Assessment of TRAC-PF1/MOD1 version 14. 3 using separate effects critical flow and blowdown experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spindler, B.; Pellissier, M.

1990-01-01

Independent assessment of the TRAC code was conducted at the Centre d'Etudes Nucleaires de Grenoble of the Commissariate a l'Energie Atomique (France) in the frame of the ICAP. This report presents the results of the assessment of TRAC-PF1/MOD1 version 14.3 using critical flow steady state tests (MOBY-DICK, SUPER-MOBY-DICK), and blowdown tests (CANON, SUPER-CANON, VERTICAL-CANON, MARVIKEN, OMEGA-TUBE, OMEGA-BUNDLE). This document, Volume 1, presents the text and tables from this assessment.

Assessment of TRAC-PF1/MOD1 Version 14. 3 using separate effects critical flow and blowdown experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spindler, B.; Pellissier, M.

1990-01-01

Independent assessment of the TRAC code was conducted at the Centre d'Etudes Nucleaires de Grenoble of the Commissariate a l'Energie Atomique (France) in the frame of the ICAP. This report presents the results of the assessment of TRAC-PF1/MOD1 version 14.3 using critical flow steady state tests (MOBY-DICK, SUPER-MOBY-DICK), and blowdown tests (CANON, SUPER-CANON, VERTICAL-CANON, MARVIKEN, OMEGA-TUBE, OMEGA-BUNDLE). This document, Volume 2, presents the experimental data and figures from the assessment.

Pretest and posttest calculations of Semiscale Test S-07-10D with the TRAC computer program. [PWR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duerre, K.H.; Cort, G.E.; Knight, T.D.

The Transient Reactor Analysis Code (TRAC) developed at the Los Alamos National Laboratory was used to predict the behavior of the small-break experiment designated Semiscale S-07-10D. This test simulates a 10 per cent communicative cold-leg break with delayed Emergency Core Coolant injection and blowdown of the broken-loop steam generator secondary. Both pretest calculations that incorporated measured initial conditions and posttest calculations that incorporated measured initial conditions and measured transient boundary conditions were completed. The posttest calculated parameters were generally between those obtained from pretest calculations and those from the test data. The results are strongly dependent on depressurization rate and,more » hence, on break flow.« less

Crowd Behavior Algorithm Development for COMBAT XXI

DTIC Science & Technology

2017-05-30

This study cost the Department of Defense approximately $176,000 expended by TRAC in Fiscal Years 15-17. Prepared on 30 May 2017 TRAC Project Code...modeling to study impacts of military operations in urban terrain. Impacts of crowds on military operations can include those lethality, mobility...de- pendent on the particular socio-economic, political, and cultural environment of the region being studied in the scenario. Our research has found

Technical Requirements Analysis and Control Systems (TRACS) Initial Operating Capability (IOC) documentation

NASA Technical Reports Server (NTRS)

Hammond, Dana P.

1991-01-01

The Technical Requirements Analysis and Control Systems (TRACS) software package is described. TRACS offers supplemental tools for the analysis, control, and interchange of project requirements. This package provides the fundamental capability to analyze and control requirements, serves a focal point for project requirements, and integrates a system that supports efficient and consistent operations. TRACS uses relational data base technology (ORACLE) in a stand alone or in a distributed environment that can be used to coordinate the activities required to support a project through its entire life cycle. TRACS uses a set of keyword and mouse driven screens (HyperCard) which imposes adherence through a controlled user interface. The user interface provides an interactive capability to interrogate the data base and to display or print project requirement information. TRACS has a limited report capability, but can be extended with PostScript conventions.

Long range targeting for space based rendezvous

NASA Technical Reports Server (NTRS)

Everett, Louis J.; Redfield, R. C.

1995-01-01

The work performed under this grant supported the Dexterous Flight Experiment one STS-62 The project required developing hardware and software for automating a TRAC sensor on orbit. The hardware developed by for the flight has been documented through standard NASA channels since it has to pass safety, environmental, and other issues. The software has not been documented previously, therefore, this report provides a software manual for the TRAC code developed for the grant.

TRAC-PF1/MOD1 pretest predictions of MIST experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyack, B.E.; Steiner, J.L.; Siebe, D.A.

Los Alamos National Laboratory is a participant in the Integral System Test (IST) program initiated in June 1983 to provide integral system test data on specific issues and phenomena relevant to post small-break loss-of-coolant accidents (SBLOCAs) in Babcock and Wilcox plant designs. The Multi-Loop Integral System Test (MIST) facility is the largest single component in the IST program. During Fiscal Year 1986, Los Alamos performed five MIST pretest analyses. The five experiments were chosen on the basis of their potential either to approach the facility limits or to challenge the predictive capability of the TRAC-PF1/MOD1 code. Three SBLOCA tests weremore » examined which included nominal test conditions, throttled auxiliary feedwater and asymmetric steam-generator cooldown, and reduced high-pressure-injection (HPI) capacity, respectively. Also analyzed were two ''feed-and-bleed'' cooling tests with reduced HPI and delayed HPI initiation. Results of the tests showed that the MIST facility limits would not be approached in the five tests considered. Early comparisons with preliminary test data indicate that the TRAC-PF1/MOD1 code is correctly calculating the dominant phenomena occurring in the MIST facility during the tests. Posttest analyses are planned to provide a quantitative assessment of the code's ability to predict MIST transients.« less

TRAC Innovative Visualization Techniques

DTIC Science & Technology

2016-11-14

Therefore, TRAC analysts need a way to analyze the effectiveness of their visualization design choices. Currently, TRAC does not have a methodology ...to analyze visualizations used to support an analysis story. Our research team developed a visualization design methodology to create effective...visualizations that support an analysis story. First, we based our methodology on the latest research on design thinking, cognitive learning, and

Fostering Team Awareness in Earth System Modeling Communities

NASA Astrophysics Data System (ADS)

Easterbrook, S. M.; Lawson, A.; Strong, S.

2009-12-01

Existing Global Climate Models are typically managed and controlled at a single site, with varied levels of participation by scientists outside the core lab. As these models evolve to encompass a wider set of earth systems, this central control of the modeling effort becomes a bottleneck. But such models cannot evolve to become fully distributed open source projects unless they address the imbalance in the availability of communication channels: scientists at the core site have access to regular face-to-face communication with one another, while those at remote sites have access to only a subset of these conversations - e.g. formally scheduled teleconferences and user meetings. Because of this imbalance, critical decision making can be hidden from many participants, their code contributions can interact in unanticipated ways, and the community loses awareness of who knows what. We have documented some of these problems in a field study at one climate modeling centre, and started to develop tools to overcome these problems. We report on one such tool, TracSNAP, which analyzes the social network of the scientists contributing code to the model by extracting the data in an existing project code repository. The tool presents the results of this analysis to modelers and model users in a number of ways: recommendation for who has expertise on particular code modules, suggestions for code sections that are related to files being worked on, and visualizations of team communication patterns. The tool is currently available as a plugin for the Trac bug tracking system.

Interactive web-based identification and visualization of transcript shared sequences.

PubMed

Azhir, Alaleh; Merino, Louis-Henri; Nauen, David W

2018-05-12

We have developed TraC (Transcript Consensus), a web-based tool for detecting and visualizing shared sequences among two or more mRNA transcripts such as splice variants. Results including exon-exon boundaries are returned in a highly intuitive, data-rich, interactive plot that permits users to explore the similarities and differences of multiple transcript sequences. The online tool (http://labs.pathology.jhu.edu/nauen/trac/) is free to use. The source code is freely available for download (https://github.com/nauenlab/TraC). Copyright © 2018 Elsevier Inc. All rights reserved.

An analytical study on excitation of nuclear-coupled thermal-hydraulic instability due to seismically induced resonance in BWR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hirano, Masashi

1997-07-01

This paper describes the results of a scoping study on seismically induced resonance of nuclear-coupled thermal-hydraulic instability in BWRs, which was conducted by using TRAC-BF1 within a framework of a point kinetics model. As a result of the analysis, it is shown that a reactivity insertion could occur accompanied by in-surge of coolant into the core resulted from the excitation of the nuclear-coupled instability by the external acceleration. In order to analyze this phenomenon more in detail, it is necessary to couple a thermal-hydraulic code with a three-dimensional nuclear kinetics code.

Posttest analysis of MIST Test 3109AA using TRAC-PF1/MOD1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steiner, J.L.; Siebe, D.A.; Boyack, B.E.

This document discusses a posttest calculation and analysis of Multi-loop Integral System Test (MIST) 3109AA as the nominal test for the MIST program. It is a test of a small-break loss-of-coolant accident (SBLOCA) with a scaled 10-cm{sup 2} break in the B1 cold leg. The test exhibited the major post-SBLOCA phenomena, as expected, including depressurization to saturation, intermittent and interrupted loop flow, boiler-condenser mode cooling, refill, and postrefill cooldown. Full high-pressure injection and auxiliary feedwater were available, reactor coolant pumps were not available, and reactor-vessel vent valves and guard heaters were automatically controlled. Constant level control in the steam-generator secondariesmore » was used after steam-generator secondary refill and symmetric steam-generator pressure control was used. We performed the calculation using TRAC-PF1/MODI. Agreement between test data and the calculation was generally reasonable. All major trends and phenomena were correctly predicted. It is believed that the correct conclusions about trends and phenomena will be reached if the code is used in similar applications.« less

Posttest analysis of MIST Test 3109AA using TRAC-PF1/MOD1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steiner, J.L.; Siebe, D.A.; Boyack, B.E.

This document discusses a posttest calculation and analysis of Multi-loop Integral System Test (MIST) 3109AA as the nominal test for the MIST program. It is a test of a small-break loss-of-coolant accident (SBLOCA) with a scaled 10-cm[sup 2] break in the B1 cold leg. The test exhibited the major post-SBLOCA phenomena, as expected, including depressurization to saturation, intermittent and interrupted loop flow, boiler-condenser mode cooling, refill, and postrefill cooldown. Full high-pressure injection and auxiliary feedwater were available, reactor coolant pumps were not available, and reactor-vessel vent valves and guard heaters were automatically controlled. Constant level control in the steam-generator secondariesmore » was used after steam-generator secondary refill and symmetric steam-generator pressure control was used. We performed the calculation using TRAC-PF1/MODI. Agreement between test data and the calculation was generally reasonable. All major trends and phenomena were correctly predicted. It is believed that the correct conclusions about trends and phenomena will be reached if the code is used in similar applications.« less

Analysis of internal flows relative to the space shuttle main engine

NASA Technical Reports Server (NTRS)

1987-01-01

Cooperative efforts between the Lockheed-Huntsville Computational Mechanics Group and the NASA-MSFC Computational Fluid Dynamics staff has resulted in improved capabilities for numerically simulating incompressible flows generic to the Space Shuttle Main Engine (SSME). A well established and documented CFD code was obtained, modified, and applied to laminar and turbulent flows of the type occurring in the SSME Hot Gas Manifold. The INS3D code was installed on the NASA-MSFC CRAY-XMP computer system and is currently being used by NASA engineers. Studies to perform a transient analysis of the FPB were conducted. The COBRA/TRAC code is recommended for simulating the transient flow of oxygen into the LOX manifold. Property data for modifying the code to represent LOX/GOX flow was collected. The ALFA code was developed and recommended for representing the transient combustion in the preburner. These two codes will couple through the transient boundary conditions to simulate the startup and/or shutdown of the fuel preburner. A study, NAS8-37461, is currently being conducted to implement this modeling effort.

TRAC-Monterey FY16 Work Program Development and Report of Research Elicitation

DTIC Science & Technology

2016-01-01

any changes to priorities or additional projects that require immediate research. Work Program; Research Elicitation Unclassified UU UU UU UU 35 MAJ...conduct analysis for the Army. 1 Marks, Chris, Nesbitt, Peter. TRAC FY14 Research Requirements Elicitation . Technical Report TRAC-M-TM-13-059. 700 Dyer... Requirements Elicitation Interviews Interview Guide: 1. Describe a research requirement in the areas of topics, techniques, and methodologies. 2

Reliability of a new 4th generation FloTrac algorithm to track cardiac output changes in patients receiving phenylephrine.

PubMed

Ji, Fuhai; Li, Jian; Fleming, Neal; Rose, David; Liu, Hong

2015-08-01

Phenylephrine is often used to treat intra-operative hypotension. Previous studies have shown that the FloTrac cardiac monitor may overestimate cardiac output (CO) changes following phenylephrine administration. A new algorithm (4th generation) has been developed to improve performance in this setting. We performed a prospective observational study to assess the effects of phenylephrine administration on CO values measured by the 3rd and 4th generation FloTrac algorithms. 54 patients were enrolled in this study. We used the Nexfin, a pulse contour method shown to be insensitive to vasopressor administration, as the reference method. Radial arterial pressures were recorded continuously in patients undergoing surgery. Phenylephrine administration times were documented. Arterial pressure recordings were subsequently analyzed offline using three different pulse contour analysis algorithms: FloTrac 3rd generation (G3), FloTrac 4th generation (G4), and Nexfin (nf). One minute of hemodynamic measurements was analyzed immediately before phenylephrine administration and then repeated when the mean arterial pressure peaked. A total of 157 (4.6 ± 3.2 per patient, range 1-15) paired sets of hemodynamic recordings were analyzed. Phenylephrine induced a significant increase in stroke volume (SV) and CO with the FloTrac G3, but not with FloTrac G4 or Nexfin algorithms. Agreement between FloTrac G3 and Nexfin was: 0.23 ± 1.19 l/min and concordance was 51.1%. In contrast, agreement between FloTrac G4 and Nexfin was: 0.19 ± 0.86 l/min and concordance was 87.2%. In conclusion, the pulse contour method of measuring CO, as implemented in FloTrac 4th generation algorithm, has significantly improved its ability to track the changes in CO induced by phenylephrine.

Accuracy and trending ability of the fourth-generation FloTrac/Vigileo System™ in patients undergoing abdominal aortic aneurysm surgery.

PubMed

Maeda, Takuma; Hattori, Kohshi; Sumiyoshi, Miho; Kanazawa, Hiroko; Ohnishi, Yoshihiko

2018-06-01

The fourth-generation FloTrac/Vigileo™ improved its algorithm to follow changes in systemic vascular resistance index (SVRI). This revision may improve the accuracy and trending ability of CI even in patients who undergo abdominal aortic aneurysm (AAA) surgery which cause drastic change of SVRI by aortic clamping. The purpose of this study is to elucidate the accuracy and trending ability of the fourth-generation FloTrac/Vigileo™ in patients with AAA surgery by comparing the FloTrac/Vigileo™-derived CI (CI FT ) with that measured by three-dimensional echocardiography (CI 3D ). Twenty-six patients undergoing elective AAA surgery were included in this study. CI FT and CI3 D were determined simultaneously in eight points including before and after aortic clamp. We used CI 3D as the reference method. In the Bland-Altman analysis, CI FT had a wide limit of agreement with CI 3D showing a percentage error of 46.7%. Subgroup analysis showed that the percentage error between CO 3D and CO FT was 56.3% in patients with cardiac index < 2.5 L/min/m 2 and 28.4% in patients with cardiac index ≥ 2.5 L/min/m 2 . SVRI was significantly higher in patients with cardiac index < 2.5 L/min/m 2 (1703 ± 330 vs. 2757 ± 798; p < 0.001). The tracking ability of fourth generation of FloTrac/Vigileo™ after aortic clamp was not clinically acceptable (26.9%). The degree of accuracy of the fourth-generation FloTrac/Vigileo™ in patients with AAA surgery was not acceptable. The tracking ability of the fourth-generation FloTrac/Vigileo™ after aortic clamp was below the acceptable limit.

Cross Service Fixed-Wing Cost Estimation

DTIC Science & Technology

2016-05-17

TRAC-M-TR-16-021 May 2016 Cross Service Fixed-Wing Cost Estimation TRADOC Analysis Center 700 Dyer Road Monterey, California 93943-0692 This study...Service Fixed-Wing Cost Estimation MAJ Jarrod S. Shingleton TRADOC Analysis Center 700 Dyer Road Monterey, California 93943-0692 DISTRIBUTION STATEMENT...Wing Cost Estimation MAJ Jarrod Shingleton 060312 TRADOC Analysis Center, TRAC-MTRY Naval Postgraduate School 700 Dyer Road Bldg 246 Monterey, CA 93943

Fluorescent sensors for activity and regulation of the nitrate transceptor CHL1/NRT1.1 and oligopeptide transporters

PubMed Central

Ho, Cheng-Hsun; Frommer, Wolf B

2014-01-01

To monitor nitrate and peptide transport activity in vivo, we converted the dual-affinity nitrate transceptor CHL1/NRT1.1/NPF6.3 and four related oligopeptide transporters PTR1, 2, 4, and 5 into fluorescence activity sensors (NiTrac1, PepTrac). Substrate addition to yeast expressing transporter fusions with yellow fluorescent protein and mCerulean triggered substrate-dependent donor quenching or resonance energy transfer. Fluorescence changes were nitrate/peptide-specific, respectively. Like CHL1, NiTrac1 had biphasic kinetics. Mutation of T101A eliminated high-affinity transport and blocked the fluorescence response to low nitrate. NiTrac was used for characterizing side chains considered important for substrate interaction, proton coupling, and regulation. We observed a striking correlation between transport activity and sensor output. Coexpression of NiTrac with known calcineurin-like proteins (CBL1, 9; CIPK23) and candidates identified in an interactome screen (CBL1, KT2, WNKinase 8) blocked NiTrac1 responses, demonstrating the suitability for in vivo analysis of activity and regulation. The new technology is applicable in plant and medical research. DOI: http://dx.doi.org/10.7554/eLife.01917.001 PMID:24623305

Data and animal management software for large-scale phenotype screening.

PubMed

Ching, Keith A; Cooke, Michael P; Tarantino, Lisa M; Lapp, Hilmar

2006-04-01

The mouse N-ethyl-N-nitrosourea (ENU) mutagenesis program at the Genomics Institute of the Novartis Research Foundation (GNF) uses MouseTRACS to analyze phenotype screens and manage animal husbandry. MouseTRACS is a Web-based laboratory informatics system that electronically records and organizes mouse colony operations, prints cage cards, tracks inventory, manages requests, and reports Institutional Animal Care and Use Committee (IACUC) protocol usage. For efficient phenotype screening, MouseTRACS identifies mutants, visualizes data, and maps mutations. It displays and integrates phenotype and genotype data using likelihood odds ratio (LOD) plots of genetic linkage between genotype and phenotype. More detailed mapping intervals show individual single nucleotide polymorphism (SNP) markers in the context of phenotype. In addition, dynamically generated pedigree diagrams and inventory reports linked to screening results summarize the inheritance pattern and the degree of penetrance. MouseTRACS displays screening data in tables and uses standard charts such as box plots, histograms, scatter plots, and customized charts looking at clustered mice or cross pedigree comparisons. In summary, MouseTRACS enables the efficient screening, analysis, and management of thousands of animals to find mutant mice and identify novel gene functions. MouseTRACS is available under an open source license at http://www.mousetracs.sourceforge.net.

Report On Stakeholders Analysis Fast-Trac Phase Iii Deliverables, #5 One Set Of Stakeholder Readings, #6. Final Version Of The Stakeholders? Questionnaire, #7. Stakeholders? Analysis Report

DOT National Transportation Integrated Search

1996-12-10

THIS STUDY WAS UNDERTAKEN TO IDENTIFY AND EVALUATE CRITERIA BY WHICH THE PUBLIC, AND CERTAIN STAKEHOLDER GROUPS WITHIN THE PUBLIC, WILL JUDGE THE MERITS OF THE FAST-TRAC SYSTEM. OVER A PERIOD OF TWO YEARS, THREE SURVEYS WERE CONDUCTED TO OBTAIN SPECI...

Study of the TRAC Airfoil Table Computational System

NASA Technical Reports Server (NTRS)

Hu, Hong

1999-01-01

The report documents the study of the application of the TRAC airfoil table computational package (TRACFOIL) to the prediction of 2D airfoil force and moment data over a wide range of angle of attack and Mach number. The TRACFOIL generates the standard C-81 airfoil table for input into rotorcraft comprehensive codes such as CAM- RAD. The existing TRACFOIL computer package is successfully modified to run on Digital alpha workstations and on Cray-C90 supercomputers. A step-by-step instruction for using the package on both computer platforms is provided. Application of the newer version of TRACFOIL is made for two airfoil sections. The C-81 data obtained using the TRACFOIL method are compared with those of wind-tunnel data and results are presented.

Incident Management, Fast-Trac, Phase Iib Deliverables, #20. The Model Analysis Report On The Benefits Of Scats In Alleviating The Impacts Of Incidents

DOT National Transportation Integrated Search

1996-01-01

FAST-TRAC : SELECTING THE MOST APPROPRIATE TRAFFIC CONTROL STRATEGY FOR INCIDENT CONGESTION MANAGEMENT CAN HAVE A MAJOR IMPACT ON THE EXTENT AND DURATION OF THE RESULTING CONGESTION. THIS RESEARCH INVESTIGATED THE EFFECTIVENESSES OF SEVERAL CONTRO...

The incremental value of troponin biomarkers in risk stratification of acute coronary syndromes: is the relationship multiplicative?

PubMed

Amin, Amit P; Nathan, Sandeep; Vassallo, Patricia; Calvin, James E

2009-05-20

To emphasize the importance of troponin in the context of a new score for risk stratifying acute coronary syndromes (ACS) patients. Although troponins have powerful prognostic value, current ACS scores do not fully capitalize this prognostic ability. Here, we weigh troponin status in a multiplicative manner to develop the TRACS score from previously published Rush score risk factors (RRF). 2,866 ACS patients (46.7% troponin positive) from 9 centers comprising the TRACS registry, were randomly split into derivation (n=1,422) and validation (n=1,444) cohorts. In the derivation sample, RRF sum was multiplied by 3 if troponins were positive to yield the TRACS score, which was grouped into five categories of 0-2, 3-5, 6-8, 9-11, 12-15 (multiples of 3). Predictive performance of this score to predict hospital death was ascertained in the validation sample. The TRACS score had ROC AUC of 0.71 in the validation cohort. Logistic regression, Kaplan-Meier analysis, likelihood-ratio and Bayesian Information Criterion (BIC) test indicated that weighing troponin status with 3 in the TRACS score improved the prediction of mortality. Hosmer-Lemeshow test indicated sound model fit. We demonstrate that weighing troponin as a multiple of 3 yields robust prognostication of hospital mortality in ACS patients, when used in the context of the TRACS score.

The Incremental Value of Troponin Biomarkers in Risk Stratification of Acute Coronary Syndromes: Is the Relationship Multiplicative?

PubMed Central

Amin, Amit P; Nathan, Sandeep; Vassallo, Patricia; Calvin, James E

2009-01-01

Structured Abstract Objective: To emphasize the importance of troponin in the context of a new score for risk stratifying acute coronary syndromes (ACS) patients. Although troponins have powerful prognostic value, current ACS scores do not fully capitalize this prognostic ability. Here, we weigh troponin status in a multiplicative manner to develop the TRACS score from previously published Rush score risk factors (RRF). Methods: 2,866 ACS patients (46.7% troponin positive) from 9 centers comprising the TRACS registry, were randomly split into derivation (n=1,422) and validation (n=1,444) cohorts. In the derivation sample, RRF sum was multiplied by 3 if troponins were positive to yield the TRACS score, which was grouped into five categories of 0-2, 3-5, 6-8, 9-11, 12-15 (multiples of 3). Predictive performance of this score to predict hospital death was ascertained in the validation sample. Results: The TRACS score had ROC AUC of 0.71 in the validation cohort. Logistic regression, Kaplan-Meier analysis, likelihood-ratio and Bayesian Information Criterion (BIC) test indicated that weighing troponin status with 3 in the TRACS score improved the prediction of mortality. Hosmer-Lemeshow test indicated sound model fit. Conclusions: We demonstrate that weighing troponin as a multiple of 3 yields robust prognostication of hospital mortality in ACS patients, when used in the context of the TRACS score. PMID:19557150

Analysis of PANDA Passive Containment Cooling Steady-State Tests with the Spectra Code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stempniewicz, Marek M

2000-07-15

Results of post test simulation of the PANDA passive containment cooling (PCC) steady-state tests (S-series tests), performed at the PANDA facility at the Paul Scherrer Institute, Switzerland, are presented. The simulation has been performed using the computer code SPECTRA, a thermal-hydraulic code, designed specifically for analyzing containment behavior of nuclear power plants.Results of the present calculations are compared to the measurement data as well as the results obtained earlier with the codes MELCOR, TRAC-BF1, and TRACG. The calculated PCC efficiencies are somewhat lower than the measured values. Similar underestimation of PCC efficiencies had been obtained in the past, with themore » other computer codes. To explain this difference, it is postulated that condensate coming into the tubes forms a stream of liquid in one or two tubes, leaving most of the tubes unaffected. The condensate entering the water box is assumed to fall down in the form of droplets. With these assumptions, the results calculated with SPECTRA are close to the experimental data.It is concluded that the SPECTRA code is a suitable tool for analyzing containments of advanced reactors, equipped with passive containment cooling systems.« less

Managing Information On Technical Requirements

NASA Technical Reports Server (NTRS)

Mauldin, Lemuel E., III; Hammond, Dana P.

1993-01-01

Technical Requirements Analysis and Control Systems/Initial Operating Capability (TRACS/IOC) computer program provides supplemental software tools for analysis, control, and interchange of project requirements so qualified project members have access to pertinent project information, even if in different locations. Enables users to analyze and control requirements, serves as focal point for project requirements, and integrates system supporting efficient and consistent operations. TRACS/IOC is HyperCard stack for use on Macintosh computers running HyperCard 1.2 or later and Oracle 1.2 or later.

Assessment of the TRACE Reactor Analysis Code Against Selected PANDA Transient Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zavisca, M.; Ghaderi, M.; Khatib-Rahbar, M.

2006-07-01

The TRACE (TRAC/RELAP Advanced Computational Engine) code is an advanced, best-estimate thermal-hydraulic program intended to simulate the transient behavior of light-water reactor systems, using a two-fluid (steam and water, with non-condensable gas), seven-equation representation of the conservation equations and flow-regime dependent constitutive relations in a component-based model with one-, two-, or three-dimensional elements, as well as solid heat structures and logical elements for the control system. The U.S. Nuclear Regulatory Commission is currently supporting the development of the TRACE code and its assessment against a variety of experimental data pertinent to existing and evolutionary reactor designs. This paper presents themore » results of TRACE post-test prediction of P-series of experiments (i.e., tests comprising the ISP-42 blind and open phases) conducted at the PANDA large-scale test facility in 1990's. These results show reasonable agreement with the reported test results, indicating good performance of the code and relevant underlying thermal-hydraulic and heat transfer models. (authors)« less

Financial Health of the Higher Education Sector: Financial Results and TRAC Outcomes 2013-14. Issues Paper 2015/07

ERIC Educational Resources Information Center

Higher Education Funding Council for England, 2015

2015-01-01

This report provides an overview of the financial health of the Higher Education Funding Council for England (HEFCE)-funded higher education sector in England. The analysis covers financial results for the academic year 2013-14, as submitted to HEFCE in December 2014, as well as the outcomes from the sector's Transparent Approach to Costing (TRAC)…

Conflict Prediction Through Geo-Spatial Interpolation of Radicalization in Syrian Social Media

DTIC Science & Technology

2015-09-24

TRAC-M-TM-15-031 September 2015 Conflict Prediction Through Geo-Spatial Interpolation of Radicalization in Syrian Social Media ...Spatial Interpolation of Radicalization in Syrian Social Media Authors MAJ Adam Haupt Dr. Camber Warren...Spatial Interpolation of Radicalization in Syrian Social 1RAC Project Code 060114 Media 6. AUTHOR(S) MAJ Haupt, Dr. Warren 7. PERFORMING OR

Posttest TRAC-PD2/MOD1 predictions for FLECHT SEASET test 31504. [PWR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Booker, C.P.

TRAC-PD2/MOD1 is a publicly released version of TRAC that is used primarily to analyze large-break loss-of-coolant accidents in pressurized-water reactors (PWRs). TRAC-PD2 can calculate, among other things, reflood phenomena. TRAC posttest predictions are compared with test 31504 reflood data from the Full-Length Emergency Core Heat Transfer (FLECHT) System Effects and Separate Effects Tests (SEASET) facility. A false top-down quench is predicted near the top of the core and the subcooling is underpredicted at the bottom of the core. However, the overall TRAC predictions are good, especially near the center of the core.

Posttest analysis of MIST Test 320201 using TRAC-PF1/MOD1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Siebe, D.A.; Steiner, J.L.; Boyack, B.E.

A posttest calculation and analysis of Multi-Loop Integral System Test 320201, a small-break loss-of-coolant accident (SBLOCA) test with a scaled 50-cm{sup 2} cold-leg pump discharge leak, has been completed and is reported herein. It was one in a series of tests, with leak size varied parametrically. Scaled leak sizes included 5, 10, (the nominal, Test 3109AA), and 50 cm{sub 2}. The test exhibited the major post-SBLOCA phenomena, as expected, including depressurization to saturation, interruption of loop flow, boiler-condenser mode cooling, refill, and postrefill cooldown. Full high-pressure injection and auxiliary feedwater were available, reactor coolant pumps were not available, and reactor-vesselmore » vent valves and guard heaters were automatically controlled. Constant level control in the steam-generator (SG) secondaries was used after SG-secondary refill; and symmetric SG pressure control was also used. The sequence of events seen in this test was similar to the sequence of events for much of the nominal test except that events occurred in a shorter time frame as the system inventory was reduced and the system depressurized at a faster rate. The calculation was performed using TRAC-PFL/MOD 1. Agreement between test data and the calculation was generally reasonable. All major trends and phenomena were correctly predicted. We believe that the correct conclusions about trends and phenomena will be reached if the code is used in similar applications.« less

Posttest analysis of MIST Test 320201 using TRAC-PF1/MOD1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Siebe, D.A.; Steiner, J.L.; Boyack, B.E.

A posttest calculation and analysis of Multi-Loop Integral System Test 320201, a small-break loss-of-coolant accident (SBLOCA) test with a scaled 50-cm[sup 2] cold-leg pump discharge leak, has been completed and is reported herein. It was one in a series of tests, with leak size varied parametrically. Scaled leak sizes included 5, 10, (the nominal, Test 3109AA), and 50 cm[sub 2]. The test exhibited the major post-SBLOCA phenomena, as expected, including depressurization to saturation, interruption of loop flow, boiler-condenser mode cooling, refill, and postrefill cooldown. Full high-pressure injection and auxiliary feedwater were available, reactor coolant pumps were not available, and reactor-vesselmore » vent valves and guard heaters were automatically controlled. Constant level control in the steam-generator (SG) secondaries was used after SG-secondary refill; and symmetric SG pressure control was also used. The sequence of events seen in this test was similar to the sequence of events for much of the nominal test except that events occurred in a shorter time frame as the system inventory was reduced and the system depressurized at a faster rate. The calculation was performed using TRAC-PFL/MOD 1. Agreement between test data and the calculation was generally reasonable. All major trends and phenomena were correctly predicted. We believe that the correct conclusions about trends and phenomena will be reached if the code is used in similar applications.« less

78 FR 26171 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-03

... be found at: http://www2.mar.dfo-mpo.gc.ca/science/trac/tsr.html . The 2012 TRAC noted that, in... the 2012 TRAC assessment can be found at: http://www2.mar.dfo-mpo.gc.ca/science/trac/tsr.html . The... available from the Northeast Fisheries Science Center (NEFSC) at: http://www.nefsc.noaa.gov/saw/saw55...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyack, B.E.; Steiner, J.L.; Harmony, S.C.

The PIUS advanced reactor is a 640-MWe pressurized water reactor developed by Asea Brown Boveri (ABB). A unique feature of the PIUS concept is the absence of mechanical control and shutdown rods. Reactivity is normally controlled by coolant boron concentration and the temperature of the moderator coolant. ABB submitted the PIUS design to the US Nuclear Regulatory Commission (NRC) for preapplication review, and Los Alamos supported the NRC`s review effort. Baseline analyses of small-break initiators at two locations were performed with the system neutronic and thermal-hydraulic analysis code TRAC-PF1/MOD2. In addition, sensitivity studies were performed to explore the robustness ofmore » the PIUS concept to severe off-normal conditions having a very low probability of occurrence.« less

76 FR 23644 - Solicitation of Nominations for Members of the Transit Rail Advisory Committee for Safety (TRACS)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-27

... augment the TRACS' existing knowledge base with professionals who have done academic research in the... TRACS. From that solicitation, 21 members were chosen, each representing a broad base of expertise...

Modeling Off-Nominal Recovery in NextGen Terminal-Area Operations

NASA Technical Reports Server (NTRS)

Callantine, Todd J.

2011-01-01

Robust schedule-based arrival management requires efficient recovery from off-nominal situations. This paper presents research on modeling off-nominal situations and plans for recovering from them using TRAC, a route/airspace design, fast-time simulation, and analysis tool for studying NextGen trajectory-based operations. The paper provides an overview of a schedule-based arrival-management concept and supporting controller tools, then describes TRAC implementations of methods for constructing off-nominal scenarios, generating trajectory options to meet scheduling constraints, and automatically producing recovery plans.

Posttest data analysis of FIST experimental TRAC-BD1/MOD1 power transient experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wheatley, P.D.; Wagner, K.C.

The FIST power transient test 6PMC2 was analyzed to further the understanding of the FIST facility and provide an assessment of TRAC-BD1/MOD1. FIST power transient 6PMC2 investigated the thermal-hydraulic response following inadvertent closure of the main steam isolation valve and the subsequent failure of the reactor to scram. Failure of the high pressure core spray system was also assumed, resulting in only the reactor core isolation cooling flow for inventory makeup during the transient. The experiment was a sensitivity study with relatively high core power and low makeup rates. This study provides one of the first opportunities to assess TRAC-BD1/MOD1more » under power transient and natural circulation conditions with data from a facility with prototypical BWR geometry. The power transient test was analyzed with emphasis on the following phenomena: (a) the system pressure response, (b) the natural circulation flows and rates, and (c) the heater rod cladding temperature response. Based on the results of this study, TRAC-BD1/MOD1 can be expected to calculate the thermal-hydraulic behavior of a BWR during a power transient.« less

Status of thermalhydraulic modelling and assessment: Open issues

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bestion, D.; Barre, F.

1997-07-01

This paper presents the status of the physical modelling in present codes used for Nuclear Reactor Thermalhydraulics (TRAC, RELAP 5, CATHARE, ATHLET,...) and attempts to list the unresolved or partially resolved issues. First, the capabilities and limitations of present codes are presented. They are mainly known from a synthesis of the assessment calculations performed for both separate effect tests and integral effect tests. It is also interesting to list all the assumptions and simplifications which were made in the establishment of the system of equations and of the constitutive relations. Many of the present limitations are associated to physical situationsmore » where these assumptions are not valid. Then, recommendations are proposed to extend the capabilities of these codes.« less

An evaluation of Delaware's DelTrac program : building an integrated transportation management system

DOT National Transportation Integrated Search

2004-06-01

The DelTrac deployment experience included both successes and unmet challenges. Programmatically, the DelTrac approach to managing ITS has been successful at creating a great deal of integration and cooperation between organizations at DelDOT. Stakeh...

Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio.

PubMed

Luukkonen, Jani; Pascual, Laia Mira; Patlaka, Christina; Lång, Pernilla; Turunen, Sanna; Halleen, Jussi; Nousiainen, Tomi; Valkealahti, Maarit; Tuukkanen, Juha; Andersson, Göran; Lehenkari, Petri

2017-01-01

Osteopontin (OPN) is an immunoregulatory protein which production increases in both rheumatoid arthritis (RA) and osteoarthritis (OA). Phosphorylated osteopontin (Phospho-OPN) is known to increase macrophage and osteoclast activation, this process is controlled by extracellular tartrate-resistant acid phosphatase (TRAcP), also a biomarker for RA. Here, we evaluated the phosphorylation status of OPN in RA and OA synovia, as well as its correlation with TRAcP isoforms. Synovial tissue and fluid were obtained from 24 RA (14 seropositive and 10 seronegative) and 24 OA patients. Western blotting was used to analyze the extent of OPN phosphorylation. TRAcP isoforms were measured in synovial fluid using ELISA; immunohistochemistry assessed the distribution of OPN and TRAcP expressing cells in the synovial tissue, especially distinguishing between the TRAcP isoforms. Full-length OPN was more phosphorylated in RA than in OA (p<0.05). The thrombin cleaved C-terminal end of OPN was also more phosphorylated in RA (p<0.05). RA patients had a lower concentration of TRAcP 5B and higher concentration of less active 5A in their synovial fluid compared to OA patients. The TRAcP 5B/5A ratio was decreased in RA and correlated negatively with the amount of phospho-OPN (p<0.05). TRAcP positive cells for both isoforms were found all along the synovial lining; OPN antibody staining was localized in the extracellular matrix. Our data suggests that in RA the synovial fluid contains insufficient amounts of TRAcP 5B which increase levels of the proinflammatory phospho-OPN. This may lead to increased macrophage and osteoclast activation, resulting in the increased local inflammation and bone resorption present in RA joints.

Generating realistic environments for cyber operations development, testing, and training

NASA Astrophysics Data System (ADS)

Berk, Vincent H.; Gregorio-de Souza, Ian; Murphy, John P.

2012-06-01

Training eective cyber operatives requires realistic network environments that incorporate the structural and social complexities representative of the real world. Network trac generators facilitate repeatable experiments for the development, training and testing of cyber operations. However, current network trac generators, ranging from simple load testers to complex frameworks, fail to capture the realism inherent in actual environments. In order to improve the realism of network trac generated by these systems, it is necessary to quantitatively measure the level of realism in generated trac with respect to the environment being mimicked. We categorize realism measures into statistical, content, and behavioral measurements, and propose various metrics that can be applied at each level to indicate how eectively the generated trac mimics the real world.

Comparison of two methods for cardiac output measurement in critically ill patients.

PubMed

Saraceni, E; Rossi, S; Persona, P; Dan, M; Rizzi, S; Meroni, M; Ori, C

2011-05-01

The aim of recent haemodynamic monitoring has been to obtain continuous and reliable measures of cardiac output (CO) and indices of preload responsiveness. Many of these methods are based on the arterial pressure waveform analysis. The aim of our study was to assess the accuracy of CO measurements obtained by FloTrac/Vigileo, software version 1.07 and the new version 1.10 (Edwards Lifesciences LLC, Irvine, CA, USA), compared with CO measurements obtained by bolus thermodilution by pulmonary artery catheterization (PAC) in the intensive care setting. In 21 critically ill patients (enrolled in two University Hospitals), requiring invasive haemodynamic monitoring, PAC and FloTrac/Vigileo transducers connected to the arterial pressure line were placed. Simultaneous measurements of CO by two methods (FloTrac/Vigileo and thermodilution) were obtained three times a day for 3 consecutive days, when possible. The level of concordance between the two methods was assessed by the procedure suggested by Bland and Altman. One hundred and forty-one pairs of measurements (provided by thermodilution and by both 1.07 and 1.10 FloTrac/Vigileo versions) were obtained in 21 patients (seven of them were trauma patients) with a mean (sd) age of 59 (16) yr. The Pearson product moment coefficient was 0.62 (P<0.001). The bias was -0.18 litre min(-1). The limits of agreement were 4.54 and -4.90 litre min(-1), respectively. Our data show a poor level of concordance between measures provided by the two methods. We found an underestimation of CO values measured with the 1.07 software version of FloTrac for supranormal values of CO. The new software (1.10) has been improved in order to correct this bias; however, its reliability is still poor. On the basis of our data, we can therefore conclude that both software versions of FloTrac/Vigileo did not still provide reliable estimation of CO in our intensive care unit setting.

SU-E-J-47: Comparison of Online Image Registrations of Varian TrueBeam Cone-Beam CT and BrainLab ExacTrac Imaging Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, J; Shi, W; Andrews, D

2015-06-15

Purpose To compare online image registrations of TrueBeam cone-beam CT (CBCT) and BrainLab ExacTrac imaging systems. Methods Tests were performed on a Varian TrueBeam STx linear accelerator (Version 2.0), which is integrated with a BrainLab ExacTrac imaging system (Version 6.0.5). The study was focused on comparing the online image registrations for translational shifts. A Rando head phantom was placed on treatment couch and immobilized with a BrainLab mask. The phantom was shifted by moving the couch translationally for 8 mm with a step size of 1 mm, in vertical, longitudinal, and lateral directions, respectively. At each location, the phantom wasmore » imaged with CBCT and ExacTrac x-ray. CBCT images were registered with TrueBeam and ExacTrac online registration algorithms, respectively. And ExacTrac x-ray image registrations were performed. Shifts calculated from different registrations were compared with nominal couch shifts. Results The averages and ranges of absolute differences between couch shifts and calculated phantom shifts obtained from ExacTrac x-ray registration, ExacTrac CBCT registration with default window, ExaxTrac CBCT registration with adjusted window (bone), Truebeam CBCT registration with bone window, and Truebeam CBCT registration with soft tissue window, were: 0.07 (0.02–0.14), 0.14 (0.01–0.35), 0.12 (0.02–0.28), 0.09 (0–0.20), and 0.06 (0–0.10) mm, in vertical direction; 0.06 (0.01–0.12), 0.27 (0.07–0.57), 0.23 (0.02–0.48), 0.04 (0–0.10), and 0.08 (0– 0.20) mm, in longitudinal direction; 0.05 (0.01–0.21), 0.35 (0.14–0.80), 0.25 (0.01–0.56), 0.19 (0–0.40), and 0.20 (0–0.40) mm, in lateral direction. Conclusion The shifts calculated from ExacTrac x-ray and TrueBeam CBCT registrations were close to each other (the differences between were less than 0.40 mm in any direction), and had better agreements with couch shifts than those from ExacTrac CBCT registrations. There were no significant differences between TrueBeam CBCT registrations using different windows. In ExacTrac CBCT registrations, using bone window led to better agreements than using default window.« less

Market Assessment For Traveler Services, A Choice Modeling Study Phase Iii, Fast-Trac Deliverable, #16B: Final Choice Modeling Report

DOT National Transportation Integrated Search

1999-02-12

FAST-TRAC : THIS REPORT DESCRIBES THE CHOICE MODEL STUDY OF THE FAST-TRAC (FASTER AND SAFER TRAVEL THROUGH TRAFFIC ROUTING AND ADVANCED CONTROLS) OPERATIONAL TEST IN SOUTHEAST MICHIGAN. CHOICE MODELING IS A STATED-PREFERENCE APPROACH IN WHICH RESP...

Self calibrating autoTRAC

NASA Technical Reports Server (NTRS)

Everett, Louis J.

1994-01-01

The work reported here demonstrates how to automatically compute the position and attitude of a targeting reflective alignment concept (TRAC) camera relative to the robot end effector. In the robotics literature this is known as the sensor registration problem. The registration problem is important to solve if TRAC images need to be related to robot position. Previously, when TRAC operated on the end of a robot arm, the camera had to be precisely located at the correct orientation and position. If this location is in error, then the robot may not be able to grapple an object even though the TRAC sensor indicates it should. In addition, if the camera is significantly far from the alignment it is expected to be at, TRAC may give incorrect feedback for the control of the robot. A simple example is if the robot operator thinks the camera is right side up but the camera is actually upside down, the camera feedback will tell the operator to move in an incorrect direction. The automatic calibration algorithm requires the operator to translate and rotate the robot arbitrary amounts along (about) two coordinate directions. After the motion, the algorithm determines the transformation matrix from the robot end effector to the camera image plane. This report discusses the TRAC sensor registration problem.

Posttest data analysis and assessment of TRAC-BD1/MOD1 with data from a Full Integral Simulation Test (FIST) power transient experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wheatley, P.D.; Wagner, K.C.

The FIST power transient test 6PMC2 was analyzed to further the understanding of the FIST facility and provide an assessment of TRAC-BD1/MOD1. FIST power transient 6PMC2 investigated the thermal-hydraulic response following inadvertent closure of the main steam isolation valve and the subsequent failure of the reactor to scram. Failure of the high pressure core spray system was also assumed, resulting on only the reactor core isolation cooling flow for inventory makeup during the transient. The experiment was a sensitivity study with relatively high core power and low makeup rates. This study provides one of the first opportunities to assess TRAC-BD1/MOD1more » under power transient and natural circulation conditions with data from a facility with prototypical BWR geometry. The power transient test was analyzed with emphasis on the following phenomena; (a) the system pressure response, (b) the natural circulation flows and rates, and (c) the heater rod cladding temperature response. Based on the results of this study, TRAC-BD1/MOD1 can be expected to calculate the thermal-hydraulic behavior of a BWR during a power transient.« less

75 FR 11225 - Proposed Collection; Comment Request for Tip Reporting Alternative Commitment Agreement (TRAC...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-10

... Reporting Alternative Commitment Agreement (TRAC) for Use in Industries Other Than the Food and Beverage... Use in Industries Other Than the Food and Beverage Industry and the Cosmetology and Barber Industry... Alternative Commitment Agreement (TRAC) for Use in Industries Other Than the Food and Beverage Industry and...

75 FR 11226 - Proposed Collection; Comment Request for Tip Reporting Alternative Commitment Agreement (TRAC...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-10

... Reporting Alternative Commitment Agreement (TRAC) for Use in the Food and Beverage Industry AGENCY: Internal... Reporting Alternative Commitment Agreement (TRAC) for Use in the Food and Beverage Industry. DATES: Written... in the Food and Beverage Industry. OMB Number: 1545-1549. Abstract: Announcement 2000-22, 2000-19 I.R...

An integrated decision support system for TRAC: A proposal

NASA Technical Reports Server (NTRS)

Mukkamala, Ravi

1991-01-01

Optimal allocation and usage of resources is a key to effective management. Resources of concern to TRAC are: Manpower (PSY), Money (Travel, contracts), Computing, Data, Models, etc. Management activities of TRAC include: Planning, Programming, Tasking, Monitoring, Updating, and Coordinating. Existing systems are insufficient, not completely automated, manpower intensive, and has the potential for data inconsistency exists. A system is proposed which suggests a means to integrate all project management activities of TRAC through the development of a sophisticated software and by utilizing the existing computing systems and network resources. The systems integration proposal is examined in detail.

Williams with TRAC experiment in Destiny

NASA Image and Video Library

2007-03-08

ISS014-E-16215 (8 March 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, works with the Test of Reaction and Adaptation Capabilities (TRAC) experiment in the Destiny laboratory of the International Space Station. The TRAC investigation will test the theory of brain adaptation during space flight by testing hand-eye coordination before, during and after the space flight.

Williams with TRAC experiment in Destiny

NASA Image and Video Library

2007-03-08

ISS014-E-16210 (8 March 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, works with the Test of Reaction and Adaptation Capabilities (TRAC) experiment in the Destiny laboratory of the International Space Station. The TRAC investigation will test the theory of brain adaptation during space flight by testing hand-eye coordination before, during and after the space flight.

Williams with TRAC experiment in Destiny

NASA Image and Video Library

2007-03-08

ISS014-E-16214 (8 March 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, works with the Test of Reaction and Adaptation Capabilities (TRAC) experiment in the Destiny laboratory of the International Space Station. The TRAC investigation will test the theory of brain adaptation during space flight by testing hand-eye coordination before, during and after the space flight.

76 FR 32227 - Core Industries, Inc., DBA Star Trac and/or Unisen, Inc., DBA STAR TRAC and/or Trac Strength...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-03

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-75,192; TA-W-75,192A] Core... Leased Workers From Aerotek, Helpmates, Mattson, and Empire Staffing, Irvine, CA; Core Industries, Inc... Eligibility to Apply for Worker Adjustment Assistance on February 15, 2011, applicable to workers of Core...

Tyurin with TRAC experiment in Destiny laboratory

NASA Image and Video Library

2007-01-02

ISS014-E-11047 (2 Jan. 2007) --- Cosmonaut Mikhail Tyurin, Expedition 14 flight engineer representing Russia's Federal Space Agency, works with the Test of Reaction and Adaptation Capabilities (TRAC) experiment in the Destiny laboratory of the International Space Station. The TRAC investigation will test the theory of brain adaptation during space flight by testing hand-eye coordination before, during and after the space flight.

Lopez-Alegria with TRAC experiment in Destiny laboratory

NASA Image and Video Library

2007-01-02

ISS014-E-11061 (2 Jan. 2007) --- Astronaut Michael E. Lopez-Alegria, Expedition 14 commander and NASA space station science officer, works with the Test of Reaction and Adaptation Capabilities (TRAC) experiment in the Destiny laboratory of the International Space Station. The TRAC investigation will test the theory of brain adaptation during space flight by testing hand-eye coordination before, during and after the space flight.

SU-E-J-34: Setup Accuracy in Spine SBRT Using CBCT 6D Image Guidance in Comparison with 6D ExacTrac

DOE Office of Scientific and Technical Information (OSTI.GOV)

Han, Z; Yip, S; Lewis, J

2015-06-15

Purpose Volumetric information of the spine captured on CBCT can potentially improve the accuracy in spine SBRT setup that has been commonly performed through 2D radiographs. This work evaluates the setup accuracy in spine SBRT using 6D CBCT image guidance that recently became available on Varian systems. Methods ExacTrac radiographs have been commonly used for Spine SBRT setup. The setup process involves first positioning patients with lasers followed by localization imaging, registration, and repositioning. Verification images are then taken providing the residual errors (ExacTracRE) before beam on. CBCT verification is also acquired in our institute. The availability of both ExacTracmore » and CBCT verifications allows a comparison study. 41 verification CBCT of 16 patients were retrospectively registered with the planning CT enabling 6D corrections, giving CBCT residual errors (CBCTRE) which were compared with ExacTracRE. Results The RMS discrepancies between CBCTRE and ExacTracRE are 1.70mm, 1.66mm, 1.56mm in vertical, longitudinal and lateral directions and 0.27°, 0.49°, 0.35° in yaw, roll and pitch respectively. The corresponding mean discrepancies (and standard deviation) are 0.62mm (1.60mm), 0.00mm (1.68mm), −0.80mm (1.36mm) and 0.05° (0.58°), 0.11° (0.48°), −0.16° (0.32°). Of the 41 CBCT, 17 had high-Z surgical implants. No significant difference in ExacTrac-to-CBCT discrepancy was observed between patients with and without the implants. Conclusion Multiple factors can contribute to the discrepancies between CBCT and ExacTrac: 1) the imaging iso-centers of the two systems, while calibrated to coincide, can be different; 2) the ROI used for registration can be different especially if ribs were included in ExacTrac images; 3) small patient motion can occur between the two verification image acquisitions; 4) the algorithms can be different between CBCT (volumetric) and ExacTrac (radiographic) registrations.« less

SU-F-P-40: Analysis of Pelvic Lymph Node Margin Using Prostate Fiducial Markers, for SBRT Treatments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Torres, J; Castro Pena, P; Garrigo, E

2016-06-15

Purpose: The use of fiducials markers in prostate treatment allows a precise localization of this volume. Typical prostate SBRT margins with fiducials markers are 5mm in all directions, except toward the rectum, where 3mm is used. For some patients nearby pelvic lymph nodes with 5mm margin need to be irradiate assuming that its localization is linked to the prostate fiducial markers instead of bony anatomy. The purpose of this work was to analyze the geometric impact of locate the lymph node regions through the patient positioning by prostate fiducial markers. Methods: 10 patients with prostate SBRT with lymph nodes irradiationmore » were selected. Each patient had 5 implanted titanium fiducial markers. A Novalis TX (BrainLAB-Varian) with ExacTrac and aSi1000 portal image was used. Treatment plan uses 11 beams with a dose prescription (D95%) of 40Gy to the prostate and 25Gy to the lymph node in 5 fractions. Daily positioning was carried out by ExacTrac system based on the implanted fiducials as the reference treatment position; further position verification was performed using the ExacTrac and two portal images (gantry angle 0 and 90) based on bony structures. Comparison between reference position with bony based ExacTrac and portal image localization, was done for each treatment fraction Results: A total of 50 positioning analysis were done. The average discrepancy between reference treatment position and ExacTrac based on bony anatomy (pubic area) was 4.2mm [0.3; 11.2]. The discrepancy was <5mm in 61% of the cases and <9mm in 92%. Using portal images the average discrepancy was 3.7mm [0.0; 11.1]. The discrepancy was <5mm in 69% of the cases and <9mm in 96%. Conclusion: Localizing lymph node by prostate fiducial markers may produce large discrepancy as large as 11mm compared to bony based localization. Dosimetric impact of this discrepancy should be studied.« less

Simulation of Rotary-Wing Near-Wake Vortex Structures Using Navier-Stokes CFD Methods

NASA Technical Reports Server (NTRS)

Kenwright, David; Strawn, Roger; Ahmad, Jasim; Duque, Earl; Warmbrodt, William (Technical Monitor)

1997-01-01

This paper will use high-resolution Navier-Stokes computational fluid dynamics (CFD) simulations to model the near-wake vortex roll-up behind rotor blades. The locations and strengths of the trailing vortices will be determined from newly-developed visualization and analysis software tools applied to the CFD solutions. Computational results for rotor nearwake vortices will be used to study the near-wake vortex roll up for highly-twisted tiltrotor blades. These rotor blades typically have combinations of positive and negative spanwise loading and complex vortex wake interactions. Results of the computational studies will be compared to vortex-lattice wake models that are frequently used in rotorcraft comprehensive codes. Information from these comparisons will be used to improve the rotor wake models in the Tilt-Rotor Acoustic Code (TRAC) portion of NASA's Short Haul Civil Transport program (SHCT). Accurate modeling of the rotor wake is an important part of this program and crucial to the successful design of future civil tiltrotor aircraft. The rotor wake system plays an important role in blade-vortex interaction noise, a major problem for all rotorcraft including tiltrotors.

Summary of papers on current and anticipated uses of thermal-hydraulic codes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Caruso, R.

1997-07-01

The author reviews a range of recent papers which discuss possible uses and future development needs for thermal/hydraulic codes in the nuclear industry. From this review, eight common recommendations are extracted. They are: improve the user interface so that more people can use the code, so that models are easier and less expensive to prepare and maintain, and so that the results are scrutable; design the code so that it can easily be coupled to other codes, such as core physics, containment, fission product behaviour during severe accidents; improve the numerical methods to make the code more robust and especiallymore » faster running, particularly for low pressure transients; ensure that future code development includes assessment of code uncertainties as integral part of code verification and validation; provide extensive user guidelines or structure the code so that the `user effect` is minimized; include the capability to model multiple fluids (gas and liquid phase); design the code in a modular fashion so that new models can be added easily; provide the ability to include detailed or simplified component models; build on work previously done with other codes (RETRAN, RELAP, TRAC, CATHARE) and other code validation efforts (CSAU, CSNI SET and IET matrices).« less

Forrester works with the TRAC Experiment in the U.S Laboratory during Joint Operations

NASA Image and Video Library

2007-06-12

S117-E-07092 (12 June 2007) --- Astronaut Patrick Forrester, STS-117 mission specialist, works with the Test of Reaction and Adaptation Capabilities (TRAC) experiment in the Destiny laboratory of the International Space Station while Space Shuttle Atlantis was docked with the station. The TRAC investigation will test the theory of brain adaptation during space flight by testing hand-eye coordination before, during and after the space flight.

Anderson works with the TRAC experiment in the U.S. Laboratory during Joint Operations

NASA Image and Video Library

2007-06-12

S117-E-07031 (12 June 2007) --- Astronaut Clayton Anderson, Expedition 15 flight engineer, works with the Test of Reaction and Adaptation Capabilities (TRAC) experiment in the Destiny laboratory of the International Space Station while Space Shuttle Atlantis was docked with the station. The TRAC investigation will test the theory of brain adaptation during space flight by testing hand-eye coordination before, during and after the space flight.

Comparison of Online 6 Degree-of-Freedom Image Registration of Varian TrueBeam Cone-Beam CT and BrainLab ExacTrac X-Ray for Intracranial Radiosurgery.

PubMed

Li, Jun; Shi, Wenyin; Andrews, David; Werner-Wasik, Maria; Lu, Bo; Yu, Yan; Dicker, Adam; Liu, Haisong

2017-06-01

The study was aimed to compare online 6 degree-of-freedom image registrations of TrueBeam cone-beam computed tomography and BrainLab ExacTrac X-ray imaging systems for intracranial radiosurgery. Phantom and patient studies were performed on a Varian TrueBeam STx linear accelerator (version 2.5), which is integrated with a BrainLab ExacTrac imaging system (version 6.1.1). The phantom study was based on a Rando head phantom and was designed to evaluate isocenter location dependence of the image registrations. Ten isocenters at various locations representing clinical treatment sites were selected in the phantom. Cone-beam computed tomography and ExacTrac X-ray images were taken when the phantom was located at each isocenter. The patient study included 34 patients. Cone-beam computed tomography and ExacTrac X-ray images were taken at each patient's treatment position. The 6 degree-of-freedom image registrations were performed on cone-beam computed tomography and ExacTrac, and residual errors calculated from cone-beam computed tomography and ExacTrac were compared. In the phantom study, the average residual error differences (absolute values) between cone-beam computed tomography and ExacTrac image registrations were 0.17 ± 0.11 mm, 0.36 ± 0.20 mm, and 0.25 ± 0.11 mm in the vertical, longitudinal, and lateral directions, respectively. The average residual error differences in the rotation, roll, and pitch were 0.34° ± 0.08°, 0.13° ± 0.09°, and 0.12° ± 0.10°, respectively. In the patient study, the average residual error differences in the vertical, longitudinal, and lateral directions were 0.20 ± 0.16 mm, 0.30 ± 0.18 mm, 0.21 ± 0.18 mm, respectively. The average residual error differences in the rotation, roll, and pitch were 0.40°± 0.16°, 0.17° ± 0.13°, and 0.20° ± 0.14°, respectively. Overall, the average residual error differences were <0.4 mm in the translational directions and <0.5° in the rotational directions. ExacTrac X-ray image registration is comparable to TrueBeam cone-beam computed tomography image registration in intracranial treatments.

Epitope enhancement for immunohistochemical demonstration of tartrate-resistant acid phosphatase.

