The trials methodological research agenda: results from a priority setting exercise

PubMed Central

2014-01-01

Background Research into the methods used in the design, conduct, analysis, and reporting of clinical trials is essential to ensure that effective methods are available and that clinical decisions made using results from trials are based on the best available evidence, which is reliable and robust. Methods An on-line Delphi survey of 48 UK Clinical Research Collaboration registered Clinical Trials Units (CTUs) was undertaken. During round one, CTU Directors were asked to identify important topics that require methodological research. During round two, their opinion about the level of importance of each topic was recorded, and during round three, they were asked to review the group’s average opinion and revise their previous opinion if appropriate. Direct reminders were sent to maximise the number of responses at each round. Results are summarised using descriptive methods. Results Forty one (85%) CTU Directors responded to at least one round of the Delphi process: 25 (52%) responded in round one, 32 (67%) responded in round two, 24 (50%) responded in round three. There were only 12 (25%) who responded to all three rounds and 18 (38%) who responded to both rounds two and three. Consensus was achieved amongst CTU Directors that the top three priorities for trials methodological research were ‘Research into methods to boost recruitment in trials’ (considered the highest priority), ‘Methods to minimise attrition’ and ‘Choosing appropriate outcomes to measure’. Fifty other topics were included in the list of priorities and consensus was reached that two topics, ‘Radiotherapy study designs’ and ‘Low carbon trials’, were not priorities. Conclusions This priority setting exercise has identified the research topics felt to be most important to the key stakeholder group of Directors of UKCRC registered CTUs. The use of robust methodology to identify these priorities will help ensure that this work informs the trials methodological research agenda, with a focus on topics that will have most impact and relevance. PMID:24456928

Health economic evaluation: important principles and methodology.

PubMed

Rudmik, Luke; Drummond, Michael

2013-06-01

To discuss health economic evaluation and improve the understanding of common methodology. This article discusses the methodology for the following types of economic evaluations: cost-minimization, cost-effectiveness, cost-utility, cost-benefit, and economic modeling. Topics include health-state utility measures, the quality-adjusted life year (QALY), uncertainty analysis, discounting, decision tree analysis, and Markov modeling. Economic evaluation is the comparative analysis of alternative courses of action in terms of both their costs and consequences. With increasing health care expenditure and limited resources, it is important for physicians to consider the economic impact of their interventions. Understanding common methodology involved in health economic evaluation will improve critical appraisal of the literature and optimize future economic evaluations. Copyright © 2012 The American Laryngological, Rhinological and Otological Society, Inc.

Complex Matrix for the Analysis of Sustainable Transformative Learning: An Assessment Methodology of Sustainability Integration in Universities

ERIC Educational Resources Information Center

Palma, Lisiane Celia; Pedrozo, Eugênio Ávila

2015-01-01

Several papers propose analytical methods relating to the inclusion of sustainability in courses and universities. However, as sustainability is a complex subject, methodological proposals on the topic must avoid making disjointed analyses which focus exclusively on curricula or on organisational strategy, as often seen in the literature.…

The Common Topoi of STEM Discourse: An Apologia and Methodological Proposal, with Pilot Survey

ERIC Educational Resources Information Center

Walsh, Lynda

2010-01-01

In this article, the author proposes a methodology for the rhetorical analysis of scientific, technical, mathematical, and engineering (STEM) discourse based on the common topics (topoi) of this discourse. Beginning with work by Miller, Prelli, and other rhetoricians of STEM discourse--but factoring in related studies in cognitive linguistics--she…

Inconsistency prevents the valuable synergism of explanatory and pragmatic trails.

PubMed

Correia, Luis C L; Correia, Vitor C A; Souza, Thiago M B; Cerqueira, Antonio Maurício S; Alexandre, Felipe K B; Garcia, Guilherme; Ferreira, Felipe R M; Lopes, Fernanda O A

2018-05-01

To assess review articles on pragmatic trials in order to describe how authors define the aim of this type of study, how comprehensive methodological topics are covered, and which topics are most valued by authors. Review articles were selected from Medline Database, based on the expression "pragmatic trial" in the titles. Five trained medical students evaluated the articles, based on a list of 15 self-explanatory methodological topics. Each article was evaluated regarding topics covered. Baseline statements on the aim of pragmatic trials were derived. Among 22 articles identified, there was general agreement that the aim of a pragmatic trial is to evaluate if the intervention works under real-world conditions. The mean number of methodological topics addressed by each article was 7.6 ± 3.1. Only one article covered all 15 topics, three articles (14%) responded to at least 75% of topics and 13 articles (59%) mentioned at least 50% of the topics. The relative frequency each of the 15 topics was cited by articles had a mean of 50% ± 25%. No topic was addressed by all articles, only three (20%) were addressed by more than 75% of articles. There is agreement on the different aims of explanatory and pragmatic trials. But there is a large variation on methodological topics used to define a pragmatic trial, which led to inconsistency in defining the typical methodology of a pragmatic trial. © 2018 Chinese Cochrane Center, West China Hospital of Sichuan University and John Wiley & Sons Australia, Ltd.

Space station data system analysis/architecture study. Task 3: Trade studies, DR-5, volume 1

NASA Technical Reports Server (NTRS)

1985-01-01

The primary objective of Task 3 is to provide additional analysis and insight necessary to support key design/programmatic decision for options quantification and selection for system definition. This includes: (1) the identification of key trade study topics; (2) the definition of a trade study procedure for each topic (issues to be resolved, key inputs, criteria/weighting, methodology); (3) conduct tradeoff and sensitivity analysis; and (4) the review/verification of results within the context of evolving system design and definition. The trade study topics addressed in this volume include space autonomy and function automation, software transportability, system network topology, communications standardization, onboard local area networking, distributed operating system, software configuration management, and the software development environment facility.

The future of Jungian analysis: strengths, weaknesses, opportunities, threats ('SWOT').

PubMed

Samuels, Andrew

2017-11-01

Using a methodology derived from management and organizational studies, the author reviews the future of Jungian analysis. The methodology is termed SWOT - strengths, weaknesses, opportunities, threats. A selected list in each of these categories is presented. The author is transparent in allowing for the fact that the paper not only derives from a public lecture on the topic, but also retains the immediacy and the contrarian and opinionated style of such a lecture. © 2017, The Society of Analytical Psychology.

78 FR 23261 - Solicitation for Nominations for Members of the U.S. Preventive Services Task Force (USPSTF)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-18

... during conference calls and via email discussions. Member duties include prioritizing topics, designing... their expertise in methodological issues such as meta-analysis, analytic modeling or clinical...

Proceedings of the tenth annual DOE low-level waste management conference: Session 2: Site performance assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-12-01

This document contains twelve papers on various aspects of low-level radioactive waste management. Topics of this volume include: performance assessment methodology; remedial action alternatives; site selection and site characterization procedures; intruder scenarios; sensitivity analysis procedures; mathematical models for mixed waste environmental transport; and risk assessment methodology. Individual papers were processed separately for the database. (TEM)

Interrogating discourse: the application of Foucault's methodological discussion to specific inquiry.

PubMed

Fadyl, Joanna K; Nicholls, David A; McPherson, Kathryn M

2013-09-01

Discourse analysis following the work of Michel Foucault has become a valuable methodology in the critical analysis of a broad range of topics relating to health. However, it can be a daunting task, in that there seems to be both a huge number of possible approaches to carrying out this type of project, and an abundance of different, often conflicting, opinions about what counts as 'Foucauldian'. This article takes the position that methodological design should be informed by ongoing discussion and applied as appropriate to a particular area of inquiry. The discussion given offers an interpretation and application of Foucault's methodological principles, integrating a reading of Foucault with applications of his work by other authors, showing how this is then applied to interrogate the practice of vocational rehabilitation. It is intended as a contribution to methodological discussion in this area, offering an interpretation of various methodological elements described by Foucault, alongside specific application of these aspects.

Advanced GIS Exercise: Predicting Rainfall Erosivity Index Using Regression Analysis

ERIC Educational Resources Information Center

Post, Christopher J.; Goddard, Megan A.; Mikhailova, Elena A.; Hall, Steven T.

2006-01-01

Graduate students from a variety of agricultural and natural resource fields are incorporating geographic information systems (GIS) analysis into their graduate research, creating a need for teaching methodologies that help students understand advanced GIS topics for use in their own research. Graduate-level GIS exercises help students understand…

Finding user personal interests by tweet-mining using advanced machine learning algorithm in R

NASA Astrophysics Data System (ADS)

Krithika, L. B.; Roy, P.; Asha Jerlin, M.

2017-11-01

The social-media plays a key role in every individual’s life by anyone’s personal views about their liking-ness/disliking-ness. This methodology is a sharp departure from the traditional techniques of inferring interests of a user from the tweets that he/she posts or receives. It is showed that the topics of interest inferred by the proposed methodology are far superior than the topics extracted by state-of-the-art techniques such as using topic models (Labelled LDA) on tweets. Based upon the proposed methodology, a system has been built, “Who is interested in what”, which can infer the interests of millions of Twitter users. A novel mechanism is proposed to infer topics of interest of individual users in the twitter social network. It has been observed that in twitter, a user generally follows experts on various topics of his/her interest in order to acquire information on those topics. A methodology based on social annotations is used to first deduce the topical expertise of popular twitter users and then transitively infer the interests of the users who follow them.

Code Pulse: Software Assurance (SWA) Visual Analytics for Dynamic Analysis of Code

DTIC Science & Technology

2014-09-01

31 4.5.1 Market Analysis...competitive market analysis to assess the tool potential. The final transition targets were selected and expressed along with our research on the topic...public release milestones. Details of our testing methodology is in our Software Test Plan deliv- erable, CP- STP -0001. A summary of this approach is

Towards a Pattern-Driven Topical Ontology Modeling Methodology in Elderly Care Homes

NASA Astrophysics Data System (ADS)

Tang, Yan; de Baer, Peter; Zhao, Gang; Meersman, Robert; Pudkey, Kevin

This paper presents a pattern-driven ontology modeling methodology, which is used to create topical ontologies in the human resource management (HRM) domain. An ontology topic is used to group concepts from different contexts (or even from different domain ontologies). We use the Organization for Economic Co-operation and Development (OECD) and the National Vocational Qualification (NVQ) as the resource to create the topical ontologies in this paper. The methodology is implemented in a tool called PAD-ON suit. The paper approach is illustrated with a use case from elderly care homes in UK.

Promoting psychology to students: embracing the multiplicity of research foci and method

PubMed Central

Rees, Clare S.

2013-01-01

In order for the discipline of psychology to continue to thrive it is imperative that future students are effectively recruited into the field. Research is an important part of the discipline and it is argued that the nature of psychological research is naturally one of multiplicity in topic and methodology and that promoting and highlighting this should be considered as a potentially effective recruitment strategy. In this study, a snap-shot of current research topics and methodologies was collected based on published papers from one typical academic psychology department in Australia. Fifty articles published in the period 2010–2013 were randomly selected and then grouped using content analysis to form topic clusters. Five main clusters were identified and included: Grief and Loss; Psychopathology; Sociocultural Studies; Attachment and Parenting; and Developmental Disorders. The studies spanned the full spectrum of research methodologies from quantitative to qualitative and had implications for assessment practices, diagnosis, prevention and treatment, education, and policy. The findings are discussed in terms of the unique characteristics of psychology as a discipline and how this diversity ought to be utilized as the main selling point of the discipline to future students. PMID:24155737

Teacher's Corner: Examining Identification Issues in Factor Analysis

ERIC Educational Resources Information Center

Hayashi, Kentaro; Marcoulides, George A.

2006-01-01

One hundred years have passed since the birth of factor analysis, during which time there have been some major developments and extensions to the methodology. Unfortunately, one issue where the widespread accumulation of knowledge has been rather slow concerns identification. This article provides a didactic discussion of the topic in an attempt…

A Comparative Analysis of Method Books for Class Jazz Instruction

ERIC Educational Resources Information Center

Watson, Kevin E.

2017-01-01

The purpose of this study was to analyze and compare instructional topics and teaching approaches included in selected class method books for jazz pedagogy through content analysis methodology. Frequency counts for the number of pages devoted to each defined instructional content category were compiled and percentages of pages allotted to each…

Resistances to Scientific Knowledge Production of Comparative Measurements of Dropout and Completion in European Higher Education

ERIC Educational Resources Information Center

Carlhed, Carina

2017-01-01

The article is a critical sociological analysis of current transnational practices on creating comparable measurements of dropout and completion in higher education and the consequences for the conditions of scientific knowledge production on the topic. The analysis revolves around questions of epistemological, methodological and symbolic types…

How to Conduct a Good Meta-Analysis in Gifted Education

ERIC Educational Resources Information Center

Steenbergen-Hu, Saiying; Olszewski-Kubilius, Paula

2016-01-01

This methodological brief introduces basic procedures and issues for conducting a high-quality meta-analysis in gifted education. Specifically, we discuss issues such as how to select a topic and formulate research problems, search for and identify qualified studies, code studies and extract data, choose and calculate effect sizes, analyze data,…

Orbiter lessons learned: A guide to future vehicle development

NASA Technical Reports Server (NTRS)

Greenberg, Harry Stan

1993-01-01

Topics addressed are: (1) wind persistence loads methodology; (2) emphasize supportability in design of reusable vehicles; (3) design for robustness; (4) improved aerodynamic environment prediction methods for complex vehicles; (5) automated integration of aerothermal, manufacturing, and structures analysis; (6) continued electronic documentation of structural design and analysis; and (7) landing gear rollout load simulations.

Metrics for Systems Thinking in the Human Dimension

DTIC Science & Technology

2016-11-01

corpora of documents. 2 Methodology Overview We present a human-in-the- loop methodology that assists researchers and analysts by characterizing...supervised learning methods. Building on this foundation, we present an unsupervised, human-in-the- loop methodology that utilizes topic models to...the definition of strong systems thinking and in the interpretation of topics, but this is what makes the human-in-the- loop methodology so effective

Developing comparative criminology and the case of China: an introduction.

PubMed

Liu, Jianhong

2007-02-01

Although comparative criminology has made significant development during the past decade or so, systematic empirical research has only developed along a few topics. Comparative criminology has never occupied a central position in criminology. This article analyzes the major theoretical and methodological impediments in the development of comparative criminology. It stresses a need to shift methodology from a conventional primary approach that uses the nation as the unit of analysis to an in-depth case study method as a primary methodological approach. The article maintains that case study method can overcome the limitation of its descriptive tradition and become a promising methodological approach for comparative criminology.

Canadian-led capacity-building in biostatistics and methodology in cardiovascular and diabetes trials: the CANNeCTIN Biostatistics and Methodological Innovation Working Group

PubMed Central

2011-01-01

The Biostatistics and Methodological Innovation Working (BMIW) Group is one of several working groups within the CANadian Network and Centre for Trials INternationally (CANNeCTIN). This programme received funding from the Canadian Institutes of Health Research and the Canada Foundation for Innovation beginning in 2008, to enhance the infrastructure and build capacity for large Canadian-led clinical trials in cardiovascular diseases (CVD) and diabetes mellitus (DM). The overall aims of the BMIW Group's programme within CANNeCTIN, are to advance biostatistical and methodological research, and to build biostatistical capacity in CVD and DM. Our program of research and training includes: monthly videoconferences on topical biostatistical and methodological issues in CVD/DM clinical studies; providing presentations on methods issues at the annual CANNeCTIN meetings; collaborating with clinician investigators on their studies; training young statisticians in biostatistics and methods in CVD/DM trials and organizing annual symposiums on topical methodological issues. We are focused on the development of new biostatistical methods and the recruitment and training of highly qualified personnel - who will become leaders in the design and analysis of CVD/DM trials. The ultimate goal is to enhance global health by contributing to efforts to reduce the burden of CVD and DM. PMID:21332987

Satellite services system analysis study. Volume 2: Satellite and services user model

NASA Technical Reports Server (NTRS)

1981-01-01

Satellite services needs are analyzed. Topics include methodology: a satellite user model; representative servicing scenarios; potential service needs; manned, remote, and automated involvement; and inactive satellites/debris. Satellite and services user model development is considered. Groundrules and assumptions, servicing, events, and sensitivity analysis are included. Selection of references satellites is also discussed.

On Constructing, Grouping and Using Topical Ontology for Semantic Matching

NASA Astrophysics Data System (ADS)

Tang, Yan; de Baer, Peter; Zhao, Gang; Meersman, Robert

An ontology topic is used to group concepts from different contexts (or even from different domain ontologies). This paper presents a pattern-driven modeling methodology for constructing and grouping topics in an ontology (PAD-ON methodology), which is used for matching similarities between competences in the human resource management (HRM) domain. The methodology is supported by a tool called PAD-ON. This paper demonstrates our recent achievement in the work from the EC Prolix project. The paper approach is applied to the training processes at British Telecom as the test bed.

Russian Influence on NATO Member/Non-Member Relationships: A Case Study of the US-Ukraine Military to Military Relationship

DTIC Science & Technology

2002-12-01

influence? C. METHODOLOGY The methodology for this thesis will be a qualitative analysis of topical scholarly texts, government policy, personal ...other elements of collective security. The best example of collective defense language is contained in Article 5 of the Washington Treaty which... histrionics , has been essentially powerless to halt the enlargement of NATO. All of the actions taken by Russia during the Kosovo crisis in 1999

Social Media Participation in Urban Planning: a New way to Interact and Take Decisions

NASA Astrophysics Data System (ADS)

López-Ornelas, E.; Abascal-Mena, R.; Zepeda-Hernández, S.

2017-09-01

Social Media Participation can be very important when you have to make an important decision about a topic related to urban planning. Textual analysis to identify the sentiment about a topic or, community detection and user analysis to identify the actors involved on a discussion can be very important for the persons or institutions that have to take an important decision. In this paper we propose a methodological design to analyse participation in social media. We study the installation of a new airport in Mexico City as a case of study to highlight the importance of conducting a study of this nature.

An Analysis of a Decade of Research in 10 Instructional Design and Technology Journals

ERIC Educational Resources Information Center

West, Richard Edward; Borup, Jered

2014-01-01

In this paper, we review findings from an analysis of the past decade (2001-10) of research in 10 major journals in the field of instructional design and technology. Each research paper published in these journals during this decade was categorized according to its focus or methodology, topical keywords, authorship and citation trends; and the…

Working with Data: Discovering Knowledge through Mining and Analysis; Systematic Knowledge Management and Knowledge Discovery; Text Mining; Methodological Approach in Discovering User Search Patterns through Web Log Analysis; Knowledge Discovery in Databases Using Formal Concept Analysis; Knowledge Discovery with a Little Perspective.

ERIC Educational Resources Information Center

Qin, Jian; Jurisica, Igor; Liddy, Elizabeth D.; Jansen, Bernard J; Spink, Amanda; Priss, Uta; Norton, Melanie J.

2000-01-01

These six articles discuss knowledge discovery in databases (KDD). Topics include data mining; knowledge management systems; applications of knowledge discovery; text and Web mining; text mining and information retrieval; user search patterns through Web log analysis; concept analysis; data collection; and data structure inconsistency. (LRW)

Access and Ownership in the Academic Environment: One Library's Progress Report.

ERIC Educational Resources Information Center

Brin, Beth; Cochran, Elissa

1994-01-01

Describes the methodology used at the University of Arizona Library to address the issue of access versus ownership of library materials. Topics discussed include participatory management; data collection, including focus groups, interlibrary loan statistics, and graduate research citation analysis; and resulting recommendations, including…

Occupant Protection Project

NASA Technical Reports Server (NTRS)

Bopp, Genie; Somers, Jeff; Granderson, Brad; Gernhardt, Mike; Currie, Nancy; Lawrence, Chuck

2010-01-01

Topics include occupant protection overview with a focus on crew protection during dynamic phases of flight; occupant protection collaboration; modeling occupant protection; occupant protection considerations; project approach encompassing analysis tools, injury criteria, and testing program development; injury criteria update methodology, unique effects of pressure suits and other factors; and a summary.

Managing Awkward, Sensitive, or Delicate Topics in (Chinese) Radio Medical Consultations

ERIC Educational Resources Information Center

Yu, Guodong; Wu, Yaxin

2015-01-01

This study, using conversation analysis as the research methodology, probes into the use of "nage" (literally "that") as a practice of managing awkward, sensitive, or delicate issues in radio phone-in medical consultations about sex-related problems. Through sequential manipulation and turn manipulation, the caller uses…

Single-Subject Research in Gifted Education

ERIC Educational Resources Information Center

Simonsen, Brandi; Little, Catherine A.

2011-01-01

Single-subject research (SSR) is an experimental research tradition that is well established in other fields (e.g., special education, behavior analysis) but has rarely been applied to topics in gifted education. In this Methodological Brief, Brandi Simonsen and Catherine A. Little from the University of Connecticut highlight the key features of…

In Vitro Evaluation of a Program for Machine-Aided Indexing.

ERIC Educational Resources Information Center

Jacquemin, Christian; Daille, Beatrice; Royaute, Jean; Polanco, Xavier

2002-01-01

Presents the human evaluation of ILIAD, a program for machine-aided indexing that was designed to assist expert librarians in computer-aided indexing and document analysis. Topics include controlled indexing and free indexing; natural language and concept-based information retrieval; evaluation methodology; syntactic variations; and a comparison…

Planning a dynamic kill

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abel, L.W.

1996-05-01

This article discusses the methodology, design philosophy, and guidelines for planning a dynamic-kill operation for a wild well. The topics covered are two methods of computer analysis for designing dynamic-kill requirements, the design process, determining the pumping spread, and the pitfalls that a designer faces in planning a dynamic kill.

Manual for the Comparative Politics Laboratory: Conditions for Effective Democracy.

ERIC Educational Resources Information Center

Fogelman, Edwin; Zingale, Nancy

This manual introduces undergraduate students in political science to major types of data and methods for cross-national quantitative analysis. The manual's topic, Conditions for Effective Democracy, was chosen because it incorporates several different kinds of data and illustrates various methodological problems. The data are cross-sectional…

High School Students Presenting Science: An Interactional Sociolinguistic Analysis.

ERIC Educational Resources Information Center

Bleicher, Robert

1994-01-01

This study examines strategies employed by students as they make science presentations; assesses student's conceptual understandings of particular science topics; and investigates gender differences. Focuses on the methodology employed and how it helps inform these goals. Advice for teaching students to present science, implications for use of…

From "Sooo excited!!!" to "So proud": using language to study development.

PubMed

Kern, Margaret L; Eichstaedt, Johannes C; Schwartz, H Andrew; Park, Gregory; Ungar, Lyle H; Stillwell, David J; Kosinski, Michal; Dziurzynski, Lukasz; Seligman, Martin E P

2014-01-01

We introduce a new method, differential language analysis (DLA), for studying human development in which computational linguistics are used to analyze the big data available through online social media in light of psychological theory. Our open vocabulary DLA approach finds words, phrases, and topics that distinguish groups of people based on 1 or more characteristics. Using a data set of over 70,000 Facebook users, we identify how word and topic use vary as a function of age and compile cohort specific words and phrases into visual summaries that are face valid and intuitively meaningful. We demonstrate how this methodology can be used to test developmental hypotheses, using the aging positivity effect (Carstensen & Mikels, 2005) as an example. While in this study we focused primarily on common trends across age-related cohorts, the same methodology can be used to explore heterogeneity within developmental stages or to explore other characteristics that differentiate groups of people. Our comprehensive list of words and topics is available on our web site for deeper exploration by the research community. PsycINFO Database Record (c) 2014 APA, all rights reserved.

Topic-Focused Analysis of Verbal Interaction in a Case of Integrative Therapy with a Young Woman Presenting with Symptoms of Depression

ERIC Educational Resources Information Center

Reichelt, Sissel; Skjerve, Jan; McLeod, John

2017-01-01

It is increasingly recognised that single-case analysis makes a valuable contribution to the evidence base for psychotherapy, alongside other methodologies. Such analyses make it possible to investigate the unfolding process of change in therapy, and develop an understanding of change factors that contribute to outcome. One of the key challenges…

A Critical Appraisal of the 1998 Meta-Analytic Review of Child Sexual Abuse Outcomes Reported by Rind, Tromovitch, and Bauserman.

ERIC Educational Resources Information Center

Whittenburg, John A.; Tice, Pamela Paradis; Baker, Gail L.; Lemmey, Dorothy E.

2001-01-01

Presents a methodological critique of the 1998 meta-analysis of child sexual abuse outcomes by Rind et al. By restricting a supposedly broad meta-analysis to only some of the population in question, the conclusions they drew regarding this complex topic, primarily that adult-child sex is not necessarily harmful, are invalid. (Contains 33…

The Use of OPAC in a Large Academic Library: A Transactional Log Analysis Study of Subject Searching

ERIC Educational Resources Information Center

Villen-Rueda, Luis; Senso, Jose A.; de Moya-Anegon, Felix

2007-01-01

The analysis of user searches in catalogs has been the topic of research for over four decades, involving numerous studies and diverse methodologies. The present study looks at how different types of users effect queries in the catalog of a university library. For this purpose, we analyzed log files to determine which was the most frequent type of…

Trends analysis on research articles in the korean journal of medical education.

PubMed

Lee, Young Hee; Lee, Young-Mee; Kwon, Hyojin

2012-12-01

The purpose of this study was to examine the chronological changes and progress in medical education research in Korea and to identify the less investigated topics that need further study and improvement with regard to methodological quality. Of the 590 articles that were published from 1989 to 2010 in the Korean Journal of Medical Education, 386 original research papers were extracted for the analysis. The extracted papers were systematically reviewed using 2 analysis schemes that we developed: one scheme was designed to classify research topics, and the other determined the methodology that was used. The main results were as follows: The most popular research areas were curriculum, educational method, and evaluation in basic medical education; in contrast, studies that addressed postgraduate education, continuous professional development, and educational administration were less frequent; The most frequently studied topics were clinical performance/skills evaluation, clerkship, curriculum development, and problem-based learning, Quantitative studies predominated over qualitative studies and mixed methods (265 vs. 95 vs. 26). Two hundred forty papers were descriptive, cross-sectional studies, and 17 were experimental studies. Most qualitative studies were non-participation observational studies. In conclusion, there has been dramatic growth in the extent of medical education research in Korea in the past two decades. However, more studies that investigate the graduate medical education and the continuous professional development should be performed. Moreover, robust experimental designs and methods should be applied to provide stronger evidence that can practice best-evidence medical education.

Combining formal and functional approaches to topic structure.

PubMed

Zellers, Margaret; Post, Brechtje

2012-03-01

Fragmentation between formal and functional approaches to prosodic variation is an ongoing problem in linguistic research. In particular, the frameworks of the Phonetics of Talk-in-Interaction (PTI) and Empirical Phonology (EP) take very different theoretical and methodological approaches to this kind of variation. We argue that it is fruitful to adopt the insights of both PTI's qualitative analysis and EP's quantitative analysis and combine them into a multiple-methods approach. One realm in which it is possible to combine these frameworks is in the analysis of discourse topic structure and the prosodic cues relevant to it. By combining a quantitative and a qualitative approach to discourse topic structure, it is possible to give a better account of the observed variation in prosody, for example in the case of fundamental frequency (F0) peak timing, which can be explained in terms of pitch accent distribution over different topic structure categories. Similarly, local and global patterns in speech rate variation can be better explained and motivated by adopting insights from both PTI and EP in the study of topic structure. Combining PTI and EP can provide better accounts of speech data as well as opening up new avenues of investigation which would not have been possible in either approach alone.

Gis-Based Accessibility Analysis of Urban Emergency Shelters: the Case of Adana City

NASA Astrophysics Data System (ADS)

Unal, M.; Uslu, C.

2016-10-01

Accessibility analysis of urban emergency shelters can help support urban disaster prevention planning. Pre-disaster emergency evacuation zoning has become a significant topic on disaster prevention and mitigation research. In this study, we assessed the level of serviceability of urban emergency shelters within maximum capacity, usability, sufficiency and a certain walking time limit by employing spatial analysis techniques of GIS-Network Analyst. The methodology included the following aspects: the distribution analysis of emergency evacuation demands, the calculation of shelter space accessibility and the optimization of evacuation destinations. This methodology was applied to Adana, a city in Turkey, which is located within the Alpine-Himalayan orogenic system, the second major earthquake belt after the Pacific-Belt. It was found that the proposed methodology could be useful in aiding to understand the spatial distribution of urban emergency shelters more accurately and establish effective future urban disaster prevention planning. Additionally, this research provided a feasible way for supporting emergency management in terms of shelter construction, pre-disaster evacuation drills and rescue operations.

Development of computer-assisted instruction application for statistical data analysis android platform as learning resource

NASA Astrophysics Data System (ADS)

Hendikawati, P.; Arifudin, R.; Zahid, M. Z.

2018-03-01

This study aims to design an android Statistics Data Analysis application that can be accessed through mobile devices to making it easier for users to access. The Statistics Data Analysis application includes various topics of basic statistical along with a parametric statistics data analysis application. The output of this application system is parametric statistics data analysis that can be used for students, lecturers, and users who need the results of statistical calculations quickly and easily understood. Android application development is created using Java programming language. The server programming language uses PHP with the Code Igniter framework, and the database used MySQL. The system development methodology used is the Waterfall methodology with the stages of analysis, design, coding, testing, and implementation and system maintenance. This statistical data analysis application is expected to support statistical lecturing activities and make students easier to understand the statistical analysis of mobile devices.

Carbon Fiber Risk Analysis. [conference

NASA Technical Reports Server (NTRS)

1979-01-01

The scope and status of the effort to assess the risks associated with the accidental release of carbon/graphite fibers from civil aircraft is presented. Vulnerability of electrical and electronic equipment to carbon fibers, dispersal of carbon fibers, effectiveness of filtering systems, impact of fiber induced failures, and risk methodology are among the topics covered.

Research in the Field of Inclusive Education: Time for a Rethink?

ERIC Educational Resources Information Center

Messiou, Kyriaki

2017-01-01

This paper sets out to challenge thinking and practice amongst researchers in the field of inclusive education. It does this based on an analysis of published articles in the "International Journal of Inclusive Education" between 2005 and 2015, which identified topics and methodologies used in studies of inclusive education. The analysis…

An Instrument for Analyzing Arguments Produced in Modeling-Based Chemistry Lessons

ERIC Educational Resources Information Center

Mendonça, Paula Cristina Cardoso; Justi, Rosária

2014-01-01

Previous research on argumentation in science education has focused on the understanding of relationships between modeling and argumentation (an important topic that only recently has been addressed in few empirical studies), and the methodological difficulties related to the analysis of arguments produced in classrooms. Our study is related to…

Ohio Geographers: Recent Research Themes. Volume Number 1: 1973.

ERIC Educational Resources Information Center

Pyle, Gerald F., Ed.

Eight professional geography research papers presented at the Geography Section of the 1973 annual meeting of the Ohio Academy of Science are provided. The specific topics of concern range from methodological essays to the quantitative analysis of historical geographic information. The titles of the papers are (1) An Attempt at Reform in Regional…

The history of behavior analysis: Some historiography and a bibliography

PubMed Central

Morris, Edward K.; Todd, James T.; Midgley, Bryan D.; Schneider, Susan M.; Johnson, Lisa M.

1990-01-01

This article has two main purposes. First, it introduces the discipline of historiography and, second, it provides a selected bibliography on the history of behavior analysis. In introducing the former in the context of the latter, four important methodological considerations involved in the process and product of historiography are described: The sources from which historical materials are drawn (i.e., primary, secondary, and tertiary) and three dimensions along which historiography is conducted and evaluated—internalist vs. externalist, great person vs. Zeitgeist, and presentist vs. historicist. Integrated throughout are four purposes for the historiography of behavior analysis, as well as an overview of the topics covered in the extant literature. The manuscript concludes with a listing of current bibliographic material by publication type and topic. PMID:22478061

Fatigue methodology III; Proceedings of the AHS National Technical Specialists' Meeting on Advanced Rotorcraft Structures, Scottsdale, AZ, Oct. 3-5, 1989

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1989-01-01

Papers on rotorcraft and fatigue methodology are presented, covering topics such as reliability design for rotorcraft, a comparison between theory and fatigue test data on stress concentration factors, the retirement lives of rolling element bearings, hydrogen embrittlement risk analysis for high hardness steel parts, and rotating system load monitoring with minimum fixed system instrumentation. Additional topics include usage data collection to improve structural integrity of operational helicopters, usage monitory of military helicopters, improvements to the fatigue substantiation of the H-60 composite tail rotor blade, helicopter surviellance programs, and potential application of automotive fatigue technology in rotorcraft design. Also, consideration ismore » given to fatigue evaluation of C/MH-53 E main rotor damper threaded joints, SH-2F airframe fatigue test program, a ply termination concept for improving fracture and fatigue strength of composite laminates, the analysis and testing of composite panels subject to muzzle blast effects, the certification plan for an all-composite main rotor flexbeam, and the effects of stacking sequence on the flexural strength of composite beams.« less

Cytochemical studies of planetary microorganisms - Explorations in exobiology

NASA Technical Reports Server (NTRS)

Lederberg, J.

1972-01-01

Analytical methodology using gas chromatography and mass spectrography for improved physiological monitoring of astronauts is developed. Reported research covers the following topics: (1) Chlorination of DNA bases; (2) mass fragmentography; (3) mass spectrometry; (4) urine analysis for metabolic constituents; (5) analysis of natural products by mass spectrometry; (6) computer identification of unknown molecular compounds; (7) fluorescent sorter for cell separation; (8) Mariner Mars 1971 orbital photography; and (9) Viking Lander imagery.

Network Data: Statistical Theory and New Models

DTIC Science & Technology

2016-02-17

SECURITY CLASSIFICATION OF: During this period of review, Bin Yu worked on many thrusts of high-dimensional statistical theory and methodologies. Her...research covered a wide range of topics in statistics including analysis and methods for spectral clustering for sparse and structured networks...2,7,8,21], sparse modeling (e.g. Lasso) [4,10,11,17,18,19], statistical guarantees for the EM algorithm [3], statistical analysis of algorithm leveraging

Teaching of Computer Science Topics Using Meta-Programming-Based GLOs and LEGO Robots

ERIC Educational Resources Information Center

Štuikys, Vytautas; Burbaite, Renata; Damaševicius, Robertas

2013-01-01

The paper's contribution is a methodology that integrates two educational technologies (GLO and LEGO robot) to teach Computer Science (CS) topics at the school level. We present the methodology as a framework of 5 components (pedagogical activities, technology driven processes, tools, knowledge transfer actors, and pedagogical outcomes) and…

Key topics in surgical research and methodology Thanos Athanasiou Key topics in surgical research and methodology , Haile Debas and Ara Darzi Springer Pages: 1090 £180 9783540719144 3540719148 [Formula: see text].

PubMed

2011-01-21

If the editors' intention was to produce a comprehensive text book that will be of value to healthcare professionals interested in surgical research and improvements in health care, they have succeeded.

Analysis of individual risk belief structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tonn, B.E.; Travis, C.B.; Arrowood, L.

An interactive computer program developed at Oak Ridge National Laboratory is presented as a methodology to model individualized belief structures. The logic and general strategy of the model is presented for two risk topics: AIDs and toxic waste. Subjects identified desirable and undesirable consequences for each topic and formulated an associative rule linking topic and consequence in either a causal or correlational framework. Likelihood estimates, generated by subjects in several formats (probability, odds statements, etc.), constituted one outcome measure. Additionally, source of belief (personal experience, news media, etc.) and perceived personal and societal impact are reviewed. Briefly, subjects believe thatmore » AIDs causes significant emotional problems, and to a lesser degree, physical health problems whereas toxic waste causes significant environmental problems.« less

77 FR 39521 - Applications and Amendments to Facility Operating Licenses and Combined Licenses Involving...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-03

... Methodology for Boiling Water Reactors, June 2011. To support use of Topical Report ANP-10307PA, Revision 0... the NRC's E-Filing system does not support unlisted software, and the NRC Meta System Help Desk will... Water Reactors with AREVA Topical Report ANP- 10307PA, Revision 0, ``AREVA MCPR Safety Limit Methodology...

The Use of Poetry in a Spiral-Patterned Methodology for Research about Love in Early Childhood

ERIC Educational Resources Information Center

Cousins, Sarah

2017-01-01

Research about love in early childhood education and care is rare. Love is difficult topic to research and write about in scholarly contexts. In order to properly explore love in professional contexts, practitioner narratives on the topic were sought through individual, unstructured interviews. A spiral-patterned methodological approach was…

Quantitative Analysis of Uncertainty in Medical Reporting: Creating a Standardized and Objective Methodology.

PubMed

Reiner, Bruce I

2018-04-01

Uncertainty in text-based medical reports has long been recognized as problematic, frequently resulting in misunderstanding and miscommunication. One strategy for addressing the negative clinical ramifications of report uncertainty would be the creation of a standardized methodology for characterizing and quantifying uncertainty language, which could provide both the report author and reader with context related to the perceived level of diagnostic confidence and accuracy. A number of computerized strategies could be employed in the creation of this analysis including string search, natural language processing and understanding, histogram analysis, topic modeling, and machine learning. The derived uncertainty data offers the potential to objectively analyze report uncertainty in real time and correlate with outcomes analysis for the purpose of context and user-specific decision support at the point of care, where intervention would have the greatest clinical impact.

"Women Made It a Home": Representations of Women in Social Studies

ERIC Educational Resources Information Center

Schmeichel, Mardi

2014-01-01

This article explores recently published P-12 social studies lesson plans that include women to examine how attending to women is "getting done" in the field and how the lessons represent women and women's experiences. Using discourse analysis methodologies, the author demonstrates that women have been included as topics in ways that do…

Emotional Issues and Peer Relations in Gifted Elementary Students: Regression Analysis of National Data

ERIC Educational Resources Information Center

Wiley, Kristofor R.

2013-01-01

Many of the social and emotional needs that have historically been associated with gifted students have been questioned on the basis of recent empirical evidence. Research on the topic, however, is often limited by sample size, selection bias, or definition. This study addressed these limitations by applying linear regression methodology to data…

Effects of Reinforcement Schedule on Facilitation of Operant Extinction by Chlordiazepoxide

ERIC Educational Resources Information Center

Leslie, Julian C.; Shaw, David; Gregg, Gillian; McCormick, Nichola; Reynolds, David S.; Dawson, Gerard R.

2005-01-01

Learning and memory are central topics in behavioral neuroscience, and inbred mice strains are widely investigated. However, operant conditioning techniques are not as extensively used in this field as they should be, given the effectiveness of the methodology of the experimental analysis of behavior. In the present study, male C57Bl/6 mice,…

Key concepts and methods in social vulnerability and adaptive capacity

Treesearch

Daniel J. Murphy; Carina Wyborn; Laurie Yung; Daniel R. Williams

2015-01-01

National forests have been asked to assess how climate change will impact nearby human communities. To assist their thinking on this topic, we examine the concepts of social vulnerability and adaptive capacity with an emphasis on a range of theoretical and methodological approaches. This analysis is designed to help researchers and decision-makers select appropriate...

Web-Based OPACs in Indian Academic Libraries: A Functional Comparison

ERIC Educational Resources Information Center

Kapoor, Kanta; Goyal, O. P.

2007-01-01

Purpose: The paper seeks to provide a comparative analysis of the functionality of five web-based OPACs available in Indian academic libraries. Design/methodology/approach: Same-topic searches were carried out by three researchers on the web-based OPACs of Libsys, VTLS's iPortal, NewGenLib, Troodon, and Alice for Windows, implemented in five…

Recent advances in combination of capillary electrophoresis with mass spectrometry: methodology and theory.

PubMed

Klepárník, Karel

2015-01-01

This review focuses on the latest development of microseparation electromigration methods in capillaries and microfluidic devices with MS detection and identification. A wide selection of 183 relevant articles covers the literature published from June 2012 till May 2014 as a continuation of the review article on the same topic by Kleparnik [Electrophoresis 2013, 34, 70-86]. Special attention is paid to the new improvements in the theory of instrumentation and methodology of MS interfacing with capillary versions of zone electrophoresis, ITP, and IEF. Ionization methods in MS include ESI, MALDI, and ICP. Although the main attention is paid to the development of instrumentation and methodology, representative examples illustrate also applications in the proteomics, glycomics, metabolomics, biomarker research, forensics, pharmacology, food analysis, and single-cell analysis. The combinations of MS with capillary versions of electrochromatography and micellar electrokinetic chromatography are not included. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Introduction to a special issue on concept mapping.

PubMed

Trochim, William M; McLinden, Daniel

2017-02-01

Concept mapping was developed in the 1980s as a unique integration of qualitative (group process, brainstorming, unstructured sorting, interpretation) and quantitative (multidimensional scaling, hierarchical cluster analysis) methods designed to enable a group of people to articulate and depict graphically a coherent conceptual framework or model of any topic or issue of interest. This introduction provides the basic definition and description of the methodology for the newcomer and describes the steps typically followed in its most standard canonical form (preparation, generation, structuring, representation, interpretation and utilization). It also introduces this special issue which reviews the history of the methodology, describes its use in a variety of contexts, shows the latest ways it can be integrated with other methodologies, considers methodological advances and developments, and sketches a vision of the future of the method's evolution. Copyright © 2016 Elsevier Ltd. All rights reserved.

[The grounded theory as a methodological alternative for nursing research].

PubMed

dos Santos, Sérgio Ribeiro; da Nóbrega, Maria Miriam

2002-01-01

This study presents a method of interpretative and systematic research with appliance to the development of studies in nursing called "the grounded theory", whose theoretical support is the symbolic interactionism. The purpose of the paper is to describe the grounded theory as an alternative methodology for the construction of knowledge in nursing. The study highlights four topics: the basic principle, the basic concepts, the trajectory of the method and the process of analysis of the data. We conclude that the systematization of data and its interpretation, based on social actors' experience, constitute strong subsidies to generate theories through this research tool.

75 FR 8649 - Request for Comments on Methodology for Conducting an Independent Study of the Burden of Patent...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-25

...] Request for Comments on Methodology for Conducting an Independent Study of the Burden of Patent-Related... methodologies for performing such a study (Methodology Report). ICF has now provided the USPTO with its Methodology Report, in which ICF recommends methodologies for addressing various topics about estimating the...

A Systematic Method for Reviewing and Analyzing Health Information on Consumer-Oriented Websites.

PubMed

Rew, Lynn; Saenz, Ashley; Walker, Lorraine O

2018-05-29

A discussion of a proposed method for analyzing the quality of consumer-oriented websites that provide health-related information. The quality of health information available to consumers online varies widely in quality. In an effort to improve the quality of online information, experts have undertaken systematic reviews on selected health topics; however, no standardized comprehensive methodology currently exists for such review. An eight-step method is recommended embracing the following steps: (1) select topic; (2) determine the purpose of the analysis; (3) select search terms and engines; (4) develop and apply website inclusion and exclusion criteria; (5) develop processes and tools to manage search results; (6) specify measures of quality; (7) compute readability; (8) evaluate websites. Each of these steps is illustrated in relation to the health topic of gynecomastia, a physical and mental health challenge for many adolescent males and young men. Although most extant analyses of consumer-oriented websites have focused on disease conditions and their treatment, website-analysis methodology would encourage analyses that fall into the nursing care domain. The method outlined in this paper is intended to provide nurses and others who work with specific patient populations with the tools needed for website analytic studies. Such studies provide a foundation for making recommendations about quality websites, as well as identifying gaps in online information for health consumers. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Knowledge and Values in Science Textbooks Concerning Complexity in Ecological Systems and Environmental Problems: A Cross-cultural Study on Secondary School Manuals

ERIC Educational Resources Information Center

Boujemaa, Agorram; Silvia, Caravita; Adriana, Valente; Daniela, Luzi; Nicola, Margnelli

2009-01-01

The study was carried out within the European research project "Biology, Health and Environmental Education for Better Citizenship" that joined 18 European and North-African countries. We report here the methodology and some of the conclusions drawn from an analysis of science textbooks that considered the topics ecology and…

Residual Strength Characterization of Unitized Structures Fabricated Using Different Manufacturing Technologies

NASA Technical Reports Server (NTRS)

Seshadri, B. R.; Smith, S. W.; Johnston, W. M.

2008-01-01

This viewgraph presentation describes residual strength analysis of integral structures fabricated using different manufacturing procedures. The topics include: 1) Built-up and Integral Structures; 2) Development of Prediction Methodology for Integral Structures Fabricated using different Manufacturing Procedures; 3) Testing Facility; 4) Fracture Parameters Definition; 5) Crack Branching in Integral Structures; 6) Results and Discussion; and 7) Concluding Remarks.

Analysis of the Methods and Research Topics in a Sample of the Brazilian Distance Education Publications, 1992 to 2007

ERIC Educational Resources Information Center

de Oliveira Neto, Jose Dutra; dos Santos, Elaine Maria

2010-01-01

The objective of this study was to identify the methodological approaches employed in a sample of Brazilian distance education scientific literature and compare with similar publications in the United States. Brazilian sample articles (N = 983) published in several journals and meetings were compared with a sample of articles published in…

A methodological analysis of chaplaincy research: 2000-2009.

PubMed

Galek, Kathleen; Flannelly, Kevin J; Jankowski, Katherine R B; Handzo, George F

2011-01-01

The present article presents a comprehensive review and analysis of quantitative research conducted in the United States on chaplaincy and closely related topics published between 2000 and 2009. A combined search strategy identified 49 quantitative studies in 13 journals. The analysis focuses on the methodological sophistication of the studies, compared to earlier research on chaplaincy and pastoral care. Cross-sectional surveys of convenience samples still dominate the field, but sample sizes have increased somewhat over the past three decades. Reporting of the validity and reliability of measures continues to be low, although reporting of response rates has improved. Improvements in the use of inferential statistics and statistical controls were also observed, compared to previous research. The authors conclude that more experimental research is needed on chaplaincy, along with an increased use of hypothesis testing, regardless of the research designs that are used.

Mapping epidemiology's past to inform its future: metaknowledge analysis of epidemiologic topics in leading journals, 1974-2013.

PubMed

Trinquart, Ludovic; Galea, Sandro

2015-07-15

An empiric perspective on what epidemiology has studied over time might inform discussions about future directions for the discipline. We aimed to identify the main areas of epidemiologic inquiry and determine how they evolved over time in 5 high-impact epidemiologic journals. We analyzed the titles and abstracts of 20,895 articles that were published between 1974 and 2013. In 5 time periods that reflected approximately equal numbers of articles, we identified the main topics by clustering terms based on co-occurrence. Infectious disease and cardiovascular disease epidemiology were the prevailing topics over the 5 periods. Cancer epidemiology was a major topic from 1974 to 2001 but disappeared thereafter. Nutritional epidemiology gained relative importance from 1974 to 2013. Environmental epidemiology appeared during 1996-2001 and continued to be important, whereas 2 clusters related to methodology and meta-analysis in genetics appeared during 2008-2013. Several areas of epidemiology, including injury or psychiatric epidemiology, did not make an appearance as major topics at any time. In an ancillary analysis of 6 high-impact general medicine journals, we found patterns of epidemiologic articles that were overall consistent with the findings in epidemiologic journals. This metaknowledge investigation allowed identification of the dominant topics in and conversely those that were absent from 5 major epidemiologic journals. We discuss implications for the field. © The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

A quality evaluation methodology of health web-pages for non-professionals.

PubMed

Currò, Vincenzo; Buonuomo, Paola Sabrina; Onesimo, Roberta; de Rose, Paola; Vituzzi, Andrea; di Tanna, Gian Luca; D'Atri, Alessandro

2004-06-01

The proposal of an evaluation methodology for determining the quality of healthcare web sites for the dissemination of medical information to non-professionals. Three (macro) factors are considered for the quality evaluation: medical contents, accountability of the authors, and usability of the web site. Starting from two results in the literature the problem of whether or not to introduce a weighting function has been investigated. This methodology has been validated on a specialized information content, i.e., sore throats, due to the large interest such a topic enjoys with target users. The World Wide Web was accessed using a meta-search system merging several search engines. A statistical analysis was made to compare the proposed methodology with the obtained ranks of the sample web pages. The statistical analysis confirms that the variables examined (per item and sub factor) show substantially similar ranks and are capable of contributing to the evaluation of the main quality macro factors. A comparison between the aggregation functions in the proposed methodology (non-weighted averages) and the weighting functions, derived from the literature, allowed us to verify the suitability of the method. The proposed methodology suggests a simple approach which can quickly award an overall quality score for medical web sites oriented to non-professionals.

Analyzing 7000 texts on deep brain stimulation: what do they tell us?

PubMed

Ineichen, Christian; Christen, Markus

2015-01-01

The enormous increase in numbers of scientific publications in the last decades requires quantitative methods for obtaining a better understanding of topics and developments in various fields. In this exploratory study, we investigate the emergence, trends, and connections of topics within the whole text corpus of the deep brain stimulation (DBS) literature based on more than 7000 papers (title and abstracts) published between 1991 to 2014 using a network approach. Taking the co-occurrence of basic terms that represent important topics within DBS as starting point, we outline the statistics of interconnections between DBS indications, anatomical targets, positive, and negative effects, as well as methodological, technological, and economic issues. This quantitative approach confirms known trends within the literature (e.g., regarding the emergence of psychiatric indications). The data also reflect an increased discussion about complex issues such as personality connected tightly to the ethical context, as well as an apparent focus on depression as important DBS indication, where the co-occurrence of terms related to negative effects is low both for the indication as well as the related anatomical targets. We also discuss consequences of the analysis from a bioethical perspective, i.e., how such a quantitative analysis could uncover hidden subject matters that have ethical relevance. For example, we find that hardware-related issues in DBS are far more robustly connected to an ethical context compared to impulsivity, concrete side-effects or death/suicide. Our contribution also outlines the methodology of quantitative text analysis that combines statistical approaches with expert knowledge. It thus serves as an example how innovative quantitative tools can be made useful for gaining a better understanding in the field of DBS.

Analyzing 7000 texts on deep brain stimulation: what do they tell us?

PubMed Central

Ineichen, Christian; Christen, Markus

2015-01-01

The enormous increase in numbers of scientific publications in the last decades requires quantitative methods for obtaining a better understanding of topics and developments in various fields. In this exploratory study, we investigate the emergence, trends, and connections of topics within the whole text corpus of the deep brain stimulation (DBS) literature based on more than 7000 papers (title and abstracts) published between 1991 to 2014 using a network approach. Taking the co-occurrence of basic terms that represent important topics within DBS as starting point, we outline the statistics of interconnections between DBS indications, anatomical targets, positive, and negative effects, as well as methodological, technological, and economic issues. This quantitative approach confirms known trends within the literature (e.g., regarding the emergence of psychiatric indications). The data also reflect an increased discussion about complex issues such as personality connected tightly to the ethical context, as well as an apparent focus on depression as important DBS indication, where the co-occurrence of terms related to negative effects is low both for the indication as well as the related anatomical targets. We also discuss consequences of the analysis from a bioethical perspective, i.e., how such a quantitative analysis could uncover hidden subject matters that have ethical relevance. For example, we find that hardware-related issues in DBS are far more robustly connected to an ethical context compared to impulsivity, concrete side-effects or death/suicide. Our contribution also outlines the methodology of quantitative text analysis that combines statistical approaches with expert knowledge. It thus serves as an example how innovative quantitative tools can be made useful for gaining a better understanding in the field of DBS. PMID:26578908

[Noninvasive ventilation. The 2015 guidelines from the Groupe Assistance Ventilatoire (GAV) of the Société de Pneumologie de Langue Française (SPLF)].

