Family Communication Patterns, Rebelliousness, and Adolescent Reactions to Anti-drug PSAs.

ERIC Educational Resources Information Center

Skinner, Ellen R.; Slater, Michael D.

1995-01-01

Proposes that the impact of adolescents' reactions to antidrug messages is contingent upon the extent of adolescent rebelliousness. Studied 51 adolescents who saw 6 antidrug Public Service Advertisements (PSAs). Rebellious adolescents from the more authoritarian, conformity-oriented families who were shown antidrug PSAs considered the messages…

Children's Perceptions of TV Commercials and Products: The Effects of PSAs.

ERIC Educational Resources Information Center

Christenson, Peter Gilbert

1982-01-01

Investigated whether public service announcements (PSAs) on the nature of television advertising affect (1) children's awareness of advertising intent; (2) their belief in its truthfulness; and (3) their perception of advertised products. Data indicate that PSAs can influence children's perceptions of advertising's credibility and can affect their…

Where is the evidence supporting public service announcements to eliminate mental illness stigma?

PubMed

Corrigan, Patrick W

2012-01-01

Advocates and social marketers have used substantial resources to develop public service announcements (PSAs) as a lead strategy in public education and awareness campaigns meant to eliminate stigma associated with mental illness. Evaluations of PSAs are needed to determine whether this is a good investment. The author notes that very few studies have been reported in the peer-reviewed medical and psychological research literature addressing this question. Reports of government contractors suggest that PSAs have some effect as measured by population penetration, but such data provide no meaningful evidence about the impact of PSAs, such as real-world change in prejudicial attitudes and discriminatory behaviors. The author considers reasons for the limited impact of PSAs and proposes that social marketing campaigns could enhance their impact by targeting local groups.

47 CFR 73.674 - Digital television transition notices by broadcasters.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PSAs and crawls with antenna notices. (7) Rescanning notices—Beginning April 1, 2009, all stations must...) of this section may replace up to 25 percent of their daily PSAs and crawls with rescanning notices... PSAs and crawls with help center notices. (c) Consumer Education Campaign Option One: (1) From March 27...

A Psychophysiological Study of Processing HIV/AIDS Public Service Announcements: The Effects of Novelty Appeals, Sexual Appeals, Narrative Versus Statistical Evidence, and Viewer's Sex.

PubMed

Zhang, Jueman Mandy; Chen, Gina Masullo; Chock, T Makana; Wang, Yi; Ni, Liqiang; Schweisberger, Valarie

2016-07-01

This study used self-reports and physiological measures-heart rate (HR) and skin conductance level (SCL)-to examine the effects of novelty appeals, sexual appeals, narrative versus statistical evidence, and viewer's sex on cognitive and emotional processing of HIV/AIDS public service announcements (PSAs) among heterosexually active single college students. Novelty or sexual appeals differently affected self-reported attention and cognitive effort as measured by HR. High- rather than low-novelty HIV/AIDS PSAs, perceived as more attention-eliciting, did not lead to more cognitive effort. High- rather than low-sex HIV/AIDS PSAs, not perceived as more attention-eliciting, led to more cognitive effort as reflected by greater HR deceleration. Novelty or sexual appeals also affected self-reported emotional arousal and SCL differently. HIV/AIDS PSAs with high rather than low levels of novelty or sexual appeals led to greater self-reported arousal, but not greater SCL. Message evidence interacted with message appeals to affect cognitive effort. Participants exerted greater cognitive effort during high- rather than low-novelty narrative HIV/AIDS PSAs, and during low- rather than high-novelty statistical ones. The advantage of high over low sexual appeals was more obvious in statistical than in narrative HIV/AIDS PSAs. Males reported greater emotional arousal than females during high- rather than low-sex HIV/AIDS PSAs.

Parallel Climate Data Assimilation PSAS Package

NASA Technical Reports Server (NTRS)

Ding, Hong Q.; Chan, Clara; Gennery, Donald B.; Ferraro, Robert D.

1996-01-01

We have designed and implemented a set of highly efficient and highly scalable algorithms for an unstructured computational package, the PSAS data assimilation package, as demonstrated by detailed performance analysis of systematic runs on up to 512node Intel Paragon. The equation solver achieves a sustained 18 Gflops performance. As the results, we achieved an unprecedented 100-fold solution time reduction on the Intel Paragon parallel platform over the Cray C90. This not only meets and exceeds the DAO time requirements, but also significantly enlarges the window of exploration in climate data assimilations.

Health messages on television commercials.

PubMed

Wallack, L; Dorfman, L

1992-01-01

Television is an important source of health information in the United States, yet little research has focused on the presentation of general health issues on television. This preliminary study reports on the health-related content of television commercials found on a typical television day. We conducted a content analysis of a composite day of television comprising 20 hours randomly selected over a three week period (April-May 1989). Findings are presented regarding health messages found in commercial time--advertisements, public service announcements (PSAs), editorials, and promotions for upcoming programs. Overall, 31% of the 654 commercial spots contained health messages. Most health messages were claims of good nutrition in food and beverage advertisements. PSAs comprise 1.4% of the 20-hour sample and 5.8% of the commercial time. Health messages appeared in 38% of PSAs, accounting for less than seven minutes. Not one PSA addressed tobacco, alcohol, or diet--the three leading behavioral risk factors for poor health. PSAs are usually seen as a mechanism by which the public health community can alert the public to important health issues. Given the declining pool of PSA time, public health educators will need to seek alternative strategies for influencing television content, such as media advocacy. In addition, further research on audience interpretation and response to commercial messages is suggested.

76 FR 39043 - TRICARE; Reimbursement of Sole Community Hospitals and Adjustment to Reimbursement of Critical...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-05

... hospitals located within Military Treatment Facility (MTF) Prime Service Areas (PSAs) and deemed essential... costs. It has come to our attention that there may be some CAHs located in MTF PSAs that are deemed... proposing a CAH TMCPA for TRICARE network hospitals located within MTF PSAs and deemed essential for...

Fiber optical parametric amplifiers in optical communication systems

PubMed Central

Marhic (†), Michel E; Andrekson, Peter A; Petropoulos, Periklis; Radic, Stojan; Peucheret, Christophe; Jazayerifar, Mahmoud

2015-01-01

The prospects for using fiber optical parametric amplifiers (OPAs) in optical communication systems are reviewed. Phase-insensitive amplifiers (PIAs) and phase-sensitive amplifiers (PSAs) are considered. Low-penalty amplification at/or near 1 Tb/s has been achieved, for both wavelength- and time-division multiplexed formats. High-quality mid-span spectral inversion has been demonstrated at 0.64 Tb/s, avoiding electronic dispersion compensation. All-optical amplitude regeneration of amplitude-modulated signals has been performed, while PSAs have been used to demonstrate phase regeneration of phase-modulated signals. A PSA with 1.1-dB noise figure has been demonstrated, and preliminary wavelength-division multiplexing experiments have been performed with PSAs. 512 Gb/s have been transmitted over 6,000 km by periodic phase conjugation. Simulations indicate that PIAs could reach data rate x reach products in excess of 14,000 Tb/s × km in realistic wavelength-division multiplexed long-haul networks. Technical challenges remaining to be addressed in order for fiber OPAs to become useful for long-haul communication networks are discussed. PMID:25866588

Celebrity Appeal: Reaching Women to Promote Colorectal Cancer Screening

PubMed Central

Cooper, Crystale Purvis; Gelb, Cynthia A.; Lobb, Kathleen

2015-01-01

The Centers for Disease Control and Prevention’s Screen for Life: National Colorectal Cancer Action Campaign works with the Entertainment Industry Foundation’s National Colorectal Cancer Research Alliance to develop public service announcements (PSAs) featuring celebrities. Selection of Screen for Life celebrity spokespersons is based on a variety of factors, including their general appeal and personal connection to colorectal cancer. Screen for Life PSAs featuring celebrities have been disseminated exclusively through donated media placements and have been formatted for television, radio, print, and out-of-home displays such as dioramas in airports, other transit stations, and shopping malls. A 2012 national survey with women aged 50–75 years (n = 772) investigated reported exposure to Screen for Life PSAs featuring actor Terrence Howard. In total, 8.3% of women recalled exposure to the PSAs. Celebrity spokespersons can attract the attention of both target audiences and media gatekeepers who decide which PSAs will receive donated placements. PMID:25521047

Effect of Character-Audience Similarity on the Perceived Effectiveness of Anti-Smoking PSAs via Engagement

PubMed Central

Kim, Minji; Shi, Rui; Cappella, Joseph N.

2016-01-01

This study assesses the impact of character-audience similarity, a core aspect of tailored communication, on evaluation of anti-smoking public service announcements (PSAs). Smoker and persuader characters are distinguished to explore their different roles in message effectiveness. Daily adult smokers (n = 1,160) were exposed to four video PSAs randomly selected from a larger pool. Similarity scores were determined from matching in demographic (age, gender, race) and motivational factors (quitting status) between the audience and the PSA’s characters. Results show that PSAs featuring distinctive smoker and/or persuader characters yielded significantly higher message engagement and perceived effectiveness (PE) than PSAs without characters. Given the presence of characters, smoker-audience similarity was positively associated with the engagement, which in turn enhanced PE. Persuader-audience similarity failed to predict increases in either engagement or PE. PMID:26891148

Celebrity appeal: reaching women to promote colorectal cancer screening.

PubMed

Cooper, Crystale Purvis; Gelb, Cynthia A; Lobb, Kathleen

2015-03-01

The Centers for Disease Control and Prevention's Screen for Life: National Colorectal Cancer Action Campaign works with the Entertainment Industry Foundation's National Colorectal Cancer Research Alliance to develop public service announcements (PSAs) featuring celebrities. Selection of Screen for Life celebrity spokespersons is based on a variety of factors, including their general appeal and personal connection to colorectal cancer. Screen for Life PSAs featuring celebrities have been disseminated exclusively through donated media placements and have been formatted for television, radio, print, and out-of-home displays such as dioramas in airports, other transit stations, and shopping malls. A 2012 national survey with women aged 50-75 years (n=772) investigated reported exposure to Screen for Life PSAs featuring actor Terrence Howard. In total, 8.3% of women recalled exposure to the PSAs. Celebrity spokespersons can attract the attention of both target audiences and media gatekeepers who decide which PSAs will receive donated placements.

Borrowing to save: a critique of recent proposals to partially privatize Social Security.

PubMed

Dattalo, Patrick

2007-07-01

Concern over Social Security's forecasted long-run deficit is occurring at a time when the program has a short-term surplus. One proposed strategy to address this forecasted deficit is to allow the investment of a portion of payroll taxes into private savings accounts (PSAs). The author analyzes recent proposals for PSAs and concludes that PSAs are more likely to be a problem than a solution. Paradoxically, PSAs require the government to borrow to encourage current workers to save. The author recommends resources to help social workers remain informed about proposed program reforms and prepared to advocate for the concept of social insurance.

Usefulness of pressure-sensitive adhesives as a pretreatment material before application of topical drug formulations and a peeling tape for excess stratum corneum layers.

PubMed

Kikuchi, Keisuke; Todo, Hiroaki; Sugibayashi, Kenji

2014-01-01

Two unique pressure-sensitive adhesive (PSA) tapes (PSA-A, -B) with different adhesive properties of commercial PSAs were prepared and evaluated for their usefulness as a pretreatment material prior to the application of transdermal therapeutic systems or topical drug formulations and also as a peeling agent against excess layers of the stratum corneum. In the present study, in vitro permeation experiments were conducted using vertical type diffusion cells and excised hairless rat or porcine skin from which the stratum corneum had been stripped several times with PSAs. The results obtained revealed that PSA-A and -B had higher stripping or peeling effects than those of the marketed PSAs. Marked changes were observed in skin barrier function before and after stripping using PSAs, and the enhancement effect on the skin permeation of drugs achieved by stripping the stratum corneum was markedly different between the PSAs. PSA-A, in particular, markedly improved skin permeation and the skin concentration of topically applied chemical compounds because it removed many layers of the stratum corneum when skin was stripped only a few times. In contrast, when PSA-B was used to pretreat the skin surface, the extent of skin permeation and concentration of drugs was safely increased because only a few layers of the stratum corneum were removed, even with repeated stripping. The enhancement effect achieved by PSA-B was not as high as that by PSA-A. Thus, stripping with PSA-A can be used as a penetration enhancement tool, whereas PSA-B can be used as a peeling material against excess layers of the stratum corneum.

High-frequency filtering of strong-motion records

USGS Publications Warehouse

Douglas, J.; Boore, D.M.

2011-01-01

The influence of noise in strong-motion records is most problematic at low and high frequencies where the signal to noise ratio is commonly low compared to that in the mid-spectrum. The impact of low-frequency noise (5 Hz) on computed pseudo-absolute response spectral accelerations (PSAs). In contrast to the case of low-frequency noise our analysis shows that filtering to remove high-frequency noise is only necessary in certain situations and that PSAs can often be used up to 100 Hz even if much lower high-cut corner frequencies are required to remove the noise. This apparent contradiction can be explained by the fact that PSAs are often controlled by ground accelerations associated with much lower frequencies than the natural frequency of the oscillator because path and site attenuation (often modelled by Q and κ, respectively) have removed the highest frequencies. We demonstrate that if high-cut filters are to be used, then their corner frequencies should be selected on an individual basis, as has been done in a few recent studies.

The Effect of Marijuana Scenes in Anti-marijuana Public Service Announcements on Adolescents’ Evaluation of Ad Effectiveness

PubMed Central

Kang, Yahui; Cappella, Joseph N.; Fishbein, Martin

2014-01-01

This study explored the possible negative impact of a specific ad feature—marijuana scenes—on adolescents’ perception of ad effectiveness. A secondary data analysis was conducted on adolescents’ evaluations of 60 anti-marijuana public service announcements (PSAs) that were a part of national and state anti-drug campaigns directed at adolescents. The major finding of the study was that marijuana scenes in anti-marijuana PSAs negatively affected ad liking and thought valence toward the ads among adolescents who are at higher levels of risk for marijuana use. This negative impact was not reversed in the presence of strong anti-marijuana arguments. The results may be used to partially explain the lack of effectiveness of the anti-drug media campaign. It may also help us design more effective anti-marijuana PSAs by isolating adverse elements in the ads that may elicit boomerang effects in the target population. Limitations of the study and future directions were discussed. PMID:19735026

Suicide Prevention Public Service Announcements (PSAs): Examples from Around the World.

PubMed

Ftanou, Maria; Cox, Georgina; Nicholas, Angela; Spittal, Matthew J; Machlin, Anna; Robinson, Jo; Pirkis, Jane

2017-04-01

Media campaigns have received increased attention as an intervention for combating suicide. Suicide prevention campaigns involving public service announcements (PSAs) have not been well described and have been subject to minimal evaluation. This study aimed to identify suicide prevention PSAs from around the world and analyze and describe their content. We searched the Internet for short, English-language PSAs that had been screened as part of suicide prevention campaigns and identified 35. Most commonly, these PSAs focused on the general population and/or people who might be at risk of suicide, and had a particular emphasis on young people. Almost 60% promoted open discussion about suicide, around 50% indicated that the life of a suicidal person was important, about 40% acknowledged the suffering associated with suicidal thoughts and feelings, about 25% stressed that suicide is preventable, and about 20% focused on the devastating impact of suicide for those left behind. Most PSAs promoted some sort of support for people at risk of suicide, usually a helpline or website. Although these messages appeared appropriate and practical there is a lack of research on the impact that they may have on people with varying degrees of suicide risk. Further work is needed to ensure that they are consistent with theories of behavior change, and that they are having their desired impacts.

Reduced prefrontal and temporal processing and recall of high "sensation value" ads.

PubMed

Langleben, Daniel D; Loughead, James W; Ruparel, Kosha; Hakun, Jonathan G; Busch-Winokur, Samantha; Holloway, Matthew B; Strasser, Andrew A; Cappella, Joseph N; Lerman, Caryn

2009-05-15

Public service announcements (PSAs) are non-commercial broadcast ads that are an important part of televised public health campaigns. "Message sensation value" (MSV), a measure of sensory intensity of audio, visual, and content features of an ad, is an important factor in PSA impact. Some communication theories propose that higher message sensation value brings increased attention and cognitive processing, leading to higher ad impact. Others argue that the attention-intensive format could compete with ad's message for cognitive resources and result in reduced processing of PSA content and reduced overall effectiveness. Brain imaging during PSA viewing provides a quantitative surrogate measure of PSA impact and addresses questions of PSA evaluation and design not accessible with traditional subjective and epidemiological methods. We used Blood Oxygenation Level Dependent (BOLD) functional Magnetic Resonance Imaging (fMRI) and recognition memory measures to compare high and low MSV anti-tobacco PSAs and neutral videos. In a short-delay, forced-choice memory test, frames extracted from PSAs were recognized more accurately than frames extracted from the NV. Frames from the low MSV PSAs were better recognized than frames from the high MSV PSAs. The accuracy of recognition of PSA frames was positively correlated with the prefrontal and temporal, and negatively correlated with the occipital cortex activation. The low MSV PSAs were associated with greater prefrontal and temporal activation, than the high MSV PSAs. The high MSV PSAs produced greater activation primarily in the occipital cortex. These findings support the "dual processing" and "limited capacity" theories of communication that postulate a competition between ad's content and format for the viewers' cognitive resources and suggest that the "attention-grabbing" high MSV format could impede the learning and retention of an ad. These findings demonstrate the potential of using neuroimaging in the design and evaluation of mass media public health communications.

Earthquakes

MedlinePlus

... Situations Food and Water People with Special Needs PSAs and Podcasts Extreme Heat About Extreme Heat Protecting ... to Stay Cool Missouri Cooling Centers Extreme Heat PSAs Related Links MMWR Bibliography Floods Flood Readiness Personal ...

Oxytocin increases the influence of public service advertisements.

PubMed

Lin, Pei-Ying; Grewal, Naomi Sparks; Morin, Christophe; Johnson, Walter D; Zak, Paul J

2013-01-01

This paper presents a neurophysiologic model of effective public service advertisements (PSAs) and reports two experiments that test the model. In Experiment 1, we show that after watching 16 PSAs participants who received oxytocin, compared to those given a placebo, donated to 57% more causes, donated 56% more money, and reported 17% greater concern for those in the ads. In Experiment 2, we measured adrenocorticotropin hormone (ACTH) and oxytocin levels in blood before and after participants watched a PSA. As predicted by the model, donations occurred when participants had increases in both ACTH and oxytocin. Our results indicate that PSAs with social content that cause OT release will be more effective than those that do not. Our results also explain why some individuals do not respond to PSAs.

Effects of Online Comments on Smokers’ Perception of Anti-Smoking Public Service Announcements

PubMed Central

Shi, Rui; Messaris, Paul; Cappella, Joseph N.

2014-01-01

On YouTube anti-smoking PSAs are widely viewed and uploaded; they also receive extensive commentary by viewers. This study examined whether such evaluative comments with or without uncivil expressions influence evaluations by subsequent viewers. Results showed PSAs with positive (i.e. anti-smoking) comments were perceived by smokers as more effective than PSAs with negative (pro smoking) comments. Smokers in the no comment condition gave the highest perceived effectiveness score to PSAs. Smokers’ readiness to quit smoking moderated the effect of comments on PSA evaluation. Smokers reading negative uncivil comments reported more negative attitude toward quitting and a lower level of perceived risk of smoking than those reading negative civil comments but positive civil and positive uncivil comments didn't elicit different responses. PMID:25561825

Effects of Online Comments on Smokers' Perception of Anti-Smoking Public Service Announcements.

PubMed

Shi, Rui; Messaris, Paul; Cappella, Joseph N

2014-07-01

On YouTube anti-smoking PSAs are widely viewed and uploaded; they also receive extensive commentary by viewers. This study examined whether such evaluative comments with or without uncivil expressions influence evaluations by subsequent viewers. Results showed PSAs with positive (i.e. anti-smoking) comments were perceived by smokers as more effective than PSAs with negative (pro smoking) comments. Smokers in the no comment condition gave the highest perceived effectiveness score to PSAs. Smokers' readiness to quit smoking moderated the effect of comments on PSA evaluation. Smokers reading negative uncivil comments reported more negative attitude toward quitting and a lower level of perceived risk of smoking than those reading negative civil comments but positive civil and positive uncivil comments didn't elicit different responses.

Oxytocin Increases the Influence of Public Service Advertisements

PubMed Central

Lin, Pei-Ying; Grewal, Naomi Sparks; Morin, Christophe; Johnson, Walter D.; Zak, Paul J.

2013-01-01

This paper presents a neurophysiologic model of effective public service advertisements (PSAs) and reports two experiments that test the model. In Experiment 1, we show that after watching 16 PSAs participants who received oxytocin, compared to those given a placebo, donated to 57% more causes, donated 56% more money, and reported 17% greater concern for those in the ads. In Experiment 2, we measured adrenocorticotropin hormone (ACTH) and oxytocin levels in blood before and after participants watched a PSA. As predicted by the model, donations occurred when participants had increases in both ACTH and oxytocin. Our results indicate that PSAs with social content that cause OT release will be more effective than those that do not. Our results also explain why some individuals do not respond to PSAs. PMID:23460821

After a Wildfire

MedlinePlus

... Situations Food and Water People with Special Needs PSAs and Podcasts Extreme Heat About Extreme Heat Protecting ... to Stay Cool Missouri Cooling Centers Extreme Heat PSAs Related Links MMWR Bibliography Floods Flood Readiness Personal ...

Tsunamis: Sanitation and Hygiene

MedlinePlus

... Situations Food and Water People with Special Needs PSAs and Podcasts Extreme Heat About Extreme Heat Protecting ... to Stay Cool Missouri Cooling Centers Extreme Heat PSAs Related Links MMWR Bibliography Floods Flood Readiness Personal ...

78 FR 49272 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-13

... committee regarding classification of triple chamber pacing system analyzers (PSAs) with external pacing... chamber PSA is intended to be used during the implant procedure of pacemakers and defibrillators...

Heat Stress in Older Adults

MedlinePlus

... Situations Food and Water People with Special Needs PSAs and Podcasts Extreme Heat About Extreme Heat Protecting ... to Stay Cool Missouri Cooling Centers Extreme Heat PSAs Related Links MMWR Bibliography Floods Flood Readiness Personal ...

Food Safety After a Tsunami

MedlinePlus

... Situations Food and Water People with Special Needs PSAs and Podcasts Extreme Heat About Extreme Heat Protecting ... to Stay Cool Missouri Cooling Centers Extreme Heat PSAs Related Links MMWR Bibliography Floods Flood Readiness Personal ...

75 FR 68467 - Transportation for Individuals With Disabilities: Passenger Vessels

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-08

... (PSAs). They supported considering such animals to be service animals and opposed permitting emotional... of service animals encompasses PSAs. The preamble to the final rule made clear that ESAs, consistent...

47 CFR 73.671 - Educational and informational programming for children.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., specials, PSAs, short-form programs, and regularly scheduled non-weekly programs with a significant purpose..., specials, PSAs, short-form programs, and regularly scheduled non-weekly programs with a significant purpose...

47 CFR 74.790 - Permissible service of digital TV translator and LPTV stations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... public service announcements (PSAs) and to seeking or acknowledging financial support deemed necessary to... contributors. The originations concerning financial support and PSAs are limited to 30 seconds each, no more...

Know Stroke. Know the Signs. Act in Time.

MedlinePlus

... About the Campaign Stroke Materials » Brochures » Toolkits and Posters » Radio PSAs » Videos and TV PSAs » Widgets » Infographics ... are reported in the U.S. each year. The good news is that treatments are available that can ...

Affective and executive network processing associated with persuasive antidrug messages.

PubMed

Ramsay, Ian S; Yzer, Marco C; Luciana, Monica; Vohs, Kathleen D; MacDonald, Angus W

2013-07-01

Previous research has highlighted brain regions associated with socioemotional processes in persuasive message encoding, whereas cognitive models of persuasion suggest that executive brain areas may also be important. The current study aimed to identify lateral prefrontal brain areas associated with persuasive message viewing and understand how activity in these executive regions might interact with activity in the amygdala and medial pFC. Seventy adolescents were scanned using fMRI while they watched 10 strongly convincing antidrug public service announcements (PSAs), 10 weakly convincing antidrug PSAs, and 10 advertisements (ads) unrelated to drugs. Antidrug PSAs compared with nondrug ads more strongly elicited arousal-related activity in the amygdala and medial pFC. Within antidrug PSAs, those that were prerated as strongly persuasive versus weakly persuasive showed significant differences in arousal-related activity in executive processing areas of the lateral pFC. In support of the notion that persuasiveness involves both affective and executive processes, functional connectivity analyses showed greater coactivation between the lateral pFC and amygdala during PSAs known to be strongly (vs. weakly) convincing. These findings demonstrate that persuasive messages elicit activation in brain regions responsible for both emotional arousal and executive control and represent a crucial step toward a better understanding of the neural processes responsible for persuasion and subsequent behavior change.

Do Emotional Appeals in Public Service Advertisements Influence Adolescents' Intention to Reduce Consumption of Sugar-Sweetened Beverages?

PubMed

Bleakley, Amy; Jordan, Amy B; Hennessy, Michael; Glanz, Karen; Strasser, Andrew; Vaala, Sarah

2015-08-01

Mass media campaigns are a commonly used approach to reduce sugary drink consumption, which is linked to obesity in children and adolescents. The present study investigated the direct and mediated effects of emotional appeals in public service advertisements (PSAs) that aired between 2010 and 2012 on adolescents' intention to reduce their sugar-sweetened beverage (SSB) consumption. An online randomized experiment was conducted with a national sample of adolescent respondents ages 13 to 17 years old (N = 805). Participants were randomly assigned to 1 of 4 conditions. Three experimental conditions represented PSAs with different emotional appeals: humor, fear, and nurturance, plus a fourth control condition. The outcome was adolescents' intention to cut back on SSBs. The direct effect of fear appeals on intention was mediated through adolescents' perception of the PSAs' argument strength; perceived argument strength was also the key mediator for the indirect effects of humor and nurturance on intention. Several hypothesized mediators influenced by the appeals were not associated with intention. This is the first study to test the effect of persuasive emotional appeals used in SSB-related PSAs. The perceived strength of the PSAs' arguments is important to consider in the communication of messages designed to reduce SSB consumption.

77 FR 28566 - Notice of Request for a New Information Collection (Food Safety Education Campaign-Post-Wave...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-15

... practices. The public service announcements (PSAs) will also be described to respondents in order to gauge... campaign thus far and inform future rounds of PSAs. FSIS has made the following estimates based upon an...

Transdermal Nitroglycerin Delivery Using Acrylic Matrices: Design, Formulation, and In Vitro Characterization

PubMed Central

Ramazani Saadat Abadi, Ahmad

2014-01-01

Nitroglycerin (TNG) transdermal drug delivery systems (TDDSs) with different acrylic pressure-sensitive adhesives (PSAs) and chemical permeation enhancers (CPEs) were prepared. The effects of PSAs and CPEs types and concentrations on skin permeation and in vitro drug release from devices were evaluated using the dissolution method as well as the modified-jacketed Franz diffusion cells fitted with excised rat abdominal skin. It was demonstrated that the permeation rate or steady state flux (J ss) of the drug through the excised rat skin was dependent on the viscosity and type of acrylic PSA as well as the type of CPE. Among different acrylic PSAs, Duro-Tak 2516 and Duro-Tak 2054 showed the highest and Duro-Tak 2051 showed the lowest J ss. Among the various CPEs, propylene glycol and cetyl alcohol showed the highest and the lowest enhancement of the skin permeation of TNG, respectively. The adhesion properties of devices such as 180° peel strength and probe tack values were obtained. It was shown that increasing the concentration of CPE led to reduction in the adhesion property of PSA. Moreover, after optimization of the formulation, it was found that the use of 10% PG as a CPE and 25% nitroglycerin loading in Duro-Tak 2054 is an effective monolithic DIAP for the development of a transdermal therapeutic system for nitroglycerin. PMID:24511396

Trait- and pre-sleep-state-dependent arousal in insomnia disorders: what role may sleep reactivity and sleep-related metacognitions play? A pilot study.

PubMed

Palagini, Laura; Mauri, Mauro; Dell'Osso, Liliana; Riemann, Dieter; Drake, Christopher L

2016-09-01

Research into the cause of chronic insomnia has identified hyperarousal as a key factor, which is likely to have both trait and state components. Sleep-related cognition, metacognition, and sleep reactivity also play an important role in insomnia. Our aim was to investigate how these insomnia-related constructs are associated with trait predisposition and pre-sleep arousal in subjects with an insomnia disorder. Fifty-three individuals with insomnia disorder (according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) (F = 33; 52 + 10)) and 30 healthy controls (F = 18; 51.8 + 12 years) were evaluated with a set of questionnaires, including the Ford Insomnia Response to Stress Test (FIRST), Metacognition Questionnaire - Insomnia (MCQI), Arousal Predisposition Scale (APS), and Pre-sleep Arousal Scale (PSAS). Statistical analyses included multiple regression to elucidate the independent determinants of APS and PSAS. Participants with insomnia presented higher FIRST, MCQI, APS, PSAS scores (p-values <0.001) than healthy controls. In insomnia, APS and cognitive PSAS were best determined by MCQI (respectively, B = 0.09, p = 0.001, B = 0.08, p = 0.02), somatic PSAS by cognitive arousal (PSAS B = 0.35, p = 0.004) CONCLUSIONS: This study suggests that in insomnia disorders, trait predisposition toward hyperarousal and pre-sleep-cognitive-state-dependent arousal may be closely related to sleep-related metacognitive processes. Sleep-related metacognitive processes may be associated with trait hyperarousal within the framework of a mutual relationship, and could, in turn, modulate cognitive pre-sleep-state arousal. A broad range of cognitive and metacognitive processes should be considered when dealing with subjects with insomnia. Copyright © 2016 Elsevier B.V. All rights reserved.

Alcohol-control public service announcements (PSAs) and drunk-driving fatal accidents in the United States, 1996-2010.

PubMed

Niederdeppe, Jeff; Avery, Rosemary; Miller, Emily N

2017-06-01

Widespread concern regarding the detrimental effects of excessive alcohol consumption (especially by minors) and associated social problems (particularly drunk driving) continues to exist among policymakers, law enforcement officers, and the general public. Alcohol consumption is a leading contributor to death from injuries, which itself is one of the main causes of death for people under 21years of age in the United States. This study examines the relationship between the volume and timing of alcohol-control public service announcements (PSAs) and rates of drunk-driving fatal accidents in the U.S. We estimate ordinary least squares (OLS) regression models to predict rates of drunk-driving fatal accidents by state and month as a function of the volume of alcohol-control PSAs aired during the previous 8months. Models include controls for state anti-drunk-driving laws and regulations, state demographic characteristics, state taxes on alcohol, calendar year, and seasonality. Results indicate that higher volumes of anti-drunk driving PSAs airing in the preceding 2 to 3months are associated, albeit modest in magnitude, with reduced rates of drunk-driving fatal accidents. The regression coefficients are largest for adults (relative to underage drunk drivers) and when the PSAs air during prime time (relative to daytime or nighttime). We conclude that PSAs could play an important contributing role in reducing drunk-driving fatal accidents, although levels of exposure and potential effects likely remain modest due to reliance on donated air time. Well-funded anti-drunk driving campaigns could achieve higher levels of exposure and have a larger impact. Copyright © 2017 Elsevier Inc. All rights reserved.

75 FR 75486 - Maritime Security Directive 104-6 (Rev. 4); Guidelines for U.S. Vessels Operating in High Risk...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-03

... Directive 104-6 (series), we have developed piracy-related Port Security Advisories (PSAs) to provide... compliance with this directive. The PSAs can be found at http://homeport.uscg.mil/piracy , including a non...

75 FR 29358 - Maritime Security Directive 104-6 (Rev 2 and 3); Guidelines for U.S. Vessels Operating in High...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-25

... developed piracy-related Port Security Advisories (PSAs)to provide further guidance and direction to U.S. flagged vessels operating in high risk waters to help facilitate compliance with this directive. The PSAs...

I Saw It on TV. More Vocational Educators Use PSAs and Videos to Reach Potential Students.

ERIC Educational Resources Information Center

Maxwell, Bruce

1994-01-01

Discusses how a growing number of states and school districts are using public service announcements (PSAs) to recruit students. Describes how a world-class decathlete appeared for free in a PSA for the Idaho Division of Vocational Education. (JOW)

Visual Attention to Antismoking PSAs: Smoking Cues versus Other Attention-Grabbing Features

ERIC Educational Resources Information Center

Sanders-Jackson, Ashley N.; Cappella, Joseph N.; Linebarger, Deborah L.; Piotrowski, Jessica Taylor; O'Keeffe, Moira; Strasser, Andrew A.

2011-01-01

This study examines how addicted smokers attend visually to smoking-related public service announcements (PSAs) in adults smokers. Smokers' onscreen visual fixation is an indicator of cognitive resources allocated to visual attention. Characteristic of individuals with addictive tendencies, smokers are expected to be appetitively activated by…

Documentation and Validation of the Goddard Earth Observing System (GEOS) Data Assimilation System, Version 4

NASA Technical Reports Server (NTRS)

Suarez, Max J. (Editor); daSilva, Arlindo; Dee, Dick; Bloom, Stephen; Bosilovich, Michael; Pawson, Steven; Schubert, Siegfried; Wu, Man-Li; Sienkiewicz, Meta; Stajner, Ivanka

2005-01-01

This document describes the structure and validation of a frozen version of the Goddard Earth Observing System Data Assimilation System (GEOS DAS): GEOS-4.0.3. Significant features of GEOS-4 include: version 3 of the Community Climate Model (CCM3) with the addition of a finite volume dynamical core; version two of the Community Land Model (CLM2); the Physical-space Statistical Analysis System (PSAS); and an interactive retrieval system (iRET) for assimilating TOVS radiance data. Upon completion of the GEOS-4 validation in December 2003, GEOS-4 became operational on 15 January 2004. Products from GEOS-4 have been used in supporting field campaigns and for reprocessing several years of data for CERES.

Explicit and implicit effects of anti-marijuana and anti-tobacco TV advertisements.

PubMed

Czyzewska, Maria; Ginsburg, Harvey J

2007-01-01

Effects of anti-tobacco and anti-marijuana TV advertisements on explicit (i.e., semantic differential ratings) and implicit (i.e. Implicit Association Test, IAT) attitudes toward tobacco and marijuana were compared. Two hundred twenty nine, 18- to 19-year-old U.S. college students were randomly assigned to anti-tobacco or anti-marijuana PSA viewing conditions. Participants completed a short survey on attitudes to tobacco and marijuana. Afterwards they watched 15 PSAs embedded in a 15-min science program. At the end, all participants completed IAT for marijuana, IAT for tobacco and the assessment of explicit attitudes. Results of ANCOVA revealed a significant interaction between type of TV PSAs watched and implicit attitudes, F(1,223)=7.12, p<0.01 when controlling for preexisting attitudes to both substances; the implicit attitudes were more negative toward the substance that corresponded to the content of advertisements watched (i.e., anti-tobacco or anti-marijuana). However, analogical analysis on explicit measures showed that attitudes to marijuana became less negative among students that watched anti-marijuana ads than the group with anti-tobacco ads, F(1,222)=5.79, p<0.02. The discussion focused on the practical and theoretical implications of the observed dissociation between implicit and explicit attitudes to marijuana after the exposure to anti-marijuana PSAs.

42 CFR 414.66 - Incentive payments for physician scarcity areas.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Physician Scarcity Area (PSA) for primary or specialist care are eligible for a 5 percent incentive payment. (c) Primary care physicians furnishing services in primary care PSAs are entitled to an additional 5... section 1861(r)(1) of the Act, furnishing services in specialist care PSAs are entitled to an additional 5...

Pre-Production Planning for Public Service Announcements: A Case Study.

ERIC Educational Resources Information Center

Johnson, Mark

To investigate the factors behind the overall lack of success of televised public service announcements (PSAs), five Marine recruitment PSAs were studied using 138 college undergraduate students (75% male and 90% freshmen and sophomores). Results indicated the following: in general, the PSA messages were perceived as alienating by the students;…

Audience Recall of AIDS PSAs among U.S. and International College Students.

ERIC Educational Resources Information Center

Lee, Jung-Sook; Davie, William R.

1997-01-01

Shows that audience recall of AIDS public service announcements (PSAs) is related to message appeal types, cultural identity, and gender. Finds that strong emotional appeals are better remembered than rational ones; U.S. viewers recalled more than international participants; and college women recalled more than college men in general, and…

Sensation Seeking and Targeting of Televised Anti-Drug PSAs.

ERIC Educational Resources Information Center

Donohew, Lewis; And Others

A study was conducted to determine how to reach out in an effective manner via televised public service announcements (PSAs) to particular at-risk audiences to motivate participation in drug abuse prevention programs. The subjects (207 young adults in Fayette County, Kentucky) responded to the M. Zuckerman sensation-seeking questionnaire. They…

Donated television airplay of colorectal cancer education public service announcements--United States, 1999-2002.

PubMed

2003-03-14

To help communicate the importance of colorectal cancer (CRC) screening, in 1999, the U.S. Department of Health and Human Services (DHHS) launched the "Screen for Life: National Colorectal Cancer Action Campaign" (SFL) (http://www.cdc.gov/cancer/screenforlife) as one of many strategies addressing the prevention and early detection of CRC. As a central part of this campaign, public service announcements (PSAs) were developed to take advantage of the influence and reach of television to encourage Americans aged > or = 50 years to get tested for CRC. This report summarizes an assessment of donated television airplay that SFL PSAs received during March 1999-February 2002. According to data obtained from Arbitron Inc., a research firm that monitors broadcast media in the United States, SFL PSAs were broadcast 41,624 times, amounting to approximately 4.3 million dollars in donated television airtime. As DHHS and others promote CRC screening, CDC will continue to release and track airplay of SFL PSAs and examine the collective influence that SFL and other educational efforts and strategies have on CRC screening rates in the United States.

Effect of amphiphilic additives on the behavior of water-based acrylic pressure-sensitive adhesives during paper recycling

Treesearch

Jihui Guo; Steven J. Severtson; Larry E. Gwin; Carl J. Houtman

2008-01-01

Pressure-sensitive adhesives (PSAs) in recovered paper reduce efficiency and increase operating costs for paper recycling mills. Increased PSA fragmentation during pulping and the corresponding reduction in screening efficiency are indications that a PSA will likely interfere with paper recycling. Water-based PSAs, which dominate the label market, have complex...

