs tailor handwashing interventions.

Soap-film coating: High-speed deposition of multilayer nanofilms

PubMed Central

Zhang, Renyun; Andersson, Henrik A.; Andersson, Mattias; Andres, Britta; Edlund, Håkan; Edström, Per; Edvardsson, Sverker; Forsberg, Sven; Hummelgård, Magnus; Johansson, Niklas; Karlsson, Kristoffer; Nilsson, Hans-Erik; Norgren, Magnus; Olsen, Martin; Uesaka, Tetsu; Öhlund, Thomas; Olin, Håkan

2013-01-01

The coating of thin films is applied in numerous fields and many methods are employed for the deposition of these films. Some coating techniques may deposit films at high speed; for example, ordinary printing paper is coated with micrometre-thick layers of clay at a speed of tens of meters per second. However, to coat nanometre thin films at high speed, vacuum techniques are typically required, which increases the complexity of the process. Here, we report a simple wet chemical method for the high-speed coating of films with thicknesses at the nanometre level. This soap-film coating technique is based on forcing a substrate through a soap film that contains nanomaterials. Molecules and nanomaterials can be deposited at a thickness ranging from less than a monolayer to several layers at speeds up to meters per second. We believe that the soap-film coating method is potentially important for industrial-scale nanotechnology. PMID:23503102

Numerical Analysis of Transient Temperature Response of Soap Film

NASA Astrophysics Data System (ADS)

Tanaka, Seiichi; Tatesaku, Akihiro; Dantsuka, Yuki; Fujiwara, Seiji; Kunimine, Kanji

2015-11-01

Measurements of thermophysical properties of thin liquid films are important to understand interfacial phenomena due to film structures composed of amphiphilic molecules in soap film, phospholipid bilayer of biological cell and emulsion. A transient hot-wire technique for liquid films less than 1 \\upmu m thick such as soap film has been proposed to measure the thermal conductivity and diffusivity simultaneously. Two-dimensional heat conduction equations for a solid cylinder with a liquid film have been solved numerically. The temperature of a thin wire with liquid film increases steeply with its own heat generation. The feasibility of this technique is verified through numerical experiments for various thermal conductivities, diffusivities, and film thicknesses. Calculated results indicate that the increase in the volumetric average temperature of the thin wire sufficiently varies with the change of thermal conductivity and diffusivity of the soap film. Therefore, the temperature characteristics could be utilized to evaluate both the thermal conductivity and diffusivity using the Gauss-Newton method.

The fluid trampoline: droplets bouncing on a soap film

NASA Astrophysics Data System (ADS)

Bush, John; Gilet, Tristan

2008-11-01

We present the results of a combined experimental and theoretical investigation of droplets falling onto a horizontal soap film. Both static and vertically vibrated soap films are considered. A quasi-static description of the soap film shape yields a force-displacement relation that provides excellent agreement with experiment, and allows us to model the film as a nonlinear spring. This approach yields an accurate criterion for the transition between droplet bouncing and crossing on the static film; moreover, it allows us to rationalize the observed constancy of the contact time and scaling for the coefficient of restitution in the bouncing states. On the vibrating film, a variety of bouncing behaviours were observed, including simple and complex periodic states, multiperiodicity and chaos. A simple theoretical model is developed that captures the essential physics of the bouncing process, reproducing all observed bouncing states. Quantitative agreement between model and experiment is deduced for simple periodic modes, and qualitative agreement for more complex periodic and chaotic bouncing states.

The Appeal of Soap Opera.

ERIC Educational Resources Information Center

Kielwasser, Alfred P.; Wolf, Michelle A.

This paper provides a framework for developing an approach to understanding soap opera's appeal as a direct function of both the genre's form and of its fans' viewing behavior. The paper suggests that while this analysis is largely critical, other studies from both critical and social scientific approaches can be based upon the framework and…

Soap production: A green prospective.

PubMed

Félix, Sandra; Araújo, Joana; Pires, Ana Maria; Sousa, Ana Cláudia

2017-08-01

A green prospective based on the reuse of waste materials such as almond shells, orange peel and used cooking oil to manufacture soap is presented. In Portugal, thousands of tons of waste are generated from used cooking oil and production of nut shells' residues is growing every year. In addition, the high consumption of citrus fruits, oranges in particular, generates large amounts of citrus peel. Therefore, it is necessary to diversify reuse mechanisms of these wastes, in order to make them back into raw materials. Complying with this trend, this work was carried out by processing and grinding almond shells, treating used oil, processing orange peels and extracting limonene, formulating and producing soap, and performing an acceptance study of the final product. Results validated a high potential of the idea in the field of environmental education, so it can be replicated in practical classes. It can also be useful for waste management, and it can support the development of community projects on an ecological approach. Copyright © 2017 Elsevier Ltd. All rights reserved.

Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents.

PubMed

Geraldo, Ingrid M; Gilman, Allan; Shintre, Milind S; Modak, Shanta M

2008-08-01

To evaluate the antimicrobial efficacy of and risk of organisms developing resistance to 2 novel hand soaps: (1) a soap containing triclosan, polyhexamethylene biguanide, and benzethonium chloride added to a soap base (TPB soap); and (2) a soap containing farnesol, polyhexamethylene biguanide, and benzethonium chloride added to a soap base (FPB soap). Tests also included soaps containing only triclosan. The risk of emergence of resistant bacterial mutants was investigated by determining the susceptibility changes after repeated exposure of bacteria to the drugs and soaps in vitro. The effectiveness of the soaps was evaluated using an in vitro tube dilution method, a volunteer method (the ASTM standard), and 2 pig skin methods. The minimum inhibitory concentration and minimum bactericidal concentration of triclosan against Staphylococcus aureus increased 8- to 62.5-fold, whereas those of TPB and FPB (both alone and in soap) were unchanged. In vitro, TPB and FPB soaps produced higher log(10) reductions in colony-forming units of all tested organisms (4.95-8.58) than did soaps containing triclosan alone (0.29-4.86). In the test using the pig skin and volunteer methods, TPB soap produced a higher log(10) reduction in colony-forming units (3.1-3.3) than did the soap containing triclosan alone (2.6-2.8). The results indicate that TPB and FPB soaps may provide superior rapid and broad-spectrum efficacy with a lower risk of organisms developing resistance than do soaps containing triclosan alone. Pig skin methods may be used to predict the efficacy of antibacterial soaps in the rapid disinfection of contaminated hands. Hand washing with TPB and FPB soaps by healthcare workers and the general population may reduce the transmission of pathogens, with a lower risk of promoting the emergence of resistant organisms.

[Microbiological characteristics of selected liquid soaps for hands washing].

PubMed

Tyski, Stefan; Bocian, Ewa; Zawistowska, Anna; Mrówka, Agnieszka; Kruszewska, Hanna; Grzybowska, Wanda; Zareba, Tomasz

2013-01-01

According to common belief, supported by the authority of the World Health Organization - WHO, the common (social) hand washing is the simplest, cheapest and the most effective way of reduction the hospital-acquired infections. For this purpose products of"liquid soaps", present in a large number on the market, are most often applied. Microbiological status (microbiological purity and antimicrobial activity) of"liquid soaps" available on the Polish market is not known, because relevant routinely studies have not been performed. Only the antibacterial and / or antifungal activity of certain formulations is sometimes assessed, especially when the manufacturer suggests the standardized application of the products for surgical or hygienic procedures. The aim of this study was to determine the microbiological quality, especially microbiological purity and antimicrobial activity of the selected hands washing products, presents on the Polish market. The 12 selected commercial products, available on the market in Poland, dedicated for hands washing were included into study. Microbiological purity test was carried out in accordance with the Polish Pharmacopoeia (FP) monograph (FP monograph numbers correspond to numbers of the European Pharmacopoeia monograph- Ph. Eur.) No 2.6.12 "Microbiological examination of non-sterile products: microbial enumaration tests", and the monograph of FP No. 2.6.13 "Microbiological examination of non-sterile products: test for specified microorganisms". The following physico-chemical properties of soaps were examined: the pH of the formulations was measured according to the monograph FP No. 2.2.3. "Potentiometric determination of pH", the density of products was assayed according to the monograph FPNo. 2.2.5. "Relative density" and determination the water activity was performed by monograph FP No 2.9.39 "Water-solid interactions: determination of sorption-desorption isotherms and of water activity". Next, antibacterial and antifungal

Evaluation of proposed Skylab and SSP soap products.

NASA Technical Reports Server (NTRS)

Durfee, R. L.; Spurlock, J. M.; Whitmore, F. C.

1973-01-01

Four candidate cleansing agents evaluated in terms of potential hazards to crew members included two soaps (Neutrogena bar soap and Olive Leaf Liquid), one nonfoaming surfactant (Miranol JEM), and one laundry detergent (sodium dodecylbenzene sulfonate). None of the four exhibited adverse dermatological effects from skin patch tests or supported growth of potentially pathogenic microorganisms. Aqueous solutions of Neutrogena did support a mold species. Neutrogena and Miranol JEM were used in a simulated Skylab personal hygiene regimen with no adverse effects on skin or skin microflora. Based on our results, each of these agents appear to be a promising candidate material for the use intended.

Determination of surface tension from the measurement of internal pressure of mini soap bubbles

NASA Astrophysics Data System (ADS)

Behroozi, F.; Behroozi, P. S.

2011-11-01

We review the elementary theory that gives the internal pressure of a soap bubble in terms of its radius and surface tension. The theory is generalized to relate the pressure difference across any element of a soap film to its local curvature. This result is used to introduce the concept of the mean curvature of a surface element and is applied to a double soap bubble to obtain the relation between the three radii that characterize its geometry. We also describe a simple setup, suitable for the undergraduate laboratory, to produce mini bubbles and to obtain the surface tension of the soap solution by measuring the radius and internal pressure of the bubbles.

Improved sample treatment for the determination of insoluble soap in sewage sludge samples by liquid chromatography with fluorescence detection.

PubMed

Cantarero, Samuel; Zafra-Gómez, A; Ballesteros, O; Navalón, A; Vílchez, J L; Crovetto, G; Verge, C; de Ferrer, J A

2010-09-15

A new selective and sensitive method for the determination of insoluble fatty acid salts (soap) in sewage sludge samples is proposed. The method involves a clean up of sample with petroleum ether, the conversion of calcium and magnesium insoluble salts into soluble potassium salts, potassium salts extraction with methanol, and a derivatization procedure previous to the liquid chromatography with fluorescence detection (LC-FLD) analysis. Three different extraction techniques (Soxhlet, microwave-assisted extraction and ultrasounds) were compared and microwave-assisted extraction (MAE) was selected as appropriate for our purpose. This allowed to reduce the extraction time and solvent waste (50 mL of methanol in contrast with 250 mL for Soxhlet procedure). The absence of matrix effect was demonstrated with two standards (C(13:0) and C(17:0)) that are not commercials and neither of them has been detected in sewage sludge samples. Therefore, it was possible to evaluate the matrix effect since both standards have similar environmental behaviour (adsorption and precipitation) to commercial soaps (C(10:0)-C(18:0)). The method was successfully applied to samples from different sources and consequently, with different composition. Copyright (c) 2010 Elsevier B.V. All rights reserved.

A meta-analysis of the published literature on the effectiveness of antimicrobial soaps.

PubMed

Montville, Rebecca; Schaffner, Donald W

2011-11-01

The goal of this research was to conduct a systematic quantitative analysis of the existing data in the literature in order to determine if there is a difference between antimicrobial and nonantimicrobial soaps and to identify the methodological factors that might affect this difference. Data on hand washing efficacy and experimental conditions (sample size, wash duration, soap quantity, challenge organism, inoculum size, and neutralization method) from published studies were compiled and transferred to a relational database. A total of 25 publications, containing 374 observations, met the study selection criteria. The majority of the studies included fewer than 15 observations with each treatment and included a direct comparison between nonantimicrobial soap and antimicrobial soap. Although differences in efficacy between antimicrobial and nonantimicrobial soap were small (∼0.5-log CFU reduction difference), antimicrobial soap produced consistently statistically significantly greater reductions. This difference was true for any of the antimicrobial compounds investigated where n was >20 (chlorhexidine gluconate, iodophor, triclosan, or povidone). Average log reductions were statistically significantly greater (∼2 log CFU) when either gram-positive or gram-negative transient organisms were deliberately added to hands compared with experiments done with resident hand flora (∼0.5 log CFU). Our findings support the importance of using a high initial inoculum on the hands, well above the detection limit. The inherent variability in hand washing seen in the published literature underscores the importance of using a sufficiently large sample size to detect differences when they occur.

Use of a lactic acid plus lactoserum intimate liquid soap for external hygiene in the prevention of bacterial vaginosis recurrence after metronidazole oral treatment.

PubMed

Bahamondes, M Valeria; Portugal, Priscila Mendes; Brolazo, Eliane Melo; Simões, José Antônio; Bahamondes, Luis

2011-01-01

To determine the recurrence of bacterial vaginosis (BV) after the use of a lactic acid plus lactoserum liquid soap starting immediately after the treatment with oral metronidazole and the quality of life of the participants. A total of 123 women with diagnosis of BV with at least three of the following criteria: 1) homogeneous vaginal discharge without inflammation of the vagina or vulva; 2) vaginal pH ≥ 4.5; 3) positive Whiff test; and 4) "clue cells" in more than 20% of the epithelial cells in the vagina. A Nugent score ≥ 4 in the vaginal bacterioscopy was also used. After BV diagnosis, metronidazole 500 mg was administered orally bid during 7 days. Patients cured of BV were then instructed to use 7.5 to 10 mL of a lactic acid plus lactoserum liquid soap once-a-day for hygiene of the external genital region. Three subsequent control visits after starting the hygiene treatment (30, 60, and 90 days; ± 5 days) were scheduled. A questionnaire was applied in the form of visual analogue scale (VAS) in all the visits regarding: 1) level of comfort at the genital region; 2) malodorous external genitalia; 3) comfort in sexual intercourse; 4) satisfaction with intimate hygiene; and 5) self-esteem. Ninety two (74.8%) women initiated the use of a lactic acid plus lactoserum liquid soap at visit 1. At visit 2, 3, and 4 there were 84, 62 and 42 women available for evaluation, respectively. The rate of recurrence of BV was 19.0%, 24.2% and 7.1%, respectively in the three visits and vaginal candidiasis was observed in five treated women. Quality of life was evaluated in the 42 women who completed the four visits schedule and there were significant improvement in the five domains assessed. A lactic acid plus lactoserum liquid soap for external intimate hygiene may be an option for the prevention of BV recurrence after treatment and cure with oral metronidazole.

Antimicrobial Activity of Medicated Soaps Commonly Used By Dar es Salaam Residents in Tanzania

PubMed Central

Mwambete, K. D.; Lyombe, F.

2011-01-01

An in vitro evaluation of the anti-microbial activity of medicated soaps was conducted using ditch-plate and hand washing techniques. Strains of reference microbes namely Candida albicans (ATCC90028), Staphylococcus aureus (ATCC25923), Pseudomonas aureginosa (ATCC27853) and Escherichia coli (ATCC25922) were tested at three different soaps’ concentrations (1.0, 4.0 and 8.0 mg/ml). A total of 16 medicated soaps were assayed for their antimicrobial efficacy. Of these, 13 were medicated and 3 non-medicated soaps, which served as control. Ciprofloxacin and ketaconazole were employed as positive controls. Label disclosure for the soaps’ ingredients and other relevant information were absorbed. The most common antimicrobial active ingredients were triclosan, trichloroxylenol and trichlorocarbanilide. ANOVA for means of zones of inhibition revealed variability of antimicrobial activity among the medicated soaps. Positive correlation (r=0.318; P<0.01) between zones of inhibition and soaps’ concentrations was evidenced. Hand washing frequencies positively correlated with microbial counts. Roberts® soap exhibited the largest zone of inhibition (34 mm) on S. aureus. Candida albicans was the least susceptible microbe. Regency® and Dalan® exhibited the least zone of inhibition on the tested bacteria. Protex®, Roberts®, Family® and Protector® were equally effective (P<0.01) against S. aureus. In conclusion, majority of the assayed medicated soaps have satisfactory antibacterial activity; though lack antifungal effect with exception of Linda® liquid soap. The hand washing technique has proved to be inappropriate for evaluation of soaps’ antimicrobial efficacy due to presence of the skin microflora. PMID:22131630

The microjet-film interaction: the interaction and resulting shapes of a liquid microjet impacting a soap film

NASA Astrophysics Data System (ADS)

Chan, Jau Tung; Lee, Jie Liang; Tjeng, Vincent; Yeo, Ye; Tan, Guoxian

2014-11-01

The International Young Physicists’ Tournament (IYPT) is a worldwide annual competition for high-school students. This paper is adapted from the solution to problem 8, Jet and Film, as presented by the Singapore Team at the 26th IYPT, Taipei, Taiwan. The impact of liquid microjets on stable soap films was investigated. Two steady regimes were observed: refraction (where the microjet penetrates the soap film and is deflected) and absorption (where the microjet merges with the soap film and forms vertical undulating patterns on the soap film surface). This phenomenon has potential applications in controlling the trajectory of a liquid microjet in air. Although Kirstetter et al (2012) investigated this interaction by using the same liquid for both the microjet and the soap film, this paper extends their work by using different liquids for the microjet and the soap film. In addition, the need for a small-angle approximation of Snell’s law is removed for the refraction regime, and an alternative expression is proposed for the force exerted by the soap film on the microjet in the absorption regime that accounts for the dependence of the wavelength of the undulating patterns on the angle of incidence of the microjet on the soap film. Empirical data support these improved theoretical predictions.

Elemental and Molecular Segregation in Oil Paintings due to Lead Soap Degradation.

PubMed

Chen-Wiegart, Yu-Chen Karen; Catalano, Jaclyn; Williams, Garth J; Murphy, Anna; Yao, Yao; Zumbulyadis, Nicholas; Centeno, Silvia A; Dybowski, Cecil; Thieme, Juergen

2017-09-14

The formation of Pb, Zn, and Cu carboxylates (soaps) has caused visible deterioration in hundreds of oil paintings dating from the 15th century to the present. Through transport phenomena not yet understood, free fatty acids in the oil binding medium migrate through the paint and react with pigments containing heavy metals to form soaps. To investigate the complex correlation among the elemental segregation, types of chemical compounds formed, and possible mechanisms of the reactions, a paint sample cross-section from a 15th century oil painting was examined by synchrotron X-ray techniques. X-ray fluorescence (XRF) microscopy, quantified with elemental correlation density distribution, showed Pb and Sn segregation in the soap-affected areas. X-ray absorption near edge structure (XANES) around the Pb-L3 absorption edge showed that Pb pigments and Pb soaps can be distinguished while micro-XANES gave further information on the chemical heterogeneity in the paint film. The advantages and limitations of these synchrotron-based techniques are discussed and compared to those of methods routinely used to analyze paint samples. The results presented set the stage for improving the information extracted from samples removed from works of art and for correlating observations in model paint samples to those in the naturally aged samples, to shed light onto the mechanism of soap formation.

Elemental and Molecular Segregation in Oil Paintings due to Lead Soap Degradation

DOE PAGES

Chen-Wiegart, Yu-chen Karen; Catalano, Jaclyn; Williams, Garth J.; ...

2017-09-14

The formation of Pb, Zn, and Cu carboxylates (soaps) has caused visible deterioration in hundreds of oil paintings dating from the 15th century to the present. Through transport phenomena not yet understood, free fatty acids in the oil binding medium migrate through the paint and react with pigments containing heavy metals to form soaps. To investigate the complex correlation among the elemental segregation, types of chemical compounds formed, and possible mechanisms of the reactions, a paint sample cross-section from a 15th century oil painting was examined by synchrotron X-ray techniques. X-ray fluorescence (XRF) microscopy, quantified with elemental correlation density distribution,more » showed Pb and Sn segregation in the soap-affected areas. X-ray absorption near edge structure (XANES) around the Pb-L3 absorption edge showed that Pb pigments and Pb soaps can be distinguished while micro-XANES gave further information on the chemical heterogeneity in the paint film. The advantages and limitations of these synchrotron-based techniques are discussed and compared to those of methods routinely used to analyze paint samples. The results presented set the stage for improving the information extracted from samples removed from works of art and for correlating observations in model paint samples to those in the naturally aged samples, to shed light onto the mechanism of soap formation.« less

Elemental and Molecular Segregation in Oil Paintings due to Lead Soap Degradation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen-Wiegart, Yu-chen Karen; Catalano, Jaclyn; Williams, Garth J.

The formation of Pb, Zn, and Cu carboxylates (soaps) has caused visible deterioration in hundreds of oil paintings dating from the 15th century to the present. Through transport phenomena not yet understood, free fatty acids in the oil binding medium migrate through the paint and react with pigments containing heavy metals to form soaps. To investigate the complex correlation among the elemental segregation, types of chemical compounds formed, and possible mechanisms of the reactions, a paint sample cross-section from a 15th century oil painting was examined by synchrotron X-ray techniques. X-ray fluorescence (XRF) microscopy, quantified with elemental correlation density distribution,more » showed Pb and Sn segregation in the soap-affected areas. X-ray absorption near edge structure (XANES) around the Pb-L3 absorption edge showed that Pb pigments and Pb soaps can be distinguished while micro-XANES gave further information on the chemical heterogeneity in the paint film. The advantages and limitations of these synchrotron-based techniques are discussed and compared to those of methods routinely used to analyze paint samples. The results presented set the stage for improving the information extracted from samples removed from works of art and for correlating observations in model paint samples to those in the naturally aged samples, to shed light onto the mechanism of soap formation.« less

Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP).

PubMed

Vincent, Jean-Louis; Lefrant, Jean-Yves; Kotfis, Katarzyna; Nanchal, Rahul; Martin-Loeches, Ignacio; Wittebole, Xavier; Sakka, Samir G; Pickkers, Peter; Moreno, Rui; Sakr, Yasser

2018-03-01

To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those in the SOAP study. The ICON patients were older (62.5 ± 17.0 vs. 60.6 ± 17.4 years) and had higher severity scores than the SOAP patients. The proportion of patients with sepsis at any time during the intensive care unit stay was slightly higher in the ICON study (31.9 vs. 29.6%, p = 0.03). In multilevel analysis, the adjusted odds of ICU mortality were significantly lower for ICON patients than for SOAP patients, particularly in patients with sepsis [OR 0.45 (0.35-0.59), p < 0.001]. Over the 10-year period between 2002 and 2012, the proportion of patients with sepsis admitted to European ICUs remained relatively stable, but the severity of disease increased. In multilevel analysis, the odds of ICU mortality were lower in our 2012 cohort compared to our 2002 cohort, particularly in patients with sepsis.

16. 3RD FLOOR, J.M. LEHMANN CO. FIVEROLL TOILET SOAP MILL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

16. 3RD FLOOR, J.M. LEHMANN CO. FIVE-ROLL TOILET SOAP MILL INSTALLED 1950, TO WEST; BUCKET CONVEYOR AT RIGHT MOVED WASTE FROM 2ND FLOOR SOAP PRESSES TO 5TH FLOOR RE-MANUFACTURE - Colgate & Company Jersey City Plant, Building No. B-14, 54-58 Grand Street, Jersey City, Hudson County, NJ

SOAP Methodology in General Practice/Family Medicine Teaching in Practical Context.

PubMed

Santiago, Luiz Miguel; Neto, Isabel

2016-12-30

Medical records in General Practice/Family Medicine are an essential information support on the health status of the patient and a communication document between health professionals. The development of competencies in General Practice/Family Medicine during pre-graduation must include the ability to make adequate medical records in practical context. As of 2012, medicine students at the University of Beira Interior have been performing visits using the Subjective, Objective, Assessment and Plan - SOAP methodology, with a performance evaluation of the visit, with the aim to check on which Subjective, Objective, Assessment and Plan - SOAP aspects students reveal the most difficulties in order to define improvement techniques and to correlate patient grade with tutor evaluation. Analysing the evaluation data for the 2015 - 2016 school year at the General Practice/Family Medicine visit carried out by fourth year students in medicine, comparing the averages of each item in the Subjective, Objective, Assessment and Plan - SOAP checklist and the patient evaluation. In the Subjective, Objective, Assessment and Plan - SOAP, 29.7% of students are on the best grade quartile, 37.1% are on the best competencies quartile and 27.2% on the best patient grade quartile. 'Evolution was verified/noted' received the worst grades in Subjective, 'Record of physical examination focused on the problem of the visit' received the worst grades in Objective, 'Notes of Diagnostic reasoning / differential diagnostic' received de worst grades in Assessment and 'Negotiation of aims to achieve' received the worst grades in Plan. The best tutor evaluation is found in 'communication'. Only one single study evaluated student´s performance under examination during a visit, with similar results to the present one and none addressed the patient's evaluation. Students revealed a good performance in using the Subjective, Objective, Assessment and Plan - SOAP. The findings represent the beginning of the

21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Detergent substances, other than soap, intended... Ingredients § 701.20 Detergent substances, other than soap, intended for use in cleansing the body. (a) In its definition of the term cosmetic, the Federal Food, Drug, and Cosmetic Act specifically excludes soap. The...

21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Detergent substances, other than soap, intended... Ingredients § 701.20 Detergent substances, other than soap, intended for use in cleansing the body. (a) In its definition of the term cosmetic, the Federal Food, Drug, and Cosmetic Act specifically excludes soap. The...

21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Detergent substances, other than soap, intended... Ingredients § 701.20 Detergent substances, other than soap, intended for use in cleansing the body. (a) In its definition of the term cosmetic, the Federal Food, Drug, and Cosmetic Act specifically excludes soap. The...

Pollution control of industrial wastewater from soap and oil industries: a case study.

PubMed

Abdel-Gawad, S; Abdel-Shafy, M

2002-01-01

Industrial wastewater from soap and oil industries represents a heavy pollution source on their receiving water body. This paper studies a case of pollution control at Tanta Soap and Oil Company, Banha Factory, Egypt. The factory production includes soap, edible oil, and animal fodder. About 4,347 m3/day of industrial wastewater effluent was discharged via gravity sewers to the public sewerage system. Most of the effluent was cooling water because the cooling process in the factory was open circle. In spite of the huge quantity of cooling water being disposed of, disposal of wastewater was violating pertinent legislation. Three procedures were used for controlling the pollution at the Banha Factory. Firstly, all open circuit cooling systems were converted to closed circuit thus reducing the quantity of the discharged wastewater down to 767 m3/day. Secondly, the heavily polluted oil and grease (O&G) wastewater from the refinery unit is treated via two gravity oil separator (GOS) units, dissolved air floatation (DAF), and biological units in order to reduce the high levels of O&G, BOD, COD, and SS to the allowable limits. Thirdly, the heavily polluted waste effluent from the 'red water' saponification unit is treated separately by acidification to convert the emulsified fatty acid to free form in order to be separated through an oil separation unit. The effluent is then passed to liming stage to neutralize excess acidity and precipitate some of the dissolved matters. The mixture is finally clarified and the pH is adjusted to the allowable limits. The effluent wastewater from the three processes is collected and mixed in a final equalization tank for discharging effluent to the public sewerage system. The characteristics of the effluent water are very good with respect to the allowable Egyptian limits for discharging effluent to the public sewerage system.

40 CFR 430.03 - Best management practices (BMPs) for spent pulping liquor, soap, and turpentine management, spill...

Code of Federal Regulations, 2014 CFR

2014-07-01

... spent pulping liquor, soap, and turpentine management, spill prevention, and control. 430.03 Section 430... management practices (BMPs) for spent pulping liquor, soap, and turpentine management, spill prevention, and... Liquor, Soap, and Turpentine Service: Any process vessel, storage tank, pumping system, evaporator, heat...

40 CFR 430.03 - Best management practices (BMPs) for spent pulping liquor, soap, and turpentine management, spill...

Code of Federal Regulations, 2013 CFR

2013-07-01

... spent pulping liquor, soap, and turpentine management, spill prevention, and control. 430.03 Section 430... management practices (BMPs) for spent pulping liquor, soap, and turpentine management, spill prevention, and... Liquor, Soap, and Turpentine Service: Any process vessel, storage tank, pumping system, evaporator, heat...

[Identification of bacterial contamination in liquid soap for hospital use].

PubMed

Caetano, Joselany Afio; Lima, Maria Alzete; Di Ciero Miranda, Maira; Serufo, José Carlos; Ponte, Paulo Roberto Lins

2011-03-01

This study performed a bacteriological analysis of the liquid soap in dispensers that health professionals use for hand washing. This exploratory, cross-sectional study was developed at the hospitalization units of a medium-sized hospital in Fortaleza, Ceará, Brazil. Data were collected between May and July 2007. Fifty-nine liquid soap dispensers were analyzed, of which 33 contained the following microorganisms: Burkholderia cepacia (14), Pseudomonas putidas (9), Pseudomonas aeruginosa (3), Klebsiella pneumoniae (3), Enterobacter clocae (2), and Pseudomonas luteola (2). The units with the largest number of contaminated samples were the surgical (n=7) and the dermatological clinics (n=4). Contamination was also found in an original flask of the same lot of liquid soap used to fill up the dispensers. In conclusion, there is a need to regulate and control the quality of these products in the production lines as well as during use in hospital services, mainly because they are used to prevent hospital infection.

10. 4TH FLOOR, HOTEL SOAP LINE No. 6 TO SOUTHWEST, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. 4TH FLOOR, HOTEL SOAP LINE No. 6 TO SOUTHWEST, WITH AUTOMATIC CUTTER (LEFT), PRESS (CENTER), AND WRAPPER (RIGHT); LARGE CHUTE AT CENTER FROM 5TH FLOOR BINS TO 3RD FLOOR SOAP MILLS; OVERHEAD AND FLOOR (LOWER RIGHT) FINISHED GOODS CONVEYORS TO G BLOCK (HAER NO. NJ-71-NN) - Colgate & Company Jersey City Plant, Building No. B-14, 54-58 Grand Street, Jersey City, Hudson County, NJ

Hand soap contamination by Pseudomonas aeruginosa in a tertiary care hospital: no evidence of impact on patients.

PubMed

Blanc, D S; Gomes Magalhaes, B; Abdelbary, M; Prod'hom, G; Greub, G; Wasserfallen, J B; Genoud, P; Zanetti, G; Senn, L

2016-05-01

During an environmental investigation of Pseudomonas aeruginosa in intensive care units, the liquid hand soap was found to be highly contaminated (up to 8 × 10(5)cfu/g) with this pathogen. It had been used over the previous five months and was probably contaminated during manufacturing. To evaluate the burden of this contamination on patients by conducting an epidemiological investigation using molecular typing combined with whole genome sequencing (WGS). P. aeruginosa isolates from clinical specimens were analysed by double locus sequence typing (DLST) and compared with isolates recovered from the soap. Medical charts of patients infected with a genotype identical to those found in the soap were reviewed. WGS was performed on soap and patient isolates sharing the same genotype. P. aeruginosa isolates (N = 776) were available in 358/382 patients (93.7%). Only three patients (0.8%) were infected with a genotype found in the soap. Epidemiological investigations showed that the first patient was not exposed to the soap, the second could have been exposed, and the third was indeed exposed. WGS showed a high number of core single nucleotide polymorphism differences between patients and soap isolates. No close genetic association was observed between soap and patient isolates, ruling out the hypothesis of transmission. Despite a highly contaminated soap, the combined investigation with DLST and WGS ruled out any impact on patients. Hand hygiene performed with alcohol-based solution for >15 years was probably the main reason. However, such contamination represents a putative reservoir of pathogens that should be avoided in the hospital setting. Copyright © 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Motion of Colloidal Particles near Plateau Border in Freely Suspended Soap Film

NASA Astrophysics Data System (ADS)

Pak, Hyuk Kyu; Sur, Jeanman

2000-03-01

We study the motion of colloidal particle near Plateau border in free-standing soap film which is placed perpendicularly to the gravitational direction. When the thickness of soap film is a micron order, two air/water interfacial surfaces of the film can be deformed by the presence of the colloidal particle. When the colloidal particles are in the central area of soap film, they move in random directions. But, as the particles approach near Plateau border, they are accelerated to the border of the film. The travelling distance, before the accelerated particle stops, depends on particle size. We propose a simple model to explain the motion of particle near Plateau border using a surface energy argument and compare the results with experimental measurements.

Role of surface elasticity in the drainage of soap films

NASA Astrophysics Data System (ADS)

Sonin, A. A.; Bonfillon, A.; Langevin, D.

1993-10-01

We present measurements of the thinning velocity of circular horizontal soap films made from dilute surfactant solutions (around the critical micellar concentration). We have solved numerically the hydrodynamic equations for the drainage process. After data fitting, we deduce the values of the elasticities of the surfactant monolayer that stabilizes the soap film. These elasticity values have been compared to elasticities obtained independently from the study of waves at the surface of the solution. The comparison reveals the importance of surface convection in the drainage process and demonstrates the important role of surface elasticity.

Thermotropic phase behavior of choline soaps.

PubMed

Klein, Regina; Dutton, Helen; Diat, Olivier; Tiddy, Gordon J T; Kunz, Werner

2011-04-14

Choline carboxylates (ChCm with m = 12-18) are simple biocompatible anionic surfactants with very low Krafft temperatures, possessing a rich aqueous phase behavior. In the present work, we have investigated the thermotropic mesomorphism of anhydrous ChCm salts for m = 12-18. Transition temperatures and enthalpies determined by differential scanning calorimetry reveal that all investigated compounds exhibit three different phases between -20 and 95 °C. The phases were further characterized by optical polarizing microscopy, NMR spin-spin relaxation, and X-ray scattering measurements. The nature of the phases was identified with increasing temperature as crystalline, semicrystalline, and liquid-crystalline lamellar. Even long-chain choline carboxylates (m = 18) were found to melt into a lamellar liquid-crystalline phase below 100 °C. Accordingly, with choline as counterion in simple fatty acid soaps, not only the water solubility is considerably enhanced but also the melting points are substantially reduced, hence facilitating thermotropic mesomorphism at temperatures between 35 and 95 °C. Thus, simple choline soaps with m = 12-18 may be classified as ionic liquids.

Formation of soap bubbles by gas jet

NASA Astrophysics Data System (ADS)

Zhou, Maolei; Li, Min; Chen, Zhiyuan; Han, Jifeng; Liu, Dong

2017-12-01

Soap bubbles can be easily generated by various methods, while their formation process is complicated and still worth studying. A model about the bubble formation process was proposed in the study by Salkin et al. [Phys. Rev. Lett. 116, 077801 (2016)] recently, and it was reported that the bubbles were formed when the gas blowing velocity was above one threshold. However, after a detailed study of these experiments, we found that the bubbles could be generated in two velocity ranges which corresponded to the laminar and turbulent gas jet, respectively, and the predicted threshold was only effective for turbulent gas flow. The study revealed that the bubble formation was greatly influenced by the aerodynamics of the gas jet blowing to the film, and these results will help to further understand the formation mechanism of the soap bubble as well as the interaction between the gas jet and the thin liquid film.

Columnar to Nematic Mesophase Transition: Binary Mixtures of Copper Soaps with Hydrocarbons

NASA Astrophysics Data System (ADS)

Seghrouchni, R.; Skoulios, A.

1995-09-01

Copper (II) soaps are known to produce columnar mesophases at high temperatures. The polar groups of the soap molecules are stacked over one another within columns surrounded by the paraffin chains in a disordered conformation and laterally arranged according to a two-dimensional hexagonal lattice. Upon addition of a hydrocarbon, the mesophases swell homogeneously. The hydrocarbon molecules locate themselves among the disordered chains of the soap molecules, the columnar cores remain perfectly unchanged, keeping a constant intra-columnar stacking period, and the hexagonal lattice expands in proportion to the amount of hydrocarbon added to the system. Beyond a certain degree of swelling, the columnar mesophases suddenly turn into a nematic mesophase through a first-order phase transition. The structural elements that align parallel to the nematic director are the very same molecular columns that are involved in the columnar mesophases. The columnar to nematic mesophase transition was studied systematically as a function of the molecular size of the soaps and hydrocarbons used as diluents and discussed on a molecular level, emphasizing such aspects as the persistence length of the paraffin chains and the location of the solvent molecules among the columns.

Making Connections in Math: Activating a Prior Knowledge Analogue Matters for Learning

ERIC Educational Resources Information Center

Sidney, Pooja G.; Alibali, Martha W.

2015-01-01

This study investigated analogical transfer of conceptual structure from a prior-knowledge domain to support learning in a new domain of mathematics: division by fractions. Before a procedural lesson on division by fractions, fifth and sixth graders practiced with a surface analogue (other operations on fractions) or a structural analogue (whole…

Popular soap opera helps raise contraceptive use. Tanzania.

PubMed

1996-01-01

The latest Demographic and Health Surveys Report on Knowledge, Attitudes, and Practice documents an increase in the level of use of modern contraceptive methods in Tanzania between 1991 and 1994 from 5.9% to 11.3% of reproductive-age women. 53.2% of all women of reproductive age were exposed to mass media messages about family planning, which large majorities of men and women consider acceptable. 48.3% were exposed through radio, 22.9% reported listening to the US Agency for International Development-funded family planning promotional radio soap opera "Zinduka]", 22.5% read newspaper items, 17.5% saw posters, and 7.3% saw leaflets. 4.5% were visited by a family planning worker, 24.7% discussed family planning with a friend or relative, and 24.7% discussed family planning with health facility personnel. Zinduka], a popular 52-episode soap opera, depicts how the lives of Bomu wa Kabuma's family, in Msongano Town and Tawanya village in Tanzania, are affected because he is unable to provide for his eight children, parents, wife, mistress, and the mistress's child. The soap was produced with technical assistance from the Johns Hopkins University Center for Communication Programs Population Communication Services project. The 15-minute episodes were first broadcast in Swahili on Radio Tanzania from October 1993 through October 1994. The series was then resumed in September 1995 for another 12 months.

Soap Films and GeoGebra in the Study of Fermat and Steiner Points

ERIC Educational Resources Information Center

Flores, Alfinio; Park, Jungeun

2018-01-01

We discuss how mathematics and secondary mathematics education majors developed an understanding of Fermat points for the triangle as well as Steiner points for the square and regular pentagon, and also of soap film configurations between parallel plates where forces are in equilibrium. The activities included the use of soap films and the…

Effects of an entertainment-education radio soap opera on family planning behavior in Tanzania.

PubMed

Rogers, E M; Vaughan, P W; Swalehe, R M; Rao, N; Svenkerud, P; Sood, S

1999-09-01

An entertainment-education radio soap opera introduced in Tanzania in 1993 was evaluated by means of a field experimental design in which the radio program was broadcast by seven mainland stations of Radio Tanzania. An eighth station broadcast alternative programming from 1993 to 1995, its listenership serving as a comparison area in which contemporaneous changes in family planning adoption were measured. The soap opera was subsequently broadcast nationwide from 1995 to 1997. Data about the effects of the radio soap opera were gathered in five annual surveys of about 2,750 households in the comparison and the treatment areas and from a sample of new family planning adopters in 79 health clinics. The soap opera had strong behavioral effects on family planning adoption; it increased listeners' self-efficacy regarding family planning adoption and influenced listeners to talk with their spouses and peers about contraception.

A public study of the lifetime distribution of soap films

NASA Astrophysics Data System (ADS)

Tobin, S. T.; Meagher, A. J.; Bulfin, B.; Möbius, M.; Hutzler, S.

2011-08-01

We present data for the lifetime distribution of soap films made from commercial dish-washing solution and contained in sealed cylinders. Data for over 2500 films were gathered during a 2-month exhibition on the science and art of bubbles and foams in Dublin's Science Gallery. Visitors to the gallery were invited to create 10-20 parallel soap films in acrylic tubes which were sealed with cork stoppers. Individual film bursts occurred at random and were uncorrelated. The total number of remaining films in the tubes was recorded every day. Visitors could monitor the status of their soap film tube and the daily updated histogram of the lifetime of all films. The histogram of the bubble lifetimes is well described by a Weibull distribution, which indicates that the failure rate is not constant and increases over time. Unsealed cylinders show drastically reduced film lifetimes. This experiment illustrates the difference between the unpredictability of the lifetime of individual films and the existence of a well-defined lifetime distribution for the ensemble.

There's alcohol in my soap: portrayal and effects of alcohol use in a popular television series.

PubMed

van Hoof, Joris J; de Jong, Menno D T; Fennis, Bob M; Gosselt, Jordy F

2009-06-01

Two studies are reported addressing the media influences on adolescents' alcohol-related attitudes and behaviours. A content analysis was conducted to investigate the prevalence of alcohol portrayal in a Dutch soap series. The coding scheme covered the alcohol consumption per soap character, drinking situations and drinking times. Inter-coder reliability was satisfactory. The results showed that alcohol portrayal was prominent and that many instances of alcohol use reflected undesirable behaviours. To assess the influence of such alcohol cues on adolescents, a 2x2 experiment was conducted focusing on the separate and combined effects of alcohol portrayal in the soap series and surrounding alcohol commercials. Whereas the alcohol commercials had the expected effects on adolescents' attitudes, the alcohol-related soap content only appeared to have unexpected effects. Adolescents who were exposed to the alcohol portrayal in the soap series had a less positive attitude towards alcohol and lower drinking intentions. Implications of these findings for health policy and future research are discussed.

Spatially-resolved magnetic resonance study of the dissolution interface between soaps and water

NASA Astrophysics Data System (ADS)

Ciampi, E.; Goerke, U.; McDonald, P. J.; Chambers, J. G.; Newling, B.

2002-06-01

The developing interfacial region between a soap bar and water has been studied using a suite of spatially resolved NMR techniques. Stray field imaging (STRAFI) allowed the dynamics of water ingress into a shop-bought, commercial soap to be followed. A simplistic analysis of the data shows the ingress to be a Fickian process (∝t1/2) in the first 4 h. The T2 contrast employed in the STRAFI method is not sufficient to resolve detail of the mesophase formation at the interface. However, double quantum filtered 2H spectroscopy at different positions in the interfacial region allowed water concentration (and mesophase distribution) to be mapped over the first 120 h of dissolution. A simple model shows good agreement with the water concentration data. In the isotropic soap solution above the interfacial region, J-cyclic cross polarization was used to selectively interrogate the CH2 1H of the soap alkyl chains and, in combination with a pulsed field gradient measurement of self-diffusion, suggests a micellar solution in which the hydrodynamic radius of the micelles is ~5nm.

Laser-induced vibration of a thin soap film.

PubMed

Emile, Olivier; Emile, Janine

2014-09-21

We report on the vibration of a thin soap film based on the optical radiation pressure force. The modulated low power laser induces a counter gravity flow in a vertical free-standing draining film. The thickness of the soap film is then higher in the upper region than in the lower region of the film. Moreover, the lifetime of the film is dramatically increased by a factor of 2. Since the laser beam only acts mechanically on the film interfaces, such a film can be employed in an optofluidic diaphragm pump, the interfaces behaving like a vibrating membrane and the liquid in-between being the fluid to be pumped. Such a pump could then be used in delicate micro-equipment, in chips where temperature variations are detrimental and even in biological systems.

The production of paper soaps from coconut oil and Virgin Coconut Oil (VCO) with the addition of glycerine as plasticizer

NASA Astrophysics Data System (ADS)

Widyasanti, Asri; Miracle Lenyta Ginting, Anastasia; Asyifani, Elgina; Nurjanah, Sarifah

2018-03-01

Hand washing with soap is important because it is proven to clean hands from germs and bacteria. The paper soapswere made from coconut oil and virgin coconut oil (VCO) with the addition of glycerin as a plasticizer. The aims of this research were to determine both formulation of paper soap using coconut oil and VCO based with addition of glycerin, and to determine the quality of the paper soapswhich is a disposable hand soap. This research used laboratory experimental method using descriptive analysis. The treatments of this research were treatment A (paper soap without the addition of glycerin), treatment B (paper soap with the addition of glycerin 10% (w/w)), treatment C (paper soap with the addition of glycerin 15% (w/w)), treatment D (paper soap with the addition of glycerin of 20% (w/w)). Parameters tested were moisture content, stability of foam, pH value, insoluble material in ethanol, free alkali content, unsaponified fat, antibacterial activity test, and organoleptic test. The result of physicochemical characteristics for bothcoconut oil-paper soap and VCO-paper soap revealed that treatment C (the addition of glycerin 15% (w/w) was the best soap formulation. Coconut Oil papersoap 15% w/w glicerin had water content 13.72%, the content of insoluble material in ethanol 3.93%, the content of free alkali 0.21%, and the content of unsaponified fat 4.06%, pH value 10.78, stability of foam 97.77%, and antibacterial activity against S. aureus 11.66 mm. Meanwhile, VCO paper soap 15% w/w glicerin had the value of water content of 18.47%, the value stability of foam of 96.7%, the pH value of 10.03, the value of insoluble material in ethanol of 3.49%, the value of free alkali content 0.17%, the value of unsaponified fat 4.91%, and the value of inhibition diameter on the antibacterial activity test 15.28 mm. Based on Mandatory Indonesian National Standard of solid soap SNI 3532:2016 showed that both of paper soap had not been accorded with SNI 3532:2016, unless the

A pilot study on the evaluation of medical student documentation: assessment of SOAP notes.

PubMed

Seo, Ji-Hyun; Kong, Hyun-Hee; Im, Sun-Ju; Roh, HyeRin; Kim, Do-Kyong; Bae, Hwa-Ok; Oh, Young-Rim

2016-06-01

The purpose of this study was evaluation of the current status of medical students' documentation of patient medical records. We checked the completeness, appropriateness, and accuracy of 95 Subjective-Objective-Assessment-Plan (SOAP) notes documented by third-year medical students who participated in clinical skill tests on December 1, 2014. Students were required to complete the SOAP note within 15 minutes of an standard patient (SP)-encounter with a SP complaining rhinorrhea and warring about meningitis. Of the 95 SOAP notes reviewed, 36.8% were not signed. Only 27.4% documented the patient's symptoms under the Objective component, although all students completed the Subjective notes appropriately. A possible diagnosis was assessed by 94.7% students. Plans were described in 94.7% of the SOAP notes. Over half the students planned workups (56.7%) for diagnosis and treatment (52.6%). Accurate documentation of the symptoms, physical findings, diagnoses, and plans were provided in 78.9%, 9.5%, 62.1%, and 38.0% notes, respectively. Our results showed that third-year medical students' SOAP notes were not complete, appropriate, or accurate. The most significant problems with completeness were the omission of students' signatures, and inappropriate documentation of the physical examinations conducted. An education and assessment program for complete and accurate medical recording has to be developed.

Videotaping the Lifespan of a Soap Bubble.

ERIC Educational Resources Information Center

Ramme, Goran

1995-01-01

Describes how the use of a videotape to record the history of a soap bubble allows a study of many interesting events in considerable detail including interference fringes, convection and turbulence patterns on the surface, formation of black film, and the ultimate explosion of the bubble. (JRH)

The use of D-optimal mixture design in optimising okara soap formulation for stratum corneum application.