PubMed

Rabec, C; Cuvelier, A; Cheval, C; Jaffre, S; Janssens, J-P; Mercy, M; Prigent, A; Rouault, S; Talbi, S; Vandenbroeck, S; Gonzalez-Bermejo, J

2016-12-01

A task force issued from the Groupe Assistance Ventilatoire (GAV) of the Société de Pneumologie de Langue Française (SPLF) was committed to develop a series of expert advice concerning various practical topics related to long-term non invasive ventilation by applying the Choosing Wisely ® methodology. Three topics were selected: monitoring of noninvasive ventilation, the interpretation of data obtained from built-in devices coupled to home ventilators and the role of hybrid modes (target volume with variable pressure support. For each topic, the experts have developed practical tips based on a comprehensive analysis of recent insights and evidence from the literature and from clinical experience. Copyright © 2016 SPLF. Published by Elsevier Masson SAS. All rights reserved.

SETI: A good introductory physics topic

NASA Astrophysics Data System (ADS)

Hobson, Art

1997-04-01

If America is to achieve the science literacy that is essential to industrialized democracy, all students must study such topics as scientific methodology, pseudoscience, ozone depletion, and global warming. My large-enrollment liberal-arts physics course covers the great principles of physics along with several such philosophical and societal topics. It is easy to include the interdisciplinary context of physics in courses for non-scientists, because these courses are flexible, conceptual, and taught to students whose interests span a broad range. Students find these topics relevant and fascinating, leading to large enrollments by non-scientists even in courses labeled ''physics.'' I will discuss my approach to teaching the search for extra-terrestrial intelligence (SETI), a topic with lots of good physics and with connections to scientific methodology and pseudoscience. A textbook for this kind of course has been published, Physics: Concepts and Connections (Prentice-Hall, 1995).

Methodological Issues and Practices in Qualitative Research.

ERIC Educational Resources Information Center

Bradley, Jana

1993-01-01

Discusses methodological issues concerning qualitative research and describes research practices that qualitative researchers use to address these methodological issues. Topics discussed include the researcher as interpreter, the emergent nature of qualitative research, understanding the experience of others, trustworthiness in qualitative…

Parents' Motives for Home Education: The Influence of Methodological Design and Social Context

ERIC Educational Resources Information Center

Spiegler, Thomas

2010-01-01

Parents' motives for home education are one of the most researched topics within home education research. The focus of this article is on the question of the degree to which the results regarding these motives are influenced and shaped by the applied methods and the social context. The empirical basis is a meta-analysis of twelve research…

Correcting Fallacies in Validity, Reliability, and Classification

ERIC Educational Resources Information Center

Sijtsma, Klaas

2009-01-01

This article reviews three topics from test theory that continue to raise discussion and controversy and capture test theorists' and constructors' interest. The first topic concerns the discussion of the methodology of investigating and establishing construct validity; the second topic concerns reliability and its misuse, alternative definitions…

Recent advances in CE-MS coupling: Instrumentation, methodology, and applications.

PubMed

Týčová, Anna; Ledvina, Vojtěch; Klepárník, Karel

2017-01-01

This review focuses on the latest development of microseparation electromigration methods in capillaries and microfluidic devices coupled with MS for detection and identification of important analytes. It is a continuation of the review article on the same topic by Kleparnik (Electrophoresis 2015, 36, 159-178). A wide selection of 161 relevant articles covers the literature published from June 2014 till May 2016. New improvements in the instrumentation and methodology of MS interfaced with capillary or microfluidic versions of zone electrophoresis, isotachophoresis, and isoelectric focusing are described in detail. The most frequently implemented MS ionization methods include electrospray ionization, matrix-assisted desorption/ionization and inductively coupled plasma ionization. Although the main attention is paid to the development of instrumentation and methodology, representative examples illustrate also applications in the proteomics, glycomics, metabolomics, biomarker research, forensics, pharmacology, food analysis, and single-cell analysis. The combinations of MS with capillary versions of electrochromatography, and micellar electrokinetic chromatography are not included. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A Brief Introduction to Q Methodology

ERIC Educational Resources Information Center

Yang, Yang

2016-01-01

Q methodology is a method to systematically study subjective matters such as thoughts and beliefs on any given topic. Q methodology can be used for both theory building and theory testing. The purpose of this paper was to give a brief overview of Q methodology to readers with various backgrounds. This paper discussed several advantages of Q…

A Relevancy Algorithm for Curating Earth Science Data Around Phenomenon

NASA Technical Reports Server (NTRS)

Maskey, Manil; Ramachandran, Rahul; Li, Xiang; Weigel, Amanda; Bugbee, Kaylin; Gatlin, Patrick; Miller, J. J.

2017-01-01

Earth science data are being collected for various science needs and applications, processed using different algorithms at multiple resolutions and coverages, and then archived at different archiving centers for distribution and stewardship causing difficulty in data discovery. Curation, which typically occurs in museums, art galleries, and libraries, is traditionally defined as the process of collecting and organizing information around a common subject matter or a topic of interest. Curating data sets around topics or areas of interest addresses some of the data discovery needs in the field of Earth science, especially for unanticipated users of data. This paper describes a methodology to automate search and selection of data around specific phenomena. Different components of the methodology including the assumptions, the process, and the relevancy ranking algorithm are described. The paper makes two unique contributions to improving data search and discovery capabilities. First, the paper describes a novel methodology developed for automatically curating data around a topic using Earthscience metadata records. Second, the methodology has been implemented as a standalone web service that is utilized to augment search and usability of data in a variety of tools.

A relevancy algorithm for curating earth science data around phenomenon

NASA Astrophysics Data System (ADS)

Maskey, Manil; Ramachandran, Rahul; Li, Xiang; Weigel, Amanda; Bugbee, Kaylin; Gatlin, Patrick; Miller, J. J.

2017-09-01

Earth science data are being collected for various science needs and applications, processed using different algorithms at multiple resolutions and coverages, and then archived at different archiving centers for distribution and stewardship causing difficulty in data discovery. Curation, which typically occurs in museums, art galleries, and libraries, is traditionally defined as the process of collecting and organizing information around a common subject matter or a topic of interest. Curating data sets around topics or areas of interest addresses some of the data discovery needs in the field of Earth science, especially for unanticipated users of data. This paper describes a methodology to automate search and selection of data around specific phenomena. Different components of the methodology including the assumptions, the process, and the relevancy ranking algorithm are described. The paper makes two unique contributions to improving data search and discovery capabilities. First, the paper describes a novel methodology developed for automatically curating data around a topic using Earth science metadata records. Second, the methodology has been implemented as a stand-alone web service that is utilized to augment search and usability of data in a variety of tools.

Prioritizing qualitative research in surgery: A synthesis and analysis of publication trends.

PubMed

Maragh-Bass, Allysha C; Appelson, Jessica R; Changoor, Navin R; Davis, W Austin; Haider, Adil H; Morris, Megan A

2016-12-01

Over the past 2 decades, researchers have recognized the value of qualitative research. Little has been done to characterize its application to surgery. We describe characteristics and overall prevalence of qualitative surgical research. We searched PubMed and CINAHL using "surgery" and 7 qualitative methodology terms. Four researchers extracted information; a fifth researcher reviewed 10% of abstracts for inter-rater reliability. A total of 3,112 articles were reviewed. Removing duplicates, 28% were relevant (N = 878; κ = 0.70). Common qualitative methodologies included phenomenology (34.3%) and grounded theory (30.2%). Interviews were the most common data collection method (81.9%) of patients (64%) within surgical oncology (15.4%). Postdischarge was the most commonly studied topic (30.8%). Overall, 41% of studies were published in nursing journals, while 8% were published in surgical journals. More than half of studies were published since 2011. Results suggest qualitative surgical research is gaining popularity. Most is published in nonsurgical journals, however, utilizing only 2 methodologies (phenomenology, grounded theory). The surgical journals that have published qualitative research had study topics restricted to a handful of surgical specialties. Additional surgical qualitative research should take advantage of a greater variety of approaches to provide insight into rare phenomena and social context. Copyright © 2016 Elsevier Inc. All rights reserved.

Technology transfer methodology

NASA Technical Reports Server (NTRS)

Labotz, Rich

1991-01-01

Information on technology transfer methodology is given in viewgraph form. Topics covered include problems in economics, technology drivers, inhibitors to using improved technology in development, technology application opportunities, and co-sponsorship of technology.

The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis.

PubMed

Chen, Shubiao; Wu, Kezhou; Kong, Gengbin; Feng, Weili; Deng, Zhihua; Wang, Hu

2016-02-16

Topical tranexamic acid (TXA) has been shown to be effective in reducing blood loss and the need for transfusion after total knee arthroplasty. However, the effectiveness of topical TXA use in total hip arthroplasty (THA) still remains unclear. The purpose of this meta-analysis is to examine the safety and efficacy of topical use of TXA following THA. Topical TXA reduces blood loss and transfusion rates without increasing risk of deep vein thrombosis in patients with THA. An electronic literature search of PubMed, Embase, the Cochrane Library, Web of Science and Chinese Biomedical Database was performed, to identify studies published before February 2015. All randomized controlled trials and cohort studies evaluating the efficacy of topical TXA during THA were included. Two independent authors identified the eligible studies, assessed their methodological quality, and extracted data. The data were using fixed-effects or random-effects models with (standard) mean differences and risk ratios for continuous and dichotomous variables, respectively. Data were analysed using RevMan 5.3 software. Fourteen studies encompassing 2594 patients met the inclusion criteria for our meta-analysis. Our meta-analysis indicated that when compared with the placebo group, topical use of TXA significantly reduced total blood loss (MD = -297.65 ml, 95 % CI -371.68 ml, 116.08 ml; P < 0.01), drainage loss (MD = -164.68 ml, 95 % CI -236.63 ml, -92.73 ml; P < 0.01), transfusion rate (RR = 0.26, 95 % CI 0.17, 0.40; P < 0.01) and with less of a drop in haemoglobin level (SMD = -0.66, 95 % CI -0.91, -0.41; P < 0.01) after primary THA. No significant difference in length of hospital stay (MD = -0.40, 95 % CI -0.91, 0.11; P = 0.14), deep vein thrombosis (RR = 1.19, 95 % CI 0.40, 3.57; P = 0.16) and pulmonary embolism (RR = 1.11, 95 % CI 0.11, 10.81; P = 0.21) among the study groups. Topical TXA could significantly reduce total blood loss, drainage loss, transfusion rates and decrease haemoglobin level following THA, without increasing risk of venous thromboembolisms.

SNIF-ACT: A Cognitive Model of User Navigation on the World Wide Web

DTIC Science & Technology

2007-01-03

opinions of others on a particular topic or problems. Obviously, our model was not able to answer these questions directly, and more research is... Research Center 3333 Coyote Hill Rd Palo Alto, CA 94304, USA Manuscript submitted to Human-Computer Interaction Date: Jan 03, 2007...models. Rational analysis is a variant form of an approach called methodological adaptationism that has also shaped research programs in behavioral

"H TEXNH: Research Methods and Topics for the History of Rhetoric"; Proceedings of the Speech Communications Association Doctoral Honors Seminar (Ann Arbor, Michigan, March 3-5, 1978).

ERIC Educational Resources Information Center

Enos, Richard Leo, Ed.; Wiethoff, William E., Ed.

The interpretation of the history of rhetoric was the subject of the seminar reported in this document. After a preface and a discussion of the "promise" of rhetoric, abstracts of seminar presentations are grouped under the headings of rhetoric and culture, rhetoric and philosophy, methodological considerations, and discourse analysis.…

An Examination of Graduate Theses Related with Guitar in Terms of Methodology and Content: A Case of Turkey

ERIC Educational Resources Information Center

Yöndem, Sadik

2015-01-01

The aim of this study is to examine post-graduate thesis completed on guitar in Turkey. For this purpose, a total of 89 theses were investigated in terms of selected research topics, study participants, and methods for analysis. For the selection of the thesis included in this study three criteria were used; first, theses from 1990 (beginning time…

TRAC-Monterey FY16 Work Program Development and Report of Research Elicitation

DTIC Science & Technology

2016-01-01

any changes to priorities or additional projects that require immediate research. Work Program; Research Elicitation Unclassified UU UU UU UU 35 MAJ...conduct analysis for the Army. 1 Marks, Chris, Nesbitt, Peter. TRAC FY14 Research Requirements Elicitation . Technical Report TRAC-M-TM-13-059. 700 Dyer... Requirements Elicitation Interviews Interview Guide: 1. Describe a research requirement in the areas of topics, techniques, and methodologies. 2

Adding results to a meta-analysis: Theory and example

NASA Astrophysics Data System (ADS)

Willson, Victor L.

Meta-analysis has been used as a research method to describe bodies of research data. It promotes hypothesis formation and the development of science education laws. A function overlooked, however, is the role it plays in updating research. Methods to integrate new research with meta-analysis results need explication. A procedure is presented using Bayesian analysis. Research in science education attitude correlation with achievement has been published after a recent meta-analysis of the topic. The results show how new findings complement the previous meta-analysis and extend its conclusions. Additional methodological questions adddressed are how studies are to be weighted, which variables are to be examined, and how often meta-analysis are to be updated.

Tests of methods for evaluating bibliographic databases: an analysis of the National Library of Medicine's handling of literatures in the medical behavioral sciences.

PubMed

Griffith, B C; White, H D; Drott, M C; Saye, J D

1986-07-01

This article reports on five separate studies designed for the National Library of Medicine (NLM) to develop and test methodologies for evaluating the products of large databases. The methodologies were tested on literatures of the medical behavioral sciences (MBS). One of these studies examined how well NLM covered MBS monographic literature using CATLINE and OCLC. Another examined MBS journal and serial literature coverage in MEDLINE and other MBS-related databases available through DIALOG. These two studies used 1010 items derived from the reference lists of sixty-one journals, and tested for gaps and overlaps in coverage in the various databases. A third study examined the quality of the indexing NLM provides to MBS literatures and developed a measure of indexing as a system component. The final two studies explored how well MEDLINE retrieved documents on topics submitted by MBS professionals and how online searchers viewed MEDLINE (and other systems and databases) in handling MBS topics. The five studies yielded both broad research outcomes and specific recommendations to NLM.

Investigation of air transportation technology at Massachusetts Institute of Technology, 1985

NASA Technical Reports Server (NTRS)

Simpson, Robert W.

1987-01-01

Two areas of research are discussed, an investigation into runway approach flying with Loran C and a series of research topics in the development of experimental validation of methodologies to support aircraft icing analysis. Flight tests with the Loran C led to the conclusion that it is a suitable system for non-precision approaches, and that time-difference corrections made every eight weeks in the instrument approach plates will produce acceptable errors. In the area of aircraft icing analysis, wind tunnel and flight test results are discussed.

Medical device procurement in low- and middle-income settings: protocol for a systematic review.

PubMed

Diaconu, Karin; Chen, Yen-Fu; Manaseki-Holland, Semira; Cummins, Carole; Lilford, Richard

2014-10-21

Medical device procurement processes for low- and middle-income countries (LMICs) are a poorly understood and researched topic. To support LMIC policy formulation in this area, international public health organizations and research institutions issue a large body of predominantly grey literature including guidelines, manuals and recommendations. We propose to undertake a systematic review to identify and explore the medical device procurement methodologies suggested within this and further literature. Procurement facilitators and barriers will be identified, and methodologies for medical device prioritization under resource constraints will be discussed. Searches of both bibliographic and grey literature will be conducted to identify documents relating to the procurement of medical devices in LMICs. Data will be extracted according to protocol on a number of pre-specified issues and variables. First, data relating to the specific settings described within the literature will be noted. Second, information relating to medical device procurement methodologies will be extracted, including prioritization of procurement under resource constraints, the use of evidence (e.g. cost-effectiveness evaluations, burden of disease data) as well as stakeholders participating in procurement processes. Information relating to prioritization methodologies will be extracted in the form of quotes or keywords, and analysis will include qualitative meta-summary. Narrative synthesis will be employed to analyse data otherwise extracted. The PRISMA guidelines for reporting will be followed. The current review will identify recommended medical device procurement methodologies for LMICs. Prioritization methods for medical device acquisition will be explored. Relevant stakeholders, facilitators and barriers will be discussed. The review is aimed at both LMIC decision makers and the international research community and hopes to offer a first holistic conceptualization of this topic.

Medical device procurement in low- and middle-income settings: protocol for a systematic review

PubMed Central

2014-01-01

Background Medical device procurement processes for low- and middle-income countries (LMICs) are a poorly understood and researched topic. To support LMIC policy formulation in this area, international public health organizations and research institutions issue a large body of predominantly grey literature including guidelines, manuals and recommendations. We propose to undertake a systematic review to identify and explore the medical device procurement methodologies suggested within this and further literature. Procurement facilitators and barriers will be identified, and methodologies for medical device prioritization under resource constraints will be discussed. Methods/design Searches of both bibliographic and grey literature will be conducted to identify documents relating to the procurement of medical devices in LMICs. Data will be extracted according to protocol on a number of pre-specified issues and variables. First, data relating to the specific settings described within the literature will be noted. Second, information relating to medical device procurement methodologies will be extracted, including prioritization of procurement under resource constraints, the use of evidence (e.g. cost-effectiveness evaluations, burden of disease data) as well as stakeholders participating in procurement processes. Information relating to prioritization methodologies will be extracted in the form of quotes or keywords, and analysis will include qualitative meta-summary. Narrative synthesis will be employed to analyse data otherwise extracted. The PRISMA guidelines for reporting will be followed. Discussion The current review will identify recommended medical device procurement methodologies for LMICs. Prioritization methods for medical device acquisition will be explored. Relevant stakeholders, facilitators and barriers will be discussed. The review is aimed at both LMIC decision makers and the international research community and hopes to offer a first holistic conceptualization of this topic. PMID:25336161

GPS system simulation methodology

NASA Technical Reports Server (NTRS)

Ewing, Thomas F.

1993-01-01

The following topics are presented: background; Global Positioning System (GPS) methodology overview; the graphical user interface (GUI); current models; application to space nuclear power/propulsion; and interfacing requirements. The discussion is presented in vugraph form.

TOPICAL REVIEW: Human soft tissue analysis using x-ray or gamma-ray techniques

NASA Astrophysics Data System (ADS)

Theodorakou, C.; Farquharson, M. J.

2008-06-01

This topical review is intended to describe the x-ray techniques used for human soft tissue analysis. X-ray techniques have been applied to human soft tissue characterization and interesting results have been presented over the last few decades. The motivation behind such studies is to provide improved patient outcome by using the data obtained to better understand a disease process and improve diagnosis. An overview of theoretical background as well as a complete set of references is presented. For each study, a brief summary of the methodology and results is given. The x-ray techniques include x-ray diffraction, x-ray fluorescence, Compton scattering, Compton to coherent scattering ratio and attenuation measurements. The soft tissues that have been classified using x-rays or gamma rays include brain, breast, colon, fat, kidney, liver, lung, muscle, prostate, skin, thyroid and uterus.

Common Methodology for Efficient Airspace Operations

NASA Technical Reports Server (NTRS)

Sridhar, Banavar

2012-01-01

Topics include: a) Developing a common methodology to model and avoid disturbances affecting airspace. b) Integrated contrails and emission models to a national level airspace simulation. c) Developed capability to visualize, evaluate technology and alternate operational concepts and provide inputs for policy-analysis tools to reduce the impact of aviation on the environment. d) Collaborating with Volpe Research Center, NOAA and DLR to leverage expertise and tools in aircraft emissions and weather/climate modeling. Airspace operations is a trade-off balancing safety, capacity, efficiency and environmental considerations. Ideal flight: Unimpeded wind optimal route with optimal climb and descent. Operations degraded due to reduction in airport and airspace capacity caused by inefficient procedures and disturbances.

Systematic review of the evidence related to mandated nurse staffing ratios in acute hospitals.

PubMed

Olley, Richard; Edwards, Ian; Avery, Mark; Cooper, Helen

2018-04-17

Objective The purpose of this systematic review was to evaluate and summarise available research on nurse staffing methods and relate these to outcomes under three overarching themes of: (1) management of clinical risk, quality and safety; (2) development of a new or innovative staffing methodology; and (3) equity of nursing workload. Methods The PRISMA method was used. Relevant articles were located by searching via the Griffith University Library electronic catalogue, including articles on PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Medline. Only English language publications published between 1 January 2010 and 30 April 2016 focusing on methodologies in acute hospital in-patient units were included in the present review. Results Two of the four staffing methods were found to have evidenced-based articles from empirical studies within the parameters set for inclusion. Of the four staffing methodologies searched, supply and demand returned 10 studies and staffing ratios returned 11. Conclusions There is a need to develop an evidence-based nurse-sensitive outcomes measure upon which staffing for safety, quality and workplace equity, as well as an instrument that reliability and validly projects nurse staffing requirements in a variety of clinical settings. Nurse-sensitive indicators reflect elements of patient care that are directly affected by nursing practice In addition, these measures must take into account patient satisfaction, workload and staffing, clinical risks and other measures of the quality and safety of care and nurses' work satisfaction. i. What is known about the topic? Nurse staffing is a controversial topic that has significant patient safety, quality of care, human resources and financial implications. In acute care services, nursing accounts for approximately 70% of salaries and wages paid by health services budgets, and evidence as to the efficacy and effectiveness of any staffing methodology is required because it has workforce and industrial relations implications. Although there is significant literature available on the topic, there is a paucity of empirical evidence supporting claims of increased patient safety in the acute hospital setting, but some evidence exists relating to equity of workload for nurses. What does this paper add? This paper provides a contemporary qualitative analysis of empirical evidence using PRISMA methodology to conduct a systematic review of the available literature. It demonstrates a significant research gap to support claims of increased patient safety in the acute hospital setting. The paper calls for greatly improved datasets upon which research can be undertaken to determine any associations between mandated patient to nurse ratios and other staffing methodologies and patient safety and quality of care. What are the implications for practitioners? There is insufficient contemporary research to support staffing methodologies for appropriate staffing, balanced workloads and quality, safe care. Such research would include the establishment of nurse-sensitive patient outcomes measures, and more robust datasets are needed for empirical analysis to produce such evidence.

77 FR 50514 - Post-Approval Studies 2012 Workshop: Design, Methodology, and Role in Evidence Appraisal...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-21

...] Post-Approval Studies 2012 Workshop: Design, Methodology, and Role in Evidence Appraisal Throughout the... Administration (FDA) is announcing the following public workshop entitled ``Post-Approval Studies 2012 Workshop: Design, Methodology, and Role in Evidence Appraisal Throughout the Total Product Life Cycle.'' The topics...

Determining The Various Perspectives And Consensus Within A Classroom Using Q Methodology

NASA Astrophysics Data System (ADS)

Ramlo, Susan E.

2008-10-01

Q methodology was developed by PhD physicist and psychologist William Stevenson 73 years ago as a new way of investigating people's views of any topic. Yet its application has primarily been in the fields of marketing, psychology, and political science. Still, Q offers an opportunity for the physics education research community to determine the perspectives and consensus within a group, such as a classroom, related to topics of interest such as the nature of science and epistemology. This paper presents the basics of using Q methodology with a classroom application as an example and subsequent comparisons of this example's results to similar studies using qualitative and survey methods.

Determining if disease management saves money: an introduction to meta-analysis.

PubMed

Linden, Ariel; Adams, John L

2007-06-01

Disease management (DM) programmes have long been promoted as a major medical cost-saving mechanism, even though the scant research that exists on the topic has provided conflicting results. In a 2004 literature review, the Congressional Budget Office stated that 'there is insufficient evidence to conclude that disease management programs can generally reduce the overall cost of health care services'. To address this question more accurately, a meta-analysis was warranted. Meta-analysis is the quantitative technique used to pool the results of many studies on the same topic and summarize them statistically. This method is also quite suitable for individual DM firms to assess whether their programmes are effective at the aggregate level. This paper describes the elements of a rigorous meta-analytic process and discusses potential biases. A hypothetical DM organization is then evaluated with a specific emphasis on medical cost-savings, simulating a case in which different populations are served, evaluation methodologies are employed, and diseases are managed.

The value of a statistical life: a meta-analysis with a mixed effects regression model.

PubMed

Bellavance, François; Dionne, Georges; Lebeau, Martin

2009-03-01

The value of a statistical life (VSL) is a very controversial topic, but one which is essential to the optimization of governmental decisions. We see a great variability in the values obtained from different studies. The source of this variability needs to be understood, in order to offer public decision-makers better guidance in choosing a value and to set clearer guidelines for future research on the topic. This article presents a meta-analysis based on 39 observations obtained from 37 studies (from nine different countries) which all use a hedonic wage method to calculate the VSL. Our meta-analysis is innovative in that it is the first to use the mixed effects regression model [Raudenbush, S.W., 1994. Random effects models. In: Cooper, H., Hedges, L.V. (Eds.), The Handbook of Research Synthesis. Russel Sage Foundation, New York] to analyze studies on the value of a statistical life. We conclude that the variability found in the values studied stems in large part from differences in methodologies.

Studying Sex: A Content Analysis of Sexuality Research in Counseling Psychology

PubMed Central

Crowell, Candice; Mosley, Della V.; Stevens-Watkins, Danelle

2016-01-01

Using a sex positive framework, the authors conducted a 61-year (1954–2015) content analysis of sexuality research in the flagship counseling psychology journals, the Journal of Counseling Psychology and The Counseling Psychologist. Given counseling psychology’s core strengths- and multiculturalism-related values, this study aimed to uncover which human sexuality topics were published most, whether publications aligned with a sex positive, neutral, or negative discourse, what methodologies were used, and differences in how populations were investigated across race. Researchers used an integrative approach to content analysis and human coding (Neuendorf, 2011). Results highlighted that out of 188 articles meeting criteria, a slight majority (38.05%) focused on sexual orientation, identity, and minorities topics. Only 4.78% utilized a sex-positive perspective. Quantitative and conceptual pieces were most published, and publications disproportionately focused on primarily White populations. When people of color were included, the discourse was sex negative. Implications for research and practice are discussed. PMID:28867823

Evaluation of health information systems research in information systems research: A meta-analysis.

PubMed

Haried, Peter; Claybaugh, Craig; Dai, Hua

2017-04-01

Given the importance of the health-care industry and the promise of health information systems, researchers are encouraged to build on the shoulders of giants as the saying goes. The health information systems field has a unique opportunity to learn from and extend the work that has already been done by the highly correlated information systems field. As a result, this research article presents a past, present and future meta-analysis of health information systems research in information systems journals over the 2000-2015 time period. Our analysis reviewed 126 articles on a variety of topics related to health information systems research published in the "Senior Scholars" list of the top eight ranked information systems academic journals. Across the selected information systems academic journals, our findings compare research methodologies applied, health information systems topic areas investigated and research trends. Interesting results emerge in the range and evolution of health information systems research and opportunities for health information systems researchers and practitioners to consider moving forward.

The effectiveness of the bone bridge transtibial amputation technique: A systematic review of high-quality evidence.

PubMed

Kahle, Jason T; Highsmith, M Jason; Kenney, John; Ruth, Tim; Lunseth, Paul A; Ertl, Janos

2017-06-01

This literature review was undertaken to determine if commonly held views about the benefits of a bone bridge technique are supported by the literature. Four databases were searched for articles pertaining to surgical strategies specific to a bone bridge technique of the transtibial amputee. A total of 35 articles were identified as potential articles. Authors included methodology that was applied to separate topics. Following identification, articles were excluded if they were determined to be low quality evidence or not pertinent. Nine articles were identified to be pertinent to one of the topics: Perioperative Care, Acute Care, Subjective Analysis and Function. Two articles sorted into multiple topics. Two articles were sorted into the Perioperative Care topic, 4 articles sorted into the Acute Care topic, 2 articles into the Subjective Analysis topic and 5 articles into the Function topic. There are no high quality (level one or two) clinical trials reporting comparisons of the bone bridge technique to traditional methods. There is limited evidence supporting the clinical outcomes of the bone bridge technique. There is no agreement supporting or discouraging the perioperative and acute care aspects of the bone bridge technique. There is no evidence defining an interventional comparison of the bone bridge technique. Current level III evidence supports a bone bridge technique as an equivalent option to the non-bone bridge transtibial amputation technique. Formal level I and II clinical trials will need to be considered in the future to guide clinical practice. Clinical relevance Clinical Practice Guidelines are evidence based. This systematic literature review identifies the highest quality evidence to date which reports a consensus of outcomes agreeing bone bridge is as safe and effective as alternatives. The clinical relevance is understanding bone bridge could additionally provide a mechanistic advantage for the transtibial amputee.

Do topical applications of bisphosphonates improve bone formation in oral implantology? A systematic review

PubMed Central

Lozano-Carrascal, Naroa; Hernández-Alfaro, Federico; Gehrke, Sergio-Alexandre; Gargallo-Albiol, Jordi; Calvo-Guirado, José-Luis

2017-01-01

Background The aim of this systematic literature review was to evaluate the feasibility of topical bisphosphonate application for preserving/enhancing alveolar bone in oral implantology. Material and Methods An electronic search was conducted in the PubMed/Medline, EMBASE, Scopus, Web of knowledge, and Google-Scholar databases for articles dated from January 2000 to December 2016. Two reviewers assessed the quality of the studies independently. Results A total of 154 abstracts were identified, of which 18 potentially relevant articles were selected; a final total of nine papers were included for analysis. Comparison of the findings of the selected studies was made difficult by the heterogeneity of the articles, all of them animal research papers that showed heterogeneity in the methodologies used and a high or moderate risk of bias. Conclusions The topical application of bisphosphonate solution would appear to favor new bone formation in alveolar defects, and boosts the regenerative capacities of biomaterials resulting in increased bone density. Key words:Alveolar bone, bone regeneration, topical application, biomaterial, bisphosphonates. PMID:28624840

Plant extracts for the topical management of psoriasis: a systematic review and meta-analysis.

PubMed

Deng, S; May, B H; Zhang, A L; Lu, C; Xue, C C L

2013-10-01

Patients with psoriasis frequently use preparations of plant extracts. Physicians need to be aware of the current evidence concerning these products. This review evaluates the efficacy and safety of preparations of plant extracts used topically for psoriasis. Searches were conducted in PubMed, Embase, the Cochrane library, two Chinese databases and article reference lists. Randomized controlled trials investigating extracts of single plants were included. Preparations of multiple plants and combinations of plant extracts plus conventional therapies were excluded. Two authors conducted searches, extracted data and assessed risk of bias. Outcomes used in meta-analyses were: clinical efficacy, Psoriasis Area and Severity Index score, and quality of life and symptom scores. The 12 included studies investigated extracts of: Mahonia aquifolium (n = 5), Aloe vera (n = 3), indigo naturalis (n = 2), kukui nut oil (n = 1) and Camptotheca acuminata nut (n = 1). Methodological quality was variable. Six studies provided data suitable for meta-analysis of clinical efficacy, and five were vs. placebo (relative risk 3·37, 95% confidence interval 1·36-8·33). Experimental studies indicate components of indigo naturalis, Mahonia and Camptotheca have anti-inflammatory, antiproliferative and other actions of relevance to psoriasis. The clinical trial evidence provides limited support for preparations containing extracts of M. aquifolium, indigo naturalis and Aloe vera for the topical management of plaque psoriasis based on multiple studies. No serious adverse events were reported. Because of the small size of most studies and methodological weaknesses, strong conclusions cannot be made. The magnitudes of any effects cannot be measured with accuracy, so it is difficult to assess the clinical relevance of these preparations. © 2013 British Association of Dermatologists.

Political Transformation and Research Methodology in Doctoral Education

ERIC Educational Resources Information Center

Herman, Chaya

2010-01-01

This paper examines the relationship between political change and epistemologies and methodologies employed at doctorate level. It does so by analysing the range of topics, questions and methodologies used by doctoral students at the University of Pretoria's Faculty of Education between 1985 and 2005--a time-frame that covers the decade before and…

Publication Bias in Methodological Computational Research.

PubMed

Boulesteix, Anne-Laure; Stierle, Veronika; Hapfelmeier, Alexander

2015-01-01

The problem of publication bias has long been discussed in research fields such as medicine. There is a consensus that publication bias is a reality and that solutions should be found to reduce it. In methodological computational research, including cancer informatics, publication bias may also be at work. The publication of negative research findings is certainly also a relevant issue, but has attracted very little attention to date. The present paper aims at providing a new formal framework to describe the notion of publication bias in the context of methodological computational research, facilitate and stimulate discussions on this topic, and increase awareness in the scientific community. We report an exemplary pilot study that aims at gaining experiences with the collection and analysis of information on unpublished research efforts with respect to publication bias, and we outline the encountered problems. Based on these experiences, we try to formalize the notion of publication bias.

Constructing post-surgical discharge instructions through a Delphi consensus methodology.

PubMed

Scott, Aaron R; Sanderson, Cody J; Rush, Augustus J; Alore, Elizabeth A; Naik, Aanand D; Berger, David H; Suliburk, James W

2018-05-01

Patient education materials are a crucial part of physician-patient communication. We hypothesize that available discharge instructions are difficult to read and fail to address necessary topics. Our objective is to evaluate readability and content of surgical discharge instructions using thyroidectomy to develop standardized discharge materials. Thyroidectomy discharge materials were analyzed for readability and assessed for content. Fifteen endocrine surgeons participated in a modified Delphi consensus panel to select necessary topics. Using readability best practices, we created standardized discharge instructions which included all selected topics. The panel evaluated 40 topics, selected 23, deemed 4 inappropriate, consolidated 5, and did not reach consensus on 8 topics after 4 rounds. The evaluated instructions' reading levels ranged from grade 6.5 to 13.2; none contained all consensus topics. Current post surgical thyroidectomy discharge instructions are more difficult to read than recommended by literacy standards and omit consensus warning signs of major complications. Our easy-to-read discharge instructions cover pertinent topics and may enhance patient education. Delphi methodology is useful for developing post-surgical instructions. Patient education materials need appropriate readability levels and content. We recommend the Delphi method to select content using consensus expert opinion whenever higher level data is lacking. Copyright © 2017 Elsevier B.V. All rights reserved.

Structure and dynamics of European sports science textual contents: Analysis of ECSS abstracts (1996-2014).

PubMed

Hristovski, Robert; Aceski, Aleksandar; Balague, Natalia; Seifert, Ludovic; Tufekcievski, Aleksandar; Cecilia, Aguirre

2017-02-01

The article discusses general structure and dynamics of the sports science research content as obtained from the analysis of 21998 European College of Sport Science abstracts belonging to 12 science topics. The structural analysis showed intertwined multidisciplinary and unifying tendencies structured along horizontal (scope) and vertical (level) axes. Methodological (instrumental and mode of inquiry) integrative tendencies are dominant. Theoretical integrative tendencies are much less detectable along both horizontal and vertical axes. The dynamic analysis of written abstracts text content over the 19 years reveals the contextualizing and guiding role of thematic skeletons of each sports science topic in forming more detailed contingent research ideas and the role of the latter in stabilizing and procreating the former. This circular causality between both hierarchical levels and functioning on separate characteristic time scales is crucial for understanding how stable research traditions self-maintain and self-procreate through innovative contingencies. The structure of sports science continuously rebuilds itself through use and re-use of contingent research ideas. The thematic skeleton ensures its identity and the contingent conceptual sets its flexibility and adaptability to different research or applicative problems.

DNA Sequencing in Cultural Heritage.

PubMed

Vai, Stefania; Lari, Martina; Caramelli, David

2016-02-01

During the last three decades, DNA analysis on degraded samples revealed itself as an important research tool in anthropology, archaeozoology, molecular evolution, and population genetics. Application on topics such as determination of species origin of prehistoric and historic objects, individual identification of famous personalities, characterization of particular samples important for historical, archeological, or evolutionary reconstructions, confers to the paleogenetics an important role also for the enhancement of cultural heritage. A really fast improvement in methodologies in recent years led to a revolution that permitted recovering even complete genomes from highly degraded samples with the possibility to go back in time 400,000 years for samples from temperate regions and 700,000 years for permafrozen remains and to analyze even more recent material that has been subjected to hard biochemical treatments. Here we propose a review on the different methodological approaches used so far for the molecular analysis of degraded samples and their application on some case studies.

A comparison of HAS & NICE guidelines for the economic evaluation of health technologies in the context of their respective national health care systems and cultural environments

PubMed Central

Massetti, Marc; Aballéa, Samuel; Videau, Yann; Rémuzat, Cécile; Roïz, Julie; Toumi, Mondher

2015-01-01

Background Health technology assessment (HTA) has been reinforced in France, notably with the introduction of economic evaluation in the pricing process for the most innovative and expensive treatments. Similarly to the National Institute for Clinical Excellence (NICE) in England, the National Authority for Health (HAS), which is responsible for economic evaluation of new health technologies in France, has published recommendations on the methods of economic evaluation. Since economic assessment represents a major element of HTA in England, exploring the differences between these methodological guidelines might help to comprehend both the shape and the role economic assessment is intended to have in the French health care system. Methods Methodological guidelines for economic evaluation in France and England have been compared topic-by-topic in order to bring out key differences in the recommended methods for economic evaluation. Results The analysis of both guidelines has revealed multiple similarities between France and England, although a number of differences were also noted regarding the elected methodology of analysis, the comparison of studies’ outcomes with cost-effectiveness thresholds, the study population to consider, the quality of life valuation methods, the perspective on costs, the types of resources considered and their valuation, the discount rates to apply in order to reflect the present value of interventions, etc. To account for these differences, modifications will be required in order to adapt economic models from one country to the other. Conclusions Changes in HTA assessment methods occur in response to different challenges determined by the different philosophical and cultural considerations surrounding health and welfare as well as the political considerations regarding the role of public policies and the importance of their evaluation. PMID:27123190

Satellite DNA: An Evolving Topic

PubMed Central

Garrido-Ramos, Manuel A.

2017-01-01

Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a lot of literature has extensively covered various topics related to the structure, organization, function, and evolution of such sequences. Today, with the advent of genomic tools, the study of satellite DNA has regained a great interest. Thus, Next-Generation Sequencing (NGS), together with high-throughput in silico analysis of the information contained in NGS reads, has revolutionized the analysis of the repetitive fraction of the eukaryotic genomes. The whole of the historical and current approaches to the topic gives us a broad view of the function and evolution of satellite DNA and its role in chromosomal evolution. Currently, we have extensive information on the molecular, chromosomal, biological, and population factors that affect the evolutionary fate of satellite DNA, knowledge that gives rise to a series of hypotheses that get on well with each other about the origin, spreading, and evolution of satellite DNA. In this paper, I review these hypotheses from a methodological, conceptual, and historical perspective and frame them in the context of chromosomal organization and evolution. PMID:28926993

Advanced stimulation technology deployment program: Sonat Exploration Company, Haynesville Formation, North Shongaloo, Red Rock Field, Columbia County, Arkansas and Webster Parish, Louisiana. Topical report, August 1995-January 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Skees, J.L.; Middlebrook, M.L.; Anthony, W.L.

1997-01-01

The objective of this program is to transfer the core GRI advanced stimulation technologies to Sonat Exploration Company for their continued use upon completion of the program. The methodology to accomplish the objective included seminars and training schools, offset well baseline analysis, fracture treatment design optimization, real-time and post-fracture treatment evaluation and documentation of economic benefits.

The Theory and Practice of Genre Criticism: Genre Criticism: The Analysis of Form, Part I; Genre Criticism: Judgment Argument and Evidence, Part II; [and] Genre Criticism: A Topical Bibliography, Part III.

ERIC Educational Resources Information Center

Creps, Earl

A three-part study of the forms of rhetorical criticism is offered. Part one reviews the nature of genre criticism, enumerates several concepts of form and the types of genre criticism they produce, and discusses the implications of this relationship between form and genre. Part two is an essay on the methodological implications of form-grounded…

Review of Research on School Principal Leadership in Mainland China, 1998-2013: Continuity and Change

ERIC Educational Resources Information Center

Walker, Allan; Qian, Haiyan

2015-01-01

Purpose: The purpose of this paper is to review English-language publications about school principalship in China published between 1998 and 2013 and to present an overview of the authorship, topics, methodologies and key findings of these publications. Design/methodology/approach: The methodology includes an exhaustive review of journal articles…

Temporal Methods to Detect Content-Based Anomalies in Social Media

DOE Office of Scientific and Technical Information (OSTI.GOV)

Skryzalin, Jacek; Field, Jr., Richard; Fisher, Andrew N.

Here, we develop a method for time-dependent topic tracking and meme trending in social media. Our objective is to identify time periods whose content differs signifcantly from normal, and we utilize two techniques to do so. The first is an information-theoretic analysis of the distributions of terms emitted during different periods of time. In the second, we cluster documents from each time period and analyze the tightness of each clustering. We also discuss a method of combining the scores created by each technique, and we provide ample empirical analysis of our methodology on various Twitter datasets.

Some comments on Hurst exponent and the long memory processes on capital markets

NASA Astrophysics Data System (ADS)

Sánchez Granero, M. A.; Trinidad Segovia, J. E.; García Pérez, J.

2008-09-01

The analysis of long memory processes in capital markets has been one of the topics in finance, since the existence of the market memory could implicate the rejection of an efficient market hypothesis. The study of these processes in finance is realized through Hurst exponent and the most classical method applied is R/S analysis. In this paper we will discuss the efficiency of this methodology as well as some of its more important modifications to detect the long memory. We also propose the application of a classical geometrical method with short modifications and we compare both approaches.

[Photography as analysis document, body and medicine: theory, method and criticism--the experience of Museo Nacional de Medicina Enrique Laval].

PubMed

Robinson, César Leyton; Caballero, Andrés Díaz

2007-01-01

This article is an experimental methodological reflection on the use of medical images as useful documents for constructing the history of medicine. A method is used that is based on guidelines or analysis topics that include different ways of viewing documents, from aesthetic, technical, social and political theories to historical and medical thinking. Some exercises are also included that enhance the proposal for the reader: rediscovering the worlds in society that harbor these medical photographical archives to obtain a new theoretical approach to the construction of the history of medical science.

Lessons learned from IDeAl - 33 recommendations from the IDeAl-net about design and analysis of small population clinical trials.

PubMed

Hilgers, Ralf-Dieter; Bogdan, Malgorzata; Burman, Carl-Fredrik; Dette, Holger; Karlsson, Mats; König, Franz; Male, Christoph; Mentré, France; Molenberghs, Geert; Senn, Stephen

2018-05-11

IDeAl (Integrated designs and analysis of small population clinical trials) is an EU funded project developing new statistical design and analysis methodologies for clinical trials in small population groups. Here we provide an overview of IDeAl findings and give recommendations to applied researchers. The description of the findings is broken down by the nine scientific IDeAl work packages and summarizes results from the project's more than 60 publications to date in peer reviewed journals. In addition, we applied text mining to evaluate the publications and the IDeAl work packages' output in relation to the design and analysis terms derived from in the IRDiRC task force report on small population clinical trials. The results are summarized, describing the developments from an applied viewpoint. The main result presented here are 33 practical recommendations drawn from the work, giving researchers a comprehensive guidance to the improved methodology. In particular, the findings will help design and analyse efficient clinical trials in rare diseases with limited number of patients available. We developed a network representation relating the hot topics developed by the IRDiRC task force on small population clinical trials to IDeAl's work as well as relating important methodologies by IDeAl's definition necessary to consider in design and analysis of small-population clinical trials. These network representation establish a new perspective on design and analysis of small-population clinical trials. IDeAl has provided a huge number of options to refine the statistical methodology for small-population clinical trials from various perspectives. A total of 33 recommendations developed and related to the work packages help the researcher to design small population clinical trial. The route to improvements is displayed in IDeAl-network representing important statistical methodological skills necessary to design and analysis of small-population clinical trials. The methods are ready for use.

Standardization of an in vitro Model for Evaluating the Bioavailability of Topically Applied Compounds on Damaged Skin: Application to Sunscreen Analysis.

PubMed

Jacques-Jamin, Carine; Jeanjean-Miquel, Corinne; Domergue, Anaïs; Bessou-Touya, Sandrine; Duplan, Hélène

2017-01-01

Information is lacking on the dermal penetration of topically applied formulations on in vitro skin models, under conditions where the stratum corneum (SC) is damaged. Therefore, we have developed a standardized in vitro barrier-disrupted skin model using tape stripping. Different tape stripping conditions were evaluated using histology, transepidermal water loss, infrared densitometry, and caffeine absorption. The effects of tape stripping were comparable using pig and human skin. Optimized conditions were used to test the effect of SC damage and UV irradiation on the absorption of an UV filter combination present in a sunscreen. The bioavailability of the filters was extremely low regardless of the extent of skin damage, suggesting bioavailability would not be increased if the consumer applied the sunscreen to sun-damaged skin. This standardized in vitro methodology using pig or human skin for damaged skin will add valuable information for the safety assessment of topically applied products. © 2017 S. Karger AG, Basel.

Methodological and ethical issues related to qualitative telephone interviews on sensitive topics.

PubMed

Mealer, Meredith; Jones Rn, Jacqueline

2014-03-01

To explore the methodological and ethical issues of conducting qualitative telephone interviews about personal or professional trauma with critical care nurses. The most common method for conducting interviews is face-to-face. However, there is evidence to support telephone interviewing on a variety of sensitive topics including post-traumatic stress disorder (PTSD). Qualitative telephone interviews can limit emotional distress because of the comfort experienced through virtual communication. Critical care nurses are at increased risk of developing PTSD due to the cumulative exposure to work-related stress in the intensive care unit. We explored the methodological and ethical issues of conducting qualitative telephone interviews, drawing on our experiences communicating with a group of critical care nurses. Qualitative research interviews with 27 critical care nurses. Fourteen of the nurses met the diagnostic criteria for PTSD; 13 did not and had scores consistent with high levels of resilience. This is a methodology paper on the authors' experiences of interviewing critical care nurses on sensitive topics via the telephone. The authors found that establishing rapport and connections with the participants and the therapeutic use of non-verbal communication were essential, and fostered trust and compassion. The ethical issues of this mode of communication include protecting the privacy and confidentiality associated with the disclosure of sensitive information, and minimising the risk of psychological harm to the researcher and participants. Qualitative telephone interviews are a valuable method of collecting information on sensitive topics. This paper explores a method of interviewing in the workplace. It will help inform interventions to promote healthy adaptation following trauma exposure in the intensive care unit.

Practice variation amongst preventive child healthcare professionals in the prevention of child maltreatment in the Netherlands: Qualitative and quantitative data.

PubMed

Visscher, Simeon J A; van Stel, Henk F

2017-12-01

This article provides both qualitative and quantitative data on practice variation amongst preventive child healthcare professionals in the prevention of child maltreatment in the Netherlands. Qualitative data consist of topics identified during interviews with 11 experts (with quotes), resulting in an online survey. The quantitative data are survey responses from 1104 doctors and nurses working in 29 preventive child healthcare organizations. Additionally, the interview topic list, the qualitative data analysis methodology, the survey (in English and Dutch) and anonymized raw survey data (http://hdl.handle.net/10411/5LJOGH) are provided as well. This data-in-brief article accompanies the paper "Variation in prevention of child maltreatment by Dutch child healthcare professionals" by Simeon Visscher and Henk van Stel [1].

Vygotsky's Methodological Contribution to Sociocultural Theory.

ERIC Educational Resources Information Center

Mahn, Holbrook

1999-01-01

This article introduces major contributions of educational psychologist, Lev S. Vygotsky, through examination of his dialectical methodological approach. Topics discussed include semiotic mediation, social sources of development, verbal thinking, concept formation, spontaneous and scientific concepts, the zone of proximal development, and higher…

Hot Topics: Value of Solar | State, Local, and Tribal Governments | NREL

Science.gov Websites

, including what it is, how it is developed, and which methodologies are being used in the marketplace. VOS in methodologies that in are currently in place. The information presented in this podcast is based

Mapping texts through dimensionality reduction and visualization techniques for interactive exploration of document collections

NASA Astrophysics Data System (ADS)

de Andrade Lopes, Alneu; Minghim, Rosane; Melo, Vinícius; Paulovich, Fernando V.

2006-01-01

The current availability of information many times impair the tasks of searching, browsing and analyzing information pertinent to a topic of interest. This paper presents a methodology to create a meaningful graphical representation of documents corpora targeted at supporting exploration of correlated documents. The purpose of such an approach is to produce a map from a document body on a research topic or field based on the analysis of their contents, and similarities amongst articles. The document map is generated, after text pre-processing, by projecting the data in two dimensions using Latent Semantic Indexing. The projection is followed by hierarchical clustering to support sub-area identification. The map can be interactively explored, helping to narrow down the search for relevant articles. Tests were performed using a collection of documents pre-classified into three research subject classes: Case-Based Reasoning, Information Retrieval, and Inductive Logic Programming. The map produced was capable of separating the main areas and approaching documents by their similarity, revealing possible topics, and identifying boundaries between them. The tool can deal with the exploration of inter-topics and intra-topic relationship and is useful in many contexts that need deciding on relevant articles to read, such as scientific research, education, and training.

Using questions sent to an Ask-A-Scientist site to identify children's interests in science

NASA Astrophysics Data System (ADS)

Baram-Tsabari, Ayelet; Sethi, Ricky J.; Bry, Lynn; Yarden, Anat

2006-11-01

Interest is a powerful motivator; nonetheless, science educators often lack the necessary information to make use of the power of student-specific interests in the reform process of science curricula. This study suggests a novel methodology, which might be helpful in identifying such interests - using children's self-generated questions as an indication of their scientific interests. In this research, children's interests were measured by analyzing 1555 science-related questions submitted to an international Ask-A-Scientist Internet site. The analysis indicated that the popularity of certain topics varies with age and gender. Significant differences were found between children's spontaneous (intrinsically motivated) and school-related (extrinsically motivated) interests. Surprisingly, girls contributed most of the questions to the sample; however, the number of American girls dropped upon entering senior high school. We also found significant differences between girls' and boys' interests, with girls generally preferring biological topics. The two genders kept to their stereotypic fields of interest, in both their school-related and spontaneous questions. Children's science interests, as inferred from questions to Web sites, could ultimately inform classroom science teaching. This methodology extends the context in which children's interests can be investigated.

Methodology for Benefit Analysis of CAD/CAM (Computer-Aided Design/Computer-Aided Manufacturing) in USN Shipyards.

DTIC Science & Technology

1984-03-01

difference calcula- tion, would result in erroneously lower productivity ratios. Only two topics are not adequately addressed with the method --the first...for determination of this term. 3. CAIDQS P.22li y §easuI~gZ._ Jelbo The next method differs significantly from the previous two in that it deals with...Chasen’s Method (as applied by Lonq Beach M.S.) . . . . . . . o . o . . . . . 31 2. Shah G Yans Method . . . . . . . . . . . 34 3. CARDOS Productivity

Applications of artificial intelligence V; Proceedings of the Meeting, Orlando, FL, May 18-20, 1987

NASA Technical Reports Server (NTRS)

Gilmore, John F. (Editor)

1987-01-01

The papers contained in this volume focus on current trends in applications of artificial intelligence. Topics discussed include expert systems, image understanding, artificial intelligence tools, knowledge-based systems, heuristic systems, manufacturing applications, and image analysis. Papers are presented on expert system issues in automated, autonomous space vehicle rendezvous; traditional versus rule-based programming techniques; applications to the control of optional flight information; methodology for evaluating knowledge-based systems; and real-time advisory system for airborne early warning.