Does the Impact of Anti-Drinking and Driving Public Service Announcements Differ Based on Message Type and Viewer Characteristics?

ERIC Educational Resources Information Center

Santa, Annesa Flentje; Cochran, Bryan N.

2008-01-01

The purpose of this study was to inform future Public Service Announcement (PSA) development by examining the potential effectiveness of different types of anti-driving under the influence (DUI) PSAs for persons with different characteristics. PSAs utilizing empathy, fear, and informational approaches were shown to persons recruited from…

A mechanics approach to the study of pressure sensitive adhesives and human skin for transdermal drug delivery applications

NASA Astrophysics Data System (ADS)

Taub, Marc Barry

Transdermal drug delivery is an alternative approach to the systemic delivery of pharmaceuticals where drugs are administered through the skin and absorbed percutaneously. This method of delivery offers several advantages over more traditional routes; most notably, the avoidance of the fast-pass metabolism of the liver and gut, the ability to offer controlled release rates, and the possibility for novel devices. Pressure sensitive adhesives (PSAs) are used to bond transdermal drug delivery devices to the skin because of their good initial and long-term adhesion, clean removability, and skin and drug compatibility. However, an understanding of the mechanics of adhesion to the dermal layer, together with quantitative and reproducible test methods for measuring adhesion, have been lacking. This study utilizes a mechanics-based approach to quantify the interfacial adhesion of PSAs bonded to selected substrates, including human dermal tissue. The delamination of PSA layers is associated with cavitation in the PSA followed by the formation of an extensive cohesive zone behind the debond tip. A quantitative metrology was developed to assess the adhesion and delamination of PSAs, such that it could be possible to easily distinguish between the adhesive characteristics of different PSA compositions and to provide a quantitative basis from which the reliability of adhesive layers bonded to substrates could be studied. A mechanics-based model was also developed to predict debonding in terms of the relevant energy dissipation mechanisms active during this process. As failure of transdermal devices may occur cohesively within the PSA layer, adhesively at the interface between the PSA and the skin, or cohesively between the corneocytes that comprise the outermost layer of the skin, it was also necessary to explore the mechanical and fracture properties of human skin. The out-of-plane delamination of corneocytes was studied by determining the strain energy release rate during debonding of cantilever-beam specimens containing thin layers of human dermal tissue at their midline. Finally, the interfacial adhesion of PSAs bonded to human skin was studied and the mechanics model that was developed for PSA failure was extended to provide the capability for in vivo reliability predictions for transdermal systems bonded to human skin.

A Survey of Online and Mobile Technology Use at Peer Support Agencies.

PubMed

Aschbrenner, Kelly A; Naslund, John A; Grinley, Thomas; Bienvenida, John Carlo M; Bartels, Stephen J; Brunette, Mary

2018-01-04

Understanding how individuals with mental illness who receive services at peer support agencies use technology can inform the development of online and mobile health interventions tailored for users in these non-traditional mental health settings. The purpose of this study was to assess the use of technology among individuals with mental illness at peer support agencies. A survey delivered within peer support agencies (PSAs) in one state assessed technology use among individuals ages 18 and over with a self-identified mental illness receiving services at these agencies. In total, 195 individuals from 10 PSAs completed the survey. Eighty-two percent of respondents used the internet, with 63% of respondents connected to the internet at the PSAs. Eighty one percent of respondents owned a cell phone, 70% used text messaging, 58% owned smartphones, 61% used mobile applications, and 72% used social media. PSA users under age 55 were significantly more likely to own a smartphone than PSA users age 55 and older. Among internet users, 71% had searched for health information online and 57% had searched for mental health information online. Many individuals who receive services at PSAs have access to online and mobile technologies. These technologies may be leveraged to expand the reach of evidence-based health and mental health programs to individuals in these non-traditional mental health settings. Future research should explore the feasibility of intervention strategies that involve PSAs as a resource for linking people with mental illness to online and mobile support for their health and wellness goals.

Questioning the Value of Realism: Young Adults' Processing of Messages in Alcohol-Related Public Service Announcements and Advertising.

ERIC Educational Resources Information Center

Andsager, Julie L.; Austin, Erica Weintraub; Pinkleton, Bruce E.

2001-01-01

Finds that: (1) perceived realism and themes that students could identify with are important factors in increasing the salience and persuasiveness of alcohol-related public service announcements (PSAs) among undergraduate students; (2) realistic but logic-based PSAs were not as effective as unrealistic but enjoyable ads; and (3) low production…

Borrowing to Save: A Critique of Recent Proposals to Partially Privatize Social Security

ERIC Educational Resources Information Center

Dattalo, Patrick

2007-01-01

Concern over Social Security's forecasted long-run deficit is occurring at a time when the program has a short-term surplus. One proposed strategy to address this forecasted deficit is to allow the investment of a portion of payroll taxes into private savings accounts (PSAs). The author analyzes recent proposals for PSAs and concludes that PSAs…

Development of a Streamlined Work Flow for Handling Patients' Genetic Testing Insurance Authorizations.

PubMed

Uhlmann, Wendy R; Schwalm, Katie; Raymond, Victoria M

2017-08-01

Obtaining genetic testing insurance authorizations for patients is a complex, time-involved process often requiring genetic counselor (GC) and physician involvement. In an effort to mitigate this complexity and meet the increasing number of genetic testing insurance authorization requests, GCs formed a novel partnership with an industrial engineer (IE) and a patient services associate (PSA) to develop a streamlined work flow. Eight genetics clinics and five specialty clinics at the University of Michigan were surveyed to obtain benchmarking data. Tasks needed for genetic testing insurance authorization were outlined and time-saving work flow changes were introduced including 1) creation of an Excel password-protected shared database between GCs and PSAs, used for initiating insurance authorization requests, tracking and follow-up 2) instituting the PSAs sending GCs a pre-clinic email noting each patients' genetic testing insurance coverage 3) inclusion of test medical necessity documentation in the clinic visit summary note instead of writing a separate insurance letter and 4) PSAs development of a manual with insurance providers and genetic testing laboratories information. These work flow changes made it more efficient to request and track genetic testing insurance authorizations for patients, enhanced GCs and PSAs communication, and reduced tasks done by clinicians.

Characterization of Proteoforms with Unknown Post-translational Modifications Using the MIScore

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kou, Qiang; Zhu, Binhai; Wu, Si

Various proteoforms may be generated from a single gene due to primary structure alterations (PSAs) such as genetic variations, alternative splicing, and post-translational modifications (PTMs). Top-down mass spectrometry is capable of analyzing intact proteins and identifying patterns of multiple PSAs, making it the method of choice for studying complex proteoforms. In top-down proteomics, proteoform identification is often performed by searching tandem mass spectra against a protein sequence database that contains only one reference protein sequence for each gene or transcript variant in a proteome. Because of the incompleteness of the protein database, an identified proteoform may contain unknown PSAs comparedmore » with the reference sequence. Proteoform characterization is to identify and localize PSAs in a proteoform. Although many software tools have been proposed for proteoform identification by top-down mass spectrometry, the characterization of proteoforms in identified proteoform-spectrum matches still relies mainly on manual annotation. We propose to use the Modification Identification Score (MIScore), which is based on Bayesian models, to automatically identify and localize PTMs in proteoforms. Experiments showed that the MIScore is accurate in identifying and localizing one or two modifications.« less

48 CFR 601.603-3 - Appointment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (PSAs) are limited to the following: (1) The Human Resources Officer; (2) The Human Resources/Financial... perform human resource functions. [59 FR 66752, Dec. 28, 1994, as amended at 64 FR 43620, Aug. 11, 1999... ACQUISITION REGULATIONS SYSTEM Career Development, Contracting Authority, and Responsibilities 601.603-3...

Task Decomposition in Human Reliability Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boring, Ronald Laurids; Joe, Jeffrey Clark

2014-06-01

In the probabilistic safety assessments (PSAs) used in the nuclear industry, human failure events (HFEs) are determined as a subset of hardware failures, namely those hardware failures that could be triggered by human action or inaction. This approach is top-down, starting with hardware faults and deducing human contributions to those faults. Elsewhere, more traditionally human factors driven approaches would tend to look at opportunities for human errors first in a task analysis and then identify which of those errors is risk significant. The intersection of top-down and bottom-up approaches to defining HFEs has not been carefully studied. Ideally, both approachesmore » should arrive at the same set of HFEs. This question remains central as human reliability analysis (HRA) methods are generalized to new domains like oil and gas. The HFEs used in nuclear PSAs tend to be top-down— defined as a subset of the PSA—whereas the HFEs used in petroleum quantitative risk assessments (QRAs) are more likely to be bottom-up—derived from a task analysis conducted by human factors experts. The marriage of these approaches is necessary in order to ensure that HRA methods developed for top-down HFEs are also sufficient for bottom-up applications.« less

Institutional Branding: A Content Analysis of Public Service Announcements from American Universities

ERIC Educational Resources Information Center

Clayton, Michael J.; Cavanagh, Kevin V.; Hettche, Matt

2012-01-01

American universities receive millions of dollars worth of media exposure every year via Public Service Announcements (PSAs) broadcast during their respective school's athletic competitions. This research explores the message strategies and executional devices used by NCAA FBS (National Collegiate Athletic Association Football Bowl Subdivision)…

College Students' Knowledge, Attitudes and Adherence to Public Service Announcements on Ebola in Nigeria: Suggestions for Improving Future Ebola Prevention Education Programmes

ERIC Educational Resources Information Center

Ajilore, Kolade; Atakiti, Ifeoluwa; Onyenankeya, Kevin

2017-01-01

Introduction: Apprehension over a possible recurrence of Ebola remains pervasive among college students in Nigeria. Prevention education continues to be carried out through public service announcements (PSAs) on radio, television and in the social media. However, little is known about college students' knowledge, attitudes and adherence to PSAs on…

Examining the Usefulness of Student-Produced PSAs to Learn Advocacy in a Human Behavior and the Social Environment Course

ERIC Educational Resources Information Center

Chu, Yee Han; Quinn, Andrew

2018-01-01

Advocacy is a complex set of applications that applies knowledge of human behavior in the social environment to promote the rights of others. The purpose of this study was to explore the usefulness of student-created public service announcements (PSAs) to help BSW students learn cause-based advocacy. Our results suggest that assigning a PSA…

Do Low Income Youth of Color See "The Bigger Picture" When Discussing Type 2 Diabetes: A Qualitative Evaluation of a Public Health Literacy Campaign.

PubMed

Schillinger, Dean; Tran, Jessica; Fine, Sarah

2018-04-24

As Type 2 diabetes spikes among minority and low-income youth, there is an urgent need to tackle the drivers of this preventable disease. The Bigger Picture (TBP) is a counter-marketing campaign using youth-created, spoken-word public service announcements (PSAs) to reframe the epidemic as a socio-environmental phenomenon requiring communal action, civic engagement and norm change. We examined whether and how TBP PSAs advance health literacy among low-income, minority youth. We showed nine PSAs, asking individuals open-ended questions via questionnaire, then facilitating a focus group to reflect upon the PSAs. Questionnaire responses revealed a balance between individual vs. public health literacy. Some focused on individual responsibility and behaviors, while others described socio-environmental forces underlying risk. The focus group generated a preponderance of public health literacy responses, emphasizing future action. Striking sociopolitical themes emerged, reflecting tensions minority and low-income youth experience, such as entrapment vs. liberation. Our findings speak to the structural barriers and complexities underlying diabetes risk, and the ability of spoken word medium to make these challenges visible and motivate action. Delivering TBP content to promote interactive reflection has potential to change behavioral norms and build capacity to confront the social, economic and structural factors that influence behaviors.

Drinking and Driving PSAs: A Content Analysis of Behavioral Influence Strategies.

ERIC Educational Resources Information Center

Slater, Michael D.

1999-01-01

Study randomly samples 66 drinking and driving television public service announcements that were then coded using a categorical and dimensional scheme. Data set reveals that informational/testimonial messages made up almost half of the total; positive appeals were the next most common, followed by empathy, fear, and modeling appeals. (Contains 34…

An alternative method for determining particle-size distribution of forest road aggregate and soil with large-sized particles

Treesearch

Hakjun Rhee; Randy B. Foltz; James L. Fridley; Finn Krogstad; Deborah S. Page-Dumroese

2014-01-01

Measurement of particle-size distribution (PSD) of soil with large-sized particles (e.g., 25.4 mm diameter) requires a large sample and numerous particle-size analyses (PSAs). A new method is needed that would reduce time, effort, and cost for PSAs of the soil and aggregate material with large-sized particles. We evaluated a nested method for sampling and PSA by...

NASA y Tú (NASA and You) - NASA's partnership with UNIVISION to promote Science, Technology, Engineering, and Math (STEM) careers among Hispanic youth

NASA Astrophysics Data System (ADS)

Colon-Robles, M.; Gilman, I.; Verstynen, S.; Jaramillo, R.; Bednar, S.; Shortridge, T.; Bravo, J.; Bowers, S.

2010-12-01

NASA is working with Univision Communications Inc. in support of the Spanish-language media outlet's initiative to improve high school graduation rates, prepare Hispanic students for college, and encourage them to pursue careers in science, technology, engineering and mathematics, or STEM, disciplines. A total of 52 Public Service Announcements (PSAs) named “Visión NASA” or “Vision: NASA” are being developed by NASA centered on current innovative technologies from all four NASA mission directorates (Science, Exploration Systems, Space Operations, and Aerodynamics). Public service announcements are being produced from scratch in both English and Spanish for a total of 26 announcements in each language. Interviews were conducted with NASA Hispanic Scientists or Engineers on the selected PSAs topics to both supply information on their subject matter and to serve as role models for Hispanic youth. Each topic selected for the PSAs has an accompanying website which includes the announcements, interviews with a Hispanic scientists or engineers, background information on the topic, and educational resources for students, parents and teachers. Products developed through this partnership will be presented including the websites of each PSA and their accompanying educational resources. The use of these educational resources for professional development, outreach and informal events, and for in-classroom uses will also be presented. This collaboration with Univision complements NASA's current education efforts to engage underrepresented and underserved students in the critical STEM fields.

Do Low Income Youth of Color See “The Bigger Picture” When Discussing Type 2 Diabetes: A Qualitative Evaluation of a Public Health Literacy Campaign

PubMed Central

Schillinger, Dean; Tran, Jessica; Fine, Sarah

2018-01-01

As Type 2 diabetes spikes among minority and low-income youth, there is an urgent need to tackle the drivers of this preventable disease. The Bigger Picture (TBP) is a counter-marketing campaign using youth-created, spoken-word public service announcements (PSAs) to reframe the epidemic as a socio-environmental phenomenon requiring communal action, civic engagement and norm change. Methods: We examined whether and how TBP PSAs advance health literacy among low-income, minority youth. We showed nine PSAs, asking individuals open-ended questions via questionnaire, then facilitating a focus group to reflect upon the PSAs. Results: Questionnaire responses revealed a balance between individual vs. public health literacy. Some focused on individual responsibility and behaviors, while others described socio-environmental forces underlying risk. The focus group generated a preponderance of public health literacy responses, emphasizing future action. Striking sociopolitical themes emerged, reflecting tensions minority and low-income youth experience, such as entrapment vs. liberation. Conclusion: Our findings speak to the structural barriers and complexities underlying diabetes risk, and the ability of spoken word medium to make these challenges visible and motivate action. Practice Implications: Delivering TBP content to promote interactive reflection has potential to change behavioral norms and build capacity to confront the social, economic and structural factors that influence behaviors. PMID:29695114

Selling College: A Longitudinal Study of American College Football Bowl Game Public Service Announcements

ERIC Educational Resources Information Center

Tobolowsky, Barbara F.; Lowery, John Wesley

2014-01-01

Using ideological analysis as a frame, researchers analyzed institutionally created commercials (PSAs) that appeared in 28 U.S. college football bowl games over a seven-year period (2003-2009) to better understand the universities' brands as represented in these advertisements. They found many common elements such as showing traditional…

Distraction Effects of Smoking Cues in Antismoking Messages: Examining Resource Allocation to Message Processing as a Function of Smoking Cues and Argument Strength

PubMed Central

Lee, Sungkyoung; Cappella, Joseph N.

2014-01-01

Findings from previous studies on smoking cues and argument strength in antismoking messages have shown that the presence of smoking cues undermines the persuasiveness of antismoking public service announcements (PSAs) with weak arguments. This study conceptualized smoking cues (i.e., scenes showing smoking-related objects and behaviors) as stimuli motivationally relevant to the former smoker population and examined how smoking cues influence former smokers’ processing of antismoking PSAs. Specifically, by defining smoking cues and the strength of antismoking arguments in terms of resource allocation, this study examined former smokers’ recognition accuracy, memory strength, and memory judgment of visual (i.e., scenes excluding smoking cues) and audio information from antismoking PSAs. In line with previous findings, the results of the study showed that the presence of smoking cues undermined former smokers’ encoding of antismoking arguments, which includes the visual and audio information that compose the main content of antismoking messages. PMID:25477766

Targeting anti-smoking messages: Does audience race matter?

PubMed Central

Tharp-Taylor, Shannah; Fryer, Craig S.; Shadel, William G.

2012-01-01

This study examined whether an adolescent’s self-identified race moderates the perceived effectiveness of anti-smoking messages. A sample of 94 never smoking adolescents (59% African-American; 41% European-American) participated in this two-part study. First, they rated the persuasive strength of a series of five decontextualized anti-smoking messages (i.e., messages delivered in text format). Second, they were exposed to five sets of anti-smoking public service announcements (PSAs; viewed as TV advertisements) that had embedded in them the five anti-smoking messages used in the first part of the study and rated their smoking refusal self-efficacy after each one. Although race moderated participants’ ratings of the decontextualized messages, there were no significant moderating effects of race when those messages were embedded in PSAs. The results of this study support the notion that anti-smoking PSAs should not be targeted to adolescent racial background, but suggests that decontextualized anti-smoking messages may be more effective if targeted to adolescent race. PMID:22481049

Just Add a Verse from the Quran: Effects of Religious Rhetoric in Gain- and Loss-Framed Anti-Alcohol Messages with a Palestinian Sample.

PubMed

Alhabash, Saleem; Almutairi, Nasser; Rub, Mohammad Abu

2017-10-01

This experiment investigated the effects of message framing (gain vs. loss) and religious rhetoric (religious vs. non-religious) on the expression of anti-alcohol civic intentions with a sample (N = 80) of Palestinian young adults. Results showed that the main effects of message framing (gain > loss) and religious rhetoric (non-religious > religious) on anti-alcohol civic intentions were significant. Furthermore, the study showed that viral behavioral intentions were strongly and significantly associated with expressing anti-alcohol civic intentions, with larger explanatory power for gain-framed PSAs that used a religious rhetoric. Additionally, a serial mediation model showed that the effect of religious rhetoric on anti-alcohol civic intentions was successfully mediated by the serial combination of attitudes toward the PSA and viral behavioral intention for gain-framed PSAs, but not for loss-framed PSAs. Findings are discussed within the framework of persuasion models.

Tu Amigo Pepe: Evaluation of a Multi-media Marketing Campaign that Targets Young Latino Immigrant MSM with HIV Testing Messages.

PubMed

Solorio, Rosa; Norton-Shelpuk, Pamela; Forehand, Mark; Montaño, Daniel; Stern, Joshua; Aguirre, Joel; Martinez, Marcos

2016-09-01

Latino immigrant men who have sex with men (MSM) are at risk for HIV and delayed diagnosis in the United States. This paper describes the evaluation of a pilot of the Tu Amigo Pepe, a multimedia HIV testing campaign aimed at Latino MSM in Seattle, WA particularly targeting immigrants who may not identify as gay, ages 18-30 years old. The 16-week campaign included Spanish-language radio public service announcements (PSAs), a Web site, social media outreach, a reminder system using mobile technology, print materials and a toll-free hotline. In developing the PSAs, the Integrated Behavioral Model was used as a framework to reframe negative attitudes, beliefs and norms towards HIV testing with positive ones as well as to promote self-efficacy towards HIV testing. The campaign had a significant and immediate impact on attitudes, beliefs, norms and self-efficacy towards HIV testing as well as on actual behavior, with HIV testing rates increasing over time.

Bulk & Interfacial Contributions to the Adhesion of Acrylic Emulsion-Based Pressure Sensitive Adhesives

NASA Astrophysics Data System (ADS)

Wang, Qifeng

The performance of pressure sensitive adhesives (PSAs) depends strongly on the viscoelastic properties of the adhesive material itself and the surface that it is placed into contact with. In this work we use a multiple- oscillatory test with microindentation apparatus that is able to quantify the mechanical response of adhesive materials in the linear regime, and also in the highly strained regime where the adhesive layer has cavitated to form mechanically isolated brils. The experiments involved the use of hemispherical indenters made of glass or polyethylene, brought into contact with a thin adhesive layer and then retracted, with comprehensive displacement history. A set of model acrylic emulsion-based PSAs were used in the experiments which show a suprising degree of elastic character at high strain. The experiment result suggest that an adhesive failure criterion based on the stored elastic energy is appropriate for these systems. The primary effect of the substrate is to modify the maximum strain where adhesive detachment from the indenter occurs.

Department of Defense Technical Architecture Framework for Information Management. Volume 1-8: Overview. Version 3.0.

DTIC Science & Technology

1996-04-30

CJCS Chairman of the Joint Chiefs of Staff CMP Configuration Management Plan COTS Commercial-off-the-Shelf DA Data Administrator DASD (IM) Deputy...Staff ( CJCS ) representing the unified combatant commands. " Technical: The system can evolve (migrate) to be supported by the integrated, standards...s) (PSAs), or CJCS , having functional responsibility for the missions and functions supported by the system, with the participation of affected DoD

Patterns of cortical activity during the observation of Public Service Announcements and commercial advertisings.

PubMed

Vecchiato, Giovanni; Astolfi, Laura; Cincotti, Febo; De Vico Fallani, Fabrizio; Sorrentino, Domenica M; Mattia, Donatella; Salinari, Serenella; Bianchi, Luigi; Toppi, Jlena; Aloise, Fabio; Babiloni, Fabio

2010-06-03

In the present research we were interested to study the cerebral activity of a group of healthy subjects during the observation a documentary intermingled by a series of TV advertisements. In particular, we desired to examine whether Public Service Announcements (PSAs) are able to elicit a different pattern of activity, when compared with a different class of commercials, and correlate it with the memorization of the showed stimuli, as resulted from a following subject's verbal interview. We recorded the EEG signals from a group of 15 healthy subjects and applied the High Resolution EEG techniques in order to estimate and map their Power Spectral Density (PSD) on a realistic cortical model. The single subjects' activities have been z-score transformed and then grouped to define four different datasets, related to subjects who remembered and forgotten the PSAs and to subjects who remembered and forgotten cars commercials (CAR) respectively, which we contrasted to investigate cortical areas involved in this encoding process. The results we here present show that the cortical activity elicited during the observation of the TV commercials that were remembered (RMB) is higher and localized in the left frontal brain areas when compared to the activity elicited during the vision of the TV commercials that were forgotten (FRG) in theta and gamma bands for both categories of advertisements (PSAs and CAR). Moreover, the cortical maps associated with the PSAs also show an increase of activity in the alpha and beta band. In conclusion, the TV advertisements that will be remembered by the experimental population have increased their cerebral activity, mainly in the left hemisphere. These results seem to be congruent with and well inserted in the already existing literature, on this topic, related to the HERA model. The different pattern of activity in different frequency bands elicited by the observation of PSAs may be justified by the existence of additional cortical networks processing these kind of audiovisual stimuli. Further research with an extended set of subjects will be necessary to further validate the observations reported in this paper.

Engaging Minority Youth in Diabetes Prevention Efforts Through a Participatory, Spoken-Word Social Marketing Campaign.

PubMed

Rogers, Elizabeth A; Fine, Sarah C; Handley, Margaret A; Davis, Hodari B; Kass, James; Schillinger, Dean

2017-07-01

To examine the reach, efficacy, and adoption of The Bigger Picture, a type 2 diabetes (T2DM) social marketing campaign that uses spoken-word public service announcements (PSAs) to teach youth about socioenvironmental conditions influencing T2DM risk. A nonexperimental pilot dissemination evaluation through high school assemblies and a Web-based platform were used. The study took place in San Francisco Bay Area high schools during 2013. In the study, 885 students were sampled from 13 high schools. A 1-hour assembly provided data, poet performances, video PSAs, and Web-based platform information. A Web-based platform featured the campaign Web site and social media. Student surveys preassembly and postassembly (knowledge, attitudes), assembly observations, school demographics, counts of Web-based utilization, and adoption were measured. Descriptive statistics, McNemar's χ 2 test, and mixed modeling accounting for clustering were used to analyze data. The campaign included 23 youth poet-created PSAs. It reached >2400 students (93% self-identified non-white) through school assemblies and has garnered >1,000,000 views of Web-based video PSAs. School participants demonstrated increased short-term knowledge of T2DM as preventable, with risk driven by socioenvironmental factors (34% preassembly identified environmental causes as influencing T2DM risk compared to 83% postassembly), and perceived greater personal salience of T2DM risk reduction (p < .001 for all). The campaign has been adopted by regional public health departments. The Bigger Picture campaign showed its potential for reaching and engaging diverse youth. Campaign messaging is being adopted by stakeholders.

Common themes from the extremes: using two methodologies to examine adolescents' perceptions of anti-violence public service announcements.

PubMed

Borzekowski, D L; Poussaint, A F

2000-03-01

To determine in what ways adolescents perceive public service announcements (PSAs) in general and, more specifically, anti-violence health messages. Seventy-nine adolescents who were involved with the issue of violence (39 pro-social, 40 incarcerated) participated. These youth were from four sites (Philadelphia, Pennsylvania, Detroit, Michigan, Albuquerque, New Mexico, and Portland, Oregon) and were chosen at random from a pool recommended by community leaders. First, adolescents were questioned on their demographics and knowledge of, attitudes about, and experience with, violence. Then, adolescents rated eight PSAs on levels of interest, understanding, believability, and perceived effect. In semistructured individual interviews, the adolescents discussed each of the PSAs as well as how health messages can effectively reach young people. We used quantitative and qualitative methodologies to analyze the data. Adolescents had similar opinions about the presented messages and using PSAs. Across both the pro-social and incarcerated groups, adolescents (a) opposed celebrity spokespeople, (b) preferred authentic-looking characters and realistic situations, (c) dismissed messages directed at either younger or older audiences, (d) confused abstractions, (e) focused on visuals, and (f) suggested using graphic images. The similarities observed between the pro-social and incarcerated adolescents may arise from the fact that, although the nature of their experience varied, both groups had high levels of issue involvement. From this study, we can make three recommendations for creating messages: (a) use authentic-looking characters in realistic situations; (b) employ simple, visual, and graphic messages; and (c) do formative evaluations with target audiences.

The SENSE Study: Treatment Mechanisms of a Cognitive Behavioral and Mindfulness-Based Group Sleep Improvement Intervention for At-Risk Adolescents.

PubMed

Blake, Matthew; Schwartz, Orli; Waloszek, Joanna M; Raniti, Monika; Simmons, Julian G; Murray, Greg; Blake, Laura; Dahl, Ronald E; Bootzin, Richard; McMakin, Dana L; Dudgeon, Paul; Trinder, John; Allen, Nicholas B

2017-06-01

The aim of this study was to test whether a cognitive behavioral and mindfulness-based group sleep intervention would improve sleep and anxiety on school nights in a sample of at-risk adolescents. We also examined whether benefits to sleep and anxiety would be mediated by improvements in sleep hygiene awareness and presleep hyperarousal. Secondary analysis of a randomized controlled trial conducted with 123 adolescent participants (female = 60%; mean age = 14.48) who had high levels of sleep problems and anxiety symptoms. Participants were randomized into a sleep improvement intervention (n = 63) or active control "study skills" intervention (n = 60). Preintervention and postintervention, participants completed the Pittsburgh Sleep Quality Index (PSQI), Spence Children's Anxiety Scale (SCAS), Sleep Beliefs Scale (SBS), and Presleep Hyperarousal Scale (PSAS) and wore an actiwatch and completed a sleep diary for five school nights. The sleep intervention condition was associated with significantly greater improvements in actigraphy-measured sleep onset latency (SOLobj), sleep diary measured sleep efficiency (SEsubj), PSQI, SCAS, SBS, and PSAS, with medium to large effect sizes. Improvements in the PSQI and SCAS were specifically mediated by the measured improvements in the PSAS that resulted from the intervention. Improvements in SOLobj and SEsubj were not specifically related to improvements in any of the putative treatment mechanisms. This study provides evidence that presleep arousal but not sleep hygiene awareness is important for adolescents' perceived sleep quality and could be a target for new treatments of adolescent sleep problems. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

Avoidance of anticipated regret: the ordering of prostate-specific antigen tests.

PubMed

Sorum, Paul C; Mullet, Etienne; Shim, Junseop; Bonnin-Scaon, Sylvie; Chasseigne, Gérard; Cogneau, Joël

2004-01-01

When making decisions, people are known to try to minimize the regret that would be provoked by unwanted consequences of these decisions. The authors explored the strength and determinants of such anticipated regret in a study of physicians' decisions to order prostate-specific antigen (PSA) tests. 32 US and 33 French primary care physicians indicated the likelihood they would order a PSA for 32 hypothetical men presenting for routine physical exams. They then indicated how much regret they would feel if they found advanced prostate cancer in 12 other patients for whom they had chosen not to order PSAs several years before. The latter patients differed according to age (55, 65, or 75 years), a prior request or not for PSA testing, and no or some irregularity of the prostate on the earlier rectal exam. ANOVA found that regret was higher when the patient had requested a PSA, the prostate was irregular, and the patient was younger. Shape had less effect when the patient had requested a PSA. US physicians had more regret than the French, patient request had a greater impact on the Americans, and increasing patient age reduced regret more among the French. In a 1-way correlation, the regret score was associated with the likelihood of ordering PSAs for both the French (r = 0.64, P < 0.005) and the Americans (r = 0.42, P< 0.02). In a regression analysis too, the regret score was the most important predictor of the likelihood of ordering a PSA (beta = 0.37, P < 0.0001). Regret over failing to diagnose aggressive prostate cancer is associated with a policy of ordering PSAs. This regret appears to be culturally sensitive.

An academic-marketing collaborative to promote depression care: a tale of two cultures.

PubMed

Kravitz, Richard L; Epstein, Ronald M; Bell, Robert A; Rochlen, Aaron B; Duberstein, Paul; Riby, Caroline H; Caccamo, Anthony F; Slee, Christina K; Cipri, Camille S; Paterniti, Debora A

2013-03-01

Commercial advertising and patient education have separate theoretical underpinnings, approaches, and practitioners. This paper aims to describe a collaboration between academic researchers and a marketing firm working to produce demographically targeted public service anouncements (PSAs) designed to enhance depression care-seeking in primary care. An interdisciplinary group of academic researchers contracted with a marketing firm in Rochester, NY to produce PSAs that would help patients with depressive symptoms engage more effectively with their primary care physicians (PCPs). The researchers brought perspectives derived from clinical experience and the social sciences and conducted empirical research using focus groups, conjoint analysis, and a population-based survey. Results were shared with the marketing firm, which produced four PSA variants targeted to gender and socioeconomic position. There was no simple, one-to-one relationship between research results and the form, content, or style of the PSAs. Instead, empirical findings served as a springboard for discussion and kept the creative process tethered to the experiences, attitudes, and opinions of actual patients. Reflecting research findings highlighting patients' struggles to recognize, label, and disclose depressive symptoms, the marketing firm generated communication objectives that emphasized: (a) educating the patient to consider and investigate the possibility of depression; (b) creating the belief that the PCP is interested in discussing depression and capable of offering helpful treatment; and (c) modelling different ways of communicating with physicians about depression. Before production, PSA prototypes were vetted with additional focus groups. The winning prototype, "Faces," involved a multi-ethnic montage of formerly depressed persons talking about how depression affected them and how they improved with treatment, punctuated by a physician who provided clinical information. A member of the academic team was present and consulted closely during production. Challenges included reconciling the marketing tradition of audience segmentation with the overall project goal of reaching as broad an audience as possible; integrating research findings across dimensions of words, images, music, and tone; and dealing with misunderstandings related to project scope and budget. Mixed methods research can usefully inform PSAs that incorporate patient perspectives and are produced to professional standards. However, tensions between the academic and commercial worlds exist and must be addressed. While rewarding, academic-marketing collaborations introduce tensions which must be addressed. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

An Academic-Marketing Collaborative to Promote Depression Care: A Tale of Two Cultures

PubMed Central

Kravitz, Richard L.; Epstein, Ronald M.; Bell, Robert A.; Rochlen, Aaron B.; Duberstein, Paul; Riby, Caroline H.; Caccamo, Anthony F.; Slee, Christina K.; Cipri, Camille S.; Paterniti, Debora A.

2011-01-01

Objectives Commercial advertising and patient education have separate theoretical underpinnings, approaches, and practitioners. This paper aims to describe a collaboration between academic researchers and a marketing firm working to produce demographically targeted public service anouncements (PSAs) designed to enhance depression care-seeking in primary care. Methods An interdisciplinary group of academic researcherss contracted with a marketing firm in Rochester, NY to produce PSAs that would help patients with depressive symptoms engage more effectively with their primary care physicians (PCPs). The researchers brought perspectives derived from clinical experience and the social sciences and conducted empirical research using focus groups, conjoint analysis, and a population-based survey. Results were shared with the marketing firm, which produced four PSA variants targeted to gender and socioeconomic position. Results There was no simple, one-to-one relationship between research results and the form, content, or style of the PSAs. Instead, empirical findings served as a springboard for discussion and kept the creative process tethered to the experiences, attitudes, and opinions of actual patients. Reflecting research findings highlighting patients’ struggles to recognize, label, and disclose depressive symptoms, the marketing firm generated communication objectives that emphasized: a) educating the patient to consider and investigate the possibility of depression; b) creating the belief that the PCP is interested in discussing depression and capable of offering helpful treatment; and c) modelling different ways of communicating with physicians about depression. Before production, PSA prototypes were vetted with additional focus groups. The winning prototype, “Faces,” involved a multi-ethnic montage of formerly depressed persons talking about how depression affected them and how they improved with treatment, punctuated by a physician who provided clinical information. A member of the academic team was present and consulted closely during production. Challenges included reconciling the marketing tradition of audience segmentation with the overall project goal of reaching as broad an audience as possible; integrating research findings across dimensions of words, images, music, and tone; and dealing with misunderstandings related to project scope and budget. Conclusion Mixed methods research can usefully inform PSAs that incorporate patient perspectives and are produced to professional standards. However, tensions between the academic and commercial worlds exist and must be addressed. Practice implications With certain caveats, implementation and dissemination researchers should consider opporutnities to join forces with marketing specialists. The results of such collaborations should be rigorously evaluated. PMID:21862274

Restless Genital Syndrome Induced by Milnacipran.

PubMed

Miyake, Keita; Takaki, Manabu; Sakamoto, Shinji; Kawada, Kiyohiro; Inoue, Shinichiro; Yamada, Norihito

Restless genital syndrome (RGS) includes discomfort, pain, numbness, vibration, restlessness, or a burning sensation involving the vagina, perineum, pelvis, penis, and proximal portion of the lower limbs in patients. The RGS has been sometimes reported in Parkinson disease. In patients without Parkinson disease, RGS is also known as persistent genital arousal disorder (PSAS), which includes uncontrollable genital arousal, with or without orgasm or genital engorgement, unrelated to sexual desire. Although withdrawal from selective serotonin reuptake inhibitors antidepressants is reported to induce PSAS, there is no report of RGS or PSAS induced by antidepressants. We obtained the consent for the presentation and have not identified individuals for ethical reasons. We first report a woman patient with depression induced RGS by milnacipran (MLN). We discuss the relationship with restless legs syndrome and the difference from akathisia. It is highly possible MLN affected her RGS because she experienced RGS for the first time after the dose of MLN was increased. A limitation of this report is that we stopped MLN and administered gabapentin enacarbil immediately. We should join MLN to the list of compounds suspected of inducing RGS.

Outcomes of Ultrasound-Guided Thrombin Injection of Nongroin Arterial Pseudoaneurysms.

PubMed

Valesano, Johnathan C; Schmitz, John J; Kurup, A Nicholas; Schmit, Grant D; Moynagh, Michael R; Atwell, Thomas D; Lewis, Bradley D; Lee, Robert A; Callstrom, Matthew R

2017-08-01

To evaluate success and complication rates of percutaneous ultrasound-guided thrombin injection of nongroin pseudoaneurysms (PSAs). Retrospective review of a prospectively maintained institutional database yielded 39 cases of arterial PSAs occurring at nongroin sites that were treated with percutaneous ultrasound-guided thrombin injection between 2000 and 2016 (average patient age 69.2 y ± 14.0). Of PSAs, 74.4% (29/39) arose in the upper extremities, and 92.3% (36/39) were iatrogenic. The brachial artery was the most commonly affected vessel (51.3% [20/39]), and arterial access was the most common cause (56.4% [22/39]). Average overall PSA size was 2.4 cm (range, 0.5-7.2 cm); average amount of thrombin injected was 320 IU (range, 50-2,000 IU). Technical success was defined as absence of flow within the PSA immediately after thrombin injection. Treatment success was defined as sustained thrombosis on follow-up imaging obtained at 1-3 days after treatment. Technical and treatment success rates of thrombin injections were 100% (39/39) and 84.8% (28/33), respectively. Longer term follow-up imaging (average 71 d; range, 12-201 d) was available for 7 of the treatment successes with 100% (7/7) showing sustained thrombosis. Comparing treatment successes and failures, there was no significant difference in average PSA size (2.3 cm vs 2.0 cm, P = .51) or average amount of thrombin injected (360 IU vs 180 IU, P = .14). There were no complications. Ultrasound-guided thrombin injection is a safe, efficacious treatment option for PSAs arising in nongroin locations. Copyright © 2017 SIR. Published by Elsevier Inc. All rights reserved.

Use of Pipeline™ embolization device for the treatment of traumatic intracranial pseudoaneurysms: Case series and review of cases from literature.