PubMed

Borhan, Farrah Payyadhah; Abd Gani, Siti Salwa; Shamsuddin, Rosnah

2014-01-01

Okara, soybean waste from tofu and soymilk production, was utilised as a natural antioxidant in soap formulation for stratum corneum application. D-optimal mixture design was employed to investigate the influence of the main compositions of okara soap containing different fatty acid and oils (virgin coconut oil A (24-28% w/w), olive oil B (15-20% w/w), palm oil C (6-10% w/w), castor oil D (15-20% w/w), cocoa butter E (6-10% w/w), and okara F (2-7% w/w)) by saponification process on the response hardness of the soap. The experimental data were utilized to carry out analysis of variance (ANOVA) and to develop a polynomial regression model for okara soap hardness in terms of the six design factors considered in this study. Results revealed that the best mixture was the formulation that included 26.537% A, 19.999% B, 9.998% C, 16.241% D, 7.633% E, and 7.000% F. The results proved that the difference in the level of fatty acid and oils in the formulation significantly affects the hardness of soap. Depending on the desirable level of those six variables, creation of okara based soap with desirable properties better than those of commercial ones is possible.

Influence of Evaporation on Soap Film Rupture.

PubMed

Champougny, Lorène; Miguet, Jonas; Henaff, Robin; Restagno, Frédéric; Boulogne, François; Rio, Emmanuelle

2018-03-13

Although soap films are prone to evaporate due to their large surface to volume ratio, the effect of evaporation on macroscopic film features has often been disregarded in the literature. In this work, we experimentally investigate the influence of environmental humidity on soap film stability. An original experiment allows to measure both the maximum length of a film pulled at constant velocity and its thinning dynamics in a controlled atmosphere for various values of the relative humidity [Formula: see text]. At first order, the environmental humidity seems to have almost no impact on most of the film thinning dynamics. However, we find that the film length at rupture increases continuously with [Formula: see text]. To rationalize our observations, we propose that film bursting occurs when the thinning due to evaporation becomes comparable to the thinning due to liquid drainage. This rupture criterion turns out to be in reasonable agreement with an estimation of the evaporation rate in our experiment.

Pinch-off Scaling Law of Soap Bubbles

NASA Astrophysics Data System (ADS)

Davidson, John; Ryu, Sangjin

2014-11-01

Three common interfacial phenomena that occur daily are liquid drops in gas, gas bubbles in liquid and thin-film bubbles. One aspect that has been studied for these phenomena is the formation or pinch-off of the drop/bubble from the liquid/gas threads. In contrast to the formation of liquid drops in gas and gas bubbles in liquid, thin-film bubble pinch-off has not been well documented. Having thin-film interfaces may alter the pinch-off process due to the limiting factor of the film thickness. We observed the pinch-off of one common thin-film bubble, soap bubbles, in order to characterize its pinch-off behavior. We achieved this by constructing an experimental model replicating the process of a human producing soap bubbles. Using high-speed videography and image processing, we determined that the minimal neck radius scaled with the time left till pinch-off, and that the scaling law exponent was 2/3, similar to that of liquid drops in gas.

Ethical Gifts?: An Analysis of Soap-for-data Transactions in Malawian Survey Research Worlds.

PubMed

Biruk, Crystal

2017-09-01

In 2008, thousands of Malawians received soap from an American research project as a gift for survey participation. Soap was deemed an ethical, non-coercive gift by researchers and ethics boards, but took on meanings that expressed recipients' grievances and aspirations. Research participants reframed soap and research benefits as "rights" they are entitled to, wages for "work," and a symbol of exploitation. Enlisting the perspectives of Malawi's ethics board, demographers, Malawian fieldworkers, and research participants, I describe how soap is spoken about and operates in research worlds. I suggest that neither a prescriptive nor a situated frame for ethics-with their investments in standardization and attention to context, respectively-provides answers about how to compensate Malawian research participants. The conclusion gestures toward a reparative framework for thinking ethics that is responsive not just to project-based parameters but also to the histories and political economy in which projects (and ethics) are situated. © 2017 by the American Anthropological Association.

Lipase pre-hydrolysis enhance anaerobic biodigestion of soap stock from an oil refining industry.

PubMed

Cherif, Slim; Aloui, Fathi; Carrière, Frédéric; Sayadi, Sami

2014-01-01

A novel alcalophilic Staphylococcus haemolyticus strain with the lipolytic activity was used to perform enzymatic hydrolysis pretreatment of soap stock: a lipid rich solid waste from an oil refining industry. The culture liquid of the selected bacteria and an enzymatic preparation obtained by precipitation with ammonium sulphate from a filtrate of the same culture liquid were used for enzymatic pretreatment. The hydrolysis was carried with different incubation concentrations (10, 20 and 30%) of soap stock and the pretreatment efficiency was verified by running comparative biodegradability tests (crude and treated lipid waste). All pretreated assays showed higher reaction rate compared to crude lipid waste, which was confirmed by the increased levels of biogas production. The pretreatment of solutions containing 10% emulsified soap stock was optimized for 24 h hydrolysis time, enabling high-biogaz formation (800 ml). The use of enzymatic pre-treatment seemed to be a very promising alternative for treating soap stock having high fat contents.

40 CFR 467.60 - Applicability; description of the drawing with emulsions or soaps subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Applicability; description of the drawing with emulsions or soaps subcategory. 467.60 Section 467.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Emulsions or Soaps Subcategory...

40 CFR 467.60 - Applicability; description of the drawing with emulsions or soaps subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 30 2011-07-01 2011-07-01 false Applicability; description of the drawing with emulsions or soaps subcategory. 467.60 Section 467.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Emulsions or Soaps Subcategory...

Assessment of SOAP note evaluation tools in colleges and schools of pharmacy.

PubMed

Sando, Karen R; Skoy, Elizabeth; Bradley, Courtney; Frenzel, Jeanne; Kirwin, Jennifer; Urteaga, Elizabeth

2017-07-01

To describe current methods used to assess SOAP notes in colleges and schools of pharmacy. Members of the American Association of Colleges of Pharmacy Laboratory Instructors Special Interest Group were invited to share assessment tools for SOAP notes. Content of submissions was evaluated to characterize overall qualities and how the tools assessed subjective, objective, assessment, and plan information. Thirty-nine assessment tools from 25 schools were evaluated. Twenty-nine (74%) of the tools were rubrics and ten (26%) were checklists. All rubrics included analytic scoring elements, while two (7%) were mixed with holistic and analytic scoring elements. A majority of the rubrics (35%) used a four-item rating scale. Substantial variability existed in how tools evaluated subjective and objective sections. All tools included problem identification in the assessment section. Other assessment items included goals (82%) and rationale (69%). Seventy-seven percent assessed drug therapy; however, only 33% assessed non-drug therapy. Other plan items included education (59%) and follow-up (90%). There is a great deal of variation in the specific elements used to evaluate SOAP notes in colleges and schools of pharmacy. Improved consistency in assessment methods to evaluate SOAP notes may better prepare students to produce standardized documentation when entering practice. Copyright © 2017 Elsevier Inc. All rights reserved.

The Use of D-Optimal Mixture Design in Optimising Okara Soap Formulation for Stratum Corneum Application

PubMed Central

Borhan, Farrah Payyadhah; Abd Gani, Siti Salwa; Shamsuddin, Rosnah

2014-01-01

Okara, soybean waste from tofu and soymilk production, was utilised as a natural antioxidant in soap formulation for stratum corneum application. D-optimal mixture design was employed to investigate the influence of the main compositions of okara soap containing different fatty acid and oils (virgin coconut oil A (24–28% w/w), olive oil B (15–20% w/w), palm oil C (6–10% w/w), castor oil D (15–20% w/w), cocoa butter E (6–10% w/w), and okara F (2–7% w/w)) by saponification process on the response hardness of the soap. The experimental data were utilized to carry out analysis of variance (ANOVA) and to develop a polynomial regression model for okara soap hardness in terms of the six design factors considered in this study. Results revealed that the best mixture was the formulation that included 26.537% A, 19.999% B, 9.998% C, 16.241% D, 7.633% E, and 7.000% F. The results proved that the difference in the level of fatty acid and oils in the formulation significantly affects the hardness of soap. Depending on the desirable level of those six variables, creation of okara based soap with desirable properties better than those of commercial ones is possible. PMID:25548777

40 CFR 417.30 - Applicability; description of the soap manufacturing by fatty acid neutralization subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... manufacturing by fatty acid neutralization subcategory. 417.30 Section 417.30 Protection of Environment... POINT SOURCE CATEGORY Soap Manufacturing by Fatty Acid Neutralization Subcategory § 417.30 Applicability; description of the soap manufacturing by fatty acid neutralization subcategory. The provisions of this subpart...

Effects of polyalkylene glycols and fatty acid soaps on properties of synthetic lubricating-cooling fluids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stulii, A.A.

1983-01-01

The lack of any effect of the polyalkylene glycols on the series of properties of the fatty acid soaps was confirmed by replacing the PEG-35 in the synthetic lubricating-cooling fluid (LCF) by a polyethylene glycol with a molecular weight of 400 or 6000, a propylene oxide oligomer with a molecular weight of 700, or a copolymer of ethylene and propylene oxides (Pluronic 44, Pluriol PE-6400, Hydropol 200). Attempts to select surfactants and optimal concentrations in synthetic LCFs based on polyalkylene glycols. Indicates that of the studied soaps, those of the most interest are the triethanolamine soaps of individual C/sub 6/-C/submore » 10/ fatty acids and commercial mixed C/sub 7/-C/sub 9/ synthetic fatty acids. Finds that the polyalkylene glycols and the indicated soaps supplement each other, imparting the required set of properties to the LCF.« less

A Discovery Experiment: Carbon Dioxide Soap Bubble Dynamics.

ERIC Educational Resources Information Center

Millikan, Roger C.

1978-01-01

The observation of soap bubbles in a beaker of carbon dioxide gas helps students to feel the pleasure that comes from understanding nature, from applying that understanding to real problems, and from making unexpected discoveries that yield to analysis. (Author/BB)

Contamination of liquid soap for hospital use with Raoultella planticola.

PubMed

García-San Miguel, L; Sáez-Nieto, J A; Medina, M J; López Hernández, S; Sánchez-Romero, I; Ganga, B; Asensio, Á

2014-03-01

This article reports the contamination of a batch of liquid soap for hospital use with Raoultella planticola. The micro-organism was first identified as Klebsiella pneumoniae due to the inability of automated systems to characterize this species. There is a need to strengthen the inspection of cosmetic products to be used in the hospital setting. It is recommended that hospitalized patients at the highest risk of infection should use antimicrobial soaps for personal hygiene. The incidence of infections due to R. planticola is unknown as it is usually misclassified as Klebsiella spp. by automated systems. Copyright © 2014 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Performance of lead-free versus lead-based hunting ammunition in ballistic soap.

PubMed

Gremse, Felix; Krone, Oliver; Thamm, Mirko; Kiessling, Fabian; Tolba, René Hany; Rieger, Siegfried; Gremse, Carl

2014-01-01

Lead-free hunting bullets are an alternative to lead-containing bullets which cause health risks for humans and endangered scavenging raptors through lead ingestion. However, doubts concerning the effectiveness of lead-free hunting bullets hinder the wide-spread acceptance in the hunting and wildlife management community. We performed terminal ballistic experiments under standardized conditions with ballistic soap as surrogate for game animal tissue to characterize dimensionally stable, partially fragmenting, and deforming lead-free bullets and one commonly used lead-containing bullet. The permanent cavities created in soap blocks are used as a measure for the potential wound damage. The soap blocks were imaged using computed tomography to assess the volume and shape of the cavity and the number of fragments. Shots were performed at different impact speeds, covering a realistic shooting range. Using 3D image segmentation, cavity volume, metal fragment count, deflection angle, and depth of maximum damage were determined. Shots were repeated to investigate the reproducibility of ballistic soap experiments. All bullets showed an increasing cavity volume with increasing deposited energy. The dimensionally stable and fragmenting lead-free bullets achieved a constant conversion ratio while the deforming copper and lead-containing bullets showed a ratio, which increases linearly with the total deposited energy. The lead-containing bullet created hundreds of fragments and significantly more fragments than the lead-free bullets. The deflection angle was significantly higher for the dimensionally stable bullet due to its tumbling behavior and was similarly low for the other bullets. The deforming bullets achieved higher reproducibility than the fragmenting and dimensionally stable bullets. The deforming lead-free bullet closely resembled the deforming lead-containing bullet in terms of energy conversion, deflection angle, cavity shape, and reproducibility, showing that

The long-term use of soap does not affect the pH-maintenance mechanism of human skin.

PubMed

Takagi, Y; Kaneda, K; Miyaki, M; Matsuo, K; Kawada, H; Hosokawa, H

2015-05-01

The pH at the surface of healthy human skin is around 5. Cleansing the skin with soap increases the pH of the skin, which then returns to a more acidic pH within a few hours. However, the effects of skin cleansing with soap over a long time on the pH regulatory system is still unclear. We compared the pH of the skin between users of a soap-based cleanser and of a mild-acidic cleanser prior to and following the cleansing. This study had two groups of subjects, one group who had used a soap-based cleanser for more than 5 years and the other group who had used a mild-acidic cleanser for more than 5 years. The pH on the inner forearm of each subject was measured prior to and for 6 h after cleansing with a soap bar. There were no differences between the pH of the skin these two groups prior to cleansing, immediately after cleansing or in the pH recovery rate for 6 h. These results suggest that long-term continuous use of a soap-based cleanser does not affect the pH-maintaining mechanism of human skin. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Effects of soap-water wash on human epidermal penetration.

PubMed

Zhu, Hanjiang; Jung, Eui-Chang; Phuong, Christina; Hui, Xiaoying; Maibach, Howard

2016-08-01

Skin decontamination is a primary interventional method used to decrease dermal absorption of hazardous contaminants, including chemical warfare agents, pesticides and industrial pollutants. Soap and water wash, the most common and readily available decontamination system, may enhance percutaneous absorption through the "wash-in effect." To understand better the effect of soap-water wash on percutaneous penetration, and provide insight to improving skin decontamination methods, in vitro human epidermal penetration rates of four C(14) -labeled model chemicals (hydroquinone, clonidine, benzoic acid and paraoxon) were assayed using flow-through diffusion cells. Stratum corneum (SC) absorption rates of these chemicals at various hydration levels (0-295% of the dry SC weights) were determined and compared with the results of the epidermal penetration study to clarify the effect of SC hydration on skin permeability. Results showed accelerated penetration curves of benzoic acid and paraoxon after surface wash at 30 min postdosing. Thirty minutes after washing (60 min postdosing), penetration rates of hydroquinone and benzoic acid decreased due to reduced amounts of chemical on the skin surface and in the SC. At the end of the experiment (90 min postdosing), a soap-water wash resulted in lower hydroquinone penetration, greater paraoxon penetration and similar levels of benzoic acid and clonidine penetration compared to penetration levels in the non-wash groups. The observed wash-in effect agrees with the enhancement effect of SC hydration on the SC chemical absorption rate. These results suggest SC hydration derived from surface wash to be one cause of the wash-in effect. Further, the occurrence of a wash-in effect is dependent on chemical identity and elapsed time between exposure and onset of decontamination. By reducing chemical residue quantity on skin surface and in the SC reservoir, the soap-water wash may decrease the total quantity of chemical absorbed in the

Isolation of Raoultella planticola from refillable antimicrobial liquid soap dispensers in a dental setting

PubMed Central

Tomlin, Nancy; Ruby, John D.

2014-01-01

Background Liquid antimicrobial soaps are commonly used in the dental healthcare setting for hand washing to minimize the potential spread of infectious agents to healthcare workers (HCW) and patients. The purpose of the current study was to evaluate possible bacterial contamination of antimicrobial liquid soap dispensers located in two institutional comprehensive dental care clinics. Methods Fourteen soap dispensers and original stock containers were sampled. A 1 ml aliquot was diluted in 10 ml of phosphate buffer (Tween 80). Serial dilutions were plated in duplicate on neutralizing agar and incubated for 7 days. Molecular identification was performed using 500 bp comparisons of 16S rDNA sequencing. Taq PCR was performed with sequence specific primers for Raoultella species. Results Bacterial growth was observed at 18 hours for 57% (8/14) of soap dispenser samples. Bacterial densities ranged from 4 ×102–6 ×109 CFU/mL. Original commercial containers exhibited no growth. Isolates were identified as Raoultella (Klebsiella) planticola. Conclusions This is the first study indicating recovery of R. planticola from antimicrobial liquid soap dispensers. R. planticola is a recognized environmental opportunistic pathogen that potentially poses a health concern. Practical Implications These findings indicate compliance problems with infection prevention recommendations and support the CDC’s recommendation that dispensers should not be “topped off”. High bacterial loads of R. planticola are inconsistent with infection control practices and are a concern since transmission and possible infection to the HCW or the patient may occur. PMID:25819655

Comparison of virucidal activity of alcohol-based hand sanitizers versus antimicrobial hand soaps in vitro and in vivo.

PubMed

Steinmann, J; Paulmann, D; Becker, B; Bischoff, B; Steinmann, E; Steinmann, J

2012-12-01

Three ethanol-based sanitizers were compared with three antimicrobial liquid soaps for their efficacy to inactivate polio-, adeno-, vaccinia- and bovine viral diarrhoea virus (BVDV) as well as feline calicivirus (FCV) and murine norovirus (MNV) as surrogates for human norovirus in a suspension test. Additionally, sanitizers and soaps were examined against MNV in a modified fingerpad method. All sanitizers sufficiently inactivated the test viruses in the suspension test whereas two soaps were active only against vaccinia virus and BVDV. In the modified fingerpad test a povidone-iodine-containing soap was superior to the sanitizers whereas the other two soaps showed no activity. Copyright © 2012 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Do Aloe vera and Ageratum conyzoides enhance the anti-microbial activity of traditional medicinal soft soaps (Osedudu)?

PubMed

Moody, J O; Adebiyi, O A; Adeniyi, B A

2004-05-01

The Nigerian traditional soft soaps prepared using varied locally sourced raw materials such as cocoa pod ash (Theobroma cacao) palm kernel shaft ash (Elaies guineensis) have been evaluated for their physico-chemical properties and anti-microbial activities using standard pharmacopoeia protocols and an in-vitro agar diffusion bioassay method. The anti-microbial evaluation was done with and without incorporation of Aloe vera and Ageratum conyzoides extractives into the soap samples. Results showed that the physico-chemical properties of the soaps are dependent on the raw materials utilised. The incorporated medicinal plants used in this study, however, did not show any significant effect on the anti-microbial activities exhibited by the various soaps against the bacterial and fungal test organisms. Copyright 2004 Elsevier Ireland Ltd.

A miracle happening to a laser beam in a soap film

DOE Office of Scientific and Technical Information (OSTI.GOV)

Startsev, Aleksandr V; Stoilov, Yurii Yu

2003-05-31

When a 10 {mu}W - 3 W laser beam (for example, at 632.8 nm) is focused into a usual soap film of thickness between 10 nm and 10 {mu}m from the side or through a defect on the film surface, the self-channeling of the beam propagating in the film is observed. The beam also exhibits self-branching into submicron filaments, the so-called whiskers of length several tens of centimetres. The results of experiments on the dynamics of behaviour of these whiskers in a soap film, their polariton nature, and possible applications are discussed. (letters)

An Analysis of an Autoclitic Analogue in Pigeons

ERIC Educational Resources Information Center

Kuroda, Toshikazu; Lattal, Kennon A.; García-Penagos, Andrés

2014-01-01

Using a conditional discrimination procedure, pigeons were exposed to a nonverbal analogue of qualifying autoclitics such as "definitely" and "maybe." It has been suggested that these autoclitics are similar to tacts except that they are under the control of private discriminative stimuli. Instead of the conventional assumption…

Chemical Constituents and an Alternative Medicinal Veterinary Herbal Soap Made from Senna macranthera

PubMed Central

Inoue Andrade, Flávia; Purgato, Gislaine Aparecida; de Faria Maia, Thalita; Pais Siqueira, Raoni; Lima, Sâmia; Diaz, Marisa Alves Nogueira

2015-01-01

Upon undergoing biomonitoring, the most active dichloromethane extract retrieved from Senna macranthera roots led to the isolation of three main compounds: emodine, physione, and chrysophanol. In this sequence, these compounds revealed a potential antibacterial activity against Staphylococcus aureus strains isolated from animals with mastitis infections with minimum inhibitory concentration (MIC) values of 20, 90, and 90 μg mL−1, respectively. Therefore, an herbal soap was also produced from this same active extract. This soap was tested in vitro using gloves contaminated by animals with bovine mastitis that had been discarded after use by milkers and showed similar results to previously tested compounds. These results indicate the potential of this plant as an alternative veterinary medicine for the production of antibacterial soaps that aimed at controlling bovine mastitis infections in small Brazilian farms. PMID:25821480

Optimizing Libraries’ Content Findability Using Simple Object Access Protocol (SOAP) With Multi-Tier Architecture

NASA Astrophysics Data System (ADS)

Lahinta, A.; Haris, I.; Abdillah, T.

2017-03-01

The aim of this paper is to describe a developed application of Simple Object Access Protocol (SOAP) as a model for improving libraries’ digital content findability on the library web. The study applies XML text-based protocol tools in the collection of data about libraries’ visibility performance in the search results of the book. Model from the integrated Web Service Document Language (WSDL) and Universal Description, Discovery and Integration (UDDI) are applied to analyse SOAP as element within the system. The results showed that the developed application of SOAP with multi-tier architecture can help people simply access the website in the library server Gorontalo Province and support access to digital collections, subscription databases, and library catalogs in each library in Regency or City in Gorontalo Province.

Observation and simulation of flow on soap film induced by concentration gradient

NASA Astrophysics Data System (ADS)

Ohnishi, Mitsuru; Yoshihara, Shoichi; Azuma, Hisao

The behavior of the flow and capillary wave induced on the film surface by the surfactant concentration difference is studied. Flat soap film is used as a model of thin film. The result is applicable to the case of flow by thermal gradient. The Schlieren method is used to observe the flow and the wave on the soap film. It is found that the wave velocities, in the case of a high surface tension difference, are linearly related to the square root of the surface tension difference.

Effect of calcium soaps of fatty acids and administration of somatotropin on milk production, preovulatory follicular development, and plasma and follicular fluid lipid composition in high yielding dairy cows.

PubMed

Moallem, U; Folman, Y; Bor, A; Arav, A; Sklan, D

1999-11-01

The effect of fat and bovine somatotropin (bST) on preovulatory follicular hormones and lipids was evaluated by feeding cows for 150 d from parturition a control diet, a control diet plus 0.55 kg/d of calcium soaps of fatty acids, or a control diet with 500 mg of bST injected every 14 d. Fourteen days after a synchronized or natural estrus, cows were injected with a PGF2 alpha analogue; 48 h later, follicular fluid from all ovarian follicles > 8 mm was aspirated. Cows fed fat or injected with bST produced more milk and milk solids than did control cows, and cows on the bST treatment lost more body condition after calving than did cows on the other treatments. Both treatments changed the proportion of estradiol-active follicles (> 400 ng of estradiol/ml of follicular fluid) and the correlation between follicular fluid estradiol concentration and the total number large follicles per cow. In follicles aspirated between 60 and 90 DIM the percentage of estradiol-active follicles was 67, 40, and 0 for cows on the control, calcium soaps of fatty acids, and bST treatments, respectively. After 90 DIM, no differences existed between treatments in the percentage of estradiol-active follicles. Estradiol concentration in follicular fluid was correlated with DIM at follicle aspiration (r = 0.51). The proportion of oleic acid in free fatty acids in plasma at 50 DIM was lower in control cows and was lower in follicular fluid of estradiol-active follicles. Both calcium soaps of fatty acids and bST had a considerable effect on follicular development and activity and the composition of fatty acids in follicles.

Modeling drop impacts on inclined flowing soap films

NASA Astrophysics Data System (ADS)

Basu, Saikat; Yawar, Ali; Concha, Andres; Bandi, Mahesh

2015-11-01

Small drops impinging on soap films flowing at an angle primarily exhibit three fundamental regimes of post-impact dynamics: (a) the drop bounces off the film surface, (b) it coalesces with the downstream flow, and (c) it pierces through the film. During impact, the drop deforms along with a simultaneous, almost elastic deformation of the film transverse to the stream direction. Hence, the governing dynamics for this interaction present the rare opportunity to explore the in-tandem effects of elasticity and hydrodynamics alike. In this talk, we outline the analytical framework to study the drop impact dynamics. The model assumes a deformable drop and a deformable three-dimensional soap film and invokes a parametric study to qualify the three mentioned impact types. The physical parameters include the impact angle, drop impact speed, and the diameters of the drop prior to and during impact when it deforms and spreads out. Our model system offers a path towards optimization of interactions between a spray and a flowing liquid.

The elasticity of soap bubbles containing wormlike micelles.

PubMed

Sabadini, Edvaldo; Ungarato, Rafael F S; Miranda, Paulo B

2014-01-28

Slow-motion imaging of the rupture of soap bubbles generally shows the edges of liquid films retracting at a constant speed (known as the Taylor-Culick velocity). Here we investigate soap bubbles formed from simple solutions of a cationic surfactant (cetyltrimethylammonium bromide - CTAB) and sodium salicylate. The interaction of salicylate ions with CTAB leads to the formation of wormlike micelles (WLM), which yield a viscoelastic behavior to the liquid film of the bubble. We demonstrate that these elastic bubbles collapse at a velocity up to 30 times higher than the Taylor-Culick limit, which has never been surpassed. This is because during the bubble inflation, the entangled WLM chains stretch, storing elastic energy. This extra energy is then released during the rupture of the bubble, yielding an additional driving force for film retraction (besides surface tension). This new mechanism for the bursting of elastic bubbles may have important implications to the breakup of viscoelastic sprays in industrial applications.

Use of Electronic Loggers to Measure Changes in the Rates of Hand Washing with Soap in Low-Income Urban Households in India

PubMed Central

Wright, Richard L.; Zillmer, Ruediger; Biran, Adam; Hall, Peter; Sidibe, Myriam

2015-01-01

We evaluated the utility of electronic loggers to measure the effects of a simple intervention designed to influence the rates of hand washing with soap within enclosed toilets and bathrooms in low-income urban households in Kerala, India. 58 households were given three items with embedded electronic loggers for a period of 2-5 days. Two logged soaps tracked hand and body washing in the bathroom. The third logged item was a water vessel used for flushing the toilet and for post-defecation anal cleansing; this served as a marker of toilet use. In addition, 28 households in a Soap by toilet arm were given an additional logged soap, to be kept by the toilet, and used for hand washing. Compared with the Soap in bathroom arm, the loggers in the Soap by toilet households recorded 73% greater daily use of soaps designated for hand washing (t(36)=2.92, p<0.01) and 172% greater use within 2 minutes of the use of the water vessel (t(36)=3.51, p = 0.001). We conclude that the loggers were capable of detecting changes in the rates of hand washing with soap and changes in hand washing with soap after use of the toilet. Further adoption of logger technologies would enable more insightful studies of hand washing within urban environments. PMID:26101886

Use of Electronic Loggers to Measure Changes in the Rates of Hand Washing with Soap in Low-Income Urban Households in India.

PubMed

Wright, Richard L; Zillmer, Ruediger; Biran, Adam; Hall, Peter; Sidibe, Myriam

2015-01-01

We evaluated the utility of electronic loggers to measure the effects of a simple intervention designed to influence the rates of hand washing with soap within enclosed toilets and bathrooms in low-income urban households in Kerala, India. 58 households were given three items with embedded electronic loggers for a period of 2-5 days. Two logged soaps tracked hand and body washing in the bathroom. The third logged item was a water vessel used for flushing the toilet and for post-defecation anal cleansing; this served as a marker of toilet use. In addition, 28 households in a Soap by toilet arm were given an additional logged soap, to be kept by the toilet, and used for hand washing. Compared with the Soap in bathroom arm, the loggers in the Soap by toilet households recorded 73% greater daily use of soaps designated for hand washing (t(36)=2.92, p<0.01) and 172% greater use within 2 minutes of the use of the water vessel (t(36)=3.51, p = 0.001). We conclude that the loggers were capable of detecting changes in the rates of hand washing with soap and changes in hand washing with soap after use of the toilet. Further adoption of logger technologies would enable more insightful studies of hand washing within urban environments.

Formulation of Antibacterial Liquid Soap from Nyamplung Seed Oil (Calophyllum inophyllum L) with Addition of Curcuma heyneana and its Activity Test on Staphylococcus aureus

NASA Astrophysics Data System (ADS)

Widyaningsih, S.; Chasani, M.; Diastuti, H.; Novayanti

2018-04-01

The increasing demand of soap encourages new innovations of it’s quantity, quality, benefits and raw materials. One of the innovations that has been developed is the use of nyamplung (C. inophyllum L) seed oil as basic ingredients of soap, with addition of active substances such as antibacterial and fragrance. This research aims to determine best formulation of liquid soap according to SNI 06-4085-1996 and its antibacterial activity after addition of n-hexane fraction of C. heyneana rhizome and fragrance from lavender flower oil at various concentrations, then a hedonic test was conducted to evaluate the panelist's preference towards the soap with the best formulation. This research has been done through several stages of soap making with saponification method, soap characterization according to SNI 06-4085-1996, determination of best formulation of liquid soap based on the effectiveness index method and antibacterial activity test of liquid soap to S.aureus with disc diffusion method and hedonic test using some parameters such as colour, odor, foam, clean power and effects after being used. The results showed that the best characteristic soap according to SNI 06-4085-1996 was soap with 0.2% antibacterial content and 2.5% perfume. The best soap characteristic showed total fatty acid 67.49%, free fatty acid 1.01%, neutral fat 7.24%, weight of type 1.05 g/mL, pH of 9.85 and foam stability 76.69%. The results of the antibacterial activity test of the best formula soap showed the inhibitory zone of 14.92 mm.

Hand hygiene with soap and water is superior to alcohol rub and antiseptic wipes for removal of Clostridium difficile.

PubMed

Oughton, Matthew T; Loo, Vivian G; Dendukuri, Nandini; Fenn, Susan; Libman, Michael D

2009-10-01

To evaluate common hand hygiene methods for efficacy in removing Clostridium difficile. Randomized crossover comparison among 10 volunteers with hands experimentally contaminated by nontoxigenic C. difficile. Interventions included warm water with plain soap, cold water with plain soap, warm water with antibacterial soap, antiseptic hand wipes, alcohol-based handrub, and a control involving no intervention. All interventions were evaluated for mean reduction in colony-forming units (CFUs) under 2 contamination protocols: "whole hand" and "palmar surface." Results were analyzed according to a Bayesian approach, by using hierarchical models adjusted for multiple observations. Under the whole-hand protocol, the greatest adjusted mean reductions were achieved by warm water with plain soap (2.14 log(10) CFU/mL [95% credible interval (CrI), 1.74-2.54 log(10) CFU/mL]), cold water with plain soap (1.88 log(10) CFU/mL [95% CrI, 1.48-2.28 log(10) CFU/mL), and warm water with antibacterial soap (1.51 log(10) CFU/mL [95% CrI, 1.12-1.91 log(10) CFU/mL]), followed by antiseptic hand wipes (0.57 log(10) CFU/mL [95% CrI, 0.17-0.96 log(10) CFU/mL]). Alcohol-based handrub (0.06 log(10) CFU/mL [95% CrI, -0.34 to 0.45 log(10) CFU/mL]) was equivalent to no intervention. Under the palmar surface protocol, warm water with plain soap, cold water with plain soap, and warm water with antibacterial soap again yielded the greatest mean reductions, followed by antiseptic hand wipes (26.6, 26.6, 26.6, and 21.9 CFUs per plate, respectively), when compared with alcohol-based handrub. Hypothenar (odds ratio, 10.98 [95% CrI, 1.96-37.65]) and thenar (odds ratio, 6.99 [95% CrI, 1.25-23.41]) surfaces were more likely than fingertips to remain heavily contaminated after handwashing. Handwashing with soap and water showed the greatest efficacy in removing C. difficile and should be performed preferentially over the use of alcohol-based handrubs when contact with C. difficile is suspected or likely.

Measurement of contact-line dissipation in a nanometer-thin soap film

NASA Astrophysics Data System (ADS)

Guo, Shuo; Lee, Chun Huen; Sheng, Ping; Tong, Penger

2015-01-01

We report a direct measurement of the friction coefficient ξc of two fluctuating contact lines formed on a fiber surface when a long glass fiber intersects the two water-air interfaces of a thin soap film. The glass fiber of diameter d in the range of 0.4-4 μ m and length 100-300 μ m is glued onto the front end of a rectangular cantilever used for atomic force microscopy. As a sensitive mechanical resonator, the hanging fiber probe can accurately measure a minute change of its viscous damping caused by the soap film. By measuring the broadening of the resonant peak of the hanging fiber probe with varying viscosity η of the soap film and different surface treatments of the glass fiber, we confirm that the contact line dissipation obeys a universal scaling law, ξc=α π d η , where the coefficient α =1.1 ±0.3 is insensitive to the change of liquid-solid contact angle. The experimental result is in good agreement with the numerical result based on the phase field model under the generalized Navier boundary conditions.

Measurement of contact-line dissipation in a nanometer-thin soap film.

PubMed

Guo, Shuo; Lee, Chun Huen; Sheng, Ping; Tong, Penger

2015-01-01

We report a direct measurement of the friction coefficient ξ(c) of two fluctuating contact lines formed on a fiber surface when a long glass fiber intersects the two water-air interfaces of a thin soap film. The glass fiber of diameter d in the range of 0.4-4 μm and length 100-300 μm is glued onto the front end of a rectangular cantilever used for atomic force microscopy. As a sensitive mechanical resonator, the hanging fiber probe can accurately measure a minute change of its viscous damping caused by the soap film. By measuring the broadening of the resonant peak of the hanging fiber probe with varying viscosity η of the soap film and different surface treatments of the glass fiber, we confirm that the contact line dissipation obeys a universal scaling law, ξ(c)=απdη, where the coefficient α=1.1±0.3 is insensitive to the change of liquid-solid contact angle. The experimental result is in good agreement with the numerical result based on the phase field model under the generalized Navier boundary conditions.

Performance of Lead-Free versus Lead-Based Hunting Ammunition in Ballistic Soap

PubMed Central

Gremse, Felix; Krone, Oliver; Thamm, Mirko; Kiessling, Fabian; Tolba, René Hany; Rieger, Siegfried; Gremse, Carl

2014-01-01

Background Lead-free hunting bullets are an alternative to lead-containing bullets which cause health risks for humans and endangered scavenging raptors through lead ingestion. However, doubts concerning the effectiveness of lead-free hunting bullets hinder the wide-spread acceptance in the hunting and wildlife management community. Methods We performed terminal ballistic experiments under standardized conditions with ballistic soap as surrogate for game animal tissue to characterize dimensionally stable, partially fragmenting, and deforming lead-free bullets and one commonly used lead-containing bullet. The permanent cavities created in soap blocks are used as a measure for the potential wound damage. The soap blocks were imaged using computed tomography to assess the volume and shape of the cavity and the number of fragments. Shots were performed at different impact speeds, covering a realistic shooting range. Using 3D image segmentation, cavity volume, metal fragment count, deflection angle, and depth of maximum damage were determined. Shots were repeated to investigate the reproducibility of ballistic soap experiments. Results All bullets showed an increasing cavity volume with increasing deposited energy. The dimensionally stable and fragmenting lead-free bullets achieved a constant conversion ratio while the deforming copper and lead-containing bullets showed a ratio, which increases linearly with the total deposited energy. The lead-containing bullet created hundreds of fragments and significantly more fragments than the lead-free bullets. The deflection angle was significantly higher for the dimensionally stable bullet due to its tumbling behavior and was similarly low for the other bullets. The deforming bullets achieved higher reproducibility than the fragmenting and dimensionally stable bullets. Conclusion The deforming lead-free bullet closely resembled the deforming lead-containing bullet in terms of energy conversion, deflection angle, cavity shape

FT-IR spectra of the anti-HIV nucleoside analogue d4T (Stavudine). Solid state simulation by DFT methods and scaling by different procedures

NASA Astrophysics Data System (ADS)

Alcolea Palafox, M.; Kattan, D.; Afseth, N. K.

2018-04-01

A theoretical and experimental vibrational study of the anti-HIV d4T (stavudine or Zerit) nucleoside analogue was carried out. The predicted spectra in the three most stable conformers in the biological active anti-form of the isolated state were compared. Comparison of the conformers with those of the natural nucleoside thymidine was carried out. The calculated spectra were scaled by using different scaling procedures and three DFT methods. The TLSE procedure leads to the lowest error and is thus recommended for scaling. With the population of these conformers the IR gas-phase spectra were predicted. The crystal unit cell of the different polymorphism forms of d4T were simulated through dimer forms by using DFT methods. The scaled spectra of these dimer forms were compared. The FT-IR spectrum was recorded in the solid state in the 400-4000 cm-1 range. The respective vibrational bands were analyzed and assigned to different normal modes of vibration by comparison with the scaled vibrational values of the different dimer forms. Through this comparison, the polymorphous form of the solid state sample was identified. The study indicates that d4T exist only in the ketonic form in the solid state. The results obtained were in agreement with those determined in related anti-HIV nucleoside analogues.

New test method for the evaluation of the preservation efficacy of soaps at very alkaline pH made by saponification.

PubMed

Témoin-Fardini, S; Servant, J; Sellam, S

2017-10-01

The aim of this study was to develop a test method to evaluate the preservation efficacy for a specific product, a very high-alkaline liquid soap (pH around 10) made by a saponification process. Several manufacturers have experienced contamination issues with these high-pH soaps despite passing a classic preservative efficacy challenge test or even a multi-inoculation challenge test. Bacteria were isolated from contaminated soaps and were identified using 16S rRNA gene sequencing. High-alkaline-pH unpreserved soaps were tested using the Thor Personal Care internal multichallenge test method (TM206) with classical microorganisms and then with the bacterial strains isolated from various contaminated soaps (TM768). Preservatives were added to these soaps and assessed for their efficacy using the newly developed test. Four different species of bacteria (Nesterenkonia lacusekhoensis, Dermacoccus sp., Halomonas sp. and Roseomonas sp.) were identified by sequencing among the contaminants of the various soaps tested. Among these, only one bacterial species, Nesterenkonia lacusekhoensis, appeared to be responsible for the specific contamination of these high-alkaline soaps. Thus, one specific wild-type strain of Nesterenkonia lacusekhoensis, named as strain 768, was used in a new multi-inoculation test (TM768). Unlike the single inoculation challenge test, the multi-inoculation test using the Nesterenkonia strain 768 was able to predict the sensitivity of a product towards this bacterium. Among the 27 different preservatives tested, 10 were able to protect the formula against contamination with this bacterium. This study enabled the development of a test method to evaluate the efficacy of preservation using a specific bacterium, Nesterenkonia lacusekhoensis, responsible for the contamination of very alkaline soaps made by saponification and identify an appropriate preservative system. © 2017 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

Wire Frame Holds Water-Soap Film in Space

NASA Technical Reports Server (NTRS)

2003-01-01

Expedition 6 astronaut Dr. Don Pettit photographed a cube shaped wire frame supporting a thin film made from a water-soap solution during his Saturday Morning Science aboard the International Space Station's (ISS) Destiny Laboratory. Food coloring was added to several faces to observe the effects of diffusion within the film.

Soap film vibration: origin of the dissipation.

PubMed

Acharige, Sébastien Kosgodagan; Elias, Florence; Derec, Caroline

2014-11-07

We investigate the complex dispersion relationship of a transverse antisymmetric wave on a horizontal soap film. Experimentally, the complex wave number k at a fixed forcing frequency is determined by measuring the vibrating amplitude of the soap film: the wavelength (linked to the real part of k) is determined by the spatial variation of the amplitude; the decay length (linked to the imaginary part of k) is determined by analyzing the resonance curves of the vibrating wave as a function of frequency. Theoretically, we compute the complex dispersion relationship taking into account the physical properties of the bulk liquid and gas phase, and of the gas-liquid interfaces. The comparison between the computation (developed to the leading order under our experimental conditions) and the experimental results confirms that the phase velocity is fixed by the interplay between surface tension, and liquid and air inertia, as reported in previous studies. Moreover, we show that the attenuation of the transverse antisymmetric wave originates from the viscous dissipation in the gas phase surrounding the liquid film. This result is an important step in understanding the propagation of an acoustic wave in liquid foam, using a bottom-up approach.

From R&D to end users applications in operational oceanography: The navy's "SOAP" case study

NASA Astrophysics Data System (ADS)

Giraud Saint-Albin, S.; Jourdan, D.

2003-04-01

For the last ten years, the CMO/BRESM has conducted an operational program for Ocean Analysis and Prediction SOAP, whose goal has been to support sea activities with high resolution mesoscale ocean nowcast products. Successive prototypes have been generated, operated and improved in tandem with a continuous re-evaluation of Navy Needs. This strategy played a key-role in defining the concept of “real-time integrated oceanography” which relies on remote and in situ ocean observations, (a hierarchy of) ocean models and data assimilation methods. The paper focuses on the results of the latter feasability study for next SOAP prototype: the military motivation for developing new prototypes is to extend the application domain of SOAP operational products from the operative (~ a description of the synoptic scale) to the tactical ( ~ a tailored product to strategic needs) relevance. Current SOAP P2 system is as a transition system pulled by end-user’s requirements and designed by research oceanographers from existing tools and models. The development of SOAP P3 has just started and will benefit from the emergence of an increasing offer of ocean modelling results, pushed by the GODAE initiative. It will be based on MERCATOR high resolution prototypes. From that starting point future developments will have to address both issues of defense specific requirements for high resolution ocean modeling and computation of relevant acoustical products for military applications. Especially, the crucial needs for assessing the end-users’ products reliability should be explored.

Isolation of Raoultella planticola from refillable antimicrobial liquid soap dispensers in a dental setting.

PubMed

Momeni, Stephanie S; Tomlin, Nancy; Ruby, John D

2015-04-01

Liquid antimicrobial soaps are commonly used in the dental health care setting for hand washing to minimize the potential spread of infectious agents to health care workers and patients. The purpose of the current study was to evaluate possible bacterial contamination of antimicrobial liquid soap dispensers located in 2 institutional comprehensive dental care clinics. Fourteen soap dispensers and 16 original stock containers were sampled. A 1-milliliter aliquot was diluted in 10 mL of phosphate buffer (Tween-80; Acros). Serial dilutions were plated in duplicate on neutralizing agar and incubated for 7 days. Molecular identification was performed using 500 base pair comparisons of 16S ribosomal ribonucleic acid sequencing. Taq polymerase chain reaction was performed with sequence-specific primers for Raoultella species. Bacterial growth was observed at 18 hours for 57% (8 of 14) of soap dispenser samples. Bacterial densities ranged from 4 × 10(2) to 6 × 10(9) colony-forming units per milliliter. Original commercial containers exhibited no growth. Isolates were identified as Raoultella (Klebsiella) planticola. This is the first study to the authors' knowledge indicating recovery of R. planticola from antimicrobial liquid soap dispensers. R. planticola is a recognized environmental opportunistic pathogen that potentially poses a health concern. These findings indicate compliance problems with infection prevention recommendations and support the US Centers for Disease Control and Prevention's recommendation that dispensers should not be topped off. High bacterial loads of R. planticola are inconsistent with infection control practices and are a concern because transmission and possible infection to the health care worker or the patient may occur. Copyright © 2015 American Dental Association. Published by Elsevier Inc. All rights reserved.

SOAP 2.0: Spot Oscillation And Planet 2.0

NASA Astrophysics Data System (ADS)

Dumusque, Xavier; Boisse, I.; Santos, N. C.

2015-04-01

SOAP (Spot Oscillation And Planet) 2.0 simulates the effects of dark spots and bright plages on the surface of a rotating star, computing their expected radial velocity and photometric signatures. It includes the convective blueshift and its inhibition in active regions.

Small-Body Extensions for the Satellite Orbit Analysis Program (SOAP)

NASA Technical Reports Server (NTRS)

Carnright, Robert; Stodden, David; Coggi, John

2008-01-01

An extension to the SOAP software allows users to work with tri-axial ellipsoid-based representations of planetary bodies, primarily for working with small, natural satellites, asteroids, and comets. SOAP is a widely used tool for the visualization and analysis of space missions. The small body extension provides the same visualization and analysis constructs for use with small bodies. These constructs allow the user to characterize satellite path and instrument cover information for small bodies in both 3D display and numerical output formats. Tri-axial ellipsoids are geometric shapes the diameters of which are different in each of three principal x, y, and z dimensions. This construct provides a better approximation than using spheres or oblate spheroids (ellipsoids comprising two common equatorial diameters as a distinct polar diameter). However, the tri-axial ellipsoid is considerably more difficult to work with from a modeling perspective. In addition, the SOAP small-body extensions allow the user to actually employ a plate model for highly irregular surfaces. Both tri-axial ellipsoids and plate models can be assigned to coordinate frames, thus allowing for the modeling of arbitrary changes to body orientation. A variety of features have been extended to support tri-axial ellipsoids, including the computation and display of the spacecraft sub-orbital point, ground trace, instrument footprints, and swathes. Displays of 3D instrument volumes can be shown interacting with the ellipsoids. Longitude/latitude grids, contour plots, and texture maps can be displayed on the ellipsoids using a variety of projections. The distance along an arbitrary line of sight can be computed between the spacecraft and the ellipsoid, and the coordinates of that intersection can be plotted as a function of time. The small-body extension supports the same visual and analytical constructs that are supported for spheres and oblate spheroids in SOAP making the implementation of the more

Ultra-pure soft water ameliorates atopic skin disease by preventing metallic soap deposition in NC/Tnd mice and reduces skin dryness in humans.

PubMed

Tanaka, Akane; Matsuda, Akira; Jung, Kyungsook; Jang, Hyosun; Ahn, Ginnae; Ishizaka, Saori; Amagai, Yosuke; Oida, Kumiko; Arkwright, Peter D; Matsuda, Hiroshi

2015-09-01

Mineral ions in tap water react with fatty acids in soap, leading to the formation of insoluble precipitate (metallic soap) on skin during washing. We hypothesised that metallic soap might negatively alter skin conditions. Application of metallic soap onto the skin of NC/Tnd mice with allergic dermatitis further induced inflammation with elevation of plasma immunoglobulin E and proinflammatory cytokine expression. Pruritus and dryness were ameliorated when the back of mice was washed with soap in Ca2+- and Mg2+-free ultra-pure soft water (UPSW). Washing in UPSW, but not tap water, also protected the skin of healthy volunteers from the soap deposition. Furthermore, 4 weeks of showering with UPSW reduced dryness and pruritus of human subjects with dry skin. Washing with UPSW may be therapeutically beneficial in patients with skin troubles.

5. FOURTH FLOOR, HOTEL SOAP LINES TO NORTHWEST: PRESS (LEFT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. FOURTH FLOOR, HOTEL SOAP LINES TO NORTHWEST: PRESS (LEFT CENTER), MANUAL CUTTERS (CENTER, RIGHT CENTER) - Colgate & Company Jersey City Plant, Building No. B-15, 90-96 Greene Street, Jersey City, Hudson County, NJ

Boundary singularities produced by the motion of soap films.