F-16XL-2 Supersonic Laminar Flow Control Flight Test Experiment

NASA Technical Reports Server (NTRS)

Anders, Scott G.; Fischer, Michael C.

1999-01-01

The F-16XL-2 Supersonic Laminar Flow Control Flight Test Experiment was part of the NASA High-Speed Research Program. The goal of the experiment was to demonstrate extensive laminar flow, to validate computational fluid dynamics (CFD) codes and design methodology, and to establish laminar flow control design criteria. Topics include the flight test hardware and design, airplane modification, the pressure and suction distributions achieved, the laminar flow achieved, and the data analysis and code correlation.

Towards a Comprehensive Approach to the Analysis of Categorical Data.

DTIC Science & Technology

1983-06-01

have made methodological contributions to the topic include R.L. Anderson, K. Hinkelman, 0. Kempthorne, and K. Koehler . The next section of this paper...their sufficient statistics that originated in the 1930’s with Fisher (e.g. see Dempster, 1971, and the discussion in Andersen. 1980 ). From the...ones from the original density for which h, h, .... h are MSS’s, and h ,h. h are the corresponding MSS’s in the conditional density (see Andersen, 1980

Design requirements for SRB production control system. Volume 3: Package evaluation, modification and hardware

NASA Technical Reports Server (NTRS)

1981-01-01

The software package evaluation was designed to analyze commercially available, field-proven, production control or manufacturing resource planning management technology and software package. The analysis was conducted by comparing SRB production control software requirements and conceptual system design to software package capabilities. The methodology of evaluation and the findings at each stage of evaluation are described. Topics covered include: vendor listing; request for information (RFI) document; RFI response rate and quality; RFI evaluation process; and capabilities versus requirements.

Expert systems in transmission planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galiana, F.D.; McGillis, D.T.; Marin, M.A.

1992-05-01

In this paper the state of the field of expert systems and knowledge engineering in transmission planning is reviewed. A detailed analysis of the goals, definition, requirements and methodology of transmission planning is presented. Potential benefits of knowledge-based applications in transmission planning are reviewed. This is followed by a thorough review of the area broken down into subareas or important related topics. The conclusions offer a number of suggestions for possible future research and development. Finally, a detailed bibliography divided into subareas is presented.

Relevance and Retrieval Evaluation: Perspectives from Medicine.

ERIC Educational Resources Information Center

Hersh, William

1994-01-01

Discusses topical relevance and situational relevance, which takes into account the impact of the retrieval system on the user, in the context of medicine. Topics addressed include scientific validity; limitations of current evaluation methodology, including recall and precision; and a framework for future retrieval research based on an…

[Scientific and methodologic approaches to evaluating medical management for workers of Kazakhstan].

PubMed

2012-01-01

The article covers topical problems of workers' health preservation. Complex research results enabled to evaluate and analyze occupational risks in leading industries of Kazakhstan, for improving scientific and methodologic approaches to medical management for workers subjected to hazardous conditions.

Handbook of Reading Research.

ERIC Educational Resources Information Center

Pearson, P. David, Ed.; And Others

Intended for reading educators and researchers, this handbook characterizes the current state of methodology and the cumulative research-based knowledge of reading. The book's three sections cover methodological issues, basic reading processes, and instructional practices. The 25 chapters discuss the following topics: (1) reading research history,…

[Quantity versus quality: a review on current methodological dispute in health services research].

PubMed

Sikorski, Claudia; Glaesmer, Heide; Bramesfeld, Anke

2010-10-01

The aim of this study was to determine the percentage of qualitative and quantitative research papers on health services research in two German journals. All publications of the two journals were viewed. Only empirical research papers were included. It was then assessed whether they dealt with health services research and what methodology was used to collect and analyse data. About half of all published empirical papers dealt with health services research. Of those, slightly over 20 % used qualitative methods at least partially. Ordered by topic, qualitative data collection and analysis is especially common in the fields of phenomenology, treatment determinants and treatment outcome. Sole qualitative methodology is still used rather seldom in health services research. Attempts to include quantitative as well as qualitative approaches are limited to sequential design, lowering the independent value of both approaches. The concept of triangulation yields the possibility to overcome paradigm based dichotomies. However, the choice of methodology ought to be based primarily on the research question. © Georg Thieme Verlag KG Stuttgart · New York.

Quantitative Analysis of the Interdisciplinarity of Applied Mathematics.

PubMed

Xie, Zheng; Duan, Xiaojun; Ouyang, Zhenzheng; Zhang, Pengyuan

2015-01-01

The increasing use of mathematical techniques in scientific research leads to the interdisciplinarity of applied mathematics. This viewpoint is validated quantitatively here by statistical and network analysis on the corpus PNAS 1999-2013. A network describing the interdisciplinary relationships between disciplines in a panoramic view is built based on the corpus. Specific network indicators show the hub role of applied mathematics in interdisciplinary research. The statistical analysis on the corpus content finds that algorithms, a primary topic of applied mathematics, positively correlates, increasingly co-occurs, and has an equilibrium relationship in the long-run with certain typical research paradigms and methodologies. The finding can be understood as an intrinsic cause of the interdisciplinarity of applied mathematics.

Black Adolescence: Topical Summaries and Annotated Bibliographies of Research.

ERIC Educational Resources Information Center

Consortium for Research on Black Adolescence, Storrs, CT.

A review of studies on black youth indicates a need for more attention to research concerns such as theory development, carefully constructed methodologies, and sensitivity to the interrelatedness among and between demographic variables. Some topics, like the well-adjusted black adolescent, are rarely handled in empirical studies. In this document…

FAA/NASA International Symposium on Advanced Structural Integrity Methods for Airframe Durability and Damage Tolerance, part 2

NASA Technical Reports Server (NTRS)

Harris, Charles E. (Editor)

1994-01-01

The international technical experts in the areas of durability and damage tolerance of metallic airframe structures were assembled to present and discuss recent research findings and the development of advanced design and analysis methods, structural concepts, and advanced materials. The principal focus of the symposium was on the dissemination of new knowledge and the peer-review of progress on the development of advanced methodologies. Papers were presented on the following topics: structural concepts for enhanced durability, damage tolerance, and maintainability; new metallic alloys and processing technology; fatigue crack initiation and small crack effects; fatigue crack growth models; fracture mechanics failure criteria for ductile materials; structural mechanics methodology for residual strength and life prediction; development of flight load spectra for design and testing; and corrosion resistance.

Research in health sciences library and information science: a quantitative analysis.

PubMed Central

Dimitroff, A

1992-01-01

A content analysis of research articles published between 1966 and 1990 in the Bulletin of the Medical Library Association was undertaken. Four specific questions were addressed: What subjects are of interest to health sciences librarians? Who is conducting this research? How do health sciences librarians conduct their research? Do health sciences librarians obtain funding for their research activities? Bibliometric characteristics of the research articles are described and compared to characteristics of research in library and information science as a whole in terms of subject and methodology. General findings were that most research in health sciences librarianship is conducted by librarians affiliated with academic health sciences libraries (51.8%); most deals with an applied (45.7%) or a theoretical (29.2%) topic; survey (41.0%) or observational (20.7%) research methodologies are used; descriptive quantitative analytical techniques are used (83.5%); and over 25% of research is funded. The average number of authors was 1.85, average article length was 7.25 pages, and average number of citations per article was 9.23. These findings are consistent with those reported in the general library and information science literature for the most part, although specific differences do exist in methodological and analytical areas. PMID:1422504

Digital Storytelling: A Novel Methodology for Sexual Health Promotion

ERIC Educational Resources Information Center

Guse, Kylene; Spagat, Andrea; Hill, Amy; Lira, Andrea; Heathcock, Stephen; Gilliam, Melissa

2013-01-01

Digital storytelling draws on the power of narrative for personal and social transformation. This technique has many desirable attributes for sexuality education, including a participatory methodology, provision of a "safe space" to collaboratively address stigmatized topics, and an emphasis on the social and political contexts that…

Structural Equation Modeling of School Violence Data: Methodological Considerations

ERIC Educational Resources Information Center

Mayer, Matthew J.

2004-01-01

Methodological challenges associated with structural equation modeling (SEM) and structured means modeling (SMM) in research on school violence and related topics in the social and behavioral sciences are examined. Problems associated with multiyear implementations of large-scale surveys are discussed. Complex sample designs, part of any…

Optical and digital pattern recognition; Proceedings of the Meeting, Los Angeles, CA, Jan. 13-15, 1987

NASA Technical Reports Server (NTRS)

Liu, Hua-Kuang (Editor); Schenker, Paul (Editor)

1987-01-01

The papers presented in this volume provide an overview of current research in both optical and digital pattern recognition, with a theme of identifying overlapping research problems and methodologies. Topics discussed include image analysis and low-level vision, optical system design, object analysis and recognition, real-time hybrid architectures and algorithms, high-level image understanding, and optical matched filter design. Papers are presented on synthetic estimation filters for a control system; white-light correlator character recognition; optical AI architectures for intelligent sensors; interpreting aerial photographs by segmentation and search; and optical information processing using a new photopolymer.

Dataset for an analysis of communicative aspects of finance.

PubMed

Natalya Zavyalova

2017-04-01

The article describes a step-by-step strategy for designing a universal comprehensive vision of a vast majority of financial research topics. The strategy is focused around the analysis of the retrieval results of the word processing system Serelex which is based on the semantic similarity measure. While designing a research topic, scientists usually employ their individual background. They rely in most cases on their individual assumptions and hypotheses. The strategy, introduced in the article, highlights the method of identifying components of semantic maps which can lead to a better coverage of any scientific topic under analysis. On the example of the research field of finance we show the practical and theoretical value of semantic similarity measurements, i.e., a better coverage of the problems which might be included in the scientific analysis of financial field. At the designing stage of any research scientists are not immune to an insufficient and, thus, erroneous spectrum of problems under analysis. According to the famous maxima of St. Augustine, 'Fallor ergo sum', the researchers' activities are driven along the way from one mistake to another. However, this might not be the case for the 21st century science approach. Our strategy offers an innovative methodology, according to which the number of mistakes at the initial stage of any research may be significantly reduced. The data, obtained, was used in two articles (N. Zavyalova, 2017) [7], (N. Zavyalova, 2015) [8]. The second stage of our experiment was driven towards analyzing the correlation between the language and income level of the respondents. The article contains the information about data processing.

Exposing the Backstage: Critical Reflections on a Longitudinal Qualitative Study of Residents’ Care Networks in Assisted Living

PubMed Central

Kemp, Candace L.; Ball, Mary M.; Morgan, Jennifer Craft; Doyle, Patrick J.; Burgess, Elisabeth O.; Dillard, Joy A.; Barmon, Christina E.; Fitzroy, Andrea F.; Helmly, Victoria E.; Avent, Elizabeth S.; Perkins, Molly M.

2018-01-01

In this article, we analyze the research experiences associated with a longitudinal qualitative study of residents’ care networks in assisted living. Using data from researcher meetings, field notes, and memos, we critically examine our design and decision making and accompanying methodological implications. We focus on one complete wave of data collection involving 28 residents and 114 care network members in four diverse settings followed for 2 years. We identify study features that make our research innovative, but that also represent significant challenges. They include the focus and topic; settings and participants; scope and design complexity; nature, modes, frequency, and duration of data collection; and analytic approach. Each feature has methodological implications, including benefits and challenges pertaining to recruitment, retention, data collection, quality, and management, research team work, researcher roles, ethics, and dissemination. Our analysis demonstrates the value of our approach and of reflecting on and sharing methodological processes for cumulative knowledge building. PMID:27651072

Exposing the Backstage: Critical Reflections on a Longitudinal Qualitative Study of Residents' Care Networks in Assisted Living.

PubMed

Kemp, Candace L; Ball, Mary M; Morgan, Jennifer Craft; Doyle, Patrick J; Burgess, Elisabeth O; Dillard, Joy A; Barmon, Christina E; Fitzroy, Andrea F; Helmly, Victoria E; Avent, Elizabeth S; Perkins, Molly M

2017-07-01

In this article, we analyze the research experiences associated with a longitudinal qualitative study of residents' care networks in assisted living. Using data from researcher meetings, field notes, and memos, we critically examine our design and decision making and accompanying methodological implications. We focus on one complete wave of data collection involving 28 residents and 114 care network members in four diverse settings followed for 2 years. We identify study features that make our research innovative, but that also represent significant challenges. They include the focus and topic; settings and participants; scope and design complexity; nature, modes, frequency, and duration of data collection; and analytic approach. Each feature has methodological implications, including benefits and challenges pertaining to recruitment, retention, data collection, quality, and management, research team work, researcher roles, ethics, and dissemination. Our analysis demonstrates the value of our approach and of reflecting on and sharing methodological processes for cumulative knowledge building.

A Topical Trajectory on Survival: an Analysis of Link-Making in a Sequence of Lessons on Evolution

NASA Astrophysics Data System (ADS)

Rocksén, Miranda; Olander, Clas

2017-04-01

This study explores the concept of link-making in relation to communicative strategies applied in the teaching and studying of biological evolution. The analysis focused on video recordings of 11 lessons on biological evolution conducted in a Swedish 9th grade class of students aged 15 years. It reveals how the teacher and students connected classroom conversations, the frequency of references to conversations in whole-class settings, and the development of a theme focusing on species survival and extinction. Detailed examples from the data illustrate how this theme developed from its initiation during the first lesson, through discussion and clarification, to its wrapping up during the last lesson. They further illustrate how students made sense of what the teacher said and wrote, and how the teacher postponed issues, explained and developed topics, provided opportunities for link-making, organised the class, motivated students, and checked their understanding. The study's methodological approach offers a way of including several time dimensions within research. Based on our findings, we conclude that the excerpts examined here did succeed in building `islands of coherence' in the co-construction of curricular content. Moreover, the topical trajectory in relation to species survival provided opportunities for constructing a `scientific story' in the classroom.

Missing and accounted for: gaps and areas of wealth in the public health review literature

PubMed Central

2011-01-01

Background High-quality review evidence is useful for informing and influencing public health policy and practice decisions. However, certain topic areas lack representation in terms of the quantity and quality of review literature available. The objectives of this paper are to identify the quantity, as well as quality, of review-level evidence available on the effectiveness of public health interventions for public health decision makers. Methods Searches conducted on http://www.health-evidence.ca produced an inventory of public health review literature in 21 topic areas. Gaps and areas of wealth in the review literature, as well as the proportion of reviews rated methodologically strong, moderate, or weak were identified. The top 10 topic areas of interest for registered users and visitors of http://www.health-evidence.ca were extracted from user profile data and Google Analytics. Results Registered users' top three interests included: 1) healthy communities, 2) chronic diseases, and 3) nutrition. The top three preferences for visitors included: 1) chronic diseases, 2) physical activity, and 3) addiction/substance use. All of the topic areas with many (301+) available reviews were of interest to registered users and/or visitors (mental health, physical activity, addiction/substance use, adolescent health, child health, nutrition, adult health, and chronic diseases). Conversely, the majority of registered users and/or visitors did not have preference for topic areas with few (≤ 150) available reviews (food safety and inspection, dental health, environmental health) with the exception of social determinants of health and healthy communities. Across registered users' and visitors' topic areas of preference, 80.2% of the reviews were of well-done methodological quality, with 43.5% of reviews having a strong quality rating and 36.7% a moderate review quality rating. Conclusions In topic areas in which many reviews are available, higher level syntheses are needed to guide policy and practice. For other topic areas with few reviews, it is necessary to determine whether primary study evidence exists, or is needed, so that reviews can be conducted in the future. Considering that less than half of the reviews available on http://www.health-evidence.ca are of strong methodological quality, the quality of the review-level evidence needs to improve across the range of public health topic areas. PMID:21967658

Topics in the Journal of Counseling Psychology, 1963-2015.

PubMed

Oh, JungSu; Stewart, Alan E; Phelps, Rosemary E

2017-11-01

Historical trends in a scientific field should be apparent in the changing content of journal articles over time. Using a topic modeling approach, a statistical method for quantifying the thematic content of text, 70 topics were extracted from the abstracts of 3,603 articles published in the Journal of Counseling Psychology from 1963 to 2015. After examining interpretability of 70 topics derived from the model, 64 meaningful topics and their trends were named. In addition, the authors also classified some of the related topics into 4 categories-counseling process and outcome, multiculturalism, research methodology, and vocational psychology. Counseling process and outcome related topics have decreased recently, while topics relating to multiculturalism and diversity have shown increasing trends. The authors also discussed trends that were observed and tried to account for the changing frequencies of some important research topics within these categories. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

A systematic review of the evidence for topical use of ginger.

PubMed

Ding, Mingshuang; Leach, Matthew J; Bradley, Helen

2013-01-01

The use of ginger as a topical intervention is widely advocated in the popular media. However, there has been no attempt to date to synthesize the evidence for topically administered ginger. To systematically review and synthesize the best available evidence of effectiveness for topical ginger in any condition. CAM on PubMed, CINAHL, Google Scholar, MEDLINE, National Library of Australia, The Cochrane Library, TRIP, pertinent texts, and bibliographies of relevant papers. Data sources were systematically searched for studies investigating the clinical effectiveness of topical ginger, in any form and for any condition, regardless of study design. Studies were limited to those published between 1980 and 2010, and published in English, Mandarin, Cantonese, or Taiwanese. Data were extracted by two authors, independently, using standardized templates. Four studies met the inclusion criteria, including three randomized controlled trials and one non-randomized controlled trial. All studies differed in terms of study population, outcome measures, comparative interventions, and dose and form of ginger used, and thus, were not amenable to meta-analysis. Findings from all trials favored usage of ginger for most outcomes. However, the small sample sizes and inadequate methodological reporting indicate a high risk of bias and the need for caution when interpreting these results. Few studies have investigated the effectiveness of topically administered ginger for any condition. Until the findings of these studies are corroborated by more robust research, and the safety of ginger is adequately established, clinicians should remain cautious about using topical ginger in clinical practice. © 2013 Elsevier Inc. All rights reserved.

USDA Nutrition Evidence Library: methodology used to identify topics and develop systematic review questions for the birth-to-24-mo population.

PubMed

Obbagy, Julie E; Blum-Kemelor, Donna M; Essery, Eve V; Lyon, Joan M G; Spahn, Joanne M

2014-03-01

The USDA's Nutrition Evidence Library (NEL) specializes in conducting food- and nutrition-related systematic reviews that are used to inform federal government decision making. To ensure the utility of NEL systematic reviews, the most relevant topics must be addressed, questions must be clearly focused and appropriate in scope, and review frameworks must reflect the state of the science. Identifying the optimal topics and questions requires input from a variety of stakeholders, including scientists with technical expertise, as well as government policy and program leaders. The objective of this article is to describe the rationale and NEL methodology for identifying topics and developing systematic review questions implemented as part of the "Evaluating the evidence base to support the inclusion of infants and children from birth to 24 months of age in the Dietary Guidelines for Americans--the B-24 Project." This is the first phase of a larger project designed to develop dietary guidance for the birth to 24-mo population in the United States.

A researcher's journey: Exploring a sensitive topic with vulnerable women.

PubMed

Marsh, Christine A; Browne, Jenny; Taylor, Jan; Davis, Deborah

2017-02-01

The conduct of research regardless of the subject or methods employed brings responsibilities and challenges. These are greater when dealing with sensitive topics and vulnerable groups and therefore researchers must navigate a range of complex issues and make choices in relation to practical, ethical and philosophical concerns. While literature dealing with research methodologies and research design may assist to some degree, it cannot provide a clear pathway or template as each research project must respond to a unique set of circumstances. We can however, also learn from sharing our stories and critical reflections on our research processes. The purpose of this article is to highlight the practical and methodological issues arising from researching a sensitive topic with vulnerable women experiencing an Assumption of Care. Research involving topics that are deeply personal and private combined with a vulnerable population can be complex and challenging for the researcher. Although some issues were anticipated from the literature, others encountered in this study were unexpected. Special considerations and prerequisites were necessary to build mutual trust and share power with women who had experienced an Assumption of Care at birth. Narrative Inquiry was a good methodological fit for this study as it privileged the voices of women and insisted that their experiences be considered within the context of their lives. Although Narrative Inquiry is a suitable choice for researching sensitive topics with vulnerable women specific considerations are still required to ensure the benefits of this research for both participants and researchers. Family and Community Service (FACS) have now replaced the formerly known Department of Community Services (DoCS) and in consideration of the timing of this study this article uses the terminology as DoCS. Copyright © 2016 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

Applying Sparse Machine Learning Methods to Twitter: Analysis of the 2012 Change in Pap Smear Guidelines. A Sequential Mixed-Methods Study.

PubMed

Lyles, Courtney Rees; Godbehere, Andrew; Le, Gem; El Ghaoui, Laurent; Sarkar, Urmimala

2016-06-10

It is difficult to synthesize the vast amount of textual data available from social media websites. Capturing real-world discussions via social media could provide insights into individuals' opinions and the decision-making process. We conducted a sequential mixed methods study to determine the utility of sparse machine learning techniques in summarizing Twitter dialogues. We chose a narrowly defined topic for this approach: cervical cancer discussions over a 6-month time period surrounding a change in Pap smear screening guidelines. We applied statistical methodologies, known as sparse machine learning algorithms, to summarize Twitter messages about cervical cancer before and after the 2012 change in Pap smear screening guidelines by the US Preventive Services Task Force (USPSTF). All messages containing the search terms "cervical cancer," "Pap smear," and "Pap test" were analyzed during: (1) January 1-March 13, 2012, and (2) March 14-June 30, 2012. Topic modeling was used to discern the most common topics from each time period, and determine the singular value criterion for each topic. The results were then qualitatively coded from top 10 relevant topics to determine the efficiency of clustering method in grouping distinct ideas, and how the discussion differed before vs. after the change in guidelines . This machine learning method was effective in grouping the relevant discussion topics about cervical cancer during the respective time periods (~20% overall irrelevant content in both time periods). Qualitative analysis determined that a significant portion of the top discussion topics in the second time period directly reflected the USPSTF guideline change (eg, "New Screening Guidelines for Cervical Cancer"), and many topics in both time periods were addressing basic screening promotion and education (eg, "It is Cervical Cancer Awareness Month! Click the link to see where you can receive a free or low cost Pap test.") It was demonstrated that machine learning tools can be useful in cervical cancer prevention and screening discussions on Twitter. This method allowed us to prove that there is publicly available significant information about cervical cancer screening on social media sites. Moreover, we observed a direct impact of the guideline change within the Twitter messages.

Understanding Social Media’s Take on Climate Change through Large-Scale Analysis of Targeted Opinions and Emotions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pathak, Neetu; Henry, Michael J.; Volkova, Svitlana

Social media is a powerful data source for researchers interested in understanding population-level behavior, having been successfully leveraged in a number of different application areas including flu and illness prediction models, detecting civil unrest, and measuring public sentiment towards a given topic of interest within the public discourse. In this work, we present a study of a large collection of Twitter data centered on the social conversation around global cli- mate change during the UN Climate Change Conference, held in Paris, France during December 2015 (COP21). We first developed a mechanism for distinguishing between personal and non-personal accounts. We thenmore » analyzed demographics and emotion and opinion dynamics over time and location in order to understand how the different user types converse around meaningful topics on social media. This methodology offers an in-depth insight into the behavior and opinions around a topic where multiple distinct narratives are present, and lays the groundwork for future work in studying narratives in social media.« less

Measurement, analysis and prediction of topical UV filter bioavailability.

PubMed

Roussel, L; Gilbert, E; Salmon, D; Serre, C; Gabard, B; Haftek, M; Maibach, H I; Pirot, F

2015-01-30

The aim of the present study was to objectively quantify and predict bioavailability of three sunscreen agents (i.e., benzophenone-3, 2-ethylhexylsalicylate, and 2 ethylhexyl-4-methoxycinnamate) in epidermis treated by petrolatum and emulsion-based formulations for 7 and 30min on four human volunteers. Profiles of sunscreen agents through stratum corneum (SC), derived from the assessment of chemical amounts in SC layers collected by successive adhesive tape-stripping, were successfully fitted to Fick's second law of diffusion. Therefore, permeability coefficients of sunscreen agents were found lower with petrolatum than with emulsion based formulations confirming the crucial role of vehicle in topical delivery. Furthermore, the robustness of that methodology was confirmed by the linear relationship between the chemical absorption measured after 30min and that predicted from the 7-min exposure experiment. Interestingly, in this dermatopharmacokinetic method, the deconvolution of permeability coefficients in their respective partition coefficients and absorption constants allowed a better understanding of vehicle effects upon topical bioavailability mechanisms and bioequivalence of skin products. Copyright © 2014 Elsevier B.V. All rights reserved.

Clinical practice guidelines for fertility preservation in young women undergoing gonadotoxic treatment: an overview and critical appraisal of methodological quality and content.

PubMed

Baysal, Özlem; Hamilton, Jozefien A M; Hamilton, Carl J C M; Braat, Didi D M; Beerendonk, Catharina C M; Nelen, Willianne L D M

2018-04-13

What is the methodological quality and content of internationally available clinical practice guidelines (CPGs) on fertility preservation (FP) care in adult women? Internationally available CPGs on FP care in adult women were identified after conducting an extensive literature search and consulting (inter)national key experts. The methodological quality of the CPGs was appraised by an (inter)national panel of experts using the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument. The content of the best CPGs, scoring ≥60% for the domain 'Rigour of development' of the AGREE II instrument, was extracted and categorized according to their topic. Thirty of the 1808 documents found were included. After consulting (inter)national key experts, 30 CPGs were included, six of which scored ≥60% for their 'Rigour of development'. The number of FP-related topics discussed by these six CPGs ranged from 4 to 12. The number of recommendations provided by the CPGs on these topics varied. The number of topics to which ≥5 recommendations were dedicated ranged from 0 to 4 between CPGs. CPGs on the subject of FP care are available, but there is room for improvement in quality and content. Although written for use in daily practice, the CPGs can also be used to develop quality indicators to monitor the quality of current FP care or to evaluate future improvement initiatives. Copyright © 2018 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Strengthening the perception-assessment tools for dengue prevention: a cross-sectional survey in a temperate region (Madeira, Portugal)

PubMed Central

2014-01-01

Background Community participation is mandatory in the prevention of Dengue outbreaks. Taking public views into account is crucial to guide more effective planning and quicker community participation in preventing campaigns. This study aims to assess community perceptions of Madeira population in order to explore their involvement in the A. aegypti’s control and reinforce health-educational planning. Due to the lack of accurate methodologies for measuring perception, a new tool to assess the community’s perceptions was built. Methods A cross-sectional survey was performed in the Island’s aegypti-infested area, exploring residents’ perceptions regarding most critical community behaviour: aegypti-source reduction and their domestic aegypti-breeding sites. A novel tool defining five essential topics which underlie the source reduction’s awareness and accession was built, herein called Essential-Perception (EP) analysis. Results Of 1276 individuals, 1182 completed the questionnaire (92 · 6%). EP-Score analysis revealed that community’s perceptions were scarce, inconsistent and possibly incorrect. Most of the population (99 · 6%) did not completely understood the five essential topics explored. An average of 54 · 2% of residents only partially understood each essential topic, revealing inconsistencies in their understanding. Each resident apparently believed in an average of four false assumptions/myths. Significant association (p<0.001) was found between both the EP-Score level and the domestic presence of breeding sites, supporting the validity of this EP-analysis. Aedes aegypti’s breeding sites, consisting of décor/leisure containers, presented an atypical pattern of infestation comparing with dengue prone regions. Conclusions The studied population was not prepared for being fully engaged in dengue prevention. Evidences suggest that EP-methodology was efficient and accurate in assessing the community perception and its compliance to practices. Moreover, it suggested a list of myths that could persist in the community. This is the first study reporting an aegypti-entomological pattern and community’s perception in a developed dengue-prone region. Tailored messages considering findings of this study are recommended to be used in future campaigns in order to more effectively impact the community perception and behaviour. PMID:24428823

Strengthening the perception-assessment tools for dengue prevention: a cross-sectional survey in a temperate region (Madeira, Portugal).

PubMed

Nazareth, Teresa; Teodósio, Rosa; Porto, Graça; Gonçalves, Luzia; Seixas, Gonçalo; Silva, Ana Clara; Sousa, Carla Alexandra

2014-01-15

Community participation is mandatory in the prevention of Dengue outbreaks. Taking public views into account is crucial to guide more effective planning and quicker community participation in preventing campaigns. This study aims to assess community perceptions of Madeira population in order to explore their involvement in the A. aegypti's control and reinforce health-educational planning. Due to the lack of accurate methodologies for measuring perception, a new tool to assess the community's perceptions was built. A cross-sectional survey was performed in the Island's aegypti-infested area, exploring residents' perceptions regarding most critical community behaviour: aegypti-source reduction and their domestic aegypti-breeding sites. A novel tool defining five essential topics which underlie the source reduction's awareness and accession was built, herein called Essential-Perception (EP) analysis. Of 1276 individuals, 1182 completed the questionnaire (92 · 6%). EP-Score analysis revealed that community's perceptions were scarce, inconsistent and possibly incorrect. Most of the population (99 · 6%) did not completely understood the five essential topics explored. An average of 54 · 2% of residents only partially understood each essential topic, revealing inconsistencies in their understanding. Each resident apparently believed in an average of four false assumptions/myths. Significant association (p<0.001) was found between both the EP-Score level and the domestic presence of breeding sites, supporting the validity of this EP-analysis. Aedes aegypti's breeding sites, consisting of décor/leisure containers, presented an atypical pattern of infestation comparing with dengue prone regions. The studied population was not prepared for being fully engaged in dengue prevention. Evidences suggest that EP-methodology was efficient and accurate in assessing the community perception and its compliance to practices. Moreover, it suggested a list of myths that could persist in the community. This is the first study reporting an aegypti-entomological pattern and community's perception in a developed dengue-prone region. Tailored messages considering findings of this study are recommended to be used in future campaigns in order to more effectively impact the community perception and behaviour.

How Discourses of Biology Textbooks Work to Constitute Subjectivity: From the Ethical to the Colonial

NASA Astrophysics Data System (ADS)

Bazzul, Jesse

This thesis examines how discourses of biology textbooks can work to constitute various kinds of subjectivities. Using a Foucauldian archaeological approach to discourse analysis I examine how four Ontario secondary school biology textbooks discursively delimit what can be thought and acted upon, and in the process work to partially constitute students/teachers as sex/gendered; neocolonial; neoliberal (and a subject of work), and ethical subjects and subjectivities. This thesis engages the topic of how discourse can constitute subjectivity in science in three basic ways: First, on a theoretical level, in terms of working out an understanding of subject constitution/interpellation that would also be useful when engaging with other sociopolitical and ethical questions in science education. Secondly, in terms of an empirically based critical discourse analysis that examines how various statements within these four textbooks could set limits on what is possible for students to think and act upon in relation to themselves, science, and the world. Thirdly, this thesis represents a narrative of scholarly development that moves from an engagement of my personal experiences in science education and current science education literature towards the general politico-philosophical topic of subjectivity and biopolitics. This thesis begins with a discussion of my experiences as a science teacher, a review of relevant science education literature, and considerations of subjectivity that relate specifically ii to the specific methodological approach I employ when examining these textbooks. After this I present five chapters, each of which can be thought of as a somewhat separate analysis concerning how the discourses of these textbooks can work to constitute specific subjectivities (each involving different theoretical/methodological considerations). I conclude with a reflection/synthesis chapter and a call to see science education as a site for biopolitical struggle.

Dealing With Major Life Events and Transitions: A Systematic Literature Review on and Occupational Analysis of Spirituality.

PubMed

Maley, Christine M; Pagana, Nicole K; Velenger, Christa A; Humbert, Tamera Keiter

2016-01-01

This systematic literature review analyzed the construct of spirituality as perceived by people who have experienced or are experiencing a major life event or transition. The researchers investigated studies that used narrative analysis or a phenomenological methodology related to the topic. Thematic analysis resulted in three major themes: (1) avenues to and through spirituality, (2) the experience of spirituality, and (3) the meaning of spirituality. The results provide insights into the intersection of spirituality, meaning, and occupational engagement as understood by people experiencing a major life event or transition and suggest further research that addresses spirituality in occupational therapy and interdisciplinary intervention. Copyright © 2016 by the American Occupational Therapy Association, Inc.

The 1993 Gordon Research Conference on Chronobiology

NASA Technical Reports Server (NTRS)

Schwartz, William J.

1993-01-01

The study of biological timekeeping is now at a particularly fertile stage, encompassing multiple levels of biological organization, recruiting a wide array of disciplines and methodologies and uniting a host of investigators. This report summarizes a research conference on Chronobiology. Some of the topics focused on transcriptional and translational mechanisms of circadian rhythmicity, with discussions of putative 'clock genes' in cyanobacteria, algae, fungi, fruitflies, and hamsters. Cellular analysis, with emphasis on photoreceptors in frogs, neurons in molluscs, and testis in moths was addressed. New methods for investigating the circadian clock in the suprachiasmatic nucleus were introduced.

Human error and the search for blame

NASA Technical Reports Server (NTRS)

Denning, Peter J.

1989-01-01

Human error is a frequent topic in discussions about risks in using computer systems. A rational analysis of human error leads through the consideration of mistakes to standards that designers use to avoid mistakes that lead to known breakdowns. The irrational side, however, is more interesting. It conditions people to think that breakdowns are inherently wrong and that there is ultimately someone who is responsible. This leads to a search for someone to blame which diverts attention from: learning from the mistakes; seeing the limitations of current engineering methodology; and improving the discourse of design.

Effects of Task Relevance Instructions and Topic Beliefs on Reading Processes and Memory

ERIC Educational Resources Information Center

Bohn-Gettler, Catherine M.; McCrudden, Matthew T.

2018-01-01

This study investigated the effects of task relevance instructions and topic beliefs on reading processes and memory for belief-related text. Undergraduates received task instructions (focus on arguments for vs. against) before reading a dual-position text. In Experiment 1 (n = 88), a reading time methodology showed no differences in reading time…

Increasing Understanding of Public Problems and Policies. A Group Study of Four Topics in the Field of Extension Education.

ERIC Educational Resources Information Center

Farm Foundation, Chicago, IL.

The publication contains thirteen reports from the Twentieth National Agricultural Policy Conference held September 22-25, 1970, at Pokagon State Park, Angola, Indiana. The conference was designed to assist extension workers by broadening their perspective, understanding, and handling of the methodology of public affairs education. Four topics in…

Multimedia Learning System and Its Effect on Self-Efficacy in Database Modeling and Design: An Exploratory Study

ERIC Educational Resources Information Center

Cheung, Waiman; Li, Eldon Y.; Yee, Lester W.

2003-01-01

Metadatabase modeling and design integrate process modeling and data modeling methodologies. Both are core topics in the information technology (IT) curriculum. Learning these topics has been an important pedagogical issue to the core studies for management information systems (MIS) and computer science (CSc) students. Unfortunately, the learning…

Meta-analyses on intra-aortic balloon pump in cardiogenic shock complicating acute myocardial infarction may provide biased results.

PubMed

Acconcia, M C; Caretta, Q; Romeo, F; Borzi, M; Perrone, M A; Sergi, D; Chiarotti, F; Calabrese, C M; Sili Scavalli, A; Gaudio, C

2018-04-01

Intra-aortic balloon pump (IABP) is the device most commonly investigated in patients with cardiogenic shock (CS) complicating acute myocardial infarction (AMI). Recently meta-analyses on this topic showed opposite results: some complied with the actual guideline recommendations, while others did not, due to the presence of bias. We investigated the reasons for the discrepancy among meta-analyses and strategies employed to avoid the potential source of bias. Scientific databases were searched for meta-analyses of IABP support in AMI complicated by CS. The presence of clinical diversity, methodological diversity and statistical heterogeneity were analyzed. When we found clinical or methodological diversity, we reanalyzed the data by comparing the patients selected for homogeneous groups. When the fixed effect model was employed despite the presence of statistical heterogeneity, the meta-analysis was repeated adopting the random effect model, with the same estimator used in the original meta-analysis. Twelve meta-analysis were selected. Six meta-analyses of randomized controlled trials (RCTs) were inconclusive because underpowered to detect the IABP effect. Five included RCTs and observational studies (Obs) and one only Obs. Some meta-analyses on RCTs and Obs had biased results due to presence of clinical and/or methodological diversity. The reanalysis of data reallocated for homogeneous groups was no more in contrast with guidelines recommendations. Meta-analyses performed without controlling for clinical and/or methodological diversity, represent a confounding message against a good clinical practice. The reanalysis of data demonstrates the validity of the current guidelines recommendations in addressing clinical decision making in providing IABP support in AMI complicated by CS.

Integrated teaching program using case-based learning

PubMed Central

Bhardwaj, Pankaj; Bhardwaj, Nikha; Mahdi, Farzana; Srivastava, J P; Gupta, Uma

2015-01-01

Background: At present, in a medical school, students are taught in different departments, subject-wise, without integration to interrelate or unify subjects and these results in compartmentalization of medical education, with no stress on case-based learning. Therefore, an effort was made to develop and adopt integrated teaching in order to have a better contextual knowledge among students. Methodology and Implementation: After the faculty orientation training, four “topic committees” with faculty members from different departments were constituted which decided and agreed on the content material to be taught, different methodologies to be used, along with the logical sequencing of the same for the purpose of implementation. Different teaching methodologies used, during the program, were didactic lectures, case stimulated sessions, clinical visits, laboratory work, and small group student's seminar. Results: After the implementation of program, the comparison between two batches as well as between topics taught with integrated learning program versus traditional method showed that students performed better in the topics, taught with integrated approach. Students rated “clinical visits” as very good methodology, followed by “case stimulated interactive sessions.” Students believed that they felt more actively involved, and their queries are better addressed with such interactive sessions. Conclusion: There is a very good perception of students toward integrated teaching. Students performed better if they are taught using this technique. Although majority of faculty found integrated teaching, as useful method of teaching, nevertheless extra work burden and interdepartmental coordination remained a challenging task. PMID:26380204

Slow crack growth test method for polyethylene gas pipes. Volume 1. Topical report, December 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leis, B.; Ahmad, J.; Forte, T.

1992-12-01

In spite of the excellent performance record of polyethylene (PE) pipes used for gas distribution, a small number of leaks occur in distribution systems each year because of slow growth of cracks through pipe walls. The Slow Crack Growth Test (SCG) has been developed as a key element in a methodology for the assessment of the performance of polyethylene gas distribution systems to resist such leaks. This tropical report describes work conducted in the first part of the research directed at the initial development of the SCG test, including a critical evaluation of the applicability of the SCG test asmore » an element in PE gas pipe system performance methodology. Results of extensive experiments and analysis are reported. The results show that the SCG test should be very useful in performance assessment.« less

National Institute for Petroleum and Energy Research quarterly technical report for April 1--June 30, 1993. Volume 1, Fuels research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Progress reports are presented for the following fuels researches: Development of analytical methodology for analysis of heave crudes; and thermochemistry and thermophysical properties of organic nitrogen and diheteroatom-containing compounds. Some of the accomplishments are: Topical reports summarizing GC/MS methodology for determination of amines in petroleum and catalytic cracking behavior of compound type in Wilmington 650{degrees} F+ resid were completed; density measurements between 320 K and 550 K were completed for 8-methylquinoline; high-temperature heat-capacities and critical temperature (near 800 K) for 8-methylquinoline were determined; vapor-pressure measurements were completed for 2,6-dimethylpyridine; and a series of enthalpy-of-combustion measurement was completed for 1,10-phenanthroline, phenazine,more » 2-methylquinoline, and 8-methylquinoline.« less

Methodological quality and implications for practice of systematic Cochrane reviews in pediatric oral health: a critical assessment

PubMed Central

2014-01-01

Background To ensure evidence-based decision-making in pediatric oral health, Cochrane systematic reviews that address topics pertinent to this field are necessary. We aimed to identify all systematic reviews of paediatric dentistry and oral health by the Cochrane Oral Health Group (COHG), summarize their characteristics and assess their methodological quality. Our second objective was to assess implications for practice in the review conclusions and provide an overview of clinical implications about the usefulness of paediatric oral health interventions in practice. Methods We conducted a methodological survey including all paediatric dentistry reviews from the COHG. We extracted data on characteristics of included reviews, then assessed the methodological quality using a validated 11-item quality assessment tool (AMSTAR). Finally, we coded each review to indicate whether its authors concluded that an intervention should be implemented in practice, was not supported or was refuted by the evidence, or should be used only in research (inconclusive evidence). Results We selected 37 reviews; most concerned the prevention of caries. The methodological quality was high, except for the assessment of reporting bias. In 7 reviews (19%), the research showed that benefits outweighed harms; in 1, the experimental intervention was found ineffective; and in 29 (78%), evidence was insufficient to assess benefits and harms. In the 7 reviews, topical fluoride treatments (with toothpaste, gel or varnish) were found effective for permanent and deciduous teeth in children and adolescents, and sealants for occlusal tooth surfaces of permanent molars. Conclusions Cochrane reviews of paediatric dentistry were of high quality. They provided strong evidence that topical fluoride treatments and sealants are effective for children and adolescents and thus should be implemented in practice. However, a substantial number of reviews yielded inconclusive evidence. PMID:24716532

[Evaluation of medication risk in pregnant women: methodology of evaluation and risk management].

PubMed

Eléfant, E; Sainte-Croix, A

1997-01-01

This round table discussion was devoted to the description of the tools currently available for the evaluation of drug risks and management during pregnancy. Five topics were submitted for discussion: pre-clinical data, methodological tools, benefit/risk ratio before prescription, teratogenic or fetal risk evaluation, legal comments.

Science, Technology, and Society: A Perspective on the Enhancement of Scientific Education

ERIC Educational Resources Information Center

Courville, Keith

2009-01-01

(Purpose) This literature review discusses the history and application of science, technology, and society (STS) teaching methodologies. (Findings) Topics addressed in this paper include: (1) developmental history of STS; (2) fundamental beliefs of STS practitioners; (3) STS methodology in the classroom; (4) Difficulty in implementing STS; (5) STS…

Economic Evaluation of Adolescent Addiction Programs: Methodological Challenges and Recommendations

PubMed Central

Homer, Jenny F.; Drummond, Michael F.; French, Michael T.

2008-01-01

This paper identifies and describes several methodological challenges encountered in economic evaluations of substance abuse interventions for adolescents. Topics include study design, the choice of perspective, the estimation of costs and outcomes, and the generalizability of results. Recommendations are offered for confronting these challenges using examples from adolescent addiction research. PMID:19027640

Decoding the Disciplines: An Approach to Scientific Thinking

ERIC Educational Resources Information Center

Pinnow, Eleni

2016-01-01

The Decoding the Disciplines methodology aims to teach students to think like experts in discipline-specific tasks. The central aspect of the methodology is to identify a bottleneck in the course content: a particular topic that a substantial number of students struggle to master. The current study compared the efficacy of standard lecture and…

A case for the use of Q-methodology in disability research: lessons learned from a training workshop.

PubMed

McKenzie, Judith; Braswell, Bob; Jelsma, Jennifer; Naidoo, Nirmala

2011-01-01

Q-methodology was developed to analyse subjective responses to a range of items dealing with specific topics. This article describes the use of Q-methodology and presents the results of a Q-study on perspectives on disability carried out in a training workshop as evidence for its usefulness in disability research. A Q-sort was administered in the context of a training workshop on Q-method. The Q-sort consisted of statements related to the topic of disability. The responses were analysed using specifically developed software to identify factors that represent patterns of responses. Twenty-two of the 23 respondents loaded on four factors. These factors appeared to represent different paradigms relating to the social, medical and disability rights models of disability. The fourth factor appeared to be that of a family perspective. These are all models evident in the disability research literature and provide evidence for the validity of Q-method in disability research. Based on this opportunistic study, it would appear that Q-methodology is a useful tool for identifying different view points related to disability.

Evaluation of inositol phosphates in urine after topical administration of myo-inositol hexaphosphate to female Wistar rats.

PubMed

Grases, F; Costa-Bauzá, A; Berga, F; Rodríguez, A; Gomila, R M; Martorell, G; Martínez-Cignoni, M R

2018-01-01

Previous studies demonstrated a remarkable increase of urinary InsP 6 by topical administration. However, the methodology used for InsP 6 analysis was not specific. The aim of this paper is to measure urinary inositol phosphates InsPs using more advanced methodologies and to compare the results with those obtained by the non-specific method. We fed 12 female rats with a diet without InsP 6 for 16days. Then, we administered a topical InsP 6 gel at high doses for 7days (50mgInsP 6 /day) or at low doses for 28days (20mgInsP 6 /day). We measured urine levels InsPs using a nonspecific method (based on the ability of InsPs to complex Al 3+ ) and levels of InsP 6 by a specific method (using polyacrylamide gel electrophoresis). Identification of different InsPs was performed by MS. At baseline, after dietary deprivation of InsP 6 , rats only excreted InsP 2 in their urine, and there was no detectable InsP 6 or other InsPs. Rats given the high dose treatment for 7days had abundant urinary InsP 6 , but also had other InsPs in their urine; cessation of InsP 6 administration led to decreased levels of urinary InsPs. Rats given the low dose treatment for 28days had increasing levels of urinary InsPs over time. The maximum urinary InsP 6 was at 21days, after which InsPs excretion decreased. We conclude that the skin can absorb InsP 6 from a topical gel, and that InsP 6 is excreted in the urine, along with other InsPs (InsP 5 , InsP 4 , InsP 3 , and InsP 2 ). Copyright © 2017 Elsevier Inc. All rights reserved.

Sexuality Research in Iran: A Focus on Methodological and Ethical Considerations.

PubMed

Rahmani, Azam; Merghati-Khoei, Effat; Moghaddam-Banaem, Lida; Zarei, Fatemeh; Montazeri, Ali; Hajizadeh, Ebrahim

2015-07-01

Research on sensitive topics, such as sexuality, could raise technical, methodological, ethical, political, and legal challenges. The aim of this paper was to draw the methodological challenges which the authors confronted during sexuality research with young population in the Iranian culture. This study was an exploratory mixed method one conducted in 2013-14. We interviewed 63 young women aged 18-34 yr in qualitative phase and 265 young women in quantitative phase in (university and non-university) dormitories and in an Adolescent Friendly Center. Data were collected using focus group discussions and individual interviews in the qualitative phase. We employed conventional content analysis to analyze the data. To enhance the rigor of the data, multiple data collection methods, maximum variation sampling, and peer checks were applied. Five main themes emerged from the data: interaction with opposite sex, sexual risk, sexual protective, sex education, and sexual vulnerability. Challenges while conducting sex research have been discussed. These challenges included assumption of promiscuity, language of silence and privacy concerns, and sex segregation policy. We described the strategies applied in our study and the rationales for each strategy. Strategies applied in the present study can be employed in contexts with the similar methodological and moral concerns.

GLOBECOM '85 - Global Telecommunications Conference, New Orleans, LA, December 2-5, 1985, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

Various papers on global telecommunications are presented. The general topics addressed include: multiservice integration with optical fibers, multicompany owned telecommunication networks, softworks quality and reliability, advanced on-board processing, impact of new services and systems on operations and maintenance, analytical studies of protocols for data communication networks, topics in packet radio networking, CCITT No. 7 to support new services, document processing and communication, antenna technology and system aspects in satellite communications. Also considered are: communication systems modelling methodology, experimental integrated local area voice/data nets, spread spectrum communications, motion video at the DS-0 rate, optical and data communications, intelligent work stations, switch performance analysis, novel radio communication systems, wireless local networks, ISDN services, LAN communication protocols, user-system interface, radio propagation and performance, mobile satellite system, software for computer networks, VLSI for ISDN terminals, quality management, man-machine interfaces in switching, and local area network performance.

Advances in Risk Analysis with Big Data.

PubMed

Choi, Tsan-Ming; Lambert, James H

2017-08-01

With cloud computing, Internet-of-things, wireless sensors, social media, fast storage and retrieval, etc., organizations and enterprises have access to unprecedented amounts and varieties of data. Current risk analysis methodology and applications are experiencing related advances and breakthroughs. For example, highway operations data are readily available, and making use of them reduces risks of traffic crashes and travel delays. Massive data of financial and enterprise systems support decision making under risk by individuals, industries, regulators, etc. In this introductory article, we first discuss the meaning of big data for risk analysis. We then examine recent advances in risk analysis with big data in several topic areas. For each area, we identify and introduce the relevant articles that are featured in the special issue. We conclude with a discussion on future research opportunities. © 2017 Society for Risk Analysis.

[Bibliometric analysis of publications by the Mexican Social Security Institute staff].

PubMed

Valdez-Martínez, E; Garduño-Espinosa, J; Gómez-Delgado, A; Dante Amato-Martínez, J; Morales-Mori, L; Blanco-Favela, F; Muñoz-Hernández, O

2000-01-01

To describe and analyze the general characteristics and methodology of indexed publications by the health staff of the Mexican Social Security Institute in 1997. Original articles were evaluated. The primary sources included Index Medicus, Current Contents and the Mexican National Council of Science and Technology (CONACYT) index. The following information was gathered for each article: affiliation and chief activity of the first author; impact factor of the journal; research type; field of study; topic of study, and methodological conduction. This latter point included congruence between design and objective, reproducibility of methods, applicability of the analysis, and pertinence of the conclusions. A total of 300 original articles was published of which 212 (71%) were available for the present study: full-time investigators (FTI) generated 109 articles and investigators with clinical activities (CAI) wrote 103 articles. The median impact factor of the journals in which FTI published was 1.337 (0.341 to 37.297) and for CAI publications, 0.707 (0.400 to 4.237). Biomedical research predominated in the first group (41%) and clinical investigation in the second (66%). Statistically significant differences were identified for the methodological conduction between groups of investigators. Descriptive studies and publications in journals without impact factor predominated. The FTI group had the highest bibliographic production of original articles in indexed journals with an impact factor.

Advances in Educational and Psychological Testing: Theory and Applications. Evaluation in Education and Human Services Series.

ERIC Educational Resources Information Center

Hambleton, Ronald K., Ed.; Zaal, Jac N., Ed.

The 14 chapters of this book focus on the technical advances, advances in applied settings, and emerging topics in the testing field. Part 1 discusses methodological advances, Part 2 considers developments in applied settings, and Part 3 reviews emerging topics in the field of testing. Part 1 papers include: (1) "Advances in…

The Comprehensive Longitudinal Evaluation of the Milwaukee Parental Choice Program: Summary of Final Reports. SCDP Milwaukee Evaluation Report #36

ERIC Educational Resources Information Center

Wolf, Patrick J.

2012-01-01

This report contains a summary of the findings from the various topical reports that comprise the author's comprehensive longitudinal study. As a summary, it does not include extensive details regarding the study samples and scientific methodologies employed in those topical studies. The research revealed a pattern of school choice results that…

Funding for the Future: Strategic Research in Further Education. A Report for FEDA.

ERIC Educational Resources Information Center

Bellfield, C. R.; Bullock, A. D.; Rikowski, G.; Thomas, H. R.