PubMed

Janckila, A J; Lear, S C; Martin, A W; Yam, L T

1996-03-01

We have developed a monoclonal antibody (9C5) for immunohistochemical localization of tartrate-resistant acid phosphatase (TRAcP). This antibody reacts with a denatured epitope of TRAcP and requires enhancement methods to promote antigenicity in paraffin-embedded tissues. We used this antibody to systematically examine proteolytic digestion and heat denaturation conditions for epitope enhancement in both paraffin sections and fixed smears. The goal was to increase the sensitivity of the immunohistochemical stain for TRAcP. Optimal conditions for proteolytic digestion were established. Denaturation in a conventional boiling water bath was compared to microwave irradiation in several commonly used solutions. Immunohistochemistry was compared directly to TRAcP cytochemistry in fixed smears from hairy cell leukemia specimens to gauge the level of sensitivity of our improved method. Attempts were made to "retrieve" the 9C5 epitope from overfixed tissues and aged smears. Maximal immunoreactivity of TRAcP was achieved by microwave irradiation in a citrate or Tris buffer of pH 6.0-8.0 without the need for a subsequent protease digestion step. With this method of epitope enhancement, immunohistochemistry with antibody 9C5 was as sensitive as direct cytochemical staining of TRAcP activity. However, once a tissue specimen had been overfixed or a smear stored for a year or more, the 9C5 epitope was no longer retrievable. The key element in epitope enhancement for 9C5 immunohistochemistry is heat denaturation of the target epitope. Immunohistochemistry of TRAcP in paraffin sections would be a great asset to the study of specialized forms of the monocyte/macrophage lineage and to the process of macrophage activation. It would also provide another means for more precise evaluation of residual disease in bone marrow of patients treated for hairy cell leukemia.

Thermal Deformation of Very Slender Triangular Rollable and Collapsible Booms

NASA Technical Reports Server (NTRS)

Stohlman, Olive R.; Loper, Erik R.

2016-01-01

Metallic triangular rollable and collapsible (TRAC) booms have deployed two Cubesat-based solar sails in low Earth orbit, making TRAC booms the most popular solar sail deployment method in practice. This paper presents some concerns and solutions surrounding the behavior of these booms in the space thermal environment. A 3.5-cm-tall, 4-meter-long TRAC boom of Elgiloy cobalt alloy, when exposed to direct sunlight in a 1 AU deep space environment, has a predicted tip motion of as much as 0.5 meters. Such large thermal deflections could generate unacceptable distortions in the shape of a supported solar sail, making attitude control of the solar sail spacecraft difficult or impossible. As a possible means of mitigating this issue, the thermal distortion behaviors of three alternative material TRAC booms are investigated and compared with the uncoated Elgiloy baseline boom. A tenfold decrease in induced curvature is shown to be possible relative to the baseline boom. Potential thermal distortions of the LightSail-A solar sail TRAC booms are also examined and compared, although inconclusively, with available on-orbit camera imagery.

GPS-based microenvironment tracker (MicroTrac) model to estimate time–location of individuals for air pollution exposure assessments: Model evaluation in central North Carolina

PubMed Central

Breen, Michael S.; Long, Thomas C.; Schultz, Bradley D.; Crooks, James; Breen, Miyuki; Langstaff, John E.; Isaacs, Kristin K.; Tan, Yu-Mei; Williams, Ronald W.; Cao, Ye; Geller, Andrew M.; Devlin, Robert B.; Batterman, Stuart A.; Buckley, Timothy J.

2014-01-01

A critical aspect of air pollution exposure assessment is the estimation of the time spent by individuals in various microenvironments (ME). Accounting for the time spent in different ME with different pollutant concentrations can reduce exposure misclassifications, while failure to do so can add uncertainty and bias to risk estimates. In this study, a classification model, called MicroTrac, was developed to estimate time of day and duration spent in eight ME (indoors and outdoors at home, work, school; inside vehicles; other locations) from global positioning system (GPS) data and geocoded building boundaries. Based on a panel study, MicroTrac estimates were compared with 24-h diary data from nine participants, with corresponding GPS data and building boundaries of home, school, and work. MicroTrac correctly classified the ME for 99.5% of the daily time spent by the participants. The capability of MicroTrac could help to reduce the time–location uncertainty in air pollution exposure models and exposure metrics for individuals in health studies. PMID:24619294

SU-E-J-48: Imaging Origin-Radiation Isocenter Coincidence for Linac-Based SRS with Novalis Tx

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geraghty, C; Workie, D; Hasson, B

Purpose To implement and evaluate an image-based Winston-Lutz (WL) test to measure the displacement between ExacTrac imaging origin and radiation isocenter on a Novalis Tx system using RIT V6.2 software analysis tools. Displacement between imaging and radiation isocenters was tracked over time. The method was applied for cone-based and MLC-based WL tests. Methods The Brainlab Winston-Lutz phantom was aligned to room lasers. The ExacTrac imaging system was then used to detect the Winston- Lutz phantom and obtain the displacement between the center of the phantom and the imaging origin. EPID images of the phantom were obtained at various gantry andmore » couch angles and analyzed with RIT calculating the phantom center to radiation isocenter displacement. The RIT and Exactrac displacements were combined to calculate the displacement between imaging origin and radiation isocenter. Results were tracked over time. Results Mean displacements between ExacTrac origin and radiation isocenter were: VRT: −0.1mm ± 0.3mm, LNG: 0.5mm ± 0.2mm, LAT: 0.2mm ± 0.2mm (vector magnitude of 0.7 ± 0.2mm). Radiation isocenter was characterized by the mean of the standard deviations of the WL phantom displacements: σVRT: 0.2mm, σLNG: 0.4mm, σLAT: 0.6mm. The linac couch base was serviced to reduce couch walkout. This reduced σLAT to 0.2mm. These measurements established a new baseline of radiation isocenter-imaging origin coincidence. Conclusion The image-based WL test has ensured submillimeter localization accuracy using the ExacTrac imaging system. Standard deviations of ExacTrac-radiation isocenter displacements indicate that average agreement within 0.3mm is possible in each axis. This WL test is a departure from the tradiational WL in that imaging origin/radiation isocenter agreement is the end goal not lasers/radiation isocenter.« less

Trace Assessment for BWR ATWS Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheng, L.Y.; Diamond, D.; Arantxa Cuadra, Gilad Raitses, Arnold Aronson

2010-04-22

A TRACE/PARCS input model has been developed in order to be able to analyze anticipated transients without scram (ATWS) in a boiling water reactor. The model is based on one developed previously for the Browns Ferry reactor for doing loss-of-coolant accident analysis. This model was updated by adding the control systems needed for ATWS and a core model using PARCS. The control systems were based on models previously developed for the TRAC-B code. The PARCS model is based on information (e.g., exposure and moderator density (void) history distributions) obtained from General Electric Hitachi and cross sections for GE14 fuel obtainedmore » from an independent source. The model is able to calculate an ATWS, initiated by the closure of main steam isolation valves, with recirculation pump trip, water level control, injection of borated water from the standby liquid control system and actuation of the automatic depres-surization system. The model is not considered complete and recommendations are made on how it should be improved.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyack, B.E.; Steiner, J.L.; Harmony, S.C.

The PIUS Advanced Reactor is a 640-MW(e) pressurized-water reactor developed by Asea Brown Boveri. A unique feature of the PIUS concept is the absence of mechanical control and shutdown rods. Reactivity normally is controlled by the boron concentration in the coolant and the temperature of the moderator coolant. Analyses of five initiating events have been completed on the basis of calculations performed with the system neutronic and thermal-hydraulic analysis code TRAC-PF1/MOD2. The initiating events analyzed are (1) reactor scram, (2) loss of off-site power (3) main steam-line break, (4) small-break loss of coolant, and (5) large-break loss of coolant. Inmore » addition to the baseline calculation for each sequence, sensitivity studies were performed to explore the response of the PIUS reactor to severe off-normal conditions having a very low probability of occurrence. The sensitivity studies provide insights into the robustness of the design.« less

FAST-TRAC evaluation : evaluation summary report

DOT National Transportation Integrated Search

FAST-TRAC is an Intelligent Transportation System (ITS) that integrates advanced traffic control with a variety of advanced traffic information systems through centralized collection, processing, and dissemination of traffic data. The Road Commission...

SU-E-CAMPUS-J-05: Quantitative Investigation of Random and Systematic Uncertainties From Hardware and Software Components in the Frameless 6DBrainLAB ExacTrac System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keeling, V; Jin, H; Hossain, S

2014-06-15

Purpose: To evaluate setup accuracy and quantify individual systematic and random errors for the various hardware and software components of the frameless 6D-BrainLAB ExacTrac system. Methods: 35 patients with cranial lesions, some with multiple isocenters (50 total lesions treated in 1, 3, 5 fractions), were investigated. All patients were simulated with a rigid head-and-neck mask and the BrainLAB localizer. CT images were transferred to the IPLAN treatment planning system where optimized plans were generated using stereotactic reference frame based on the localizer. The patients were setup initially with infrared (IR) positioning ExacTrac system. Stereoscopic X-ray images (XC: X-ray Correction) weremore » registered to their corresponding digitally-reconstructed-radiographs, based on bony anatomy matching, to calculate 6D-translational and rotational (Lateral, Longitudinal, Vertical, Pitch, Roll, Yaw) shifts. XC combines systematic errors of the mask, localizer, image registration, frame, and IR. If shifts were below tolerance (0.7 mm translational and 1 degree rotational), treatment was initiated; otherwise corrections were applied and additional X-rays were acquired to verify patient position (XV: X-ray Verification). Statistical analysis was used to extract systematic and random errors of the different components of the 6D-ExacTrac system and evaluate the cumulative setup accuracy. Results: Mask systematic errors (translational; rotational) were the largest and varied from one patient to another in the range (−15 to 4mm; −2.5 to 2.5degree) obtained from mean of XC for each patient. Setup uncertainty in IR positioning (0.97,2.47,1.62mm;0.65,0.84,0.96degree) was extracted from standard-deviation of XC. Combined systematic errors of the frame and localizer (0.32,−0.42,−1.21mm; −0.27,0.34,0.26degree) was extracted from mean of means of XC distributions. Final patient setup uncertainty was obtained from the standard deviations of XV (0.57,0.77,0.67mm,0.39,0.35,0.30degree). Conclusion: Statistical analysis was used to calculate cumulative and individual systematic errors from the different hardware and software components of the 6D-ExacTrac-system. Patients were treated with cumulative errors (<1mm,<1degree) with XV image guidance.« less

Evaluations of the setup discrepancy between BrainLAB 6D ExacTrac and cone-beam computed tomography used with the imaging guidance system Novalis-Tx for intracranial stereotactic radiosurgery.

PubMed

Oh, Se An; Park, Jae Won; Yea, Ji Woon; Kim, Sung Kyu

2017-01-01

The objective of this study was to evaluate the setup discrepancy between BrainLAB 6 degree-of-freedom (6D) ExacTrac and cone-beam computed tomography (CBCT) used with the imaging guidance system Novalis Tx for intracranial stereotactic radiosurgery. We included 107 consecutive patients for whom white stereotactic head frame masks (R408; Clarity Medical Products, Newark, OH) were used to fix the head during intracranial stereotactic radiosurgery, between August 2012 and July 2016. The patients were immobilized in the same state for both the verification image using 6D ExacTrac and online 3D CBCT. In addition, after radiation treatment, registration between the computed tomography simulation images and the CBCT images was performed with offline 6D fusion in an offline review. The root-mean-square of the difference in the translational dimensions between the ExacTrac system and CBCT was <1.01 mm for online matching and <1.10 mm for offline matching. Furthermore, the root-mean-square of the difference in the rotational dimensions between the ExacTrac system and the CBCT were <0.82° for online matching and <0.95° for offline matching. It was concluded that while the discrepancies in residual setup errors between the ExacTrac 6D X-ray and the CBCT were minor, they should not be ignored.

Microenvironment Tracker (MicroTrac) Model helps track air quality

EPA Pesticide Factsheets

MicroTrac is a model that uses global positioning system (GPS) data to estimate time of day and duration that people spend in different microenvironments (e.g., indoors and outdoors at home, work, school).

Microenvironment Tracker (MicroTrac) Factsheet

EPA Pesticide Factsheets

MicroTrac is a model developed by EPA that uses GPS data to estimate time of day and duration that people spend in different microenvironments, such as indoors and outdoors at home, work, school, and inside vehicles.

TRAC PAC : the next generation

DOT National Transportation Integrated Search

1999-05-01

The Transportation and Civil Engineering (TRAC) PAC is a toolkit of instructional aids originally built in 1994 to attract middle and high school students to the transportation field. Since that time, users have noted difficulties arising from the PA...

Calculation of design load for the MOD-5A 7.3 mW wind turbine system

NASA Technical Reports Server (NTRS)

Mirandy, L.; Strain, J. C.

1995-01-01

Design loads are presented for the General Electric MOD-SA wind turbine. The MOD-SA system consists of a 400 ft. diameter, upwind, two-bladed, teetered rotor connected to a 7.3 mW variable-speed generator. Fatigue loads are specified in the form of histograms for the 30 year life of the machine, while limit (or maximum) loads have been derived from transient dynamic analysis at critical operating conditions. Loads prediction was accomplished using state of the art aeroelastic analyses developed at General Electric. Features of the primary predictive tool - the Transient Rotor Analysis Code (TRAC) are described in the paper. Key to the load predictions are the following wind models: (1) yearly mean wind distribution; (2) mean wind variations during operation; (3) number of start/shutdown cycles; (4) spatially large gusts; and (5) spatially small gusts (local turbulence). The methods used to develop statistical distributions from load calculations represent an extension of procedures used in past wind programs and are believed to be a significant contribution to Wind Turbine Generator analysis. Test/theory correlations are presented to demonstrate code load predictive capability and to support the wind models used in the analysis. In addition MOD-5A loads are compared with those of existing machines. The MOD-5A design was performed by the General Electric Company, Advanced Energy Program Department, under Contract DEN3-153 with NASA Lewis Research Center and sponsored by the Department of Energy.

78 FR 22034 - Proposed Collection; Comment Request for Notice 2001-1

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-12

... Notice 2001-1, Employer-designed Tip Reporting Program for the Food and Beverage Industry (EmTRAC). DATES... Program for the Food and Beverage Industry (EmTRAC). OMB Number: 1545-1716. Notice Number: Notice 2001-1...

IVHS Institutional and Legal Issues Program: Review of the FAST-TRAC Operational Test

DOT National Transportation Integrated Search

1994-06-01

The FAST-TRAC (Faster and Safer Travel through Traffic Routing and Advanced Controls) operational test attempted to integrate advanced traveler information systems (ATIS) and advanced traffic management system (ATMS) technologies in Oakland County, M...

SU-F-J-42: Comparison of Varian TrueBeam Cone-Beam CT and BrainLab ExacTrac X-Ray for Cranial Radiotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, J; Shi, W; Andrews, D

2016-06-15

Purpose: To compare online image registrations of TrueBeam cone-beam CT (CBCT) and BrainLab ExacTrac x-ray imaging systems for cranial radiotherapy. Method: Phantom and patient studies were performed on a Varian TrueBeam STx linear accelerator (Version 2.5), which is integrated with a BrainLab ExacTrac imaging system (Version 6.1.1). The phantom study was based on a Rando head phantom, which was designed to evaluate isocenter-location dependence of the image registrations. Ten isocenters were selected at various locations in the phantom, which represented clinical treatment sites. CBCT and ExacTrac x-ray images were taken when the phantom was located at each isocenter. The patientmore » study included thirteen patients. CBCT and ExacTrac x-ray images were taken at each patient’s treatment position. Six-dimensional image registrations were performed on CBCT and ExacTrac, and residual errors calculated from CBCT and ExacTrac were compared. Results: In the phantom study, the average residual-error differences between CBCT and ExacTrac image registrations were: 0.16±0.10 mm, 0.35±0.20 mm, and 0.21±0.15 mm, in the vertical, longitudinal, and lateral directions, respectively. The average residual-error differences in the rotation, roll, and pitch were: 0.36±0.11 degree, 0.14±0.10 degree, and 0.12±0.10 degree, respectively. In the patient study, the average residual-error differences in the vertical, longitudinal, and lateral directions were: 0.13±0.13 mm, 0.37±0.21 mm, 0.22±0.17 mm, respectively. The average residual-error differences in the rotation, roll, and pitch were: 0.30±0.10 degree, 0.18±0.11 degree, and 0.22±0.13 degree, respectively. Larger residual-error differences (up to 0.79 mm) were observed in the longitudinal direction in the phantom and patient studies where isocenters were located in or close to frontal lobes, i.e., located superficially. Conclusion: Overall, the average residual-error differences were within 0.4 mm in the translational directions and were within 0.4 degree in the rotational directions.« less

A New App for At-Home Cognitive Training: Description and Pilot Testing on Patients with Multiple Sclerosis.

PubMed

Tacchino, Andrea; Pedullà, Ludovico; Bonzano, Laura; Vassallo, Claudio; Battaglia, Mario Alberto; Mancardi, Gianluigi; Bove, Marco; Brichetto, Giampaolo

2015-08-31

Cognitive impairment is common in people with neurological diseases and severely affects their social and professional life. It has been shown that intensive and personalized cognitive rehabilitation (CR), based on working memory exercises, leads to improved cognitive status of healthy and cognitive-impaired subjects. New technologies would help to promote accessible, at-home, and self-managed CR interventions. The aim of this paper is to describe the design of Cognitive Training Kit (COGNI-TRAcK), an app for mobile devices, to self-administer an at-home, intensive, and personalized CR intervention based on working memory exercises, and test its disposability-to-use (usability, motivation to use, compliance to treatment) on cognitive-impaired patients with multiple sclerosis (MS). COGNI-TRAcK includes user-friendly interfaces for personal data input and management and for CR intervention configurations. Inner routines automatically implement adaptive working load algorithms and allow data processing and analysis. A dedicated team developed COGNI-TRAcK with C# programming language, by using the platform Xamarin Studio 4.0.10 for Android (API level 15 and following). Three exercises based on working memory are now available. To assess the disposability-to-use of the system, patients with MS were selected as likely users due to the young age of disease onset. Cognitive-impaired patients with MS (N=16) with a mean age of 49.06 years (SD 9.10) and a mean score of 3.75 (SD 1.92) on the Expanded Disability Status Scale (EDSS) were submitted to an 8-week at-home intervention administered by the app. The intervention consisted of 5 daily scheduled 30-minute sessions per week. Disposability-to-use of COGNI-TRAcK was investigated by means of a questionnaire administered to patients at the end of the training. The adherence to the treatment was 84% (33.4/40). Of the patients with MS, 94% (15/16) understood the instructions given, 100% (16/16) felt independent to use COGNI-TRAcK at home, 75% (12/16) found the exercises interesting, and 81% (13/16) found the exercises useful and were motivated to use the app again. Moreover, during the exercises, patients with MS were highly motivated to perform well (mean score 3.19/4, SE 0.16), experienced rather low levels of stress (mean score 2.19/4, SE 0.26), were not bored (mean score 1.81/4, SE 0.30), and felt amusement (mean score 2.25/4, SE 0.23). As COGNI-TRAcK is highly usable, motivating, and well-accepted by patients with MS, its effectiveness can now be investigated. To improve COGNI-TRAcK, new releases should contain more working memory exercises, have enhanced perceived amusement, and promote Internet communication procedures for data transfer and fostering remote control of the intervention.

A New App for At-Home Cognitive Training: Description and Pilot Testing on Patients with Multiple Sclerosis

PubMed Central

Bonzano, Laura; Vassallo, Claudio; Battaglia, Mario Alberto; Mancardi, Gianluigi; Bove, Marco

2015-01-01

Background Cognitive impairment is common in people with neurological diseases and severely affects their social and professional life. It has been shown that intensive and personalized cognitive rehabilitation (CR), based on working memory exercises, leads to improved cognitive status of healthy and cognitive-impaired subjects. New technologies would help to promote accessible, at-home, and self-managed CR interventions. Objective The aim of this paper is to describe the design of Cognitive Training Kit (COGNI-TRAcK), an app for mobile devices, to self-administer an at-home, intensive, and personalized CR intervention based on working memory exercises, and test its disposability-to-use (usability, motivation to use, compliance to treatment) on cognitive-impaired patients with multiple sclerosis (MS). Methods COGNI-TRAcK includes user-friendly interfaces for personal data input and management and for CR intervention configurations. Inner routines automatically implement adaptive working load algorithms and allow data processing and analysis. A dedicated team developed COGNI-TRAcK with C# programming language, by using the platform Xamarin Studio 4.0.10 for Android (API level 15 and following). Three exercises based on working memory are now available. To assess the disposability-to-use of the system, patients with MS were selected as likely users due to the young age of disease onset. Cognitive-impaired patients with MS (N=16) with a mean age of 49.06 years (SD 9.10) and a mean score of 3.75 (SD 1.92) on the Expanded Disability Status Scale (EDSS) were submitted to an 8-week at-home intervention administered by the app. The intervention consisted of 5 daily scheduled 30-minute sessions per week. Disposability-to-use of COGNI-TRAcK was investigated by means of a questionnaire administered to patients at the end of the training. Results The adherence to the treatment was 84% (33.4/40). Of the patients with MS, 94% (15/16) understood the instructions given, 100% (16/16) felt independent to use COGNI-TRAcK at home, 75% (12/16) found the exercises interesting, and 81% (13/16) found the exercises useful and were motivated to use the app again. Moreover, during the exercises, patients with MS were highly motivated to perform well (mean score 3.19/4, SE 0.16), experienced rather low levels of stress (mean score 2.19/4, SE 0.26), were not bored (mean score 1.81/4, SE 0.30), and felt amusement (mean score 2.25/4, SE 0.23). Conclusions As COGNI-TRAcK is highly usable, motivating, and well-accepted by patients with MS, its effectiveness can now be investigated. To improve COGNI-TRAcK, new releases should contain more working memory exercises, have enhanced perceived amusement, and promote Internet communication procedures for data transfer and fostering remote control of the intervention. PMID:26323749

A model of systems integration to facilitate ITS deployment : FAST-TRAC phase IV deliverable

DOT National Transportation Integrated Search

2003-04-01

The FAST-TRAC (Faster and Safer Travel through Traffic Routing and Advanced Controls) Intelligent Transportation Systems (ITS) Field Test in Oakland County, an urbanized county in metropolitan Detroit, represents a large and successful systems integr...

Hazardous chemical tracking system (HAZ-TRAC)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bramlette, J D; Ewart, S M; Jones, C E

Westinghouse Idaho Nuclear Company, Inc. (WINCO) developed and implemented a computerized hazardous chemical tracking system, referred to as Haz-Trac, for use at the Idaho Chemical Processing Plant (ICPP). Haz-Trac is designed to provide a means to improve the accuracy and reliability of chemical information, which enhances the overall quality and safety of ICPP operations. The system tracks all chemicals and chemical components from the time they enter the ICPP until the chemical changes form, is used, or becomes a waste. The system runs on a Hewlett-Packard (HP) 3000 Series 70 computer. The system is written in COBOL and uses VIEW/3000,more » TurboIMAGE/DBMS 3000, OMNIDEX, and SPEEDWARE. The HP 3000 may be accessed throughout the ICPP, and from remote locations, using data communication lines. Haz-Trac went into production in October, 1989. Currently, over 1910 chemicals and chemical components are tracked on the system. More than 2500 personnel hours were saved during the first six months of operation. Cost savings have been realized by reducing the time needed to collect and compile reporting information, identifying and disposing of unneeded chemicals, and eliminating duplicate inventories. Haz-Trac maintains information required by the Superfund Amendment Reauthorization Act (SARA), the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) and the Occupational Safety and Health Administration (OSHA).« less

System integration case study : FAST-TRAC : preliminary IV deliverable : #2-systems integration case study

DOT National Transportation Integrated Search

1999-02-12

This report focuses on the system integration aspect of the Transportation Information Management System (TIMS), a component of the FAST-TRAC project. The TIMS functions as the center of a communications network which integrates advanced traffic cont...

78 FR 37877 - Request for Transit Rail Advisory Committee for Safety (TRACS) Nominations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-24

... transportation as FTA implements new statutory authority for public transportation safety oversight. FOR FURTHER... public transportation. Therefore, TRACS membership will be reconfigured to reflect a broader range of... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Request for Transit Rail Advisory...

TRAC performance estimates

NASA Technical Reports Server (NTRS)

Everett, L.

1992-01-01

This report documents the performance characteristics of a Targeting Reflective Alignment Concept (TRAC) sensor. The performance will be documented for both short and long ranges. For long ranges, the sensor is used without the flat mirror attached to the target. To better understand the capabilities of the TRAC based sensors, an engineering model is required. The model can be used to better design the system for a particular application. This is necessary because there are many interrelated design variables in application. These include lense parameters, camera, and target configuration. The report presents first an analytical development of the performance, and second an experimental verification of the equations. In the analytical presentation it is assumed that the best vision resolution is a single pixel element. The experimental results suggest however that the resolution is better than 1 pixel. Hence the analytical results should be considered worst case conditions. The report also discusses advantages and limitations of the TRAC sensor in light of the performance estimates. Finally the report discusses potential improvements.

FloCon 2011 Proceedings

DTIC Science & Technology

2011-01-01

and G. Armitage. Dening and evaluating greynets (sparse darknets ). In LCN󈧉: Proceedings of the IEEE Conference on Local Computer Networks 30th...analysis of distributed darknet trac. In IMC󈧉: Proceedings of the USENIX/ACM Internet Measurement Conference, 2005. Indexing Full Packet Capture Data

Evaluation of user perceptions and behaviors of Fast-Trac : pilot study results

DOT National Transportation Integrated Search

1996-01-01

The purpose of the User Perceptions and Behaviors evaluation component of FAST-TRAC is to understand how users perceive and value the in-vehicle navigation system, ALI-SCOUT, and to determine how the system is used in the Oakland County study area. S...

A mobile trauma database with charge capture.

PubMed

Moulton, Steve; Myung, Dan; Chary, Aron; Chen, Joshua; Agarwal, Suresh; Emhoff, Tim; Burke, Peter; Hirsch, Erwin

2005-11-01

Charge capture plays an important role in every surgical practice. We have developed and merged a custom mobile database (DB) system with our trauma registry (TRACS), to better understand our billing methods, revenue generators, and areas for improved revenue capture. The mobile database runs on handheld devices using the Windows Compact Edition platform. The front end was written in C# and the back end is SQL. The mobile database operates as a thick client; it includes active and inactive patient lists, billing screens, hot pick lists, and Current Procedural Terminology and International Classification of Diseases, Ninth Revision code sets. Microsoft Information Internet Server provides secure data transaction services between the back ends stored on each device. Traditional, hand written billing information for three of five adult trauma surgeons was averaged over a 5-month period. Electronic billing information was then collected over a 3-month period using handheld devices and the subject software application. One surgeon used the software for all 3 months, and two surgeons used it for the latter 2 months of the electronic data collection period. This electronic billing information was combined with TRACS data to determine the clinical characteristics of the trauma patients who were and were not captured using the mobile database. Total charges increased by 135%, 148%, and 228% for each of the three trauma surgeons who used the mobile DB application. The majority of additional charges were for evaluation and management services. Patients who were captured and billed at the point of care using the mobile DB had higher Injury Severity Scores, were more likely to undergo an operative procedure, and had longer lengths of stay compared with those who were not captured. Total charges more than doubled using a mobile database to bill at the point of care. A subsequent comparison of TRACS data with billing information revealed a large amount of uncaptured patient revenue. Greater familiarity and broader use of mobile database technology holds the potential for even greater revenue capture.

GPS-based Microenvironment Tracker (MicroTrac) Model to ...

EPA Pesticide Factsheets

A critical aspect of air pollution exposure assessment is the estimation of the time spent by individuals in various microenvironments (ME). Accounting for the time spent in different ME with different pollutant concentrations can reduce exposure misclassifications, while failure to do so can add uncertainty and bias to risk estimates. In this study, a classification model, called MicroTrac, was developed to estimate time of day and duration spent in eight ME (indoors and outdoors at home, work, school; inside vehicles; other locations) from global positioning system (GPS) data and geocoded building boundaries. Based on a panel study, MicroTrac estimates were compared to 24 h diary data from 7 participants on workdays and 2 participants on nonworkdays, with corresponding GPS data and building boundaries of home, school, and work. MicroTrac correctly classified the ME for 99.5% of the daily time spent by the participants. The capability of MicroTrac could help to reduce the time-location uncertainty in air pollution exposure models and exposure metrics for individuals in health studies. The National Exposure Research Laboratory’s (NERL’s) Human Exposure and Atmospheric Sciences Division (HEASD) conducts research in support of EPA’s mission to protect human health and the environment. HEASD’s research program supports Goal 1 (Clean Air) and Goal 4 (Healthy People) of EPA’s strategic plan. More specifically, our division conducts research to characterize

TRAC, a collaborative computer tool for tracer-test interpretation

NASA Astrophysics Data System (ADS)

Gutierrez, A.; Klinka, T.; Thiéry, D.; Buscarlet, E.; Binet, S.; Jozja, N.; Défarge, C.; Leclerc, B.; Fécamp, C.; Ahumada, Y.; Elsass, J.

2013-05-01

Artificial tracer tests are widely used by consulting engineers for demonstrating water circulation, proving the existence of leakage, or estimating groundwater velocity. However, the interpretation of such tests is often very basic, with the result that decision makers and professionals commonly face unreliable results through hasty and empirical interpretation. There is thus an increasing need for a reliable interpretation tool, compatible with the latest operating systems and available in several languages. BRGM, the French Geological Survey, has developed a project together with hydrogeologists from various other organizations to build software assembling several analytical solutions in order to comply with various field contexts. This computer program, called TRAC, is very light and simple, allowing the user to add his own analytical solution if the formula is not yet included. It aims at collaborative improvement by sharing the tool and the solutions. TRAC can be used for interpreting data recovered from a tracer test as well as for simulating the transport of a tracer in the saturated zone (for the time being). Calibration of a site operation is based on considering the hydrodynamic and hydrodispersive features of groundwater flow as well as the amount, nature and injection mode of the artificial tracer. The software is available in French, English and Spanish, and the latest version can be downloaded from the web site http://trac.brgm.fr">http://trac.brgm.fr.

Identifying autism early: The Toddlers at Risk of Autism Clinic model.

PubMed

Davis, Tessa; Clifton, Deirdre; Papadopoulos, Con

2015-07-01

This paper describes the Toddlers at Risk of Autism Clinic (TRAC), which utilises the Social Attention and Communication Study (SACS) and/or Autism Detection in Early Childhood (ADEC) play-based assessments to facilitate the early diagnosis of autism. A retrospective audit was conducted of all 42 children assessed over a 3-year period in the TRAC. A semi-structured interview and play-based assessment (SACS and ADEC) were used to aid experienced clinicians in diagnosing autism. Intervention was recommended, and families were routinely followed up. Analysis was conducted on the tools used, the outcomes of assessment, diagnosis and stability of diagnosis on follow-up. During this period, 35 boys and 7 girls were assessed, with a mean age of 25 months. The average waiting time for clinic was 11.6 weeks. Twenty-five patients were diagnosed with autism; 90.5% of toddlers given an initial diagnosis retained that diagnosis at follow-up. Out of the 17 children who were not diagnosed with autism in the TRAC, one child was later diagnosed with autism. Experienced clinicians can use the SACS and/or ADEC to assist with a Diagnostic and Statistical Manual diagnosis of autism in toddlers. © 2015 The Authors. Journal of Paediatrics and Child Health © 2015 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

Analysis of corridor delay under SCATS control : FAST-TRAC Phase III deliverable

DOT National Transportation Integrated Search

1998-04-01

The study was designed to determine the change in travel time following the implementation of the Sydney Coordinated Adaptive Traffic System (SCATS) in Oakland County, Michigan. A before/after comparison was used to examine the change in travel time ...

75 FR 51523 - Notice of Meeting of the Transit Rail Advisory Committee for Safety (TRACS)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-20

... Administration (FTA) on matters pertaining to the safety of public transportation systems. TRACS is composed of... Administration Eric Cheng, Utah Department of Transportation Richard W. Clark, California Public Utilities... Grizard, American Public Transportation Association Leonard Hardy, Bay Area Transit Authority Henry...

76 FR 16854 - Notice of Meeting of the Transit Rail Advisory Committee for Safety (TRACS)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-25

... Secretary and the Federal Transit Administrator on matters relating to the safety of public transportation... to the safety of public transportation systems. TRACS is composed of 21 members representing a broad... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Notice of Meeting of the Transit Rail...

Validation of the 16-Gene Recurrence Score in patients with locoregional, high-risk renal cell carcinoma from a phase 3 trial of adjuvant sunitinib.

PubMed

Rini, Brian I; Escudier, Bernard; Martini, Jean-Francois; Magheli, Ahmed; Svedman, Christer; Lopatin, Margarita; Knezevic, Dejan; Goddard, Audrey D; Febbo, Phillip G; Li, Rachel; Lin, Xun; Valota, Olga; Staehler, Michael; Motzer, Robert J; Ravaud, Alain

2018-05-17

Adjuvant sunitinib prolonged disease-free survival (DFS) (hazard ratio [HR] 0.76) in patients with locoregional high-risk renal cell carcinoma (RCC) in the S-TRAC trial (ClinicalTrials.gov NCT00375674). The 16-gene Recurrence Score (RS) assay was previously developed and validated to estimate risk for disease recurrence in patients with RCC post-nephrectomy. This analysis further validated the prognostic value of RS assay in patients from S-TRAC and explored association of RS results with prediction of sunitinib benefit. The analysis was prospectively designed with prespecified genes, algorithm, endpoints, and analytical methods. Primary RCC was available from 212 patients with informed consent; primary analysis focused on patients with T3 RCC. Gene expression was quantitated by RT-PCR. Time to recurrence (TTR), DFS, and renal cancer-specific survival (RCSS) were analyzed using Cox proportional hazards regression. Results: Baseline characteristics were similar between patients with and without RS results, and between the sunitinib and placebo arms among patients with RS results. RS results predicted TTR, DFS, and RCSS in both arms, with the strongest results observed in the placebo arm. When high versus low RS groups were compared, HR for recurrence was 9.18 (95% CI, 2.15-39.24; P < 0.001) in the placebo arm; interaction of RS results with treatment was not significant. Conclusions: The strong prognostic performance of the 16-gene RS assay was confirmed in S-TRAC, and the RS assay is now supported by level IB evidence. RS results may help identify patients at high risk for recurrence who may derive higher absolute benefit from adjuvant therapy. Copyright ©2018, American Association for Cancer Research.

A Comparison of Measured and Predicted XV-15 Tiltrotor Surface Acoustic Pressures

NASA Technical Reports Server (NTRS)

Lyle, Karen H.; Burley, Casey L.; Prichard, Devon S.

1997-01-01

Predicted XV-15 exterior surface acoustic pressures are compared with previously published experimental data. Surface acoustic pressure transducers were concentrated near the tip-path-plane of the rotor in airplane mode. The comparison emphasized cruise conditions which are of interest for tiltrotor interior noise - level flight for speeds ranging from 72 m/s to 113 m/s. The predictions were produced by components of the NASA Langley Tiltrotor Aeroacoustic Code (TRAC) system of computer codes. Comparisons between measurements and predictions were made in both the time and frequency domains, as well as overall sound pressure levels. In general, the predictions replicated the measured data well. Discrepancies between measurements and predictions were noted. Some of the discrepancies were due to poor correlation of the measured data with the rotor tach signal. In other cases limitations of the predictive methodology have been indicated.

Final report on the analyses of traffic accidents : Fast-Trac--phase 3, deliverable. Semi-annual reports on total accidents : trends, types and analysis of before and after studies

DOT National Transportation Integrated Search

1996-12-01

This report contains the results of an analysis of : traffic accidents in the City of Troy, Michigan, where : the Sydney Coordinated Adaptive Traffic System : (SCATS) was deployed as part of a federal demonstration : program. The analyses includes a ...

77 FR 5876 - Notice of Meeting of the Transit Rail Advisory Committee for Safety (TRACS)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-06

... the safety of public transportation systems. TRACS is comprised of 26 members, including 7 new members... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Notice of Meeting of the Transit Rail... meeting. SUMMARY: This notice announces a public meeting of the Transit Rail Advisory Committee for Safety...

78 FR 28285 - Notice of Meeting of the Transit Rail Advisory Committee for Safety (TRACS)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-14

... the safety of public transportation systems. TRACS is composed of 24 members representing a broad base... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Notice of Meeting of the Transit Rail... meeting. SUMMARY: This notice announces a public meeting of the Transit Rail Advisory Committee for Safety...

78 FR 67212 - Notice of Meeting of the Transit Rail Advisory Committee for Safety (TRACS)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-08

... the safety of public transportation systems. DATES: The TRACS meeting will be held on November 21... Letter Report on the Development of the National Public Transportation Safety Plan (4) Review of the Draft Letter Report on Public Transportation Agency Plans (5) Public Comments (6) Wrap Up As previously...

Distance Learning Methodologies. TRANSCOM Regulating and Command & Control Evacuation System (TRAC2ES).

ERIC Educational Resources Information Center

Bloomquist, Carroll R.

The TRANSCOM (Transportation Command) Regulating Command and Control Evacuation System (TRAC2ES), which applies state-of-the-art technology to manage global medical regulating (matching patients to clinical availability) and medical evacuation processes, will be installed at all Department of Defense medical locations globally. A combination of…

Keeping Track Every Step of the Way

NASA Technical Reports Server (NTRS)

2001-01-01

Knowledge Sharing Systems, Inc., a producer of intellectual assets management software systems for the federal government, universities, non-profit laboratories, and private companies, constructed and presently manages the NASA Technology Tracking System, also known as TechTracS. Under contract to Langley Research Center, TechTracS identifies and captures all NASA technologies, manages the patent prosecution process, and then tracks their progress en route to commercialization. The system supports all steps involved in various technology transfer activities, and is considered the premier intellectual asset management system used in the federal government today. NASA TechTracS consists of multiple relational databases and web servers, located at each of the 10 field centers, as well as NASA Headquarters. The system is capable of supporting the following functions: planning commercial technologies; commercialization activities; reporting new technologies and inventions; and processing and tracking intellectual property rights, licensing, partnerships, awards, and success stories. NASA TechTracS is critical to the Agency's ongoing mission to commercialize its revolutionary technologies in a variety of sectors within private industry, both aerospace and non- aerospace.

COMBATXXI: Usage and Analysis at TACOM

DTIC Science & Technology

2011-06-20

Prescribed by ANSI Std Z39-18 Operational Effectiveness UNCLASSIFIED UNCLASSIFIED Outline  Who We Are  Our Equipment  Our Customers  COMBATXXI Model ...Research, Development and Engineering Center Our Customers 5 Operational Effectiveness UNCLASSIFIED UNCLASSIFIED Model Overview  Combined Arms...Analysis Tool for the 21st Century (COMBATXXI) - Developed jointly by TRAC- White Sands Missle Range (WSMR) and Marine Corps Combat Development Command

77 FR 53913 - River Bend Industries, LLC, Including On-Site Leased Workers From FirstStaff, Trac Staffing, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-04

..., LLC, Including On-Site Leased Workers From FirstStaff, Trac Staffing, and Worksource, Inc., Fort Smith... Staffing, Worksource, Inc., Fort Smith, Arkansas. The Department's notice of determination was published in... Worksource, Inc. were employed on-site at the Fort Smith, Arkansas location of River Bend Industries, LLC...

TRAC FY15 Research Planning and Elicitation

DTIC Science & Technology

2014-09-30

Wargaming and Simulation Directorate . . . . . . . . . . . . . C-2 Table C–7. FLVN-Operations Directorate . . . . . . . . . . . . . . . . . . . . . . C...Studies and Analysis III Directorate . . . . . . . . . . . . . . C-4 Table C–14.WSMR - Modeling and Simulation Directorate...Directorate - Mr. Decker • Wargaming and Simulation Directorate - Mr. Johnson • Operations Directorate - Ms. Fratzel • Scenarios and Data Directorate - Mr

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sattarivand, Mike; Summers, Clare; Robar, James

Purpose: To evaluate the validity of using spine as a surrogate for tumor positioning with ExacTrac stereoscopic imaging in lung stereotactic body radiation therapy (SBRT). Methods: Using the Novalis ExacTrac x-ray system, 39 lung SBRT patients (182 treatments) were aligned before treatment with 6 degrees (6D) of freedom couch (3 translations, 3 rotations) based on spine matching on stereoscopic images. The couch was shifted to treatment isocenter and pre-treatment CBCT was performed based on a soft tissue match around tumor volume. The CBCT data were used to measure residual errors following ExacTrac alignment. The thresholds for re-aligning the patients basedmore » on CBCT were 3mm shift or 3° rotation (in any 6D). In order to evaluate the effect of tumor location on residual errors, correlations between tumor distance from spine and individual residual errors were calculated. Results: Residual errors were up to 0.5±2.4mm. Using 3mm/3° thresholds, 80/182 (44%) of the treatments required re-alignment based on CBCT soft tissue matching following ExacTrac spine alignment. Most mismatches were in sup-inf, ant-post, and roll directions which had larger standard deviations. No correlation was found between tumor distance from spine and individual residual errors. Conclusion: ExacTrac stereoscopic imaging offers a quick pre-treatment patient alignment. However, bone matching based on spine is not reliable for aligning lung SBRT patients who require soft tissue image registration from CBCT. Spine can be a poor surrogate for lung SBRT patient alignment even for proximal tumor volumes.« less

Land Warrior (LW)/Mounted Warrior (MW) DOTMLPF Assessment

DTIC Science & Technology

2007-06-01

the DOTMLPF impacts of equipping a Stryker battalion with MW and LW? 3) What is the estimated life cycle cost (LCC) of each LW BOIP alternative? 4...A R E D A T A Assessed costs included: - Support Equipment/Disposal. - Contractor Logistics Support. - Ensemble Hardware...DOTMLPF . 3 - Cost . LUT Navigation Experiment Lethality Experiment AMSAA TRAC-WSMR TRAC-WSMR ATEC LW Test Unit

Wartime critical care air transport.

PubMed

Bridges, Elizabeth; Evers, Karen

2009-04-01

Describe the characteristics/enroute care of casualties transported by USAF Critical Care Air Transport Teams (CCATT) during Operation Enduring Freedom/Iraqi Freedom (OEF/OIF). Retrospective review of TRAC2ES and CCATT Mission Reports (Oct 2001-May 2006). 3492 patient moves (2439 patients). Moves by route: within Area of Responsibility (AOR) (n = 261); AOR-Landstuhl (LRMC) (n = 1995), Germany-CONUS (n = 1188). For AOR-LRMC: BI (64%), NBI (8%), Disease (25%). Among injured (n = 1491), 69% suffered polytrauma, primarily d/t explosions. Injury area: extremities (63%), head (55%), thorax (46%), abdomen (31%), neck (17%). Injury type: soft tissue (64%), orthopedic (45%), thoracic (35%), skull fracture (27%), brain injury (25%). Disease diagnoses: cardiac (15%) and pulmonary (8%). This is the first analysis of OEF/OIF CCATT patients. Phase 1 of this study demonstrates the strengths and limitations of TRAC2ES and CCATT Mission Reports to describe the characteristics/enroute care of this unique population.

Deployed Analyst History Report, Volume 2. Analytic Support to Combat Operations in the Philippines (2011-2014)

DTIC Science & Technology

2015-12-01

Army Training and Doctrine Command (TRADOC) Analysis Center (TRAC) to the Philippines for Operation ENDURING FREEDOM – Philippines (OEF-P). PROJECT...management, doctrine and force development, training management, system testing, system acquisition, decision analysis, and resource management, as...influenced procurement decisions and reshaped Army doctrine . Additionally, CAA itself has benefited in numerous ways. Combat experience provides analysts

Implicit time-integration method for simultaneous solution of a coupled non-linear system

NASA Astrophysics Data System (ADS)

Watson, Justin Kyle

Historically large physical problems have been divided into smaller problems based on the physics involved. This is no different in reactor safety analysis. The problem of analyzing a nuclear reactor for design basis accidents is performed by a handful of computer codes each solving a portion of the problem. The reactor thermal hydraulic response to an event is determined using a system code like TRAC RELAP Advanced Computational Engine (TRACE). The core power response to the same accident scenario is determined using a core physics code like Purdue Advanced Core Simulator (PARCS). Containment response to the reactor depressurization in a Loss Of Coolant Accident (LOCA) type event is calculated by a separate code. Sub-channel analysis is performed with yet another computer code. This is just a sample of the computer codes used to solve the overall problems of nuclear reactor design basis accidents. Traditionally each of these codes operates independently from each other using only the global results from one calculation as boundary conditions to another. Industry's drive to uprate power for reactors has motivated analysts to move from a conservative approach to design basis accident towards a best estimate method. To achieve a best estimate calculation efforts have been aimed at coupling the individual physics models to improve the accuracy of the analysis and reduce margins. The current coupling techniques are sequential in nature. During a calculation time-step data is passed between the two codes. The individual codes solve their portion of the calculation and converge to a solution before the calculation is allowed to proceed to the next time-step. This thesis presents a fully implicit method of simultaneous solving the neutron balance equations, heat conduction equations and the constitutive fluid dynamics equations. It discusses the problems involved in coupling different physics phenomena within multi-physics codes and presents a solution to these problems. The thesis also outlines the basic concepts behind the nodal balance equations, heat transfer equations and the thermal hydraulic equations, which will be coupled to form a fully implicit nonlinear system of equations. The coupling of separate physics models to solve a larger problem and improve accuracy and efficiency of a calculation is not a new idea, however implementing them in an implicit manner and solving the system simultaneously is. Also the application to reactor safety codes is new and has not be done with thermal hydraulics and neutronics codes on realistic applications in the past. The coupling technique described in this thesis is applicable to other similar coupled thermal hydraulic and core physics reactor safety codes. This technique is demonstrated using coupled input decks to show that the system is solved correctly and then verified by using two derivative test problems based on international benchmark problems the OECD/NRC Three mile Island (TMI) Main Steam Line Break (MSLB) problem (representative of pressurized water reactor analysis) and the OECD/NRC Peach Bottom (PB) Turbine Trip (TT) benchmark (representative of boiling water reactor analysis).

An overview of the OmniTRACS: The first operational mobile Ku-band satellite communications

NASA Technical Reports Server (NTRS)

Salmasi, Allen

1988-01-01

The service features of the OmniTRACS system developed by Omninet Communications Services of Los Angeles, California are described. This system is the first operational mobile Ku-band satellite communications system that provides two-way messaging and position determination and reporting services to mobile users on a nationwide basis. The system uses existing Ku-band satellites under a secondary international allocation for mobile satellite services.

Technical characteristics of the OmniTRACS: The first operation mobile Ku-band satellite communications system

NASA Technical Reports Server (NTRS)

Antonio, Franklin P.; Gilhousen, Klein S.; Jacobs, Irwin M.; Weaver, Linday A., Jr.

1988-01-01

The techinical characteristics of the OmniTRACS system are described. The system is the first operational mobile Ku-band satellite communications system and provides two-way message and position determination service to mobile terminals using existing Ku-band satellites. Interference to and from the system is minimized by the use of special spread-spectrum techniques, together with low power and low data rate transmissions.

How the Theory of Computing Can Help in Space Exploration

NASA Technical Reports Server (NTRS)

Kreinovich, Vladik; Longpre, Luc

1997-01-01

The opening of the NASA Pan American Center for Environmental and Earth Sciences (PACES) at the University of Texas at El Paso made it possible to organize the student Center for Theoretical Research and its Applications in Computer Science (TRACS). In this abstract, we briefly describe the main NASA-related research directions of the TRACS center, and give an overview of the preliminary results of student research.

Quantifying the impact of adaptive traffic control systems on crash frequency and severity: Evidence from Oakland County, Michigan.

PubMed

Fink, Joshua; Kwigizile, Valerian; Oh, Jun-Seok

2016-06-01

Despite seeing widespread usage worldwide, adaptive traffic control systems have experienced relatively little use in the United States. Of the systems used, the Sydney Coordinated Adaptive Traffic System (SCATS) is the most popular in America. Safety benefits of these systems are not as well understood nor as commonly documented. This study investigates the safety benefits of adaptive traffic control systems by using the large SCATS-based system in Oakland County, MI known as FAST-TRAC. This study uses data from FAST-TRAC-controlled intersections in Oakland County and compares a wide variety of geometric, traffic, and crash characteristics to similar intersections in metropolitan areas elsewhere in Michigan. Data from 498 signalized intersections are used to conduct a cross-sectional analysis. Negative binomial models are used to estimate models for three dependent crash variables. Multinomial logit models are used to estimate an injury severity model. A variable tracking the presence of FAST-TRAC controllers at intersections is used in all models to determine if a SCATS-based system has an impact on crash occurrences or crash severity. Estimates show that the presence of SCATS-based controllers at intersections is likely to reduce angle crashes by up to 19.3%. Severity results show a statistically significant increase in non-serious injuries, but not a significant reduction in incapacitating injuries or fatal accidents. Copyright © 2016 Elsevier Ltd and National Safety Council. All rights reserved.

TRAC-BF1 thermal-hydraulic, ANSYS stress analysis for core shroud cracking phenomena

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoop, U.; Feltus, M.A.; Baratta, A.J.

1996-12-31

The U.S. Nuclear Regulatory Commission sent Generic Letter 94-03 informing all licensees about the intergranular stress corrosion cracking (IGSCC) of core shrouds found in both Dresden unit I and Quad Cities unit 1. The letter directed all licensees to perform safety analysis of their boiling water reactor (BWR) units. Two transients of special concern for the core shroud safety analysis include the main steam line break (MSLB) and recirculation line break transient.

MODFLOW 2.0: A program for predicting moderator flow patterns

NASA Astrophysics Data System (ADS)

Peterson, P. F.; Paik, I. K.

1991-07-01

Sudden changes in the temperature of flowing liquids can result in transient buoyancy forces which strongly impact the flow hydrodynamics via flow stratification. These effects have been studied for the case of potential flow of stratified liquids to line sinks, but not for moderator flow in SRS reactors. Standard codes, such as TRAC and COMMIX, do not have the capability to capture the stratification effect, due to strong numerical diffusion which smears away the hot/cold fluid interface. A related problem with standard codes is the inability to track plumes injected into the liquid flow, again due to numerical diffusion. The combined effects of buoyant stratification and plume dispersion have been identified as being important in the operation of the Supplementary Safety System which injects neutron-poison ink into SRS reactors to provide safe shutdown in the event of safety rod failure. The MODFLOW code discussed here provides transient moderator flow pattern information with stratification effects, and tracks the location of ink plumes in the reactor. The code, written in Fortran, is compiled for Macintosh II computers, and includes subroutines for interactive control and graphical output. Removing the graphics capabilities, the code can also be compiled on other computers. With graphics, in addition to the capability to perform safety related computations, MODFLOW also provides an easy tool for becoming familiar with flow distributions in SRS reactors.

Calculation of the temperature in the container unit with a modified design for the production of {sup 99}Mo at the VVR-Ts research reactor facility (IVV.10M)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kazantsev, A. A., E-mail: kazantsevanatoly@gmail.com; Sergeev, V. V.; Kochnov, O. Yu.

The temperature regime is calculated for two different designs of containers with uranium-bearing material for the upgraded VVR-Ts research reactor facility (IVV.10M). The containers are to be used in the production of {sup 99}Mo. It is demonstrated that the modification of the container design leads to a considerable temperature reduction and an increase in the near-wall boiling margin and allows one to raise the amount of material loaded into the container. The calculations were conducted using the international thermohydraulic contour code TRAC intended to analyze the technical safety of water-cooled nuclear power units.

Holloman AFB, New Mexico. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

DTIC Science & Technology

1982-04-12

A RC ..... sl6 3i4 ~ N0 A.o 0 o2 *I A3 05 .7 0 to TRACE A 5S :S TRAC .29 .0.0 *2.. *,.j st16 &TRC T ACt la S4 :01 o Ŕ TRAC risAc *4 ?P.TAC *I .0 .02...2l 046 t.2 145 .14 TRACE TRACI T*A TRI 004....~ 60 A001. sOJa .. , 46 .31 .04 .01 6 at .0 .2 .10 47 1_ 1_ - -A .121 __ 48 1.2 .61 .0 TRAC 2.9 l.9 al...r - sea--vu 6s 23.6 *7.6 20 1 9 26 1.9 7 02__1 wo 10mS 0 .5 02U*1*7 9 w 91 "m,. om .4FVC%. LA ~im wm ul 19 292 Ze* ~ U -A- GLiCBAL CLIMATOLOGY

SU-F-J-24: Setup Uncertainty and Margin of the ExacTrac 6D Image Guide System for Patients with Brain Tumors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, S; Oh, S; Yea, J

Purpose: This study evaluated the setup uncertainties for brain sites when using BrainLAB’s ExacTrac X-ray 6D system for daily pretreatment to determine the optimal planning target volume (PTV) margin. Methods: Between August 2012 and April 2015, 28 patients with brain tumors were treated by daily image-guided radiotherapy using the BrainLAB ExacTrac 6D image guidance system of the Novalis-Tx linear accelerator. DUONTM (Orfit Industries, Wijnegem, Belgium) masks were used to fix the head. The radiotherapy was fractionated into 27–33 treatments. In total, 844 image verifications were performed for 28 patients and used for the analysis. The setup corrections along with themore » systematic and random errors were analyzed for six degrees of freedom in the translational (lateral, longitudinal, and vertical) and rotational (pitch, roll, and yaw) dimensions. Results: Optimal PTV margins were calculated based on van Herk et al.’s [margin recipe = 2.5∑ + 0.7σ − 3 mm] and Stroom et al.’s [margin recipe = 2∑ + 0.7σ] formulas. The systematic errors (∑) were 0.72, 1.57, and 0.97 mm in the lateral, longitudinal, and vertical translational dimensions, respectively, and 0.72°, 0.87°, and 0.83° in the pitch, roll, and yaw rotational dimensions, respectively. The random errors (σ) were 0.31, 0.46, and 0.54 mm in the lateral, longitudinal, and vertical rotational dimensions, respectively, and 0.28°, 0.24°, and 0.31° in the pitch, roll, and yaw rotational dimensions, respectively. According to van Herk et al.’s and Stroom et al.’s recipes, the recommended lateral PTV margins were 0.97 and 1.66 mm, respectively; the longitudinal margins were 1.26 and 3.47 mm, respectively; and the vertical margins were 0.21 and 2.31 mm, respectively. Conclusion: Therefore, daily setup verifications using the BrainLAB ExacTrac 6D image guide system are very useful for evaluating the setup uncertainties and determining the setup margin.∑σ.« less

Preliminary calculations related to the accident at Three Mile Island

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kirchner, W.L.; Stevenson, M.G.

This report discusses preliminary studies of the Three Mile Island Unit 2 (TMI-2) accident based on available methods and data. The work reported includes: (1) a TRAC base case calculation out to 3 hours into the accident sequence; (2) TRAC parametric calculations, these are the same as the base case except for a single hypothetical change in the system conditions, such as assuming the high pressure injection (HPI) system operated as designed rather than as in the accident; (3) fuel rod cladding failure, cladding oxidation due to zirconium metal-steam reactions, hydrogen release due to cladding oxidation, cladding ballooning, cladding embrittlement,more » and subsequent cladding breakup estimates based on TRAC calculated cladding temperatures and system pressures. Some conclusions of this work are: the TRAC base case accident calculation agrees very well with known system conditions to nearly 3 hours into the accident; the parametric calculations indicate that, loss-of-core cooling was most influenced by the throttling of High-Pressure Injection (HPI) flows, given the accident initiating events and the pressurizer electromagnetic-operated valve (EMOV) failing to close as designed; failure of nearly all the rods and gaseous fission product gas release from the failed rods is predicted to have occurred at about 2 hours and 30 minutes; cladding oxidation (zirconium-steam reaction) up to 3 hours resulted in the production of approximately 40 kilograms of hydrogen.« less

Financial Health of the Higher Education Sector: Financial Results and TRAC Outcomes 2014-15. Issues Paper. March 2016/04

ERIC Educational Resources Information Center

Higher Education Funding Council for England, 2016

2016-01-01

This report provides an overview of the current financial health of the Higher Education Funding Council for England (HEFCE) funded higher education sector in England. This does not include directly funded further education or other colleges, or alternative providers of higher education. The analysis covers financial results for the academic year…

SUS Source Level Error Analysis

DTIC Science & Technology

1978-01-20

RIECIP1IEN’ CATALOG NUMBER * ITLE (and SubaltIe) S. TYP aof REPORT & _V9RCO SUS~ SOURCE LEVEL ERROR ANALYSIS & Fia 1.r,. -. pAURWORONTIUMm N (s)$S...Fourier Transform (FFTl) SUS Signal model ___ 10 TRA&C (CeEOINIMII1& ro"* *140O tidat n9#*#*Y a"d 0e~ntiff 6T 69*.4 apbt The report provides an analysis ...of major terms which contribute to signal analysis error in a proposed experiment to c-librate sourr - I levels of SUS (Signal Underwater Sound). A

Data-Base Software For Tracking Technological Developments

NASA Technical Reports Server (NTRS)

Aliberti, James A.; Wright, Simon; Monteith, Steve K.

1996-01-01

Technology Tracking System (TechTracS) computer program developed for use in storing and retrieving information on technology and related patent information developed under auspices of NASA Headquarters and NASA's field centers. Contents of data base include multiple scanned still images and quick-time movies as well as text. TechTracS includes word-processing, report-editing, chart-and-graph-editing, and search-editing subprograms. Extensive keyword searching capabilities enable rapid location of technologies, innovators, and companies. System performs routine functions automatically and serves multiple users.

InfoTrac TFD: a microcomputer implementation of the Transcription Factor Database TFD with a graphical user interface.

PubMed

Hoeck, W G

1994-06-01

InfoTrac TFD provides a graphical user interface (GUI) for viewing and manipulating datasets in the Transcription Factor Database, TFD. The interface was developed in Filemaker Pro 2.0 by Claris Corporation, which provides cross platform compatibility between Apple Macintosh computers running System 7.0 and higher and IBM-compatibles running Microsoft Windows 3.0 and higher. TFD ASCII-tables were formatted to fit data into several custom data tables using Add/Strip, a shareware utility and Filemaker Pro's lookup feature. The lookup feature was also put to use to allow TFD data tables to become linked within a flat-file database management system. The 'Navigator', consisting of several pop-up menus listing transcription factor abbreviations, facilitates the search for transcription factor entries. Data are presented onscreen in several layouts, that can be further customized by the user. InfoTrac TFD makes the transcription factor database accessible to a much wider community of scientists by making it available on two popular microcomputer platforms.