PubMed

Goldstein, Raymond E; McTavish, James; Moffatt, H Keith; Pesci, Adriana I

2014-06-10

Recent work has shown that a Möbius strip soap film rendered unstable by deforming its frame changes topology to that of a disk through a "neck-pinching" boundary singularity. This behavior is unlike that of the catenoid, which transitions to two disks through a bulk singularity. It is not yet understood whether the type of singularity is generally a consequence of the surface topology, nor how this dependence could arise from an equation of motion for the surface. To address these questions we investigate experimentally, computationally, and theoretically the route to singularities of soap films with different topologies, including a family of punctured Klein bottles. We show that the location of singularities (bulk or boundary) may depend on the path of the boundary deformation. In the unstable regime the driving force for soap-film motion is the mean curvature. Thus, the narrowest part of the neck, associated with the shortest nontrivial closed geodesic of the surface, has the highest curvature and is the fastest moving. Just before onset of the instability there exists on the stable surface the shortest closed geodesic, which is the initial condition for evolution of the neck's geodesics, all of which have the same topological relationship to the frame. We make the plausible conjectures that if the initial geodesic is linked to the boundary, then the singularity will occur at the boundary, whereas if the two are unlinked initially, then the singularity will occur in the bulk. Numerical study of mean curvature flows and experiments support these conjectures.

Boundary singularities produced by the motion of soap films

PubMed Central

Goldstein, Raymond E.; McTavish, James; Moffatt, H. Keith; Pesci, Adriana I.

2014-01-01

Recent work has shown that a Möbius strip soap film rendered unstable by deforming its frame changes topology to that of a disk through a “neck-pinching” boundary singularity. This behavior is unlike that of the catenoid, which transitions to two disks through a bulk singularity. It is not yet understood whether the type of singularity is generally a consequence of the surface topology, nor how this dependence could arise from an equation of motion for the surface. To address these questions we investigate experimentally, computationally, and theoretically the route to singularities of soap films with different topologies, including a family of punctured Klein bottles. We show that the location of singularities (bulk or boundary) may depend on the path of the boundary deformation. In the unstable regime the driving force for soap-film motion is the mean curvature. Thus, the narrowest part of the neck, associated with the shortest nontrivial closed geodesic of the surface, has the highest curvature and is the fastest moving. Just before onset of the instability there exists on the stable surface the shortest closed geodesic, which is the initial condition for evolution of the neck’s geodesics, all of which have the same topological relationship to the frame. We make the plausible conjectures that if the initial geodesic is linked to the boundary, then the singularity will occur at the boundary, whereas if the two are unlinked initially, then the singularity will occur in the bulk. Numerical study of mean curvature flows and experiments support these conjectures. PMID:24843162

Soap Operas and Captioning in the EFL Class.

ERIC Educational Resources Information Center

Huffman, Donald T.

A teacher describes the use of closed-caption decoding of television melodramas to teach English as a second language (ESL). The approach uses evening soap operas that afford a range of English usage and accents, realistic dialogue, entertainment, and coverage of current social issues and are closed-captioned for the hearing-impaired. The programs…

Soap-film flow induced by electric fields in asymmetric frames.

PubMed

Mollaei, S; Nasiri, M; Soltanmohammadi, N; Shirsavar, R; Ramos, A; Amjadi, A

2018-04-01

Net fluid flow of soap films induced by (ac or dc) electric fields in asymmetric frames is presented. Previous experiments of controllable soap film flow required the simultaneous use of an electrical current passing through the film and an external electric field or the use of nonuniform ac electric fields. Here a single voltage difference generates both the electrical current going through the film and the electric field that actuates on the charge induced on the film. The film is set into global motion due to the broken symmetry that appears by the use of asymmetric frames. If symmetric frames are used, the film flow is not steady but time dependent and irregular. Finally, we study numerically these film flows by employing the model of charge induction in ohmic liquids.

Soap-film flow induced by electric fields in asymmetric frames

NASA Astrophysics Data System (ADS)

Mollaei, S.; Nasiri, M.; Soltanmohammadi, N.; Shirsavar, R.; Ramos, A.; Amjadi, A.

2018-04-01

Net fluid flow of soap films induced by (ac or dc) electric fields in asymmetric frames is presented. Previous experiments of controllable soap film flow required the simultaneous use of an electrical current passing through the film and an external electric field or the use of nonuniform ac electric fields. Here a single voltage difference generates both the electrical current going through the film and the electric field that actuates on the charge induced on the film. The film is set into global motion due to the broken symmetry that appears by the use of asymmetric frames. If symmetric frames are used, the film flow is not steady but time dependent and irregular. Finally, we study numerically these film flows by employing the model of charge induction in ohmic liquids.

The Utilization of VCO (Virgin Coconut Oil) in Manufacturing of Solid Soap with Red Betel Leaf Extract Addition (Paper Crotum Ruiz &Pav)

NASA Astrophysics Data System (ADS)

Sari, M.

2018-04-01

Soap is a compound of sodium or potassium with fatty acids from vegetable oils or solid animal fats, soft or liquid, and foamy. Considering the potential of VCO as the raw material for making soap and supported by the benefits of red betel leaves, then this research is done by making solid bath soap from VCO which is supplemented with Red betel leaf extract. The purpose of this research is to make solid soap from VCO with an extract of red betel leaf based on SNINo.06-3532199. Analyzing VCO oil, which is used for the manufacture of soap, consists of analysis of saponification figures, Iodine number and peroxide number. Has made solid soap from VCO oil with Red betel leaf extract. From the five quality standards established under SNI 06-3532-1994 only two quality standards that can be done that is water quality and the amount of acidity. The percent of water quality obtained is 10% meanwhile the amount of acidity obtained is 9,32%. According to the data, it can be concluded that the solid soap made was not fulfill SNI 06-3532-1994.

Lead(ii) soaps: crystal structures, polymorphism, and solid and liquid mesophases.

PubMed

Martínez-Casado, F J; Ramos-Riesco, M; Rodríguez-Cheda, J A; Redondo-Yélamos, M I; Garrido, L; Fernández-Martínez, A; García-Barriocanal, J; da Silva, I; Durán-Olivencia, M; Poulain, A

2017-07-05

The long-chain members of the lead(ii) alkanoate series or soaps, from octanoate to octadecanoate, have been thoroughly characterized by means of XRD, PDF analysis, DSC, FTIR, ssNMR and other techniques, in all their phases and mesophases. The crystal structures at room temperature of all of the members of the series are now solved, showing the existence of two polymorphic forms in the room temperature crystal phase, different to short and long-chain members. Only nonanoate and decanoate present both forms, and this polymorphism is proven to be monotropic. At higher temperature, these compounds present a solid mesophase, defined as rotator, a liquid crystal phase and a liquid phase, all of which have a similar local arrangement. Since some lead(ii) soaps appear as degradation compounds in oil paintings, the solved crystal structures of lead(ii) soaps can now be used as fingerprints for their detection using X-ray diffraction. Pair distribution function analysis on these compounds is very similar in the same phases and mesophases for the different members, showing the same short range order. This observation suggests that this technique could also be used in the detection of these compounds in disordered phases or in the initial stages of formation in paintings.

Soaps and germicides as adjunct topical antimycotic agents on candida species implicated in vulvovaginal candidasis.

PubMed

Ogunshe, Adenike A O; Omotoso, Oluwatoyin A; Akindele, Titilayo M

2011-06-01

The study aims at evaluating the potentials of soaps and germicides/disinfectants as adjunct topical anti-vulvovaginal candidasis agents. In vitro inhibitory activities of the test agents, prepared according to the manufacturer's specification for toilet and midwifery purposes were determined using modified agar well-diffusion method. Varied susceptibility patterns were exhibited by Candida albicans (26.5%), C. glabrata (18.4%), C. pseudotropicalis (14.3%) and C. tropicalis (40.8%) implicated in vulvovaginal candidasis, indicating Crusader oil (100%), Meriko (95%), Tetmosol (84.7%) and Aloe (68.4%) as the most inhibitory soaps against the Candida strains. The in vitro inhibitory activities of the germicides and disinfectants ranged between (Dettol; 34.6% and Purit; 84.6%) for C. albicans; (Roberts; 33.3% and Purit; 83.3%) for C. glabrata; (Roberts; 21.4% and Purit; 92.9%) for C. pseudotropicalis; (Dettol; 35.0% and Purit; 87.5%) for C. tropicalis respectively. All the Candida strains were totally inhibited by the germicides and disinfectants at the second lower dilutions, except in Morigad towards C. albicans (69.2%]) C. glabrata (72.2%), C. pseudotropicalis (92.9%) and C. tropicalis (82.5%) but none of the vaginal Lactobacillus strains was inhibited by the soaps, germicides or disinfectant. About 90% of a control group indicated relief after pubic cleansing with soaps, germicides and disinfectants. Results indicatied the safety of soaps, germicides and disinfectants as potential adjunct topical cleansing-agents in cases of vaginal itching and candidasis, a common mucosal infection caused by opportunistic yeasts of the Candida genus.

Environmental monitoring study of linear alkylbenzene sulfonates and insoluble soap in Spanish sewage sludge samples.

PubMed

Cantarero, Samuel; Zafra-Gómez, Alberto; Ballesteros, Oscar; Navalón, Alberto; Reis, Marco S; Saraiva, Pedro M; Vílchez, José L

2011-01-01

In this work we present a monitoring study of linear alkylbenzene sulfonates (LAS) and insoluble soap performed on Spanish sewage sludge samples. This work focuses on finding statistical relations between LAS concentrations and insoluble soap in sewage sludge samples and variables related to wastewater treatment plants such as water hardness, population and treatment type. It is worth to mention that 38 samples, collected from different Spanish regions, were studied. The statistical tool we used was Principal Component Analysis (PC), in order to reduce the number of response variables. The analysis of variance (ANOVA) test and a non-parametric test such as the Kruskal-Wallis test were also studied through the estimation of the p-value (probability of obtaining a test statistic at least as extreme as the one that was actually observed, assuming that the null hypothesis is true) in order to study possible relations between the concentration of both analytes and the rest of variables. We also compared LAS and insoluble soap behaviors. In addition, the results obtained for LAS (mean value) were compared with the limit value proposed by the future Directive entitled "Working Document on Sludge". According to the results, the mean obtained for soap and LAS was 26.49 g kg(-1) and 6.15 g kg(-1) respectively. It is worth noting that LAS mean was significantly higher than the limit value (2.6 g kg(-1)). In addition, LAS and soap concentrations depend largely on water hardness. However, only LAS concentration depends on treatment type.

Thermal Convection in Two-Dimensional Soap Films

NASA Astrophysics Data System (ADS)

Zhang, Jie; Wu, X. L.

2002-11-01

Thermal convection in a fluid is a common phenomenon. Due to thermal expansion, the light warm fluid at the bottom tends to rise and the cold, heavier fluid at the top tends to fall. This so-called thermal convection exists in earth atmosphere and in oceans. It is also an important mechanism by which energy is transported in stars. In this study we investigate thermal convection in a vertical soap film.

Toxicity of insecticidal soaps to the Asian citrus psyllid (Diaphorina citri) and two of its natural enemies

USDA-ARS?s Scientific Manuscript database

Insecticidal soaps (hereafter “soaps”) are labeled for use by homeowners and also can be used in citrus grown for the organic market. Soaps control some insect pests and therefore might be an alternative to conventional pesticides for control of the Asian citrus psyllid, Diaphorina citri Kuwayama (...

7. FOURTH FLOOR, DETAIL OF HOTEL SOAP LINE TO WEST: ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. FOURTH FLOOR, DETAIL OF HOTEL SOAP LINE TO WEST: FERGUSON & HAAS AUTOMATIC WRAPPING MACHINE INSTALLED BY 1929 - Colgate & Company Jersey City Plant, Building No. B-15, 90-96 Greene Street, Jersey City, Hudson County, NJ

Efficacy of triclosan as an antimicrobial hand soap and its potential impact on antimicrobial resistance: a focused review.

PubMed

Giuliano, Christopher A; Rybak, Michael J

2015-03-01

Triclosan is a synthetic biocide found in many household products, including antimicrobial hand soap. Levels of triclosan have been found throughout the environment and in human urine, blood, and even breast milk. Increasing levels of exposure to triclosan have led to concerns over the development of resistance to triclosan and cross-resistance to other antimicrobials. We performed a literature search to assess whether the widespread use of triclosan displays a favorable benefit: risk ratio, defined by evaluation of triclosan's efficacy as an antimicrobial hand soap and its potential effect on the development of antimicrobial resistance. Data from laboratory-based studies regarding the efficacy of triclosan are conflicting, although well-designed studies suggest no significant difference in efficacy over nonantimicrobial soap. In addition, when triclosan was introduced in a community setting, no beneficial effects were observed on the reduction of infections over nonantimicrobial soap. Resistance to triclosan and cross-resistance to antimicrobials have been consistently demonstrated in laboratory settings, although overall resistance rates and cross-resistance rates in the community setting are low. Based on the available evidence, the risk of potential antimicrobial resistance outweighs the benefit of widespread triclosan use in antimicrobial soaps. © 2015 Pharmacotherapy Publications, Inc.

Observed practices and perceived advantages of different hand cleansing agents in rural Bangladesh: ash, soil, and soap.

PubMed

Nizame, Fosiul A; Nasreen, Sharifa; Halder, Amal K; Arman, Shaila; Winch, Peter J; Unicomb, Leanne; Luby, Stephen P

2015-06-01

Bangladeshi communities have historically used ash and soil as handwashing agents. A structured observation study and qualitative interviews on the use of ash/soil and soap as handwashing agents were conducted in rural Bangladesh to help develop a handwashing promotion intervention. The observations were conducted among 1,000 randomly selected households from 36 districts. Fieldworkers observed people using ash/soil to wash their hand(s) on 13% of occasions after defecation and on 10% after cleaning a child's anus. This compares with 19% of people who used soap after defecation and 27% after cleaning a child who defecated. Using ash/soil or soap was rarely (< 1%) observed at other times recommended for handwashing. The qualitative study enrolled 24 households from three observation villages, where high usage of ash/soil for handwashing was detected. Most informants reported that ash/soil was used only for handwashing after fecal contact, and that ash/soil could clean hands as effectively as soap. © The American Society of Tropical Medicine and Hygiene.

Method of refining cracked oil by using metallic soaps. [desulfurization of cracked oils

DOE Office of Scientific and Technical Information (OSTI.GOV)

Masakichi, M.; Marunouchi, K.K.; Yoshimura, T.

1937-04-13

The method of refining cracked oil consists in dissolving oil-soluble heavy metallic soap of oleic acid in a volatile organic solvent which will disperse homogeneously in cracked oil; pouring the solution thus obtained slowly into cracked oil to effect dispersion naturally and homogeneously at room temperature in the cracked oil. This process serves to react the mercaptans in the cracked oil with the heavy metallic soap by a double decomposition reaction and to precipitate the mercaptans as insoluble metallic salts. The remaining liquid is distilled to separate it from the remaining solvent.

4. THIRD FLOOR CENTER BAY TO NORTH; SOAP KETTLES TO ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. THIRD FLOOR CENTER BAY TO NORTH; SOAP KETTLES TO LEFT AND RIGHT, TWO-STORY TANK AT CENTER REAR - Colgate & Company Jersey City Plant, Building No. B-13, 48-50 Grand Street, Jersey City, Hudson County, NJ

Analysis of a deflating soap bubble

NASA Astrophysics Data System (ADS)

Jackson, David P.; Sleyman, Sarah

2010-10-01

A soap bubble on the end of a cylindrical tube is seen to deflate as the higher pressure air inside the bubble escapes through a tube. We perform an experiment to measure the radius of the slowly deflating bubble and observe that the radius decreases to a minimum before quickly increasing. This behavior reflects the fact that the bubble ends up as a flat surface over the end of the tube. A theoretical analysis reproduces this behavior and compares favorably with the experimental data.

NASA/ESMD Analogue Mission Plans

NASA Technical Reports Server (NTRS)

Hoffman, Stephen J.

2007-01-01

A viewgraph presentation exploring Earth and its analogues is shown. The topics include: 1) ESMD Goals for the Use of Earth Analogues; 2) Stakeholders Summary; 3) Issues with Current Analogue Situation; 4) Current state of Analogues; 5) External Implementation Plan (Second Step); 6) Recent Progress in Utilizing Analogues; 7) Website Layout Example-Home Page; 8) Website Layout Example-Analogue Site; 9) Website Layout Example-Analogue Mission; 10) Objectives of ARDIG Analog Initiatives; 11) Future Plans; 12) Example: Cold-Trap Sample Return; 13) Example: Site Characterization Matrix; 14) Integrated Analogue Studies-Prerequisites for Human Exploration; and 15) Rating Scale Definitions.

Psychosocial Factors Mediating the Effect of the CHoBI7 Intervention on Handwashing With Soap: A Randomized Controlled Trial.

PubMed

George, Christine Marie; Biswas, Shwapon; Jung, Danielle; Perin, Jamie; Parvin, Tahmina; Monira, Shirajum; Saif-Ur-Rahman, K M; Rashid, Mahamud-Ur; Bhuyian, Sazzadul Islam; Thomas, Elizabeth D; Dreibelbis, Robert; Begum, Farzana; Zohura, Fatema; Zhang, Xiaotong; Sack, David A; Alam, Munirul; Sack, R Bradley; Leontsini, Elli; Winch, Peter J

2017-08-01

Inadequate hand hygiene is estimated to result in nearly 300,000 deaths annually, with the majority of deaths being among children younger than 5 years. In an effort to promote handwashing with soap and water treatment behaviors among highly susceptible household members of cholera patients, we recently developed the Cholera-Hospital-Based Intervention-for-7-Days (CHoBI7); chobi means picture in Bengali. This 1-week handwashing with soap and water treatment intervention is delivered by a promoter in the hospital and the home to cholera patients and their household members. In our randomized controlled trial of this intervention, we observed a significant reduction in symptomatic cholera infections during the 1-week intervention period compared to the control arm and sustained high uptake of observed handwashing with soap behaviors up to 12 months postintervention. The aim of the present study was to assess the underlying mechanism of change that led to the high handwashing with soap behavior observed among participants who received the CHoBI7 intervention. Handwashing with soap was measured using 5-hour structured observation, and psychosocial factors were assessed using a structured questionnaire among 170 intervention and 174 control household members enrolled in the CHoBI7 trial. To investigate potential mediators of the CHoBI7 intervention effect, mediation models were performed. Response efficacy was found to mediate the intervention's effect on habit formation for handwashing with soap at the 1-week follow-up, and disgust, convenience, and cholera awareness were mediators of habit maintenance at the 6- to 12-month follow-up. These results support the use of theory-driven approaches for the development and implementation of handwashing with soap interventions.

The efficacy of Pistacia Terebinthus soap in the treatment of cetuximab-induced skin toxicity.

PubMed

Tastekin, Didem; Tambas, Makbule; Kilic, Kemal; Erturk, Kayhan; Arslan, Deniz

2014-12-01

This open-labeled phase II, efficacy-finding study evaluated the efficiency and safety of Pistacia terebinthus soap in metastatic colorectal cancer patients who developed cetuximab induced skin toxicity. Patients who received cetuximab plus chemotherapy and developed Grade 2 or 3 skin toxicity were treated twice daily with a soap made of oil extracted from Pistacia terebinthus. During treatment, no topical or oral antibiotics, corticosteroids or other moisturizers were used. Patients were examined 1 week later and their photographs were taken. Fifteen mCRC patients who developed skin toxicity while receiving first-line CTX in combination with chemotherapy were included into the study. Eight patients were male and the median age was 58 (25-70). Sixty percent of the patients (n:9) had Grade 3 skin toxicity. Complete response rates in patients with Grade 2 and Grade 3 skin toxicities were 100 and 33%, respectively. In the remaining patients with Grade 3 toxicity the skin toxicity regressed to Grade 1. The objective response rate was 100%, and no delay, dose reduction or discontinuation of CTX treatment due to skin toxicity was necessary. Skin toxicity reoccurred in all patients when patients stopped administering the soap and therefore they used it throughout the cetuximab treatment. Pistacia terebinthus soap seemed to be used safely and effectively in the treatment of skin toxicity induced by Cetuximab.

MANCHESTER MILLS, PRINT WORKS: BLUE DYE AND SOAPING; PRINTING AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

MANCHESTER MILLS, PRINT WORKS: BLUE DYE AND SOAPING; PRINTING AND BLEACHING BUILDINGS. PHOTOCOPY OF c. 1905 VIEW LOOKING NORTHEAST. From the collection of Mr. George Durette, Photographer, Manchester, N. H. - Amoskeag Millyard, Canal Street, Manchester, Hillsborough County, NH

Removal of Escherichia coli and Enterococcus faecalis after Hand Washing with Antimicrobial and Nonantimicrobial Soap and Persistence of These Bacteria in Rinsates.

PubMed

Pérez-Garza, J; García, S; Heredia, N

2017-10-01

Food handlers are important sources of contamination in the agricultural environment. This study was conducted (i) to evaluate the activity of antimicrobial soaps against Escherichia coli and Enterococcus faecalis using a hand washing model with soiled hands and (ii) to determine the survival and persistence of these bacteria in rinsates. Sterilized agricultural soil from tomato and pepper farms was inoculated with E. coli or E. faecalis at 10 3 or 10 6 CFU/g. Decontaminated hands were placed in contact with contaminated soil for 2 min and were then washed with soaps with or without antimicrobial compounds (citric extracts, chloroxylenol, triclosan, or chlorhexidine gluconate). As the control, hands were washed with sterile distilled water. The levels of bacteria remaining on the hands and recovered from the rinsates were determined using a membrane filtration method and selective media. Antimicrobial soaps removed levels of E. coli similar to those removed by distilled water and nonantimicrobial soap on hands contaminated with E. coli at 10 3 CFU/g. However, when hands were contaminated with E. coli at 10 6 CFU/g, more E. coli was removed with the chlorhexidine gluconate soap. When hands were contaminated with E. faecalis at 10 3 CFU/g, bacteria were removed more effectively with soaps containing chloroxylenol or chlorhexidine gluconate. When hands were contaminated with E. faecalis at 10 6 CFU/g, all of the antimicrobial soaps were more effective for removing the bacteria than were distilled water and nonantimicrobial soap. E. coli grew in all of the hand washing rinsates except that containing triclosan, whereas E. faecalis from the 10 6 CFU/g treatments grew in rinsates containing chlorhexidine gluconate and in the distilled water rinsates. Washing with antimicrobial soap was more effective for reducing bacteria on soiled hands than was washing with water or nonantimicrobial soap. However, persistence or growth of bacteria in these rinsates poses health risks.

The Manufacture, Properties, and Testing of Napalm Soaps

DTIC Science & Technology

1943-11-17

prrcltio’n. Tests at 1000C. a.nd 100 p.s,,i. %Inhibitor Induction Addod Pcriod, mins. N one 0 20 Eydroquinone 1 5 duPont #19 1 150 Lecithin 1 SF0 1 45...acetone tends to hydrolyze the soap, liberating more free acid which in turn is removed by the solvent. Table XXIV shows results obtained with a

Monitoring the thinning dynamics of soap films by phase shift interferometry. The case of perfluoropolyether surfactants.

PubMed

Gambi, Cecilia M C; Vannoni, Maurizio; Sordini, Andrea; Molesini, Giuseppe

2014-02-01

An interferometric method to monitor the thinning process of vertical soap films from a water solution of surfactant materials is reported. Raw data maps of optical path difference introduced by the film are obtained by conventional phase shift interferometry. Off-line re-processing of such raw data taking into account the layered structure of soap films leads to an accurate measurement of the geometrical thickness. As an example of data acquisition and processing, the measuring chain is demonstrated on perfluoropolyether surfactants; the section profile of vertical films is monitored from drawing to black film state, and quantitative data on the dynamics of the thinning process are presented. The interferometric method proves effective to the task, and lends itself to further investigate the physical properties of soap films.

The effect of a soap promotion and hygiene education campaign on handwashing behaviour in rural India: a cluster randomised trial.

PubMed

Biran, Adam; Schmidt, Wolf-Peter; Wright, Richard; Jones, Therese; Seshadri, M; Isaac, Pradeep; Nathan, N A; Hall, Peter; McKenna, Joeleen; Granger, Stewart; Bidinger, Pat; Curtis, Val

2009-10-01

To investigate the effectiveness of a hygiene promotion intervention based on germ awareness in increasing handwashing with soap on key occasions (after faecal contact and before eating) in rural Indian households. Cluster randomised trial of a hygiene promotion intervention in five intervention and five control villages. Handwashing was assessed through structured observation in a random sample of 30 households per village. Additionally, soap use was monitored in a sub-sample of 10 households per village using electronic motion detectors embedded in soap bars. The intervention reached 40% of the target population. Germ awareness increased as well as reported handwashing (a possible indicator of perceived social norms). Observed handwashing with soap on key occasions was rare (6%), especially after faecal contact (2%). Observed handwashing with soap on key occasions did not change 4 weeks after the intervention in either the intervention arm (-1%, 95% CI -2%/+0.3%), or the control arm (+0.4%, 95% CI -1%/+2%). Data from motion detectors indicated a significant but small increase in overall soap use in the intervention arm. We cannot confidently identify the nature of this increase except to say that there was no change in a key measure of handwashing after defecation. The intervention proved scalable and effective in raising hygiene awareness. There was some evidence of an impact on soap use but not on the primary outcome of handwashing at key times. However, the results do not exclude that changes in knowledge and social norms may lay the foundations for behaviour change in the longer term.

Calcium soap from palm fatty acid distillate for ruminant feed: The influence of water temperature

NASA Astrophysics Data System (ADS)

Handojo, Lienda A.; Indarto, Antonius; Shofinita, Dian; Meitha, Anggina; Nabila, Rakhmawati; Triharyogi, Harry; Kevin, Leonardus

2018-03-01

As the largest palm oil producing country in the world, Indonesia also produces abundant amount of Palm Fatty Acid Distillate (PFAD), a by-product of Crude Palm Oil (CPO) refining process. PFAD can be utilized as the raw material for calcium soap, ruminant feed that is widely used to increase milk yield, as well as to increase the ruminant’s fertility. However, the practice of feeding ruminants with calcium soap has not been practiced in Indonesia, which makes it imperative to develop calcium soap production process from PFAD within the country. This research aimed to study the effect of operating conditions of the saponification reaction using PFAD and CaO as reactants on the quality of the calcium soap obtained. The saponification reaction was carried out by modified fusion method. A range of stoichiometric mole ratios of CaO to PFAD (1.0 to 1.6) and the temperature of water (60-90°C) were studied in this research. An increase in the stoichiometric mole ratio of CaO/PFAD was observed to cause a decrease in the acid value, which indicates an increase in the reaction conversion. In contrast, the temperature of water was found to have little impact on the acid value of the product.

12. DETAIL OF REMOVED PLODDER (UPPER HALF) FROM HOTEL SOAP ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. DETAIL OF REMOVED PLODDER (UPPER HALF) FROM HOTEL SOAP LINE No. 6 STORED IN G BLOCK (HAER No. NJ-71-NN) - Colgate & Company Jersey City Plant, Building No. B-14, 54-58 Grand Street, Jersey City, Hudson County, NJ

13. DETAIL OF REMOVED PLODDER (LOWER HALF) FROM HOTEL SOAP ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. DETAIL OF REMOVED PLODDER (LOWER HALF) FROM HOTEL SOAP LINE No. 6 STORED IN G BLOCK (HAER No. NJ-71-NN) - Colgate & Company Jersey City Plant, Building No. B-14, 54-58 Grand Street, Jersey City, Hudson County, NJ

SOAP-V: Introducing a method to empower medical students to be change agents in bending the cost curve.

PubMed

Moser, Eileen M; Huang, Grace C; Packer, Clifford D; Glod, Susan; Smith, Cynthia D; Alguire, Patrick C; Fazio, Sara B

2016-03-01

Medical students must learn how to practice high-value, cost-conscious care. By modifying the traditional SOAP (Subjective-Objective-Assessment-Plan) presentation to include a discussion of value (SOAP-V), we developed a cognitive forcing function designed to promote discussion of high-value, cost-conscious care during patient delivery. The SOAP-V model prompts the student to consider (1) the evidence that supports a test or treatment, (2) the patient's preferences and values, and (3) the financial cost of a test or treatment compared to alternatives. Students report their findings to their teams during patient care rounds. This tool has been successfully used at 3 medical schools. Preliminary results find that students who have been trained in SOAP-V feel more empowered to address the economic healthcare crisis, are more comfortable in initiating discussions about value, and are more likely to consider potential costs to the healthcare system. © 2015 Society of Hospital Medicine.

Draft Genome Sequences of Klebsiella oxytoca Isolates Originating from a Highly Contaminated Liquid Hand Soap Product.

PubMed

Hammerl, J A; Lasch, P; Nitsche, A; Dabrowski, P W; Hahmann, H; Wicke, A; Kleta, S; Al Dahouk, S; Dieckmann, R

2015-07-23

In 2013, contaminated liquid soap was detected by routine microbiological monitoring of consumer products through state health authorities. Because of its high load of Klebsiella oxytoca, the liquid soap was notified via the European Union Rapid Alert System for Dangerous Non-Food Products (EU-RAPEX) and recalled. Here, we present two draft genome sequences and a summary of their general features. Copyright © 2015 Hammerl et al.

Mercury and hydroquinone content of skin toning creams and cosmetic soaps, and the potential risks to the health of Ghanaian women.

PubMed

Agorku, Eric Selorm; Kwaansa-Ansah, Edward Ebow; Voegborlo, Ray Bright; Amegbletor, Pamela; Opoku, Francis

2016-01-01

In this study, sixty-two (62) skin-lightening creams and soaps were analysed for total mercury and hydroquinone levels. Total mercury was determined by the Cold Vapour Atomic Absorption Spectrophotometry using an automatic mercury analyser and hydroquinone by High Performance Liquid Chromatography. The mean concentration of total mercury in skin toning creams and cosmetic soaps were 0.098 ± 0.082 and 0.152 ± 0.126 μg/g, respectively. The mean concentration of hydroquinone was 0.243 ± 0.385 and 0.035 ± 0.021 % in skin toning creams and cosmetic soaps, respectively. All the creams and soaps analysed had mercury and hydroquinone levels below the US Food and Drug Administration's acceptable limit of 1 μg/g and 2 %, respectively. The low levels of mercury and hydroquinone in the creams and soaps analysed in this study therefore do not pose any potential risk to consumers who are mostly women in Ghana.

Evaluating Sustainability: Soap versus Biodiesel Production from Plant Oils

ERIC Educational Resources Information Center

Pohl, Nicola L. B.; Streff, Jennifer M.; Brokman, Steve

2012-01-01

Herein we describe a series of experiments for the undergraduate organic laboratory curriculum in which various plant oils (soybean, rapeseed, and olive) are subjected to saponification and transesterification reactions to create a set of compounds that can function as soaps or as fuels. The experiments introduce students to and asks them to…

Collapse of the soap-film bridge - Quasistatic description

NASA Astrophysics Data System (ADS)

Cryer, Steven A.; Steen, Paul H.

1992-11-01

Observations of the collapse of a soap-film bridge from a connected to a disconnected state are recorded. The equilibrium framework for this nonequilibrium event is classical. Experiments confirm predictions of stable and unstable equilibria. A quasistatic description is introduced for the dynamic states to extend the static theory. It is found to adequately describe the collapse trajectory while the bridge is still connected.

Collapse of the soap-film bridge - Quasistatic description

NASA Technical Reports Server (NTRS)

Cryer, Steven A.; Steen, Paul H.

1992-01-01

Observations of the collapse of a soap-film bridge from a connected to a disconnected state are recorded. The equilibrium framework for this nonequilibrium event is classical. Experiments confirm predictions of stable and unstable equilibria. A quasistatic description is introduced for the dynamic states to extend the static theory. It is found to adequately describe the collapse trajectory while the bridge is still connected.

Observed Handwashing with Soap Practices Among Cholera Patients and Accompanying Household Members in a Hospital Setting (CHoBI7 Trial).

PubMed

Zohura, Fatema; Bhuyian, Sazzadul Islam; Monira, Shirajum; Begum, Farzana; Biswas, Shwapon K; Parvin, Tahmina; Sack, David; Sack, R Bradley; Leontsini, Elli; Saif-Ur-Rahman, K M; Rashid, Mahamud-Ur; Sharmin, Rumana; Zhang, Xiaotong; Alam, Munirul; George, Christine Marie

2016-12-07

Household members of cholera patients are at a 100 times higher risk of cholera than the general population. Despite this risk, there are only a handful of studies that have investigated the handwashing practices among hospitalized diarrhea patients and their accompanying household members. To investigate handwashing practices in a hospital setting among this high-risk population, 444 hours of structured observation was conducted in a hospital in Dhaka, Bangladesh, among 148 cholera patients and their household members. Handwashing with soap practices were observed at the following key events: after toileting, after cleaning the anus of a child, after removing child feces, during food preparation, before eating, and before feeding. Spot-checks were also conducted to observe the presence of soap at bathroom areas. Overall, 4% (4/103) of key events involved handwashing with soap among cholera patients and household members during the structured observation period. This was 3% (1/37) among cholera patients and 5% (3/66) for household members. For toileting events, observed handwashing with soap was 7% (3/46) overall, 7% (1/14) for cholera patients, and 6% (2/32) for household members. For food-related events, overall observed handwashing with soap was 2% (2/93 overall), and 0% (0/34) and 3% (2/59) for cholera patients and household members, respectively. Soap was observed at only 7% (4/55) of handwashing stations used by patients and household members during spot-checks. Observed handwashing with soap at key times among patients and accompanying household members was very low. These findings highlight the urgent need for interventions to target this high-risk population. © The American Society of Tropical Medicine and Hygiene.

On the nature of laser polariton tracks in soap films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Startsev, Aleksandr V; Stoilov, Yurii Yu

2004-06-30

The results of the study of narrow laser tracks in soap films with the divergence below the diffraction-limited value are presented, and the mechanism of formation of narrow channels (spatial polariton solitons) based on laser dielectrophoresis in films is proposed. (nonlinear optical phenomena)

Visualization of Sound Waves Using Regularly Spaced Soap Films

ERIC Educational Resources Information Center

Elias, F.; Hutzler, S.; Ferreira, M. S.

2007-01-01

We describe a novel demonstration experiment for the visualization and measurement of standing sound waves in a tube. The tube is filled with equally spaced soap films whose thickness varies in response to the amplitude of the sound wave. The thickness variations are made visible based on optical interference. The distance between two antinodes is…

Is Structured Observation a Valid Technique to Measure Handwashing Behavior? Use of Acceleration Sensors Embedded in Soap to Assess Reactivity to Structured Observation

PubMed Central

Ram, Pavani K.; Halder, Amal K.; Granger, Stewart P.; Jones, Therese; Hall, Peter; Hitchcock, David; Wright, Richard; Nygren, Benjamin; Islam, M. Sirajul; Molyneaux, John W.; Luby, Stephen P.

2010-01-01

Structured observation is often used to evaluate handwashing behavior. We assessed reactivity to structured observation in rural Bangladesh by distributing soap containing acceleration sensors and performing structured observation 4 days later. Sensors recorded the number of times soap was moved. In 45 participating households, the median number of sensor soap movements during the 5-hour time block on pre-observation days was 3.7 (range 0.3–10.6). During the structured observation, the median number of sensor soap movements was 5.0 (range 0–18.0), a 35% increase, P = 0.0004. Compared with the same 5-hour time block on pre-observation days, the number of sensor soap movements increased during structured observation by ≥ 20% in 62% of households, and by ≥ 100% in 22% of households. The increase in sensor soap movements during structured observation, compared with pre-observation days, indicates substantial reactivity to the presence of the observer. These findings call into question the validity of structured observation for measurement of handwashing behavior. PMID:21036840

Is structured observation a valid technique to measure handwashing behavior? Use of acceleration sensors embedded in soap to assess reactivity to structured observation.

PubMed

Ram, Pavani K; Halder, Amal K; Granger, Stewart P; Jones, Therese; Hall, Peter; Hitchcock, David; Wright, Richard; Nygren, Benjamin; Islam, M Sirajul; Molyneaux, John W; Luby, Stephen P

2010-11-01

Structured observation is often used to evaluate handwashing behavior. We assessed reactivity to structured observation in rural Bangladesh by distributing soap containing acceleration sensors and performing structured observation 4 days later. Sensors recorded the number of times soap was moved. In 45 participating households, the median number of sensor soap movements during the 5-hour time block on pre-observation days was 3.7 (range 0.3-10.6). During the structured observation, the median number of sensor soap movements was 5.0 (range 0-18.0), a 35% increase, P = 0.0004. Compared with the same 5-hour time block on pre-observation days, the number of sensor soap movements increased during structured observation by ≥ 20% in 62% of households, and by ≥ 100% in 22% of households. The increase in sensor soap movements during structured observation, compared with pre-observation days, indicates substantial reactivity to the presence of the observer. These findings call into question the validity of structured observation for measurement of handwashing behavior.

SOAP in Practice: Learning Outcomes of a Cross-Institutional Innovation Project Conducted by Teachers, Student Teachers, and Teacher Educators

ERIC Educational Resources Information Center

Seezink, Audrey; Poell, Rob; Kirschner, Paul

2010-01-01

This paper reports on a case study investigating learning outcomes at the individual and organisational level of a cross-institutional innovation project based on the SOAP approach. SOAP integrates "S"chooling of teachers, "O"rganisational development of schools, "A"ction- and development-oriented research, and…

Soap films and GeoGebra in the study of Fermat and Steiner points

NASA Astrophysics Data System (ADS)

Flores, Alfinio; Park, Jungeun

2018-05-01

We discuss how mathematics and secondary mathematics education majors developed an understanding of Fermat points for the triangle as well as Steiner points for the square and regular pentagon, and also of soap film configurations between parallel plates where forces are in equilibrium. The activities included the use of soap films and the interactive geometry program GeoGebra. Students worked in small groups using these tools to investigate the properties of Fermat and Steiner points and then justified the results of their investigations using geometrical arguments. These activities are specific approaches of how to encourage prospective teachers to use physical experiments to support students' development of mathematical curiosity and mathematical justifications.

Mapping of the Marangoni effect in soap films using Young's double-slit experiment

NASA Astrophysics Data System (ADS)

Emile, Janine; Emile, Olivier

2013-10-01

We report on the thickness variation measurement of a soap film due to a local perturbation, using Young's double-slit experiment configuration. We map a laser-heated deformation of a vertical free-standing draining thin soap film using the differential change of optical path in the interferometer. The experiment has a resolution of about 0.1 nm and enables to follow the liquid flow dynamics. We evidence a bottleneck formation in the heated region of the film that perturbs the usual flow. Such an experimental set-up could then be adapted to measure other tiny variations in fluctuating hydrodynamics such as capillary waves for example.

Effect of face washing with soap and water and cleaning with antiseptics on upper-lid bacteria of surgical eye patients.

PubMed

Bekibele, Charles O; Kehinde, Aderemi O; Ajayi, Benedictus G K

2010-12-01

To determine the effect of face washing with soap and water and cleaning with povidone iodine and cetrimide/chlorhexidine gluconate (Savlon) on upper-lid bacteria. Prospective, nonrandomized clinical trial. Eighty patients attending the Eye Clinic, University College Hospital, Ibadan, Nigeria. Eighty patients assigned to 4 groups had swabs of the upper eyelid skin taken before and after face wash with soap and water, and cleansing with Savlon and 5% povidone iodine. Specimens were cultured and Gram stained. Bacterial counts were carried out using standard techniques. Face washing with soap and water increased the proportion of patients with bacterial isolates from 80.0% to 87.5%. The average colony count increased from 187.1 to 318.5 colony units per mL (p = 0.02). Application of 5% povidone iodine without face washing with soap and water reduced the proportion of patients with bacterial isolates from 82.6% (mean count 196.5) to 28.6% (mean count 34.1)(p = 0.001); in comparison, the application of 5% povidone iodine after face washing with soap and water reduced the proportion from 71.4% (mean count 133.9) to 40.0% (mean count 69.0)(p = 0.01). Application of Savlon without face washing with soap and water reduced the proportion of patients with bacterial isolates from 100% (mean count 310.9) to 41.2% (mean count 19.8)(p = 0.004) compared with the application after face washing, which reduced the proportion from 89.5% (mean count 240.3) to 41.2% (mean count 82.9)(p = 0.02). Both povidone and Savlon are effective in reducing periocular bacteria in an African setting. Prior face washing with soap and water had no added benefit in reducing bacterial colony count.

Guide to resource conservation and cost savings opportunities in the soap, detergents and related products sector

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-10-01

This guide was prepared to help those involved in the manufacturing of soap, detergent, and related products to identify potential process improvements that will reduce production costs and conserve resources. The guide offers a series of generic process descriptions and checklists of improvement opportunities specific to each of five major processes used in the industry: Soap production, surfactant production, solid cake product formulation, liquid product formulation, and granulated powdered product formulation. The checklists identify thermal, electrical, environmental, water use, and low- or no-cost measures that can be implemented, as well as retrofit technology options. A variety of new technologies thatmore » may exhibit future potential are also described. Appendices include a glossary, background information on the Ontario soap/detergent industry, and description of the four major categories of ingredients used in the industry.« less

A free-flowing soap film combined with cavity ring-down spectroscopy as a detection system for liquid chromatography.

PubMed

Vogelsang, Markus; Welsch, Thomas; Jones, Harold

2010-05-07

We have shown that a free-flowing soap film has sufficiently high-quality optical properties to allow it to be used in the cavity of a ring-down spectrometer (CRDS). The flow rates required to maintain a stable soap film were similar to those used in liquid chromatography and thus allowed interfacing with an HPLC system for use as an optical detector. We have investigated the properties of the system in a relevant analytical application. The soap film/CRDS combination was used at 355 nm as a detector for the separation of a mixture of nitroarenes. These compounds play a role in the residue analysis of areas contaminated with explosives and their decomposition products. In spite of the short absorption path length (9 microm) obtained by the soap film, the high-sensitivity of CRDS allowed a limit of detection of 4 x 10(-6) in absorption units (AU) or less than 17 fmol in the detection volume to be achieved. Copyright (c) 2009 Elsevier B.V. All rights reserved.

6. 5TH FLOOR, VIEW NORTH OF KETTLE SOAP STORAGE TANKS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. 5TH FLOOR, VIEW NORTH OF KETTLE SOAP STORAGE TANKS (RIGHT) AND WEIGH HOPPERS OVER SITES OF REMOVED AMALGAMATORS (LEFT) - Colgate & Company Jersey City Plant, Building No. B-14, 54-58 Grand Street, Jersey City, Hudson County, NJ

Surface tension profiles in vertical soap films

NASA Astrophysics Data System (ADS)

Adami, N.; Caps, H.

2015-01-01

Surface tension profiles in vertical soap films are experimentally investigated. Measurements are performed by introducing deformable elastic objets in the films. The shape adopted by those objects once set in the film is related to the surface tension value at a given vertical position by numerically solving the adapted elasticity equations. We show that the observed dependency of the surface tension versus the vertical position is predicted by simple modeling that takes into account the mechanical equilibrium of the films coupled to previous thickness measurements.

SOAP 2.0: a tool to estimate the photometric and radial velocity variations induced by stellar spots and plages

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dumusque, X.; Boisse, I.; Santos, N. C., E-mail: xdumusque@cfa.harvard.edu

2014-12-01

This paper presents SOAP 2.0, a new version of the Spot Oscillation And Planet (SOAP) code that estimates in a simple way the photometric and radial velocity (RV) variations induced by active regions. The inhibition of the convective blueshift (CB) inside active regions is considered, as well as the limb brightening effect of plages, a quadratic limb darkening law, and a realistic spot and plage contrast ratio. SOAP 2.0 shows that the activity-induced variation of plages is dominated by the inhibition of the CB effect. For spots, this effect becomes significant only for slow rotators. In addition, in the casemore » of a major active region dominating the activity-induced signal, the ratio between the FWHM and the RV peak-to-peak amplitudes of the cross correlation function can be used to infer the type of active region responsible for the signal for stars with v sin i ≤8 km s{sup –1}. A ratio smaller than three implies a spot, while a larger ratio implies a plage. Using the observation of HD 189733, we show that SOAP 2.0 manages to reproduce the activity variation as well as previous simulations when a spot is dominating the activity-induced variation. In addition, SOAP 2.0 also reproduces the activity variation induced by a plage on the slowly rotating star α Cen B, which is not possible using previous simulations. Following these results, SOAP 2.0 can be used to estimate the signal induced by spots and plages, but also to correct for it when a major active region is dominating the RV variation.« less

Trehalose Analogues: Latest Insights in Properties and Biocatalytic Production

PubMed Central

Walmagh, Maarten; Zhao, Renfei; Desmet, Tom

2015-01-01

Trehalose (α-d-glucopyranosyl α-d-glucopyranoside) is a non-reducing sugar with unique stabilizing properties due to its symmetrical, low energy structure consisting of two 1,1-anomerically bound glucose moieties. Many applications of this beneficial sugar have been reported in the novel food (nutricals), medical, pharmaceutical and cosmetic industries. Trehalose analogues, like lactotrehalose (α-d-glucopyranosyl α-d-galactopyranoside) or galactotrehalose (α-d-galactopyranosyl α-d-galactopyranoside), offer similar benefits as trehalose, but show additional features such as prebiotic or low-calorie sweetener due to their resistance against hydrolysis during digestion. Unfortunately, large-scale chemical production processes for trehalose analogues are not readily available at the moment due to the lack of efficient synthesis methods. Most of the procedures reported in literature suffer from low yields, elevated costs and are far from environmentally friendly. “Greener” alternatives found in the biocatalysis field, including galactosidases, trehalose phosphorylases and TreT-type trehalose synthases are suggested as primary candidates for trehalose analogue production instead. Significant progress has been made in the last decade to turn these into highly efficient biocatalysts and to broaden the variety of useful donor and acceptor sugars. In this review, we aim to provide an overview of the latest insights and future perspectives in trehalose analogue chemistry, applications and production pathways with emphasis on biocatalysis. PMID:26084050

Fluid instabilities and wakes in a soap-film tunnel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vorobieff, P.; Ecke, R.E.

1999-05-01

We present a compact, low-budget two-dimensional hydrodynamic flow visualization system based on a tilted, gravity-driven soap film tunnel. This system is suitable for demonstrations and studies of a variety of fluid mechanics problems, including turbulent wakes past bluff bodies and lifting surfaces, Kelvin{endash}Helmholtz instability, and grid turbulence. {copyright} {ital 1999 American Association of Physics Teachers.}

A renaissance of soaps? - How to make clear and stable solutions at neutral pH and room temperature.