A research study focused on the funding method for further education (FE) in Britain. From a theoretical study of the stimuli built into the new funding methodology, four topics of interest were selected for further investigation. To clarify the arguments, these topics were cast as a series of hypotheses that could then be tested using both…

Review of Doctoral Research on Second Language Teaching and Learning in Spain (2008-2010)

ERIC Educational Resources Information Center

Serrano, Raquel; Miralpeix, Imma

2013-01-01

This paper reviews a selection of doctoral theses on language learning and teaching completed in Spain between 2008 and 2010. A total of 16 theses have been identified as representative--in terms of the topics under investigation and the methodology employed--of the doctoral research undertaken in Spain. Current topics include the development of…

Relationship between Active Learning Methodologies and Community College Students' STEM Course Grades

ERIC Educational Resources Information Center

Lesk, Cherish Christina Clark

2017-01-01

Active learning methodologies (ALM) are associated with student success, but little research on this topic has been pursued at the community college level. At a local community college, students in science, technology, engineering, and math (STEM) courses exhibited lower than average grades. The purpose of this study was to examine whether the use…

Paradigms Lost and Pragmatism Regained: Methodological Implications of Combining Qualitative and Quantitative Methods

ERIC Educational Resources Information Center

Morgan, David L.

2007-01-01

This article examines several methodological issues associated with combining qualitative and quantitative methods by comparing the increasing interest in this topic with the earlier renewal of interest in qualitative research during the 1980s. The first section argues for the value of Kuhn's concept of paradigm shifts as a tool for examining…

Integration of PBL Methodologies into Online Learning Courses and Programs

ERIC Educational Resources Information Center

van Oostveen, Roland; Childs, Elizabeth; Flynn, Kathleen; Clarkson, Jessica

2014-01-01

Problem-based learning (PBL) challenges traditional views of teaching and learning as the learner determines, to a large extent with support from a skilled facilitator, what topics will be explored, to what depth and which processes will be used. This paper presents the implementation of problem-based learning methodologies in an online Bachelor's…

Distributing Leadership in English Sixth Form Colleges: Liberation or Another Form of Managerial Control?

ERIC Educational Resources Information Center

Stoten, David William

2015-01-01

Purpose: The purpose of this paper is to explore the distribution of leadership practices in Sixth Form Colleges (SFCs). This is an area where very little research has been undertaken and the intention was to investigate the topic from a critical perspective using social constructionist methodology. Design/methodology/approach: The research…

Assessment of dermatopharmacokinetic approach in the bioequivalence determination of topical tretinoin gel products.

PubMed

Pershing, Lynn K; Nelson, Joel L; Corlett, Judy L; Shrivastava, Surendra P; Hare, Don B; Shah, Vinod P

2003-05-01

A new dermatopharmacokinetic (DPK) approach has been proposed for bioequivalence determination of topical drug products by comparing the drug content kinetics in stratum corneum. We sought to establish any correlation between clinical safety/efficacy and DPK approach in bioequivalence determination of tretinoin gel 0.025%. Tretinoin and isotretinoin were quantified in human volar forearm stratum corneum as a function of time with 3 tretinoin gel 0.025% products in 49 patients. Stratum corneum layers were harvested using multiple adhesive disks, which were subsequently extracted and quantified for both isomers by high-performance liquid chromatography. Products with similar composition and therapeutic equivalence were found bioequivalent, and products with different composition and clinical profiles were found bioinequivalent by DPK methodology. There is a direct correlation between DPK parameters in healthy patients and clinical safety/efficacy of tretinoin gel products in patients with acne. Data support the use of DPK parameters and methodology in the bioequivalence assessment of topical tretinoin gel products.

The Italian Consensus Conference on Pain in Neurorehabilitation: rationale and methodology

PubMed Central

Tamburin, Stefano; Paolucci, Stefano; Magrinelli, Francesca; Musicco, Massimo; Sandrini, Giorgio

2016-01-01

Pain is very common in the neurorehabilitation setting, where it may not only represent a target for treatment but can also negatively influence rehabilitation procedures directly or through the side effects of painkillers. To date, there are neither guidelines nor consensus on how to assess and treat pain in neurorehabilitation. Because of the very scanty pieces of evidence on this topic, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) was promoted under the auspices of different scientific societies. This article illustrates the rationale, methodology, and topics of the ICCPN. The recommendations of the ICCPN will offer some information on how to deal with pain in neurorehabilitation and may represent the starting point for further studies. PMID:27313474

Fuzzy logic based sensor performance evaluation of vehicle mounted metal detector systems

NASA Astrophysics Data System (ADS)

Abeynayake, Canicious; Tran, Minh D.

2015-05-01

Vehicle Mounted Metal Detector (VMMD) systems are widely used for detection of threat objects in humanitarian demining and military route clearance scenarios. Due to the diverse nature of such operational conditions, operational use of VMMD without a proper understanding of its capability boundaries may lead to heavy causalities. Multi-criteria fitness evaluations are crucial for determining capability boundaries of any sensor-based demining equipment. Evaluation of sensor based military equipment is a multi-disciplinary topic combining the efforts of researchers, operators, managers and commanders having different professional backgrounds and knowledge profiles. Information acquired through field tests usually involves uncertainty, vagueness and imprecision due to variations in test and evaluation conditions during a single test or series of tests. This report presents a fuzzy logic based methodology for experimental data analysis and performance evaluation of VMMD. This data evaluation methodology has been developed to evaluate sensor performance by consolidating expert knowledge with experimental data. A case study is presented by implementing the proposed data analysis framework in a VMMD evaluation scenario. The results of this analysis confirm accuracy, practicability and reliability of the fuzzy logic based sensor performance evaluation framework.

Functional Magnetic Resonance Imaging of the Domestic Dog: Research, Methodology, and Conceptual Issues

PubMed Central

Thompkins, Andie M.; Deshpande, Gopikrishna; Waggoner, Paul; Katz, Jeffrey S.

2017-01-01

Neuroimaging of the domestic dog is a rapidly expanding research topic in terms of the cognitive domains being investigated. Because dogs have shared both a physical and social world with humans for thousands of years, they provide a unique and socially relevant means of investigating a variety of shared human and canine psychological phenomena. Additionally, their trainability allows for neuroimaging to be carried out noninvasively in an awake and unrestrained state. In this review, a brief overview of functional magnetic resonance imaging (fMRI) is followed by an analysis of recent research with dogs using fMRI. Methodological and conceptual concerns found across multiple studies are raised, and solutions to these issues are suggested. With the research capabilities brought by canine functional imaging, findings may improve our understanding of canine cognitive processes, identify neural correlates of behavioral traits, and provide early-life selection measures for dogs in working roles. PMID:29456781

Ted Hall and the science of biological microprobe X-ray analysis: a historical perspective of methodology and biological dividends.

PubMed

Gupta, B L

1991-06-01

This review surveys the emergence of electron probe X-ray microanalysis as a quantitative method for measuring the chemical elements in situ. The extension of the method to the biological sciences under the influence of Ted Hall is reviewed. Some classical experiments by Hall and his colleagues in Cambridge, UK, previously unpublished, are described; as are some of the earliest quantitative results from the cryo-sections obtained in Cambridge and elsewhere. The progress of the methodology is critically evaluated from the earliest starts to the present state of the art. Particular attention has been focused on the application of the method in providing fresh insights into the role of ions in cell and tissue physiology and pathology. A comprehensive list of references is included for a further pursuit of the topics by the interested reader.

Introduction to the Special Section on Racial and Ethnic Identity in Counseling Psychology: Conceptual and Methodological Challenges and Proposed Solutions

ERIC Educational Resources Information Center

Ponterotto, Joseph G.; Mallinckrodt, Brent

2007-01-01

Racial and ethnic identity development have been important topics in counseling psychology research for the last four decades. At present, however, there appears to be some confusion and debate regarding the quality of theory and measurement in the topical area. The present article serves as an introduction to this Journal of Counseling Psychology…

Defining the Ecological Coefficient of Performance for an Aircraft Propulsion System

NASA Astrophysics Data System (ADS)

Şöhret, Yasin

2018-05-01

The aircraft industry, along with other industries, is considered responsible these days regarding environmental issues. Therefore, the performance evaluation of aircraft propulsion systems should be conducted with respect to environmental and ecological considerations. The current paper aims to present the ecological coefficient of performance calculation methodology for aircraft propulsion systems. The ecological coefficient performance is a widely-preferred performance indicator of numerous energy conversion systems. On the basis of thermodynamic laws, the methodology used to determine the ecological coefficient of performance for an aircraft propulsion system is parametrically explained and illustrated in this paper for the first time. For a better understanding, to begin with, the exergy analysis of a turbojet engine is described in detail. Following this, the outputs of the analysis are employed to define the ecological coefficient of performance for a turbojet engine. At the end of the study, the ecological coefficient of performance is evaluated parametrically and discussed depending on selected engine design parameters and performance measures. The author asserts the ecological coefficient of performance to be a beneficial indicator for researchers interested in aircraft propulsion system design and related topics.

High school students presenting science: An interactional sociolinguistic analysis

NASA Astrophysics Data System (ADS)

Bleicher, Robert

Presenting science is an authentic activity of practicing scientists. Thus, effective communication of science is an important skill to nurture in high school students who are learning science. This study examines strategies employed by high school students as they make science presentations; it assesses students' conceptual understandings of particular science topics through their presentations and investigates gender differences. Data are derived from science presentation given by eight high school students, three females and five males who attended a summer science program. Data sources included videotaped presentations, ethnographic fieldnotes, interviews with presenters and members of the audience, and presenter notes and overheads. Presentations were transcribed and submitted to discourse analysis from an interactional sociolinguistic perspective. This article focuses on the methodology employed and how it helps inform the above research questions. The author argues that use of this methodology leads to findings that inform important social-communicative issues in the learning of science. Practical advice for teaching students to present science, implications for use of presentations to assess conceptual learning, and indications of some possible gender differences are discussed.Received: 14 April 1993; Revised: 15 February 1994;

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watson, Jean-Paul; Guttromson, Ross; Silva-Monroy, Cesar

This report has been written for the Department of Energy’s Energy Policy and Systems Analysis Office to inform their writing of the Quadrennial Energy Review in the area of energy resilience. The topics of measuring and increasing energy resilience are addressed, including definitions, means of measuring, and analytic methodologies that can be used to make decisions for policy, infrastructure planning, and operations. A risk-based framework is presented which provides a standard definition of a resilience metric. Additionally, a process is identified which explains how the metrics can be applied. Research and development is articulated that will further accelerate the resiliencemore » of energy infrastructures.« less

On the Research of the Methodology of Mathematization of Pedagogical Science

ERIC Educational Resources Information Center

Perminov, Evgeniy ?.; Anakhov, Sergey V.; Grishin, Anton S.; Savitskiy, Egor S.

2016-01-01

Topicality of the study is driven by the fact that the new fundamental mathematical ideas and methods of mathematics arise in the new era of mathematization of science and have a great influence on the formation of methodological culture of educational research in recent decades. The aim of the article is to identify the important aspects of the…

Innovative Methodology For Detection of Fracture-Controlled Sweet Spots in the Northern Appalachian Basin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacobi, Rober

2007-03-28

This Topical Report (#6 of 9) consists of the figures 3.6-13 to (and including) 3.6-18 (and appropriate figure captions) that accompany the Final Technical Progress Report entitled: “Innovative Methodology for Detection of Fracture-Controlled Sweet Spots in the Northern Appalachian Basin” for DOE/NETL Award DE-AC26-00NT40698.

To What Extent Does Current Scientific Research and Textbook Content Align? A Methodology and Case Study

ERIC Educational Resources Information Center

Bierema, Andrea M.-K.; Schwartz, Renee S.; Gill, Sharon A.

2017-01-01

Recent calls for reform in education recommend science curricula to be based on central ideas instead of a larger number of topics and for alignment between current scientific research and curricula. Because alignment is rarely studied, especially for central ideas, we developed a methodology to discover the extent of alignment between primary…

Release Notes for Whisper-1.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Forrest B.; Rising, Michael Evan; Alwin, Jennifer Louise

Whisper is a statistical analysis package developed in 2014 to support nuclear criticality safety (NCS) validation [1-3]. It uses the sensitivity profile data for an application as computed by MCNP6 [4-6] along with covariance files [7,8] for the nuclear data to determine a baseline upper-subcritical-limit (USL) for the application. Whisper version 1.0 was first developed and used at LANL in 2014 [3]. During 2015-2016, Whisper was updated to version 1.1 [9] and is to be included with the upcoming release of MCNP6.2. This document describes the Whisper-1.1 package that will be included with the MCNP6.2 release during 2017. Specific detailsmore » are provided on the computer systems supported, the software quality assurance (SQA) procedures, installation, and testing. This document does not address other important topics, such as the importance of sensitivity-uncertainty (SU) methods to NCS validation, the theory underlying SU methodology, tutorials on the usage of MCNP-Whisper, practical approaches to using SU methodology to support and extend traditional validation, etc. There are over 50 documents included with Whisper-1.1 and available in the MCNP Reference Collection on the MCNP website (mcnp.lanl.gov) that address all of those topics and more. In this document, however, a complete bibliography of relevant MCNP-Whisper references is provided.« less

Applying Sparse Machine Learning Methods to Twitter: Analysis of the 2012 Change in Pap Smear Guidelines. A Sequential Mixed-Methods Study

PubMed Central

Godbehere, Andrew; Le, Gem; El Ghaoui, Laurent; Sarkar, Urmimala

2016-01-01

Background It is difficult to synthesize the vast amount of textual data available from social media websites. Capturing real-world discussions via social media could provide insights into individuals’ opinions and the decision-making process. Objective We conducted a sequential mixed methods study to determine the utility of sparse machine learning techniques in summarizing Twitter dialogues. We chose a narrowly defined topic for this approach: cervical cancer discussions over a 6-month time period surrounding a change in Pap smear screening guidelines. Methods We applied statistical methodologies, known as sparse machine learning algorithms, to summarize Twitter messages about cervical cancer before and after the 2012 change in Pap smear screening guidelines by the US Preventive Services Task Force (USPSTF). All messages containing the search terms “cervical cancer,” “Pap smear,” and “Pap test” were analyzed during: (1) January 1–March 13, 2012, and (2) March 14–June 30, 2012. Topic modeling was used to discern the most common topics from each time period, and determine the singular value criterion for each topic. The results were then qualitatively coded from top 10 relevant topics to determine the efficiency of clustering method in grouping distinct ideas, and how the discussion differed before vs. after the change in guidelines . Results This machine learning method was effective in grouping the relevant discussion topics about cervical cancer during the respective time periods (~20% overall irrelevant content in both time periods). Qualitative analysis determined that a significant portion of the top discussion topics in the second time period directly reflected the USPSTF guideline change (eg, “New Screening Guidelines for Cervical Cancer”), and many topics in both time periods were addressing basic screening promotion and education (eg, “It is Cervical Cancer Awareness Month! Click the link to see where you can receive a free or low cost Pap test.”) Conclusions It was demonstrated that machine learning tools can be useful in cervical cancer prevention and screening discussions on Twitter. This method allowed us to prove that there is publicly available significant information about cervical cancer screening on social media sites. Moreover, we observed a direct impact of the guideline change within the Twitter messages. PMID:27288093

Product assurance technology efforts: Technical accomplishments

NASA Technical Reports Server (NTRS)

1985-01-01

Product assurance technology topics addressed include: wafer acceptance procedures, test chips, test structures, test chip methodology, fault models, and the Combined Release and Radiation Effects Satellite test chip.

Comparative and Familial Analysis of Handedness in Great Apes

PubMed Central

Hopkins, William D.

2007-01-01

Historically, population-level handedness has been considered a hallmark of human evolution. Whether nonhuman primates exhibit population-level handedness remains a topic of considerable debate. This paper summarizes published data on handedness in great apes. Comparative analysis indicated that chimpanzees and bonobos show population-level right handedness, whereas gorillas and orangutans do not. All ape species showed evidence of population-level handedness when considering specific tasks. Familial analyses in chimpanzees indicated that offspring and maternal (but not paternal) handedness was significantly positively correlated, but this finding was contingent upon the classification criteria used to evaluate hand preference. Overall, the proportion of right handedness is lower in great apes compared with humans, and various methodological and theoretical explanations for this discrepancy are discussed. PMID:16822166

Development of an evidence-based review with recommendations using an online iterative process.

PubMed

Rudmik, Luke; Smith, Timothy L

2011-01-01

The practice of modern medicine is governed by evidence-based principles. Due to the plethora of medical literature, clinicians often rely on systematic reviews and clinical guidelines to summarize the evidence and provide best practices. Implementation of an evidence-based clinical approach can minimize variation in health care delivery and optimize the quality of patient care. This article reports a method for developing an "Evidence-based Review with Recommendations" using an online iterative process. The manuscript describes the following steps involved in this process: Clinical topic selection, Evidence-hased review assignment, Literature review and initial manuscript preparation, Iterative review process with author selection, and Manuscript finalization. The goal of this article is to improve efficiency and increase the production of evidence-based reviews while maintaining the high quality and transparency associated with the rigorous methodology utilized for clinical guideline development. With the rise of evidence-based medicine, most medical and surgical specialties have an abundance of clinical topics which would benefit from a formal evidence-based review. Although clinical guideline development is an important methodology, the associated challenges limit development to only the absolute highest priority clinical topics. As outlined in this article, the online iterative approach to the development of an Evidence-based Review with Recommendations may improve productivity without compromising the quality associated with formal guideline development methodology. Copyright © 2011 American Rhinologic Society-American Academy of Otolaryngic Allergy, LLC.

Sports medicine clinical trial research publications in academic medical journals between 1996 and 2005: an audit of the PubMed MEDLINE database.

PubMed

Nichols, A W

2008-11-01

To identify sports medicine-related clinical trial research articles in the PubMed MEDLINE database published between 1996 and 2005 and conduct a review and analysis of topics of research, experimental designs, journals of publication and the internationality of authorships. Sports medicine research is international in scope with improving study methodology and an evolution of topics. Structured review of articles identified in a search of a large electronic medical database. PubMed MEDLINE database. Sports medicine-related clinical research trials published between 1996 and 2005. Review and analysis of articles that meet inclusion criteria. Articles were examined for study topics, research methods, experimental subject characteristics, journal of publication, lead authors and journal countries of origin and language of publication. The search retrieved 414 articles, of which 379 (345 English language and 34 non-English language) met the inclusion criteria. The number of publications increased steadily during the study period. Randomised clinical trials were the most common study type and the "diagnosis, management and treatment of sports-related injuries and conditions" was the most popular study topic. The knee, ankle/foot and shoulder were the most frequent anatomical sites of study. Soccer players and runners were the favourite study subjects. The American Journal of Sports Medicine had the highest number of publications and shared the greatest international diversity of authorships with the British Journal of Sports Medicine. The USA, Australia, Germany and the UK produced a good number of the lead authorships. In all, 91% of articles and 88% of journals were published in English. Sports medicine-related research is internationally diverse, clinical trial publications are increasing and the sophistication of research design may be improving.

Do existing research summaries on health systems match immunisation managers' needs in middle- and low-income countries? Analysis of GAVI health systems strengthening support

PubMed Central

2011-01-01

Background The GAVI Alliance was created in 2000 to increase access to vaccines. More recently, GAVI has supported evidence-based health systems strengthening to overcome barriers to vaccination. Our objectives were: to explore countries' priorities for health systems strengthening; to describe published research summaries for each priority area in relation to their number, quality and relevance; and to describe the use of national data from surveys in identifying barriers to immunisation. Methods From 44 health systems strengthening proposals submitted to GAVI in 2007 and 2008, we analysed the topics identified, the coverage of these topics by existing systematic reviews and the use of nation-wide surveys with vaccination data to justify the needs identified in the proposals. Results Thirty topics were identified and grouped into three thematic areas: health workforce (10 topics); organisation and management (14); and supply, distribution and maintenance (6). We found 51 potentially relevant systematic reviews, although for the topic that appeared most frequently in the proposals ('Health information systems') no review was identified. Thematic and geographic relevance were generally categorised as "high" in 33 (65%) and 25 (49%) reviews, respectively, but few reviews were categorised as "highly relevant for policy" (7 reviews, 14%). With regard to methodological quality, 14 reviews (27%) were categorised as "high". The number of topics that were addressed by at least one high quality systematic review was: seven of the 10 topics in the 'health workforce' thematic area; six of the 14 topics in the area of 'organisation and management'; and none of the topics in the thematic area of 'supply, distribution and maintenance'. Only twelve of the 39 countries with available national surveys referred to them in their proposals. Conclusion Relevant, high quality research summaries were found for few of the topics identified by managers. Few proposals used national surveys evidence to identify barriers to vaccination. Researchers generating or adapting evidence about health systems need to be more responsive to managers' needs. Use of available evidence from local or national surveys should be strongly encouraged. PMID:21651793

Association between long travel and venous thromboembolic disease: a systematic review and meta-analysis of case-control studies

PubMed Central

Jiménez-Puente, Alberto; Perea-Milla, Emilio

2007-01-01

The term “economy-class syndrome” defines an infrequent episode of venous thromboembolism (VTED) related to a long travel, namely by plane. However, this relation has not clearly been demonstrated by investigators. We carried out a systematic review and a meta-analysis of cases-control studies that had studied this topic. We realised a systematic review of the literature and selected all the case-control studies published. Two authors carried out a methodological evaluation according to the Scottish Intercollegiate Guidelines Network items (concordance was analysed by weighted kappa index), and a systematic analysis of the potential biases of each study was assessed. We carried out the meta-analysis with the data extracted from the studies. We recovered eight cases-control studies. The relation between the antecedent of a long travel and subsequent VTED varied from OR = 1.1 to OR = 4.0 and was found to be significant in four studies. The studies were highly heterogeneous in methodology and so the results obtained about the relation between the long travel and the VTED and the score at SIGN50. Two meta-analysis were carried out: only with travels by plane in which the relation was not significant (OR = 1.21; CI 95%, 0.95–1.55) and with all types of transport, with a slightly significant relation (OR = 1.46; CI95%, 1.24–1.72). We may deduce from this systematic review that there does exist a weak association between episodes of VTED and a long travel, but not by plane specifically. The heterogeneity and the methodological quality of the studies published preclude of more robust conclusions. PMID:17899081

A Pilot Study of a Picture- and Audio-Assisted Self-Interviewing Method (PIASI) for the Study of Sensitive Questions on HIV in the Field

ERIC Educational Resources Information Center

Aarnio, Pauliina; Kulmala, Teija

2016-01-01

Self-interview methods such as audio computer-assisted self-interviewing (ACASI) are used to improve the accuracy of interview data on sensitive topics in large trials. Small field studies on sensitive topics would benefit from methodological alternatives. In a study on male involvement in antenatal HIV testing in a largely illiterate population…

Selection Bias in Students' Evaluation of Teaching: Causes of Student Absenteeism and Its Consequences for Course Ratings and Rankings

ERIC Educational Resources Information Center

Wolbring, Tobias; Treischl, Edgar

2016-01-01

Systematic sampling error due to self-selection is a common topic in methodological research and a key challenge for every empirical study. Since selection bias is often not sufficiently considered as a potential flaw in research on and evaluations in higher education, the aim of this paper is to raise awareness for the topic using the case of…

Methodology and reporting of meta-analyses in the neurosurgical literature.

PubMed

Klimo, Paul; Thompson, Clinton J; Ragel, Brian T; Boop, Frederick A

2014-04-01

Neurosurgeons are inundated with vast amounts of new clinical research on a daily basis, making it difficult and time-consuming to keep up with the latest literature. Meta-analysis is an extension of a systematic review that employs statistical techniques to pool the data from the literature in order to calculate a cumulative effect size. This is done to answer a clearly defined a priori question. Despite their increasing popularity in the neurosurgery literature, meta-analyses have not been scrutinized in terms of reporting and methodology. The authors performed a literature search using PubMed/MEDLINE to locate all meta-analyses that have been published in the JNS Publishing Group journals (Journal of Neurosurgery, Journal of Neurosurgery: Pediatrics, Journal of Neurosurgery: Spine, and Neurosurgical Focus) or Neurosurgery. Accepted checklists for reporting (PRISMA) and methodology (AMSTAR) were applied to each meta-analysis, and the number of items within each checklist that were satisfactorily fulfilled was recorded. The authors sought to answer 4 specific questions: Are meta-analyses improving 1) with time; 2) when the study met their definition of a meta-analysis; 3) when clinicians collaborated with a potential expert in meta-analysis; and 4) when the meta-analysis was the only focus of the paper? Seventy-two meta-analyses were published in the JNS Publishing Group journals and Neurosurgery between 1990 and 2012. The number of published meta-analyses has increased dramatically in the last several years. The most common topics were vascular, and most were based on observational studies. Only 11 papers were prepared using an established checklist. The average AMSTAR and PRISMA scores (proportion of items satisfactorily fulfilled divided by the total number of eligible items in the respective instrument) were 31% and 55%, respectively. Major deficiencies were identified, including the lack of a comprehensive search strategy, study selection and data extraction, assessment of heterogeneity, publication bias, and study quality. Almost one-third of the papers did not meet our basic definition of a meta-analysis. The quality of reporting and methodology was better 1) when the study met our definition of a meta-analysis; 2) when one or more of the authors had experience or expertise in conducting a meta-analysis; 3) when the meta-analysis was not conducted alongside an evaluation of the authors' own data; and 4) in more recent studies. Reporting and methodology of meta-analyses in the neurosurgery literature is excessively variable and overall poor. As these papers are being published with increasing frequency, neurosurgical journals need to adopt a clear definition of a meta-analysis and insist that they be created using checklists for both reporting and methodology. Standardization will ensure high-quality publications.

Critical reflections on methodological challenge in arts and dementia evaluation and research.

PubMed

Gray, Karen; Evans, Simon Chester; Griffiths, Amanda; Schneider, Justine

2017-01-01

Methodological rigour, or its absence, is often a focus of concern for the emerging field of evaluation and research around arts and dementia. However, this paper suggests that critical attention should also be paid to the way in which individual perceptions, hidden assumptions and underlying social and political structures influence methodological work in the field. Such attention will be particularly important for addressing methodological challenges relating to contextual variability, ethics, value judgement and signification identified through a literature review on this topic. Understanding how, where and when evaluators and researchers experience such challenges may help to identify fruitful approaches for future evaluation.

The Utilization of Navy People-Related RDT&E (Research, Development, Test, and Evaluation): Fiscal Year 1983.

DTIC Science & Technology

1984-06-01

emostraion. Tese eserch ool wee deignted and experimental demonstrations wre successfully con- for demonstrations. These research tools wre designated ...Topics 4.02 Instructional Systems Design Methodology Instructional Systems Development and Effectiveness Evaluation .................................... 1...6 53 0 0 67w Report Page 10.07 Human Performance Variables/Factors 10.08 Man-Machine Design Methodology Computer Assisted Methods for Human

Qualitative-Based Methodology to Teaching Qualitative Methodology in Higher Education

ERIC Educational Resources Information Center

Katz, Sara

2015-01-01

There is no defined theory for teaching Qualitative Inquiry, and very few studies have focused on the topic. This study is a qualitative case study focused on the Qualitative Methods course that I teach at a college of education in Israel. The aim of the study is to explore and describe the course, to provide a true picture of my pedagogy, and to…

Bundle Adjustment-Based Stability Analysis Method with a Case Study of a Dual Fluoroscopy Imaging System

NASA Astrophysics Data System (ADS)

Al-Durgham, K.; Lichti, D. D.; Detchev, I.; Kuntze, G.; Ronsky, J. L.

2018-05-01

A fundamental task in photogrammetry is the temporal stability analysis of a camera/imaging-system's calibration parameters. This is essential to validate the repeatability of the parameters' estimation, to detect any behavioural changes in the camera/imaging system and to ensure precise photogrammetric products. Many stability analysis methods exist in the photogrammetric literature; each one has different methodological bases, and advantages and disadvantages. This paper presents a simple and rigorous stability analysis method that can be straightforwardly implemented for a single camera or an imaging system with multiple cameras. The basic collinearity model is used to capture differences between two calibration datasets, and to establish the stability analysis methodology. Geometric simulation is used as a tool to derive image and object space scenarios. Experiments were performed on real calibration datasets from a dual fluoroscopy (DF; X-ray-based) imaging system. The calibration data consisted of hundreds of images and thousands of image observations from six temporal points over a two-day period for a precise evaluation of the DF system stability. The stability of the DF system - for a single camera analysis - was found to be within a range of 0.01 to 0.66 mm in terms of 3D coordinates root-mean-square-error (RMSE), and 0.07 to 0.19 mm for dual cameras analysis. It is to the authors' best knowledge that this work is the first to address the topic of DF stability analysis.

Promoting pedagogical content knowledge development for early career secondary teachers in science and technology using content representations

NASA Astrophysics Data System (ADS)

Williams, John; Eames, Chris; Hume, Anne; Lockley, John

2012-11-01

Background: This research addressed the key area of early career teacher education and aimed to explore the use of a 'content representation' (CoRe) as a mediational tool to develop early career secondary teacher pedagogical content knowledge (PCK). This study was situated in the subject areas of science and technology, where sound teacher knowledge is particularly important to student engagement. Purpose: The study was designed to examine whether such a tool (a CoRe), co-designed by an early career secondary teacher with expert content and pedagogy specialists, can enhance the PCK of early career teachers. The research questions were: How can experts in content and pedagogy work together with early career teachers to develop one science topic CoRe and one technology topic CoRe to support the development of PCK for early career secondary teachers? How does the use of a collaboratively designed CoRe affect the planning of an early career secondary teacher in science or technology? How has engagement in the development and use of an expert-informed CoRe developed an early career teacher's PCK? Sample: The research design incorporated a unique partnership between two expert classroom teachers, two content experts, four early career teachers, and four researchers experienced in science and technology education. Design: This study employed an interpretivist-based methodology and an action research approach within a four-case study design. Data were gathered using qualitative research methods focused on semi-structured interviews, observations and document analysis. Results: The study indicated that CoRes, developed through this collaborative process, helped the early career teachers focus on the big picture of the topic, emphasize particularly relevant areas of content and consider alternative ways of planning for their teaching. Conclusions: This paper presents an analysis of the process of CoRe development by the teacher-expert partnerships and the effect that had on the early career teachers' PCK. In addition, as the same tools and methodology were applied to both a science and a technology teaching context, differences between the two learning areas are discussed.

Experimental analysis of computer system dependability

NASA Technical Reports Server (NTRS)

Iyer, Ravishankar, K.; Tang, Dong

1993-01-01

This paper reviews an area which has evolved over the past 15 years: experimental analysis of computer system dependability. Methodologies and advances are discussed for three basic approaches used in the area: simulated fault injection, physical fault injection, and measurement-based analysis. The three approaches are suited, respectively, to dependability evaluation in the three phases of a system's life: design phase, prototype phase, and operational phase. Before the discussion of these phases, several statistical techniques used in the area are introduced. For each phase, a classification of research methods or study topics is outlined, followed by discussion of these methods or topics as well as representative studies. The statistical techniques introduced include the estimation of parameters and confidence intervals, probability distribution characterization, and several multivariate analysis methods. Importance sampling, a statistical technique used to accelerate Monte Carlo simulation, is also introduced. The discussion of simulated fault injection covers electrical-level, logic-level, and function-level fault injection methods as well as representative simulation environments such as FOCUS and DEPEND. The discussion of physical fault injection covers hardware, software, and radiation fault injection methods as well as several software and hybrid tools including FIAT, FERARI, HYBRID, and FINE. The discussion of measurement-based analysis covers measurement and data processing techniques, basic error characterization, dependency analysis, Markov reward modeling, software-dependability, and fault diagnosis. The discussion involves several important issues studies in the area, including fault models, fast simulation techniques, workload/failure dependency, correlated failures, and software fault tolerance.

Prophylactic antibiotics for burns patients: systematic review and meta-analysis

PubMed Central

Avni, Tomer; Levcovich, Ariela; Ad-El, Dean D; Leibovici, Leonard

2010-01-01

Objective To assess the evidence for prophylactic treatment with systemic antibiotics in burns patients. Design Systematic review and meta-analysis of randomised or quasi-randomised controlled trials recruiting burns inpatients that compared antibiotic prophylaxis (systemic, non-absorbable, or topical) with placebo or no treatment. Data sources PubMed, Cochrane Library, LILACS, Embase, conference proceedings, and bibliographies. No language, date, or publication status restrictions were imposed. Review methods Two reviewers independently extracted data. The primary outcome was all cause mortality. Risk or rate ratios with 95% confidence intervals were pooled with a fixed effect model if no heterogeneity was present. Results 17 trials were included. Trials that assessed systemic antibiotic prophylaxis given for 4-14 days after admission showed a significant reduction in all cause mortality (risk ratio 0.54, 95% confidence interval 0.34 to 0.87, five trials). The corresponding number needed to treat was 8 (5 to 33), with a control event rate of 26%. Perioperative non-absorbable or topical antibiotics alone did not significantly affect mortality. There was a reduction in pneumonia with systemic prophylaxis and a reduction in wound infections with perioperative prophylaxis. Staphylococcus aureus infection or colonisation was reduced with anti-staphylococcal antibiotics. In three trials, resistance to the antibiotic used for prophylaxis significantly increased (rate ratio 2.84, 1.38 to 5.83). The overall methodological quality of the trials was poor. Conclusions Prophylaxis with systemic antibiotics has a beneficial effect in burns patients, but the methodological quality of the data is weak. As such prophylaxis is currently not recommended for patients with severe burns other than perioperatively, there is a need for randomised controlled trials to assess its use. PMID:20156911

Concept mapping and network analysis: an analytic approach to measure ties among constructs.

PubMed

Goldman, Alyssa W; Kane, Mary

2014-12-01

Group concept mapping is a mixed-methods approach that helps a group visually represent its ideas on a topic of interest through a series of related maps. The maps and additional graphics are useful for planning, evaluation and theory development. Group concept maps are typically described, interpreted and utilized through points, clusters and distances, and the implications of these features in understanding how constructs relate to one another. This paper focuses on the application of network analysis to group concept mapping to quantify the strength and directionality of relationships among clusters. The authors outline the steps of this analysis, and illustrate its practical use through an organizational strategic planning example. Additional benefits of this analysis to evaluation projects are also discussed, supporting the overall utility of this supplemental technique to the standard concept mapping methodology. Copyright © 2014 Elsevier Ltd. All rights reserved.

MS-based analytical methodologies to characterize genetically modified crops.

PubMed

García-Cañas, Virginia; Simó, Carolina; León, Carlos; Ibáñez, Elena; Cifuentes, Alejandro

2011-01-01

The development of genetically modified crops has had a great impact on the agriculture and food industries. However, the development of any genetically modified organism (GMO) requires the application of analytical procedures to confirm the equivalence of the GMO compared to its isogenic non-transgenic counterpart. Moreover, the use of GMOs in foods and agriculture faces numerous criticisms from consumers and ecological organizations that have led some countries to regulate their production, growth, and commercialization. These regulations have brought about the need of new and more powerful analytical methods to face the complexity of this topic. In this regard, MS-based technologies are increasingly used for GMOs analysis to provide very useful information on GMO composition (e.g., metabolites, proteins). This review focuses on the MS-based analytical methodologies used to characterize genetically modified crops (also called transgenic crops). First, an overview on genetically modified crops development is provided, together with the main difficulties of their analysis. Next, the different MS-based analytical approaches applied to characterize GM crops are critically discussed, and include "-omics" approaches and target-based approaches. These methodologies allow the study of intended and unintended effects that result from the genetic transformation. This information is considered to be essential to corroborate (or not) the equivalence of the GM crop with its isogenic non-transgenic counterpart. Copyright © 2010 Wiley Periodicals, Inc.

Exploration of Perinatal Pharmacokinetic Issues

EPA Pesticide Factsheets

Identify information that would inform the development of future test guidance documents related to this topic, and identify information or approaches that would assist EPA in improving existing noncancer risk assessment methodologies.

Let's 'play' with molecular pharmacology.

PubMed

Choudhury, Supriyo; Pradhan, Richeek; Sengupta, Gairik; Das, Manisha; Chatterjee, Manojit; Roy, Ranendra Kumar; Chatterjee, Suparna

2015-01-01

Understanding concepts of molecular mechanisms of drug action involves sequential visualization of physiological processes and drug effects, a task that can be difficult at an undergraduate level. Role-play is a teaching-learning methodology whereby active participation of students as well as clear visualization of the phenomenon is used to convey complex physiological concepts. However, its use in teaching drug action, a process that demands understanding of a second level of complexity over the physiological process, has not been investigated. We hypothesized that role-play can be an effective and well accepted method for teaching molecular pharmacology. In an observational study, students were guided to perform a role-play on a selected topic involving drug activity. Students' gain in knowledge was assessed comparing validated pre- and post-test questionnaires as well as class average normalized gain. The acceptance of role-play among undergraduate medical students was evaluated by Likert scale analysis and thematic analysis of their open-ended written responses. Significant improvement in knowledge (P < 0.001) was noted in the pre- to post-test knowledge scores, while a high gain in class average normalized score was evident. In Likert scale analysis, most students (93%) expressed that role-play was an acceptable way of teaching. In a thematic analysis, themes of both strengths and weaknesses of the session emerged. Role-play can be effectively utilized while teaching selected topics of molecular pharmacology in undergraduate medical curricula.

[Qualitative analysis of topics related to the quality of life of people with disabilities].

PubMed

Cilleros, María Victoria Martín; Gómez, Maria Cruz Sánchez

2016-08-01

Quality of life is a concept that reflects the subjective perception of individuals in relation to their degree of satisfaction with their living conditions. It is a concept that involves putting the individual at the forefront, talking about the quality of the professionals involved and influencing the development of programs and the provision of services. The article reflects the opinions that different agents have in relation to disability on given topics related to the model of quality of life such as: the relationship between different agents; the necessary training of professionals in the field of health and/or disability; and the existence of the presence of the participation in society of people with disabilities. Using qualitative methodology, the arguments of the participants in these three issues are discussed. The verbiage, the conceptual map and the analysis of content, performed after the encoding of information, made it possible to detect the perceived needs and satisfaction with the care of the different services. The profile of the qualified professional within the scope of disability is outlined. Proposals for the future are contained in the conclusions, ensuring the improvement of the quality of life of people with disabilities.

Use of Web-based library resources by medical students in community and ambulatory settings*

PubMed Central

Tannery, Nancy Hrinya; Foust, Jill E.; Gregg, Amy L.; Hartman, Linda M.; Kuller, Alice B.; Worona, Paul; Tulsky, Asher A.

2002-01-01

Purpose: The purpose was to evaluate the use of Web-based library resources by third-year medical students. Setting/Participants/Resources: Third-year medical students (147) in a twelve-week multidisciplinary primary care rotation in community and ambulatory settings. Methodology: Individual user surveys and log file analysis of Website were used. Results/Outcomes: Twenty resource topics were compiled into a Website to provide students with access to electronic library resources from any community-based clerkship location. These resource topics, covering subjects such as hypertension and back pain, linked to curriculum training problems, full-text journal articles, MEDLINE searches, electronic book chapters, and relevant Websites. More than half of the students (69%) accessed the Website on a daily or weekly basis. Over 80% thought the Website was a valuable addition to their clerkship. Discussion/Conclusion: Web-based information resources can provide curriculum support to students for whom access to the library is difficult and time consuming. PMID:12113515

ON IDENTIFIABILITY OF NONLINEAR ODE MODELS AND APPLICATIONS IN VIRAL DYNAMICS

PubMed Central

MIAO, HONGYU; XIA, XIAOHUA; PERELSON, ALAN S.; WU, HULIN

2011-01-01

Ordinary differential equations (ODE) are a powerful tool for modeling dynamic processes with wide applications in a variety of scientific fields. Over the last 2 decades, ODEs have also emerged as a prevailing tool in various biomedical research fields, especially in infectious disease modeling. In practice, it is important and necessary to determine unknown parameters in ODE models based on experimental data. Identifiability analysis is the first step in determing unknown parameters in ODE models and such analysis techniques for nonlinear ODE models are still under development. In this article, we review identifiability analysis methodologies for nonlinear ODE models developed in the past one to two decades, including structural identifiability analysis, practical identifiability analysis and sensitivity-based identifiability analysis. Some advanced topics and ongoing research are also briefly reviewed. Finally, some examples from modeling viral dynamics of HIV, influenza and hepatitis viruses are given to illustrate how to apply these identifiability analysis methods in practice. PMID:21785515

Analysis of the interaction between experimental and applied behavior analysis.

PubMed

Virues-Ortega, Javier; Hurtado-Parrado, Camilo; Cox, Alison D; Pear, Joseph J

2014-01-01

To study the influences between basic and applied research in behavior analysis, we analyzed the coauthorship interactions of authors who published in JABA and JEAB from 1980 to 2010. We paid particular attention to authors who published in both JABA and JEAB (dual authors) as potential agents of cross-field interactions. We present a comprehensive analysis of dual authors' coauthorship interactions using social networks methodology and key word analysis. The number of dual authors more than doubled (26 to 67) and their productivity tripled (7% to 26% of JABA and JEAB articles) between 1980 and 2010. Dual authors stood out in terms of number of collaborators, number of publications, and ability to interact with multiple groups within the field. The steady increase in JEAB and JABA interactions through coauthors and the increasing range of topics covered by dual authors provide a basis for optimism regarding the progressive integration of basic and applied behavior analysis. © Society for the Experimental Analysis of Behavior.

Opportunities for research in aerothermodynamics

NASA Technical Reports Server (NTRS)

Graham, R. W.

1983-01-01

"Aerothermodynamics' involves the disciplines of chemistry, thermodynamics, fluid mechanics and heat transfer which have collaborative importance in propulsion systems. There are growing opportunities for the further application of these disciplines to improve the methodology for the design of advanced gas turbines; particularly, the combustor and turbine. Design procedures follow empirical or cut and try guidelines. The tremendous advances in computational analysis and in instrumentation techniques hold promise for research answers to complex physical processes that are currently not well understood. The transfer of basic research understanding to engineering design should result in shorter, less expensive development commitments for engines. The status and anticipated opportunities in research topics relevant to combustors and turbines is reviewed.

Cultural analysis of communication behaviors among juveniles in a correctional facility.

PubMed

Sanger, D D; Creswell, J W; Dworak, J; Schultz, L

2000-01-01

This study addressed communication behaviors of female juvenile delinquents in a correctional facility. Qualitative methodology was used to study 78 participants ranging in age from 13.1 to 18.9 (years; months), over a five-month period. Data collection consisted of observations, participant observation, interviews, and a review of documents. Additionally, participants were tested on the Clinical Evaluation of Language Fundamentals-3. Listening and following rules, utterance types, topics of conversion, politeness, and conversational management emerged as themes. Findings indicated that as many as 22% of participants were potential candidates for language services. Implications for speech-language pathologists (SLPs) providing communication services will be provided.

Increased User Satisfaction Through an Improved Message System

NASA Technical Reports Server (NTRS)

Weissert, C. L.

1997-01-01

With all of the enhancements in software methodology and testing, there is no guarantee that software can be delivered such that no user errors occur, How to handle these errors when they occur has become a major research topic within human-computer interaction (HCI). Users of the Multimission Spacecraft Analysis Subsystem(MSAS) at the Jet Propulsion Laboratory (JPL), a system of X and motif graphical user interfaces for analyzing spacecraft data, complained about the lack of information about the error cause and have suggested that recovery actions be included in the system error messages...The system was evaluated through usability surveys and was shown to be successful.

Complex temporal topic evolution modelling using the Kullback-Leibler divergence and the Bhattacharyya distance.

PubMed

Andrei, Victor; Arandjelović, Ognjen

2016-12-01

The rapidly expanding corpus of medical research literature presents major challenges in the understanding of previous work, the extraction of maximum information from collected data, and the identification of promising research directions. We present a case for the use of advanced machine learning techniques as an aide in this task and introduce a novel methodology that is shown to be capable of extracting meaningful information from large longitudinal corpora and of tracking complex temporal changes within it. Our framework is based on (i) the discretization of time into epochs, (ii) epoch-wise topic discovery using a hierarchical Dirichlet process-based model, and (iii) a temporal similarity graph which allows for the modelling of complex topic changes. More specifically, this is the first work that discusses and distinguishes between two groups of particularly challenging topic evolution phenomena: topic splitting and speciation and topic convergence and merging, in addition to the more widely recognized emergence and disappearance and gradual evolution. The proposed framework is evaluated on a public medical literature corpus.

Trend of the research on construction and demolition waste management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yuan Hongping, E-mail: hpyuan2005@gmail.com; Shen Liyin, E-mail: bsshen@polyu.edu.hk

2011-04-15

Research interests in addressing construction and demolition (C and D) waste management issues have resulted in a large amount of publications during the last decade. This study demonstrates that there is no systematic examination on the research development in literature in the discipline of C and D waste management. This study presents the latest research trend in the discipline through analyzing the publications from 2000 to 2009 in eight major international journals. The analysis is conducted on the number of papers published annually, main authors' contributions, research methods and data analysis methods adopted, and research topics covered. The results exhibitmore » an increasing research interest in C and D waste management in recent years. Researchers from developed economies have contributed significantly to the development of the research in the discipline. Some developing countries such as Malaysia and China have also been making good efforts in promoting C and D waste management research. The findings from this study also indicate that survey and case study are major methods for data collection, and the data are mostly processed through descriptive analysis. It is anticipated that more future studies on C and D waste management will be led by researchers from developing economies, where construction works will remain their major economic activities. On the other hand, more sophisticated modeling and simulating techniques have been used effectively in a number of studies on C and D waste management research, and this is considered a major methodology for future research in the discipline. C and D waste management will continue to be a hot research topic in the future, in particularly, the importance of human factors in C and D waste management has emerged as a new challenging topic.« less

Trend of the research on construction and demolition waste management.

PubMed

Yuan, Hongping; Shen, Liyin

2011-04-01

Research interests in addressing construction and demolition (C&D) waste management issues have resulted in a large amount of publications during the last decade. This study demonstrates that there is no systematic examination on the research development in literature in the discipline of C&D waste management. This study presents the latest research trend in the discipline through analyzing the publications from 2000 to 2009 in eight major international journals. The analysis is conducted on the number of papers published annually, main authors' contributions, research methods and data analysis methods adopted, and research topics covered. The results exhibit an increasing research interest in C&D waste management in recent years. Researchers from developed economies have contributed significantly to the development of the research in the discipline. Some developing countries such as Malaysia and China have also been making good efforts in promoting C&D waste management research. The findings from this study also indicate that survey and case study are major methods for data collection, and the data are mostly processed through descriptive analysis. It is anticipated that more future studies on C&D waste management will be led by researchers from developing economies, where construction works will remain their major economic activities. On the other hand, more sophisticated modeling and simulating techniques have been used effectively in a number of studies on C&D waste management research, and this is considered a major methodology for future research in the discipline. C&D waste management will continue to be a hot research topic in the future, in particularly, the importance of human factors in C&D waste management has emerged as a new challenging topic. Copyright © 2010 Elsevier Ltd. All rights reserved.

What does 'race' have to do with medical education research?

PubMed

Muzzin, Linda; Mickleborough, Tim

2013-08-01

We live in a world of ethnoracial conflict. This is confirmed every day by opening and reading the newspaper. This everyday world seems far away in the pages of a medical education journal, but is it? The goal of this paper is to suggest that one need not look very far in medical education to encounter ethnoracial issues, and further, that research methods that are not ethnoracially biased must be employed to study these topics. We will draw attention to the relevance of employing an ethical conceptual approach to research involving 'race' by demonstrating how one author researching internationally educated health professionals has put 'race' front and centre in his analysis. He does this by using a postcolonial method of analysis termed a 'doubled-research' technique that sets up categories such as 'race' but then decolonizes them to avoid essentialism or stereotyping. We compare this method to another mainstream method employed for the same topic of inquiry which has sidelined 'race' in the analysis, potentially hiding findings about ethnoracial relations involving health professionals in our 'multicultural' society. This demonstration leads to the important question of whether research methods can be epistemologically racist-a question that has been raised about conventional research on education in general. Our argument is not meant to be the last word on this topic, but the first in this journal. We conclude that there is an internal ethics or axiology within research perspectives and methodologies that needs to be examined where ethnoracial issues are prominent. The use of mainstream approaches to undertake research can unintentionally 'leave unsaid' central aspects of what is researched while antiracist methods such as the one described in this article can open up the data to allow for a richer and deeper understanding of the problem. © 2013 John Wiley & Sons Ltd.

Comparative and familial analysis of handedness in great apes.

PubMed

Hopkins, William D

2006-07-01

Historically, population-level handedness has been considered a hallmark of human evolution. Whether nonhuman primates exhibit population-level handedness remains a topic of considerable debate. This paper summarizes published data on handedness in great apes. Comparative analysis indicated that chimpanzees and bonobos show population-level right handedness, whereas gorillas and orangutans do not. All ape species showed evidence of population-level handedness when considering specific tasks. Familial analyses in chimpanzees indicated that offspring and maternal (but not paternal) handedness was significantly positively correlated, but this finding was contingent upon the classification criteria used to evaluate hand preference. Overall, the proportion of right handedness is lower in great apes compared with humans, and various methodological and theoretical explanations for this discrepancy are discussed. Copyright (c) 2006 APA, all rights reserved.

Linguistic methodology for the analysis of aviation accidents

NASA Technical Reports Server (NTRS)

Goguen, J. A.; Linde, C.

1983-01-01

A linguistic method for the analysis of small group discourse, was developed and the use of this method on transcripts of commercial air transpot accidents is demonstrated. The method identifies the discourse types that occur and determine their linguistic structure; it identifies significant linguistic variables based upon these structures or other linguistic concepts such as speech act and topic; it tests hypotheses that support significance and reliability of these variables; and it indicates the implications of the validated hypotheses. These implications fall into three categories: (1) to train crews to use more nearly optimal communication patterns; (2) to use linguistic variables as indices for aspects of crew performance such as attention; and (3) to provide guidelines for the design of aviation procedures and equipment, especially those that involve speech.

A Computational Approach to Qualitative Analysis in Large Textual Datasets

PubMed Central

Evans, Michael S.

2014-01-01

In this paper I introduce computational techniques to extend qualitative analysis into the study of large textual datasets. I demonstrate these techniques by using probabilistic topic modeling to analyze a broad sample of 14,952 documents published in major American newspapers from 1980 through 2012. I show how computational data mining techniques can identify and evaluate the significance of qualitatively distinct subjects of discussion across a wide range of public discourse. I also show how examining large textual datasets with computational methods can overcome methodological limitations of conventional qualitative methods, such as how to measure the impact of particular cases on broader discourse, how to validate substantive inferences from small samples of textual data, and how to determine if identified cases are part of a consistent temporal pattern. PMID:24498398

Cost collection and analysis for health economic evaluation.

PubMed

Smith, Kristine A; Rudmik, Luke

2013-08-01

To improve the understanding of common health care cost collection, estimation, analysis, and reporting methodologies. Ovid MEDLINE (1947 to December 2012), Cochrane Central register of Controlled Trials, Database of Systematic Reviews, Health Technology Assessment, and National Health Service Economic Evaluation Database. This article discusses the following cost collection methods: defining relevant resources, quantification of consumed resources, and resource valuation. It outlines the recommendations for cost reporting in economic evaluations and reviews the techniques on how to handle cost data uncertainty. Last, it discusses the controversial topics of future costs and patient productivity losses. Health care cost collection and estimation can be challenging, and an organized approach is required to optimize accuracy of economic evaluation outcomes. Understanding health care cost collection and estimation techniques will improve both critical appraisal and development of future economic evaluations.