[Control of postoperative hemorrhage in isolated coronary bypass surgery: comparison of tranexamic acid effects in off-pump surgery with aprotinin effects in conventional surgery].

PubMed

Bordalo, Alvaro D B; Nobre, Angelo L; Silva, Fernanda; Serpa, Carlos; Cravino, João

2011-01-01

In spite of the strong criticism elicited thereafter, the results of a multicentric study on the consequences of several perioperative anti-hemorrhagic strategies in cardiac surgery, published five years ago, led to the aprotinin (Aprot) withdrawal from the market and its progressive replacement by tranexamic acid (TrAc) in many surgical departments. To evaluate the hemostatic effects and clinical consequences of TrAc use or non-use in off-pump coronary bypass surgery (CABG) and compare them with those of Aprot use or non-use in conventional (conv) CABG. Retrospective analysis of 2 groups (Gr) of patients (pts): GrA - 252 pts undergoing isolated conv CABG (GrA1 - 185 pts submitted to an intra-operative full-dose Aprot protocol; GrA2 - 67 pts operated without Aprot); GrB - 383 pts undergoing isolated off-pump CABG (GrB1 - 136 pts submitted to an intra-operative low-dose TrAc protocol; GrB2 - 247 pts operated in absence of TrAc). Pre-operative clinical characteristics (GrA1 vs GrA2, GrB1 vs GrB2): mean age (years) - 65 vs 64 (NS), 64 vs 64; female gender - 20% vs 21% (NS), 23% vs 20% (NS); logistic Euroscore - 5.1% vs 6.2% (NS), 6.3% vs 5.5% (NS); chronic renal failure - 21% vs 27% (NS), 27% vs 25% (NS); diffuse coronary artery disease - 34% vs 42% (NS), 36% vs 30% (NS); pre-operative betablocker treatment - 64% vs 55% (NS), 74% vs 71% (NS); statin therapy for > 3 months - 78% vs 82% (NS), 81% vs 85% (NS). Pts have been operated by 4 surgeons largely experienced in both CABG modalities. Antiplatelet therapy was stopped => 4 days prior to surgery (but aspirin was maintained in high-risk pts). Results (GrA1 vs GrA2, GrB1 vs GrB2): 1) Bleeding (mL/pt - mean): 783 vs 1375 (p < 0.001), 1061 vs 1368 (p < 0.001); blood loss > 1500 mL (%pts) - 5.4% vs 34% (p < 0.0001), 12% vs 28% (p < 0.001); surgical re-exploration for bleeding - 1.1% vs 3.0% (NS), 2.2% vs 2.0% (NS). 2) Transfusion of blood products (U/pt - mean): plasma - 0.56 vs 2.19 (p < 0.001), 1.45 vs 1.03 (p < 0.05); platelets - 0.09 vs 0.22 (p < 0.02), 0.24 vs 0.15 (NS). 3) Renal function (%pts): increased serum cre- atinine - 56% vs 56%, 55% vs 38% (p < 0.001); hemofiltration use - 1.1% vs 1.5% (NS), 1.5% vs 0.4% (NS). 4) Perioperative myocardial infarction - 21.6% vs 17.9% (NS), 17.6% vs 14.6% (NS); other ischemic events - 3.2% vs 3.0% (NS), 1.5% vs 1.2% (NS). 5) Hospital mortality: 4.8% vs 4.5% (NS), 4.4% vs 1.6% (NS). 1) TrAc does not reduce the risk of surgical re-exploration for bleeding. 2) Taking into account the differences between conv CABG and off-pump CABG, TrAc hemostatic effect seems to be inferior to that of Aprot, without offering a better safety profile in terms of lesser renal or ischemic risk as a counterpart.

Applying Subject Matter Expertise (SME) Elicitation Techniques to TRAC Studies

DTIC Science & Technology

2014-09-30

prioritisation, budgeting and resource allocation with multi-criteria decision analysis and decision conferencing ”. English. In: Annals of Operations... electronically . Typically, in responding to survey items, experts are not expected to elaborate beyond providing responses in the format requested in the...between them, however irrelevant to probability Kynn and Ayyub.84 For example, an electronic jamming device might disrupt a cell phone signal at certain

The Shock and Vibration Bulletin. Part 1. Keynote Address, Invited Papers, Panel Sessions, Modal Test and Analysis.

DTIC Science & Technology

1978-09-01

SNAPSHOT PICTURE VIDEO TAPE 35-MM PHOTO TRANSPARENCY MICROFILM Figure 2 - Gross Area Information Density other across the organization. Then we developed...the finite element In the modeling of a tor- method. The torpedo hull is divided pedo for shock and vibration analysis, ,. into primary structural...length of the tor- 16. Figure 15 presents the magnitude pedo with several circumferential trac- and phase of motor motion, and Fig. 16 ings at

Multidimensional Mixing Behavior of Steam-Water Flow in a Downcomer Annulus During LBLOCA Reflood Phase with a Direct Vessel Injection Mode

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kwon, Tae-Soon; Yun, Byong-Jo; Euh, Dong-Jin

Multidimensional thermal-hydraulic behavior in the downcomer annulus of a pressurized water reactor (PWR) vessel with a direct vessel injection mode is presented based on the experimental observation in the MIDAS (multidimensional investigation in downcomer annulus simulation) steam-water test facility. From the steady-state test results to simulate the late reflood phase of a large-break loss-of-coolant accident (LBLOCA), isothermal lines show the multidimensional phenomena of a phasic interaction between steam and water in the downcomer annulus very well. MIDAS is a steam-water separate effect test facility, which is 1/4.93 linearly scaled down to a 1400-MW(electric) PWR type of a nuclear reactor, focusedmore » on understanding multidimensional thermal-hydraulic phenomena in a downcomer annulus with various types of safety injection during the refill or reflood phase of an LBLOCA. The initial and the boundary conditions are scaled from the pretest analysis based on the preliminary calculation using the TRAC code. The superheated steam with a superheating degree of 80 K at a given downcomer pressure of 180 kPa is injected equally through three intact cold legs into the downcomer.« less

Sensitivity Analysis of a Cognitive Architecture for the Cultural Geography Model

DTIC Science & Technology

2011-12-01

developmental inquiry. American Psychologist, 34(10), 906–911. Gazzaniga, M. S . (2004) The cognitive neurosciences III. Cambridge: MIT Press. Greeno, J. G...129 ix LIST OF FIGURES Situation-Based Cognitive Architecture (From Alt et al., 2011) .....................13 Figure 1. Theory of Planned...Harold, CG Model developer at TRAC-MTRY, who spend countless hours explaining to me the implementation of the Cognitive Architecture and CG model

Sociocultural Behavior Research and Engineering in the Department of Defense Context

DTIC Science & Technology

2011-09-01

return on investment. Section IV provides a set of principles and practices to ensure that DoD investments are cost effective and have high...projects. The U.S. Army Training and Doctrine Command (TRADOC) Analysis Center (TRAC), the Naval Postgraduate School (NPS), the OSD’s Cost Assessment... cost -effectively allocating resources targeted toward relevant problems. The OSD HSCB Modeling Program is using that approach to rapidly implement a

Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children- a medical center experience.

PubMed

Lin, Chien-Ming; Fan, Hueng-Chuen; Chao, Tsu-Yi; Chu, Der-Ming; Lai, Chi-Chieh; Wang, Chih-Chien; Chen, Shyi-Jou

2016-05-03

Children with longstanding use of antiepileptic drugs (AEDs) are susceptible to developing low bone mineral density and an increased fracture risk. However, the literature regarding the effects of AEDs on growth in epileptic children is limited. The aim of this study was to investigate the potential effects of valproate (VPA) and/or oxcarbazepine (OXC) therapy on growth velocity and bone metabolism. Seventy-three ambulatory children (40 boys and 33 girls) with epilepsy, aged between 1 and 18 years (mean age 9.8 ± 4.1 years), were evaluated for growth velocity before and for 1 year after VPA and/or OXC treatment. The bone resorption marker serum tartrate-resistant acid phosphatase 5b (TRAcP5b) and the bone formation marker serum bone-specific alkaline phosphatase (BAP) were measured post-AEDs therapy for 1 year. The difference in growth velocity (ΔHt) and body weight change (ΔWt) between pre- and post-AEDs treatment were -1.0 ± 2.8 cm/year (P < 0.05) and 0.1 ± 3.9 kg/year (P = 0.84), respectively. The study population had serum TRAcP5b-SDS of -1.6 ± 1.2 and BAP-SDS of 1.7 ± 3.7 compared with sex- and age-matched healthy children. Significant correlation between serum TRAcP 5b and BAP activities was noted (r = 0.60, p < 0.001). There was a positive correlation between growth velocity and serum TRAcP 5b activity after AED treatment (r = 0.42, p < 0.01). No correlation was found between ΔHt, ΔWt, serum TRAcP 5b, BAP activity and types of AEDs. Growth velocity was significantly decreased in epileptic children after 1 year of VPA and/or OXC treatment. The effect of VPA and/or OXC therapy on dysregulation of bone metabolism might play a crucial role in physical growth.

[Frameless set-up with ExacTrac® system for stereotactic radiotherapy of brain metastasis: Descriptive study from five French centres].

PubMed

Ohnleiter, T; Mahé, M-A; Biau, J; Wdowczyk, D; Clavier, J-B; Antoni, D; Noël, G

2016-12-01

This study aimed to analyse the positioning protocols with the ExacTrac ® system, associated with a dedicated linear accelerator such as Novalis ® , for stereotactic treatment of brain metastases in several French centres. A survey, including three questions about the prescription of irradiation and twenty-one questions about how the ExacTrac ® system is used, was sent to nine French centres owning a dedicated Novalis ® accelerator. Five centres have accepted to participate in the study. All centres checked the positioning before each treatment's bow, with residual mismatch tolerances of 0.5 to 0.7mm for the translations and 0.5 to 1° for the rotations. All centres except one also realised orthogonal planar images of classic incidences to help operators ensure proper isocentre positioning. Prescribed doses were 20Gy in one fraction, 30Gy and 33Gy in three fractions or 34Gy in four fractions, mainly depending on the size of the lesion. Finally, a physician validated the images at the treatment station before starting the irradiation. The practices of the different centres concerning the positioning protocols were rather homogeneous, in agreement with the literature data on ExacTrac ® system's accuracy, as well as proposed fractionations. The systematic medical validation at the treatment station may, however, be questioned because of the waiting time between the doctor's call and validation itself and because of its usefulness; indeed, corrections by the radiation oncologist are very rare and in some centres, non-existent. Copyright © 2016. Published by Elsevier SAS.

Increasing use of less-invasive hemodynamic monitoring in 3 specialty surgical intensive care units: a 5-year experience at a tertiary medical center.

PubMed

Kirton, Orlando C; Calabrese, Rebecca C; Staff, Ilene

2015-01-01

Less-invasive hemodynamic monitoring (eg, esophageal doppler monitoring [EDM] and arterial pressure contour analysis, FloTrac) is increasingly used as an alternative to pulmonary artery catheters (PACs) in critically ill intensive care unit (ICU). The decrease in use of PACs is not associated with increased mortality. Five-year retrospective review of 1894 hemodynamically monitored patients admitted to 3 surgical ICUs in a university-affiliate, tertiary care urban hospital. Data included the number of admissions, diagnosis-related group discharge case mix, length of stay, insertion of monitoring devices (PAC, EDM, and FloTrac probes), administered intravenous vasoactive agents (β-predominant agonists--dobutamine, epinephrine, and dopamine; vasopressors--norepinephrine and phenylephrine), and mortality. Data from hospital administrative databases were compiled to create patient characteristic and monitoring variables across a 5-year time period, 2005 to 2009 inclusive. Chi-square for independent proportions, 1-way analysis of variance, and Kruskal-Wallis tests were used; tests for trend were conducted. An α level of .05 was considered significant. Statistical Package for the Social Sciences v14 was used for all statistical testing. There was a significant change in the type of hemodynamic monitors inserted in 2 of the 3 surgical ICUs (in the general surgery and neurointensive care but not in the cardiac ICU) from PACs to less-invasive devices (FloTrac or EDM) during the 5-year study period (P < .001). There was no change in mortality rate over the time period (P = .492). There was an overall increase in the proportion of monitored patients who received intravenous vasoactive agents (P < .001) with a progressive shift from β-agonists to vasopressors (P < .002). Multivariate analyses indicated that age, case mix, and use of vasoactive agents were all independent predictors of inhospital mortality (P = .001) but that type of monitoring was not (P = .638). In a 5-year period, the decreased insertions of PACs were replaced by increased utilization of less-invasive hemodynamic monitoring devices. This change in practice did not adversely impact mortality. © The Author(s) 2013.

TechTracS: NASA's commercial technology management system

NASA Astrophysics Data System (ADS)

Barquinero, Kevin; Cannon, Douglas

1996-03-01

The Commercial Technology Mission is a primary NASA mission, comparable in importance to those in aeronautics and space. This paper will discuss TechTracS, NASA Commercial Technology Management System that has been put into place in FY 1995 to implement this mission. This system is designed to identify and capture the NASA technologies which have commercial potential into an off-the-shelf database application, and then track the technologies' progress in realizing the commercial potential through collaborations with industry. The management system consists of four stages. The first is to develop an inventory database of the agency's entire technology portfolio and assess it for relevance to the commercial marketplace. Those technologies that are identified as having commercial potential will then be actively marketed to appropriate industries—this is the second stage. The third stage is when a NASA-industry partnership is entered into for the purposes of commercializing the technology. The final stage is to track the technology's success or failure in the marketplace. The collection of this information in TechTracS enables metrics evaluation and can accelerate the establishment on direct contacts between and NASA technologist and an industry technologist. This connection is the beginning of the technology commercialization process.

Is ExacTrac x-ray system an alternative to CBCT for positioning patients with head and neck cancers?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clemente, Stefania; Chiumento, Costanza; Fiorentino, Alba

Purpose: To evaluate the usefulness of a six-degrees-of freedom (6D) correction using ExacTrac robotics system in patients with head-and-neck (HN) cancer receiving radiation therapy.Methods: Local setup accuracy was analyzed for 12 patients undergoing intensity-modulated radiation therapy (IMRT). Patient position was imaged daily upon two different protocols, cone-beam computed tomography (CBCT), and ExacTrac (ET) images correction. Setup data from either approach were compared in terms of both residual errors after correction and punctual displacement of selected regions of interest (Mandible, C2, and C6 vertebral bodies).Results: On average, both protocols achieved reasonably low residual errors after initial correction. The observed differences inmore » shift vectors between the two protocols showed that CBCT tends to weight more C2 and C6 at the expense of the mandible, while ET tends to average more differences among the different ROIs.Conclusions: CBCT, even without 6D correction capabilities, seems preferable to ET for better consistent alignment and the capability to see soft tissues. Therefore, in our experience, CBCT represents a benchmark for positioning head and neck cancer patients.« less

A comparison of two types of running wheel in terms of mouse preference, health, and welfare.

PubMed

Walker, Michael; Mason, Georgia

2018-07-01

Voluntary wheel running occurs in mice of all strains, sexes, and ages. Mice find voluntary wheel running rewarding, and it leads to numerous health benefits. For this reason wheels are used both to enhance welfare and to create models of exercise. However, many designs of running wheel are used. This makes between-study comparisons difficult, as this variability could potentially affect the amount, pattern, and/or intensity of running behaviour, and thence the wheels' effects on welfare and exercise-related changes in anatomy and physiology. This study therefore evaluated two commercially available models, chosen because safe for group-housed mice: Bio Serv®'s "fast-trac" wheel combo and Ware Manufacturing Inc.'s stainless steel mesh 5″ upright wheel. Working with a total of three hundred and fifty one female C57BL/6, DBA/2 and BALB/c mice, we assessed these wheels' relative utilization by mice when access was free; the strength of motivation for each wheel-type when access required crossing an electrified grid; and the impact each wheel had on mouse well-being (inferred from acoustic startle responses and neophobia) and exercise-related anatomical changes (BMI; heart and hind limb masses). Mice ran more on the "fast-trac" wheel regardless of whether both wheel-types were available at once, or only if one was present. In terms of motivation, subjects required to work to access a single wheel worked equally hard for both wheel-types (even if locked and thus not useable for running), but if provided with one working wheel for free and the other type of wheel (again unlocked) accessible via crossing the electrified grid, the "fast-trac" wheel emerged as more motivating, as the Maximum Price Paid for the Ware metal wheel was lower than that paid for the "fast-trac" plastic wheel, at least for C57BL/6s and DBA/2s. No deleterious consequences were noted with either wheel in terms of health and welfare, but only mice with plastic wheels developed significantly larger hearts and hind limbs than control animals with locked wheels. Thus, where differences emerged, Bio Serv®'s "fast-trac" wheel combos appeared to better meet the aims of exercise provision than Ware Manufacturing's steel upright wheels. Copyright © 2018 Elsevier Inc. All rights reserved.

Improved setup and positioning accuracy using a three‐point customized cushion/mask/bite‐block immobilization system for stereotactic reirradiation of head and neck cancer

PubMed Central

Wang, He; Wang, Congjun; Tung, Samuel; Dimmitt, Andrew Wilson; Wong, Pei Fong; Edson, Mark A.; Garden, Adam S.; Rosenthal, David I.; Fuller, Clifton D.; Gunn, Gary B.; Takiar, Vinita; Wang, Xin A.; Luo, Dershan; Yang, James N.; Wong, Jennifer

2016-01-01

The purpose of this study was to investigate the setup and positioning uncertainty of a custom cushion/mask/bite‐block (CMB) immobilization system and determine PTV margin for image‐guided head and neck stereotactic ablative radiotherapy (HN‐SABR). We analyzed 105 treatment sessions among 21 patients treated with HN‐SABR for recurrent head and neck cancers using a custom CMB immobilization system. Initial patient setup was performed using the ExacTrac infrared (IR) tracking system and initial setup errors were based on comparison of ExacTrac IR tracking system to corrected online ExacTrac X‐rays images registered to treatment plans. Residual setup errors were determined using repeat verification X‐ray. The online ExacTrac corrections were compared to cone‐beam CT (CBCT) before treatment to assess agreement. Intrafractional positioning errors were determined using prebeam X‐rays. The systematic and random errors were analyzed. The initial translational setup errors were −0.8±1.3 mm, −0.8±1.6 mm, and 0.3±1.9 mm in AP, CC, and LR directions, respectively, with a three‐dimensional (3D) vector of 2.7±1.4 mm. The initial rotational errors were up to 2.4° if 6D couch is not available. CBCT agreed with ExacTrac X‐ray images to within 2 mm and 2.5°. The intrafractional uncertainties were 0.1±0.6 mm, 0.1±0.6 mm, and 0.2±0.5 mm in AP, CC, and LR directions, respectively, and 0.0∘±0.5°, 0.0∘±0.6°, and −0.1∘±0.4∘ in yaw, roll, and pitch direction, respectively. The translational vector was 0.9±0.6 mm. The calculated PTV margins mPTV(90,95) were within 1.6 mm when using image guidance for online setup correction. The use of image guidance for online setup correction, in combination with our customized CMB device, highly restricted target motion during treatments and provided robust immobilization to ensure minimum dose of 95% to target volume with 2.0 mm PTV margin for HN‐SABR. PACS number(s): 87.55.ne PMID:27167275

Correction to the plant canopy gap-size analysis theory used by the Tracing Radiation and Architecture of Canopies instrument

NASA Astrophysics Data System (ADS)

Leblanc, Sylvain G.

2002-12-01

A plant canopy gap-size analyzer, the Tracing Radiation and Architecture of Canopies (TRAC), developed by Chen and Cihlar [Appl. Opt. 34, 6211 (1995)] and commercialized by 3rd Wave Engineering (Nepean, Canada), has been used around the world to quantify the fraction of photosynthetically active radiation absorbed by plant canopies, the leaf area index (LAI), and canopy architectural parameters. The TRAC is walked under a canopy along transects to measure sunflecks that are converted into a gap-size distribution. A numerical gap-removal technique is performed to remove gaps that are not theoretically possible in a random canopy. The resulting reduced gap-size distribution is used to quantify the heterogeneity of the canopy and to improve LAI measurements. It is explicitly shown here that the original derivation of the clumping index was missing a normalization factor. For a very clumped canopy with a large gap fraction, the resulting LAI can be more than 100% smaller than previously estimated. A test case is used to demonstrate that the new clumping index derivation allows a more accurate change of LAI to be measured.

Development of a video image-based QA system for the positional accuracy of dynamic tumor tracking irradiation in the Vero4DRT system.

PubMed

Ebe, Kazuyu; Sugimoto, Satoru; Utsunomiya, Satoru; Kagamu, Hiroshi; Aoyama, Hidefumi; Court, Laurence; Tokuyama, Katsuichi; Baba, Ryuta; Ogihara, Yoshisada; Ichikawa, Kosuke; Toyama, Joji

2015-08-01

To develop and evaluate a new video image-based QA system, including in-house software, that can display a tracking state visually and quantify the positional accuracy of dynamic tumor tracking irradiation in the Vero4DRT system. Sixteen trajectories in six patients with pulmonary cancer were obtained with the ExacTrac in the Vero4DRT system. Motion data in the cranio-caudal direction (Y direction) were used as the input for a programmable motion table (Quasar). A target phantom was placed on the motion table, which was placed on the 2D ionization chamber array (MatriXX). Then, the 4D modeling procedure was performed on the target phantom during a reproduction of the patient's tumor motion. A substitute target with the patient's tumor motion was irradiated with 6-MV x-rays under the surrogate infrared system. The 2D dose images obtained from the MatriXX (33 frames/s; 40 s) were exported to in-house video-image analyzing software. The absolute differences in the Y direction between the center of the exposed target and the center of the exposed field were calculated. Positional errors were observed. The authors' QA results were compared to 4D modeling function errors and gimbal motion errors obtained from log analyses in the ExacTrac to verify the accuracy of their QA system. The patients' tumor motions were evaluated in the wave forms, and the peak-to-peak distances were also measured to verify their reproducibility. Thirteen of sixteen trajectories (81.3%) were successfully reproduced with Quasar. The peak-to-peak distances ranged from 2.7 to 29.0 mm. Three trajectories (18.7%) were not successfully reproduced due to the limited motions of the Quasar. Thus, 13 of 16 trajectories were summarized. The mean number of video images used for analysis was 1156. The positional errors (absolute mean difference + 2 standard deviation) ranged from 0.54 to 1.55 mm. The error values differed by less than 1 mm from 4D modeling function errors and gimbal motion errors in the ExacTrac log analyses (n = 13). The newly developed video image-based QA system, including in-house software, can analyze more than a thousand images (33 frames/s). Positional errors are approximately equivalent to those in ExacTrac log analyses. This system is useful for the visual illustration of the progress of the tracking state and for the quantification of positional accuracy during dynamic tumor tracking irradiation in the Vero4DRT system.

Cloudy - simulating the non-equilibrium microphysics of gas and dust, and its observed spectrum

NASA Astrophysics Data System (ADS)

Ferland, Gary J.

2014-01-01

Cloudy is an open-source plasma/spectral simulation code, last described in the open-access journal Revista Mexicana (Ferland et al. 2013, 2013RMxAA..49..137F). The project goal is a complete simulation of the microphysics of gas and dust over the full range of density, temperature, and ionization that we encounter in astrophysics, together with a prediction of the observed spectrum. Cloudy is one of the more widely used theory codes in astrophysics with roughly 200 papers citing its documentation each year. It is developed by graduate students, postdocs, and an international network of collaborators. Cloudy is freely available on the web at trac.nublado.org, the user community can post questions on http://groups.yahoo.com/neo/groups/cloudy_simulations/info, and summer schools are organized to learn more about Cloudy and its use (http://cloud9.pa.uky.edu gary/cloudy/CloudySummerSchool/). The code’s widespread use is possible because of extensive automatic testing. It is exercised over its full range of applicability whenever the source is changed. Changes in predicted quantities are automatically detected along with any newly introduced problems. The code is designed to be autonomous and self-aware. It generates a report at the end of a calculation that summarizes any problems encountered along with suggestions of potentially incorrect boundary conditions. This self-monitoring is a core feature since the code is now often used to generate large MPI grids of simulations, making it impossible for a user to verify each calculation by hand. I will describe some challenges in developing a large physics code, with its many interconnected physical processes, many at the frontier of research in atomic or molecular physics, all in an open environment.

Types and Frequency of Infusion Pump Alarms: Protocol for a Retrospective Data Analysis.

PubMed

Glover, Kevin R; Vitoux, Rachel R; Schuster, Catherine; Curtin, Christopher R

2018-06-14

The variety of alarms from all types of medical devices has increased from 6 to 40 in the last three decades, with today's most critically ill patients experiencing as many as 45 alarms per hour. Alarm fatigue has been identified as a critical safety issue for clinical staff that can lead to potentially dangerous delays or nonresponse to actionable alarms, resulting in serious patient injury and death. To date, most research on medical device alarms has focused on the nonactionable alarms of physiological monitoring devices. While there have been some reports in the literature related to drug library alerts during the infusion pump programing sequence, research related to the types and frequencies of actionable infusion pump alarms remains largely unexplored. The objectives of this study protocol are to establish baseline data related to the types and frequency of infusion pump alarms from the B. Braun Outlook 400ES Safety Infusion System with the accompanying DoseTrac Infusion Management Software. The most recent consecutive 60-day period of backup hospital data received between April 2014 and February 2017 from 32 United States-based hospitals will be selected for analysis. Microsoft SQL Server (2012 - 11.0.5343.0 X64) will be used to manage the data with unique code written to sort data and perform descriptive analyses. A validated data management methodology will be utilized to clean and analyze the data. Data management procedures will include blinding, cleaning, and review of existing infusion data within the DoseTrac Infusion Management Software databases at each hospital. Patient-identifying data will be removed prior to merging into a dedicated and secure data repository. This pooled data will then be analyzed. This exploratory study will analyze the aggregate alarm data for each hospital by care area, drug infused, time of day, and day of week, including: overall infusion pump alarm frequency (number of alarms per active infusion), duration of alarms (average, range, median), and type and frequency of alarms distributed by care area. Infusion pump alarm data collected and analyzed in this study will be used to help establish a baseline of infusion pump alarm types and relative frequencies. Understanding the incidences and characteristics of infusion pump alarms will result in more informed quality improvement recommendations to decrease and/or modify infusion pump alarms, and potentially reduce clinical staff alarm fatigue and improve patient safety. . RR1-10.2196/10446. ©Kevin R Glover, Rachel R Vitoux, Catherine Schuster, Christopher R Curtin. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 14.06.2018.

TRAC based sensing for autonomous rendezvous

NASA Technical Reports Server (NTRS)

Everett, Louis J.; Monford, Leo

1991-01-01

The Targeting Reflective Alignment Concept (TRAC) sensor is to be used in an effort to support an Autonomous Rendezvous and Docking (AR&D) flight experiment. The TRAC sensor uses a fixed-focus, fixed-iris CCD camera and a target that is a combination of active and passive components. The system experiment is anticipated to fly in 1994 using two Commercial Experiment Transporters (COMET's). The requirements for the sensor are: bearing error less than or equal to 0.075 deg; bearing error rate less than 0.3 deg/sec; attitude error less than 0.5 deg.; and attitude rate error less than 2.0 deg/sec. The range requirement depends on the range and the range rate of the vehicle. The active component of the target is several 'kilo-bright' LED's that can emit 2500 millicandela with 40 milliwatts of input power. Flashing the lights in a known pattern eliminates background illumination. The system should be able to rendezvous from 300 meters all the way to capture. A question that arose during the presentation: What is the life time of the LED's and their sensitivity to radiation? The LED's should be manufactured to Military Specifications, coated with silicon dioxide, and all other space qualified precautions should be taken. The LED's will not be on all the time so they should easily last the two-year mission.

Microenvironment Tracker (MicroTrac) | Science Inventory ...

EPA Pesticide Factsheets

Epidemiologic studies have shown associations between air pollution concentrations measured at central-site ambient monitors and adverse health outcomes. Using central-site concentrations as exposure surrogates, however, can lead to exposure errors due to time spent in various indoor and outdoor microenvironments (ME) with pollutant concentrations that can be substantially different from central-site concentrations. These exposure errors can introduce bias and incorrect confidence intervals in health effect estimates, which diminish the power of such studies to establish correct conclusions about the exposure and health effects association. The significance of this issue was highlighted in the National Research Council (NRC) Report “Research Priorities for Airborne Particulate Matter”, which recommends that EPA address exposure error in health studies. To address this limitation, we developed MicroTrac, an automated classification model that estimates time of day and duration spent in eight ME (indoors and outdoors at home, work, school; inside vehicles; other locations) from personal global positioning system (GPS) data and geocoded boundaries of buildings (e.g., home, work, school). MicroTrac has several innovative design features: (1) using GPS signal quality to account for GPS signal loss inside certain buildings, (2) spatial buffering of building boundaries to account for the spatial inaccuracy of the GPS device, and (3) temporal buffering of GPS positi

Clinical accuracy of ExacTrac intracranial frameless stereotactic system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ackerly, T.; Lancaster, C. M.; Geso, M.

2011-09-15

Purpose: In this paper, the authors assess the accuracy of the Brainlab ExacTrac system for frameless intracranial stereotactic treatments in clinical practice. Methods: They recorded couch angle and image fusion results (comprising lateral, longitudinal, and vertical shifts, and rotation corrections about these axes) for 109 stereotactic radiosurgery and 166 stereotactic radiotherapy patient treatments. Frameless stereotactic treatments involve iterative 6D image fusion corrections applied until the results conform to customizable pass criteria, theirs being 0.7 mm and 0.5 deg. for each axis. The planning CT slice thickness was 1.25 mm. It has been reported in the literature that the CT slices'more » thickness impacts the accuracy of localization to bony anatomy. The principle of invariance with respect to patient orientation was used to determine spatial accuracy. Results: The data for radiosurgery comprised 927 image pairs, of which 532 passed (pass ratio of 57.4%). The data for radiotherapy comprised 15983 image pairs, of which 10 050 passed (pass ratio of 62.9%). For stereotactic radiotherapy, the combined uncertainty of ExacTrac calibration, image fusion, and intrafraction motion was (95% confidence interval) 0.290-0.302 and 0.306-0.319 mm in the longitudinal and lateral axes, respectively. The combined uncertainty of image fusion and intrafraction motion in the anterior-posterior coordinates was 0.174-0.182 mm. For stereotactic radiosurgery, the equivalent ranges are 0.323-0.393, 0.337-0.409, and 0.231-0.281 mm. The overall spatial accuracy was 1.24 mm for stereotactic radiotherapy (SRT) and 1.35 mm for stereotactic radiosurgery (SRS). Conclusions: The ExacTrac intracranial frameless stereotactic system spatial accuracy is adequate for clinical practice, and with the same pass criteria, SRT is more accurate than SRS. They now use frameless stereotaxy exclusively at their center.« less

Development of a video image-based QA system for the positional accuracy of dynamic tumor tracking irradiation in the Vero4DRT system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ebe, Kazuyu, E-mail: nrr24490@nifty.com; Tokuyama, Katsuichi; Baba, Ryuta

Purpose: To develop and evaluate a new video image-based QA system, including in-house software, that can display a tracking state visually and quantify the positional accuracy of dynamic tumor tracking irradiation in the Vero4DRT system. Methods: Sixteen trajectories in six patients with pulmonary cancer were obtained with the ExacTrac in the Vero4DRT system. Motion data in the cranio–caudal direction (Y direction) were used as the input for a programmable motion table (Quasar). A target phantom was placed on the motion table, which was placed on the 2D ionization chamber array (MatriXX). Then, the 4D modeling procedure was performed on themore » target phantom during a reproduction of the patient’s tumor motion. A substitute target with the patient’s tumor motion was irradiated with 6-MV x-rays under the surrogate infrared system. The 2D dose images obtained from the MatriXX (33 frames/s; 40 s) were exported to in-house video-image analyzing software. The absolute differences in the Y direction between the center of the exposed target and the center of the exposed field were calculated. Positional errors were observed. The authors’ QA results were compared to 4D modeling function errors and gimbal motion errors obtained from log analyses in the ExacTrac to verify the accuracy of their QA system. The patients’ tumor motions were evaluated in the wave forms, and the peak-to-peak distances were also measured to verify their reproducibility. Results: Thirteen of sixteen trajectories (81.3%) were successfully reproduced with Quasar. The peak-to-peak distances ranged from 2.7 to 29.0 mm. Three trajectories (18.7%) were not successfully reproduced due to the limited motions of the Quasar. Thus, 13 of 16 trajectories were summarized. The mean number of video images used for analysis was 1156. The positional errors (absolute mean difference + 2 standard deviation) ranged from 0.54 to 1.55 mm. The error values differed by less than 1 mm from 4D modeling function errors and gimbal motion errors in the ExacTrac log analyses (n = 13). Conclusions: The newly developed video image-based QA system, including in-house software, can analyze more than a thousand images (33 frames/s). Positional errors are approximately equivalent to those in ExacTrac log analyses. This system is useful for the visual illustration of the progress of the tracking state and for the quantification of positional accuracy during dynamic tumor tracking irradiation in the Vero4DRT system.« less

Fermilab Science Education Office - Educators/Teachers

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Search Professional Development and Research Opportunities Prepare for NGSS/Work with Scientists Professional Development Teacher Workshops and Scholarships Teacher Resource Center Research Opportunities TRAC

Rapid Analysis of Energetic and Geo-Materials Using Laser Induced Breakdown Spectroscopy

DTIC Science & Technology

2013-04-01

et al ., Anal Bioanal Chem ( 2006 ) 385, 316. 5. Mohamed, W. T. Y., Prog Phys (2007) 2, 42. 6. Elhassan, A., et al ., Spectrochim Acta B (2008) 63...Anal (2005) 5, 21. 20. Anzano, J. M., et al ., Anal Chim Acta ( 2006 ) 575, 230. 21. Rusak, D. A., et al ., TrAC Trend Anal Chem (1998) 17, 453. 22. Martin...Spectrosc Reviews (2004) 39, 27. 25. Winefordner, J. D., et al ., J Anal Atom Spectrom (2004) 19, 1061. 26. Cremers , D. A., and Radziemski, L. J.,

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thakur, Gautam

A data-driven realistic design and evalua- tion of vehicular mobility has been particularly chal- lenging due to a lack of large-scale real-world mea- surements in the research community. Current research methodologies rely on articial scenarios, random con- nectivity, and use small and biased samples. In this pa- per, we perform a combined study to learn the struc- ture and connectivity of urban streets and modeling and characterization of vehicular trac densities on them. Our dataset is a collection of more than 222 thousand routes and 25 million vehicular mobility images from 1091 online web cameras located in six dierent re-more » gions of the world. Our results centered around four major observations: i. study shows that driving routes and visiting locations of regions demonstrate power-law distribution, indicating a planned or recently designed road infrastructure; ii. we represent regions by network graphs in which nodes are camera locations and edges are urban streets that connect the nodes. Such represen- tation exhibits small world properties with short path lengths and large clustering coecient; iii. trac densi- ties show 80% temporal correlation during several hours of a day; iv. modeling trac densities against known theoretical distributions show less than 5% deviation for heavy-trailed models such as log-logistic and log- gamma distributions. We believe this work will provide a much-needed contribution to the research community for design and evaluation of future vehicular networks and smart cities.« less

Biotechnological approach for systemic delivery of membrane Receptor Activator of NF-κB Ligand (RANKL) active domain into the circulation

PubMed Central

Cappariello, Alfredo; Paone, Riccardo; Maurizi, Antonio; Capulli, Mattia; Rucci, Nadia; Muraca, Maurizio; Teti, Anna

2015-01-01

Deficiency of Receptor Activator of NF-κB Ligand (RANKL) prevents osteoclast formation causing osteopetrosis. RANKL is a membrane-bound protein cleaved into active soluble (s)RANKL by metalloproteinase 14 (MMP14). We created a bio-device that harbors primary osteoblasts, cultured on 3D hydroxyapatite scaffolds carrying immobilized MMP14 catalytic domain. Scaffolds were sealed in diffusion chambers and implanted in RANKL-deficient mice. Mice received 1 or 2 diffusion chambers, once or twice and were sacrificed after 1 or 2 months from implants. A progressive increase of body weight was observed in the implanted groups. Histological sections of tibias of non-implanted mice were negative for the osteoclast marker Tartrate-Resistant Acid Phosphatase (TRAcP), consistent with the lack of osteoclasts. In contrast, tibias excised from implanted mice showed TRAcP-positive cells in the bone marrow and on the bone surface, these latter morphologically similar to mature osteoclasts. In mice implanted with 4 diffusion chambers total, we noted the highest number and size of TRAcP-positive cells, with quantifiable eroded bone surface and significant reduction of trabecular bone volume. These data demonstrate that our bio-device delivers effective sRANKL, inducing osteoclastogenesis in RANKL-deficient mice, supporting the feasibility of an innovative experimental strategy to treat systemic cytokine deficiencies. PMID:25678116

Biotechnological approach for systemic delivery of membrane Receptor Activator of NF-κB Ligand (RANKL) active domain into the circulation.

PubMed

Cappariello, Alfredo; Paone, Riccardo; Maurizi, Antonio; Capulli, Mattia; Rucci, Nadia; Muraca, Maurizio; Teti, Anna

2015-04-01

Deficiency of Receptor Activator of NF-κB Ligand (RANKL) prevents osteoclast formation causing osteopetrosis. RANKL is a membrane-bound protein cleaved into active soluble (s)RANKL by metalloproteinase 14 (MMP14). We created a bio-device that harbors primary osteoblasts, cultured on 3D hydroxyapatite scaffolds carrying immobilized MMP14 catalytic domain. Scaffolds were sealed in diffusion chambers and implanted in RANKL-deficient mice. Mice received 1 or 2 diffusion chambers, once or twice and were sacrificed after 1 or 2 months from implants. A progressive increase of body weight was observed in the implanted groups. Histological sections of tibias of non-implanted mice were negative for the osteoclast marker Tartrate-Resistant Acid Phosphatase (TRAcP), consistent with the lack of osteoclasts. In contrast, tibias excised from implanted mice showed TRAcP-positive cells in the bone marrow and on the bone surface, these latter morphologically similar to mature osteoclasts. In mice implanted with 4 diffusion chambers total, we noted the highest number and size of TRAcP-positive cells, with quantifiable eroded bone surface and significant reduction of trabecular bone volume. These data demonstrate that our bio-device delivers effective sRANKL, inducing osteoclastogenesis in RANKL-deficient mice, supporting the feasibility of an innovative experimental strategy to treat systemic cytokine deficiencies. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

EYE-TRAC: monitoring attention and utility for mTBI

NASA Astrophysics Data System (ADS)

Maruta, Jun; Tong, Jianliang; Lee, Stephanie W.; Iqbal, Zarah; Schonberger, Alison; Ghajar, Jamshid

2012-06-01

Attention is a core function in cognition and also the most prevalent cognitive deficit in mild traumatic brain injury (mTBI). Predictive timing is an essential element of attention functioning because sensory processing and execution of goal-oriented behavior are facilitated by temporally accurate prediction. It is hypothesized that impaired synchronization between prediction and external events accounts for the attention deficit in mTBI. Other cognitive and somatic or affective symptoms associated with mTBI may be explained as secondary consequences of impaired predictive timing. Eye-Tracking Rapid Attention Computation (EYE-TRAC) is the quantification of predictive timing with indices of dynamic visuo-motor synchronization (DVS) between the gaze and the target during continuous predictive visual tracking. Such quantification allows for cognitive performance monitoring in comparison to the overall population as well as within individuals over time. We report preliminary results of normative data and data collected from subjects with a history of mTBI within 2 weeks of injury and post-concussive symptoms at the time of recruitment. A substantial proportion of mTBI subjects demonstrated DVS scores worse than 95% of normal subjects. In addition, longitudinal monitoring of acute mTBI subjects showed that initially abnormal DVS scores were followed by improvement toward the normal range. In summary, EYE-TRAC provides fast and objective indices of DVS that allow comparison of attention performance to a normative standard and monitoring of within-individual changes.

IJS procedure for RELAP5 to TRACE input model conversion using SNAP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prosek, A.; Berar, O. A.

2012-07-01

The TRAC/RELAP Advanced Computational Engine (TRACE) advanced, best-estimate reactor systems code developed by the U.S. Nuclear Regulatory Commission comes with a graphical user interface called Symbolic Nuclear Analysis Package (SNAP). Much of efforts have been done in the past to develop the RELAP5 input decks. The purpose of this study is to demonstrate the Institut 'Josef Stefan' (IJS) conversion procedure from RELAP5 to TRACE input model of BETHSY facility. The IJS conversion procedure consists of eleven steps and is based on the use of SNAP. For calculations of the selected BETHSY 6.2TC test the RELAP5/MOD3.3 Patch 4 and TRACE V5.0more » Patch 1 were used. The selected BETHSY 6.2TC test was 15.24 cm equivalent diameter horizontal cold leg break in the reference pressurized water reactor without high pressure and low pressure safety injection. The application of the IJS procedure for conversion of BETHSY input model showed that it is important to perform the steps in proper sequence. The overall calculated results obtained with TRACE using the converted RELAP5 model were close to experimental data and comparable to RELAP5/MOD3.3 calculations. Therefore it can be concluded, that proposed IJS conversion procedure was successfully demonstrated on the BETHSY integral test facility input model. (authors)« less

OpenElectrophy: An Electrophysiological Data- and Analysis-Sharing Framework

PubMed Central

Garcia, Samuel; Fourcaud-Trocmé, Nicolas

2008-01-01

Progress in experimental tools and design is allowing the acquisition of increasingly large datasets. Storage, manipulation and efficient analyses of such large amounts of data is now a primary issue. We present OpenElectrophy, an electrophysiological data- and analysis-sharing framework developed to fill this niche. It stores all experiment data and meta-data in a single central MySQL database, and provides a graphic user interface to visualize and explore the data, and a library of functions for user analysis scripting in Python. It implements multiple spike-sorting methods, and oscillation detection based on the ridge extraction methods due to Roux et al. (2007). OpenElectrophy is open source and is freely available for download at http://neuralensemble.org/trac/OpenElectrophy. PMID:19521545

TH-A-9A-05: Initial Setup Accuracy Comparison Between Frame-Based and Frameless Stereotactic Radiosurgery

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tseng, T; Sheu, R; Todorov, B

2014-06-15

Purpose: To evaluate initial setup accuracy for stereotactic radiosurgery (SRS) between Brainlab frame-based and frameless immobilization system, also to discern the magnitude frameless system has on setup parameters. Methods: The correction shifts from the original setup were compared for total 157 SRS cranial treatments (69 frame-based vs. 88 frameless). All treatments were performed on a Novalis linac with ExacTrac positioning system. Localization box with isocenter overlay was used for initial setup and correction shift was determined by ExacTrac 6D auto-fusion to achieve submillimeter accuracy for treatment. For frameless treatments, mean time interval between simulation and treatment was 5.7 days (rangemore » 0–13). Pearson Chi-Square was used for univariate analysis. Results: The correctional radial shifts (mean±STD, median) for the frame and frameless system measured by ExacTrac were 1.2±1.2mm, 1.1mm and 3.1±3.3mm, 2.0mm, respectively. Treatments with frameless system had a radial shift >2mm more often than those with frames (51.1% vs. 2.9%; p<.0001). To achieve submillimeter accuracy, 85.5% frame-based treatments did not require shift and only 23.9% frameless treatment could succeed with initial setup. There was no statistical significant system offset observed in any direction for either system. For frameless treatments, those treated ≥ 3 days from simulation had statistically higher rates of radial shifts between 1–2mm and >2mm compared to patients treated in a shorter amount of time from simulation (34.3% and 56.7% vs. 28.6% and 33.3%, respectively; p=0.006). Conclusion: Although image-guided positioning system can also achieve submillimeter accuracy for frameless system, users should be cautious regarding the inherent uncertainty of its capability of immobilization. A proper quality assurance procedure for frameless mask manufacturing and a protocol for intra-fraction imaging verification will be crucial for frameless system. Time interval between simulation and treatment was influential to initial setup accuracy. A shorter time frame for frameless SRS treatment could be helpful in minimizing uncertainties in localization.« less

Evaluation of stroke volume variation obtained by arterial pulse contour analysis to predict fluid responsiveness intraoperatively.

PubMed

Lahner, D; Kabon, B; Marschalek, C; Chiari, A; Pestel, G; Kaider, A; Fleischmann, E; Hetz, H

2009-09-01

Fluid management guided by oesophageal Doppler monitor has been reported to improve perioperative outcome. Stroke volume variation (SVV) is considered a reliable clinical predictor of fluid responsiveness. Consequently, the aim of the present trial was to evaluate the accuracy of SVV determined by arterial pulse contour (APCO) analysis, using the FloTrac/Vigileo system, to predict fluid responsiveness as measured by the oesophageal Doppler. Patients undergoing major abdominal surgery received intraoperative fluid management guided by oesophageal Doppler monitoring. Fluid boluses of 250 ml each were administered in case of a decrease in corrected flow time (FTc) to <350 ms. Patients were connected to a monitoring device, obtaining SVV by APCO. Haemodynamic variables were recorded before and after fluid bolus application. Fluid responsiveness was defined as an increase in stroke volume index >10%. The ability of SVV to predict fluid responsiveness was assessed by calculation of the area under the receiver operating characteristic (ROC) curve. Twenty patients received 67 fluid boluses. Fifty-two of the 67 fluid boluses administered resulted in fluid responsiveness. SVV achieved an area under the ROC curve of 0.512 [confidence interval (CI) 0.32-0.70]. A cut-off point for fluid responsiveness was found for SVV > or =8.5% (sensitivity: 77%; specificity: 43%; positive predictive value: 84%; and negative predictive value: 33%). This prospective, interventional observer-blinded study demonstrates that SVV obtained by APCO, using the FloTrac/Vigileo system, is not a reliable predictor of fluid responsiveness in the setting of major abdominal surgery.

SU-F-J-25: Position Monitoring for Intracranial SRS Using BrainLAB ExacTrac Snap Verification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jang, S; McCaw, T; Huq, M

2016-06-15

Purpose: To determine the accuracy of position monitoring with BrainLAB ExacTrac snap verification following couch rotations during intracranial SRS. Methods: A CT scan of an anthropomorphic head phantom was acquired using 1.25mm slices. The isocenter was positioned near the centroid of the frontal lobe. The head phantom was initially aligned on the treatment couch using cone-beam CT, then repositioned using ExacTrac x-ray verification with residual errors less than 0.2mm and 0.2°. Snap verification was performed over the full range of couch angles in 15° increments with known positioning offsets of 0–3mm applied to the phantom along each axis. At eachmore » couch angle, the smallest tolerance was determined for which no positioning deviation was detected. Results: For couch angles 30°–60° from the center position, where the longitudinal axis of the phantom is approximately aligned with the beam axis of one x-ray tube, snap verification consistently detected positioning errors exceeding the maximum 8mm tolerance. Defining localization error as the difference between the known offset and the minimum tolerance for which no deviation was detected, the RMS error is mostly less than 1mm outside of couch angles 30°–60° from the central couch position. Given separate measurements of patient position from the two imagers, whether to proceed with treatment can be determined by the criterion of a reading within tolerance from just one (OR criterion) or both (AND criterion) imagers. Using a positioning tolerance of 1.5mm, snap verification has sensitivity and specificity of 94% and 75%, respectively, with the AND criterion, and 67% and 93%, respectively, with the OR criterion. If readings exceeding maximum tolerance are excluded, the sensitivity and specificity are 88% and 86%, respectively, with the AND criterion. Conclusion: With a positioning tolerance of 1.5mm, ExacTrac snap verification can be used during intracranial SRS with sensitivity and specificity between 85% and 90%.« less

About Us

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Atoll Cleanup Documents TRAC About Who We Are Our Values History Locations Our Leadership Director Who We Are Our Values Locations DTRA Leadership Stay Connected About DoD Top Issues News Photos &

75 FR 35878 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-23

...: Tip Reporting Alternative Commitment (TRAC) for Use in the Food and Beverage Industry. Abstract...., Room 6129, Washington, DC 20224; (202) 622-3634. OMB Reviewer: Shagufta Ahmed, Office of Management and...

Defense Threat Reduction Agency > About > Our Values

Science.gov Websites

Atoll Cleanup Documents TRAC About Who We Are Our Values History Locations Our Leadership Director Our Values Locations DTRA Leadership Stay Connected About DoD Top Issues News Photos & Videos

Gun Transparency and Accountability (Gun TRAC) Act of 2013

THOMAS, 113th Congress

Rep. Speier, Jackie [D-CA-14

2013-01-25

House - 02/28/2013 Referred to the Subcommittee on Crime, Terrorism, Homeland Security, And Investigations. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection

PubMed Central

Eyquem, Justin; Mansilla-Soto, Jorge; Giavridis, Theodoros; van der Stegen, Sjoukje J. C.; Hamieh, Mohamad; Cunanan, Kristen M.; Odak, Ashlesha; Gönen, Mithat; Sadelain, Michel

2017-01-01

Chimeric antigen receptors (CARs) are synthetic receptors that redirect and reprogram T cells to mediate tumour rejection1. The most successful CARs used to date are those targeting CD19 (ref. 2), which offer the prospect of complete remission in patients with chemorefractory or relapsed B-cell malignancies3. CARs are typically transduced into the T cells of a patient using γ-retroviral4 vectors or other randomly integrating vectors5, which may result in clonal expansion, oncogenic transformation, variegated transgene expression and transcriptional silencing6–8. Recent advances in genome editing enable efficient sequence-specific interventions in human cells9,10, including targeted gene delivery to the CCR5 and AAVS1 loci11,12. Here we show that directing a CD19-specific CAR to the T-cell receptor α constant (TRAC) locus not only results in uniform CAR expression in human peripheral blood T cells, but also enhances T-cell potency, with edited cells vastly outperforming conventionally generated CAR T cells in a mouse model of acute lymphoblastic leukaemia. We further demonstrate that targeting the CAR to the TRAC locus averts tonic CAR signalling and establishes effective internalization and re-expression of the CAR following single or repeated exposure to antigen, delaying effector T-cell differentiation and exhaustion. These findings uncover facets of CAR immunobiology and underscore the potential of CRISPR/Cas9 genome editing to advance immunotherapies. PMID:28225754

Microenvironment Tracker (MicroTrac)

EPA Science Inventory

Epidemiologic studies have shown associations between air pollution concentrations measured at central-site ambient monitors and adverse health outcomes. Using central-site concentrations as exposure surrogates, however, can lead to exposure errors due to time spent in various in...

75 FR 11632 - Proposed Collection; Comment Request for Notice 2001-1

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-11

... comments concerning Notice 2001-1, Employer-designed Tip Reporting Program for the Food and Beverage... Reporting Program for the Food and Beverage Industry (EmTRAC). OMB Number: 1545-1716. Notice Number: Notice...

Statistical Representations of Track Geometry : Volume I, Text.

DOT National Transportation Integrated Search

1980-03-31

Mathematical representations of railroad track geometry variations are derived from time series analyses of track measurements. Since the majority of track is free of anomalies (turnouts, crossings, bridges, etc.), representation of anomaly-free trac...

76 FR 21033 - Core Industries, Inc., DBA Star Trac, Including On-Site Leased Workers From Aerotek, Helpmates...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-14

... for workers of the subject firm. The workers produce commercial fitness equipment. The Murrieta... the overall production operation and were affected by the firm's acquisition of commercial fitness...

Performance evaluation and specification of trackless tack.

DOT National Transportation Integrated Search

2016-09-01

Several trackless tack products have come to market in Texas; however, there are currently no specifications to : ensure the products have trackless properties and adequate bond strength. The objectives of this project were to : (1) evaluate the trac...

Review of private sector data for roadway monitoring

DOT National Transportation Integrated Search

2007-05-01

This document presents a summary of Washington State Transportation Center's (TRACs) examination of privately collected roadway performance data in the Puget Sound Region. The review examined the accuracy and reliability of those data for use by W...

RANKL/Osteoprotegerin System and Bone Turnover in Hashimoto Thyroiditis.

PubMed

Konca Degertekin, Ceyla; Turhan Iyidir, Ozlem; Aktas Yılmaz, Banu; Elbeg, Sehri; Pasaoglu, Ozge Tugce; Pasaoglu, Hatice; Cakır, Nuri; Arslan, Metin

2016-10-01

Hypothyroidism is associated with changes in bone metabolism. The impact of hypothyroidism and the associated autoimmunity on the mediators of bone turnover in Hashimoto's thyroiditis (HT) is not known. In this study, we assessed the levels of OPG, RANKL, and IL-6 along with markers of bone formation as osteocalcin (OC) and markers of bone resorption as type 1 collagen C telopeptide (CTX) and tartrate-resistant acid phosphatase isoform 5b (TRAcP 5b) in 30 hypothyroid and 30 euthyroid premenopausal HT patients and 20 healthy premenopausal controls. We found that TRAcP 5b (p = 0.006), CTX (p = 0.01), OC (p = 0.017), and IL-6 (p < 0.001) levels were lower in the hypothyroid group compared to euthyroid HT patients and controls. OPG levels were higher (p < 0.001) and RANKL levels were lower (p = 0.021) in hypothyroid and euthyroid HT patients compared to controls. TSH was negatively correlated with IL-6 (rho = -0.434, p < 0.001), OC (rho = -0.313, p = 0.006), TRAcP 5b (rho = -0.335, p = 0.003), and positively correlated with OPG (rho = 0.248, p = 0.029). RANKL/OPG ratio was independently associated with the presence of HT. In conclusion, bone turnover is slowed down by hypothyroidism in premenopausal patients with HT. Thyroid autoimmunity might have a unique impact on OPG/RANKL levels apart from the resultant hypothyroidism.

INTEGRATIVE SAMPLING OF ANTIBIOTICS AND OTHER PHARMACEUTICALLY-RELATED COMPOUNDS

EPA Science Inventory

Pharmaceuticals from human and veterinary use continually enter the environment through municipal wastewater treatment plants (WWTPs), surface runoff from animal waste, and direct disposal of unused medications. The presence of these chemicals, albeit often at subtherapeutic trac...

iTRAC : intelligent video compression for automated traffic surveillance systems.

DOT National Transportation Integrated Search

2010-08-01

Non-intrusive video imaging sensors are commonly used in traffic monitoring : and surveillance. For some applications it is necessary to transmit the video : data over communication links. However, due to increased requirements of : bitrate this mean...

PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data.

PubMed

Zhang, Yanju; Lameijer, Eric-Wubbo; 't Hoen, Peter A C; Ning, Zemin; Slagboom, P Eline; Ye, Kai

2012-02-15

RNA-seq is a powerful technology for the study of transcriptome profiles that uses deep-sequencing technologies. Moreover, it may be used for cellular phenotyping and help establishing the etiology of diseases characterized by abnormal splicing patterns. In RNA-Seq, the exact nature of splicing events is buried in the reads that span exon-exon boundaries. The accurate and efficient mapping of these reads to the reference genome is a major challenge. We developed PASSion, a pattern growth algorithm-based pipeline for splice site detection in paired-end RNA-Seq reads. Comparing the performance of PASSion to three existing RNA-Seq analysis pipelines, TopHat, MapSplice and HMMSplicer, revealed that PASSion is competitive with these packages. Moreover, the performance of PASSion is not affected by read length and coverage. It performs better than the other three approaches when detecting junctions in highly abundant transcripts. PASSion has the ability to detect junctions that do not have known splicing motifs, which cannot be found by the other tools. Of the two public RNA-Seq datasets, PASSion predicted ≈ 137,000 and 173,000 splicing events, of which on average 82 are known junctions annotated in the Ensembl transcript database and 18% are novel. In addition, our package can discover differential and shared splicing patterns among multiple samples. The code and utilities can be freely downloaded from https://trac.nbic.nl/passion and ftp://ftp.sanger.ac.uk/pub/zn1/passion.

Multiloop Integral System Test (MIST): MIST Facility Functional Specification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Habib, T F; Koksal, C G; Moskal, T E

1991-04-01

The Multiloop Integral System Test (MIST) is part of a multiphase program started in 1983 to address small-break loss-of-coolant accidents (SBLOCAs) specific to Babcock and Wilcox designed plants. MIST is sponsored by the US Nuclear Regulatory Commission, the Babcock Wilcox Owners Group, the Electric Power Research Institute, and Babcock and Wilcox. The unique features of the Babcock and Wilcox design, specifically the hot leg U-bends and steam generators, prevented the use of existing integral system data or existing integral facilities to address the thermal-hydraulic SBLOCA questions. MIST was specifically designed and constructed for this program, and an existing facility --more » the Once Through Integral System (OTIS) -- was also used. Data from MIST and OTIS are used to benchmark the adequacy of system codes, such as RELAP5 and TRAC, for predicting abnormal plant transients. The MIST Functional Specification documents as-built design features, dimensions, instrumentation, and test approach. It also presents the scaling basis for the facility and serves to define the scope of work for the facility design and construction. 13 refs., 112 figs., 38 tabs.« less

Effect of planecta and ROSE™ on the frequency characteristics of blood pressure-transducer kits.

PubMed

Fujiwara, Shigeki; Kawakubo, Yoshifumi; Mori, Satoshi; Tachihara, Keiichi; Toyoguchi, Izumi; Yokoyama, Takeshi

2015-12-01

Pressure-transducer kits have frequency characteristics such as natural frequency and damping coefficient, which affect the monitoring accuracy. The aim of the present study was to investigate the effect of planecta ports and a damping device (ROSE™, Argon Medical Devices, TX, USA) on the frequency characteristics of pressure-transducer kits. The FloTrac sensor kit (Edwards Lifesciences, CA, USA) and the DTXplus transducer kit (Argon Medical Devices) were prepared with planecta ports, and their frequency characteristics were tested with or without ROSE™. The natural frequency and damping coefficient of each kit were obtained using frequency characteristics analysis software and evaluated by plotting them on the Gardner's chart. By inserting a planecta port, the natural frequency markedly decreased in both the FloTrac sensor kit (from 40 to 22 Hz) and the DTXplus transducer kit (from 35 to 22 Hz). In both kits with one planecta port, the damping coefficient markedly increased by insertion of ROSE™ from 0.2 to 0.5, optimising frequency characteristics. In both kits with two planecta ports, however, the natural frequency decreased from 22 to 12 Hz. The damping coefficient increased from 0.2 to 0.8 by insertion of ROSE™; however, optimisation was not achieved even by ROSE™ insertion. Planecta ports decrease the natural frequency of the kit. ROSE™ is useful to optimise the frequency characteristics in the kits without or with one planecta port. However, optimisation is difficult with two or more planecta ports, even with the ROSE™ device.