PubMed

Wolfrum, Stefan; Marcus, Julien; Touraud, Didier; Kunz, Werner

2016-10-01

Soaps are the oldest and perhaps most natural surfactants. However, they lost much of their importance since "technical surfactants", usually based on sulfates or sulfonates, have been developed over the last fifty years. Indeed, soaps are pH- and salt-sensitive and they are irritant, especially to the eyes. In food emulsions, although authorized, they have a bad taste, and long-chain saturated soaps have a high Krafft temperature. We believe that most or perhaps all of these problems can be solved with modern formulation approaches. We start this paper with a short overview of our present knowledge of soaps and soap formulations. Then we focus on the problem of the lacking soap solubility at neutral pH values. For example, it is well known that with the food emulsifier sodium oleate (NaOl), clear and stable aqueous solutions can only be obtained at pH values higher than 10. A decrease in the pH value leads to turbid and unstable solutions. This effect is not compatible with the formulation of aqueous stable and drinkable formulations with neutral or even acidic pH values. However, the pH value/phase behavior of aqueous soap solutions can be altered by the addition of other surfactants. Such a surfactant can be Rebaudioside A (RebA), a steviol glycoside from the plant Stevia rebaudiana which is used as a natural food sweetener. In a recent paper, we showed the influence of RebA on the apKa value of sodium oleate in a beverage microemulsion and on its clearing temperature. In the present paper, we report on the effect of the edible bio-surfactant RebA, on the macroscopic and microscopic phase behavior of simple aqueous sodium oleate solutions at varying pH values. The macroscopic phase behavior is investigated by visual observation and turbidity measurements. The microscopic phase behavior is analyzed by acid-base titration curves, phase-contrast and electron microscopy. It turned out that even at neutral pH, aqueous NaOl/RebA solutions can be completely clear and

Quantifying the effect of hand wash duration, soap use, ground beef debris, and drying methods on the removal of Enterobacter aerogenes on hands.

PubMed

Jensen, Dane A; Danyluk, Michelle D; Harris, Linda J; Schaffner, Donald W

2015-04-01

Hand washing is recognized as a crucial step in preventing foodborne disease transmission by mitigating crosscontamination among hands, surfaces, and foods. This research was undertaken to establish the importance of several keys factors (soap, soil, time, and drying method) in reducing microorganisms during hand washing. A nonpathogenic nalidixic acid-resistant Enterobacter aerogenes surrogate for Salmonella was used to assess the efficacy of using soap or no soap for 5 or 20 s on hands with or without ground beef debris and drying with paper towel or air. Each experiment consisted of 20 replicates, each from a different individual with ∼ 6 log CFU/ml E. aerogenes on their hands. A reduction of 1.0 ± 0.4 and 1.7 ± 0.8 log CFU of E. aerogenes was observed for a 5-s wash with no soap and a 20-s wash with soap, respectively. When there was no debris on the hands, there was no significant difference between washing with and without soap for 20 s (P > 0.05). Likewise, there was no significant difference in the reductions achieved when washing without soap, whether or not debris was on the hands (P > 0.05). A significantly greater reduction (P < 0.05) in E. aerogenes (0.5 log CFU greater reduction) was observed with soap when there was ground beef debris on the hands. The greatest difference (1.1 log CFU greater average reduction) in effectiveness occurred when ground beef debris was on the hands and a 20-s wash with water was compared with a 20-s wash with soap. Significantly greater (P < 0.05) reductions were observed with paper towel drying compared with air (0.5 log CFU greater reductions). Used paper towels may contain high bacterial levels (>4.0 log CFU per towel) when hands are highly contaminated. Our results support future quantitative microbial risk assessments needed to effectively manage risks of foodborne illness in which food workers' hands are a primary cause.

[Dmt(1)]DALDA analogues modified with tyrosine analogues at position 1.

PubMed

Cai, Yunxin; Lu, Dandan; Chen, Zhen; Ding, Yi; Chung, Nga N; Li, Tingyou; Schiller, Peter W

2016-08-01

Analogues of [Dmt(1)]DALDA (H-Dmt-d-Arg-Phe-Lys-NH2; Dmt=2',6'-dimethyltyrosine), a potent μ opioid agonist peptide with mitochondria-targeted antioxidant activity were prepared by replacing Dmt with various 2',6'-dialkylated Tyr analogues, including 2',4',6'-trimethyltyrosine (Tmt), 2'-ethyl-6'-methyltyrosine (Emt), 2'-isopropyl-6'-methyltyrosine (Imt) and 2',6'-diethyltyrosine (Det). All compounds were selective μ opioid agonists and the Tmt(1)-, Emt(1) and Det(1)-analogues showed subnanomolar μ opioid receptor binding affinities. The Tmt(1)- and Emt(1)-analogues showed improved antioxidant activity compared to the Dmt(1)-parent peptide in the DPPH radical-scavenging capacity assay, and thus are of interest as drug candidates for neuropathic pain treatment. Copyright © 2016 Elsevier Ltd. All rights reserved.

A simple geometrical model describing shapes of soap films suspended on two rings

NASA Astrophysics Data System (ADS)

Herrmann, Felix J.; Kilvington, Charles D.; Wildenberg, Rebekah L.; Camacho, Franco E.; Walecki, Wojciech J.; Walecki, Peter S.; Walecki, Eve S.

2016-09-01

We measured and analysed the stability of two types of soap films suspended on two rings using the simple conical frusta-based model, where we use common definition of conical frustum as a portion of a cone that lies between two parallel planes cutting it. Using frusta-based we reproduced very well-known results for catenoid surfaces with and without a central disk. We present for the first time a simple conical frusta based spreadsheet model of the soap surface. This very simple, elementary, geometrical model produces results surprisingly well matching the experimental data and known exact analytical solutions. The experiment and the spreadsheet model can be used as a powerful teaching tool for pre-calculus and geometry students.

Update on antibacterial soaps: the FDA takes a second look at triclosans.

PubMed

Bergstrom, Kendra Gail

2014-04-01

In December of 2013 the Food and Drug Administration announced it would look further into the safety and efficacy of the biocide triclosan and requested further safety data as part of a new review with the Environmental Protection Agency. The use of triclosan has increased exponentially since its introduction in in 1972, to the point that 75% of commercial soap brands contain triclosan and 76% of a nationwide sample of adults and children excrete triclosan in the urine. This announcement raised an important dialog about the appropriate use of all over the counter biocides. Particular concerns include whether these biocides are more effective than regular soaps, whether they may create new drug resistant bacteria, and whether they may also act as hormone disruptors in humans or the environment.

Watching your weight? The relations between watching soaps and music television and body dissatisfaction and restrained eating in young girls.

PubMed

Anschutz, Doeschka; Engels, Rutger; Leeuwe, Jan Van; Strien, Tatjana van

2009-11-01

Although previous research showed that the thin ideal provided by the media affects body image and eating behaviour in young children, less is known about specific media contents that are related to body image and eating behaviour. This study tested the associations between watching soaps and music television and body dissatisfaction and restrained eating directly, and indirectly through thin ideal internalisation. We conducted a survey in class, in which 245 girls (aged 7-9) completed scales on their television watching behaviour, thin ideal internalisation, body dissatisfaction and restrained eating. Additionally, height and weight were measured. Watching soaps and music television often was associated with higher thin ideal internalisation, which in turn was associated with higher body dissatisfaction and restrained eating. Furthermore, a direct association between watching soaps and music television and restrained eating was found. If watching other types of children's programmes or maternal encouragement to be thin were included in the models, watching soaps and music television remained an important factor, especially with regard to restrained eating. Therefore, our results suggest that if young girls watch soaps and music television often, this is related to higher restrained eating and body dissatisfaction, directly or indirectly, through higher thin ideal internalisation.

[The sensitivity and clinical course of patients with wheat-dependent exercise-induced anaphylaxis sensitized to hydrolyzed wheat protein in facial soap].

PubMed

Hiragun, Makiko; Ishii, Kaori; Hiragun, Takaaki; Shindo, Hajime; Mihara, Shoji; Matsuo, Hiroaki; Hide, Michihiro

2011-12-01

Recently an increasing number of patients with wheat-dependent exercise-induced anaphylaxis (WDEIA), developed during or after using hydrolyzed wheat protein (HWP)-containing soap (HWP-WDEIA), were reported in Japan. To clarify the relation between WDEIA and HWP-containing soap and their prognosis, we investigated the patients who visited Hiroshima University Hospital and were diagnosed as WDEIA from January 2010 to June 2011. We took detailed clinical histories, performed skin prick tests, serum immunoassays for antigen-specific IgE and basophil histamine release test, and followed up their clinical courses after the diagnosis. Among 36 patients with WDEIA, 30 patients had used only one type of HWP-soap. The patients with HWP-WDEIA were mainly women and had developed facial symptoms and angioedema. They suffered from blood pressure reductions less frequently than patients with conventional WDEIA. The levels of glutens-specific IgE were higher than those of ω-5 gliadin in patients with HWP-WDEIA (p<0.05, One-way ANOVA). All patients with HWP-WDEIA were positive against HWP in histamine release test. Among the conventional wheat antigens, glutenins induced highest histamine release from basophils of patients with HWP-WDEIA. The sensitivities of patients against glutens and glutenins were reduced over months along with the discontinuance of HWP-soap. The development of HWP-WDEIA is associated with the use of HWP-soap. The sensitivities to HWP that cross reacts with non-processed wheat may be reduced or possibly cured after the discontinuation of HWP-soap.

Parametric-Studies and Data-Plotting Modules for the SOAP

NASA Technical Reports Server (NTRS)

2008-01-01

"Parametric Studies" and "Data Table Plot View" are the names of software modules in the Satellite Orbit Analysis Program (SOAP). Parametric Studies enables parameterization of as many as three satellite or ground-station attributes across a range of values and computes the average, minimum, and maximum of a specified metric, the revisit time, or 21 other functions at each point in the parameter space. This computation produces a one-, two-, or three-dimensional table of data representing statistical results across the parameter space. Inasmuch as the output of a parametric study in three dimensions can be a very large data set, visualization is a paramount means of discovering trends in the data (see figure). Data Table Plot View enables visualization of the data table created by Parametric Studies or by another data source: this module quickly generates a display of the data in the form of a rotatable three-dimensional-appearing plot, making it unnecessary to load the SOAP output data into a separate plotting program. The rotatable three-dimensionalappearing plot makes it easy to determine which points in the parameter space are most desirable. Both modules provide intuitive user interfaces for ease of use.

Method for producing microcomposite powders using a soap solution

DOEpatents

Maginnis, Michael A.; Robinson, David A.

1996-01-01

A method for producing microcomposite powders for use in superconducting and non-superconducting applications. A particular method to produce microcomposite powders for use in superconducting applications includes the steps of: (a) preparing a solution including ammonium soap; (b) dissolving a preselected amount of a soluble metallic such as silver nitrate in the solution including ammonium soap to form a first solution; (c) adding a primary phase material such as a single phase YBC superconducting material in particle form to the first solution; (d) preparing a second solution formed from a mixture of a weak acid and an alkyl-mono-ether; (e) adding the second solution to the first solution to form a resultant mixture; (f) allowing the resultant mixture to set until the resultant mixture begins to cloud and thicken into a gel precipitating around individual particles of the primary phase material; (g) thereafter drying the resultant mixture to form a YBC superconducting material/silver nitrate precursor powder; and (h) calcining the YBC superconducting material/silver nitrate precursor powder to convert the silver nitrate to silver and thereby form a YBC/silver microcomposite powder wherein the silver is substantially uniformly dispersed in the matrix of the YBC material.

Associations between presence of handwashing stations and soap in the home and diarrhoea and respiratory illness, in children less than five years old in rural western Kenya.

PubMed

Kamm, K B; Feikin, D R; Bigogo, G M; Aol, G; Audi, A; Cohen, A L; Shah, M M; Yu, J; Breiman, R F; Ram, P K

2014-04-01

We tested whether soap presence in the home or a designated handwashing station was associated with diarrhoea and respiratory illness in Kenya. In April 2009, we observed presence of a handwashing station and soap in households participating in a longitudinal health surveillance system in rural Kenya. Diarrhoea and acute respiratory illness (ARI) in children < 5 years old were identified using parent-reported syndromic surveillance collected January-April 2009. We used multivariate generalised linear regression to estimate differences in prevalence of illness between households with and without the presence of soap in the home and a handwashing station. Among 2547 children, prevalence of diarrhoea and ARI was 2.3 and 11.4 days per 100 child-days, respectively. Soap was observed in 97% of households. Children in households with soap had 1.3 fewer days of diarrhoea/100 child-days (95% CI -2.6, -0.1) than children in households without soap. ARI prevalence was not associated with presence of soap. A handwashing station was identified in 1.4% of households and was not associated with a difference in diarrhoea or ARI prevalence. Soap presence in the home was significantly associated with reduced diarrhoea, but not ARI, in children in rural western Kenya. Whereas most households had soap in the home, almost none had a designated handwashing station, which may prevent handwashing at key times of hand contamination. © 2014 John Wiley & Sons Ltd.

Associations between presence of handwashing stations and soap in the home and diarrhoea and respiratory illness, in children less than five years old in rural western Kenya

PubMed Central

Kamm, K. B.; Feikin, D. R.; Bigogo, G. M.; Aol, G.; Audi, A.; Cohen, A. L.; Shah, M. M.; Yu, J.; Breiman, R. F.; Ram, P. K.

2015-01-01

OBJECTIVE We tested whether soap presence in the home or a designated handwashing station was associated with diarrhoea and respiratory illness in Kenya. METHODS In April 2009, we observed presence of a handwashing station and soap in households participating in a longitudinal health surveillance system in rural Kenya. Diarrhoea and acute respiratory illness (ARI) in children < 5 years old were identified using parent-reported syndromic surveillance collected January–April 2009. We used multivariate generalised linear regression to estimate differences in prevalence of illness between households with and without the presence of soap in the home and a handwashing station. RESULTS Among 2547 children, prevalence of diarrhoea and ARI was 2.3 and 11.4 days per 100 child-days, respectively. Soap was observed in 97% of households. Children in households with soap had 1.3 fewer days of diarrhoea/100 child-days (95% CI −2.6, −0.1) than children in households without soap. ARI prevalence was not associated with presence of soap. A handwashing station was identified in 1.4% of households and was not associated with a difference in diarrhoea or ARI prevalence. CONCLUSIONS Soap presence in the home was significantly associated with reduced diarrhoea, but not ARI, in children in rural western Kenya. Whereas most households had soap in the home, almost none had a designated handwashing station, which may prevent handwashing at key times of hand contamination. PMID:24405627

SOAP 2.0: A Tool to Estimate the Photometric and Radial Velocity Variations Induced by Stellar Spots and Plages

NASA Astrophysics Data System (ADS)

Dumusque, X.; Boisse, I.; Santos, N. C.

2014-12-01

This paper presents SOAP 2.0, a new version of the Spot Oscillation And Planet (SOAP) code that estimates in a simple way the photometric and radial velocity (RV) variations induced by active regions. The inhibition of the convective blueshift (CB) inside active regions is considered, as well as the limb brightening effect of plages, a quadratic limb darkening law, and a realistic spot and plage contrast ratio. SOAP 2.0 shows that the activity-induced variation of plages is dominated by the inhibition of the CB effect. For spots, this effect becomes significant only for slow rotators. In addition, in the case of a major active region dominating the activity-induced signal, the ratio between the FWHM and the RV peak-to-peak amplitudes of the cross correlation function can be used to infer the type of active region responsible for the signal for stars with v sin i <=8 km s-1. A ratio smaller than three implies a spot, while a larger ratio implies a plage. Using the observation of HD 189733, we show that SOAP 2.0 manages to reproduce the activity variation as well as previous simulations when a spot is dominating the activity-induced variation. In addition, SOAP 2.0 also reproduces the activity variation induced by a plage on the slowly rotating star α Cen B, which is not possible using previous simulations. Following these results, SOAP 2.0 can be used to estimate the signal induced by spots and plages, but also to correct for it when a major active region is dominating the RV variation. . The work in this paper is based on observations made with the MOST satellite, the HARPS instrument on the ESO 3.6 m telescope at La Silla Observatory (Chile), and the SOPHIE instrument at the Observatoire de Haute Provence (France).

Effectiveness of liquid soap vs. chlorhexidine gluconate for the removal of Clostridium difficile from bare hands and gloved hands.

PubMed

Bettin, K; Clabots, C; Mathie, P; Willard, K; Gerding, D N

1994-11-01

To compare liquid soap versus 4% chlorhexidine gluconate in 4% alcohol for the decontamination of bare or gloved hands inoculated with an epidemic strain of Clostridium difficile. C difficile (6.7 log10 colony-forming units [CFU], 47% spores), was seeded onto bare or latex gloved hands of ten volunteers and allowed to dry. Half the volunteers initially washed with soap and half with chlorhexidine, followed by the other agent 1 week later. Cultures were done with Rodac plates at three sites on the hand: finger/thumbtips, the palmar surfaces of the fingers, and the palm. Statistical comparison was by paired Student's t test. On bare hands, soap and chlorhexidine did not differ in residual bacterial counts on the finger/thumbtips (log10 CFU, 2.0 and 2.1, P = NS) and fingers (log10 CFU, 2.4 and 2.5, P = NS). Counts were too high on bare palms to quantitate. On gloved hands, soap was more effective than chlorhexidine on fingers (log10 CFU 1.3 and 1.7, P < .01) and palms (log10 CFU 1.5 and 2.0, P < .01), but not finger/thumbtips (log10 CFU 1.6 with each, P = NS). Residual C difficile counts were lower on gloved hands than bare hands (P < 0.01 to < 0.0001). The two agents did not differ significantly in residual counts of C difficile on bare hands, but on gloved hands residual counts were lower following soap wash than following chlorhexidine wash. These observations support the use of either soap or chlorhexidine as a handwash for removal of C difficile, but efficacy in the prevention of C difficile transmission must be determined by prospective clinical trials.

Impact of Regular Soap Provision to Primary Schools on Hand Washing and E. coli Hand Contamination among Pupils in Nyanza Province, Kenya: A Cluster-Randomized Trial

PubMed Central

Saboori, Shadi; Greene, Leslie E.; Moe, Christine L.; Freeman, Matthew C.; Caruso, Bethany A.; Akoko, Daniel; Rheingans, Richard D.

2013-01-01

We assessed whether supplying soap to primary schools on a regular basis increased pupil hand washing and decreased Escherichia coli hand contamination. Multiple rounds of structured observations of hand washing events after latrine use were conducted in 60 Kenyan schools, and hand rinse samples were collected one time in a subset of schools. The proportion of pupils observed practicing hand washing with soap (HWWS) events was significantly higher in schools that received a soap provision intervention (32%) and schools that received soap and latrine cleaning materials (38%) compared with controls (3%). Girls and boys had similar hand washing rates. There were non-significant reductions in E. coli contamination among intervention school pupils compared with controls. Removing the barrier of soap procurement can significantly increase availability of soap and hand washing among pupils; however, we discuss limitations in the enabling policy and institutional environment that may have prevented reaching desired levels of HWWS. PMID:23939707

Impact of regular soap provision to primary schools on hand washing and E. coli hand contamination among pupils in Nyanza Province, Kenya: a cluster-randomized trial.

PubMed

Saboori, Shadi; Greene, Leslie E; Moe, Christine L; Freeman, Matthew C; Caruso, Bethany A; Akoko, Daniel; Rheingans, Richard D

2013-10-01

We assessed whether supplying soap to primary schools on a regular basis increased pupil hand washing and decreased Escherichia coli hand contamination. Multiple rounds of structured observations of hand washing events after latrine use were conducted in 60 Kenyan schools, and hand rinse samples were collected one time in a subset of schools. The proportion of pupils observed practicing hand washing with soap (HWWS) events was significantly higher in schools that received a soap provision intervention (32%) and schools that received soap and latrine cleaning materials (38%) compared with controls (3%). Girls and boys had similar hand washing rates. There were non-significant reductions in E. coli contamination among intervention school pupils compared with controls. Removing the barrier of soap procurement can significantly increase availability of soap and hand washing among pupils; however, we discuss limitations in the enabling policy and institutional environment that may have prevented reaching desired levels of HWWS.

Exposure to disinfectants (soap or hydrogen peroxide) increases tolerance to permethrin in Anopheles gambiae populations from the city of Yaoundé, Cameroon

PubMed Central

2014-01-01

Background The rapid expansion of insecticide resistance is limiting the efficiency of malaria vector control interventions. However, current knowledge of factors inducing pyrethroid resistance remains incomplete. In the present study, the role of selection at the larval stage by disinfectants, such as soap and hydrogen peroxide (H2O2), on adult mosquito resistance to permethrin was investigated. Methods Field Anopheles gambiae sensu lato larvae, were exposed to variable concentrations of soap and H2O2. Larvae surviving to acute toxicity assays after 24 hours were reared to the adult stage and exposed to permethrin. The susceptibility level of adults was compared to the untreated control group. The effect of soap or hydrogen peroxide selection on the length of larval development and emergence rate was assessed. Result Larval bioassays analysis showed a more acute effect of hydrogen peroxide on mosquito larvae compared to soap. The regression lines describing the dose mortality profile showed higher mean and variance to hydrogen peroxide than to soap. The duration of larval development (<5 days) and adults emergence rates (1 to 77%) were shorter and lower compare to control. Anopheles gambiae s.l. larvae surviving to selection with either soap or hydrogen peroxide or both, produced adults who were up to eight-times more resistant to permethrin than mosquitoes from the untreated control group. Conclusion The present study shows that selective pressure exerted by non-insecticidal compounds such as soap and hydrogen peroxide affect An. gambiae s.l. tolerance to pyrethroids. This requires further studies with regard to the adaptation of An. gambiae s.l. to polluted habitats across sub-Saharan Africa cities. PMID:25086741

Exposure to disinfectants (soap or hydrogen peroxide) increases tolerance to permethrin in Anopheles gambiae populations from the city of Yaoundé, Cameroon.

PubMed

Antonio-Nkondjio, Christophe; Youmsi-Goupeyou, Marlene; Kopya, Edmond; Tene-Fossog, Billy; Njiokou, Flobert; Costantini, Carlo; Awono-Ambene, Parfait

2014-08-03

The rapid expansion of insecticide resistance is limiting the efficiency of malaria vector control interventions. However, current knowledge of factors inducing pyrethroid resistance remains incomplete. In the present study, the role of selection at the larval stage by disinfectants, such as soap and hydrogen peroxide (H2O2), on adult mosquito resistance to permethrin was investigated. Field Anopheles gambiae sensu lato larvae, were exposed to variable concentrations of soap and H2O2. Larvae surviving to acute toxicity assays after 24 hours were reared to the adult stage and exposed to permethrin. The susceptibility level of adults was compared to the untreated control group. The effect of soap or hydrogen peroxide selection on the length of larval development and emergence rate was assessed. Larval bioassays analysis showed a more acute effect of hydrogen peroxide on mosquito larvae compared to soap. The regression lines describing the dose mortality profile showed higher mean and variance to hydrogen peroxide than to soap. The duration of larval development (<5 days) and adults emergence rates (1 to 77%) were shorter and lower compare to control. Anopheles gambiae s.l. larvae surviving to selection with either soap or hydrogen peroxide or both, produced adults who were up to eight-times more resistant to permethrin than mosquitoes from the untreated control group. The present study shows that selective pressure exerted by non-insecticidal compounds such as soap and hydrogen peroxide affect An. gambiae s.l. tolerance to pyrethroids. This requires further studies with regard to the adaptation of An. gambiae s.l. to polluted habitats across sub-Saharan Africa cities.

Drainage Behavior in Soap Films Above and Below the CMC

NASA Astrophysics Data System (ADS)

Berg, S.; Adelizzi, E. A.; Troian, S. M.

2003-11-01

We investigate through laser interferometry the drainage behavior of Newtonian soap films initially entrained on a fiber frame at small and constant capillary number. The initial film thickness is sufficiently small that gravitational drainage is presumed minimal. The drainage of rigid soap films by capillary forces alone should proceed according to h(t) ˜ t^- 1/2. Our experimental results show much more rapid drainage with exponents as large as -2, especially for those solutions whose surfactant concentrations are below the CMC. Video recordings of the entire film surface reveal a variety of structures during the drainage process, some attributable to marginal regeneration. Though still a controversial issue, this regeneration process is believed to be caused by surfactant accumulation in the meniscus region (1). We show that modification of the relevant capillary drainage equation to account for Marangoni effects through a course-grained slip condition at the air-liquid interface produces exponents in better agreement with experimental findings. (1) V. A. Nierstrasz and G. Frens, JCIS 215, 28 (1999).

Intrinsic Klebsiella pneumoniae contamination of liquid germicidal hand soap containing chlorhexidine.

PubMed

Brooks, Steven E; Walczak, Mary A; Malcolm, Sharon; Hameed, Rizwanullah

2004-10-01

We describe intrinsic contamination with Klebsiella pneumoniae occurring during the manufacture of germicidal hand soap, labeled as containing 2% chlorhexidine, used throughout a 350-bed community medical center. A 3-year retrospective study failed to find evidence of increased incidence of clinical isolates of this strain.

Time-Dependent ATR-FTIR Spectroscopic Studies on Fatty Acid Diffusion and the Formation of Metal Soaps in Oil Paint Model Systems.

PubMed

Baij, Lambert; Hermans, Joen J; Keune, Katrien; Iedema, Piet

2018-06-18

The formation of metal soaps (metal complexes of saturated fatty acids) is a serious problem affecting the appearance and structural integrity of many oil paintings. Tailored model systems for aged oil paint and time-dependent attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy were used to study the diffusion of palmitic acid and subsequent metal soap crystallization. The simultaneous presence of free saturated fatty acids and polymer-bound metal carboxylates leads to rapid metal soap crystallization, following a complex mechanism that involves both acid and metal diffusion. Solvent flow, water, and pigments all enhance metal soap crystallization in the model systems. These results contribute to the development of paint cleaning strategies, a better understanding of oil paint degradation, and highlight the potential of time-dependent ATR-FTIR spectroscopy for studying dynamic processes in polymer films. © 2018 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

The pH of the main Brazilian commercial moisturizers and liquid soaps: considerations on the repair of the skin barrier*

PubMed Central

Gonçalves, Giovana M; Brianezi, Gabrielli; Miot, Hélio Amante

2017-01-01

The pH of the skin is slightly acidic (4.6 to 5.8) which is important for appropriate antibacterial, antifungal, constitution of barrier function, as well as structuring and maturation of the stratum corneum. This study aimed to evaluate the pH of the main commercial moisturizers and liquid soaps in Brazil. Thus, pH of the products was quantified by pH meter in three measurements. A total of 38 moisturizers and six commercial liquid soaps were evaluated. Mean pH of 63% and 50% of the moisturizing and liquid soaps presented results above 5.5, disfavoring repair, function, and synthesis of dermal barrier. PMID:29166523

The pH of the main Brazilian commercial moisturizers and liquid soaps: considerations on the repair of the skin barrier.

PubMed

Gonçalves, Giovana M; Brianezi, Gabrielli; Miot, Hélio Amante

2017-01-01

The pH of the skin is slightly acidic (4.6 to 5.8) which is important for appropriate antibacterial, antifungal, constitution of barrier function, as well as structuring and maturation of the stratum corneum. This study aimed to evaluate the pH of the main commercial moisturizers and liquid soaps in Brazil. Thus, pH of the products was quantified by pH meter in three measurements. A total of 38 moisturizers and six commercial liquid soaps were evaluated. Mean pH of 63% and 50% of the moisturizing and liquid soaps presented results above 5.5, disfavoring repair, function, and synthesis of dermal barrier.

An expeditious synthesis of imatinib and analogues utilising flow chemistry methods.

PubMed

Hopkin, Mark D; Baxendale, Ian R; Ley, Steven V

2013-03-21

A flow-based route to imatinib, the API of Gleevec, was developed and the general procedure then used to generate a number of analogues which were screened for biological activity against Abl1. The flow synthesis required minimal manual intervention and was achieved despite the poor solubility of many of the reaction components.

Occurrence of heterotrophic and coliform bacteria in liquid hand soaps from bulk refillable dispensers in public facilities.

PubMed

Chattman, Marisa; Gerba, Sheri L; Maxwell, Charles P

2011-03-01

The goal of the study discussed in this article was to determine the occurrence of heterotrophic and coliform bacteria in liquid soap from bulk refillable dispensers, obtained from restrooms in a variety of public facilities. A total of 541 samples was collected from five U.S. cities. Liquid soap from dispensers in public areas was found to contain heterotrophic and coliform bacterial numbers averaging more than 106 CFU/mL in 24.8% of the dispensers.

Authentic ESL Spoken Materials: Soap Opera and Sitcom versus Natural Conversation

ERIC Educational Resources Information Center

Al-Surmi, Mansoor Ali

2012-01-01

TV shows, especially soap operas and sitcoms, are usually considered by ESL practitioners as a source of authentic spoken conversational materials presumably because they reflect the linguistic features of natural conversation. However, practitioners might be faced with the dilemma of how to evaluate whether such conversational materials reflect…

Recommendations and requirements for soap and hand rub dispensers in healthcare facilities.

PubMed

Assadian, Ojan; Kramer, Axel; Christiansen, Bärbel; Exner, Martin; Martiny, Heike; Sorger, Arno; Suchomel, Miranda

2012-01-01

Hand hygiene is one of the most important measures to prevent transmission of infectious agents and plays a major role in prevention of infection in any type of healthcare setting. While requirements for the efficacy of hand disinfectants are defined in European testing norms such as the EN 1500 for hygienic hand disinfection or EN 12791 for surgical hand preparation, no specific recommendations for hand rub dispensers and liquid soap dispensers have been given yet. Therefore, the intention of the present recommendation on soap and hand rub dispensers in healthcare facilities is to close this gap and to enhance future improvement of dispenser functionality and design. Regardless of manufacture and design of a hand rub or liquid soap dispensers the following requirements shall be met in healthcare facilities:Triggering the dispenser must be possible without using hands. Sensor- or elbow-operated dispensers both fulfill this requirement. Dispensers must be only refillable in a modality where the content, be it a hand rub or liquid soap, cannot be contaminated. This is achieved best by using replaceable cartridge systems. Refilling through "top-up" must not be possible. The disperser should allow usage of different types of cartridges made by different manufacturers. Dispensers must be operated and maintained such that a microbial contamination of the pump nozzle may easily be avoided. It must be possible to identify the products used in a dispenser easily and without any manipulation. Identifying the type of product, be it a hand rub or a liquid soap, as well as reading the product's name and critical manufacturers' warnings must be possible at any time. The disperser must allow identification of the level of the used product without any further manipulation at any time. The design of the dispenser must allow easy cleaning and disinfection the outside and inside of the dispenser. The manufacturer of the dispenser must provide the user with information on applicable

The generation of two-dimensional vortices by transverse oscillation of a soap film

DOE Office of Scientific and Technical Information (OSTI.GOV)

Afenchenko, V.O.; Ezersky, A.B.; Kiyashko, S.V.

1998-02-01

An experimental investigation of the dynamics of horizontal soap films stretched over circular or square boundaries undergoing periodic transverse oscillations at frequencies in the range 20{endash}200 Hz is reported. Concomitant with modes of transverse flexural oscillations, it was observed that two-dimensional vortices in the plane of the film are excited. The vortices may be either (i) large, scaling with the size of the cavity or (ii) small, localized at a wavelength or half-wavelength of the membrane modes. In the experiments a stable generation of one, two, {hor_ellipsis}, ten pairs of counter-rotating vortices were observed in finite regions of amplitude-frequency parametermore » space. The circulation strength of vortices in a given vortex pattern increases with increasing external forcing and with decreasing soap film thickness. A theoretical model based on the wave-boundary interaction of excited Marangoni waves reveals a vorticity generation mechanism active in vibrating soap films. This model shows that vorticity is generated throughout the entire liquid volume by viscous diffusion, and qualitatively reproduces many steady vortex patterns observed in the experiment. However, the model cannot explain the existence of the sometimes intense vortices observed far from the film boundary that do not appear to be generated by diffusive processes. {copyright} {ital 1998 American Institute of Physics.}« less

The pH of commonly available soaps, liquid cleansers, detergents and alcohol gels.

PubMed

Boonchai, Waranya; Iamtharachai, Pacharee

2010-01-01

The hydrogen ion concentration (pH) of a cleanser certainly has an impact on skin condition. Dermatologists always need to recommend a cleanser to patients with hand dermatitis or sensitive skin; particularly during the outbreak of swine (AH1N1 virus) influenza, frequent hand washing and alcohol gel cleansing were greatly recommended. The purpose of this study was to evaluate the pH of various commonly available cleansers and alcohol gels on the market to assess patient comfort in using such products and to make good recommendations to our patients. Multiple brands of liquid cleansers, dishwashing liquids, soaps, laundry detergents, and alcohol gels commonly available on the market were assessed for pH by using a pH meter and pH-indicator strips. The pH assessment imitated real-life conditions by diluting each cleanser with tap water and then comparing the changed pH. The pH levels of liquid cleansers, dishwashing liquids, a beauty bar, and alcohol gels were acidic to neutral and compatible with normal skin pH. Most bar soaps, baby soaps, and powdered laundry detergents had a pH in the alkali range. The pH of concentrated cleansers was slightly different from that of their dissolved forms. Regarding the antiseptic property and pH of the cleansers, alcohol gels with moisturizers appeared to be the best hand cleansers to recommend to our patients.

Antimicrobial efficacy of soap and water hand washing versus an alcohol-based hand cleanser.

PubMed

Holton, Ronald H; Huber, Michaell A; Terezhalmy, Geza T

2009-12-01

The emergence of alcohol-based hand cleansers may represent an alternative to soap and water in the clinical dental setting. In this study, the antimicrobial efficacy of traditional hand washing vs. a unique alcohol-based hand cleanser with persistence was evaluated. Two experienced dentists participated over a 10-day period. On days 1-5, each clinician used an antibacterial liquid soap (Dial, Dial Corporation, Scottsdale, AZ). Days 6-10, an alcohol-based hand cleanser (Triseptin Water Optional, Healthpoint Surgical, Fort Worth, TX) was used. Sampling was by modified glove juice technique. The results indicate that the alcohol-based hand cleanser dramatically outperforms the traditional hand washing agent in the general dental setting.

Chemists Clean Up: A History and Exploration of the Craft of Soapmaking--How Soap Came To Be Common in America.

ERIC Educational Resources Information Center

Kostka, Kimberly L.; McKay, David D.

2002-01-01

Explores the confluence of cultural and technological changes that led to the transformation of soap into a ubiquitous and well-used object. Picks up the timeline for the development of soap in the early American republic when soapmaking was a householder's task. Traces the rise of the American cleanliness movement and correlates the rise to…

Safety in Outdoor Adventure Programs. S.O.A.P. Safety Policy.

ERIC Educational Resources Information Center

MacDonald, Wayne, Comp.; And Others

Drafted in 1978 as a working document for Safety in Outdoor Adventure Programs (S.O.A.P.) by a council of outdoor adventure programmers, checklists outline standard accepted safety policy for Outdoor Adventure Programs and Wilderness Adventure Programs conducted through public or private agencies in California. Safety policy emphasizes: the…

Teaching with Soap: Examples of Project-Based Units for Students and Future Educators

ERIC Educational Resources Information Center

Farrell, Ivan; Hamed, Kastro M.

2016-01-01

This article describes the use of project-based instruction in activities and labs intended to develop higher-order thinking skills with high school students and pre-service teachers through the use of soap making.

Relativistic strings - From soap films to a grand unified theory

NASA Astrophysics Data System (ADS)

Nesterenko, V. V.

1986-11-01

The concept of relativistic strings is considered in connection with the theory of minimal surfaces (e.g., soap films stretched onto closed wire contours). The role of relativistic strings in hadron physics is discussed. Attention is then given to the creation of a grand unified theory on the basis of the superstring concept. Finally, the role of relativistic strings in cosmology is examined.

"Marginal pinching" in soap films

NASA Astrophysics Data System (ADS)

Aradian, A.; Raphaël, E.; de Gennes, P.-G.

2001-09-01

We discuss the behaviour of a thin soap film facing a frame element: the pressure in the Plateau border around the frame is lower than the film pressure, and the film thins out over a certain distance λ(t), due to the formation of a well-localized pinched region of thickness h(t) and extension w(t). We construct a hydrodynamic theory for this thinning process, assuming a constant surface tension: Marangoni effects are probably important only at late stages, where instabilities set in. We find λ(t) ~ t1/4, and for the pinch dimensions, h(t) ~ t-1/2 and w(t) ~ t-1/4. These results may play a useful role for the discussion of later instabilities leading to a global film thinning and drainage, as first discussed by K. Mysels under the name "marginal regeneration".

Microbial characterization and degradation of linear alkylbenzene sulfonate in an anaerobic reactor treating wastewater containing soap powder.

PubMed

Carosia, Mariana Fronja; Okada, Dagoberto Yukio; Sakamoto, Isabel Kimiko; Silva, Edson Luiz; Varesche, Maria Bernadete Amâncio

2014-09-01

The aim of this study was to evaluate the removal of linear alkylbenzene sulfonate (LAS) in an anaerobic fluidized bed reactor (AFBR) treating wastewater containing soap powder as LAS source. At Stage I, the AFBR was fed with a synthetic substrate containing yeast extract and ethanol as carbon sources, and without LAS; at Stage II, soap powder was added to this synthetic substrate obtaining an LAS concentration of 14 ± 3 mg L(-1). The compounds of soap powder probably inhibited some groups of microorganisms, increasing the concentration of volatile fatty acids (VFA) from 91 to 143 mg HAc L(-1). Consequently, the LAS removal rate was 48 ± 10% after the 156 days of operation. By sequencing, 16S rRNA clones belonging to the phyla Proteobacteria and Synergistetes were identified in the samples taken at the end of the experiment, with a remarkable presence of Dechloromonas sp. and Geobacter sp. Copyright © 2014 Elsevier Ltd. All rights reserved.

Outbreak of Serratia marcescens in a neonatal intensive care unit: contaminated unmedicated liquid soap and risk factors.

PubMed

Buffet-Bataillon, S; Rabier, V; Bétrémieux, P; Beuchée, A; Bauer, M; Pladys, P; Le Gall, E; Cormier, M; Jolivet-Gougeon, A

2009-05-01

This study describes an outbreak of Serratia marcescens and its investigation and control in a neonatal intensive care unit (NICU). During a three-month period, five infants were colonised or infected by a single strain of S. marcescens. A case-control study, culture surveys and pulse-field gel electrophoresis analysis implicated a bottle soap dispenser as a reservoir of S. marcescens (P=0.032). Infants with S. marcescens colonisation or infection were also more likely to have been exposed to a central or percutaneous venous catheter (P=0.05) and had had longer exposure to endotracheal intubation (P=0.05). Soap dispensers are used in many hospitals and may be an unrecognised source of nosocomial infections. This potential source of infection could be reduced by using 'airless' dispensers which have no air intake for the distribution of soap. Prompt intervention and strict adherence to alcoholic hand disinfection were the key factors that led to the successful control of this outbreak.

Single treatment with ethanol hand rub is ineffective against human rhinovirus--hand washing with soap and water removes the virus efficiently.

PubMed

Savolainen-Kopra, Carita; Korpela, Terttu; Simonen-Tikka, Marja-Leena; Amiryousefi, Ali; Ziegler, Thedi; Roivainen, Merja; Hovi, Tapani

2012-03-01

Ethanol-containing hand rubs are used frequently as a substitute for hand washing with water and soap. However, not all viruses are inactivated by a short term rubbing with alcohol. The capacity of a single round of instructed and controlled hand cleaning with water and soap or ethanol-containing hand rub, respectively, was tested for removal of human rhinovirus administered onto the skin of healthy volunteers on the back of the hands. Hand washing with soap and water appeared to be much more efficient for removing rhinoviruses from skin than rubbing hands with an ethanol-containing disinfectant. After washing with soap and water the virus was detected in 3/9 (33.3%) test persons from the left hand and 1/9 (11.1%) cases from the right hand, whereas the virus was detected invariably by real-time RT-PCR from both hands after cleaning with alcohol hand rub (P-value <0.01). Both substances evaluated clinically were also tested in vitro for virucidal efficacy against Human rhinovirus2 (HRV2) using a standardized assay. Both tested substances were poor within the contact time used in the hand-cleaning test. In conclusion, thorough and conventional hand washing with water and soap can clean efficiently hands contaminated with the virus responsible for an extensive share of common cold episodes. Copyright © 2012 Wiley Periodicals, Inc.

Soap film flows: Statistics of two-dimensional turbulence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vorobieff, P.; Rivera, M.; Ecke, R.E.

1999-08-01

Soap film flows provide a very convenient laboratory model for studies of two-dimensional (2-D) hydrodynamics including turbulence. For a gravity-driven soap film channel with a grid of equally spaced cylinders inserted in the flow, we have measured the simultaneous velocity and thickness fields in the irregular flow downstream from the cylinders. The velocity field is determined by a modified digital particle image velocimetry method and the thickness from the light scattered by the particles in the film. From these measurements, we compute the decay of mean energy, enstrophy, and thickness fluctuations with downstream distance, and the structure functions of velocity,more » vorticity, thickness fluctuation, and vorticity flux. From these quantities we determine the microscale Reynolds number of the flow R{sub {lambda}}{approx}100 and the integral and dissipation scales of 2D turbulence. We also obtain quantitative measures of the degree to which our flow can be considered incompressible and isotropic as a function of downstream distance. We find coarsening of characteristic spatial scales, qualitative correspondence of the decay of energy and enstrophy with the Batchelor model, scaling of energy in {ital k} space consistent with the k{sup {minus}3} spectrum of the Kraichnan{endash}Batchelor enstrophy-scaling picture, and power-law scalings of the structure functions of velocity, vorticity, vorticity flux, and thickness. These results are compared with models of 2-D turbulence and with numerical simulations. {copyright} {ital 1999 American Institute of Physics.}« less

A randomized, double-blind, placebo-controlled study to evaluate the efficacy in AD of liquid soap containing 12% ammonium lactate + 20% urea.

PubMed

Amichai, B; Grunwald, M H

2009-12-01

Atopic dermatitis (AD) is a common chronic skin disease, which mainly affects children. Xerosis is one of the most troublesome signs of the disease. The aim of this study was to evaluate the efficacy of liquid soap containing 12% ammonium lactate + 20% urea in patients with AD. In a randomized, double-blind study, 36 patients (both male and female patients; age range 3-40 years) with mild to moderate AD were enrolled. Patients were divided randomly into two groups, in a ratio of 2:1 (active:placebo). The prescribed soap was used on a daily basis during a shower for 3 weeks. All patients continued all other systemic or topical medication but avoided any other soap or emollients. After 3 weeks of treatment, efficacy was assessed both by clinician and patient. There were significant improvements in scaling (P < 0.0001), skin dryness (P < 0.0001) and redness (P = 0.03) as rated by the investigator, and subjective patient assessment of itch also improved (P < 0.001) in the study group compared with the control group. The liquid soap was found to be effective in patients with AD, as use of this soap in patients with stable mild to moderate AD improved the parameters studied.

Preventive effects of topical washing with miconazole nitrate-containing soap to diaper candidiasis in hospitalized elderly patients: A prospective, double-blind, placebo-controlled study.

PubMed

Takahashi, Hidenori; Oyama, Noritaka; Tanaka, Izumi; Hasegawa, Michiko; Hirano, Kaori; Shimada, Chieko; Hasegawa, Minoru

2017-07-01

The objective of the present randomized, double-blind trial was to evaluate the efficacy and safety of daily washing with miconazole nitrate-containing soap for candidiasis at diaper-covered sites in elderly subjects under long-term inpatient care. To confirm the onset and disappearance of candidiasis, we microscopically evaluated the existence of the pseudohyphae and/or blastoconidia of Candida spp. We enrolled 75 elderly patients who wore diapers all day in the hospital or nursing home. Patients were randomly assigned to receive treatment with either miconazole soap or miconazole-free placebo soap, and 28 patients in the miconazole group and 27 patients in the placebo group were followed for 4 weeks. Although washing with miconazole soap did not affect the frequency of pseudohyphae/blastoconidia-positive patients, it significantly inhibited the positive conversion of pseudohyphae/blastoconidia compared with the placebo group. As a result, the frequency of patients positive for pseudohyphae/blastoconidia was significantly lower in the miconazole group than in the control group at 4 weeks (17.9% vs 44.4%). Clinically apparent diaper candidiasis did not develop in either group. Washing with miconazole soap was a significant independent factor for reducing the cases positive for pseudohyphae/blastoconidia, while diarrhea and heart failure were significant factors associated with an increase in the positive rate at the end-point. Severe adverse effects were not found in any patients. Thus, washing with miconazole soap is well-tolerated and can inhibit the positive conversion of Candida in patients wearing diapers. Therefore, maintenance of genital hygiene using this soap may prophylactically decrease the overall prevalence of patients with diaper candidiasis. © 2017 Japanese Dermatological Association.

11. 4TH FLOOR, HOTEL SOAP LINE No. 6 TO NORTHEAST, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. 4TH FLOOR, HOTEL SOAP LINE No. 6 TO NORTHEAST, WITH WRAPPER (LEFT), PRESS (CENTER), AND CUTTER (RIGHT, BEHIND CHUTE); BUCKET CONVEYOR AT RIGHT MOVED WASTE FROM PRESS TO 5TH FLOOR FOR RE-MANUFACTURE - Colgate & Company Jersey City Plant, Building No. B-14, 54-58 Grand Street, Jersey City, Hudson County, NJ

Gelling Mechanism of Aluminum Di-Soaps in Oils

NASA Astrophysics Data System (ADS)

Wang, Xiaorong; Rackaitis, Mindaugas

2009-03-01

This work demonstrates that aluminum di-soaps form nano-sized spherical micelles in the oils and that the aggregation of these micelles forms a network that gives rise to a gel formation -- thereby refuting a long-held belief that the gel formation was the result of linear polymeric chains of aluminum association. The discovery of such aluminum nano-particles could expand application of these materials to new technologies because these materials are chemically inert, odorless and nontoxic, and have been widely used in greases, paints, gels, cosmetics, drugs and foods.

Adolescents' Interpretations of the Birth Control Behavior of a Soap Opera Couple.

ERIC Educational Resources Information Center

Walsh-Childers, Kim

A study investigated whether adolescents' schemas about contraceptive use would influence their perceptions that a soap opera couple used birth control during sex. The study also examined the effects of increasing explicitness of characters' conversations about contraceptives on viewers' perceptions of the couple's contraceptive use. Thirty-six…

Secure Service Invocation in a Peer-to-Peer Environment Using JXTA-SOAP

NASA Astrophysics Data System (ADS)

Laghi, Maria Chiara; Amoretti, Michele; Conte, Gianni

The effective convergence of service-oriented architectures (SOA) and peer-to-peer (P2P) is an urgent task, with many important applications ranging from e-business to ambient intelligence. A considerable standardization effort is being carried out from both SOA and P2P communities, but a complete platform for the development of secure, distributed applications is still missing. In this context, the result of our research and development activity is JXTA-SOAP, an official extension for JXTA enabling Web Service sharing in peer-to-peer networks. Recently we focused on security aspects, providing JXTA-SOAP with a general security management system, and specialized policies that target both J2SE and J2ME versions of the component. Among others, we implemented a policy based on Multimedia Internet KEYing (MIKEY), which can be used to create a key pair and all the required parameters for encryption and decryption of service messages in consumer and provider peers running on resource-constrained devices.

Influence of chain length and double bond on the aqueous behavior of choline carboxylate soaps.