Methodological quality and descriptive characteristics of prosthodontic-related systematic reviews.

PubMed

Aziz, T; Compton, S; Nassar, U; Matthews, D; Ansari, K; Flores-Mir, C

2013-04-01

Ideally, healthcare systematic reviews (SRs) should be beneficial to practicing professionals in making evidence-based clinical decisions. However, the conclusions drawn from SRs are directly related to the quality of the SR and of the included studies. The aim was to investigate the methodological quality and key descriptive characteristics of SRs published in prosthodontics. Methodological quality was analysed using the Assessment of Multiple Reviews (AMSTAR) tool. Several electronic resources (MEDLINE, EMBASE, Web of Science and American Dental Association's Evidence-based Dentistry website) were searched. In total 106 SRs were located. Key descriptive characteristics and methodological quality features were gathered and assessed, and descriptive and inferential statistical testing performed. Most SRs in this sample originated from the European continent followed by North America. Two to five authors conducted most SRs; the majority was affiliated with academic institutions and had prior experience publishing SRs. The majority of SRs were published in specialty dentistry journals, with implant or implant-related topics, the primary topics of interest for most. According to AMSTAR, most quality aspects were adequately fulfilled by less than half of the reviews. Publication bias and grey literature searches were the most poorly adhered components. Overall, the methodological quality of the prosthodontic-related systematic was deemed limited. Future recommendations would include authors to have prior training in conducting SRs and for journals to include a universal checklist that should be adhered to address all key characteristics of an unbiased SR process. © 2013 Blackwell Publishing Ltd.

'Let the heart speak out'--interviewing practices by psychiatrists from two different traditions.

PubMed

Pinto, Diana; Ribeiro, Branca Telles; Lopes Dantas, Maria Tereza

2005-01-01

In the present article, we investigate the extent to which professional theories that underlie, inform, and guide the interviewing practices of two psychiatrists (a neuropsychiatrist and a psychoanalyst) are discursively displayed in their ways of conducting a psychiatric interview. This study analyses excerpts from two audio-recorded psychiatric interviews held at the Institute of Psychiatry of the Federal University of Rio de Janeiro. It follows theoretical and methodological frameworks derived from interactional sociolinguistics. Ethnographic data and research interviews with both clinicians also ground our discussion. Using frame analysis as a central tool, we found that the psychiatrist who subscribes to a neuropsychiatric orientation displays a concern on assessing the patient's cognitive processes, and shifts topics away from the patient's delusions to (re)introduce the institutional frame of the psychiatric interview. By contrast, the psychiatrist who holds a psychoanalytic orientation towards interviewing not only listens attentively to very personal topics introduced by the patient, but also sustains and develops these topics. Most of all, she proposes and stays within conversational frames. In keeping a dual understanding about their practices in the interview situation, both doctors balance the need to follow the institutional agenda and the need to listen to the patient, despite their different theoretical orientations.

A methodological overview on molecular preimplantation genetic diagnosis and screening: a genomic future?

PubMed

Vendrell, Xavier; Bautista-Llácer, Rosa

2012-12-01

The genetic diagnosis and screening of preimplantation embryos generated by assisted reproduction technology has been consolidated in the prenatal care framework. The rapid evolution of DNA technologies is tending to molecular approaches. Our intention is to present a detailed methodological view, showing different diagnostic strategies based on molecular techniques that are currently applied in preimplantation genetic diagnosis. The amount of DNA from one single, or a few cells, obtained by embryo biopsy is a limiting factor for the molecular analysis. In this sense, genetic laboratories have developed molecular protocols considering this restrictive condition. Nevertheless, the development of whole-genome amplification methods has allowed preimplantation genetic diagnosis for two or more indications simultaneously, like the selection of histocompatible embryos plus detection of monogenic diseases or aneuploidies. Moreover, molecular techniques have permitted preimplantation genetic screening to progress, by implementing microarray-based comparative genome hybridization. Finally, a future view of the embryo-genetics field based on molecular advances is proposed. The normalization, cost-effectiveness analysis, and new technological tools are the next topics for preimplantation genetic diagnosis and screening. Concomitantly, these additions to assisted reproduction technologies could have a positive effect on the schedules of preimplantation studies.

Towards a methodology for cluster searching to provide conceptual and contextual "richness" for systematic reviews of complex interventions: case study (CLUSTER).

PubMed

Booth, Andrew; Harris, Janet; Croot, Elizabeth; Springett, Jane; Campbell, Fiona; Wilkins, Emma

2013-09-28

Systematic review methodologies can be harnessed to help researchers to understand and explain how complex interventions may work. Typically, when reviewing complex interventions, a review team will seek to understand the theories that underpin an intervention and the specific context for that intervention. A single published report from a research project does not typically contain this required level of detail. A review team may find it more useful to examine a "study cluster"; a group of related papers that explore and explain various features of a single project and thus supply necessary detail relating to theory and/or context.We sought to conduct a preliminary investigation, from a single case study review, of techniques required to identify a cluster of related research reports, to document the yield from such methods, and to outline a systematic methodology for cluster searching. In a systematic review of community engagement we identified a relevant project - the Gay Men's Task Force. From a single "key pearl citation" we conducted a series of related searches to find contextually or theoretically proximate documents. We followed up Citations, traced Lead authors, identified Unpublished materials, searched Google Scholar, tracked Theories, undertook ancestry searching for Early examples and followed up Related projects (embodied in the CLUSTER mnemonic). Our structured, formalised procedure for cluster searching identified useful reports that are not typically identified from topic-based searches on bibliographic databases. Items previously rejected by an initial sift were subsequently found to inform our understanding of underpinning theory (for example Diffusion of Innovations Theory), context or both. Relevant material included book chapters, a Web-based process evaluation, and peer reviewed reports of projects sharing a common ancestry. We used these reports to understand the context for the intervention and to explore explanations for its relative lack of success. Additional data helped us to challenge simplistic assumptions on the homogeneity of the target population. A single case study suggests the potential utility of cluster searching, particularly for reviews that depend on an understanding of context, e.g. realist synthesis. The methodology is transparent, explicit and reproducible. There is no reason to believe that cluster searching is not generalizable to other review topics. Further research should examine the contribution of the methodology beyond improved yield, to the final synthesis and interpretation, possibly by utilizing qualitative sensitivity analysis.

Space-Policy Education: Contexts and Constraints, Content and Methodology

DTIC Science & Technology

2016-04-20

universities, asked, “How do you teach space policy?” Her question made me think about the various teaching methodologies we use at the National Security Space...Do we teach the right things effectively? I’ve attended a number of forums regarding education and space-related topics but have never participated...likely to use? The agenda also included a survey of different types of instructional methods and their relative pros and cons. Unsurprisingly, we

Cyberframing Cancer: An Exploratory Investigation of Valenced Cybercoping on Cancer Blogs.

PubMed

Donovan, Erin E; Nelson, Erin C; Scheinfeld, Emily

2017-01-01

Although scholarship on coping with cancer implies many ways that coping is communicative, the discursive features of coping have been understudied. The purpose of the present investigation was to theorize the content of cancer blogs, a form of cybercoping, by examining valenced coping-relevant frames that bloggers use to describe their experiences with cancer. This research is both theoretically and methodologically innovative. Theoretically, we advance the concept of cyberframing by connecting the rather disconnected literatures on coping and framing and by studying this topic from a communication perspective. Methodologically, this is one of the few studies of coping with cancer that has used naturally occurring communication data to its advantage. A content analysis of cancer blog entries (N = 194) indicated that more than 90% of cancer blog posts were embedded in a valenced frame. The frames were either negative, positive, or balanced; balanced frames varied in the intensity of the valence. The most common frames were positive and balanced with low affect.

Gait Partitioning Methods: A Systematic Review

PubMed Central

Taborri, Juri; Palermo, Eduardo; Rossi, Stefano; Cappa, Paolo

2016-01-01

In the last years, gait phase partitioning has come to be a challenging research topic due to its impact on several applications related to gait technologies. A variety of sensors can be used to feed algorithms for gait phase partitioning, mainly classifiable as wearable or non-wearable. Among wearable sensors, footswitches or foot pressure insoles are generally considered as the gold standard; however, to overcome some inherent limitations of the former, inertial measurement units have become popular in recent decades. Valuable results have been achieved also though electromyography, electroneurography, and ultrasonic sensors. Non-wearable sensors, such as opto-electronic systems along with force platforms, remain the most accurate system to perform gait analysis in an indoor environment. In the present paper we identify, select, and categorize the available methodologies for gait phase detection, analyzing advantages and disadvantages of each solution. Finally, we comparatively examine the obtainable gait phase granularities, the usable computational methodologies and the optimal sensor placements on the targeted body segments. PMID:26751449

Gait Partitioning Methods: A Systematic Review.

PubMed

Taborri, Juri; Palermo, Eduardo; Rossi, Stefano; Cappa, Paolo

2016-01-06

In the last years, gait phase partitioning has come to be a challenging research topic due to its impact on several applications related to gait technologies. A variety of sensors can be used to feed algorithms for gait phase partitioning, mainly classifiable as wearable or non-wearable. Among wearable sensors, footswitches or foot pressure insoles are generally considered as the gold standard; however, to overcome some inherent limitations of the former, inertial measurement units have become popular in recent decades. Valuable results have been achieved also though electromyography, electroneurography, and ultrasonic sensors. Non-wearable sensors, such as opto-electronic systems along with force platforms, remain the most accurate system to perform gait analysis in an indoor environment. In the present paper we identify, select, and categorize the available methodologies for gait phase detection, analyzing advantages and disadvantages of each solution. Finally, we comparatively examine the obtainable gait phase granularities, the usable computational methodologies and the optimal sensor placements on the targeted body segments.

Clinical audit, a valuable tool to improve quality of care: General methodology and applications in nephrology.

PubMed

Esposito, Pasquale; Dal Canton, Antonio

2014-11-06

Evaluation and improvement of quality of care provided to the patients are of crucial importance in the daily clinical practice and in the health policy planning and financing. Different tools have been developed, including incident analysis, health technology assessment and clinical audit. The clinical audit consist of measuring a clinical outcome or a process, against well-defined standards set on the principles of evidence-based medicine in order to identify the changes needed to improve the quality of care. In particular, patients suffering from chronic renal diseases, present many problems that have been set as topics for clinical audit projects, such as hypertension, anaemia and mineral metabolism management. Although the results of these studies have been encouraging, demonstrating the effectiveness of audit, overall the present evidence is not clearly in favour of clinical audit. These findings call attention to the need to further studies to validate this methodology in different operating scenarios. This review examines the principle of clinical audit, focusing on experiences performed in nephrology settings.

Archaeological Chemistry.

ERIC Educational Resources Information Center

Zurer, Pamela S.

1983-01-01

Research projects and methodology in archeochemistry are discussed. Topics include radiocarbon dating, thermoluminescence, amino acid dating, obsidian hydration dating, bone studies, metals/metallurgy, pottery, stone/glass, and future directions. Includes reports on funding, insights into nuclear waste/environmental problems provided by…

Worldwide trends in volume and quality of published protocols of randomized controlled trials

PubMed Central

Alldinger, Ingo; Cieslak, Kasia P.; Wennink, Roos; Clarke, Mike; Ali, Usama Ahmed; Besselink, Marc G. H.

2017-01-01

Introduction Publishing protocols of randomized controlled trials (RCT) facilitates a more detailed description of study rational, design, and related ethical and safety issues, which should promote transparency. Little is known about how the practice of publishing protocols developed over time. Therefore, this study describes the worldwide trends in volume and methodological quality of published RCT protocols. Methods A systematic search was performed in PubMed and EMBASE, identifying RCT protocols published over a decade from 1 September 2001. Data were extracted on quality characteristics of RCT protocols. The primary outcome, methodological quality, was assessed by individual methodological characteristics (adequate generation of allocation, concealment of allocation and intention-to-treat analysis). A comparison was made by publication period (First, September 2001- December 2004; Second, January 2005-May 2008; Third, June 2008-September 2011), geographical region and medical specialty. Results The number of published RCT protocols increased from 69 in the first, to 390 in the third period (p<0.0001). Internal medicine and paediatrics were the most common specialty topics. Whereas most published RCT protocols in the first period originated from North America (n = 30, 44%), in the second and third period this was Europe (respectively, n = 65, 47% and n = 190, 48%, p = 0.02). Quality of RCT protocols was higher in Europe and Australasia, compared to North America (OR = 0.63, CI = 0.40–0.99, p = 0.04). Adequate generation of allocation improved with time (44%, 58%, 67%, p = 0.001), as did concealment of allocation (38%, 53%, 55%, p = 0.03). Surgical protocols had the highest quality among the three specialty topics used in this study (OR = 1.94, CI = 1.09–3.45, p = 0.02). Conclusion Publishing RCT protocols has become popular, with a five-fold increase in the past decade. The quality of published RCT protocols also improved, although variation between geographical regions and across medical specialties was seen. This emphasizes the importance of international standards of comprehensive training in RCT methodology. PMID:28296925

Topical anaesthetics for pain control during repair of dermal laceration.

PubMed

Tayeb, Baraa O; Eidelman, Anthony; Eidelman, Cristy L; McNicol, Ewan D; Carr, Daniel B

2017-02-22

Topical local anaesthetics provide effective analgesia for patients undergoing numerous superficial procedures, including repair of dermal lacerations. The need for cocaine in topical anaesthetic formulations has been questioned because of concern about adverse effects, thus novel preparations of cocaine-free anaesthetics have been developed. This review was originally published in 2011 and has been updated in 2017. To assess whether benefits of non-invasive topical anaesthetic application occur at the expense of decreased analgesic efficacy. To compare the efficacy of various single-component or multi-component topical anaesthetic agents for repair of dermal lacerations. To determine the clinical necessity for topical application of the ester anaesthetic, cocaine. For this updated review, we searched the following databases: Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 11), Cumulative Index to Nursing and Allied Health Literature (CINAHL; 2010 to December 2016), Embase (2010 to December 2016) and MEDLINE (2010 to December 2016). We did not limit this search by language or format of publication. We contacted manufacturers, international scientific societies and researchers in the field. Weemailed selected journalsand reviewed meta-registers of ongoing trials. For the previous version of this review, we searched these databases to November 2010. We included randomized controlled trials (RCTs) that evaluated the efficacy and safety of topical anaesthetics for repair of dermal laceration in adult and paediatric participants. Two review authors independently assessed trial quality and extracted data. We contacted study authors for additional information when needed. We collected adverse event information from trial reports. We assessed methodological risk of bias for each included study and employed the GRADE approach to assess the overall quality of the evidence. The present updated review included 25 RCTs involving 3278 participants. The small number of trials in each comparison group and the heterogeneity of outcome measures precluded quantitative analysis of data for all but one outcome: pain intensity. In two pooled studies, the mean self-reported visual analogue scale (VAS; 0 to 100 mm) score for topical prilocaine-phenylephrine (PP) was higher than the mean self-reported VAS (0 to 100 mm) score for topical tetracaine-epinephrine-cocaine (TAC) by 5.59 points (95% confidence interval (CI) 2.16 to 13.35). Most trials that compared infiltrated and topical anaesthetics were at high risk of bias, which is likely to have affected their results. Researchers found that several cocaine-free topical anaesthetics provided effective analgesic efficacy. However, data regarding the efficacy of each topical agent are based mostly on single comparisons in trials with unclear or high risk of bias. Mild, self-limited erythematous skin induration occurred in one of 1042 participants who had undergone application of TAC. Investigators reported no serious complications among any of the participants treated with cocaine-based or cocaine-free topical anaesthetics. The overall quality of the evidence according to the GRADE system is low owing to limitations in design and implementation, imprecision of results and high probability of publication bias (selective reporting of data). Additional well-designed RCTs with low risk of bias are necessary before definitive conclusions can be reached. We have found two new studies published since the last version of this review was prepared. We have added these studies to those previously included and have conducted an updated analysis, which resulted in the same review conclusions as were presented previously.Mostly descriptive analysis indicates that topical anaesthetics may offer an efficacious, non-invasive means of providing analgesia before suturing of dermal lacerations. Use of cocaine-based topical anaesthetics might be hard to justify, given the availability of other effective topical anaesthetics without cocaine. However, the overall quality of the evidence according to the GRADE system is low owing to limitations in design and implementation, imprecision of results and high probability of publication bias (selective reporting of data). Additional well-designed RCTs with low risk of bias are necessary before definitive conclusions can be reached.

Mediation analysis: a retrospective snapshot of practice and more recent directions.

PubMed

Gelfand, Lois A; Mensinger, Janell L; Tenhave, Thomas

2009-04-01

R. Baron and D. A. Kenny's (1986) paper introducing mediation analysis has been cited over 9,000 times, but concerns have been expressed about how this method is used. The authors review past and recent methodological literature and make recommendations for how to address 3 main issues: association, temporal order, and the no omitted variables assumption. The authors briefly visit the topics of reliability and the confirmatory-exploratory distinction. In addition, to provide a sense of the extent to which the earlier literature had been absorbed into practice, the authors examined a sample of 50 articles from 2002 citing R. Baron and D. A. Kenny and containing at least 1 mediation analysis via ordinary least squares regression. A substantial proportion of these articles included problematic reporting; as of 2002, there appeared to be room for improvement in conducting such mediation analyses. Future literature reviews will demonstrate the extent to which the situation has improved.

Reflections on the Journal of Applied Psychology for 2003 to 2008.

PubMed

Zedeck, Sheldon

2017-03-01

The topic and theme content of the articles published during my term as editor of the Journal of Applied Psychology (2003-2008) are presented and discussed. The analysis of the content and trends is discussed in the context of attempts by my editorial team to influence what content was to be considered for publication as well as to engage in special efforts to generate more "theory" as well as alternative methodological approaches (e.g., qualitative data, content analysis, and the like) into the journal. The bigger issue for the perspective is whether the editorial team can influence what is published (yes) as opposed to what is researched (unlikely). The bottom line of the analysis is a call for future research that takes an interdisciplinary or multidisciplinary approach to the study of applied problems in a work setting. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Defining competency-based evaluation objectives in family medicine

PubMed Central

Lawrence, Kathrine; Allen, Tim; Brailovsky, Carlos; Crichton, Tom; Bethune, Cheri; Donoff, Michel; Laughlin, Tom; Wetmore, Stephen; Carpentier, Marie-Pierre; Visser, Shaun

2011-01-01

Abstract Objective To develop key features for priority topics previously identified by the College of Family Physicians of Canada that, together with skill dimensions and phases of the clinical encounter, broadly describe competence in family medicine. Design Modified nominal group methodology, which was used to develop key features for each priority topic through an iterative process. Setting The College of Family Physicians of Canada. Participants An expert group of 7 family physicians and 1 educational consultant, all of whom had experience in assessing competence in family medicine. Group members represented the Canadian family medicine context with respect to region, sex, language, community type, and experience. Methods The group used a modified Delphi process to derive a detailed operational definition of competence, using multiple iterations until consensus was achieved for the items under discussion. The group met 3 to 4 times a year from 2000 to 2007. Main findings The group analyzed 99 topics and generated 773 key features. There were 2 to 20 (average 7.8) key features per topic; 63% of the key features focused on the diagnostic phase of the clinical encounter. Conclusion This project expands previous descriptions of the process of generating key features for assessment, and removes this process from the context of written examinations. A key-features analysis of topics focuses on higher-order cognitive processes of clinical competence. The project did not define all the skill dimensions of competence to the same degree, but it clearly identified those requiring further definition. This work generates part of a discipline-specific, competency-based definition of family medicine for assessment purposes. It limits the domain for assessment purposes, which is an advantage for the teaching and assessment of learners. A validation study on the content of this work would ensure that it truly reflects competence in family medicine. PMID:21998245

At the Leading Front of Neuroscience: A Bibliometric Study of the 100 Most-Cited Articles

PubMed Central

Yeung, Andy W. K.; Goto, Tazuko K.; Leung, W. Keung

2017-01-01

Background: It might be difficult for clinicians and scientists to identify comprehensively the major research topics given the large number of publications. A bibliometric report that identifies the most-cited articles within the body of the relevant literature may provide insight and guidance for readers toward scientific topics that are considered important for researchers and all relevant workers of academia. To our knowledge, there is a lack of an overall evaluation of the most-cited articles and hence of a comprehensive review of major research topics in neuroscience. The present study was therefore proposed to analyze and characterize the 100 most-cited articles in neuroscience. Methods: Based on data provided from Web of Science, the 100 most-cited articles relevant to neuroscience were identified and characterized. Information was extracted for each included article to assess for the publication year, journal published, impact factor, adjusted impact factor, citation count (total, normalized, and adjusted), reference list, authorship and article type. Results: The total citation count for the 100 most-cited articles ranged from 7,326 to 2,138 (mean 3087.0) and the normalized citation count ranged from 0.163 to 0.007 (mean 0.054). The majority of the 100 articles were research articles (67%) and published from 1996 to 2000 (30%). The author and journal with the largest share of these 100 articles were Stephen M. Smith (n = 6) and Science (n = 13) respectively. Among the 100 most-cited articles, 37 were interlinked via citations of one another, and they could be classified into five major topics, four of which were scientific topics, namely neurological disorders, prefrontal cortex/emotion/reward, brain network, and brain mapping. The remaining topic was methodology. Interestingly 41 out of 63 of the rest, non-interlinked articles could also be categorized under the above five topics. Adjusted journal impact factor among these 100 articles did not appear to be associated with the corresponding adjusted citation count. Conclusion: The current study compiles a comprehensive list and analysis of the 100 most-cited articles relevant to neuroscience that enables the comprehensive identification and recognition of the most important and relevant research topics concerned. PMID:28785211

At the Leading Front of Neuroscience: A Bibliometric Study of the 100 Most-Cited Articles.

PubMed

Yeung, Andy W K; Goto, Tazuko K; Leung, W Keung

2017-01-01

Background: It might be difficult for clinicians and scientists to identify comprehensively the major research topics given the large number of publications. A bibliometric report that identifies the most-cited articles within the body of the relevant literature may provide insight and guidance for readers toward scientific topics that are considered important for researchers and all relevant workers of academia. To our knowledge, there is a lack of an overall evaluation of the most-cited articles and hence of a comprehensive review of major research topics in neuroscience. The present study was therefore proposed to analyze and characterize the 100 most-cited articles in neuroscience. Methods: Based on data provided from Web of Science, the 100 most-cited articles relevant to neuroscience were identified and characterized. Information was extracted for each included article to assess for the publication year, journal published, impact factor, adjusted impact factor, citation count (total, normalized, and adjusted), reference list, authorship and article type. Results: The total citation count for the 100 most-cited articles ranged from 7,326 to 2,138 (mean 3087.0) and the normalized citation count ranged from 0.163 to 0.007 (mean 0.054). The majority of the 100 articles were research articles (67%) and published from 1996 to 2000 (30%). The author and journal with the largest share of these 100 articles were Stephen M. Smith ( n = 6) and Science ( n = 13) respectively. Among the 100 most-cited articles, 37 were interlinked via citations of one another, and they could be classified into five major topics, four of which were scientific topics, namely neurological disorders, prefrontal cortex/emotion/reward, brain network, and brain mapping. The remaining topic was methodology. Interestingly 41 out of 63 of the rest, non-interlinked articles could also be categorized under the above five topics. Adjusted journal impact factor among these 100 articles did not appear to be associated with the corresponding adjusted citation count. Conclusion: The current study compiles a comprehensive list and analysis of the 100 most-cited articles relevant to neuroscience that enables the comprehensive identification and recognition of the most important and relevant research topics concerned.

How to conduct a high-quality original study on a diagnostic research topic.

PubMed

Yao, Xiaomei; Vella, Emily

2017-09-01

As health research methodologists and journal reviewers, we noticed that the methodological rigor of many publications on diagnostic or prognostic topics in the medical literature could be improved. We present a concise and clear series of reviews to help clinicians and health researchers to master the basic key components of how to conduct a high-quality original study or systematic review on a diagnostic or prognostic research topic from a methodological perspective. This is the first review of the series, which focuses on how to conduct a high-quality diagnostic study. We are introducing four aspects: clarifying the objectives; generating an appropriate research question; planning the study design; and reporting and analyzing data. This review highlights that diagnostic test accuracy outcomes are surrogates for patient outcomes, a diagnostic test has three roles, the "PIRO" components should be included in a diagnostic research question, a new study should be registered, multiple index tests can be compared in one study, and prevalence affects test accuracy outcomes. This review also emphasizes reporting any thresholds, calculating sample size, and performing a two-by-three table to calculate diagnostic outcomes. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Application of Failure Modes and Effects Analysis Methodology to Intrathecal Drug Delivery for Pain Management

PubMed Central

Patel, Teresa; Fisher, Stanley P.

2016-01-01

Objective This study aimed to utilize failure modes and effects analysis (FMEA) to transform clinical insights into a risk mitigation plan for intrathecal (IT) drug delivery in pain management. Methods The FMEA methodology, which has been used for quality improvement, was adapted to assess risks (i.e., failure modes) associated with IT therapy. Ten experienced pain physicians scored 37 failure modes in the following categories: patient selection for therapy initiation (efficacy and safety concerns), patient safety during IT therapy, and product selection for IT therapy. Participants assigned severity, probability, and detection scores for each failure mode, from which a risk priority number (RPN) was calculated. Failure modes with the highest RPNs (i.e., most problematic) were discussed, and strategies were proposed to mitigate risks. Results Strategic discussions focused on 17 failure modes with the most severe outcomes, the highest probabilities of occurrence, and the most challenging detection. The topic of the highest‐ranked failure mode (RPN = 144) was manufactured monotherapy versus compounded combination products. Addressing failure modes associated with appropriate patient and product selection was predicted to be clinically important for the success of IT therapy. Conclusions The methodology of FMEA offers a systematic approach to prioritizing risks in a complex environment such as IT therapy. Unmet needs and information gaps are highlighted through the process. Risk mitigation and strategic planning to prevent and manage critical failure modes can contribute to therapeutic success. PMID:27477689

Generic Degraded Congiguration Probability Analysis for DOE Codisposal Waste Package

DOE Office of Scientific and Technical Information (OSTI.GOV)

S.F.A. Deng; M. Saglam; L.J. Gratton

2001-05-23

In accordance with the technical work plan, ''Technical Work Plan For: Department of Energy Spent Nuclear Fuel Work Packages'' (CRWMS M&O 2000c), this Analysis/Model Report (AMR) is developed for the purpose of screening out degraded configurations for U.S. Department of Energy (DOE) spent nuclear fuel (SNF) types. It performs the degraded configuration parameter and probability evaluations of the overall methodology specified in the ''Disposal Criticality Analysis Methodology Topical Report'' (YMP 2000, Section 3) to qualifying configurations. Degradation analyses are performed to assess realizable parameter ranges and physical regimes for configurations. Probability calculations are then performed for configurations characterized by k{submore » eff} in excess of the Critical Limit (CL). The scope of this document is to develop a generic set of screening criteria or models to screen out degraded configurations having potential for exceeding a criticality limit. The developed screening criteria include arguments based on physical/chemical processes and probability calculations and apply to DOE SNF types when codisposed with the high-level waste (HLW) glass inside a waste package. The degradation takes place inside the waste package and is long after repository licensing has expired. The emphasis of this AMR is on degraded configuration screening and the probability analysis is one of the approaches used for screening. The intended use of the model is to apply the developed screening criteria to each DOE SNF type following the completion of the degraded mode criticality analysis internal to the waste package.« less

77 FR 18823 - Solicitation for Nominations for Members of the U.S. Preventive Services Task Force (USPSTF)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-28

... without primary health care clinical experience may be selected based on their expertise in methodological... calls and via email discussions. Member duties include prioritizing topics, designing research plans...

"The Need to Know": 1994 Senior Researcher Award Acceptance Address.

ERIC Educational Resources Information Center

Carlsen, James C.

1994-01-01

Discusses issues related to music education research. Presents three criteria to guide selection of research topics. Concludes that the challenge for music researchers is to avoid research that merely supports a "favored" methodology. (ACM)

SociAL Sensor Analytics: Measuring Phenomenology at Scale

DOE Office of Scientific and Technical Information (OSTI.GOV)

Corley, Courtney D.; Dowling, Chase P.; Rose, Stuart J.

The objective of this paper is to present a system for interrogating immense social media streams through analytical methodologies that characterize topics and events critical to tactical and strategic planning. First, we propose a conceptual framework for interpreting social media as a sensor network. Time-series models and topic clustering algorithms are used to implement this concept into a functioning analytical system. Next, we address two scientific challenges: 1) to understand, quantify, and baseline phenomenology of social media at scale, and 2) to develop analytical methodologies to detect and investigate events of interest. This paper then documents computational methods and reportsmore » experimental findings that address these challenges. Ultimately, the ability to process billions of social media posts per week over a period of years enables the identification of patterns and predictors of tactical and strategic concerns at an unprecedented rate through SociAL Sensor Analytics (SALSA).« less

A Three-Dimensional Approach and Open Source Structure for the Design and Experimentation of Teaching-Learning Sequences: The case of friction

NASA Astrophysics Data System (ADS)

Besson, Ugo; Borghi, Lidia; De Ambrosis, Anna; Mascheretti, Paolo

2010-07-01

We have developed a teaching-learning sequence (TLS) on friction based on a preliminary study involving three dimensions: an analysis of didactic research on the topic, an overview of usual approaches, and a critical analysis of the subject, considered also in its historical development. We found that mostly the usual presentations do not take into account the complexity of friction as it emerges from scientific research, may reinforce some inaccurate students' conceptions, and favour a limited vision of friction phenomena. The TLS we propose begins by considering a wide range of friction phenomena to favour an initial motivation and a broader view of the topic and then develops a path of interrelated observations, experiments, and theoretical aspects. It proposes the use of structural models, involving visual representations and stimulating intuition, aimed at helping students build mental models of friction mechanisms. To facilitate the reproducibility in school contexts, the sequence is designed as an open source structure, with a core of contents, conceptual correlations and methodological choices, and a cloud of elements that can be re-designed by teachers. The sequence has been tested in teacher education and in upper secondary school, and has shown positive results in overcoming student difficulties and stimulating richer reasoning based on the structural models we suggested. The proposed path has modified the teachers' view of the topic, producing a motivation to change their traditional presentations. The open structure of the sequence has facilitated its implementation by teachers in school in coherence with the rationale of the proposal.

Current Topics in Epilepsy Surgery.

PubMed

Usui, Naotaka

2016-05-15

This article reviews the current topics in the field of epilepsy surgery. Each type of epilepsy is associated with a different set of questions and goals. In mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS), postoperative seizure outcome is satisfactory. A recent meta-analysis revealed superior seizure outcome after anterior temporal lobectomy compared with selective amygdalohippocampectomy; in terms of cognitive outcome; however, amygdalohippocampectomy may be beneficial. In temporal lobe epilepsy with normal magnetic resonance imaging (MRI), postoperative seizure outcome is not as favorable as it is in MTLE with HS; further improvement of seizure outcome in these cases is necessary. Focal cortical dysplasia is the most common substrate in intractable neocortical epilepsy, especially in children, as well as in MRI-invisible neocortical epilepsy. Postoperative seizure-free outcome is approximately 60-70%; further diagnostic and therapeutic improvement is required. Regarding diagnostic methodology, an important topic currently under discussion is wideband electroencephalogram (EEG) analysis. Although high-frequency oscillations and ictal direct current shifts are considered important markers of epileptogenic zones, the clinical significance of these findings should be clarified further. Regarding alternatives to surgery, neuromodulation therapy can be an option for patients who are not amenable to resective surgery. In addition to vagus nerve stimulation, intracranial stimulation such as responsive neurostimulation or anterior thalamic stimulation is reported to have a modest seizure suppression effect. Postoperative management such as rehabilitation and antiepileptic drug (AED) management is important. It has been reported that postoperative rehabilitation improves postoperative employment status. Pre- and post-operative comprehensive care is mandatory for postoperative improvement of quality of life.

Skin penetration and antioxidant effect of cosmeto-textiles with gallic acid.

PubMed

Alonso, C; Martí, M; Barba, C; Lis, M; Rubio, L; Coderch, L

2016-03-01

In this work, the antioxidant gallic acid (GA) has been encapsulated in microspheres prepared with poly-ε-caprolactone (PCL) and incorporated into polyamide (PA) obtaining the cosmeto-textile. The topical application of the cosmeto-textile provides a reservoir effect in the skin delivery of GA. The close contact of the cosmeto-textile, containing microsphere-encapsulated GA (ME-GA), with the skin and their corresponding occlusion, may be the main reasons that explain the crossing of active principle (GA) through the skin barrier, located in the stratum corneum, and its penetration into the different compartments of the skin, epidermis and dermis. An ex vivo assessment was performed to evaluate the antioxidant effect of the ME-GA on the stratum corneum (SC) using the thiobarbituric acid-reactive species (TBARS) test. The test is based on a non-invasive ex vivo methodology that evaluates lipid peroxides formed in the outermost layers of the SC from human volunteers after UV radiation to determine the effectiveness of an antioxidant. In this case, a ME-GA cosmeto-textile or ME-GA formulation were applied to the skin in vivo and lipid peroxidation (LPO) in the horny layer were determined after UV irradiation. This methodology may be used as a quality control tool to determine ex vivo the percentage of LPO inhibition on human SC for a variety of antioxidants that are topically applied, in this case GA. Results show that LPO formation was inhibited in human SC when GA was applied directly or embedded in the cosmeto-textile, demonstrating the effectiveness of both applications. The percentage of LPO inhibition obtained after both topical applications was approximately 10% for the cosmeto-textile and 41% for the direct application of microspheres containing GA. This methodology could be used to determine the effectiveness of topically applied antioxidants encapsulated in cosmeto-textiles on human SC. Copyright © 2016 Elsevier B.V. All rights reserved.

The Teaching Effectiveness of a Relevant Physics Course

NASA Astrophysics Data System (ADS)

Hobson, Art

1998-04-01

If America is to achieve the science literacy that is ssential to industrialized democracy, all students must study such topics as scientific methodology, pseudoscience, critical thinking, ozone depletion, technological risk, and global warming. My large-enrollment liberal-arts physics course covers the great principles of physics along with several such philosophical and societal topics. Students find these topics relevant and fascinating, leading to strong course evaluations and large enrollments by non-scientists even in courses labeled physics. I will describe this course and present some evidence indicating that the course is effective in communicating physics and its interdisciplinary connections. A textbook, Physics: Concepts and Connections (Prentice Hall, 1995, 2nd edition to appear in June 1998), is available.

Psychology and Aging: The First 20 Years

PubMed Central

Zacks, Rose T.; Blanchard-Fields, Fredda; Haley, William E.

2006-01-01

This article provides a review of the first 20 years of Psychology and Aging, the American Psychological Association’s first and only scholarly journal devoted to the topic of aging. The authors briefly summarize its history, its contributions to the study of aging, and its broader status as a scholarly publication. One theme highlighted in our review is the diversity of content in the journal throughout its history. Another is the strong impact that articles published in the journal have had on both basic and applied topics in aging. Efforts to encompass the breadth of topics and methodologies in aging research while retaining excellent quality remain the exciting but essential challenge for Psychology and Aging. PMID:16594786

Summarizing an Ontology: A "Big Knowledge" Coverage Approach.

PubMed

Zheng, Ling; Perl, Yehoshua; Elhanan, Gai; Ochs, Christopher; Geller, James; Halper, Michael

2017-01-01

Maintenance and use of a large ontology, consisting of thousands of knowledge assertions, are hampered by its scope and complexity. It is important to provide tools for summarization of ontology content in order to facilitate user "big picture" comprehension. We present a parameterized methodology for the semi-automatic summarization of major topics in an ontology, based on a compact summary of the ontology, called an "aggregate partial-area taxonomy", followed by manual enhancement. An experiment is presented to test the effectiveness of such summarization measured by coverage of a given list of major topics of the corresponding application domain. SNOMED CT's Specimen hierarchy is the test-bed. A domain-expert provided a list of topics that serves as a gold standard. The enhanced results show that the aggregate taxonomy covers most of the domain's main topics.

VIII. THE PAST, PRESENT, AND FUTURE OF DEVELOPMENTAL METHODOLOGY.

PubMed

Little, Todd D; Wang, Eugene W; Gorrall, Britt K

2017-06-01

This chapter selectively reviews the evolution of quantitative practices in the field of developmental methodology. The chapter begins with an overview of the past in developmental methodology, discussing the implementation and dissemination of latent variable modeling and, in particular, longitudinal structural equation modeling. It then turns to the present state of developmental methodology, highlighting current methodological advances in the field. Additionally, this section summarizes ample quantitative resources, ranging from key quantitative methods journal articles to the various quantitative methods training programs and institutes. The chapter concludes with the future of developmental methodology and puts forth seven future innovations in the field. The innovations discussed span the topics of measurement, modeling, temporal design, and planned missing data designs. Lastly, the chapter closes with a brief overview of advanced modeling techniques such as continuous time models, state space models, and the application of Bayesian estimation in the field of developmental methodology. © 2017 The Society for Research in Child Development, Inc.

Conducting high-value secondary dataset analysis: an introductory guide and resources.

PubMed

Smith, Alexander K; Ayanian, John Z; Covinsky, Kenneth E; Landon, Bruce E; McCarthy, Ellen P; Wee, Christina C; Steinman, Michael A

2011-08-01

Secondary analyses of large datasets provide a mechanism for researchers to address high impact questions that would otherwise be prohibitively expensive and time-consuming to study. This paper presents a guide to assist investigators interested in conducting secondary data analysis, including advice on the process of successful secondary data analysis as well as a brief summary of high-value datasets and online resources for researchers, including the SGIM dataset compendium ( www.sgim.org/go/datasets ). The same basic research principles that apply to primary data analysis apply to secondary data analysis, including the development of a clear and clinically relevant research question, study sample, appropriate measures, and a thoughtful analytic approach. A real-world case description illustrates key steps: (1) define your research topic and question; (2) select a dataset; (3) get to know your dataset; and (4) structure your analysis and presentation of findings in a way that is clinically meaningful. Secondary dataset analysis is a well-established methodology. Secondary analysis is particularly valuable for junior investigators, who have limited time and resources to demonstrate expertise and productivity.

New Perspectives on Assessing Amplification Effects

PubMed Central

Souza, Pamela E.; Tremblay, Kelly L.

2006-01-01

Clinicians have long been aware of the range of performance variability with hearing aids. Despite improvements in technology, there remain many instances of well-selected and appropriately fitted hearing aids whereby the user reports minimal improvement in speech understanding. This review presents a multistage framework for understanding how a hearing aid affects performance. Six stages are considered: (1) acoustic content of the signal, (2) modification of the signal by the hearing aid, (3) interaction between sound at the output of the hearing aid and the listener's ear, (4) integrity of the auditory system, (5) coding of available acoustic cues by the listener's auditory system, and (6) correct identification of the speech sound. Within this framework, this review describes methodology and research on 2 new assessment techniques: acoustic analysis of speech measured at the output of the hearing aid and auditory evoked potentials recorded while the listener wears hearing aids. Acoustic analysis topics include the relationship between conventional probe microphone tests and probe microphone measurements using speech, appropriate procedures for such tests, and assessment of signal-processing effects on speech acoustics and recognition. Auditory evoked potential topics include an overview of physiologic measures of speech processing and the effect of hearing loss and hearing aids on cortical auditory evoked potential measurements in response to speech. Finally, the clinical utility of these procedures is discussed. PMID:16959734

A scoping review of scoping reviews: advancing the approach and enhancing the consistency.

PubMed

Pham, Mai T; Rajić, Andrijana; Greig, Judy D; Sargeant, Jan M; Papadopoulos, Andrew; McEwen, Scott A

2014-12-01

The scoping review has become an increasingly popular approach for synthesizing research evidence. It is a relatively new approach for which a universal study definition or definitive procedure has not been established. The purpose of this scoping review was to provide an overview of scoping reviews in the literature. A scoping review was conducted using the Arksey and O'Malley framework. A search was conducted in four bibliographic databases and the gray literature to identify scoping review studies. Review selection and characterization were performed by two independent reviewers using pretested forms. The search identified 344 scoping reviews published from 1999 to October 2012. The reviews varied in terms of purpose, methodology, and detail of reporting. Nearly three-quarter of reviews (74.1%) addressed a health topic. Study completion times varied from 2 weeks to 20 months, and 51% utilized a published methodological framework. Quality assessment of included studies was infrequently performed (22.38%). Scoping reviews are a relatively new but increasingly common approach for mapping broad topics. Because of variability in their conduct, there is a need for their methodological standardization to ensure the utility and strength of evidence. © 2014 The Authors. Research Synthesis Methods published by John Wiley & Sons, Ltd.

Twitter-Based Detection of Illegal Online Sale of Prescription Opioid.

PubMed

Mackey, Tim K; Kalyanam, Janani; Katsuki, Takeo; Lanckriet, Gert

2017-12-01

To deploy a methodology accurately identifying tweets marketing the illegal online sale of controlled substances. We first collected tweets from the Twitter public application program interface stream filtered for prescription opioid keywords. We then used unsupervised machine learning (specifically, topic modeling) to identify topics associated with illegal online marketing and sales. Finally, we conducted Web forensic analyses to characterize different types of online vendors. We analyzed 619 937 tweets containing the keywords codeine, Percocet, fentanyl, Vicodin, Oxycontin, oxycodone, and hydrocodone over a 5-month period from June to November 2015. A total of 1778 tweets (< 1%) were identified as marketing the sale of controlled substances online; 90% had imbedded hyperlinks, but only 46 were "live" at the time of the evaluation. Seven distinct URLs linked to Web sites marketing or illegally selling controlled substances online. Our methodology can identify illegal online sale of prescription opioids from large volumes of tweets. Our results indicate that controlled substances are trafficked online via different strategies and vendors. Public Health Implications. Our methodology can be used to identify illegal online sellers in criminal violation of the Ryan Haight Online Pharmacy Consumer Protection Act.

On the fit of models to covariances and methodology to the Bulletin.

PubMed

Bentler, P M

1992-11-01

It is noted that 7 of the 10 top-cited articles in the Psychological Bulletin deal with methodological topics. One of these is the Bentler-Bonett (1980) article on the assessment of fit in covariance structure models. Some context is provided on the popularity of this article. In addition, a citation study of methodology articles appearing in the Bulletin since 1978 was carried out. It verified that publications in design, evaluation, measurement, and statistics continue to be important to psychological research. Some thoughts are offered on the role of the journal in making developments in these areas more accessible to psychologists.

Synthesis of finite displacements and displacements in continental margins

NASA Technical Reports Server (NTRS)

Speed, R. C.; Elison, M. W.; Heck, F. R.; Russo, R. M.

1988-01-01

The scope of the project is the analysis of displacement-rate fields in the transitional regions between cratonal and oceanic lithospheres over Phanerozoic time (last 700 ma). Associated goals are an improved understanding of range of widths of major displacement zones; the partition of displacement gradients and rotations with position and depth in such zones; the temporal characteristics of such zones-the steadiness, episodicity, and duration of uniform versus nonunifrom fields; and the mechanisms and controls of the establishment and kinematics of displacement zones. The objective is to provide a context of time-averaged kinematics of displacement zones. The initial phase is divided topically among the methodology of measurement and reduction of displacements in the lithosphere and the preliminary analysis from geologic and other data of actual displacement histories from the Cordillera, Appalachians, and southern North America.

Methodological issues in studies of air pollution and reproductive health.

PubMed

Woodruff, Tracey J; Parker, Jennifer D; Darrow, Lyndsey A; Slama, Rémy; Bell, Michelle L; Choi, Hyunok; Glinianaia, Svetlana; Hoggatt, Katherine J; Karr, Catherine J; Lobdell, Danelle T; Wilhelm, Michelle

2009-04-01

In the past decade there have been an increasing number of scientific studies describing possible effects of air pollution on perinatal health. These papers have mostly focused on commonly monitored air pollutants, primarily ozone (O(3)), particulate matter (PM), sulfur dioxide (SO(2)), carbon monoxide (CO), and nitrogen dioxide (NO(2)), and various indices of perinatal health, including fetal growth, pregnancy duration, and infant mortality. While most published studies have found some marker of air pollution related to some types of perinatal outcomes, variability exists in the nature of the pollutants and outcomes associated. Synthesis of the findings has been difficult for various reasons, including differences in study design and analysis. A workshop was held in September 2007 to discuss methodological differences in the published studies as a basis for understanding differences in study findings and to identify priorities for future research, including novel approaches for existing data. Four broad topic areas were considered: confounding and effect modification, spatial and temporal exposure variations, vulnerable windows of exposure, and multiple pollutants. Here we present a synopsis of the methodological issues and challenges in each area and make recommendations for future study. Two key recommendations include: (1) parallel analyses of existing data sets using a standardized methodological approach to disentangle true differences in associations from methodological differences among studies; and (2) identification of animal studies to inform important mechanistic research gaps. This work is of critical public health importance because of widespread exposure and because perinatal outcomes are important markers of future child and adult health.

Recent approaches for enhancing sensitivity in enantioseparations by CE.

PubMed

Sánchez-Hernández, Laura; García-Ruiz, Carmen; Luisa Marina, María; Luis Crego, Antonio

2010-01-01

This article reviews the latest methodological and instrumental improvements for enhancing sensitivity in chiral analysis by CE. The review covers literature from March 2007 until May 2009, that is, the works published after the appearance of the latest review article on the same topic by Sánchez-Hernández et al. [Electrophoresis 2008, 29, 237-251]. Off-line and on-line sample treatment techniques, on-line sample preconcentration strategies based on electrophoretic and chromatographic principles, and alternative detection systems to the widely employed UV/Vis detection in CE are the most relevant approaches discussed for improving sensitivity. Microchip technologies are also included since they can open up great possibilities to achieve sensitive and fast enantiomeric separations.

Does spatial attention modulate the C1 component? The jury continues to deliberate.

PubMed

Baumgartner, Hannah M; Graulty, Christian J; Hillyard, Steven A; Pitts, Michael A

The thoughful comments on our study (Baumgartner et al., this issue) that failed to replicate the C1 attention effect reported by a previous study roughly fall into three broad categories. First, the commentators identified specific differences between the two studies that may have contributed to the discrepant results. Second, they highlighted some of the theoretical and methodological problems that are encountered when trying to demonstrate attention effects on the initial evoked response in primary visual cortex. Third, they offered a number of proposals for optimizing experimental designs and analysis methods that may increase the likelihood of observing attention-related modulations of the C1. We consider each of these topics in turn.

Methodology: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement.

PubMed

Ornelas, Joe; Dichter, Jeffrey R; Devereaux, Asha V; Kissoon, Niranjan; Livinski, Alicia; Christian, Michael D

2014-10-01

Natural disasters, industrial accidents, terrorism attacks, and pandemics all have the capacity to result in large numbers of critically ill or injured patients. This supplement provides suggestions for all those involved in a disaster or pandemic with multiple critically ill patients, including front-line clinicians, hospital administrators, professional societies, and public health or government officials. The field of disaster medicine does not have the required body of evidence needed to undergo a traditional guideline development process. In result, consensus statement-development methodology was used to capture the highest-caliber expert opinion in a structured, scientific approach. Task Force Executive Committee members identified core topic areas regarding the provision of care to critically ill or injured patients from pandemics or disasters and subsequently assembled an international panel for each identified area. International disaster medicine experts were brought together to identify key questions (in a population, intervention, comparator, outcome [PICO]-based format) within each of the core topic areas. Comprehensive literature searches were then conducted to identify studies upon which evidence-based recommendations could be made. No studies of sufficient quality were identified. Therefore, the panel developed expert opinion-based suggestions that are presented in this supplement using a modified Delphi process. A total of 315 suggestions were drafted across all topic groups. After two rounds of a Delphi consensus-development process, 267 suggestions were chosen by the panel to include in the document and published in a total of 12 manuscripts composing the core chapters of this supplement. Draft manuscripts were prepared by the topic editor and members of the working groups for each of the topics, producing a total of 11 papers. Once the preliminary drafts were received, the Executive Committee (Writing Committee) then met to review, edit, and promote alignment of all of the primary drafts of the manuscripts prepared by the topic editors and their groups. The topic editors then revised their manuscripts based on the Executive Committee's edits and comments. The Writing Committee subsequently reviewed the updated drafts and prepared the final manuscripts for submission to the Guidelines Oversight Committee (GOC). The manuscripts subsequently underwent review by the GOC, including external review as well as peer review for the journal publication. The Writing Committee received the feedback from the reviewers and modified the manuscripts as required. Based on a robust and transparent process, this project used rigorous methodology to produce clinically relevant, trustworthy consensus statements, with the aim to provide needed guidance on treatment and procedures for practitioners, hospital administrators, and public health and government officials when addressing the care of critically ill or injured patients in disasters or pandemics.

Assessment of online public opinions on large infrastructure projects: A case study of the Three Gorges Project in China

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang, Hanchen, E-mail: jhc13@mails.tsinghua.edu.cn; Qiang, Maoshan, E-mail: qiangms@tsinghua.edu.cn; Lin, Peng, E-mail: celinpe@mail.tsinghua.edu.cn

Public opinion becomes increasingly salient in the ex post evaluation stage of large infrastructure projects which have significant impacts to the environment and the society. However, traditional survey methods are inefficient in collection and assessment of the public opinion due to its large quantity and diversity. Recently, Social media platforms provide a rich data source for monitoring and assessing the public opinion on controversial infrastructure projects. This paper proposes an assessment framework to transform unstructured online public opinions on large infrastructure projects into sentimental and topical indicators for enhancing practices of ex post evaluation and public participation. The framework usesmore » web crawlers to collect online comments related to a large infrastructure project and employs two natural language processing technologies, including sentiment analysis and topic modeling, with spatio-temporal analysis, to transform these comments into indicators for assessing online public opinion on the project. Based on the framework, we investigate the online public opinion of the Three Gorges Project on China's largest microblogging site, namely, Weibo. Assessment results present spatial-temporal distributions of post intensity and sentiment polarity, reveals major topics with different sentiments and summarizes managerial implications, for ex post evaluation of the world's largest hydropower project. The proposed assessment framework is expected to be widely applied as a methodological strategy to assess public opinion in the ex post evaluation stage of large infrastructure projects. - Highlights: • We developed a framework to assess online public opinion on large infrastructure projects with environmental impacts. • Indicators were built to assess post intensity, sentiment polarity and major topics of the public opinion. • We took the Three Gorges Project (TGP) as an example to demonstrate the effectiveness proposed framework. • We revealed spatial-temporal patterns of post intensity and sentiment polarity on the TGP. • We drew implications for a more in-depth understanding of the public opinion on large infrastructure projects.« less

[Parents and teachers perception of the risky factors for legal or illegal drugs consumption among students].