Online Databases. Ingenta Grows in the U.S. Market.

ERIC Educational Resources Information Center

Tenopir, Carol

2002-01-01

Focuses on the growth of the United Kingdom company Ingenta in the United States. Highlights include a new partnership with Gale Group related to their InfoTrac databases; indexing and full text coverage; standards; and other Ingenta acquisitions. (LRW)

76 FR 73596 - Notice of Scope Rulings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

... LLC and OTR Wheel Engineering, Inc.; its wheel hub units/assemblies with tapered roller bearings are...-601: Tapered Roller Bearings from the People's Republic of China Requestor: New Trend Engineering... Requestor: OTR Wheel Engineering, Inc. (``OTR Wheel''); whether OTR Wheel's ``Trac Master'' and ``Traction...

77 FR 32648 - Proposed Collection; Comment Request; CareerTrac

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-01

... of 1995, the Fogarty International Center (FIC), National Institute of Environmental Health Sciences...) within NIEHS, National Institute of General Medical Science (NIGMS), and National Cancer Institute (NCI... outcomes are achieved, comply with OMB Part requirements, respond to congressional inquiries, and as a...

FGC Webinar: Making it Easier to Buy Greener Products and Services, and Final FGC Data Reporting

EPA Pesticide Factsheets

Presention on changes in Sustainable Facility Tool, Green Product Compilation, and Environmental Programs pages that clarify requirements for purchasing products and services, as well as reporting your FY2017 FGC Data using Re-TRAC Connect.

Measurement Program for Evaluation of Concrete Ties and Fastenings in Transit Track

DOT National Transportation Integrated Search

1979-03-01

This report outlines a measurement program to obtain data on the performance of standard tie designs and associated fastening systems under field service conditions. In addition, the program identifies limited data to be obtained from a wood tie trac...

Comparison of two combinations of opioid and non-opioid analgesics for acute periradicular abscess: a randomized clinical trial.

PubMed

Santini, Manuela Favarin; Rosa, Ricardo Abreu da; Ferreira, Maria Beatriz Cardoso; Fischer, Maria Isabel; Souza, Erick Miranda; Só, Marcus Vinícius Reis

2017-01-01

Acute periradicular abscess is a condition characterized by the formation and propagation of pus in the periapical tissues and generally associated with debilitating pain. The aim of this study was to compare the overall analgesic effectiveness of two combinations of opioid and non-opioid analgesics for acute periradicular abscess. This study included 26 patients who sought emergency care in a Brazilian dental school. The patients were randomly divided into two groups: Co/Ac - oral prescription of codeine (30 mg) plus acetaminophen (500 mg), every 4 h, for 3 days or Tr/Ac - oral prescription of tramadol hydrochloride (37.5 mg) plus acetaminophen (500 mg) on the same schedule. Two factors were evaluated: (1) pain scores recorded by the patients in a pain diary 6, 12, 24, 48, and 72 h after treatment, using the Visual Analogue Scale; and (2) the occurrence of adverse effects. In both groups, there was a reduction in pain scores over time. For the Co/Ac group, there was a significant reduction in the scores 12, 24, 48, and 72 hours after treatment (P<0.05). In the Tr/Ac group, the scores significantly decreased over time from time point 6 h (P<0.05). Comparing the pain at each time point, the groups were not significantly different (P>0.05), i.e., both treatments were effective in controlling pain caused by APA; however, the combination of Tr/Ac caused more adverse reactions as two patients had to stop using the medication. This study suggests that, considering both analgesic efficacy and safety, the combination of codeine and acetaminophen is more effective to control moderate to severe pain from acute periradicular abscesses.

Pheromone-Regulated Expression of Sex Pheromone Plasmid pAD1-Encoded Aggregation Substance Depends on at Least Six Upstream Genes and a cis-Acting, Orientation-Dependent Factor

PubMed Central

Muscholl-Silberhorn, Albrecht B.

2000-01-01

Conjugative transfer of Enterococcus faecalis-specific sex pheromone plasmids relies on an adhesin, called aggregation substance, to confer a tight cell-to-cell contact between the mating partners. To analyze the dependence of pAD1-encoded aggregation substance, Asa1, on pheromone induction, a variety of upstream fragments were fused to an α-amylase reporter gene, amyL, by use of a novel promoter probe vector, pAMY-em1. For pheromone-regulated α-amylase activity, a total of at least six genes, traB, traC, traA, traE1, orfY, and orf1, are required: TraB efficiently represses asa1 (by a mechanism unrelated to its presumptive function in pheromone shutdown, since a complete shutdown is observed exclusively in the presence of traC); only traC can relieve traB-mediated repression in a pheromone-dependent manner. In addition to traB, traA is required but not sufficient for negative control. Mutational inactivation of traE1, orfY, or orf1, respectively, results in a total loss of α-amylase activity for constructs normally mediating constitutive expression. Inversion of a fragment covering traA, P0, and traE1 without disrupting any gene or control element switches off amyL or asa1 expression, indicating the involvement of a cis-acting, orientation-dependent factor (as had been shown for plasmid pCF10). Unexpectedly, pAD1 represses all pAMY-em1 derivatives in trans, while its own pheromone-dependent functions are unaffected. The discrepancy between the new data and those of former studies defining TraE1 as a trans-acting positive regulator is discussed. PMID:10850999

Driver response to the TetraStar Navigation Assistance System by age and sex

DOT National Transportation Integrated Search

1997-07-01

This study is part of the evaluation of the FAST-TRAC operational test of an Intelligent Transportation System (ITS) in Michigan and is concerned with user perceptions and behaviors with Advanced Traveler Information Systems (ATIS). The use and perce...

MONITORING OF WATERWAYS FOR EMERGING CONTAMINANTS USING INTEGRATIVE SAMPLING COUPLED WITH LIQUID CHROMATOGRAPHY-ELECTROSPRAY/MASS SPECTROMETRY

EPA Science Inventory

Assessing the potential impact to the aquatic environment from emerging contaminants, entails monitoring a complex mixture (pharmaceuticals, polar pesticides, industrial by- products and degradation products) in natural waters. The presence of these chemicals, often at ultra-trac...

Dynamic travel information personalized and delivered to your cell phone : addendum.

DOT National Transportation Integrated Search

2011-03-01

Real-time travel information must reach a significant amount of travelers to create a large amount of travel behavior change. For this project, since the TRAC-IT mobile phone application is used to monitor user context in terms of location, the mobil...

Human Health Risk Assessment: A case study application of principles in dose response assessment

EPA Science Inventory

This case study application workshop will build on fundamental concepts and techniques in risk assessment presented and archived at previous TRAC meeting workshops. Practical examples from publicly available, peer reviewed risk assessments will be used as teaching aids. Course ...

Measuring Impact of EPAs Computational Toxicology Research (BOSC)

EPA Science Inventory

Computational Toxicology (CompTox) research at the EPA was initiated in 2005. Since 2005, CompTox research efforts have made tremendous advances in developing new approaches to evaluate thousands of chemicals for potential health effects. The purpose of this case study is to trac...

Genetic algorithm-based stochastic optimization for preempted signals at highway railroad grade crossing.

DOT National Transportation Integrated Search

2013-09-01

Decreasing the number of accidents at highway-railway grade crossings (HRGCs) is an important goal in the transportation field. The preemption of traffic signal operations at HRGCs is widely used to prevent accidents by clearing vehicles off the trac...

A description of QUALCOMM Automatic Satellite Position Reporting (QASPR(R)) for mobile communications

NASA Technical Reports Server (NTRS)

Ames, William G.

1990-01-01

Two satellite position reporting has been introduced into the OmniTRACS mobile satellite communication system. This system significantly improves position reporting reliability and accuracy while simplifying the terminal's hardware. The positioning technique uses the original OmniTRACS TDMA timing signal formats in the forward and return link directions plus an auxiliary, low power forward link signal through a second satellite to derive distance values. The distances are then converted into the mobile terminal's latitude and longitude in real time. A minor augmentation of the spread spectrum profile of the return link allowed the resolution of periodic ambiguities. The system also locates the two satellites in real time with fixed platforms in known locations using identical mobile terminal hardware. Initial accuracies of 1/4 mile have been realized uniformly throughout the USA using a satellite separation of 22 degrees and there are no dead zones, skywaves, or cycle slips as found in terrestrial systems like LORAN-C.

A description of QUALCOMM Automatic Satellite Position Reporting (QASPR(R)) for mobile communications

NASA Astrophysics Data System (ADS)

Ames, William G.

Two satellite position reporting has been introduced into the OmniTRACS mobile satellite communication system. This system significantly improves position reporting reliability and accuracy while simplifying the terminal's hardware. The positioning technique uses the original OmniTRACS TDMA timing signal formats in the forward and return link directions plus an auxiliary, low power forward link signal through a second satellite to derive distance values. The distances are then converted into the mobile terminal's latitude and longitude in real time. A minor augmentation of the spread spectrum profile of the return link allowed the resolution of periodic ambiguities. The system also locates the two satellites in real time with fixed platforms in known locations using identical mobile terminal hardware. Initial accuracies of 1/4 mile have been realized uniformly throughout the USA using a satellite separation of 22 degrees and there are no dead zones, skywaves, or cycle slips as found in terrestrial systems like LORAN-C.

Poria cocos polysaccharide attenuates RANKL-induced osteoclastogenesis by suppressing NFATc1 activity and phosphorylation of ERK and STAT3.

PubMed

Song, Dezhi; Cao, Zhen; Tickner, Jennifer; Qiu, Heng; Wang, Chao; Chen, Kai; Wang, Ziyi; Guo, Chunyu; Dong, Shiwu; Xu, Jiake

2018-06-01

Pathological fractures caused by osteolytic lesions seriously threaten the health of patients. Osteoclasts play important roles in bone resorption whose hyperfunction are closely related to osteolytic lesions. Studies on osteoclast differentiation and function assist in the prevention of excessive bone loss associated diseases. We screened a variety of natural compounds with anti-inflammatory effect and found that poria cocos polysaccharide (PCP) inhibited RANKL-induced osteoclast formation and bone resorption via TRAcP staining, immunofluorescence, RT-PCR and western blot. PCP down-regulated phosphorylation of STAT3, P38, ERK and JNK, and thus repressed the expression of NFAcT1 and c-Fos during RANKL-induced osteoclastogenesis. Besides, the expression of bone resorption related genes such as TRAcP and CTSK was suppressed by PCP. The results suggest that PCP can be invoked as a candidate for the treatment of osteolytic diseases by inhibiting osteoclastogenesis. Copyright © 2018 Elsevier Inc. All rights reserved.

Fast time-resolved aerosol collector: proof of concept

NASA Astrophysics Data System (ADS)

Yu, X.-Y.; Cowin, J. P.; Iedema, M. J.; Ali, H.

2010-10-01

Atmospheric particles can be collected in the field on substrates for subsequent laboratory analysis via chemically sensitive single particle methods such as scanning electron microscopy with energy dispersive x-ray analysis. With moving substrates time resolution of seconds to minutes can be achieved. In this paper, we demonstrate how to increase the time resolution when collecting particles on a substrate to a few milliseconds to provide real-time information. Our fast time-resolved aerosol collector ("Fast-TRAC") microscopically observes the particle collection on a substrate and records an on-line video. Particle arrivals are resolved to within a single frame (4-17 ms in this setup), and the spatial locations are matched to the subsequent single particle analysis. This approach also provides in-situ information on particle size and number concentration. Applications are expected in airborne studies of cloud microstructure, pollution plumes, and surface long-term monitoring.

Fast time-resolved aerosol collector: proof of concept

NASA Astrophysics Data System (ADS)

Yu, X.-Y.; Cowin, J. P.; Iedema, M. J.; Ali, H.

2010-06-01

Atmospheric particles can be collected in the field on substrates for subsequent laboratory analysis via chemically sensitive single particle methods such as scanning electron microscopy with energy dispersive x-ray analysis. With moving substrates time resolution of seconds to minutes can be achieved. In this paper, we demonstrate how to increase the time resolution when collecting particles on a substrate to a few milliseconds to provide real-time information. Our fast time-resolved aerosol collector ("Fast-TRAC") microscopically observes the particle collection on a substrate and records an on-line video. Particle arrivals are resolved to within a single frame (4-17 ms in this setup), and the spatial locations are matched to the subsequent single particle analysis. This approach also provides in-situ information on particle size and number concentration. Applications are expected in airborne studies of cloud microstructure, pollution plumes, and surface long-term monitoring.

75 FR 7426 - Periodic Reporting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-19

... change in transportation cost system sampling. The proposal involves distributing rail costs using inter...) sampling, and proposes instead to distribute rail costs using the Inter-BC highway distribution factors. \\1... rail sampling, and to use the TRACS inter-BMC distribtion in place of the Rail distribution key in Cost...

2009 TOXICOLOGY AND RISK ASSESSMENT CONFERENCE

EPA Science Inventory

EPA has announced

The 2009 Toxicology and Risk Assessment Conference
Cincinnati Marriott North, West Chester (Cincinnati), OH
April 27-30, 2009 - Click to register!

The Annual Toxicology and Risk Ass...

Destination Entry And Retrieval With The Ali-Scout Navigation System Fast-Trac Phase Iib Deliverable

DOT National Transportation Integrated Search

1996-12-01

AFTER TRAINING, 36 DRIVERS RETRIEVED AND ENTERED A TOTAL OF 20 DESTINATIONS USING AN ALI-SCOUT NAVIGATION COMPUTER AND 10 DESTINATIONS USING A TOUCHSCREEN SIMULATION WHILE SITTING IN A VEHICLE MOCKUP. RETRIEVAL INVOLVED KEYING IN PART OF THE DESTINAT...

77 FR 59624 - Submission for OMB Review; Comment Request; CareerTrac

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-28

... Reduction Act of 1995, the Fogarty International Center (FIC), National Institute of General Medical Science (NIGMS), National Cancer Institute (NCI), and National Library of Medicine (NLM) of the National Institutes of Health (NIH), in conjunction with the National Institute of Environmental Health Sciences...

78 FR 59758 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-27

... study of tax-exempt bonds (required by Congress). Affected Public: Private sector: Businesses and other... Determination Agreement (for use by employers in the food and beverage industry). Abstract: Information is... for the Food and Beverage Industry (EmTRAC). Abstract: Information is required by the Internal Revenue...

78 FR 24313 - Proposed Collection; Comment Request for Tip Reporting Alternative Commitment Agreement (TRAC...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-24

... DEPARTMENT OF THE TREASURY Internal Revenue Service Proposed Collection; Comment Request for Tip... Industry and The Cosmetology and Barber Industry AGENCY: Internal Revenue Service (IRS), Treasury. ACTION.... ADDRESSES: Direct all written comments to Yvette Lawrence, Internal Revenue Service, room 6129, 1111...

2008 TOXICOLOGY AND RISK ASSESSMENT CONFERENCE

EPA Science Inventory

EPA has announced

The 2008 Toxicology and Risk Assessment Conference
Cincinnati Marriott North, West Chester (Cincinnati), OH
April 14 - 17, 2008 - Click to register!

The Annual Toxicology and Risk ...

77 FR 9893 - Notice of Scope Rulings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-21

... Engineering Limited; its wheel hub units are within the scope of the antidumping duty order; April 18, 2011. A... of China. Requestor: OTR Wheel Engineering, Inc.; its Trac Master and Traction Master tires are... Tissue Paper Products from the People's Republic of China. Requestor: Seaman Paper Company of...

Nuclear Test Personnel Review

Science.gov Websites

History Documents US Underground Nuclear Test History Reports NTPR Radiation Exposure Reports Enewetak Atoll Cleanup Documents TRAC About Who We Are Our Values History Locations Our Leadership Director NTPR Radiation Dose Assessment Documents U.S. Atmospheric Nuclear Test History Reports U.S. Underground

TRAC Searchable Research Library

DTIC Science & Technology

2016-05-01

network accessible document repository for technical documents and similar document artifacts. We used a model-based approach using the Vector...demonstration and model refinement. 14. SUBJECT TERMS Knowledge Management, Document Repository , Digital Library, Vector Directional Data Model...27 Figure D1. Administrator Repository Upload Page. ................................................................... D-2 Figure D2

2007 TOXICOLOGY AND RISK ASSESSMENT CONFERENCE

EPA Science Inventory

EPA has announced

The 2007 Toxicology and Risk Assessment Conference
Cincinnati Marriott North, West Chester (Cincinnati), OH
April 23- 26, 2007 - Click to register!

The Annual Toxicology and Risk Ass...

Privatization and regulation of transport infrastructure in the 1990s : successes ... and bugs to fix for the next millennium

DOT National Transportation Integrated Search

1999-11-01

The FAST-TRAC (Faster and Safer Travel through Traffic Routing and Advanced Controls) Operational Field Test (OFT) is an Intelligent Transportation Systems (ITS) project being conducted in Southeast Michigan, largely within Oakland County. The projec...

Defense Threat Reduction Agency > Careers > Our Values

Science.gov Websites

Atoll Cleanup Documents TRAC About Who We Are Our Values History Locations Our Leadership Director Justifications & Approvals Careers Who We Are Our Values Strategic Recruiting Programs Professional needs. INTEGRITY Our members exhibit the highest ethical standards. Truth, honesty, and courage are

Assessment of the Adequacy of U.S.-Canadian Infrastructure to Accommodate Trade through Eastern Border Crossings. Appendix 5. Michigan Frontier.

DOT National Transportation Integrated Search

1995-09-01

FAST-TRAC: Twelve Intelligent Transportation Systems (ITS) activities were chosen by the Federal Highway Administration to be the subjects of case studies. The case studies were performed under the ITS Institutional and Legal Issues Program, which wa...

77 FR 55265 - Notice of Meeting of the Transit Rail Advisory Committee for Safety (TRACS)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-07

... Secretary and the Federal Transit Administrator on matters relating to the safety of public transportation... Federal Transit Administration (FTA) on matters relating to the safety of public transportation systems... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Notice of Meeting of the Transit Rail...

Defense Threat Reduction Agency > About > History

Science.gov Websites

History Documents US Underground Nuclear Test History Reports NTPR Radiation Exposure Reports Enewetak Atoll Cleanup Documents TRAC About Who We Are Our Values History Locations Our Leadership Director Your Reporting Day Senior Executive Service Special Programs HISTORY DTRA is the youngest agency in the

NTPR Fact Sheets

Science.gov Websites

History Documents US Underground Nuclear Test History Reports NTPR Radiation Exposure Reports Enewetak Atoll Cleanup Documents TRAC About Who We Are Our Values History Locations Our Leadership Director U.S. Atmospheric Nuclear Test History Reports U.S. Underground Nuclear Test History Reports NTPR

Defense Threat Reduction Agency > Success Stories

Science.gov Websites

History Documents US Underground Nuclear Test History Reports NTPR Radiation Exposure Reports Enewetak Atoll Cleanup Documents TRAC About Who We Are Our Values History Locations Our Leadership Director counter WMD weapons systems, we have a long history of overcoming what others believe impossible

US Underground Nuclear Test History Reports

Science.gov Websites

History Documents US Underground Nuclear Test History Reports NTPR Radiation Exposure Reports Enewetak Atoll Cleanup Documents TRAC About Who We Are Our Values History Locations Our Leadership Director Your Reporting Day Senior Executive Service Special Programs U.S. UNDERGROUND NUCLEAR TEST HISTORY

Adaptive Signal Timing Comparison Between the InSync and QuicTrac Adaptive Signal Systems Installed in Colorado

DOT National Transportation Integrated Search

2012-07-01

The FHWAs Every Day Counts (EDC) initiative identifies adaptive signal control as a tool for local agencies to deploy : innovation. In an effort to achieve the goals of the EDC initiative, the traffic sections of the Colorado Department of : Trans...

75 FR 14161 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-24

.... Proposed Project: Transformation Accountability (TRAC) Reporting System --(OMB No. 0930-0285)--Revision... Receiving Mental Health Services. The name of this data collection effort is revised to the Transformation... 2 Education and Employment 4 3 Crime and Criminal Justice........ 1 1 Perception of Care 15 14...

78 FR 53501 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-29

... Commitment (TRAC) Agreement and Tip Rate Determination Agreement (TRDA) for Use in the Food and Beverage... Charged Tips (Other Than in the Food and Beverage Industry and the Cosmetology and Barber Industry). Form... Employer With Tipped Employees (Other Than in the Food and Beverage Industry and the Gaming Industry). Form...

Immune Biomarkers Predictive for Disease-Free Survival with Adjuvant Sunitinib in High-Risk Locoregional Renal Cell Carcinoma: From Randomized Phase III S-TRAC Study.

PubMed

George, Daniel J; Martini, Jean-François; Staehler, Michael; Motzer, Robert J; Magheli, Ahmed; Escudier, Bernard; Gerletti, Paola; Li, Sherry; Casey, Michelle; Laguerre, Brigitte; Pandha, Hardev S; Pantuck, Allan J; Patel, Anup; Lechuga, Maria J; Ravaud, Alain

2018-04-01

Purpose: Adjuvant sunitinib therapy compared with placebo prolonged disease-free survival (DFS) in patients with locoregional high-risk renal cell carcinoma (RCC) in the S-TRAC trial (ClinicalTrials.gov number NCT00375674). A prospectively designed exploratory analysis of tissue biomarkers was conducted to identify predictors of treatment benefit. Experimental Design: Tissue blocks were used for immunohistochemistry (IHC) staining of programmed cell death ligand 1 (PD-L1), CD4, CD8, and CD68. DFS was compared between < versus ≥ median IHC parameter using the Kaplan-Meier method. For biomarkers with predictive potential, receiver operating characteristics curves were generated. Results: Baseline characteristics were similar in patients with ( n = 191) and without ( n = 419) IHC analysis. Among patients with IHC, longer DFS was observed in patients with tumor CD8 + T-cell density ≥ versus < median [median (95% CI), not reached (6.83-not reached) versus 3.47 years (1.73-not reached); hazard ratio (HR) 0.40 (95% CI, 0.20-0.81); P = 0.009] treated with sunitinib ( n = 101), but not with placebo ( n = 90). The sensitivity and specificity for CD8 + T-cell density in predicting DFS were 0.604 and 0.658, respectively. Shorter DFS was observed in placebo-treated patients with PD-L1 + versus PD-L1 - tumors (HR 1.75; P = 0.103). Among all patients with PD-L1 + tumors, DFS was numerically longer with sunitinib versus placebo (HR 0.58; P = 0.175). Conclusions: Greater CD8 + T-cell density in tumor tissue was associated with longer DFS with sunitinib but not placebo, suggesting predictive treatment effect utility. Further independent cohort validation studies are warranted. The prognostic value of PD-L1 expression in primary tumors from patients with high-risk nonmetastatic RCC should also be further explored. Clin Cancer Res; 24(7); 1554-61. ©2018 AACR . ©2018 American Association for Cancer Research.

Measurement Space Drill Support

DTIC Science & Technology

2015-08-30

II) H-47 Block II (I) *H-47 Block II (II) AVN FVL Att (I) * AVN FVL Att (II) TRAC- MTRY F2025B Logistic Flow MS Drill Support FY15 Research...does not have to use other AVN /ground assets to cover the area, freeing these assets to perform other missions and potentially enhancing the

Performance related issues in distributed database systems

NASA Technical Reports Server (NTRS)

Mukkamala, Ravi

1991-01-01

The key elements of research performed during the year long effort of this project are: Investigate the effects of heterogeneity in distributed real time systems; Study the requirements to TRAC towards building a heterogeneous database system; Study the effects of performance modeling on distributed database performance; and Experiment with an ORACLE based heterogeneous system.

Implementing a Military Transitions Program. Strategies for Transformative Change

ERIC Educational Resources Information Center

Mikulka, D.; Remy, K.; Smith, C.; Fox, H. L.

2016-01-01

In 2011, Washburn University of Topeka, Kansas was awarded a $19.6 million Round 1 TAACCCT grant through the Department of Labor to provide industry-relevant, hands-on training for high-demand, high-wage careers. The consortium, Technical Retraining to Achieve Credentials (TRAC-7), was led by Washburn University, and included seven Kansas…

GPS-based Microenvironment Tracker (MicroTrac) Model to Estimate Time-Location of Individuals for Air Pollution Exposure Assessments: Model Evaluation in Central North Carolina

EPA Science Inventory

A critical aspect of air pollution exposure assessment is the estimation of the time spent by individuals in various microenvironments (ME). Accounting for the time spent in different ME with different pollutant concentrations can reduce exposure misclassifications, while failure...

Study of a distributed wireless multi-sensory train approach detection and warning system for improving the safety of railroad workers.

DOT National Transportation Integrated Search

2014-07-01

Safety is a key concern for the North American railroad industry, particularly for their employees. However, in one particular area there is an identified urgent need for a novel solution that helps protect them better than the current approach: trac...

NTPR Radiation Exposure Reports

Science.gov Websites

History Documents US Underground Nuclear Test History Reports NTPR Radiation Exposure Reports Enewetak Atoll Cleanup Documents TRAC About Who We Are Our Values History Locations Our Leadership Director Detonations 1945-1962, Vol II: Oceanic Test Series DNA-6041F For the Record - A History of the Nuclear Test

Enabling On-Demand Database Computing with MIT SuperCloud Database Management System

DTIC Science & Technology

2015-09-15

arc.liv.ac.uk/trac/SGE) provides these services and is independent of programming language (C, Fortran, Java , Matlab, etc) or parallel programming...a MySQL database to store DNS records. The DNS records are controlled via a simple web service interface that allows records to be created

Cowboys with Cameras: An Interactive Expedition

ERIC Educational Resources Information Center

Robert, Kenny; Lenz, Adam

2009-01-01

Utilizing the same technologies pioneered by the embedded journalists in Iraq, the University of Central Florida (UCF) teamed up with TracStar, Inc to create a small-scale, satellite-based expedition transmission package to accompany a university film and digital media professor into parts of Utah and the Moab Desert that had a historical…

A versatile strategy for gene trapping and trap conversion in emerging model organisms.

PubMed

Kontarakis, Zacharias; Pavlopoulos, Anastasios; Kiupakis, Alexandros; Konstantinides, Nikolaos; Douris, Vassilis; Averof, Michalis

2011-06-01

Genetic model organisms such as Drosophila, C. elegans and the mouse provide formidable tools for studying mechanisms of development, physiology and behaviour. Established models alone, however, allow us to survey only a tiny fraction of the morphological and functional diversity present in the animal kingdom. Here, we present iTRAC, a versatile gene-trapping approach that combines the implementation of unbiased genetic screens with the generation of sophisticated genetic tools both in established and emerging model organisms. The approach utilises an exon-trapping transposon vector that carries an integrase docking site, allowing the targeted integration of new constructs into trapped loci. We provide proof of principle for iTRAC in the emerging model crustacean Parhyale hawaiensis: we generate traps that allow specific developmental and physiological processes to be visualised in unparalleled detail, we show that trapped genes can be easily cloned from an unsequenced genome, and we demonstrate targeting of new constructs into a trapped locus. Using this approach, gene traps can serve as platforms for generating diverse reporters, drivers for tissue-specific expression, gene knockdown and other genetic tools not yet imagined.

Arterial pressure-based cardiac output monitoring: a multicenter validation of the third-generation software in septic patients.

PubMed

De Backer, Daniel; Marx, Gernot; Tan, Andrew; Junker, Christopher; Van Nuffelen, Marc; Hüter, Lars; Ching, Willy; Michard, Frédéric; Vincent, Jean-Louis

2011-02-01

Second-generation FloTrac software has been shown to reliably measure cardiac output (CO) in cardiac surgical patients. However, concerns have been raised regarding its accuracy in vasoplegic states. The aim of the present multicenter study was to investigate the accuracy of the third-generation software in patients with sepsis, particularly when total systemic vascular resistance (TSVR) is low. Fifty-eight septic patients were included in this prospective observational study in four university-affiliated ICUs. Reference CO was measured by bolus pulmonary thermodilution (iCO) using 3-5 cold saline boluses. Simultaneously, CO was computed from the arterial pressure curve recorded on a computer using the second-generation (CO(G2)) and third-generation (CO(G3)) FloTrac software. CO was also measured by semi-continuous pulmonary thermodilution (CCO). A total of 401 simultaneous measurements of iCO, CO(G2), CO(G3), and CCO were recorded. The mean (95%CI) biases between CO(G2) and iCO, CO(G3) and iCO, and CCO and iCO were -10 (-15 to -5)% [-0.8 (-1.1 to -0.4) L/min], 0 (-4 to 4)% [0 (-0.3 to 0.3) L/min], and 9 (6-13)% [0.7 (0.5-1.0) L/min], respectively. The percentage errors were 29 (20-37)% for CO(G2), 30 (24-37)% for CO(G3), and 28 (22-34)% for CCO. The difference between iCO and CO(G2) was significantly correlated with TSVR (r(2) = 0.37, p < 0.0001). A very weak (r(2) = 0.05) relationship was also observed for the difference between iCO and CO(G3). In patients with sepsis, the third-generation FloTrac software is more accurate, as precise, and less influenced by TSVR than the second-generation software.

Application of Impedance Microbiology for Evaluating Potential Acidifying Performances of Starter Lactic Acid Bacteria to Employ in Milk Transformation.

PubMed

Bancalari, Elena; Bernini, Valentina; Bottari, Benedetta; Neviani, Erasmo; Gatti, Monica

2016-01-01

Impedance microbiology is a method that enables tracing microbial growth by measuring the change in the electrical conductivity. Different systems, able to perform this measurement, are available in commerce and are commonly used for food control analysis by mean of measuring a point of the impedance curve, defined "time of detection." With this work we wanted to find an objective way to interpret the metabolic significance of impedance curves and propose it as a valid approach to evaluate the potential acidifying performances of starter lactic acid bacteria to be employed in milk transformation. To do this it was firstly investigated the possibility to use the Gompertz equation to describe the data coming from the impedance curve obtained by mean of BacTrac 4300®. Lag time (λ), maximum specific M% rate (μmax), and maximum value of M% (Yend) have been calculated and, given the similarity of the impedance fitted curve to the bacterial growth curve, their meaning has been interpreted. Potential acidifying performances of eighty strains belonging to Lactobacillus helveticus, Lactobacillus delbrueckii subsp. bulgaricus, Lactococcus lactis , and Streptococcus thermophilus species have been evaluated by using the kinetics parameters, obtained from Excel add-in DMFit version 2.1. The novelty and importance of our findings, obtained by means of BacTrac 4300®, is that they can also be applied to data obtained from other devices. Moreover, the meaning of λ, μmax, and Yend that we have extrapolated from Modified Gompertz equation and discussed for lactic acid bacteria in milk, can be exploited also to other food environment or other bacteria, assuming that they can give a curve and that curve is properly fitted with Gompertz equation.

Application of Impedance Microbiology for Evaluating Potential Acidifying Performances of Starter Lactic Acid Bacteria to Employ in Milk Transformation

PubMed Central

Bancalari, Elena; Bernini, Valentina; Bottari, Benedetta; Neviani, Erasmo; Gatti, Monica

2016-01-01

Impedance microbiology is a method that enables tracing microbial growth by measuring the change in the electrical conductivity. Different systems, able to perform this measurement, are available in commerce and are commonly used for food control analysis by mean of measuring a point of the impedance curve, defined “time of detection.” With this work we wanted to find an objective way to interpret the metabolic significance of impedance curves and propose it as a valid approach to evaluate the potential acidifying performances of starter lactic acid bacteria to be employed in milk transformation. To do this it was firstly investigated the possibility to use the Gompertz equation to describe the data coming from the impedance curve obtained by mean of BacTrac 4300®. Lag time (λ), maximum specific M% rate (μmax), and maximum value of M% (Yend) have been calculated and, given the similarity of the impedance fitted curve to the bacterial growth curve, their meaning has been interpreted. Potential acidifying performances of eighty strains belonging to Lactobacillus helveticus, Lactobacillus delbrueckii subsp. bulgaricus, Lactococcus lactis, and Streptococcus thermophilus species have been evaluated by using the kinetics parameters, obtained from Excel add-in DMFit version 2.1. The novelty and importance of our findings, obtained by means of BacTrac 4300®, is that they can also be applied to data obtained from other devices. Moreover, the meaning of λ, μmax, and Yend that we have extrapolated from Modified Gompertz equation and discussed for lactic acid bacteria in milk, can be exploited also to other food environment or other bacteria, assuming that they can give a curve and that curve is properly fitted with Gompertz equation. PMID:27799925

Plant canopy gap-size analysis theory for improving optical measurements of leaf-area index

NASA Astrophysics Data System (ADS)

Chen, Jing M.; Cihlar, Josef

1995-09-01

Optical instruments currently available for measuring the leaf-area index (LAI) of a plant canopy all utilize only the canopy gap-fraction information. These instruments include the Li-Cor LAI-2000 Plant Canopy Analyzer, Decagon, and Demon. The advantages of utilizing both the canopy gap-fraction and gap-size information are shown. For the purpose of measuring the canopy gap size, a prototype sunfleck-LAI instrument named Tracing Radiation and Architecture of Canopies (TRAC), has been developed and tested in two pure conifer plantations, red pine (Pinus resinosa Ait.) and jack pine (Pinus banksiana Lamb). A new gap-size-analysis theory is presented to quantify the effect of canopy architecture on optical measurements of LAI based on the gap-fraction principle. The theory is an improvement on that of Lang and Xiang [Agric. For. Meteorol. 37, 229 (1986)]. In principle, this theory can be used for any heterogeneous canopies.

Optimizing dual-energy x-ray parameters for the ExacTrac clinical stereoscopic imaging system to enhance soft-tissue imaging.

PubMed

Bowman, Wesley A; Robar, James L; Sattarivand, Mike

2017-03-01

Stereoscopic x-ray image guided radiotherapy for lung tumors is often hindered by bone overlap and limited soft-tissue contrast. This study aims to evaluate the feasibility of dual-energy imaging techniques and to optimize parameters of the ExacTrac stereoscopic imaging system to enhance soft-tissue imaging for application to lung stereotactic body radiation therapy. Simulated spectra and a physical lung phantom were used to optimize filter material, thickness, tube potentials, and weighting factors to obtain bone subtracted dual-energy images. Spektr simulations were used to identify material in the atomic number range (3-83) based on a metric defined to separate spectra of high and low-energies. Both energies used the same filter due to time constraints of imaging in the presence of respiratory motion. The lung phantom contained bone, soft tissue, and tumor mimicking materials, and it was imaged with a filter thickness in the range of (0-0.7) mm and a kVp range of (60-80) for low energy and (120,140) for high energy. Optimal dual-energy weighting factors were obtained when the bone to soft-tissue contrast-to-noise ratio (CNR) was minimized. Optimal filter thickness and tube potential were achieved by maximizing tumor-to-background CNR. Using the optimized parameters, dual-energy images of an anthropomorphic Rando phantom with a spherical tumor mimicking material inserted in his lung were acquired and evaluated for bone subtraction and tumor contrast. Imaging dose was measured using the dual-energy technique with and without beam filtration and matched to that of a clinical conventional single energy technique. Tin was the material of choice for beam filtering providing the best energy separation, non-toxicity, and non-reactiveness. The best soft-tissue-weighted image in the lung phantom was obtained using 0.2 mm tin and (140, 60) kVp pair. Dual-energy images of the Rando phantom with the tin filter had noticeable improvement in bone elimination, tumor contrast, and noise content when compared to dual-energy imaging with no filtration. The surface dose was 0.52 mGy per each stereoscopic view for both clinical single energy technique and the dual-energy technique in both cases of with and without the tin filter. Dual-energy soft-tissue imaging is feasible without additional imaging dose using the ExacTrac stereoscopic imaging system with optimized acquisition parameters and no beam filtration. Addition of a single tin filter for both the high and low energies has noticeable improvements on dual-energy imaging with optimized parameters. Clinical implementation of a dual-energy technique on ExacTrac stereoscopic imaging could improve lung tumor visibility. © 2017 American Association of Physicists in Medicine.

SU-E-T-659: Quantitative Evaluation of Patient Setup Accuracy of Stereotactic Radiotherapy with the Frameless 6D-ExacTrac System Using Statistical Modeling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keeling, V; Jin, H; Hossain, S

2015-06-15

Purpose: To evaluate patient setup accuracy and quantify individual and cumulative positioning uncertainties associated with different hardware and software components of the stereotactic radiotherapy (SRS/SRT) with the frameless-6D-ExacTrac system. Methods: A statistical model was used to evaluate positioning uncertainties of the different components of SRS/SRT treatment with the BrainLAB 6D-ExacTrac system using the positioning shifts of 35 patients having cranial lesions (49 total lesions treated in 1, 3, 5 fractions). All these patients were immobilized with rigid head-and-neck masks, simulated with BrainLAB-localizer and planned with iPlan treatment planning system. Infrared imaging (IR) was used initially to setup patients. Then, stereoscopicmore » x-ray images (XC) were acquired and registered to corresponding digitally-reconstructed-radiographs using bony-anatomy matching to calculate 6D-translational and rotational shifts. When the shifts were within tolerance (0.7mm and 1°), treatment was initiated. Otherwise corrections were applied and additional x-rays were acquired (XV) to verify that patient position was within tolerance. Results: The uncertainties from the mask, localizer, IR-frame, x-ray imaging, MV and kV isocentricity were quantified individually. Mask uncertainty (Translational: Lateral, Longitudinal, Vertical; Rotational: Pitch, Roll, Yaw) was the largest and varied with patients in the range (−1.05−1.50mm, −5.06–3.57mm, −5.51−3.49mm; −1.40−2.40°, −1.24−1.74°, and −2.43−1.90°) obtained from mean of XC shifts for each patient. Setup uncertainty in IR positioning (0.88,2.12,1.40mm, and 0.64,0.83,0.96°) was extracted from standard-deviation of XC. Systematic uncertainties of the localizer (−0.03,−0.01,0.03mm, and −0.03,0.00,−0.01°) and frame (0.18,0.25,−1.27mm,−0.32,0.18, and 0.47°) were extracted from means of all XV setups and mean of all XC distributions, respectively. Uncertainties in isocentricity of the MV radiotherapy machine were (0.27,0.24,0.34mm) and kV-imager (0.15,−0.4,0.21mm). Conclusion: A statistical model was developed to evaluate the individual and cumulative systematic and random uncertainties induced by the different hardware and software components of the 6D-ExacTrac-system. The immobilization mask was associated with the largest positioning uncertainty.« less

Data Mining and Visualization of Twin-Cities Traffic Data

DTIC Science & Technology

2001-03-08

Ramsey I W Q Ramsey Table The...using the n attributes in the data set The class models are then used to classify test set which the class labels are not provided A decisiontree...interval for January while the testing set is the trac ow on January The training accuracy is and testing accuracy is The

78 FR 19367 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-29

....dfo-mpo.gc.ca/science/trac/tsr.html . The TMGC met in September 2012 to recommend shared TACs for FY... benchmark assessment is available from the Northeast Fisheries Science Center at: http://www.nefsc.noaa.gov... better understanding of the nature and extent of the scientific uncertainty. As a result, the SSC...

Incident management under SCAT adaptive control system : FAST-TRAC phase III deliverable. #11, Final report on incident management under SCATS adaptive control system

DOT National Transportation Integrated Search

1998-04-01

The report documents the results of a study designed to test the effectiveness of ATMS and ATIS strategies to reduce delay resulting from an incident. The study had two main sections: a simulation study to test the effectiveness of several control st...

A second anniversary operational review of the OmniTRACS(R): The first two-way mobile Ku-band satellite communications system

NASA Technical Reports Server (NTRS)

Jacobs, Irwin M.; Salmasi, Allen; Gilhousen, Klein S.; Weaver, Lindsay A., Jr.; Bernard, Thomas J.

1990-01-01

A novel two-way mobile satellite communications and vehicle position reporting system that is currently operational in the United States and Europe is described. The system characteristics and service operations are described in detail. Technical descriptions of the equipment and signal processing techniques are provided.

Clustering of two genes putatively involved in cyanate detoxification evolved recently and independently in multiple fungal lineages

USDA-ARS?s Scientific Manuscript database

Fungi that have the enzymes cyanase and carbonic anhydrase show a limited capacity to detoxify cyanate, a fungicide employed by both plants and humans. Here, we describe a novel two-gene cluster that comprises duplicated cyanase and carbonic anhydrase copies, which we name the CCA gene cluster, trac...

Spatial-temporal interactions of beef cattle and wolves on a western Idaho rangeland

USDA-ARS?s Scientific Manuscript database

The objective of this experiment was to detect and evaluate interactions between free-roaming beef cattle (Bos taurus) and wolves (Canis lupus) using GPS technology. Ten mature, lactating beef cows from a herd of about 450 cow-calf pairs and 1 wolf from a pack of 13 wolves were GPS collared and trac...

76 FR 20054 - Self-Regulatory Organizations; the NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-11

... over 50,000,000 investors on Web sites operated by Google, Interactive Data, and Dow Jones, among... systems (``ATSs''), including dark pools and electronic communication networks (``ECNs''). Each SRO market..., Attain, TracECN, BATS Trading and Direct Edge. Today, BATS publishes its data at no charge on its Web...

PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data

PubMed Central

Zhang, Yanju; Lameijer, Eric-Wubbo; 't Hoen, Peter A. C.; Ning, Zemin; Slagboom, P. Eline; Ye, Kai

2012-01-01

Motivation: RNA-seq is a powerful technology for the study of transcriptome profiles that uses deep-sequencing technologies. Moreover, it may be used for cellular phenotyping and help establishing the etiology of diseases characterized by abnormal splicing patterns. In RNA-Seq, the exact nature of splicing events is buried in the reads that span exon–exon boundaries. The accurate and efficient mapping of these reads to the reference genome is a major challenge. Results: We developed PASSion, a pattern growth algorithm-based pipeline for splice site detection in paired-end RNA-Seq reads. Comparing the performance of PASSion to three existing RNA-Seq analysis pipelines, TopHat, MapSplice and HMMSplicer, revealed that PASSion is competitive with these packages. Moreover, the performance of PASSion is not affected by read length and coverage. It performs better than the other three approaches when detecting junctions in highly abundant transcripts. PASSion has the ability to detect junctions that do not have known splicing motifs, which cannot be found by the other tools. Of the two public RNA-Seq datasets, PASSion predicted ∼ 137 000 and 173 000 splicing events, of which on average 82 are known junctions annotated in the Ensembl transcript database and 18% are novel. In addition, our package can discover differential and shared splicing patterns among multiple samples. Availability: The code and utilities can be freely downloaded from https://trac.nbic.nl/passion and ftp://ftp.sanger.ac.uk/pub/zn1/passion Contact: y.zhang@lumc.nl; k.ye@lumc.nl Supplementary information: Supplementary data are available at Bioinformatics online. PMID:22219203

Sleep abnormalities in children with Dravet syndrome.

PubMed

Dhamija, Radhika; Erickson, Maia K; St Louis, Erik K; Wirrell, Elaine; Kotagal, Suresh

2014-05-01

Mutations in the voltage-gated sodium channel SCN1A gene are responsible for the majority of Dravet syndrome cases. There is evidence that the Nav1.1 channel coded by the SCN1A gene is involved in sleep regulation. We evaluated sleep abnormalities in children with Dravet syndrome using nocturnal polysomnography. We identified six children at our institution with genetically confirmed Dravet syndrome who had also undergone formal sleep consultation with nocturnal polysomnography. Indications for polysomnography were parental concern of daytime fatigue or sleepiness, hyperactivity, inattention, disruptive behavior, nighttime awakenings, or nocturnal seizures. Sleep studies were scored according to guidelines of the American Academy of Sleep Medicine and non-rapid eye movement cyclic alternating pattern was visually identified and scored according to established methods. The mean age of the subjects at the time of polysomnography was 6 years. Standard polysomnography did not show any consistent abnormalities in the obstructive or central apnea index, arousal index, sleep efficiency, or architecture. Cyclic alternating pattern analysis on five patients showed an increased mean rate of 50.3% (vs 31% to 34% in neurological normal children) with a mild increase in A1 subtype of 89.4% (vs 84.5%). A2/A3 subtype (5.3% vs 7.3%) and B phase duration (22.4 vs 24.7 seconds) were similar to previously reported findings in neurologically normal children. Despite parental concerns for sleep disturbance in patients with Dravet syndrome, we could not identify abnormalities in sleep macroarchitecture. Non-rapid eye movement sleep microarchitecture was, however, abnormal, with increased A1 subtype, somewhat resembling a tracé alternant pattern of neonates and possibly suggestive of cortical synaptic immaturity in Dravet syndrome. Larger studies are needed to replicate these results. Copyright © 2014 Elsevier Inc. All rights reserved.

TRAC Innovation Report (FY15 to FY18)

DTIC Science & Technology

2017-11-01

PAGE INTENTIONALLY LEFT BLANK REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden for this collection of information ...maintaining the data needed, and completing and reviewing the collection of information . Send comments regarding this burden estimate or any other aspect of...this collection of information , including suggestions for reducing this burden, to Washington headquarters Services, Directorate for Information

76 FR 64147 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-17

..., there is no economic basis for regulating maximum prices for one of the joint products in an industry in... proprietary book data on the Internet. Second, because a single order or transaction report can appear in an... Tradebook, Island, RediBook, Attain, TracECN, BATS Trading and Direct Edge. A proliferation of dark pools...

78 FR 3346 - Fisheries of the Northeastern United States; Atlantic Mackerel, Squid, and Butterfish Fisheries...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-16

... information is available. The mackerel stock-wide ABC was set at 80,000 mt for 2012, consistent with the TRAC... maintaining the 2012 mackerel specification and specifying the stock-wide ABC for 3 years (2013-2015) at 80... the world market, in direct competition with U.S. industry efforts to expand exports. While a surplus...

Transportation research : the Department of Transportation has made progress in coordinating and reviewing its research activities : testimony before the Subcommittee on Technology and Innovation, Committee on Science and Technology, House of Representatives

DOT National Transportation Integrated Search

2009-02-12

The FAST-TRAC (Faster and Safer Travel through Traffic Routing and Advanced Controls) Operational Field Test (OFT) is an Intelligent Transportation Systems (ITS) project being conducted in Southeast Michigan, managed by the Road Commission of Oakland...

Estimating Energy Expenditure with the RT3 Triaxial Accelerometer

ERIC Educational Resources Information Center

Maddison, Ralph; Jiang, Yannan; Vander Hoorn, Stephen; Mhurchu, Cliona Ni; Lawes, Carlene M. M.; Rodgers, Anthony; Rush, Elaine

2009-01-01

The RT3 is a relatively new triaxial accelerometer that has replaced the TriTrac. The aim of this study was to validate the RT3 against doubly labeled water (DLW) in a free-living, mixed weight sample of adults. Total energy expenditure (TEE) was measured over a 15-day period using DLW. Activity-related energy expenditure (AEE) was estimated by…

In situ treatability testing of reductive dechlorination in wetland sediments

USGS Publications Warehouse

Lorah, M.M.; Majcher, E.; Jones, E.; Driedger, G.; Dworatzek, S.; Graves, D.

2005-01-01

In situ treatability testing was conducted in the discharge wetlands along West Branch Canal Creek at Aberdeen Proving Ground, MD. The potential for stimulating reductive dechlorination of 1,1,2,2-tetrachloroethane, tetrachloroethylene, trichloroethylene, and carbon tetrachloride in areas of preferential discharge or seeps was evaluated. Geological Survey that degrades chlorinated ethanes and ethylenes was tested using MICRO-Trac??? devices. At seep 3-4W, results of the C and BA MICRO-Trac??? treatments showed essentially no biodegradation of chlorinated solvents occurring under natural and bioaugmented conditions. Results of geochemical samples at this site indicated predominantly iron- and sulfate-reducing conditions consistent with the rapid discharge rates previously measured. The biostimulated treatment showed stimulation of methanogenic conditions and partial degradation of the parent chlorinated VOC to intermediate chlorinated compounds. The bioaugmented and bistimulated treatment showed the highest production of methane, the highest removal of parent compounds and intermediate daughter products, and the highest production of the non-chlorinated end product ethylene. This is an abstract of a paper presented at the proceedings of the 8th International In Situ and On-Site Bioremediation Symposium (Baltimore, MD 6/6-9/2005).

Neutron radiography experiments for verification of soluble boron mixing and transport modeling under natural circulation conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feltus, M.A.; Morlang, G.M.

1996-06-01

The use of neutron radiography for visualization of fluid flow through flow visualization modules has been very successful. Current experiments at the Penn State Breazeale Reactor serve to verify the mixing and transport of soluble boron under natural flow conditions as would be experienced in a pressurized water reactor. Different flow geometries have been modeled including holes, slots, and baffles. Flow modules are constructed of aluminum box material 1 1/2 inches by 4 inches in varying lengths. An experimental flow system was built which pumps fluid to a head tank and natural circulation flow occurs from the head tank throughmore » the flow visualization module to be radiographed. The entire flow system is mounted on a portable assembly to allow placement of the flow visualization module in front of the neutron beam port. A neutron-transparent fluorinert fluid is used to simulate water at different densities. Boron is modeled by gadolinium oxide powder as a tracer element, which is placed in a mixing assembly and injected into the system by remote operated electric valve, once the reactor is at power. The entire sequence is recorded on real-time video. Still photographs are made frame-by-frame from the video tape. Computers are used to digitally enhance the video and still photographs. The data obtained from the enhancement will be used for verification of simple geometry predictions using the TRAC and RELAP thermal-hydraulic codes. A detailed model of a reactor vessel inlet plenum, downcomer region, flow distribution area and core inlet is being constructed to model the AP600 plenum. Successive radiography experiments of each section of the model under identical conditions will provide a complete vessel/core model for comparison with the thermal-hydraulic codes.« less

Multiloop integral system test (MIST): Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gloudemans, J.R.

1991-04-01

The Multiloop Integral System Test (MIST) is part of a multiphase program started in 1983 to address small-break loss-of-coolant accidents (SBLOCAs) specific to Babcock and Wilcox designed plants. MIST is sponsored by the US Nuclear Regulatory Commission, the Babcock Wilcox Owners Group, the Electric Power Research Institute, and Babcock and Wilcox. The unique features of the Babcock and Wilcox design, specifically the hot leg U-bends and steam generators, prevented the use of existing integral system data or existing integral facilities to address the thermal-hydraulic SBLOCA questions. MIST was specifically designed and constructed for this program, and an existing facility --more » the Once Through Integral System (OTIS) -- was also used. Data from MIST and OTIS are used to benchmark the adequacy of system codes, such as RELAP5 and TRAC, for predicting abnormal plant transients. The MIST program is reported in 11 volumes. Volumes 2 through 8 pertain to groups of Phase 3 tests by type; Volume 9 presents inter-group comparisons; Volume 10 provides comparisons between the RELAP5/MOD2 calculations and MIST observations, and Volume 11 (with addendum) presents the later Phase 4 tests. This is Volume 1 of the MIST final report, a summary of the entire MIST program. Major topics include, Test Advisory Group (TAG) issues, facility scaling and design, test matrix, observations, comparison of RELAP5 calculations to MIST observations, and MIST versus the TAG issues. MIST generated consistent integral-system data covering a wide range of transient interactions. MIST provided insight into integral system behavior and assisted the code effort. The MIST observations addressed each of the TAG issues. 11 refs., 29 figs., 9 tabs.« less

Novel use of a Dektak 150 surface profiler unmasks differences in resorption pit profiles between control and Charcot patient osteoclasts.

PubMed

Petrova, Nina L; Petrov, Peter K; Edmonds, Michael E; Shanahan, Catherine M

2014-04-01

We hypothesized that newly formed osteoclasts from patients with acute Charcot osteoarthropathy can resorb surfaces of bone more extensively compared with controls. Peripheral blood monocytes, isolated from eight Charcot patients and nine controls, were cultured in vitro on 24-well plates and bovine bone discs in duplicate with macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor κβ ligand (RANKL). Osteoclast formation was assessed by tartrate-resistant acid phosphatase staining (TRAcP) at day 17. Resorption was measured at day 21 after toluidine blue staining by two methods: (1) area of resorption at the surface by image analysis (%) and (2) area of resorption under the surface (μm(2)) measured by a Dektak 150 Surface Profiler. Ten 1,000 μm-long scans were performed per disc. Pits were classified as unidented, bidented, and multidented according to their shape. Although the number of newly formed TRAcP positive multinucleated cells (>3 nuclei) was similar in M-CSF + RANKL-treated cultures between controls and Charcot patients, the latter exhibited increased resorbing activity. The area of resorption on the surface by image analysis was significantly greater in Charcot patients compared with controls (21.1 % [14.5-26.2] vs. 40.8 % [35.4-46.0], median [25-75th percentile], p < 0.01), as was the area of resorption under the surface (2.7 x 10(3) μm(2) [1.6 x 10(3)- 3.9 x 10(3)] vs. 8.3 x 10(3) μm (2) [5.6 x 10(3)- 10.6 x 10(3), [corrected] p < 0.01) after profilometry. In Charcot patients pits were deeper and wider and more frequently presented as multidented pits. This application of the Dektak 150 Surface Profiler revealed novel differences in resorption pit profile from osteoclasts derived from Charcot patients compared with controls. Resorption in Charcot patients was mediated by highly aggressive newly formed osteoclasts from monocytes eroding large and deep areas of bone.

Cloud Condensation Nuclei in Cumulus Humilis - Selected Case Study During the CHAPS Campaign

NASA Astrophysics Data System (ADS)

Yu, X.; Berg, L. K.; Berkowitz, C. M.; Alexander, M. L.; Lee, Y.; Laskin, A.; Ogren, J. A.; Andrews, B.

2009-12-01

The Cumulus Humilis Aerosol Processing Study (CHAPS) provided a unique opportunity to study aerosol and cloud processing. Clouds play an active role in the processing and cycling of atmospheric constituents. Gases and particles can partition to cloud droplets by absorption and condensation as well as activation and pact scavenging. The Department of Energy (DOE) G-1 aircraft was used as one of the main platforms in CHAPS. Flight tracks were designed and implemented to characterize freshly emitted aerosols on cloud top and cloud base as well as with cloud, i.e., cumulus humilis (or fair-weather cumulus), in the vicinity of Oklahoma City. Measurements of interstitial aerosols and residuals of activated condensation cloud nuclei were conducted simultaneously. The interstitial aerosols were determined downstream of an isokinetic inlet; and the activated particles downstream of a counter-flow virtual impactor (CVI). The sampling line to the Aerodyne Aerosol Mass Spectrometer was switched between the isokinetic inlet and the CVI to allow characterization of interstitial particles out of clouds in contrast to particles activated in clouds. Trace gases including ozone, carbon monoxide, sulfur dioxide, and a series of volatile organic compounds (VOCs) were also measured as were key meteorological state parameters including liquid water content, cloud drop size, and dew point temperature were measured. This work will focus on studying CCN properties in cumulus humilis. Several approaches will be taken. The first is single particle analysis of particles collected by the Time-Resolved Aerosol Sampler (TRAC) by SEM/TEM coupled with EDX. We will specifically look into differences in particle properties such as chemical composition and morphology between activated and interstitial ones. The second analysis will link in situ measurements with the snap shots observations by TRAC. For instance, by looking into the characteristic m/z obtained by AMS vs. CO or isoprene, one can gain more insight into the role of primary and secondary organic aerosols in CCNs and background aerosols. Combined with observations of cloud properties, an improved picture of CCN activation in cumulus humilis can be made.

Public Television Viewing in a Dual Channel Market: Some Big Surprises! Info. Packets No. 13.

ERIC Educational Resources Information Center

LeRoy, David; LeRoy, Judith

In a recent study of the Tampa (Florida) market, TRAC Media Services acquired some interesting information about the market's response to its two public television stations. WEDU is a VHF-signal community station that reaches about 745,000 households in a week, and WUSF is a university-licensed UHF station that reaches about 547,000. Month-long…

SU-E-P-41: Imaging Coordination of Cone Beam CT, On-Board Image Conjunction with Optical Image Guidance for SBRT Treatment with Respiratory Motion Management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Y; Campbell, J

2015-06-15

Purpose: To spare normal tissue for SBRT lung/liver patients, especially for patients with significant tumor motion, image guided respiratory motion management has been widely implemented in clinical practice. The purpose of this study was to evaluate imaging coordination of cone beam CT, on-board X-ray image conjunction with optical image guidance for SBRT treatment with motion management. Methods: Currently in our clinic a Varian Novlis Tx was utilized for treating SBRT patients implementing CBCT. A BrainLAB X-ray ExacTrac imaging system in conjunction with optical guidance was primarily used for SRS patients. CBCT and X-ray imaging system were independently calibrated with 1.0more » mm tolerance. For SBRT lung/liver patients, the magnitude of tumor motion was measured based-on 4DCT and the measurement was analyzed to determine if patients would be beneficial with respiratory motion management. For patients eligible for motion management, an additional CT with breath holding would be scanned and used as primary planning CT and as reference images for Cone beam CT. During the SBRT treatment, a CBCT with pause and continuing technology would be performed with patients holding breath, which may require 3–4 partially scanned CBCT to combine as a whole CBCT depending on how long patients capable of holding breath. After patients being setup by CBCT images, the ExactTrac X-ray imaging system was implemented with patients’ on-board X-ray images compared to breath holding CT-based DRR. Results: For breath holding patients SBRT treatment, after initially localizing patients with CBCT, we then position patients with ExacTrac X-ray and optical imaging system. The observed deviations of real-time optical guided position average at 3.0, 2.5 and 1.5 mm in longitudinal, vertical and lateral respectively based on 35 treatments. Conclusion: The respiratory motion management clinical practice improved our physician confidence level to give tighter tumor margin for sparing normal tissue for SBRT lung/liver patients.« less

SU-E-T-300: Spatial Variations of Multiple Off-Axial Targets for a Single Isocenter SRS Treatment Plan in ExacTrac 6D Robotic Couch System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, S; Tseng, T

2014-06-01

Purpose: To evaluate the spatial variations of multiple off-axial targets for a single isocenter stereotactic radiosurgery (SRS) treatment plan in ExacTrac 6D robotic couch system (BrainLab AG). Methods: Five metallic ball bearing (BB) markers were placed sparsely in 3D off-axial locations (non-coplanar) inside a skull phantom as the representatives of multiple targets mimicking multiple brain metastases. The locations of the BB markers were carefully chosen to minimize overlapping of each other in a port imaging detector plane. The skull phantom was immobilized by a frameless mask and CT scanned with a BrainLab Head and Neck Localizer using a GE Optimamore » MDCT scanner. The CT images were exported to iPlan software (BrainLab AG) and a multiple target PTV was drawn by combining all the contours of the BBs. The margin of the MLC opening was selected as 3 mm expansion outward. Two coplanar arc beams were placed to generate a single isocenter SRS plan to treat the PTV. The arc beams were delivered using Novalis Tx system with portal imaging acquisition mode per 10% temporal resolution. The locations of the BBs were visualized and analyzed with respect to the MLC aperture in the treatment plan similar to the Winston-Lutz test. Results: All the BBs were clearly identified inside the MLC openings. The positional errors for the BBs were overall less than 1 mm along the rotational path of the two arcs. Conclusion: This study verified that the spatial deviations of multiple off-axial targets for a single isocenter SRS treatment plan is within sub-millimeter range in ExacTrac 6D robotic couch system. Accompanied with the Winston-Lutz test, this test will quality-assure the spatial accuracies of the isocenter as well as the positions of multiple off-axial targets for the SRS treatment using a single isocenter multiple target treatment plan.« less

TRAC analyses for CCTF and SCTF tests and UPTF design/operation. [Cylindrical Core Test Facility; Slab Core Test Facility; Upper Plenum Test Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spore, J.W.; Cappiello, M.W.; Dotson, P.J.