PubMed

Sami, Mairaj T; Gattozzi, Domenico A; Soliman, Hesham M; Reeves, Alan R; Moran, Christopher J; Camarata, Paul J; Ebersole, Koji C

2018-06-01

Intracranial traumatic pseudoaneurysms (PSA) are a rare but dangerous subtype of cerebral aneurysm. Reports documenting use of flow-diverting stents to treat traumatic intracranial PSAs are few and lack long-term follow-up. To our knowledge, this is the largest case-series to date demonstrating use of Pipeline Endovascular Device (PED) for traumatic intracranial PSAs. Retrospective review of 8 intracranial traumatic PSAs in 7 patients treated using only PED placement. Patients were followed clinically and angiographically for at least 6 months. Seven patients with a mean age of 37 years were treated for 8 intracranial pseudo-aneurysms between 2011-2015. Six aneurysms were the result of blunt trauma; 2 were from iatrogenic injury during transsphenoidal surgery. Mean clinical and angiographic follow-up in surviving patients was 15.2 months. In patients with angiographic follow-up, complete occlusion was achieved in all but one patient, who demonstrated near-complete occlusion. No ischemic events or stent-related stenosis were observed. One patient developed a carotid-cavernous fistula after PED, which was successfully retreated with placement of a second PED. There were two mortalities. One was due to suspected microwire perforation remote from the target aneurysm resulting in SAH/IPH. The other was due to a traumatic SDH and brainstem hemorrhage from an unrelated fall during follow-up interval. Use of PED for treatment of intracerebral PSAs following trauma or iatrogenic injury showed good persistent occlusion, and acceptable complication rate for this high-risk pathology. Risks of this procedure and necessary antiplatelet therapy require appropriate patient selection. Larger prospective studies are warranted. Copyright © 2018 Elsevier B.V. All rights reserved.

Incorporating Parallel Computing into the Goddard Earth Observing System Data Assimilation System (GEOS DAS)

NASA Technical Reports Server (NTRS)

Larson, Jay W.

1998-01-01

Atmospheric data assimilation is a method of combining actual observations with model forecasts to produce a more accurate description of the earth system than the observations or forecast alone can provide. The output of data assimilation, sometimes called the analysis, are regular, gridded datasets of observed and unobserved variables. Analysis plays a key role in numerical weather prediction and is becoming increasingly important for climate research. These applications, and the need for timely validation of scientific enhancements to the data assimilation system pose computational demands that are best met by distributed parallel software. The mission of the NASA Data Assimilation Office (DAO) is to provide datasets for climate research and to support NASA satellite and aircraft missions. The system used to create these datasets is the Goddard Earth Observing System Data Assimilation System (GEOS DAS). The core components of the the GEOS DAS are: the GEOS General Circulation Model (GCM), the Physical-space Statistical Analysis System (PSAS), the Observer, the on-line Quality Control (QC) system, the Coupler (which feeds analysis increments back to the GCM), and an I/O package for processing the large amounts of data the system produces (which will be described in another presentation in this session). The discussion will center on the following issues: the computational complexity for the whole GEOS DAS, assessment of the performance of the individual elements of GEOS DAS, and parallelization strategy for some of the components of the system.

Adherence performances of pressure sensitive adhesives on a model viscoelastic synthetic film: a tool for the understanding of adhesion on the human skin.

PubMed

Renvoise, Julien; Burlot, Delphine; Marin, Gérard; Derail, Christophe

2009-02-23

This work deals with the rheological behavior and adherence properties of pressure sensitive adhesive formulations dedicated to medical applications. We have developed a specific viscoelastic substrate which mimics adhesion on human skin to measure the adherence properties of PSAs when they are stuck on the human skin. By comparing peeling results of PSAs, dedicated to medical applications, stuck on human skin and on this viscoelastic substrate we show that this substrate, based on a blend of natural proteins, presents a better representation of the interactions occurring at the skin/adhesive interface than conventional substrates used for peel test (i.e. glass and steel).

Developing English and Spanish television public service announcements to promote colorectal cancer screening.

PubMed

Cooper, Crystale Purvis; Gelb, Cynthia A; Jameson, Heather; Macario, Everly; Jorgensen, Cynthia M; Seeff, Laura

2005-10-01

Screen for Life: National Colorectal Cancer Action Campaign (SFL) is a federally funded campaign to promote understanding of colorectal cancer and the importance of regular screening for adults aged 50 years and older. SFL uses a variety of communication strategies, including television public service announcements (PSAs). SFL materials are developed using the Health Communication Process endorsed by the U.S. Department of Health and Human Services, which has four stages: (a) planning and strategy development; (b) developing and pretesting concepts, messages, and materials; (c) implementing the program; and (d) assessing effectiveness and making refinements. This article describes SFL's application of this process to develop television PSAs in English and Spanish.

Bilateral persistent sciatic arteries complicated with chronic lower limb ischemia

PubMed Central

Wang, Bin; Liu, Zhenjie; Shen, Laigen

2011-01-01

INTRODUCTION Persistent sciatic artery (PSA) is a rare vascular anomaly associated with a higher rate of aneurysm formation or thromboembolic complications causing lower extremity ischemia. PRESENTATION Of Case A 15-year-old female patient with bilateral PSA presented with lower extremity ischemia. Considering the age and symptoms of the patient, we did not perform any intervention, but continued surveillance with duplex ultrasonography in case of the high incidence of aneurysmal formation or thromboembolic event. DISCUSSION Epidemiology, development, anatomical structure, diagnosis and treatments of PSAs are discussed. CONCLUSION PSAs, are prone to early atheromatous degeneration and aneurysm formation. Treatment of a PSA mainly dependent on the symptoms is either by surgical procedures or by endovascular interventions. PMID:22096762

Electroencephalographic, Heart Rate, and Galvanic Skin Response Assessment for an Advertising Perception Study: Application to Antismoking Public Service Announcements

PubMed Central

Cartocci, Giulia; Caratù, Myriam; Modica, Enrica; Maglione, Anton Giulio; Rossi, Dario; Cherubino, Patrizia; Babiloni, Fabio

2017-01-01

The evaluation of advertising, products, and packaging is traditionally performed through methods based on self-reports and focus groups, but these approaches often appear poorly accurate in scientific terms. Neuroscience is increasingly applied to the investigation of the neurophysiological bases of the perception of and reaction to commercial stimuli to support traditional marketing methods. In this context, a particular sector or marketing is represented by public service announcements (PSAs). The objective of this protocol is to apply electroencephalography (EEG) and autonomic signal analysis to study responses to selected antismoking PSAs. Two EEG indices were employed: the frontal alpha band EEG asymmetry (the Approach Withdrawal (AW) index) and the frontal theta (effort index). Furthermore, the autonomic Emotional Index (EI) was calculated, as derived from the Galvanic Skin Response (GSR) and Heart Rate (HR) signals. The present protocol describes a series of operational and computational steps required to properly estimate, through the aforementioned indices, the emotional and cerebral reaction of a group of subjects towards a selected number of antismoking PSAs. In particular, a campaign characterized by a symbolic communication style (classified as "awarded" on the basis of the prizes received by specialized committees) obtained the highest approach values, as estimated by the AW index. A spot and an image belonging to the same PSA campaign based on the "fear arousing appeal" and with a narrative/experiential communication style (classified as "effective" on the basis of the economical/health-related improvements promoted) reported the lowest and highest effort values, respectively. This is probably due to the complexity of the storytelling (spot) and to the immediateness of the image (a lady who underwent a tracheotomy). Finally, the same "effective" campaign showed the highest EI values, possibly because of the empathy induced by the testimonial and the explicitness of the message. PMID:28872117

Electroencephalographic, Heart Rate, and Galvanic Skin Response Assessment for an Advertising Perception Study: Application to Antismoking Public Service Announcements.

PubMed

Cartocci, Giulia; Caratù, Myriam; Modica, Enrica; Maglione, Anton Giulio; Rossi, Dario; Cherubino, Patrizia; Babiloni, Fabio

2017-08-28

The evaluation of advertising, products, and packaging is traditionally performed through methods based on self-reports and focus groups, but these approaches often appear poorly accurate in scientific terms. Neuroscience is increasingly applied to the investigation of the neurophysiological bases of the perception of and reaction to commercial stimuli to support traditional marketing methods. In this context, a particular sector or marketing is represented by public service announcements (PSAs). The objective of this protocol is to apply electroencephalography (EEG) and autonomic signal analysis to study responses to selected antismoking PSAs. Two EEG indices were employed: the frontal alpha band EEG asymmetry (the Approach Withdrawal (AW) index) and the frontal theta (effort index). Furthermore, the autonomic Emotional Index (EI) was calculated, as derived from the Galvanic Skin Response (GSR) and Heart Rate (HR) signals. The present protocol describes a series of operational and computational steps required to properly estimate, through the aforementioned indices, the emotional and cerebral reaction of a group of subjects towards a selected number of antismoking PSAs. In particular, a campaign characterized by a symbolic communication style (classified as "awarded" on the basis of the prizes received by specialized committees) obtained the highest approach values, as estimated by the AW index. A spot and an image belonging to the same PSA campaign based on the "fear arousing appeal" and with a narrative/experiential communication style (classified as "effective" on the basis of the economical/health-related improvements promoted) reported the lowest and highest effort values, respectively. This is probably due to the complexity of the storytelling (spot) and to the immediateness of the image (a lady who underwent a tracheotomy). Finally, the same "effective" campaign showed the highest EI values, possibly because of the empathy induced by the testimonial and the explicitness of the message.

One Size Does Not Fit All: Human Failure Event Decomposition and Task Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ronald Laurids Boring, PhD

2014-09-01

In the probabilistic safety assessments (PSAs) used in the nuclear industry, human failure events (HFEs) are determined as a subset of hardware failures, namely those hardware failures that could be triggered or exacerbated by human action or inaction. This approach is top-down, starting with hardware faults and deducing human contributions to those faults. Elsewhere, more traditionally human factors driven approaches would tend to look at opportunities for human errors first in a task analysis and then identify which of those errors is risk significant. The intersection of top-down and bottom-up approaches to defining HFEs has not been carefully studied. Ideally,more » both approaches should arrive at the same set of HFEs. This question remains central as human reliability analysis (HRA) methods are generalized to new domains like oil and gas. The HFEs used in nuclear PSAs tend to be top-down—defined as a subset of the PSA—whereas the HFEs used in petroleum quantitative risk assessments (QRAs) are more likely to be bottom-up—derived from a task analysis conducted by human factors experts. The marriage of these approaches is necessary in order to ensure that HRA methods developed for top-down HFEs are also sufficient for bottom-up applications. In this paper, I first review top-down and bottom-up approaches for defining HFEs and then present a seven-step guideline to ensure a task analysis completed as part of human error identification decomposes to a level suitable for use as HFEs. This guideline illustrates an effective way to bridge the bottom-up approach with top-down requirements.« less

An Examination of Adolescent Recall of Anti-Smoking Messages: Attitudes, Message Type, and Message Perceptions.

PubMed

Bigsby, Elisabeth; Monahan, Jennifer L; Ewoldsen, David R

2017-04-01

Delayed message recall may be influenced by currently held accessible attitudes, the nature of the message, and message perceptions (perception of bias and message elaboration). This study examined the potential of message perceptions to mediate the influence of valenced attitude accessibility and message type on unaided recall of anti-smoking Public Service Announcements (PSAs). In a field experiment, ninth grade students (N = 244) watched three PSAs and responded to items on laptop computers. Twelve weeks later, follow-up telephone surveys were conducted to assess unaided recall. Both valenced attitude accessibility and message type were associated with message perceptions. However, only perception of message bias partially mediated the relationship between message type and unaided recall.

Rehabilitation and Prosthetic Services

MedlinePlus

... VA Learning University (VALU) SimLearn Libraries (VALNET) VA Software Documentation Library (VDL) About VHA Learn about VHA Forms & ... & Sensory Aids Service (PSAS) Our Mission The mission of the Prosthetic & ...

How real-life health messages engage our brains: Shared processing of effective anti-alcohol videos

PubMed Central

Schmälzle, Ralf; Renner, Britta; Schupp, Harald T.

2017-01-01

Abstract Health communication via mass media is an important strategy when targeting risky drinking, but many questions remain about how health messages are processed and how they unfold their effects within receivers. Here we examine how the brains of young adults—a key target group for alcohol prevention—‘tune in’ to real-life health prevention messages about risky alcohol use. In a first study, a large sample of authentic public service announcements (PSAs) targeting the risks of alcohol was characterized using established measures of message effectiveness. In the main study, we used inter-subject correlation analysis of fMRI data to examine brain responses to more and less effective PSAs in a sample of young adults. We find that more effective messages command more similar responses within widespread brain regions, including the dorsomedial prefrontal cortex, insulae and precuneus. In previous research, these regions have been related to processing narratives, emotional stimuli, self-relevance and attention towards salient stimuli. The present study thus suggests that more effective health prevention messages have greater ‘neural reach’, i.e. they engage the brains of audience members’ more widely. This work outlines a promising strategy for assessing the effects of health communication at a neural level. PMID:28402568

How real-life health messages engage our brains: Shared processing of effective anti-alcohol videos.

PubMed

Imhof, Martin A; Schmälzle, Ralf; Renner, Britta; Schupp, Harald T

2017-07-01

Health communication via mass media is an important strategy when targeting risky drinking, but many questions remain about how health messages are processed and how they unfold their effects within receivers. Here we examine how the brains of young adults-a key target group for alcohol prevention-'tune in' to real-life health prevention messages about risky alcohol use. In a first study, a large sample of authentic public service announcements (PSAs) targeting the risks of alcohol was characterized using established measures of message effectiveness. In the main study, we used inter-subject correlation analysis of fMRI data to examine brain responses to more and less effective PSAs in a sample of young adults. We find that more effective messages command more similar responses within widespread brain regions, including the dorsomedial prefrontal cortex, insulae and precuneus. In previous research, these regions have been related to processing narratives, emotional stimuli, self-relevance and attention towards salient stimuli. The present study thus suggests that more effective health prevention messages have greater 'neural reach', i.e. they engage the brains of audience members' more widely. This work outlines a promising strategy for assessing the effects of health communication at a neural level. © The Author (2017). Published by Oxford University Press.

Predictive factors of 18F-choline PET/CT positivity in patients with prostate cancer recurrence after radiation therapy: is the impact of PSA nadir underestimated?

PubMed

Johnson, Alison C; Dugué, Audrey Emmanuelle; Silva, Marlon; Moise, Laura; Tillou, Xavier; Joly, Florence; Aide, Nicolas

2016-12-01

The objective of this study is to explore the impact of PSA nadirs on detection rates of prostate cancer (PCa) recurrence with 18 F-choline (CH) PET/CT after external beam radiation therapy (EBRT). In this retrospective study, data were collected from 54 patients with suspicion of PCa biochemical recurrence after EBRT (28 patients treated initially with EBRT and 26 as salvage therapy in the absence of PSA decrease after initial treatment), who underwent 18 F-CH PET/CT between 2010 and 2015. PSA nadir and trigger PSA were collected from patient files. Relative PSA was calculated by subtracting the nadir from the trigger PSA. Median PSA nadir was 0.31 (0.01-13.31) ng/mL, trigger PSA was 7.85 (0.47-111.60) ng/mL, and relative PSA was 6.05 (0.24-104.59) ng/mL. Overall, 40 (74%) PET/CT scans were positive: recurrence was local and/or regional in 29 patients, distant in 15 and combined both in four, with no association between PSA values and sites of recurrence. In univariate analysis, trigger (p = 0.015) and relative (p = 0.0005) PSA values and PSA velocity (p = 0.01) were significantly linked to positive PET/CT, but PSA nadir was not. In subgroup analysis, these significant differences were only found in the salvage EBRT group. Akaike Information Criterion multivariate model comparison found that relative PSA was a better predictor of positive PET/CT than trigger PSA (PSAt). 18 F-CH PET/CT detection rates increased with trigger and relative PSA: 0% (0/4 patients), 71% (5/7 patients), and 81% (35/43 patients) for PSAt <2 ng/mL, 2≤ PSAt ≤4 ng/mL, and PSAt >4 ng/mL, respectively, and 14% (1/7 patients), 50% (5/10 patients), and 92% (34/37 patients) when relative PSA was taken into account instead of trigger PSA, with seven (13%) patients changing subgroups. We found a high overall detection rate and an increase in detection rates proportional to trigger and relative PSAs. Although relative PSA, taking into account PSA nadir, was a better predictive factor of PET/CT positivity in univariate analysis, this was most noticeable for high PSAs. For low PSAs, trigger PSA remains most relevant. Larger series with intermediate PSA values need to be studied to fully apprehend nadir impact.

The Role of Motivational and Persuasive Message Factors in Changing Implicit Attitudes Toward Smoking

PubMed Central

Rydell, Robert J.; Sherman, Steven J.; Boucher, Kathryn L.; Macy, Jonathan T.

2012-01-01

The current work examined the extent to which nicotine level affects the receptiveness of cigarette smokers to a compelling (strong) or a specious (weak) antismoking, public service announcement (PSA). The combination of nicotine loading (i.e., having just smoked a cigarette) and a strong antismoking PSA led to significantly more negative implicit evaluations of cigarettes; however, explicit evaluations were not changed by nicotine level or PSA quality. Smokers’ implicit evaluations of cigarettes were affected only by compelling PSAs when they had recently smoked but not when they were nicotine deprived or when they viewed weak PSAs. Because implicit evaluations of cigarettes predict deliberate smoking-related decisions, it is important to understand which factors can render these implicit evaluations relatively more negative. PMID:23606782

An evaluation of a mass media campaign to encourage parents of adolescents to talk to their children about sex.

PubMed

DuRant, Robert H; Wolfson, Mark; LaFrance, Betty; Balkrishnan, Rajesh; Altman, David

2006-03-01

We evaluated a mass media campaign in North Carolina that used television (TV) public service announcements (PSAs), radio PSAs, and billboards to encourage parents of adolescents to talk to their children about sex. The primary message of the campaign was "Talk to your kids about sex. Everyone else is." Thirty-two of the 100 counties in North Carolina were chosen to evaluate the mass media campaign. Paid TV PSAs were aired in 22 of these counties, radio PSAs were aired in 21 counties, and billboards were displayed in 6 counties over a period of 9 months. The counties in our sample varied from no exposure to exposure to all 3 types of media. To assess the impact of the campaign, a sample of 1,132 parents of adolescents living in the 32 counties was administered a postexposure survey via a telephone interview. Questions about exposure to the media campaign were embedded among questions concerning media exposure to other health-related messages. The parent survey assessed the frequency the parents reported exposure to each type of media message, correct knowledge of the message, and multiple item scales that assessed how often they had talked to their child about various issues related to sex during the previous 6 months, intentions to talk to their child about these issues during the next month, and attitudes about discussing sexual issues with their child. In bivariate analyses the levels of parental exposure to the 3 types of media messages were associated with both having talked to their children and intentions to talk to their children about sex (p < .0001). When analyzed with multiple regression, female gender, minority ethnicity, frequency of seeing a billboard on teenage pregnancy, frequency of seeing a TV PSA about sex, and frequency of hearing a radio PSA about sex and teenage pregnancy accounted for 12.8% (p < .0001) of the variance in having talked to their child about sex. Female gender, minority ethnicity, and previously talking to their child about sex accounted for 9.9% of the variation in positive communication attitudes about sex. Positive communication attitudes, female parent, minority ethnicity, frequency of seeing a billboard about sex, frequency of seeing a TV PSA about sex, and frequency of hearing radio PSAs about sex accounted for 12.3% of the variation in parental intentions to talk to their child about sex during the next month. Exposure to each component of this mass media campaign was associated with parents recently having talked to their adolescent children about sex and intentions to talk to their children during the next month.

Partnership at Drugfree.org

MedlinePlus

... Local Alliance Access Community Education Resources Host a Film Screening View & Share PSAs Volunteer with Us Become ... Resources to Help Your Community Host a Community Film Screening How We’re Doing: 2016 Project Report ...

American College Health Association

MedlinePlus

... Health and Wellness Consulting Mental Health Symposium Patient Satisfaction Assessment Service Leadership Institute Healthy Campus 2020 Continuing ... and behaviors. Learn More >> PSAS The ACHA-Patient Satisfaction Assessment Service gauges patient satisfaction and provides insight ...

Sleep-related cognitive processes, arousal, and emotion dysregulation in insomnia disorder: the role of insomnia-specific rumination.

PubMed

Palagini, Laura; Moretto, Umberto; Dell'Osso, Liliana; Carney, Colleen

2017-02-01

Insomnia-specific rumination has presented in subjects with insomnia. Research has identified hyperarousal as a key factor, with both trait and state components. It has been shown that emotion dysregulation also plays a role in insomnia. Hence, the aim was to investigate how insomnia rumination is associated with both trait- and state-dependent arousal and emotion dysregulation in insomnia. Sixty-eight subjects with insomnia disorder (DSM-5) and 36 good sleepers were evaluated using: Insomnia Severity Index (ISI), Daytime Insomnia Symptom Response Scale (DISRS), Arousal Predisposition Scale (APS), Pre-sleep Arousal Scale (PSAS), and Difficulties in Emotion Regulation Scale (DERS). Univariate and multivariate regression analyses and mediation analyses were performed. Subjects with insomnia (F 41, mean age 50.2 ± 10) presented higher scores than good sleepers (F 22, mean age 49.7 ± 14) in all the scales (ISI, DISRS, APS, PSAS, DERS; p < 0.0001). Insomnia rumination was directly correlated with trait (APS, B = 0.22, p < 0.0001) pre-sleep state arousal (PSAS cognitive B = 0.22, p < 0.0001, PSAS somatic B = 0.24, p < 0.0001) and emotion dysregulation (B = 0.5, p = 0.03). It mediated the association between trait and pre-sleep state hyperarousal (Z = 3.3, p = 0.0008), the bidirectional association between cognitive and somatic arousal (p = 0.02), and the association between trait hyperarousal and emotion dysregulation (Z = 2.3, p = 0.04). In insomnia, specific rumination is related to both trait predisposition to arousal and to state-dependent arousal. It is also related to emotion dyregulation. Insomnia-specific ruminative response style may modulate the complex association between trait- and state-dependent arousal factors and arousal and emotion regulation in insomnia. In this framework, a broad range of cognitive processes may be considered when dealing with subjects with insomnia: the use of rumination-oriented psychological strategies could be important. Copyright © 2016 Elsevier B.V. All rights reserved.

Design and preparation of plant oil-based polymers and their applications

NASA Astrophysics Data System (ADS)

Ahn, Byung-Jun Kollbe

Renewable materials are desirable for many applications due to the finite fossil resources and environmental issues. Plant oil is one of the most promising renewable feedstocks. Plant oils and functionalized oleo-chemicals including functionalized soybean oils have become attractive sustainable chemicals for industrial applications. Especially, epoxidized oleo-chemicals such as epoxidized soybean oil (ESO) are one of the most well-known readily available inexpensive functionalized plant oils. In this study, novel polymers and nanocomposites for sustainable materials applications were designed and prepared via ring-opening of epoxide in plant oils, and their chemical and physical properties were characterized. The novel transparent elastomers derived from functionalized plant oils have a great potential as flexible electronic and biological applications with their inherent low toxicity. Especially, their rheological properties showed a potential for pressure sensitive adhesives (PSAs). The dominant thermal stability and transparency were obtained via green processing: one pot, single step, fast reactions in moderate conditions, or solvent-free UV curing conditions. These oleo-based elastomers presented excellent end-use properties for PSAs application comparable to commercial PSA tapes. Based on the principal chemical studies, the roles of the each component have been identified: polymer derived from the ring-opening of epoxides as an elastomer, and dihydroxylated triglycerides as a tackifier. Their interaction was also elucidated with an element label analysis. The mechanical and rheological properties of the oleo-polymer as PSAs were able to be improved with a rosin ester tackifier. In addition, biogreases and bio-thermoplastics were developed via the environmentally benign process, which will contribute to further application on the production of new bio-based materials. Further, this study essays a novel acid functionalized iron/iron oxide nanoparticles catalyst with excellent product yields for epoxide ring opening of oleochemicals for a greener synthetic method of biopolyols, and excellent environmental benefits with life cycle assessment of syntheses. Those functionalized iron/iron oxide core shell nanoparticles catalysts has great potential for biomedical engineering process with the highest magnetization of Fe(0) core among all metals.

78 FR 23970 - Reports, Forms, and Record Keeping Requirements

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-23

... information for which the agency is seeking approval from OMB: Title: Buzzed Driving is Drunk Driving PSA... impact that the public service announcements (PSAs) from this campaign may have upon attitudes and...

Winter Weather Frequently Asked Questions

MedlinePlus

... Hot Weather Tips Warning Signs and Symptoms FAQs Social Media How to Stay Cool Missouri Cooling Centers Extreme ... PSAs for Disasters Resources for Emergency Health Professionals Social Media Health and Safety Concerns for All Disasters Animals ...

Winter Weather: Outdoor Safety

MedlinePlus

... Hot Weather Tips Warning Signs and Symptoms FAQs Social Media How to Stay Cool Missouri Cooling Centers Extreme ... PSAs for Disasters Resources for Emergency Health Professionals Social Media Health and Safety Concerns for All Disasters Animals ...

Buying & Using Medicine Safely

MedlinePlus

... Generic Drugs - Patient Education Resources Patient and Prescriber materials: Videos, PSAs, factsheets and more. Spotlight Drugs@FDA Index to Drug-Specific Information Protecting Yourself Safe Disposal of Medicines Generic Medicines – safe, effective and ...

Health Risk Assessment for Inhalation Exposure to Methyl Tertiary Butyl Ether at Petrol Stations in Southern China

PubMed Central

Hu, Dalin; Yang, Jianping; Liu, Yungang; Zhang, Wenjuan; Peng, Xiaowu; Wei, Qinzhi; Yuan, Jianhui; Zhu, Zhiliang

2016-01-01

Methyl tertiary butyl ether (MTBE), a well known gasoline additive, is used in China nationwide to enhance the octane number of gasoline and reduce harmful exhaust emissions, yet  little is known regarding the potential health risk associated with occupational exposure to MTBE in petrol stations. In this study, 97 petrol station attendants (PSAs) in southern China were recruited for an assessment of the health risk associated with inhalation exposure to MTBE. The personal exposure levels of MTBE were analyzed by Head Space Solid Phase Microextraction GC/MS, and the demographic characteristics of the PSAs were investigated. Cancer and non-cancer risks were calculated with the methods recommended by the United States Environmental Protection Agency. The results showed that the exposure levels of MTBE in operating workers were much higher than among support staff (p < 0.01) and both were lower than 50 ppm (an occupational threshold limit value). The calculated cancer risks (CRs) at the investigated petrol stations was 0.170 to 0.240 per 106 for operating workers, and 0.026 to 0.049 per 106 for support staff, which are below the typical target range for risk management of 1 × 10−6 to 1 × 10−4; The hazard quotients (HQs) for all subjects were <1. In conclusion, our study indicates that the MTBE exposure of PSAs in southern China is in a low range which does not seem to be a significant health risk. PMID:26861375

Health Risk Assessment for Inhalation Exposure to Methyl Tertiary Butyl Ether at Petrol Stations in Southern China.

PubMed

Hu, Dalin; Yang, Jianping; Liu, Yungang; Zhang, Wenjuan; Peng, Xiaowu; Wei, Qinzhi; Yuan, Jianhui; Zhu, Zhiliang

2016-02-06

Methyl tertiary butyl ether (MTBE), a well known gasoline additive, is used in China nationwide to enhance the octane number of gasoline and reduce harmful exhaust emissions, yet little is known regarding the potential health risk associated with occupational exposure to MTBE in petrol stations. In this study, 97 petrol station attendants (PSAs) in southern China were recruited for an assessment of the health risk associated with inhalation exposure to MTBE. The personal exposure levels of MTBE were analyzed by Head Space Solid Phase Microextraction GC/MS, and the demographic characteristics of the PSAs were investigated. Cancer and non-cancer risks were calculated with the methods recommended by the United States Environmental Protection Agency. The results showed that the exposure levels of MTBE in operating workers were much higher than among support staff (p < 0.01) and both were lower than 50 ppm (an occupational threshold limit value). The calculated cancer risks (CRs) at the investigated petrol stations was 0.170 to 0.240 per 10⁶ for operating workers, and 0.026 to 0.049 per 10⁶ for support staff, which are below the typical target range for risk management of 1 × 10(-6) to 1 × 10(-4); The hazard quotients (HQs) for all subjects were <1. In conclusion, our study indicates that the MTBE exposure of PSAs in southern China is in a low range which does not seem to be a significant health risk.

The GEOS Ozone Data Assimilation System: Specification of Error Statistics

NASA Technical Reports Server (NTRS)

Stajner, Ivanka; Riishojgaard, Lars Peter; Rood, Richard B.

2000-01-01

A global three-dimensional ozone data assimilation system has been developed at the Data Assimilation Office of the NASA/Goddard Space Flight Center. The Total Ozone Mapping Spectrometer (TOMS) total ozone and the Solar Backscatter Ultraviolet (SBUV) or (SBUV/2) partial ozone profile observations are assimilated. The assimilation, into an off-line ozone transport model, is done using the global Physical-space Statistical Analysis Scheme (PSAS). This system became operational in December 1999. A detailed description of the statistical analysis scheme, and in particular, the forecast and observation error covariance models is given. A new global anisotropic horizontal forecast error correlation model accounts for a varying distribution of observations with latitude. Correlations are largest in the zonal direction in the tropics where data is sparse. Forecast error variance model is proportional to the ozone field. The forecast error covariance parameters were determined by maximum likelihood estimation. The error covariance models are validated using x squared statistics. The analyzed ozone fields in the winter 1992 are validated against independent observations from ozone sondes and HALOE. There is better than 10% agreement between mean Halogen Occultation Experiment (HALOE) and analysis fields between 70 and 0.2 hPa. The global root-mean-square (RMS) difference between TOMS observed and forecast values is less than 4%. The global RMS difference between SBUV observed and analyzed ozone between 50 and 3 hPa is less than 15%.

The effect of message frame in anti-smoking public service announcements on cognitive response and attitude toward smoking.

PubMed

Shen, Lijiang

2010-01-01

This study investigated whether and how message frames in anti-smoking public service announcements (PSAs) affect individuals' cognition and attitude toward smoking. Individuals in a sample of 315 participants were randomly assigned to one of three experimental framing conditions: (a) health consequence, (b) secondhand smoke, and (c) industry manipulation. Each participant viewed four PSAs in a random order within a particular message frame. The study found strong evidence for the application effect in framing. The accessibility effect in framing was found to be conditional on message frame. Individuals' cognition on health consequence of smoking and on industry manipulation predicted their attitude toward smoking, but not cognition on secondhand smoke. The three frames also led to different patterns of affective responses that can be a basis for persuasion. Implications for message framing effect and anti-smoking campaigns were discussed.

HIV Prevention Messages Targeting Young Latino Immigrant MSM.

PubMed

Solorio, Rosa; Norton-Shelpuk, Pamela; Forehand, Mark; Martinez, Marcos; Aguirre, Joel

2014-01-01

Young Latino immigrant men who have sex with men (MSM) are at risk for HIV and for delayed diagnosis. A need exists to raise awareness about HIV prevention in this population, including the benefits of timely HIV testing. This project was developed through collaboration between University of WA researchers and Entre Hermanos, a community-based organization serving Latinos. Building from a community-based participatory research approach, the researchers developed a campaign that was executed by Activate Brands, based in Denver, Colorado. The authors (a) describe the development of HIV prevention messages through the integration of previously collected formative data; (b) describe the process of translating these messages into PSAs, including the application of a marketing strategy; (c) describe testing the PSAs within the Latino MSM community; and (c) determine a set of important factors to consider when developing HIV prevention messages for young Latino MSM who do not identify as gay.

A Measure of Perceived Argument Strength: Reliability and Validity

PubMed Central

Zhao, Xiaoquan; Strasser, Andrew; Cappella, Joseph N.; Lerman, Caryn; Fishbein, Martin

2014-01-01

Studies of the content of persuasive messages in which the central arguments of the message are scrutinized have traditionally relied on the technique of thought-listing to assess argument strength. Although the validity of the thought-listing procedure is well documented, its utility can be limited in situations involving non-adult populations and sensitive topics. In this paper we present a self-reported scale that can be used to assess perceived argument strength in contexts where thought-listing may be less appropriate. This scale taps into perceived argument strength from multiple points of view, including but also extending beyond the potential of the argument to elicit positive and negative thoughts. Reliability and validity of this scale were assessed in health communication contexts involving anti-drug PSAs directed at adolescents and anti-smoking PSAs targeting adults. Evidence of convergence between this scale and the thought-listing technique was also obtained using the classical comprehensive exam arguments. PMID:25568663

Personal involvement of young people in HIV prevention campaign messages: the role of message format, culture, and gender.

PubMed

Geary, Cynthia Waszak; Burke, Holly M; Johnson, Laura; Liku, Jennifer; Castelnau, Laure; Neupane, Shailes; Niang, Cheikh

2008-04-01

To examine young people's reactions to and understanding of HIV prevention messages developed for MTV's global HIV prevention campaign Staying Alive, videotaped campaign materials were shown to focus group discussion (FGD) participants living in urban areas of Brazil, Kenya, Nepal, and Senegal. Responses related to "personal involvement" with the message were identified in the data from these FGDs and were examined in relationship to the emerging message themes, the message format (public service announcements [PSAs] vs. documentary), cultural context (site), and participant gender. Across groups, greater personal involvement (measured by personal connections, emotional reactions, and lessons learned) was found in responses about the documentary format compared to the PSA format. Exceptions were found for specific PSAs that were considered more relevant within specific gender or cultural contexts. Implications of findings for global campaigns were considered.

HIV Prevention Messages Targeting Young Latino Immigrant MSM

PubMed Central

Solorio, Rosa; Forehand, Mark; Aguirre, Joel

2014-01-01

Young Latino immigrant men who have sex with men (MSM) are at risk for HIV and for delayed diagnosis. A need exists to raise awareness about HIV prevention in this population, including the benefits of timely HIV testing. This project was developed through collaboration between University of WA researchers and Entre Hermanos, a community-based organization serving Latinos. Building from a community-based participatory research approach, the researchers developed a campaign that was executed by Activate Brands, based in Denver, Colorado. The authors (a) describe the development of HIV prevention messages through the integration of previously collected formative data; (b) describe the process of translating these messages into PSAs, including the application of a marketing strategy; (c) describe testing the PSAs within the Latino MSM community; and (c) determine a set of important factors to consider when developing HIV prevention messages for young Latino MSM who do not identify as gay. PMID:24864201

Do perceptions of effective distractive driving public service announcements differ between adults and teens?

PubMed

Solomon, Barbara J; Hendry, Phyllis; Kalynych, Colleen; Taylor, Pam; Tepas, Joseph J

2010-10-01

Motor vehicle crashes remain the leading cause of death and disability in teenagers. Graduated licensing laws, enforcement of a legal drinking age of 21 years, zero tolerance, and mandatory restraints have been successful in reducing crashes and fatalities. Media safety campaigns have been less successful. This study was designed to analyze whether perceived effectiveness of public service announcements (PSAs) differed between teens and adults. We hypothesized that adult-derived intent differs from teen perception. High-school students attending an annual municipal student safety exposition were asked to rank order six PSAs that were previously judged by an almost all adult committee. Additionally, students were asked to rate the PSAs on an agreement Likert scale assessing interest, understandability, and believability and to indicate potential effect on driving behavior. Students further graded their agreement with 10 top-published driving distracters and were asked to list additional perceived driving distracters. Of the 330 surveys collected, 201 students aged 14 years to 19 years selected at least one choice and 181 ranked-ordered >1 PSA. The PSA #3 selected by the original adult judges was ranked second (33%) by teens with PSA #1 in first place (34%). PSA 1 was not considered as effective by the adult judges. Student age, race, grade, or gender did not produce statistically significant differences. A cohort of 186 teens responded to nationally noted driving distracters with >86% in agreement. Eating and applying cosmetics were additional distracters noted by students completing the survey. Preventative media messages should include teen stakeholder review. The components of effective adolescent safety messages continue to require further study.

What You Need to Know When the Power Goes Out Unexpectedly

MedlinePlus

... Hot Weather Tips Warning Signs and Symptoms FAQs Social Media How to Stay Cool Missouri Cooling Centers Extreme ... PSAs for Disasters Resources for Emergency Health Professionals Social Media Health and Safety Concerns for All Disasters Animals ...

Letter from Thomas J Graves on Concerns about National Public Awareness Campaign on Childhood Lead Poisoning

EPA Pesticide Factsheets

Request for correction of information by EPA withdrawal from sponsorship and participation in the print and video depictions used in the childhood lead poisoning PSAs are misleading and misrepresent the paint industry

Role of pressure-sensitive adhesives in transdermal drug delivery systems.

PubMed

Lobo, Shabbir; Sachdeva, Sameer; Goswami, Tarun

2016-01-01

Transdermal drug delivery systems (TDDS) are employed for the delivery of drugs across skin into the systemic circulation. Pressure-sensitive adhesive (PSA) is one of the most critical components used in a TDDS. The primary function of PSA is to help in adhesion of patch to skin, but more importantly it acts as a matrix for the drug and other excipients. Hence, apart from adhesion of the patch, PSA also affects other critical quality attributes of the TDDS such as drug delivery, flux through skin and physical and chemical stability of the finished product. This review article provides a summary of the adhesives used in various types of TDDS. In particular, this review will cover the design types of TDDS, categories of PSAs and their evaluation and regulatory aspects.

The Computational Complexity, Parallel Scalability, and Performance of Atmospheric Data Assimilation Algorithms

NASA Technical Reports Server (NTRS)

Lyster, Peter M.; Guo, J.; Clune, T.; Larson, J. W.; Atlas, Robert (Technical Monitor)

2001-01-01

The computational complexity of algorithms for Four Dimensional Data Assimilation (4DDA) at NASA's Data Assimilation Office (DAO) is discussed. In 4DDA, observations are assimilated with the output of a dynamical model to generate best-estimates of the states of the system. It is thus a mapping problem, whereby scattered observations are converted into regular accurate maps of wind, temperature, moisture and other variables. The DAO is developing and using 4DDA algorithms that provide these datasets, or analyses, in support of Earth System Science research. Two large-scale algorithms are discussed. The first approach, the Goddard Earth Observing System Data Assimilation System (GEOS DAS), uses an atmospheric general circulation model (GCM) and an observation-space based analysis system, the Physical-space Statistical Analysis System (PSAS). GEOS DAS is very similar to global meteorological weather forecasting data assimilation systems, but is used at NASA for climate research. Systems of this size typically run at between 1 and 20 gigaflop/s. The second approach, the Kalman filter, uses a more consistent algorithm to determine the forecast error covariance matrix than does GEOS DAS. For atmospheric assimilation, the gridded dynamical fields typically have More than 10(exp 6) variables, therefore the full error covariance matrix may be in excess of a teraword. For the Kalman filter this problem can easily scale to petaflop/s proportions. We discuss the computational complexity of GEOS DAS and our implementation of the Kalman filter. We also discuss and quantify some of the technical issues and limitations in developing efficient, in terms of wall clock time, and scalable parallel implementations of the algorithms.