PubMed

Rengstl, Doris; Diat, Olivier; Klein, Regina; Kunz, Werner

2013-02-26

In preceding studies, we demonstrated that choline carboxylates ChC(m) with alkyl chain lengths of m = 12 - 18 are highly water-soluble (for m = 12, soluble up to 93 wt % soap and 0 °C). In addition, choline soaps are featured by an extraordinary lyotropic phase behavior. With decreasing water concentration, the following phases were found: micellar phase (L(1)), discontinuous cubic phase (I(1)' and I(1)"), hexagonal phase (H(1)), bicontinuous cubic phase (V(1)), and lamellar phase (L(α)). The present work is also focused on the lyotropic phase behavior of choline soaps but with shorter alkyl chains or different alkyl chain properties. We have investigated the aqueous phase behavior of choline soaps with C(8) and C(10) chain-lengths (choline octanoate and choline decanoate) and with a C(18) chain-length with a cis-double bond (choline oleate). We found that choline decanoate follows the lyotropic phase behavior of the longer-chain homologues mentioned above. Choline octanoate in water shows no discontinuous cubic phases, but an extended, isotropic micellar solution phase. In addition, choline octanoate is at the limit between a surfactant and a hydrotrope. The double bond in choline oleate leads also to a better solubility in water and a decrease of the solubilization temperature. It also influences the Gaussian curvature of the aggregates which results in a loss of discontinuous cubic phases in the binary phase diagram. The different lyotropic mesophases were identified by the penetration scan technique with polarizing light microscope and visual observations. To clarify the structural behavior small (SAXS) and wide (WAXS) angle X-ray scattering were performed. To further characterize the extended, isotropic micellar solution phase in the binary phase diagram of choline octanoate viscosity and conductivity measurements were also carried out.

Mitigation of the inhibitory effect of soap by magnesium salt treatment of crude glycerol--a novel approach for enhanced biohydrogen production from the biodiesel industry waste.

PubMed

Sarma, Saurabh Jyoti; Brar, Satinder Kaur; Le Bihan, Yann; Buelna, Gerardo; Soccol, Carlos Ricardo

2014-01-01

Owing to its inhibitory effect on microbial growth, soap present in crude glycerol (CG) is a concern in biological valorization of the biodiesel manufacturing waste. By salting out strategy, up to 42% of the soap has been removed and the approach has beneficial effect on H2 production; however, removal of more than 7% of the soap was found to be inhibitory. Actually, soap is utilized as a co-substrate and due to removal; the carbon-nitrogen ratio of the medium might have decreased to reduce the production. Alternatively, without changing the carbon-nitrogen ratio of CG, MgSO4 treatment can convert the soap to its inactive form (scum). The approach was found to increase the H2 production rate (33.82%), cumulative H2 production (34.70%) as well as glycerol utilization (nearly 2.5-folds). Additionally, the treatment can increase the Mg (a nutrient) content of the medium from 0.57 ppm to 201.92 ppm. Copyright © 2013 Elsevier Ltd. All rights reserved.

Stool fatty acid soaps, stool consistency and gastrointestinal tolerance in term infants fed infant formulas containing high sn-2 palmitate with or without oligofructose: a double-blind, randomized clinical trial.

PubMed

Nowacki, Joyce; Lee, Hung-Chang; Lien, Reyin; Cheng, Shao-Wen; Li, Sung-Tse; Yao, Manjiang; Northington, Robert; Jan, Ingrid; Mutungi, Gisella

2014-11-05

Formula-fed (FF) infants often have harder stools and higher stool concentrations of fatty acid soaps compared to breastfed infants. Feeding high sn-2 palmitate or the prebiotic oligofructose (OF) may soften stools, reduce stool soaps, and decrease fecal calcium loss. We investigated the effect of high sn-2 palmitate alone and in combination with OF on stool palmitate soap, total soap and calcium concentrations, stool consistency, gastrointestinal (GI) tolerance, anthropometrics, and hydration in FF infants. This double-blind trial randomized 165 healthy term infants 25-45 days old to receive Control formula (n = 54), formula containing high sn-2 palmitate (sn-2; n = 56), or formula containing high sn-2 palmitate plus 3 g/L OF (sn-2+OF; n = 55). A non-randomized human milk (HM)-fed group was also included (n = 55). The primary endpoint, stool composition, was determined after 28 days of feeding, and was assessed using ANOVA accompanied by pairwise comparisons. Stool consistency, GI tolerance and hydration were assessed at baseline, day 14 (GI tolerance only) and day 28. Infants fed sn-2 had lower stool palmitate soaps compared to Control (P = 0.0028); while those fed sn-2+OF had reduced stool palmitate soaps compared to both Control and sn-2 (both P < 0.0001). Stool total soaps and calcium were lower in the sn-2+OF group than either Control (P < 0.0001) or sn-2 (P < 0.0001). The HM-fed group had lower stool palmitate soaps, total soaps and calcium (P < 0.0001 for each comparison) than all FF groups. The stool consistency score of the sn-2+OF group was lower than Control and sn-2 (P < 0.0001), but higher than the HM-fed group (P < 0.0001). GI tolerance was similar and anthropometric z-scores were <0.2 SD from the WHO growth standards in all groups, while urinary hydration markers were within normal range for all FF infants. Increasing sn-2 palmitate in infant formula reduces stool palmitate soaps. A combination of high sn-2 palmitate and OF reduces

The sensitivity and clinical course of patients with wheat-dependent exercise-induced anaphylaxis sensitized to hydrolyzed wheat protein in facial soap - secondary publication.

PubMed

Hiragun, Makiko; Ishii, Kaori; Hiragun, Takaaki; Shindo, Hajime; Mihara, Shoji; Matsuo, Hiroaki; Hide, Michihiro

2013-09-01

Recently, an increasing number of patients with wheat-dependent exercise-induced anaphylaxis (WDEIA) have been reported in Japan. Most of them had developed this condition during or after using hydrolyzed wheat protein (HWP)-containing soap (HWP-WDEIA). To clarify the relation between WDEIA and HWP-containing soap and their prognosis, we retrospectively studied the patients who visited Hiroshima University Hospital and were diagnosed as WDEIA from January 2010 to June 2011. We took detailed clinical histories, performed skin prick tests, serum immunoassays for antigen-specific IgE and basophil histamine release test, and followed up their clinical courses after the diagnosis. Among 36 patients with WDEIA, 30 patients had used only one type of HWP-soap. The patients with HWP-WDEIA were mainly women and had developed facial symptoms and angioedema. They suffered from blood pressure reductions less frequently than patients with conventional WDEIA. The levels of gluten-specific IgE were higher than those of omega-5 gliadin in patients with HWP-WDEIA (P < 0.05, One-way ANOVA). All patients with HWP-WDEIA were positive against HWP in histamine release test. Among the conventional wheat antigens, glutenins induced the highest histamine release from basophils of patients with HWP-WDEIA. The sensitivities of patients against glutens and glutenins were reduced over months along with the discontinuance of HWP-soap. The development of HWP-WDEIA is associated with the use of HWP-soap. The sensitivity to HWP that cross reacts with non-processed wheat may be reduced or possibly cured after the discontinuation of HWP-soap.

Entertainment Education and Social Change: Evaluating a Children's Soap Opera in Kenya

ERIC Educational Resources Information Center

de Block, Liesbeth

2012-01-01

This article discusses audience responses to a children's soap opera produced and broadcast in Kenya. It examines the evaluation process in relation to qualitative audience research within Cultural Studies. It challenges an Entertainment-Education model of media as vehicles for messages and links strongly with Communication for Social Change…

Effect of soaps and detergents on epidermal barrier function.

PubMed

Wolf, Ronni; Parish, Lawrence Charles

2012-01-01

The past decade has witnessed an explosion of new impartial information about the complex interaction of the skin with topically applied substances, including soaps and detergents. Despite of all these new data, our knowledge on the exact pathomechanism and molecular events leading to detergent-induced barrier dysfunction remains incomplete and the answers continue to elude us. The longtime prevailing opinion which contends that the damaging effect of soaps and detergents is related to their property to extract and remove useful intercellular lipids has mostly been abandoned. Although this effect might be involved in the damaging effect, it is definitely not the sole mechanism, nor, indeed, is it even the main one. Skin proteins damage, the interaction with keratins and their denaturation, swelling of cell membranes and collagen fibers, cytotoxicity expressed with cellular lysis are other important mechanisms. One proposed mechanism is that an initial stratum corneum hyper-hydration results from a continuous disruption of the secondary and tertiary structures of keratin protein by surfactants, exposing new water-binding sites, thereby increasing the hydration of the membrane. Following evaporation of excess water, the denatured keratin possesses a decreased water-binding capacity and decreased ability to function as a barrier. Recent studies have also emphasized the effects of detergents on lipid synthesis, on lipid-metabolizing enzymes and on keratinocyte differentiation. Copyright © 2012 Elsevier Inc. All rights reserved.

An analogue conceptual rainfall-runoff model for educational purposes

NASA Astrophysics Data System (ADS)

Herrnegger, Mathew; Riedl, Michael; Schulz, Karsten

2016-04-01

Conceptual rainfall-runoff models, in which runoff processes are modelled with a series of connected linear and non-linear reservoirs, remain widely applied tools in science and practice. Additionally, the concept is appreciated in teaching due to its somewhat simplicity in explaining and exploring hydrological processes of catchments. However, when a series of reservoirs are used, the model system becomes highly parametrized and complex and the traceability of the model results becomes more difficult to explain to an audience not accustomed to numerical modelling. Since normally the simulations are performed with a not visible digital code, the results are also not easily comprehensible. This contribution therefore presents a liquid analogue model, in which a conceptual rainfall-runoff model is reproduced by a physical model. This consists of different acrylic glass containers representing different storage components within a catchment, e.g. soil water or groundwater storage. The containers are equipped and connected with pipes, in which water movement represents different flow processes, e.g. surface runoff, percolation or base flow. Water from a storage container is pumped to the upper part of the model and represents effective rainfall input. The water then flows by gravity through the different pipes and storages. Valves are used for controlling the flows within the analogue model, comparable to the parameterization procedure in numerical models. Additionally, an inexpensive microcontroller-based board and sensors are used to measure storage water levels, with online visualization of the states as time series data, building a bridge between the analogue and digital world. The ability to physically witness the different flows and water levels in the storages makes the analogue model attractive to the audience. Hands-on experiments can be performed with students, in which different scenarios or catchment types can be simulated, not only with the analogue but

Influence of boundary conditions on the existence and stability of minimal surfaces of revolution made of soap films

NASA Astrophysics Data System (ADS)

Salkin, Louis; Schmit, Alexandre; Panizza, Pascal; Courbin, Laurent

2014-09-01

Because of surface tension, soap films seek the shape that minimizes their surface energy and thus their surface area. This mathematical postulate allows one to predict the existence and stability of simple minimal surfaces. After briefly recalling classical results obtained in the case of symmetric catenoids that span two circular rings with the same radius, we discuss the role of boundary conditions on such shapes, working with two rings having different radii. We then investigate the conditions of existence and stability of other shapes that include two portions of catenoids connected by a planar soap film and half-symmetric catenoids for which we introduce a method of observation. We report a variety of experimental results including metastability—an hysteretic evolution of the shape taken by a soap film—explained using simple physical arguments. Working by analogy with the theory of phase transitions, we conclude by discussing universal behaviors of the studied minimal surfaces in the vicinity of their existence thresholds.

Efficacy of Waterless Hand Hygiene Compared with Handwashing with Soap: A Field Study in Dar es Salaam, Tanzania

PubMed Central

Pickering, Amy J.; Boehm, Alexandria B.; Mwanjali, Mathew; Davis, Jennifer

2010-01-01

Effective handwashing with soap requires reliable access to water supplies. However, more than three billion persons do not have household-level access to piped water. This research addresses the challenge of improving hand hygiene within water-constrained environments. The antimicrobial efficacy of alcohol-based hand sanitizer, a waterless hand hygiene product, was evaluated and compared with handwashing with soap and water in field conditions in Dar es Salaam, Tanzania. Hand sanitizer use by mothers resulted in 0.66 and 0.64 log reductions per hand of Escherichia coli and fecal streptococci, respectively. In comparison, handwashing with soap resulted in 0.50 and 0.25 log reductions per hand of E. coli and fecal streptococci, respectively. Hand sanitizer was significantly better than handwashing with respect to reduction in levels of fecal streptococci (P = 0.01). The feasibility and health impacts of promoting hand sanitizer as an alternative hand hygiene option for water-constrained environments should be assessed. PMID:20134005

Surgical hand antisepsis in veterinary practice: evaluation of soap scrubs and alcohol based rub techniques.

PubMed

Verwilghen, Denis R; Mainil, Jacques; Mastrocicco, Emilie; Hamaide, Annick; Detilleux, Johann; van Galen, Gaby; Serteyn, Didier; Grulke, Sigrid

2011-12-01

Recent studies have shown that hydro-alcoholic solutions are more efficient than traditional medicated soaps in the pre-surgical hand antisepsis of human surgeons but there is little veterinary literature on the subject. The aim of this study was to compare the efficiency of medicated soaps and a hydro-alcoholic solution prior to surgery using an in-use testing method in a veterinary setting. A preliminary trial was performed that compared the mean log(10) number of bacterial colony forming units (CFU) and the reduction factors (RF) between two 5-min hand-scrubbing sessions using different soaps, namely, povidone iodine (PVP) and chlorhexidine gluconate (CHX), and the 1.5-min application of a hydro-alcoholic rub. A clinical in-use trial was then used to compare the hydro-alcoholic rub and CHX in a surgical setting. Sampling was performed using finger printing on agar plates. The hydro-alcoholic rub and CHX had a similar immediate effect, although the sustained effect was significantly better for the hydro-alcoholic rub, while PVP had a significantly lower immediate and sustained effect. The hydro-alcoholic rub showed good efficiency in the clinical trial and could be considered as a useful alternative method for veterinary surgical hand antisepsis. Copyright © 2010 Elsevier Ltd. All rights reserved.

Thin film instabilities: Rayleigh-Taylor with thermocapillarity and Kolmogorov flow in a soap film

NASA Astrophysics Data System (ADS)

Burgess, John Matthew

The Rayleigh-Taylor instability occurs when a more dense fluid layer is suspended above a less dense fluid layer in a gravitational field. The horizontal interface between the two fluids is unstable to infinitesimal deformations and the dense fluid falls. To counteract the destabilizing effects of gravity on the interface between two thin fluid layers, we apply a vertical temperature gradient, heating from below. The dependence of surface tension on temperature (``thermocapillarity'') can cause spatially-varying interfacial forces between two immiscible fluid layers if a variation in temperature along the interface is introduced. With an applied vertical temperature gradient, the deforming interface spontaneously develops temperature variations which locally adjust the surface tension to restore a flat interface. We find that these surface tension gradients can stabilize a more dense thin fluid layer (silicone oil, 0.015 cm thick) above a less dense thin fluid layer (air, 0.025 cm thick) in a gravitational field, in qualitative agreement with linear stability analysis. This is the first experimental observation of the stabilization of Rayleigh-Taylor instability by thermocapillary forces. We also examine the instability of a soap film flow driven by a time-independent force that is spatially periodic in the direction perpendicular to the forcing (Kolmogorov flow). The film is in the x- y plane, where the forcing approximates a shape sin (y)x̂. Linear stability analysis of an idealized model of this flow predicts a critical Reynolds number Rc~2 . In our soap film experiment, we find a critical value Rc~70 . This discrepancy can be ascribed to frictional effects from viscous coupling of gas to the film, which is neglected in the idealized model. The kinematic viscosity of the surrounding gas and the thickness of gas layers on each side of the soap film are varied in the experiments to better understand these frictional effects. We conclude that

Effect of a behaviour-change intervention on handwashing with soap in India (SuperAmma): a cluster-randomised trial.

PubMed

Biran, Adam; Schmidt, Wolf-Peter; Varadharajan, Kiruba Sankar; Rajaraman, Divya; Kumar, Raja; Greenland, Katie; Gopalan, Balaji; Aunger, Robert; Curtis, Val

2014-03-01

Diarrhoea and respiratory infections are the two biggest causes of child death globally. Handwashing with soap could substantially reduce diarrhoea and respiratory infections, but prevalence of adequate handwashing is low. We tested whether a scalable village-level intervention based on emotional drivers of behaviour, rather than knowledge, could improve handwashing behaviour in rural India. The study was done in Chittoor district in southern Andhra Pradesh, India, between May 24, 2011, and Sept 10, 2012. Eligible villages had a population of 700-2000 people, a state-run primary school for children aged 8-13 years, and a preschool for children younger than 5 years. 14 villages (clusters) were selected, stratified by population size (<1200 vs >1200), and randomly assigned in a 1:1 ratio to intervention or control (no intervention). Clusters were enrolled by the study manager. Random allocation was done by the study statistician using a random number generator. The intervention included community and school-based events incorporating an animated film, skits, and public pledging ceremonies. Outcomes were measured by direct observation in 20-25 households per village at baseline and at three follow-up visits (6 weeks, 6 months, and 12 months after the intervention). Observers had no connection with the intervention and observers and participant households were told that the study was about domestic water use to reduce the risk of bias. No other masking was possible. The primary outcome was the proportion of handwashing with soap at key events (after defecation, after cleaning a child's bottom, before food preparation, and before eating) at all follow-up visits. The control villages received a shortened version of the intervention before the final follow-up round. Outcome data are presented as village-level means. Handwashing with soap at key events was rare at baseline in both the intervention and control groups (1% [SD 1] vs 2% [1]). At 6 weeks' follow-up, handwashing

Statistical analogues of thermodynamic extremum principles

NASA Astrophysics Data System (ADS)

Ramshaw, John D.

2018-05-01

As shown by Jaynes, the canonical and grand canonical probability distributions of equilibrium statistical mechanics can be simply derived from the principle of maximum entropy, in which the statistical entropy S=- {k}{{B}}{\\sum }i{p}i{log}{p}i is maximised subject to constraints on the mean values of the energy E and/or number of particles N in a system of fixed volume V. The Lagrange multipliers associated with those constraints are then found to be simply related to the temperature T and chemical potential μ. Here we show that the constrained maximisation of S is equivalent to, and can therefore be replaced by, the essentially unconstrained minimisation of the obvious statistical analogues of the Helmholtz free energy F = E ‑ TS and the grand potential J = F ‑ μN. Those minimisations are more easily performed than the maximisation of S because they formally eliminate the constraints on the mean values of E and N and their associated Lagrange multipliers. This procedure significantly simplifies the derivation of the canonical and grand canonical probability distributions, and shows that the well known extremum principles for the various thermodynamic potentials possess natural statistical analogues which are equivalent to the constrained maximisation of S.

Can Cultural Competence Be Taught? Evaluating the Impact of the SOAP Model

ERIC Educational Resources Information Center

Colvin-Burque, Angie; Zugazaga, Carole B.; Davis-Maye, Denise

2007-01-01

This article discusses the Self and Other Awareness Project (SOAP) cultural competence development model and presents the results of a study that evaluated its impact on the racial attitudes of 110 undergraduate students enrolled in an undergraduate interdisciplinary Minority Groups course at a mid-sized public university in the Southeastern…

Large seismic source imaging from old analogue seismograms

NASA Astrophysics Data System (ADS)

Caldeira, Bento; Buforn, Elisa; Borges, José; Bezzeghoud, Mourad

2017-04-01

In this work we present a procedure to recover the ground motions by a proper digital structure, from old seismograms in analogue physical support (paper or microfilm) to study the source rupture process, by application of modern finite source inversion tools. Despite the quality that the analog data and the digitizing technologies available may have, recover the ground motions with the accurate metrics from old seismograms, is often an intricate procedure. Frequently the general parameters of the analogue instruments response that allow recover the shape of the ground motions (free periods and damping) are known, but the magnification that allow recover the metric of these motions is dubious. It is in these situations that the procedure applies. The procedure is based on assign of the moment magnitude value to the integral of the apparent Source Time Function (STF), estimated by deconvolution of a synthetic elementary seismogram from the related observed seismogram, corrected with an instrument response affected by improper magnification. Two delicate issues in the process are 1) the calculus of the synthetic elementary seismograms that must consider later phases if applied to large earthquakes (the portions of signal should be 3 or 4 times larger than the rupture time) and 2) the deconvolution to calculate the apparent STF. In present version of the procedure was used the Direct Solution Method to compute the elementary seismograms and the deconvolution was processed in time domain by an iterative algorithm that allow constrains the STF to stay positive and time limited. The method was examined using synthetic data to test the accuracy and robustness. Finally, a set of 17 real old analog seismograms from the Santa Maria (Azores) 1939 earthquake (Mw=7.1) was used in order to recover the waveforms in the required digital structure, from which by inversion allows compute the finite source rupture model (slip distribution). Acknowledgements: This work is co

The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively.

PubMed

Nicander, Ingrid; Aberg, Peter; Ollmar, Stig

2003-02-01

Products containing detergents can damage the skin and give rise to irritant contact dermatitis. Therefore, attempts have been made to find less irritating detergents as well as substances decreasing undesired side-effects of detergents, and a novel approach is offered by betaine. The aim of the study has been to determine the irritating properties of some liquid soaps for personal hygiene and to map the effect of different concentrations of betaine using electrical impedance, trans-epidermal water loss and visual inspection. Twenty-eight healthy subjects were patch tested with different commercial soaps with and without betaine and sodium lauryl sulphate on both volar forearms for 24 h. A site with distilled water and an unoccluded area were used as references. Responses of the skin reactions were evaluated by visual inspection and by measuring trans-epidermal water loss and electrical impedance before application and 24 h after removal of the chambers. Significant skin reactions were found for all soaps tested but the soaps containing betaine were the least irritating. However, the skin irritation did not decrease with increasing concentrations of betaine in the tested range. On the whole the differences between the products were not large. The non-invasive methods used were more sensitive than visual assessment for evaluation of invisible or barely visible skin responses. Copyright Blackwell Munksgaard 2003

Study on small molecular organic compounds pyrolysed from rubber seed oil and its sodium soap.

PubMed

Fernando, T L D; Prashantha, M A B; Amarasinghe, A D U S

2016-01-01

Rubber seed oil (RSO) and its sodium soap were pyrolysed in a batch reactor to obtain low molar mass organic substances. The pyrolitic oil of RSO was redistilled and the distillates were characterized by GC-MS and FTIR. Density, acid value, saponification value and ester values were also measured according to the ASTM standard methods. A similar analysis was done for samples taken out at different time intervals from the reaction mixture. Industrially important low molar mass alkanes, alkenes, aromatics, cyclic compounds and carboxylic acids were identified in the pyrolysis process of rubber seed oil. However, pyrolysis of the sodium soap of rubber seed oil gave a mixture of hydrocarbons in the range of C14-C17 and hence it has more applications as a fuel.

The Application of Red Pigments from Streptomyces K-4B and Dayak Onions (Eleutherine palmifolia (L.) Merr.) In Colouring Glycerine Soap

NASA Astrophysics Data System (ADS)

Herlina; Asnani, A.; Diastuti, H.

2017-02-01

Glycerin soap has been colored with red pigment from Streptomyces K-4 B and Dayak onion (Eleutherine palmifolia (L.) Merr). Both red pigments from Streptomyces K-4B and Dayak onion were extracted with ethanol by maceration method, followed with soxhlet extraction. The concentration of red pigment added was varied (0, 200, 300, 400 μL) to evaluate the best product. The resulted glycerine soaps were characterized and analyzed based on SNI 06-3532-1994. The research results indicated that the glycerine soap has water content ranged from 0.36% to 12.56%; the amount of fatty acid ranged from 14% to 36.75%; the amount of free fatty acids ranged from 0% to 0.37%; the non-saponifiable fat ranged from 0.001 to 0.019%; the pH ranged from 10.33 to 11.06; the foam stability ranged from 0.61% to 89.09%. The results of analysis of variance showed that the effect between treatments significantly different at 95% confidence level (α = 0.05) on the characteristics of glycerine soap. The results of an organoleptic test with parameters observed were color, aroma, texture, foam, rough impression upon usage and rough impression after usage, gave “like to very like soap” with a maximum score of 4.67 (1 to 5 scale). Based on the color assessment, the organoleptic panelists preferred the glycerine soap of SK-4B3 (red pigment from Streptomyces K-4B, 200 μL) with the score of 4.30 (like to very like).

[Wheat anaphylaxis or wheat-dependent exercise-induced anaphylaxis caused by use of a soap product which contains hydrolyzed wheat proteins. -a report of 12 cases-].

PubMed

Sugiyama, Akiko; Kishikawa, Reiko; Nishie, Haruko; Takeuchi, Satoshi; Shimoda, Terufumi; Iwanaga, Tomoaki; Nishima, Sankei; Furue, Masutaka

2011-11-01

Recently, it has become a social problem that hydrolyzed wheat protein in facial soap can induce wheat allergy including wheat-dependent exercise-induced anaphylaxis (WDEIA). We described the clinical characteristics of the patients related. We collected 12 cases who had had a medical examination from January to October in 2010. All the patients were female and mean age was 36.0± 9.9 years. All of them had had no prior symptoms history of wheat allergy, they gradually developed wheat anaphylaxis or WDEIA in an average of 2 years after they started to use a soap product in question which contains hydrolyzed wheat proteins. Most patients suffered immediate contact allergic reactions after or at the time of washing their face with the soap product. 10 of 12 patients showed a low level of IgE to CAP-recombinant ω-5-gliadin. Episodes of anaphylaxis were prevented by avoiding both intake of wheat-containing foods and usage of the soap product. We concluded that their wheat anaphylaxis is likely to be caused by epicutaneous sensitization of the hydrolyzed wheat proteins in the soap product. It was important that physicians should know the possibility of sensitization from non-dietary antigen.

Keeping Up with the Joneses. A Soap Opera for Adult ESL Students.

ERIC Educational Resources Information Center

Phillips, Chiquita

A series of high-interest, low English-language-learning-level stories developed for adult students of English as a second language are combined as a soap opera for classroom use. An introductory section outlines techniques for presentation of the texts on tape and in written form and for exercises in listening, making inferences, reading, and…

Analysis of the effectiveness of different hygiene procedures used in dental prostheses.

PubMed

Rossato, Marisa Bagiotto; Unfer, Beatriz; May, Lilana Gressler; Braun, Katia Olmedo

2011-01-01

To compare the effectiveness of bacterial plaque removal of six denture hygiene procedures used by patients to clean their dentures. Fifteen students randomly divided into groups G1, G2, G3, G4, G5 and G6 used maxillary intraoral appliances for 24 h without cleaning them. Afterwards, the appliances were submitted to the following procedures: P1: washing under running water for 20 s; P2 and P3: cleaning with alkaline peroxide (Corega Tabs®) for 5 and 30 min, respectively; P4: brushing with water and liquid soap for 40 s; P5: alkaline hypochlorite for 10 minutes; P6: home use chlorine solution (Q'boa® at 0.45% for 10 min), throughout a period of 6 consecutive weeks. The procedures followed a circulating scheme, so that all the appliances were submitted to all the hygiene methods studied. After the hygiene procedures, the appliances were stained, photographed and submitted to the weighing method. After ANOVA and Tukey's test, differences were observed: P5 = 0.73 ± 0.3 (b), P6 = 1.27 ± 0.4(b,c), P4 = 1.92 ± 0.5 (b,c), P3 = 2.24 ± 1.0 (b,c), P2 = 7.53 ± 2.5 (c) and P1 = 26.86 ± 15. 3 (a). From the results of the study, it could be concluded that the use of alkaline hypochlorite is the best way to remove bacterial plaque, followed by the home-use chlorine solution and brushing with water and liquid soap. Corega Tabs® must be used for 30 min of immersion to have a cleaning effectiveness similar to that of alkaline hypochlorite.

Current european regulatory perspectives on insulin analogues.

PubMed

Enzmann, Harald G; Weise, Martina

2011-07-07

Insulin analogues are increasingly considered as an alternative to human insulin in the therapy of diabetes mellitus. Insulin analogues (IAs) are chemically different from human insulin and may have different pharmacokinetic or pharmacodynamic properties. The significance of the modifications of the insulin molecule for the safety profile of IAs must be considered. This review describes the regulatory procedure and the expectations for the scientific content of European marketing authorization applications for innovative IAs submitted to the European Medicines Agency. Particular consideration is given to a potential cancer hazard. Specific regulatory guidance on how to address a possible carcinogenic or tumor promoting effect of innovative IAs in non-clinical studies is available. After marketing authorization, the factual access of patients to the new product will be determined to great extent by health technology assessment bodies, reimbursement decisions and the price. Whereas the marketing authorization is a European decision, pricing and reimbursement are national or regional responsibilities. The assessment of benefit and risk by the European Medicines Agency is expected to influence future decisions on price and reimbursement on a national or regional level. Collaborations between regulatory agencies and health technology assessment bodies have been initiated on European and national level to facilitate the use of the European Medicines Agency's benefit risk assessment as basis on which to build the subsequent health technology assessment. The option for combined or joint scientific advice procedures with regulators and health technology assessment bodies on European level or on a national level in several European Member States may help applicants to optimize their development program and dossier preparation in regard of both European marketing authorization application and reimbursement decisions.

Soap films burst like flapping flags.

PubMed

Lhuissier, Henri; Villermaux, Emmanuel

2009-07-31

When punctured, a flat soap film bursts by opening a hole driven by liquid surface tension. The hole rim does not, however, remain smooth but soon develops indentations at the tip of which ligaments form, ultimately breaking and leaving the initially connex film into a mist of disjointed drops. We report on original observations showing that these indentations result from a flaglike instability between the film and the surrounding atmosphere inducing an oscillatory motion out of its plane. Just like a flag edge flaps in the wind, the film is successively accelerated on both sides perpendicularly to its plane, inducing film thickness modulations and centrifuging liquid ligaments that finally pinch off to form the observed spray. This effect exemplifies how the dynamics of fragile objects such as thin liquid films is sensitive to their embedding medium.

SOAP-T: a tool to study the light curve and radial velocity of a system with a transiting planet and a rotating spotted star

NASA Astrophysics Data System (ADS)

Oshagh, M.; Boisse, I.; Boué, G.; Montalto, M.; Santos, N. C.; Bonfils, X.; Haghighipour, N.

2013-01-01

We present an improved version of SOAP named "SOAP-T", which can generate the radial velocity variations and light curves for systems consisting of a rotating spotted star with a transiting planet. This tool can be used to study the anomalies inside transit light curves and the Rossiter-McLaughlin effect, to better constrain the orbital configuration and properties of planetary systems and the active zones of their host stars. Tests of the code are presented to illustrate its performance and to validate its capability when compared with analytical models and real data. Finally, we apply SOAP-T to the active star, HAT-P-11, observed by the NASA Kepler space telescope and use this system to discuss the capability of this tool in analyzing light curves for the cases where the transiting planet overlaps with the star's spots. The tool's public interface is available at http://www.astro.up.pt/resources/soap-t/

Sulfur-Oxidizing Bacteria in Soap Lake (Washington State), a Meromictic, Haloalkaline Lake with an Unprecedented High Sulfide Content▿

PubMed Central

Sorokin, Dimitry Y.; Foti, Mirjam; Pinkart, Holly C.; Muyzer, Gerard

2007-01-01

Culture-dependent and -independent techniques were used to study the diversity of chemolithoautotrophic sulfur-oxidizing bacteria in Soap Lake (Washington State), a meromictic, haloalkaline lake containing an unprecedentedly high sulfide concentration in the anoxic monimolimnion. Both approaches revealed the dominance of bacteria belonging to the genus Thioalkalimicrobium, which are common inhabitants of soda lakes. A dense population of Thioalkalimicrobium (up to 107 cells/ml) was found at the chemocline, which is characterized by a steep oxygen-sulfide gradient. Twelve Thioalkalimicrobium strains exhibiting three different phenotypes were isolated in pure culture from various locations in Soap Lake. The isolates fell into two groups according to 16S rRNA gene sequence analysis. One of the groups was closely related to T. cyclicum, which was isolated from Mono Lake (California), a transiently meromictic, haloalkaline lake. The second group, consisting of four isolates, was phylogenetically and phenotypically distinct from known Thioalkalimicrobium species and unique to Soap Lake. It represented a new species, for which we suggest the name Thioalkalimicrobium microaerophilum sp. nov. PMID:17114324

Evaluation of human exposure to metals from some commonly used bathing soaps and shower gels in Nigeria.

PubMed

Iwegbue, Chukwujindu M A; Emakunu, Omotekoro S; Nwajei, Godwin E; Bassey, Francisca I; Martincigh, Bice S

2017-02-01

The concentrations of nine metals (Cd, Pb, Ni, Cr, Co, Cu, Fe, Mn and Zn) were measured in selected brands of medicated, moisturizing and skin-lightening soaps and shower gels with the aim of evaluating the human health risk associated with metal exposure from the use of these products. The concentrations of metals in these products were determined by means of atomic absorption spectrophotometry after sample digestion with a mixture of acids. The concentration ranges of the metals in the bathing soaps and shower gels were found to be: <0.06-3.4 μg g -1 for Cd, <0.09-26.5 μg g -1 for Pb, <0.12-43.0 μg g -1 for Cr, <0.06-32.5 μg g -1 for Ni, <0.06-40.5 μg g -1 for Cu, <0.12-8.0 μg g -1 for Co, 61.8-4000 μg g -1 for Fe, <0.09-29.5 μg g -1 for Mn, and 25.5-1000 μg g -1 for Zn. The systemic exposure dosage values for these metals obtained from the application of these brands of bathing soaps and shower gels were below their respective provisional tolerable daily intake/or recommended daily intake values. The margin of safety values obtained for the metals were greater than 100 which indicated that there was no significant risk to the users of these brands of bathing soaps and shower gels, except in the case of Co. Copyright © 2016 Elsevier Inc. All rights reserved.

Effect of calcium soaps of fatty acids and administration of somatotropin in early lactation on productive and reproductive performance of high producing dairy cows.

PubMed

Moallem, U; Kaim, M; Folman, Y; Sklan, D

1997-09-01

This study examined the mechanisms by which calcium soaps of fatty acids and bovine somatotropin (bST) affect production and reproduction of high producing cows. Calcium soaps of fatty acids were fed at 2.2% dry matter, and 500 mg of Zn-sometribove (Monsanto Inc., St Louis, MO) were injected subcutaneously every 14 d from 10 to 150 d in milk (DIM). Production of fat-corrected milk was increased by 3.5 kg/d when calcium soaps of fatty acids were fed, by 6.1 kg/d when bST was administered, and by 7.4 kg/d when calcium soaps of fatty acids were fed and bST was administered. Body weight was similar for cows on all treatments until 85 DIM after which cows that were treated with bST had lower body weights. Body condition scores decreased more for cows treated with bST and began increasing later and more slowly. Treatment with bST resulted in more cows that experienced first ovulation after 30 DIM, and more cows on the control treatment exhibited first estrus before 35 DIM. Days open were greater when bST was administered. After the first artificial insemination, conception rates were similar for cows on the control treatment and for cows fed calcium soaps of fatty acids; conception rates after the first artificial insemination were low for all cows treated with bST. Pregnancy rates at 120 and 150 DIM were decreased by bST. Number of DIM to first ovulation, number of DIM to first estrus, and days open were negatively correlated with glucose and cholesterol concentrations in plasma. Production of fat-corrected milk was correlated with days open and with concentrations of triglycerides in plasma, nonesterified fatty acids, and cholesterol. Increased production had different effects on reproduction when induced by calcium soaps of fatty acids or bST treatment. Some of the adverse effects of bST treatments were alleviated by calcium soaps of fatty acids.

Giant optical activity of sugar in thin soap films.

PubMed

Emile, Janine; Emile, Olivier; Ghoufi, Aziz; Moréac, Alain; Casanova, Federico; Ding, Minxia; Houizot, Patrick

2013-10-15

We report on enhanced experimental optical activity measurements of thin soap films in the presence of sugar. This unusual optical activity is linked to the intramolecular chiral conformation of the glucose molecules at the air/liquid interface. Choosing sodium dodecylsulfate (SDS) as a model surfactant and glucose as model sugar, favorable interactions between the anionic group -OSO3(-)- and the glucose molecules are highlighted. This induces an interfacial anchoring of glucose molecules leading to a perturbing influence of the asymmetric chiral environment. Copyright © 2013 Elsevier Inc. All rights reserved.

Moviemaking for the Language Acquisition Classroom: Engage Your Students with an Instructional "Soap"

ERIC Educational Resources Information Center

Carlson, Gigi; Crowther, Judith

2004-01-01

Television melodrama, like grand opera, is constructed to formula. Character interactions are highly charged and plot dominates, initiating excitement, suspense, and raising questions around timeless and universal themes. Despite--or because of--their extreme nature, the soaps remain one of the longest-standing television genres, with the loyal…

Measuring and overcoming limits of the Saffman-Delbrück model for soap film viscosities.

PubMed

Vivek, Skanda; Weeks, Eric R

2015-01-01

We observe tracer particles diffusing in soap films to measure the two-dimensional (2D) viscous properties of the films. Saffman-Delbrück type models relate the single-particle diffusivity to parameters of the film (such as thickness h) for thin films, but the relation breaks down for thicker films. Notably, the diffusivity is faster than expected for thicker films, with the crossover at h/d = 5.2 ± 0.9 using the tracer particle diameter d. This indicates a crossover from purely 2D diffusion to diffusion that is more three-dimensional. We demonstrate that measuring the correlations of particle pairs as a function of their separation overcomes the limitations of the Saffman-Delbrück model and allows one to measure the viscosity of a soap film for any thickness.

Measuring and Overcoming Limits of the Saffman-Delbrück Model for Soap Film Viscosities

PubMed Central

Vivek, Skanda; Weeks, Eric R.

2015-01-01

We observe tracer particles diffusing in soap films to measure the two-dimensional (2D) viscous properties of the films. Saffman-Delbrück type models relate the single-particle diffusivity to parameters of the film (such as thickness h) for thin films, but the relation breaks down for thicker films. Notably, the diffusivity is faster than expected for thicker films, with the crossover at h/d = 5.2 ± 0.9 using the tracer particle diameter d. This indicates a crossover from purely 2D diffusion to diffusion that is more three-dimensional. We demonstrate that measuring the correlations of particle pairs as a function of their separation overcomes the limitations of the Saffman-Delbrück model and allows one to measure the viscosity of a soap film for any thickness. PMID:25822262

A computational approach for predicting off-target toxicity of antiviral ribonucleoside analogues to mitochondrial RNA polymerase.

PubMed

Freedman, Holly; Winter, Philip; Tuszynski, Jack; Tyrrell, D Lorne; Houghton, Michael

2018-06-22

In the development of antiviral drugs that target viral RNA-dependent RNA polymerases, off-target toxicity caused by the inhibition of the human mitochondrial RNA polymerase (POLRMT) is a major liability. Therefore, it is essential that all new ribonucleoside analogue drugs be accurately screened for POLRMT inhibition. A computational tool that can accurately predict NTP binding to POLRMT could assist in evaluating any potential toxicity and in designing possible salvaging strategies. Using the available crystal structure of POLRMT bound to an RNA transcript, here we created a model of POLRMT with an NTP molecule bound in the active site. Furthermore, we implemented a computational screening procedure that determines the relative binding free energy of an NTP analogue to POLRMT by free energy perturbation (FEP), i.e. a simulation in which the natural NTP molecule is slowly transformed into the analogue and back. In each direction, the transformation was performed over 40 ns of simulation on our IBM Blue Gene Q supercomputer. This procedure was validated across a panel of drugs for which experimental dissociation constants were available, showing that NTP relative binding free energies could be predicted to within 0.97 kcal/mol of the experimental values on average. These results demonstrate for the first time that free-energy simulation can be a useful tool for predicting binding affinities of NTP analogues to a polymerase. We expect that our model, together with similar models of viral polymerases, will be very useful in the screening and future design of NTP inhibitors of viral polymerases that have no mitochondrial toxicity. © 2018 Freedman et al.

Hand washing with soap and water together with behavioural recommendations prevents infections in common work environment: an open cluster-randomized trial.

PubMed

Savolainen-Kopra, Carita; Haapakoski, Jaason; Peltola, Piia A; Ziegler, Thedi; Korpela, Terttu; Anttila, Pirjo; Amiryousefi, Ali; Huovinen, Pentti; Huvinen, Markku; Noronen, Heikki; Riikkala, Pia; Roivainen, Merja; Ruutu, Petri; Teirilä, Juha; Vartiainen, Erkki; Hovi, Tapani

2012-01-16

Hand hygiene is considered as an important means of infection control. We explored whether guided hand hygiene together with transmission-limiting behaviour reduces infection episodes and lost days of work in a common work environment in an open cluster-randomized 3-arm intervention trial. A total of 21 clusters (683 persons) were randomized to implement hand hygiene with soap and water (257 persons), with alcohol-based hand rub (202 persons), or to serve as a control (224 persons). Participants in both intervention arms also received standardized instructions on how to limit the transmission of infections. The intervention period (16 months) included the emergence of the 2009 influenza pandemic and the subsequent national hand hygiene campaign influencing also the control arm. In the total follow-up period there was a 6.7% reduction of infection episodes in the soap-and water arm (p = 0.04). Before the onset of the anti-pandemic campaign, a statistically significant (p = 0.002) difference in the mean occurrence of infection episodes was observed between the control (6.0 per year) and the soap-and-water arm (5.0 per year) but not between the control and the alcohol-rub arm (5.6 per year). Neither intervention had a decreasing effect on absence from work. We conclude that intensified hand hygiene using water and soap together with behavioural recommendations can reduce the occurrence of self-reported acute illnesses in common work environment. Surprisingly, the occurrence of reported sick leaves also increased in the soap-and water-arm. ClinicalTrials.gov: NCT00981877 The Finnish Work Environment Fund and the National Institute for Health and Welfare.

Helium-filled soap bubbles tracing fidelity in wall-bounded turbulence

NASA Astrophysics Data System (ADS)

Faleiros, David Engler; Tuinstra, Marthijn; Sciacchitano, Andrea; Scarano, Fulvio

2018-03-01

The use of helium-filled soap bubbles (HFSB) as flow tracers for particle image velocimetry (PIV) and particle tracking velocimetry (PTV) to measure the properties of turbulent boundary layers is investigated in the velocity range from 30 to 50 m/s. The experiments correspond to momentum thickness-based Reynolds numbers of 3300 and 5100. A single bubble generator delivers nearly neutrally buoyant HFSB to seed the air flow developing over the flat plate. The HFSB motion analysis is performed by PTV using single-frame multi-exposure recordings. The measurements yield the local velocity and turbulence statistics. Planar two-component-PIV measurements with micron-sized droplets (DEHS) conducted under the same conditions provide reference data for the quantities of interest. In addition, the behavior of air-filled soap bubbles is studied where the effect of non-neutral buoyancy is more pronounced. The mean velocity profiles as well as the turbulent stresses obtained with HFSB are in good agreement with the flow statistics obtained with DEHS particles. The study illustrates that HFSB tracers can be used to determine the mean velocity and the turbulent fluctuations of turbulent boundary layers above a distance of approximately two bubble diameters from the wall. This work broadens the current range of application of HFSB from external aerodynamics of large-scale-PIV experiments towards wall-bounded turbulence.

Effects of sunflower soap stocks on light lamb meat quality.

PubMed

Blanco, C; Giráldez, J F; Morán, L; Mateo, J; Villalobos-Delgado, L H; Andrés, S; Bodas, R

2017-08-01

Thirty-two lambs were used to study the effect of sunflower soap stocks (SS), a by-product from the vegetable oil refinery industry, on meat chemical composition, fatty acid profile, volatile compounds, and consumer acceptability. Lambs were finished (average length of fattening period 35 ± 7.3 d, 26.8 ± 0.09 kg final BW) on a pelleted total mixed ration (TMR) with no SS (00SS) or including 15, 30 or 60 g SS/kg (15SS, 30SS, and 60SS, respectively). Sunflower soap stocks decreased the percentage of SFA, increased the proportion of -MUFA ( < 0.05), and modified the levels of several odor-active lipid-derived volatile compounds ( 0.05). Consumers were able to distinguish between control and 15SS meat samples in a triangular test ( < 0.05), but a well-defined preference for meat of any of these treatments was not exhibited ( > 0.05). Atherogenicity and saturation indexes decreased by 31% and 27%, respectively, in SS groups compared to control (linear 0.05). However, certain volatile compounds (benzene and toluene) and 10-18:1 fatty acid, known potential hazards for human health, were increased in meat from lambs fed TMR with SS. For this reason, only inclusion rates up to 15 g SS/kg TMR seem to sustain a satisfactory balance between beneficial and detrimental effects on lamb meat composition and quality.

Optical Dust Characterization in Manned Mars Analogue Research Stations

NASA Technical Reports Server (NTRS)

Bos, B. J.; Krebs, Carolyn (Technical Monitor)

2003-01-01

Martian dust has been identified as a potentially serious hazard to any manned Mars landing mission. NASA and other organizations realize this risk and continue to support Martian dust research through the Matador project led by researchers at the University of Arizona. The Mars Society can contribute to this work by beginning a regimen of monitoring and measuring dust properties at its Mars analogue research stations. These research facilities offer the unique opportunity to study the transport and distribution of dust particles within a crewed habitat supporting active geologic exploration. Information regarding the amount, location and size of dust particles that may accumulate in a Mars habitat will be required to design a real Mars habitat and habitat equipment. Beginning such an effort does not require a large outlay of equipment and can be accomplished using crewmembers experienced with station operations. Various optical techniques, such as dark-field illumination, coupled with image processing algorithms enable the collection of dust grain relative size and frequency information. Such approaches can be applied in several different zones within the research stations to evaluate the various dust reduction and isolation procedures implemented during a particular crew rotation. As the stations simulation fidelity increases, the applicability of such data to a functional Mars lander will increase. This presentation describes the optical equipment and procedures for measuring dust properties in Mars analogue research stations that can be implemented during the next field season.

Quantitative Detection of Nucleoside Analogues by Multi-enzyme Biosensors using Time-Resolved Kinetic Measurements.

PubMed

Muthu, Pravin; Lutz, Stefan

2016-04-05

Fast, simple and cost-effective methods for detecting and quantifying pharmaceutical agents in patients are highly sought after to replace equipment and labor-intensive analytical procedures. The development of new diagnostic technology including portable detection devices also enables point-of-care by non-specialists in resource-limited environments. We have focused on the detection and dose monitoring of nucleoside analogues used in viral and cancer therapies. Using deoxyribonucleoside kinases (dNKs) as biosensors, our chemometric model compares observed time-resolved kinetics of unknown analytes to known substrate interactions across multiple enzymes. The resulting dataset can simultaneously identify and quantify multiple nucleosides and nucleoside analogues in complex sample mixtures. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Large scale particle image velocimetry with helium filled soap bubbles

NASA Astrophysics Data System (ADS)

Bosbach, Johannes; Kühn, Matthias; Wagner, Claus

2009-03-01

The application of Particle Image Velocimetry (PIV) to measurement of flows on large scales is a challenging necessity especially for the investigation of convective air flows. Combining helium filled soap bubbles as tracer particles with high power quality switched solid state lasers as light sources allows conducting PIV on scales of the order of several square meters. The technique was applied to mixed convection in a full scale double aisle aircraft cabin mock-up for validation of Computational Fluid Dynamics simulations.

Schlieren technique in soap film flows

NASA Astrophysics Data System (ADS)

Auliel, M. I.; Hebrero, F. Castro; Sosa, R.; Artana, G.