The analytical support in 1985 for Cylindrical Core Test Facility (CCTF), Slab Core Test Facility (SCTF), and Upper Plenum Test Facility (UPTF) tests involves the posttest analysis of 16 tests that have already been run in the CCTF and the SCTF and the pretest analysis of 3 tests to be performed in the UPTF. Posttest analysis is used to provide insight into the detailed thermal-hydraulic phenomena occurring during the refill and reflood tests performed in CCTF and SCTF. Pretest analysis is used to ensure that the test facility is operated in a manner consistent with the expected behavior of anmore » operating full-scale plant during an accident. To obtain expected behavior of a plant during an accident, two plant loss-of-coolant-accident (LOCA) calculations were performed: a 200% cold-leg-break LOCA calculation for a 2772 MW(t) Babcock and Wilcox plant and a 200% cold-leg-break LOCA calculation for a 3315 MW(t) Westinghouse plant. Detailed results are presented for several CCTF UPI tests and the Westinghouse plant analysis.« less

Vision Trainer Teaches Focusing Techniques at Home

NASA Technical Reports Server (NTRS)

2015-01-01

Based on work Stanford Research Institute did for Ames Research Center, Joseph Trachtman developed a vision trainer to treat visual focusing problems in the 1980s. In 2014, Trachtman, operating out of Seattle, released a home version of the device called the Zone-Trac. The inventor has found the biofeedback process used by the technology induces an alpha-wave brain state, causing increased hand-eye coordination and reaction times, among other effects

Radio frequency tags systems to initiate system processing

NASA Astrophysics Data System (ADS)

Madsen, Harold O.; Madsen, David W.

1994-09-01

This paper describes the automatic identification technology which has been installed at Applied Magnetic Corp. MR fab. World class manufacturing requires technology exploitation. This system combines (1) FluoroTrac cassette and operator tracking, (2) CELLworks cell controller software tools, and (3) Auto-Soft Inc. software integration services. The combined system eliminates operator keystrokes and errors during normal processing within a semiconductor fab. The methods and benefits of this system are described.

Robust Multi Sensor Classification via Jointly Sparse Representation

DTIC Science & Technology

2016-03-14

rank, sensor network, dictionary learning REPORT DOCUMENTATION PAGE 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 10. SPONSOR/MONITOR’S ACRONYM(S) ARO 8...with ultrafast laser pulses, Optics Express, (04 2015): 10521. doi: Xiaoxia Sun, Nasser M. Nasrabadi, Trac D. Tran. Task-Driven Dictionary Learning...in dictionary design, compressed sensors design, and optimization in sparse recovery also helps. We are able to advance the state of the art

Scalable, Flexible and Active Learning on Distributions

DTIC Science & Technology

2016-09-01

enthusiasm about widely varying research ideas was inspiring. Junier Oliva always knew the right way to think about something when I got stuck. Tzu -Kuo...109 Bibliography 113 iii iv Chapter 1 Introduction Traditional machine learning approaches focus on learning problems defined on...with Tzu -Kuo (TK) Huang. 2 et al. 2012; Ntampaka, Trac, Sutherland, Battaglia, et al. 2015; Jin 2016; Jin et al. 2016; Sutherland, J. B. Oliva, et al

Two way assessment of other physical work demands while measuring the whole body vibration magnitude

NASA Astrophysics Data System (ADS)

Tiemessen, Ivo J. H.; Hulshof, Carel T. J.; Frings-Dresen, Monique H. W.

2008-03-01

Direct observation, instead of using self-administered questionnaires might give more reliable and specific information about physical work demands at the workplace. This information is of use in a population already at risk of developing low back pain (LBP) due to whole body vibration (WBV) exposure. The aims of this study are to assess the WBV exposure in an exposed population and to assess other physical work demands in two ways, by direct observation and with the use of a self-administered questionnaire. We therefore assessed the WBV magnitude and 5 WBV-related physical work demands by using the PalmTrac system and a self-administered questionnaire in a group of drivers ( N=10). The main findings are 7 out of 10 drivers are exceeding the EU action value. About 50% of the drivers under-estimated the time 'bending', 60% the time 'walking+standing' and 60% over-estimated the time when 'lifting.' We concluded that 7 drivers from this group are at risk of developing LBP and substantial differences exists for the 5 physical work demands comparing the PalmTrac method with the questionnaire. Direct observational assessment in WBV measurements yields extra information. This is useful for preventive activities necessary as drivers are exceeding the EU action value.

The fraction of total hand surface area involved in young children's outdoor hand-to-object contacts.

PubMed

AuYeung, Willa; Canales, Robert A; Leckie, James O

2008-11-01

Information on the fraction of total hand surface area touching a contaminated object is necessary in accurately estimating contaminant (e.g., pesticides, pathogens) loadings onto the hands during hand-to-object contacts. While several existing physical-stochastic human exposure models require such surface area data to estimate dermal and non-dietary ingestion exposure, there are very limited data sets. This paper provides statistical distributions of fractional surface areas (FSAs) for children's outdoor hand contacts. These distributions were constructed by combining information collected from two distinct studies exploring children's activity patterns and quantifying hand contact surface area. Results show that for outdoor contacts with "All Objects", a range of 0.13-0.27 captured median FSAs, while a range of 0.12-0.24 captured time-weighted FSAs. Overall, an FSA of 0.31 captured 80-100% of FSAs involved in each child's outdoor hand contacts, depending upon the object of interest. These values are much lower than the often conservative assumptions of up to 1 (i.e., the entire hand) that researchers currently make regarding FSAs involved in indoor and outdoor contacts [USEPA, 1997. Standard operating procedures (SOPs) for residential exposure assessments. Contract no. 68-W6-0030. http://www.epa.gov/pesticides/trac/science/trac6a05.pdf].

Millimeter Wave Nonreciprocal Devices.

DTIC Science & Technology

1983-01-03

measures microwave magnetic field patterns of magnetostatic waves in LPE -YIG thin films has been developed. The probe’s sensing element is either a...Morgenthaler, "Workshop on Application of Garnet and Ferrite Thin Films to Microwave Devices," Session FC, Third Joint Intermag - Magnetism and...thin films Li... millimeter waves magnetostati c waves i A TRAC" =CmE4 F*91040 eEp y mnenu -d Dfenvely by Noek n.m--) The Microwave and Quantum

Force 2025 and Beyond Strategic Force Design Analytic Model

DTIC Science & Technology

2017-01-12

depiction of the core ideas of our force design model. Figure 1: Description of Force Design Model Figure 2 shows an overview of our methodology ...the F2025B Force Design Analytic Model research conducted by TRAC- MTRY and the Naval Postgraduate School. Our research develops a methodology for...designs. We describe a data development methodology that characterizes the data required to construct a force design model using our approach. We

West Europe Report.

DTIC Science & Technology

1987-01-12

Daimler-Benz trac- tor division. Westdeutsche Landesbank got the Lentjes group and machine tool manufacturer Gildemeister together. Almost all the big...banks placed calls to 63 year-old Otto Waldrich in Co- burg, the owner of a profitable machine tool plant. His "is a family-owned business without...consideration to a case which, is nearly 25 years old. Without any wish to reopen old wounds, I would like to take advantage of this occasion to write

Evaluation of the WavTrac Expeditionary Mobility Matting System

DTIC Science & Technology

2017-04-01

pavement applications. Designation D6951. West Conshohocken, PA: ASTM International. www.astm.org. Rushing, T. W., and J. F. Rowland. 2012. Comparison of...respective owners. The findings of this report are not to be construed as an official Department of the Army position unless so designated by other...The technical monitor was Jeb S. Tingle. The work was performed by the Airfields and Pavements Branch (APB) of the Engineering Systems and Materials

MIST final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gloudemans, J.R.

1991-08-01

The multiloop integral system test (MIST) was part of a multiphase program started in 1983 to address small-break loss-of-coolant accidents (SBLOCAs) specific to Babcock Wilcox-designed plants. MIST was sponsored by the US Nuclear Regulatory Commission, the Babcock Wilcox Owners Group, the Electric Power Research Institute, and Babcock Wilcox. The unique features of the Babcock Wilcox design, specifically the hot leg U-bends and steam generators, prevented the use of existing integral system data or existing integral system facilities to addresss the thermal-hydraulic SBLOCA questions. MIST was specifically designed and constructed for this program, and an existing facility -- the once-through integralmore » system (OTIS) -- was also used. Data from MIST and OTIS are used to benchmark the adequacy of system codes, such as RELAP5 and TRAC, for predicting abnormal plant transients. The MIST program is reported in eleven volumes; Volumes 2 through 8 pertain to groups of Phase 3 tests by type, Volume 9 presents inter-group comparisons. Volume 10 provides comparisons between the RELAP5 MOD2 calculations and MIST observations, and Volume 11 (with addendum) presents the later, Phase 4 tests. This is Volume 1 of the MIST final report, a summary of the entire MIST program. Major topics include: test advisory grop (TAG) issues; facility scaling and design; test matrix; observations; comparisons of RELAP5 calculations to MIST observations; and MIST versus the TAG issues. 11 refs., 29 figs., 9 tabs.« less

Collecting wrappers, labels, and packages to enhance accuracy of food records among children 2-8 years in the Pacific region: Children's Healthy Living Program (CHL).

PubMed

Yonemori, Kim M; Ennis, Tui; Novotny, Rachel; Fialkowski, Marie K; Ettienne, Reynolette; Wilkens, Lynne R; Leon Guerrero, Rachael T; Bersamin, Andrea; Coleman, Patricia; Li, Fenfang; Boushey, Carol J

2017-12-01

The aim was to describe differences in dietary outcomes based on the provision of food wrappers, labels or packages (WLP) to complement data from dietary records (DR) among children from the US Affiliated Pacific. The WLP were intended to aid food coding. Since WLP can be associated with ultra-processed foods, one might expect differences in sodium, sugar, and other added ingredients to emerge. Dietary intakes of children (2-8 y) in Alaska, Hawai'i, Commonwealth of the Northern Mariana Islands, and Guam were collected using parent/caregiver completed 2-day DR. Parents were encouraged to collect WLP associated with the child's intake. Trained staff entered data from the DRs including the WLP when available using PacTrac3, a web application. Of the 1,868 DRs collected and entered at the time of this report, 498 (27%) included WLP. After adjusting for confounders (sex, age, location, education, food assistance), the DRs with WLP had significantly higher amounts of energy (kcal), total fat, saturated fat, added sugar, and sodium. These results suggest the inclusion of WLP enhanced the dietary intake data. The intake of energy, fat, added sugar and sodium derived from processed foods and foods consumed outside the home was better captured in children who had WLP.

Predictions of Critical Heat Flux in Annular Pipes with TRACEv4.160 code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jasiulevicius, Audrius; Macian-Juan, Rafael

2006-07-01

This paper presents the assessment of TRACE (version v4.160) against the Critical Heat Flux (CHF) experiments in annular tubes performed at the Royal Institute of Technology (KTH) in Stockholm, Sweden. The experimental database includes data for coolant mass fluxes between 250 and 2500 kg/m{sup 2}s and inlet subcooling of 10 and 40 K at a pressure of 70 bar. The work presented in this paper supplements the calculations of single round tube experiments carried out earlier and provides a broader scope of validated geometries. In addition to the Biasi and CISE-GE CHF correlations available in the code, a number ofmore » experimental points at low flow conditions are available for the annular geometry experiments, which also permitted the assessment of the Biasi/Zuber CHF correlation used in TRACE v4.160 for low flow conditions. Experiments with different axial power distribution were simulated and the effects of the axial power profile and the coolant inlet subcooling on the TRACE predictions were investigated. The results of this work show that the Biasi/Zuber correlation provides good estimation of the CHF at 70 bar, and, for the same conditions, the simulation of the annular experiments resulted in the calculation of lower CHF values compared to single-tube experiments. The analysis of the performance of the standard TRACE CHF correlations shows that the CISE-GE correlation yields critical qualities (quality at CHF) closer to the experimental values at 70 bar than the Biasi correlation for annular flow conditions. Regarding the power profile, the results of the TRACE calculations seem to be very sensitive to its shape, since, depending on the profile, different accuracies in the predictions were noted while other system conditions remained constant. The inlet coolant subcooling was also an important factor in the accuracy of TRACE CHF predictions. Thus, an increase in the inlet subcooling led to a clear improvement in the estimation of the critical quality with both Biasi and CISE-GE correlations. To complement the work, three additional CHF correlations were implemented in TRACE v4.160, namely the Bowring, Tong W-3 and Levitan-Lantsman CHF models, in order to assess the applicability of these correlations to simulate the CHF in annular tubes. The improvement of CHF predictions for low coolant mass flows (up to 1500 kg/m{sup 2}s) is noted when applying Bowring CHF correlation. However, the increase in the inlet subcooling increases the error in predicted critical quality with the Bowring correlation. The Levitan-Lantsman and Tong-W-3 correlations provide results similar to the Biasi model. Therefore, the most correct CHF predictions among the investigated correlations were obtained using CISE-GE model in the standard TRAC v4.160 code. (authors)« less

Traction Aid for Wheeled Vehicles

DTIC Science & Technology

1975-07-01

driver’s position in the load vehicle to assist him in applying constant braking loads, 4) a drum and line fifth wheel sys- tem attached to the load...in Alaskan snow, and the results were so encouraging that further testing of the device was requested. In comparison to tire chains, the Tyr-Trac...vehicle with the end of the line anchored and the speed of the line played off the drum measuring the actual vehicle speed. An eight channel

Determination of the Microscopic Structure of Surface and Overlayers, Adsorbate-Adsorbate Interaction Energies, and Rates of Surface Processes.

DTIC Science & Technology

1982-12-28

molecular beam-surface scattering, high pressure microreactor , heterogeneous catalysis. :116. AmTRAC? ’CAuI1ae 4111, 8ee 1 111 It oesey -1lP d ify by...Crystallography.. . ..... ....................... 4 11. Design and Construction of a High Pressure Catalvtic Microreactor ... microreactor has been designed and constructed. This micro- reactor will be a useful adjunct to the molecular beam machine since in the former overall

Towards a Formal Semantics of Flight Plans and Trajectories

NASA Technical Reports Server (NTRS)

Hagen, George E.; Butler, Ricky W.

2014-01-01

In the National Airspace System, ight plans are often used only as a planning tool by air trac controllers and aircraft operators. These plans are implicitly translated into trajectories by the pilot or by the ight management system, and subsequently own by the aircraft. This translation process inevitably introduces di erences between the plan and the trajectory. However, given the current intended usage, exact correspondence between the plan and the trajectory is not needed. To achieve greater capacity and eciency, future air trac management concepts are being designed around the use of trajectories where predictability is extremely important. In this paper, a mathematical relationship between ight plans and trajectories is explored with the goal of making feasible, highly accurate predictions of future positions and velocities of aircraft. The goal here is to describe, in mathematically precise detail, a formal language of trajectories, whereby all receivers of the trajectory information will be able to arrive at precisely the same trajectory predication and to do this without having aircraft broadcast a large amount of data. Although even a four-dimensional ight plan is simple in structure, this paper will show that it is inherently ambiguous and will explore these issues in detail. In e ect, we propose that a rigorous semantics for ight plans can be developed and this will serve as an important stepping stone towards trajectory-based operations in the National Airspace System.

The fraction of total hand surface area involved in young children's outdoor hand-to-object contacts

DOE Office of Scientific and Technical Information (OSTI.GOV)

AuYeung, Willa; Canales, Robert A.; Leckie, James O.

2008-11-15

Information on the fraction of total hand surface area touching a contaminated object is necessary in accurately estimating contaminant (e.g., pesticides, pathogens) loadings onto the hands during hand-to-object contacts. While several existing physical-stochastic human exposure models require such surface area data to estimate dermal and non-dietary ingestion exposure, there are very limited data sets. This paper provides statistical distributions of fractional surface areas (FSAs) for children's outdoor hand contacts. These distributions were constructed by combining information collected from two distinct studies exploring children's activity patterns and quantifying hand contact surface area. Results show that for outdoor contacts with 'All Objects',more » a range of 0.13-0.27 captured median FSAs, while a range of 0.12-0.24 captured time-weighted FSAs. Overall, an FSA of 0.31 captured 80-100% of FSAs involved in each child's outdoor hand contacts, depending upon the object of interest. These values are much lower than the often conservative assumptions of up to 1 (i.e., the entire hand) that researchers currently make regarding FSAs involved in indoor and outdoor contacts [USEPA, 1997. Standard operating procedures (SOPs) for residential exposure assessments. Contract no. 68-W6-0030. < (http://www.epa.gov/pesticides/trac/science/trac6a05.pdf)>].« less

Pictorial Format Display Evaluation

DTIC Science & Technology

1984-05-01

FIGR) under- Contract No. F33615-81-C-3610. Dr. John M. Reising served as Project Manager .with Capt. Carole Jean Kopala and, later, Major James S...Typo (SAM or AAA) Mode (Seahr, trac or launch) Air or Troak or Treat Type (MIG 21, MIK 23. SAM. or AAA" aa le Iunc Mode (Sara, trock or- lmxch) Clock...presentation (l pilot). Should come up automatically (I pilot). Airplane this smart should be able to fix these problems and just announce fix (1 pilot

What Should Users Expect from Information Storage and Retrieval Systems of the 1980’s

DTIC Science & Technology

1981-12-01

cide dcentrer sur ls marchE de l1information secondaire, on doit d~finir Is secteur , rschercher des appuis (coop~rants) pour couvrir cc secteur ...inutiles. Ii appartient bien entendu chaque Gouvernemant dlapprdcier sea prioritds, mais en se plagant dans Is cadre tracE. GOUVERNEMENT ET SECTEUR PRIVE A...directive A76 salon laqualle le Gouvernament f~d~ral slappuiera sur Is secteur priv6 pour publiar at dissminar llinformation scientifique at technique

Helmet Mounted Eye Tracking for Virtual Panoramic Displays. Volume 1: Review of Current Eye Movement Measurement Technology

DTIC Science & Technology

1989-08-01

paths for integration with the off-aperture and dual-mirror VPD designs. PREFACE The goal of this work was to explore integration of an eye line-of- gaze ...Relationship in one plane between point-of- gaze on a flat scene and relative eye, detector, and scene positions...and eye line-of- gaze measurement. As a first step towards the design of an appropriate eye trac.<ing system for interface with the virtual cockpit

Forwarding Pointers for Efficient Location Management in Distributed Mobile Environments

DTIC Science & Technology

1994-09-01

signalling trac on the SS7 signalling system(capacity of 56 Kbps) is expected to be 4-11 times greater for cellular networks than for ISDN and3-4 times...load. Thus location updatewill become a major bottleneck at the switches (such as SS7 ) and mechanisms to control the costof location update are...ACM, pp. 19-28, Oct. 1994.16 [3] Kathleen S. Meier-Hellstern, et. al., \\The Use of SS7 and GSM to support high density per-sonal communications

GRASS GIS: a peer-reviewed scientific platform and future research repository

NASA Astrophysics Data System (ADS)

Chemin, Yann; Petras, Vaclav; Petrasova, Anna; Landa, Martin; Gebbert, Sören; Zambelli, Pietro; Neteler, Markus; Löwe, Peter; Di Leo, Margherita

2015-04-01

Geographical Information System (GIS) is known for its capacity to spatially enhance the management of natural resources. While being often used as an analytical tool, it also represents a collaborative scientific platform to develop new algorithms. Thus, it is critical that GIS software as well as the algorithms are open and accessible to anybody [18]. We present how GRASS GIS, a free and open source GIS, is used by many scientists to implement and perform geoprocessing tasks. We will show how integrating scientific algorithms into GRASS GIS helps to preserve reproducibility of scientific results over time [15]. Moreover, subsequent improvements are tracked in the source code version control system and are immediately available to the public. GRASS GIS therefore acts as a repository of scientific peer-reviewed code, algorithm library, and knowledge hub for future generation of scientists. In the field of hydrology, with the various types of actual evapotranspiration (ET) models being developed in the last 20 years, it becomes necessary to inter-compare methods. Most of already published ETa models comparisons address few number of models, and small to medium areas [3, 6, 7, 22, 23]. With the large amount of remote sensing data covering the Earth, and the daily information available for the past ten years (i.e. Aqua/Terra-MODIS) for each pixel location, it becomes paramount to have a more complete comparison, in space and time. To address this new experimental requirement, a distributed computing framework was designed, and created [3, 4]. The design architecture was built from original satellite datasets to various levels of processing until reaching the requirement of various ETa models input dataset. Each input product is computed once and reused in all ETa models requiring such input. This permits standardization of inputs as much as possible to zero-in variations of models to the models internals/specificities. All of the ET models are available in the new GRASS GIS version 7 as imagery modules and replicability is complete for future research. A set of modules for multiscale analysis of landscape structure was added in 1992 by [1], who developed the r.le model similar to FRAGSTATS ([10]). The modules were gradually improved to become r.li in 2006. Further development continued, with a significant speed up [9] and new interactive user interface. The development of spatial interpolation module v.surf.rst started in 1988 [11] and continued by introduction of new interpolation methods and finally full integration into GRASS GIS version 4 [13]. Since then it was improved several times [8]. The module is an important part of GRASS GIS and is taught at geospatial modeling courses, for example at North Carolina State University [14]. GRASS GIS entails several modules that constitute the result of active research on natural hazard. The r.sim.water simulation model [12] for overland flow under rainfall excess conditions was integrated into the Emergency Routing Decision Planning system as a WPS [17]. It was also utilized by [16] and is now part of Tangible Landscape, a tangible GIS system, which also incorporated the r.damflood, a dam break inundation simulation [2]. The wildfire simulation toolset, originally developed by [24], implementing Rothermel's model [21], available through the GRASS GIS modules r.ros and r.spread, is object of active research. It has been extensively tested and recently adapted to European fuel types ([5, 19, 20]). References [1] Baker, W.L., Cai, Y., 1992. The r.le programs for multiscale analysis of landscape structure using the GRASS geographical information system. Landscape Ecology, 7(4):291-302. [2] Cannata M. and Marzocchi R., 2012. Two-dimensional dam break flooding simulation: a GIS embedded approach. - Natural Hazards 61(3):1143-1159. [3] Chemin, Y.H., 2012. A Distributed Benchmarking Framework for Actual ET Models. In Evapotranspiration - Remote Sensing and Modeling, Intech (Eds). [4] Chemin, Y. H. , 2014. Remote Sensing Raster Programming, 3rd Ed., Lulu (Eds). [5] Di Leo, M., de Rigo, D., Rodriguez-Aseretto, D., Bosco, C., Petroliagkis, T., Camia, A., San-Miguel-Ayanz, J., 2013. Dynamic data driven ensemble for wildfire behaviour assessment: A case study. IFIP Advances in Information and Communication Technology, vol. 413, pp. 11-22, 2013, ISSN:1868-4238. Special issue: "Environmental Software Systems. Fostering sharing information". [6] García, M., Villagarcía, L., Contreras, S., Domingo, F. & Puigdefábregas, J. (2007). Comparison of three operative models for estimating the surface water deficit using aster reflective and thermal data, Sensors 7(6): 860-883. [7] Gao, Y. & Long, D. ,2008. Intercomparison of remote sensing-based models for estimation of evapotranspiration and accuracy assessment based on swat, Hydrological Processes 22: 4850-4869. [8] GRASS GIS Trac, changelog for v.surf.rst, 2015. http://trac.osgeo.org/grass/ [9] GRASS GIS Trac, changelog for r.li, 2015. http://trac.osgeo.org/grass/ [10] McGarigal, K., and B. J. Marks. 1995. FRAGSTATS: spatial pattern analysis program for quantifying landscape structure. USDA For. Serv. Gen. Tech. Rep. PNW-351 [11] Mitas, L., and Mitasova H., 1988, General variational approach to the approximation problem, Computers and Mathematics with Applications, v.16, p. 983-992. [12] Mitas, L., and Mitasova, H., 1998, Distributed soil erosion simulation for effective erosion prevention. Water Resources Research, 34(3), 505-516. [13] Mitasova, H. and Mitas, L., 1993: Interpolation by Regularized Spline with Tension: I. Theory and Implementation, Mathematical Geology, 25, 641-655. [14] North Carolina State University, Geospatial Modeling Course, GIS/MEA582, 2015. http://courses.ncsu.edu/ [15] Petras, V., Gebbert, S., 2014. Testing framework for GRASS GIS: ensuring reproducibility of scientific geospatial computing. Poster presented at: AGU Fall Meeting, December 15-19, 2014, San Francisco, USA. [16] Petrasova, A., Harmon, B., Petras, V., Mitasova, H., 2014. GIS-based environmental modeling with tangible interaction and dynamic visualization. In: Ames, D.P., Quinn, N.W.T., Rizzoli, A.E. (Eds.), Proceedings of the 7th International Congress on Environmental Modelling and Software, June 15-19, San Diego, California, USA. ISBN: 978-88-9035-744-2 [17] Raghavan, v., Choosumrong, S., Yoshida, D., Vinayaraj, P., 2014. Deploying Dynamic Routing Service for Emergency Scenarios using pgRouting, GRASS and ZOO. In Proc. of FOSS4G Europe, Jacobs University, Bremen, Germany, July 15-17, 2014. [18] Rocchini, D., Neteler, M. ,2012. Let the four freedoms paradigm apply to ecology. Trends in Ecology & Evolution, 27: 310-311. [19] Rodriguez-Aseretto, D., de Rigo, D., Di Leo, M., Cortés, A., and San-Miguel-Ayanz, J., 2013. A data-driven model for large wildfire behaviour prediction in europe. Procedia Computer Science, vol. 18, pp. 1861-1870. [20] de Rigo, D., Rodriguez-Aseretto, D., Bosco, C., Di Leo, M., and San-Miguel-Ayanz, J., 2013. An architecture for adaptive robust modelling of wildfire behaviour under deep uncertainty. in Environmental Software Systems. Fostering Information Sharing, ser. IFIP Advances in Information and Communication Technology, J. Ȟrebíˇ cek, G. Schimak, M. Kubásek, and A. Rizzoli, Eds. Springer Berlin Heidelberg, 2013, vol. 413, pp. 367-380. [21] Rothermel, R. C., 1983. How to predict the spread and intensity of forest and range fires. US Forest Service, Gen. Tech. Rep. INT-143. Ogden, Utah. [22] Suleiman, A., Al-Bakri, J., Duqqah, M. & Crago, R. ,2008. Intercomparison ofevapotranspiration estimates at the different ecological zones in jordan, Journal of Hydrometeorology 9(5): 903-919. [23] Timmermans, W. J., Kustas, W. P., Anderson, M. C. & French, A. N. ,2007. An intercomparison of the surface energy balance algorithm for land (sebal) and the two-source energy balance (tseb) modeling schemes, Remote Sensing of Environment 108(4): 369 - 384. [24] Xu, Jianping, 1994. Simulating the spread of wildfires using a geographic information system and remote sensing. Ph. D. Dissertation, Rutgers University, New Brunswick, New Jersey.

Adjuvant Vascular Endothelial Growth Factor-targeted Therapy in Renal Cell Carcinoma: A Systematic Review and Pooled Analysis.

PubMed

Sun, Maxine; Marconi, Lorenzo; Eisen, Tim; Escudier, Bernard; Giles, Rachel H; Haas, Naomi B; Harshman, Lauren C; Quinn, David I; Larkin, James; Pal, Sumanta K; Powles, Thomas; Ryan, Christopher W; Sternberg, Cora N; Uzzo, Robert; Choueiri, Toni K; Bex, Axel

2018-05-18

Contradictory data exist with regard to adjuvant vascular endothelial growth factor receptor (VEGFR)-targeted therapy in surgically managed patients for localized renal cell carcinoma (RCC). To systematically evaluate the current evidence regarding the therapeutic benefit (disease-free survival [DFS] and overall survival [OS]) and grade 3-4 adverse events (AEs) for adjuvant VEGFR-targeted therapy for resected localized RCC. A critical review of PubMed/Medline, Embase, and the Cochrane Library in January 2018 according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement was performed. We identified reports and reviewed them according to the Consolidated Standards of Reporting Trials and Standards for the Reporting of Diagnostic Accuracy Studies criteria. Of eight full-text articles that were eligible for inclusion, five studies (two of five were updated analyses) were retained in the final synthesis. Study characteristics were abstracted and the number needed to treat (NNT) per trial was estimated. The three randomized controlled phase III trials included the following comparisons: sunitinib versus placebo or sorafenib versus placebo (Adjuvant Sorafenib or Sunitinib for Unfavorable Renal Carcinoma [ASSURE] study, n=1943), sunitinib versus placebo (S-TRAC, n=615), and pazopanib versus placebo (Pazopanib As Adjuvant Therapy in Localized/Locally Advanced RCC After Nephrectomy study, n=1135). The NNT ranged from 10 (S-TRAC) to 137 (ASSURE study). The pooled analysis showed that VEGFR-targeted therapy was not statistically significantly associated with improved DFS (hazard ratio [HR random ]: 0.92, 95% confidence interval [CI]: 0.82-1.03, p=0.16) or OS (HR random : 0.98, 95% CI: 0.84-1.15, p=0.84) compared with the control group. The adjuvant therapy group experienced significantly higher odds of grade 3-4 AEs (OR random : 5.89, 95% CI: 4.85-7.15, p<0.001). In exploratory analyses focusing on patients who started on the full-dose regimen, DFS was improved in patients who received adjuvant therapy (HR random : 0.83, 95% CI: 0.73-0.95, p=0.005). This pooled analysis of reported randomized trials did not reveal a statistically significant effect between adjuvant VEGFR-targeted therapy and improved DFS or OS in patients with intermediate/high-risk local or regional fully resected RCC. Improvement in DFS may be more likely with the use of full-dose regimens, pending further results. However, adjuvant treatment was associated with high-grade AEs. Vascular endothelial growth factor receptor-targeted therapy after nephrectomy for localized kidney cancer is not associated with consistent improvements in delaying cancer recurrence or prolonging life and comes at the expense of potentially significant side effects. Copyright © 2018 European Association of Urology. Published by Elsevier B.V. All rights reserved.

Intravenous flurbiprofen axetil can stabilize the hemodynamic instability due to mesenteric traction syndrome--evaluation with continuous measurement of the systemic vascular resistance index using a FloTrac® sensor.

PubMed

Takada, Motoshi; Taruishi, Chieko; Sudani, Tomoko; Suzuki, Akira; Iida, Hiroki

2013-08-01

Evaluation of the stabilizing effect of intravenous flurbiprofen axetil against hemodynamic instability due to mesenteric traction syndrome (MTS) by continuous measurement of systemic vascular resistance index (SVRI) using a FloTrac(®) sensor was evaluated. Prospective randomized trial. A single-center study performed in an educational hospital. Two prospective studies were carried out, each with 40 patients scheduled for elective open abdominal surgery. Twenty patients received 50 mg of flurbiprofen axetil after the recognition of MTS by the anesthesiologist (group FT). The remaining patients served as controls (groups CP and CT). SVRI data was collected every 20 seconds for 1 hour after starting the laparotomy. The average SVRI prior to skin incision was taken as the baseline. Following 3 values were devised to evaluate MTS: the S-value (sum total of changes in SVRI from baseline), the T-value (period during which SVRI remained 20% or more below baseline), and the M-value (maximum change in SVRI from baseline). In group FP, decrease in SVRI was smaller than in group CP, and statistical differences in the 3 values were found. In group FT, SVRI recovered earlier than in group CT, and statistical differences were found in S-value and T-value. However, the M-value had no statistical differences. Intravenous flurbiprofen axetil can stabilize the hemodynamic instability due to MTS. Copyright © 2013 Elsevier Inc. All rights reserved.

Preliminary study on the relationships between aboveground storage and remotely sensed data at Pingdong plain afforestation land in Southern Taiwan

NASA Astrophysics Data System (ADS)

Wei, C.; Chen, J. M.; Yu, J.; Cheng, C.; Lai, Y.; Chiang, P.; Hong, C.; Chang, C.; Wey, T.; Tsai, M.; Wang, Y.

2013-12-01

This research aims on the relationships between LAI and five vegetation index (BR, SRBR, BD, NDVI and TNDVI) from remotely sensed images, in situ measurements and aboveground storage for 10-11yr old plain afforestation (14 species) located at Wanlong farm of subtropical-tropical region at the southern part of Taiwan which originally governed by Taiwan Sugar Corporation. The preliminary results show the aboveground storage is 14.19×9.19 m3 ha-1 and the correlation coefficient between aboveground storage and BR, SRBR, BD, NDVI and TNDVI is 0.331 (p=0.211), 0.317 (p=0.232), 0.310 (p=0.244), 0.714 (p=0.002) and 0.706 (p=0.002) while NDVI performs the best correlation. LAI value using Fisheye or Tracing Radiation and Architecture of Canopies (TRAC) is 0.76×0.37 and 3.89×2.81, respectively. Besides, CI measured by TRAC is 0.83×0.09 and the correlation coefficient with LAI is 0.868 (p<0.001). It shows feasible to estimate aboveground storage using ground investigation incorporating remotely sensed data for young plain afforestation stand. Due to the mixed-plantation and difference between growing and non-growing season at the sample site, the relationship between aboveground storage, LAI and VI is yet to be developed for independent species and may need to modify due to seasonally and inter-annually variation.

Accuracy of Calories Indicated on 7 Commercially Available Exercise Machines

DTIC Science & Technology

2013-12-02

the results of the testing of 7 devices: Precor EFX Elliptical, Precor UBK800 Bike, Octane 4700 Elliptical, Star Track E-UB Bike, Star Track E- TBT ...Star Track E- TBT Low Medium High Cadence 65-75 65-75 60-70 Work Level ♂ 5-8 10-13 15-18 ♀ 4-6 8-11 13-15 Results: Two of the devices...588 (.370, .806) .910 1.164 Star Trac E- TBT 2.750 (-.200, 5.700) .659 (.416, .902) .899 .970 Note: CI = confidence interval Figure 2.0 shows the

Accuracy of stroke volume variation in predicting fluid responsiveness: a systematic review and meta-analysis.

PubMed

Zhang, Zhongheng; Lu, Baolong; Sheng, Xiaoyan; Jin, Ni

2011-12-01

Stroke volume variation (SVV) appears to be a good predictor of fluid responsiveness in critically ill patients. However, a wide range of its predictive values has been reported in recent years. We therefore undertook a systematic review and meta-analysis of clinical trials that investigated the diagnostic value of SVV in predicting fluid responsiveness. Clinical investigations were identified from several sources, including MEDLINE, EMBASE, WANFANG, and CENTRAL. Original articles investigating the diagnostic value of SVV in predicting fluid responsiveness were considered to be eligible. Participants included critically ill patients in the intensive care unit (ICU) or operating room (OR) who require hemodynamic monitoring. A total of 568 patients from 23 studies were included in our final analysis. Baseline SVV was correlated to fluid responsiveness with a pooled correlation coefficient of 0.718. Across all settings, we found a diagnostic odds ratio of 18.4 for SVV to predict fluid responsiveness at a sensitivity of 0.81 and specificity of 0.80. The SVV was of diagnostic value for fluid responsiveness in OR or ICU patients monitored with the PiCCO or the FloTrac/Vigileo system, and in patients ventilated with tidal volume greater than 8 ml/kg. SVV is of diagnostic value in predicting fluid responsiveness in various settings.

The development and implementation of the structured training programme for caregivers of inpatients after stroke (TRACS) intervention: the London Stroke Carers Training Course.

PubMed

Forster, Anne; Dickerson, Josie; Melbourn, Anne; Steadman, Jayne; Wittink, Margreet; Young, John; Kalra, Lalit; Farrin, Amanda

2015-03-01

To describe the content and delivery of the adapted London Stroke Carers Training Course intervention evaluated in the Training Caregivers after Stroke (TRACS) trial. The London Stroke Carers Training Course is a structured training programme for caregivers of inpatients who are likely to return home after their stroke. The course was delivered by members of the multidisciplinary team while the patient was in the stroke unit with one recommended 'follow through' session after discharge home. The intervention consists of 14 training components (six mandatory) that were identified as important knowledge/skills that caregivers would need to be able to care for the stroke patient after discharge home. Following national training days, the London Stroke Carers Training Course was disseminated to intervention sites by the cascade method of implementation. The intervention was adapted for implementation across a range of stroke units. Training days were well attended (median 2.5 and 2.0 attendees per centre for the first and second days, respectively) and the feedback positive, demonstrating 'face validity' for the intervention. However cascading of this training to other members of the multidisciplinary team was not consistent, with 7/18 centres recording no cascade training. The adapted London Stroke Carers Training Course provided a training programme that could be delivered in a standardised, structured way in a variety of stroke unit settings throughout the UK. The intervention was well received by stroke unit staff, however, the cascade method of implementation was not as effective as we would have wished. © The Author(s) 2014.

The LEAP™ Gesture Interface Device and Take-Home Laparoscopic Simulators: A Study of Construct and Concurrent Validity.

PubMed

Partridge, Roland W; Brown, Fraser S; Brennan, Paul M; Hennessey, Iain A M; Hughes, Mark A

2016-02-01

To assess the potential of the LEAP™ infrared motion tracking device to map laparoscopic instrument movement in a simulated environment. Simulator training is optimized when augmented by objective performance feedback. We explore the potential LEAP has to provide this in a way compatible with affordable take-home simulators. LEAP and the previously validated InsTrac visual tracking tool mapped expert and novice performances of a standardized simulated laparoscopic task. Ability to distinguish between the 2 groups (construct validity) and correlation between techniques (concurrent validity) were the primary outcome measures. Forty-three expert and 38 novice performances demonstrated significant differences in LEAP-derived metrics for instrument path distance (P < .001), speed (P = .002), acceleration (P < .001), motion smoothness (P < .001), and distance between the instruments (P = .019). Only instrument path distance demonstrated a correlation between LEAP and InsTrac tracking methods (novices: r = .663, P < .001; experts: r = .536, P < .001). Consistency of LEAP tracking was poor (average % time hands not tracked: 31.9%). The LEAP motion device is able to track the movement of hands using instruments in a laparoscopic box simulator. Construct validity is demonstrated by its ability to distinguish novice from expert performances. Only time and instrument path distance demonstrated concurrent validity with an existing tracking method however. A number of limitations to the tracking method used by LEAP have been identified. These need to be addressed before it can be considered an alternative to visual tracking for the delivery of objective performance metrics in take-home laparoscopic simulators. © The Author(s) 2015.

Validation of the Spatial Accuracy of the ExacTracRTM Adaptive Gating System

NASA Astrophysics Data System (ADS)

Twork, Gregory

Stereotactic body radiation therapy (SBRT) is a method of treatment that is used in extracranial locations, including the abdominal and thoracic cavities, as well as spinal and paraspinal locations. At the McGill University Health Centre, liver SBRT treatments include gating, which places the treatment beam on a duty cycle controlled by tracking of fiducial markers moving with the patient's breathing cycle. Respiratory gated treatments aim to spare normal tissue, while delivering a dose properly to a moving target. The ExacTracRTM system (BrainLAB AG Germany) is an image-guided radiotherapy system consisting of a combination of infra-red (IR) cameras and dual kilovoltage (kV) X-ray tubes. The IR system is used to track patient positioning and respiratory motion, while the kV X-rays are used to determine a positional shift based on internal anatomy or fiducial markers. In order to validate the system's ability to treat under gating conditions, each step of the SBRT process was evaluated quantitatively. Initially the system was tested under ideal static conditions, followed by a study including gated parameters. The uncertainties of the isocenters, positioning algorithm, planning computed tomography (CT) and four dimensional CT (4DCT) scans, gating window size and tumor motion were evaluated for their contributions to the total uncertainty in treatment. The mechanical isocenter and 4DCT were found to be the largest sources of uncertainty. However, for tumors with large internal amplitudes (>2.25 cm) that are treated with large gating windows (>30%) the gating parameters can contribute more than 1.1 +/- 1.8 mm.

Photon caliper to achieve submillimeter positioning accuracy

NASA Astrophysics Data System (ADS)

Gallagher, Kyle J.; Wong, Jennifer; Zhang, Junan

2017-09-01

The purpose of this study was to demonstrate the feasibility of using a commercial two-dimensional (2D) detector array with an inherent detector spacing of 5 mm to achieve submillimeter accuracy in localizing the radiation isocenter. This was accomplished by delivering the Vernier ‘dose’ caliper to a 2D detector array where the nominal scale was the 2D detector array and the non-nominal Vernier scale was the radiation dose strips produced by the high-definition (HD) multileaf collimators (MLCs) of the linear accelerator. Because the HD MLC sequence was similar to the picket fence test, we called this procedure the Vernier picket fence (VPF) test. We confirmed the accuracy of the VPF test by offsetting the HD MLC bank by known increments and comparing the known offset with the VPF test result. The VPF test was able to determine the known offset within 0.02 mm. We also cross-validated the accuracy of the VPF test in an evaluation of couch hysteresis. This was done by using both the VPF test and the ExacTrac optical tracking system to evaluate the couch position. We showed that the VPF test was in agreement with the ExacTrac optical tracking system within a root-mean-square value of 0.07 mm for both the lateral and longitudinal directions. In conclusion, we demonstrated the VPF test can determine the offset between a 2D detector array and the radiation isocenter with submillimeter accuracy. Until now, no method to locate the radiation isocenter using a 2D detector array has been able to achieve such accuracy.

Nansen Station Data for the Indian and Pacific Oceans 1982 to 1987

DTIC Science & Technology

1989-09-01

with GMS and NOAA satellite derived values. Diagrams of SST versus cumulat;ve ship distance travelled foi the Kin’ola cruises are available from the...88 THIS IS A BLANK PAGE WSRL-TM-30/88 12 *50*E 15- 16 2 3 35* 6s 7\\-S 1 6 10 HANSEN STATION Pow rIoHs 12 112 - CRUISE TRAC11 4 -.. TRAVEL DIRECTION A...included in the present report. Contamination of samples by salps appeared to be the cause. Other sources of data for cruise RANRL 24183 Hamilton, L.J

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyack, B.E.; Steiner, J.L.; Harmony, S.C.

The PIUS advanced reactor is a 640-MWe pressurized water reactor concept developed by Asea Brown Boveri. A unique feature of PIUS is the absence of mechanical control and shutdown rods. Reactivity is controlled by coolant boron concentration and the temperature of the moderator coolant. Los Alamos supported the US Nuclear Regulatory Commission`s preapplication review of the PIUS reactor. Baseline calculations of the PIUS design were performed for active and passive reactor scrams using TRAC-PF1/MOD2. Additional sensitivity studies examined flow blockage and boron dilution events to explore the robustness of the PIUS concept for low-probability combination events following active-system scrams.

Observations Regarding Use of Advanced CFD Analysis, Sensitivity Analysis, and Design Codes in MDO

NASA Technical Reports Server (NTRS)

Newman, Perry A.; Hou, Gene J. W.; Taylor, Arthur C., III

1996-01-01

Observations regarding the use of advanced computational fluid dynamics (CFD) analysis, sensitivity analysis (SA), and design codes in gradient-based multidisciplinary design optimization (MDO) reflect our perception of the interactions required of CFD and our experience in recent aerodynamic design optimization studies using CFD. Sample results from these latter studies are summarized for conventional optimization (analysis - SA codes) and simultaneous analysis and design optimization (design code) using both Euler and Navier-Stokes flow approximations. The amount of computational resources required for aerodynamic design using CFD via analysis - SA codes is greater than that required for design codes. Thus, an MDO formulation that utilizes the more efficient design codes where possible is desired. However, in the aerovehicle MDO problem, the various disciplines that are involved have different design points in the flight envelope; therefore, CFD analysis - SA codes are required at the aerodynamic 'off design' points. The suggested MDO formulation is a hybrid multilevel optimization procedure that consists of both multipoint CFD analysis - SA codes and multipoint CFD design codes that perform suboptimizations.

Sci-Thur AM: YIS – 07: Optimizing dual-energy x-ray parameters using a single filter for both high and low-energy images to enhance soft-tissue imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bowman, Wesley; Sattarivand, Mike

Objective: To optimize dual-energy parameters of ExacTrac stereoscopic x-ray imaging system for lung SBRT patients Methods: Simulated spectra and a lung phantom were used to optimize filter material, thickness, kVps, and weighting factors to obtain bone subtracted dual-energy images. Spektr simulations were used to identify material in the atomic number (Z) range [3–83] based on a metric defined to separate spectrums of high and low energies. Both energies used the same filter due to time constraints of image acquisition in lung SBRT imaging. A lung phantom containing bone, soft tissue, and a tumor mimicking material was imaged with filter thicknessesmore » range [0–1] mm and kVp range [60–140]. A cost function based on contrast-to-noise-ratio of bone, soft tissue, and tumor, as well as image noise content, was defined to optimize filter thickness and kVp. Using the optimized parameters, dual-energy images of anthropomorphic Rando phantom were acquired and evaluated for bone subtraction. Imaging dose was measured with dual-energy technique using tin filtering. Results: Tin was the material of choice providing the best energy separation, non-toxicity, and non-reactiveness. The best soft-tissue-only image in the lung phantom was obtained using 0.3 mm tin and [140, 80] kVp pair. Dual-energy images of the Rando phantom had noticeable bone elimination when compared to no filtration. Dose was lower with tin filtering compared to no filtration. Conclusions: Dual-energy soft-tissue imaging is feasible using ExacTrac stereoscopic imaging system utilizing a single tin filter for both high and low energies and optimized acquisition parameters.« less

Effect of fluid loading on left ventricular volume and stroke volume variability in patients with end-stage renal disease: a pilot study

PubMed Central

Kanda, Hirotsugu; Hirasaki, Yuji; Iida, Takafumi; Kanao-Kanda, Megumi; Toyama, Yuki; Kunisawa, Takayuki; Iwasaki, Hiroshi

2015-01-01

Purpose The aim of this study was to investigate fluid loading-induced changes in left ventricular end-diastolic volume (LVEDV) and stroke volume variability (SVV) in patients with end-stage renal disease (ESRD) using real-time three-dimensional transesophageal echocardiography and the Vigileo-FloTrac system. Patients and methods After obtaining ethics committee approval and informed consent, 28 patients undergoing peripheral vascular procedures were studied. Fourteen patients with ESRD on hemodialysis (HD) were assigned to the HD group and 14 patients without ESRD were assigned to the control group. Institutional standardized general anesthesia was provided in both groups. SVV was measured using the Vigileo-FloTrac system. Simultaneously, a full-volume three-dimensional transesophageal echocardiography dataset was acquired to measure LVEDV, left ventricular end-systolic volume, and left ventricular ejection fraction. Measurements were obtained before and after loading 500 mL hydroxyethyl starch over 30 minutes in both groups. Results In the control group, intravenous colloid infusion was associated with a significant decrease in SVV (13.8%±2.6% to 6.5%±2.6%, P<0.001) and a significant increase in LVEDV (83.6±23.4 mL to 96.1±28.8 mL, P<0.001). While SVV significantly decreased after infusion in the HD group (16.2%±6.0% to 6.2%±2.8%, P<0.001), there was no significant change in LVEDV. Conclusion Our preliminary data suggest that fluid responsiveness can be assessed not by LVEDV but also by SVV due to underlying cardiovascular pathophysiology in patients with ESRD. PMID:26527879

Accuracy of an infrared marker-based patient positioning system (ExacTrac®) for stereotactic body radiotherapy in localizing the planned isocenter using fiducial markers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Montes-Rodríguez, María de los Ángeles, E-mail: angy24538@yahoo.com; Mitsoura, Eleni; Hernández-Bojórquez, Mariana

2014-11-07

Stereotactic Body Radiation Therapy (SBRT) requires a controlled immobilization and position monitoring of patient and target. The purpose of this work is to analyze the performance of the imaging system ExacTrac® (ETX) using infrared and fiducial markers. Materials and methods: In order to assure the accuracy of isocenter localization, a Quality Assurance procedure was applied using an infrared marker-based positioning system. Scans were acquired of an inhouse-agar gel and solid water phantom with infrared spheres. In the inner part of the phantom, three reference markers were delineated as reference and one pellet was place internally; which was assigned as themore » isocenter. The iPlan® RT Dose treatment planning system. Images were exported to the ETX console. Images were acquired with the ETX to check the correctness of the isocenter placement. Adjustments were made in 6D the reference markers were used to fuse the images. Couch shifts were registered. The procedure was repeated for verification purposes. Results: The data recorded of the verifications in translational and rotational movements showed averaged 3D spatial uncertainties of 0.31 ± 0.42 mm respectively 0.82° ± 0.46° in the phantom and the first correction of these uncertainties were of 1.51 ± 1.14 mm respectively and 1.37° ± 0.61°. Conclusions: This study shows a high accuracy and repeatability in positioning the selected isocenter. The ETX-system for verifying the treatment isocenter position has the ability to monitor the tracing position of interest, making it possible to be used for SBRT positioning within uncertainty ≤1mm.« less

Fresno Air Terminal, California. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

DTIC Science & Technology

1981-01-15

34 *,"- *< " + "-o:"- I *13 C. -"-d+J °0 ’ A4 *+ *" - "~ ._______+: .+ ..G+ ., .2+ .- + tD .: rrgC 67 .. .+ .- -- T C’ TRAC 690 l1ei1. -+ _ *d ef . 5 .t CU L...3;M’d4 JitrET&: SURFACE WINDS 11 Z TD ,T-.[ 5IVIIE/A: PERCENTAGE FREQUENCY OF WIND DIRECTION AND SPEED (FROM HOURLY OBSEVATIONS) STATIO1N V"AT O NAM...041.5 (OL.A) PNvICUs contom1co tins JooN om ossouiti A I - - - - - -- - - - - - - - - - - -__ _ _ _ _ _ _ _ _ _ -_ _ _ _ U : LI4& TD ...3SY 3RA4𔃾 -211

ATCA-based ATLAS FTK input interface system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Okumura, Yasuyuki; Liu, Tiehui Ted; Olsen, Jamieson

The first stage of the ATLAS Fast TracKer (FTK) is an ATCA-based input interface system, where hits from the entire silicon tracker are clustered and organized into overlapping eta-phi trigger towers before being sent to the tracking engines. First, FTK Input Mezzanine cards receive hit data and perform clustering to reduce data volume. Then, the ATCA-based Data Formatter system will organize the trigger tower data, sharing data among boards over full mesh backplanes and optic fibers. The board and system level design concepts and implementation details, as well as the operation experiences from the FTK full-chain testing, will be presented.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyack, B.E.; Steiner, J.L.; Harmony, S.C.

The PIUS advanced reactor is a 640-MWe pressurized water reactor concept developed by Asea Brown Boveri. A unique feature of PIUS is the absence of mechanical control and shutdown rods. Reactivity is controlled by coolant boron concentration and the temperature of the moderator coolant. Los Alamos is supporting the US Nuclear Regulatory Commission`s preapplication review of the PIUS reactor. Baseline calculations of the PIUS design were performed for a loss of offsite power initiator using TRAC-PF1/MOD2. Additional sensitivity studies examined flow blockage and boron dilution events to explore the robustness of the PIUS concept for low-probability combination events following amore » loss of offsite power.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steiner, J.L.; Harmony, S.C.; Stumpf, H.J.

The PIUS advanced reactor is a 640-MWe pressurized water reactor concept developed by Asea Brown Boveri. A unique feature of PIUS is the absence of mechanical control and shutdown rods. Reactivity is controlled by coolant boron concentration and the temperature of the moderator coolant. Los Alamos is supporting the US Nuclear Regulatory Commission`s preapplication review of the PIUS reactor. Baseline calculations of the PIUS Supplement design were performed for a large-break loss-of-coolant (LBLOCA) initiator using TRAC-PF1/MOD2. Additional sensitivity studies examined flow blockage and boron dilution events to explore the robustness of the PIUS concept for low-probability combination events following anmore » LBLOCA.« less

Cervical spine fractures in patients 65 years or older: a 3-year experience at a level I trauma center.

PubMed

Damadi, Amir A; Saxe, Andrew W; Fath, John J; Apelgren, Keith N

2008-03-01

Cervical spine fractures in the elderly carry a mortality as high as 26%. We reviewed our experience to define the level of injury, prevalence of neurologic deficits, treatments employed, and the correlation between patients' pre- and posthospital residences. Also, we correlated the prevalence of advanced directives with length of stay. We queried the data collected prospectively at an American College of Surgeons verified Level I hospital (National TRACS, American College of Surgeons) regarding patients aged 65 years or older presenting with cervical spine fractures (International Classification of Diseases-9 code 805.X) in calendar years 2000 through 2003. We identified 58 patients (ages 65-94). Mortality was 24%. Twelve patients had quadriplegia or paraplegia and seven of these patients died. Respiratory failure was the primary cause of death. Application of rigid collars and a halo brace were the most commonly employed therapies. Mortality rates for halo stabilization and rigid collar and halo stabilization were similar (23% vs. 29%). Despite having a higher mean Injury Severity Score, the 16 patients with advanced directives had an intensive care unit length of stay similar to that of patients without advanced directives but a statistically significant shorter overall length of stay (13 vs. 6.9 days). Eighteen of 45 patients living at home at the time of injury returned home. Cervical spine injury in the elderly does not inevitably relegate patients to a setting of more acute nursing care. The health and social factors that allowed many to return to living at home warrant investigation, as support of these factors may assist others with this injury.

A Text Message Intervention with Adaptive Goal Support to Reduce Alcohol Consumption Among Non-Treatment-Seeking Young Adults: Non-Randomized Clinical Trial with Voluntary Length of Enrollment.

PubMed

Suffoletto, Brian; Chung, Tammy; Muench, Frederick; Monti, Peter; Clark, Duncan B

2018-02-16

Stand-alone text message-based interventions can reduce binge drinking episodes (≥4 drinks for women and ≥5 drinks for men) among nontreatment-seeking young adults, but may not be optimized. Adaptive text message support could enhance effectiveness by assisting context-specific goal setting and striving, but it remains unknown how to best integrate it into text message interventions. The objective of this study was to evaluate young adults' engagement with a text message intervention, Texting to Reduce Alcohol Consumption 2 (TRAC2), which focuses on reducing weekend alcohol consumption. TRAC2 incorporated preweekend drinking-limit goal-commitment ecological momentary assessments (EMA) tailored to past 2-week alcohol consumption, intraweekend goal reminders, self-efficacy EMA with support tailored to goal confidence, and maximum weekend alcohol consumption EMA with drinking limit goal feedback. We enrolled 38 nontreatment-seeking young adults (aged 18 to 25 years) who screened positive for hazardous drinking in an urban emergency department. Following a 2-week text message assessment-only run-in, subjects were given the opportunity to enroll in 4-week intervention blocks. We examined patterns of EMA responses and voluntary re-enrollment. We then examined how goal commitment and goal self-efficacy related to event-level alcohol consumption. Finally, we examined the association of length of TRAC2 exposure with alcohol-related outcomes from baseline to 3-month follow-up. Among a diverse sample of young adults (56% [28/50] female, 54% [27/50] black, 32% [12/50] college enrolled), response rates to EMA queries were, on average, 82% for the first 4-week intervention block, 75% for the second 4-week block, and 73% for the third 4-week block. In the first 4 weeks of the intervention, drinking limit goal commitment was made 68/71 times it was prompted (96%). The percentage of subjects being prompted to commit to a drinking limit goal above the binge threshold was 52% (15/29) in week 1 and decreased to 0% (0/15) by week 4. Subjects met their goal 130/146 of the times a goal was committed to (89.0%). There were lower rates of goal success when subjects reported lower confidence (score <4) in meeting the goal (76% [32/42 weekends]) compared with that when subjects reported high confidence (98% [56/57 weekends]; P=.001). There were reductions in alcohol consumption from baseline to 3 months, but reductions were not different by length of intervention exposure. Preliminary evidence suggests that nontreatment-seeking young adults will engage with a text message intervention incorporating self-regulation support features, resulting in high rates of weekend drinking limit goal commitment and goal success. ©Brian Suffoletto, Tammy Chung, Frederick Muench, Peter Monti, Duncan B Clark. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 16.02.2018.

X-Antenna: A graphical interface for antenna analysis codes

NASA Technical Reports Server (NTRS)

Goldstein, B. L.; Newman, E. H.; Shamansky, H. T.

1995-01-01

This report serves as the user's manual for the X-Antenna code. X-Antenna is intended to simplify the analysis of antennas by giving the user graphical interfaces in which to enter all relevant antenna and analysis code data. Essentially, X-Antenna creates a Motif interface to the user's antenna analysis codes. A command-file allows new antennas and codes to be added to the application. The menu system and graphical interface screens are created dynamically to conform to the data in the command-file. Antenna data can be saved and retrieved from disk. X-Antenna checks all antenna and code values to ensure they are of the correct type, writes an output file, and runs the appropriate antenna analysis code. Volumetric pattern data may be viewed in 3D space with an external viewer run directly from the application. Currently, X-Antenna includes analysis codes for thin wire antennas (dipoles, loops, and helices), rectangular microstrip antennas, and thin slot antennas.