Tailored community cancer education programs: Pawsox and prostates.

PubMed

Glicksman, Arvin S; Meyer, Andrea; Dipiero, Maureen

2010-06-01

To assess the prostate cancer screening practices in Rhode Island, we designed a questionnaire which was sent to 150 primary care physicians. A population-based survey was distributed to 194 men over 40 asking about screening history and risk factors. Eighty-five percent of primary care physicians reported performing annual prostate-specific antigen tests (PSAs) and digital rectal exams, 63% recognized family history as a risk factor, and 14% identified African Americans as a high-risk population. The survey found that 48% of men recognized family history as a risk factor and 6% understood that African Americans were at high risk. Each year, 200 men, primarily SED, are invited to a PawSox baseball game where physicians provide information on prostate cancer risk, treatment options, and outcomes. Free PSAs are provided. The questionnaire and survey demonstrate a need for more public education regarding prostate cancer in high-risk populations. Tailored community-based interventions, such as the Pawsox & Prostate program, can be effective professional and public education strategies to increase screening in high-risk populations.

Waterborne polyurethane-acrylic hybrid nanoparticles by miniemulsion polymerization: applications in pressure-sensitive adhesives.

PubMed

Lopez, Aitziber; Degrandi-Contraires, Elise; Canetta, Elisabetta; Creton, Costantino; Keddie, Joseph L; Asua, José M

2011-04-05

Waterborne polyurethane-acrylic hybrid nanoparticles for application as pressure-sensitive adhesives (PSAs) were prepared by one-step miniemulsion polymerization. The addition of polyurethane to a standard waterborne acrylic formulation results in a large increase in the cohesive strength and hence a much higher shear holding time (greater than seven weeks at room temperature), which is a very desirable characteristic for PSAs. However, with the increase in cohesion, there is a decrease in the relative viscous component, and hence there is a decrease in the tack energy. The presence of a small concentration of methyl methacrylate (MMA) in the acrylic copolymer led to phase separation within the particles and created a hemispherical morphology. The tack energy was particularly low in the hybrid containing MMA because of the effects of lower energy dissipation and greater cross-linking. These results highlight the great sensitivity of the viscoelastic and adhesive properties to the details of the polymer network architecture and hence to the precise composition and synthesis conditions.

Predictors of Learning from Public Service Announcements.

ERIC Educational Resources Information Center

Sun, Hsiu-hui

A study focused on predictors of people's learning from public service announcements (PSAs) seen on television. Telephone interviews were conducted with 480 adults randomly selected from residents in Dane County, Wisconsin, in October 1987. Typical demographic information was obtained: sex, age, income, occupation and education. Commercial slogans…

Controlling adhesive behavior during recycling

Treesearch

Carl Houtman; Karen Scallon; Jihui Guo; XinPing Wang; Steve Severtson; Mark Kroll; Mike Nowak

2004-01-01

Adhesives can be formulated to facilitate their removal by typical paper recycling unit operations. The investigations described in this paper are focused on determining fundamental properties that control particle size during pulping. While pressure-sensitive adhesives (PSAs) with high elastic moduli tend to survive pulping with larger particles, facestock and...

Humor as a Presentational Device in Broadcast Public Service Announcements.

ERIC Educational Resources Information Center

Swanson, D. J.

On a daily basis, American television and radio audiences are subjected to a stream of broadcast Public Service Announcements (PSAs), each promoting "some kind of social or economic action deemed beneficial" (Stridsberg, 1977). Often, these announcements employ humor as a presentational device to help stimulate the behavioral change…

Youth Gambling Prevention: Can Public Service Announcements Featuring Celebrity Spokespersons Be Effective?

ERIC Educational Resources Information Center

Shead, N. Will; Walsh, Kelly; Taylor, Amy; Derevensky, Jeffrey L.; Gupta, Rina

2011-01-01

Children and adolescents are at increased risk of developing gambling problems compared to adults. A review of successful prevention campaigns targeting drinking and driving, smoking, unprotected sex, and drug use suggests that public service announcements (PSAs) featuring celebrity spokespersons have strong potential for raising awareness of the…

EEG analysis of the brain activity during the observation of commercial, political, or public service announcements.

PubMed

Vecchiato, Giovanni; Astolfi, Laura; Tabarrini, Alessandro; Salinari, Serenella; Mattia, Donatella; Cincotti, Febo; Bianchi, Luigi; Sorrentino, Domenica; Aloise, Fabio; Soranzo, Ramon; Babiloni, Fabio

2010-01-01

The use of modern brain imaging techniques could be useful to understand what brain areas are involved in the observation of video clips related to commercial advertising, as well as for the support of political campaigns, and also the areas of Public Service Announcements (PSAs). In this paper we describe the capability of tracking brain activity during the observation of commercials, political spots, and PSAs with advanced high-resolution EEG statistical techniques in time and frequency domains in a group of normal subjects. We analyzed the statistically significant cortical spectral power activity in different frequency bands during the observation of a commercial video clip related to the use of a beer in a group of 13 normal subjects. In addition, a TV speech of the Prime Minister of Italy was analyzed in two groups of swing and "supporter" voters. Results suggested that the cortical activity during the observation of commercial spots could vary consistently across the spot. This fact suggest the possibility to remove the parts of the spot that are not particularly attractive by using those cerebral indexes. The cortical activity during the observation of the political speech indicated a major cortical activity in the supporters group when compared to the swing voters. In this case, it is possible to conclude that the communication proposed has failed to raise attention or interest on swing voters. In conclusions, high-resolution EEG statistical techniques have been proved to able to generate useful insights about the particular fruition of TV messages, related to both commercial as well as political fields.

EEG Analysis of the Brain Activity during the Observation of Commercial, Political, or Public Service Announcements

PubMed Central

Vecchiato, Giovanni; Astolfi, Laura; Tabarrini, Alessandro; Salinari, Serenella; Mattia, Donatella; Cincotti, Febo; Bianchi, Luigi; Sorrentino, Domenica; Aloise, Fabio; Soranzo, Ramon; Babiloni, Fabio

2010-01-01

The use of modern brain imaging techniques could be useful to understand what brain areas are involved in the observation of video clips related to commercial advertising, as well as for the support of political campaigns, and also the areas of Public Service Announcements (PSAs). In this paper we describe the capability of tracking brain activity during the observation of commercials, political spots, and PSAs with advanced high-resolution EEG statistical techniques in time and frequency domains in a group of normal subjects. We analyzed the statistically significant cortical spectral power activity in different frequency bands during the observation of a commercial video clip related to the use of a beer in a group of 13 normal subjects. In addition, a TV speech of the Prime Minister of Italy was analyzed in two groups of swing and “supporter” voters. Results suggested that the cortical activity during the observation of commercial spots could vary consistently across the spot. This fact suggest the possibility to remove the parts of the spot that are not particularly attractive by using those cerebral indexes. The cortical activity during the observation of the political speech indicated a major cortical activity in the supporters group when compared to the swing voters. In this case, it is possible to conclude that the communication proposed has failed to raise attention or interest on swing voters. In conclusions, high-resolution EEG statistical techniques have been proved to able to generate useful insights about the particular fruition of TV messages, related to both commercial as well as political fields. PMID:20069055

A Global Data Assimilation System for Atmospheric Aerosol

NASA Technical Reports Server (NTRS)

daSilva, Arlindo

1999-01-01

We will give an overview of an aerosol data assimilation system which combines advances in remote sensing of atmospheric aerosols, aerosol modeling and data assimilation methodology to produce high spatial and temporal resolution 3D aerosol fields. Initially, the Goddard Aerosol Assimilation System (GAAS) will assimilate TOMS, AVHRR and AERONET observations; later we will include MODIS and MISR. This data assimilation capability will allows us to integrate complementing aerosol observations from these platforms, enabling the development of an assimilated aerosol climatology as well as a global aerosol forecasting system in support of field campaigns. Furthermore, this system provides an interactive retrieval framework for each aerosol observing satellites, in particular TOMS and AVHRR. The Goddard Aerosol Assimilation System (GAAS) takes advantage of recent advances in constituent data assimilation at DAO, including flow dependent parameterizations of error covariances and the proper consideration of model bias. For its prognostic transport model, GAAS will utilize the Goddard Ozone, Chemistry, Aerosol, Radiation and Transport (GOCART) model developed at NASA/GSFC Codes 916 and 910.3. GOCART includes the Lin-Rood flux-form, semi-Langrangian transport model with parameterized aerosol chemistry and physical processes for absorbing (dust and black carbon) and non-absorbing aerosols (sulfate and organic carbon). Observations and model fields are combined using a constituent version of DAO's Physical-space Statistical Analysis System (PSAS), including its adaptive quality control system. In this talk we describe the main components of this assimilation system and present preliminary results obtained by assimilating TOMS data.

Defense.gov Special Report: Combined Federal Campaign

Science.gov Websites

250 words) and high resolution pictures (minimum 1MB) of your agencies campaign by emailing Ms Department of Defense Dependent Schools (DoDDS) High School Public Service Announcement (PSA) Contest . Contest judges recognized five high schools. View all winning PSAs below: 1st Place, Kadena High School

Surface Enrichment by Conventional and Polymerizable Sulfated Nonylphenol Ethoxylate Emulsifiers in Water-Based Pressure-Sensitive Adhesive

Treesearch

Jilin Zhang; Yuxi Zhao; Matthew R. Dubay; Steven J. Severtson; Larry E. Gwin; Carl J. Houtman

2013-01-01

Comparisons of properties are made for pressure-sensitive adhesives (PSAs) generated via emulsion polymerization using both conventional and reactive emulsifiers. The emulsifiers are ammonium salts of sulfated nonylphenol ethoxylates with similar chemical structures and hydrophilic−lipophilic balances. The polymerizable surfactant possesses a reactive double...

Talking about AIDS in Hong Kong: Cultural Models in Public Health Discourse.

ERIC Educational Resources Information Center

Jones, Rodney H.

A study explored the issues of cultural identity and interaction in public health discourse concerning Acquired Immune Deficiency Syndrome (AIDS) in Hong Kong's multilingual, multicultural social context. Twenty public service announcements (PSAs) concerning AIDS awareness televised in both English and Cantonese in Hong Kong from 1987 to 1994 were…

47 CFR 101.56 - Partitioned service areas (PSAs) and disaggregated spectrum.

Code of Federal Regulations, 2013 CFR

2013-10-01

... area will be treated as a separate protected service area. (d)(1) When any area within an EA becomes a...) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Applications and Licenses License Transfers.... (a)(1) The holder of an EA authorization to provide service pursuant to the competitive bidding...

47 CFR 101.56 - Partitioned service areas (PSAs) and disaggregated spectrum.

Code of Federal Regulations, 2014 CFR

2014-10-01

... area will be treated as a separate protected service area. (d)(1) When any area within an EA becomes a...) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Applications and Licenses License Transfers.... (a)(1) The holder of an EA authorization to provide service pursuant to the competitive bidding...

47 CFR 101.56 - Partitioned service areas (PSAs) and disaggregated spectrum.

Code of Federal Regulations, 2011 CFR

2011-10-01

... area will be treated as a separate protected service area. (d)(1) When any area within an EA becomes a...) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Applications and Licenses License Transfers.... (a)(1) The holder of an EA authorization to provide service pursuant to the competitive bidding...

47 CFR 101.56 - Partitioned service areas (PSAs) and disaggregated spectrum.

Code of Federal Regulations, 2012 CFR

2012-10-01

... area will be treated as a separate protected service area. (d)(1) When any area within an EA becomes a...) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Applications and Licenses License Transfers.... (a)(1) The holder of an EA authorization to provide service pursuant to the competitive bidding...

Associations Between Message Features and Subjective Evaluations of the Sensation Value of Antidrug Public Service Announcements.

ERIC Educational Resources Information Center

Morgan, Susan E.; Palmgreen, Philip; Stephenson, Michael T.; Hoyle, Rick H.; Lorch, Elizabeth P.

2003-01-01

Identifies message design features that show the greatest promise for developing message high in sensation value for anti-drug campaigns and other interventions aimed at sensation-seeking risky behaviors. Investigates certain features of drug prevention Public Service Announcements (PSAs) associated with viewers' subjective responses to them.…

Mitigating Psychological Reactance: The Role of Message-Induced Empathy in Persuasion

ERIC Educational Resources Information Center

Shen, Lijiang

2010-01-01

This article examines the role of message-induced state empathy in persuasion. Message-induced empathy is conceptualized as a perception-action process that consists of affective, cognitive, and associative components. Twenty professionally produced public service announcements (PSAs) were used as stimuli messages in a 2 (high vs. low empathy) x 2…

Influence of Self-Affirmation on Responses to Gain- versus Loss-Framed Antismoking Messages

ERIC Educational Resources Information Center

Zhao, Xiaoquan; Nan, Xiaoli

2010-01-01

Self-affirmation has been shown to reduce biased processing of threatening health messages. In this study, the impact of self-affirmation on college smokers' reactions to gain- versus loss-framed antismoking public service announcements (PSAs) was examined. A consistent pattern of interaction was observed wherein self-affirmation produced more…

Effects of a Televised Two-City Safer Sex Mass Media Campaign Targeting High-Sensation-Seeking and Impulsive-Decision-Making Young Adults

PubMed Central

Zimmerman, Rick S.; Palmgreen, Philip M.; Noar, Seth M.; Lustria, Mia Liza A.; Lu, Hung-Yi; Horosewski, Mary Lee

2015-01-01

This study evaluates the ability of a safer sex televised public service announcement (PSA) campaign to increase safer sexual behavior among at-risk young adults. Independent, monthly random samples of 100 individuals were surveyed in each city for 21 months as part of an interrupted-time-series design with a control community. The 3-month high-audience-saturation campaign took place in Lexington, KY, with Knoxville, TN, as a comparison city. Messages were especially designed and selected for the target audience (those above the median on a composite sensation-seeking/impulsive-decision-making scale). Data indicate high campaign exposure among the target audience, with 85%–96% reporting viewing one or more PSAs. Analyses indicate significant 5-month increases in condom use, condom-use self-efficacy, and behavioral intentions among the target group in the campaign city with no changes in the comparison city. The results suggest that a carefully targeted, intensive mass media campaign using televised PSAs can change safer sexual behaviors. PMID:17602097

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gibson-Grant, Amy

Postwave tracking study for the Energy Efficiency Adult Campaign This study serves as measure of key metrics among the campaign’s target audience, homeowners age 25+. Key measures include: Awareness of messages relating to the broad issue; Recognition of the PSAs; Relevant attitudes, including interest, ease of taking energy efficient steps, and likelihood to act; Relevant knowledge, including knowledge of light bulb alternatives and energy efficient options; and Relevant behaviors, including specific energy-saving behaviors mentioned within the PSAs. Wave 1: May 27 – June 7, 2011 Wave 2: May 29 – June 8, 2012 Wave 3: May 29 – June 19,more » 2014 General market sample of adults 25+ who own their homes W1 sample: n = 704; W2: n=701; W3: n=806 Online Survey Panel Methodology Study was fielded by Lightspeed Research among their survey panel. Sample is US Census representative of US homeowners by race/ethnicity, income, age, region, and family status. At least 30% of respondents were required to have not updated major appliances in their home in the past 5 years (dishwasher, stove, refrigerator, washer, or dryer).« less

Effects of cognitive behavioral therapy in patients with depressive disorder and comorbid insomnia: A propensity score-matched outcome study.

PubMed

Hsu, Hui-Min; Chou, Kuei-Ru; Lin, Kuan-Chia; Chen, Kuan-Yu; Su, Shu-Fang; Chung, Min-Huey

2015-10-01

We evaluated the effects of cognitive behavioral therapy for insomnia (CBT-I) in inpatients with a diagnosis of depression and comorbid insomnia. This study used a prospective, parallel-group design. The experimental group received CBT-I for no more than 90 min once weekly for 6 weeks and the control group only have health education manuals for insomnia. The following questionnaires were administered at baseline: the Hamilton Rating Scale for Depression (HAM-D), Dysfunctional Beliefs and Attitudes about Sleep (DBAS), Presleep Arousal Scale (PSAS), Sleep Hygiene Practice (SHP), and Pittsburgh Sleep Quality Index. The questionnaires were readministered after the completion of the 6-wk CBT-I intervention and 1 month following the completion of CBT-I, to determine the effects of the CBT-I intervention over time. The analysis of Generalized Estimation Equations was identified the difference between the experimental group and the control group by controlling for the variables in BZD dose and propensity score of gender, age, and the scores for the DBAS-16, PSAS, SHPS, and HAM-D. Consequently, the significant difference in the PSQI scores was observed at the 1-month follow-up assessment however, no significant intergroup difference in the PSQI scores was found at the completion of the CBT-I intervention between two groups. As a conclusion, we found that overall sleep quality significantly improved in patients who received CBT-I after we controlled for the BZD dose and propensity score, which suggests that CBT-I may represent a useful clinical strategy for improving sleep quality in patients with depression and comorbid insomnia. Copyright © 2015 Elsevier Ltd. All rights reserved.

Climate Data Assimilation on a Massively Parallel Supercomputer

NASA Technical Reports Server (NTRS)

Ding, Hong Q.; Ferraro, Robert D.

1996-01-01

We have designed and implemented a set of highly efficient and highly scalable algorithms for an unstructured computational package, the PSAS data assimilation package, as demonstrated by detailed performance analysis of systematic runs on up to 512-nodes of an Intel Paragon. The preconditioned Conjugate Gradient solver achieves a sustained 18 Gflops performance. Consequently, we achieve an unprecedented 100-fold reduction in time to solution on the Intel Paragon over a single head of a Cray C90. This not only exceeds the daily performance requirement of the Data Assimilation Office at NASA's Goddard Space Flight Center, but also makes it possible to explore much larger and challenging data assimilation problems which are unthinkable on a traditional computer platform such as the Cray C90.

Network Commercials Promote Legal Drugs: Outnumber Anti-Drug PSA's 45-to-1.

ERIC Educational Resources Information Center

Fedler, Fred; And Others

1994-01-01

During the week of September 16-20, 1990, commercials promoting drugs and alcohol outnumbered the networks' news stories, documentaries, and public service announcements (PSAs) about illegal drugs by a ratio of almost 39 to 1. Considering the commercials alone, promotion of drugs and alcohol outnumbered the antidrug promotions by a ratio of almost…

Compatibility of pressure sensitive adhesives with recycling unit operations

Treesearch

David Bormett; Carl Houtman; Said Abubakr; Joseph Peng

1999-01-01

Removal of pressure sensitive adhesives (PSAs) from recovered paper is a major problem facing the paper recycling industry. As a result of a United States Postal Service (USPS) initiative, which currently purchases about 12% of domestic PSA production, a team was formed consisting of representatives from the USPS, the Forest Products Laboratory, Springborn Testing and...

In Their Own Words: Coteaching Project at Prosper High School Helps Students Create Video PSAs

ERIC Educational Resources Information Center

Cameron, Stacy; Butcher, Adria; Haight, Christine

2012-01-01

Collaboration and coteaching with classroom teachers and campus specialists are the cornerstones of a successful school library program. Whereas collaboration is the process of planning a lesson or unit of instruction, coteaching suggests a much deeper level of collaboration--one in which both the teacher and campus specialist (be it school…

Expanding Persuasion Research: Using More Personally Relevant Issues and Exploring Relevance Perceived from Message Content.

ERIC Educational Resources Information Center

Dewis, Robert; Lee, Wen-Shu

A study explored the impact on junior high school females of "don't smoke" public service announcements (PSAs) created by two groups of high school females. The study extended the research on relevance and persuasion by utilizing intimate issues, and by exploring the potential for increasing message relevance by using persuasive messages…

Public Service Announcements and the Fight against AIDS: A National Survey of Television and Radio Broadcasters' Attitudes and Policies.

ERIC Educational Resources Information Center

Swanson, Douglas J.

A follow-up national study surveyed 500 television and radio broadcasters to further understanding of their role as gatekeepers for public service announcements (PSAs) to educate audiences about AIDS, and to bring about "safe" behavior. Respondents were asked to provide information about their stations, and their stations' use of…

Representation of AIDS in Televised Public Service Announcements: The Discursive Practices of Government in the Constitution of Knowledge about AIDS.

ERIC Educational Resources Information Center

Myrick, Roger; And Others

Using a textualist approach (looking at meaning above and beyond overt message elements), a study examined televised public service announcements (PSAs) about Acquired Immune Deficiency Syndrome (AIDS) produced by the Ad Council and the United States Department of Health and Human Services. Both ads identify young people who should be concerned…

Communicating Prevention: The Effects of the "Keepin' it REAL" Classroom Videotapes and Televised PSAs on Middle-School Students' Substance Use

ERIC Educational Resources Information Center

Warren, Jennifer R.; Hecht, Michael L.; Wagstaff, David A.; Elek, Elvira; Ndiaye, Khadidiatou; Dustman, Patricia; Marsiglia, Flavio F.

2006-01-01

This study sought to determine if exposure to two communication-oriented activities, videotapes and public service announcements, accounts for changes in substance use among adolescents participating in the Drug Resistance Strategies Project's keepin it REAL adolescent substance use prevention curriculum. Middle-school students (4,734, 72% Latino)…

Impact of Norm Perceptions and Guilt on Audience Response to Anti-Smoking Norm PSAs: The Case of Korean Male Smokers

ERIC Educational Resources Information Center

Lee, Hyegyu; Paek, Hye-Jin

2013-01-01

Objective: To examine how norm appeals and guilt influence smokers' behavioural intention. Design: Quasi-experimental design. Setting: South Korea. Method: Two hundred and fifty-five male smokers were randomly assigned to descriptive, injunctive, or subjective anti-smoking norm messages. After they viewed the norm messages, their norm perceptions,…

Effect of inorganic fillers in paper on the adhesion of pressure-sensitive adhesives

Treesearch

Weixu Chen; Xiaoyan Tang; John Considine; Kevin T. Turner

2011-01-01

Inorganic fillers are inexpensive materials used to increase the density, smoothness and other properties of paper that are important for printing. In the current study, the adhesion of pressure-sensitive adhesives (PSAs), a common type of adhesive used in labels and tapes, to papers containing varying amounts and types of fillers is investigated. Papers with three...

Every Drop Counts: Students Develop Public Service Announcements on the Importance of Water Conservation

ERIC Educational Resources Information Center

Stokes, Nina Christiane; Hull, Mary Margaret

2002-01-01

In today's fast-paced, technological world, it is a constant battle for teachers to find new and exciting ways to challenge and engage their students. One success story involves a unique collaborative project that focuses on water resources and conservation in which students design public service announcements (PSAs) to be produced and aired on…

Evaluation of Public Service Advertising Messages with Local and Non-Local Source Attribution: A Controlled Laboratory Experiment.

ERIC Educational Resources Information Center

Lynn, Jerry R.; Gagnard, Alice

A study was conducted to examine message evaluations of selected public service advertisements (PSAs) by a young adult population and to test whether local and nonlocal source attribution would influence those evaluations. In addition, the study investigated the extent to which audience characteristics such as fatalism (the degree to which a…

In-Depth Investigation of Interpersonal Discussions in Response to a Safer Sex Mass Media Campaign

PubMed Central

Helme, Donald W.; Noar, Seth M.; Allard, Suzanne; Zimmerman, Rick S.; Palmgreen, Philip; McClanahan, Karen J.

2015-01-01

We know from theory and limited research that people talk about campaign messages—and that these conversations may play an important role in campaign reach and possibly even efficacy. We know very little, however, about what individuals talk about and with whom they talk. The current study seeks to fill this gap by reporting qualitative and descriptive quantitative data from interviews conducted with 139 young adults about conversations that took place in the context of a large, televised safer sex mass media campaign. Results indicated that public service announcements (PSAs) were often viewed in the company of friends and significant others, and that it was not uncommon for conversations about the PSAs to take place. Three broad categories of conversations that took place involved discussions about PSA realism, the seriousness of the message, and humor. While in some cases conversations seemed to advance the goal of the campaign (e.g., participants discussed sexually transmitted disease [STD] risk and condom use), in other cases they did not (e.g., participants discussed the lack of realism in a particular PSA). Implications for campaign theory, design, and implementation are discussed. PMID:21409674

Validation of the SCEC broadband platform V14.3 simulation methods using pseudo spectral acceleration data

USGS Publications Warehouse

Dreger, Douglas S.; Beroza, Gregory C.; Day, Steven M.; Goulet, Christine A.; Jordan, Thomas H; Spudich, Paul A.; Stewart, Jonathan P.

2015-01-01

This paper summarizes the evaluation of ground motion simulation methods implemented on the SCEC Broadband Platform (BBP), version 14.3 (as of March 2014). A seven-member panel, the authorship of this article, was formed to evaluate those methods for the prediction of pseudo-­‐spectral accelerations (PSAs) of ground motion. The panel’s mandate was to evaluate the methods using tools developed through the validation exercise (Goulet et al. ,2014), and to define validation metrics for the assessment of the methods’ performance. This paper summarizes the evaluation process and conclusions from the panel. The five broadband, finite-source simulation methods on the BBP include two deterministic approaches herein referred to as CSM (Anderson, 2014) and UCSB (Crempien and Archuleta, 2014); a band-­‐limited stochastic white noise method called EXSIM (Atkinson and Assatourians, 2014); and two hybrid approaches, referred to as G&P (Graves and Pitarka, 2014) and SDSU (Olsen and Takedatsu, 2014), which utilize a deterministic Green’s function approach for periods longer than 1 second and stochastic methods for periods shorter than 1 second. Two acceptance tests were defined to validate the broadband finite‐source ground methods (Goulet et al., 2014). Part A compared observed and simulated PSAs for periods from 0.01 to 10 seconds for 12 moderate to large earthquakes located in California, Japan, and the eastern US. Part B compared the median simulated PSAs to published NGA-­‐West1 (Abrahamson and Silva, 2008; Boore and Atkinson, 2008; Campbell and Bozorgnia, 2008; and Chiou and Youngs, 2008) ground motion prediction equations (GMPEs) for specific magnitude and distance cases using a pass-­‐fail criteria based on a defined acceptable range around the spectral shape of the GMPEs. For the initial Part A and Part B validation exercises during the summer of 2013, the software for the five methods was locked in at version 13.6 (see Maechling et al., 2014). In the spring of 2014, additional moderate events were considered for the Part A validation, and additional magnitude and distance cases were considered for the Part B validation, for the software locked in at version 14.3. Several of the simulation procedures, specifically UCSB and SDSU, changed significantly between versions 13.6 and 14.3. The CSM code was not submitted in time for the v14.3 evaluation and its detailed performance is not addressed in this paper. As described in Goulet et al. (2014) and Maechling et al. (2014), the BBP generates a variety of products, including three-­‐component acceleration time series. A series of post-­‐processing codes were developed to provide individual component PSAs and average median horizontal-­‐component PSA (referred to as RotD50; Boore, 2010) for oscillator periods ranging from 0.01 to 10 seconds, as well as median PSA values computed using the NGA-­‐West 1 GMPEs. The BBP was also configured to provide statistical analysis of simulation results relative to recordings (Part A) and GMPEs (Part B) as described further in sections below. As part of our evaluation, we reviewed documentation provided by each of the developers, which included the technical basis behind the methods and the developer’s self-­‐assessments regarding the extrapolation capabilities (in terms of magnitude and distance ranges) of their methods. Two workshops were held in which methods and results were presented, and the panel was given the opportunity to question the developers and to have detailed technical discussions. A SCEC report (Dreger et al., 2013) describes the results of this review for BBP version 13.6. This paper summarizes that work and presents results for the more recent BBP 14.3 validation.

The impact of smoking cues in antismoking messages among intermittent and light smokers.

PubMed

Xu, Jie

2017-01-01

Based on the Limited Capacity Model of Motivated Mediated Message Processing, this study explored the effects of smoking cues in antismoking Public Service Announcements (PSAs) on message processing among intermittent/light smokers and nonsmokers. A 2 (smoking cues: present vs. absent) × 2 (smoking status: smokers vs. nonsmokers) mixed experimental design was conducted. Self-report measures and two physiological measures including skin conductance and heart rate were examined. Messages with smoking cues generated higher levels of arousal (F = 4.57, p = .04), attention (F = 2.51, p = .04), positive message evaluation (F = 28.70, p < .001) and less intent to smoke (F = 26.60, p < .001). Intermittent and light smokers had much stronger reactions to messages containing tobacco-related visuals, including arousal (F = 4.10, p = .04), perceived ad effectiveness (F = 9.24, p = .03) and intent to smoke (F = 22.98, p < .001). The antismoking arguments may have suppressed cue-induced smoking urges, which dampened negative persuasion outcomes. Limitations included the restricted generalisability and the focus on short-term effect. Future research may use a random sample of PSAs with a general population.

Perceived message sensation value (PMSV) and the dimensions and validation of a PMSV scale.

PubMed

Palmgreen, Philip; Stephenson, Michael T; Everett, Maureen W; Baseheart, John R; Francies, Regina

2002-01-01

Sensation seeking has been linked to drug abuse and risky behaviors, and is positively associated with preferences for messages high in sensation value (i.e., perceived to be highly novel, arousing, dramatic, or intense). This suggests the utility of valid and reliable measures of perceived message sensation value (PMSV) in research on information processing, persuasion, and reducing risk-related behaviors. Dimensions and construct validity of a 17-item PMSV scale were examined via 2 studies: 1 of 368 high school students' reactions to televised antimarijuana public service announcements (PSAs) and one of 444 college students' responses to televised anticocaine PSAs. Exploratory and confirmatory factor analyses indicated 3-dimensional solutions for the PMSV scale were nearly identical for high sensation seeking (HSS) and low sensation seeking (LSS) respondents in Study 1 and HSS respondents in Study 2. Total scale alphas were .87 for Study 1 and .93 for Study 2. The PMSV scale and its dimensions (Emotional Arousal, Dramatic Impact, Novelty) were positively correlated with affective response measures in both studies for HSS and LSS. Study 1 also examined cognitive, narrative, and sensory PSA processing, which were found to be positively associated with total PMSV and the Arousal and Dramatic Impact dimensions of PSMV for both HSS and LSS.

"I'm Just There to Ease the Burden": The Parent Support Adviser Role in English Schools and the Question of Emotional Labour

ERIC Educational Resources Information Center

Cullen, Stephen M.; Cullen, Mairi-Ann; Lindsay, Geoff

2013-01-01

In 2005, the Department for Education and Skills announced a 40 million British pound investment in a new school support worker role, the parent support adviser (PSA), for 20 English local authorities. A pilot project ran from 2006-2008 and resulted in the establishment of 717 PSAs in 1167 schools. The national evaluation of the project forms the…

Preliminary Results from an Assimilation of TOMS Aerosol Observations Into the GOCART Model

NASA Technical Reports Server (NTRS)

daSilva, Arlindo; Weaver, Clark J.; Ginoux, Paul; Torres, Omar; Einaudi, Franco (Technical Monitor)

2000-01-01

At NASA Goddard we are developing a global aerosol data assimilation system that combines advances in remote sensing and modeling of atmospheric aerosols. The goal is to provide high resolution, 3-D aerosol distributions to the research community. Our first step is to develop a simple assimilation system for Saharan mineral aerosol. The Goddard Chemistry and Aerosol Radiation model (GOCART) provides accurate 3-D mineral aerosol size distributions that compare well with TOMS satellite observations. Surface, mobilization, wet and dry deposition, convective and long-range transport are all driven by assimilated fields from the Goddard Earth Observing System Data Assimilation System, GEOS-DAS. Our version of GOCART transports sizes from.08-10 microns and only simulates Saharan dust. TOMS radiance observations in the ultra violet provide information on the mineral and carbonaceous aerosol fields. We use two main observables in this study: the TOMS aerosol index (AI) which is directly related to the ratio of the 340 and 380 radiances and the 380 radiance. These are sensitive to the aerosol optical thickness, the single scattering albedo and the height of the aerosol layer. The Goddard Aerosol Assimilation System (GAAS) uses the Data Assimilation Office's Physical-space Statistical Analysis System (PSAS) to combine TOMS observations and GOCART model first guess fields. At this initial phase we only assimilate observations into the the GOCART model over regions of Africa and the Atlantic where mineral aerosols dominant and carbonaceous aerosols are minimal, Our preliminary results during summer show that the assimilation with TOMS data modifies both the aerosol mass loading and the single scattering albedo. Assimilated aerosol fields will be compared with assimilated aerosol fields from GOCART and AERONET observations over Cape Verde.

The effects of retrieval ease on health issue judgments: implications for campaign strategies.

PubMed

Chang, Chingching

2010-12-01

This paper examines the effects of retrieving information about a health ailment on judgments of the perceived severity of the disease and self-efficacy regarding prevention and treatment. The literature on metacognition suggests that recall tasks render two types of information accessible: the retrieved content, and the subjective experience of retrieving the content. Both types of information can influence judgments. Content-based thinking models hold that the more instances of an event people can retrieve, the higher they will estimate the frequency of the event to be. In contrast, experience-based thinking models suggest that when people experience difficulty in retrieving information regarding an event, they rate the event as less likely to occur. In the first experiment, ease of retrieval was manipulated by asking participants to list either a high or low number of consequences of an ailment. As expected, retrieval difficulty resulted in lower perceived disease severity. In the second experiment, ease of retrieval was manipulated by varying the number of disease prevention or treatment measures participants attempted to list. As predicted, retrieval difficulty resulted in lower self-efficacy regarding prevention and treatment. In experiment three, when information regarding a health issue was made accessible by exposure to public service announcements (PSAs), ease-of-retrieval effects were attenuated. Finally, in experiment four, exposure to PSAs encouraged content-based judgments when the issue was of great concern.

Constructing vulnerabilty and protective measures indices for the enhanced critical infrastructure protection program.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fisher, R. E.; Buehring, W. A.; Whitfield, R. G.

2009-10-14

The US Department of Homeland Security (DHS) has directed its Protective Security Advisors (PSAs) to form partnerships with the owners and operators of assets most essential to the Nation's well being - a subclass of critical infrastructure and key resources (CIKR) - and to conduct site visits for these and other high-risk assets as part of the Enhanced Critical Infrastructure Protection (ECIP) Program. During each such visit, the PSA documents information about the facility's current CIKR protection posture and overall security awareness. The primary goals for ECIP site visits (DHS 2009) are to: (1) inform facility owners and operators ofmore » the importance of their facilities as an identified high-priority CIKR and the need to be vigilant in light of the ever-present threat of terrorism; (2) identify protective measures currently in place at these facilities, provide comparisons of CIKR protection postures across like assets, and track the implementation of new protective measures; and (3) enhance existing relationships among facility owners and operators; DHS; and various Federal, State, local tribal, and territorial partners. PSAs conduct ECIP visits to assess overall site security; educate facility owners and operators about security; help owners and operators identify gaps and potential improvements; and promote communication and information sharing among facility owners and operators, DHS, State governments, and other security partners. Information collected during ECIP visits is used to develop metrics; conduct sector-by-sector and cross-sector vulnerability comparisons; identify security gaps and trends across CIKR sectors and subsectors; establish sector baseline security survey results; and track progress toward improving CIKR security through activities, programs, outreach, and training (Snyder 2009). The data being collected are used in a framework consistent with the National Infrastructure Protection Plan (NIPP) risk criteria (DHS 2009). The NIPP framework incorporates consequence, threat, and vulnerability components and addresses all hazards. The analysis of the vulnerability data needs to be reproducible, support risk analysis, and go beyond protection. It also needs to address important security/vulnerability topics, such as physical security, cyber security, systems analysis, and dependencies and interdependencies. This report provides an overview of the approach being developed to estimate vulnerability and provide vulnerability comparisons for sectors and subsectors. the information will be used to assist DHS in analyzing existing protective measures and vulnerability at facilities, to identify potential ways to reduce vulnerabilities, and to assist in preparing sector risk estimates. The owner/operator receives an analysis of the data collected for a specific asset, showing a comparison between the facility's protection posture/vulnerability index and those of DHS sector/subsector sites visited. This comparison gives the owner/operator an indication of the asset's security strengths and weaknesses that may be contributing factors to its vulnerability and protection posture. The information provided to the owner/operator shows how the asset compares to other similar assets within the asset's sector or subsector. A 'dashboard' display is used to illustrate the results in a convenient format. The dashboard allows the owner/operator to analyze the implementation of additional protective measures and to illustrate how such actions would impact the asset's Protective Measures Index (PMI) or Vulnerability Index (VI).« less

Does three-dimensional transesophageal echocardiography provide incremental value in percutaneous closure of ascending aortic pseudoaneurysm?

PubMed

Elkaryoni, Ahmed; Hsiung, Ming C; Arisha, Mohammed J; Ahmad, Amier; Nanda, Navin C; Mohamed, Ahmed H; Attia, Doaa; Sachdeva, Ankush; Singh, Lovepreet; Yin, Wei-Hsian

2017-07-01

Ascending aortic pseudoaneurysms (AO PSAs), if left untreated, are complicated by a high rate of rupture resulting in significant morbidity and mortality. New transcatheter modalities have emerged as acceptable surgical alternatives for their management. We present a case of an ascending aortic PSA in which intraoperative two- and three-dimensional transesophageal echocardiography (2DTEE and 3DTEE) provided a comprehensive assessment of the PSA in pre- and postclosure settings. © 2017, Wiley Periodicals, Inc.