2017-05-01

We propose the use of the Schlieren technique as a tool to analyse the flows in soap film tunnels. The technique enables to visualize perturbations of the film produced by the interposition of an object in the flow. The variations of intensity of the image are produced as a consequence of the deviations of the light beam traversing the deformed surfaces of the film. The quality of the Schlieren image is compared to images produced by the conventional interferometric technique. The analysis of Schlieren images of a cylinder wake flow indicates that this technique enables an easy visualization of vortex centers. Post-processing of series of two successive images of a grid turbulent flow with a dense motion estimator is used to derive the velocity fields. The results obtained with this self-seeded flow show good agreement with the statistical properties of the 2D turbulent flows reported on the literature.

Changes in J-SOAP-II and SAVRY Scores Over the Course of Residential, Cognitive-Behavioral Treatment for Adolescent Sexual Offending

PubMed Central

Viljoen, Jodi L.; Gray, Andrew L.; Shaffer, Catherine; Latzman, Natasha E.; Scalora, Mario J.; Ullman, Daniel

2018-01-01

Although the Juvenile Sex Offender Assessment Protocol–II (J-SOAP-II) and the Structured Assessment of Violence Risk in Youth (SAVRY) include an emphasis on dynamic, or modifiable factors, there has been little research on dynamic changes on these tools. To help address this gap, we compared admission and discharge scores of 163 adolescents who attended a residential, cognitive-behavioral treatment program for sexual offending. Based on reliable change indices, one half of youth showed a reliable decrease on the J-SOAP-II Dynamic Risk Total Score and one third of youth showed a reliable decrease on the SAVRY Dynamic Risk Total Score. Contrary to expectations, decreases in risk factors and increases in protective factors did not predict reduced sexual, violent nonsexual, or any reoffending. In addition, no associations were found between scores on the Psychopathy Checklist:Youth Version and levels of change. Overall, the J-SOAP-II and the SAVRY hold promise in measuring change, but further research is needed. PMID:26199271

Changes in J-SOAP-II and SAVRY Scores Over the Course of Residential, Cognitive-Behavioral Treatment for Adolescent Sexual Offending.

PubMed

Viljoen, Jodi L; Gray, Andrew L; Shaffer, Catherine; Latzman, Natasha E; Scalora, Mario J; Ullman, Daniel

2017-06-01

Although the Juvenile Sex Offender Assessment Protocol-II (J-SOAP-II) and the Structured Assessment of Violence Risk in Youth (SAVRY) include an emphasis on dynamic, or modifiable factors, there has been little research on dynamic changes on these tools. To help address this gap, we compared admission and discharge scores of 163 adolescents who attended a residential, cognitive-behavioral treatment program for sexual offending. Based on reliable change indices, one half of youth showed a reliable decrease on the J-SOAP-II Dynamic Risk Total Score and one third of youth showed a reliable decrease on the SAVRY Dynamic Risk Total Score. Contrary to expectations, decreases in risk factors and increases in protective factors did not predict reduced sexual, violent nonsexual, or any reoffending. In addition, no associations were found between scores on the Psychopathy Checklist:Youth Version and levels of change. Overall, the J-SOAP-II and the SAVRY hold promise in measuring change, but further research is needed.

The irritation potential and reservoir effect of mild soaps.

PubMed

Lodén, Marie; Buraczewska, Izabela; Edlund, Fredrik

2003-08-01

Identification and reduction of external noxious factors is one key point in the strategy for the treatment and reduction of contact dermatitis. A wide variety of soaps on the market are claimed to be suitable for the use on sensitive skin due to their mildness. The aim of the present study was to illustrate possible differences in the irritation potential of 8 products and to investigate whether surfactant residues may form an irritant reservoir on the skin. The study was double-blind, randomized using healthy human volunteers. The inherent capacity of the products to induce irritation was determined using conventional patch test technique, whereas detection of potential surfactant residues on the skin was done using a methodology developed in the 1960s for detection of the corticosteroid reservoir in the stratum corneum. The method comprised the release of active substance from the stratum corneum reservoir by occlusion of the skin with an aluminium chamber, followed by evaluation of the biological response. In the present study, the soap-treated area was rinsed with water and then occluded. Instrumental measurements of the transepidermal water loss and superficial skin blood flow served as indicators of the injurious effects of the products. The results showed large differences in irritation potential between the products, and some of them demonstrated considerable damaging effect. Moreover, the study proved the presence of barrier-impairing residues on the skin after rinsing with water. Subclinical skin damage can make the skin vulnerable to further irritation and delay recovery of chronic irritant contact dermatitis.

Effects of soap and detergents on skin surface pH, stratum corneum hydration and fat content in infants.

PubMed

Gfatter, R; Hackl, P; Braun, F

1997-01-01

In adults the influence of cleansing preparations on the pH, fat content and hydration of the skin is well documented. Studies in newborn and small infants have not been reported. Our study aimed at examining whether similar effects can be ascertained in infants. Infants without skin disease, aged 2 weeks to 16 months, entered an open, controlled and randomized study. Ten infants each had skin washed with tap water (control group), liquid detergent (pH 5.5), compact detergent (pH 5.5) or alkaline soap (pH 9.5). The pH, fat content and hydration were measured before and 10 min after cleansing. Findings were statistically evaluated by parametric covariance analysis. The skin pH increased from an average of 6.60 after cleansing in all groups. The smallest increase (+0.19) was observed in the control group, the largest (+0.45) after washing with alkaline soap. After treatment with liquid or compact detergent, the increase of the pH was only 0.09 higher than for the control group. In comparison to the compact and liquid detergents, the alkaline soap group had a significantly higher increase in pH. The fat content (mean starting value: 4.34 micrograms/cm2) decreased after washing in all groups; the smallest effect was observed in the control group (decrease of 0.93 micrograms/cm2), the highest for the alkaline soap group (decrease of 4.81 micrograms/cm2). In comparison to the compact and liquid detergents, the alkaline soap group had a higher decrease in fat content. This difference was significant for compact detergents. No statistically significant differences were observed for hydration before versus after washing. Each cleansing agent, even normal tap water, influences the skin surface. The increase of the skin pH irritates the physiological protective 'acid mantle', changes the composition of the cutaneous bacterial flora and the activity of enzymes in the upper epidermis, which have an acid pH optimum. The dissolution of fat from the skin surface may influence the

Hand washing with soap and water together with behavioural recommendations prevents infections in common work environment: an open cluster-randomized trial

PubMed Central

2012-01-01

Background Hand hygiene is considered as an important means of infection control. We explored whether guided hand hygiene together with transmission-limiting behaviour reduces infection episodes and lost days of work in a common work environment in an open cluster-randomized 3-arm intervention trial. Methods A total of 21 clusters (683 persons) were randomized to implement hand hygiene with soap and water (257 persons), with alcohol-based hand rub (202 persons), or to serve as a control (224 persons). Participants in both intervention arms also received standardized instructions on how to limit the transmission of infections. The intervention period (16 months) included the emergence of the 2009 influenza pandemic and the subsequent national hand hygiene campaign influencing also the control arm. Results In the total follow-up period there was a 6.7% reduction of infection episodes in the soap-and water arm (p = 0.04). Before the onset of the anti-pandemic campaign, a statistically significant (p = 0.002) difference in the mean occurrence of infection episodes was observed between the control (6.0 per year) and the soap-and-water arm (5.0 per year) but not between the control and the alcohol-rub arm (5.6 per year). Neither intervention had a decreasing effect on absence from work. Conclusions We conclude that intensified hand hygiene using water and soap together with behavioural recommendations can reduce the occurrence of self-reported acute illnesses in common work environment. Surprisingly, the occurrence of reported sick leaves also increased in the soap-and water-arm. Trial Registration ClinicalTrials.gov: NCT00981877 Source of funding The Finnish Work Environment Fund and the National Institute for Health and Welfare. PMID:22243622

Scripting Module for the Satellite Orbit Analysis Program (SOAP)

NASA Technical Reports Server (NTRS)

Carnright, Robert; Paget, Jim; Coggi, John; Stodden, David

2008-01-01

This add-on module to the SOAP software can perform changes to simulation objects based on the occurrence of specific conditions. This allows the software to encompass simulation response of scheduled or physical events. Users can manipulate objects in the simulation environment under programmatic control. Inputs to the scripting module are Actions, Conditions, and the Script. Actions are arbitrary modifications to constructs such as Platform Objects (i.e. satellites), Sensor Objects (representing instruments or communication links), or Analysis Objects (user-defined logical or numeric variables). Examples of actions include changes to a satellite orbit ( v), changing a sensor-pointing direction, and the manipulation of a numerical expression. Conditions represent the circumstances under which Actions are performed and can be couched in If-Then-Else logic, like performing v at specific times or adding to the spacecraft power only when it is being illuminated by the Sun. The SOAP script represents the entire set of conditions being considered over a specific time interval. The output of the scripting module is a series of events, which are changes to objects at specific times. As the SOAP simulation clock runs forward, the scheduled events are performed. If the user sets the clock back in time, the events within that interval are automatically undone. This script offers an interface for defining scripts where the user does not have to remember the vocabulary of various keywords. Actions can be captured by employing the same user interface that is used to define the objects themselves. Conditions can be set to invoke Actions by selecting them from pull-down lists. Users define the script by selecting from the pool of defined conditions. Many space systems have to react to arbitrary events that can occur from scheduling or from the environment. For example, an instrument may cease to draw power when the area that it is tasked to observe is not in view. The contingency

The Response in Twitter to an Assisted Suicide in a Television Soap Opera.

PubMed

Scourfield, Jonathan; Colombo, Gualtiero; Evans, Rhiannon; Jacob, Nina; Le Zhang, Meng; Burnap, Pete; Edwards, Adam; Housley, William; Williams, Matthew

2016-09-01

Concern has been expressed about the potentially contagious effect of television soap opera suicides and suicidal language in social media. Twitter content was analyzed during the week in which a fictional assisted suicide was broadcast on a British television soap opera, "Coronation Street." Tweets were collected if they contained language indicating possible suicidal intent or used the word suicide. The modified Thompson tau method was used to test for any differences in the volume of tweets in both categories on the day of screening. Content analysis broke down the use of the word suicide into six thematic categories. There was no evidence on the day of screening of an increase in tweets expressing possible suicidal intent but there was an increase in tweets containing the word suicide. Content analysis found the most common thematic category to be information or support, followed by the raising of moral issues in relation to suicide. It is possible that for certain high-profile media events Twitter may be used more as a civic reactive forum than as a medium for introspection or disclosure of distress.

NCW 2002: Chemistry Keeps Us Clean. Chemists Clean Up: A History and Exploration of the Craft of Soapmaking How Soap Came to be Common in America

NASA Astrophysics Data System (ADS)

Kostka, Kim; McKay, David D.

2002-10-01

Soap is an article whose commonplace presence and obvious necessity we take for granted at the dawn of the twenty-first century. For most of American history bath soap, however, was a luxury product. This paper explores the confluence of the cultural and technological changes that led to its transformation into the ubiquitous and well-used object it is today. We pick up the timeline for the development of soap in the early American republic when soapmaking was a householder's task and soap use was generally limited to laundering clothes. We then trace the rise of the American cleanliness movement and correlate this rise to the increased manufacturing capabilities of the nation's large soapmakers. This technological forward movement included improvements in producing alkalis as well as the inception and growth of the oleochemicals industry. Additional growth agents were the development of market analysis, advertising campaigns, and factory-scale hydrolysis of fatty acids from their parent fats.

See Featured Molecules.

"In Situ" Observation of a Soap-Film Catenoid--A Simple Educational Physics Experiment

ERIC Educational Resources Information Center

Ito, Masato; Sato, Taku

2010-01-01

The solution to the Euler-Lagrange equation is an extremal functional. To understand that the functional is stationary at local extrema (maxima or minima), we propose a physics experiment that involves using a soap film to form a catenoid. A catenoid is a surface that is formed between two coaxial circular rings and is classified mathematically as…

Planetary habitability: lessons learned from terrestrial analogues

NASA Astrophysics Data System (ADS)

Preston, Louisa J.; Dartnell, Lewis R.

2014-01-01

Terrestrial analogue studies underpin almost all planetary missions and their use is essential in the exploration of our Solar system and in assessing the habitability of other worlds. Their value relies on the similarity of the analogue to its target, either in terms of their mineralogical or geochemical context, or current physical or chemical environmental conditions. Such analogue sites offer critical ground-truthing for astrobiological studies on the habitability of different environmental parameter sets, the biological mechanisms for survival in extreme environments and the preservation potential and detectability of biosignatures. The 33 analogue sites discussed in this review have been selected on the basis of their congruence to particular extraterrestrial locations. Terrestrial field sites that have been used most often in the literature, as well as some lesser known ones which require greater study, are incorporated to inform on the astrobiological potential of Venus, Mars, Europa, Enceladus and Titan. For example, the possibility of an aerial habitable zone on Venus has been hypothesized based on studies of life at high-altitudes in the terrestrial atmosphere. We also demonstrate why many different terrestrial analogue sites are required to satisfactorily assess the habitability of the changing environmental conditions throughout Martian history, and recommend particular sites for different epochs or potential niches. Finally, habitable zones within the aqueous environments of the icy moons of Europa and Enceladus and potentially in the hydrocarbon lakes of Titan are discussed and suitable analogue sites proposed. It is clear from this review that a number of terrestrial analogue sites can be applied to multiple planetary bodies, thereby increasing their value for astrobiological exploration. For each analogue site considered here, we summarize the pertinent physiochemical environmental features they offer and critically assess the fidelity with which

Sudden Thickening in Flowing Soap Films

NASA Astrophysics Data System (ADS)

Goldburg, Walter; Steers, Stanley; Hartman, Nikolaus

2007-11-01

There is no difficulty in creating soap films that flow vertically downward under gravity at speeds of the order of a m/s. If the height of the film L0 is of the order of 1 m or less, the film thickness h(x) is a few microns (The coordinate x increases downward below the injection point at x = 0.) However if L0 is of the order of 2 m, one finds that h abruptly increases at a sharply defined value of x =L. In the experiments to be described, L ˜ =.9 m. As expected, the vertical film velocity vx(x) correspondingly drops to a small fraction of its upstream value at x ˜L. In the narrow transition region from thin to thick film at x=L, both h(x) and the vx(x) oscillate at a well-defined frequency of the order of 1 Hz. The abrupt thickening is expected on the basis of singular perturbation theory (T. Tran, following paper).

Epidemiological link between wheat allergy and exposure to hydrolyzed wheat protein in facial soap.

PubMed

Fukutomi, Y; Taniguchi, M; Nakamura, H; Akiyama, K

2014-10-01

Recent studies have highlighted the importance of extra-intestinal routes of sensitization to food-related allergens as the cause of epidemics of food allergy. Instances of Japanese women developing food allergy to wheat after exposure to hydrolyzed wheat protein (HWP) present in facial soap have been reported. However, the epidemiologic impact of these ingredients as a cause of food allergy has not been well studied. To clarify the epidemiological relationship between food allergy to wheat and contact exposure to HWP, a case-control study of Japanese women aged 20-54 years with self-reported wheat allergy (WA) (cases, n = 157) and age-matched control subjects without WA (controls, n = 449) was performed using a large-scale Web-based research panel. Subjects answered a Web-based questionnaire regarding the use of skin and hair care products, as well as other possible risk factors. Current use of an HWP-containing facial soap (Cha no Shizuku; Yuka) was significantly associated with an increased risk of WA (adjusted odds ratio, 2.6; 95% confidence interval, 1.2-5.7; frequencies of current use in cases and controls; 11% and 6%, respectively). Use of Cha no Shizuku was more common in subjects with more recent-onset WA, implying that this soap may have contributed to the recent epidemic of WA. An epidemiological relationship between WA and contact exposure to HWP has been documented. This study implicates a possible role of contact exposure to food-derived protein hydrolysates as a risk factor for the development of food allergy manifesting itself as anaphylaxis. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Highly active anticancer curcumin analogues.

PubMed

Mosley, Cara A; Liotta, Dennis C; Snyder, James P

2007-01-01

Curcumin, a compound in the human food supply, represents a near-perfect starting point for drug discovery. Consequently, a number of research groups have taken the natural product as a starting point to prepare and biologically evaluate a wide variety of curcumin analogues. One widely used structural modification truncates the central conjugated beta-diketone in curcumin to the monocarbonyl dienone. A diverse array of the latter compounds exhibit cytotoxicities against an equally diverse set of cancer-related cell lines. Importantly, these compounds still retain toxicity profiles in rodents comparable to the parent natural product, whereas some analogues (e.g., EF-24, 41) exhibit good oral bioavailability and good pharmacokinetics in mice. Thiol conjugates of EF-24 analogues have been prepared that address stability and solubility issues while demonstrating cellular activities similar to the unmodified dienones. In parallel experiments, the factor VIIa-tissue factor complex (fVIIa-TF) has been exploited to develop a targeting strategy for the analogues. In particular, the EF24-FFRck-fVIIa protein conjugate is not only somewhat more effective relative to the drug alone against breast cancer and melanocyte cells. Both simple curcumin analogues and the protein conjugate evidence antiangiogenic activity in cell culture. The implication is that the fVIIa-TF targeting process, like the dienone drugs, permits a double-pronged attack with the potential to destroy a tumor directly by apoptosis.

Efficacy of Handwashing with Soap and Nail Clipping on Intestinal Parasitic Infections in School-Aged Children: A Factorial Cluster Randomized Controlled Trial.

PubMed

Mahmud, Mahmud Abdulkader; Spigt, Mark; Bezabih, Afework Mulugeta; Pavon, Ignacio Lopez; Dinant, Geert-Jan; Velasco, Roman Blanco

2015-06-01

Intestinal parasitic infections are highly endemic among school-aged children in resource-limited settings. To lower their impact, preventive measures should be implemented that are sustainable with available resources. The aim of this study was to assess the impact of handwashing with soap and nail clipping on the prevention of intestinal parasite reinfections. In this trial, 367 parasite-negative school-aged children (aged 6-15 y) were randomly assigned to receive both, one or the other, or neither of the interventions in a 2 × 2 factorial design. Assignment sequence was concealed. After 6 mo of follow-up, stool samples were examined using direct, concentration, and Kato-Katz methods. Hemoglobin levels were determined using a HemoCue spectrometer. The primary study outcomes were prevalence of intestinal parasite reinfection and infection intensity. The secondary outcome was anemia prevalence. Analysis was by intention to treat. Main effects were adjusted for sex, age, drinking water source, latrine use, pre-treatment parasites, handwashing with soap and nail clipping at baseline, and the other factor in the additive model. Fourteen percent (95% CI: 9% to 19%) of the children in the handwashing with soap intervention group were reinfected versus 29% (95% CI: 22% to 36%) in the groups with no handwashing with soap (adjusted odds ratio [AOR] 0.32, 95% CI: 0.17 to 0.62). Similarly, 17% (95% CI: 12% to 22%) of the children in the nail clipping intervention group were reinfected versus 26% (95% CI: 20% to 32%) in the groups with no nail clipping (AOR 0.51, 95% CI: 0.27 to 0.95). Likewise, following the intervention, 13% (95% CI: 8% to 18%) of the children in the handwashing group were anemic versus 23% (95% CI: 17% to 29%) in the groups with no handwashing with soap (AOR 0.39, 95% CI: 0.20 to 0.78). The prevalence of anemia did not differ significantly between children in the nail clipping group and those in the groups with no nail clipping (AOR 0.53, 95% CI: 0.27 to

Steiner trees and spanning trees in six-pin soap films

NASA Astrophysics Data System (ADS)

Dutta, Prasun; Khastgir, S. Pratik; Roy, Anushree

2010-02-01

The problem of finding minimum (local as well as absolute) path lengths joining given points (or terminals) on a plane is known as the Steiner problem. The Steiner problem arises in finding the minimum total road length joining several towns and cities. We study the Steiner tree problem using six-pin soap films. Experimentally, we observe spanning trees as well as Steiner trees partly by varying the pin diameter. We propose a possibly exact expression for the length of a spanning tree or a Steiner tree, which fails mysteriously in certain cases.

Ability of Hand Hygiene Interventions Using Alcohol-Based Hand Sanitizers and Soap To Reduce Microbial Load on Farmworker Hands Soiled during Harvest.

PubMed

de Aceituno, Anna Fabiszewski; Bartz, Faith E; Hodge, Domonique Watson; Shumaker, David J; Grubb, James E; Arbogast, James W; Dávila-Aviña, Jorgé; Venegas, Fabiola; Heredia, Norma; García, Santos; Leon, Juan S

2015-11-01

Effective hand hygiene is essential to prevent the spread of pathogens on produce farms and reduce foodborne illness. The U.S. Food and Drug Administration Food Safety Modernization Act Proposed Rule for Produce Safety recommends the use of soap and running water for hand hygiene of produce handlers. The use of alcohol-based hand sanitizer (ABHS) may be an effective alternative hygiene intervention where access to water is limited. There are no published data on the efficacy of either soap or ABHS-based interventions to reduce microbial contamination in agricultural settings. The goal of this study was to assess the ability of two soap-based (traditional or pumice) and two ABHS-based (label-use or two-step) hygiene interventions to reduce microbes (coliforms, Escherichia coli, and Enterococcus spp.) and soil (absorbance of hand rinsate at 600 nm [A600]) on farmworker hands after harvesting produce, compared with the results for a no-hand-hygiene control. With no hand hygiene, farmworker hands were soiled (median A600, 0.48) and had high concentrations of coliforms (geometric mean, 3.4 log CFU per hand) and Enterococcus spp. (geometric mean, 5.3 log CFU per hand) after 1 to 2 h of harvesting tomatoes. Differences in microbial loads in comparison to the loads in the control group varied by indicator organism and hygiene intervention (0 to 2.3 log CFU per hand). All interventions yielded lower concentrations of Enterococcus spp. and E. coli (P < 0.05), but not of coliforms, than were found in the control group. The two-step ABHS intervention led to significantly lower concentrations of coliforms and Enterococcus spp. than the pumice soap and label-use ABHS interventions (P < 0.05) and was the only intervention to yield significantly fewer samples with E. coli than were found in the control group (P < 0.05). All interventions removed soil from hands (P < 0.05), soap-based interventions more so than ABHS-based interventions (P < 0.05). ABHS-based interventions were

Quantum analogue computing.

PubMed

Kendon, Vivien M; Nemoto, Kae; Munro, William J

2010-08-13

We briefly review what a quantum computer is, what it promises to do for us and why it is so hard to build one. Among the first applications anticipated to bear fruit is the quantum simulation of quantum systems. While most quantum computation is an extension of classical digital computation, quantum simulation differs fundamentally in how the data are encoded in the quantum computer. To perform a quantum simulation, the Hilbert space of the system to be simulated is mapped directly onto the Hilbert space of the (logical) qubits in the quantum computer. This type of direct correspondence is how data are encoded in a classical analogue computer. There is no binary encoding, and increasing precision becomes exponentially costly: an extra bit of precision doubles the size of the computer. This has important consequences for both the precision and error-correction requirements of quantum simulation, and significant open questions remain about its practicality. It also means that the quantum version of analogue computers, continuous-variable quantum computers, becomes an equally efficient architecture for quantum simulation. Lessons from past use of classical analogue computers can help us to build better quantum simulators in future.

The effect of handwashing at recommended times with water alone and with soap on child diarrhea in rural Bangladesh: an observational study.

PubMed

Luby, Stephen P; Halder, Amal K; Huda, Tarique; Unicomb, Leanne; Johnston, Richard B

2011-06-01

Standard public health interventions to improve hand hygiene in communities with high levels of child mortality encourage community residents to wash their hands with soap at five separate key times, a recommendation that would require mothers living in impoverished households to typically wash hands with soap more than ten times per day. We analyzed data from households that received no intervention in a large prospective project evaluation to assess the relationship between observed handwashing behavior and subsequent diarrhea. Fieldworkers conducted a 5-hour structured observation and a cross-sectional survey in 347 households from 50 villages across rural Bangladesh in 2007. For the subsequent 2 years, a trained community resident visited each of the enrolled households every month and collected information on the occurrence of diarrhea in the preceding 48 hours among household residents under the age of 5 years. Compared with children living in households where persons prepared food without washing their hands, children living in households where the food preparer washed at least one hand with water only (odds ratio [OR]=0.78; 95% confidence interval [CI]=0.57-1.05), washed both hands with water only (OR=0.67; 95% CI=0.51-0.89), or washed at least one hand with soap (OR=0.30; 95% CI=0.19-0.47) had less diarrhea. In households where residents washed at least one hand with soap after defecation, children had less diarrhea (OR=0.45; 95% CI=0.26-0.77). There was no significant association between handwashing with or without soap before feeding a child, before eating, or after cleaning a child's anus who defecated and subsequent child diarrhea. These observations suggest that handwashing before preparing food is a particularly important opportunity to prevent childhood diarrhea, and that handwashing with water alone can significantly reduce childhood diarrhea.

The mixture of liquid foam soap, ethanol and citric acid as a new fixative-preservative solution in veterinary anatomy.

PubMed

Turan, Erkut; Gules, Ozay; Kilimci, Figen Sevil; Kara, Mehmet Erkut; Dilek, Omer Gurkan; Sabanci, Seyyid Said; Tatar, Musa

2017-01-01

The present study investigates the efficiency of liquid foam soap, ethanol, citric acid and benzalkonium chloride as a fixative-preservative solution (a soap-and ethanol-based fixing solution, or SEFS). In this study, ethanol serves as the fixative and preservative, liquid foam soap as the modifying agent, citric acid as the antioxidant and benzalkonium chloride as the disinfectant. The goat cadavers perfused with SEFS (n=8) were evaluated over a period of one year with respect to hardness, colour and odour using objective methods. Colour and hardness were compared between one fresh cadaver and the SEFS-embalmed cadavers. Histological and microbiological examinations were also performed in tissue samples. Additionally, the cadavers were subjectively evaluated after dissection and palpation. The SEFS provided the effectiveness expected over a 1-year embalming period for the animal cadavers. No bacteria or fungi were isolated except for some non-pathogenic Bacillus species. Visible mould was not present on either cadavers or in the surrounding environment. The cadavers maintained an appearance close to their original anatomical appearance, with muscles having good hardness and elasticity for dissection. Copyright © 2016 Elsevier GmbH. All rights reserved.

Washing with hope: evidence of improved handwashing among children in South Africa from a pilot study of a novel soap technology.

PubMed

Burns, Justine; Maughan-Brown, Brendan; Mouzinho, Âurea

2018-06-07

While regular handwashing effectively reduces communicable disease incidence and related child mortality, instilling a habit of regular handwashing in young children continues to be a challenging task, especially in developing country contexts. This randomised controlled pilot study assessed the effect of a novel handwashing intervention - a bi-monthly delivery of a colourful, translucent bar of soap with a toy embedded in its centre (HOPE SOAP©) - on children's handwashing behaviour and health outcomes. Between September and December 2014, 203 households in an impoverished community in Cape Town, South Africa, were randomised (1:1) to the control group or to receive HOPE SOAP©. Of all children (N = 287) aged 3-9 years and not enrolled in early childhood development programmes, 153 residing in intervention households received a bar of HOPE SOAP© every two weeks (total of 4 bars). Children in control households received a colourful, translucent bar of soap of equal size to HOPE SOAP©, with a toy alongside it. Two 'snack tests' (children were offered crackers and jam) were used to provide objective observational measures of handwashing. Through baseline and endline surveys, data were collected from caregivers on the frequency (scale of 1-10) of handwashing by children after using the toilet and before meals, and on soap-use during handwashing. Data on 14 illnesses/symptoms of illness experienced by children in the two weeks preceding the surveys were collected. Multivariable Ordinary Least Squares regression analyses were used to assess the intervention effect on handwashing behaviours and health outcomes. At endline, HOPE SOAP© children were directly observed as being more likely to wash their hands unprompted at both snack tests (49% vs 39%, β: 0.10, p = 0.27). They were more likely to score ≥8/10 for using soap when washing their hands (β: 0.14, p = 0.011). HOPE SOAP© children, in general, had better health outcomes, and those who used the

A SOAP Web Service for accessing MODIS land product subsets

DOE Office of Scientific and Technical Information (OSTI.GOV)

SanthanaVannan, Suresh K; Cook, Robert B; Pan, Jerry Yun

2011-01-01

Remote sensing data from satellites have provided valuable information on the state of the earth for several decades. Since March 2000, the Moderate Resolution Imaging Spectroradiometer (MODIS) sensor on board NASA s Terra and Aqua satellites have been providing estimates of several land parameters useful in understanding earth system processes at global, continental, and regional scales. However, the HDF-EOS file format, specialized software needed to process the HDF-EOS files, data volume, and the high spatial and temporal resolution of MODIS data make it difficult for users wanting to extract small but valuable amounts of information from the MODIS record. Tomore » overcome this usability issue, the NASA-funded Distributed Active Archive Center (DAAC) for Biogeochemical Dynamics at Oak Ridge National Laboratory (ORNL) developed a Web service that provides subsets of MODIS land products using Simple Object Access Protocol (SOAP). The ORNL DAAC MODIS subsetting Web service is a unique way of serving satellite data that exploits a fairly established and popular Internet protocol to allow users access to massive amounts of remote sensing data. The Web service provides MODIS land product subsets up to 201 x 201 km in a non-proprietary comma delimited text file format. Users can programmatically query the Web service to extract MODIS land parameters for real time data integration into models, decision support tools or connect to workflow software. Information regarding the MODIS SOAP subsetting Web service is available on the World Wide Web (WWW) at http://daac.ornl.gov/modiswebservice.« less

Efficacy of Handwashing with Soap and Nail Clipping on Intestinal Parasitic Infections in School-Aged Children: A Factorial Cluster Randomized Controlled Trial

PubMed Central

Mahmud, Mahmud Abdulkader; Spigt, Mark; Bezabih, Afework Mulugeta; Pavon, Ignacio Lopez; Dinant, Geert-Jan; Velasco, Roman Blanco

2015-01-01

Background Intestinal parasitic infections are highly endemic among school-aged children in resource-limited settings. To lower their impact, preventive measures should be implemented that are sustainable with available resources. The aim of this study was to assess the impact of handwashing with soap and nail clipping on the prevention of intestinal parasite reinfections. Methods and Findings In this trial, 367 parasite-negative school-aged children (aged 6–15 y) were randomly assigned to receive both, one or the other, or neither of the interventions in a 2 × 2 factorial design. Assignment sequence was concealed. After 6 mo of follow-up, stool samples were examined using direct, concentration, and Kato-Katz methods. Hemoglobin levels were determined using a HemoCue spectrometer. The primary study outcomes were prevalence of intestinal parasite reinfection and infection intensity. The secondary outcome was anemia prevalence. Analysis was by intention to treat. Main effects were adjusted for sex, age, drinking water source, latrine use, pre-treatment parasites, handwashing with soap and nail clipping at baseline, and the other factor in the additive model. Fourteen percent (95% CI: 9% to 19%) of the children in the handwashing with soap intervention group were reinfected versus 29% (95% CI: 22% to 36%) in the groups with no handwashing with soap (adjusted odds ratio [AOR] 0.32, 95% CI: 0.17 to 0.62). Similarly, 17% (95% CI: 12% to 22%) of the children in the nail clipping intervention group were reinfected versus 26% (95% CI: 20% to 32%) in the groups with no nail clipping (AOR 0.51, 95% CI: 0.27 to 0.95). Likewise, following the intervention, 13% (95% CI: 8% to 18%) of the children in the handwashing group were anemic versus 23% (95% CI: 17% to 29%) in the groups with no handwashing with soap (AOR 0.39, 95% CI: 0.20 to 0.78). The prevalence of anemia did not differ significantly between children in the nail clipping group and those in the groups with no nail

Hand washing with soap and WASH educational intervention reduces under-five childhood diarrhoea incidence in Jigjiga District, Eastern Ethiopia: A community-based cluster randomized controlled trial.

PubMed

Hashi, Abdiwahab; Kumie, Abera; Gasana, Janvier

2017-06-01

Despite the tremendous achievement in reducing child mortality and morbidity in the last two decades, diarrhoea is still a major cause of morbidity and mortality among children in many developing countries, including Ethiopia. Hand washing with soap promotion, water quality improvements and improvements in excreta disposal significantly reduces diarrhoeal diseases. The objective of this study was to evaluate the effect of hand washing with soap and water, sanitation and hygiene (WASH) educational Intervention on the incidence of under-five children diarrhoea. A community-based cluster randomized controlled trial was conducted in 24 clusters (sub-Kebelles) in Jigjiga district, Somali region, Eastern Ethiopia from February 1 to July 30, 2015. The trial compared incidence of diarrhoea among under-five children whose primary caretakers receive hand washing with soap and water, sanitation, hygiene educational messages with control households. Generalized estimating equation with a log link function Poisson distribution family was used to compute adjusted incidence rate ratio and the corresponding 95% confidence interval. The results of this study show that the longitudinal adjusted incidence rate ratio (IRR) of diarrhoeal diseases comparing interventional and control households was 0.65 (95% CI 0.57, 0.73) suggesting an overall diarrhoeal diseases reduction of 35%. The results are similar to other trials of WASH educational interventions and hand washing with soap. In conclusion, hand washing with soap practice during critical times and WASH educational messages reduces childhood diarrhoea in the rural pastoralist area.

RiskSOAP: Introducing and applying a methodology of risk self-awareness in road tunnel safety.

PubMed

Chatzimichailidou, Maria Mikela; Dokas, Ioannis M

2016-05-01

Complex socio-technical systems, such as road tunnels, can be designed and developed with more or less elements that can either positively or negatively affect the capability of their agents to recognise imminent threats or vulnerabilities that possibly lead to accidents. This capability is called risk Situation Awareness (SA) provision. Having as a motive the introduction of better tools for designing and developing systems that are self-aware of their vulnerabilities and react to prevent accidents and losses, this paper introduces the Risk Situation Awareness Provision (RiskSOAP) methodology to the field of road tunnel safety, as a means to measure this capability in this kind of systems. The main objective is to test the soundness and the applicability of RiskSOAP to infrastructure, which is advanced in terms of technology, human integration, and minimum number of safety requirements imposed by international bodies. RiskSOAP is applied to a specific road tunnel in Greece and the accompanying indicator is calculated twice, once for the tunnel design as defined by updated European safety standards and once for the 'as-is' tunnel composition, which complies with the necessary safety requirements, but calls for enhancing safety according to what EU and PIARC further suggest. The derived values indicate the extent to which each tunnel version is capable of comprehending its threats and vulnerabilities based on its elements. The former tunnel version seems to be more enhanced both in terms of it risk awareness capability and safety as well. Another interesting finding is that despite the advanced tunnel safety specifications, there is still room for enriching the safe design and maintenance of the road tunnel. Copyright © 2016 Elsevier Ltd. All rights reserved.

Control of E-cadherin apical localisation and morphogenesis by a SOAP-1/AP-1/clathrin pathway in C. elegans epidermal cells.

PubMed

Gillard, Ghislain; Shafaq-Zadah, Massiullah; Nicolle, Ophélie; Damaj, Raghida; Pécréaux, Jacques; Michaux, Grégoire

2015-05-01

E-cadherin (E-cad) is the main component of epithelial junctions in multicellular organisms, where it is essential for cell-cell adhesion. The localisation of E-cad is often strongly polarised in the apico-basal axis. However, the mechanisms required for its polarised distribution are still largely unknown. We performed a systematic RNAi screen in vivo to identify genes required for the strict E-cad apical localisation in C. elegans epithelial epidermal cells. We found that the loss of clathrin, its adaptor AP-1 and the AP-1 interactor SOAP-1 induced a basolateral localisation of E-cad without affecting the apico-basal diffusion barrier. We further found that SOAP-1 controls AP-1 localisation, and that AP-1 is required for clathrin recruitment. Finally, we also show that AP-1 controls E-cad apical delivery and actin organisation during embryonic elongation, the final morphogenetic step of embryogenesis. We therefore propose that a molecular pathway, containing SOAP-1, AP-1 and clathrin, controls the apical delivery of E-cad and morphogenesis. © 2015. Published by The Company of Biologists Ltd.

The Use of Empirical Methods for Testing Granular Materials in Analogue Modelling

PubMed Central

Montanari, Domenico; Agostini, Andrea; Bonini, Marco; Corti, Giacomo; Del Ventisette, Chiara

2017-01-01

The behaviour of a granular material is mainly dependent on its frictional properties, angle of internal friction, and cohesion, which, together with material density, are the key factors to be considered during the scaling procedure of analogue models. The frictional properties of a granular material are usually investigated by means of technical instruments such as a Hubbert-type apparatus and ring shear testers, which allow for investigating the response of the tested material to a wide range of applied stresses. Here we explore the possibility to determine material properties by means of different empirical methods applied to mixtures of quartz and K-feldspar sand. Empirical methods exhibit the great advantage of measuring the properties of a certain analogue material under the experimental conditions, which are strongly sensitive to the handling techniques. Finally, the results obtained from the empirical methods have been compared with ring shear tests carried out on the same materials, which show a satisfactory agreement with those determined empirically. PMID:28772993

Patients' preferences when comparing analogue implant impressions using a polyether impression material versus digital impressions (Intraoral Scan) of dental implants.

PubMed

Wismeijer, Daniel; Mans, Ronny; van Genuchten, Michiel; Reijers, Hajo A

2014-10-01

The primary objective of this clinical study was to assess the patients' perception of the difference between an analogue impression approach on the one hand and an intra-oral scan (IO scan) on the other when restoring implants in the non-aesthetic zone. A second objective was to analyse the difference in time needed to perform these two procedures. Thirty consecutive patients who had received 41 implants (Straumann tissue level) in the non-aesthetic zone in an implant-based referral practice setting in the Netherlands. As they were to receive crown and or bridge work on the implants, in one session, the final impressions were taken with both an analogue technique and with an intraoral scan. Patients were also asked if, directly after the treatment was carried out, they would be prepared to fill out a questionnaire on their perception of both techniques. The time involved following these two procedures was also recorded. The preparatory activities of the treatment, the taste of the impression material and the overall preference of the patients were significantly in favour of the IO scan. The bite registration, the scan head and gag reflex positively tended to the IO scan, but none of these effects were significant. The overall time involved with the IO scan was more negatively perceived than the analogue impression. Overall less time was involved when following the analogue impression technique than with the IO scan. The overall preference of the patients in our sample is significantly in favour of the approach using the IO scan. This preference relates mainly to the differences between the compared approaches with respect to taste effects and their preparatory activities. The patients did perceive the duration of IO scan more negatively than the analogue impression approach. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Implementation and Assessment of Undergraduate Experiences in SOAP: An Atmospheric Science Research and Education Program

ERIC Educational Resources Information Center

Hopper, Larry J., Jr.; Schumacher, Courtney; Stachnik, Justin P.

2013-01-01

The Student Operational Aggie Doppler Radar Project (SOAP) involved 95 undergraduates in a research and education program to better understand the climatology of storms in southeast Texas from 2006-2010. This paper describes the structure, components, and implementation of the 1-credit-hour research course, comparing first-year participants'…

Wake visualization of a heaving and pitching foil in a soap film

NASA Astrophysics Data System (ADS)

Muijres, Florian T.; Lentink, David

2007-11-01

Many fish depend primarily on their tail beat for propulsion. Such a tail is commonly modeled as a two-dimensional flapping foil. Here we demonstrate a novel experimental setup of such a foil that heaves and pitches in a soap film. The vortical flow field generated by the foil correlates with thickness variations in the soap film, which appear as interference fringes when the film is illuminated with a monochromatic light source (we used a high-frequency SOX lamp). These interference fringes are subsequently captured with high-speed video (500 Hz) and this allows us to study the unsteady vortical field of a flapping foil. The main advantage of our approach is that the flow fields are time and space resolved and can be obtained time-efficiently. The foil is driven by a flapping mechanism that is optimized for studying both fish swimming and insect flight inside and outside the behavioral envelope. The mechanism generates sinusoidal heave and pitch kinematics, pre-described by the non-dimensional heave amplitude (0-6), the pitch amplitude (0°-90°), the phase difference between pitch and heave (0°-360°), and the dimensionless wavelength of the foil (3-18). We obtained this wide range of wavelengths for a foil 4 mm long by minimizing the soap film speed (0.25 m s-1) and maximizing the flapping frequency range (4-25 Hz). The Reynolds number of the foil is of order 1,000 throughout this range. The resulting setup enables an effective assessment of vortex wake topology as a function of flapping kinematics. The efficiency of the method is further improved by carefully eliminating background noise in the visualization (e.g., reflections of the mechanism). This is done by placing mirrors at an angle behind the translucent film such that the camera views the much more distant and out-of-focus reflections of the black laboratory wall. The resulting high-quality flow visualizations require minimal image processing for flow interpretation. Finally, we demonstrate the

Wake visualization of a heaving and pitching foil in a soap film

NASA Astrophysics Data System (ADS)

Muijres, Florian T.; Lentink, David

Many fish depend primarily on their tail beat for propulsion. Such a tail is commonly modeled as a twodimensional flapping foil. Here we demonstrate a novel experimental setup of such a foil that heaves and pitches in a soap film. The vortical flow field generated by the foil correlates with thickness variations in the soap film, which appear as interference fringes when the film is illuminated with a monochromatic light source (we used a high-frequency SOX lamp). These interference fringes are subsequently captured with high-speed video (500 Hz) and this allows us to study the unsteady vortical field of a flapping foil. The main advantage of our approach is that the flow fields are time and space resolved and can be obtained time-efficiently. The foil is driven by a flapping mechanism that is optimized for studying both fish swimming and insect flight inside and outside the behavioral envelope. The mechanism generates sinusoidal heave and pitch kinematics, pre-described by the non-dimensional heave amplitude (0-6), the pitch amplitude (0° - 90°), the phase difference between pitch and heave (0° - 360°), and the dimensionless wavelength of the foil (3-18). We obtained this wide range of wavelengths for a foil 4 mm long by minimizing the soap film speed (0.25 m s- 1) and maximizing the flapping frequency range (4-25 Hz). The Reynolds number of the foil is of order 1,000 throughout this range. The resulting setup enables an effective assessment of vortex wake topology as a function of flapping kinematics. The efficiency of the method is further improved by carefully eliminating background noise in the visualization (e.g., reflections of the mechanism). This is done by placing mirrors at an angle behind the translucent film such that the camera views the much more distant and out-of-focus reflections of the black laboratory wall. The resulting high-quality flow visualizations require minimal image processing for flow interpretation. Finally, we demonstrate the

Intensity of vortices: from soap bubbles to hurricanes

PubMed Central

Meuel, T.; Xiong, Y. L.; Fischer, P.; Bruneau, C. H.; Bessafi, M.; Kellay, H.

2013-01-01

By using a half soap bubble heated from below, we obtain large isolated single vortices whose properties as well as their intensity are measured under different conditions. By studying the effects of rotation of the bubble on the vortex properties, we found that rotation favors vortices near the pole. Rotation also inhibits long life time vortices. The velocity and vorticity profiles of the vortices obtained are well described by a Gaussian vortex. Besides, the intensity of these vortices can be followed over long time spans revealing periods of intensification accompanied by trochoidal motion of the vortex center, features which are reminiscent of the behavior of tropical cyclones. An analysis of this intensification period suggests a simple relation valid for both the vortices observed here and for tropical cyclones. PMID:24336410

Confocal micro-Raman spectroscopy of black soap films

NASA Astrophysics Data System (ADS)

Lecourt, B.; Capelle, F.; Adamietz, F.; Malaplate, A.; Blaudez, D.; Kellay, H.; Turlet, J. M.

1998-01-01

Black soap films from aqueous solutions of sodium dodecyl sulphate are studied by micro-Raman confocal spectroscopy. At the end of the draining process films of different thicknesses are obtained depending on the experimental conditions: Working in a closed humidified chamber leads to common black films while, under evaporation or in the presence of electrolyte, Newton black films are observed. From the Raman spectra of these films, quantitative information is deduced about the conformational and lateral order of the aliphatic surfactant chains, as well as the thickness of the residual water layer. More accurate measurements of the thickness of these ultimate films have been carried out by transmission ellipsometry and their effective refractive index measured by Brewster angle reflectivity. The thinner films present higher molecular organization and their aqueous core exhibits unusual spectral features.

Larvicidal effect of disinfectant soap on Anopheles gambiae s.s (Diptera: Culicidae) in laboratory and semifield environs

PubMed Central

2014-01-01

Background Mosquito larval control using chemicals and biological agents is of paramount importance in vector population and disease incidence reduction. A commercial synthetic disinfectant soap was evaluated against larvae of Anopheles gambiae s.s. in both laboratory and semi field conditions. Method Five concentrations of commercial synthetic disinfectant soap (0.0001, 0.001, 0.01, 0.1 and 1%) were prepared and evaluated against third instar larvae in laboratory and semi field environments. Mortality was scored at 12, 24, 48, and 72 hrs. Each dosage had 6 replicates, having twenty 3rd instar larvae of An.gambiae s.s. Results In the laboratory phase, all dosages had significantly higher larval mortalities than in controls, while in semi field conditions, the dosages of 0.0001, 0.001 and 0.01% had lower mortalities than laboratory trials. In the comparison between semi field and laboratory trials, only 0.1 and 1% dosage had significant difference with more mortality in semifield conditions. Proportions of larvae that died during mortality monitoring intervals in laboratory and semi field had significant differences only at 12 hrs and 72 hrs. Conclusion The findings of this study have demonstrated that the mortality of larvae caused by commercial synthetic disinfectant soap is worth further studies in open water bodies. More studies are necessary to find out the effect of sunlight on the chemistry of the synthetic disinfectant and other variables in small scale full field trials. PMID:24885903

Larvicidal effect of disinfectant soap on Anopheles gambiae s.s (Diptera: Culicidae) in laboratory and semifield environs.

PubMed

Mdoe, France P; Nkwengulila, Gamba; Chobu, Mariam; Lyaruu, Lucile; Gyunda, Israel L; Mbepera, Saada; Xue, Rui-De; Kweka, Eliningaya J

2014-05-03

Mosquito larval control using chemicals and biological agents is of paramount importance in vector population and disease incidence reduction. A commercial synthetic disinfectant soap was evaluated against larvae of Anopheles gambiae s.s. in both laboratory and semi field conditions. Five concentrations of commercial synthetic disinfectant soap (0.0001, 0.001, 0.01, 0.1 and 1%) were prepared and evaluated against third instar larvae in laboratory and semi field environments. Mortality was scored at 12, 24, 48, and 72 hrs. Each dosage had 6 replicates, having twenty 3rd instar larvae of An.gambiae s.s. In the laboratory phase, all dosages had significantly higher larval mortalities than in controls, while in semi field conditions, the dosages of 0.0001, 0.001 and 0.01% had lower mortalities than laboratory trials. In the comparison between semi field and laboratory trials, only 0.1 and 1% dosage had significant difference with more mortality in semifield conditions. Proportions of larvae that died during mortality monitoring intervals in laboratory and semi field had significant differences only at 12 hrs and 72 hrs. The findings of this study have demonstrated that the mortality of larvae caused by commercial synthetic disinfectant soap is worth further studies in open water bodies. More studies are necessary to find out the effect of sunlight on the chemistry of the synthetic disinfectant and other variables in small scale full field trials.