Methodology for fast detection of false sharing in threaded scientific codes

DOEpatents

Chung, I-Hsin; Cong, Guojing; Murata, Hiroki; Negishi, Yasushi; Wen, Hui-Fang

2014-11-25

A profiling tool identifies a code region with a false sharing potential. A static analysis tool classifies variables and arrays in the identified code region. A mapping detection library correlates memory access instructions in the identified code region with variables and arrays in the identified code region while a processor is running the identified code region. The mapping detection library identifies one or more instructions at risk, in the identified code region, which are subject to an analysis by a false sharing detection library. A false sharing detection library performs a run-time analysis of the one or more instructions at risk while the processor is re-running the identified code region. The false sharing detection library determines, based on the performed run-time analysis, whether two different portions of the cache memory line are accessed by the generated binary code.

An error analysis perspective for patient alignment systems.

PubMed

Figl, Michael; Kaar, Marcus; Hoffman, Rainer; Kratochwil, Alfred; Hummel, Johann

2013-09-01

This paper analyses the effects of error sources which can be found in patient alignment systems. As an example, an ultrasound (US) repositioning system and its transformation chain are assessed. The findings of this concept can also be applied to any navigation system. In a first step, all error sources were identified and where applicable, corresponding target registration errors were computed. By applying error propagation calculations on these commonly used registration/calibration and tracking errors, we were able to analyse the components of the overall error. Furthermore, we defined a special situation where the whole registration chain reduces to the error caused by the tracking system. Additionally, we used a phantom to evaluate the errors arising from the image-to-image registration procedure, depending on the image metric used. We have also discussed how this analysis can be applied to other positioning systems such as Cone Beam CT-based systems or Brainlab's ExacTrac. The estimates found by our error propagation analysis are in good agreement with the numbers found in the phantom study but significantly smaller than results from patient evaluations. We probably underestimated human influences such as the US scan head positioning by the operator and tissue deformation. Rotational errors of the tracking system can multiply these errors, depending on the relative position of tracker and probe. We were able to analyse the components of the overall error of a typical patient positioning system. We consider this to be a contribution to the optimization of the positioning accuracy for computer guidance systems.

BOREAS RSS-7 LAI, Gap Fraction, and FPAR Data

NASA Technical Reports Server (NTRS)

Hall, Forrest G. (Editor); Nickeson, Jaime (Editor); Chen, Jing

2000-01-01

The BOREAS RSS-7 team collected various data sets to develop and validate an algorithm to allow the retrieval of the spatial distribution of Leaf Area Index (LAI) from remotely sensed images. Ground measurements of LAI and Fraction of Photosynthetically Active Radiation (FPAR) absorbed by the plant canopy were made using the LAI-2000 and TRAC optical instruments during focused periods from 09-Aug-1993 to 19-Sep-1994. The measurements were intensive at the NSA and SSA tower sites, but were made just once or twice at auxiliary sites. The final processed LAI and FPAR data set is contained in tabular ASCII files. The data files are available on a CD-ROM (see document number 20010000884).

Network analysis for the visualization and analysis of qualitative data.

PubMed

Pokorny, Jennifer J; Norman, Alex; Zanesco, Anthony P; Bauer-Wu, Susan; Sahdra, Baljinder K; Saron, Clifford D

2018-03-01

We present a novel manner in which to visualize the coding of qualitative data that enables representation and analysis of connections between codes using graph theory and network analysis. Network graphs are created from codes applied to a transcript or audio file using the code names and their chronological location. The resulting network is a representation of the coding data that characterizes the interrelations of codes. This approach enables quantification of qualitative codes using network analysis and facilitates examination of associations of network indices with other quantitative variables using common statistical procedures. Here, as a proof of concept, we applied this method to a set of interview transcripts that had been coded in 2 different ways and the resultant network graphs were examined. The creation of network graphs allows researchers an opportunity to view and share their qualitative data in an innovative way that may provide new insights and enhance transparency of the analytical process by which they reach their conclusions. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Posttest analysis of the FFTF inherent safety tests

DOE Office of Scientific and Technical Information (OSTI.GOV)

Padilla, A. Jr.; Claybrook, S.W.

Inherent safety tests were performed during 1986 in the 400-MW (thermal) Fast Flux Test Facility (FFTF) reactor to demonstrate the effectiveness of an inherent shutdown device called the gas expansion module (GEM). The GEM device provided a strong negative reactivity feedback during loss-of-flow conditions by increasing the neutron leakage as a result of an expanding gas bubble. The best-estimate pretest calculations for these tests were performed using the IANUS plant analysis code (Westinghouse Electric Corporation proprietary code) and the MELT/SIEX3 core analysis code. These two codes were also used to perform the required operational safety analyses for the FFTF reactormore » and plant. Although it was intended to also use the SASSYS systems (core and plant) analysis code, the calibration of the SASSYS code for FFTF core and plant analysis was not completed in time to perform pretest analyses. The purpose of this paper is to present the results of the posttest analysis of the 1986 FFTF inherent safety tests using the SASSYS code.« less

GRABGAM Analysis of Ultra-Low-Level HPGe Gamma Spectra

DOE Office of Scientific and Technical Information (OSTI.GOV)

Winn, W.G.

The GRABGAM code has been used successfully for ultra-low level HPGe gamma spectrometry analysis since its development in 1985 at Savannah River Technology Center (SRTC). Although numerous gamma analysis codes existed at that time, reviews of institutional and commercial codes indicated that none addressed all features that were desired by SRTC. Furthermore, it was recognized that development of an in-house code would better facilitate future evolution of the code to address SRTC needs based on experience with low-level spectra. GRABGAM derives its name from Gamma Ray Analysis BASIC Generated At MCA/PC.

The influence of technological parameters on the dynamic behavior of "liquid wood" samples obtained by injection molding

NASA Astrophysics Data System (ADS)

Plavanescu Mazurchevici, Simona; Carausu, Constantin; Comaneci, Radu; Nedelcu, Dumitru

2017-10-01

The plastic products contribute to environmental pollution. Replacing the plastic materials with biodegradable materials with superior properties is an absolute necessity and important research direction for the near future. The first steps in this regard were the creation of composite materials containing natural fibers with positive effects on the environment that have penetrated in different fields. The bioplastics and biocomposites made from natural fibers is a topical solution. The next step was made towards obtaining biodegradable and recyclable materials based on cellulose, lignin and no carcinogens. In this category fall the "liquid wood" with a use up to five times without affecting the mechanical properties. "Liquid wood" is a high quality thermoplastic biocomposite. "Liquid wood" is a biopolymer composite divided in three categories, ARBOFORM®, ARBOBLEND® and ARBOFILL®, which have differed composition in terms of lignin percentage, being delivered by Tecnaro, as granules, [1]. The paper's research was focus on Arboform L V3 Nature and Arboform L V3 Nature reinforced with aramid fiber. In the experimental plan were taken into account six parameters (Dinj - direction of injection [°]; Ttop - melting temperature [°C]; Pinj - injection pressure [MPa] Ss - speed [m/min]; tinj - injection time [s] and tc - cooling time [s]) each with two levels, research carried on by Taguchi methodology. Processing Taguchi method allowed both Taguchi setting work parameters influence on storage modulus and damping as the size and influence their ranking. Experimental research concerning the influence technological parameters on storage modulus of samples obtained by injection from Arboform L V3 Nature yielded an average of 6055MPa and descending order as follows: Trac, Ss, Pinj, Dinj and Ttop. The average of model for reinforced material was 6419MPa and descending order of parameters influence such as: Dinj, Trac, Ttop, tinj, Ss and Pinj.

Characteristics of School Campuses and Physical Activity Among Youth

PubMed Central

Cradock, Angie L.; Melly, Steven J.; Allen, Joseph G.; Morris, Jeffrey S.; Gortmaker, Steven L.

2009-01-01

Background Previous research suggests that school characteristics may influence physical activity. However, few studies have examined associations between school building and campus characteristics and objective measures of physical activity among middle school students. Methods Students from ten middle schools (n=248, 42% female, mean age 13.7 years) wore TriTrac-R3D accelerometers in 1997 recording measures of minute-by-minute physical movements during the school day that were then averaged over 15-minute intervals (n=16,619) and log-transformed. School characteristics, including school campus area, play area, and building area (per student) were assessed retrospectively in 2004–2005 using land-use parcel data, site visits, ortho-photos, architectural plans, and site maps. In 2006, linear mixed models using SAS PROC MIXED were fit to examine associations between school environmental variables and physical activity, controlling for potentially confounding variables. Results Area per enrolled student ranged from 8.8 to 143.7 m2 for school campuses, from 12.1 to 24.7 m2 for buildings, and from 0.4 to 58.9 m2 for play areas. Play area comprised from 3% to 62% of total campus area across schools. In separate regression models, school campus area per student (β=0.2244, p<0.0001); building area per student (β=2.1302, p<0.02); and play area per student (β=0.347, p<0.0001) were each directly associated with log-TriTrac-R3D vector magnitude. Given the range of area density measures in this sample of schools, this translates into an approximate 20% to 30% increase in average vector magnitude, or walking 2 extra miles over the course of a week. Conclusions Larger school campuses, school buildings, and play areas (per enrolled student) are associated with higher levels of physical activity in middle school students. PMID:17673097

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tanabe, S; Utsunomiya, S; Abe, E

Purpose: To assess an accuracy of fiducial maker-based setup using ExacTrac (ExT-based setup) as compared with soft tissue-based setup using Cone-beam CT (CBCT-based setup) for patients with prostate cancer receiving intensity-modulated radiation therapy (IMRT) for the purpose of investigating whether ExT-based setup can be an alternative to CBCT-based setup. Methods: The setup accuracy was analyzed prospectively for 7 prostate cancer patients with implanted three fiducial markers received IMRT. All patients were treated after CBCT-based setup was performed and corresponding shifts were recorded. ExacTrac images were obtained before and after CBCT-based setup. The fiducial marker-based shifts were calculated based on thosemore » two images and recorded on the assumption that the setup correction was carried out by fiducial marker-based auto correction. Mean and standard deviation of absolute differences and the correlation between CBCT and ExT shifts were estimated. Results: A total of 178 image dataset were analyzed. On the differences between CBCT and ExT shifts, 133 (75%) of 178 image dataset resulted in smaller differences than 3 mm in all dimensions. Mean differences in the anterior-posterior (AP), superior-inferior (SI), and left-right (LR) dimensions were 1.8 ± 1.9 mm, 0.7 ± 1.9 mm, and 0.6 ± 0.8 mm, respectively. The percentages of shift agreements within ±3 mm were 76% for AP, 90% for SI, and 100% for LR. The Pearson coefficient of correlation for CBCT and ExT shifts were 0.80 for AP, 0.80 for SI, and 0.65 for LR. Conclusion: This work showed that the accuracy of ExT-based setup was correlated with that of CBCT-based setup, implying that ExT-based setup has a potential ability to be an alternative to CBCT-based setup. The further work is to specify the conditions that ExT-based setup can provide the accuracy comparable to CBCT-based setup.« less

Hanford tank initiative vehicle/based waste retrieval demonstration report phase II, track 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berglin, E.J.

1997-07-31

Using the versatile TracPUMpTm, Environmental Specialties Group, LLC (ES) performed a successful Phase 11 demonstration of a Vehicle- Based Waste Retrieval System (VWRS) for removal of waste material and residual liquid found in the Hanford Underground Storage Tanks (ousts). The purpose of this demonstration was to address issues pertaining to the use of a VWRS in OUSTS. The demonstration also revealed the waste removal capabilities of the TracPumpTm and the most effective techniques and equipment to safely and effectively remove waste simulants. ES successfully addressed the following primary issues: I . Dislodge and convey the waste forms present in themore » Hanford OUSTS; 2. Access the UST through tank openings as small as twenty-four inches in diameter; 3. Traverse a variety of terrains including slopes, sludges, rocks and hard, slippery surfaces without becoming mired; 4. Dislodge and convey waste within the confinement of the Decontamination Containment Capture Vessel (DCCV) and with minimal personnel exposure; 5. Decontaminate equipment to acceptable limits during retrieval from the UST; 6. Perform any required maintenance within the confinement of the DCCV; and 7. Maintain contaminate levels ``as low as reasonably achievable`` (ALARA) within the DCCV due to its crevice and comer-free design. The following materials were used to simulate the physical characteristics of wastes found in Hanford`s OUSTS: (1) Hardpan: a clay-type material that has high shear strength; (2) Saltcake: a fertilizer-based material that has high compressive strength; and (3) Wet Sludge.- a sticky, peanut- butter- like material with low shear strength. Four test beds were constructed of plywood and filled with a different simulant to a depth of eight to ten inches. Three of the test beds were of homogenous simulant material, while the fourth bed consisted of a mixture of all three simulant types.« less

Integrated Composite Analyzer (ICAN): Users and programmers manual

NASA Technical Reports Server (NTRS)

Murthy, P. L. N.; Chamis, C. C.

1986-01-01

The use of and relevant equations programmed in a computer code designed to carry out a comprehensive linear analysis of multilayered fiber composites is described. The analysis contains the essential features required to effectively design structural components made from fiber composites. The inputs to the code are constituent material properties, factors reflecting the fabrication process, and composite geometry. The code performs micromechanics, macromechanics, and laminate analysis, including the hygrothermal response of fiber composites. The code outputs are the various ply and composite properties, composite structural response, and composite stress analysis results with details on failure. The code is in Fortran IV and can be used efficiently as a package in complex structural analysis programs. The input-output format is described extensively through the use of a sample problem. The program listing is also included. The code manual consists of two parts.

Reliable absolute analog code retrieval approach for 3D measurement

NASA Astrophysics Data System (ADS)

Yu, Shuang; Zhang, Jing; Yu, Xiaoyang; Sun, Xiaoming; Wu, Haibin; Chen, Deyun

2017-11-01

The wrapped phase of phase-shifting approach can be unwrapped by using Gray code, but both the wrapped phase error and Gray code decoding error can result in period jump error, which will lead to gross measurement error. Therefore, this paper presents a reliable absolute analog code retrieval approach. The combination of unequal-period Gray code and phase shifting patterns at high frequencies are used to obtain high-frequency absolute analog code, and at low frequencies, the same unequal-period combination patterns are used to obtain the low-frequency absolute analog code. Next, the difference between the two absolute analog codes was employed to eliminate period jump errors, and a reliable unwrapped result can be obtained. Error analysis was used to determine the applicable conditions, and this approach was verified through theoretical analysis. The proposed approach was further verified experimentally. Theoretical analysis and experimental results demonstrate that the proposed approach can perform reliable analog code unwrapping.

A Semantic Analysis Method for Scientific and Engineering Code

NASA Technical Reports Server (NTRS)

Stewart, Mark E. M.

1998-01-01

This paper develops a procedure to statically analyze aspects of the meaning or semantics of scientific and engineering code. The analysis involves adding semantic declarations to a user's code and parsing this semantic knowledge with the original code using multiple expert parsers. These semantic parsers are designed to recognize formulae in different disciplines including physical and mathematical formulae and geometrical position in a numerical scheme. In practice, a user would submit code with semantic declarations of primitive variables to the analysis procedure, and its semantic parsers would automatically recognize and document some static, semantic concepts and locate some program semantic errors. A prototype implementation of this analysis procedure is demonstrated. Further, the relationship between the fundamental algebraic manipulations of equations and the parsing of expressions is explained. This ability to locate some semantic errors and document semantic concepts in scientific and engineering code should reduce the time, risk, and effort of developing and using these codes.

Genetic Code Analysis Toolkit: A novel tool to explore the coding properties of the genetic code and DNA sequences

NASA Astrophysics Data System (ADS)

Kraljić, K.; Strüngmann, L.; Fimmel, E.; Gumbel, M.

2018-01-01

The genetic code is degenerated and it is assumed that redundancy provides error detection and correction mechanisms in the translation process. However, the biological meaning of the code's structure is still under current research. This paper presents a Genetic Code Analysis Toolkit (GCAT) which provides workflows and algorithms for the analysis of the structure of nucleotide sequences. In particular, sets or sequences of codons can be transformed and tested for circularity, comma-freeness, dichotomic partitions and others. GCAT comes with a fertile editor custom-built to work with the genetic code and a batch mode for multi-sequence processing. With the ability to read FASTA files or load sequences from GenBank, the tool can be used for the mathematical and statistical analysis of existing sequence data. GCAT is Java-based and provides a plug-in concept for extensibility. Availability: Open source Homepage:http://www.gcat.bio/

FEAMAC/CARES Stochastic-Strength-Based Damage Simulation Tool for Ceramic Matrix Composites

NASA Technical Reports Server (NTRS)

Nemeth, Noel; Bednarcyk, Brett; Pineda, Evan; Arnold, Steven; Mital, Subodh; Murthy, Pappu; Bhatt, Ramakrishna

2016-01-01

Reported here is a coupling of two NASA developed codes: CARES (Ceramics Analysis and Reliability Evaluation of Structures) with the MAC/GMC (Micromechanics Analysis Code/ Generalized Method of Cells) composite material analysis code. The resulting code is called FEAMAC/CARES and is constructed as an Abaqus finite element analysis UMAT (user defined material). Here we describe the FEAMAC/CARES code and an example problem (taken from the open literature) of a laminated CMC in off-axis loading is shown. FEAMAC/CARES performs stochastic-strength-based damage simulation response of a CMC under multiaxial loading using elastic stiffness reduction of the failed elements.

Stochastic-Strength-Based Damage Simulation Tool for Ceramic Matrix Composite

NASA Technical Reports Server (NTRS)

Nemeth, Noel; Bednarcyk, Brett; Pineda, Evan; Arnold, Steven; Mital, Subodh; Murthy, Pappu

2015-01-01

Reported here is a coupling of two NASA developed codes: CARES (Ceramics Analysis and Reliability Evaluation of Structures) with the MAC/GMC (Micromechanics Analysis Code/ Generalized Method of Cells) composite material analysis code. The resulting code is called FEAMAC/CARES and is constructed as an Abaqus finite element analysis UMAT (user defined material). Here we describe the FEAMAC/CARES code and an example problem (taken from the open literature) of a laminated CMC in off-axis loading is shown. FEAMAC/CARES performs stochastic-strength-based damage simulation response of a CMC under multiaxial loading using elastic stiffness reduction of the failed elements.

Aerothermo-Structural Analysis of Low Cost Composite Nozzle/Inlet Components

NASA Technical Reports Server (NTRS)

Shivakumar, Kuwigai; Challa, Preeli; Sree, Dave; Reddy, D.

1999-01-01

This research is a cooperative effort among the Turbomachinery and Propulsion Division of NASA Glenn, CCMR of NC A&T State University, and the Tuskegee University. The NC A&T is the lead center and Tuskegee University is the participating institution. Objectives of the research were to develop an integrated aerodynamic, thermal and structural analysis code for design of aircraft engine components, such as, nozzles and inlets made of textile composites; conduct design studies on typical inlets for hypersonic transportation vehicles and setup standards test examples and finally manufacture a scaled down composite inlet. These objectives are accomplished through the following seven tasks: (1) identify the relevant public domain codes for all three types of analysis; (2) evaluate the codes for the accuracy of results and computational efficiency; (3) develop aero-thermal and thermal structural mapping algorithms; (4) integrate all the codes into one single code; (5) write a graphical user interface to improve the user friendliness of the code; (6) conduct test studies for rocket based combined-cycle engine inlet; and finally (7) fabricate a demonstration inlet model using textile preform composites. Tasks one, two and six are being pursued. Selected and evaluated NPARC for flow field analysis, CSTEM for in-depth thermal analysis of inlets and nozzles and FRAC3D for stress analysis. These codes have been independently verified for accuracy and performance. In addition, graphical user interface based on micromechanics analysis for laminated as well as textile composites was developed. Demonstration of this code will be made at the conference. A rocket based combined cycle engine was selected for test studies. Flow field analysis of various inlet geometries were studied. Integration of codes is being continued. The codes developed are being applied to a candidate example of trailblazer engine proposed for space transportation. A successful development of the code will provide a simpler, faster and user-friendly tool for conducting design studies of aircraft and spacecraft engines, applicable in high speed civil transport and space missions.

An emulator for minimizing computer resources for finite element analysis

NASA Technical Reports Server (NTRS)

Melosh, R.; Utku, S.; Islam, M.; Salama, M.

1984-01-01

A computer code, SCOPE, has been developed for predicting the computer resources required for a given analysis code, computer hardware, and structural problem. The cost of running the code is a small fraction (about 3 percent) of the cost of performing the actual analysis. However, its accuracy in predicting the CPU and I/O resources depends intrinsically on the accuracy of calibration data that must be developed once for the computer hardware and the finite element analysis code of interest. Testing of the SCOPE code on the AMDAHL 470 V/8 computer and the ELAS finite element analysis program indicated small I/O errors (3.2 percent), larger CPU errors (17.8 percent), and negligible total errors (1.5 percent).

Wake coupling to full potential rotor analysis code

NASA Technical Reports Server (NTRS)

Torres, Francisco J.; Chang, I-Chung; Oh, Byung K.

1990-01-01

The wake information from a helicopter forward flight code is coupled with two transonic potential rotor codes. The induced velocities for the near-, mid-, and far-wake geometries are extracted from a nonlinear rigid wake of a standard performance and analysis code. These, together with the corresponding inflow angles, computation points, and azimuth angles, are then incorporated into the transonic potential codes. The coupled codes can then provide an improved prediction of rotor blade loading at transonic speeds.

Comparative analysis of design codes for timber bridges in Canada, the United States, and Europe

Treesearch

James Wacker; James (Scott) Groenier

2010-01-01

The United States recently completed its transition from the allowable stress design code to the load and resistance factor design (LRFD) reliability-based code for the design of most highway bridges. For an international perspective on the LRFD-based bridge codes, a comparative analysis is presented: a study addressed national codes of the United States, Canada, and...

Land mobile communications in Ku-band - Results of a test campaign on Eutelsat I-F1

NASA Astrophysics Data System (ADS)

Dutronc, J.; Colcy, J. N.

1990-02-01

This paper discusses the results of technical tests on land mobile communications conducted in June and July 1989 in Europe using a Eutelsat satellite. The land-mobile communication system under test was that already operated by QUALCOMM in the U.S. under the registered name OmniTRACS. The aim of the field trial was to evaluate the technical characteristics of the system and test its performance in different operating conditions. The results establish the relationship between transmission performance (i.e. essentially the required number of transmission attempts in order to get a message through the communication channel), and the environment of the land mobile, the satellite transponder's mode of operations and the interference conditions.

Monitoring of cyclosporine concentrations by using dry blood-spot samples.

PubMed

Mee, A V; Wong, P Y; Sun, C; Oei, L; Elliott, S; Naik, N; Joaquin, B; Uchimaru, D

1991-01-01

We modified the Incstar Cyclo Trac SP kit to enable its use with dry blood-spots on filter paper. The recovery ranged from 92 to 106%. Dilution studies have shown excellent linearity and parallelism throughout the range of the assay. Precision is demonstrated by within-assay CV's of 6.6 and 4.3% at 96 and 342 micrograms/L respectively and between-assay CV's of 9.1 and 7.0% at 138 and 506 micrograms/L respectively. A comparison study (n = 209) with whole blood assay gave a correlation coefficient of 0.97, a slope of 1.04, and an intercept of 13.2. Whole blood and dry blood-spot cyclosporine assays on heart, kidney, liver, and lung transplants were also compared.

Non-targeted analysis of unexpected food contaminants using LC-HRMS.

PubMed

Kunzelmann, Marco; Winter, Martin; Åberg, Magnus; Hellenäs, Karl-Erik; Rosén, Johan

2018-03-29

A non-target analysis method for unexpected contaminants in food is described. Many current methods referred to as "non-target" are capable of detecting hundreds or even thousands of contaminants. However, they will typically still miss all other possible contaminants. Instead, a metabolomics approach might be used to obtain "true non-target" analysis. In the present work, such a method was optimized for improved detection capability at low concentrations. The method was evaluated using 19 chemically diverse model compounds spiked into milk samples to mimic unknown contamination. Other milk samples were used as reference samples. All samples were analyzed with UHPLC-TOF-MS (ultra-high-performance liquid chromatography time-of-flight mass spectrometry), using reversed-phase chromatography and electrospray ionization in positive mode. Data evaluation was performed by the software TracMass 2. No target lists of specific compounds were used to search for the contaminants. Instead, the software was used to sort out all features only occurring in the spiked sample data, i.e., the workflow resembled a metabolomics approach. Procedures for chemical identification of peaks were outside the scope of the study. Method, study design, and settings in the software were optimized to minimize manual evaluation and faulty or irrelevant hits and to maximize hit rate of the spiked compounds. A practical detection limit was established at 25 μg/kg. At this concentration, most compounds (17 out of 19) were detected as intact precursor ions, as fragments or as adducts. Only 2 irrelevant hits, probably natural compounds, were obtained. Limitations and possible practical use of the approach are discussed.

Comparison of two computer codes for crack growth analysis: NASCRAC Versus NASA/FLAGRO

NASA Technical Reports Server (NTRS)

Stallworth, R.; Meyers, C. A.; Stinson, H. C.

1989-01-01

Results are presented from the comparison study of two computer codes for crack growth analysis - NASCRAC and NASA/FLAGRO. The two computer codes gave compatible conservative results when the part through crack analysis solutions were analyzed versus experimental test data. Results showed good correlation between the codes for the through crack at a lug solution. For the through crack at a lug solution, NASA/FLAGRO gave the most conservative results.

Full 3D visualization tool-kit for Monte Carlo and deterministic transport codes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frambati, S.; Frignani, M.

2012-07-01

We propose a package of tools capable of translating the geometric inputs and outputs of many Monte Carlo and deterministic radiation transport codes into open source file formats. These tools are aimed at bridging the gap between trusted, widely-used radiation analysis codes and very powerful, more recent and commonly used visualization software, thus supporting the design process and helping with shielding optimization. Three main lines of development were followed: mesh-based analysis of Monte Carlo codes, mesh-based analysis of deterministic codes and Monte Carlo surface meshing. The developed kit is considered a powerful and cost-effective tool in the computer-aided design formore » radiation transport code users of the nuclear world, and in particular in the fields of core design and radiation analysis. (authors)« less

Qualitative Data Analysis for Health Services Research: Developing Taxonomy, Themes, and Theory

PubMed Central

Bradley, Elizabeth H; Curry, Leslie A; Devers, Kelly J

2007-01-01

Objective To provide practical strategies for conducting and evaluating analyses of qualitative data applicable for health services researchers. Data Sources and Design We draw on extant qualitative methodological literature to describe practical approaches to qualitative data analysis. Approaches to data analysis vary by discipline and analytic tradition; however, we focus on qualitative data analysis that has as a goal the generation of taxonomy, themes, and theory germane to health services research. Principle Findings We describe an approach to qualitative data analysis that applies the principles of inductive reasoning while also employing predetermined code types to guide data analysis and interpretation. These code types (conceptual, relationship, perspective, participant characteristics, and setting codes) define a structure that is appropriate for generation of taxonomy, themes, and theory. Conceptual codes and subcodes facilitate the development of taxonomies. Relationship and perspective codes facilitate the development of themes and theory. Intersectional analyses with data coded for participant characteristics and setting codes can facilitate comparative analyses. Conclusions Qualitative inquiry can improve the description and explanation of complex, real-world phenomena pertinent to health services research. Greater understanding of the processes of qualitative data analysis can be helpful for health services researchers as they use these methods themselves or collaborate with qualitative researchers from a wide range of disciplines. PMID:17286625

Qualitative data analysis for health services research: developing taxonomy, themes, and theory.

PubMed

Bradley, Elizabeth H; Curry, Leslie A; Devers, Kelly J

2007-08-01

To provide practical strategies for conducting and evaluating analyses of qualitative data applicable for health services researchers. DATA SOURCES AND DESIGN: We draw on extant qualitative methodological literature to describe practical approaches to qualitative data analysis. Approaches to data analysis vary by discipline and analytic tradition; however, we focus on qualitative data analysis that has as a goal the generation of taxonomy, themes, and theory germane to health services research. We describe an approach to qualitative data analysis that applies the principles of inductive reasoning while also employing predetermined code types to guide data analysis and interpretation. These code types (conceptual, relationship, perspective, participant characteristics, and setting codes) define a structure that is appropriate for generation of taxonomy, themes, and theory. Conceptual codes and subcodes facilitate the development of taxonomies. Relationship and perspective codes facilitate the development of themes and theory. Intersectional analyses with data coded for participant characteristics and setting codes can facilitate comparative analyses. Qualitative inquiry can improve the description and explanation of complex, real-world phenomena pertinent to health services research. Greater understanding of the processes of qualitative data analysis can be helpful for health services researchers as they use these methods themselves or collaborate with qualitative researchers from a wide range of disciplines.

Combustion: Structural interaction in a viscoelastic material

NASA Technical Reports Server (NTRS)

Chang, T. Y.; Chang, J. P.; Kumar, M.; Kuo, K. K.

1980-01-01

The effect of interaction between combustion processes and structural deformation of solid propellant was considered. The combustion analysis was performed on the basis of deformed crack geometry, which was determined from the structural analysis. On the other hand, input data for the structural analysis, such as pressure distribution along the crack boundary and ablation velocity of the crack, were determined from the combustion analysis. The interaction analysis was conducted by combining two computer codes, a combustion analysis code and a general purpose finite element structural analysis code.

Development of advanced structural analysis methodologies for predicting widespread fatigue damage in aircraft structures

NASA Technical Reports Server (NTRS)

Harris, Charles E.; Starnes, James H., Jr.; Newman, James C., Jr.

1995-01-01

NASA is developing a 'tool box' that includes a number of advanced structural analysis computer codes which, taken together, represent the comprehensive fracture mechanics capability required to predict the onset of widespread fatigue damage. These structural analysis tools have complementary and specialized capabilities ranging from a finite-element-based stress-analysis code for two- and three-dimensional built-up structures with cracks to a fatigue and fracture analysis code that uses stress-intensity factors and material-property data found in 'look-up' tables or from equations. NASA is conducting critical experiments necessary to verify the predictive capabilities of the codes, and these tests represent a first step in the technology-validation and industry-acceptance processes. NASA has established cooperative programs with aircraft manufacturers to facilitate the comprehensive transfer of this technology by making these advanced structural analysis codes available to industry.

FERRET data analysis code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmittroth, F.

1979-09-01

A documentation of the FERRET data analysis code is given. The code provides a way to combine related measurements and calculations in a consistent evaluation. Basically a very general least-squares code, it is oriented towards problems frequently encountered in nuclear data and reactor physics. A strong emphasis is on the proper treatment of uncertainties and correlations and in providing quantitative uncertainty estimates. Documentation includes a review of the method, structure of the code, input formats, and examples.

Current and anticipated uses of thermalhydraulic and neutronic codes at PSI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aksan, S.N.; Zimmermann, M.A.; Yadigaroglu, G.

1997-07-01

The thermalhydraulic and/or neutronic codes in use at PSI mainly provide the capability to perform deterministic safety analysis for Swiss NPPs and also serve as analysis tools for experimental facilities for LWR and ALWR simulations. In relation to these applications, physical model development and improvements, and assessment of the codes are also essential components of the activities. In this paper, a brief overview is provided on the thermalhydraulic and/or neutronic codes used for safety analysis of LWRs, at PSI, and also of some experiences and applications with these codes. Based on these experiences, additional assessment needs are indicated, together withmore » some model improvement needs. The future needs that could be used to specify both the development of a new code and also improvement of available codes are summarized.« less

Content Analysis Coding Schemes for Online Asynchronous Discussion

ERIC Educational Resources Information Center

Weltzer-Ward, Lisa

2011-01-01

Purpose: Researchers commonly utilize coding-based analysis of classroom asynchronous discussion contributions as part of studies of online learning and instruction. However, this analysis is inconsistent from study to study with over 50 coding schemes and procedures applied in the last eight years. The aim of this article is to provide a basis…

Meanline Analysis of Turbines with Choked Flow in the Object-Oriented Turbomachinery Analysis Code

NASA Technical Reports Server (NTRS)

Hendricks, Eric S.

2016-01-01

The Object-Oriented Turbomachinery Analysis Code (OTAC) is a new meanline/streamline turbomachinery modeling tool being developed at NASA GRC. During the development process, a limitation of the code was discovered in relation to the analysis of choked flow in axial turbines. This paper describes the relevant physics for choked flow as well as the changes made to OTAC to enable analysis in this flow regime.

Analysis of the return to power scenario following a LBLOCA in a PWR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Macian, R.; Tyler, T.N.; Mahaffy, J.H.

1995-09-01

The risk of reactivity accidents has been considered an important safety issue since the beginning of the nuclear power industry. In particular, several events leading to such scenarios for PWR`s have been recognized and studied to assess the potential risk of fuel damage. The present paper analyzes one such event: the possible return to power during the reflooding phase following a LBLOCA. TRAC-PF1/MOD2 coupled with a three-dimensional neutronic model of the core based on the Nodal Expansion Method (NEM) was used to perform the analysis. The system computer model contains a detailed representation of a complete typical 4-loop PWR. Thus,more » the simulation can follow complex system interactions during reflooding, which may influence the neutronics feedback in the core. Analyses were made with core models bases on cross sections generated by LEOPARD. A standard and a potentially more limiting case, with increased pressurizer and accumulator inventories, were run. In both simulations, the reactor reaches a stable state after the reflooding is completed. The lower core region, filled with cold water, generates enough power to boil part of the incoming liquid, thus preventing the core average liquid fraction from reaching a value high enough to cause a return to power. At the same time, the mass flow rate through the core is adequate to maintain the rod temperature well below the fuel damage limit.« less

ASTROP2-LE: A Mistuned Aeroelastic Analysis System Based on a Two Dimensional Linearized Euler Solver

NASA Technical Reports Server (NTRS)

Reddy, T. S. R.; Srivastava, R.; Mehmed, Oral

2002-01-01

An aeroelastic analysis system for flutter and forced response analysis of turbomachines based on a two-dimensional linearized unsteady Euler solver has been developed. The ASTROP2 code, an aeroelastic stability analysis program for turbomachinery, was used as a basis for this development. The ASTROP2 code uses strip theory to couple a two dimensional aerodynamic model with a three dimensional structural model. The code was modified to include forced response capability. The formulation was also modified to include aeroelastic analysis with mistuning. A linearized unsteady Euler solver, LINFLX2D is added to model the unsteady aerodynamics in ASTROP2. By calculating the unsteady aerodynamic loads using LINFLX2D, it is possible to include the effects of transonic flow on flutter and forced response in the analysis. The stability is inferred from an eigenvalue analysis. The revised code, ASTROP2-LE for ASTROP2 code using Linearized Euler aerodynamics, is validated by comparing the predictions with those obtained using linear unsteady aerodynamic solutions.

Guidelines for Coding and Entering Ground-Water Data into the Ground-Water Site Inventory Data Base, Version 4.6, U.S. Geological Survey, Washington Water Science Center

DTIC Science & Technology

2006-01-01

collected, code both. Code Type of Analysis Code Type of Analysis A Physical properties I Common ions/trace elements B Common ions J Sanitary analysis and...1) A ground-water site is coded as if it is a single point, not a geographic area or property . (2) Latitude and longitude should be determined at a...terrace from an adjacent upland on one side, and a lowland coast or valley on the other. Due to the effects of erosion, the terrace surface may not be as

EAC: A program for the error analysis of STAGS results for plates

NASA Technical Reports Server (NTRS)

Sistla, Rajaram; Thurston, Gaylen A.; Bains, Nancy Jane C.

1989-01-01

A computer code is now available for estimating the error in results from the STAGS finite element code for a shell unit consisting of a rectangular orthotropic plate. This memorandum contains basic information about the computer code EAC (Error Analysis and Correction) and describes the connection between the input data for the STAGS shell units and the input data necessary to run the error analysis code. The STAGS code returns a set of nodal displacements and a discrete set of stress resultants; the EAC code returns a continuous solution for displacements and stress resultants. The continuous solution is defined by a set of generalized coordinates computed in EAC. The theory and the assumptions that determine the continuous solution are also outlined in this memorandum. An example of application of the code is presented and instructions on its usage on the Cyber and the VAX machines have been provided.

Development of probabilistic multimedia multipathway computer codes.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yu, C.; LePoire, D.; Gnanapragasam, E.

2002-01-01

The deterministic multimedia dose/risk assessment codes RESRAD and RESRAD-BUILD have been widely used for many years for evaluation of sites contaminated with residual radioactive materials. The RESRAD code applies to the cleanup of sites (soils) and the RESRAD-BUILD code applies to the cleanup of buildings and structures. This work describes the procedure used to enhance the deterministic RESRAD and RESRAD-BUILD codes for probabilistic dose analysis. A six-step procedure was used in developing default parameter distributions and the probabilistic analysis modules. These six steps include (1) listing and categorizing parameters; (2) ranking parameters; (3) developing parameter distributions; (4) testing parameter distributionsmore » for probabilistic analysis; (5) developing probabilistic software modules; and (6) testing probabilistic modules and integrated codes. The procedures used can be applied to the development of other multimedia probabilistic codes. The probabilistic versions of RESRAD and RESRAD-BUILD codes provide tools for studying the uncertainty in dose assessment caused by uncertain input parameters. The parameter distribution data collected in this work can also be applied to other multimedia assessment tasks and multimedia computer codes.« less

Project management web tools at the MICE experiment

NASA Astrophysics Data System (ADS)

Coney, L. R.; Tunnell, C. D.

2012-12-01

Project management tools like Trac are commonly used within the open-source community to coordinate projects. The Muon Ionization Cooling Experiment (MICE) uses the project management web application Redmine to host mice.rl.ac.uk. Many groups within the experiment have a Redmine project: analysis, computing and software (including offline, online, controls and monitoring, and database subgroups), executive board, and operations. All of these groups use the website to communicate, track effort, develop schedules, and maintain documentation. The issue tracker is a rich tool that is used to identify tasks and monitor progress within groups on timescales ranging from immediate and unexpected problems to milestones that cover the life of the experiment. It allows the prioritization of tasks according to time-sensitivity, while providing a searchable record of work that has been done. This record of work can be used to measure both individual and overall group activity, identify areas lacking sufficient personnel or effort, and as a measure of progress against the schedule. Given that MICE, like many particle physics experiments, is an international community, such a system is required to allow easy communication within a global collaboration. Unlike systems that are purely wiki-based, the structure of a project management tool like Redmine allows information to be maintained in a more structured and logical fashion.

Deletion of Adseverin in Osteoclasts Affects Cell Structure But Not Bone Metabolism.

PubMed

Cao, Yixuan; Wang, Yongqiang; Sprangers, Sara; Picavet, Daisy I; Glogauer, Michael; McCulloch, Christopher A; Everts, Vincent

2017-08-01

Adseverin is an actin-severing/capping protein that may contribute to osteoclast differentiation in vitro but its role in bone remodeling of healthy animals is not defined. We analyzed bone and osteoclast structure in adseverin conditional null mice at alveolar and long bone sites. In wild-type and adseverin null mice, as measured by dual-energy X-ray absorptiometry, there were no differences of bone mineral content or bone mineral density, indicating no change of bone metabolism. In tibiae, TRAcP + osteoclasts were formed in comparable numbers in adseverin null and wild-type mice. Ultrastructural analysis showed normal and similar abundance of ruffled borders, sealing zones, and mitochondria, and with no difference of osteoclast nuclear numbers. In contrast, analyses of long bone showed that in the absence of adseverin osteoclasts were smaller (120 ± 13 vs. 274 ± 19 µm 2 ; p < 0.05), as were nuclear size and the surface area of cytoplasm. The nuclei of adseverin null osteoclasts exhibited more heterochromatin (31 ± 3%) than wild-type cells (8 ± 1%), suggesting that adseverin affects cell differentiation. The data indicate that in healthy, developing tissues, adseverin contributes to the regulation of osteoclast structure but not to bone metabolism in vivo.

Energy Savings Analysis of the Proposed NYStretch-Energy Code 2018

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Bing; Zhang, Jian; Chen, Yan

This study was conducted by the Pacific Northwest National Laboratory (PNNL) in support of the stretch energy code development led by the New York State Energy Research and Development Authority (NYSERDA). In 2017 NYSERDA developed its 2016 Stretch Code Supplement to the 2016 New York State Energy Conservation Construction Code (hereinafter referred to as “NYStretch-Energy”). NYStretch-Energy is intended as a model energy code for statewide voluntary adoption that anticipates other code advancements culminating in the goal of a statewide Net Zero Energy Code by 2028. Since then, NYSERDA continues to develop the NYStretch-Energy Code 2018 edition. To support the effort,more » PNNL conducted energy simulation analysis to quantify the energy savings of proposed commercial provisions of the NYStretch-Energy Code (2018) in New York. The focus of this project is the 20% improvement over existing commercial model energy codes. A key requirement of the proposed stretch code is that it be ‘adoptable’ as an energy code, meaning that it must align with current code scope and limitations, and primarily impact building components that are currently regulated by local building departments. It is largely limited to prescriptive measures, which are what most building departments and design projects are most familiar with. This report describes a set of energy-efficiency measures (EEMs) that demonstrate 20% energy savings over ANSI/ASHRAE/IES Standard 90.1-2013 (ASHRAE 2013) across a broad range of commercial building types and all three climate zones in New York. In collaboration with New Building Institute, the EEMs were developed from national model codes and standards, high-performance building codes and standards, regional energy codes, and measures being proposed as part of the on-going code development process. PNNL analyzed these measures using whole building energy models for selected prototype commercial buildings and multifamily buildings representing buildings in New York. Section 2 of this report describes the analysis methodology, including the building types and construction area weights update for this analysis, the baseline, and the method to conduct the energy saving analysis. Section 3 provides detailed specifications of the EEMs and bundles. Section 4 summarizes the results of individual EEMs and EEM bundles by building type, energy end-use and climate zone. Appendix A documents detailed descriptions of the selected prototype buildings. Appendix B provides energy end-use breakdown results by building type for both the baseline code and stretch code in all climate zones.« less

New technologies for advanced three-dimensional optimum shape design in aeronautics

NASA Astrophysics Data System (ADS)

Dervieux, Alain; Lanteri, Stéphane; Malé, Jean-Michel; Marco, Nathalie; Rostaing-Schmidt, Nicole; Stoufflet, Bruno

1999-05-01

The analysis of complex flows around realistic aircraft geometries is becoming more and more predictive. In order to obtain this result, the complexity of flow analysis codes has been constantly increasing, involving more refined fluid models and sophisticated numerical methods. These codes can only run on top computers, exhausting their memory and CPU capabilities. It is, therefore, difficult to introduce best analysis codes in a shape optimization loop: most previous works in the optimum shape design field used only simplified analysis codes. Moreover, as the most popular optimization methods are the gradient-based ones, the more complex the flow solver, the more difficult it is to compute the sensitivity code. However, emerging technologies are contributing to make such an ambitious project, of including a state-of-the-art flow analysis code into an optimisation loop, feasible. Among those technologies, there are three important issues that this paper wishes to address: shape parametrization, automated differentiation and parallel computing. Shape parametrization allows faster optimization by reducing the number of design variable; in this work, it relies on a hierarchical multilevel approach. The sensitivity code can be obtained using automated differentiation. The automated approach is based on software manipulation tools, which allow the differentiation to be quick and the resulting differentiated code to be rather fast and reliable. In addition, the parallel algorithms implemented in this work allow the resulting optimization software to run on increasingly larger geometries. Copyright

Intrasystem Analysis Program (IAP) code summaries

NASA Astrophysics Data System (ADS)

Dobmeier, J. J.; Drozd, A. L. S.; Surace, J. A.

1983-05-01

This report contains detailed descriptions and capabilities of the codes that comprise the Intrasystem Analysis Program. The four codes are: Intrasystem Electromagnetic Compatibility Analysis Program (IEMCAP), General Electromagnetic Model for the Analysis of Complex Systems (GEMACS), Nonlinear Circuit Analysis Program (NCAP), and Wire Coupling Prediction Models (WIRE). IEMCAP is used for computer-aided evaluation of electromagnetic compatibility (ECM) at all stages of an Air Force system's life cycle, applicable to aircraft, space/missile, and ground-based systems. GEMACS utilizes a Method of Moments (MOM) formalism with the Electric Field Integral Equation (EFIE) for the solution of electromagnetic radiation and scattering problems. The code employs both full matrix decomposition and Banded Matrix Iteration solution techniques and is expressly designed for large problems. NCAP is a circuit analysis code which uses the Volterra approach to solve for the transfer functions and node voltage of weakly nonlinear circuits. The Wire Programs deal with the Application of Multiconductor Transmission Line Theory to the Prediction of Cable Coupling for specific classes of problems.

Industrial Code Development

NASA Technical Reports Server (NTRS)

Shapiro, Wilbur

1991-01-01

The industrial codes will consist of modules of 2-D and simplified 2-D or 1-D codes, intended for expeditious parametric studies, analysis, and design of a wide variety of seals. Integration into a unified system is accomplished by the industrial Knowledge Based System (KBS), which will also provide user friendly interaction, contact sensitive and hypertext help, design guidance, and an expandable database. The types of analysis to be included with the industrial codes are interfacial performance (leakage, load, stiffness, friction losses, etc.), thermoelastic distortions, and dynamic response to rotor excursions. The first three codes to be completed and which are presently being incorporated into the KBS are the incompressible cylindrical code, ICYL, and the compressible cylindrical code, GCYL.

The Secure Medical Research Workspace: An IT Infrastructure to Enable Secure Research on Clinical Data

PubMed Central

Owen, Phillips; Mostafa, Javed; Lamm, Brent; Wang, Xiaoshu; Schmitt, Charles P.; Ahalt, Stanley C.

2013-01-01

Abstract Clinical data have tremendous value for translational research, but only if security and privacy concerns can be addressed satisfactorily. A collaboration of clinical and informatics teams, including RENCI, NC TraCS, UNC's School of Information and Library Science, Information Technology Service's Research Computing and other partners at the University of North Carolina at Chapel Hill have developed a system called the Secure Medical Research Workspace (SMRW) that enables researchers to use clinical data securely for research. SMRW significantly minimizes the risk presented when using identified clinical data, thereby protecting patients, researchers, and institutions associated with the data. The SMRW is built on a novel combination of virtualization and data leakage protection and can be combined with other protection methodologies and scaled to production levels. PMID:23751029

Automation of the targeting and reflective alignment concept

NASA Technical Reports Server (NTRS)

Redfield, Robin C.

1992-01-01

The automated alignment system, described herein, employs a reflective, passive (requiring no power) target and includes a PC-based imaging system and one camera mounted on a six degree of freedom robot manipulator. The system detects and corrects for manipulator misalignment in three translational and three rotational directions by employing the Targeting and Reflective Alignment Concept (TRAC), which simplifies alignment by decoupling translational and rotational alignment control. The concept uses information on the camera and the target's relative position based on video feedback from the camera. These relative positions are converted into alignment errors and minimized by motions of the robot. The system is robust to exogenous lighting by virtue of a subtraction algorithm which enables the camera to only see the target. These capabilities are realized with relatively minimal complexity and expense.

Networking consumer health information: bringing the patient into the medical information loop.

PubMed

Martin, E R; Lanier, D

1996-04-01

The Library of the Health Sciences at the University of Illinois at Chicago obtained a grant from the Illinois State Library to implement a statewide demonstration project that would provide consumer health information (CHI) using InfoTrac's Health Reference Center CD-ROM database. The goals of the project were to cooperate with targeted public libraries and clinics in providing CHI at the earliest point of need; to provide access to the database via a dial-up network server and a toll-free telephone number; and to work with targeted sites on database training, core CHI reference sources, and referral procedures. This paper provides background information about the project; describes the major systems and technical issues encountered; and discusses the outcomes, impact, and envisioned enhancements.

The STAGS computer code

NASA Technical Reports Server (NTRS)

Almroth, B. O.; Brogan, F. A.

1978-01-01

Basic information about the computer code STAGS (Structural Analysis of General Shells) is presented to describe to potential users the scope of the code and the solution procedures that are incorporated. Primarily, STAGS is intended for analysis of shell structures, although it has been extended to more complex shell configurations through the inclusion of springs and beam elements. The formulation is based on a variational approach in combination with local two dimensional power series representations of the displacement components. The computer code includes options for analysis of linear or nonlinear static stress, stability, vibrations, and transient response. Material as well as geometric nonlinearities are included. A few examples of applications of the code are presented for further illustration of its scope.

Code Analysis and Refactoring with Clang Tools, Version 0.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kelley, Timothy M.

2016-12-23

Code Analysis and Refactoring with Clang Tools is a small set of example code that demonstrates techniques for applying tools distributed with the open source Clang compiler. Examples include analyzing where variables are used and replacing old data structures with standard structures.

Hypercube matrix computation task

NASA Technical Reports Server (NTRS)

Calalo, Ruel H.; Imbriale, William A.; Jacobi, Nathan; Liewer, Paulett C.; Lockhart, Thomas G.; Lyzenga, Gregory A.; Lyons, James R.; Manshadi, Farzin; Patterson, Jean E.

1988-01-01

A major objective of the Hypercube Matrix Computation effort at the Jet Propulsion Laboratory (JPL) is to investigate the applicability of a parallel computing architecture to the solution of large-scale electromagnetic scattering problems. Three scattering analysis codes are being implemented and assessed on a JPL/California Institute of Technology (Caltech) Mark 3 Hypercube. The codes, which utilize different underlying algorithms, give a means of evaluating the general applicability of this parallel architecture. The three analysis codes being implemented are a frequency domain method of moments code, a time domain finite difference code, and a frequency domain finite elements code. These analysis capabilities are being integrated into an electromagnetics interactive analysis workstation which can serve as a design tool for the construction of antennas and other radiating or scattering structures. The first two years of work on the Hypercube Matrix Computation effort is summarized. It includes both new developments and results as well as work previously reported in the Hypercube Matrix Computation Task: Final Report for 1986 to 1987 (JPL Publication 87-18).

Evaluation of the DRAGON code for VHTR design analysis.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taiwo, T. A.; Kim, T. K.; Nuclear Engineering Division

2006-01-12

This letter report summarizes three activities that were undertaken in FY 2005 to gather information on the DRAGON code and to perform limited evaluations of the code performance when used in the analysis of the Very High Temperature Reactor (VHTR) designs. These activities include: (1) Use of the code to model the fuel elements of the helium-cooled and liquid-salt-cooled VHTR designs. Results were compared to those from another deterministic lattice code (WIMS8) and a Monte Carlo code (MCNP). (2) The preliminary assessment of the nuclear data library currently used with the code and libraries that have been provided by themore » IAEA WIMS-D4 Library Update Project (WLUP). (3) DRAGON workshop held to discuss the code capabilities for modeling the VHTR.« less

A Bayesian network coding scheme for annotating biomedical information presented to genetic counseling clients.

PubMed

Green, Nancy

2005-04-01

We developed a Bayesian network coding scheme for annotating biomedical content in layperson-oriented clinical genetics documents. The coding scheme supports the representation of probabilistic and causal relationships among concepts in this domain, at a high enough level of abstraction to capture commonalities among genetic processes and their relationship to health. We are using the coding scheme to annotate a corpus of genetic counseling patient letters as part of the requirements analysis and knowledge acquisition phase of a natural language generation project. This paper describes the coding scheme and presents an evaluation of intercoder reliability for its tag set. In addition to giving examples of use of the coding scheme for analysis of discourse and linguistic features in this genre, we suggest other uses for it in analysis of layperson-oriented text and dialogue in medical communication.

Sports Stars: Analyzing the Performance of Astronomers at Visualization-based Discovery

NASA Astrophysics Data System (ADS)

Fluke, C. J.; Parrington, L.; Hegarty, S.; MacMahon, C.; Morgan, S.; Hassan, A. H.; Kilborn, V. A.

2017-05-01

In this data-rich era of astronomy, there is a growing reliance on automated techniques to discover new knowledge. The role of the astronomer may change from being a discoverer to being a confirmer. But what do astronomers actually look at when they distinguish between “sources” and “noise?” What are the differences between novice and expert astronomers when it comes to visual-based discovery? Can we identify elite talent or coach astronomers to maximize their potential for discovery? By looking to the field of sports performance analysis, we consider an established, domain-wide approach, where the expertise of the viewer (i.e., a member of the coaching team) plays a crucial role in identifying and determining the subtle features of gameplay that provide a winning advantage. As an initial case study, we investigate whether the SportsCode performance analysis software can be used to understand and document how an experienced Hi astronomer makes discoveries in spectral data cubes. We find that the process of timeline-based coding can be applied to spectral cube data by mapping spectral channels to frames within a movie. SportsCode provides a range of easy to use methods for annotation, including feature-based codes and labels, text annotations associated with codes, and image-based drawing. The outputs, including instance movies that are uniquely associated with coded events, provide the basis for a training program or team-based analysis that could be used in unison with discipline specific analysis software. In this coordinated approach to visualization and analysis, SportsCode can act as a visual notebook, recording the insight and decisions in partnership with established analysis methods. Alternatively, in situ annotation and coding of features would be a valuable addition to existing and future visualization and analysis packages.

A structured training programme for caregivers of inpatients after stroke (TRACS): a cluster randomised controlled trial and cost-effectiveness analysis.

PubMed

Forster, Anne; Dickerson, Josie; Young, John; Patel, Anita; Kalra, Lalit; Nixon, Jane; Smithard, David; Knapp, Martin; Holloway, Ivana; Anwar, Shamaila; Farrin, Amanda

2013-12-21

Most patients who have had a stroke are dependent on informal caregivers for activities of daily living. The TRACS trial investigated a training programme for caregivers (the London Stroke Carers Training Course, LSCTC) on physical and psychological outcomes, including cost-effectiveness, for patients and caregivers after a disabling stroke. We undertook a pragmatic, multicentre, cluster randomised controlled trial with a parallel cost-effectiveness analysis. Stroke units were eligible if four of five criteria used to define a stroke unit were met, a substantial number of patients on the unit had a diagnosis of stroke, staff were able to deliver the LSCTC, and most patients were discharged to a permanent place of residence. Stroke units were randomly assigned to either LSCTC or usual care (control group), stratified by geographical region and quality of care, and using blocks of size 2. Patients with a diagnosis of stroke, likely to return home with residual disability and with a caregiver providing support were eligible. The primary outcome for patients was self-reported extended activities of daily living at 6 months, measured with the Nottingham Extended Activities of Daily Living (NEADL) scale. The primary outcome for caregivers was self-reported burden at 6 months, measured with the caregivers burden scale (CBS). We combined patient and caregiver costs with primary outcomes and quality-adjusted life-years (QALYs) to assess cost-effectiveness. This trial is registered with controlled-trials.com, number ISRCTN 49208824. We assessed 49 stroke units for eligibility, of which 36 were randomly assigned to either the intervention group or the control group. Between Feb 27, 2008, and Feb 9, 2010, 928 patient and caregiver dyads were registered, of which 450 were in the intervention group, and 478 in the control group. Patients' self-reported extended activities of daily living did not differ between groups at 6 months (adjusted mean NEADL score 27·4 in the intervention group versus 27·6 in the control group, difference -0·2 points [95% CI -3·0 to 2·5], p value=0·866, ICC=0·027). The caregiver burden scale did not differ between groups either (adjusted mean CBS 45·5 in the intervention group versus 45·0 in the control group, difference 0·5 points [95% CI -1·7 to 2·7], p value=0·660, ICC=0·013). Patient and caregiver costs were similar in both groups (length of the initial stroke admission and associated costs were £13,127 for the intervention group and £12,471 for the control group; adjusted mean difference £1243 [95% CI -1533 to 4019]; p value=0·380). Probabilities of cost-effectiveness based on QALYs were low. In a large scale, robust evaluation, results from this study have shown no differences between the LSCTC and usual care on any of the assessed outcomes. The immediate period after stroke might not be the ideal time to deliver structured caregiver training. Medical Research Council. Copyright © 2013 Elsevier Ltd. All rights reserved.

Mal-Xtract: Hidden Code Extraction using Memory Analysis

NASA Astrophysics Data System (ADS)

Lim, Charles; Syailendra Kotualubun, Yohanes; Suryadi; Ramli, Kalamullah

2017-01-01

Software packer has been used effectively to hide the original code inside a binary executable, making it more difficult for existing signature based anti malware software to detect malicious code inside the executable. A new method of written and rewritten memory section is introduced to to detect the exact end time of unpacking routine and extract original code from packed binary executable using Memory Analysis running in an software emulated environment. Our experiment results show that at least 97% of the original code from the various binary executable packed with different software packers could be extracted. The proposed method has also been successfully extracted hidden code from recent malware family samples.

Interactive Finite Elements for General Engine Dynamics Analysis

NASA Technical Reports Server (NTRS)

Adams, M. L.; Padovan, J.; Fertis, D. G.

1984-01-01

General nonlinear finite element codes were adapted for the purpose of analyzing the dynamics of gas turbine engines. In particular, this adaptation required the development of a squeeze-film damper element software package and its implantation into a representative current generation code. The ADINA code was selected because of prior use of it and familiarity with its internal structure and logic. This objective was met and the results indicate that such use of general purpose codes is viable alternative to specialized codes for general dynamics analysis of engines.

Development of an integrated thermal-hydraulics capability incorporating RELAP5 and PANTHER neutronics code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Page, R.; Jones, J.R.

1997-07-01

Ensuring that safety analysis needs are met in the future is likely to lead to the development of new codes and the further development of existing codes. It is therefore advantageous to define standards for data interfaces and to develop software interfacing techniques which can readily accommodate changes when they are made. Defining interface standards is beneficial but is necessarily restricted in application if future requirements are not known in detail. Code interfacing methods are of particular relevance with the move towards automatic grid frequency response operation where the integration of plant dynamic, core follow and fault study calculation toolsmore » is considered advantageous. This paper describes the background and features of a new code TALINK (Transient Analysis code LINKage program) used to provide a flexible interface to link the RELAP5 thermal hydraulics code with the PANTHER neutron kinetics and the SIBDYM whole plant dynamic modelling codes used by Nuclear Electric. The complete package enables the codes to be executed in parallel and provides an integrated whole plant thermal-hydraulics and neutron kinetics model. In addition the paper discusses the capabilities and pedigree of the component codes used to form the integrated transient analysis package and the details of the calculation of a postulated Sizewell `B` Loss of offsite power fault transient.« less

Error control techniques for satellite and space communications

NASA Technical Reports Server (NTRS)

Costello, Daniel J., Jr.

1988-01-01

During the period December 1, 1987 through May 31, 1988, progress was made in the following areas: construction of Multi-Dimensional Bandwidth Efficient Trellis Codes with MPSK modulation; performance analysis of Bandwidth Efficient Trellis Coded Modulation schemes; and performance analysis of Bandwidth Efficient Trellis Codes on Fading Channels.