The Molecular Mechanism of the Supra-Additive Response of Prostate Cancer to Androgen Ablation and Radiotherapy

DTIC Science & Technology

2001-02-01

being seen approximately every 6 months PAP levels was found (Table 3). Pretreatment PSAs >10 with interval history, physical examination, serum PSA...Aknowledgments-This study was supported in part by Depart- 1507 � I. J. Radiation Oncology 0 Biology @ Physics Volume 48, Number 5, 2000 of hormone...than nonspecific one standard deviation above and below the mean. 1510 I. J. Radiation Oncology 0 Biology 0 Physics Volume 48, Number 5, 2000 significant

Large Amplitude Oscillatory Shear (LAOS) of Acrylic Emulsion-Based Pressure Sensitive Adhesives (PSAs)

NASA Astrophysics Data System (ADS)

Zhang, Sipei; Nakatani, Alan; Griffith, William

Large Amplitude Oscillatory Shear (LAOS) testing has recently taken on renewed interest in the rheological community. It is a very useful tool to probe the viscoelastic response of materials in the non-linear regime. Much of the discussion on polymers in the LAOS field has focused on melts in or near the terminal flow regime. Here we present a LAOS study conducted on a commercial rheometer for acrylic emulsion-based pressure sensitive adhesive (PSA) films in the plateau regime. The films behaved qualitatively similar over an oscillation frequency range of 0.5-5 rad/s. From Fourier transform analysis, the fifth or even the seventh order harmonic could be observed at large applied strains. From stress decomposition analysis or Lissajous curves, inter-cycle elastic softening, or type I behavior, was observed for all films as the strain increases, while intra-cycle strain hardening occurred at strains in the LAOS regime. Overall, as acid content increases, it was found that the trend in elasticity under large applied strains agreed very well with the trend in cohesive strength of the films.

Imprint of Rupture Directivity From Ground Motions of the 24 August 2016 Mw6.2 Central Italy Earthquake

NASA Astrophysics Data System (ADS)

Ren, Yefei; Wang, Hongwei; Wen, Ruizhi

2017-12-01

An Mw6.2 earthquake occurred in Central Italy on 24 August 2016. The objective of this study was to reveal the imprint of rupture directivity using the strong motion recordings. The strong motion stations were separated into two groups: southeast (SE) and northwest (NW). The effects of rupture directivity on the peak ground acceleration (PGA), peak ground velocity (PGV), and pseudo spectral acceleration (PSA) were investigated. The observed values of these parameters were compared with predicted values derived from ground motion prediction equations. The results showed that the residuals between the observed and predicted PGAs, PGVs, and PSAs at periods of T < 1 s were correlated significantly with azimuth angle and generally larger in the NW sector, reflecting that the observed PGAs, PGVs, and short-period PSAs in the NW sector were generally larger than observed in the SE sector. These phenomena are accordant with the theoretical law that the rupture directivity causes higher amplitudes in the forward direction compared with the backward direction. Finally, selected source rupture parameters were inverted using PGAs and PGVs. This revealed that the rupture was predominantly unilateral rupture, the major rupture was likely at an azimuth of 360°, and the length of the major rupture was proportional to 70%-100% of the total ruptured fault, confirming that rupture directivity caused the differences in the ground motions observed in the SE and NW sectors.

Priming effect of antismoking PSAs on smoking behaviour: a pilot study.

PubMed

Harris, Jennifer L; Pierce, Melissa; Bargh, John A

2014-07-01

Social marketing is commonly proposed to counteract advertising and other messages that promote unhealthy products. However, public service campaigns can also 'boomerang' or ironically increase the unhealthy behaviours they are designed to discourage. The present study examined whether antismoking public service announcements (PSAs) could increase smoking behaviour immediately following exposure. In an experimental study, 56 smokers were randomly assigned to watch a short television segment with a commercial break that included either (1) a Philip Morris 'QuitAssist' PSA; (2) a Legacy 'truth' antismoking PSA; or (3) a control PSA. Smoking behaviour was assessed during a short break immediately following television viewing. Participants who saw the Philip Morris antismoking PSA were significantly more likely to smoke during a break (42%) compared with participants in the control condition (11%), and participants in the 'truth' condition were marginally more likely to smoke (33%). These differences could not be explained by factors such as mood or level of addiction, and effects occurred outside of participants' conscious awareness. These findings provide preliminary evidence that antismoking campaigns could ironically increase immediate smoking behaviours among smokers. The long-term benefits of proven public health campaigns, including 'truth,' are likely to outweigh any short-term boomerang effects. However, industry-sponsored messages in which companies have an economic incentive to increase consumption behaviours should be treated with scepticism and evaluated independently. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Initiating Event Analysis of a Lithium Fluoride Thorium Reactor

NASA Astrophysics Data System (ADS)

Geraci, Nicholas Charles

The primary purpose of this study is to perform an Initiating Event Analysis for a Lithium Fluoride Thorium Reactor (LFTR) as the first step of a Probabilistic Safety Assessment (PSA). The major objective of the research is to compile a list of key initiating events capable of resulting in failure of safety systems and release of radioactive material from the LFTR. Due to the complex interactions between engineering design, component reliability and human reliability, probabilistic safety assessments are most useful when the scope is limited to a single reactor plant. Thus, this thesis will study the LFTR design proposed by Flibe Energy. An October 2015 Electric Power Research Institute report on the Flibe Energy LFTR asked "what-if?" questions of subject matter experts and compiled a list of key hazards with the most significant consequences to the safety or integrity of the LFTR. The potential exists for unforeseen hazards to pose additional risk for the LFTR, but the scope of this thesis is limited to evaluation of those key hazards already identified by Flibe Energy. These key hazards are the starting point for the Initiating Event Analysis performed in this thesis. Engineering evaluation and technical study of the plant using a literature review and comparison to reference technology revealed four hazards with high potential to cause reactor core damage. To determine the initiating events resulting in realization of these four hazards, reference was made to previous PSAs and existing NRC and EPRI initiating event lists. Finally, fault tree and event tree analyses were conducted, completing the logical classification of initiating events. Results are qualitative as opposed to quantitative due to the early stages of system design descriptions and lack of operating experience or data for the LFTR. In summary, this thesis analyzes initiating events using previous research and inductive and deductive reasoning through traditional risk management techniques to arrive at a list of key initiating events that can be used to address vulnerabilities during the design phases of LFTR development.

Projections of Demand for Waterborne Transportation, Ohio River Basin, 1980, 1990, 2000, 2020, 2040. Volume 4. Group II. Petroleum Fuels.

DTIC Science & Technology

1980-12-01

for1980 and 1985 (OaK Ridge, TN: ORNL , 1978), Table 1. I -11- B-3. Residual Fuel Oil This group mainly includes No. 5 and No. 6 fuel oils. They are used...types of fuels was then distributed to the PSAs. This projection was based on projections from two different sources. Oak Ridge National Laboratory ( ORNL ...nine census regions, 50 states and 173 BEAs. The supply and demand projectiSns were made for seven fuel types and four final consuming sectors. ORNL

Minimally invasive video-assisted thyroidectomy: four-year experience of a single team in a General Surgery Unit.

PubMed

Scerrino, G; Paladino, N C; Di Paola, V; Morfino, G; Inviati, A; Amodio, E; Gulotta, G; Bonventre, S

2013-06-01

Minimally invasive video-assisted thyroidectomy (MIVAT) is a surgical technique that has showed increasingly good results, particularly in endocrine surgery centers. The aim of this prospective, non-randomized study was to evaluate feasibility, advantages and critical aspects of MIVAT in a general surgery unit. Two hundred twenty-four patients underwent total thyroidectomy for benign thyroid disease from May, 2008 to April, 2011. They were divided into two groups: one underwent conventional thyroidectomy (CT), and the other underwent MIVAT. The inclusion criteria were thyroid volume ≤35 mL and main nodule size ≤35 mm. For each patient, socio-demographic variables, hospitalization data and outcome measures (complication rate, operating time, post-operative pain, observer and patient scar assessment scale [OSAS and PSAS, respectively]) were collected. Multivariate regression analyses were done to assess the principal covariates affecting these outcome measures. There were 125 MIVATs and 99 CTs performed. The two groups were characterized by difference in age (38.4 vs. 50.9 years) and thyroid volume (18.6 vs. 23.3 mL). OSAS/PSAS scores were statistically significant in the MIVAT group (P<0.001 and P<0.001, respectively) even after adjusting for age and thyroid volume. Complication rate was similar in the two groups. MIVAT significantly decreased postoperative pain and improved cosmetic results. It can be performed in younger patients and in all cases in which there is a clear indication for the procedure. Its advantages were confirmed in a general surgery unit where correct indications were followed.

A randomized controlled trial of mindfulness meditation for chronic insomnia.

PubMed

Ong, Jason C; Manber, Rachel; Segal, Zindel; Xia, Yinglin; Shapiro, Shauna; Wyatt, James K

2014-09-01

To evaluate the efficacy of mindfulness meditation for the treatment of chronic insomnia. Three-arm, single-site, randomized controlled trial. Academic medical center. Fifty-four adults with chronic insomnia. Participants were randomized to either mindfulness-based stress reduction (MBSR), mindfulness-based therapy for insomnia (MBTI), or an eight-week self-monitoring (SM) condition. Patient-reported outcome measures were total wake time (TWT) from sleep diaries, the pre-sleep arousal scale (PSAS), measuring a prominent waking correlate of insomnia, and the Insomnia Severity Index (ISI) to determine remission and response as clinical endpoints. Objective sleep measures were derived from laboratory polysomnography and wrist actigraphy. Linear mixed models showed that those receiving a meditation-based intervention (MBSR or MBTI) had significantly greater reductions on TWT minutes (43.75 vs 1.09), PSAS (7.13 vs 0.16), and ISI (4.56 vs 0.06) from baseline-to-post compared to SM. Post hoc analyses revealed that each intervention was superior to SM on each of the patient-reported measures, but no significant differences were found when comparing MBSR to MBTI from baseline-to-post. From baseline to 6-month follow-up, MBTI had greater reductions in ISI scores than MBSR (P < 0.05), with the largest difference occurring at the 3-month follow-up. Remission and response rates in MBTI and MBSR were sustained from post-treatment through follow-up, with MBTI showing the highest rates of treatment remission (50%) and response (78.6%) at the 6-month follow-up. Mindfulness meditation appears to be a viable treatment option for adults with chronic insomnia and could provide an alternative to traditional treatments for insomnia. Mindfulness-Based Approaches to Insomnia: clinicaltrials.gov, identifier: NCT00768781. © 2014 Associated Professional Sleep Societies, LLC.

Salud para su Corazón: a community-based Latino cardiovascular disease prevention and outreach model.

PubMed

Alcalay, R; Alvarado, M; Balcazar, H; Newman, E; Huerta, E

1999-10-01

Cardiovascular disease (CVD) is the leading cause of death for Latinos living in the United States. This population is generally unaware of important lifestyle or behavioral changes that can prevent CVD. The National Heart, Lung, and Blood Institute (NHLBI) designed and implemented Salud para su Corazón (Health for Your Heart), a culturally appropriate, community-based, theory-driven intervention model. NHLBI's goals were: (1) to design an intervention model appropriate to Latino populations; (2) to pilot test the model in a specific community with the objectives of increasing awareness about heart disease, raising knowledge about CVD prevention, and promoting heart-healthy lifestyles; and (3) to disseminate the model and the materials developed to other communities with similar needs. An agency-community partnership, under the leadership of the Community Alliance for Heart Health, guided all stages of the community intervention project. The multimedia bilingual community intervention included television telenovela format public service announcements (PSAs), radio programs, brochures, recipe booklets, charlas, a promotores training manual, and motivational videos. An evaluation survey assessed the impact of the intervention. A pre-post intervention survey was conducted with more than 300 participants, and results showed that the respondents were substantially more aware of risk factors for CVD, and had greatly increased their knowledge of ways to prevent heart disease. Dissemination efforts have resulted in numerous requests by health organizations, universities, and health maintenance organizations (HMOs) for educational materials and communication strategies produced by Salud para su Corazón. In addition, Univision, the largest Spanish-language broadcast television network, is airing the initiative's PSAs. Also, training seminars for promotores are being conducted in different regions of the United States, and several locations are planning to replicate this study.

Designing Skin Cancer Prevention Messages: Should We Emphasize Gains or Losses? Message Framing, Risk Type, and Prior Experience.

PubMed

Lee, Moon J; Kang, Hannah

2018-05-01

To test whether message framing (ie, gain vs. loss) and risk type (ie, health vs appearance risk) in skin cancer prevention messages interact with one's prior experience. Two experiments with a 2 (message framing: gain vs loss) × 2 (risk type: health vs appearance risk) factorial design were conducted. The participants were given a URL to the experiment website via e-mail. On the first page of the website, the participants were told that they would be asked to evaluate a skin cancer print public service announcement (PSA): Online experiments. A total of 397 individuals participated (236 for experiment 1 and 161 for experiment 2). Apparatus: Four versions of the skin cancer print PSAs were developed. Four PSAs were identical except for the 2 manipulated components: message framing and risk type. Measures were adopted from Cho and Boster (message framing), Jones and Leary and Kiene et al. (risk type), De Vries, Mesters, van't Riet, Willems, and Reubsaet and Knight, Kirincich, Farmer, and Hood (prior experience), and Hammond, Fong, Zanna, Thrasher, and Borland and Hoffner and Ye (behavioral intent). General linear models were used to test hypotheses. Three-way interactions among message framing, risk type, and prior experience were found: When the intent of the message was to encourage sunscreen use, the effects of message framing and risk type were shown to be the exact opposite directions from when the intent was to discourage indoor/outdoor tanning. To discourage tanning among those with prior experience, messages emphasizing losses in terms of one's health will work better. For those with no prior experience, messages emphasizing potential appearance losses will work better for discouraging tanning while messages emphasizing gains like improving appearance will do a better job in encouraging sunscreen use.

Assessing the growth and recovery of Salmonella Enteritidis SE86 after sodium dichloroisocyanurate exposure

PubMed Central

Ferreira, Fernanda Stoduto; Horvath, Mariana Bandeira; Tondo, Eduardo Cesar

2013-01-01

The objective of the present study was to assess the growth and the recovery of Salmonella (S.) Enteritidis SE86 in different diluents, culture media and using different plating methods after the exposure to 200 mg/kg sodium dichloroisocyanurate (NaDCC). Before and after NaDCC exposure, SE86 was cultured at 30 °C and 7 °C in the following diluents: Peptone water (P), Saline solution (SaS), Peptone water+Saline solution (P+SaS), Peptone water+Tween 80+Lecithin+Sodium thiosulfate (P+N) and Saline solution+Tween 80+Lecithin+Sodium thiosulfate (SaS+N). The SaS diluent was chosen because it was able to maintain cells viable without growth and was further used for plating SE86 on non selective medium (Tryptic Soy Agar-TSA) and on selective media (Mannitol Lysine Crystal Violet Brilliant Green Agar-MLCB; Brilliant Green Agar-BGA; Salmonella Shigella Agar-SS and Xylose Lysine Dextrose–XLD). The Thin Agar Layer method (TAL) i.e., selective media overlayed with non selective TSA was also evaluated. Results indicated that SE86 not exposed to NaDCC was able to grow in P, P+N, SaS+N and P+SaS, but not in SaS, that was able to maintain cells viable. SE86 exposed to NaDCC demonstrated similar counts after dilution in SaS and the plating on non selective TSA, selective media MLCB, BGA, SS and XLD and on TAL media. SE86, S. Typhimurium and S. Bredeney, exposed or not exposed to NaDCC, showed no significant differences in counts on TSA, XLD and XLD overlayed with TSA, suggesting that all those media may be used to quantify NaDCC-exposed Salmonella by plating method. PMID:24516446

Mindfulness Meditation and CBT for Insomnia: A Naturalistic 12-Month Follow-up

PubMed Central

Ong, Jason C.; Shapiro, Shauna L.; Manber, Rachel

2016-01-01

A unique intervention combining mindfulness meditation with cognitive behavioral therapy for insomnia (CBT-I) has been shown to have acute benefits at post-treatment in an open label study. The aim of the present study was to examine the long-term effects of this integrated intervention on measures of sleep and sleep-related distress in an attempt to characterize the natural course of insomnia following this treatment and to identify predictors of poor long-term outcome. Analyses were conducted on 21 participants who provided follow-up data at 6 and 12 months post treatment. At each time point, participants completed one week of sleep and meditation diaries and questionnaires related to mindfulness, sleep, and sleep-related distress, including the Pre-Sleep Arousal Scale (PSAS), Glasgow Sleep Effort Scale (GSES), Kentucky Inventory of Mindfulness Skills (KIMS), and the Insomnia Episode Questionnaire. Analyses examining the pattern of change across time (baseline, end-of-treatment, 6 month, and 12 month) revealed that several sleep-related benefits were maintained during the 12-month follow-up period. Participants who reported at least one insomnia episode (≥ 1 month) during the follow-up period had higher scores on the PSAS (p < .05) and GSES (p < .05) at end-of-treatment compared to those with no insomnia episodes. Correlations between mindfulness skills and insomnia symptoms revealed significant negative correlations (p < .05) between mindfulness skills and daytime sleepiness at each of the three time points but not with nocturnal symptoms of insomnia. These results suggest that most sleep-related benefits of an intervention combining CBT-I and mindfulness meditation were maintained during the 12-month follow-up period with indications that higher pre-sleep arousal and sleep effort at end-of-treatment constitute a risk for occurrence of insomnia during the 12 months following treatment. PMID:19114261

Lack of Resilience Is Related to Stress-Related Sleep Reactivity, Hyperarousal, and Emotion Dysregulation in Insomnia Disorder.

PubMed

Palagini, Laura; Moretto, Umberto; Novi, Martina; Masci, Isabella; Caruso, Danila; Drake, Christopher L; Riemann, Dieter

2018-05-15

According to the diathesis-stress model of insomnia, insomnia may develop in vulnerable individuals in response to stress. Resilience is a psychobiological factor that determines an individual's capacity to adapt successfully to stressful events and low resilience increases vulnerability for development of mental disorders. The aim was to explore resilience in subjects with insomnia and its relationship with the factors that contribute to its development and perpetuation. The study consisted of 58 subjects with Insomnia Disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition and 38 good sleepers. Resilience Scale for Adults (RSA), Ford Insomnia Response to Stress Test (FIRST), Pre-sleep Arousal Scale (PSAS), and Difficulties in Emotion Regulation Scale (DERS) were administered while taking into account psychiatric symptoms. Differences in means between groups were assessed using t test or Mann-Whitney U /Wilcoxon test. Linear/multivariable regression analyses and mediation analyses were performed. Subjects with insomnia (24 females, mean age 49 ± 2.1 years) had lower RSA and higher FIRST, DERS, and PSAS scores than good sleepers (22 females, mean age 47.2 ± 1.2 years). After controlling for anxiety/depressive symptoms, low resilience correlated with high stress-related sleep reactivity ( P = .004), pre-sleep cognitive hyperarousal ( P = .01) and emotion dysregulation ( P = .01). Emotion dysregulation mediated the relationship between low resilience and cognitive hyperarousal (Z = 2.06, P = .03). Subjects with insomnia showed low resilience, which was related to high stress-related sleep reactivity, emotional dysregulation, and hyperarousal. If resilience helps to minimize the extent of pathogenesis in the developmental process, an early identification of vulnerable candidates should be useful for preventing insomnia development and maintenance. A commentary on this article appears in this issue on page 709. © 2018 American Academy of Sleep Medicine.

Psychometric properties of the medical outcomes study: social support survey among methadone maintenance patients in Ho Chi Minh City, Vietnam: a validation study.

PubMed

Khuong, Long Quynh; Vu, Tuong-Vi Thi; Huynh, Van-Anh Ngoc; Thai, Truc Thanh

2018-02-14

Social support plays a crucial role in the treatment and recovery process of patients engaging in methadone maintenance treatment (MMT). However, there is a paucity of research about social support among MMT patients, possibly due to a lack of appropriate measuring tools. This study aimed to evaluate the psychometric properties of the Vietnamese version of the Medical Outcomes Study: Social Support Survey (MOS-SSS) among MMT patients. A cross-sectional survey of 300 patients was conducted in a methadone clinic in Ho Chi Minh City, Vietnam. MMT patients who agreed to participate in the study completed a face-to-face interview in a private room. The MOS-SSS was translated into Vietnamese using standard forward-backward process. Internal consistency was measured by Cronbach's alpha. The intra-class correlation coefficient was used to determine the test-retest reliability of the MOS-SSS in 75 participants two weeks after the first survey. Concurrent validity of the MOS-SSS was evaluated by correlations with the Multidimensional Scale of Perceived Social Support (MSPSS) and the Perceived Stigma of Addiction Scale (PSAS). Construct validity was investigated by confirmatory factor analysis. The MOS-SSS had good internal consistency with Cronbach's alpha from 0.95 to 0.97 for the four subscales and 0.97 for the overall scale. The two-week test-retest reliability was at moderate level with intra-class correlation coefficients of 0.61-0.73 for the four subscales and 0.76 for the overall scale. Strong significant correlations between the MOS-SSS and the MSPSS (r = 0.77; p < 0.001) and the PSAS (r = - 0.76; p < 0.001) indicated good concurrent validity. Construct validity of the MOS-SSS was established since a final four-factor model fitted the data well with Comparative Fit Index (0.97), Tucker-Lewis Index (0.97), Standardized Root Mean Square Residual (0.03) and Root Mean Square Error of Approximation (0.068; 90% CI = 0.059-0.077). The MOS-SSS is a reliable and valid tool for measuring social support in Vietnamese MMT patients. Further studies among methadone patients at different stages of their treatment and among those from different areas of Vietnam are needed.

Assessing the TARES as an ethical model for antismoking ads.

PubMed

Lee, Seow Ting; Cheng, I-Huei

2010-01-01

This study examines the ethical dimensions of public health communication, with a focus on antismoking public service announcements (PSAs). The content analysis of 826 television ads from the U.S. Centers for Disease Control and Prevention's (CDC) Media Campaign Resource Center is an empirical testing of Baker and Martinson's (2001) TARES Test that directly examines persuasive messages for truthfulness, authenticity, respect, equity, and social responsibility. In general, the antismoking ads score highly on ethicality. There are significant relationships between ethicality and message attributes (thematic frame, emotion appeal, source, and target audience). Ads that portrayed smoking as damaging to health and socially unacceptable score lower in ethicality than ads that focus on tobacco industry manipulation, addiction, dangers of secondhand smoke, and cessation. Emotion appeals of anger and sadness are associated with higher ethicality than shame and humor appeals. Ads targeting teen/youth audiences score lower on ethicality than ads targeting adult and general audiences. There are significant differences in ethicality based on source; ads produced by the CDC rate higher in ethicality than other sources. Theoretical implications and practical recommendations are discussed.

The effects of message framing, involvement, and nicotine dependence on anti-smoking public service announcements.

PubMed

Jung, Wan S; Villegas, Jorge

2011-01-01

Anti-smoking Public Service Announcements (PSAs) typically emphasize the negative consequences of failing to quit smoking (negative frame), as opposed to emphasizing the benefits of quitting (positive frame). However, stressing the benefits of quitting sometimes produces better communication outcomes. Previous research on message framing has tried to identify factors affecting the impact of positive framing and negative framing. Data were collected on 188 undergraduates attending a southeastern university in the United States who were assigned randomly to view either positive or negative messages. Our study found that involvement and nicotine dependence moderated the impact of framed smoking-cessation messages on attitude toward the ad.

Phase sensitive amplification in integrated waveguides (Conference Presentation)

NASA Astrophysics Data System (ADS)

Schroeder, Jochen B.; Zhang, Youngbin; Husko, Chad A.; LeFrancois, Simon; Eggleton, Benjamin J.

2017-02-01

Phase sensitive amplification (PSA) is an attractive technology for integrated all-optical signal processing, due to it's potential for noiseless amplification, phase regeneration and generation of squeezed light. In this talk I will review our results on implementing four-wave-mixing based PSA inside integrated photonic devices. In particular I will discuss PSA in chalcogenide ridge waveguides and silicon slow-light photonic crystals. We achieve PSA in both pump- and signal-degenerate schemes with maximum extinction ratios of 11 (silicon) and 18 (chalcogenide) dB. I will further discuss the influence of two-photon absorption and free carrier effects on the performance of silicon-based PSAs.

Get real: how current behavior influences perceptions of realism and behavioral intent for public service announcements.

PubMed

Nelson, Michelle R; Zhu, Xuan; Li, Yingying; Fiese, Barbara; Koester, Brenda

2015-01-01

This research examined how realism and current behavior influence message reception and processing for public service announcements (PSAs) designed to help parents with meal planning. Findings from 19 in-depth interviews revealed that the perceived realism of the message, the similarity, and the wishful identification with informants' lives influenced message acceptance, in line with the Message Interpretation Process (MIP) model. Results of an online survey with mothers show that realism matters more for those individuals who already engage in the featured behavior. In line with theory, "experts" (meal planners) show increased behavioral intent of the featured behaviors when viewing the more realistic PSA.

Effects of message framing in anti-binge drinking PSAs: the moderating role of counterfactual thinking.

PubMed

Baek, Tae Hyun; Shen, Lijiang; Reid, Leonard N

2013-01-01

This experiment examined the interaction effects of message framing and counterfactual thinking on attitudes toward binge drinking and behavioral intentions. Data from a 2 (message framing: gain vs. loss) × 2 (counterfactual thinking priming: additive vs. subtractive) between-subjects factorial design showed that a gain-framed message resulted in lower binge drinking intentions than did a loss-framed message after subjects engaged in additive counterfactual thinking. The effects of a loss-framed message on binge drinking intentions occurred when subtractive counterfactual thinking was induced. Theoretical and practical implications for anti-binge drinking public service announcements are discussed.

Children's catching performance when the demands on the postural system is altered.

PubMed

Angelakopoulos, Georgios T; Tsorbatzoudis, Haralambos; Grouios, George

2014-07-01

In many dynamic interceptive actions performers need to integrate activity of manual and postural subsystems for successful performance. Groups of different skill level (poor and good catchers), (mean age = 9.1 and 9.4 respectively) were required to perform one-handed catches under different postural constraints: standing; standing in contact with a postural support aid by their side (PSAS) or to the left of their trunk (PSAF); Tandem; and sitting (control). Results revealed that, for poor catchers, the number of successful catches increased and grasp errors decreased significantly when sitting and with both postural aids in comparison with standing alone and Tandem conditions. Kinematic analyses showed that the postural aid devices reduced head sway in the anterior-posterior direction, while the PSAF reduced lateral head sway. The poor catchers' performance benefited from an enlarged support surface, and reduction of lateral sway. Good catchers performed successfully under all task constraints, signifying the existence of a functional relationship between postural and grasping subsystems during performance. The results are discussed in the frame of Bernstein's (1967) and Newell's (1986) theory.

Silicone Liner-Free Pressure Sensitive Adhesive Labels

NASA Astrophysics Data System (ADS)

Empereur, Johanne; Chaussy, Didier; Belgacem, Mohamed Naceur

2008-08-01

Pressure sensitive adhesives (PSA) were microencapsulated using simple and complex coacervation and aminoplaste. The microcapsules thus prepared were characterized by FTIR spectroscopy, particle size distribution, rheological behavior and peeling tests. The microcapsules were isolated and found to be out of sticky indicating that the PSAs were indeed encapsulated. The prepared suspensions were deposited at the surface of a paper sheets and the dried labels were then pressed against each other. The ensuing complex was then characterized in terms of peeling forces and showed that the encapsulation using aminoplaste technique of a commercial PSA yielded peel energy of 170 J/m2, which constitutes the recovering of about 68% of the adhesive power of the original non encapsulated PSA.

Preliminary Results from an Assimilation of Saharan Dust Using TOMS Radiances and the GOCART Model

NASA Technical Reports Server (NTRS)

Weaver, C. J.; daSilva, Arlindo; Ginoux, Paul; Torres, Omar; Einaudi, Franco (Technical Monitor)

2000-01-01

At NASA Goddard we are developing a global aerosol data assimilation system that combines advances in remote sensing and modeling of atmospheric aerosols. The goal is to provide high resolution, 3-D aerosol distributions to the research community. Our first step is to develop a simple assimilation system for Saharan mineral aerosol. The Goddard Chemistry and Aerosol Radiation model (GOCART) provides accurate 3-D mineral aerosol size distributions. Surface mobilization, wet and dry deposition, convective and long-range transport are all driven by assimilated fields from the Goddard Earth Observing System Data Assimilation System, GEOS-DAS. Our version of GOCART transports sizes from .08-10 microns and only simulates Saharan dust. We draw the assimilation to two observables in this study: the TOMS aerosol index (Al) which is directly related to the ratio of the 340 and 380 radiances and the 380 radiance alone. The forward model that simulates the observables requires the aerosol optical thickness, the single scattering albedo and the height of the aerosol layer from the GOCART fields. The forward model also requires a refractive index for the dust. We test three index values to see which best fits the TOMS observables. These are 1) for Saharan dust reported by Patterson, 2) for a mixture of Saharan dust and a highly reflective material (sea salt or sulfate) and 3) for pure illite. The assimilation works best assuming either pure illite or the dust mixture. Our assimilation cycle first determines values of the aerosol index (Al) and the radiance at 380 nm based on the GOCART aerosol fields. Differences between the observed and GOCART model calculated Al and 380 nm radiance are first analyzed horizontally using the Physical-space Statistical Analysis System (PSAS). A quasi-Newton iteration is then performed to produce analyzed 3D aerosol fields according to parameterized background and observation error covariances. We only assimilate observations into the the GOCART model over regions of Africa and the Atlantic where mineral aerosols are dominant and carbonaceous aerosols are minimal.

Cost-Effectiveness Analysis of Prophylaxis Treatment Strategies to Reduce the Incidence of Febrile Neutropenia in Patients with Early-Stage Breast Cancer or Non-Hodgkin Lymphoma.

PubMed

Fust, Kelly; Li, Xiaoyan; Maschio, Michael; Villa, Guillermo; Parthan, Anju; Barron, Richard; Weinstein, Milton C; Somers, Luc; Hoefkens, Caroline; Lyman, Gary H

2017-04-01

The objective of this study was to evaluate the cost effectiveness of no prophylaxis, primary prophylaxis (PP), or secondary prophylaxis (SP) with granulocyte colony-stimulating factors (G-CSFs), i.e., pegfilgrastim, lipegfilgrastim, filgrastim (6- and 11-day), or lenograstim (6- and 11-day), to reduce the incidence of febrile neutropenia (FN) in patients with stage II breast cancer receiving TC (docetaxel, cyclophosphamide) and in patients with non-Hodgkin lymphoma (NHL) receiving R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) over a lifetime horizon from a Belgian payer perspective. A Markov cycle tree tracked FN events during chemotherapy (3-week cycles) and long-term survival (1-year cycles). Model inputs, including the efficacy of each strategy, risk of reduced relative dose intensity (RDI), and the impact of RDI on mortality, utilities, and costs (in €; 2014 values) were estimated from public sources and the published literature. Incremental cost-effectiveness ratios (ICERs) were assessed for each strategy for costs per FN event avoided, life-year (LY) saved, and quality-adjusted LY (QALY) saved. LYs and QALYs saved were discounted at 1.5% annually. Deterministic and probabilistic sensitivity analyses (DSAs and PSAs) were conducted. Base-case ICERs for PP with pegfilgrastim relative to SP with pegfilgrastim were €15,500 per QALY and €14,800 per LY saved for stage II breast cancer and €7800 per QALY and €6900 per LY saved for NHL; other comparators were either more expensive and less effective than PP or SP with pegfilgrastim or had lower costs but higher ICERs (relative to SP with pegfilgrastim) than PP with pegfilgrastim. Results of the DSA for breast cancer and NHL comparing PP and SP with pegfilgrastim indicate that the model results were most sensitive to the cycle 1 risk of FN, the proportion of FN events requiring hospitalization, the relative risk of FN in cycles ≥2 versus cycle 1, no history of FN, and the mortality hazard ratio for RDI (<90% vs ≥90% [for NHL]). In the PSAs for stage II breast cancer and NHL, the probabilities that PP with pegfilgrastim was cost effective or dominant versus all other prophylaxis strategies at a €30,000/QALY willingness-to-pay threshold were 52% (other strategies ≤24%) and 58% (other strategies ≤24%), respectively. From a Belgian payer perspective, PP with pegfilgrastim appears cost effective compared to other prophylaxis strategies in patients with stage II breast cancer or NHL at a €30,000/QALY threshold.

A Randomized Controlled Trial of Mindfulness Meditation for Chronic Insomnia

PubMed Central

Ong, Jason C.; Manber, Rachel; Segal, Zindel; Xia, Yinglin; Shapiro, Shauna; Wyatt, James K.

2014-01-01

Study Objectives: To evaluate the efficacy of mindfulness meditation for the treatment of chronic insomnia. Design: Three-arm, single-site, randomized controlled trial. Setting: Academic medical center. Participants: Fifty-four adults with chronic insomnia. Interventions: Participants were randomized to either mindfulness-based stress reduction (MBSR), mindfulness-based therapy for insomnia (MBTI), or an eight-week self-monitoring (SM) condition. Measurements and Results: Patient-reported outcome measures were total wake time (TWT) from sleep diaries, the pre-sleep arousal scale (PSAS), measuring a prominent waking correlate of insomnia, and the Insomnia Severity Index (ISI) to determine remission and response as clinical endpoints. Objective sleep measures were derived from laboratory polysomnography and wrist actigraphy. Linear mixed models showed that those receiving a meditation-based intervention (MBSR or MBTI) had significantly greater reductions on TWT minutes (43.75 vs 1.09), PSAS (7.13 vs 0.16), and ISI (4.56 vs 0.06) from baseline-to-post compared to SM. Post hoc analyses revealed that each intervention was superior to SM on each of the patient-reported measures, but no significant differences were found when comparing MBSR to MBTI from baseline-to-post. From baseline to 6-month follow-up, MBTI had greater reductions in ISI scores than MBSR (P < 0.05), with the largest difference occurring at the 3-month follow-up. Remission and response rates in MBTI and MBSR were sustained from post-treatment through follow-up, with MBTI showing the highest rates of treatment remission (50%) and response (78.6%) at the 6-month follow-up. Conclusions: Mindfulness meditation appears to be a viable treatment option for adults with chronic insomnia and could provide an alternative to traditional treatments for insomnia. Trial Registration: Mindfulness-Based Approaches to Insomnia: clinicaltrials.gov, identifier: NCT00768781 Citation: Ong JC, Manber R, Segal Z, Xia Y, Shapiro S, Wyatt JK. A randomized controlled trial of mindfulness meditation for chronic insomnia. SLEEP 2014;37(9):1553-1563. PMID:25142566

The effect of sampling rate and anti-aliasing filters on high-frequency response spectra

USGS Publications Warehouse

Boore, David M.; Goulet, Christine

2013-01-01

The most commonly used intensity measure in ground-motion prediction equations is the pseudo-absolute response spectral acceleration (PSA), for response periods from 0.01 to 10 s (or frequencies from 0.1 to 100 Hz). PSAs are often derived from recorded ground motions, and these motions are usually filtered to remove high and low frequencies before the PSAs are computed. In this article we are only concerned with the removal of high frequencies. In modern digital recordings, this filtering corresponds at least to an anti-aliasing filter applied before conversion to digital values. Additional high-cut filtering is sometimes applied both to digital and to analog records to reduce high-frequency noise. Potential errors on the short-period (high-frequency) response spectral values are expected if the true ground motion has significant energy at frequencies above that of the anti-aliasing filter. This is especially important for areas where the instrumental sample rate and the associated anti-aliasing filter corner frequency (above which significant energy in the time series is removed) are low relative to the frequencies contained in the true ground motions. A ground-motion simulation study was conducted to investigate these effects and to develop guidance for defining the usable bandwidth for high-frequency PSA. The primary conclusion is that if the ratio of the maximum Fourier acceleration spectrum (FAS) to the FAS at a frequency fsaa corresponding to the start of the anti-aliasing filter is more than about 10, then PSA for frequencies above fsaa should be little affected by the recording process, because the ground-motion frequencies that control the response spectra will be less than fsaa . A second topic of this article concerns the resampling of the digital acceleration time series to a higher sample rate often used in the computation of short-period PSA. We confirm previous findings that sinc-function interpolation is preferred to the standard practice of using linear time interpolation for the resamplin

Choking Lake Winnipeg

NASA Astrophysics Data System (ADS)

Byrne, J. M.; Little, L. J.; Dodgson, K. A.; MacDonald, R. J.; Graham, J.

2009-12-01

The problems of waterway eutrophication and coastal zone hypoxia are reaching epidemic proportions. Fresh water and coastal marine environments around the world are suffering unprecedented pollution loadings. We are developing an education program to address the dramatic need for public, community and K-12 education about the harsh impacts of elevated nutrient loads on fresh and marine water environments. The Lake Winnipeg watershed is adopted as the poster child of fresh water eutrophication in western North America. The watershed, one of the largest on the continent, is in rapid decline due to pollution, population pressures and water diversion. A concerted education program is needed to change personal and society actions that negatively impact the Winnipeg watershed; and the confluence of the watershed - Lake Winnipeg. But the education program goes beyond Lake Winnipeg. Negative impacts of nutrient loads are adversely affecting environments right to the oceans. Major dead zones that are expanding on our continental shelves due to nutrient overloading threaten to coalesce into extensive regions of marine life die-off. This presentation outlines the documentary education production process under development. We are building a series of Public Service Announcements (PSAs) for national television networks. The PSAs will direct educators, stakeholders and citizens to an associated website with educational video clips detailing the issues of eutrophication and hypoxia. The video clips or webisodes, present interviews with leading scientists. The discussions address the causes of the problems, and presents workable solutions to nutrient overloads from a variety of sources. The webisodes are accompanied by notes and advice to teachers on ways and means to use the webisodes in classrooms. The project is fully funed by a group of Canadian Community Foundations, with the understanding the work wil be available free to educators anywhere in the world. Our education program will enhance public awareness, beg scrutiny of the issues and promote informed discussion about possible solutions. This education program will enlighten all parties and facilitate personal and societal actions to reverse and control pollution of our rivers, lakes and oceans.

Cost-effectiveness analysis of allopurinol versus febuxostat in chronic gout patients: a U.S. payer perspective.