PubMed

Sánchez, Fátima Morán; Ferriani, Maria das Graças Carvalho

2004-01-01

This work had the opportunity to know and analyze the parents and teachers' perception about the risky factors that influence in scholars for the legal and illegal consumption of drugs. The methodology focused is the qualitative one, of the descriptive explanatory type with the modality of case study. The sample consisted on 8 parents and 8 teachers from the 5th, 6th and 7th basic grades of the Fiscal Primary School, "Carmen Navarro Wither" from Guayaquil, Ecuador. To obtain the data, it was used the "focused group technique" and the observation participation. Also, the thematic containing analysis was done. During the develop of the focused group, it was showed by the parents and teachers a lot of interest and preoccupation about the topic and they perceived it as risky factors the following: The economic situation that commonly force the parents' emigration, the influence of the surroundings and the ignorance of parents and teachers about the drugs topic. Besides, they really would like to know and learn more the drugs' consumption prevention to raise, in this way, the children's rejection about it.

Cosmology and fundamental physics with the Euclid satellite.

PubMed

Amendola, Luca; Appleby, Stephen; Avgoustidis, Anastasios; Bacon, David; Baker, Tessa; Baldi, Marco; Bartolo, Nicola; Blanchard, Alain; Bonvin, Camille; Borgani, Stefano; Branchini, Enzo; Burrage, Clare; Camera, Stefano; Carbone, Carmelita; Casarini, Luciano; Cropper, Mark; de Rham, Claudia; Dietrich, Jörg P; Di Porto, Cinzia; Durrer, Ruth; Ealet, Anne; Ferreira, Pedro G; Finelli, Fabio; García-Bellido, Juan; Giannantonio, Tommaso; Guzzo, Luigi; Heavens, Alan; Heisenberg, Lavinia; Heymans, Catherine; Hoekstra, Henk; Hollenstein, Lukas; Holmes, Rory; Hwang, Zhiqi; Jahnke, Knud; Kitching, Thomas D; Koivisto, Tomi; Kunz, Martin; La Vacca, Giuseppe; Linder, Eric; March, Marisa; Marra, Valerio; Martins, Carlos; Majerotto, Elisabetta; Markovic, Dida; Marsh, David; Marulli, Federico; Massey, Richard; Mellier, Yannick; Montanari, Francesco; Mota, David F; Nunes, Nelson J; Percival, Will; Pettorino, Valeria; Porciani, Cristiano; Quercellini, Claudia; Read, Justin; Rinaldi, Massimiliano; Sapone, Domenico; Sawicki, Ignacy; Scaramella, Roberto; Skordis, Constantinos; Simpson, Fergus; Taylor, Andy; Thomas, Shaun; Trotta, Roberto; Verde, Licia; Vernizzi, Filippo; Vollmer, Adrian; Wang, Yun; Weller, Jochen; Zlosnik, Tom

2018-01-01

Euclid is a European Space Agency medium-class mission selected for launch in 2020 within the cosmic vision 2015-2025 program. The main goal of Euclid is to understand the origin of the accelerated expansion of the universe. Euclid will explore the expansion history of the universe and the evolution of cosmic structures by measuring shapes and red-shifts of galaxies as well as the distribution of clusters of galaxies over a large fraction of the sky. Although the main driver for Euclid is the nature of dark energy, Euclid science covers a vast range of topics, from cosmology to galaxy evolution to planetary research. In this review we focus on cosmology and fundamental physics, with a strong emphasis on science beyond the current standard models. We discuss five broad topics: dark energy and modified gravity, dark matter, initial conditions, basic assumptions and questions of methodology in the data analysis. This review has been planned and carried out within Euclid's Theory Working Group and is meant to provide a guide to the scientific themes that will underlie the activity of the group during the preparation of the Euclid mission.

Cosmology and fundamental physics with the Euclid satellite

NASA Astrophysics Data System (ADS)

Amendola, Luca; Appleby, Stephen; Avgoustidis, Anastasios; Bacon, David; Baker, Tessa; Baldi, Marco; Bartolo, Nicola; Blanchard, Alain; Bonvin, Camille; Borgani, Stefano; Branchini, Enzo; Burrage, Clare; Camera, Stefano; Carbone, Carmelita; Casarini, Luciano; Cropper, Mark; de Rham, Claudia; Dietrich, Jörg P.; Di Porto, Cinzia; Durrer, Ruth; Ealet, Anne; Ferreira, Pedro G.; Finelli, Fabio; García-Bellido, Juan; Giannantonio, Tommaso; Guzzo, Luigi; Heavens, Alan; Heisenberg, Lavinia; Heymans, Catherine; Hoekstra, Henk; Hollenstein, Lukas; Holmes, Rory; Hwang, Zhiqi; Jahnke, Knud; Kitching, Thomas D.; Koivisto, Tomi; Kunz, Martin; La Vacca, Giuseppe; Linder, Eric; March, Marisa; Marra, Valerio; Martins, Carlos; Majerotto, Elisabetta; Markovic, Dida; Marsh, David; Marulli, Federico; Massey, Richard; Mellier, Yannick; Montanari, Francesco; Mota, David F.; Nunes, Nelson J.; Percival, Will; Pettorino, Valeria; Porciani, Cristiano; Quercellini, Claudia; Read, Justin; Rinaldi, Massimiliano; Sapone, Domenico; Sawicki, Ignacy; Scaramella, Roberto; Skordis, Constantinos; Simpson, Fergus; Taylor, Andy; Thomas, Shaun; Trotta, Roberto; Verde, Licia; Vernizzi, Filippo; Vollmer, Adrian; Wang, Yun; Weller, Jochen; Zlosnik, Tom

2018-04-01

Euclid is a European Space Agency medium-class mission selected for launch in 2020 within the cosmic vision 2015-2025 program. The main goal of Euclid is to understand the origin of the accelerated expansion of the universe. Euclid will explore the expansion history of the universe and the evolution of cosmic structures by measuring shapes and red-shifts of galaxies as well as the distribution of clusters of galaxies over a large fraction of the sky. Although the main driver for Euclid is the nature of dark energy, Euclid science covers a vast range of topics, from cosmology to galaxy evolution to planetary research. In this review we focus on cosmology and fundamental physics, with a strong emphasis on science beyond the current standard models. We discuss five broad topics: dark energy and modified gravity, dark matter, initial conditions, basic assumptions and questions of methodology in the data analysis. This review has been planned and carried out within Euclid's Theory Working Group and is meant to provide a guide to the scientific themes that will underlie the activity of the group during the preparation of the Euclid mission.

Cosmology and Fundamental Physics with the Euclid Satellite.

PubMed

Amendola, Luca; Appleby, Stephen; Bacon, David; Baker, Tessa; Baldi, Marco; Bartolo, Nicola; Blanchard, Alain; Bonvin, Camille; Borgani, Stefano; Branchini, Enzo; Burrage, Clare; Camera, Stefano; Carbone, Carmelita; Casarini, Luciano; Cropper, Mark; de Rham, Claudia; Di Porto, Cinzia; Ealet, Anne; Ferreira, Pedro G; Finelli, Fabio; García-Bellido, Juan; Giannantonio, Tommaso; Guzzo, Luigi; Heavens, Alan; Heisenberg, Lavinia; Heymans, Catherine; Hoekstra, Henk; Hollenstein, Lukas; Holmes, Rory; Horst, Ole; Jahnke, Knud; Kitching, Thomas D; Koivisto, Tomi; Kunz, Martin; La Vacca, Giuseppe; March, Marisa; Majerotto, Elisabetta; Markovic, Katarina; Marsh, David; Marulli, Federico; Massey, Richard; Mellier, Yannick; Mota, David F; Nunes, Nelson J; Percival, Will; Pettorino, Valeria; Porciani, Cristiano; Quercellini, Claudia; Read, Justin; Rinaldi, Massimiliano; Sapone, Domenico; Scaramella, Roberto; Skordis, Constantinos; Simpson, Fergus; Taylor, Andy; Thomas, Shaun; Trotta, Roberto; Verde, Licia; Vernizzi, Filippo; Vollmer, Adrian; Wang, Yun; Weller, Jochen; Zlosnik, Tom

2013-01-01

Euclid is a European Space Agency medium-class mission selected for launch in 2019 within the Cosmic Vision 2015-2025 program. The main goal of Euclid is to understand the origin of the accelerated expansion of the universe. Euclid will explore the expansion history of the universe and the evolution of cosmic structures by measuring shapes and red-shifts of galaxies as well as the distribution of clusters of galaxies over a large fraction of the sky. Although the main driver for Euclid is the nature of dark energy, Euclid science covers a vast range of topics, from cosmology to galaxy evolution to planetary research. In this review we focus on cosmology and fundamental physics, with a strong emphasis on science beyond the current standard models. We discuss five broad topics: dark energy and modified gravity, dark matter, initial conditions, basic assumptions and questions of methodology in the data analysis. This review has been planned and carried out within Euclid's Theory Working Group and is meant to provide a guide to the scientific themes that will underlie the activity of the group during the preparation of the Euclid mission.

Regression modeling of ground-water flow

USGS Publications Warehouse

Cooley, R.L.; Naff, R.L.

1985-01-01

Nonlinear multiple regression methods are developed to model and analyze groundwater flow systems. Complete descriptions of regression methodology as applied to groundwater flow models allow scientists and engineers engaged in flow modeling to apply the methods to a wide range of problems. Organization of the text proceeds from an introduction that discusses the general topic of groundwater flow modeling, to a review of basic statistics necessary to properly apply regression techniques, and then to the main topic: exposition and use of linear and nonlinear regression to model groundwater flow. Statistical procedures are given to analyze and use the regression models. A number of exercises and answers are included to exercise the student on nearly all the methods that are presented for modeling and statistical analysis. Three computer programs implement the more complex methods. These three are a general two-dimensional, steady-state regression model for flow in an anisotropic, heterogeneous porous medium, a program to calculate a measure of model nonlinearity with respect to the regression parameters, and a program to analyze model errors in computed dependent variables such as hydraulic head. (USGS)

Introduction to systematic reviews in animal agriculture and veterinary medicine.

PubMed

Sargeant, J M; O'Connor, A M

2014-06-01

This article is the first in a series of six articles related to systematic reviews in animal agriculture and veterinary medicine. In this article, we overview the methodology of systematic reviews and provide a discussion of their use. Systematic reviews differ qualitatively from traditional reviews by explicitly defining a specific review question, employing methods to reduce bias in the selection and inclusion of studies that address the review question (including a systematic and specified search strategy, and selection of studies based on explicit eligibility criteria), an assessment of the risk of bias for included studies and objectively summarizing the results qualitatively or quantitatively (i.e. via meta-analysis). Systematic reviews have been widely used to address human healthcare questions and are increasingly being used in veterinary medicine. Systematic reviews can provide veterinarians and other decision-makers with a scientifically defensible summary of the current state of knowledge on a topic without the need for the end-user to read the vast amount of primary research related to that topic. © 2014 Blackwell Verlag GmbH.

Expert systems and simulation models; Proceedings of the Seminar, Tucson, AZ, November 18, 19, 1985

NASA Technical Reports Server (NTRS)

1986-01-01

The seminar presents papers on modeling and simulation methodology, artificial intelligence and expert systems, environments for simulation/expert system development, and methodology for simulation/expert system development. Particular attention is given to simulation modeling concepts and their representation, modular hierarchical model specification, knowledge representation, and rule-based diagnostic expert system development. Other topics include the combination of symbolic and discrete event simulation, real time inferencing, and the management of large knowledge-based simulation projects.

Probabilistic fatigue methodology for six nines reliability

NASA Technical Reports Server (NTRS)

Everett, R. A., Jr.; Bartlett, F. D., Jr.; Elber, Wolf

1990-01-01

Fleet readiness and flight safety strongly depend on the degree of reliability that can be designed into rotorcraft flight critical components. The current U.S. Army fatigue life specification for new rotorcraft is the so-called six nines reliability, or a probability of failure of one in a million. The progress of a round robin which was established by the American Helicopter Society (AHS) Subcommittee for Fatigue and Damage Tolerance is reviewed to investigate reliability-based fatigue methodology. The participants in this cooperative effort are in the U.S. Army Aviation Systems Command (AVSCOM) and the rotorcraft industry. One phase of the joint activity examined fatigue reliability under uniquely defined conditions for which only one answer was correct. The other phases were set up to learn how the different industry methods in defining fatigue strength affected the mean fatigue life and reliability calculations. Hence, constant amplitude and spectrum fatigue test data were provided so that each participant could perform their standard fatigue life analysis. As a result of this round robin, the probabilistic logic which includes both fatigue strength and spectrum loading variability in developing a consistant reliability analysis was established. In this first study, the reliability analysis was limited to the linear cumulative damage approach. However, it is expected that superior fatigue life prediction methods will ultimately be developed through this open AHS forum. To that end, these preliminary results were useful in identifying some topics for additional study.

An update on technical and methodological aspects for cardiac PET applications.

PubMed

Presotto, Luca; Busnardo, Elena; Gianolli, Luigi; Bettinardi, Valentino

2016-12-01

Positron emission tomography (PET) is indicated for a large number of cardiac diseases: perfusion and viability studies are commonly used to evaluate coronary artery disease; PET can also be used to assess sarcoidosis and endocarditis, as well as to investigate amyloidosis. Furthermore, a hot topic for research is plaque characterization. Most of these studies are technically very challenging. High count rates and short acquisition times characterize perfusion scans while very small targets have to be imaged in inflammation/infection and plaques examinations. Furthermore, cardiac PET suffers from respiratory and cardiac motion blur. Each type of studies has specific requirements from the technical and methodological point of view, thus PET systems with overall high performances are required. Furthermore, in the era of hybrid PET/computed tomography (CT) and PET/Magnetic Resonance Imaging (MRI) systems, the combination of complementary functional and anatomical information can be used to improve diagnosis and prognosis. Moreover, PET images can be qualitatively and quantitatively improved exploiting information from the other modality, using advanced algorithms. In this review we will report the latest technological and methodological innovations for PET cardiac applications, with particular reference to the state of the art of the hybrid PET/CT and PET/MRI. We will also report the most recent advancements in software, from reconstruction algorithms to image processing and analysis programs.

Conceptual Strategies for Operationalizing Multicultural Curricula.

ERIC Educational Resources Information Center

Belay, Getinet

1992-01-01

Discusses the trends in multiculturalism research, the importance of cultural diversity in the curriculum, and strategies for operationalizing a multicultural curriculum in library and information science education. Topics addressed include pedagogical methodology, leaning style, and course and program design. (97 references) (EA)

Expanding Perspectives on HRD Research. Symposium.

ERIC Educational Resources Information Center

2002

This document contains three papers from a symposium on expanding perspectives in human resource development (HRD) research. "The Concept of Culture in International and Comparative HRD Research: Methodological Problems and Possible Solutions" (Alexander Ardichvili, K. Peter Kuchinke) discusses the following topics: (1) alternative…

Children's Eye Movements in Reading: A Commentary

ERIC Educational Resources Information Center

Rayner, Keith; Ardoin, Scott P.; Binder, Katherine S.

2013-01-01

are discussed. Specifically, the following topics are addressed: (1) basic methodological issues, (2) prior research findings on children's reading, (3) research that is missing in the literature regarding children's eye movements during reading, (4) applied…

Comparing Three Innovative Instructional Systems.

ERIC Educational Resources Information Center

Dunn, Rita; Waggoner, Barbara

1995-01-01

Examines the differences between three instructional systems: learning styles, neuro-linguistic programming, and "Suggestopoedia." Topics include the philosophical basis of each system; teaching methodologies; the use of multimedia; the use of time; environmental settings; and approaches to human emotion, individual sociological differences, and…

Computational Fluid Dynamics: Past, Present, And Future

NASA Technical Reports Server (NTRS)

Kutler, Paul

1988-01-01

Paper reviews development of computational fluid dynamics and explores future prospects of technology. Report covers such topics as computer technology, turbulence, development of solution methodology, developemnt of algorithms, definition of flow geometries, generation of computational grids, and pre- and post-data processing.

The Introductory College Business Course: A New Dimension

ERIC Educational Resources Information Center

Podell, Joel; And Others

1977-01-01

Describes various methodologies used at the Queensboro Community College, New York, to enrich some of the topics traditionally included in the introductory course such as union management relations, social responsibility and business ethics, internal organization structure, and small business management. (TA)

Low-cost commercial transport

NASA Technical Reports Server (NTRS)

Mcpherson, J.

1991-01-01

The topics presented are covered in viewgraph form. The objectives are to develop and validate technology, design tools and methodologies to enable the low cost commercial development and operational uses of hydrogen and hydrocarbon fueled liquid engines, low pressure booster engines and hybrid engines.

12th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals: susceptibility to environmental hazards.

PubMed Central

Barrett, J C; Vainio, H; Peakall, D; Goldstein, B D

1997-01-01

The 12th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC) considered the topic of methodologies for determining human and ecosystem susceptibility to environmental hazards. The report prepared at the meeting describes measurement of susceptibility through the use of biological markers of exposure, biological markers of effect, and biomarkers directly indicative of susceptibility of humans or of ecosystems. The utility and validity of these biological markers for the study of susceptibility are evaluated, as are opportunities for developing newer approaches for the study of humans or of ecosystems. For the first time a SGOMSEC workshop also formally considered the issue of ethics in relation to methodology, an issue of particular concern for studies of susceptibility. PMID:9255554

In search of educational efficiency: 30 years of Medical Education's top-cited articles.

PubMed

Rangel, J Cristian; Cartmill, Carrie; Martimianakis, Maria Athina; Kuper, Ayelet; Whitehead, Cynthia R

2017-09-01

Academic journals represent shared spaces wherein the significance of thematic areas, methodologies and paradigms are debated and shaped through collective engagement. By studying journals in their historical and cultural contexts, the academic community can gain insight into the ways in which authors and audiences propose, develop, harness, revise and discard research subjects, methodologies and practices. Thirty top-cited articles published in Medical Education between 1986 and 2014 were analysed in a two-step process. First, a descriptive classification of articles allowed us to quantify the frequency of content areas over the time span studied. Secondly, a discourse analysis was conducted to identify the continuities, disruptions and tensions within the three most prominent content areas. The top-cited articles in Medical Education focused on three major areas of interest: problem-based learning, simulation and assessment. In each of these areas of interest, we noted a tension between the desire to produce and apply standardised tools, and the recognition that the contexts of medical education are highly variable and influenced by political and financial considerations. The general preoccupation with achieving efficiency may paradoxically jeopardise the ability of medical schools to address the contextual needs of students, teachers and patients. Understanding the topics of interest for a journal's scholarly audience and how these topics are discursively positioned, provides important information for researchers in deciding how they wish to engage with the field, as well as for educators as they assess the relevance of educational products for their local contexts. © 2017 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

Challenges in systematic reviews: synthesis of topics related to the delivery, organization, and financing of health care.

PubMed

Bravata, Dena M; McDonald, Kathryn M; Shojania, Kaveh G; Sundaram, Vandana; Owens, Douglas K

2005-06-21

Some important health policy topics, such as those related to the delivery, organization, and financing of health care, present substantial challenges to established methods for evidence synthesis. For example, such reviews may ask: What is the effect of for-profit versus not-for-profit delivery of care on patient outcomes? Or, which strategies are the most effective for promoting preventive care? This paper describes innovative methods for synthesizing evidence related to the delivery, organization, and financing of health care. We found 13 systematic reviews on these topics that described novel methodologic approaches. Several of these syntheses used 3 approaches: conceptual frameworks to inform problem formulation, systematic searches that included nontraditional literature sources, and hybrid synthesis methods that included simulations to address key gaps in the literature. As the primary literature on these topics expands, so will opportunities to develop additional novel methods for performing high-quality comprehensive syntheses.

Co-Citation Analysis of Articles Published in Substance Abuse Journals: Intellectual Structure and Research Fields (2001-2012).

PubMed

González-Alcaide, Gregorio; Calafat, Amador; Becoña, Elisardo; Thijs, Bart; Glänzel, Wolfgang

2016-09-01

The purpose of this study is to introduce a new methodology in the field of substance abuse, namely, co-citation analysis, which uses the bibliographic references of publications to establish the main thematic areas being researched and to identify the seminal documents that have contributed to establishing the intellectual foundation of the discipline at the present time. We identified all bibliographic references that were cited in documents published in the substance abuse journals included in the Journal Citation Reports in the 2001-2012 period, generating a co-citation matrix. This matrix was used to perform a co-citation network analysis. The co-citation network analysis led to the identification of 56 prominent research clusters that bring together 698 documents; their subject matter constitutes the foundation of the discipline in the field's journals. Substance abuse research is dominated by a few core topics; chief among them are tools for measuring and diagnosing dependence, as well as therapeutic approaches to treat alcohol abuse and nicotine addiction. Other areas of note include epidemiological studies, research on drug user motivation (particularly among young people), binge drinking, social support mediators and networks, opioid dependence, consumption and effects of cannabis, basic research on brain damage, genetic factors associated with substance use, and the physiological and neurological determinants of abstinence syndrome. The main works of reference that we identified were published in a small number of journals, which establish the intellectual, conceptual, and methodological basis of the discipline.

[Visualizing Research Lines in Public Health: An analysis Based on Bibliometric Maps Applied to the Revista Española de Salud Pública (2006-2015)].

PubMed

Gálvez, Carmen

2016-12-01

Identifying research lines is essential to understand the knowledge structure of a scientific domain. The aim of this study was to identify the main research topics of within the domain of public health, in the Revista Española de Saslud Pública during 2006-2015. Original articles included in the Social Sciences Citation Index (SSCI) database, available online through the Web of Science (WoS), were selected. The analysis units used were the keywords, KeyWords Plus (KW+), extracted automatically by SSCI. With KW+ obtained bibliometric, maps were created using a methodology based on the combination of co-word analysis, co-word analysis, clustering techniques and visualization techniques. We analyzed 512 documents, of which 176 KW+ were obtained with a frequency greater than or equal to 3. The results were bidimensional bibliometric maps with thematic groupings of KW+, representing the main research fronts: i) epidemiology, risk control programs disease and, in general, service organization and health policies; ii) infectious diseases, principally HIV; iii) a progressive increase in several lines interrelated with cardiovascular diseases (CVD); iv) a line multidimensional dedicated to different aspects associated to the quality of life related to health (HRQoL); and v) an emerging line linked to binge drinking. For the multidisciplinary and multidimensional nature of public health, the construction of bibliometric maps is an appropriate methodology to understand the knowledge structure of this scientific domain.

In Vivo Methods for the Assessment of Topical Drug Bioavailability

PubMed Central

Herkenne, Christophe; Alberti, Ingo; Naik, Aarti; Kalia, Yogeshvar N.; Mathy, François-Xavier; Préat, Véronique

2007-01-01

This paper reviews some current methods for the in vivo assessment of local cutaneous bioavailability in humans after topical drug application. After an introduction discussing the importance of local drug bioavailability assessment and the limitations of model-based predictions, the focus turns to the relevance of experimental studies. The available techniques are then reviewed in detail, with particular emphasis on the tape stripping and microdialysis methodologies. Other less developed techniques, including the skin biopsy, suction blister, follicle removal and confocal Raman spectroscopy techniques are also described. PMID:17985216

Synthesis of discipline-based education research in physics

NASA Astrophysics Data System (ADS)

Docktor, Jennifer L.; Mestre, José P.

2014-12-01

This paper presents a comprehensive synthesis of physics education research at the undergraduate level. It is based on work originally commissioned by the National Academies. Six topical areas are covered: (1) conceptual understanding, (2) problem solving, (3) curriculum and instruction, (4) assessment, (5) cognitive psychology, and (6) attitudes and beliefs about teaching and learning. Each topical section includes sample research questions, theoretical frameworks, common research methodologies, a summary of key findings, strengths and limitations of the research, and areas for future study. Supplemental material proposes promising future directions in physics education research.

Orbital stability analysis in biomechanics: a systematic review of a nonlinear technique to detect instability of motor tasks.

PubMed

Riva, F; Bisi, M C; Stagni, R

2013-01-01

Falls represent a heavy economic and clinical burden on society. The identification of individual chronic characteristics associated with falling is of fundamental importance for the clinicians; in particular, the stability of daily motor tasks is one of the main factors that the clinicians look for during assessment procedures. Various methods for the assessment of stability in human movement are present in literature, and methods coming from stability analysis of nonlinear dynamic systems applied to biomechanics recently showed promise. One of these techniques is orbital stability analysis via Floquet multipliers. This method allows to measure orbital stability of periodic nonlinear dynamic systems and it seems a promising approach for the definition of a reliable motor stability index, taking into account for the whole task cycle dynamics. Despite the premises, its use in the assessment of fall risk has been deemed controversial. The aim of this systematic review was therefore to provide a critical evaluation of the literature on the topic of applications of orbital stability analysis in biomechanics, with particular focus to methodologic aspects. Four electronic databases have been searched for articles relative to the topic; 23 articles were selected for review. Quality of the studies present in literature has been assessed with a customised quality assessment tool. Overall quality of the literature in the field was found to be high. The most critical aspect was found to be the lack of uniformity in the implementation of the analysis to biomechanical time series, particularly in the choice of state space and number of cycles to include in the analysis. Copyright © 2012 Elsevier B.V. All rights reserved.

Chemical Synthesis of Complex Molecules Using Nanoparticle Catalysis

PubMed Central

Cong, Huan; Porco, John A.

2011-01-01

Nanoparticle catalysis has emerged as an active topic in organic synthesis. Of particular interest is the development of enabling methodologies to efficiently assemble complex molecules using nanoparticle catalysis. This Viewpoint highlights recent developments and discusses future perspectives in this emerging field. PMID:22347681

Coastal Studies in a Comprehensive Summer Field Geology Course.

ERIC Educational Resources Information Center

Cameron, Barry; Jones, Richard J.

1979-01-01

Describes a college geology course that incorporates a coastal segment. Field studies are done on Plum Island and include examining beaches, dune fields, and an adjacent marsh and spit. Topics include sedimentation, coastal geomorphology, botanical effects, and coastal studies methodology. (MA)

Hong Kong Papers in Linguistics and Language Teaching.

ERIC Educational Resources Information Center

Hong Kong Papers in Linguistics and Language Teaching, 1995

1995-01-01

This serial presents articles, reports, and conference reports on various topics concerned with language-related areas, including general linguistics, teaching methodology, curriculum development, testing, evaluation, educational technology, language planning, and bilingual education. Articles in this volume are: (1) "Task Difficulty From the…

An Experimental Fish Ethology Unit.

ERIC Educational Resources Information Center

Fisher, Ronald L., Jr.; Novak, John A.

1984-01-01

Describes a series of four experiments designed for small group involvement (each requiring 6 days) emphasizing students' scientific methodology. Topics include: feeding behavior; light/temperature effects on reproduction; effect of density on feeding; and altered male/female ratios on male behavior. Each experiment includes introduction, material…

Evaluation: Review of the Past, Preview of the Future.

ERIC Educational Resources Information Center

Smith, M. F.

1994-01-01

This paper summarized contributors' ideas about evaluation as a field and where it is going. Topics discussed were qualitative versus quantitative debate; evaluation's purpose; professionalization; program failure; program development; evaluators as advocates; evaluation knowledge; evaluation expansion; and methodology and design. (SLD)

75 FR 4831 - Center for Scientific Review; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-29

... Emphasis Panel Molecular Biology. Date: March 2, 2010. Time: 12 p.m. to 2 p.m. Agenda: To review and...; Special Topic: Diet and Physical Activity Methodologies. Date: March 3-4, 2010. Time: 8 a.m. to 5 p.m...

Designing and Creating Computer-Assisted Instruction.

ERIC Educational Resources Information Center

McMeen, George R.

Designed to encourage the use of a defined methodology and careful planning in creating computer-assisted instructional programs, this paper describes the instructional design process, compares computer-assisted instruction (CAI) and programmed instruction (PI), and discusses pragmatic concerns in computer programming. Topics addressed include:…

Seventh NASTRAN User's Colloquium

NASA Technical Reports Server (NTRS)

1978-01-01

The general application of finite element methodology and the specific application of NASTRAN to a wide variety of static and dynamic structural problems are described. Topics include: fluids and thermal applications, NASTRAN programming, substructuring methods, unique new applications, general auxiliary programs, specific applications, and new capabilities.

The Evolution of Family Studies Research.

ERIC Educational Resources Information Center

Emery, Beth C.; Lloyd, Sally A.

2001-01-01

This review of methodological, theoretical, and topical trends in family studies research covers changes in definitions of family and in marriage, parent-child relationships, and family social ecology. Issues discussed include marital satisfaction, violence, social construction of gender, family-work relationship, parenting roles, socialization,…

A Feminist Paradigm for Library and Information Science.

ERIC Educational Resources Information Center

Hannigan, Jane Anne; Crew, Hilary

1993-01-01

Discussion of feminist scholarship and feminist thinking focuses on feminism in librarianship. Topics addressed include research methodologies; implications for library and information science; a feminist model, including constructed knowledge; standpoint theory; benefits of feminist scholarship; and a library model. (Contains 14 references.) (LRW)

A systematic review of nursing research priorities on health system and services in the Americas.

PubMed

Garcia, Alessandra Bassalobre; Cassiani, Silvia Helena De Bortoli; Reveiz, Ludovic

2015-03-01

To systematically review literature on priorities in nursing research on health systems and services in the Region of the Americas as a step toward developing a nursing research agenda that will advance the Regional Strategy for Universal Access to Health and Universal Health Coverage. This was a systematic review of the literature available from the following databases: Web of Science, PubMed, LILACS, and Google. Documents considered were published in 2008-2014; in English, Spanish, or Portuguese; and addressed the topic in the Region of the Americas. The documents selected had their priority-setting process evaluated according to the "nine common themes for good practice in health research priorities." A content analysis collected all study questions and topics, and sorted them by category and subcategory. Of 185 full-text articles/documents that were assessed for eligibility, 23 were selected: 12 were from peer-reviewed journals; 6 from nursing publications; 4 from Ministries of Health; and 1 from an international organization. Journal publications had stronger methodological rigor; the majority did not present a clear implementation or evaluation plan. After compiling the 444 documents' study questions and topics, the content analysis resulted in a document with 5 categories and 16 subcategories regarding nursing research priorities on health systems and services. Research priority-setting is a highly important process for health services improvement and resources optimization, but implementation and evaluation plans are rarely included. The resulting document will serve as basis for the development of a new nursing research agenda focused on health systems and services, and shaped to advance universal health coverage and universal access to health.

RECOVER evidence and knowledge gap analysis on veterinary CPR. Part 1: Evidence analysis and consensus process: collaborative path toward small animal CPR guidelines.

PubMed

Boller, Manuel; Fletcher, Daniel J

2012-06-01

To describe the methodology used by the Reassessment Campaign on Veterinary Resuscitation (RECOVER) to evaluate the scientific evidence relevant to small animal CPR and to compose consensus-based clinical CPR guidelines for dogs and cats. This report is part of a series of 7 articles on the RECOVER evidence and knowledge gap analysis and consensus-based small animal CPR guidelines. It describes the organizational structure of RECOVER, the evaluation process employed, consisting of standardized literature searches, the analysis of relevant articles according to study design, species and predefined quality markers, and the drafting of clinical CPR guidelines based on these data. Therefore, this article serves as the methodology section for the subsequent 6 RECOVER articles. Academia, referral practice. RECOVER is a collaborative initiative that systematically evaluated the evidence on 74 topics relevant to small animal CPR and generated 101 clinical CPR guidelines from this analysis. All primary contributors were veterinary specialists, approximately evenly split between academic institutions and private referral practices. The evidence evaluation and guideline drafting processes were conducted according to a predefined sequence of steps designed to reduce bias and increase the repeatability of the findings, including multiple levels of review, culminating in a consensus process. Many knowledge gaps were identified that will allow prioritization of research efforts in veterinary CPR. Collaborative systematic evidence review is organizationally challenging but feasible and effective in veterinary medicine. More experience is needed to refine the process. © Veterinary Emergency and Critical Care Society 2012.

The 300 most cited articles published in periodontology.

PubMed

Faggion, Clovis Mariano; Málaga, Lilian; Monje, Alberto; Trescher, Anna-Lena; Listl, Stefan; Alarcón, Marco Antonio

2017-07-01

It is important to evaluate the characteristics of the most cited articles in any specialty. The number of citations may be a proxy for clinical and research activity. The objectives of the present methodological study were (1) to report the characteristics of the 300 most cited articles in periodontology and (2) to explore the association of these characteristics with the number of citations. We searched in the Web of Science database for the 300 most cited articles published in periodontology on June 15, 2015. We described characteristics of the articles such as type of study, type of scientific journal, topic reported, year of publication, affiliation of the first author of the article, and impact factor. Linear regression analysis was used to investigate associations of these variables with the number of citations. The search retrieved approximately 155,356 publications; out of the studies that met the eligibility criteria, the 300 most cited were included for analysis. Comprising more than 50 % of the included articles, basic biology and the detection of bacteria were the most prevalent topics. Narrative reviews were the most frequent type of article (27 % of the sample). Regression analysis demonstrated that some characteristics, for example "narrative reviews," are more prone to be cited than others. We conclude that scientific evolution in periodontology has been based more on narrative reviews than on reproducible systematic reviews. Future research is encouraged to elucidate the extent to which scientific progress is improved through systematic compared with narrative reviews.

Making the First Cut: An Analysis of Academic Medicine Editors' Reasons for Not Sending Manuscripts Out for External Peer Review.

PubMed

Meyer, Holly S; Durning, Steven J; Sklar, David P; Maggio, Lauren A

2018-03-01

Manuscripts submitted to Academic Medicine (AM) undergo an internal editor review to determine whether they will be sent for external peer review. Increasingly, manuscripts are rejected at this early stage. This study seeks to inform scholars about common reasons for internal editor review rejections, increase transparency of the process, and provide suggestions for improving submissions. A mixed-methods approach was used to retrospectively analyze editors' free-text comments. Descriptive content analysis was performed of editors' comments for 369 manuscripts submitted between December 2014 and December 2015, and rejected prior to external peer review from AM. Comments were analyzed, categorized, and counted for explicit reasons for rejection. Nine categories of rejection reasons were identified: ineffective study question and/or design (338; 92%); suboptimal data collection process (180; 49%); weak discussion and/or conclusions (139; 37%); unimportant or irrelevant topic to the journal's mission (137; 37%); weak data analysis and/or presentation of results (120; 33%); text difficult to follow, to understand (89; 24%); inadequate or incomplete introduction (67; 18%); other publishing considerations (42; 11%); and issues with scientific conduct (20; 5%). Manuscripts had, on average, three or more reasons for rejection. Findings suggest that clear identification of a research question that is addressed by a well-designed study methodology on a topic aligned with the mission of the journal would address many of the problems that lead to rejection through the internal review process. The findings also align with research on external peer review.

A Human Factors Evaluation of a Methodology for Pressurized Crew Module Acceptability for Zero-Gravity Ingress of Spacecraft

NASA Technical Reports Server (NTRS)

Sanchez, Merri J.

2000-01-01

This project aimed to develop a methodology for evaluating performance and acceptability characteristics of the pressurized crew module volume suitability for zero-gravity (g) ingress of a spacecraft and to evaluate the operational acceptability of the NASA crew return vehicle (CRV) for zero-g ingress of astronaut crew, volume for crew tasks, and general crew module and seat layout. No standard or methodology has been established for evaluating volume acceptability in human spaceflight vehicles. Volume affects astronauts'ability to ingress and egress the vehicle, and to maneuver in and perform critical operational tasks inside the vehicle. Much research has been conducted on aircraft ingress, egress, and rescue in order to establish military and civil aircraft standards. However, due to the extremely limited number of human-rated spacecraft, this topic has been un-addressed. The NASA CRV was used for this study. The prototype vehicle can return a 7-member crew from the International Space Station in an emergency. The vehicle's internal arrangement must be designed to facilitate rapid zero-g ingress, zero-g maneuverability, ease of one-g egress and rescue, and ease of operational tasks in multiple acceleration environments. A full-scale crew module mockup was built and outfitted with representative adjustable seats, crew equipment, and a volumetrically equivalent hatch. Human factors testing was conducted in three acceleration environments using ground-based facilities and the KC-135 aircraft. Performance and acceptability measurements were collected. Data analysis was conducted using analysis of variance and nonparametric techniques.

Trends in health sciences library and information science research: an analysis of research publications in the Bulletin of the Medical Library Association and Journal of the Medical Library Association from 1991 to 2007*

PubMed Central

Gore, Sally A.; Nordberg, Judith M.; Palmer, Lisa A.

2009-01-01

Objective: This study analyzed trends in research activity as represented in the published research in the leading peer-reviewed professional journal for health sciences librarianship. Methodology: Research articles were identified from the Bulletin of the Medical Library Association and Journal of the Medical Library Association (1991–2007). Using content analysis and bibliometric techniques, data were collected for each article on the (1) subject, (2) research method, (3) analytical technique used, (4) number of authors, (5) number of citations, (6) first author affiliation, and (7) funding source. The results were compared to a previous study, covering the period 1966 to 1990, to identify changes over time. Results: Of the 930 articles examined, 474 (51%) were identified as research articles. Survey (n = 174, 37.1%) was the most common methodology employed, quantitative descriptive statistics (n = 298, 63.5%) the most used analytical technique, and applied topics (n = 332, 70%) the most common type of subject studied. The majority of first authors were associated with an academic health sciences library (n = 264, 55.7%). Only 27.4% (n = 130) of studies identified a funding source. Conclusion: This study's findings demonstrate that progress is being made in health sciences librarianship research. There is, however, room for improvement in terms of research methodologies used, proportion of applied versus theoretical research, and elimination of barriers to conducting research for practicing librarians. PMID:19626146

A method for studying decision-making by guideline development groups.

PubMed

Gardner, Benjamin; Davidson, Rosemary; McAteer, John; Michie, Susan

2009-08-05

Multidisciplinary guideline development groups (GDGs) have considerable influence on UK healthcare policy and practice, but previous research suggests that research evidence is a variable influence on GDG recommendations. The Evidence into Recommendations (EiR) study has been set up to document social-psychological influences on GDG decision-making. In this paper we aim to evaluate the relevance of existing qualitative methodologies to the EiR study, and to develop a method best-suited to capturing influences on GDG decision-making. A research team comprised of three postdoctoral research fellows and a multidisciplinary steering group assessed the utility of extant qualitative methodologies for coding verbatim GDG meeting transcripts and semi-structured interviews with GDG members. A unique configuration of techniques was developed to permit data reduction and analysis. Our method incorporates techniques from thematic analysis, grounded theory analysis, content analysis, and framework analysis. Thematic analysis of individual interviews conducted with group members at the start and end of the GDG process defines discrete problem areas to guide data extraction from GDG meeting transcripts. Data excerpts are coded both inductively and deductively, using concepts taken from theories of decision-making, social influence and group processes. These codes inform a framework analysis to describe and explain incidents within GDG meetings. We illustrate the application of the method by discussing some preliminary findings of a study of a National Institute for Health and Clinical Excellence (NICE) acute physical health GDG. This method is currently being applied to study the meetings of three of NICE GDGs. These cover topics in acute physical health, mental health and public health, and comprise a total of 45 full-day meetings. The method offers potential for application to other health care and decision-making groups.

Prioritizing comparative effectiveness research for cancer diagnostics using a regional stakeholder approach.

PubMed

Klein, Gregory; Gold, Laura S; Sullivan, Sean D; Buist, Diana S M; Ramsey, Scott; Kreizenbeck, Karma; Snell, Kyle; Loggers, Elizabeth Trice; Gifford, Joseph; Watkins, John B; Kessler, Larry

2012-05-01

This paper describes our process to engage regional stakeholders for prioritizing comparative effectiveness research (CER) in cancer diagnostics. We also describe a novel methodology for incorporating stakeholder data and input to inform the objectives of selected CER studies. As an integrated component to establishing the infrastructure for community-based CER on diagnostic technologies, we have assembled a regional stakeholder group composed of local payers, clinicians and state healthcare representatives to not only identify and prioritize CER topics most important to the western Washington State region, but also to inform the study design of selected research areas. A landscape analysis process combining literature searches, expert consultations and stakeholder discussions was used to identify possible CER topics in cancer diagnostics. Stakeholders prioritized the top topics using a modified Delphi/group-nominal method and a standardized evaluation criteria framework to determine a final selected CER study area. Implementation of the selected study was immediate due to a unique American Recovery and Reinvestment Act funding structure involving the same researchers and stakeholders in both the prioritization and execution phases of the project. Stakeholder engagement was enhanced after study selection via a rapid analysis of a subset of payers' internal claims, coordinated by the research team, to obtain summary data of imaging patterns of use. Results of this preliminary analysis, which we termed an 'internal analysis,' were used to determine with the stakeholders the most important and feasible study objectives. Stakeholders identified PET and MRI in cancers including breast, lung, lymphoma and colorectal as top priorities. In an internal analysis of breast cancer imaging, summary data from three payers demonstrated utilization rates of advanced imaging increased between 2002 and 2009 in the study population, with a great deal of variability in use between different health plans. Assessing whether breast MRI affects treatment decisions was the top breast cancer study objective selected by the stakeholders. There were other high-priority research areas including whether MRI use improved survival that were not deemed feasible with the length of follow-up time following MRI adoption. Continuous stakeholder engagement greatly enhanced their enthusiasm for the project. We believe CER implementation will be more successful when undertaken by regional stakeholders.

Comprehensive Design Reliability Activities for Aerospace Propulsion Systems

NASA Technical Reports Server (NTRS)

Christenson, R. L.; Whitley, M. R.; Knight, K. C.

2000-01-01

This technical publication describes the methodology, model, software tool, input data, and analysis result that support aerospace design reliability studies. The focus of these activities is on propulsion systems mechanical design reliability. The goal of these activities is to support design from a reliability perspective. Paralleling performance analyses in schedule and method, this requires the proper use of metrics in a validated reliability model useful for design, sensitivity, and trade studies. Design reliability analysis in this view is one of several critical design functions. A design reliability method is detailed and two example analyses are provided-one qualitative and the other quantitative. The use of aerospace and commercial data sources for quantification is discussed and sources listed. A tool that was developed to support both types of analyses is presented. Finally, special topics discussed include the development of design criteria, issues of reliability quantification, quality control, and reliability verification.

Qualitative Research in the CJA/RCV: An 18-Year Analysis (1995-2012).

PubMed

Humble, Áine M; Green, Maureen

2016-03-01

Some researchers have suggested that qualitative research is increasing in the gerontology field, but little systematic analysis has tested this assertion. Using the Canadian Journal on Aging/La Revue canadienne du vieillissement as a case study, we analysed articles reporting on original research from 1995 to 2012. One in four articles were qualitative, and results in three-year intervals show a clear increase in qualitative research findings during this 18-year time frame: (a) 1995-1997: 10 per cent; (b) 1998-2000: 19 per cent; (c) 2001-2003: 25 per cent; (d) 2004-2006: 25 per cent; (e) 2007-2009: 29 per cent; and (f) 2010-2012: 43 per cent. In all time intervals (with the exception of 2004-2006), French language articles were more likely to use a qualitative research design compared to English language articles. Topics, methodologies, and data collection strategies are also discussed.

Child and youth practice area publications in the American Journal of Occupational Therapy in 2008 and 2009: a content analysis, methodology overview, and summary.

PubMed

Brown, Ted

2010-01-01

In this review, 39 articles published in the American journal of occupational therapy in 2008 and 2009 that were categorized in the practice area of children and youth were examined using content analysis. The most frequent type of research published was basic research, which accounted for 38.5% (n=15) of the 39 studies published on the topic. Instrument development and testing and effectiveness studies were the next two most frequently noted research approaches, accounting for 25.6% (n=10) and 20.5% (n=8) of the studies, respectively. Among the 8 effectiveness studies, the level of evidence distribution was as follows: Level I, 3; Level III, 2; Level IV, 1; and Level V, 2. Quantitative studies were the predominant research paradigm used with 76.9% (n=30) of the studies.

Teaching Geography and History through GIS: Application on Greek cultural sites

NASA Astrophysics Data System (ADS)

Skentos, Athanasios; Pavlopoulos, Kosmas; Galani, Apostolia; Theodorakopoulou, Katerina; Kritikos, Giorgos

2013-04-01

This study deals with the presentation of cultural succession in Greek space-time through a GIS application, associated with core concepts of geographic and historical education. Through the specific application students will be able to develop five distinct skills: sense of time-scale, historical and geographic comprehension, spatial analysis and interpretation, ability to perform geo-historical research, and procedure of geo-historical decision-making. The methodology is based on the calibration of a set of criteria for each cultural site that covers the topics of economy, geomorphology, society, religion, art and science. Further analysis of these data forms a geodatabase. In addition, palaeogeographic and historical maps of the cultural sites derived by the geodatabase provide information about temporal and spatial changes. As result, students will be able to develop a multidimensional and interdisciplinary approach, in order to reconstruct the evolution of the site.

PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways): Introduction and overview

NASA Astrophysics Data System (ADS)

Ó Cofaigh, Colm; Briner, Jason P.; Kirchner, Nina; Lucchi, Renata G.; Meyer, Hanno; Kaufman, Darrell S.

2016-09-01

This special issue relates to the Second International Conference of the PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways) network which was held in Trieste, Italy in 2014. Twenty five papers are included and they address topics under four main themes: (1) The growth and decay of Arctic ice sheets; (2) Arctic sea ice and palaeoceanography; (3) Terrestrial Arctic environments and permafrost change; and (4) Holocene Arctic environmental change. Geographically the focus is circum-Arctic; the special issue includes detailed regional studies from Greenland, Scandinavia, Russia, and Arctic North America and the adjoining seas, as well as a series of synthesis-type, review papers on Fennoscandian Ice Sheet deglaciation and Holocene Arctic palaeo-climate change. The methodologies employed are diverse and include marine sediment core and geophysical investigations, terrestrial glacial geology and geomorphology, isotopic analysis of ground ice, palaeo-ecological analysis of lacustrine and terrestrial sedimentary archives, geochronology and numerical ice sheet modeling.

Investigating moral intensity with the World-Wide Web: a look at participant reactions and a comparison of methods.

PubMed

Frey, B F

2000-08-01

This paper reports the results of a vignette- and questionnaire-based research project over the World-Wide Web investigating the influence of moral intensity (MI) on decision making in a business context. A qualitative analysis of the feedback in terms of e-mail communications was used to provide insights into the reactions and responses of participants to both the research method and the topic of research. Implications are discussed, and some methodological recommendations are derived. Second, analysis of the quantitative results of the Web-based questionnaire administration indicated that three of the six MI components were particularly important determinants of several outcome variables. This pattern of results essentially replicated findings yielded by a previous mail administration of the survey, even though a smaller amount of variation in the outcome variables was accounted for. Neither occupational background nor the region of origin of participants measurably influenced the results.

A workshop on developing risk assessment methods for medical use of radioactive material. Volume 2: Supporting documents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tortorelli, J.P.

A workshop was held at the Idaho National Engineering Laboratory, August 16--18, 1994 on the topic of risk assessment on medical devices that use radioactive isotopes. Its purpose was to review past efforts to develop a risk assessment methodology to evaluate these devices, and to develop a program plan and a scoping document for future methodology development. This report contains presentation material and a transcript of the workshop. Participants included experts in the fields of radiation oncology, medical physics, risk assessment, human-error analysis, and human factors. Staff from the US Nuclear Regulatory Commission (NRC) associated with the regulation of medicalmore » uses of radioactive materials and with research into risk-assessment methods participated in the workshop. The workshop participants concurred in NRC`s intended use of risk assessment as an important technology in the development of regulations for the medical use of radioactive material and encouraged the NRC to proceed rapidly with a pilot study. Specific recommendations are included in the executive summary and the body of this report.« less

Poor methodological detail precludes experimental repeatability and hampers synthesis in ecology.

PubMed

Haddaway, Neal R; Verhoeven, Jos T A

2015-10-01

Despite the scientific method's central tenets of reproducibility (the ability to obtain similar results when repeated) and repeatability (the ability to replicate an experiment based on methods described), published ecological research continues to fail to provide sufficient methodological detail to allow either repeatability of verification. Recent systematic reviews highlight the problem, with one example demonstrating that an average of 13% of studies per year (±8.0 [SD]) failed to report sample sizes. The problem affects the ability to verify the accuracy of any analysis, to repeat methods used, and to assimilate the study findings into powerful and useful meta-analyses. The problem is common in a variety of ecological topics examined to date, and despite previous calls for improved reporting and metadata archiving, which could indirectly alleviate the problem, there is no indication of an improvement in reporting standards over time. Here, we call on authors, editors, and peer reviewers to consider repeatability as a top priority when evaluating research manuscripts, bearing in mind that legacy and integration into the evidence base can drastically improve the impact of individual research reports.

Clinical audit, a valuable tool to improve quality of care: General methodology and applications in nephrology

PubMed Central

Esposito, Pasquale; Dal Canton, Antonio

2014-01-01

Evaluation and improvement of quality of care provided to the patients are of crucial importance in the daily clinical practice and in the health policy planning and financing. Different tools have been developed, including incident analysis, health technology assessment and clinical audit. The clinical audit consist of measuring a clinical outcome or a process, against well-defined standards set on the principles of evidence-based medicine in order to identify the changes needed to improve the quality of care. In particular, patients suffering from chronic renal diseases, present many problems that have been set as topics for clinical audit projects, such as hypertension, anaemia and mineral metabolism management. Although the results of these studies have been encouraging, demonstrating the effectiveness of audit, overall the present evidence is not clearly in favour of clinical audit. These findings call attention to the need to further studies to validate this methodology in different operating scenarios. This review examines the principle of clinical audit, focusing on experiences performed in nephrology settings. PMID:25374819

Authors' response: the primacy of conscious decision making.

PubMed

Shanks, David R; Newell, Ben R

2014-02-01

The target article sought to question the common belief that our decisions are often biased by unconscious influences. While many commentators offer additional support for this perspective, others question our theoretical assumptions, empirical evaluations, and methodological criteria. We rebut in particular the starting assumption that all decision making is unconscious, and that the onus should be on researchers to prove conscious influences. Further evidence is evaluated in relation to the core topics we reviewed (multiple-cue judgment, deliberation without attention, and decisions under uncertainty), as well as priming effects. We reiterate a key conclusion from the target article, namely, that it now seems to be generally accepted that awareness should be operationally defined as reportable knowledge, and that such knowledge can only be evaluated by careful and thorough probing. We call for future research to pay heed to the different ways in which awareness can intervene in decision making (as identified in our lens model analysis) and to employ suitable methodology in the assessment of awareness, including the requirements that awareness assessment must be reliable, relevant, immediate, and sensitive.

Research in Counseling Psychology: Prospects and Recommendations.

ERIC Educational Resources Information Center

Gelso, Charles J.; And Others

1988-01-01

Presents summary of discussions on research from the Third National Conference for Counseling Psychology. Topics summarized include definition and image; methodological diversity in counseling research; multi- and cross-cultural issues; the connection of research to practice; and research training. Provides 15 recommendations for research in…

2012 national survey of bicyclist and pedestrian attitudes and behavior : volume 3 : methodology report

DOT National Transportation Integrated Search

2013-10-01

The 2012 National Survey of Bicyclist and Pedestrian Attitudes and Behavior is the second survey on this topic conducted for the National Highway Traffic Safety Administration (NHTSA). Data collection was conducted by Abt SRBI, Inc, a national resear...