Quantitative structure-activity relationship analysis of the pharmacology of para-substituted methcathinone analogues.

PubMed

Bonano, J S; Banks, M L; Kolanos, R; Sakloth, F; Barnier, M L; Glennon, R A; Cozzi, N V; Partilla, J S; Baumann, M H; Negus, S S

2015-05-01

Methcathinone (MCAT) is a potent monoamine releaser and parent compound to emerging drugs of abuse including mephedrone (4-CH3 MCAT), the para-methyl analogue of MCAT. This study examined quantitative structure-activity relationships (QSAR) for MCAT and six para-substituted MCAT analogues on (a) in vitro potency to promote monoamine release via dopamine and serotonin transporters (DAT and SERT, respectively), and (b) in vivo modulation of intracranial self-stimulation (ICSS), a behavioural procedure used to evaluate abuse potential. Neurochemical and behavioural effects were correlated with steric (Es ), electronic (σp ) and lipophilic (πp ) parameters of the para substituents. For neurochemical studies, drug effects on monoamine release through DAT and SERT were evaluated in rat brain synaptosomes. For behavioural studies, drug effects were tested in male Sprague-Dawley rats implanted with electrodes targeting the medial forebrain bundle and trained to lever-press for electrical brain stimulation. MCAT and all six para-substituted analogues increased monoamine release via DAT and SERT and dose- and time-dependently modulated ICSS. In vitro selectivity for DAT versus SERT correlated with in vivo efficacy to produce abuse-related ICSS facilitation. In addition, the Es values of the para substituents correlated with both selectivity for DAT versus SERT and magnitude of ICSS facilitation. Selectivity for DAT versus SERT in vitro is a key determinant of abuse-related ICSS facilitation by these MCAT analogues, and steric aspects of the para substituent of the MCAT scaffold (indicated by Es ) are key determinants of this selectivity. © 2014 The British Pharmacological Society.

Quantitative structure–activity relationship analysis of the pharmacology of para-substituted methcathinone analogues

PubMed Central

Bonano, J S; Banks, M L; Kolanos, R; Sakloth, F; Barnier, M L; Glennon, R A; Cozzi, N V; Partilla, J S; Baumann, M H; Negus, S S

2015-01-01

Background and Purpose Methcathinone (MCAT) is a potent monoamine releaser and parent compound to emerging drugs of abuse including mephedrone (4-CH3 MCAT), the para-methyl analogue of MCAT. This study examined quantitative structure–activity relationships (QSAR) for MCAT and six para-substituted MCAT analogues on (a) in vitro potency to promote monoamine release via dopamine and serotonin transporters (DAT and SERT, respectively), and (b) in vivo modulation of intracranial self-stimulation (ICSS), a behavioural procedure used to evaluate abuse potential. Neurochemical and behavioural effects were correlated with steric (Es), electronic (σp) and lipophilic (πp) parameters of the para substituents. Experimental Approach For neurochemical studies, drug effects on monoamine release through DAT and SERT were evaluated in rat brain synaptosomes. For behavioural studies, drug effects were tested in male Sprague-Dawley rats implanted with electrodes targeting the medial forebrain bundle and trained to lever-press for electrical brain stimulation. Key Results MCAT and all six para-substituted analogues increased monoamine release via DAT and SERT and dose- and time-dependently modulated ICSS. In vitro selectivity for DAT versus SERT correlated with in vivo efficacy to produce abuse-related ICSS facilitation. In addition, the Es values of the para substituents correlated with both selectivity for DAT versus SERT and magnitude of ICSS facilitation. Conclusions and Implications Selectivity for DAT versus SERT in vitro is a key determinant of abuse-related ICSS facilitation by these MCAT analogues, and steric aspects of the para substituent of the MCAT scaffold (indicated by Es) are key determinants of this selectivity. PMID:25438806

"Mary Hartman, Mary Hartman": An Analysis of Satire as a Violation of Soap Opera Stereotypes.

ERIC Educational Resources Information Center

Gaulard, Joan M.

The soap opera "Mary Hartman, Mary Hartman" presents an interesting new genre in television, as it defies the conventional standards and stereotypes associated with daytime drama. The central character is not a dependent victim but a survivor who indicates to her viewers the concept which advertisers and media management have of them. A…

"Mary Hartman, Mary Hartman"; A New Genre of Prosocial Programming, or Just Another Soap Opera?

ERIC Educational Resources Information Center

Surlin, Stuart H.; Maloof, Mary C.

This paper discusses the wide appeal, and the effect on the viewing audience, of traditional television soap operas. It reports on a comparison of role interactions, topics discussed by the characters, and types of topics and problems presented on the television program "Mary Hartman, Mary Hartman" with those presented on two traditional…

Self-perceived sensory responses to soap and synthetic detergent bars correlate with clinical signs of irritation.

PubMed

Simion, F A; Rhein, L D; Morrison, B M; Scala, D D; Salko, D M; Kligman, A M; Grove, G L

1995-02-01

Epidemiologic studies indicate that after using soaps and other personal care products, many consumers experience irritation. In 50% of the cases the feelings of skin dryness, itching, and stinging occur in the absence of visible signs of irritation. We sought to determine the relation between self-perceived sensory responses of panelists to cleansing products and clinical signs of irritation. A combination of exaggerated arm-washing methods was designed to induce clinical signs of irritation with psychometric techniques developed to quantify sensations. Two studies demonstrated that panelists could reproducibly differentiate between products on the basis of the sensations they felt and that there was a significant correlation (frequently r > 0.80) between these and the observable signs. In the case of skin dryness panelists differentiated products several washing cycles before observable differences were detected. Sensory evaluations of irritation yield additional information on soap and detergent irritancy beyond clinical observations and expand understanding of the irritation process.

Therapeutic uses of vitamin D analogues.

PubMed

Brown, A J

2001-11-01

The vitamin D endocrine system has been implicated in numerous biological activities throughout the body. The breadth and magnitude of vitamin D activity suggest potential therapeutic applications for the treatment of several diseases and disorders, including hyperproliferative diseases, immune dysfunction, endocrine disorders, and metabolic bone diseases. However, therapy using natural vitamin D hormone, 1,25-dihydroxyvitamin D(3) (1,25[OH](2)D(3)) has been precluded in most cases because of the potent calcemic activity shown by this hormone. Newly developed vitamin D analogues with lower calcemic activity have been shown to retain many therapeutic properties of 1,25(OH)(2)D(3). Molecular studies discussed in this article provide insights into the unique target cell specificity afforded by these analogues. In particular, the importance of the nuclear vitamin D receptor (VDR), serum vitamin D-binding protein, 24-hydroxylase, and membrane receptor is noted because analogue selectivity, specificity, and potency are afforded through their molecular interactions. The nuclear VDR has been isolated from a variety of target cells and tissues, suggesting that vitamin D compounds may have therapeutic potential throughout several body systems. Five vitamin D analogues have been approved for use in patients: calcipotriol (Dovonex; Leo Pharmaceuticals, Copenhagen, Denmark) for the treatment of psoriasis, 19-nor-1,25(OH)(2)D(2) (Zemplar; Abbott Laboratories, Abbott Park, IL) for secondary hyperparathyroidism, doxercalciferol (Hectorol; Bone Care Int, Madison, WI) for reduction of elevated parathyroid hormone levels, 22-oxacalcitriol (Maxacalcitol; Chugai Pharmaceuticals, Tokyo, Japan), and alfacalcidol. Several other analogues are currently being tested in preclinical and clinical trials for the treatment of various types of cancer and osteoporosis, as well as immunosuppression. Understanding how analogues exert their selective actions may allow for the design of more effective

Data aggregation in wireless sensor networks using the SOAP protocol

NASA Astrophysics Data System (ADS)

Al-Yasiri, A.; Sunley, A.

2007-07-01

Wireless sensor networks (WSN) offer an increasingly attractive method of data gathering in distributed system architectures and dynamic access via wireless connectivity. Wireless sensor networks have physical and resource limitations, this leads to increased complexity for application developers and often results in applications that are closely coupled with network protocols. In this paper, a data aggregation framework using SOAP (Simple Object Access Protocol) on wireless sensor networks is presented. The framework works as a middleware for aggregating data measured by a number of nodes within a network. The aim of the study is to assess the suitability of the protocol in such environments where resources are limited compared to traditional networks.

Efficacy of Instant Hand Sanitizers against Foodborne Pathogens Compared with Hand Washing with Soap and Water in Food Preparation Settings: A Systematic Review.

PubMed

Foddai, Antonio C G; Grant, Irene R; Dean, Moira

2016-06-01

Hands can be a vector for transmitting pathogenic microorganisms to foodstuffs and drinks, and to the mouths of susceptible hosts. Hand washing is the primary barrier to prevent transmission of enteric pathogens via cross-contamination from infected persons. Conventional hand washing involves the use of water, soap, and friction to remove dirt and microorganisms. The availability of hand sanitizing products for use when water and soap are unavailable has increased in recent years. The aim of this systematic review was to collate scientific information on the efficacy of hand sanitizers compared with washing hands with soap and water for the removal of foodborne pathogens from the hands of food handlers. An extensive literature search was carried out using three electronic databases: Web of Science, Scopus, and PubMed. Twenty-eight scientific publications were ultimately included in the review. Analysis of this literature revealed various limitations in the scientific information owing to the absence of a standardized protocol for evaluating the efficacy of hand products and variation in experimental conditions. However, despite conflicting results, scientific evidence seems to support the historical skepticism about the use of waterless hand sanitizers in food preparation settings. Water and soap appear to be more effective than waterless products for removal of soil and microorganisms from hands. Alcohol-based products achieve rapid and effective inactivation of various bacteria, but their efficacy is generally lower against nonenveloped viruses. The presence of food debris significantly affects the microbial inactivation rate of hand sanitizers.

Voting procedures from the perspective of theory of neural networks

NASA Astrophysics Data System (ADS)

Suleimenov, Ibragim; Panchenko, Sergey; Gabrielyan, Oleg; Pak, Ivan

2016-11-01

It is shown that voting procedure in any authority can be treated as Hopfield neural network analogue. It was revealed that weight coefficients of neural network which has discrete outputs -1 and 1 can be replaced by coefficients of a discrete set (-1, 0, 1). This gives us the opportunity to qualitatively analyze the voting procedure on the basis of limited data about mutual influence of members. It also proves that result of voting procedure is actually taken by network formed by voting members.

Role of soap and water in the treatment of wound dehiscence compared to normal saline plus povidone-iodine: A randomized clinical trial.

PubMed

Najafian, Aida; Fallahi, Soghra; Khorgoei, Tahereh; Ghahiri, Ataollah; Alavi, Azin; Rajaei, Minoo; Eftekhaari, Tasnim Eqbal

2015-01-01

The incidence of cesarean section is increased. About 3-30% of the women who undergo cesarean experience surgical site infections (SSIs). Many methods, have been used to decrease the incidence of SSIs, but despite much effort, no definite efficacious method has been suggested. In this parallel, single-blinded, randomized control trial, 56 women with post-surgical superficial wound dehiscence were divided into two groups in a 1:1 ratio. One group was irrigated with normal saline for irrigation and Firooz® baby soapand the other with normal saline for irrigation and povidone-iodine. Formation of granulation tissue was monitored in both groups. Also, the reason for surgery, length of wound dehiscence, and duration of hospitalization and wound union after were compared in both group's. The soap group patients were irrigated for 4.18 ± 1.96 days compared to 5.36 ± 2.83 days for the patients in povidone-iodine group (P = 0.414). The granulation tissue was formed after 3.88 ± 1.94 days in the soap group compared to 4.48 ± 2.92 days in the other group (P = 0.391), and the duration of hospitalization was 5.48 ± 2.04 days in the soap group compared to 6.3 ± 2.95 days in the other group (P = 0.423). So, no differences were observed between the two groups. It can be concluded since there is no difference between the results of two groups, irrigation with normal saline and soap is safe, easy and causes no harm or allergy compared with povidone iodine and normal saline.

Synthesis and biological evaluation of febrifugine analogues.

PubMed

Mai, Huong Doan Thi; Thanh, Giang Vo; Tran, Van Hieu; Vu, Van Nam; Vu, Van Loi; Le, Cong Vinh; Nguyen, Thuy Linh; Phi, Thi Dao; Truong, Bich Ngan; Chau, Van Minh; Pham, Van Cuong

2014-12-01

A series of febrifugine analogues were designed and synthesized. Antimalarial activity evaluation of the synthetic compounds indicated that these derivatives had a strong inhibition against both chloroquine-sensitive and -resistant Plasmodium falciparum parasites. Many of them were found to be more active than febrifugine hydrochloride. The tested analogues had also a significant cytotoxicity against four cancer cell lines (KB, MCF7, LU1 and HepG2). Among the synthetic analogues, two compounds 17b and 17h displayed a moderate cytotoxicity while they exhibited a remarkable antimalarial activity.

The SOAPS project - Spin-orbit alignment of planetary systems. Exoplanets' evolution histories in systems with different architectures

NASA Astrophysics Data System (ADS)

Faedi, F.; Gómez Maqueo Chew, Y.; Fossati, L.; Pollacco, D.; McQuillan, A.; Hebb, L.; Chaplin, W. J.; Aigrain, S.

2013-04-01

The wealth of information rendered by Kepler planets and planet candidates is indispensable for statistically significant studies of distinct planet populations, in both single and multiple systems. Empirical evidences suggest that Kepler's planet population shows different physical properties as compared to the bulk of known exoplanets. The SOAPS project, aims to shed light on Kepler's planets formation, their migration and architecture. By measuring v sini accurately for Kepler hosts with rotation periods measured from their high-precision light curves, we will assess the alignment of the planetary orbit with respect to the stellar spin axis. This degree of alignment traces the formation history and evolution of the planetary systems, and thus, allows to distinguish between different proposed migration theories. SOAPS will increase by a factor of 2 the number of spin-orbit alignment measurements pushing the parameters space down to the SuperEarth domain. Here we present our preliminary results.

Assessment of six dissimilarity metrics for climate analogues

NASA Astrophysics Data System (ADS)

Grenier, Patrick; Parent, Annie-Claude; Huard, David; Anctil, François; Chaumont, Diane

2013-04-01

Spatial analogue techniques consist in identifying locations whose recent-past climate is similar in some aspects to the future climate anticipated at a reference location. When identifying analogues, one key step is the quantification of the dissimilarity between two climates separated in time and space, which involves the choice of a metric. In this communication, spatial analogues and their usefulness are briefly discussed. Next, six metrics are presented (the standardized Euclidean distance, the Kolmogorov-Smirnov statistic, the nearest-neighbor distance, the Zech-Aslan energy statistic, the Friedman-Rafsky runs statistic and the Kullback-Leibler divergence), along with a set of criteria used for their assessment. The related case study involves the use of numerical simulations performed with the Canadian Regional Climate Model (CRCM-v4.2.3), from which three annual indicators (total precipitation, heating degree-days and cooling degree-days) are calculated over 30-year periods (1971-2000 and 2041-2070). Results indicate that the six metrics identify comparable analogue regions at a relatively large scale, but best analogues may differ substantially. For best analogues, it is also shown that the uncertainty stemming from the metric choice does generally not exceed that stemming from the simulation or model choice. A synthesis of the advantages and drawbacks of each metric is finally presented, in which the Zech-Aslan energy statistic stands out as the most recommended metric for analogue studies, whereas the Friedman-Rafsky runs statistic is the least recommended, based on this case study.

Synthesis of a new family of acyclic nucleoside phosphonates, analogues of TPases transition states.

PubMed

Dayde, Bénédicte; Benzaria, Samira; Pierra, Claire; Gosselin, Gilles; Surleraux, Dominique; Volle, Jean-Noël; Pirat, Jean-Luc; Virieux, David

2012-05-07

A 6-step procedure was developed for the synthesis of a new family of acyclic nucleoside phosphonates (ANPs), "PHEEPA" [(2-pyrimidinyl-2-(2-hydroxyethoxy)ethyl)phosphonic acids] in overall yields ranging from 4.5% to 32%. These compounds, which possess on one side a hydroxy function and on the other side a phosphonate group, can be considered either as potential antiviral agents or as transition state analogues of nucleoside phosphorylases such as thymidine phosphorylase.

AIDS soap opera generates massive interest. Eye witness: Cote d'Ivoire.

PubMed

Dodd, R

1995-12-01

SIDA Dans La Cite (AIDS in the City) is a popular weekly soap opera first broadcast in Cote d'Ivoire in 1991 with 11 15-minute episodes. The series is part of a campaign by Population Services International (PSI) to raise awareness about AIDS among Ivorian youth. Actors worked for a nominal fee, editing studios were provided at substantial discounts, and filming equipment was borrowed for next to nothing. Production director realized how important the soap opera had become after the fourth episode. A study of 700 households in Abidjan found that of the 75% who had access to a television, two-thirds had seen at least one episode. Cote d'Ivoire may be one of the most religiously conservative countries in Africa. 10% of the adult population, however, is infected with HIV. All sectors of society therefore understand the need to openly understand and discuss sexual issues in the context of such high HIV prevalence. Studies indicate that virtually everyone in Cote d'Ivoire has heard of AIDS and knows that it is a sexually transmitted disease, but persuading people to change their behavior is difficult. PSI sells approximately 750,000 of its subsidized Prudence condoms. Prudence has the same brand recognition in the country as Nescafe and Toyota. A recent survey of sexually active teens found that 30% of girls and 45% of boys used condoms. A weekly radio show is broadcast live from one of the poorest ghettos of Abidjan. Guests include popular singers, comedians, and television personalities. The actors are often from SIDA Dans La Cite.

21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

Code of Federal Regulations, 2010 CFR

2010-04-01

... represented only as soap. (b) Products intended for cleansing the human body and which are not “soap” as set... for use in cleansing the body. 701.20 Section 701.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC LABELING Labeling of Specific...

21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

Code of Federal Regulations, 2011 CFR

2011-04-01

... represented only as soap. (b) Products intended for cleansing the human body and which are not “soap” as set... use in cleansing the body. 701.20 Section 701.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC LABELING Labeling of Specific...

SOAP based web services and their future role in VO projects

NASA Astrophysics Data System (ADS)

Topf, F.; Jacquey, C.; Génot, V.; Cecconi, B.; André, N.; Zhang, T. L.; Kallio, E.; Lammer, H.; Facsko, G.; Stöckler, R.; Khodachenko, M.

2011-10-01

Modern state-of-the-art web services are from crucial importance for the interoperability of different VO tools existing in the planetary community. SOAP based web services assure the interconnectability between different data sources and tools by providing a common protocol for communication. This paper will point out a best practice approach with the Automated Multi-Dataset Analysis Tool (AMDA) developed by CDPP, Toulouse and the provision of VEX/MAG data from a remote database located at IWF, Graz. Furthermore a new FP7 project IMPEx will be introduced with a potential usage example of AMDA web services in conjunction with simulation models.

Template properties of mutagenic cytosine analogues in reverse transcription

PubMed Central

Suzuki, Tetsuya; Moriyama, Kei; Otsuka, Chie; Loakes, David; Negishi, Kazuo

2006-01-01

We have studied the mutagenic properties of ribonucleotide analogues by reverse transcription to understand their potential as antiretroviral agents by mutagenesis of the viral genome. The templating properties of nucleotide analogues including 6-(β-D-ribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c](1,2)oxazin-7-one, N4-hydroxycytidine, N4-methoxycytidine, N4-methylcytidine and 4-semicarbazidocytidine, which have been reported to exhibit ambiguous base pairing properties, were examined. We have synthesized RNA templates using T3 RNA polymerase, and investigated the specificity of the incorporation of deoxyribonucleoside triphosphates opposite these cytidine analogues in RNA by HIV and AMV reverse transcriptases. Except for N4-methylcytidine, both enzymes incorporated both dAMP and dGMP opposite these analogues in RNA. This indicates that they would be highly mutagenic if present in viral RNA. To study the basis of the differences among the analogues in the incorporation ratios of dAMP to dGMP, we have carried out kinetic analysis of incorporation opposite the analogues at a defined position in RNA templates. In addition, we examined whether the triphosphates of these analogues were incorporated competitively into RNA by human RNA polymerase II. Our present data supports the view that these cytidine analogues are mutagenic when incorporated into RNA, and that they may therefore be considered as candidates for antiviral agents by causing mutations to the retroviral genome. PMID:17130163

A systematic investigation and insight into the formation mechanism of bilayers of fatty acid/soap mixtures in aqueous solutions.

PubMed

Xu, Wenlong; Song, Aixin; Dong, Shuli; Chen, Jingfei; Hao, Jingcheng

2013-10-08

Vesicles are the most common form of bilayer structures in fatty acid/soap mixtures in aqueous solutions; however, a peculiar bilayer structure called a "planar sheet" was found for the first time in the mixtures. In the past few decades, considerable research has focused on the formation theory of bilayers in fatty acid/soap mixtures. The hydrogen bond theory has been widely accepted by scientists to explain the formation of bilayers. However, except for the hydrogen bond, no other driving forces were proposed systematically. In this work, three kinds of weak interactions were investigated in detail, which could perfectly demonstrate the formation mechanism of bilayer structures in the fatty acid/soap mixtures in aqueous solutions. (i) The influence of hydrophobic interaction was detected by changing the chain length of fatty acid (C(n)H(2n+1)COOH), in which n = 10 to 18, the phase behavior was investigated, and the phase region was presented. With the help of cryogenic transmission electron microscopy (cryo-TEM) observations, deuterium nuclear magnetic resonance ((2)H NMR), and X-ray diffraction (XRD) measurements, the vesicles and planar sheets were determined. The chain length of C(n)H(2n+1)COOH has an important effect on the physical state of the hydrophobic chain, resulting in an obvious difference in the viscoelasticity of the solution samples. (ii) The existence of hydrogen bonds between fatty acids and their soaps in aqueous solutions was demonstrated by Fourier transform infrared (FT-IR) spectroscopy and molecule dynamical simulation. From the pH measurements, the pH ranges of the bilayer formation were at the pKa values of fatty acids, respectively. (iii) Counterions can be embedded in the stern layer of the bilayers and screen the electrostatic repulsion between the COO(-) anionic headgroups. FT-IR characterization demonstrated a bidentate bridging coordination mode between counterions and carboxylates. The conductivity measurements provided the degree

Dronedarone: an amiodarone analogue.

PubMed

Doggrell, Sheila A; Hancox, Jules C

2004-04-01

Of the antiarrhythmic drugs in current use, amiodarone is one of the most effective and is associated with a comparatively low risk of drug-induced pro-arrhythmia, probably due to its multiple pharmacological actions on cardiac ion channels and receptors. However, amiodarone is associated with significant extra-cardiac side effects and this has driven development of amiodarone analogues. These analogues include short acting analogues (e.g., AT-2001) with similar acute effects to amiodarone, the thyroid receptor antagonist KB-130015 and dronedarone. Dronedarone, (SR-33589; Sanofi-Synthelabo), is a non-iodinated amiodarone derivative that inhibits Na +, K + and Ca 2+ currents. It is a potent inhibitor of the acetylcholine-activated K + current from atrial and sinoatrial nodal tissue, and inhibits the rapid delayed rectifier more potently than slow and inward rectifier K + currents and inhibits L-type calcium current. Dronedarone is an antagonist at alpha- and beta-adrenoceptors and unlike amiodarone, has little effect at thyroid receptors. Dronedarone is more potent than amiodarone in inhibiting arrhythmias and death in animal models of ischaemia- and reperfusion-induced arrhythmias. In the Dronedarone Atrial Fibrillation Study After Electrical Cardioversion (DAFNE) clinical trial, dronedarone 800 mg/day appeared to be effective and safe for the prevention of atrial fibrillation relapses after cardioversion. The Antiarrhythmic Trial with Dronedarone in Moderate-to-Severe Congestive Heart Failure Evaluating Morbidity Decrease (ANDROMEDA) trial was stopped due to a potential increased risk of death in the dronedarone group. Trials of dronedarone in the maintenance of sinus rhythm in patients with atrial fibrillation and a safety and tolerability study in patients with an implantable cardioverter defibrillator are ongoing. Further experimental and clinical studies are required before we have a definitive answer to whether dronedarone has advantages over amiodarone and

A novel lunar bed rest analogue.

PubMed

Cavanagh, Peter R; Rice, Andrea J; Licata, Angelo A; Kuklis, Matthew M; Novotny, Sara C; Genc, Kerim O; Englehaupt, Ricki K; Hanson, Andrea M

2013-11-01

Humans will eventually return to the Moon and thus there is a need for a ground-based analogue to enable the study of physiological adaptations to lunar gravity. An important unanswered question is whether or not living on the lunar surface will provide adequate loading of the musculoskeletal system to prevent or attenuate the bone loss that is seen in microgravity. Previous simulations have involved tilting subjects to an approximately 9.5 degrees angle to achieve a lunar gravity component parallel to the long-axis of the body. However, subjects in these earlier simulations were not weight-bearing, and thus these protocols did not provide an analogue for load on the musculoskeletal system. We present a novel analogue which includes the capability to simulate standing and sitting in a lunar loading environment. A bed oriented at a 9.5 degrees angle was mounted on six linear bearings and was free to travel with one degree of freedom along rails. This allowed approximately 1/6 body weight loading of the feet during standing. "Lunar" sitting was also successfully simulated. A feasibility study demonstrated that the analogue was tolerated by subjects for 6 d of continuous bed rest and that the reaction forces at the feet during periods of standing were a reasonable simulation of lunar standing. During the 6 d, mean change in the volume of the quadriceps muscles was -1.6% +/- 1.7%. The proposed analogue would appear to be an acceptable simulation of lunar gravity and deserves further exploration in studies of longer duration.

Martian Feeling: An Analogue Study to Simulate a Round-Trip to Mars using the International Space Station

NASA Astrophysics Data System (ADS)

Felix, C. V.; Gini, A.

When talking about human space exploration, Mars missions are always present. It is clear that sooner or later, humanity will take this adventure. Arguably the most important aspect to consider for the success of such an endeavour is the human element. The safety of the crew throughout a Martian mission is a top priority for all space agencies. Therefore, such a mission should not take place until all the risks have been fully understood and mitigated. A mission to Mars presents unique human and technological challenges in terms of isolation, confinement, autonomy, reliance on mission control, communication delays and adaptation to different gravity levels. Analogue environments provide the safest way to simulate these conditions, mitigate the risks and evaluate the effects of long-term space travel on the crew. Martian Feeling is one of nine analogue studies, from the Mars Analogue Path (MAP) report [1], proposed by the TP Analogue group of ISU Masters class 2010. It is an integrated analogue study which simulates the psychological, physiological and operational conditions that an international, six-person, mixed gender crew would experience on a mission to Mars. Set both onboard the International Space Station (ISS) and on Earth, the Martian Feeling study will perform a ``dress rehearsal'' of a mission to Mars. The study proposes to test both human performance and operational procedures in a cost-effective manner. Since Low Earth Orbit (LEO) is more accessible than other space-based locations, an analogue studies in LEO would provide the required level of realism to a simulated transit mission to Mars. The sustained presence of microgravity and other elements of true spaceflight are features of LEO that are neither currently feasible nor possible to study in terrestrial analogue sites. International collaboration, economics, legal and ethical issues were considered when the study was proposed. As an example of international collaboration, the ISS would

The use of a measure of acute irritation to predict the outcome of repeated usage of hand soap products.

PubMed

Williams, C; Wilkinson, M; McShane, P; Pennington, D; Fernandez, C; Pierce, S

2011-06-01

Healthcare-associated infection is an important worldwide problem that could be reduced by better hand hygiene practice. However, an increasing number of healthcare workers are experiencing irritant contact dermatitis of the hands as a result of repeated hand washing. This may lead to a reduced level of compliance with regard to hand hygiene. To assess whether a measure of acute irritation by hand soaps could predict the effects of repeated usage over a 2-week period. In a double-blind, randomized comparison study, the comparative irritation potential of four different hand soaps was assessed over a 24-h treatment period. The effect of repeated hand washing with the hand soap products over a 2-week period in healthy adult volunteers on skin barrier function was then determined by assessment of transepidermal water loss (TEWL), epidermal hydration and a visual assessment using the Hand Eczema Severity Index (HECSI) at days 0, 7 and 14. A total of 121 subjects from the 123 recruited completed phase 1 of the study. All four products were seen to be significantly different from each other in terms of the irritant reaction observed and all products resulted in a significantly higher irritation compared with the no-treatment control. Seventy-nine of the initial 121 subjects were then enrolled into the repeated usage study. A statistically significant worsening of the clinical condition of the skin as measured by HECSI was seen from baseline to day 14 in those subjects repeatedly washing their hands with two of the four soap products (products C and D) with P-values of 0·02 and 0·01, respectively. Subclinical assessment of the skin barrier function by measuring epidermal hydration was significantly increased from baseline to day 7 after repeated hand washing with products A, B and D but overall no significant change was seen in all four products tested by day 14. A statistically significant increase in TEWL at day 14 was seen for product A (P = 0·02) indicating a

Synthesis, structure, and glutathione peroxidase-like activity of amino acid containing ebselen analogues and diaryl diselenides.

PubMed

Selvakumar, Karuthapandi; Shah, Poonam; Singh, Harkesh B; Butcher, Ray J

2011-11-04

The synthesis of some ebselen analogues and diaryl diselenides, which have amino acid functions as an intramolecularly coordinating group (Se···O) has been achieved by the DCC coupling procedure. The reaction of 2,2'-diselanediylbis(5-tert-butylisophthalic acid) or the activated ester tetrakis(2,5-dioxopyrrolidin-1-yl) 2,2'-diselanediylbis(5-tert-butylisophthalate) with different C-protected amino acids (Gly, L-Phe, L-Ala, and L-Trp) afforded the corresponding ebselen analogues. The used precursor diselenides have been found to undergo facile intramolecular cyclization during the amide bond formation reaction. In contrast, the DCC coupling of 2,2'-diselanediyldibenzoic acid with C-protected amino acids (Gly, L/D-Ala and L-Phe) affords the corresponding amide derivatives and not the ebselen analogues. Some of the representative compounds have been structurally characterized by single-crystal X-ray crystallography. The glutathione peroxidase (GPx)-like activities of the ebselen analogues and the diaryl diselenides have been evaluated by using the coupled reductase assay method. Intramolecularly stabilized ebselen analogues show slightly higher maximal velocity (V(max)) than ebselen. However, they do not show any GPx-like activity at low GSH concentrations at which ebselen and related diselenides are active. This could be attributed to the peroxide-mediated intramolecular cyclization of the corresponding selenenyl sulfide and diaryl diselenide intermediates generated during the catalytic cycle. Interestingly, the diaryl diselenides with alanine (L,L or D,D) amide moieties showed excellent catalytic efficiency (k(cat)/K(M)) with low K(M) values in comparison to the other compounds. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Uncovering mass segregation with galaxy analogues in dark-matter simulations

NASA Astrophysics Data System (ADS)

Joshi, Gandhali D.; Parker, Laura C.; Wadsley, James

2016-10-01

We investigate mass segregation in group and cluster environments by identifying galaxy analogues in high-resolution dark-matter simulations. Subhaloes identified by the Amiga's Halo Finder (AHF) and ROCKSTAR halo finders have similar mass functions, independent of resolution, but different radial distributions due to significantly different subhalo hierarchies. We propose a simple way to classify subhaloes as galaxy analogues. The radial distributions of galaxy analogues agree well at large halocentric radii for both AHF and ROCKSTAR but disagree near parent halo centres where the phase-space information used by ROCKSTAR is essential. We see clear mass segregation at small radii (within 0.5 rvir) with average galaxy analogue mass decreasing with radius. Beyond the virial radius, we find a mild trend where the average galaxy analogue mass increases with radius. These mass segregation trends are strongest in small groups and dominated by the segregation of low-mass analogues. The lack of mass segregation in massive galaxy analogues suggests that the observed trends are driven by the complex accretion histories of the parent haloes rather than dynamical friction.

SOAP. A tool for the fast computation of photometry and radial velocity induced by stellar spots

NASA Astrophysics Data System (ADS)

Boisse, I.; Bonfils, X.; Santos, N. C.

2012-09-01

We define and put at the disposal of the community SOAP, Spot Oscillation And Planet, a software tool that simulates the effect of stellar spots and plages on radial velocimetry and photometry. This paper describes the tool release and provides instructions for its use. We present detailed tests with previous computations and real data to assess the code's performance and to validate its suitability. We characterize the variations of the radial velocity, line bisector, and photometric amplitude as a function of the main variables: projected stellar rotational velocity, filling factor of the spot, resolution of the spectrograph, linear limb-darkening coefficient, latitude of the spot, and inclination of the star. Finally, we model the spot distributions on the active stars HD 166435, TW Hya and HD 189733, which reproduce the observations. We show that the software is remarkably fast, allowing several evolutions in its capabilities that could be performed to study the next challenges in the exoplanetary field connected with the stellar variability. The tool is available at http://www.astro.up.pt/soap

Spectroscopic Determination of Triclosan Concentration in a Series of Antibacterial Soaps: A First-Year Undergraduate Laboratory Experiment

ERIC Educational Resources Information Center

Wyllie, Graeme R. A.

2015-01-01

The antibacterial chemical triclosan is a common component in personal care products but recently the subject of many reports concerning environmental toxicity and health impacts. Although triclosan concentration in a soap can be determined simply via high-performance liquid chromatography, this is a technique not routinely available in the…

A Procedure for the Design of Air-Heated Ice-Prevention Systems

NASA Technical Reports Server (NTRS)

Neel, C. B.

1954-01-01

A procedure proposed for use in the design of air-heated systems for the continuous prevention of ice formation on airplane components is set forth. Required heat-transfer and air-pressure-loss equations are presented, and methods of selecting appropriate meteorological conditions for flight over specified geographical areas and for the calculation of water-drop-impingement characteristics are suggested. In order to facilitate the design, a simple electrical analogue was devised which solves the complex heat-transfer relationships existing in the thermal-system analysis. The analogue is described and an illustration of its application to design is given.

Conformationally restrained aromatic analogues of fosmidomycin and FR900098.

PubMed

Kurz, Thomas; Schlüter, Katrin; Pein, Miriam; Behrendt, Christoph; Bergmann, Bärbel; Walter, Rolf D

2007-07-01

The synthesis and in-vitro antimalarial activity of conformationally restrained bis(pivaloyloxymethyl) ester analogues of the natural product fosmidomycin is presented. In contrast to alpha-aryl-substituted analogues, conformationally restrained aromatic analogues exhibit only moderate in-vitro antimalarial activity against the chloroquine-sensitive strain 3D7 of Plasmodium falciparum. The most active derivative displays an IC(50) value of 47 microM.

Comparison of the immediate, residual, and cumulative antibacterial effects of Novaderm R,* Novascrub R,* Betadine Surgical Scrub, Hibiclens, and liquid soap.

PubMed

Faoagali, J; Fong, J; George, N; Mahoney, P; O'Rourke, V

1995-12-01

Triclosan (Irgasan), an antibacterial active against staphylococci and coliform bacteria, has been formulated for use as a handwash. There has been only one previous report of the use of the glove juice test to determine the immediate, residual, and cumulative effects of a 1% triclosan-based handwash product. There have been no previous studies on the use of 1% triclosan combined with povidone-iodine (PI) in a handwash product. The glove juice technique was used to document and compare the immediate, 3-hour residual, and 5-day cumulative effects on the mean log10 bacterial counts of 1% triclosan-based handwash product and 1% triclosan with 5% PI. A standardized surgical handwashing technique was used before sample collection. These results and the identity and type of the aerobic bacteria cultured from the samples were compared with the results of standardized washing and glove juice sampling with 4% weight/volume chlorhexidine gluconate (CHG), 7.5% PI, and a nonantimicrobial liquid soap. All five tested products showed significant log10 reduction from baseline on day 1, hour 0 (p < 0.05). There was no significant difference between the mean log10 bacterial count when 7.5% PI, 4% CHG, and 1% triclosan with 5% PI were compared with each other immediately after washing (p > 0.05). There was a significant difference between 1% triclosan and the liquid soap when they were each compared with 4% CHG, 7.5% PI, and 1% triclosan with 5% PI. There was no statistically significant difference between the 1% triclosan product and the liquid soap (p > 0.20). All products were effective at reducing the immediate bacterial count from the baseline level. All formulations except the liquid soap showed significant cumulative effect (p < 0.05) after multiple washes, with no significant difference between the cumulative effects of the liquid soap and 1% triclosan (p > 0.05). Both products differed significantly (p < 0.05) from the CHG, PI, and triclosan with PI. CHG, PI, and triclosan

Policy issues in space analogues

NASA Astrophysics Data System (ADS)

Auger, Robin N.; Facktor, Debra D.

Space mission planning is increasingly focusing on destinations beyond Earth orbit. Advancements in technology will inevitably be required to enable long-duration human spaceflight missions, and breakthroughs in the policy arena will also be needed to achieve success in such missions. By exploring how policy issues have been addressed in analogous extreme environments, policymakers can develop a framework for addressing these issues as they apply to long-term human spaceflight. Policy issues that need to be addressed include: crew selection, training, organization, and activities, medical testing, illness, injury, and death; communication; legal accountability and liability; mission safety and risk management; and environmental contamination. This paper outlines the approach of a study underway by The George Washington University and ANSER to examine how these policy issues have been addressed in several analogues and how the experiences of these analogues can help formulate policies for long-duration human spaceflight missions. Analogues being studied include Antarctic bases, submarine voyages, undersea stations, Biosphere 2, and the U.S. Skylab and Russian Mir space stations.

Desferrithiocin Analogue Uranium Decorporation Agents

PubMed Central

Bergeron, Raymond J.; Wiegand, Jan; Singh, Shailendra

2010-01-01

Purpose Previous systematic structure-activity studies of the desferrithiocin (DFT) platform have allowed the design and synthesis of analogues and derivatives of DFT that retain the exceptional iron-clearing activity of the parent, while eliminating its adverse effects. We hypothesized that a similar approach could be adopted to identify DFT-related analogues that could effectively decorporate uranium. Materials and Methods The decorporation properties of nine DFT-related analogues were determined in a bile duct-cannulated rat model. Diethylenetriaminepentaacetic acid (DTPA) served as a positive control. Selected ligands also underwent multiple and delayed dosing regimens. Uranium excretion in urine and bile or stool was determined by inductively coupled plasma mass spectroscopy (ICP-MS); tissue levels of uranium were also assessed. Results The two best clinical candidates are (S)-4,5-dihydro-2-[2-hydroxy-4-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylic acid [(S)-4'-(HO)-DADFT-PE (9)], with a 57% reduction in kidney uranium levels on oral (p.o.) administration and (S)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylic acid [(S)-3'-(HO)-DADFT-PE (10)], with a 62% renal reduction on p.o. administration. The majority of the metal excretion promoted by these analogues is in the bile, thus further reducing kidney actinide exposure. Conclusions While 9 administered p.o. or subcutaneously (s.c.) immediately post-metal is an effective decorporation agent, withholding the dose (s.c.) until 4 h reduced the activity of the compound. Conversion of 9 to its isopropyl ester may circumvent this issue. PMID:19399680

Soft soap as a tissue simulant medium for wound ballistic studies investigated by comparative firings with assault rifles Ak 4 and M16A1 into live, anesthetized animals.

PubMed

Janzon, B

1982-01-01

For the purpose of comparing the properties of a particular soft soap with those of live muscle tissue, a comparative study was carried out, involving firings into live, anesthetized pigs and into blocks of soft soap. The weapon - ammunition combinations utilized were Ak 4 - sk ptr 10 prj - the Swedish version of 7.62 mm NATO assault rifle M16A1- M. 193 - the U.S. standard weapon, calibre 5.56 mm. The registrations were done by flash X-ray units of 105 and 150 kilovolts, mounted in an orthogonal stereo set-up with 8-11 units, making it possible to obtain 4 to 6 measurements of bullet position, yaw angle etc. during the penetration of the target in one shot. By evaluation of these firings, and by "pooling" of the data for each series it was possible to calculate retardation force on the bullet as a function of penetration depth for the soap targets, and for the live targets. The results show that no significant difference can be discerned between the soft soap and animal tissue as regards their influence on the behaviour of the bullet.

U.S. Nuclear Regulatory Commission natural analogue research program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kovach, L.A.; Ott, W.R.

1995-09-01

This article describes the natural analogue research program of the U.S. Nuclear Regulatory Commission (US NRC). It contains information on the regulatory context and organizational structure of the high-level radioactive waste research program plan. It also includes information on the conditions and processes constraining selection of natural analogues, describes initiatives of the US NRC, and describes the role of analogues in the licensing process.

Fungal growth inhibitory properties of new phytosphingolipid analogues.

PubMed

Mormeneo, D; Manresa, A; Casas, J; Llebaria, A; Delgado, A

2008-04-01

To study the growth inhibitory properties of a series of phytosphingosine (PHS) and phytoceramide (PHC) analogues. A panel of two yeast (Candida albicans and Saccharomyces cerevisiae) and six moulds (Aspergillus repens, Aspergillus niger, Penicillium chrysogenum, Cladosporium cladosporioides, Arthroderma uncinatum and Penicillium funiculosum) has been used in this study. A series of new PHS and PHC analogues differing at the sphingoid backbone and the functional group at C1 position were synthesized. Among PHS analogues, 1-azido derivative 1c, bearing the natural D-ribo stereochemistry, showed a promising growth inhibitory profile. Among PHC analogues, compound 12, with a bulky N-pivaloyl group and a Z double bond at C3 position of the sphingoid chain, was the most active growth inhibitor. Minimal inhibitory concentration values were in the range of 23-48 micromol l(-1) for 1c and 44-87 micromol l(-1) for 12. Only scattered data on the antifungal activity of phytosphingolipids have been reported in the literature. This is the first time that a series of analogues of this kind are tested and compared to discern their structural requirements for antifungal activity.

Spurious hypocalcemia in hemodialysis patients after heparinization. In-vitro formation of calcium soaps.

PubMed

Godolphin, W; Cameron, E C; Frohlich, J; Price, J D

1979-02-01

Patients on long-term hemodialysis via arteriovenous fistula received heparin when the fistula needle was inserted, before a sample of blood was obtained for chemical analysis. The resultant release of lipoprotein lipase activity in vivo and continued lipolytic activity in vitro sometimes produced sufficient free fatty acid to precipitate calcium soaps. The consequent spurious hypocalcemia was most frequently observed when the patients had chylomicronemia. This cause of apparent hypocalcemia was eliminated either by immediate analyses of the blood samples or by obtaining samples before systemic heparinization.

Insulin analogues with improved absorption characteristics.

PubMed

Brange, J; Hansen, J F; Langkjaer, L; Markussen, J; Ribel, U; Sørensen, A R

1992-01-01

The insulin preparations available today are not ideal for therapy as s.c. injection does not provide a physiological insulin profile. With the aim to improve the absorption properties recombinant DNA technology has been utilized to design novel insulin molecules with changed physico-chemical characteristics and hence altered subcutaneous absorption kinetics. Soluble, long-acting human insulin analogues in which the isoelectric point has been increased from 5.4 to approx. 7 are absorbed very slowly, providing a more constant basal insulin delivery with lower day-to-day variation than present protracted preparations. In addition they have better storage stability. Rapid-acting human insulin analogues with largely reduced self-association are absorbed substantially faster from subcutaneous tissue than current regular insulin and thus are better suited for bolus injection. The absorption kinetics of these analogues have been able to explain the mechanism behind the dose effect on insulin absorption rate.

Synthesis and evaluation of heterocyclic analogues of bromoxynil.

PubMed

Cutulle, Matthew A; Armel, Gregory R; Brosnan, James T; Best, Michael D; Kopsell, Dean A; Bruce, Barry D; Bostic, Heidi E; Layton, Donovan S

2014-01-15

One attractive strategy to discover more active and/or crop-selective herbicides is to make structural changes to currently registered compounds. This strategy is especially appealing for those compounds with limited herbicide resistance and whose chemistry is accompanied with transgenic tools to enable herbicide tolerance in crop plants. Bromoxynil is a photosystem II (PSII) inhibitor registered for control of broadleaf weeds in several agronomic and specialty crops. Recently at the University of Tennessee-Knoxville several analogues of bromoxynil were synthesized including a previously synthesized pyridine (2,6-dibromo-5-hydroxypyridine-2-carbonitrile sodium salt), a novel pyrimidine (4,6-dibromo-5-hydroxypyrimidine-2-carbonitrile sodium salt), and a novel pyridine N-oxide (2,6-dibromo-1-oxidopyridin-1-ium-4-carbonitrile). These new analogues of bromoxynil were also evaluated for their herbicidal activity on soybean (Glycine max), cotton (Gossypium hirsutum), redroot pigweed (Amaranthus retroflexus), velvetleaf (Abutilon theophrasti), large crabgrass (Digitaria sanguinalis), and pitted morningglory ( Ipomoea lacunose ) when applied at 0.28 kg ha(-1). A second study was conducted on a glyphosate-resistant weed (Amaranthus palmeri) with the compounds being applied at 0.56 kg ha(-1). Although all compounds were believed to inhibit PSII by binding in the quinone binding pocket of D1, the pyridine and pyridine-N-oxide analogues were clearly more potent than bromoxynil on Amaranthus retroflexus. However, application of the pyrimidine herbicide resulted in the least injury to all species tested. These variations in efficacy were investigated using molecular docking simulations, which indicate that the pyridine analogue may form a stronger hydrogen bond in the pocket of the D1 protein than the original bromoxynil. A pyridine analogue was able to control the glyphosate-resistant Amaranthus palmeri with >80% efficacy. The pyridine analogues of bromoxynil showed potential

Cladribine Analogues via O⁶-(Benzotriazolyl) Derivatives of Guanine Nucleosides.

PubMed

Satishkumar, Sakilam; Vuram, Prasanna K; Relangi, Siva Subrahmanyam; Gurram, Venkateshwarlu; Zhou, Hong; Kreitman, Robert J; Montemayor, Michelle M Martínez; Yang, Lijia; Kaliyaperumal, Muralidharan; Sharma, Somesh; Pottabathini, Narender; Lakshman, Mahesh K

2015-10-09

Cladribine, 2-chloro-2'-deoxyadenosine, is a highly efficacious, clinically used nucleoside for the treatment of hairy cell leukemia. It is also being evaluated against other lymphoid malignancies and has been a molecule of interest for well over half a century. In continuation of our interest in the amide bond-activation in purine nucleosides via the use of (benzotriazol-1yl-oxy)tris(dimethylamino)phosphonium hexafluorophosphate, we have evaluated the use of O⁶-(benzotriazol-1-yl)-2'-deoxyguanosine as a potential precursor to cladribine and its analogues. These compounds, after appropriate deprotection, were assessed for their biological activities, and the data are presented herein. Against hairy cell leukemia (HCL), T-cell lymphoma (TCL) and chronic lymphocytic leukemia (CLL), cladribine was the most active against all. The bromo analogue of cladribine showed comparable activity to the ribose analogue of cladribine against HCL, but was more active against TCL and CLL. The bromo ribose analogue of cladribine showed activity, but was the least active among the C6-NH₂-containing compounds. Substitution with alkyl groups at the exocyclic amino group appears detrimental to activity, and only the C6 piperidinyl cladribine analogue demonstrated any activity. Against adenocarcinoma MDA-MB-231 cells, cladribine and its ribose analogue were most active.