PubMed

Gandhi, Pranav K; Gentry, William M; Ma, Qinli; Bottorff, Michael B

2015-02-01

Gout is a chronic inflammatory condition associated with poor urate metabolism. Xanthine oxidase inhibitors such as allopurinol and febuxostat are recommended to reduce uric acid levels and to prevent gout attacks in adult patients. Under budget-driven constraints, health care payers are faced with the broader challenge of assessing the economic value of these agents for formulary placement. However, the economic value of allopurinol versus febuxostat has not be assessed in patients with gout over a 5-year time period in the United States. To evaluate the cost-effectiveness of allopurinol versus febuxostat in adult patients with gout over a 5-year time period from a U.S. health care payer's perspective. A Markov model was developed to compare the total direct costs and success of serum uric acid (sUA) level reduction associated with allopurinol and febuxostat. Treatment success was defined as patient achievement of a sUA level less than  6 mg/dL (0.36 mmol/L) at 6 months. Event probabilities were based on published phase III randomized clinical trials and included long-term sequelae from open-label extension studies. A hypothetical cohort of 1,000 adult gout patients with sUA levels of ≥ 8 mg/dL (0.48 mmol/L) who had received either allopurinol 300 mg or febuxostat 80 mg at model entry transitioned among the 4 health states defined by treatment success, treatment failure and switch, treatment dropout, and death. The length of each Markov cycle was 6 months. Costs were gathered from the RED BOOK, Medicare fee schedules, Healthcare Cost and Utilization Project's Nationwide Inpatient Sample, and for a limited number of inputs, expert consultation. Direct costs included treatment drug costs, costs for prophylaxis drugs, diagnostic laboratory tests, and the treatment and management of acute gout flare. Resource utilization was based on clinical evidence and expert consultation. All costs were inflated to 2014 U.S. dollars and were discounted at 3% in the base case. One-way sensitivity analysis and probabilistic sensitivity analyses (PSAs) were performed to assess the robustness of the results. The total per patient cost incurred over 5 years was $50,295 for febuxostat and $48,413 for allopurinol, with an incremental total cost of $1,882. The expected percentage of treatment success during the 5-year period was 72 for febuxostat and 42 for allopurinol, resulting in an incremental percentage of treatment success of 30. The estimated incremental cost-effectiveness ratio for febuxostat compared with allopurinol was $6,322 per treatment success over a 5-year time period. The one-way sensitivity analysis indicated that the results were sensitive to probability of treatment success for allopurinol, probability of treatment dropouts for both allopurinol and febuxostat, and the probability of failure and switch to allopurinol. PSAs demonstrated that at a willingness-to-pay threshold of $50,000 per treatment success, febuxostat was cost-effective compared with allopurinol. Febuxostat was found to be a cost-effective option compared with allopurinol based on a U.S. payer perspective.

A Biopsychological Model of Anti-drug PSA Processing: Developing Effective Persuasive Messages.

PubMed

Hohman, Zachary P; Keene, Justin Robert; Harris, Breanna N; Niedbala, Elizabeth M; Berke, Collin K

2017-11-01

For the current study, we developed and tested a biopsychological model to combine research on psychological tension, the Limited Capacity Model of Motivated Mediated Message Processing, and the endocrine system to predict and understand how people process anti-drug PSAs. We predicted that co-presentation of pleasant and unpleasant information, vs. solely pleasant or unpleasant, will trigger evaluative tension about the target behavior in persuasive messages and result in a biological response (increase in cortisol, alpha amylase, and heart rate). In experiment 1, we assessed the impact of co-presentation of pleasant and unpleasant information in persuasive messages on evaluative tension (conceptualized as attitude ambivalence), in experiment 2, we explored the impact of co-presentation on endocrine system responses (salivary cortisol and alpha amylase), and in experiment 3, we assessed the impact of co-presentation on heart rate. Across all experiments, we demonstrated that co-presentation of pleasant and unpleasant information, vs. solely pleasant or unpleasant, in persuasive communications leads to increases in attitude ambivalence, salivary cortisol, salivary alpha amylase, and heart rate. Taken together, the results support the initial paths of our biopsychological model of persuasive message processing and indicate that including both pleasant and unpleasant information in a message impacts the viewer. We predict that increases in evaluative tension and biological responses will aid in memory and cognitive processing of the message. However, future research is needed to test that hypothesis.

Multifarious applications of atomic force microscopy in forensic science investigations.

PubMed

Pandey, Gaurav; Tharmavaram, Maithri; Rawtani, Deepak; Kumar, Sumit; Agrawal, Y

2017-04-01

Forensic science is a wide field comprising of several subspecialties and uses methods derived from natural sciences for finding criminals and other evidence valid in a legal court. A relatively new area; Nano-forensics brings a new era of investigation in forensic science in which instantaneous results can be produced that determine various agents such as explosive gasses, biological agents and residues in different crime scenes and terrorist activity investigations. This can be achieved by applying Nanotechnology and its associated characterization techniques in forensic sciences. Several characterization techniques exist in Nanotechnology and nano-analysis is one such technique that is used in forensic science which includes Electron microscopes (EM) like Transmission (TEM) and Scanning (SEM), Raman microscopy (Micro -Raman) and Scanning Probe Microscopes (SPMs) like Atomic Force Microscope (AFM). Atomic force microscopy enables surface characterization of different materials by examining their morphology and mechanical properties. Materials that are immeasurable such as hair, body fluids, textile fibers, documents, polymers, pressure sensitive adhesives (PSAs), etc. are often encountered during forensic investigations. This review article will mainly focus on the use of AFM in the examination of different evidence such as blood stains, forged documents, human hair samples, ammunitions, explosives, and other such applications in the field of Forensic Science. Copyright © 2017 Elsevier B.V. All rights reserved.

Hallucinations in schizophrenia and Parkinson's disease: an analysis of sensory modalities involved and the repercussion on patients.

PubMed

Llorca, P M; Pereira, B; Jardri, R; Chereau-Boudet, I; Brousse, G; Misdrahi, D; Fénelon, G; Tronche, A-M; Schwan, R; Lançon, C; Marques, A; Ulla, M; Derost, P; Debilly, B; Durif, F; de Chazeron, I

2016-12-01

Hallucinations have been described in various clinical populations, but they are neither disorder nor disease specific. In schizophrenia patients, hallucinations are hallmark symptoms and auditory ones are described as the more frequent. In Parkinson's disease, the descriptions of hallucination modalities are sparse, but the hallucinations do tend to have less negative consequences. Our study aims to explore the phenomenology of hallucinations in both hallucinating schizophrenia patients and Parkinson's disease patients using the Psycho-Sensory hAllucinations Scale (PSAS). The main objective is to describe the phenomena of these clinical symptoms in those two specific populations. Each hallucinatory sensory modality significantly differed between Parkinson's disease and schizophrenia patients. Auditory, olfactory/gustatory and cœnesthetic hallucinations were more frequent in schizophrenia than visual hallucinations. The guardian angel item, usually not explored in schizophrenia, was described by 46% of these patients. The combination of auditory and visual hallucinations was the most frequent for both Parkinson's disease and schizophrenia. The repercussion index summing characteristics of each hallucination (frequency, duration, negative aspects, conviction, impact, control and sound intensity) was always higher for schizophrenia. A broader view including widespread characteristics and interdisciplinary works must be encouraged to better understand the complexity of the process involved in hallucinations.

Hallucinations in schizophrenia and Parkinson’s disease: an analysis of sensory modalities involved and the repercussion on patients

PubMed Central

Llorca, P. M.; Pereira, B.; Jardri, R.; Chereau-Boudet, I.; Brousse, G.; Misdrahi, D.; Fénelon, G.; Tronche, A.-M.; Schwan, R.; Lançon, C.; Marques, A.; Ulla, M.; Derost, P.; Debilly, B.; Durif, F.; de Chazeron, I.

2016-01-01

Hallucinations have been described in various clinical populations, but they are neither disorder nor disease specific. In schizophrenia patients, hallucinations are hallmark symptoms and auditory ones are described as the more frequent. In Parkinson’s disease, the descriptions of hallucination modalities are sparse, but the hallucinations do tend to have less negative consequences. Our study aims to explore the phenomenology of hallucinations in both hallucinating schizophrenia patients and Parkinson’s disease patients using the Psycho-Sensory hAllucinations Scale (PSAS). The main objective is to describe the phenomena of these clinical symptoms in those two specific populations. Each hallucinatory sensory modality significantly differed between Parkinson’s disease and schizophrenia patients. Auditory, olfactory/gustatory and cœnesthetic hallucinations were more frequent in schizophrenia than visual hallucinations. The guardian angel item, usually not explored in schizophrenia, was described by 46% of these patients. The combination of auditory and visual hallucinations was the most frequent for both Parkinson’s disease and schizophrenia. The repercussion index summing characteristics of each hallucination (frequency, duration, negative aspects, conviction, impact, control and sound intensity) was always higher for schizophrenia. A broader view including widespread characteristics and interdisciplinary works must be encouraged to better understand the complexity of the process involved in hallucinations. PMID:27905557

Acrylic Triblock Copolymers Incorporating Isosorbide for Pressure Sensitive Adhesives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gallagher, James J.; Hillmyer, Marc A.; Reineke, Theresa M.

A new monomer acetylated acrylic isosorbide (AAI) was prepared in two steps using common reagents without the need for column chromatography. Free radical polymerization of AAI afforded poly(acetylated acrylic isosorbide) (PAAI), which exhibited a glass transition temperature (Tg) = 95 °C and good thermal stability (Td, 5% weight loss; N2 = 331 °C, air = 291 °C). A series of ABA triblock copolymers with either poly(n-butyl acrylate) (PnBA) or poly(2-ethylhexyl acrylate) (PEHA) as the low Tg midblocks and PAAI as the high Tg end blocks were prepared using Reversible Addition–Fragmentation chain Transfer (RAFT) polymerization. The triblock copolymers ranging from 8–24more » wt % PAAI were evaluated as pressure sensitive adhesives by 180° peel, loop tack, and static shear testing. While the PAAI-PEHA-PAAI series exhibited poor adhesive qualities, the PAAI-PnBA-PAAI series of triblock copolymers demonstrated peel forces up to 2.9 N cm–1, tack forces up to 3.2 N cm–1, and no shear failure up to 10000 min. Dynamic mechanical analysis indicated that PAAI-PEHA-PAAI lacked the dissipative qualities needed to form an adhesive bond with the substrate, while the PAAI-PnBA-PAAI series exhibited a dynamic mechanical response consistent with related high performing PSAs.« less

Lack of Resilience Is Related to Stress-Related Sleep Reactivity, Hyperarousal, and Emotion Dysregulation in Insomnia Disorder

PubMed Central

Palagini, Laura; Moretto, Umberto; Novi, Martina; Masci, Isabella; Caruso, Danila; Drake, Christopher L.; Riemann, Dieter

2018-01-01

Study Objectives: According to the diathesis-stress model of insomnia, insomnia may develop in vulnerable individuals in response to stress. Resilience is a psychobiological factor that determines an individual's capacity to adapt successfully to stressful events and low resilience increases vulnerability for development of mental disorders. The aim was to explore resilience in subjects with insomnia and its relationship with the factors that contribute to its development and perpetuation. Methods: The study consisted of 58 subjects with Insomnia Disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition and 38 good sleepers. Resilience Scale for Adults (RSA), Ford Insomnia Response to Stress Test (FIRST), Pre-sleep Arousal Scale (PSAS), and Difficulties in Emotion Regulation Scale (DERS) were administered while taking into account psychiatric symptoms. Differences in means between groups were assessed using t test or Mann-Whitney U/Wilcoxon test. Linear/multivariable regression analyses and mediation analyses were performed. Results: Subjects with insomnia (24 females, mean age 49 ± 2.1 years) had lower RSA and higher FIRST, DERS, and PSAS scores than good sleepers (22 females, mean age 47.2 ± 1.2 years). After controlling for anxiety/depressive symptoms, low resilience correlated with high stress-related sleep reactivity (P = .004), pre-sleep cognitive hyperarousal (P = .01) and emotion dysregulation (P = .01). Emotion dysregulation mediated the relationship between low resilience and cognitive hyperarousal (Z = 2.06, P = .03). Conclusions: Subjects with insomnia showed low resilience, which was related to high stress-related sleep reactivity, emotional dysregulation, and hyperarousal. If resilience helps to minimize the extent of pathogenesis in the developmental process, an early identification of vulnerable candidates should be useful for preventing insomnia development and maintenance. Commentary: A commentary on this article appears in this issue on page 709. Citation: Palagini L, Moretto U, Novi M, Masci I, Caruso D, Drake CL, Riemann D. Lack of resilience is related to stress-related sleep reactivity, hyperarousal, and emotion dysregulation in insomnia disorder. J Clin Sleep Med. 2018;14(5):759–766. PMID:29734989

Development and psychometric evaluation of the Premarital Sexual Behavior Assessment Scale for Young Women (PSAS-YW): an exploratory mixed method study.

PubMed

Rahmani, Azam; Merghati-Khoei, Effat; Moghadam-Banaem, Lida; Hajizadeh, Ebrahim; Hamdieh, Mostafa; Montazeri, Ali

2014-06-13

Premarital sexual behaviors are important issue for women's health. The present study was designed to develop and examine the psychometric properties of a scale in order to identify young women who are at greater risk of premarital sexual behavior. This was an exploratory mixed method investigation. Indeed, the study was conducted in two phases. In the first phase, qualitative methods (focus group discussion and individual interview) were applied to generate items and develop the questionnaire. In the second phase, psychometric properties (validity and reliability) of the questionnaire were assessed. In the first phase an item pool containing 53 statements related to premarital sexual behavior was generated. In the second phase item reduction was applied and the final version of the questionnaire containing 26 items was developed. The psychometric properties of this final version were assessed and the results showed that the instrument has a good structure, and reliability. The results from exploratory factory analysis indicated a 5-factor solution for the instrument that jointly accounted for the 57.4% of variance observed. The Cronbach's alpha coefficient for the instrument was found to be 0.87. This study provided a valid and reliable scale to identify premarital sexual behavior in young women. Assessment of premarital sexual behavior might help to improve women's sexual abstinence.

Development and psychometric evaluation of the Premarital Sexual Behavior Assessment Scale for Young Women (PSAS-YW): an exploratory mixed method study

PubMed Central

2014-01-01

Background Premarital sexual behaviors are important issue for women’s health. The present study was designed to develop and examine the psychometric properties of a scale in order to identify young women who are at greater risk of premarital sexual behavior. Method This was an exploratory mixed method investigation. Indeed, the study was conducted in two phases. In the first phase, qualitative methods (focus group discussion and individual interview) were applied to generate items and develop the questionnaire. In the second phase, psychometric properties (validity and reliability) of the questionnaire were assessed. Results In the first phase an item pool containing 53 statements related to premarital sexual behavior was generated. In the second phase item reduction was applied and the final version of the questionnaire containing 26 items was developed. The psychometric properties of this final version were assessed and the results showed that the instrument has a good structure, and reliability. The results from exploratory factory analysis indicated a 5-factor solution for the instrument that jointly accounted for the 57.4% of variance observed. The Cronbach’s alpha coefficient for the instrument was found to be 0.87. Conclusion This study provided a valid and reliable scale to identify premarital sexual behavior in young women. Assessment of premarital sexual behavior might help to improve women’s sexual abstinence. PMID:24924696

Authenticity in Obesity Public Service Announcements: Influence of Spokesperson Type, Viewer Weight, and Source Credibility on Diet, Exercise, Information Seeking, and Electronic Word-of-Mouth Intentions.

PubMed

Phua, Joe; Tinkham, Spencer

2016-01-01

This study examined the joint influence of spokesperson type in obesity public service announcements (PSAs) and viewer weight on diet intention, exercise intention, information seeking, and electronic word-of-mouth (eWoM) intention. Results of a 2 (spokesperson type: real person vs. actor) × 2 (viewer weight: overweight vs. non-overweight) between-subjects experiment indicated that overweight viewers who saw the PSA featuring the real person had the highest diet intention, exercise intention, information seeking, and eWoM intention. Parasocial interaction was also found to mediate the relationships between spokesperson type/viewer weight and two of the dependent variables: diet intention and exercise intention. In addition, viewers who saw the PSA featuring the real person rated the spokesperson as significantly higher on source credibility (trustworthiness, competence, and goodwill) than those who saw the PSA featuring the actor.

Alcohol counter-advertising and the media. A review of recent research.

PubMed

Agostinelli, Gina; Grube, Joel W

2002-01-01

Counter-advertising commonly is used to balance the effects that alcohol advertising may have on alcohol consumption and alcohol-related problems. Such measures can take the form of print or broadcast advertisements (e.g., public service announcements [PSAs]) as well as product warning labels. The effectiveness of both types of counter-advertising is reviewed using the Elaboration Likelihood Model as a theoretical framework. For print and broadcast counter-advertisements, such factors as their emotional appeal and the credibility of the source, as well as audience factors, can influence their effectiveness. Further, brewer-sponsored counter-advertisements are evaluated and received differently than are the more conventional PSA counter-advertisements. For warning labels, both the content and design of the label influence their effectiveness, as do audience factors. The effectiveness of those labels is evaluated in terms of the extent to which they impact cognitive and affective processes as well as drinking behavior.

Investigations on the viscoelastic performance of pressure sensitive adhesives in drug-in-adhesive type transdermal films.

PubMed

Wolff, Hans-Michael; Irsan; Dodou, Kalliopi

2014-08-01

We aimed to investigate the effect of solubility parameter and drug concentration on the rheological behaviour of drug-in-adhesive films intended for transdermal application. Films were prepared over a range of drug concentrations (5%, 10% and 20% w/w) using ibuprofen, benzoic acid, nicotinic acid and lidocaine as model drugs in acrylic (Duro-Tak 87-4287 and Duro-Tak 87900A) or silicone (Bio-PSA 7-4301 and Bio-PSA 7-4302) pressure sensitive adhesives (PSAs). Saturation status of films was determined using light microscopy. Viscoelastic parameters were measured in rheology tests at 32°C. Subsaturated films had lower viscoelastic moduli whereas saturated films had higher moduli than the placebo films and/or a concentration-dependent increase in their modulus. Saturation concentration of each drug in the films was reflected by decreasing/increasing viscoelastic patterns. The viscoelastic windows (VWs) of the adhesive and drug-in-adhesive films clearly depicted the effect of solubility parameter differences, molar concentration of drug in the adhesive film and differences in PSA chemistry. Drug solubility parameters and molar drug concentrations have an impact on rheological patterns and thus on the adhesive performance of tested pressure sensitive adhesives intended for use in transdermal drug delivery systems. Use of the Flory equation in its limiting form was appropriate to predict drug solubility in the tested formulations.

Problems with numerical techniques: Application to mid-loop operation transients

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bryce, W.M.; Lillington, J.N.

1997-07-01

There has been an increasing need to consider accidents at shutdown which have been shown in some PSAs to provide a significant contribution to overall risk. In the UK experience has been gained at three levels: (1) Assessment of codes against experiments; (2) Plant studies specifically for Sizewell B; and (3) Detailed review of modelling to support the plant studies for Sizewell B. The work has largely been carried out using various versions of RELAP5 and SCDAP/RELAP5. The paper details some of the problems that have needed to be addressed. It is believed by the authors that these kinds ofmore » problems are probably generic to most of the present generation system thermal-hydraulic codes for the conditions present in mid-loop transients. Thus as far as possible these problems and solutions are proposed in generic terms. The areas addressed include: condensables at low pressure, poor time step calculation detection, water packing, inadequate physical modelling, numerical heat transfer and mass errors. In general single code modifications have been proposed to solve the problems. These have been very much concerned with means of improving existing models rather than by formulating a completely new approach. They have been produced after a particular problem has arisen. Thus, and this has been borne out in practice, the danger is that when new transients are attempted, new problems arise which then also require patching.« less

The Effect of Public Service Advertising on Cardiovascular Disease in Korea.

PubMed

Jang, Juhyun; Na, Baeg Ju; Lee, Moo-Sik; Seo, Soonryu; Sung, Changhyun; Kim, Hyun Joo; Lee, Jin Yong

2016-08-01

Public Service Advertising (PSA) is a public interest message disseminated in the form of an advertisement communication and its main purpose is to promote public behavioral changes regarding a social issue. Korea Centers for Disease Control and Prevention (KCDC) has been delivering PSA by various media. However, the effect of PSAs has never been evaluated. The purpose of this study was to estimate the effects of broadcasted PSA produced by KCDC on cardiovascular disease (CVD). One thousand adult participants throughout 15 provinces in Korea were chosen through the quota sampling method in 2012. A face-to-face research survey with 13 questions was conducted using a Computer Assisted Personal Interview (CAPI) system. Previous exposure to the PSA message, understanding, and behavioral intention to change was assessed. After watching the PSA, about 75% of participants answered that they could understand the contents well and 70% had willingness to change their behaviors associated with CVD. However, only 24% of participants answered they watched the PSA during the past year. The PSA had positive effects on increasing the level of understanding and intention to change behaviors regarding CVD. However, the level of exposure was low. KCDC should make an effort to increase the public exposure level, which could be an important success factor regarding the PSA. In addition, KCDC should consider customized PSA for vulnerable people such as multi-cultural families, the disabled, and the elderly.

A role for synaptic and network plasticity in controlling epileptiform activity in CA1 in the kainic acid-lesioned rat hippocampus in vitro.

PubMed Central

Bernard, C; Wheal, H V

1996-01-01

1. Stimulation of the surviving afferents in the stratum radiatum of the CA1 area in kainic acid-lesioned hippocampal slices produced graded epileptiform activity, part of which (> 20%) involved the activation of N-methyl-D-aspartate (NMDA) receptors. There was also a failure of synaptic inhibition in this region. In this preparation, we have tested the effects of low-frequency stimulation (LFS; 1 Hz for 15 min) on synaptic responses and epileptiform activity. 2. LFS resulted in long-term depression (LTD) of excitatory synaptic potentials (EPSPs), long-term decrease of population spike amplitudes (PSAs) and EPSP-spike (E-S) potentiation. Evoked epileptiform activity was reduced but neurons had a higher probability of discharge. LTD could be reversed by subsequent tetanic stimulation whereas E-S dissociation remained unchanged. Synaptic and network responses could be saturated towards either potentiation or depression. However, E-S potentiation was maximal following the first conditioning stimulus. 3. NMDA receptor-mediated responses were pharmacologically isolated. LFS resulted in LTD of synaptic responses, long-term decrease of PSAs and E-S depression. These depressions could not be reversed by subsequent tetanic stimulation. alpha-Amino-3-hydroxy-5-methylisoxazolepropionic acid (AMPA) and NMDA receptor-mediated responses were then measured in isolation before and following conditioning stimuli. LFS was shown to simultaneously produce LTD of AMPA and NMDA receptor-mediated responses. E-S potentiation of the AMPA component and E-S depression of the NMDA component occurred coincidentally. 4. LTD of AMPA and NMDA receptor-mediated responses were shown to be NMDA dependent. In contrast, E-S potentiation and depression occurred even when NMDA receptors were pharmacologically blocked. 5. These findings indicate that synaptic responses could be modified bidirectionally in the CA1 area of kainic acid-lesioned rat hippocampus in an NMDA receptor-dependent manner. However, E-S dissociations were independent of the activation of NMDA receptors, hinting at mechanisms different from those of synaptic LTD. We suggest that changes in E-S coupling were caused by a modification of the firing threshold of the CA1 pyramidal neurons. Furthermore, the firing mechanisms controlling NMDA and AMPA receptor-mediated network activity appeared to be different. The possible use of LFS applied to the hippocampus as a clinical intervention to suppress epileptiform activity is discussed. PMID:8866357

[Observation on the clinical application effects of skin distractor on the treatment of scars].

PubMed

Gui, W L; Yang, E; Zhang, H S

2017-03-20

Objective: To explore clinical application effects of skin distractor on the treatment of scars and to observe effects of skin distractor with different pull speeds on different parts scars of human body. Methods: One hundred and four patients with scars, conforming to the study criteria, were hospitalized in our unit from January 2014 to June 2015. Patients were divided into 2 mm/d group and 4 mm/d group according to the random number table, with 52 patients in each group. After admission, skin distractors were pasted on scars in face and neck, trunk, and extremities of patients in 2 groups, with inner edges of pasteboards close to outside edges of longer sides of scars. Skin distractors in 2 mm/d group and 4 mm/d group were pulled to scars axis direction as speeds of 2 mm/d and 4 mm/d, respectively. Pull time equals values of pull speeds divided by width of scars. Scars were resected after finishing pulling. Immediately after scars resection, skin distractors were pasted again with inner edges of pasteboards close to outside edges of longer sides of incision and removed when stitches were taken out. Scars of patients were scored by Vancouver Scar Scale (VSS), and Patient and Observer Scar Assessment Scale (POSAS) was used to record scores of patient scar assessment scale (PSAS), observer scar assessment scale (OSAS) and overall scores of patients and observers of scars of patients before and one year after scars resection. Data were processed with χ (2) test, independent samples t test, paired samples t test, independent samples non-parametric rank-sum test and paired samples non-parametric rank-sum test. Results: (1) Scores of all scars of patients in 2 groups before scars resection were close (with t values from -1.384 to 0.622, P values above 0.05), obviously higher than those of one year post scars resection (with t values from 11.085 to 24.835, P values below 0.01). Scores of scars in face and neck, trunk and extremities in 2 groups before scars resection were close (with Z values from -1.651 to -0.035, t values from -1.549 to 0.219, P values above 0.05), significantly higher than those of one year post scar resection (with Z values from -2.992 to -2.555, t values from 8.739 to 19.076, P values below 0.01). (2) Scores of all scars of patients in 2 mm/d group of one year post scars resection were lower than those in 4 mm/d group (with t values from -2.583 to -2.018, P values below 0.05). PSAS scores of scars in face and neck and trunk in 2 mm/d group of one year post scars resection were lower than those in 4 mm/d group (with Z values respectively -2.385 and -2.198, P values below 0.05), other scores of scars in face and neck and trunk of patients in 2 groups of one year post scars resection were close (with Z values from -1.841 to -0.363, P values above 0.05). VSS scores, PSAS scores, OSAS scores, patients' overall scores, and observers' overall scores in 2 mm/d groups were (4.6±0.8), (28±4), (28±4), (4.7±0.7), (4.8±1.4) points, respectively, lower than those in 4 mm/d group[(5.2±0.8), (32±4), (31±6), (5.5±1.2), (5.5±1.0) points, respectively, with t values from -3.712 to -2.105, P <0.05 or P <0.01]. Conclusions: Skin distractor has better effects on the treatment of scars, and treatment effects of skin distractor in extremities pulled by 2 mm/d are better than those pulled by 4 mm/d.

A Cost-Utility Analysis of Lisdexamfetamine Versus Atomoxetine in the Treatment of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder and Inadequate Response to Methylphenidate.

PubMed

Zimovetz, Evelina A; Beard, Stephen M; Hodgkins, Paul; Bischof, Matthias; Mauskopf, Josephine A; Setyawan, Juliana

2016-10-01

An economic analysis from the perspective of the UK National Health Service (NHS) evaluated the cost effectiveness of lisdexamfetamine dimesylate (LDX) compared with atomoxetine in children and adolescents with attention-deficit/hyperactivity disorder who have had an inadequate response to methylphenidate. A 1-year decision-analytic model was constructed, with the health outcomes "response", "nonresponse", and "unable to tolerate". Clinical data were taken from a head-to-head, randomized controlled trial in inadequate responders to methylphenidate. Response to treatment was defined as a score of 1 (very much improved) or 2 (much improved) on the Clinical Global Impression-Improvement subscale. Tolerability was assessed by discontinuation rates owing to adverse events. Utility weights were identified via a systematic literature review. Healthcare resource use estimates were obtained via a survey of clinicians. Daily drug costs were derived from British National Formulary 2012 costs and mean doses reported in the trial. One-way and probabilistic sensitivity analyses (PSAs) were performed. The comparison of LDX with atomoxetine resulted in an estimate of an incremental cost-effectiveness ratio of £1802 per quality-adjusted life-year (QALY). The result was robust in a wide range of sensitivity analyses; results were most sensitive to changes in drug costs and efficacy. In the PSA, assuming a maximum willingness to pay of £20,000 per QALY, LDX versus atomoxetine had an 86 % probability of being cost effective. In 38 % of PSA runs, LDX was more effective and less costly than atomoxetine. From the perspective of the UK NHS, LDX provides a cost-effective treatment option for children and adolescents who are inadequate responders to methylphenidate.

Determination of a Testing Threshold for Lumbar Puncture in the Diagnosis of Subarachnoid Hemorrhage after a Negative Head Computed Tomography: A Decision Analysis.

PubMed

Taylor, Richard Andrew; Singh Gill, Harman; Marcolini, Evie G; Meyers, H Pendell; Faust, Jeremy Samuel; Newman, David H

2016-10-01

The objective was to determine the testing threshold for lumbar puncture (LP) in the evaluation of aneurysmal subarachnoid hemorrhage (SAH) after a negative head computed tomography (CT). As a secondary aim we sought to identify clinical variables that have the greatest impact on this threshold. A decision analytic model was developed to estimate the testing threshold for patients with normal neurologic findings, being evaluated for SAH, after a negative CT of the head. The testing threshold was calculated as the pretest probability of disease where the two strategies (LP or no LP) are balanced in terms of quality-adjusted life-years. Two-way and probabilistic sensitivity analyses (PSAs) were performed. For the base-case scenario the testing threshold for performing an LP after negative head CT was 4.3%. Results for the two-way sensitivity analyses demonstrated that the test threshold ranged from 1.9% to 15.6%, dominated by the uncertainty in the probability of death from initial missed SAH. In the PSA the mean testing threshold was 4.3% (95% confidence interval = 1.4% to 9.3%). Other significant variables in the model included probability of aneurysmal versus nonaneurysmal SAH after negative head CT, probability of long-term morbidity from initial missed SAH, and probability of renal failure from contrast-induced nephropathy. Our decision analysis results suggest a testing threshold for LP after negative CT to be approximately 4.3%, with a range of 1.4% to 9.3% on robust PSA. In light of these data, and considering the low probability of aneurysmal SAH after a negative CT, classical teaching and current guidelines addressing testing for SAH should be revisited. © 2016 by the Society for Academic Emergency Medicine.

Examining the Impact of Public Service Announcements on Help Seeking and Stigma: Results of a Randomized Controlled Trial.

PubMed

Corrigan, Patrick W; Powell, Karina J; Al-Khouja, Maya A

2015-11-01

Health communication campaigns often seek to diminish stigma and promote care seeking, with public service announcements (PSAs) frequently prominent in these campaigns. One example is the Australian-based beyondblue campaign. As an alternative approach, campaigns may seek to reduce stigma by promoting stories of recovery. Participants completed measures of stigmatizing and empowering attitudes at pre-, post-, and 72-hour follow-up after being randomized to a PSA recovery-oriented video, treatable disease-oriented video (beyondblue), or control. When exposed to the recovery-oriented PSA, participants showed significant reduction in stigmatizing attitudes from pre- to posttest than beyondblue or the control group with the emergence of nonsignificant trends identified at follow-up. Findings suggest a recovery-oriented video leads to better change on measures of stigma and affirming attitudes than beyondblue. Despite the aforementioned findings, results failed to show either the recovery or beyondblue videos had a significant impact on intent to seek treatment.

The Effect of Public Service Advertising on Cardiovascular Disease in Korea

PubMed Central

JANG, Juhyun; NA, Baeg Ju; LEE, Moo-Sik; SEO, Soonryu; SUNG, Changhyun; KIM, Hyun Joo; LEE, Jin Yong

2016-01-01

Background: Public Service Advertising (PSA) is a public interest message disseminated in the form of an advertisement communication and its main purpose is to promote public behavioral changes regarding a social issue. Korea Centers for Disease Control and Prevention (KCDC) has been delivering PSA by various media. However, the effect of PSAs has never been evaluated. The purpose of this study was to estimate the effects of broadcasted PSA produced by KCDC on cardiovascular disease (CVD). Methods: One thousand adult participants throughout 15 provinces in Korea were chosen through the quota sampling method in 2012. A face-to-face research survey with 13 questions was conducted using a Computer Assisted Personal Interview (CAPI) system. Previous exposure to the PSA message, understanding, and behavioral intention to change was assessed. Results: After watching the PSA, about 75% of participants answered that they could understand the contents well and 70% had willingness to change their behaviors associated with CVD. However, only 24% of participants answered they watched the PSA during the past year. Conclusion: The PSA had positive effects on increasing the level of understanding and intention to change behaviors regarding CVD. However, the level of exposure was low. KCDC should make an effort to increase the public exposure level, which could be an important success factor regarding the PSA. In addition, KCDC should consider customized PSA for vulnerable people such as multi-cultural families, the disabled, and the elderly. PMID:27928529

Content matters: neuroimaging investigation of brain and behavioral impact of televised anti-tobacco public service announcements

PubMed Central

Wang, An-Li; Ruparel, Kosha; Loughead, James W.; Strasser, Andrew A.; Blady, Shira J.; Lynch, Kevin G.; Romer, Dan; Cappella, Joseph N.; Lerman, Caryn; Langleben, Daniel D.

2013-01-01

Public service announcements (PSAs) are televised ads that are a key component of public health campaigns against smoking. Understanding the neurophysiological correlates of anti-tobacco ads is an important step towards novel objective methods of their evaluation and design. In the present study, we used Functional Magnetic Resonance Imaging (fMRI) to investigate the brain and behavioral effects of the interaction between content (“argument strength”) and format (“message sensation value”) of anti-smoking ads in human. Seventy-one non-treatment seeking smokers viewed a sequence of sixteen high or 16 low argument strength ads during a fMRI scan. Dependent variables were brain fMRI signal, the immediate recall of the ads, immediate change in Intentions to Quit Smoking and the urine levels of a major nicotine metabolite cotinine at a one-month follow-up. Whole brain ANOVA revealed that argument strength and message sensation value interacted in the inferior frontal, inferior parietal and fusiform gyri, the precuneus and the dorsomedial prefrontal cortex (dMPFC). Regression analysis showed that the activation in the dMPFC predicted lower cotinine levels a month later. These results characterize the key brain regions engaged in the processing of persuasive communications and suggest that brain fMRI response to anti-smoking ads could predict subsequent smoking severity in non-treatment seeking smokers. Our findings demonstrate the importance of the quality of ad content for objective ad outcomes and suggest that fMRI investigation may aid the pre-release evaluation of televised public health announcements. PMID:23616548

Lifetime Stress Cumulatively Programs Brain Transcriptome and Impedes Stroke Recovery: Benefit of Sensory Stimulation

PubMed Central

Zucchi, Fabíola C. R.; Yao, Youli; Ilnytskyy, Yaroslav; Robbins, Jerrah C.; Soltanpour, Nasrin; Kovalchuk, Igor; Kovalchuk, Olga; Metz, Gerlinde A. S.

2014-01-01

Prenatal stress (PS) represents a critical variable affecting lifetime health trajectories, metabolic and vascular functions. Beneficial experiences may attenuate the effects of PS and its programming of health outcomes in later life. Here we investigated in a rat model (1) if PS modulates recovery following cortical ischemia in adulthood; (2) if a second hit by adult stress (AS) exaggerates stress responses and ischemic damage; and (3) if tactile stimulation (TS) attenuates the cumulative effects of PS and AS. Prenatally stressed and non-stressed adult male rats underwent focal ischemic motor cortex lesion and were tested in skilled reaching and skilled walking tasks. Two groups of rats experienced recurrent restraint stress in adulthood and one of these groups also underwent daily TS therapy. Animals that experienced both PS and AS displayed the most severe motor disabilities after lesion. By contrast, TS promoted recovery from ischemic lesion and reduced hypothalamic-pituitary-adrenal axis activity. The data also showed that cumulative effects of adverse and beneficial lifespan experiences interact with disease outcomes and brain plasticity through the modulation of gene expression. Microarray analysis of the lesion motor cortex revealed that cumulative PS and AS interact with genes related to growth factors and transcription factors, which were not affected by PS or lesion alone. TS in PS+AS animals reverted these changes, suggesting a critical role for these factors in activity-dependent motor cortical reorganization after ischemic lesion. These findings suggest that beneficial experience later in life can moderate adverse consequences of early programming to improve cerebrovascular health. PMID:24651125

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

PubMed

Mikropoulos, Christos; Selkirk, Christina G Hutten; Saya, Sibel; Bancroft, Elizabeth; Vertosick, Emily; Dadaev, Tokhir; Brendler, Charles; Page, Elizabeth; Dias, Alexander; Evans, D Gareth; Rothwell, Jeanette; Maehle, Lovise; Axcrona, Karol; Richardson, Kate; Eccles, Diana; Jensen, Thomas; Osther, Palle J; van Asperen, Christi J; Vasen, Hans; Kiemeney, Lambertus A; Ringelberg, Janneke; Cybulski, Cezary; Wokolorczyk, Dominika; Hart, Rachel; Glover, Wayne; Lam, Jimmy; Taylor, Louise; Salinas, Monica; Feliubadaló, Lidia; Oldenburg, Rogier; Cremers, Ruben; Verhaegh, Gerald; van Zelst-Stams, Wendy A; Oosterwijk, Jan C; Cook, Jackie; Rosario, Derek J; Buys, Saundra S; Conner, Tom; Domchek, Susan; Powers, Jacquelyn; Ausems, Margreet Gem; Teixeira, Manuel R; Maia, Sofia; Izatt, Louise; Schmutzler, Rita; Rhiem, Kerstin; Foulkes, William D; Boshari, Talia; Davidson, Rosemarie; Ruijs, Marielle; Helderman-van den Enden, Apollonia Tjm; Andrews, Lesley; Walker, Lisa; Snape, Katie; Henderson, Alex; Jobson, Irene; Lindeman, Geoffrey J; Liljegren, Annelie; Harris, Marion; Adank, Muriel A; Kirk, Judy; Taylor, Amy; Susman, Rachel; Chen-Shtoyerman, Rakefet; Pachter, Nicholas; Spigelman, Allan; Side, Lucy; Zgajnar, Janez; Mora, Josefina; Brewer, Carole; Gadea, Neus; Brady, Angela F; Gallagher, David; van Os, Theo; Donaldson, Alan; Stefansdottir, Vigdis; Barwell, Julian; James, Paul A; Murphy, Declan; Friedman, Eitan; Nicolai, Nicola; Greenhalgh, Lynn; Obeid, Elias; Murthy, Vedang; Copakova, Lucia; McGrath, John; Teo, Soo-Hwang; Strom, Sara; Kast, Karin; Leongamornlert, Daniel A; Chamberlain, Anthony; Pope, Jenny; Newlin, Anna C; Aaronson, Neil; Ardern-Jones, Audrey; Bangma, Chris; Castro, Elena; Dearnaley, David; Eyfjord, Jorunn; Falconer, Alison; Foster, Christopher S; Gronberg, Henrik; Hamdy, Freddie C; Johannsson, Oskar; Khoo, Vincent; Lubinski, Jan; Grindedal, Eli Marie; McKinley, Joanne; Shackleton, Kylie; Mitra, Anita V; Moynihan, Clare; Rennert, Gad; Suri, Mohnish; Tricker, Karen; Moss, Sue; Kote-Jarai, Zsofia; Vickers, Andrew; Lilja, Hans; Helfand, Brian T; Eeles, Rosalind A

2018-01-01

Prostate-specific antigen (PSA) and PSA-velocity (PSAV) have been used to identify men at risk of prostate cancer (PrCa). The IMPACT study is evaluating PSA screening in men with a known genetic predisposition to PrCa due to BRCA1/2 mutations. This analysis evaluates the utility of PSA and PSAV for identifying PrCa and high-grade disease in this cohort. PSAV was calculated using logistic regression to determine if PSA or PSAV predicted the result of prostate biopsy (PB) in men with elevated PSA values. Cox regression was used to determine whether PSA or PSAV predicted PSA elevation in men with low PSAs. Interaction terms were included in the models to determine whether BRCA status influenced the predictiveness of PSA or PSAV. 1634 participants had ⩾3 PSA readings of whom 174 underwent PB and 45 PrCas diagnosed. In men with PSA >3.0 ng ml -l , PSAV was not significantly associated with presence of cancer or high-grade disease. PSAV did not add to PSA for predicting time to an elevated PSA. When comparing BRCA1/2 carriers to non-carriers, we found a significant interaction between BRCA status and last PSA before biopsy (P=0.031) and BRCA2 status and PSAV (P=0.024). However, PSAV was not predictive of biopsy outcome in BRCA2 carriers. PSA is more strongly predictive of PrCa in BRCA carriers than non-carriers. We did not find evidence that PSAV aids decision-making for BRCA carriers over absolute PSA value alone.