Proceedings--symposium on recreation choice behavior

Treesearch

George H. Stankey; Stephen F. McCool

1985-01-01

Presents an overview paper and 11 contributed papers focused on the issue of the processes that underlie decision making by recreationists. The papers span a range of topics including the theory of choice behavior, empirical investigations of choice, and methodological approaches to the study of choice behavior.

Field Placement Treatments: A Comparative Study

ERIC Educational Resources Information Center

Parkison, Paul T.

2008-01-01

Field placement within teacher education represents a topic of interest for all preservice teacher programs. Present research addresses a set of important questions regarding field placement: (1) What pedagogical methodologies facilitate deep learning during field experiences? (2) Is there a significant difference in treatment effect for…

Some Remarks on the Theory of Political Education. German Studies Notes.

ERIC Educational Resources Information Center

Holtmann, Antonius

This theoretical discussion explores pedagogical assumptions of political education in West Germany. Three major methodological orientations are discussed: the normative-ontological, empirical-analytical, and dialectical-historical. The author recounts the aims, methods, and basic presuppositions of each of these approaches. Topics discussed…

Examiner Practices and Culturally Inflected Doctoral Theses

ERIC Educational Resources Information Center

Wisker, Gina; Robinson, Gillian

2014-01-01

Increase in numbers of postgraduate students worldwide represent an opportunity and necessity for nurturing and recognising the diversity of culturally inflected research topics, methodologies and expression. However, there are tensions in the definitions, encouragement and recognition of diversity in theses, and in balances of power in…

Implementation of a Refined Shear Rating Methodology for Prestressed Concrete Girder Bridges

DOT National Transportation Integrated Search

2017-12-01

Lower than desirable shear ratings at the ends of prestressed concrete beams have been the topic of ongoing research between MnDOT and the University of Minnesota. A recent study by the University of Minnesota entitled Investigation of Shear Distribu...

Conceptual and methodological issues in research on mindfulness and meditation.

PubMed

Davidson, Richard J; Kaszniak, Alfred W

2015-10-01

Both basic science and clinical research on mindfulness, meditation, and related constructs have dramatically increased in recent years. However, interpretation of these research results has been challenging. The present article addresses unique conceptual and methodological problems posed by research in this area. Included among the key topics is the role of first-person experience and how it can be best studied, the challenges posed by intervention research designs in which true double-blinding is not possible, the nature of control and comparison conditions for research that includes mindfulness or other meditation-based interventions, issues in the adequate description of mindfulness and related trainings and interventions, the question of how mindfulness can be measured, questions regarding what can and cannot be inferred from self-report measures, and considerations regarding the structure of study design and data analyses. Most of these topics are germane to both basic and clinical research studies and have important bearing on the future scientific understanding of mindfulness and meditation. (c) 2015 APA, all rights reserved).

Conceptual and Methodological Issues in Research on Mindfulness and Meditation

PubMed Central

Davidson, Richard J.; Kaszniak, Alfred W.

2015-01-01

Both basic science and clinical research on mindfulness, meditation, and related constructs has dramatically increased in recent years. However, interpretation of these research results has been challenging. The present article addresses unique conceptual and methodological problems posed by research in this area. Included among the key topics is the role of first person experience and how it can be best studied; the challenges posed by intervention research designs in which true double-blinding is not possible; the nature of control and comparison conditions for research that includes mindfulness or other meditation-based interventions; issues in the adequate description of mindfulness and related trainings and interventions; the question of how mindfulness can be measured; questions regarding what can and cannot be inferred from self-report measures; and considerations regarding the structure of study design and data analyses. Most of these topics are germane to both basic and clinical research studies and have important bearing on the future scientific understanding of mindfulness and meditation. PMID:26436310

A scoping review of scoping reviews: advancing the approach and enhancing the consistency

PubMed Central

Pham, Mai T; Rajić, Andrijana; Greig, Judy D; Sargeant, Jan M; Papadopoulos, Andrew; McEwen, Scott A

2014-01-01

Background The scoping review has become an increasingly popular approach for synthesizing research evidence. It is a relatively new approach for which a universal study definition or definitive procedure has not been established. The purpose of this scoping review was to provide an overview of scoping reviews in the literature. Methods A scoping review was conducted using the Arksey and O'Malley framework. A search was conducted in four bibliographic databases and the gray literature to identify scoping review studies. Review selection and characterization were performed by two independent reviewers using pretested forms. Results The search identified 344 scoping reviews published from 1999 to October 2012. The reviews varied in terms of purpose, methodology, and detail of reporting. Nearly three-quarter of reviews (74.1%) addressed a health topic. Study completion times varied from 2 weeks to 20 months, and 51% utilized a published methodological framework. Quality assessment of included studies was infrequently performed (22.38%). Conclusions Scoping reviews are a relatively new but increasingly common approach for mapping broad topics. Because of variability in their conduct, there is a need for their methodological standardization to ensure the utility and strength of evidence. © 2014 The Authors. Research Synthesis Methods published by John Wiley & Sons, Ltd. PMID:26052958

Around and about an application of the GAMLSS package to non-stationary flood frequency analysis

NASA Astrophysics Data System (ADS)

Debele, S. E.; Bogdanowicz, E.; Strupczewski, W. G.

2017-08-01

The non-stationarity of hydrologic processes due to climate change or human activities is challenging for the researchers and practitioners. However, the practical requirements for taking into account non-stationarity as a support in decision-making procedures exceed the up-to-date development of the theory and the of software. Currently, the most popular and freely available software package that allows for non-stationary statistical analysis is the GAMLSS (generalized additive models for location, scale and shape) package. GAMLSS has been used in a variety of fields. There are also several papers recommending GAMLSS in hydrological problems; however, there are still important issues which have not previously been discussed concerning mainly GAMLSS applicability not only for research and academic purposes, but also in a design practice. In this paper, we present a summary of our experiences in the implementation of GAMLSS to non-stationary flood frequency analysis, highlighting its advantages and pointing out weaknesses with regard to methodological and practical topics.

Damage detection of engine bladed-disks using multivariate statistical analysis

NASA Astrophysics Data System (ADS)

Fang, X.; Tang, J.

2006-03-01

The timely detection of damage in aero-engine bladed-disks is an extremely important and challenging research topic. Bladed-disks have high modal density and, particularly, their vibration responses are subject to significant uncertainties due to manufacturing tolerance (blade-to-blade difference or mistuning), operating condition change and sensor noise. In this study, we present a new methodology for the on-line damage detection of engine bladed-disks using their vibratory responses during spin-up or spin-down operations which can be measured by blade-tip-timing sensing technique. We apply a principle component analysis (PCA)-based approach for data compression, feature extraction, and denoising. The non-model based damage detection is achieved by analyzing the change between response features of the healthy structure and of the damaged one. We facilitate such comparison by incorporating the Hotelling's statistic T2 analysis, which yields damage declaration with a given confidence level. The effectiveness of the method is demonstrated by case studies.

Are Social Networking Sites Making Health Behavior Change Interventions More Effective? A Meta-Analytic Review.

PubMed

Yang, Qinghua

2017-03-01

The increasing popularity of social networking sites (SNSs) has drawn scholarly attention in recent years, and a large amount of efforts have been made in applying SNSs to health behavior change interventions. However, these interventions showed mixed results, with a large variance of effect sizes in Cohen's d ranging from -1.17 to 1.28. To provide a better understanding of SNS-based interventions' effectiveness, a meta-analysis of 21 studies examining the effects of health interventions using SNS was conducted. Results indicated that health behavior change interventions using SNS are effective in general, but the effects were moderated by health topic, methodological features, and participant features. Theoretical and practical implications of findings are discussed.

The “Task B problem” and other considerations in developmental functional neuroimaging

PubMed Central

Church, Jessica A.; Petersen, Steven E.; Schlaggar, Bradley L.

2012-01-01

Functional neuroimaging provides a remarkable tool to allow us to study cognition across the lifespan and in special populations in a safe way. However, experimenters face a number of methodological issues, and these issues are particularly pertinent when imaging children. This brief article discusses assessing task performance, strategies for dealing with group performance differences, controlling for movement, statistical power, proper atlas registration, and data analysis strategies. In addition, there will be discussion of two other topics that have important implications for interpreting fMRI data: the question of whether functional neuroanatomical differences between adults and children are the consequence of putative developmental neurovascular differences, and the issue of interpreting negative blood oxygenation-level dependent (BOLD) signal change. PMID:20496376

Gentamicin pharmacokinetics in the chicken inner ear.

PubMed

Bunting, Eric C; Park, Debra L; Durham, Dianne; Girod, Douglas A

2004-06-01

Avians have the unique ability to regenerate cochlear hair cells that are lost due to ototoxins or excessive noise. Many methodological techniques are available to damage the hair cells for subsequent scientific study. A recent method utilizes topical application of an ototoxic drug to the round window membrane. The current study examines the pharmacokinetics of gentamicin in the inner ear of chickens following topical application to the round window membrane or a single systemic high dose given intraperitoneally. Chickens were given gentamicin topically or systemically and survived for 1, 4, 12, 24, or 120 h (controls at 4 and 120 h). Serum and perilymph samples were obtained prior to sacrifice and measured for gentamicin levels. Results revealed higher levels of gentamicin in the perilymph of topically treated chickens than systemically treated chickens, with significant amounts of gentamicin still present in both at the latest survival time of 5 days. As expected, systemically treated chickens had much higher levels of gentamicin in the serum than topically treated chickens. Advantages and disadvantages to each method of drug administration are discussed.

Future perspectives on space psychology: Recommendations on psychosocial and neurobehavioural aspects of human spaceflight

NASA Astrophysics Data System (ADS)

De La Torre, Gabriel G.; van Baarsen, Berna; Ferlazzo, Fabio; Kanas, Nick; Weiss, Karine; Schneider, Stefan; Whiteley, Iya

2012-12-01

Recently the psychological effects of space flight have gained in attention. In uncovering the psychological challenges that individuals and teams can face, we need research options that integrate psychosocial aspects with behavioral, performance, technical and environmental issues. Future perspectives in Space Psychology and Human Spaceflight are reviewed in this paper. The topics covered include psychosocial and neurobehavioural aspects, neurocognitive testing tools, decision making, autonomy and delayed communications, well being, mental health, situational awareness, and methodology. Authors were members of a European Space Agency (ESA) Research Topical Team on Psychosocial and Behavioral Aspects of Human Spaceflight. They discuss the different topics under a common perspective of a theoretical and practical framework, showing interactions, relationships and possible solutions for the different aspects and variables in play. Recommendations for every topic are offered and summarized for future research in the field. The different proposed research ideas can be accomplished using analogs and simulation experiments, short- and long-duration bed rest, and in-flight microgravity studies. These topics are especially important for future Moon and Mars mission design and training.

Aeroaging - A New Collaboration between Life Sciences Experts and Aerospace Engineers.

PubMed

Vellas, M; Fualdes, C; Morley, J E; Dray, C; Rodriguez-Manas, L; Meyer, A; Michel, L; Rolland, Y; Gourinat, Y

2017-01-01

An open discussion between experts from life sciences and aeronautics has been held in order to investigate how both area of research overlap and could be relevant to each other, precisely on the topic of aging. Similarities in aging processes and prediction methodologies have been identified between human aging and aircraft aging. Two axis of collaboration have been raised: 1) The identification of the determinants in Aircraft aging (structural aging). 2) The development of P4 Systems medicine inspired new methodologies in the predictive maintenance.

Analytical aspects of plant metabolite profiling platforms: current standings and future aims.

PubMed

Seger, Christoph; Sturm, Sonja

2007-02-01

Over the past years, metabolic profiling has been established as a comprehensive systems biology tool. Mass spectrometry or NMR spectroscopy-based technology platforms combined with unsupervised or supervised multivariate statistical methodologies allow a deep insight into the complex metabolite patterns of plant-derived samples. Within this review, we provide a thorough introduction to the analytical hard- and software requirements of metabolic profiling platforms. Methodological limitations are addressed, and the metabolic profiling workflow is exemplified by summarizing recent applications ranging from model systems to more applied topics.

An overview of key technology thrusts at Bell Helicopter Textron

NASA Technical Reports Server (NTRS)

Harse, James H.; Yen, Jing G.; Taylor, Rodney S.

1988-01-01

Insight is provided into several key technologies at Bell. Specific topics include the results of ongoing research and development in advanced rotors, methodology development, and new configurations. The discussion on advanced rotors highlight developments on the composite, bearingless rotor, including the development and testing of full scale flight hardware as well as some of the design support analyses and verification testing. The discussion on methodology development concentrates on analytical development in aeromechanics, including correlation studies and design application. New configurations, presents the results of some advanced configuration studies including hardware development.

Priority gaps and promising areas in maternal health research in low- and middle-income countries: summary findings of a mapping of 2292 publications between 2000 and 2012.

PubMed

Chersich, Matthew F; Martin, Greg

2017-02-02

This commentary sums the findings of a series of papers on a study that mapped the global research agenda for maternal health. The mapping reviewed published interventional research across low- and middle-income countries (LMICs) from 2000 to 2012, specifically focusing on investigating the topics covered by this research, the methodologies applied, the funding landscape and trends in authorship attribution.The overarching aim underpinning the mapping activities was to evaluate whether research and funding align with causes of maternal mortality, and thereby highlight gaps in research priorities and governance. Fifteen reviewers from 8 countries screened 35,078 titles and abstracts, and extracted data from 2292 full-text articles.Over the period reviewed, the volume of publications rose several-fold, especially from 2004 to 2007. The methodologies broadened, increasingly encompassing qualitative research and systematic review. Malaria and HIV research dominated over other topics, while sexually-transmitted infection research progressively diminished. Health systems and health promotion research increased rapidly, but were less frequently evaluated in trials or published in high-impact journals. Relative to disease burden, hypertension had double the publications of haemorrhage. Many Latin American countries, China and Russia had relatively few papers per billion US dollars Gross Domestic Product. Total LMIC lead authorships rose substantially, but only a quarter of countries had a local first author lead on >75% of their research, with levels lowest in sub-Saharan Africa. The median Impact Factor of high-income country led papers was 3.1 and LMIC-led 1.8. The NIH, USAID and Gates Foundation constituted 40% of funder acknowledgements, and addressed similar topics and countries.The commentary notes that increases in outputs and broadening of methodologies suggest research capacity has expanded considerably, allowing for more nuanced, systems-based and context-specific studies. However, funders seemingly duplicate efforts, with topics and countries either receiving excessive or little attention. Better coordinated funding might reduce duplication and allow researchers to develop highly-specialised expertise. Repeated scrutiny of research agendas and funding may foment shifts in priorities. Building leadership capacity in LMICs and reconsidering authorship guidelines is needed.

A Learner-led, Discussion-based Elective on Emerging Infectious Disease

PubMed Central

2015-01-01

Objective. To implement a learner-led, discussion-based course aimed at exposing second-year pharmacy learners to the study of emerging infectious diseases from a global health perspective and to assess the role and importance of pharmacists in the management of disease outbreaks. Design. Learners examined literature pertinent to an emerging infectious disease in a 3-credit, discussion-based course and participated in peer discussion led by a designated learner. Instructional materials included journal articles, audio-visual presentations, documentaries, book chapters, movies, newspaper/magazine articles, and other materials. Learning outcomes were measured based on the ability of learners to perform critical thinking and analysis, communicate with their peers, and participate in class discussions. Assessment. The course was offered to 2 consecutive cohorts consisting of 14 and 16 learners, respectively. Overall, every learner in the first cohort achieved a final grade of A for the course. In the second cohort, the overall grade distribution consisted of grades of A, B, and C for the course. Learner evaluations indicated that the active-learning, discussion-based environment significantly enhanced interest in the topic and overall performance in the course. Conclusion. The elective course on emerging infectious diseases provided in-depth exposure to disease topics normally not encountered in the pharmacy curriculum. Learners found the material and format valuable, and the course enhanced their appreciation of infectious diseases, research methodology, critical thinking and analysis, and their roles as pharmacists. PMID:26430268

Citation classics in nursing journals: the top 50 most frequently cited articles from 1956 to 2011.

PubMed

Wong, Eliza L Y; Tam, Wilson W S; Wong, Faye C Y; Cheung, Annie W L

2013-01-01

Assessing the impact of individual journal articles provides information for understanding trends in science and translation of findings on practice. Citation analysis is an important way to highlight the contributions of individual author/investigator and journals on nursing practice. The purpose of this study was to identify the most frequently cited articles published in nursing journals from 1956 to 2011. The Science Citation Index Expanded and Social Sciences Citation Index were searched for citations through 2011 to articles published in the 89 nursing journals listed on the Journal Citation Reports (2010 edition). The number of citations, topic, countries, and institutions of origin based on the first author affiliation, year of publication, study design, publishing journal, journal country, and journal impact factor were noted. The most frequently cited articles published in the 89 nursing journals from 1956 to 2011 were identified. The top 50 most frequently cited articles were published in 10 nursing journals between 1970 and 2005. The top cited article received 784 citations. The most common topics were methodology for qualitative studies, validation procedures for tool development, and nursing care and practices in cancer and mental health. The most common study designs were reviews including meta-analysis and instrument validation. Most of the top 50 cited articles were published from 1986 to 1995. The findings provide insights into priorities and trends in nursing research and translational science.

A Learner-led, Discussion-based Elective on Emerging Infectious Disease.

PubMed

Mathias, Clinton

2015-08-25

Objective. To implement a learner-led, discussion-based course aimed at exposing second-year pharmacy learners to the study of emerging infectious diseases from a global health perspective and to assess the role and importance of pharmacists in the management of disease outbreaks. Design. Learners examined literature pertinent to an emerging infectious disease in a 3-credit, discussion-based course and participated in peer discussion led by a designated learner. Instructional materials included journal articles, audio-visual presentations, documentaries, book chapters, movies, newspaper/magazine articles, and other materials. Learning outcomes were measured based on the ability of learners to perform critical thinking and analysis, communicate with their peers, and participate in class discussions. Assessment. The course was offered to 2 consecutive cohorts consisting of 14 and 16 learners, respectively. Overall, every learner in the first cohort achieved a final grade of A for the course. In the second cohort, the overall grade distribution consisted of grades of A, B, and C for the course. Learner evaluations indicated that the active-learning, discussion-based environment significantly enhanced interest in the topic and overall performance in the course. Conclusion. The elective course on emerging infectious diseases provided in-depth exposure to disease topics normally not encountered in the pharmacy curriculum. Learners found the material and format valuable, and the course enhanced their appreciation of infectious diseases, research methodology, critical thinking and analysis, and their roles as pharmacists.

Political Socialization: A Topical Bibliography

ERIC Educational Resources Information Center

Brauen, Marsha; Harmon, Kathryn Newcomer

1977-01-01

Identifies four major areas of recent investigations: cross-cultural studies of political socialization, the focus on the interactive nature of the individual in the process of learning about politics, the need to examine the comparative impacts of the various agencies of political socialization, and methodological and conceptual refinements.…

34 CFR 660.34 - What priorities may the Secretary establish?

Code of Federal Regulations, 2010 CFR

2010-07-01

... or Latin America, or the languages of those regions. (3) Topics of research and studies; for example, language acquisition processes, methodology of foreign language instruction, foreign language performance... described in § 660.10. (2) Specific languages or regions for study or materials development; for example...

Higher Education for Sustainable Development: A Systematic Review

ERIC Educational Resources Information Center

Wu, Yen-Chun Jim; Shen, Ju-Peng

2016-01-01

Purpose: This study aims to provide a complete understanding of academic research into higher education for sustainable development (HESD). Design/methodology/approach: This study utilizes a systematic review of four scientific literature databases to outline topics of research during the UN's Decade of Education for Sustainable Development…

Enrichment 2.0 Gifted and Talented Education for the 21st Century

ERIC Educational Resources Information Center

Eckstein, Michelle

2009-01-01

Enrichment clusters, a component of the Schoolwide Enrichment Model, are multigrade investigative groups based on constructivist learning methodology. Enrichment clusters are organized around major disciplines, interdisciplinary themes, or cross-disciplinary topics. Within clusters, students are grouped across grade levels by interests and focused…

Childhood Asthma and Student Performance at School

ERIC Educational Resources Information Center

Taras, Howard; Potts-Datema, William

2005-01-01

To better understand what is known about the association between childhood asthma, school attendance, and academic outcomes, the authors reviewed published studies investigating this topic. Tables with brief descriptions of each study's research methodology and outcomes are included. Research reveals evidence that rates of absenteeism are higher…

Cognitive and Behavioral Components of Expertise in Teaching Physical Education.

ERIC Educational Resources Information Center

Dodds, Patt

1994-01-01

Synthesizes research on teaching expertise from physical education and other fields, offering two examples of expertise-related topics in physical education (the importance of personal performance skills and observational skills). The paper discusses cognitive, behavioral, and mixed indicators of expertise. Methodological problems in undertaking…

Overview of hypersonic CFD code calibration studies

NASA Technical Reports Server (NTRS)

Miller, Charles G.

1987-01-01

The topics are presented in viewgraph form and include the following: definitions of computational fluid dynamics (CFD) code validation; climate in hypersonics and LaRC when first 'designed' CFD code calibration studied was initiated; methodology from the experimentalist's perspective; hypersonic facilities; measurement techniques; and CFD code calibration studies.

Psychological Adjustment and Homosexuality.

ERIC Educational Resources Information Center

Gonsiorek, John C.

In this paper, the diverse literature bearing on the topic of homosexuality and psychological adjustment is critically reviewed and synthesized. The first chapter discusses the most crucial methodological issue in this area, the problem of sampling. The kinds of samples used to date are critically examined, and some suggestions for improved…

Cross-Cultural Psychology as a Scholarly Discipline: On the Flowering of Culture in Behavioral Research.

ERIC Educational Resources Information Center

Segall, Marshall H.; Lonner, Walter J.; Berry, John W.

1998-01-01

Examines interrelationship of culture and behavior. Perspectives include absolutism and relativism, each with methodological consequences for such research concerns as values gender differences, cognition, aggression, intergroup relations, and psychological acculturation. Describes societal concerns relating to these topics. Contains 88…

TEANGA: Journal of the Irish Association for Applied Linguistics, 1979-1993.

ERIC Educational Resources Information Center

O'Baoill, Donall P., Ed.

1993-01-01

This document consists of a complete run of the thirteen issues of "TEANGA" published since its inception in 1979 through 1993. Typical article topics include: linguistic research approaches and methodology; interlanguage, language transfer, and interference; second language instruction; language testing; language variation; discussion…

[Characteristics of the scientific publications on the family care provided by immigrant women].

PubMed

Casado-Mejía, Rosa; Ruiz-Arias, Esperanza; Solano-Parés, Ana

2009-01-01

To quantify and characterize the scientific production on the family care provided by immigrant women. A literature search was performed in April 2008 with no date limits in the main national and international databases: Web of Science, Current Contents Connect, ISI Proceedings, MedLine, CINAHL, PsycoInfo, EMBASE, IME, ISOC and CUIDEN. Summaries were reviewed by excluding those that did not relate to the subject of this study and those that were not in English, French or Spanish. The references of all included articles were also reviewed to detect other relevant publications. Several variables were identified and analyzed: type of article, main topic, country of the first author, and year of publication. A content analysis was performed, using the topics as categories. A total of 191 articles were retrieved and 178 were excluded. The 13 included articles analyzed differences in formal and informal care (2), determinant factors (4), epistemological needs (3), the benefits of this kind of care (5), the need for health education/training (4), the need for political/institutional support (2), immigration and health (6), and the carer/cared for relationship (4). There were five non-systematic reviews, six descriptive studies, one qualitative study and one experience. Two articles were published before 2002, eight between 2003-2005, and three between 2006-2008. Most of the studies were performed in Spain (9/13). The scarcity of articles confirms that recruitment of immigrants as caregivers is a new and invisible reality. Most of these studies highlight the benefits of this type of care. There is no dominant pattern of topics and the methodology varies widely. The few analytical studies may indicate that this topic is only beginning to be researched. Investigation into this form of care should be stimulated.

Interprofessional team debriefings with or without an instructor after a simulated crisis scenario: An exploratory case study.

PubMed

Boet, Sylvain; Pigford, Ashlee-Ann; Fitzsimmons, Amber; Reeves, Scott; Triby, Emmanuel; Bould, M Dylan

2016-11-01

The value of debriefing after an interprofessional simulated crisis is widely recognised; however, little is known about the content of debriefings and topics that prompt reflection. This study aimed to describe the content and topics that facilitate reflection among learners in two types of interprofessional team debriefings (with or without an instructor) following simulated practice. Interprofessional operating room (OR) teams (one anaesthesia trainee, one surgical trainee, and one staff circulating OR nurse) managed a simulated crisis scenario and were randomised to one of two debriefing groups. Within-team groups used low-level facilitation (i.e., no instructor but a one-page debriefing form based on the Ottawa Global Rating Scale). The instructor-led group used high-level facilitation (i.e., gold standard instructor-led debriefing). All debriefings were recorded, transcribed, and thematically analysed using the inductive qualitative methodology. Thirty-seven interprofessional team-debriefing sessions were included in the analysis. Regardless of group allocation (within-team or instructor-led), the debriefings centred on targeted crisis resource management (CRM) content (i.e., communication, leadership, situation awareness, roles, and responsibilities). In both types of debriefings, three themes emerged as topics for entry points into reflection: (1) the process of the debriefing itself, (2) experience of the simulation model, including simulation fidelity, and (3) perceived performance, including the assessment of CRM. Either with or without an instructor, interprofessional teams focused their debriefing discussion on targeted CRM content. We report topics that allowed learners to enter reflection. This is important for understanding how to maximise learning opportunities when creating education activities for healthcare providers that work in interprofessional settings.

Alternatives for jet engine control

NASA Technical Reports Server (NTRS)

Sain, M. K.

1981-01-01

Research centered on basic topics in the modeling and feedback control of nonlinear dynamical systems is reported. Of special interest were the following topics: (1) the role of series descriptions, especially insofar as they relate to questions of scheduling, in the control of gas turbine engines; (2) the use of algebraic tensor theory as a technique for parameterizing such descriptions; (3) the relationship between tensor methodology and other parts of the nonlinear literature; (4) the improvement of interactive methods for parameter selection within a tensor viewpoint; and (5) study of feedback gain representation as a counterpart to these modeling and parameterization ideas.

Analyzing the field of bioinformatics with the multi-faceted topic modeling technique.

PubMed

Heo, Go Eun; Kang, Keun Young; Song, Min; Lee, Jeong-Hoon

2017-05-31

Bioinformatics is an interdisciplinary field at the intersection of molecular biology and computing technology. To characterize the field as convergent domain, researchers have used bibliometrics, augmented with text-mining techniques for content analysis. In previous studies, Latent Dirichlet Allocation (LDA) was the most representative topic modeling technique for identifying topic structure of subject areas. However, as opposed to revealing the topic structure in relation to metadata such as authors, publication date, and journals, LDA only displays the simple topic structure. In this paper, we adopt the Tang et al.'s Author-Conference-Topic (ACT) model to study the field of bioinformatics from the perspective of keyphrases, authors, and journals. The ACT model is capable of incorporating the paper, author, and conference into the topic distribution simultaneously. To obtain more meaningful results, we use journals and keyphrases instead of conferences and bag-of-words.. For analysis, we use PubMed to collected forty-six bioinformatics journals from the MEDLINE database. We conducted time series topic analysis over four periods from 1996 to 2015 to further examine the interdisciplinary nature of bioinformatics. We analyze the ACT Model results in each period. Additionally, for further integrated analysis, we conduct a time series analysis among the top-ranked keyphrases, journals, and authors according to their frequency. We also examine the patterns in the top journals by simultaneously identifying the topical probability in each period, as well as the top authors and keyphrases. The results indicate that in recent years diversified topics have become more prevalent and convergent topics have become more clearly represented. The results of our analysis implies that overtime the field of bioinformatics becomes more interdisciplinary where there is a steady increase in peripheral fields such as conceptual, mathematical, and system biology. These results are confirmed by integrated analysis of topic distribution as well as top ranked keyphrases, authors, and journals.

The Topic Analysis of Hospice Care Research Using Co-word Analysis and GHSOM

NASA Astrophysics Data System (ADS)

Yang, Yu-Hsiang; Bhikshu, Huimin; Tsaih, Rua-Huan

The purpose of this study was to propose a multi-layer topic map analysis of palliative care research using co-word analysis of informetrics with Growing Hierarchical Self-Organizing Map (GHSOM). The topic map illustrated the delicate intertwining of subject areas and provided a more explicit illustration of the concepts within each subject area. We applied GHSOM, a text-mining Neural Networks tool, to obtain a hierarchical topic map. The result of the topic map may indicate that the subject area of health care science and service played an importance role in multidiscipline within the research related to palliative care.

Q-Sample Construction: A Critical Step for a Q-Methodological Study.

PubMed

Paige, Jane B; Morin, Karen H

2016-01-01

Q-sample construction is a critical step in Q-methodological studies. Prior to conducting Q-studies, researchers start with a population of opinion statements (concourse) on a particular topic of interest from which a sample is drawn. These sampled statements are known as the Q-sample. Although literature exists on methodological processes to conduct Q-methodological studies, limited guidance exists on the practical steps to reduce the population of statements to a Q-sample. A case exemplar illustrates the steps to construct a Q-sample in preparation for a study that explored perspectives nurse educators and nursing students hold about simulation design. Experts in simulation and Q-methodology evaluated the Q-sample for readability, clarity, and for representativeness of opinions contained within the concourse. The Q-sample was piloted and feedback resulted in statement refinement. Researchers especially those undertaking Q-method studies for the first time may benefit from the practical considerations to construct a Q-sample offered in this article. © The Author(s) 2014.

Measuring persistence: A literature review focusing on methodological issues

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wolfe, A.K.; Brown, M.A.; Trumble, D.

1995-03-01

This literature review was conducted as part of a larger project to produce a handbook on the measurement of persistence. The past decade has marked the development of the concept of persistence and a growing recognition that the long-term impacts of demand-side management (DSM) programs warrant careful assessment. Although Increasing attention has been paid to the topic of persistence, no clear consensus has emerged either about its definition or about the methods most appropriate for its measurement and analysis. This project strives to fill that gap by reviewing the goals, terminology, and methods of past persistence studies. It was conductedmore » from the perspective of a utility that seeks to acquire demand-side resources and is interested in their long-term durability; it was not conducted from the perspective of the individual consumer. Over 30 persistence studies, articles, and protocols were examined for this report. The review begins by discussing the underpinnings of persistence studies: namely, the definitions of persistence and the purposes of persistence studies. Then. it describes issues relevant to both the collection and analysis of data on the persistence of energy and demand savings. Findings from persistence studies also are summarized. Throughout the review, four studies are used repeatedly to illustrate different methodological and analytical approaches to persistence so that readers can track the data collection. data analysis, and findings of a set of comprehensive studies that represent alternative approaches.« less

Rotorcraft noise

NASA Technical Reports Server (NTRS)

Huston, R. J. (Compiler)

1982-01-01

The establishment of a realistic plan for NASA and the U.S. helicopter industry to develop a design-for-noise methodology, including plans for the identification and development of promising noise reduction technology was discussed. Topics included: noise reduction techniques, scaling laws, empirical noise prediction, psychoacoustics, and methods of developing and validing noise prediction methods.

Topics in Chemical Instrumentation--An Introduction to Supercritical Fluid Chromatography: Part 1: Principles and Instrumentation.

ERIC Educational Resources Information Center

Palmieri, Margo D.

1988-01-01

Identifies the properties and characteristics of supercritical fluids. Discusses the methodology for supercritical fluid chromatography including flow rate, plate height, column efficiency, viscosity, and other factors. Reviews instruments, column types, and elution conditions. Lists supercritical fluid data for 22 compounds, mostly organic. (MVL)

75 FR 69094 - Solicitation for Nominations for Members of the U.S. Preventive Services Task Force (USPSTF)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-10

... final recommendation documents, and participating in workgroups on specific topics or methods. A... literature and in the methods of evidence review; 2. Understanding and experience in the application of... based on their expertise in methodological issues such as medical decisionmaking, clinical epidemiology...

Large-Scale Networked Virtual Environments: Architecture and Applications

ERIC Educational Resources Information Center

Lamotte, Wim; Quax, Peter; Flerackers, Eddy

2008-01-01

Purpose: Scalability is an important research topic in the context of networked virtual environments (NVEs). This paper aims to describe the ALVIC (Architecture for Large-scale Virtual Interactive Communities) approach to NVE scalability. Design/methodology/approach: The setup and results from two case studies are shown: a 3-D learning environment…

75 FR 54403 - U.S. National Climate Assessment Objectives, Proposed Topics, and Next Steps

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-07

..., methods and design, tools for assessing climate change and impacts, dealing with uncertainty, sources of..., coordination with other Federal climate-related programs, design of documents and tailored communications with... methodological perspectives related to selecting model and downscaling outputs and approaches for their use in...

76 FR 74785 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-01

..., as it will generate methodological evidence through a randomized controlled experiment comparing five... is designed to improve upon the sometimes superficial or ``top of mind'' responses that are often...--Educational materials are designed to inform participants about the topics that are being deliberated and will...

Screen Layout Design: Research into the Overall Appearance of the Screen.

ERIC Educational Resources Information Center

Grabinger, R. Scott

1989-01-01

Examines the current state of research into the visual effects of screen designs used in computer-assisted instruction and suggests areas for future efforts. Topics discussed include technical elements and comprehensibility elements in layout design; single element and multiple element research methodologies; dependent variables; and learning…

Interdisciplinarity in Education: Overcoming Fragmentation in the Teaching-Learning Process

ERIC Educational Resources Information Center

Santos, Carla Madalena; Franco, Rubia Amanda; Leon, Diego; Ovigli, Daniel Bovolenta; Donizete Colombo, Pedro, Jr.

2017-01-01

The importance of interdisciplinarity in the teaching-learning process has been much debated. This topic has challenged schoolteachers, who do not always manage to integrate interdisciplinarity into the school routine. This paper emerged from the discipline Research Methodology taught at the postgraduate course in education of Universidade Federal…

Preventing Youth Pregnancy: Dialogue and Deliberation in a Science Museum Exhibit

ERIC Educational Resources Information Center

Navas-Iannini, Ana Maria; Pedretti, Erminia

2017-01-01

In this article, we explore how visitors engage with a science museum exhibit that displays controversial topics. Through a case study methodology, we focus on the Brazilian exhibit "Preventing Youth Pregnancy" that delves into teen pregnancy, sexual practices, and sexually transmitted diseases. Using the lens of science communication…

Combining Formal and Functional Approaches to Topic Structure

ERIC Educational Resources Information Center

Zellers, Margaret; Post, Brechtje

2012-01-01

Fragmentation between formal and functional approaches to prosodic variation is an ongoing problem in linguistic research. In particular, the frameworks of the Phonetics of Talk-in-Interaction (PTI) and Empirical Phonology (EP) take very different theoretical and methodological approaches to this kind of variation. We argue that it is fruitful to…

Coaching to Enhance Quality of Implementation in Prevention

ERIC Educational Resources Information Center

Dusenbury, Linda; Hansen, William B.; Jackson-Newsom, Julia; Pittman, Donna S.; Wilson, Cicely V.; Nelson-Simley, Kathleen; Ringwalt, Chris; Pankratz, Melinda; Giles, Steven M.

2010-01-01

Purpose: The purpose of this paper is to describe the topics covered by coaches assisting teachers implementing a research-based drug prevention program and explore how coaching affects student outcomes. Design/methodology/approach: The All Stars drug prevention curriculum is implemented by 16 urban teachers who received four coaching sessions.…

"Picturing" Lay Ministry: Photovoice and Participatory Group Spiritual Gifts Assessment

ERIC Educational Resources Information Center

Trefz, Steven G.

2013-01-01

The "Picturing Lay Ministry" project uses the visual methodology of photovoice as a way of generating participatory laity discernment around the topics of calling, rural ministry, and spiritual gifts. The project involves working with curriculum action research embedded within one-day ministry discernment events for laity. Measurement…

Sports Medicine in China.

ERIC Educational Resources Information Center

Bloomquist, Lorraine E.

This report on a visit to the People's Republic of China in April 1985 to explore methodology of sports science research, treatment of injuries, and role of sports in everyday life discusses the following topics: (1) introduction to China; (2) sports and physical culture; (3) sports medicine and rehabilitation; (4) health factors; (5) cost of…

Lean and Agile: An Epistemological Reflection

ERIC Educational Resources Information Center

Browaeys, Marie-Joelle; Fisser, Sandra

2012-01-01

Purpose: The aim of the paper is to contribute to the discussion of treating the concepts of lean and agile in isolation or combination by presenting an alternative view from complexity thinking on these concepts, considering an epistemological approach to this topic. Design/methodology/approach: The paper adopts an epistemological approach, using…

Organisational and Training Factors Affecting Academic Teacher Training Outcomes

ERIC Educational Resources Information Center

Renta-Davids, Ana-Inés; Jiménez-González, José-Miguel; Fandos-Garrido, Manel; González-Soto, Ángel-Pío

2016-01-01

University teacher training has become an important topic in recent years due to the curricular and methodological reforms introduced by the Bologna process. Despite its acknowledged importance, evaluations have been limited to measures of participants' satisfaction, and little is known about its impact on teaching practices. This study seeks to…

Microbiology--Detection, Occurrence, and Removal of Viruses.

ERIC Educational Resources Information Center

Berg, Gerald

1978-01-01

Presents a literature review of the detection, survival, and destruction of viruses in wastewater sludges, covering publications of 1976-77. This review includes these topics: (1) detection methodology; (2) viruses in sludge, shellfish, and aerosols; and (3) indicators of viruses. A list of 59 references is also presented. (HM)

Topic Centred Subject/Language Learning Materials and Their Use.

ERIC Educational Resources Information Center

Rado, Marta

Social bilinguals (second language learners in a linguistic minority) and cultural bilinguals (foreign language learners) often learn side by side in the same classroom, making syllabus planning and choice of teaching methodology difficult. Adopting a bilingual approach and exploring the semantic and discourse aspects of language can overcome the…

Science Education Research vs. Physics Education Research: A Structural Comparison

ERIC Educational Resources Information Center

Akarsu, Bayram

2010-01-01

The main goal of this article is to introduce physics education research (PER) to researchers in other fields. Topics include discussion of differences between science education research (SER) and physics education research (PER), physics educators, research design and methodology in physics education research and current research traditions and…

A Profile of Clinical Nutrition Knowledge Among Physicians and Medical Students

ERIC Educational Resources Information Center

Podell, Richard N.; And Others

1975-01-01

An assessment of the clinical nutritional knowledge of third- and fourth-year medical students and practicing physicians revealed that overall nutritional knowledge is modest and that knowledge is highest among topics which have received the most publicity in the popular press. Methodology and specific findings are included. (JT)

The Value of LIS Schools' Research Topics to Library Authors' Professional Work

ERIC Educational Resources Information Center

Perkins, Gay Helen; Helbig, Tuesdi L.

2008-01-01

Stoan's distinction between library skills and research skills based on different philosophies of information seeking suggests the value of training in research methodology for the librarian. Such training could lead to more effective patron consultations, committee/administrative work, and personal research. Thus, a convenience sample of…

Life-Span Developmental Psychology: Non-Normative Life Events. A Review of the Seventh West Virginia University Life-Span Developmental Psychology Conference.

ERIC Educational Resources Information Center

Richardson, Gale A.; Kwiatkowski, Bonnie M.

1981-01-01

Topics covered in this conference included parenting, terminal illness, the birth of severely disabled children, rape and family violence, separation and divorce, and hospitalization, and dealt with a wide range of methodologies and age periods. (Author/RH)

Enhancing the Ties that Bind: Mentoring as a Moderator

ERIC Educational Resources Information Center

Dawley, David. D.; Andrews, Martha C.; Bucklew, Neil S.

2010-01-01

Purpose: The purpose of this paper is to examine the moderating role of mentoring on the relationships between perceived organizational support, supervisor support, and job fit on turnover intentions. Design/methodology/approach: The paper explains the topics, provides background and discussion of the main concepts. The study uses regression…

Managing Family Conflict over Career Decisions: The Experience of Asian Americans

ERIC Educational Resources Information Center

Ma, Pei-Wen Winnie; Desai, Uttara; George, Login S.; San Filippo, Alyssa A.; Varon, Samantha

2014-01-01

Conflict over career decisions is a main source of intergenerational conflict among Asian American families. This qualitative study explored the topic using consensual qualitative research methodology in a sample of eight Asian Americans. Results indicated that participants experienced feelings of guilt and indebtedness due to conflicting values,…

Adjustment to Widowhood and Divorce: A Review.

ERIC Educational Resources Information Center

Kitson, Gay C.; And Others

1989-01-01

Examines studies of adjustment to widowhood and/or divorce and points out those places where findings are similar or different. Explores impact upon adjustment of cause of death or divorce, timing of event, demographic correlates, economic issues, social support, and attachment. Concludes with discussion of methodological issues and topics for…

Adulthood and Aging.

ERIC Educational Resources Information Center

Thomas, Jeanne L.

This textbook is designed to introduce undergraduates to the scientific study of aging in adults. Among the topics covered in the book's 15 chapters are: approaches to the study of adult development and aging (research methodology and related issues, a life-span perspective, ethical issues); theories in the study of adult development (models of…

Research Commentary: The Promise of Qualitative Metasynthesis for Mathematics Education

ERIC Educational Resources Information Center

Thunder, Kateri; Berry, Robert Q., III.

2016-01-01

Mathematics education has benefited from qualitative methodological approaches over the past 40 years across diverse topics. Although the number, type, and quality of qualitative research studies in mathematics education has changed, little is known about how a collective body of qualitative research findings contributes to our understanding of a…

Your Career as a Successful Independent TESL Professional

ERIC Educational Resources Information Center

Eaton, Sarah Elaine

2015-01-01

The purpose of this presentation is to present information on how to develop one's career as an independent TESOL professional (e.g. adjunct instructor, freelancer, contractor or consultant). The methodology used to present this information is active practitioner reflection. The discussion includes topics such as various types independent…

The Pragmatic Skills of Learning Disabled Children: A Review.

ERIC Educational Resources Information Center

Dudley-Marling, Curtis

1985-01-01

Studies are reviewed in four topic areas: (1) learning disabled (LD) students' spontaneous use of language; (2) their ability to adapt language to listener characteristics; (3) effectiveness of their communications; and (4) their ability to fulfill listener responsibilities. Noted are methodological flaws which cast doubt on implications for…

Reflections: Continuing the Conversation

ERIC Educational Resources Information Center

Stephenson, Maxine

2012-01-01

An overarching methodological focus in this issue of the "Journal of Educational Administration and History" has been to engage Michel Foucault's concern with "a history of the present". In this article, the author begins her overview of the collection in the present--specifically, and in keeping with the topic for this special…

Research on Divorce: Continuing Trends and New Developments

ERIC Educational Resources Information Center

Amato, Paul R.

2010-01-01

Research on divorce during the past decade has focused on a range of topics, including the predictors of divorce, associations between divorce and the well-being of children and former spouses, and interventions for divorcing couples. Methodological advances during the past decade include a greater reliance on nationally representative…

Tenth Workshop for Computational Fluid Dynamic Applications in Rocket Propulsion, part 1

NASA Technical Reports Server (NTRS)

Williams, R. W. (Compiler)

1992-01-01

Experimental and computational fluid dynamic activities in rocket propulsion were discussed. The workshop was an open meeting of government, industry, and academia. A broad number of topics were discussed including computational fluid dynamic methodology, liquid and solid rocket propulsion, turbomachinery, combustion, heat transfer, and grid generation.

SOCIAL SCIENCE EDUCATION CONSORTIUM. PUBLICATION 122, MORALITY.

ERIC Educational Resources Information Center

SCRIVEN, MICHAEL

THIS POSITION PAPER PRESENTS AN APPROACH TO THE VERY DIFFICULT PROBLEM OF HANDLING VALUES IN THE EDUCATIONAL PROCESS, PARTICULARLY IN THE PUBLIC SCHOOLS. IT DISCUSSES THE FOUNDATIONS OF ETHICS AND THE METHODOLOGICAL BASIS FOR MORAL VALUE JUDGMENTS. THE DISCUSSIONS ARE PRESENTED UNDER THREE GENERAL TOPIC AREAS--(1) "PRELIMINARIES" WHICH…

On self-propagating methodological flaws in performance normalization for strength and power sports.

PubMed

Arandjelović, Ognjen

2013-06-01

Performance in strength and power sports is greatly affected by a variety of anthropometric factors. The goal of performance normalization is to factor out the effects of confounding factors and compute a canonical (normalized) performance measure from the observed absolute performance. Performance normalization is applied in the ranking of elite athletes, as well as in the early stages of youth talent selection. Consequently, it is crucial that the process is principled and fair. The corpus of previous work on this topic, which is significant, is uniform in the methodology adopted. Performance normalization is universally reduced to a regression task: the collected performance data are used to fit a regression function that is then used to scale future performances. The present article demonstrates that this approach is fundamentally flawed. It inherently creates a bias that unfairly penalizes athletes with certain allometric characteristics, and, by virtue of its adoption in the ranking and selection of elite athletes, propagates and strengthens this bias over time. The main flaws are shown to originate in the criteria for selecting the data used for regression, as well as in the manner in which the regression model is applied in normalization. This analysis brings into light the aforesaid methodological flaws and motivates further work on the development of principled methods, the foundations of which are also laid out in this work.

Cooperative learning combined with short periods of lecturing: A good alternative in teaching biochemistry.

PubMed

Fernández-Santander, Ana

2008-01-01

The informal activities of cooperative learning and short periods of lecturing has been combined and used in the university teaching of biochemistry as part of the first year course of Optics and Optometry in the academic years 2004-2005 and 2005-2006. The lessons were previously elaborated by the teacher and included all that is necessary to understand the topic (text, figures, graphics, diagrams, pictures, etc.). Additionally, a questionnaire was prepared for every chapter. All lessons contained three parts: objectives, approach and development, and the assessment of the topic. Team work, responsibility, and communication skills were some of the abilities developed with this new methodology. Students worked collaboratively in small groups of two or three following the teacher's instructions with short periods of lecturing that clarified misunderstood concepts. Homework was minimized. On comparing this combined methodology with the traditional one (only lecture), students were found to exhibit a higher satisfaction with the new method. They were more involved in the learning process and had a better attitude toward the subject. The use of this new methodology showed a significant increase in the mean score of the students' academic results. The rate of students who failed the subject was significantly inferior in comparison with those who failed in the previous years when only lecturing was applied. This combined methodology helped the teacher to observe the apprenticeship process of students better and to act as a facilitator in the process of building students' knowledge. Copyright © 2008 International Union of Biochemistry and Molecular Biology, Inc.

Toward Consistent Methodology to Quantify Populations in Proximity to Oil and Gas Development: A National Spatial Analysis and Review.

PubMed

Czolowski, Eliza D; Santoro, Renee L; Srebotnjak, Tanja; Shonkoff, Seth B C

2017-08-23

Higher risk of exposure to environmental health hazards near oil and gas wells has spurred interest in quantifying populations that live in proximity to oil and gas development. The available studies on this topic lack consistent methodology and ignore aspects of oil and gas development of value to public health-relevant assessment and decision-making. We aim to present a methodological framework for oil and gas development proximity studies grounded in an understanding of hydrocarbon geology and development techniques. We geospatially overlay locations of active oil and gas wells in the conterminous United States and Census data to estimate the population living in proximity to hydrocarbon development at the national and state levels. We compare our methods and findings with existing proximity studies. Nationally, we estimate that 17.6 million people live within 1,600m (∼1 mi) of at least one active oil and/or gas well. Three of the eight studies overestimate populations at risk from actively producing oil and gas wells by including wells without evidence of production or drilling completion and/or using inappropriate population allocation methods. The remaining five studies, by omitting conventional wells in regions dominated by historical conventional development, significantly underestimate populations at risk. The well inventory guidelines we present provide an improved methodology for hydrocarbon proximity studies by acknowledging the importance of both conventional and unconventional well counts as well as the relative exposure risks associated with different primary production categories (e.g., oil, wet gas, dry gas) and developmental stages of wells. https://doi.org/10.1289/EHP1535.

Sensor-based activity recognition using extended belief rule-based inference methodology.

PubMed

Calzada, A; Liu, J; Nugent, C D; Wang, H; Martinez, L

2014-01-01

The recently developed extended belief rule-based inference methodology (RIMER+) recognizes the need of modeling different types of information and uncertainty that usually coexist in real environments. A home setting with sensors located in different rooms and on different appliances can be considered as a particularly relevant example of such an environment, which brings a range of challenges for sensor-based activity recognition. Although RIMER+ has been designed as a generic decision model that could be applied in a wide range of situations, this paper discusses how this methodology can be adapted to recognize human activities using binary sensors within smart environments. The evaluation of RIMER+ against other state-of-the-art classifiers in terms of accuracy, efficiency and applicability was found to be significantly relevant, specially in situations of input data incompleteness, and it demonstrates the potential of this methodology and underpins the basis to develop further research on the topic.

Topical NSAIDs for chronic musculoskeletal pain in adults

PubMed Central

Derry, Sheena; Moore, R Andrew; Rabbie, Roy

2014-01-01

Background Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly taken orally, but they are also available in topical preparations to be applied to or rubbed onto the skin of a painful joint, typically one affected by arthritis, with the aim of relieving pain locally. Topical NSAIDs are widely used in some parts of the world for acute and chronic painful conditions, but have not been universally accepted until recently. One of the problems has been that older clinical studies were generally short, lasting four weeks or less, and short duration studies are not regarded as adequate in ongoing painful conditions. Objectives To examine the use of topical NSAIDs in chronic musculoskeletal pain, focusing on studies of high methodological quality, and examining the measured effect of the preparations according to study duration. The principal aim was to estimate treatment efficacy in longer duration studies of at least 8 weeks. Search methods A series of electronic searches, together with bibliographic searches, and searches of in-house databases were combined with electronic searches of clinical trial registers and manufacturers of topical NSAIDs, or companies known to be actively researching topical NSAIDs. There had to be at least 10 participants in each treatment arm, with application of treatment at least once daily. Selection criteria Randomised, double blind studies with placebo or active comparators, where at least one treatment was a topical NSAID product, in any topical formulation (cream, gel, patch, solution), in studies lasting at least two weeks. Data collection and analysis Two review authors independently assessed study quality and validity, and extracted data. Numbers of participants achieving each outcome were used to calculate relative risk (RR) and numbers needed to treat (NNT) or harm (NNH) compared to placebo or other active treatment. Main results Information was available from 7688 participants in 34 studies from 32 publications; 23 studies compared a topical NSAID with placebo. Topical NSAIDs were significantly more effective than placebo for reducing pain due to chronic musculoskeletal conditions. The best data were for topical diclofenac in osteoarthritis, where the NNT for at least 50% pain relief over 8 to 12 weeks compared with placebo was 6.4 for the solution, and 11 for the gel formulation. There were too few data of good quality to calculate NNTs for other individual topical NSAIDs compared with placebo. Direct comparison of topical NSAID with an oral NSAID did not show any difference in efficacy. There was an increase in local adverse events (mostly mild skin reactions) with topical NSAIDs compared with placebo or oral NSAIDs, but no increase in serious adverse events. Gastrointestinal adverse events with topical NSAID did not differ from placebo, but were less frequent than with oral NSAIDs. A substantial amount of data from unpublished studies was unavailable. Much of this probably relates to formulations that have never been marketed. Authors’ conclusions Topical NSAIDs can provide good levels of pain relief; topical diclofenac solution is equivalent to that of oral NSAIDs in knee and hand osteoarthritis, but there is no evidence for other chronic painful conditions. Formulation can influence efficacy. The incidence of local adverse events is increased with topical NSAIDs, but gastrointestinal adverse events are reduced compared with oral NSAIDs. PMID:22972108

Implications of vitamin D deficiency in lithiasic patient and in general population.