Analogues of uracil nucleosides with intrinsic fluorescence (NIF-analogues): synthesis and photophysical properties.

PubMed

Segal, Meirav; Fischer, Bilha

2012-02-28

Uridine cannot be utilized as fluorescent probe due to its extremely low quantum yield. For improving the uracil fluorescence characteristics we extended the natural chromophore at the C5 position by coupling substituted aromatic rings directly or via an alkenyl or alkynyl linker to create fluorophores. Extension of the uracil base was achieved by treating 5-I-uridine with the appropriate boronic acid under the Suzuki coupling conditions. Analogues containing an alkynyl linker were obtained from 5-I-uridine and the suitable boronic acid in a Sonogashira coupling reaction. The uracil fluorescent analogues proposed here were designed to satisfy the following requirements: a minimal chemical modification at a position not involved in base-pairing, resulting in relatively long absorption and emission wavelengths and high quantum yield. 5-((4-Methoxy-phenyl)-trans-vinyl)-2'-deoxy-uridine, 6b, was found to be a promising fluorescent probe. Probe 6b exhibits a quantum yield that is 3000-fold larger than that of the natural chromophore (Φ 0.12), maximum emission (478 nm) which is 170 nm red shifted as compared to uridine, and a Stokes shift of 143 nm. In addition, since probe 6b adopts the anti conformation and S sugar puckering favored by B-DNA, it makes a promising nucleoside analogue to be incorporated in an oligonucleotide probe for detection of genetic material.

Insulin analogues for type 1 diabetes in children and adolescents.

PubMed

Galli-Tsinopoulou, A; Stergidou, D

2012-12-01

Since insulin is the unique and life-long therapy in type 1 diabetes and classical insulin preparations have certain limitations due to their pharmacokinetic and pharmacodynamic properties, the new insulin analogues aim to eliminate these limitations. Five insulin analogues are commercially available and approved for individuals with type 1 diabetes: three rapid-acting (insulin lispro, insulin aspart and insulin glulisine) and two long-acting insulin analogues (insulin glargine and insulin detemir). According to several studies conducted in children with type 1 diabetes, insulin analogues, due to their structural alterations, offer flexibility, reduction of nocturnal hypoglycemic episodes and decrease in postprandial hyperglycemic events, resulting in improved quality of life for diabetic children and their families. However, diabetes control measured with glycosylated hemoglobin A1c has been reported to be similar to conventional insulin preparations. Evidence-based medical reports indicate that insulin analogues are safe and effective, and therefore approved for children even from the age of 2 years. Moreover, suspicions and reports on the association of insulin analogues with carcinogenesis have not been established, requiring further investigation. This review reports the properties and characteristics of insulin analogues, as well as the results of current studies concerning pediatric patients with type 1 diabetes. Copyright 2012 Prous Science, S.A.U. or its licensors. All rights reserved.

Recent developments in naturally derived antimalarials: cryptolepine analogues.

PubMed

Wright, Colin W

2007-06-01

Increasing resistance of Plasmodium falciparum to commonly used antimalarial drugs has made the need for new agents increasingly urgent. In this paper, the potential of cryptolepine, an alkaloid from the West African shrub Cryptolepis sanguinolenta, as a lead towards new antimalarial agents is discussed. Several cryptolepine analogues have been synthesized that have promising in-vitro and in-vivo antimalarial activity. Studies on the antimalarial modes of action of these analogues indicate that they may have different or additional modes of action to the parent compound. Elucidation of the mode of action may facilitate the development of more potent antimalarial cryptolepine analogues.

The Most Important Recommended Times of Hand Washing with Soap and Water in Preventing the Occurrence of Acute Diarrhea Among Children Under Five Years of Age in Slums of Addis Ababa, Ethiopia.

PubMed

Adane, Metadel; Mengistie, Bezatu; Mulat, Worku; Medhin, Girmay; Kloos, Helmut

2018-04-01

Adequate hand washing with soap at five recommended times is particularly important in urban slums in developing countries, but which of the recommended times are the most important in the prevention of diarrhea among children under five years of age living in these areas remains unclear. To address this gap, a community-based cross-sectional study was undertaken in the slums of Addis Ababa, Ethiopia between September and November 2014. Data were collected using a pre-tested structured questionnaire and an observational checklist. Multivariable logistic regression with 95% confidence interval (CI) was used for data analysis. Only 4.4% of the households had hand washing facilities within or near a latrine with soap and water access. The average prevalence of hand washing with soap at the five recommended times was 19.8%. One quarter (24.8%) of caregivers washed their hands with soap before feeding a child, 23.8% before preparing food, and 17.1% after defecation. The most important recommended times in preventing acute diarrhea were before preparing food [adjusted odds ratio (AOR) 0.2; 95% CI 0.1-0.7] and after defecation (AOR 0.3; 95% CI 0.1-0.9). Household size of six or more persons (AOR 2.3; 95% CI 1.4-3.9) and low monthly household income (AOR 2.4; 95% CI 1.4-4.0) were significantly associated with acute diarrhea. Promoting hand washing with soap and advocacy programs at the five recommended times, especially before preparing food and after defecation, and implementation of socioeconomic development programs targeting poor households are essential for increasing the prevalence of hand washing with soap and preventing acute diarrhea in the slums of Addis Ababa.

Cholecystokinin octapeptide analogues stable to brain proteolysis.

PubMed

Knight, M; Barone, P; Tamminga, C A; Steardo, L; Chase, T N

1985-01-01

Based on recent findings identifying the initial degradative cleavage of CCK-8 at the Met3-Gly4 bond by a metalloendopeptidase, two analogues of CCK-8 with D-Ala and D-Trp substitutions at the Gly4 position were synthesized as stable analogues. Their stability to proteolysis by brain membranes and their binding potency at central CCK receptors were quantified. Both peptides are stable to degradation by peptidases in cortical synaptic membrane preparations. The analogues are nearly equipotent to CCK-8 in their affinities for inhibition of 125I-CCK-33 binding to guinea pig cortical membranes. L-Ala and L-Trp substituted peptides were synthesized for comparison. Both these peptides are degraded by synaptic membranes and the L-Trp substituted peptide possesses a greatly reduced affinity for central CCK receptors. Therefore, the structure of CCK due to the D conformation of Gly is more capable of interacting with brain CCK receptors. Further conformational analysis will establish whether the stabilized structure is a beta-bend or a beta-turn. Since these peptides are highly potent and stable to brain proteolysis they may be useful as stable CCK analogues for in vivo application.

Data partitioning enables the use of standard SOAP Web Services in genome-scale workflows.

PubMed

Sztromwasser, Pawel; Puntervoll, Pål; Petersen, Kjell

2011-07-26

Biological databases and computational biology tools are provided by research groups around the world, and made accessible on the Web. Combining these resources is a common practice in bioinformatics, but integration of heterogeneous and often distributed tools and datasets can be challenging. To date, this challenge has been commonly addressed in a pragmatic way, by tedious and error-prone scripting. Recently however a more reliable technique has been identified and proposed as the platform that would tie together bioinformatics resources, namely Web Services. In the last decade the Web Services have spread wide in bioinformatics, and earned the title of recommended technology. However, in the era of high-throughput experimentation, a major concern regarding Web Services is their ability to handle large-scale data traffic. We propose a stream-like communication pattern for standard SOAP Web Services, that enables efficient flow of large data traffic between a workflow orchestrator and Web Services. We evaluated the data-partitioning strategy by comparing it with typical communication patterns on an example pipeline for genomic sequence annotation. The results show that data-partitioning lowers resource demands of services and increases their throughput, which in consequence allows to execute in-silico experiments on genome-scale, using standard SOAP Web Services and workflows. As a proof-of-principle we annotated an RNA-seq dataset using a plain BPEL workflow engine.

SOAP: A Tool for the Fast Computation of Photometry and Radial Velocity Induced by Stellar Spots

NASA Astrophysics Data System (ADS)

Boisse, I.; Bonfils, X.; Santos, N. C.; Figueira, P.

2013-04-01

Dark spots and bright plages are present on the surface of dwarf stars from spectral types F to M, even in their low-active phase (like the Sun). Their appearance and disappearance on the stellar photosphere, combined with the stellar rotation, may lead to errors and uncertainties in the characterization of planets both in radial velocity (RV) and photometry. Spot Oscillation and Planet (SOAP) is a tool offered to the community that enables to simulate spots and plages on rotating stars and computes their impact on RV and photometric measurements. This tool will help to understand the challenges related to the knowledge of stellar activity for the next decade: detect telluric planets in the habitable zone of their stars (from G to M dwarfs), understand the activity in the low-mass end of M dwarf (on which future projects, like SPIRou or CARMENES, will focus), limitation to the characterization of the exoplanetary atmosphere (from the ground or with Spitzer, JWST), search for planets around young stars. These can be simulated with SOAP in order to search for indices and corrections to the effect of activity.

Molecular Epidemiology of a Pseudomonas aeruginosa Hospital Outbreak Driven by a Contaminated Disinfectant-Soap Dispenser

PubMed Central

Lanini, Simone; D'Arezzo, Silvia; Puro, Vincenzo; Martini, Lorena; Imperi, Francesco; Piselli, Pierluca; Montanaro, Marco; Paoletti, Simonetta; Visca, Paolo; Ippolito, Giuseppe

2011-01-01

Background and Objective Pseudomonas aeruginosa infection represents a main cause of morbidity and mortality among immunocompromised patients. This study describes a fatal epidemic of P. aeruginosa that occurred in a hematology unit in Italy. Methods Retrospective cohort study, prospective surveillance, auditing, extensive testing on healthcare workers and environmental investigation were performed to define the dynamics and potential causes of transmission. RAPD, macrorestriction analyses and sequence typing were used to define relationships between P. aeruginosa isolates. Results Eighteen cases of infection were identified in the different phases of the investigation. Of these, five constitute a significant molecular cluster of infection. A P. aeruginosa strain with the same genetic fingerprint and sequence type (ST175) as clinical isolates strain was also isolated from a heavily contaminated triclosan soap dispenser. Discussion and Conclusions Our results are consistent with the hypothesis that patients became indirectly infected, e.g., during central venous catheter handling through contaminated items, and that the triclosan soap dispenser acted as a common continuous source of P. aeruginosa infection. Since P. aeruginosa is intrinsically unsusceptible to triclosan, the use of triclosan-based disinfectant formulations should be avoided in those healthcare settings hosting patients at high risk of P. aeruginosa infection. PMID:21359222

Steric parameters, molecular modeling and hydropathic interaction analysis of the pharmacology of para-substituted methcathinone analogues

PubMed Central

Sakloth, F; Kolanos, R; Mosier, P D; Bonano, J S; Banks, M L; Partilla, J S; Baumann, M H; Negus, S S; Glennon, R A

2015-01-01

Background and Purpose There is growing concern over the abuse of certain psychostimulant methcathinone (MCAT) analogues. This study extends an initial quantitative structure–activity relationship (QSAR) investigation that demonstrated important steric considerations of seven 4- (or para-)substituted analogues of MCAT. Specifically, the steric character (Taft's steric ES) of the 4-position substituent affected in vitro potency to induce monoamine release via dopamine and 5-HT transporters (DAT and SERT) and in vivo modulation of intracranial self-stimulation (ICSS). Here, we have assessed the effects of other steric properties of the 4-position substituents. Experimental Approach Definitive steric parameters that more explicitly focus on the volume, width and length of the MCAT 4-position substituents were assessed. In addition, homology models of human DAT and human SERT based upon the crystallized Drosophila DAT were constructed and docking studies were performed, followed by hydropathic interaction (HINT) analysis of the docking results. Key Results The potency of seven MCAT analogues at DAT was negatively correlated with the volume and maximal width of their 4-position substituents, whereas potency at SERT increased as substituent volume and length increased. SERT/DAT selectivity, as well as abuse-related drug effects in the ICSS procedure, also correlated with the same parameters. Docking solutions offered a means of visualizing these findings. Conclusions and Implications These results suggest that steric aspects of the 4-position substituents of MCAT analogues are key determinants of their action and selectivity, and that the hydrophobic nature of these substituents is involved in their potency at SERT. PMID:25522019

Non-robust numerical simulations of analogue extension experiments

NASA Astrophysics Data System (ADS)

Naliboff, John; Buiter, Susanne

2016-04-01

Numerical and analogue models of lithospheric deformation provide significant insight into the tectonic processes that lead to specific structural and geophysical observations. As these two types of models contain distinct assumptions and tradeoffs, investigations drawing conclusions from both can reveal robust links between first-order processes and observations. Recent studies have focused on detailed comparisons between numerical and analogue experiments in both compressional and extensional tectonics, sometimes involving multiple lithospheric deformation codes and analogue setups. While such comparisons often show good agreement on first-order deformation styles, results frequently diverge on second-order structures, such as shear zone dip angles or spacing, and in certain cases even on first-order structures. Here, we present finite-element experiments that are designed to directly reproduce analogue "sandbox" extension experiments at the cm-scale. We use material properties and boundary conditions that are directly taken from analogue experiments and use a Drucker-Prager failure model to simulate shear zone formation in sand. We find that our numerical experiments are highly sensitive to numerous numerical parameters. For example, changes to the numerical resolution, velocity convergence parameters and elemental viscosity averaging commonly produce significant changes in first- and second-order structures accommodating deformation. The sensitivity of the numerical simulations to small parameter changes likely reflects a number of factors, including, but not limited to, high angles of internal friction assigned to sand, complex, unknown interactions between the brittle sand (used as an upper crust equivalent) and viscous silicone (lower crust), highly non-linear strain weakening processes and poor constraints on the cohesion of sand. Our numerical-analogue comparison is hampered by (a) an incomplete knowledge of the fine details of sand failure and sand

Women in Radio Soap Operas: A Historical Perspective of the Image of Women's "Sphere" in the "Golden Age."

ERIC Educational Resources Information Center

St John, Jacqueline

Radio's "Golden Age," the 1930s and 1940s produced numerous successful and profitable daytime serials, called "soap operas" because they were most often sponsored by firms selling laundry products. Among the most popular of these series were those produced by the team of Anne and Frank Hummert. Working through the…

Antibacterial Chemical Constituent and Antiseptic Herbal Soap from Salvinia auriculata Aubl.

PubMed Central

Lima, Samia; Diaz, Gaspar; Diaz, Marisa Alves Nogueira

2013-01-01

The bioassay-guided isolation of the active extract of Salvinia auriculata Aubl. led to the separation of three main compounds, characterized as stigmasterone, stigmasterol, and friedelinol. The pure form of diketosteroid presented a potential antibacterial activity with a minimum inhibitory concentration (MIC) value of 0.01 mg mL−1 against Staphylococcus aureus isolated from animals with mastitis infections. The active extract also showed a similar result to that previously obtained with pure diketosteroid when tested with the same isolates. The present study's results demonstrate the potential of this plant as an excipient for the production of antibacterial soaps aimed at controlling bovine mastitis infections, especially on small farms. PMID:24459530

Ke Wang, a Chinese television soap opera with a message.

PubMed

Wang, M; Singhal, A

1992-01-01

The Chinese soap opera, Ke Wang, was created by Li Xiaoming between August 1989 and June 1990 and produced at a cost of US$4650 per episode. The characters were drawn from everyday ordinary Chinese life: a traditional and open-minded and caring woman, a typical mother who works hard and loves her children, a highly educated upwardly mobile man who divorces his wife, a professor criticized during the Cultural Revolution, a doctor prejudiced against ordinary people, a kind honest man who marries the divorcee, a friend of the divorcee, a man who is optimistic in spite of bad experiences during the Cultural Revolution, and an excellent medical doctor who also resolves conflicts. The program was very popular, even among Communists, because of its value-based content, the real-life nature of the show, the change from highly restricted programming, the elaborate and supportive media coverage, and dialogue which closely matches audience preferences. The show has been aired by over 100 stations to date and has reached a total estimated audience of 550 million. The sale of television sets has increased since the show's appearance. The script reflects the conflicts between traditional and modern Chinese values. Pro-social values and behaviors are learned from the role models depicted; examples are given of immediate social impact. Ke Wang was a by-product of the Beijing Television Arts Center's interest in designing television programs that are relevant to the lives of ordinary people. The 60-minute scripts dealt with issues such as the status of women, social morality, family harmony, class conflict, responsible parenthood, maintenance of traditional culture, volunteerism, child development, and coping with physical disability. The Chinese government hailed Ke Wang as model television and awarded US$20,000 in prize money to the producers. The Chinese government is planning to produce other entertainment-education soap operas, which raises the problem of blatant, political

Intermittency in 2D soap film turbulence

NASA Astrophysics Data System (ADS)

Cerbus, R. T.; Goldburg, W. I.

2013-10-01

The Reynolds number dependency of intermittency for 2D turbulence is studied in a flowing soap film. The Reynolds number used here is the Taylor microscale Reynolds number Rλ, which ranges from 20 to 800. Strong intermittency is found for both the inverse energy and direct enstrophy cascades as measured by (a) the pdf of velocity differences P(δu(r)) at inertial scales r, (b) the kurtosis of P(∂xu), and (c) the scaling of the so-called intermittency exponent μ, which is zero if intermittency is absent. Measures (b) and (c) are quantitative, while (a) is qualitative. These measurements are in disagreement with some previous results but not all. The velocity derivatives are nongaussian at all Rλ but show signs of becoming gaussian as Rλ increases beyond the largest values that could be reached. The kurtosis of P(δu(r)) at various r indicates that the intermittency is scale dependent. The structure function scaling exponents also deviate strongly from the Kraichnan prediction. For the enstrophy cascade, the intermittency decreases as a power law in Rλ. This study suggests the need for a new look at the statistics of 2D turbulence.

SOAP and the Interstellar Froth

NASA Astrophysics Data System (ADS)

Tüllmann, R.; Rosa, M. R.; Dettmar, R.-J.

2005-06-01

We investigate whether the alleged failure of standard photoionization codes to match the Diffuse Ionized Gas (DIG) is simply caused by geometrical effects and the insufficient treatment of the radiative transfer. Standard photoionization models are applicable only to homogeneous and spherically symmetric nebulae with central ionizing stars, whereas the geometry of disk galaxies requires a 3D distribution of ionizing sources in the disk which illuminate the halo. This change in geometry together with a proper radiative transfer model is expected to substantially influence ionization conditions. Therefore, we developed a new and sophisticated 3D Monte Carlo photoionization code, called SOAP (Simulations Of Astrophysical Plasmas), by adapting an existing 1D code for HII-regions tep*{och} such, that it self-consistently models a 3D disk galaxy with a gaseous DIG halo. First results from a simple (dust-free) model with exponentially decreasing gas densities are presented and the predicted ionization structure of disk and halo are discussed. Theoretical line ratios agree well with observed ones, e.g,. for the halo of NGC 891. Moreover, the fraction of ionizing photons leaving the halo of the galaxy is plotted as a function of varying gas densities. This quantity will be of particular importance for forthcoming studies, because rough estimates indicate that about 7% of ionizing photons escape from the halo and contribute to the ionization of the IGM. Given the relatively large number density of normal spiral galaxies, OB-stars could have a much stronger impact on the ionization of the IGM than AGN or QSOs.

Controlling of N-alkylpolyamine analogue metabolism by selective deuteration.

PubMed

Ucal, Sebahat; Häkkinen, Merja R; Alanne, Aino-Liisa; Alhonen, Leena; Vepsäläinen, Jouko; Keinänen, Tuomo A; Hyvönen, Mervi T

2018-02-14

Replacing protium with deuterium is an efficient method to modulate drug metabolism. N -alkylated polyamine analogues are polyamine antimetabolites with proven anticancer efficacy. We have characterized earlier the preferred metabolic routes of N 1 , N 12 -diethylspermine (DESpm), N 1 -benzyl- N 12 -ethylspermine (BnEtSpm) and N 1 , N 12 -dibenzylspermine (DBSpm) by human recombinant spermine oxidase (SMOX) and acetylpolyamine oxidase (APAO). Here, we studied the above analogues, their variably deuterated counterparts and their metabolites as substrates and inhibitors of APAO, SMOX, semicarbazide-sensitive amine oxidase (SSAO), diamine oxidase (DAO) and monoamine oxidases. We found that targeted deuteration efficiently redirected the preferable cleavage site and suppressed reaction rate by APAO and SMOX in vitro We found a three- to six-fold decline in V max with moderate variable effect on K m when deuterium was located at the preferred hydrogen abstraction site of the analogue. We also found some of the metabolites to be potent inhibitors of DAO and SSAO. Surprisingly, analogue deuteration did not markedly alter the anti-proliferative efficacy of the drugs in DU145 prostate cancer cells, while in mouse embryonic fibroblasts, which had higher basal APAO and SMOX activities, moderate effect was observed. Interestingly, the anti-proliferative efficacy of the analogues did not correlate with their ability to suppress polyamine biosynthetic enzymes, induce spermidine/spermine- N 1 -acetyltransferase or deplete intracellular polyamine levels, but correlated with their ability to induce SMOX. Our data show that selective deuteration of N -alkyl polyamine analogues enables metabolic switching, offering the means for selective generation of bioactive metabolites inhibiting, e.g. SSAO and DAO, thus setting a novel basis for in vivo studies of this class of analogues. © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

Assessing youth who sexually offended: the predictive validity of the ERASOR, J-SOAP-II, and YLS/CMI in a non-Western context.

PubMed

Chu, Chi Meng; Ng, Kynaston; Fong, June; Teoh, Jennifer

2012-04-01

Recent research suggested that the predictive validity of adult sexual offender risk assessment measures can be affected when used cross-culturally, but there is no published study on the predictive validity of risk assessment measures for youth who sexually offended in a non-Western context. This study compared the predictive validity of three youth risk assessment measures (i.e., the Estimate of Risk of Adolescent Sexual Offense Recidivism [ERASOR], the Juvenile Sex Offender Assessment Protocol-II [J-SOAP-II], and the Youth Level of Service/Case Management Inventory [YLS/CMI]) for sexual and nonviolent recidivism in a sample of 104 male youth who sexually offended within a Singaporean context (M (follow-up) = 1,637 days; SD (follow-up) = 491). Results showed that the ERASOR overall clinical rating and total score significantly predicted sexual recidivism but only the former significantly predicted time to sexual reoffense. All of the measures (i.e., the ERASOR overall clinical rating and total score, the J-SOAP-II total score, as well as the YLS/CMI) significantly predicted nonsexual recidivism and time to nonsexual reoffense for this sample of youth who sexually offended. Overall, the results suggest that the ERASOR appears to be suited for assessing youth who sexually offended in a non-Western context, but the J-SOAP-II and the YLS/CMI have limited utility for such a purpose.

Role of circulation in European heatwaves using flow analogues

NASA Astrophysics Data System (ADS)

Jézéquel, Aglaé; Yiou, Pascal; Radanovics, Sabine

2018-02-01

The intensity of European heatwaves is connected to specific synoptic atmospheric circulation. Given the relatively small number of observations, estimates of the connection between the circulation and temperature require ad hoc statistical methods. This can be achieved through the use of analogue methods, which allow to determine a distribution of temperature conditioned to the circulation. The computation of analogues depends on a few parameters. In this article, we evaluate the influence of the variable representing the circulation, the size of the domain of computation, the length of the dataset, and the number of analogues on the reconstituted temperature anomalies. We tested the sensitivity of the reconstitution of temperature to these parameters for four emblematic recent heatwaves: June 2003, August 2003, July 2006 and July 2015. The paper provides general guidelines for the use of flow analogues to investigate European summer heatwaves. We found that Z500 is better suited than SLP to simulate temperature anomalies, and that rather small domains lead to better reconstitutions. The dataset length has an important influence on the uncertainty. We conclude by a set of recommendations for an optimal use of analogues to probe European heatwaves.

Esterified Trehalose Analogues Protect Mammalian Cells from Heat Shock.

PubMed

Bragg, Jack T; D'Ambrosio, Hannah K; Smith, Timothy J; Gorka, Caroline A; Khan, Faraz A; Rose, Joshua T; Rouff, Andrew J; Fu, Terence S; Bisnett, Brittany J; Boyce, Michael; Khetan, Sudhir; Paulick, Margot G

2017-09-19

Trehalose is a disaccharide produced by many organisms to better enable them to survive environmental stresses, including heat, cold, desiccation, and reactive oxygen species. Mammalian cells do not naturally biosynthesize trehalose; however, when introduced into mammalian cells, trehalose provides protection from damage associated with freezing and drying. One of the major difficulties in using trehalose as a cellular protectant for mammalian cells is the delivery of this disaccharide into the intracellular environment; mammalian cell membranes are impermeable to the hydrophilic sugar trehalose. A panel of cell-permeable trehalose analogues, in which the hydrophilic hydroxyl groups of trehalose are masked as esters, have been synthesized and the ability of these analogues to load trehalose into mammalian cells has been evaluated. Two of these analogues deliver millimolar concentrations of free trehalose into a variety of mammalian cells. Critically, Jurkat cells incubated with these analogues show improved survival after heat shock, relative to untreated Jurkat cells. The method reported herein thus paves the way for the use of esterified analogues of trehalose as a facile means to deliver high concentrations of trehalose into mammalian cells for use as a cellular protectant. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Mechanism of degradation of 2'-deoxycytidine by formamide: implications for chemical DNA sequencing procedures.

PubMed

Saladino, R; Crestini, C; Mincione, E; Costanzo, G; Di Mauro, E; Negri, R

1997-11-01

We describe the reaction of formamide with 2'-deoxycytidine to give pyrimidine ring opening by nucleophilic addition on the electrophilic C(6) and C(4) positions. This information is confirmed by the analysis of the products of formamide attack on 2'-deoxycytidine, 5-methyl-2'-deoxycytidine, and 5-bromo-2'-deoxycytidine, residues when the latter are incorporated into oligonucleotides by DNA polymerase-driven polymerization and solid-phase phosphoramidite procedure. The increased sensitivity of 5-bromo-2'-deoxycytidine relative to that of 2'-deoxycytidine is pivotal for the improvement of the one-lane chemical DNA sequencing procedure based on the base-selective reaction of formamide with DNA. In many DNA sequencing cases it will in fact be possible to incorporate this base analogue into the DNA to be sequenced, thus providing a complete discrimination between its UV absorption signal and that of the thymidine residues. The wide spectrum of different sensitivities to formamide displayed by the 2'-deoxycytidine analogues solves, in the DNA single-lane chemical sequencing procedure, the possible source of errors due to low discrimination between C and T residues.

A SOAP Web Services Interface to ACE Data

NASA Astrophysics Data System (ADS)

Davis, A. J.; Hamell, G. R.

2005-05-01

Since early in 1998, NASA's Advanced Composition Explorer (ACE) spacecraft has provided continuous measurements of solar wind and energetic particle activity from L1, located approximately 0.01 AU sunward of Earth. ACE data from nine instruments are being used to measure and compare the elemental and isotopic composition of the solar corona, the nearby interstellar medium, and the Galaxy, and to study particle acceleration processes that occur in a wide range of environments. The spacecraft has enough fuel to stay in orbit about L1 until at least 2020. The ACE Science Center (ASC) provides access to ACE data, and performs level 1 and browse data processing for the science instruments. Available on-line are solar wind, solar energetic particle, and galactic cosmic ray intensity and composition data, as well as solar wind and magnetic field parameters on a variety of time scales. We describe our recent efforts to provide enhanced access to ACE data via a SOAP Web Services interface. The interface utilizes the Space Physics Archive Search and Extract (SPASE) dictionary, and will be compatible with emerging virtual observatories.

What is the mechanism of soap film entrainment?

PubMed

Saulnier, Laurie; Restagno, Frédéric; Delacotte, Jérôme; Langevin, Dominique; Rio, Emmanuelle

2011-11-15

Classical Frankel's law describes the formation of soap films and their evolution upon pulling, a model situation of film dynamics in foams (formation, rheology, and destabilization). With the purpose of relating film pulling to foam dynamics, we have built a new setup able to give an instantaneous measurement of film thickness, thus allowing us to determine film thickness profile during pulling. We found that only the lower part of the film is of uniform thickness and follows Frankel's law, provided the entrainment velocity is small. We show that this is due to confinement effects: there is not enough surfactant in the bulk to fully cover the newly created surfaces which results in immobile film surfaces. At large velocities, surfaces become mobile and then Frankel's law breaks down, leading to a faster drainage and thus to a nonstationary thickness at the bottom of the film. These findings should help in understanding the large dispersion of previous experimental data reported during the last 40 years and clarifying the pulling phenomenon of thin liquid films.

Cladribine Analogues via O6-(Benzotriazolyl) Derivatives of Guanine Nucleosides

PubMed Central

Satishkumar, Sakilam; Vuram, Prasanna K.; Relangi, Siva Subrahmanyam; Gurram, Venkateshwarlu; Zhou, Hong; Kreitman, Robert J.; Montemayor, Michelle M. Martínez; Yang, Lijia; Kaliyaperumal, Muralidharan; Sharma, Somesh; Pottabathini, Narender; Lakshman, Mahesh K.

2016-01-01

Cladribine, 2-chloro-2′-deoxyadenosine, is a highly efficacious clinically used nucleoside for the treatment of hairy cell leukemia. It is also being evaluated against other lymphoid malignancies and has been a molecule of interest for well over half a century. In continuation of our interest on the amide bond-activation in purine nucleosides via the use of (benzotriazol-1yl-oxy)tris(dimethylamino)phosphonium hexafluorophosphate, we have evaluated the use of O6-(benzotriazol-1-yl)-2′-deoxyguanosine as a potential precursor to cladribine and its analogues. These compounds, after appropriate deprotection, were assessed for their biological activities and the data are presented herein. Against hairy cell leukemia (HCL), T-cell lymphoma (TCL), and chronic lymphocytic leukemia (CLL) cladribine was the most active against all. The bromo analogue of cladribine showed comparable activity to the ribose analogue of cladribine against HCL, but was more active against TCL and CLL. The bromo ribo analogue of cladribine possessed activity, but was least active among the C6-NH2-containing compounds. Substitution with alkyl groups at the exocyclic amino group appears detrimental to activity, and only the C6 piperidinyl cladribine analogue demonstrated any activity. Against adenocarcinoma MDA-MB-231 cells, only cladribine and its ribose analogue were most active. PMID:26556315

Viscosity of particulate soap films: approaching the jamming of 2D capillary suspensions.

PubMed

Timounay, Yousra; Rouyer, Florence

2017-05-14

We compute the effective viscosity of particulate soap films thanks to local velocity fields obtained by Particle Image Velocimetry (PIV) during film retraction experiments. We identify the jamming of these 2D capillary suspensions at a critical particle surface fraction (≃0.84) where effective viscosity diverges. Pair correlation function and number of neighbors in contact or close to contact reveal the cohesive nature of this 2D capillary granular media. The experimental 2D dynamic viscosities can be predicted by a model considering viscous dissipation at the liquid interfaces induced by the motion of individual particles.

Analogues of luteinizing hormone-releasing hormone containing cytotoxic groups.

PubMed

Janáky, T; Juhász, A; Bajusz, S; Csernus, V; Srkalovic, G; Bokser, L; Milovanovic, S; Redding, T W; Rékási, Z; Nagy, A

1992-02-01

In an attempt to produce better cytotoxic analogues, chemotherapeutic antineoplastic radicals including an alkylating nitrogen mustard derivative of D-phenylalanine (D-melphalan), reactive cyclopropane, anthraquinone derivatives [2-(hydroxymethyl)anthraquinone and the anticancer antibiotic doxorubicin], and an antimetabolite (methotrexate) were coupled to suitably modified agonists and antagonists of luteinizing hormone-releasing hormone (LH-RH). Analogues with D-lysine6 and D-ornithine6 or N epsilon-(2,3-diaminopropionyl)-D-lysine and N delta-(2,3-diaminopropionyl)-D-ornithine were used as carriers for one or two cytotoxic moieties. The enhanced biological activities produced by the incorporation of D amino acids into position 6 of the agonistic analogues were further increased by the attachment of hydrophobic cytotoxic groups, resulting in compounds with 10-50 times higher activity than LH-RH. Most of the monosubstituted agonistic analogues showed high affinities for the membrane receptors of human breast cancer cells, while the receptor binding affinities of peptides containing two cytotoxic side chains were lower. Antagonistic carriers [Ac-D-Nal(2)1,D-Phe(4Cl)2,D-Trp3,Arg5,D-Lys6,D-Ala10] LH-RH [where Nal(2) is 3-(2-naphthyl)alanine], [Ac-D-Nal(2)1,D-Phe(4Cl)2,D-Trp3,Arg5,N epsilon-(2,3-diaminopropionyl)-D-Lys6,D-Ala10]LH-RH, and their D-Pal(3)3 homologs [Pal(3) is 3-(3-pyridyl)alanine] as well as [Ac-D-Nal(2)1,D-Phe(4Cl)2,D-Pal(3)3,Tyr5,N epsilon-(2,3-diamino-propionyl)-D-Lys6,D-Ala10]LH-RH were linked to cytotoxic compounds. The hybrid molecules inhibited ovulation in rats at doses of 10 micrograms and suppressed LH release in vitro. The receptor binding of cytotoxic analogues was decreased compared to the precursor peptides, although analogues with 2-(hydroxymethyl)anthraquinone hemiglutarate had high affinities. All of the cytotoxic analogues tested inhibited [3H]thymidine incorporation into DNA in cultures of human breast and prostate cancer cell lines

Analogues of luteinizing hormone-releasing hormone containing cytotoxic groups.

PubMed Central

Janáky, T; Juhász, A; Bajusz, S; Csernus, V; Srkalovic, G; Bokser, L; Milovanovic, S; Redding, T W; Rékási, Z; Nagy, A

1992-01-01

In an attempt to produce better cytotoxic analogues, chemotherapeutic antineoplastic radicals including an alkylating nitrogen mustard derivative of D-phenylalanine (D-melphalan), reactive cyclopropane, anthraquinone derivatives [2-(hydroxymethyl)anthraquinone and the anticancer antibiotic doxorubicin], and an antimetabolite (methotrexate) were coupled to suitably modified agonists and antagonists of luteinizing hormone-releasing hormone (LH-RH). Analogues with D-lysine6 and D-ornithine6 or N epsilon-(2,3-diaminopropionyl)-D-lysine and N delta-(2,3-diaminopropionyl)-D-ornithine were used as carriers for one or two cytotoxic moieties. The enhanced biological activities produced by the incorporation of D amino acids into position 6 of the agonistic analogues were further increased by the attachment of hydrophobic cytotoxic groups, resulting in compounds with 10-50 times higher activity than LH-RH. Most of the monosubstituted agonistic analogues showed high affinities for the membrane receptors of human breast cancer cells, while the receptor binding affinities of peptides containing two cytotoxic side chains were lower. Antagonistic carriers [Ac-D-Nal(2)1,D-Phe(4Cl)2,D-Trp3,Arg5,D-Lys6,D-Ala10] LH-RH [where Nal(2) is 3-(2-naphthyl)alanine], [Ac-D-Nal(2)1,D-Phe(4Cl)2,D-Trp3,Arg5,N epsilon-(2,3-diaminopropionyl)-D-Lys6,D-Ala10]LH-RH, and their D-Pal(3)3 homologs [Pal(3) is 3-(3-pyridyl)alanine] as well as [Ac-D-Nal(2)1,D-Phe(4Cl)2,D-Pal(3)3,Tyr5,N epsilon-(2,3-diamino-propionyl)-D-Lys6,D-Ala10]LH-RH were linked to cytotoxic compounds. The hybrid molecules inhibited ovulation in rats at doses of 10 micrograms and suppressed LH release in vitro. The receptor binding of cytotoxic analogues was decreased compared to the precursor peptides, although analogues with 2-(hydroxymethyl)anthraquinone hemiglutarate had high affinities. All of the cytotoxic analogues tested inhibited [3H]thymidine incorporation into DNA in cultures of human breast and prostate cancer cell lines

Comparison of incident air kerma (ki) of common digital and analog radiology procedures in Kohgiluyeh and Boyer-Ahmad province

NASA Astrophysics Data System (ADS)

Vafapour, Hassan; Salehi, Zaker

2018-03-01

Introduction: Although in many developed countries, Analog radiography (AR) is replaced with digital radiography (DR) but AR is still widely used in many countries included Iran. Therefore, dosimetrically assessment of delivered dose is very important to avoid unnecessary patient dose. Materials and Methods: In this study, all imaging centers in Kohgiluyeh and Boyer-Ahmad were selected. The initial information included the mean kVp and mAs used by the personnel to perform each radiological procedure were gathered through a questionnaire. Barracuda dosimeter was then used to measure Incident air kerma (ki). Data obtained from digital radiography (DR) and analogue radiography (AR) were then analyzed and compared to each other. Results: The mean incident air kerma (ki) for five radiological procedures (chest AP&Lat, Skull AP&Lat, Lumbar spine AP&Lat, Thoracic spine AP&Lat and Pelvis) in digital devices were 0.38&1.34, 2.1&1.94, 4.99&7.83, 4.18& 6.41 and 4.33 mGy and those for analogue devices were 0.7&1.28, 3.05&3.02, 7.25&9.9, 7.125&8.36 and 5.36 mGy, respectively. Discussion and Conclusion: The use of low kVp or high mAs is one of the reasons to increase the incident air kerma (ki) in analogue methods comparing to digital methods in all procedures except the chest (in Lateral view). Also the results, surprisingly, showed that in some of the analogue methods incident air kerma (ki) was less than digital methods which is most probably because of the auto-exposure conditions.

Psychosocial Factors Mediating the Effect of the CHoBI7 Intervention on Handwashing with Soap: A Randomized Controlled Trial

ERIC Educational Resources Information Center

George, Christine Marie; Biswas, Shwapon; Jung, Danielle; Perin, Jamie; Parvin, Tahmina; Monira, Shirajum; Saif-Ur-Rahman, K. M.; Rashid, Mahamud-ur; Bhuyian, Sazzadul Islam; Thomas, Elizabeth D.; Dreibelbis, Robert; Begum, Farzana; Zohura, Fatema; Zhang, Xiaotong; Sack, David A.; Alam, Munirul; Sack, R. Bradley; Leontsini, Elli; Winch, Peter J.

2017-01-01

Inadequate hand hygiene is estimated to result in nearly 300,000 deaths annually, with the majority of deaths being among children younger than 5 years. In an effort to promote handwashing with soap and water treatment behaviors among highly susceptible household members of cholera patients, we recently developed the Cholera-Hospital-Based…

Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues

PubMed Central

Hager, Anastasia; Wu, Mingxuan; Wang, Huanchen; Brown, Nathaniel W.; Shears, Stephen B.

2016-01-01

The inositol pyrophosphate messengers (PP-InsPs) are emerging as an important class of cellular regulators. These molecules have been linked to numerous biological processes, including insulin secretion and cancer cell migration, but how they trigger such a wide range of cellular responses has remained unanswered in many cases. Here, we show that the PP-InsPs exhibit complex speciation behaviour and propose that a unique conformational switching mechanism could contribute to their multifunctional effects. We synthesised non-hydrolysable bisphosphonate analogues and crystallised the analogues in complex with mammalian PPIP5K2 kinase. Subsequently, the bisphosphonate analogues were used to investigate the protonation sequence, metal-coordination properties, and conformation in solution. Remarkably, the presence of potassium and magnesium ions enabled the analogues to adopt two different conformations near physiological pH. Understanding how the intrinsic chemical properties of the PP-InsPs can contribute to their complex signalling outputs will be essential to elucidate their regulatory functions. PMID:27460418

Use of Modified SOAP Notes and Peer-Led Small-Group Discussion in a Medical Physiology Course: Addressing the Hidden Curriculum

ERIC Educational Resources Information Center

Kibble, Jonathan; Hansen, Penelope A.; Nelson, Loren

2006-01-01

Peer leading of small-group discussion of cases; use of modified subjective, objective, assessment of physiology (SOAP) notes; and opportunities for self-assessment were introduced into a Medical Physiology course to increase students' awareness and practice of professional behaviors. These changes arose from faculty members' understanding of the…

[Cloning, expressing of exendin-4 analogue and bioactivity analysis in vivo].

PubMed

Li, Taiming; Gu, Chunjiao; Ge, Xiaoyu; Li, Zhezhe; Wang, Dan; Ma, Yanhong; Liu, Tao; Zhang, Meiyou; Li, Li; Liu, Jingjing

2012-07-01

To construct, express and purify Exendin-4 analogue and detect its biological activity in vivo. Insert gene sequence into fusion partner ofpED plasmid which is helped to purification, entitled the new recombinant plasmid 5 Exendin-4 analogue polypeptide gene and fusion partner gene was linked by acid hydrolysisgene, transformed to E. coli BL21 and the fusion protein was induced by lactose. After acid hydrolysis, the Exendin-4 analogue polypeptide separated from fusion chaperon. Anion charge chromatography were used to further purification. 6 to 8 week-old ICR mice were injected (s.c) with Exendin-4 analogue, blood glucose and plasma insulin level was detected in different period after oral glucose tolerance test. The results show that high expression of inclusion body was induced by lactose, which accounted for 40% of germ proteins, the Exendin-4 analogue was obtained with the purity of 91.8% after being purified by anion charge chromatography. Bioactivity assay showed that the level of blood glucose of mouse which treated with exendin-4 analogue was obviously decreased to normal (P < 0.01), and the level of plasma insulin was increased obviously (P < 0.01).

Vortex wakes of a flapping foil in a flowing soap film

NASA Astrophysics Data System (ADS)

Schnipper, Teis; Andersen, Anders; Bohr, Tomas

2008-11-01

We present an experimental study of an oscillating, symmetric foil in a vertically flowing soap film. By varying frequency and amplitude of the oscillation we explore and visualize a variety of wake structures, including von Kármán wake, reverse von Kármán wake, 2P wake, and 2P+2S wake. We characterize the transition from the von Kármán wake (drag) to the reverse von Kármán wake (thrust) and discuss the results in relation to fish swimming. We visualize the time evolution of the vortex shedding in detail, identify the origins of the vortices comprising the wake, and propose a simple model to account for the transition from von Kármán like wakes to more exotic wake structures.

Accessing SDO data in a pipeline environment using the VSO WSDL/SOAP interface

NASA Astrophysics Data System (ADS)

Suarez Sola, F. I.; Hourcle, J. A.; Amezcua, A.; Bogart, R.; Davey, A. R.; Gurman, J. B.; Hill, F.; Hughitt, V. K.; Martens, P. C.; Spencer, J.; Vso Team

2010-12-01

As part of the Virtual Solar Observatory (VSO) effort to support the Solar Dynamics Observatory (SDO) data, the VSO has worked on bringing up to date its WSDL document and SOAP interface to make it compatible with most widely used web services core engines. (E.g. axis2, jws, etc.) In this presentation we will explore the possibilities available for searching and/or fetching data within pipeline code. We will explain some of the WSDL/VSO-SDO interface intricacies and show how the vast amount of data that is available via the VSO can be tapped via IDL, Java, Perl or C in an uncomplicated way.

How does a soap film burst during generation?

NASA Astrophysics Data System (ADS)

Rio, Emmanuelle; Saulnier, Laurie; Restagno, Frederic; Langevin, Dominique

2011-11-01

Foams are dispersions of bubbles in a liquid matrix in the presence of stabilizing surfactants. Even if foams are ubiquitous, the ability of a solution to create a certain foam quantity is still not fully understood. As a first step, we choose to work on a simplified system and studied the stability of a soap film during its generation. We have built an experiment, in which we determine simultaneously the velocity of a frame pulled out of a soapy solution and the entire shape of the liquid film. We found that the film is made of two parts: the bottom part is of uniform and stationary thickness, well described by the classical Frankel's law; in the top part, the film drains until a black film appears near the frame upper boundary frame, and then bursts. In this study, we characterize both part of the films and show that the Frankel law breaks down at high capillary number due to surfactants confinement. We also explain why films pulled at high velocity have a shorter lifetime than those pulled at low velocity. L. Saulnier is funded by CNES.

Metric optimisation for analogue forecasting by simulated annealing

NASA Astrophysics Data System (ADS)

Bliefernicht, J.; Bárdossy, A.

2009-04-01

It is well known that weather patterns tend to recur from time to time. This property of the atmosphere is used by analogue forecasting techniques. They have a long history in weather forecasting and there are many applications predicting hydrological variables at the local scale for different lead times. The basic idea of the technique is to identify past weather situations which are similar (analogue) to the predicted one and to take the local conditions of the analogues as forecast. But the forecast performance of the analogue method depends on user-defined criteria like the choice of the distance function and the size of the predictor domain. In this study we propose a new methodology of optimising both criteria by minimising the forecast error with simulated annealing. The performance of the methodology is demonstrated for the probability forecast of daily areal precipitation. It is compared with a traditional analogue forecasting algorithm, which is used operational as an element of a hydrological forecasting system. The study is performed for several meso-scale catchments located in the Rhine basin in Germany. The methodology is validated by a jack-knife method in a perfect prognosis framework for a period of 48 years (1958-2005). The predictor variables are derived from the NCEP/NCAR reanalysis data set. The Brier skill score and the economic value are determined to evaluate the forecast skill and value of the technique. In this presentation we will present the concept of the optimisation algorithm and the outcome of the comparison. It will be also demonstrated how a decision maker should apply a probability forecast to maximise the economic benefit from it.

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues.

PubMed

Meints, Lisa M; Poston, Anne W; Piligian, Brent F; Olson, Claire D; Badger, Katherine S; Woodruff, Peter J; Swarts, Benjamin M

2017-02-17

Chemically modified versions of trehalose, or trehalose analogues, have applications in biology, biotechnology, and pharmaceutical science, among other fields. For instance, trehalose analogues bearing detectable tags have been used to detect Mycobacterium tuberculosis and may have applications as tuberculosis diagnostic imaging agents. Hydrolytically stable versions of trehalose are also being pursued due to their potential for use as non-caloric sweeteners and bioprotective agents. Despite the appeal of this class of compounds for various applications, their potential remains unfulfilled due to the lack of a robust route for their production. Here, we report a detailed protocol for the rapid and efficient one-step biocatalytic synthesis of trehalose analogues that bypasses the problems associated with chemical synthesis. By utilizing the thermostable trehalose synthase (TreT) enzyme from Thermoproteus tenax, trehalose analogues can be generated in a single step from glucose analogues and uridine diphosphate glucose in high yield (up to quantitative conversion) in 15-60 min. A simple and rapid non-chromatographic purification protocol, which consists of spin dialysis and ion exchange, can deliver many trehalose analogues of known concentration in aqueous solution in as little as 45 min. In cases where unreacted glucose analogue still remains, chromatographic purification of the trehalose analogue product can be performed. Overall, this method provides a "green" biocatalytic platform for the expedited synthesis and purification of trehalose analogues that is efficient and accessible to non-chemists. To exemplify the applicability of this method, we describe a protocol for the synthesis, all-aqueous purification, and administration of a trehalose-based click chemistry probe to mycobacteria, all of which took less than 1 hour and enabled fluorescence detection of mycobacteria. In the future, we envision that, among other applications, this protocol may be applied to