Modeling of rolling element bearing mechanics. Computer program user's manual

NASA Technical Reports Server (NTRS)

Greenhill, Lyn M.; Merchant, David H.

1994-01-01

This report provides the user's manual for the Rolling Element Bearing Analysis System (REBANS) analysis code which determines the quasistatic response to external loads or displacement of three types of high-speed rolling element bearings: angular contact ball bearings, duplex angular contact ball bearings, and cylindrical roller bearings. The model includes the defects of bearing ring and support structure flexibility. It is comprised of two main programs: the Preprocessor for Bearing Analysis (PREBAN) which creates the input files for the main analysis program, and Flexibility Enhanced Rolling Element Bearing Analysis (FEREBA), the main analysis program. This report addresses input instructions for and features of the computer codes. A companion report addresses the theoretical basis for the computer codes. REBANS extends the capabilities of the SHABERTH (Shaft and Bearing Thermal Analysis) code to include race and housing flexibility, including such effects as dead band and preload springs.

Sandia Engineering Analysis Code Access System v. 2.0.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjaardema, Gregory D.

The Sandia Engineering Analysis Code Access System (SEACAS) is a suite of preprocessing, post processing, translation, visualization, and utility applications supporting finite element analysis software using the Exodus database file format.

FEAMAC-CARES Software Coupling Development Effort for CMC Stochastic-Strength-Based Damage Simulation

NASA Technical Reports Server (NTRS)

Nemeth, Noel N.; Bednarcyk, Brett A.; Pineda, Evan; Arnold, Steven; Mital, Subodh; Murthy, Pappu; Walton, Owen

2015-01-01

Reported here is a coupling of two NASA developed codes: CARES (Ceramics Analysis and Reliability Evaluation of Structures) with the MACGMC composite material analysis code. The resulting code is called FEAMACCARES and is constructed as an Abaqus finite element analysis UMAT (user defined material). Here we describe the FEAMACCARES code and an example problem (taken from the open literature) of a laminated CMC in off-axis loading is shown. FEAMACCARES performs stochastic-strength-based damage simulation response of a CMC under multiaxial loading using elastic stiffness reduction of the failed elements.

Local Laplacian Coding From Theoretical Analysis of Local Coding Schemes for Locally Linear Classification.

PubMed

Pang, Junbiao; Qin, Lei; Zhang, Chunjie; Zhang, Weigang; Huang, Qingming; Yin, Baocai

2015-12-01

Local coordinate coding (LCC) is a framework to approximate a Lipschitz smooth function by combining linear functions into a nonlinear one. For locally linear classification, LCC requires a coding scheme that heavily determines the nonlinear approximation ability, posing two main challenges: 1) the locality making faraway anchors have smaller influences on current data and 2) the flexibility balancing well between the reconstruction of current data and the locality. In this paper, we address the problem from the theoretical analysis of the simplest local coding schemes, i.e., local Gaussian coding and local student coding, and propose local Laplacian coding (LPC) to achieve the locality and the flexibility. We apply LPC into locally linear classifiers to solve diverse classification tasks. The comparable or exceeded performances of state-of-the-art methods demonstrate the effectiveness of the proposed method.

Superimposed Code Theoretic Analysis of DNA Codes and DNA Computing

DTIC Science & Technology

2008-01-01

complements of one another and the DNA duplex formed is a Watson - Crick (WC) duplex. However, there are many instances when the formation of non-WC...that the user’s requirements for probe selection are met based on the Watson - Crick probe locality within a target. The second type, called...AFRL-RI-RS-TR-2007-288 Final Technical Report January 2008 SUPERIMPOSED CODE THEORETIC ANALYSIS OF DNA CODES AND DNA COMPUTING

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uchibori, Akihiro; Kurihara, Akikazu; Ohshima, Hiroyuki

A multiphysics analysis system for sodium-water reaction phenomena in a steam generator of sodium-cooled fast reactors was newly developed. The analysis system consists of the mechanistic numerical analysis codes, SERAPHIM, TACT, and RELAP5. The SERAPHIM code calculates the multicomponent multiphase flow and sodium-water chemical reaction caused by discharging of pressurized water vapor. Applicability of the SERAPHIM code was confirmed through the analyses of the experiment on water vapor discharging in liquid sodium. The TACT code was developed to calculate heat transfer from the reacting jet to the adjacent tube and to predict the tube failure occurrence. The numerical models integratedmore » into the TACT code were verified through some related experiments. The RELAP5 code evaluates thermal hydraulic behavior of water inside the tube. The original heat transfer correlations were corrected for the tube rapidly heated by the reacting jet. The developed system enables evaluation of the wastage environment and the possibility of the failure propagation.« less

Development and validation of PediaTrac™: A web-based tool to track developing infants.

PubMed

Lajiness-O'Neill, Renée; Brooks, Judith; Lukomski, Angela; Schilling, Stephen; Huth-Bocks, Alissa; Warschausky, Seth; Flores, Ana-Mercedes; Swick, Casey; Nyman, Tristin; Andersen, Tiffany; Morris, Natalie; Schmitt, Thomas A; Bell-Smith, Jennifer; Moir, Barbara; Hodges, Elise K; Lyddy, James E

2018-02-01

PediaTrac™, a 363-item web-based tool to track infant development, administered in modules of ∼40-items per sampling period, newborn (NB), 2--, 4--, 6--, 9-- and 12--months was validated. Caregivers answered demographic, medical, and environmental questions, and questions covering the sensorimotor, feeding/eating, sleep, speech/language, cognition, social-emotional, and attachment domains. Expert Panel Reviews and Cognitive Interviews (CI) were conducted to validate the item bank. Classical Test Theory (CTT) and Item Response Theory (IRT) methods were employed to examine the dimensionality and psychometric properties of PediaTrac with pooled longitudinal and cross-sectional cohorts (N = 132). Intraclass correlation coefficients (ICC) for the Expert Panel Review revealed moderate agreement at 6 -months and good reliability at other sampling periods. ICC estimates for CI revealed moderate reliability regarding clarity of the items at NB and 4 months, good reliability at 2--, 9-- and 12--months and excellent reliability at 6 -months. CTT revealed good coefficient alpha estimates (α ≥ 0.77 for five of the six ages) for the Social-Emotional/Communication, Attachment (α ≥ 0.89 for all ages), and Sensorimotor (α ≥ 0.75 at 6-months) domains, revealing the need for better targeting of sensorimotor items. IRT modeling revealed good reliability (r = 0.85-0.95) for three distinct domains (Feeding/Eating, Social-Emotional/Communication and Attachment) and four subdomains (Feeding Breast/Formula, Feeding Solid Food, Social-Emotional Information Processing, Communication/Cognition). Convergent and discriminant construct validity were demonstrated between our IRT-modeled domains and constructs derived from existing developmental, behavioral and caregiver measures. Our Attachment domain was significantly correlated with existing measures at the NB and 2-month periods, while the Social-Emotional/Communication domain was highly correlated with similar constructs at the 6-, 9- and 12-month periods. PediaTrac has potential for producing novel and effective estimates of infant development via the Sensorimotor, Feeding/Eating, Social-Emotional/Communication and Attachment domains. Copyright © 2018 Elsevier Inc. All rights reserved.

ExacTrac Snap Verification: A New Tool for Ensuring Quality Control for Lung Stereotactic Body Radiation Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Udrescu, Corina; Mornex, Francoise, E-mail: francoise.mornex@chu-lyon.fr; Tanguy, Ronan

2013-01-01

Purpose: The intrafraction verification provided by ExacTrac X-ray 6D Snap Verification (ET-SV) allows the tracking of potential isocenter displacements throughout patient position and treatment. The aims of this study were (1) to measure the intrafraction variations of the isocenter position (random errors); (2) to study the amplitude of the variation related to the fraction duration; and (3) to assess the impact of the table movement on positioning uncertainties. Methods and Materials: ET-SV uses images acquired before or during treatment delivery or both to detect isocenter displacement. Twenty patients treated with stereotactic body radiation therapy (SBRT) for lung tumors underwent SVmore » before or during each beam. Noncoplanar beams were sometimes necessary. The time between the setup of the patient and each SV was noted, and values of deviations were compiled for 3 SV time groups: SV performed at {<=}10 min (group 1), between 11 and 20 min (group 2), and {>=}21 min (group 3). Random errors in positioning during the use of noncoplanar fields were noted. Results: The mean isocenter deviation {+-}SD was 2 {+-} 0.5 mm (range, 1-8 mm). The average deviations {+-}SD increased significantly from 1.6 {+-} 0.5 mm to 2.1 {+-} 0.8 mm and 2.2 {+-} 0.6 mm for groups 1, 2, and 3 (P=.002), respectively. Percentages of deviation {>=}3 mm were 7.06%, 22.83%, and 28.07% and 1.08%, 4.15%, and 8.4% for {>=}5 mm (P<.0001). For 11 patients, table rotation was necessary. The mean isocenter deviation {+-}SD increased significantly from 1.9 {+-} 0.5 mm before table rotation to 2.7 {+-} 0.5 mm (P=.001) for the first beam treated after rotation. Conclusions: SV detects isocenter deviations, which increase in amplitude and frequency with the fraction duration, and enables intrafraction verification for SBRT (taking into account clinical condition and technical issues). SV gives accurate targeting at any time during irradiation and may raise confidence to escalate the dose. SV appears to be an important tool for ensuring the quality control of SBRT.« less

Improvements to a method for the geometrically nonlinear analysis of compressively loaded stiffened composite panels

NASA Technical Reports Server (NTRS)

Stoll, Frederick

1993-01-01

The NLPAN computer code uses a finite-strip approach to the analysis of thin-walled prismatic composite structures such as stiffened panels. The code can model in-plane axial loading, transverse pressure loading, and constant through-the-thickness thermal loading, and can account for shape imperfections. The NLPAN code represents an attempt to extend the buckling analysis of the VIPASA computer code into the geometrically nonlinear regime. Buckling mode shapes generated using VIPASA are used in NLPAN as global functions for representing displacements in the nonlinear regime. While the NLPAN analysis is approximate in nature, it is computationally economical in comparison with finite-element analysis, and is thus suitable for use in preliminary design and design optimization. A comprehensive description of the theoretical approach of NLPAN is provided. A discussion of some operational considerations for the NLPAN code is included. NLPAN is applied to several test problems in order to demonstrate new program capabilities, and to assess the accuracy of the code in modeling various types of loading and response. User instructions for the NLPAN computer program are provided, including a detailed description of the input requirements and example input files for two stiffened-panel configurations.

CRITICA: coding region identification tool invoking comparative analysis

NASA Technical Reports Server (NTRS)

Badger, J. H.; Olsen, G. J.; Woese, C. R. (Principal Investigator)

1999-01-01

Gene recognition is essential to understanding existing and future DNA sequence data. CRITICA (Coding Region Identification Tool Invoking Comparative Analysis) is a suite of programs for identifying likely protein-coding sequences in DNA by combining comparative analysis of DNA sequences with more common noncomparative methods. In the comparative component of the analysis, regions of DNA are aligned with related sequences from the DNA databases; if the translation of the aligned sequences has greater amino acid identity than expected for the observed percentage nucleotide identity, this is interpreted as evidence for coding. CRITICA also incorporates noncomparative information derived from the relative frequencies of hexanucleotides in coding frames versus other contexts (i.e., dicodon bias). The dicodon usage information is derived by iterative analysis of the data, such that CRITICA is not dependent on the existence or accuracy of coding sequence annotations in the databases. This independence makes the method particularly well suited for the analysis of novel genomes. CRITICA was tested by analyzing the available Salmonella typhimurium DNA sequences. Its predictions were compared with the DNA sequence annotations and with the predictions of GenMark. CRITICA proved to be more accurate than GenMark, and moreover, many of its predictions that would seem to be errors instead reflect problems in the sequence databases. The source code of CRITICA is freely available by anonymous FTP (rdp.life.uiuc.edu in/pub/critica) and on the World Wide Web (http:/(/)rdpwww.life.uiuc.edu).

Verification of a Viscous Computational Aeroacoustics Code using External Verification Analysis

NASA Technical Reports Server (NTRS)

Ingraham, Daniel; Hixon, Ray

2015-01-01

The External Verification Analysis approach to code verification is extended to solve the three-dimensional Navier-Stokes equations with constant properties, and is used to verify a high-order computational aeroacoustics (CAA) code. After a brief review of the relevant literature, the details of the EVA approach are presented and compared to the similar Method of Manufactured Solutions (MMS). Pseudocode representations of EVA's algorithms are included, along with the recurrence relations needed to construct the EVA solution. The code verification results show that EVA was able to convincingly verify a high-order, viscous CAA code without the addition of MMS-style source terms, or any other modifications to the code.

Verification of a Viscous Computational Aeroacoustics Code Using External Verification Analysis

NASA Technical Reports Server (NTRS)

Ingraham, Daniel; Hixon, Ray

2015-01-01

The External Verification Analysis approach to code verification is extended to solve the three-dimensional Navier-Stokes equations with constant properties, and is used to verify a high-order computational aeroacoustics (CAA) code. After a brief review of the relevant literature, the details of the EVA approach are presented and compared to the similar Method of Manufactured Solutions (MMS). Pseudocode representations of EVA's algorithms are included, along with the recurrence relations needed to construct the EVA solution. The code verification results show that EVA was able to convincingly verify a high-order, viscous CAA code without the addition of MMS-style source terms, or any other modifications to the code.

Dependency graph for code analysis on emerging architectures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shashkov, Mikhail Jurievich; Lipnikov, Konstantin

Direct acyclic dependency (DAG) graph is becoming the standard for modern multi-physics codes.The ideal DAG is the true block-scheme of a multi-physics code. Therefore, it is the convenient object for insitu analysis of the cost of computations and algorithmic bottlenecks related to statistical frequent data motion and dymanical machine state.

Automatic Coding of Dialogue Acts in Collaboration Protocols

ERIC Educational Resources Information Center

Erkens, Gijsbert; Janssen, Jeroen

2008-01-01

Although protocol analysis can be an important tool for researchers to investigate the process of collaboration and communication, the use of this method of analysis can be time consuming. Hence, an automatic coding procedure for coding dialogue acts was developed. This procedure helps to determine the communicative function of messages in online…

Convergence acceleration of the Proteus computer code with multigrid methods

NASA Technical Reports Server (NTRS)

Demuren, A. O.; Ibraheem, S. O.

1992-01-01

Presented here is the first part of a study to implement convergence acceleration techniques based on the multigrid concept in the Proteus computer code. A review is given of previous studies on the implementation of multigrid methods in computer codes for compressible flow analysis. Also presented is a detailed stability analysis of upwind and central-difference based numerical schemes for solving the Euler and Navier-Stokes equations. Results are given of a convergence study of the Proteus code on computational grids of different sizes. The results presented here form the foundation for the implementation of multigrid methods in the Proteus code.

Finite element analysis of inviscid subsonic boattail flow

NASA Technical Reports Server (NTRS)

Chima, R. V.; Gerhart, P. M.

1981-01-01

A finite element code for analysis of inviscid subsonic flows over arbitrary nonlifting planar or axisymmetric bodies is described. The code solves a novel primitive variable formulation of the coupled irrotationality and compressible continuity equations. Results for flow over a cylinder, a sphere, and a NACA 0012 airfoil verify the code. Computed subcritical flows over an axisymmetric boattailed afterbody compare well with finite difference results and experimental data. Interative coupling with an integral turbulent boundary layer code shows strong viscous effects on the inviscid flow. Improvements in code efficiency and extensions to transonic flows are discussed.

PASCO: Structural panel analysis and sizing code: Users manual - Revised

NASA Technical Reports Server (NTRS)

Anderson, M. S.; Stroud, W. J.; Durling, B. J.; Hennessy, K. W.

1981-01-01

A computer code denoted PASCO is described for analyzing and sizing uniaxially stiffened composite panels. Buckling and vibration analyses are carried out with a linked plate analysis computer code denoted VIPASA, which is included in PASCO. Sizing is based on nonlinear mathematical programming techniques and employs a computer code denoted CONMIN, also included in PASCO. Design requirements considered are initial buckling, material strength, stiffness and vibration frequency. A user's manual for PASCO is presented.

Identification of novel mRNAs and lncRNAs associated with mouse experimental colitis and human inflammatory bowel disease.

PubMed

Rankin, Carl Robert; Theodorou, Evangelos; Law, Ivy Ka Man; Rowe, Lorraine; Kokkotou, Efi; Pekow, Joel; Wang, Jiafang; Martin, Martin G; Pothoulakis, Charalabos; Padua, David Miguel

2018-06-28

Inflammatory bowel disease (IBD) is a complex disorder that is associated with significant morbidity. While many recent advances have been made with new diagnostic and therapeutic tools, a deeper understanding of its basic pathophysiology is needed to continue this trend towards improving treatments. By utilizing an unbiased, high-throughput transcriptomic analysis of two well-established mouse models of colitis, we set out to uncover novel coding and non-coding RNAs that are differentially expressed in the setting of colonic inflammation. RNA-seq analysis was performed using colonic tissue from two mouse models of colitis, a dextran sodium sulfate induced model and a genetic-induced model in mice lacking IL-10. We identified 81 coding RNAs that were commonly altered in both experimental models. Of these coding RNAs, 12 of the human orthologs were differentially expressed in a transcriptomic analysis of IBD patients. Interestingly, 5 of the 12 of human differentially expressed genes have not been previously identified as IBD-associated genes, including ubiquitin D. Our analysis also identified 15 non-coding RNAs that were differentially expressed in either mouse model. Surprisingly, only three non-coding RNAs were commonly dysregulated in both of these models. The discovery of these new coding and non-coding RNAs expands our transcriptional knowledge of mouse models of IBD and offers additional targets to deepen our understanding of the pathophysiology of IBD.

A CFD/CSD Interaction Methodology for Aircraft Wings

NASA Technical Reports Server (NTRS)

Bhardwaj, Manoj K.

1997-01-01

With advanced subsonic transports and military aircraft operating in the transonic regime, it is becoming important to determine the effects of the coupling between aerodynamic loads and elastic forces. Since aeroelastic effects can contribute significantly to the design of these aircraft, there is a strong need in the aerospace industry to predict these aero-structure interactions computationally. To perform static aeroelastic analysis in the transonic regime, high fidelity computational fluid dynamics (CFD) analysis tools must be used in conjunction with high fidelity computational structural fluid dynamics (CSD) analysis tools due to the nonlinear behavior of the aerodynamics in the transonic regime. There is also a need to be able to use a wide variety of CFD and CSD tools to predict these aeroelastic effects in the transonic regime. Because source codes are not always available, it is necessary to couple the CFD and CSD codes without alteration of the source codes. In this study, an aeroelastic coupling procedure is developed which will perform static aeroelastic analysis using any CFD and CSD code with little code integration. The aeroelastic coupling procedure is demonstrated on an F/A-18 Stabilator using NASTD (an in-house McDonnell Douglas CFD code) and NASTRAN. In addition, the Aeroelastic Research Wing (ARW-2) is used for demonstration of the aeroelastic coupling procedure by using ENSAERO (NASA Ames Research Center CFD code) and a finite element wing-box code (developed as part of this research).

Development of Safety Analysis Code System of Beam Transport and Core for Accelerator Driven System

NASA Astrophysics Data System (ADS)

Aizawa, Naoto; Iwasaki, Tomohiko

2014-06-01

Safety analysis code system of beam transport and core for accelerator driven system (ADS) is developed for the analyses of beam transients such as the change of the shape and position of incident beam. The code system consists of the beam transport analysis part and the core analysis part. TRACE 3-D is employed in the beam transport analysis part, and the shape and incident position of beam at the target are calculated. In the core analysis part, the neutronics, thermo-hydraulics and cladding failure analyses are performed by the use of ADS dynamic calculation code ADSE on the basis of the external source database calculated by PHITS and the cross section database calculated by SRAC, and the programs of the cladding failure analysis for thermoelastic and creep. By the use of the code system, beam transient analyses are performed for the ADS proposed by Japan Atomic Energy Agency. As a result, the rapid increase of the cladding temperature happens and the plastic deformation is caused in several seconds. In addition, the cladding is evaluated to be failed by creep within a hundred seconds. These results have shown that the beam transients have caused a cladding failure.

EBT reactor systems analysis and cost code: description and users guide (Version 1)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Santoro, R.T.; Uckan, N.A.; Barnes, J.M.

1984-06-01

An ELMO Bumpy Torus (EBT) reactor systems analysis and cost code that incorporates the most recent advances in EBT physics has been written. The code determines a set of reactors that fall within an allowed operating window determined from the coupling of ring and core plasma properties and the self-consistent treatment of the coupled ring-core stability and power balance requirements. The essential elements of the systems analysis and cost code are described, along with the calculational sequences leading to the specification of the reactor options and their associated costs. The input parameters, the constraints imposed upon them, and the operatingmore » range over which the code provides valid results are discussed. A sample problem and the interpretation of the results are also presented.« less

Research and Trends in the Field of Technology-Enhanced Learning from 2006 to 2011: A Content Analysis of Quick Response Code (QR-Code) and Its Application in Selected Studies

ERIC Educational Resources Information Center

Hau, Goh Bak; Siraj, Saedah; Alias, Norlidah; Rauf, Rose Amnah Abd.; Zakaria, Abd. Razak; Darusalam, Ghazali

2013-01-01

This study provides a content analysis of selected articles in the field of QR code and its application in educational context that were published in journals and proceedings of international conferences and workshops from 2006 to 2011. These articles were cross analysed by published years, journal, and research topics. Further analysis was…

Computer codes developed and under development at Lewis

NASA Technical Reports Server (NTRS)

Chamis, Christos C.

1992-01-01

The objective of this summary is to provide a brief description of: (1) codes developed or under development at LeRC; and (2) the development status of IPACS with some typical early results. The computer codes that have been developed and/or are under development at LeRC are listed in the accompanying charts. This list includes: (1) the code acronym; (2) select physics descriptors; (3) current enhancements; and (4) present (9/91) code status with respect to its availability and documentation. The computer codes list is grouped by related functions such as: (1) composite mechanics; (2) composite structures; (3) integrated and 3-D analysis; (4) structural tailoring; and (5) probabilistic structural analysis. These codes provide a broad computational simulation infrastructure (technology base-readiness) for assessing the structural integrity/durability/reliability of propulsion systems. These codes serve two other very important functions: they provide an effective means of technology transfer; and they constitute a depository of corporate memory.

Improvements in the MGA Code Provide Flexibility and Better Error Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ruhter, W D; Kerr, J

2005-05-26

The Multi-Group Analysis (MGA) code is widely used to determine nondestructively the relative isotopic abundances of plutonium by gamma-ray spectrometry. MGA users have expressed concern about the lack of flexibility and transparency in the code. Users often have to ask the code developers for modifications to the code to accommodate new measurement situations, such as additional peaks being present in the plutonium spectrum or expected peaks being absent. We are testing several new improvements to a prototype, general gamma-ray isotopic analysis tool with the intent of either revising or replacing the MGA code. These improvements will give the user themore » ability to modify, add, or delete the gamma- and x-ray energies and branching intensities used by the code in determining a more precise gain and in the determination of the relative detection efficiency. We have also fully integrated the determination of the relative isotopic abundances with the determination of the relative detection efficiency to provide a more accurate determination of the errors in the relative isotopic abundances. We provide details in this paper on these improvements and a comparison of results obtained with current versions of the MGA code.« less

A Computer Program for Flow-Log Analysis of Single Holes (FLASH)

USGS Publications Warehouse

Day-Lewis, F. D.; Johnson, C.D.; Paillet, Frederick L.; Halford, K.J.

2011-01-01

A new computer program, FLASH (Flow-Log Analysis of Single Holes), is presented for the analysis of borehole vertical flow logs. The code is based on an analytical solution for steady-state multilayer radial flow to a borehole. The code includes options for (1) discrete fractures and (2) multilayer aquifers. Given vertical flow profiles collected under both ambient and stressed (pumping or injection) conditions, the user can estimate fracture (or layer) transmissivities and far-field hydraulic heads. FLASH is coded in Microsoft Excel with Visual Basic for Applications routines. The code supports manual and automated model calibration. ?? 2011, The Author(s). Ground Water ?? 2011, National Ground Water Association.

Barriers to Early Detection of Breast Cancer Among African American Females Over Age of 55

DTIC Science & Technology

2005-02-01

used for data analysis. NUDIST , software for qualitative data analysis will be used for systematic coding. All transcripts, as well as interviewer notes...will be coded in NUDIST . Dr. Smith and Mr. Worts will jointly develop the NUDIST coding system. Each of them will separately code each transcript and...already provided training in NUDIST to Dr. Smith and Mr. Worts. All interviews will be conducted by the Principal Investigator for this study who is

Development and application of structural dynamics analysis capabilities

NASA Technical Reports Server (NTRS)

Heinemann, Klaus W.; Hozaki, Shig

1994-01-01

Extensive research activities were performed in the area of multidisciplinary modeling and simulation of aerospace vehicles that are relevant to NASA Dryden Flight Research Facility. The efforts involved theoretical development, computer coding, and debugging of the STARS code. New solution procedures were developed in such areas as structures, CFD, and graphics, among others. Furthermore, systems-oriented codes were developed for rendering the code truly multidisciplinary and rather automated in nature. Also, work was performed in pre- and post-processing of engineering analysis data.

Simplified diagnostic coding sheet for computerized data storage and analysis in ophthalmology.

PubMed

Tauber, J; Lahav, M

1987-11-01

A review of currently-available diagnostic coding systems revealed that most are either too abbreviated or too detailed. We have compiled a simplified diagnostic coding sheet based on the International Coding and Diagnosis (ICD-9), which is both complete and easy to use in a general practice. The information is transferred to a computer, which uses the relevant (ICD-9) diagnoses as database and can be retrieved later for display of patients' problems or analysis of clinical data.

Surface electromyography and ultrasound evaluation of pelvic floor muscles in hyperandrogenic women.

PubMed

Vassimon, Flávia Ignácio Antonio; Ferreira, Cristine Homsi Jorge; Martins, Wellington Paula; Ferriani, Rui Alberto; Batista, Roberta Leopoldino de Andrade; Bo, Kari

2016-04-01

High levels of androgens increase muscle mass. Due to the characteristics of hyperandrogenism in polycystic ovary syndrome (PCOS), it is plausible that women with PCOS may have increased pelvic floor muscle (PFM) thickness and neuromuscular activity levels compared with controls. The aim of this study was to assess PFM thickness and neuromuscular activity among hyperandrogenic women with PCOS and controls. This was an observational, cross-sectional, case-control study evaluating PFM by ultrasound (US) and surface electromyography (sEMG) in nonobese women with and without PCOS. Seventy-two women were divided into two groups: PCOS (n = 33) and controls (n = 39). PFM thickness during contraction was assessed by US (Vingmed CFM 800). Pelvic floor muscle activity was assessed by sEMG (MyoTrac Infinit) during contractions at different time lengths: quick, and 8 and 60 s. Descriptive analysis, analysis of variance (ANOVA), and Student's t test were used for statistical analyses. There were no significant differences in PFM sEMG activity between PCOS and controls in any of the contractions: quick contraction (73.23 mV/ 71.56 mV; p = 0.62), 8 s (55.77 mV/ 54.17 mV; p = 0.74), and 60 s (49.26 mV/ 47.32 mV; p = 0.68), respectively. There was no difference in PFM thickness during contractions evaluated by US between PCOS and controls (12.78 mm/ 13.43 mm; p =  .48). This study did not find statistically significant differences in pelvic floor muscle thickness or in muscle activity between PCOS women and controls.

Teaching, Morality, and Responsibility: A Structuralist Analysis of a Teachers' Code of Conduct

ERIC Educational Resources Information Center

Shortt, Damien; Hallett, Fiona; Spendlove, David; Hardy, Graham; Barton, Amanda

2012-01-01

In this paper we conduct a Structuralist analysis of the General Teaching Council for England's "Code of Conduct and Practice for Registered Teachers" in order to reveal how teachers are required to fulfil an apparently impossible social role. The GTCE's "Code," we argue, may be seen as an attempt by a government agency to…

New Tool Released for Engine-Airframe Blade-Out Structural Simulations

NASA Technical Reports Server (NTRS)

Lawrence, Charles

2004-01-01

Researchers at the NASA Glenn Research Center have enhanced a general-purpose finite element code, NASTRAN, for engine-airframe structural simulations during steady-state and transient operating conditions. For steady-state simulations, the code can predict critical operating speeds, natural modes of vibration, and forced response (e.g., cabin noise and component fatigue). The code can be used to perform static analysis to predict engine-airframe response and component stresses due to maneuver loads. For transient response, the simulation code can be used to predict response due to bladeoff events and subsequent engine shutdown and windmilling conditions. In addition, the code can be used as a pretest analysis tool to predict the results of the bladeout test required for FAA certification of new and derivative aircraft engines. Before the present analysis code was developed, all the major aircraft engine and airframe manufacturers in the United States and overseas were performing similar types of analyses to ensure the structural integrity of engine-airframe systems. Although there were many similarities among the analysis procedures, each manufacturer was developing and maintaining its own structural analysis capabilities independently. This situation led to high software development and maintenance costs, complications with manufacturers exchanging models and results, and limitations in predicting the structural response to the desired degree of accuracy. An industry-NASA team was formed to overcome these problems by developing a common analysis tool that would satisfy all the structural analysis needs of the industry and that would be available and supported by a commercial software vendor so that the team members would be relieved of maintenance and development responsibilities. Input from all the team members was used to ensure that everyone's requirements were satisfied and that the best technology was incorporated into the code. Furthermore, because the code would be distributed by a commercial software vendor, it would be more readily available to engine and airframe manufacturers, as well as to nonaircraft companies that did not previously have access to this capability.

National Combustion Code Parallel Performance Enhancements

NASA Technical Reports Server (NTRS)

Quealy, Angela; Benyo, Theresa (Technical Monitor)

2002-01-01

The National Combustion Code (NCC) is being developed by an industry-government team for the design and analysis of combustion systems. The unstructured grid, reacting flow code uses a distributed memory, message passing model for its parallel implementation. The focus of the present effort has been to improve the performance of the NCC code to meet combustor designer requirements for model accuracy and analysis turnaround time. Improving the performance of this code contributes significantly to the overall reduction in time and cost of the combustor design cycle. This report describes recent parallel processing modifications to NCC that have improved the parallel scalability of the code, enabling a two hour turnaround for a 1.3 million element fully reacting combustion simulation on an SGI Origin 2000.

Performance enhancement of optical code-division multiple-access systems using transposed modified Walsh code

NASA Astrophysics Data System (ADS)

Sikder, Somali; Ghosh, Shila

2018-02-01

This paper presents the construction of unipolar transposed modified Walsh code (TMWC) and analysis of its performance in optical code-division multiple-access (OCDMA) systems. Specifically, the signal-to-noise ratio, bit error rate (BER), cardinality, and spectral efficiency were investigated. The theoretical analysis demonstrated that the wavelength-hopping time-spreading system using TMWC was robust against multiple-access interference and more spectrally efficient than systems using other existing OCDMA codes. In particular, the spectral efficiency was calculated to be 1.0370 when TMWC of weight 3 was employed. The BER and eye pattern for the designed TMWC were also successfully obtained using OptiSystem simulation software. The results indicate that the proposed code design is promising for enhancing network capacity.

Analysis of Phenix end-of-life natural convection test with the MARS-LMR code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jeong, H. Y.; Ha, K. S.; Lee, K. L.

The end-of-life test of Phenix reactor performed by the CEA provided an opportunity to have reliable and valuable test data for the validation and verification of a SFR system analysis code. KAERI joined this international program for the analysis of Phenix end-of-life natural circulation test coordinated by the IAEA from 2008. The main objectives of this study were to evaluate the capability of existing SFR system analysis code MARS-LMR and to identify any limitation of the code. The analysis was performed in three stages: pre-test analysis, blind posttest analysis, and final post-test analysis. In the pre-test analysis, the design conditionsmore » provided by the CEA were used to obtain a prediction of the test. The blind post-test analysis was based on the test conditions measured during the tests but the test results were not provided from the CEA. The final post-test analysis was performed to predict the test results as accurate as possible by improving the previous modeling of the test. Based on the pre-test analysis and blind test analysis, the modeling for heat structures in the hot pool and cold pool, steel structures in the core, heat loss from roof and vessel, and the flow path at core outlet were reinforced in the final analysis. The results of the final post-test analysis could be characterized into three different phases. In the early phase, the MARS-LMR simulated the heat-up process correctly due to the enhanced heat structure modeling. In the mid phase before the opening of SG casing, the code reproduced the decrease of core outlet temperature successfully. Finally, in the later phase the increase of heat removal by the opening of the SG opening was well predicted with the MARS-LMR code. (authors)« less

Performance Analysis of Hybrid ARQ Protocols in a Slotted Code Division Multiple-Access Network

DTIC Science & Technology

1989-08-01

Convolutional Codes . in Proc Int. Conf. Commun., 21.4.1-21.4.5, 1987. [27] J. Hagenauer. Rate Compatible Punctured Convolutional Codes . in Proc Int. Conf...achieved by using a low rate (r = 0.5), high constraint length (e.g., 32) punctured convolutional code . Code puncturing provides for a variable rate code ...investigated the use of convolutional codes in Type II Hybrid ARQ protocols. The error

Development of the Off-line Analysis Code for GODDESS

NASA Astrophysics Data System (ADS)

Garland, Heather; Cizewski, Jolie; Lepailleur, Alex; Walters, David; Pain, Steve; Smith, Karl

2016-09-01

Determining (n, γ) cross sections on unstable nuclei is important for understanding the r-process that is theorized to occur in supernovae and neutron-star mergers. However, (n, γ) reactions are difficult to measure directly because of the short lifetime of the involved neutron rich nuclei. A possible surrogate for the (n, γ) reaction is the (d,p γ) reaction; the measurement of these reactions in inverse kinematics is part of the scope of GODDESS - Gammasphere ORRUBA (Oak Ridge Rutgers University Barrel Array): Dual Detectors for Experimental Structure Studies. The development of an accurate and efficient off-line analysis code for GODDESS experiments is not only essential, but also provides a unique opportunity to create an analysis code designed specifically for transfer reaction experiments. The off-line analysis code has been developed to produce histograms from the binary data file to determine how to best sort events. Recent developments in the off-line analysis code will be presented as well as details on the energy and position calibrations for the ORRUBA detectors. This work is supported in part by the U.S. Department of Energy and National Science Foundation.

Color Coding of Circuit Quantities in Introductory Circuit Analysis Instruction

ERIC Educational Resources Information Center

Reisslein, Jana; Johnson, Amy M.; Reisslein, Martin

2015-01-01

Learning the analysis of electrical circuits represented by circuit diagrams is often challenging for novice students. An open research question in electrical circuit analysis instruction is whether color coding of the mathematical symbols (variables) that denote electrical quantities can improve circuit analysis learning. The present study…

Maximum likelihood decoding analysis of accumulate-repeat-accumulate codes

NASA Technical Reports Server (NTRS)

Abbasfar, A.; Divsalar, D.; Yao, K.

2004-01-01

In this paper, the performance of the repeat-accumulate codes with (ML) decoding are analyzed and compared to random codes by very tight bounds. Some simple codes are shown that perform very close to Shannon limit with maximum likelihood decoding.

Response surface method in geotechnical/structural analysis, phase 1

NASA Astrophysics Data System (ADS)

Wong, F. S.

1981-02-01

In the response surface approach, an approximating function is fit to a long running computer code based on a limited number of code calculations. The approximating function, called the response surface, is then used to replace the code in subsequent repetitive computations required in a statistical analysis. The procedure of the response surface development and feasibility of the method are shown using a sample problem in slop stability which is based on data from centrifuge experiments of model soil slopes and involves five random soil parameters. It is shown that a response surface can be constructed based on as few as four code calculations and that the response surface is computationally extremely efficient compared to the code calculation. Potential applications of this research include probabilistic analysis of dynamic, complex, nonlinear soil/structure systems such as slope stability, liquefaction, and nuclear reactor safety.

Moderate Deviation Analysis for Classical Communication over Quantum Channels

NASA Astrophysics Data System (ADS)

Chubb, Christopher T.; Tan, Vincent Y. F.; Tomamichel, Marco

2017-11-01

We analyse families of codes for classical data transmission over quantum channels that have both a vanishing probability of error and a code rate approaching capacity as the code length increases. To characterise the fundamental tradeoff between decoding error, code rate and code length for such codes we introduce a quantum generalisation of the moderate deviation analysis proposed by Altŭg and Wagner as well as Polyanskiy and Verdú. We derive such a tradeoff for classical-quantum (as well as image-additive) channels in terms of the channel capacity and the channel dispersion, giving further evidence that the latter quantity characterises the necessary backoff from capacity when transmitting finite blocks of classical data. To derive these results we also study asymmetric binary quantum hypothesis testing in the moderate deviations regime. Due to the central importance of the latter task, we expect that our techniques will find further applications in the analysis of other quantum information processing tasks.

Capabilities needed for the next generation of thermo-hydraulic codes for use in real time applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arndt, S.A.

1997-07-01

The real-time reactor simulation field is currently at a crossroads in terms of the capability to perform real-time analysis using the most sophisticated computer codes. Current generation safety analysis codes are being modified to replace simplified codes that were specifically designed to meet the competing requirement for real-time applications. The next generation of thermo-hydraulic codes will need to have included in their specifications the specific requirement for use in a real-time environment. Use of the codes in real-time applications imposes much stricter requirements on robustness, reliability and repeatability than do design and analysis applications. In addition, the need for codemore » use by a variety of users is a critical issue for real-time users, trainers and emergency planners who currently use real-time simulation, and PRA practitioners who will increasingly use real-time simulation for evaluating PRA success criteria in near real-time to validate PRA results for specific configurations and plant system unavailabilities.« less

Colour cyclic code for Brillouin distributed sensors

NASA Astrophysics Data System (ADS)

Le Floch, Sébastien; Sauser, Florian; Llera, Miguel; Rochat, Etienne

2015-09-01

For the first time, a colour cyclic coding (CCC) is theoretically and experimentally demonstrated for Brillouin optical time-domain analysis (BOTDA) distributed sensors. Compared to traditional intensity-modulated cyclic codes, the code presents an additional gain of √2 while keeping the same number of sequences as for a colour coding. A comparison with a standard BOTDA sensor is realized and validates the theoretical coding gain.

Design Analysis of SNS Target StationBiological Shielding Monoligh with Proton Power Uprate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bekar, Kursat B.; Ibrahim, Ahmad M.

2017-05-01

This report documents the analysis of the dose rate in the experiment area outside the Spallation Neutron Source (SNS) target station shielding monolith with proton beam energy of 1.3 GeV. The analysis implemented a coupled three dimensional (3D)/two dimensional (2D) approach that used both the Monte Carlo N-Particle Extended (MCNPX) 3D Monte Carlo code and the Discrete Ordinates Transport (DORT) two dimensional deterministic code. The analysis with proton beam energy of 1.3 GeV showed that the dose rate in continuously occupied areas on the lateral surface outside the SNS target station shielding monolith is less than 0.25 mrem/h, which compliesmore » with the SNS facility design objective. However, the methods and codes used in this analysis are out of date and unsupported, and the 2D approximation of the target shielding monolith does not accurately represent the geometry. We recommend that this analysis is updated with modern codes and libraries such as ADVANTG or SHIFT. These codes have demonstrated very high efficiency in performing full 3D radiation shielding analyses of similar and even more difficult problems.« less

Airfoil Vibration Dampers program

NASA Technical Reports Server (NTRS)

Cook, Robert M.

1991-01-01

The Airfoil Vibration Damper program has consisted of an analysis phase and a testing phase. During the analysis phase, a state-of-the-art computer code was developed, which can be used to guide designers in the placement and sizing of friction dampers. The use of this computer code was demonstrated by performing representative analyses on turbine blades from the High Pressure Oxidizer Turbopump (HPOTP) and High Pressure Fuel Turbopump (HPFTP) of the Space Shuttle Main Engine (SSME). The testing phase of the program consisted of performing friction damping tests on two different cantilever beams. Data from these tests provided an empirical check on the accuracy of the computer code developed in the analysis phase. Results of the analysis and testing showed that the computer code can accurately predict the performance of friction dampers. In addition, a valuable set of friction damping data was generated, which can be used to aid in the design of friction dampers, as well as provide benchmark test cases for future code developers.

The Use and Effectiveness of Triple Multiplex System for Coding Region Single Nucleotide Polymorphism in Mitochondrial DNA Typing of Archaeologically Obtained Human Skeletons from Premodern Joseon Tombs of Korea

PubMed Central

Oh, Chang Seok; Lee, Soong Deok; Kim, Yi-Suk; Shin, Dong Hoon

2015-01-01

Previous study showed that East Asian mtDNA haplogroups, especially those of Koreans, could be successfully assigned by the coupled use of analyses on coding region SNP markers and control region mutation motifs. In this study, we tried to see if the same triple multiplex analysis for coding regions SNPs could be also applicable to ancient samples from East Asia as the complementation for sequence analysis of mtDNA control region. By the study on Joseon skeleton samples, we know that mtDNA haplogroup determined by coding region SNP markers successfully falls within the same haplogroup that sequence analysis on control region can assign. Considering that ancient samples in previous studies make no small number of errors in control region mtDNA sequencing, coding region SNP analysis can be used as good complimentary to the conventional haplogroup determination, especially of archaeological human bone samples buried underground over long periods. PMID:26345190

Visual Computing Environment Workshop

NASA Technical Reports Server (NTRS)

Lawrence, Charles (Compiler)

1998-01-01

The Visual Computing Environment (VCE) is a framework for intercomponent and multidisciplinary computational simulations. Many current engineering analysis codes simulate various aspects of aircraft engine operation. For example, existing computational fluid dynamics (CFD) codes can model the airflow through individual engine components such as the inlet, compressor, combustor, turbine, or nozzle. Currently, these codes are run in isolation, making intercomponent and complete system simulations very difficult to perform. In addition, management and utilization of these engineering codes for coupled component simulations is a complex, laborious task, requiring substantial experience and effort. To facilitate multicomponent aircraft engine analysis, the CFD Research Corporation (CFDRC) is developing the VCE system. This system, which is part of NASA's Numerical Propulsion Simulation System (NPSS) program, can couple various engineering disciplines, such as CFD, structural analysis, and thermal analysis.

Mads.jl

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vesselinov, Velimir; O'Malley, Daniel; Lin, Youzuo

2016-07-01

Mads.jl (Model analysis and decision support in Julia) is a code that streamlines the process of using data and models for analysis and decision support. It is based on another open-source code developed at LANL and written in C/C++ (MADS; http://mads.lanl.gov; LA-CC-11- 035). Mads.jl can work with external models of arbitrary complexity as well as built-in models of flow and transport in porous media. It enables a number of data- and model-based analyses including model calibration, sensitivity analysis, uncertainty quantification, and decision analysis. The code also can use a series of alternative adaptive computational techniques for Bayesian sampling, Monte Carlo,more » and Bayesian Information-Gap Decision Theory. The code is implemented in the Julia programming language, and has high-performance (parallel) and memory management capabilities. The code uses a series of third party modules developed by others. The code development will also include contributions to the existing third party modules written in Julia; this contributions will be important for the efficient implementation of the algorithm used by Mads.jl. The code also uses a series of LANL developed modules that are developed by Dan O'Malley; these modules will be also a part of the Mads.jl release. Mads.jl will be released under GPL V3 license. The code will be distributed as a Git repo at gitlab.com and github.com. Mads.jl manual and documentation will be posted at madsjulia.lanl.gov.« less

Development of Web Interfaces for Analysis Codes

NASA Astrophysics Data System (ADS)

Emoto, M.; Watanabe, T.; Funaba, H.; Murakami, S.; Nagayama, Y.; Kawahata, K.

Several codes have been developed to analyze plasma physics. However, most of them are developed to run on supercomputers. Therefore, users who typically use personal computers (PCs) find it difficult to use these codes. In order to facilitate the widespread use of these codes, a user-friendly interface is required. The authors propose Web interfaces for these codes. To demonstrate the usefulness of this approach, the authors developed Web interfaces for two analysis codes. One of them is for FIT developed by Murakami. This code is used to analyze the NBI heat deposition, etc. Because it requires electron density profiles, electron temperatures, and ion temperatures as polynomial expressions, those unfamiliar with the experiments find it difficult to use this code, especially visitors from other institutes. The second one is for visualizing the lines of force in the LHD (large helical device) developed by Watanabe. This code is used to analyze the interference caused by the lines of force resulting from the various structures installed in the vacuum vessel of the LHD. This code runs on PCs; however, it requires that the necessary parameters be edited manually. Using these Web interfaces, users can execute these codes interactively.

Multidisciplinary High-Fidelity Analysis and Optimization of Aerospace Vehicles. Part 1; Formulation

NASA Technical Reports Server (NTRS)

Walsh, J. L.; Townsend, J. C.; Salas, A. O.; Samareh, J. A.; Mukhopadhyay, V.; Barthelemy, J.-F.

2000-01-01

An objective of the High Performance Computing and Communication Program at the NASA Langley Research Center is to demonstrate multidisciplinary shape and sizing optimization of a complete aerospace vehicle configuration by using high-fidelity, finite element structural analysis and computational fluid dynamics aerodynamic analysis in a distributed, heterogeneous computing environment that includes high performance parallel computing. A software system has been designed and implemented to integrate a set of existing discipline analysis codes, some of them computationally intensive, into a distributed computational environment for the design of a highspeed civil transport configuration. The paper describes the engineering aspects of formulating the optimization by integrating these analysis codes and associated interface codes into the system. The discipline codes are integrated by using the Java programming language and a Common Object Request Broker Architecture (CORBA) compliant software product. A companion paper presents currently available results.

Performance Analysis and Optimization on the UCLA Parallel Atmospheric General Circulation Model Code

NASA Technical Reports Server (NTRS)

Lou, John; Ferraro, Robert; Farrara, John; Mechoso, Carlos

1996-01-01

An analysis is presented of several factors influencing the performance of a parallel implementation of the UCLA atmospheric general circulation model (AGCM) on massively parallel computer systems. Several modificaitons to the original parallel AGCM code aimed at improving its numerical efficiency, interprocessor communication cost, load-balance and issues affecting single-node code performance are discussed.

"SEN's Completely Different Now": Critical Discourse Analysis of Three "Codes of Practice for Special Educational Needs" (1994, 2001, 2015)

ERIC Educational Resources Information Center

Lehane, Teresa

2017-01-01

Regardless of the differing shades of neo-liberalism, successive governments have claimed to champion the cause of "special educational needs and/or disability" (SEND) through official Codes of Practice in 1994, 2001 and 2015. This analysis and comparison of the three Codes of Practice aims to contribute to the debate by exploring…

The Evolution of a Coding Schema in a Paced Program of Research

ERIC Educational Resources Information Center

Winters, Charlene A.; Cudney, Shirley; Sullivan, Therese

2010-01-01

A major task involved in the management, analysis, and integration of qualitative data is the development of a coding schema to facilitate the analytic process. Described in this paper is the evolution of a coding schema that was used in the analysis of qualitative data generated from online forums of middle-aged women with chronic conditions who…

Java Source Code Analysis for API Migration to Embedded Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Winter, Victor; McCoy, James A.; Guerrero, Jonathan

Embedded systems form an integral part of our technological infrastructure and oftentimes play a complex and critical role within larger systems. From the perspective of reliability, security, and safety, strong arguments can be made favoring the use of Java over C in such systems. In part, this argument is based on the assumption that suitable subsets of Java’s APIs and extension libraries are available to embedded software developers. In practice, a number of Java-based embedded processors do not support the full features of the JVM. For such processors, source code migration is a mechanism by which key abstractions offered bymore » APIs and extension libraries can made available to embedded software developers. The analysis required for Java source code-level library migration is based on the ability to correctly resolve element references to their corresponding element declarations. A key challenge in this setting is how to perform analysis for incomplete source-code bases (e.g., subsets of libraries) from which types and packages have been omitted. This article formalizes an approach that can be used to extend code bases targeted for migration in such a manner that the threats associated the analysis of incomplete code bases are eliminated.« less

Iterative categorization (IC): a systematic technique for analysing qualitative data

PubMed Central

2016-01-01

Abstract The processes of analysing qualitative data, particularly the stage between coding and publication, are often vague and/or poorly explained within addiction science and research more broadly. A simple but rigorous and transparent technique for analysing qualitative textual data, developed within the field of addiction, is described. The technique, iterative categorization (IC), is suitable for use with inductive and deductive codes and can support a range of common analytical approaches, e.g. thematic analysis, Framework, constant comparison, analytical induction, content analysis, conversational analysis, discourse analysis, interpretative phenomenological analysis and narrative analysis. Once the data have been coded, the only software required is a standard word processing package. Worked examples are provided. PMID:26806155

Comparing Results from Constant Comparative and Computer Software Methods: A Reflection about Qualitative Data Analysis

ERIC Educational Resources Information Center

Putten, Jim Vander; Nolen, Amanda L.

2010-01-01

This study compared qualitative research results obtained by manual constant comparative analysis with results obtained by computer software analysis of the same data. An investigated about issues of trustworthiness and accuracy ensued. Results indicated that the inductive constant comparative data analysis generated 51 codes and two coding levels…

msCompare: A Framework for Quantitative Analysis of Label-free LC-MS Data for Comparative Candidate Biomarker Studies*

PubMed Central

Hoekman, Berend; Breitling, Rainer; Suits, Frank; Bischoff, Rainer; Horvatovich, Peter

2012-01-01

Data processing forms an integral part of biomarker discovery and contributes significantly to the ultimate result. To compare and evaluate various publicly available open source label-free data processing workflows, we developed msCompare, a modular framework that allows the arbitrary combination of different feature detection/quantification and alignment/matching algorithms in conjunction with a novel scoring method to evaluate their overall performance. We used msCompare to assess the performance of workflows built from modules of publicly available data processing packages such as SuperHirn, OpenMS, and MZmine and our in-house developed modules on peptide-spiked urine and trypsin-digested cerebrospinal fluid (CSF) samples. We found that the quality of results varied greatly among workflows, and interestingly, heterogeneous combinations of algorithms often performed better than the homogenous workflows. Our scoring method showed that the union of feature matrices of different workflows outperformed the original homogenous workflows in some cases. msCompare is open source software (https://trac.nbic.nl/mscompare), and we provide a web-based data processing service for our framework by integration into the Galaxy server of the Netherlands Bioinformatics Center (http://galaxy.nbic.nl/galaxy) to allow scientists to determine which combination of modules provides the most accurate processing for their particular LC-MS data sets. PMID:22318370

[Foliage clumping index of main vegetation types in Daxing'an Mountains, Northeast China].

PubMed

Huang, Ting; Fan, Wen Yi; Mao, Xue Gang; Yu, Ying

2017-03-18

The foliage clumping index quantifies the cluster degree of the leaf spatial distribution under random canopy. It is of comparable importance for establishment of ecological models. MODIS BRDF model parameter products (MCD43A1 data) and land cover types (MCD12Q1 data) were used in this study to simulate the reflectivity of the hot spots and dark spots, and calculate the normalized difference between hotspot and darkspot (NDHD) based on the Ross-Li semi-empirical model. Least square method was then used to simulate the relationship between NDHD and the foliage clumping index and foliage clumping index products of 500-m resolution in August 2014 were retrieved. Measurements of the foliage clumping index in Daxing'an Mountains were conducted by using the TRAC (Tracing Radiation and Architecture of Canopies) sampling instrument for mo-del validation and analysis. Results showed that it was a feasible algorithm to retrieve clumping index from MCD43A1 product with the correlation of simulated data and the measured data of significance (R 2 =0.8879). The MODIS near infrared wave band was more sensitive than that on red band to foliage clumping index change. With the increase of the solar zenith angle, the clumping index retrieved by Ross-Li model had a linear increase (R 2 =0.9699), which indicated that the foliage clumping index related to the solar zenith angle.

An investigation of error characteristics and coding performance

NASA Technical Reports Server (NTRS)

Ebel, William J.; Ingels, Frank M.

1993-01-01

The first year's effort on NASA Grant NAG5-2006 was an investigation to characterize typical errors resulting from the EOS dorn link. The analysis methods developed for this effort were used on test data from a March 1992 White Sands Terminal Test. The effectiveness of a concatenated coding scheme of a Reed Solomon outer code and a convolutional inner code versus a Reed Solomon only code scheme has been investigated as well as the effectiveness of a Periodic Convolutional Interleaver in dispersing errors of certain types. The work effort consisted of development of software that allows simulation studies with the appropriate coding schemes plus either simulated data with errors or actual data with errors. The software program is entitled Communication Link Error Analysis (CLEAN) and models downlink errors, forward error correcting schemes, and interleavers.

Incorporating Manual and Autonomous Code Generation

NASA Technical Reports Server (NTRS)

McComas, David

1998-01-01

Code can be generated manually or using code-generated software tools, but how do you interpret the two? This article looks at a design methodology that combines object-oriented design with autonomic code generation for attitude control flight software. Recent improvements in space flight computers are allowing software engineers to spend more time engineering the applications software. The application developed was the attitude control flight software for an astronomical satellite called the Microwave Anisotropy Probe (MAP). The MAP flight system is being designed, developed, and integrated at NASA's Goddard Space Flight Center. The MAP controls engineers are using Integrated Systems Inc.'s MATRIXx for their controls analysis. In addition to providing a graphical analysis for an environment, MATRIXx includes an autonomic code generation facility called AutoCode. This article examines the forces that shaped the final design and describes three highlights of the design process: (1) Defining the manual to autonomic code interface; (2) Applying object-oriented design to the manual flight code; (3) Implementing the object-oriented design in C.

Performance optimization of spectral amplitude coding OCDMA system using new enhanced multi diagonal code

NASA Astrophysics Data System (ADS)

Imtiaz, Waqas A.; Ilyas, M.; Khan, Yousaf

2016-11-01

This paper propose a new code to optimize the performance of spectral amplitude coding-optical code division multiple access (SAC-OCDMA) system. The unique two-matrix structure of the proposed enhanced multi diagonal (EMD) code and effective correlation properties, between intended and interfering subscribers, significantly elevates the performance of SAC-OCDMA system by negating multiple access interference (MAI) and associated phase induce intensity noise (PIIN). Performance of SAC-OCDMA system based on the proposed code is thoroughly analyzed for two detection techniques through analytic and simulation analysis by referring to bit error rate (BER), signal to noise ratio (SNR) and eye patterns at the receiving end. It is shown that EMD code while using SDD technique provides high transmission capacity, reduces the receiver complexity, and provides better performance as compared to complementary subtraction detection (CSD) technique. Furthermore, analysis shows that, for a minimum acceptable BER of 10-9 , the proposed system supports 64 subscribers at data rates of up to 2 Gbps for both up-down link transmission.

Sensitivity Analysis and Uncertainty Quantification for the LAMMPS Molecular Dynamics Simulation Code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Picard, Richard Roy; Bhat, Kabekode Ghanasham

2017-07-18

We examine sensitivity analysis and uncertainty quantification for molecular dynamics simulation. Extreme (large or small) output values for the LAMMPS code often occur at the boundaries of input regions, and uncertainties in those boundary values are overlooked by common SA methods. Similarly, input values for which code outputs are consistent with calibration data can also occur near boundaries. Upon applying approaches in the literature for imprecise probabilities (IPs), much more realistic results are obtained than for the complacent application of standard SA and code calibration.

Space shuttle main engine numerical modeling code modifications and analysis

NASA Technical Reports Server (NTRS)

Ziebarth, John P.

1988-01-01

The user of computational fluid dynamics (CFD) codes must be concerned with the accuracy and efficiency of the codes if they are to be used for timely design and analysis of complicated three-dimensional fluid flow configurations. A brief discussion of how accuracy and efficiency effect the CFD solution process is given. A more detailed discussion of how efficiency can be enhanced by using a few Cray Research Inc. utilities to address vectorization is presented and these utilities are applied to a three-dimensional Navier-Stokes CFD code (INS3D).

General practitioners’ justifications for therapeutic inertia in cardiovascular prevention: an empirically grounded typology

PubMed Central

Lebeau, Jean-Pierre; Cadwallader, Jean-Sébastien; Vaillant-Roussel, Hélène; Pouchain, Denis; Yaouanc, Virginie; Aubin-Auger, Isabelle; Mercier, Alain; Rusch, Emmanuel; Remmen, Roy; Vermeire, Etienne; Hendrickx, Kristin

2016-01-01

Objective To construct a typology of general practitioners’ (GPs) responses regarding their justification of therapeutic inertia in cardiovascular primary prevention for high-risk patients with hypertension. Design Empirically grounded construction of typology. Types were defined by attributes derived from the qualitative analysis of GPs’ reported reasons for inaction. Participants 256 GPs randomised in the intervention group of a cluster randomised controlled trial. Setting GPs members of 23 French Regional Colleges of Teachers in General Practice, included in the EffectS of a multifaceted intervention on CArdiovascular risk factors in high-risk hyPErtensive patients (ESCAPE) trial. Data collection and analysis The database consisted of 2638 written responses given by the GPs to an open-ended question asking for the reasons why drug treatment was not changed as suggested by the national guidelines. All answers were coded using constant comparison analysis. A matrix analysis of codes per GP allowed the construction of a response typology, where types were defined by codes as attributes. Initial coding and definition of types were performed independently by two teams. Results Initial coding resulted in a list of 69 codes in the final codebook, representing 4764 coded references in the question responses. A typology including seven types was constructed. 100 GPs were allocated to one and only one of these types, while 25 GPs did not provide enough data to allow classification. Types (numbers of GPs allocated) were: ‘optimists’ (28), ‘negotiators’ (20), ‘checkers’ (15), ‘contextualisers’ (13), ‘cautious’ (11), ‘rounders’ (8) and ‘scientists’ (5). For the 36 GPs that provided 50 or more coded references, analysis of the code evolution over time and across patients showed a consistent belonging to the initial type for any given GP. Conclusion This typology could provide GPs with some insight into their general ways of considering changes in the treatment/management of cardiovascular risk factors and guide design of specific physician-centred interventions to reduce inappropriate inaction. Trial registration number NCT00348855. PMID:27178974

Vibration Response Models of a Stiffened Aluminum Plate Excited by a Shaker

NASA Technical Reports Server (NTRS)

Cabell, Randolph H.