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition

PubMed Central

Mikropoulos, Christos; Selkirk, Christina G Hutten; Saya, Sibel; Bancroft, Elizabeth; Vertosick, Emily; Dadaev, Tokhir; Brendler, Charles; Page, Elizabeth; Dias, Alexander; Evans, D Gareth; Rothwell, Jeanette; Maehle, Lovise; Axcrona, Karol; Richardson, Kate; Eccles, Diana; Jensen, Thomas; Osther, Palle J; van Asperen, Christi J; Vasen, Hans; Kiemeney, Lambertus A; Ringelberg, Janneke; Cybulski, Cezary; Wokolorczyk, Dominika; Hart, Rachel; Glover, Wayne; Lam, Jimmy; Taylor, Louise; Salinas, Monica; Feliubadaló, Lidia; Oldenburg, Rogier; Cremers, Ruben; Verhaegh, Gerald; van Zelst-Stams, Wendy A; Oosterwijk, Jan C; Cook, Jackie; Rosario, Derek J; Buys, Saundra S; Conner, Tom; Domchek, Susan; Powers, Jacquelyn; Ausems, Margreet GEM; Teixeira, Manuel R; Maia, Sofia; Izatt, Louise; Schmutzler, Rita; Rhiem, Kerstin; Foulkes, William D; Boshari, Talia; Davidson, Rosemarie; Ruijs, Marielle; Helderman-van den Enden, Apollonia TJM; Andrews, Lesley; Walker, Lisa; Snape, Katie; Henderson, Alex; Jobson, Irene; Lindeman, Geoffrey J; Liljegren, Annelie; Harris, Marion; Adank, Muriel A; Kirk, Judy; Taylor, Amy; Susman, Rachel; Chen-Shtoyerman, Rakefet; Pachter, Nicholas; Spigelman, Allan; Side, Lucy; Zgajnar, Janez; Mora, Josefina; Brewer, Carole; Gadea, Neus; Brady, Angela F; Gallagher, David; van Os, Theo; Donaldson, Alan; Stefansdottir, Vigdis; Barwell, Julian; James, Paul A; Murphy, Declan; Friedman, Eitan; Nicolai, Nicola; Greenhalgh, Lynn; Obeid, Elias; Murthy, Vedang; Copakova, Lucia; McGrath, John; Teo, Soo-Hwang; Strom, Sara; Kast, Karin; Leongamornlert, Daniel A; Chamberlain, Anthony; Pope, Jenny; Newlin, Anna C; Aaronson, Neil; Ardern-Jones, Audrey; Bangma, Chris; Castro, Elena; Dearnaley, David; Eyfjord, Jorunn; Falconer, Alison; Foster, Christopher S; Gronberg, Henrik; Hamdy, Freddie C; Johannsson, Oskar; Khoo, Vincent; Lubinski, Jan; Grindedal, Eli Marie; McKinley, Joanne; Shackleton, Kylie; Mitra, Anita V; Moynihan, Clare; Rennert, Gad; Suri, Mohnish; Tricker, Karen; Moss, Sue; Kote-Jarai, Zsofia; Vickers, Andrew; Lilja, Hans; Helfand, Brian T; Eeles, Rosalind A

2018-01-01

Background: Prostate-specific antigen (PSA) and PSA-velocity (PSAV) have been used to identify men at risk of prostate cancer (PrCa). The IMPACT study is evaluating PSA screening in men with a known genetic predisposition to PrCa due to BRCA1/2 mutations. This analysis evaluates the utility of PSA and PSAV for identifying PrCa and high-grade disease in this cohort. Methods: PSAV was calculated using logistic regression to determine if PSA or PSAV predicted the result of prostate biopsy (PB) in men with elevated PSA values. Cox regression was used to determine whether PSA or PSAV predicted PSA elevation in men with low PSAs. Interaction terms were included in the models to determine whether BRCA status influenced the predictiveness of PSA or PSAV. Results: 1634 participants had ⩾3 PSA readings of whom 174 underwent PB and 45 PrCas diagnosed. In men with PSA >3.0 ng ml−l, PSAV was not significantly associated with presence of cancer or high-grade disease. PSAV did not add to PSA for predicting time to an elevated PSA. When comparing BRCA1/2 carriers to non-carriers, we found a significant interaction between BRCA status and last PSA before biopsy (P=0.031) and BRCA2 status and PSAV (P=0.024). However, PSAV was not predictive of biopsy outcome in BRCA2 carriers. Conclusions: PSA is more strongly predictive of PrCa in BRCA carriers than non-carriers. We did not find evidence that PSAV aids decision-making for BRCA carriers over absolute PSA value alone. PMID:29301143

Message sensation and cognition values: factors of competition or integration?

PubMed

Xu, Jie

2015-01-01

Using the Activation Model of Information Exposure and Elaboration Likelihood Model as theoretical frameworks, this study explored the effects of message sensation value (MSV) and message cognition value (MCV) of antismoking public service announcements (PSAs) on ad processing and evaluation among young adults, and the difference between high sensation seekers and low sensation seekers in their perceptions and responses toward ads with different levels of sensation and cognition value. A 2 (MSV: high vs. low) × 2 (MCV: high vs. low) × 2 (need for sensation: high vs. low) mixed experimental design was conducted. Two physiological measures including skin conductance and heart rate were examined. Findings of this study show that MSV was not a distraction but a facilitator of message persuasiveness. These findings contribute to the activation model. In addition, need for sensation moderated the interaction effect of MSV and MCV on ad processing. Low sensation seekers were more likely to experience the interaction between MSV and MCV than high sensation seekers. Several observations related to the findings and implications for antismoking message designs are elaborated. Limitations and directions for future research are also outlined.

Attitudes and Perceptions of Suicide and Suicide Prevention Messages for Asian Americans

PubMed Central

Thapa, Priyata; Sung, Yoonhee; Klingbeil, David A.; Lee, Chih-Yuan Steven; Klimes-Dougan, Bonnie

2015-01-01

Understanding the context of suicidal behaviors is critical for effective suicide prevention strategies. Although suicide is an important topic for Asian Americans, there is limited information about what Asian Americans’ attitudes are towards suicide and their perceptions about the effectiveness of prevention efforts. These questions are critical to examine to provide foundational knowledge for determining how best to intervene. In this study, Asian American (n = 87) and White (n = 87) participants completed self-report indexes on their knowledge of depression and suicide (e.g., estimates of suicide rates), coping attitudes (e.g., help-seeking) and suicide prevention attitudes (e.g., usefulness of PSAs). The results indicate that in comparison to Whites, Asian Americans perceived suicidal behavior to be more common, perceived a stronger link between depression and suicide, less frequently endorsed help-seeking strategies, and reported more concern or distress after viewing a suicide prevention PSA. These preliminary results also suggest the possibility of cultural differences in perceptions of suicide prevention messages. The implications of these findings are discussed with a focus on providing recommendations for exploring suicide prevention efforts for Asian Americans. PMID:26690227

Black youth's personal involvement in the HIV/AIDS issue: does the public service announcement still work?

PubMed

Keys, Truman R; Morant, Kesha M; Stroman, Carolyn A

2009-03-01

Recent public service announcements (PSAs) directed toward Black youth utilize various formats and appeals to stimulate a motivated cognitive process that engenders personal involvement in the HIV/AIDS issue. The Elaboration Likelihood Model (ELM) by Petty and Cacioppo argues that engagement with messages that consist of substantive content causes the audience member to critically analyze the message, which can produce awareness and attitude change. An efficient way to add emphasis to the message and seize the attention of the target audience is to insert the message into an entertainment context. Our study attempted to analyze the impact of the peripheral cue, character appeal, on audience members' attitude change in response to analyzing high- and low-involvement message content. A2 x 4 factorial design was used, with message involvement (high/low) and character appeal (White/Black and celebrity/noncelebrity) as independent variables. The findings showed that celebrity status is the salient factor, with source perception inducing attitude change as a main effect or in an interaction effect with high- and low message content.

Polarization Smoothing Generalized MUSIC Algorithm with Polarization Sensitive Array for Low Angle Estimation.

PubMed

Tan, Jun; Nie, Zaiping

2018-05-12

Direction of Arrival (DOA) estimation of low-altitude targets is difficult due to the multipath coherent interference from the ground reflection image of the targets, especially for very high frequency (VHF) radars, which have antennae that are severely restricted in terms of aperture and height. The polarization smoothing generalized multiple signal classification (MUSIC) algorithm, which combines polarization smoothing and generalized MUSIC algorithm for polarization sensitive arrays (PSAs), was proposed to solve this problem in this paper. Firstly, the polarization smoothing pre-processing was exploited to eliminate the coherence between the direct and the specular signals. Secondly, we constructed the generalized MUSIC algorithm for low angle estimation. Finally, based on the geometry information of the symmetry multipath model, the proposed algorithm was introduced to convert the two-dimensional searching into one-dimensional searching, thus reducing the computational burden. Numerical results were provided to verify the effectiveness of the proposed method, showing that the proposed algorithm has significantly improved angle estimation performance in the low-angle area compared with the available methods, especially when the grazing angle is near zero.

Cost-effectiveness Analysis for Apixaban in the Acute Treatment and Prevention of Venous Thromboembolism in the Netherlands.

PubMed

de Jong, Lisa A; Dvortsin, Evgeni; Janssen, Kristel J; Postma, Maarten J

2017-02-01

Low-molecular weight heparin (LMWH) followed by vitamin K antagonists (VKAs) are the current standard treatment of acute venous thromboembolism (VTE) and prevention of recurrent VTE. The direct oral anticoagulant apixaban was recently found noninferior in efficacy and superior in preventing major bleeding compared with LMWH/VKAs in the AMPLIFY (Apixaban for the Initial Management of Pulmonary Embolism and Deep-Vein Thrombosis as First-Line Therapy) trial. The objective of this study was to calculate the cost-effectiveness of apixaban compared with LMWH/VKA in the treatment of acute VTE and prevention of recurrent VTE in the Netherlands. A Markov model was designed to simulate a cohort of 1,000 VTE patients receiving either apixaban or LMWH/VKA. Transition probabilities, costs, and utilities were obtained from the AMPLIFY trial and other literature. The incremental cost-effectiveness ratio (ICER) was calculated from the societal perspective; therefore, the model included both direct (inside and outside the health care sector) and indirect costs. In the univariate and probabilistic sensitivity analyses (PSAs) the robustness of the results was tested, and various additional scenario analyses were conducted. In the base-case analysis, apixaban saved €236 and 0.044 quality-adjusted life years (QALYs) and 0.039 LYs were gained compared with LMWH/VKA. In the univariate sensitivity analysis the model appeared to be robust. The results of 2,000 iterations in the PSA found that the probability of apixaban being cost-effective at a willingness-to-pay threshold of €20,000/QALY was 100% and cost-saving was 94%. The scenario of 18-month treatment duration was the only scenario not indicating cost-savings with an ICER of €425/QALY. In acute anticoagulation use apixaban was found to be cost-saving. A longer anticoagulation period (18 months) resulted in a higher difference in drug costs, indicating a higher ICER. The cost-effectiveness of long-term or life-long use should be examined in future research. Copyright © 2017 Elsevier HS Journals, Inc. All rights reserved.

Seven-Month Prostate-Specific Antigen Is Prognostic in Metastatic Hormone-Sensitive Prostate Cancer Treated With Androgen Deprivation With or Without Docetaxel

PubMed Central

Harshman, Lauren C.; Chen, Yu-Hui; Liu, Glenn; Carducci, Michael A.; Jarrard, David; Dreicer, Robert; Hahn, Noah; Garcia, Jorge A.; Hussain, Maha; Shevrin, Daniel; Eisenberger, Mario; Kohli, Manish; Plimack, Elizabeth R.; Cooney, Matthew; Vogelzang, Nicholas J.; Picus, Joel; Dipaola, Robert

2018-01-01

Purpose We evaluated the relationship between prostate-specific antigen (PSA) and overall survival in the context of a prospectively randomized clinical trial comparing androgen-deprivation therapy (ADT) plus docetaxel with ADT alone for initial metastatic hormone-sensitive prostate cancer. Methods We performed a landmark survival analysis at 7 months using the E3805 Chemohormonal Therapy Versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer (CHAARTED) database (ClinicalTrials.gov identifier: NCT00309985). Inclusion required at least 7 months of follow-up and PSA levels at 7 months from ADT initiation. We used the prognostic classifiers identified in a previously reported trial (Southwest Oncology Group 9346) of PSA ≤ 0.2, > 0.2 to 4, and > 4 ng/mL. Results Seven hundred nineteen of 790 patients were eligible for this subanalysis; 358 were treated with ADT plus docetaxel, and 361 were treated with ADT alone. Median follow-up time was 23.1 months. On multivariable analysis, achieving a 7-month PSA ≤ 0.2 ng/mL was more likely with docetaxel, low-volume disease, prior local therapy, and lower baseline PSAs (all P ≤ .01). Across all patients, median overall survival was significantly longer if 7-month PSA reached ≤ 0.2 ng/mL compared with > 4 ng/mL (median survival, 60.4 v 22.2 months, respectively; P < .001). On multivariable analysis, 7-month PSA ≤ 0.2 and low volume disease were prognostic of longer overall survival (all P < 0.01). The addition of docetaxel increased the likelihood of achieving a PSA ≤ 0.2 ng/mL at 7 months (45.3% v 28.8% of patients on ADT alone). Patients on ADT alone who achieved a 7-month PSA ≤ 0.2 ng/mL had the best survival and were more likely to have low-volume disease (56.7%). Conclusion PSA ≤ 0.2 ng/mL at 7 months is prognostic for longer overall survival with ADT for metastatic hormone-sensitive prostate cancer irrespective of docetaxel administration. Adding docetaxel increased the likelihood of a lower PSA and improved survival. PMID:29261442

A cost-effectiveness analysis of lisdexamfetamine dimesylate in the treatment of adults with attention-deficit/hyperactivity disorder in the UK.

PubMed

Zimovetz, Evelina A; Joseph, Alain; Ayyagari, Rajeev; Mauskopf, Josephine A

2018-01-01

Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobehavioral disorder in children that may persist into adulthood. Lisdexamfetamine dimesylate (LDX) is approved in many countries for ADHD treatment in children, adolescents, and adults. Estimate the cost-effectiveness of LDX as a first- or second-line treatment for adults with ADHD from the United Kingdom (UK) National Health Service (NHS) perspective compared with methylphenidate extended release (MPH-ER) and atomoxetine (ATX). A 1-year decision-analytic model was developed. Health outcomes included response, non-response and inability to tolerate. Efficacy data were obtained from a mixed-treatment comparison (MTC). Response was a score of 1 or 2 on the Clinical Global Impression-Improvement scale. Tolerability was assessed by discontinuation rates due to adverse events. Utilities were identified via a systematic literature review. Health care resource use estimates were obtained via a survey of clinicians. Daily drug costs were estimated from mean doses reported in the trials used in the MTC. One-way and probabilistic sensitivity analyses (PSAs) were performed. LDX dominated MPH-ER and ATX; reducing mean per-patient annual cost by £5 and £200, and increasing mean quality-adjusted life years (QALYs) by 0.005 and 0.009, respectively. In the PSA, the probability of cost-effectiveness for LDX vs. MPH-ER and ATX at a threshold of £20,000 per QALY was 61% and 80%, respectively. From the perspective of the UK NHS, LDX is likely to provide a cost-effective treatment for adults with ADHD. This conclusion may be drawn with more certainty in comparison with ATX than with MPH-ER.

Investigating the role of ion-pair strategy in regulating nicotine release from patch: Mechanistic insights based on intermolecular interaction and mobility of pressure sensitive adhesive.

PubMed

Li, Qiaoyun; Wan, Xiaocao; Liu, Chao; Fang, Liang

2018-07-01

The aim of this study was to prepare a drug-in-adhesive patch of nicotine (NIC) and use ion-pair strategy to regulate drug delivery rate. Moreover, the mechanism of how ion-pair strategy regulated drug release was elucidated at molecular level. Formulation factors including pressure sensitive adhesives (PSAs), drug loading and counter ions (C 4 , C 6 , C 8 , C 10 , and C 12 ) were screened. In vitro release experiment and in vitro transdermal experiment were conducted to determine the rate-limiting step in drug delivery process. FT-IR and molecular modeling were used to characterize the interaction between drug and PSA. Thermal analysis and rheology study were conducted to investigate the mobility variation of PSA. The optimized patch prepared with NIC-C 8 had the transdermal profile fairly close to that of the commercial product (p > 0.05). The release rate constants (k) of NIC, NIC-C 4 and NIC-C 10 were 21.1, 14.4 and 32.4, respectively. Different release rates of NIC ion-pair complexes were attributed to the dual effect of ion-pair strategy on drug release. On one hand, ion-pair strategy enhanced the interaction between drug and PSA, which inhibited drug release. On the other hand, using ion-pair strategy improved the mobility of PSA, which facilitated drug release. Drug release behavior was determined by combined effect of two aspects above. These conclusions provided a new idea for us to regulate drug release behavior from patch. Copyright © 2018 Elsevier B.V. All rights reserved.

Prevalence of microdeletion 22q11 in patients with hypernasal speech due to velopharyngeal insufficiency: Expanded phenotype and clinical comparison to nondeletion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Siegel-Bartelt, J.; Cytrynbaum, C.; Witzel, M.A.

1994-09-01

Microdeletion 22q11.2 has been reported as a frequent ethiology of both velocardiofacial (VCF) and DiGeorge syndromes. We have studied the prevalence of microdeletion 22q11 in a group of patients ascertained through a Speech and Language clinic presenting with (1) velopharyngeal insufficiency (VPI) and (2) difficultly in school. Growth parameters were measured, and facies were scored for features of VCF. Microdeletions were detected at locus D22S75 by FISH with probe N25 (Oncor), and at 22q11.2 with high resolution banding analysis (HRB). One child with typical VCF facies was considered to have a deletion at 22q11 with HRB, but is not deletedmore » with N25, indicating that N25 may not detect all deletion patients. An additional 8/30 children tested to date were deleted with the N25 probe. Heart defects were present in only 2/8 deletion patients: VSD/ASD and PS/AS. One N25 deletion patient was atypica; he has a tall, lanky habitus (height = 90%), and facies not characteristic of CVF. As expected, there is a trend to lower head size, smaller ear size, and more typical facies in deletion patients; however, four of the nondeletion patients also had a clinical diagnosis of VCF. Medially displaced carotid arteries were present in both groups, which is therefore not a diagnostic feature of microdeletion 22q11. Our findings indicate that the microdeletion 22q11 is frequent (26% in this series) in a population with VPI, even when not selected for typical facies. We believe this series supports the view that microdeletion 22q11 has a broader clinical phenotype than previously recognized.« less

Stabilization of Pt monolayer catalysts under harsh conditions of fuel cells

DOE PAGES

Zhang, Xiaoming; Liu, Ping; Yu, Shansheng; ...

2015-05-21

We employed density functional theory (DFT) to explore the stability of core (M = Cu, Ru, Rh, Pd, Ag, Os, Ir, Au)-shell (Pt) catalysts under harsh conditions, including solutions and reaction intermediates involved in the oxygen reduction reaction (ORR) in fuel cells. A pseudomorphic surface alloy (PSA) with a Pt monolayer (Pt 1ML) supported on an M surface, Pt 1ML/M(111) or (001), was considered as a model system. Different sets of candidate M cores were identified to achieve a stable Pt 1ML shell depending on the conditions. In vacuum conditions, the Pt 1ML shell can be stabilized on the mostmore » of M cores except Cu, Ag, and Au. The situation varies under various electrochemical conditions. Depending on the solutions and the operating reaction pathways of the ORR, different M should be considered. Pd and Ir are the only core metals studied, being able to keep the Pt ML shell intact in perchloric acid, sulfuric acid, phosphoric acid, and alkaline solutions as well as under the ORR conditions via different pathways. Ru and Os cores should also be paid attention, which only fall during the ORR via the *OOH intermediate. Rh core works well as long as the ORR does not undergo the pathway via *O intermediate. Our results show that PSAs can behave differently from the near surface alloy, Pt 1ML/M 1ML/Pt(111), highlighting the importance of considering both chemical environments and the atomic structures in rational design of highly stable core-shell nanocatalysts. Finally, the roles that d-band center of a core M played in determining the stability of supported Pt 1ML shell were also discussed.« less

Stabilization of Pt monolayer catalysts under harsh conditions of fuel cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Xiaoming; Yu, Shansheng; Zheng, Weitao, E-mail: wtzheng@jlu.edu.cn, E-mail: pingliu3@bnl.gov

2015-05-21

We employed density functional theory to explore the stability of core (M = Cu, Ru, Rh, Pd, Ag, Os, Ir, Au)-shell (Pt) catalysts under harsh conditions, including solutions and reaction intermediates involved in the oxygen reduction reaction (ORR) in fuel cells. A pseudomorphic surface alloy (PSA) with a Pt monolayer (Pt{sub 1ML}) supported on an M surface, Pt{sub 1ML}/M(111) or (001), was considered as a model system. Different sets of candidate M cores were identified to achieve a stable Pt{sub 1ML} shell depending on the conditions. In vacuum conditions, the Pt{sub 1ML} shell can be stabilized on the most ofmore » M cores except Cu, Ag, and Au. The situation varies under various electrochemical conditions. Depending on the solutions and the operating reaction pathways of the ORR, different M should be considered. Pd and Ir are the only core metals studied, being able to keep the Pt{sub ML} shell intact in perchloric acid, sulfuric acid, phosphoric acid, and alkaline solutions as well as under the ORR conditions via different pathways. Ru and Os cores should also be paid attention, which only fall during the ORR via the *OOH intermediate. Rh core works well as long as the ORR does not undergo the pathway via *O intermediate. Our results show that PSAs can behave differently from the near surface alloy, Pt{sub 1ML}/M{sub 1ML}/Pt(111), highlighting the importance of considering both chemical environments and the atomic structures in rational design of highly stable core-shell nanocatalysts. Finally, the roles that d-band center of a core M played in determining the stability of supported Pt{sub 1ML} shell were also discussed.« less

Emotional Appeals in HIV Prevention Campaigns: Unintended Stigma Effects.

PubMed

Thainiyom, Prawit; Elder, Katherine

2017-07-01

The purpose of this study was to determine whether HIV/AIDS public service announcements (PSAs) that use emotional appeals have unintended effects of creating stigmatizing attitudes in their viewers. We analyzed data for 240 respondents located in the United States who were recruited online. Respondents were randomly assigned to one of 3 conditions, where they viewed a PSA with hope appeals, fear appeals, or non-emotional appeals. Respondents then answered a series of questions about their attitudes about HIV/AIDS; testing behavior; engagement with HIV/AIDS-related people, organizations, and issues; and HIV/AIDS knowledge. We then performed MANOVA analyses and Pearson correlations. There were no significant differences in stigmatizing attitudes and behavior across the 3 conditions. However, once the data were split by sex, men exposed to the hope condition had significantly higher stigmatizing attitudes towards people living with HIV/AIDS than men in the other 2 conditions. This result was unexpected and suggests that further research needs to be conducted with a more robust sample size to account for any moderating influences that might explain why a hopeful message that communicates togetherness would have a negative attitudinal impact on male viewers.

GRiP - A flexible approach for calculating risk as a function of consequence, vulnerability, and threat.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whitfield, R. G.; Buehring, W. A.; Bassett, G. W.

2011-04-08

Get a GRiP (Gravitational Risk Procedure) on risk by using an approach inspired by the physics of gravitational forces between body masses! In April 2010, U.S. Department of Homeland Security Special Events staff (Protective Security Advisors [PSAs]) expressed concern about how to calculate risk given measures of consequence, vulnerability, and threat. The PSAs believed that it is not 'right' to assign zero risk, as a multiplicative formula would imply, to cases in which the threat is reported to be extremely small, and perhaps could even be assigned a value of zero, but for which consequences and vulnerability are potentially high.more » They needed a different way to aggregate the components into an overall measure of risk. To address these concerns, GRiP was proposed and developed. The inspiration for GRiP is Sir Isaac Newton's Universal Law of Gravitation: the attractive force between two bodies is directly proportional to the product of their masses and inversely proportional to the squares of the distance between them. The total force on one body is the sum of the forces from 'other bodies' that influence that body. In the case of risk, the 'other bodies' are the components of risk (R): consequence, vulnerability, and threat (which we denote as C, V, and T, respectively). GRiP treats risk as if it were a body within a cube. Each vertex (corner) of the cube represents one of the eight combinations of minimum and maximum 'values' for consequence, vulnerability, and threat. The risk at each of the vertices is a variable that can be set. Naturally, maximum risk occurs when consequence, vulnerability, and threat are at their maximum values; minimum risk occurs when they are at their minimum values. Analogous to gravitational forces among body masses, the GRiP formula for risk states that the risk at any interior point of the box depends on the squares of the distances from that point to each of the eight vertices. The risk value at an interior (movable) point will be dominated by the value of one vertex as that point moves closer and closer to that one vertex. GRiP is a visualization tool that helps analysts better understand risk and its relationship to consequence, vulnerability, and threat. Estimates of consequence, vulnerability, and threat are external to GRiP; however, the GRiP approach can be linked to models or data that provide estimates of consequence, vulnerability, and threat. For example, the Enhanced Critical Infrastructure Program/Infrastructure Survey Tool produces a vulnerability index (scaled from 0 to 100) that can be used for the vulnerability component of GRiP. We recognize that the values used for risk components can be point estimates and that, in fact, there is uncertainty regarding the exact values of C, V, and T. When we use T = t{sub o} (where t{sub o} is a value of threat in its range), we mean that threat is believed to be in an interval around t{sub o}. Hence, a value of t{sub o} = 0 indicates a 'best estimate' that the threat level is equal to zero, but still allows that it is not impossible for the threat to occur. When t{sub o} = 0 but is potentially small and not exactly zero, there will be little impact on the overall risk value as long as the C and V components are not large. However, when C and/or V have large values, there can be large differences in risk given t{sub o} = 0, and t{sub o} = epsilon (where epsilon is small but greater than a value of zero). We believe this scenario explains the PSA's intuition that risk is not equal to zero when t{sub o} = 0 and C and/or V have large values. (They may also be thinking that if C has an extremely large value, it is unlikely that T is equal to 0; in the terrorist context, T would likely be dependent on C when C is extremely large.) The PSAs are implicitly recognizing the potential that t{sub o} = epsilon. One way to take this possible scenario into account is to replace point estimates for risk with interval values that reflect the uncertainty in the risk components. In fact, one could argue that T never equals zero for a man-made hazard. This paper describes the thought process that led to the GRiP approach and the mathematical formula for GRiP and presents a few examples that will provide insights about how to use GRiP and interpret its results.« less

Comparing the Epica and Vostok dust records during the last 220,000 years: stratigraphical correlation and provenance in glacial periods

NASA Astrophysics Data System (ADS)

Delmonte, B.; Basile-Doelsch, I.; Petit, J.-R.; Maggi, V.; Revel-Rolland, M.; Michard, A.; Jagoutz, E.; Grousset, F.

2004-06-01

A new aeolian dust record from the first 2200 m of the EPICA-Dome C ice core (75°06'S, 123°21'E) covering about 220,000 years of climatic history is compared to the Vostok (78°28'S, 106°48'E) ice core [Nature 399 (1999) 429]. The two dust profiles are very similar and several common dust events allow to establish stratigraphical links. The late Quaternary period is characterized at both sites, and likely overall East Antarctic plateau, by high dust input during glacial periods. In the EPICA-Dome C ice core, the dust flux rises by a factor of ˜25, ˜20 and ˜12 in glacial stages 2, 4 and 6 with respect to interglacial periods (Holocene and stage 5.5). The magnitude and pattern of changes are comparable in the Vostok ice core. In this study, the geographical origin of ice core dust (ICD) in cold periods has been investigated at both sites through 87Sr/ 86Sr versus 143Nd/ 144Nd isotopic tracers, following the previous studies of Grousset et al. [Earth Planet. Sci. Lett. 111 (1992) 175] and Basile et al. [Earth Planet. Sci. Lett. 146 (1997) 573]. The new data and the existing ones allow to define the isotopic fields for dust at the two Antarctic sites that are almost identical and restricted into the 0.708< 87Sr/ 86Sr<0.711 and -5< ɛNd(0)<+5 ranges. This suggests a common geographical provenance for dust at Vostok and Dome C and for all the glacial periods of the late Pleistocene. To decipher the ICD provenance, more than 50 samples of loess and aeolian deposits, sands and fluvioglacial sediments from the Potential Source Areas (PSAs) of the Southern Hemisphere have been collected. However, the methodology has been refined with respect to former studies. First, the isotopic fractionation that can occur in function of grain size has been taken into account, and the PSA's signature has been defined in the <5 μm size range, within which fine-grained dust reaching Antarctica is found. Moreover, a possible contribution from carbonates on the samples from PSAs has also been also considered. South Africa and Australia can be excluded as dominant sources, but a partial overlap arises among southern South America, New Zealand and the Antarctic Dry Valleys isotopic fields, these latter two documented for the first time. A possible contribution from all these three sources cannot be excluded, but complementary arguments suggest the dominant contribution to East Antarctic dust in glacial times deriving from the southern South American region of Patagonia and the Pampas. This study shows a first-order uniformity in the dust flux and geographical provenance to the East Antarctica plateau during glacial periods.

Obesity in African-American Women--The Time Bomb is Ticking: An Urgent Call for Change.

PubMed

Fowler, Barbara A

2015-12-01

The "time bomb is ticking" because there is an obesity crisis associated with higher rates of chronic diseases such as stroke, hypertension, type 2 diabetes, and some forms of cancer in African-American women compared to White women. African-American women incur higher medical costs from hospitalizations, decreased productivity in the work setting, lost wages, the needfor medical benefits and pharmacy-associated costs, and more time away from family than White women. Numerous factors, such as the socio-cultural context of eating, acceptance of a larger weight status, the emotionally liberating effects offood, and preference for highfat and high caloric, sugary-content, and sodium-laden food influences the obesity crisis in African-American women. The interplay of poverty and lower socioeconomic status, residential segregation, health literacy, availability of fast foods and scarce produce in local convenience food marts, physical inactivity, and conflicting messages from social media public service announcements (PSAs) and ads in national magazines affect the obesity crisis in African-American women. There is an urgent call for sustainable, community-driven health policy initiatives that improve access to healthy foods in lower-income, minority communities. Furthermore, African-American women are challenged to modify their health behaviors by preparing healthy meals for themselves and theirfamilies, and by engaging in physical activity.

Probabilistic seismic hazard at the archaeological site of Gol Gumbaz in Vijayapura, south India

NASA Astrophysics Data System (ADS)

Patil, Shivakumar G.; Menon, Arun; Dodagoudar, G. R.

2018-03-01

Probabilistic seismic hazard analysis (PSHA) is carried out for the archaeological site of Vijayapura in south India in order to obtain hazard consistent seismic input ground-motions for seismic risk assessment and design of seismic protection measures for monuments, where warranted. For this purpose the standard Cornell-McGuire approach, based on seismogenic zones with uniformly distributed seismicity is employed. The main features of this study are the usage of an updated and unified seismic catalogue based on moment magnitude, new seismogenic source models and recent ground motion prediction equations (GMPEs) in logic tree framework. Seismic hazard at the site is evaluated for level and rock site condition with 10% and 2% probabilities of exceedance in 50 years, and the corresponding peak ground accelerations (PGAs) are 0.074 and 0.142 g, respectively. In addition, the uniform hazard spectra (UHS) of the site are compared to the Indian code-defined spectrum. Comparisons are also made with results from National Disaster Management Authority (NDMA 2010), in terms of PGA and pseudo spectral accelerations (PSAs) at T = 0.2, 0.5, 1.0 and 1.25 s for 475- and 2475-yr return periods. Results of the present study are in good agreement with the PGA calculated from isoseismal map of the Killari earthquake, {M}w = 6.4 (1993). Disaggregation of PSHA results for the PGA and spectral acceleration ({S}a) at 0.5 s, displays the controlling scenario earthquake for the study region as low to moderate magnitude with the source being at a short distance from the study site. Deterministic seismic hazard (DSHA) is also carried out by taking into account three scenario earthquakes. The UHS corresponding to 475-yr return period (RP) is used to define the target spectrum and accordingly, the spectrum-compatible natural accelerograms are selected from the suite of recorded accelerograms.

Are labour-intensive efforts to prevent pressure ulcers cost-effective?

PubMed

Mathiesen, Anne Sofie Mølbak; Nørgaard, Kamilla; Andersen, Marie Frederikke Bruun; Møller, Klaus Meyer; Ehlers, Lars Holger

2013-10-01

Pressure ulcers are a major problem in Danish healthcare with a prevalence of 13-43% among hospitalized patients. The associated costs to the Danish Health Care Sector are estimated to be €174.5 million annually. In 2010, The Danish Society for Patient Safety introduced the Pressure Ulcer Bundle (PUB) in order to reduce hospital-acquired pressure ulcers by a minimum of 50% in five hospitals. The PUB consists of evidence-based preventive initiatives implemented by ward staff using the Model for Improvement. To investigate the cost-effectiveness of labour-intensive efforts to reduce pressure ulcers in the Danish Health Care Sector, comparing the PUB with standard care. A decision analytic model was constructed to assess the costs and consequences of hospital-acquired pressure ulcers during an average hospital admission in Denmark. The model inputs were based on a systematic review of clinical efficacy data combined with local cost and effectiveness data from the Thy-Mors Hospital, Denmark. A probabilistic sensitivity analysis (PSA) was conducted to assess the uncertainty. Prevention of hospital-acquired pressure ulcers by implementing labour-intensive effects according to the PUB was cost-saving and resulted in an improved effect compared to standard care. The incremental cost of the PUB was -€38.62. The incremental effects were a reduction of 9.3% prevented pressure ulcers and 0.47% prevented deaths. The PSAs confirmed the incremental cost-effectiveness ratio (ICER)'s dominance for both prevented pressure ulcers and saved lives with the PUB. This study shows that labour-intensive efforts to reduce pressure ulcers on hospital wards can be cost-effective and lead to savings in total costs of hospital and social care. The data included in the study regarding costs and effects of the PUB in Denmark were based on preliminary findings from a pilot study at Thy-Mors Hospital and literature.

Suicide Prevention Public Service Announcements Impact Help-Seeking Attitudes: The Message Makes a Difference

PubMed Central

Klimes-Dougan, Bonnie; Wright, Nathan; Klingbeil, David A.

2016-01-01

Suicide continues to be one of the most serious public health challenges. Public service announcements (PSAs) are frequently used to address this challenge, but are rarely sufficiently evaluated to determine if they meet the intended goals, or are associated with potential iatrogenic effects. Although it is challenging to assess the relative impact of different PSA modalities, our group previously noted that one billboard message failed to show the same benefits as one TV ad [e.g., Klimes-Dougan and Lee (1)]. The purpose of this study was to extend these findings to test critical aspects of suicide prevention billboard messaging. Although both simulated billboard messages presented had identical supporting messages, we predicted that the more personal billboard message, focused on saving one’s life, would cause more favorable help-seeking attitudes than the message focused on suicide. Young adult university students (N = 785) were randomly assigned to one of three conditions; one of two billboard simulations or a TV ad simulation. Help-seeking attitudes, maladaptive coping, and reports of concern and distress were evaluated. The results of this study suggest some relative benefits in endorsement of favorable help-seeking attitudes for one of the billboard conditions – stop depression from taking another life. Although further research is needed to determine what methods will alter the risk for suicide in the population, the results of this study provide a useful first step showing that some billboard messaging may favorably influence help-seeking attitudes. PMID:27471477

Suicide Prevention Public Service Announcements Impact Help-Seeking Attitudes: The Message Makes a Difference.

PubMed

Klimes-Dougan, Bonnie; Wright, Nathan; Klingbeil, David A

2016-01-01

Suicide continues to be one of the most serious public health challenges. Public service announcements (PSAs) are frequently used to address this challenge, but are rarely sufficiently evaluated to determine if they meet the intended goals, or are associated with potential iatrogenic effects. Although it is challenging to assess the relative impact of different PSA modalities, our group previously noted that one billboard message failed to show the same benefits as one TV ad [e.g., Klimes-Dougan and Lee (1)]. The purpose of this study was to extend these findings to test critical aspects of suicide prevention billboard messaging. Although both simulated billboard messages presented had identical supporting messages, we predicted that the more personal billboard message, focused on saving one's life, would cause more favorable help-seeking attitudes than the message focused on suicide. Young adult university students (N = 785) were randomly assigned to one of three conditions; one of two billboard simulations or a TV ad simulation. Help-seeking attitudes, maladaptive coping, and reports of concern and distress were evaluated. The results of this study suggest some relative benefits in endorsement of favorable help-seeking attitudes for one of the billboard conditions - stop depression from taking another life. Although further research is needed to determine what methods will alter the risk for suicide in the population, the results of this study provide a useful first step showing that some billboard messaging may favorably influence help-seeking attitudes.