PubMed

Millán-Rodríguez, F; Gavrilov, P; Gracia-García, S; Angerri-Feu, O; Sánchez-Martín, F M; Villavicencio-Mavrich, H

2015-05-01

Vitamin D deficiency causes problems in mineral metabolism but also overall health. In first place a review of the topic was carried out. Then, in order to contextualize it in lithiasic patient, a study on Vitamin D deficiency and its possible relationship with impaired PTH levels is performed. A review of topics such as metabolism, epidemiology and the relationship of vitamin D deficiency with several pathologies was performed. Besides a multivariate analysis and a correlation study between vitamin D and PTH levels was conducted in 100 lithiasic patients. We present a review of Vitamin D metabolism, receptors and functions, as well as about its valuation methodology and the treatment of its deficiency. Lithiasic patients show a higher vitamin D deficiency than general population. Vitamin D deficiency has been significantly associated with increased PTH levels. In addition, there is enough literature showing a relationship between vitamin D deficiency not only with bone disease, but also with multiple diseases. vitamin D levels should be measured in all lithiasic patients, and those with vitamin D deficiency should be treated. Copyright © 2014 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

Bibliometric study of articles published in a Brazilian journal of pediatric dentistry.

PubMed

Poletto, Vanessa Ceolin; Faraco Junior, Italo Medeiros

2010-01-01

This cross-sectional study aimed at evaluating the abstracts of all articles published in the 'Jornal Brasileiro de Odontopediatria e Odontologia do Bebê' in order to collect data on the study design used, the most researched topics and the Brazilian states with the highest scientific production. Copies were made of the abstracts of each article, totaling 572 abstracts. Data categorization was done by two trained and independent reviewers. The results showed that the most used study design were case report (33%) and cross-sectional study (30%). On the other hand, there were only 2.5% of randomized clinical trials and no systematic review or meta-analysis. The most researched topics were cariology (15%) and restorative dentistry / dental materials (10%). The state with the greatest number of publications was São Paulo (40%), followed by Rio de Janeiro (17%). It was concluded that the majority of the articles published referred to studies with a low potential to establish scientific evidence, indicating a need for conducting research based on better quality methodology. Moreover, it was found that the assessed literature reflected the trends observed in the clinical practice of Pediatric Dentistry in Brazil.

An appraisal of the quality of published qualitative dental research.

PubMed

Masood, Mohd; Thaliath, Ebin T; Bower, Elizabeth J; Newton, J Timothy

2011-06-01

To appraise the quality of published qualitative research in dentistry and identify aspects of quality, which require attention in future research. Qualitative research studies on dental topics were appraised using the critical appraisal skills programme (CASP) appraisal framework for qualitative research. The percentage of CASP criteria fully met during the assessment was used as an indication of the quality of each paper. Individual criteria were not weighted. Forty-three qualitative studies were identified for appraisal of which 48% had a dental public health focus. Deficiencies in detail of reporting, research design, methodological rigour, presentation of findings, reflexivity, credibility of findings and relevance of study were identified. Problems with quality were apparent irrespective of journal impact factor, although papers from low impact factor journals exhibited the most deficiencies. Journals with the highest impact factors published the least qualitative research. The quality of much of the qualitative research published on dental topics is mediocre. Qualitative methods are underutilized in oral health research. If quality guidelines such as the CASP framework are used in the context of a thorough understanding of qualitative research design and data analysis, they can promote good practice and the systematic assessment of qualitative research. © 2010 John Wiley & Sons A/S.

Studies analysing the need for health-related information in Germany - a systematic review.

PubMed

Pieper, Dawid; Jülich, Fabian; Antoine, Sunya-Lee; Bächle, Christina; Chernyak, Nadja; Genz, Jutta; Eikermann, Michaela; Icks, Andrea

2015-09-23

Exploring health-related information needs is necessary to better tailor information. However, there is a lack of systematic knowledge on how and in which groups information needs has been assessed, and which information needs have been identified. We aimed to assess the methodology of studies used to assess information needs, as well as the topics and extent of health-related information needs and associated factors in Germany. A systematic search was performed in Medline, Embase, Psycinfo, and all databases of the Cochrane Library. All studies investigating health-related information needs in patients, relatives, and the general population in Germany that were published between 2000 and 2012 in German or English were included. Descriptive content analysis was based on predefined categories. We identified 19 studies. Most studies addressed cancer or rheumatic disease. Methods used were highly heterogeneous. Apart from common topics such as treatment, diagnosis, prevention and health promotion, etiology and prognosis, high interest ratings were also found in more specific topics such as complementary and alternative medicine or nutrition. Information needs were notable in all surveyed patient groups, relatives, and samples of the general population. Younger age, shorter duration of illness, poorer health status and higher anxiety and depression scores appeared to be associated with higher information needs. Knowledge about information needs is still scarce. Assuming the importance of comprehensive information to enable people to participate in health-related decisions, further systematic research is required.

Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials.

PubMed

Liu, Rosemarie H; Smith, Molly K; Basta, Sameh A; Farmer, Evan R

2006-08-01

To evaluate the clinical efficacy of topical 20% azelaic acid cream and 15% azelaic acid gel compared with their respective vehicles and metronidazole gel in the treatment of papulopustular rosacea. Electronic searches of MEDLINE, EMBASE, BIOSIS, and SciSearch through July or August 2004 and the Cochrane Central Register of Controlled Trials through 2004 (issue 3). We performed hand searches of reference lists, conference proceedings, and clinical trial databases. Experts in rosacea and azelaic acid were contacted. Randomized controlled trials involving topical azelaic acid (cream or gel) for the treatment of rosacea compared with placebo or other topical treatments. Two authors independently examined the studies identified by the searches. Ten studies were identified, of which 5 were included (873 patients). Two authors independently extracted data from the included studies, then jointly assessed methodological quality using a quality assessment scale. Because standard deviation data were not available for 4 of the 5 studies, a meta-analysis could not be conducted. Four of the 5 studies demonstrated significant decreases in mean inflammatory lesion count and erythema severity after treatment with azelaic acid compared with vehicle. None of the studies showed any significant decrease in telangiectasia severity. Azelaic acid in 20% cream and 15% gel formulations appears to be effective in the treatment of papulopustular rosacea, particularly in regard to decreases in mean inflammatory lesion count and erythema severity. Compared with metronidazole, azelaic acid appears to be an equally effective, if not better, treatment option.

How a science methods course may influence the curriculum decisions of preservice teachers in the Bahamas

NASA Astrophysics Data System (ADS)

Wisdom, Sonya L.

The purpose of this study was to examine how a science methods course in primary education might influence the curriculum decisions of preservice teachers in The Bahamas related to unit plan development on environmental science topics. Grounded in a social constructivist theoretical framework for teaching and learning science, this study explored the development of the confidence and competence of six preservice teachers to teach environmental science topics at the primary school level. A qualitative case study using action research methodologies was conducted. The perspectives of preservice teachers about the relevancy of methods used in a science methods course were examined as I became more reflective about my practice. Using constant comparative analysis, data from student-written documents and interviews as well as my field notes from class observations and reflective journaling were analyzed for emerging patterns and themes. Findings of the study indicated that while preservice teachers showed a slight increase in interest regarding learning and teaching environmental science, their primary focus during the course was learning effective teaching strategies in science on topics with which they already had familiarity. Simultaneously, I gained a deeper understanding of the usefulness of reflection in my practice. As a contribution to the complexity of learning to teach science at the primary school level, this study suggests some issues for consideration as preservice teachers are supported to utilize more of the national primary science curriculum in The Bahamas.

ARAMIS project: a comprehensive methodology for the identification of reference accident scenarios in process industries.

PubMed

Delvosalle, Christian; Fievez, Cécile; Pipart, Aurore; Debray, Bruno

2006-03-31

In the frame of the Accidental Risk Assessment Methodology for Industries (ARAMIS) project, this paper aims at presenting the work carried out in the part of the project devoted to the definition of accident scenarios. This topic is a key-point in risk assessment and serves as basis for the whole risk quantification. The first result of the work is the building of a methodology for the identification of major accident hazards (MIMAH), which is carried out with the development of generic fault and event trees based on a typology of equipment and substances. The term "major accidents" must be understood as the worst accidents likely to occur on the equipment, assuming that no safety systems are installed. A second methodology, called methodology for the identification of reference accident scenarios (MIRAS) takes into account the influence of safety systems on both the frequencies and possible consequences of accidents. This methodology leads to identify more realistic accident scenarios. The reference accident scenarios are chosen with the help of a tool called "risk matrix", crossing the frequency and the consequences of accidents. This paper presents both methodologies and an application on an ethylene oxide storage.

Position statement: introduction, methods, and participants. The Writing Group for the International Society for Clinical Densitometry (ISCD) Position Development Conference.

PubMed

2004-01-01

Following publication of the proceedings from the first Position Development Conference (PDC) of the International Society for Clinical Densitometry (ISCD), members of the ISCD Scientific Advisory Committee (SAC) addressed additional topics of interest in the field of bone densitometry. These topics were addressed at a subsequent PDC, which was held in Cincinnati, Ohio, July 25-27, 2003. Five topics were chosen for discussion: (1) the diagnosis of osteoporosis in men, premenopausal women, and children; (2) technical standardization for dual-energy X-ray absorptiometry (DXA); (3) indications for bone densitometry; (4) reporting of bone density results; and (5) nomenclature and decimal places for bone densitometry. This report describes the methodology used for the development, presentation, and finalization of PDC positions. These positions are discussed in the following papers.

New insights into soil temperature time series modeling: linear or nonlinear?

NASA Astrophysics Data System (ADS)

Bonakdari, Hossein; Moeeni, Hamid; Ebtehaj, Isa; Zeynoddin, Mohammad; Mahoammadian, Abdolmajid; Gharabaghi, Bahram

2018-03-01

Soil temperature (ST) is an important dynamic parameter, whose prediction is a major research topic in various fields including agriculture because ST has a critical role in hydrological processes at the soil surface. In this study, a new linear methodology is proposed based on stochastic methods for modeling daily soil temperature (DST). With this approach, the ST series components are determined to carry out modeling and spectral analysis. The results of this process are compared with two linear methods based on seasonal standardization and seasonal differencing in terms of four DST series. The series used in this study were measured at two stations, Champaign and Springfield, at depths of 10 and 20 cm. The results indicate that in all ST series reviewed, the periodic term is the most robust among all components. According to a comparison of the three methods applied to analyze the various series components, it appears that spectral analysis combined with stochastic methods outperformed the seasonal standardization and seasonal differencing methods. In addition to comparing the proposed methodology with linear methods, the ST modeling results were compared with the two nonlinear methods in two forms: considering hydrological variables (HV) as input variables and DST modeling as a time series. In a previous study at the mentioned sites, Kim and Singh Theor Appl Climatol 118:465-479, (2014) applied the popular Multilayer Perceptron (MLP) neural network and Adaptive Neuro-Fuzzy Inference System (ANFIS) nonlinear methods and considered HV as input variables. The comparison results signify that the relative error projected in estimating DST by the proposed methodology was about 6%, while this value with MLP and ANFIS was over 15%. Moreover, MLP and ANFIS models were employed for DST time series modeling. Due to these models' relatively inferior performance to the proposed methodology, two hybrid models were implemented: the weights and membership function of MLP and ANFIS (respectively) were optimized with the particle swarm optimization (PSO) algorithm in conjunction with the wavelet transform and nonlinear methods (Wavelet-MLP & Wavelet-ANFIS). A comparison of the proposed methodology with individual and hybrid nonlinear models in predicting DST time series indicates the lowest Akaike Information Criterion (AIC) index value, which considers model simplicity and accuracy simultaneously at different depths and stations. The methodology presented in this study can thus serve as an excellent alternative to complex nonlinear methods that are normally employed to examine DST.

Frontier-based techniques in measuring hospital efficiency in Iran: a systematic review and meta-regression analysis

PubMed Central

2013-01-01

Background In recent years, there has been growing interest in measuring the efficiency of hospitals in Iran and several studies have been conducted on the topic. The main objective of this paper was to review studies in the field of hospital efficiency and examine the estimated technical efficiency (TE) of Iranian hospitals. Methods Persian and English databases were searched for studies related to measuring hospital efficiency in Iran. Ordinary least squares (OLS) regression models were applied for statistical analysis. The PRISMA guidelines were followed in the search process. Results A total of 43 efficiency scores from 29 studies were retrieved and used to approach the research question. Data envelopment analysis was the principal frontier efficiency method in the estimation of efficiency scores. The pooled estimate of mean TE was 0.846 (±0.134). There was a considerable variation in the efficiency scores between the different studies performed in Iran. There were no differences in efficiency scores between data envelopment analysis (DEA) and stochastic frontier analysis (SFA) techniques. The reviewed studies are generally similar and suffer from similar methodological deficiencies, such as no adjustment for case mix and quality of care differences. The results of OLS regression revealed that studies that included more variables and more heterogeneous hospitals generally reported higher TE. Larger sample size was associated with reporting lower TE. Conclusions The features of frontier-based techniques had a profound impact on the efficiency scores among Iranian hospital studies. These studies suffer from major methodological deficiencies and were of sub-optimal quality, limiting their validity and reliability. It is suggested that improving data collection and processing in Iranian hospital databases may have a substantial impact on promoting the quality of research in this field. PMID:23945011

A systematic literature review on the application of Rasch analysis in musculoskeletal disease -- a special interest group report of OMERACT 11.

PubMed

Leung, Ying-Ying; Png, May-Ee; Conaghan, Philip; Tennant, Alan

2014-01-01

The Rasch measurement model provides robust analysis of the internal construct validity of outcome measures. We reviewed the application of Rasch analysis in musculoskeletal medicine as part of the work leading to discussion in a Special Interest Group in Rasch Analysis at Outcome Measures in Rheumatology 11. A systematic literature review of SCOPUS and MEDLINE was performed (January 1, 1985, to February 29, 2012. Original research reports in English using "Rasch" or "Item Response Theory" in musculoskeletal diseases were assessed by 2 independent reviewers. The topics of focus and analysis methodology details were recorded. Of 212 articles reviewed, 114 were included. The number of publications rose from 1 in 1991-1992 to 23 in 2011-February 2012. Disease areas included rheumatoid arthritis (28%), osteoarthritis (16.6%), and general musculoskeletal disorders (43%). Sixty-six reports (57.9%) evaluated psychometric properties of existing scales and 35 (30.7%) involved development of new scales. Nine articles (7.9%) were on methodology illustration. Four articles were on item banking and computer adaptive testing. A majority of the articles reported fit statistics, while the basic Rasch model assumption (i.e., unidimensionality) was examined in only 57.2% of the articles. An improvement in reporting qualities with Rasch articles was noted over time. In addition, only 11.4% of the articles provided a transformation table for interval scale measurement in clinical practice. The Rasch model has been increasingly used in rheumatology over the last 2 decades in a wide range of applications. The majority of the articles demonstrated reasonable quality of reporting. Improvements in quality of reporting over time were revealed.

[Public access to information about the services and quality of care in public hospitals: the need for methodologic clarity. A survey of 44 university hospital directors and administrators].

PubMed

Vallet, Guy; Perrin, Anne; Keller, Christiane; Fieschi, Marius

2006-03-01

For the past eight years, the Ministry of Health has released information about the services and quality of care in public hospitals, in response to the increasing concern about hospital performance expressed by patient associations. The press publishes hospital ratings based on this information. This survey asked hospital administrators about their views of communication on this topic. This survey, conducted from 7 October through 20 November 2004, sent a two-page open questionnaire to a variety of hospital executive personnel - medical directors, chief administrators, medical school deans, and public information officers - to determine their views on this subject. The response rate was 34%. Without contesting either the legitimacy of the expectation for information or the transparency owed to patients, health professionals expressed the need to know in advance the "rules of the game" and the methodology of the rating techniques to be used. Most reported few changes in their professional behavior due to these publications, the methodology and criteria of which they contested. They suggested changes including different criteria and indicators for the rating, the ability to contest the conclusions drawn from the PMSI data, and the need for preliminary work to define criteria by working groups composed of physicians, other professionals, and even those outside the health field. On the other hand, only half were willing to participate in such a working group. These hospital managers see a need for specialists in the analysis of hospital data, who can clarify the meaning of the statistics and improve the public's understanding of them, now shaped by the mass media's failure to provide meaningful analysis.

Methods to systematically review and meta-analyse observational studies: a systematic scoping review of recommendations.

PubMed

Mueller, Monika; D'Addario, Maddalena; Egger, Matthias; Cevallos, Myriam; Dekkers, Olaf; Mugglin, Catrina; Scott, Pippa

2018-05-21

Systematic reviews and meta-analyses of observational studies are frequently performed, but no widely accepted guidance is available at present. We performed a systematic scoping review of published methodological recommendations on how to systematically review and meta-analyse observational studies. We searched online databases and websites and contacted experts in the field to locate potentially eligible articles. We included articles that provided any type of recommendation on how to conduct systematic reviews and meta-analyses of observational studies. We extracted and summarised recommendations on pre-defined key items: protocol development, research question, search strategy, study eligibility, data extraction, dealing with different study designs, risk of bias assessment, publication bias, heterogeneity, statistical analysis. We summarised recommendations by key item, identifying areas of agreement and disagreement as well as areas where recommendations were missing or scarce. The searches identified 2461 articles of which 93 were eligible. Many recommendations for reviews and meta-analyses of observational studies were transferred from guidance developed for reviews and meta-analyses of RCTs. Although there was substantial agreement in some methodological areas there was also considerable disagreement on how evidence synthesis of observational studies should be conducted. Conflicting recommendations were seen on topics such as the inclusion of different study designs in systematic reviews and meta-analyses, the use of quality scales to assess the risk of bias, and the choice of model (e.g. fixed vs. random effects) for meta-analysis. There is a need for sound methodological guidance on how to conduct systematic reviews and meta-analyses of observational studies, which critically considers areas in which there are conflicting recommendations.

From bed to bench: bridging from informatics practice to theory: an exploratory analysis.

PubMed

Haux, R; Lehmann, C U

2014-01-01

In 2009, Applied Clinical Informatics (ACI)--focused on applications in clinical informatics--was launched as a companion journal to Methods of Information in Medicine (MIM). Both journals are official journals of the International Medical Informatics Association. To explore which congruencies and interdependencies exist in publications from theory to practice and from practice to theory and to determine existing gaps. Major topics discussed in ACI and MIM were analyzed. We explored if the intention of publishing companion journals to provide an information bridge from informatics theory to informatics practice and vice versa could be supported by this model. In this manuscript we will report on congruencies and interdependences from practice to theory and on major topics in MIM. Retrospective, prolective observational study on recent publications of ACI and MIM. All publications of the years 2012 and 2013 were indexed and analyzed. Hundred and ninety-six publications were analyzed (ACI 87, MIM 109). In MIM publications, modelling aspects as well as methodological and evaluation approaches for the analysis of data, information, and knowledge in biomedicine and health care were frequently raised - and often discussed from an interdisciplinary point of view. Important themes were ambient-assisted living, anatomic spatial relations, biomedical informatics as scientific discipline, boosting, coding, computerized physician order entry, data analysis, grid and cloud computing, health care systems and services, health-enabling technologies, health information search, health information systems, imaging, knowledge-based decision support, patient records, signal analysis, and web science. Congruencies between journals could be found in themes, but with a different focus on content. Interdependencies from practice to theory, found in these publications, were only limited. Bridging from informatics theory to practice and vice versa remains a major component of successful research and practice as well as a major challenge.

Update On The Development, Testing, And Manufacture Of High Density LEU-Foil Targets For The Production Of Mo-99

DOE Office of Scientific and Technical Information (OSTI.GOV)

Creasy, John T

2015-05-12

This project has the objective to reduce and/or eliminate the use of HEU in commerce. Steps in the process include developing a target testing methodology that is bounding for all Mo-99 target irradiators, establishing a maximum target LEU-foil mass, developing a LEU-foil target qualification document, developing a bounding target failure analysis methodology (failure in reactor containment), optimizing safety vs. economics (goal is to manufacture a safe, but relatively inexpensive target to offset the inherent economic disadvantage of using LEU in place of HEU), and developing target material specifications and manufacturing QC test criteria. The slide presentation is organized under themore » following topics: Objective, Process Overview, Background, Team Structure, Key Achievements, Experiment and Activity Descriptions, and Conclusions. The High Density Target project has demonstrated: approx. 50 targets irradiated through domestic and international partners; proof of concept for two front end processing methods; fabrication of uranium foils for target manufacture; quality control procedures and steps for manufacture; multiple target assembly techniques; multiple target disassembly devices; welding of targets; thermal, hydraulic, and mechanical modeling; robust target assembly parametric studies; and target qualification analysis for insertion into very high flux environment. The High Density Target project has tested and proven several technologies that will benefit current and future Mo-99 producers.« less

[Occupational epidemiology: from analysis of the apparent to investigation of the unknown].

PubMed

Zocchetti, C; Pesatori, Angela; Consonni, D

2003-01-01

This paper, as a contribution for the centenary celebration of the establishment of the "Clinica del Lavoro Luigi Devoto" in Milan (Italy), presents a brief 30 year history of the activities of its Department of Occupational Epidemiology. Studies and methodological contributions that characterized the first decade of activity are presented and grouped under the heading of analysis of known health effects. The second decade was dominated by the studies and activities that originated from the Seveso accident (dioxin), with an initial interest towards molecular epidemiology, which became increasingly relevant during the third decade when we addressed topics like melanoma, lung cancer, and benzene, in addition to dioxin. More traditional occupational approaches were not dismissed and cohort mortality studies are currently under way (textile dyeing and finishing industry, sulfuric acid, tetrafluoroethylene). Pros and cons of the epidemiologic approach are discussed in the context of occupational health and the strength of its methodological apparatus is suggested as a fundamental tool for studying adverse occupational health effects. In contrast, it is stressed how occupational epidemiology has been poorly used in the application of law 626/94. Considering that contemporary epidemiology is much more inclined towards the discovery of new work-related risks (electromagnetic fields, air pollution) than the description of known health effects, the paper suggests that occupational epidemiology enlarge its interests: people and environment outside the factories might be good candidates for study.

Nutrition Education for Pediatric Gastroenterology, Hepatology and Nutrition Fellows: A Survey of NASPGHAN Fellowship Training Programs

PubMed Central

Martinez, J. Andres; Koyama, Tatsuki; Acra, Sari; Mascarenhas, Maria R.; Shulman, Robert J.

2012-01-01

Objectives The aim of the study was to assess the methodology and content of nutrition education during gastroenterology fellowship training and the variability among the different programs. Methods A survey questionnaire was completed by 43 fellowship training directors of 62 active programs affiliated to NASPGHAN, including sites in the United States, Canada and Mexico. The data were examined for patterns in teaching methodology and coverage of specific nutrition topics based on Level 1 training in nutrition, which is the minimum requirement according to published NASPGHAN fellowship training guidelines. Results The majority of the teaching was conducted by MD degree faculty (61%), and most of the education was provided through clinical care experiences. Only 31% of Level 1 nutrition topics were consistently covered by more than 80% of programs, and coverage did not correlate with the size of the programs. Competency in nutrition training was primarily assessed through questions to individuals or groups of fellows (77 and 65%, respectively). Program directors cited a lack of faculty interested in nutrition and a high workload as common obstacles for teaching. Conclusions The methodology of nutrition education during gastroenterology fellowship training is for the most part unstructured and inconsistent among the different programs. The minimum Level 1 requirements are not consistently covered. The development of core curriculums and learning modules may be beneficial in improving nutrition education. PMID:22343911

Current Grid Generation Strategies and Future Requirements in Hypersonic Vehicle Design, Analysis and Testing

NASA Technical Reports Server (NTRS)

Papadopoulos, Periklis; Venkatapathy, Ethiraj; Prabhu, Dinesh; Loomis, Mark P.; Olynick, Dave; Arnold, James O. (Technical Monitor)

1998-01-01

Recent advances in computational power enable computational fluid dynamic modeling of increasingly complex configurations. A review of grid generation methodologies implemented in support of the computational work performed for the X-38 and X-33 are presented. In strategizing topological constructs and blocking structures factors considered are the geometric configuration, optimal grid size, numerical algorithms, accuracy requirements, physics of the problem at hand, computational expense, and the available computer hardware. Also addressed are grid refinement strategies, the effects of wall spacing, and convergence. The significance of grid is demonstrated through a comparison of computational and experimental results of the aeroheating environment experienced by the X-38 vehicle. Special topics on grid generation strategies are also addressed to model control surface deflections, and material mapping.

[Edith Magalhães Fraenkel: the greatest figure of Brazilian nursing].

PubMed

Oguisso, Taka; Freitas, Genival Fernandes de; Takashi, Magali Hiromi

2013-10-01

The present study aimed to describe and analyze the career of Edith Magalhães Fraenkel and her important legacy to Brazilian nursing. The methodology chosen was a documentary analysis of her areas of participation based on documents of the Historical Cultural Center of Iberian-American School of Nursing of the University of São Paulo (Universidade de São Paulo, USP) and in the Rectory of the same University. The following thematic topics were categorized: preparation for leadership, moving to São Paulo, creation of the School of Nursing of USP, event organization, and unique developments at the end of her career. We conclude that Mrs. Edith Fraenkel is the most important figure of Brazilian nursing, thanks to her immeasurable work as a leader of the profession, nationally and internationally.

Design and ergonomics. Methods for integrating ergonomics at hand tool design stage.

PubMed

Marsot, Jacques; Claudon, Laurent

2004-01-01

As a marked increase in the number of musculoskeletal disorders was noted in many industrialized countries and more specifically in companies that require the use of hand tools, the French National Research and Safety Institute (INRS) launched in 1999 a research project on the topic of integrating ergonomics into hand tool design, and more particularly to a design of a boning knife. After a brief recall of the difficulties of integrating ergonomics at the design stage, the present paper shows how 3 design methodological tools--Functional Analysis, Quality Function Deployment and TRIZ--have been applied to the design of a boning knife. Implementation of these tools enabled us to demonstrate the extent to which they are capable of responding to the difficulties of integrating ergonomics into product design.

Dynamics of global supply chain and electric power networks: Models, pricing analysis, and computations

NASA Astrophysics Data System (ADS)

Matsypura, Dmytro

In this dissertation, I develop a new theoretical framework for the modeling, pricing analysis, and computation of solutions to electric power supply chains with power generators, suppliers, transmission service providers, and the inclusion of consumer demands. In particular, I advocate the application of finite-dimensional variational inequality theory, projected dynamical systems theory, game theory, network theory, and other tools that have been recently proposed for the modeling and analysis of supply chain networks (cf. Nagurney (2006)) to electric power markets. This dissertation contributes to the extant literature on the modeling, analysis, and solution of supply chain networks, including global supply chains, in general, and electric power supply chains, in particular, in the following ways. It develops a theoretical framework for modeling, pricing analysis, and computation of electric power flows/transactions in electric power systems using the rationale for supply chain analysis. The models developed include both static and dynamic ones. The dissertation also adds a new dimension to the methodology of the theory of projected dynamical systems by proving that, irrespective of the speeds of adjustment, the equilibrium of the system remains the same. Finally, I include alternative fuel suppliers, along with their behavior into the supply chain modeling and analysis framework. This dissertation has strong practical implications. In an era in which technology and globalization, coupled with increasing risk and uncertainty, complicate electricity demand and supply within and between nations, the successful management of electric power systems and pricing become increasingly pressing topics with relevance not only for economic prosperity but also national security. This dissertation addresses such related topics by providing models, pricing tools, and algorithms for decentralized electric power supply chains. This dissertation is based heavily on the following coauthored papers: Nagurney, Cruz, and Matsypura (2003), Nagurney and Matsypura (2004, 2005, 2006), Matsypura and Nagurney (2005), Matsypura, Nagurney, and Liu (2006).

Current challenges in bioequivalence, quality, and novel assessment technologies for topical products.

PubMed

Yacobi, Avraham; Shah, Vinod P; Bashaw, Edward D; Benfeldt, Eva; Davit, Barbara; Ganes, Derek; Ghosh, Tapash; Kanfer, Isadore; Kasting, Gerald B; Katz, Lindsey; Lionberger, Robert; Lu, Guang Wei; Maibach, Howard I; Pershing, Lynn K; Rackley, Russell J; Raw, Andre; Shukla, Chinmay G; Thakker, Kailas; Wagner, Nathalie; Zovko, Elizabeta; Lane, Majella E

2014-04-01

This paper summarises the proceedings of a recent workshop which brought together pharmaceutical scientists and dermatologists from academia, industry and regulatory agencies to discuss current regulatory issues and industry practices for establishing therapeutic bioequivalence (BE) of dermatologic topical products. The methods currently available for assessment of BE were reviewed as well as alternatives and the advantages and disadvantages of each method were considered. Guidance on quality and performance of topical products was reviewed and a framework to categorise existing and alternative methods for evaluation of BE was discussed. The outcome of the workshop emphasized both a need for greater attention to quality, possibly, via a Quality-By-Design (QBD) approach and a need to develop a "whole toolkit" approach towards the problem of determination of rate and extent in the assessment of topical bioavailability. The discussion on the BE and clinical equivalence of topical products revealed considerable concerns about the variability present in the current methodologies utilized by the industry and regulatory agencies. It was proposed that academicians, researchers, the pharmaceutical industry and regulators work together to evaluate and validate alternative methods that are based on both the underlying science and are adapted to the drug product itself instead of single "universal" method.

Digital Methodology to implement the ECOUTER engagement process.

PubMed

Wilson, Rebecca C; Butters, Oliver W; Clark, Tom; Minion, Joel; Turner, Andrew; Murtagh, Madeleine J

2016-01-01

ECOUTER ( E mploying CO ncept u al schema for policy and T ranslation E  in R esearch - French for 'to listen' - is a new stakeholder engagement method incorporating existing evidence to help participants draw upon their own knowledge of cognate issues and interact on a topic of shared concern. The results of an ECOUTER can form the basis of recommendations for research, governance, practice and/or policy. This paper describes the development of a digital methodology for the ECOUTER engagement process based on currently available mind mapping freeware software. The implementation of an ECOUTER process tailored to applications within health studies are outlined for both online and face-to-face scenarios. Limitations of the present digital methodology are discussed, highlighting the requirement of a purpose built software for ECOUTER research purposes.

The Best Children's Museums--According to "Child" Magazine.

ERIC Educational Resources Information Center

West, Robert Mac

2002-01-01

Reports the first known survey to evaluate and rank children's museums. The survey was conducted by Child magazine but questions the methodology used to derive the rankings. Identifies the top 50 museums in the rankings. Notes that dinosaurs remain a popular topic and many new programs are designed for very young children. (DLH)

Craft Training in Russia: Theory and Practice of Development

ERIC Educational Resources Information Center

Romantsev, Gennadij M.; Efanov, Andrei V.; Moiseev, Andrei V.; Bychkova, Ekaterina Yu.; Karpova, Natalia P.; Tidemann, Bruno

2016-01-01

The relevance of the research topic is substantiated by the social commitment to the establishment of a system of craft training focused on training personnel for craft enterprises. The purpose of the article is to provide theoretical and methodological substantiation of the necessity to provide organizational and pedagogical foundations for the…

Systematic Reviews of Research in Education: Aims, Myths and Multiple Methods

ERIC Educational Resources Information Center

Gough, David; Thomas, James

2016-01-01

Systematic reviews are still a controversial topic in some quarters, with the arguments for and against their use being well-rehearsed. In an attempt to advance a more nuanced approach to thinking about systematic reviewing, this paper illustrates the wide range of theoretical perspectives, methodologies and purposes that underpin the vast range…

Higher Education: Handbook of Theory and Research. Volume II.

ERIC Educational Resources Information Center

Smart, John C., Ed.

Theory and research on the effectiveness of college operations are covered in 12 chapters. Current research on each topic is reviewed, with attention to conceptual and methodological issues, and an agenda for future research is offered. Chapter titles and authors are as follows: "Transformational Leadership in Colleges and Universities" (Kim S.…

Some aspects of inventory integration

Treesearch

Jerry Leech

2000-01-01

Integrating such disparate topics as are covered by this conference is daunting, because to do it well requires in-depth expertise of many complex technical methodologies. Based on experiences in Asia and Australia, it is suggested that there can never be one inventory design or one planning system, it will increasingly be necessary to implement specialized inventories...

76 FR 32971 - Proposed Priority for the Disability and Rehabilitation Research Projects and Centers Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-07

... and systematic search of the research literature on a topic for relevant studies, which are then evaluated using pre-determined, objective criteria for relevance and methodological rigor. In a systematic review, the evidence from relevant studies that meet the pre-determined criteria is then analyzed and...

Epistemic Cognition when Students Read Multiple Documents Containing Conflicting Scientific Evidence: A Think-Aloud Study

ERIC Educational Resources Information Center

Ferguson, Leila E.; Braten, Ivar; Stromso, Helge I.

2012-01-01

This study used think-aloud methodology to investigate 51 Norwegian undergraduates' topic-specific epistemic cognition while working with six documents presenting conflicting views on the issue of cell phones and potential health risks. Results showed that students' epistemic cognition was represented by one dimension concerning the certainty and…

The Philosopher, the Rabbi, and the Rhetorician

ERIC Educational Resources Information Center

Handelman, Susan

2010-01-01

The author explores the topic of Jewish rhetorics by examining how particular Jewish thinkers have conceptualized the ethical relation between self and other. She draws particular attention to the tacit rhetorical methodology at work in the teachings of Rabbi Yehouda Leon Askenazi. She shows that he distinguished himself from the more well-known…

Educational Technology Research Journals: "Journal of Educational Computing Research," 2003-2012

ERIC Educational Resources Information Center

Nyland, Rob; Anderson, Noelle; Beckstrom, Tyler; Boren, Michael; Thomas, Rebecca; West, Richard E.

2015-01-01

This article analyzes articles published in the "Journal of Educational Computing Research" ("JECR") from 2003 to 2012. The authors analyzed the articles looking for trends in article types and methodologies, the most common topics addressed in the articles, the top-cited articles, and the top authors during the period. The…

Colleges and Universities Want to Be Your Friend: Communicating via Online Social Networking

ERIC Educational Resources Information Center

Wandel, Tamara L.

2008-01-01

This article presents a compilation of data regarding the role of online social networks within campus communities, specifically for nonacademic purposes. Both qualitative and quantitative data methodologies are used to provide a unique perspective on a constantly evolving topic. Interviews of students and administrators allow for candid…

Contributions of Piagetian and Post-Piagetian Theories to Education

ERIC Educational Resources Information Center

Marchand, Helena

2012-01-01

The aim of this article was to reflect on the contributions of Piagetian and neo-Piagetian theories to education. Topics analyzed included the evolution of Piaget's and co-workers' theory, the reaction by the scientific community to the main theoretical and methodological aspects of each period of his work, the educational potentialities of…

Applying the Collective Causal Mapping Methodology to Operations Management Curriculum Development

ERIC Educational Resources Information Center

Hays, Julie M.; Bouzdine-Chameeva, Tatiana; Goldstein, Susan Meyer; Hill, Arthur V.; Scavarda, Annibal José

2007-01-01

Although the field of operations management has come a long way since its beginnings in scientific management, the field still appears somewhat amorphous and unstructured to many. Introductory operations management textbooks usually include a number of largely disjointed topics, which leave many students (and their instructors) without a coherent…

Creating a Sustainable University and Community through a Common Experience

ERIC Educational Resources Information Center

Lopez, Omar S.

2013-01-01

Purpose: This article aims to provide an overview of Texas State University's Common Experience, an innovative initiative that engaged tens of thousands of people in shared consideration of sustainability as a single topic during academic year 2010-2011. Design/methodology/approach: The discourse begins with an overview of the Common Experience…

Permeability between VET and Higher Education--A Way of Human Resource Development

ERIC Educational Resources Information Center

Spottl, Georg

2013-01-01

Purpose: Parity of esteem between general and vocational education is a widely discussed topic in those countries which have established a system of vocational education and training (VET) beside the system of general education, leading to numerous qualifications and licenses. This paper aims to address this issue. Design/methodology/approach: An…

Inclusive Education Policy: What the Leadership of Canadian Teacher Associations Has to Say about It

ERIC Educational Resources Information Center

Thompson, S. Anthony; Lyons, Wanda; Timmons, Vianne

2015-01-01

In inclusive education research, rarely are teacher associations a topic of investigation despite their critical role in its implementation and efficacy. A study was conducted as part of the Canadian Disability Policy Alliance using a "learning collaborative" methodology that explored the extent to which Canadian provincial/territorial…

Documentation for the 2003-04 Schools and Staffing Survey. NCES 2007-337

ERIC Educational Resources Information Center

Tourkin, Steven C.; Warner, Toni; Parmer, Randall; Cole, Cornette; Jackson, Betty; Zukerberg, Andrew; Cox, Shawna; Soderberg, Andrew

2007-01-01

This report serves as the survey documentation for the design and implementation of the 2003-04 Schools and Staffing Survey. Topics covered include the sample design, survey methodology, data collection procedures, data processing, response rates, imputation procedures, weighting and variance estimation, review of the quality of data, the types of…

Examination of Capital Murder Jurors' Deliberations: Methods and Issues

ERIC Educational Resources Information Center

Price, Keith; Coleman, Susan; Byrd, Gary R.

2014-01-01

The study of capital juries remains a subject of critical interest for the public and for legislative and judicial policy makers as well as legal scholars and social scientists. Cowan, Thompson, and Ellsworth established one of the standard methodologies for examination of this topic in their 1984 seminal study by observing the subjects' debate…

Linearization: Students Forget the Operating Point

ERIC Educational Resources Information Center

Roubal, J.; Husek, P.; Stecha, J.

2010-01-01

Linearization is a standard part of modeling and control design theory for a class of nonlinear dynamical systems taught in basic undergraduate courses. Although linearization is a straight-line methodology, it is not applied correctly by many students since they often forget to keep the operating point in mind. This paper explains the topic and…

An Assessment of Illinois Area Vocational Centers, 1976.

ERIC Educational Resources Information Center

Hamilton, James A. G.

This 1976 study presents an update of a 1971 assessment of Illinois Area Vocational Centers (AVCs). The following topics are discussed in sections of this report: (1) methodology of the study which included meetings with an advisory committee of AVC directors, interviews at each of twenty-nine operating AVCs, distribution of 2,000 of eleven…

Causes and Consequences of Early Life Health. NBER Working Paper No. 15637

ERIC Educational Resources Information Center

Case, Anne; Paxson, Christina

2010-01-01

We examine the consequences of childhood health for economic and health outcomes in adulthood, using height as a marker of health in childhood. After reviewing previous evidence, we present a conceptual framework that highlights data limitations and methodological problems associated with the study of this topic. We present estimates of the…

The Nature of Psychology: Reflections on University Teachers' Experiences of Teaching Sensitive Topics

ERIC Educational Resources Information Center

Hulme, Julie A.; Kitching, Helen J.

2017-01-01

This paper describes one aspect of a larger scale qualitative study conducted to investigate psychology-specific issues in learning and teaching in higher education. Participants included academic psychologists from across the career spectrum and from diverse UK universities. A semi-structured focus group methodology was employed, and results were…

Team-Teaching a Current Events-Based Biology Course for Nonmajors

ERIC Educational Resources Information Center

Bondos, Sarah E.; Phillips, Dereth

2008-01-01

Rice University has created a team-taught interactive biology course for nonmajors with a focus on cutting edge biology in the news--advances in biotechnology, medicine, and science policy, along with the biological principles and methodology upon which these advances are based. The challenges inherent to teaching current topics were minimized by…

Systematic Instruction of Functional Skills for Students and Adults with Disabilities

ERIC Educational Resources Information Center

Storey, Keith; Miner, Craig

2011-01-01

This text is a clear and current description of the instructional strategies that can be immediately applied across age groups and disability labels. An evidence-based instructional methodology is provided, which has proved to be effective in teaching skills to students and adults with disabilities. Signature topics include: (1) a…

Virtual Communities in Europe: The European Library Approach

ERIC Educational Resources Information Center

Stigter, Fleur

2009-01-01

Purpose: The purpose of this paper is to provide an overview of The Bridging Worlds Conference which was held in October 2008 in Singapore. Design/methodology/approach: One of the main topics the National Library Board of Singapore, the organising party, wished to address was the roles cultural institutions, such as libraries, may play in…

The LACIE data bases: Design considerations

NASA Technical Reports Server (NTRS)

Westberry, L. E. (Principal Investigator)

1979-01-01

The implementation of direct access storage devices for LACIE is discussed with emphasis on the storage and retrieval of image data. Topics covered include the definition of the problem, the solution methodology (design decisions), the initial operational structure, and the modifications which were incorporated. Some conclusions and projections of future problems to be solved are also presented.

Constructing Core Journal Lists: Mixing Science and Alchemy.

ERIC Educational Resources Information Center

Corby, Katherine

2003-01-01

Via an overview of core journal studies, emphasizing the social sciences and education, this review looks for best practices in both motivation and methodology. Selection decisions receive particular focus. Lack of correlation between methods is indicative of the complexity of the topic and the need for judgment in design and use. (Author)

A Binary Programming Approach to Automated Test Assembly for Cognitive Diagnosis Models

ERIC Educational Resources Information Center

Finkelman, Matthew D.; Kim, Wonsuk; Roussos, Louis; Verschoor, Angela

2010-01-01

Automated test assembly (ATA) has been an area of prolific psychometric research. Although ATA methodology is well developed for unidimensional models, its application alongside cognitive diagnosis models (CDMs) is a burgeoning topic. Two suggested procedures for combining ATA and CDMs are to maximize the cognitive diagnostic index and to use a…

The Journey of Organizational Unlearning: A Conversation with William H. Starbuck

ERIC Educational Resources Information Center

Nguyen, Nhien

2017-01-01

Purpose: This paper aims to provide an overview of the concept "organizational unlearning" and its development since it was first introduced to the management literature and presents a useful perspective that can help to advance the conceptual development of this topic. Design/methodology/approach: Through a conversation with celebrated…

Technology-Supported Learning in Secondary and Undergraduate Biological Education: Observations from Literature Review

ERIC Educational Resources Information Center

Lee, Silvia Wen-Yu; Tsai, Chin-Chung

2013-01-01

We conducted a literature review of using educational technology in biology learning from 2001 to 2010. A total of 36 empirical articles were included for review. Based upon the content analyses of these studies, such as technologies utilized, student sample, biological topics involved, the research purpose, and methodology, the following…

Stakeholders Perceptions of a Universal Sustainability Assessment in Higher Education--A Review of Empirical Evidence

ERIC Educational Resources Information Center

Maragakis, Antonios; van den Dobbelsteen, Andy; Maragakis, Alexandros

2016-01-01

The progress of sustainability within higher education has steadily increased in focus over the last decade and has increasingly become a topic of academic research. As institutions investigate, implement and market sustainability efforts, there is a myriad of sustainability assessment methodologies currently available. This assortment of…

The Service Learning Projects: Stakeholder Benefits and Potential Class Topics

ERIC Educational Resources Information Center

Rutti, Raina M.; LaBonte, Joanne; Helms, Marilyn Michelle; Hervani, Aref Agahei; Sarkarat, Sy

2016-01-01

Purpose: The purpose of this paper is to summarize the benefits of including a service learning project in college classes and focusses on benefits to all stakeholders, including students, community, and faculty. Design/methodology/approach: Using a snowball approach in academic databases as well as a nominal group technique to poll faculty, key…

How to Arrive at Good Research Questions?

ERIC Educational Resources Information Center

Gafoor, K. Abdul

2008-01-01

Identifying an area of research a topic, deciding on a problem, and formulating it in to a researchable question are very difficult stages in the whole research process at least for beginners. Few books on research methodology elaborates the various process involved in problem selection and clarification. Viewing research and problem selection as…

Taking a Systems View of Creativity: On the Right Path toward Understanding

ERIC Educational Resources Information Center

Hennessey, Beth A.

2017-01-01

In our 2010 "Annual Review" paper, Teresa Amabile and I argued that a virtual explosion of topics, viewpoints, and methodologies had muddied the investigative waters. Few, if any, "big" questions were being pursued by a critical mass of creativity researchers. Instead, investigators in one subfield seemed entirely unaware of…

AAHPER Research Consortium Symposium Papers: Socio-Psychological Dimensions, Research Design and Safety. Volume II, Book 3.

ERIC Educational Resources Information Center

Cox, Richard H., Ed.

This collection focuses on research topics in physical education and athletics and includes the following papers: Methodological Problems in the Assessment of Personality from the Psychoanalytic, Behavioral and Cognitive Positions; Some Factors Affecting the Performance of Women in Sports and Activity; Multivariate Considerations in Children's…

Elaborer un exercice de grammaire (Working Out a Grammar Exercise)

ERIC Educational Resources Information Center

Principaud, Jeanne-Marie

1977-01-01

An elaboration of the official instruction on teaching French to native speakers in elementary school. The topics covered are: Methodological development of exercises; the linguistic ability and milieu of the students; operative criteria; and the question of a logical progression or spontaneous use of grammar exercises. (Text is in French.) (AMH)

What Are Drivers for Informal Learning?

ERIC Educational Resources Information Center

Schürmann, Eva; Beausaert, Simon

2016-01-01

Purpose: The topic of informal learning at work has received increasing attention in the past years. The purpose of this study is to explore in which informal learning activities employees engage and what are the drivers for informal learning. Design/Methodology/Approach: Semi-structured interviews were taken from ten human resources (HR) and ten…

The Discursive Management of Emotionality in the L2 Research Interview

ERIC Educational Resources Information Center

Prior, Matthew T.

2011-01-01

This study investigates the ways in which emotions and emotionality are managed as topics and resources in second language (L2) research interviews. A continued challenge for researchers is how to define and operationalize emotions and other putative psychological phenomena. One popular research methodology that treats emotions as the object and…

Proceedings of the European Conference on Research in Rehabilitation (Second, Duesseldorf, West Germany, November 18-19, 1985).

ERIC Educational Resources Information Center

Roth, Helga, Ed.

1987-01-01

These conference proceedings deal with an interdisciplinary approach to reducing handicapping conditions and ensuring integration of and equal participation by people with disabilities in all aspects of community life. Papers from plenary sessions cover such topics as psychological and social aspects of rehabilitation, research methodology in…

Situating Standard Setting within Argument-Based Validity

ERIC Educational Resources Information Center

Papageorgiou, Spiros; Tannenbaum, Richard J.

2016-01-01

Although there has been substantial work on argument-based approaches to validation as well as standard-setting methodologies, it might not always be clear how standard setting fits into argument-based validity. The purpose of this article is to address this lack in the literature, with a specific focus on topics related to argument-based…

Critical Studies on the Ideological Structure of Personality.

ERIC Educational Resources Information Center

Barratt, Barnaby B.; And Others

This document contains four papers about the ideological structure of personality. A proposal for a theoretical and methodological reworking of the life-historical inquiry of personality psychology is presented along with a report of some preliminary studies that employ an intensive life-history approach to a distinct topic within the context of…

Repatriation of Expatriate Employees, Knowledge Transfer, and Organizational Learning: What Do We Know?

ERIC Educational Resources Information Center

Nery-Kjerfve, Tania; McLean, Gary N.

2012-01-01

Purpose: The purpose of this paper is to present a review of the topic of repatriation and the potential benefits of the use of repatriated employees to enhance global knowledge and organizational learning in multinational corporations. Design/methodology/approach: The paper provides an integrative literature review of articles published on…

Tretinoin peel: a critical view*

PubMed Central

Sumita, Juliana Mayumi; Leonardi, Gislaine Ricci; Bagatin, Ediléia

2017-01-01

The tretinoin peel, also known as retinoic acid peel, is a superficial peeling often performed in dermatological clinics in Brazil. The first study on this was published in 2001, by Cuce et al., as a treatment option for melasma. Since then, other studies have reported its applicability with reasonable methodology, although without a consistent scientific background and consensus. Topical tretinoin is used for the treatment of various dermatoses such as acne, melasma, scars, skin aging and non-melanoma skin cancer. The identification of retinoids cellular receptors was reported in 1987, but a direct cause-effect relation has not been established. This article reviews studies evaluating the use of topical tretinoin as agent for superficial chemical peel. Most of them have shown benefits in the treatment of melasma and skin aging. A better quality methodology in the study design, considering indication and intervention is indispensable regarding concentration, vehicle and treatment regimen (interval and number of applications). Additionally, more controlled and randomized studies comparing the treatment with tretinoin cream versus its use as a peeling agent, mainly for melasma and photoaging, are necessary. PMID:29186249

Tretinoin peel: a critical view.

PubMed

Sumita, Juliana Mayumi; Leonardi, Gislaine Ricci; Bagatin, Ediléia

2017-01-01

The tretinoin peel, also known as retinoic acid peel, is a superficial peeling often performed in dermatological clinics in Brazil. The first study on this was published in 2001, by Cuce et al., as a treatment option for melasma. Since then, other studies have reported its applicability with reasonable methodology, although without a consistent scientific background and consensus. Topical tretinoin is used for the treatment of various dermatoses such as acne, melasma, scars, skin aging and non-melanoma skin cancer. The identification of retinoids cellular receptors was reported in 1987, but a direct cause-effect relation has not been established. This article reviews studies evaluating the use of topical tretinoin as agent for superficial chemical peel. Most of them have shown benefits in the treatment of melasma and skin aging. A better quality methodology in the study design, considering indication and intervention is indispensable regarding concentration, vehicle and treatment regimen (interval and number of applications). Additionally, more controlled and randomized studies comparing the treatment with tretinoin cream versus its use as a peeling agent, mainly for melasma and photoaging, are necessary.

The Histochemistry and Cell Biology omnium-gatherum: the year 2015 in review.

PubMed

Taatjes, Douglas J; Roth, Jürgen

2016-03-01

We provide here our annual review/synopsis of all of the articles published in Histochemistry and Cell Biology (HCB) for the preceding year. In 2015, HCB published 102 articles, representing a wide variety of topics and methodologies. For ease of access to these differing topics, we have created categories, as determined by the types of articles presented to provide a quick index representing the general areas covered. This year, these categories include: (1) advances in methodologies; (2) molecules in health and disease; (3) organelles, subcellular structures, and compartments; (4) the nucleus; (5) stem cells and tissue engineering; (6) cell cultures: properties and capabilities; (7) connective tissues and extracellular matrix; (8) developmental biology; (9) nervous system; (10) musculoskeletal system; (11) respiratory and cardiovascular system; (12) liver and gastrointestinal tract; and (13) male and female reproductive systems. Of note, the categories proceed from methods development, to molecules, intracellular compartments, stem cells and cell culture, extracellular matrix, developmental biology, and finishing with various organ systems, hopefully presenting a logical journey from methods to organismal molecules, cells, and whole tissue systems.