2008-01-01

Numerical models of structural-acoustic interactions are of interest to aircraft designers and the space program. This paper describes a comparison between two energy finite element codes, a statistical energy analysis code, a structural finite element code, and the experimentally measured response of a stiffened aluminum plate excited by a shaker. Different methods for modeling the stiffeners and the power input from the shaker are discussed. The results show that the energy codes (energy finite element and statistical energy analysis) accurately predicted the measured mean square velocity of the plate. In addition, predictions from an energy finite element code had the best spatial correlation with measured velocities. However, predictions from a considerably simpler, single subsystem, statistical energy analysis model also correlated well with the spatial velocity distribution. The results highlight a need for further work to understand the relationship between modeling assumptions and the prediction results.

Statistical properties of DNA sequences

NASA Technical Reports Server (NTRS)

Peng, C. K.; Buldyrev, S. V.; Goldberger, A. L.; Havlin, S.; Mantegna, R. N.; Simons, M.; Stanley, H. E.

1995-01-01

We review evidence supporting the idea that the DNA sequence in genes containing non-coding regions is correlated, and that the correlation is remarkably long range--indeed, nucleotides thousands of base pairs distant are correlated. We do not find such a long-range correlation in the coding regions of the gene. We resolve the problem of the "non-stationarity" feature of the sequence of base pairs by applying a new algorithm called detrended fluctuation analysis (DFA). We address the claim of Voss that there is no difference in the statistical properties of coding and non-coding regions of DNA by systematically applying the DFA algorithm, as well as standard FFT analysis, to every DNA sequence (33301 coding and 29453 non-coding) in the entire GenBank database. Finally, we describe briefly some recent work showing that the non-coding sequences have certain statistical features in common with natural and artificial languages. Specifically, we adapt to DNA the Zipf approach to analyzing linguistic texts. These statistical properties of non-coding sequences support the possibility that non-coding regions of DNA may carry biological information.

Transient dynamics capability at Sandia National Laboratories

NASA Technical Reports Server (NTRS)

Attaway, Steven W.; Biffle, Johnny H.; Sjaardema, G. D.; Heinstein, M. W.; Schoof, L. A.

1993-01-01

A brief overview of the transient dynamics capabilities at Sandia National Laboratories, with an emphasis on recent new developments and current research is presented. In addition, the Sandia National Laboratories (SNL) Engineering Analysis Code Access System (SEACAS), which is a collection of structural and thermal codes and utilities used by analysts at SNL, is described. The SEACAS system includes pre- and post-processing codes, analysis codes, database translation codes, support libraries, Unix shell scripts for execution, and an installation system. SEACAS is used at SNL on a daily basis as a production, research, and development system for the engineering analysts and code developers. Over the past year, approximately 190 days of CPU time were used by SEACAS codes on jobs running from a few seconds up to two and one-half days of CPU time. SEACAS is running on several different systems at SNL including Cray Unicos, Hewlett Packard PH-UX, Digital Equipment Ultrix, and Sun SunOS. An overview of SEACAS, including a short description of the codes in the system, are presented. Abstracts and references for the codes are listed at the end of the report.

Efficient genome-wide association in biobanks using topic modeling identifies multiple novel disease loci.

PubMed

McCoy, Thomas H; Castro, Victor M; Snapper, Leslie A; Hart, Kamber L; Perlis, Roy H

2017-08-31

Biobanks and national registries represent a powerful tool for genomic discovery, but rely on diagnostic codes that may be unreliable and fail to capture the relationship between related diagnoses. We developed an efficient means of conducting genome-wide association studies using combinations of diagnostic codes from electronic health records (EHR) for 10845 participants in a biobanking program at two large academic medical centers. Specifically, we applied latent Dirichilet allocation to fit 50 disease topics based on diagnostic codes, then conducted genome-wide common-variant association for each topic. In sensitivity analysis, these results were contrasted with those obtained from traditional single-diagnosis phenome-wide association analysis, as well as those in which only a subset of diagnostic codes are included per topic. In meta-analysis across three biobank cohorts, we identified 23 disease-associated loci with p<1e-15, including previously associated autoimmune disease loci. In all cases, observed significant associations were of greater magnitude than for single phenome-wide diagnostic codes, and incorporation of less strongly-loading diagnostic codes enhanced association. This strategy provides a more efficient means of phenome-wide association in biobanks with coded clinical data.

Efficient Genome-wide Association in Biobanks Using Topic Modeling Identifies Multiple Novel Disease Loci

PubMed Central

McCoy, Thomas H; Castro, Victor M; Snapper, Leslie A; Hart, Kamber L; Perlis, Roy H

2017-01-01

Biobanks and national registries represent a powerful tool for genomic discovery, but rely on diagnostic codes that can be unreliable and fail to capture relationships between related diagnoses. We developed an efficient means of conducting genome-wide association studies using combinations of diagnostic codes from electronic health records for 10,845 participants in a biobanking program at two large academic medical centers. Specifically, we applied latent Dirichilet allocation to fit 50 disease topics based on diagnostic codes, then conducted a genome-wide common-variant association for each topic. In sensitivity analysis, these results were contrasted with those obtained from traditional single-diagnosis phenome-wide association analysis, as well as those in which only a subset of diagnostic codes were included per topic. In meta-analysis across three biobank cohorts, we identified 23 disease-associated loci with p < 1e-15, including previously associated autoimmune disease loci. In all cases, observed significant associations were of greater magnitude than single phenome-wide diagnostic codes, and incorporation of less strongly loading diagnostic codes enhanced association. This strategy provides a more efficient means of identifying phenome-wide associations in biobanks with coded clinical data. PMID:28861588

DRG coding practice: a nationwide hospital survey in Thailand.

PubMed

Pongpirul, Krit; Walker, Damian G; Rahman, Hafizur; Robinson, Courtland

2011-10-31

Diagnosis Related Group (DRG) payment is preferred by healthcare reform in various countries but its implementation in resource-limited countries has not been fully explored. This study was aimed (1) to compare the characteristics of hospitals in Thailand that were audited with those that were not and (2) to develop a simplified scale to measure hospital coding practice. A questionnaire survey was conducted of 920 hospitals in the Summary and Coding Audit Database (SCAD hospitals, all of which were audited in 2008 because of suspicious reports of possible DRG miscoding); the questionnaire also included 390 non-SCAD hospitals. The questionnaire asked about general demographics of the hospitals, hospital coding structure and process, and also included a set of 63 opinion-oriented items on the current hospital coding practice. Descriptive statistics and exploratory factor analysis (EFA) were used for data analysis. SCAD and Non-SCAD hospitals were different in many aspects, especially the number of medical statisticians, experience of medical statisticians and physicians, as well as number of certified coders. Factor analysis revealed a simplified 3-factor, 20-item model to assess hospital coding practice and classify hospital intention. Hospital providers should not be assumed capable of producing high quality DRG codes, especially in resource-limited settings.

Upgrades of Two Computer Codes for Analysis of Turbomachinery

NASA Technical Reports Server (NTRS)

Chima, Rodrick V.; Liou, Meng-Sing

2005-01-01

Major upgrades have been made in two of the programs reported in "ive Computer Codes for Analysis of Turbomachinery". The affected programs are: Swift -- a code for three-dimensional (3D) multiblock analysis; and TCGRID, which generates a 3D grid used with Swift. Originally utilizing only a central-differencing scheme for numerical solution, Swift was augmented by addition of two upwind schemes that give greater accuracy but take more computing time. Other improvements in Swift include addition of a shear-stress-transport turbulence model for better prediction of adverse pressure gradients, addition of an H-grid capability for flexibility in modeling flows in pumps and ducts, and modification to enable simultaneous modeling of hub and tip clearances. Improvements in TCGRID include modifications to enable generation of grids for more complicated flow paths and addition of an option to generate grids compatible with the ADPAC code used at NASA and in industry. For both codes, new test cases were developed and documentation was updated. Both codes were converted to Fortran 90, with dynamic memory allocation. Both codes were also modified for ease of use in both UNIX and Windows operating systems.

Computer Code for Transportation Network Design and Analysis

DOT National Transportation Integrated Search

1977-01-01

This document describes the results of research into the application of the mathematical programming technique of decomposition to practical transportation network problems. A computer code called Catnap (for Control Analysis Transportation Network A...

Automated Detection and Analysis of Interplanetary Shocks with Real-Time Application

NASA Astrophysics Data System (ADS)

Vorotnikov, V.; Smith, C. W.; Hu, Q.; Szabo, A.; Skoug, R. M.; Cohen, C. M.

2006-12-01

The ACE real-time data stream provides web-based now-casting capabilities for solar wind conditions upstream of Earth. Our goal is to provide an automated code that finds and analyzes interplanetary shocks as they occur for possible real-time application to space weather nowcasting. Shock analysis algorithms based on the Rankine-Hugoniot jump conditions exist and are in wide-spread use today for the interactive analysis of interplanetary shocks yielding parameters such as shock speed and propagation direction and shock strength in the form of compression ratios. Although these codes can be automated in a reasonable manner to yield solutions not far from those obtained by user-directed interactive analysis, event detection presents an added obstacle and the first step in a fully automated analysis. We present a fully automated Rankine-Hugoniot analysis code that can scan the ACE science data, find shock candidates, analyze the events, obtain solutions in good agreement with those derived from interactive applications, and dismiss false positive shock candidates on the basis of the conservation equations. The intent is to make this code available to NOAA for use in real-time space weather applications. The code has the added advantage of being able to scan spacecraft data sets to provide shock solutions for use outside real-time applications and can easily be applied to science-quality data sets from other missions. Use of the code for this purpose will also be explored.

GLSENS: A Generalized Extension of LSENS Including Global Reactions and Added Sensitivity Analysis for the Perfectly Stirred Reactor

NASA Technical Reports Server (NTRS)

Bittker, David A.

1996-01-01

A generalized version of the NASA Lewis general kinetics code, LSENS, is described. The new code allows the use of global reactions as well as molecular processes in a chemical mechanism. The code also incorporates the capability of performing sensitivity analysis calculations for a perfectly stirred reactor rapidly and conveniently at the same time that the main kinetics calculations are being done. The GLSENS code has been extensively tested and has been found to be accurate and efficient. Nine example problems are presented and complete user instructions are given for the new capabilities. This report is to be used in conjunction with the documentation for the original LSENS code.

Combined coding and delay-throughput analysis for fading channels of mobile satellite communications

NASA Technical Reports Server (NTRS)

Wang, C. C.; Yan, Tsun-Yee

1986-01-01

This paper presents the analysis of using the punctured convolutional code with Viterbi decoding to improve communications reliability. The punctured code rate is optimized so that the average delay is minimized. The coding gain in terms of the message delay is also defined. Since using punctured convolutional code with interleaving is still inadequate to combat the severe fading for short packets, the use of multiple copies of assignment and acknowledgment packets is suggested. The performance on the average end-to-end delay of this protocol is analyzed. It is shown that a replication of three copies for both assignment packets and acknowledgment packets is optimum for the cases considered.

Application of a personal computer for the uncoupled vibration analysis of wind turbine blade and counterweight assemblies

NASA Technical Reports Server (NTRS)

White, P. R.; Little, R. R.

1985-01-01

A research effort was undertaken to develop personal computer based software for vibrational analysis. The software was developed to analytically determine the natural frequencies and mode shapes for the uncoupled lateral vibrations of the blade and counterweight assemblies used in a single bladed wind turbine. The uncoupled vibration analysis was performed in both the flapwise and chordwise directions for static rotor conditions. The effects of rotation on the uncoupled flapwise vibration of the blade and counterweight assemblies were evaluated for various rotor speeds up to 90 rpm. The theory, used in the vibration analysis codes, is based on a lumped mass formulation for the blade and counterweight assemblies. The codes are general so that other designs can be readily analyzed. The input for the codes is generally interactive to facilitate usage. The output of the codes is both tabular and graphical. Listings of the codes are provided. Predicted natural frequencies of the first several modes show reasonable agreement with experimental results. The analysis codes were originally developed on a DEC PDP 11/34 minicomputer and then downloaded and modified to run on an ITT XTRA personal computer. Studies conducted to evaluate the efficiency of running the programs on a personal computer as compared with the minicomputer indicated that, with the proper combination of hardware and software options, the efficiency of using a personal computer exceeds that of a minicomputer.

Analysis of the Length of Braille Texts in English Braille American Edition, the Nemeth Code, and Computer Braille Code versus the Unified English Braille Code

ERIC Educational Resources Information Center

Knowlton, Marie; Wetzel, Robin

2006-01-01

This study compared the length of text in English Braille American Edition, the Nemeth code, and the computer braille code with the Unified English Braille Code (UEBC)--also known as Unified English Braille (UEB). The findings indicate that differences in the length of text are dependent on the type of material that is transcribed and the grade…

Permanence analysis of a concatenated coding scheme for error control

NASA Technical Reports Server (NTRS)

Costello, D. J., Jr.; Lin, S.; Kasami, T.

1983-01-01

A concatenated coding scheme for error control in data communications is analyzed. In this scheme, the inner code is used for both error correction and detection, however, the outer code is used only for error detection. A retransmission is requested if the outer code detects the presence of errors after the inner code decoding. Probability of undetected error is derived and bounded. A particular example, proposed for the planetary program, is analyzed.

Digital microarray analysis for digital artifact genomics

NASA Astrophysics Data System (ADS)

Jaenisch, Holger; Handley, James; Williams, Deborah

2013-06-01

We implement a Spatial Voting (SV) based analogy of microarray analysis for digital gene marker identification in malware code sections. We examine a famous set of malware formally analyzed by Mandiant and code named Advanced Persistent Threat (APT1). APT1 is a Chinese organization formed with specific intent to infiltrate and exploit US resources. Manidant provided a detailed behavior and sting analysis report for the 288 malware samples available. We performed an independent analysis using a new alternative to the traditional dynamic analysis and static analysis we call Spatial Analysis (SA). We perform unsupervised SA on the APT1 originating malware code sections and report our findings. We also show the results of SA performed on some members of the families associated by Manidant. We conclude that SV based SA is a practical fast alternative to dynamics analysis and static analysis.

On the Use of Statistics in Design and the Implications for Deterministic Computer Experiments

NASA Technical Reports Server (NTRS)

Simpson, Timothy W.; Peplinski, Jesse; Koch, Patrick N.; Allen, Janet K.

1997-01-01

Perhaps the most prevalent use of statistics in engineering design is through Taguchi's parameter and robust design -- using orthogonal arrays to compute signal-to-noise ratios in a process of design improvement. In our view, however, there is an equally exciting use of statistics in design that could become just as prevalent: it is the concept of metamodeling whereby statistical models are built to approximate detailed computer analysis codes. Although computers continue to get faster, analysis codes always seem to keep pace so that their computational time remains non-trivial. Through metamodeling, approximations of these codes are built that are orders of magnitude cheaper to run. These metamodels can then be linked to optimization routines for fast analysis, or they can serve as a bridge for integrating analysis codes across different domains. In this paper we first review metamodeling techniques that encompass design of experiments, response surface methodology, Taguchi methods, neural networks, inductive learning, and kriging. We discuss their existing applications in engineering design and then address the dangers of applying traditional statistical techniques to approximate deterministic computer analysis codes. We conclude with recommendations for the appropriate use of metamodeling techniques in given situations and how common pitfalls can be avoided.

Committed to the Honor Code: An Investment Model Analysis of Academic Integrity

ERIC Educational Resources Information Center

Dix, Emily L.; Emery, Lydia F.; Le, Benjamin

2014-01-01

Educators worldwide face challenges surrounding academic integrity. The development of honor codes can promote academic integrity, but understanding how and why honor codes affect behavior is critical to their successful implementation. To date, research has not examined how students' "relationship" to an honor code predicts…

One Speaker, Two Languages. Cross-Disciplinary Perspectives on Code-Switching.

ERIC Educational Resources Information Center

Milroy, Lesley, Ed.; Muysken, Pieter, Ed.

Fifteen articles review code-switching in the four major areas: policy implications in specific institutional and community settings; perspectives of social theory of code-switching as a form of speech behavior in particular social contexts; the grammatical analysis of code-switching, including factors that constrain switching even within a…

User's Guide for MSAP2D: A Program for Unsteady Aerodynamic and Aeroelastic (Flutter and Forced Response) Analysis of Multistage Compressors and Turbines. 1.0

NASA Technical Reports Server (NTRS)

Reddy, T. S. R.; Srivastava, R.

1996-01-01

This guide describes the input data required for using MSAP2D (Multi Stage Aeroelastic analysis Program - Two Dimensional) computer code. MSAP2D can be used for steady, unsteady aerodynamic, and aeroelastic (flutter and forced response) analysis of bladed disks arranged in multiple blade rows such as those found in compressors, turbines, counter rotating propellers or propfans. The code can also be run for single blade row. MSAP2D code is an extension of the original NPHASE code for multiblade row aerodynamic and aeroelastic analysis. Euler equations are used to obtain aerodynamic forces. The structural dynamic equations are written for a rigid typical section undergoing pitching (torsion) and plunging (bending) motion. The aeroelastic equations are solved in time domain. For single blade row analysis, frequency domain analysis is also provided to obtain unsteady aerodynamic coefficients required in an eigen analysis for flutter. In this manual, sample input and output are provided for a single blade row example, two blade row example with equal and unequal number of blades in the blade rows.

Probabilistic structural analysis methods for select space propulsion system components

NASA Technical Reports Server (NTRS)

Millwater, H. R.; Cruse, T. A.

1989-01-01

The Probabilistic Structural Analysis Methods (PSAM) project developed at the Southwest Research Institute integrates state-of-the-art structural analysis techniques with probability theory for the design and analysis of complex large-scale engineering structures. An advanced efficient software system (NESSUS) capable of performing complex probabilistic analysis has been developed. NESSUS contains a number of software components to perform probabilistic analysis of structures. These components include: an expert system, a probabilistic finite element code, a probabilistic boundary element code and a fast probability integrator. The NESSUS software system is shown. An expert system is included to capture and utilize PSAM knowledge and experience. NESSUS/EXPERT is an interactive menu-driven expert system that provides information to assist in the use of the probabilistic finite element code NESSUS/FEM and the fast probability integrator (FPI). The expert system menu structure is summarized. The NESSUS system contains a state-of-the-art nonlinear probabilistic finite element code, NESSUS/FEM, to determine the structural response and sensitivities. A broad range of analysis capabilities and an extensive element library is present.

Optical Surface Analysis Code (OSAC). 7.0

NASA Technical Reports Server (NTRS)

Glenn, P.

1998-01-01

The purpose of this modification to the Optical Surface Analysis Code (OSAC) is to upgrade the PSF program to allow the user to get proper diffracted energy normalization even when deliberately obscuring rays with internal obscurations.

LSENS, The NASA Lewis Kinetics and Sensitivity Analysis Code

NASA Technical Reports Server (NTRS)

Radhakrishnan, K.

2000-01-01

A general chemical kinetics and sensitivity analysis code for complex, homogeneous, gas-phase reactions is described. The main features of the code, LSENS (the NASA Lewis kinetics and sensitivity analysis code), are its flexibility, efficiency and convenience in treating many different chemical reaction models. The models include: static system; steady, one-dimensional, inviscid flow; incident-shock initiated reaction in a shock tube; and a perfectly stirred reactor. In addition, equilibrium computations can be performed for several assigned states. An implicit numerical integration method (LSODE, the Livermore Solver for Ordinary Differential Equations), which works efficiently for the extremes of very fast and very slow reactions, is used to solve the "stiff" ordinary differential equation systems that arise in chemical kinetics. For static reactions, the code uses the decoupled direct method to calculate sensitivity coefficients of the dependent variables and their temporal derivatives with respect to the initial values of dependent variables and/or the rate coefficient parameters. Solution methods for the equilibrium and post-shock conditions and for perfectly stirred reactor problems are either adapted from or based on the procedures built into the NASA code CEA (Chemical Equilibrium and Applications).

Main steam line break accident simulation of APR1400 using the model of ATLAS facility

NASA Astrophysics Data System (ADS)

Ekariansyah, A. S.; Deswandri; Sunaryo, Geni R.

2018-02-01

A main steam line break simulation for APR1400 as an advanced design of PWR has been performed using the RELAP5 code. The simulation was conducted in a model of thermal-hydraulic test facility called as ATLAS, which represents a scaled down facility of the APR1400 design. The main steam line break event is described in a open-access safety report document, in which initial conditions and assumptionsfor the analysis were utilized in performing the simulation and analysis of the selected parameter. The objective of this work was to conduct a benchmark activities by comparing the simulation results of the CESEC-III code as a conservative approach code with the results of RELAP5 as a best-estimate code. Based on the simulation results, a general similarity in the behavior of selected parameters was observed between the two codes. However the degree of accuracy still needs further research an analysis by comparing with the other best-estimate code. Uncertainties arising from the ATLAS model should be minimized by taking into account much more specific data in developing the APR1400 model.

Full core analysis of IRIS reactor by using MCNPX.

PubMed

Amin, E A; Bashter, I I; Hassan, Nabil M; Mustafa, S S

2016-07-01

This paper describes neutronic analysis for fresh fuelled IRIS (International Reactor Innovative and Secure) reactor by MCNPX code. The analysis included criticality calculations, radial power and axial power distribution, nuclear peaking factor and axial offset percent at the beginning of fuel cycle. The effective multiplication factor obtained by MCNPX code is compared with previous calculations by HELIOS/NESTLE, CASMO/SIMULATE, modified CORD-2 nodal calculations and SAS2H/KENO-V code systems. It is found that k-eff value obtained by MCNPX is closer to CORD-2 value. The radial and axial powers are compared with other published results carried out using SAS2H/KENO-V code. Moreover, the WIMS-D5 code is used for studying the effect of enriched boron in form of ZrB2 on the effective multiplication factor (K-eff) of the fuel pin. In this part of calculation, K-eff is calculated at different concentrations of Boron-10 in mg/cm at different stages of burnup of unit cell. The results of this part are compared with published results performed by HELIOS code. Copyright © 2016 Elsevier Ltd. All rights reserved.

Analysis of SMA Hybrid Composite Structures using Commercial Codes

NASA Technical Reports Server (NTRS)

Turner, Travis L.; Patel, Hemant D.

2004-01-01

A thermomechanical model for shape memory alloy (SMA) actuators and SMA hybrid composite (SMAHC) structures has been recently implemented in the commercial finite element codes MSC.Nastran and ABAQUS. The model may be easily implemented in any code that has the capability for analysis of laminated composite structures with temperature dependent material properties. The model is also relatively easy to use and requires input of only fundamental engineering properties. A brief description of the model is presented, followed by discussion of implementation and usage in the commercial codes. Results are presented from static and dynamic analysis of SMAHC beams of two types; a beam clamped at each end and a cantilevered beam. Nonlinear static (post-buckling) and random response analyses are demonstrated for the first specimen. Static deflection (shape) control is demonstrated for the cantilevered beam. Approaches for modeling SMAHC material systems with embedded SMA in ribbon and small round wire product forms are demonstrated and compared. The results from the commercial codes are compared to those from a research code as validation of the commercial implementations; excellent correlation is achieved in all cases.

Spectral fitting, shock layer modeling, and production of nitrogen oxides and excited nitrogen

NASA Technical Reports Server (NTRS)

Blackwell, H. E.

1991-01-01

An analysis was made of N2 emission from 8.72 MJ/kg shock layer at 2.54, 1.91, and 1.27 cm positions and vibrational state distributions, temperatures, and relative electronic state populations was obtained from data sets. Other recorded arc jet N2 and air spectral data were reviewed and NO emission characteristics were studied. A review of operational procedures of the DSMC code was made. Information on other appropriate codes and modifications, including ionization, were made as well as a determination of the applicability of codes reviewed to task requirement. A review was also made of computational procedures used in CFD codes of Li and other codes on JSC computers. An analysis was made of problems associated with integration of specific chemical kinetics applicable to task into CFD codes.

Thermodynamic Analysis of the Combustion of Metallic Materials

NASA Technical Reports Server (NTRS)

Wilson, D. Bruce; Stoltzfus, Joel M.

2000-01-01

Two types of computer codes are available to assist in the thermodynamic analysis of metallic materials combustion. One type of code calculates phase equilibrium data and is represented by CALPHAD. The other type of code calculates chemical reaction by the Gordon-McBride code. The first has seen significant application for alloy-phase diagrams, but only recently has it been considered for oxidation systems. The Gordon-McBride code has been applied to the combustion of metallic materials. Both codes are limited by their treatment of non-ideal solutions and the fact they are limited to treating volatile and gaseous species as ideal. This paper examines the significance of these limitations for combustion of metallic materials. In addition, the applicability of linear-free energy relationships for solid-phase oxidation and their possible extension to liquid-phase systems is examined.

[Differentiation of coding quality in orthopaedics by special, illustration-oriented case group analysis in the G-DRG System 2005].

PubMed

Schütz, U; Reichel, H; Dreinhöfer, K

2007-01-01

We introduce a grouping system for clinical practice which allows the separation of DRG coding in specific orthopaedic groups based on anatomic regions, operative procedures, therapeutic interventions and morbidity equivalent diagnosis groups. With this, a differentiated aim-oriented analysis of illustrated internal DRG data becomes possible. The group-specific difference of the coding quality between the DRG groups following primary coding by the orthopaedic surgeon and final coding by the medical controlling is analysed. In a consecutive series of 1600 patients parallel documentation and group-specific comparison of the relevant DRG parameters were carried out in every case after primary and final coding. Analysing the group-specific share in the additional CaseMix coding, the group "spine surgery" dominated, closely followed by the groups "arthroplasty" and "surgery due to infection, tumours, diabetes". Altogether, additional cost-weight-relevant coding was necessary most frequently in the latter group (84%), followed by group "spine surgery" (65%). In DRGs representing conservative orthopaedic treatment documented procedures had nearly no influence on the cost weight. The introduced system of case group analysis in internal DRG documentation can lead to the detection of specific problems in primary coding and cost-weight relevant changes of the case mix. As an instrument for internal process control in the orthopaedic field, it can serve as a communicative interface between an economically oriented classification of the hospital performance and a specific problem solution of the medical staff involved in the department management.

General Electromagnetic Model for the Analysis of Complex Systems (GEMACS) Computer Code Documentation (Version 3). Volume 3, Part 4.

DTIC Science & Technology

1983-09-01

6ENFRAL. ELECTROMAGNETIC MODEL FOR THE ANALYSIS OF COMPLEX SYSTEMS **%(GEMA CS) Computer Code Documentation ii( Version 3 ). A the BDM Corporation Dr...ANALYSIS FnlTcnclRpr F COMPLEX SYSTEM (GmCS) February 81 - July 83- I TR CODE DOCUMENTATION (Version 3 ) 6.PROMN N.REPORT NUMBER 5. CONTRACT ORGAT97...the ti and t2 directions on the source patch. 3 . METHOD: The electric field at a segment observation point due to the source patch j is given by 1-- lnA

Transient Ejector Analysis (TEA) code user's guide

NASA Technical Reports Server (NTRS)

Drummond, Colin K.

1993-01-01

A FORTRAN computer program for the semi analytic prediction of unsteady thrust augmenting ejector performance has been developed, based on a theoretical analysis for ejectors. That analysis blends classic self-similar turbulent jet descriptions with control-volume mixing region elements. Division of the ejector into an inlet, diffuser, and mixing region allowed flexibility in the modeling of the physics for each region. In particular, the inlet and diffuser analyses are simplified by a quasi-steady-analysis, justified by the assumption that pressure is the forcing function in those regions. Only the mixing region is assumed to be dominated by viscous effects. The present work provides an overview of the code structure, a description of the required input and output data file formats, and the results for a test case. Since there are limitations to the code for applications outside the bounds of the test case, the user should consider TEA as a research code (not as a production code), designed specifically as an implementation of the proposed ejector theory. Program error flags are discussed, and some diagnostic routines are presented.

Classification of breast tissue in mammograms using efficient coding.

PubMed

Costa, Daniel D; Campos, Lúcio F; Barros, Allan K

2011-06-24

Female breast cancer is the major cause of death by cancer in western countries. Efforts in Computer Vision have been made in order to improve the diagnostic accuracy by radiologists. Some methods of lesion diagnosis in mammogram images were developed based in the technique of principal component analysis which has been used in efficient coding of signals and 2D Gabor wavelets used for computer vision applications and modeling biological vision. In this work, we present a methodology that uses efficient coding along with linear discriminant analysis to distinguish between mass and non-mass from 5090 region of interest from mammograms. The results show that the best rates of success reached with Gabor wavelets and principal component analysis were 85.28% and 87.28%, respectively. In comparison, the model of efficient coding presented here reached up to 90.07%. Altogether, the results presented demonstrate that independent component analysis performed successfully the efficient coding in order to discriminate mass from non-mass tissues. In addition, we have observed that LDA with ICA bases showed high predictive performance for some datasets and thus provide significant support for a more detailed clinical investigation.

Probabilistic Structural Analysis Methods (PSAM) for select space propulsion systems components

NASA Technical Reports Server (NTRS)

1991-01-01

Summarized here is the technical effort and computer code developed during the five year duration of the program for probabilistic structural analysis methods. The summary includes a brief description of the computer code manuals and a detailed description of code validation demonstration cases for random vibrations of a discharge duct, probabilistic material nonlinearities of a liquid oxygen post, and probabilistic buckling of a transfer tube liner.

HART-II: Prediction of Blade-Vortex Interaction Loading

DTIC Science & Technology

2003-09-01

14:30 (2) Improvement of DLR Rotor Aero- acoustic Code ( APSIM ) and its Valida- tion with Analytic Solution J. Yin, J. Delfs (5...of DLR Rotor Aero- acoustic Code ( APSIM ) and its Valida- tion with Analytic Solution J. Yin, J. Delfs (5) Aeroelastic Stability Analysis of...of DLR Rotor Aero- acoustic Code ( APSIM ) and its Valida- tion with Analytic Solution J. Yin, J. Delfs (5) Aeroelastic Stability Analysis of

Safe, Multiphase Bounds Check Elimination in Java

DTIC Science & Technology

2010-01-28

production of mobile code from source code, JIT compilation in the virtual ma- chine, and application code execution. The code producer uses...invariants, and inequality constraint analysis) to identify and prove redundancy of bounds checks. During class-loading and JIT compilation, the virtual...unoptimized code if the speculated invariants do not hold. The combined effect of the multiple phases is to shift the effort as- sociated with bounds

CELFE/NASTRAN Code for the Analysis of Structures Subjected to High Velocity Impact

NASA Technical Reports Server (NTRS)

Chamis, C. C.

1978-01-01

CELFE (Coupled Eulerian Lagrangian Finite Element)/NASTRAN Code three-dimensional finite element code has the capability for analyzing of structures subjected to high velocity impact. The local response is predicted by CELFE and, for large problems, the far-field impact response is predicted by NASTRAN. The coupling of the CELFE code with NASTRAN (CELFE/NASTRAN code) and the application of the code to selected three-dimensional high velocity impact problems are described.

Structural design, analysis, and code evaluation of an odd-shaped pressure vessel

NASA Astrophysics Data System (ADS)

Rezvani, M. A.; Ziada, H. H.

1992-12-01

An effort to design, analyze, and evaluate a rectangular pressure vessel is described. Normally pressure vessels are designed in circular or spherical shapes to prevent stress concentrations. In this case, because of operational limitations, the choice of vessels was limited to a rectangular pressure box with a removable cover plate. The American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code is used as a guideline for pressure containments whose width or depth exceeds 15.24 cm (6.0 in.) and where pressures will exceed 103.4 KPa (15.0 lbf/in(sup 2)). This evaluation used Section 8 of this Code, hereafter referred to as the Code. The dimensions and working pressure of the subject vessel fall within the pressure vessel category of the Code. The Code design guidelines and rules do not directly apply to this vessel. Therefore, finite-element methodology was used to analyze the pressure vessel, and the Code then was used in qualifying the vessel to be stamped to the Code. Section 8, Division 1 of the Code was used for evaluation. This action was justified by selecting a material for which fatigue damage would not be a concern. The stress analysis results were then checked against the Code, and the thicknesses adjusted to satisfy Code requirements. Although not directly applicable, the Code design formulas for rectangular vessels were also considered and presented.

ICC-CLASS: isotopically-coded cleavable crosslinking analysis software suite

PubMed Central

2010-01-01

Background Successful application of crosslinking combined with mass spectrometry for studying proteins and protein complexes requires specifically-designed crosslinking reagents, experimental techniques, and data analysis software. Using isotopically-coded ("heavy and light") versions of the crosslinker and cleavable crosslinking reagents is analytically advantageous for mass spectrometric applications and provides a "handle" that can be used to distinguish crosslinked peptides of different types, and to increase the confidence of the identification of the crosslinks. Results Here, we describe a program suite designed for the analysis of mass spectrometric data obtained with isotopically-coded cleavable crosslinkers. The suite contains three programs called: DX, DXDX, and DXMSMS. DX searches the mass spectra for the presence of ion signal doublets resulting from the light and heavy isotopic forms of the isotopically-coded crosslinking reagent used. DXDX searches for possible mass matches between cleaved and uncleaved isotopically-coded crosslinks based on the established chemistry of the cleavage reaction for a given crosslinking reagent. DXMSMS assigns the crosslinks to the known protein sequences, based on the isotopically-coded and un-coded MS/MS fragmentation data of uncleaved and cleaved peptide crosslinks. Conclusion The combination of these three programs, which are tailored to the analytical features of the specific isotopically-coded cleavable crosslinking reagents used, represents a powerful software tool for automated high-accuracy peptide crosslink identification. See: http://www.creativemolecules.com/CM_Software.htm PMID:20109223

The harder they fall? Sex and race/ethnic specific suicide rates in the U.S. foreclosure crisis.

PubMed

Houle, Jason N; Light, Michael T

2017-05-01

Previous work shows suicide rates increase during economic recessions, but little research has examined the extent to which the foreclosure crisis-a unique aspect of the Great Recession-has contributed to disparities in rising suicide rates by race and sex. We develop and test two competing hypotheses regarding the association between foreclosures and race by sex specific suicide rates. We link foreclosure data (RealtyTrac) and suicide data (CDC) from 174 metropolitan areas from 2005 to 2010 (1044 MSA-year observations) and find that-net of time invariant unobserved between-metro area differences, national time trends, and time-varying confounders-a rise in the foreclosure rate is associated with a marginal increase in suicide, but this main effect masks considerable heterogeneity across groups. The association is particularly strong for white males, and weaker or non-existent for other race by sex groups. Copyright © 2017 Elsevier Ltd. All rights reserved.

Setting new thermal standards for transitional and coastal (TraC) waters.

PubMed

Wither, Andrew; Bamber, Roger; Colclough, Steve; Dyer, Keith; Elliott, Mike; Holmes, Peter; Jenner, Henk; Taylor, Colin; Turnpenny, Andy

2012-08-01

The construction of a new generation of coastal power stations in the UK and other western European countries has highlighted the absence of robust standards for thermal discharges to transitional and coastal waters. The proposed discharge volumes are greater than hitherto, yet there has been little independent critical examination of their potential impact, whilst much of the existing guidance has been adapted from freshwater practice. This review considers the available knowledge on the tolerance and behaviour of fish and other marine biota to heated effluents. Appropriate ways are suggested of grouping fish species to reflect their sensitivity to thermal effects. The plethora of existing standards are considered and their validity assessed in a framework of predicted seawater temperature rise. Those species or groups of organisms most likely to be affected are identified and finally specific recommendations for thermal standards consistent with long term sustainability are proposed. Copyright © 2012 Elsevier Ltd. All rights reserved.

Characterization of Micrococcaceae strains isolated from the human urogenital tract by the conventional scheme and a micromethod.

PubMed

Baldellon, C; Mégraud, F

1985-03-01

Two hundred and twelve Micrococcaceae isolates were obtained from 82 men with nongonococcal urethritis, 24 women with vaginitis, and 54 girls with vulvovaginitis. Identification and biotyping of these strains were carried out by using the simplified scheme of Kloos and Schleifer (W. E. Kloos and K. H. Schleifer, J. Clin. Microbiol. 1:82-88, 1975) and the commercially available API Staph test (DMS Staph Trac). Staphylococcus epidermidis occurred in about half of these isolates. There was no statistical difference between the urethral and vaginal specimens, except for S. haemolyticus found primarily in males and for S. simulans and S. aureus found primarily in girls between the ages of 1 and 12 years. S. saprophyticus, a major cause of urinary tract infections in young women, was never isolated from the vagina, suggesting the probability of another reservoir.

Analyses of 1/15 scale Creare bypass transient experiments. [PWR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kmetyk, L.N.; Buxton, L.D.; Cole, R.K. Jr.

1982-09-01

RELAP4 analyses of several 1/15 scale Creare H-series bypass transient experiments have been done to investigate the effect of using different downcomer nodalizations, physical scales, slip models, and vapor fraction donoring methods. Most of the analyses were thermal equilibrium calculations performed with RELAP4/MOD5, but a few such calculations were done with RELAP4/MOD6 and RELAP4/MOD7, which contain improved slip models. In order to estimate the importance of nonequilibrium effects, additional analyses were performed with TRAC-PD2, RELAP5 and the nonequilibrium option of RELAP4/MOD7. The purpose of these studies was to determine whether results from Westinghouse's calculation of the Creare experiments, which weremore » done with a UHI-modified version of SATAN, were sufficient to guarantee SATAN would be conservative with respect to ECC bypass in full-scale plant analyses.« less

Tracking accuracy assessment for concentrator photovoltaic systems

NASA Astrophysics Data System (ADS)

Norton, Matthew S. H.; Anstey, Ben; Bentley, Roger W.; Georghiou, George E.

2010-10-01

The accuracy to which a concentrator photovoltaic (CPV) system can track the sun is an important parameter that influences a number of measurements that indicate the performance efficiency of the system. This paper presents work carried out into determining the tracking accuracy of a CPV system, and illustrates the steps involved in gaining an understanding of the tracking accuracy. A Trac-Stat SL1 accuracy monitor has been used in the determination of pointing accuracy and has been integrated into the outdoor CPV module test facility at the Photovoltaic Technology Laboratories in Nicosia, Cyprus. Results from this work are provided to demonstrate how important performance indicators may be presented, and how the reliability of results is improved through the deployment of such accuracy monitors. Finally, recommendations on the use of such sensors are provided as a means to improve the interpretation of real outdoor performance.

Evaluation of the finite element fuel rod analysis code (FRANCO)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, K.; Feltus, M.A.

1994-12-31

Knowledge of temperature distribution in a nuclear fuel rod is required to predict the behavior of fuel elements during operating conditions. The thermal and mechanical properties and performance characteristics are strongly dependent on the temperature, which can vary greatly inside the fuel rod. A detailed model of fuel rod behavior can be described by various numerical methods, including the finite element approach. The finite element method has been successfully used in many engineering applications, including nuclear piping and reactor component analysis. However, fuel pin analysis has traditionally been carried out with finite difference codes, with the exception of Electric Powermore » Research Institute`s FREY code, which was developed for mainframe execution. This report describes FRANCO, a finite element fuel rod analysis code capable of computing temperature disrtibution and mechanical deformation of a single light water reactor fuel rod.« less

Computational electronics and electromagnetics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shang, C. C.

The Computational Electronics and Electromagnetics thrust area at Lawrence Livermore National Laboratory serves as the focal point for engineering R&D activities for developing computer-based design, analysis, and tools for theory. Key representative applications include design of particle accelerator cells and beamline components; engineering analysis and design of high-power components, photonics, and optoelectronics circuit design; EMI susceptibility analysis; and antenna synthesis. The FY-96 technology-base effort focused code development on (1) accelerator design codes; (2) 3-D massively parallel, object-oriented time-domain EM codes; (3) material models; (4) coupling and application of engineering tools for analysis and design of high-power components; (5) 3-D spectral-domainmore » CEM tools; and (6) enhancement of laser drilling codes. Joint efforts with the Power Conversion Technologies thrust area include development of antenna systems for compact, high-performance radar, in addition to novel, compact Marx generators. 18 refs., 25 figs., 1 tab.« less

Parallel-vector computation for linear structural analysis and non-linear unconstrained optimization problems

NASA Technical Reports Server (NTRS)

Nguyen, D. T.; Al-Nasra, M.; Zhang, Y.; Baddourah, M. A.; Agarwal, T. K.; Storaasli, O. O.; Carmona, E. A.

1991-01-01

Several parallel-vector computational improvements to the unconstrained optimization procedure are described which speed up the structural analysis-synthesis process. A fast parallel-vector Choleski-based equation solver, pvsolve, is incorporated into the well-known SAP-4 general-purpose finite-element code. The new code, denoted PV-SAP, is tested for static structural analysis. Initial results on a four processor CRAY 2 show that using pvsolve reduces the equation solution time by a factor of 14-16 over the original SAP-4 code. In addition, parallel-vector procedures for the Golden Block Search technique and the BFGS method are developed and tested for nonlinear unconstrained optimization. A parallel version of an iterative solver and the pvsolve direct solver are incorporated into the BFGS method. Preliminary results on nonlinear unconstrained optimization test problems, using pvsolve in the analysis, show excellent parallel-vector performance indicating that these parallel-vector algorithms can be used in a new generation of finite-element based structural design/analysis-synthesis codes.

Toward Intelligent Software Defect Detection

NASA Technical Reports Server (NTRS)

Benson, Markland J.

2011-01-01

Source code level software defect detection has gone from state of the art to a software engineering best practice. Automated code analysis tools streamline many of the aspects of formal code inspections but have the drawback of being difficult to construct and either prone to false positives or severely limited in the set of defects that can be detected. Machine learning technology provides the promise of learning software defects by example, easing construction of detectors and broadening the range of defects that can be found. Pinpointing software defects with the same level of granularity as prominent source code analysis tools distinguishes this research from past efforts, which focused on analyzing software engineering metrics data with granularity limited to that of a particular function rather than a line of code.

Multiphysics Code Demonstrated for Propulsion Applications

NASA Technical Reports Server (NTRS)

Lawrence, Charles; Melis, Matthew E.

1998-01-01

The utility of multidisciplinary analysis tools for aeropropulsion applications is being investigated at the NASA Lewis Research Center. The goal of this project is to apply Spectrum, a multiphysics code developed by Centric Engineering Systems, Inc., to simulate multidisciplinary effects in turbomachinery components. Many engineering problems today involve detailed computer analyses to predict the thermal, aerodynamic, and structural response of a mechanical system as it undergoes service loading. Analysis of aerospace structures generally requires attention in all three disciplinary areas to adequately predict component service behavior, and in many cases, the results from one discipline substantially affect the outcome of the other two. There are numerous computer codes currently available in the engineering community to perform such analyses in each of these disciplines. Many of these codes are developed and used in-house by a given organization, and many are commercially available. However, few, if any, of these codes are designed specifically for multidisciplinary analyses. The Spectrum code has been developed for performing fully coupled fluid, thermal, and structural analyses on a mechanical system with a single simulation that accounts for all simultaneous interactions, thus eliminating the requirement for running a large number of sequential, separate, disciplinary analyses. The Spectrum code has a true multiphysics analysis capability, which improves analysis efficiency as well as accuracy. Centric Engineering, Inc., working with a team of Lewis and AlliedSignal Engines engineers, has been evaluating Spectrum for a variety of propulsion applications including disk quenching, drum cavity flow, aeromechanical simulations, and a centrifugal compressor flow simulation.

Learning to Analyze and Code Accounting Transactions in Interactive Mode.

ERIC Educational Resources Information Center

Bentz, William F.; Ambler, Eric E.

An interactive computer-assisted instructional (CAI) system, called CODE, is used to teach transactional analysis, or coding, in elementary accounting. The first major component of CODE is TEACH, a program which controls student input and output. Following the statement of a financial position on a cathode ray tube, TEACH describes an event to…

Porcupine: A visual pipeline tool for neuroimaging analysis

PubMed Central

Snoek, Lukas; Knapen, Tomas

2018-01-01

The field of neuroimaging is rapidly adopting a more reproducible approach to data acquisition and analysis. Data structures and formats are being standardised and data analyses are getting more automated. However, as data analysis becomes more complicated, researchers often have to write longer analysis scripts, spanning different tools across multiple programming languages. This makes it more difficult to share or recreate code, reducing the reproducibility of the analysis. We present a tool, Porcupine, that constructs one’s analysis visually and automatically produces analysis code. The graphical representation improves understanding of the performed analysis, while retaining the flexibility of modifying the produced code manually to custom needs. Not only does Porcupine produce the analysis code, it also creates a shareable environment for running the code in the form of a Docker image. Together, this forms a reproducible way of constructing, visualising and sharing one’s analysis. Currently, Porcupine links to Nipype functionalities, which in turn accesses most standard neuroimaging analysis tools. Our goal is to release researchers from the constraints of specific implementation details, thereby freeing them to think about novel and creative ways to solve a given problem. Porcupine improves the overview researchers have of their processing pipelines, and facilitates both the development and communication of their work. This will reduce the threshold at which less expert users can generate reusable pipelines. With Porcupine, we bridge the gap between a conceptual and an implementational level of analysis and make it easier for researchers to create reproducible and shareable science. We provide a wide range of examples and documentation, as well as installer files for all platforms on our website: https://timvanmourik.github.io/Porcupine. Porcupine is free, open source, and released under the GNU General Public License v3.0. PMID:29746461

Recent improvements of reactor physics codes in MHI

NASA Astrophysics Data System (ADS)

Kosaka, Shinya; Yamaji, Kazuya; Kirimura, Kazuki; Kamiyama, Yohei; Matsumoto, Hideki

2015-12-01

This paper introduces recent improvements for reactor physics codes in Mitsubishi Heavy Industries, Ltd(MHI). MHI has developed a new neutronics design code system Galaxy/Cosmo-S(GCS) for PWR core analysis. After TEPCO's Fukushima Daiichi accident, it is required to consider design extended condition which has not been covered explicitly by the former safety licensing analyses. Under these circumstances, MHI made some improvements for GCS code system. A new resonance calculation model of lattice physics code and homogeneous cross section representative model for core simulator have been developed to apply more wide range core conditions corresponding to severe accident status such like anticipated transient without scram (ATWS) analysis and criticality evaluation of dried-up spent fuel pit. As a result of these improvements, GCS code system has very wide calculation applicability with good accuracy for any core conditions as far as fuel is not damaged. In this paper, the outline of GCS code system is described briefly and recent relevant development activities are presented.

Radiant Energy Measurements from a Scaled Jet Engine Axisymmetric Exhaust Nozzle for a Baseline Code Validation Case

NASA Technical Reports Server (NTRS)

Baumeister, Joseph F.

1994-01-01

A non-flowing, electrically heated test rig was developed to verify computer codes that calculate radiant energy propagation from nozzle geometries that represent aircraft propulsion nozzle systems. Since there are a variety of analysis tools used to evaluate thermal radiation propagation from partially enclosed nozzle surfaces, an experimental benchmark test case was developed for code comparison. This paper briefly describes the nozzle test rig and the developed analytical nozzle geometry used to compare the experimental and predicted thermal radiation results. A major objective of this effort was to make available the experimental results and the analytical model in a format to facilitate conversion to existing computer code formats. For code validation purposes this nozzle geometry represents one validation case for one set of analysis conditions. Since each computer code has advantages and disadvantages based on scope, requirements, and desired accuracy, the usefulness of this single nozzle baseline validation case can be limited for some code comparisons.

Recent improvements of reactor physics codes in MHI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kosaka, Shinya, E-mail: shinya-kosaka@mhi.co.jp; Yamaji, Kazuya; Kirimura, Kazuki

2015-12-31

This paper introduces recent improvements for reactor physics codes in Mitsubishi Heavy Industries, Ltd(MHI). MHI has developed a new neutronics design code system Galaxy/Cosmo-S(GCS) for PWR core analysis. After TEPCO’s Fukushima Daiichi accident, it is required to consider design extended condition which has not been covered explicitly by the former safety licensing analyses. Under these circumstances, MHI made some improvements for GCS code system. A new resonance calculation model of lattice physics code and homogeneous cross section representative model for core simulator have been developed to apply more wide range core conditions corresponding to severe accident status such like anticipatedmore » transient without scram (ATWS) analysis and criticality evaluation of dried-up spent fuel pit. As a result of these improvements, GCS code system has very wide calculation applicability with good accuracy for any core conditions as far as fuel is not damaged. In this paper, the outline of GCS code system is described briefly and recent relevant development activities are presented.« less

NESSUS/NASTRAN Interface

NASA Technical Reports Server (NTRS)

Millwater, Harry; Riha, David

1996-01-01

The NESSUS probabilistic analysis computer program has been developed with a built-in finite element analysis program NESSUS/FEM. However, the NESSUS/FEM program is specialized for engine structures and may not contain sufficient features for other applications. In addition, users often become well acquainted with a particular finite element code and want to use that code for probabilistic structural analysis. For these reasons, this work was undertaken to develop an interface between NESSUS and NASTRAN such that NASTRAN can be used for the finite element analysis and NESSUS can be used for the probabilistic analysis. In addition, NESSUS was restructured such that other finite element codes could be more easily coupled with NESSUS. NESSUS has been enhanced such that NESSUS will modify the NASTRAN input deck for a given set of random variables, run NASTRAN and read the NASTRAN result. The coordination between the two codes is handled automatically. The work described here was implemented within NESSUS 6.2 which was delivered to NASA in September 1995. The code runs on Unix machines: Cray, HP, Sun, SGI and IBM. The new capabilities have been implemented such that a user familiar with NESSUS using NESSUS/FEM and NASTRAN can immediately use NESSUS with NASTRAN. In other words, the interface with NASTRAN has been implemented in an analogous manner to the interface with NESSUS/FEM. Only finite element specific input has been changed. This manual is written as an addendum to the existing NESSUS 6.2 manuals. We assume users have access to NESSUS manuals and are familiar with the operation of NESSUS including probabilistic finite element analysis. Update pages to the NESSUS PFEM manual are contained in Appendix E. The finite element features of the code and the probalistic analysis capabilities are summarized.

A study of transonic aerodynamic analysis methods for use with a hypersonic aircraft synthesis code

NASA Technical Reports Server (NTRS)

Sandlin, Doral R.; Davis, Paul Christopher

1992-01-01

A means of performing routine transonic lift, drag, and moment analyses on hypersonic all-body and wing-body configurations were studied. The analysis method is to be used in conjunction with the Hypersonic Vehicle Optimization Code (HAVOC). A review of existing techniques is presented, after which three methods, chosen to represent a spectrum of capabilities, are tested and the results are compared with experimental data. The three methods consist of a wave drag code, a full potential code, and a Navier-Stokes code. The wave drag code, representing the empirical approach, has very fast CPU times, but very limited and sporadic results. The full potential code provides results which compare favorably to the wind tunnel data, but with a dramatic increase in computational time. Even more extreme is the Navier-Stokes code, which provides the most favorable and complete results, but with a very large turnaround time. The full potential code, TRANAIR, is used for additional analyses, because of the superior results it can provide over empirical and semi-empirical methods, and because of its automated grid generation. TRANAIR analyses include an all body hypersonic cruise configuration and an oblique flying wing supersonic transport.

Fuel burnup analysis for IRIS reactor using MCNPX and WIMS-D5 codes

NASA Astrophysics Data System (ADS)

Amin, E. A.; Bashter, I. I.; Hassan, Nabil M.; Mustafa, S. S.

2017-02-01

International Reactor Innovative and Secure (IRIS) reactor is a compact power reactor designed with especial features. It contains Integral Fuel Burnable Absorber (IFBA). The core is heterogeneous both axially and radially. This work provides the full core burn up analysis for IRIS reactor using MCNPX and WIMDS-D5 codes. Criticality calculations, radial and axial power distributions and nuclear peaking factor at the different stages of burnup were studied. Effective multiplication factor values for the core were estimated by coupling MCNPX code with WIMS-D5 code and compared with SAS2H/KENO-V code values at different stages of burnup. The two calculation codes show good agreement and correlation. The values of radial and axial powers for the full core were also compared with published results given by SAS2H/KENO-V code (at the beginning and end of reactor operation). The behavior of both radial and axial power distribution is quiet similar to the other data published by SAS2H/KENO-V code. The peaking factor values estimated in the present work are close to its values calculated by SAS2H/KENO-V code.

Demonstration of emulator-based Bayesian calibration of safety analysis codes: Theory and formulation

DOE PAGES

Yurko, Joseph P.; Buongiorno, Jacopo; Youngblood, Robert

2015-05-28

System codes for simulation of safety performance of nuclear plants may contain parameters whose values are not known very accurately. New information from tests or operating experience is incorporated into safety codes by a process known as calibration, which reduces uncertainty in the output of the code and thereby improves its support for decision-making. The work reported here implements several improvements on classic calibration techniques afforded by modern analysis techniques. The key innovation has come from development of code surrogate model (or code emulator) construction and prediction algorithms. Use of a fast emulator makes the calibration processes used here withmore » Markov Chain Monte Carlo (MCMC) sampling feasible. This study uses Gaussian Process (GP) based emulators, which have been used previously to emulate computer codes in the nuclear field. The present work describes the formulation of an emulator that incorporates GPs into a factor analysis-type or pattern recognition-type model. This “function factorization” Gaussian Process (FFGP) model allows overcoming limitations present in standard GP emulators, thereby improving both accuracy and speed of the emulator-based calibration process. Calibration of a friction-factor example using a Method of Manufactured Solution is performed to illustrate key properties of the FFGP based process.« less

DRG coding practice: a nationwide hospital survey in Thailand

PubMed Central

2011-01-01

Background Diagnosis Related Group (DRG) payment is preferred by healthcare reform in various countries but its implementation in resource-limited countries has not been fully explored. Objectives This study was aimed (1) to compare the characteristics of hospitals in Thailand that were audited with those that were not and (2) to develop a simplified scale to measure hospital coding practice. Methods A questionnaire survey was conducted of 920 hospitals in the Summary and Coding Audit Database (SCAD hospitals, all of which were audited in 2008 because of suspicious reports of possible DRG miscoding); the questionnaire also included 390 non-SCAD hospitals. The questionnaire asked about general demographics of the hospitals, hospital coding structure and process, and also included a set of 63 opinion-oriented items on the current hospital coding practice. Descriptive statistics and exploratory factor analysis (EFA) were used for data analysis. Results SCAD and Non-SCAD hospitals were different in many aspects, especially the number of medical statisticians, experience of medical statisticians and physicians, as well as number of certified coders. Factor analysis revealed a simplified 3-factor, 20-item model to assess hospital coding practice and classify hospital intention. Conclusion Hospital providers should not be assumed capable of producing high quality DRG codes, especially in resource-limited settings. PMID:22040256

Adaptive Nodal Transport Methods for Reactor Transient Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomas Downar; E. Lewis

2005-08-31

Develop methods for adaptively treating the angular, spatial, and time dependence of the neutron flux in reactor transient analysis. These methods were demonstrated in the DOE transport nodal code VARIANT and the US NRC spatial kinetics code, PARCS.

Aerodynamic Analysis of the M33 Projectile Using the CFX Code

DTIC Science & Technology

2011-12-01

is unlimited 12b. DISTRIBUTION CODE A 13. ABSTRACT (maximum 200 words) The M33 projectile has been analyzed using the ANSYS CFX code that is based...analyzed using the ANSYS CFX code that is based on the numerical solution of the full Navier-Stokes equations. Simulation data were obtained...using the CFX code. The ANSYS - CFX code is a commercial CFD program used to simulate fluid flow in a variety of applications such as gas turbine

VIC: A Computer Analysis of Verbal Interaction Category Systems.

ERIC Educational Resources Information Center

Kline, John A.; And Others

VIC is a computer program for the analysis of verbal interaction category systems, especially the Flanders interaction analysis system. The observer codes verbal behavior on coding sheets for later machine scoring. A matrix is produced by the program showing the number and percentages of times that a particular cell describes classroom behavior.…

Iterative categorization (IC): a systematic technique for analysing qualitative data.

PubMed

Neale, Joanne

2016-06-01

The processes of analysing qualitative data, particularly the stage between coding and publication, are often vague and/or poorly explained within addiction science and research more broadly. A simple but rigorous and transparent technique for analysing qualitative textual data, developed within the field of addiction, is described. The technique, iterative categorization (IC), is suitable for use with inductive and deductive codes and can support a range of common analytical approaches, e.g. thematic analysis, Framework, constant comparison, analytical induction, content analysis, conversational analysis, discourse analysis, interpretative phenomenological analysis and narrative analysis. Once the data have been coded, the only software required is a standard word processing package. Worked examples are provided. © 2016 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction.

Efficiency of International Classification of Diseases, Ninth Revision, Billing Code Searches to Identify Emergency Department Visits for Blood or Body Fluid Exposures through a Statewide Multicenter Database

PubMed Central

Rosen, Lisa M.; Liu, Tao; Merchant, Roland C.

2016-01-01

BACKGROUND Blood and body fluid exposures are frequently evaluated in emergency departments (EDs). However, efficient and effective methods for estimating their incidence are not yet established. OBJECTIVE Evaluate the efficiency and accuracy of estimating statewide ED visits for blood or body fluid exposures using International Classification of Diseases, Ninth Revision (ICD-9), code searches. DESIGN Secondary analysis of a database of ED visits for blood or body fluid exposure. SETTING EDs of 11 civilian hospitals throughout Rhode Island from January 1, 1995, through June 30, 2001. PATIENTS Patients presenting to the ED for possible blood or body fluid exposure were included, as determined by prespecified ICD-9 codes. METHODS Positive predictive values (PPVs) were estimated to determine the ability of 10 ICD-9 codes to distinguish ED visits for blood or body fluid exposure from ED visits that were not for blood or body fluid exposure. Recursive partitioning was used to identify an optimal subset of ICD-9 codes for this purpose. Random-effects logistic regression modeling was used to examine variations in ICD-9 coding practices and styles across hospitals. Cluster analysis was used to assess whether the choice of ICD-9 codes was similar across hospitals. RESULTS The PPV for the original 10 ICD-9 codes was 74.4% (95% confidence interval [CI], 73.2%–75.7%), whereas the recursive partitioning analysis identified a subset of 5 ICD-9 codes with a PPV of 89.9% (95% CI, 88.9%–90.8%) and a misclassification rate of 10.1%. The ability, efficiency, and use of the ICD-9 codes to distinguish types of ED visits varied across hospitals. CONCLUSIONS Although an accurate subset of ICD-9 codes could be identified, variations across hospitals related to hospital coding style, efficiency, and accuracy greatly affected estimates of the number of ED visits for blood or body fluid exposure. PMID:22561713