Strategies of media marketing for "America Responds to AIDS" and applying lessons learned.

PubMed Central

Keiser, N H

1991-01-01

The Centers for Disease Control's (CDC) public service announcement (PSA) campaign on acquired immunodeficiency syndrome (AIDS), entitled "America Responds to AIDS," has provided an opportunity to examine various media marketing techniques and their effectiveness in setting and sustaining a national media agenda for public health. The overall objective was to enlist the media as a partner in the effort to establish a clear national public health agenda on AIDS by reaching as many Americans as possible with disease prevention information in a credible and acceptable way. In order for the media to become interested in a subject traditionally treated as health information rather than a "news story," CDC identified and employed various methods and tools to generate coverage. These included the use of news conferences, video and audio news releases, satellite interviews, and press kits developed for each phase of the campaign. News "hooks" were used to grab attention; for example, the use of well-known public health spokespersons in media events or the promotion of free collateral materials. The marketing approach undertaken for each phase of the campaign varied, and lessons were learned and applied along the way. A model emerged indicating that a combination of techniques could result in maximum exposure in both news stories and public affairs programming. Because the model allowed messages to be delivered credibly and consistently, the result was increased usage of the PSAs to coincide with the media coverage. PMID:1659707

Chemical composition of size-segregated aerosol collected all year-round at Concordia Station (Dome C, Antarctica). Transport processes and climatic implications.

NASA Astrophysics Data System (ADS)

Udisti, Roberto; Becagli, Silvia; Frosini, Daniele; Galli, Gaia; Ghedini, Costanza; Rugi, Francesco; Severi, Mirko; Traversi, Rita

2010-05-01

Ice-core stratigraphies of chemical components of atmospheric gases and aerosols trapped in the snow layers by scavenging processes are a powerful tool in understanding past climatic and environmental changes. The deep ice core drilled at Dome C in the framework of the EPICA project allowed reconstructing the last 8 glacial-interglacial cycles and highlightened the complex relationships between climatic forcings and environmental feedback processes. In interpreting ice core records as a function of past climatic variations, some difficulties arise from uncertainties in considering selected chemical species as reliable markers of climatic and environmental processes and in attributing the different load and composition of aerosols over Antarctica to changes in source intensity (such as aridity, wind strength, emersion of continental platform by sea-level lowering etc..) and/or to variations in atmospheric processes (such as meridional and zonal atmospheric circulation, polar vortex intensity, scavenging efficiency, transport pathways etc..). Besides, two new aspects are actually under discussions: the possible use of Na as sea-ice cover marker (via frost flower formation on the sea-ice surface during the pack-ice formation) and the identification of continental source areas for mineral dust reaching internal regions of Antarctica during glacial and interglacial periods. In order to better address such controversial issues, since 2005 a continuous, high temporal resolution size-segregated aerosol and surface snow sampling has been performed at Dome C (central East Antarctic Plateau, 75° 06' S, 123° 23' E), in the framework of "Station Concordia" Project (a Italian PNRA- French IPEV joint program). The chemical analysis of size-segregated aerosol and daily superficial snow samples, collected all year-round for more than 4 years, can contribute to clarify some of the above mentioned topics. In particular: the possible seasonal pattern of sea spray aerosol could be related to sea-ice formation timing and/or to changes in zonal wind intensity and atmospheric pathway; the mineralogical analysis of insoluble dust particles can allow the identification of continental sources, by comparison with soils collected in the potential source areas (PSAs); finally, the seasonal pattern of biogenic markers (such as methanesulphonic acid and non-sea-salt sulphate) can be linked to sea surface temperature, sea-ice cover and southern-hemisphere circulation modes (e.g., SOI, AAO or SAM and ACW). As regard as depositional and post-depositional processes, the analysis of chemical markers in aerosol, superficial snow and hoar crystals, sampled contemporaneously, will allow understanding the key factors (e.g., snow acidity, solar irradiation) affecting the preservation of components reversibly fixed in the snow layers (such as, for instance, methanesulphonic acid, nitrate and chloride). A summary of the major results from the chemical analysis of aerosol and snow collected at Dome C is here presented.

Wilderness experience in Rocky Mountain National Park 2002; report to respondents

USGS Publications Warehouse

Schuster, Elke; Johnson, S. Shea; Taylor, Jonathan G.

2003-01-01

A substantial amount of backcountry (about 250,000 acres) in Rocky Mountain National Park [RMNP of the Park] may be designated as wilderness areas in the coming years. Currently, over 3 million visitors drives through the park on Trail Ridge Road, camp in designated campgrounds, day hike, etc. each year. Many of those visitors also report using the backcountry-wilderness areas that are not easily accessible by roads or trails. Use of the backcountry is growing at RMNP and is accompanied by changing visitor expectations and preferences for wilderness management. For these reasons it is of great importance for the Park to periodically assess what types of environments and conditions wilderness users seek to facilitate a quality experience. To assist in this effort, the Political Analysis and Science Assistance [PSAS] program / Fort Collins Center / U.S. Geological Survey, in close collaboration with personnel and volunteers from RMNP, as well as the Natural Resource Recreation and Tourism [NRRT] Department at Colorado State University, launched a research effort in the summer of 2002 to investigate visitorsa?? wilderness experiences in the Park. Specifically, the purpose of this research was: (1) To determine what constitutes a wilderness experience; (2) To identify important places, visual features, and sounds essential to a quality wilderness experience and; (3) To determine what aspects may detract from wilderness experience. Thus, answers to these questions should provide insight for Park managers about visitorsa?? expectation for wilderness recreation and the conditions they seek for quality wilderness experiences. Ultimately, this information can be used to support wilderness management decisions within RMNP. The social science technique of Visitor Employed Photography [VEP] was used to obtain information from visitors about wilderness experiences. Visitors were selected at random from Park-designated wilderness trails, in proportion to their use, and asked to participate in the survey. Respondents were given single use, 10-exposure cameras and photo-log diaries to record experiences. A total of 293 cameras were distributed, with a response rate of 87%. Following the development of the photos, a copy of the photos, two pertinent pages from the photo-log, and a follow-up survey were mailed to respondents. Fifty-six percent of the follow-up surveys were returned. Findings from the two surveys were analyzed and compareda?|

SES discrepancies and Delaware cancer death rates.

PubMed

Frelick, Robert W

2004-03-01

Cancer can be monitored fairly effectively by using cancer registry data for site, stage, age, sex, and race. Adding to this the patient's years of education, now only found on death certificates, should not be difficult since it is an easily measured major SES factor. Most comorbidities should also be easy to obtain since hospitals usually code them. Capturing all treatment and response data remains a challenge as more and more cancer diagnosis and management is done in outpatient settings. Current efforts to establish electronic medical records in compliance with the Health Insurance Portability and Accountability Act (HIPAA) may be a blessing if adequate software can be standardized and used similar to that already present in the VA hospital in Delaware. Such information would aid efforts to reduce Delaware's high cancer incidence and mortality rates. A proposed state cancer plan should stimulate improved integration of the state's health resources to focus on the quality of individual health care and to use cost-effective measures to improve the public's health. A plan should (1) stimulate a public awareness to reduce risk factors for all major chronic diseases with a special focus on cancer deaths; (2) use medical office settings to provide simple screens to improve the early detection of a number of chronic diseases depending on such risks as age and sex (such studies might include weight, height, blood pressure, sugar, cholesterol, PSAs, exams of skin, oral cavities, breasts, abdomen, rectum, and vagina with pap smears, all of which can be accomplished in a cost-effective fashion); and (3) offer equitable access to a state's health care system for information, screening, and treatment. Current evidence shows that it is less expensive to manage patients with early cancers than those with advanced cases, which often occur because of ignorance and lack of access to health services, and by socioeconomic, educational, and cultural barriers. Implementing the recommendations in the Governor's Advisory Council's report should go a long way toward reducing both Delaware's cancer incidence and death rates. An increase in taxes on tobacco (one of the Council's recommendations) could provide resources to explore relationships between the environment, occupation, and cancer, and provide early access to competent cancer care for those at risk because of limited education, income, and health insurance.

Percutaneous Treatment of Iatrogenic Pseudoaneurysms by Cyanoacrylate-Based Wall-Gluing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Del Corso, Andrea, E-mail: adelcorso2000@hotmail.com; Vergaro, Giuseppe

Purpose. Although the majority of iatrogenic pseudoaneurysms (PSAs) are amenable to ultrasound (US)-guided thrombin injection, patients with those causing neuropathy, claudication, significant venous compression, or soft tissue necrosis are considered poor candidates for this option and referred to surgery. We aimed to test the effectiveness and feasibility of a novel percutaneous cyanoacrylate glue (NBCA-MS)-based technique for treatment of symptomatic and asymptomatic iatrogenic PSA. Material and Methods. During a 3-year period, we prospectively enrolled 91 patients with iatrogenic PSA [total n = 94 (femoral n = 76; brachial n = 11; radial n = 6; axillary n = 1)]. PSA weremore » asymptomatic in 66 % of cases, and 34 % presented with symptoms due to neuropathy, venous compression, and/or soft tissue necrosis. All patients signed informed consent. All patients received NBCA-MS-based percutaneous treatment. PSA chamber emptying was first obtained by US-guided compression; superior and inferior walls of the PSA chamber were then stuck together using NBCA-MS microinjections. Successfulness of the procedure was assessed immediately and at 1-day and 1-, 3-, and 12-month US follow-up. Results. PSA occlusion rate was 99 % (93 of 94 cases). After treatment, mean PSA antero-posterior diameter decrease was 67 {+-} 22 %. Neuropathy and vein compression immediately disappeared in 91 % (29 of 32) of cases. Patients with tissue necrosis (n = 6) underwent subsequent outpatient necrosectomy. No distal embolization occurred, nor was conversion to surgery necessary. Conclusion. PSA treatment by way of NBCA-MS glue injection proved to be safe and effective in asymptomatic patients as well as those with neuropathy, venous compression, or soft-tissue necrosis (currently candidates for surgery). Larger series are needed to confirm these findings.« less

Evaluation of an Aggressive Prostate Biopsy Strategy in Men Younger than 50 years of Age.

PubMed

Goldberg, Hanan; Klaassen, Zachary; Chandrasekar, Thenappan; Wallis, Christopher J D; Toi, Ants; Sayyid, Rashid; Bhindi, Bimal; Nesbitt, Michael; Evans, Andrew; van der Kwast, Theo; Sweet, Joan; Perlis, Nathan; Hamilton, Robert J; Kulkarni, Girish S; Finelli, Antonio; Zlotta, Alexandre; Fleshner, Neil

2018-05-11

Longitudinal cohort studies and guidelines demonstrate that PSA ≥1 ng/mL in younger patients confer an increased risk of delayed prostate cancer (PC) death. In our institution we have used an aggressive biopsy strategy among younger patients with PSA of>1 ng/ml. Our objective was to determine the proportion of detected cancer and specifically, clinical significant cancer, with this strategy. The prostate biopsy (PB) database at Princess Margaret Cancer Centre was queried for patients younger than 50 who underwent a first PB between 2000 and 2016. We included only patients undergoing PB due to PSA>1 ng/mL, suspicious digital rectal examination, positive family history (PFH), or suspicious lesion on trans-rectal ultrasound. All clinical and pathological parameters were analyzed. Patients were stratified according to their specific PSA values. Multivariable logistic regression was performed to ascertain predictors of any PC diagnosis, and of clinically significant PC. Of 199 patients who met the inclusion criteria, 37 (19%) were diagnosed with PC and 8 (22%) had a Gleason score (GS)>7. Of those diagnosed with PC, 25 (68%) had a PSA>1.5 ng/ml and all men with GS>7 had PSA>1.5 ng/ml. Notably, 19 (51%) patients had PC exceeding Epstein criteria for active surveillance. Factors predicting PC included PFH, rising PSA and lower prostate volumes. Our results justify adopting an aggressive PB strategy for young men<50 years old with a PSA>1.5 ng/ml, while patients with PSAs<1.5 ng/ml are unlikely to have significant cancer. Special attention should be paid to patients with smaller prostates, and PFH. Copyright © 2018 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

It only takes once: The absent-exempt heuristic and reactions to comparison-based sexual risk information

PubMed Central

Stock, Michelle L.; Gibbons, Frederick X.; Beekman, Janine B.; Gerrard, Meg

2015-01-01

Three studies (N = 545) investigated the effects of social comparison on a type of heuristic called “absent-exempt” (AE; feeling exempt from future risk). Study 1 examined how comparison with an infected peer (comparison target) who was similar or non-similar in terms of sexual risk (number of partners, lack of condom use), influenced willingness and intentions to engage in sex without a condom and conditional perceived vulnerability to a sexually transmitted disease (STD). Participants generally reported lower willingness and higher conditional vulnerability if they compared with a similar-risk level target. However, high-risk students who compared with a low-risk comparison target engaged in what appeared to be AE thinking, reporting the highest willingness and lowest conditional vulnerability. Intentions to have sex without a condom were not influenced. Study 2 included a direct measure of AE thinking, and compared the impact of a low-risk comparison target with a Public Service Announcement (PSA) stating that negative outcomes (e.g., STDs) can happen even to low-risk targets. Among high-risk participants, comparing with the low-risk target led to an increase in AE thinking. As expected, the effects in Studies 1 and 2 were strongest among participants high in tendencies to socially compare. Study 3 explored whether AE thinking could be decreased by encouraging more reasoned processing. Results indicated that asking participants to think about the illogicality of AE thinking reduces AE endorsement and increases STD testing intentions. Findings suggest that comparison-based information can have a stronger influence on health cognitions than analytic-based information (e.g., most PSAs). Implications for dual-processing models of decision-making and their applicability to interventions and health messages are discussed. PMID:26098587

Influences of conformations of peptides on stereoinversions and/or isomerizations of aspartic acid residues.

PubMed

Oda, Akifumi; Nakayoshi, Tomoki; Fukuyoshi, Shuichi; Kurimoto, Eiji; Takahashi, Ohgi

2018-07-01

Recently, non-enzymatic stereoinversions of aspartic acid (Asp) residues in proteins and peptides have been reported. Here, we performed replica exchange molecular dynamics (REMD) simulations of model peptides (exon 6, 26A-1, and 26A-2) extracted from elastin to investigate their structural features, thereby revealing the factor that influences stereoinversions. For REMD trajectories, we calculated distances between carboxyl carbon in Asp and amide nitrogen in the (n + 1) residue (CN distances). Because bond formation between carbon and nitrogen is indispensable to the formation of a succinimide intermediate the distance between them seems to play an important role in stereoinversion. Moreover, we calculated polar surface areas (PSAs) for the trajectories, finding that CN distances and PSA were different for each peptide, with the longest CN distance and smallest PSA observed for exon 6 peptide, where stereoinversion of Asp is the slowest. Although the average CN distance was shorter for exon 26A-1 peptide than for exon 26A-2 peptide, the number of conformations with CN distances <3.0 Å was greater for exon 26A-2 peptide than for exon 26A-1 peptide. Furthermore, PSA for amide nitrogen of the (n + 1) residue was larger for exon 26A-2 peptide than for exon 26A-1 peptide. These results indicated that the flexibility of Asp and (n + 1) residues and hydrophilicity of peptides, especially in the (n + 1) residue, play important roles in the stereoinversion of Asp. This article is part of a Special Issue entitled: D-Amino acids: biology in the mirror, edited by Dr. Loredano Pollegioni, Dr. Jean-Pierre Mothet and Dr. Molla Gianluca. Copyright © 2018 Elsevier B.V. All rights reserved.

It only takes once: The absent-exempt heuristic and reactions to comparison-based sexual risk information.

PubMed

Stock, Michelle L; Gibbons, Frederick X; Beekman, Janine B; Gerrard, Meg

2015-07-01

Three studies (N = 545) investigated the effects of social comparison on the "absent-exempt" (AE) heuristic (feeling exempt from future risk). Study 1 examined how comparison with an infected peer (comparison target) who was similar or nonsimilar in terms of sexual risk (number of partners, lack of condom use), influenced willingness and intentions to engage in sex without a condom, and conditional perceived vulnerability to an STD. Participants generally reported lower willingness and higher conditional vulnerability if they compared with a similar-risk level target. However, high-risk students who compared with a low-risk target engaged in what appeared to be AE thinking, reporting the highest willingness and lowest conditional vulnerability. Intentions to have sex without a condom were not influenced. Study 2 included a direct measure of AE thinking and compared the impact of a low-risk comparison target with a Public Service Announcement (PSA) stating that negative outcomes (STDs) can happen even to low-risk targets. Among high-risk participants, comparing with the low-risk target increased AE thinking. The effects in Studies 1 and 2 were strongest among participants high in tendencies to socially compare. Study 3 explored whether AE thinking could be decreased by encouraging more reasoned processing. Results indicated that asking participants to think about the illogicality of AE thinking reduces AE endorsement and increases STD testing intentions. Findings suggest that comparison-based information can have a stronger influence on health cognitions than analytic-based information (e.g., most PSAs). Implications for dual-processing models of decision-making and their applicability to health messages are discussed. (c) 2015 APA, all rights reserved).

An Isotopic Map of Dust Source Areas in the McMurdo Sound Sector of Antarctica

NASA Astrophysics Data System (ADS)

Blakowski, M. A.; Aciego, S.; Delmonte, B.; Baroni, C.; Salvatore, M. C.

2014-12-01

The McMurdo Sound sector of Antarctica features a unique, polar desert ecosystem characterized by low temperatures, hyper-aridity, and high-speed winds. These climatic conditions result in limited water sources, sparse vegetation, underdeveloped soils, and abundant unconsolidated sediment easily influenced by wind-driven transport. Radiogenic isotopes (87Sr/86Sr, 143Nd/144Nd) provide constant signatures of dust from source- to sink-areas. Accordingly, aeolian dust derived from arid regions has been recognized in many studies as an important tracer of atmospheric circulation, as well as a tool for deciphering past climatic conditions in dust source regions. However, while major global dust sources (e.g. from South America, Africa, and Asia) are well studied and easily identifiable via distinct isotopic signatures when encountered in different depositional environments (e.g. Antarctic ice cores), local material from sources in and around the ice-free Dry Valleys and surrounding areas have remained in need of further documentation. We analyzed 40 samples of silt, sand, glacial drift, and weathered regolith material in both fine (<5μm) and coarse fractions collected from Victoria Land and the McMurdo Sound sector, including Cape Royds, Cape Bird, and the McMurdo Ice Shelf. Here we present an ArcGIS-generated, high-precision geochemical map of Antarctic PSAs synthesized from our data and combined with geomorphological and stratigraphic information on the studied sites. We believe that our expanded isotopic catalogue and map can be used to enhance and/or prompt regional studies in a variety of disciplines, such as by providing greater constraints on models of regional dust variability and transport pathways and of the melting history of the Antarctic ice sheet, and by determining the provenance of dust archived in ice cores, lake sediment, soil records, and impurities in Antarctic sea-ice.

Intervention effects from a social marketing campaign to promote HPV vaccination in preteen boys

PubMed Central

Cates, Joan R.; Diehl, Sandra J.; Crandell, Jamie L.; Coyne-Beasley, Tamera

2014-01-01

Objectives Adoption of human papillomavirus (HPV) vaccination in the US has been slow. In 2011, HPV vaccination of boys was recommended by CDC for routine use at ages 11–12. We conducted and evaluated a social marketing intervention with parents and providers to stimulate HPV vaccination among preteen boys. Methods We targeted parents and providers of 9–13 year old boys in a 13 county NC region. The 3-month intervention included distribution of HPV vaccination posters and brochures to all county health departments plus 194 enrolled providers; two radio PSAs; and an online CME training. A Cox proportional hazards model was fit using NC immunization registry data to examine whether vaccination rates in 9–13 year old boys increased during the intervention period in targeted counties compared to control counties (n=15) with similar demographics. To compare with other adolescent vaccines, similar models were fit for HPV vaccination in girls and meningococcal and Tdap vaccination of boys in the same age range. Moderating effects of age, race, and Vaccines for Children (VFC) eligibility on the intervention were considered. Results The Cox model showed an intervention effect (β=0.29, HR=1.34, p=.0024), indicating that during the intervention the probability of vaccination increased by 34% in the intervention counties relative to the control counties. Comparisons with HPV vaccination in girls and Tdap and meningococcal vaccination in boys suggest a unique boost for HPV vaccination in boys during the intervention. Model covariates of age, race and VFC eligibility were all significantly associated with vaccination rates (p<.0001 for all). HPV vaccination rates were highest in the 11–12 year old boys. Overall, three of every four clinic visits for Tdap and meningococcal vaccines for preteen boys were missed opportunities to administer HPV vaccination simultaneously. Conclusions Social marketing techniques can encourage parents and health care providers to vaccinate preteen boys against HPV. PMID:24886960

Intervention effects from a social marketing campaign to promote HPV vaccination in preteen boys.

PubMed

Cates, Joan R; Diehl, Sandra J; Crandell, Jamie L; Coyne-Beasley, Tamera

2014-07-16

Adoption of human papillomavirus (HPV) vaccination in the US has been slow. In 2011, HPV vaccination of boys was recommended by CDC for routine use at ages 11-12. We conducted and evaluated a social marketing intervention with parents and providers to stimulate HPV vaccination among preteen boys. We targeted parents and providers of 9-13 year old boys in a 13 county NC region. The 3-month intervention included distribution of HPV vaccination posters and brochures to all county health departments plus 194 enrolled providers; two radio PSAs; and an online CME training. A Cox proportional hazards model was fit using NC immunization registry data to examine whether vaccination rates in 9-13 year old boys increased during the intervention period in targeted counties compared to control counties (n=15) with similar demographics. To compare with other adolescent vaccines, similar models were fit for HPV vaccination in girls and meningococcal and Tdap vaccination of boys in the same age range. Moderating effects of age, race, and Vaccines for Children (VFC) eligibility on the intervention were considered. The Cox model showed an intervention effect (β=0.29, HR=1.34, p=.0024), indicating that during the intervention the probability of vaccination increased by 34% in the intervention counties relative to the control counties. Comparisons with HPV vaccination in girls and Tdap and meningococcal vaccination in boys suggest a unique boost for HPV vaccination in boys during the intervention. Model covariates of age, race and VFC eligibility were all significantly associated with vaccination rates (p<.0001 for all). HPV vaccination rates were highest in the 11-12 year old boys. Overall, three of every four clinic visits for Tdap and meningococcal vaccines for preteen boys were missed opportunities to administer HPV vaccination simultaneously. Social marketing techniques can encourage parents and health care providers to vaccinate preteen boys against HPV. Copyright © 2014 Elsevier Ltd. All rights reserved.

Comparisons of ground motions from five aftershocks of the 1999 Chi-Chi, Taiwan, earthquake with empirical predictions largely based on data from California

USGS Publications Warehouse

Wang, G.-Q.; Boore, D.M.; Igel, H.; Zhou, X.-Y.

2004-01-01

The observed ground motions from five large aftershocks of the 1999 Chi-Chi, Taiwan, earthquake are compared with predictions from four equations based primarily on data from California. The four equations for active tectonic regions are those developed by Abrahamson and Silva (1997), Boore et al. (1997), Campbell (1997, 2001), and Sadigh et al. (1997). Comparisons are made for horizontal-component peak ground accelerations and 5%-damped pseudoacceleration response spectra at periods between 0.02 sec and 5 sec. The observed motions are in reasonable agreement with the predictions, particularly for distances from 10 to 30 km. This is in marked contrast to the motions from the Chi-Chi mainshock, which are much lower than the predicted motions for periods less than about 1 sec. The results indicate that the low motions in the mainshock are not due to unusual, localized absorption of seismic energy, because waves from the mainshock and the aftershocks generally traverse the same section of the crust and are recorded at the same stations. The aftershock motions at distances of 30-60 km are somewhat lower than the predictions (but not nearly by as small a factor as those for the mainshock), suggesting that the ground motion attenuates more rapidly in this region of Taiwan than it does in the areas we compare with it. We provide equations for the regional attenuation of response spectra, which show increasing decay of motion with distance for decreasing oscillator periods. This observational study also demonstrates that ground motions have large earthquake-location-dependent variability for a specific site. This variability reduces the accuracy with which an earthquake-specific prediction of site response can be predicted. Online Material: PGAs and PSAs from the 1999 Chi-Chi earthquake and five aftershocks.

Reimbursement decisions of the All Wales Medicines Strategy Group: influence of policy and clinical and economic factors.

PubMed

Linley, Warren G; Hughes, Dyfrig A

2012-09-01

There have been several explorations of factors influencing the reimbursement decisions of the National Institute for Health and Clinical Excellence (NICE) but not of other UK-based health technology assessment (HTA) organizations. This study aimed to explore the factors influencing the recommendations of the All Wales Medicines Strategy Group (AWMSG) on the use of new medicines in Wales. Based on public data, logistic regression models were developed to evaluate the influence of cost effectiveness, the quality and quantity of clinical evidence, disease characteristics (including rarity), budget impact, and a range of other factors on the recommendations of AWMSG and its subcommittee, the New Medicines Group (NMG). Multivariate analyses of 47 AWMSG appraisals between 2007-9 correctly predicted 87% of decisions. The results are suggestive of a positive influence on recommendations of the presence of probabilistic sensitivity analyses (PSAs) but, counter-intuitively, a statistically significant negative influence of evidence from high-quality randomized controlled trials (RCTs) [odds ratio 0.059; 95% CI 0.005, 0.699]. This latter observation may be attributed to our strict definition of high quality, which excluded the use of surrogate endpoints. Putative explanatory variables, including cost effectiveness, budget impact, underlying disease characteristics and 'ultra'-orphan drug status were not statistically significant predictors of final AWMSG decisions based on our dataset. Univariate analyses indicate that medicines with negative recommendations had significantly higher incremental cost-effectiveness ratios than those with positive recommendations, consistent with the pursuit of economic efficiency. There is also evidence that AWMSG considers equity issues via an ultra-orphan drugs policy. Consideration of decision uncertainty via PSA appears to positively influence the reimbursement decisions of AWMSG. The significant negative impact of the presence of high-quality RCTs, and the lack of a significant positive impact of other expected factors, may reflect issues in the plausibility of supporting evidence for medicines that received negative recommendations. Furthermore, it serves to emphasize the difficulties in applying the usual hierarchies of evidence to the HTA process, and in particular to the appraisal of high-cost specialist medicines close to market launch.

Prostate health index significantly reduced unnecessary prostate biopsies in patients with PSA 2-10 ng/mL and PSA >10 ng/mL: Results from a Multicenter Study in China.

PubMed

Na, Rong; Ye, Dingwei; Qi, Jun; Liu, Fang; Helfand, Brian T; Brendler, Charles B; Conran, Carly A; Packiam, Vignesh; Gong, Jian; Wu, Yishuo; Zheng, Siqun L; Mo, Zengnan; Ding, Qiang; Sun, Yinghao; Xu, Jianfeng

2017-08-01

The performance of prostate health index (phi) in predicting prostate biopsy outcomes has been well established for patients with prostate-specific antigen (PSA) values between 2 and 10 ng/mL. However, the performance of phi remains unknown in patients with PSA >10 ng/mL, the vast majority in Chinese biopsy patients. We aimed to assess the ability of phi to predict prostate cancer (PCa) and high-grade disease (Gleason Score ≥7) on biopsy in a Chinese population. This is a prospective, observational, multi-center study of consecutive patients who underwent a transrectal ultrasound guided prostate biopsy at four hospitals in Shanghai, China from August 2013 to December 2014. In the cohort of 1538 patients, the detection rate of PCa was 40.2%. phi had a significantly better predictive performance for PCa than total PSA (tPSA). The areas under the receiver operating characteristic curve (AUC) were 0.90 and 0.79 for phi and tPSA, respectively, P < 0.0001. A considerable proportion of patients in the cohort had PSAs >10 ng/mL (N = 838, 54.5%). The detection rates of PCa were 35.9% and 57.7% in patients with tPSA 10.1-20 and 20.1-50 ng/mL, respectively. The AUCs of phi (0.79 and 0.89, for these two groups, respectively) were also significantly higher than tPSA (0.57 and 0.63, respectively), both P < 0.0001. If a phi ≤35 was used as the cutoff, 599/1538 (39%) biopsies could have been avoided at a cost of missing small numbers of PCa patients: 49 (7.93%) PCa patients, including 18 (3.69%) high-grade tumors. Results from this study suggest that phi can be used to predict PCa and high-grade disease in Chinese men with high PSA levels (>10 ng/mL). © 2017 Wiley Periodicals, Inc.

Full Life Cycle of Data Analysis with Climate Model Diagnostic Analyzer (CMDA)

NASA Astrophysics Data System (ADS)

Lee, S.; Zhai, C.; Pan, L.; Tang, B.; Zhang, J.; Bao, Q.; Malarout, N.

2017-12-01

We have developed a system that supports the full life cycle of a data analysis process, from data discovery, to data customization, to analysis, to reanalysis, to publication, and to reproduction. The system called Climate Model Diagnostic Analyzer (CMDA) is designed to demonstrate that the full life cycle of data analysis can be supported within one integrated system for climate model diagnostic evaluation with global observational and reanalysis datasets. CMDA has four subsystems that are highly integrated to support the analysis life cycle. Data System manages datasets used by CMDA analysis tools, Analysis System manages CMDA analysis tools which are all web services, Provenance System manages the meta data of CMDA datasets and the provenance of CMDA analysis history, and Recommendation System extracts knowledge from CMDA usage history and recommends datasets/analysis tools to users. These four subsystems are not only highly integrated but also easily expandable. New datasets can be easily added to Data System and scanned to be visible to the other subsystems. New analysis tools can be easily registered to be available in the Analysis System and Provenance System. With CMDA, a user can start a data analysis process by discovering datasets of relevance to their research topic using the Recommendation System. Next, the user can customize the discovered datasets for their scientific use (e.g. anomaly calculation, regridding, etc) with tools in the Analysis System. Next, the user can do their analysis with the tools (e.g. conditional sampling, time averaging, spatial averaging) in the Analysis System. Next, the user can reanalyze the datasets based on the previously stored analysis provenance in the Provenance System. Further, they can publish their analysis process and result to the Provenance System to share with other users. Finally, any user can reproduce the published analysis process and results. By supporting the full life cycle of climate data analysis, CMDA improves the research productivity and collaboration level of its user.

Prognostic Analysis System and Methods of Operation

NASA Technical Reports Server (NTRS)

MacKey, Ryan M. E. (Inventor); Sneddon, Robert (Inventor)

2014-01-01

A prognostic analysis system and methods of operating the system are provided. In particular, a prognostic analysis system for the analysis of physical system health applicable to mechanical, electrical, chemical and optical systems and methods of operating the system are described herein.

Robustness Analysis of Integrated LPV-FDI Filters and LTI-FTC System for a Transport Aircraft

NASA Technical Reports Server (NTRS)

Khong, Thuan H.; Shin, Jong-Yeob

2007-01-01

This paper proposes an analysis framework for robustness analysis of a nonlinear dynamics system that can be represented by a polynomial linear parameter varying (PLPV) system with constant bounded uncertainty. The proposed analysis framework contains three key tools: 1) a function substitution method which can convert a nonlinear system in polynomial form into a PLPV system, 2) a matrix-based linear fractional transformation (LFT) modeling approach, which can convert a PLPV system into an LFT system with the delta block that includes key uncertainty and scheduling parameters, 3) micro-analysis, which is a well known robust analysis tool for linear systems. The proposed analysis framework is applied to evaluating the performance of the LPV-fault detection and isolation (FDI) filters of the closed-loop system of a transport aircraft in the presence of unmodeled actuator dynamics and sensor gain uncertainty. The robustness analysis results are compared with nonlinear time simulations.

System of Systems Analytic Workbench - 2017

DTIC Science & Technology

2017-08-31

and transitional activities with key collaborators. The tools include: System Operational Dependency Analysis/System Developmental Dependency Analysis...in the methods of the SoS-AWB involve the following: 1. System Operability Dependency Analysis (SODA)/System Development Dependency Analysis...available f. Development of standard dependencies with combinations of low-medium-high parameters Report No. SERC-2017-TR-111

Expert systems in civil engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kostem, C.N.; Maher, M.L.

1986-01-01

This book presents the papers given at a symposium on expert systems in civil engineering. Topics considered at the symposium included problem solving using expert system techniques, construction schedule analysis, decision making and risk analysis, seismic risk analysis systems, an expert system for inactive hazardous waste site characterization, an expert system for site selection, knowledge engineering, and knowledge-based expert systems in seismic analysis.

Insight and Evidence Motivating the Simplification of Dual-Analysis Hybrid Systems into Single-Analysis Hybrid Systems

NASA Technical Reports Server (NTRS)

Todling, Ricardo; Diniz, F. L. R.; Takacs, L. L.; Suarez, M. J.

2018-01-01

Many hybrid data assimilation systems currently used for NWP employ some form of dual-analysis system approach. Typically a hybrid variational analysis is responsible for creating initial conditions for high-resolution forecasts, and an ensemble analysis system is responsible for creating sample perturbations used to form the flow-dependent part of the background error covariance required in the hybrid analysis component. In many of these, the two analysis components employ different methodologies, e.g., variational and ensemble Kalman filter. In such cases, it is not uncommon to have observations treated rather differently between the two analyses components; recentering of the ensemble analysis around the hybrid analysis is used to compensated for such differences. Furthermore, in many cases, the hybrid variational high-resolution system implements some type of four-dimensional approach, whereas the underlying ensemble system relies on a three-dimensional approach, which again introduces discrepancies in the overall system. Connected to these is the expectation that one can reliably estimate observation impact on forecasts issued from hybrid analyses by using an ensemble approach based on the underlying ensemble strategy of dual-analysis systems. Just the realization that the ensemble analysis makes substantially different use of observations as compared to their hybrid counterpart should serve as enough evidence of the implausibility of such expectation. This presentation assembles numerous anecdotal evidence to illustrate the fact that hybrid dual-analysis systems must, at the very minimum, strive for consistent use of the observations in both analysis sub-components. Simpler than that, this work suggests that hybrid systems can reliably be constructed without the need to employ a dual-analysis approach. In practice, the idea of relying on a single analysis system is appealing from a cost-maintenance perspective. More generally, single-analysis systems avoid contradictions such as having to choose one sub-component to generate performance diagnostics to another, possibly not fully consistent, component.

14 CFR 417.309 - Flight safety system analysis.

Code of Federal Regulations, 2012 CFR

2012-01-01

... system anomaly occurring and all of its effects as determined by the single failure point analysis and... termination system. (c) Single failure point. A command control system must undergo an analysis that... fault tree analysis or a failure modes effects and criticality analysis; (2) Identify all possible...

14 CFR 417.309 - Flight safety system analysis.

Code of Federal Regulations, 2010 CFR

2010-01-01

... system anomaly occurring and all of its effects as determined by the single failure point analysis and... termination system. (c) Single failure point. A command control system must undergo an analysis that... fault tree analysis or a failure modes effects and criticality analysis; (2) Identify all possible...

14 CFR 417.309 - Flight safety system analysis.

Code of Federal Regulations, 2013 CFR

2013-01-01

... system anomaly occurring and all of its effects as determined by the single failure point analysis and... termination system. (c) Single failure point. A command control system must undergo an analysis that... fault tree analysis or a failure modes effects and criticality analysis; (2) Identify all possible...

14 CFR 417.309 - Flight safety system analysis.

Code of Federal Regulations, 2014 CFR

2014-01-01

... system anomaly occurring and all of its effects as determined by the single failure point analysis and... termination system. (c) Single failure point. A command control system must undergo an analysis that... fault tree analysis or a failure modes effects and criticality analysis; (2) Identify all possible...

14 CFR 417.309 - Flight safety system analysis.

Code of Federal Regulations, 2011 CFR

2011-01-01

... system anomaly occurring and all of its effects as determined by the single failure point analysis and... termination system. (c) Single failure point. A command control system must undergo an analysis that... fault tree analysis or a failure modes effects and criticality analysis; (2) Identify all possible...

Overview of NASA Langley's Systems Analysis Capabilities

NASA Technical Reports Server (NTRS)

Cavanaugh, Stephen; Kumar, Ajay; Brewer, Laura; Kimmel, Bill; Korte, John; Moul, Tom

2006-01-01

The Systems Analysis and Concepts Directorate (SACD) has been in the systems analysis business line supporting National Aeronautics and Space Administration (NASA) aeronautics, exploration, space operations and science since the 1960 s. Our current organization structure is shown in Figure 1. SACD mission can be summed up in the following statements: 1. We conduct advanced concepts for Agency decision makers and programs. 2. We provide aerospace systems analysis products such as mission architectures, advanced system concepts, system and technology trades, life cycle cost and risk analysis, system integration and pre-decisional sensitive information. 3. Our work enables informed technical, programmatic and budgetary decisions. SACD has a complement of 114 government employees and approximately 50 on-site contractors which is equally split between supporting aeronautics and exploration. SACD strives for technical excellence and creditability of the systems analysis products delivered to its customers. The Directorate office is continuously building market intelligence and working with other NASA centers and external partners to expand our business base. The Branches strive for technical excellence and credibility of our systems analysis products by seeking out existing and new partnerships that are critical for successful systems analysis. The Directorates long term goal is to grow the amount of science systems analysis business base.

Systems Analysis and Integration Publications | Transportation Research |

Science.gov Websites

data Vehicle analysis Vehicle energy Vehicle modeling Vehicle simulation Wireless power transfer The NREL Systems Analysis and Integration Publications Systems Analysis and Integration Publications NREL publishes technical reports, fact sheets, and other documents about its systems analysis and

Role of IAC in large space systems thermal analysis

NASA Technical Reports Server (NTRS)

Jones, G. K.; Skladany, J. T.; Young, J. P.

1982-01-01

Computer analysis programs to evaluate critical coupling effects that can significantly influence spacecraft system performance are described. These coupling effects arise from the varied parameters of the spacecraft systems, environments, and forcing functions associated with disciplines such as thermal, structures, and controls. Adverse effects can be expected to significantly impact system design aspects such as structural integrity, controllability, and mission performance. One such needed design analysis capability is a software system that can integrate individual discipline computer codes into a highly user-oriented/interactive-graphics-based analysis capability. The integrated analysis capability (IAC) system can be viewed as: a core framework system which serves as an integrating base whereby users can readily add desired analysis modules and as a self-contained interdisciplinary system analysis capability having a specific set of fully integrated multidisciplinary analysis programs that deal with the coupling of thermal, structures, controls, antenna radiation performance, and instrument optical performance disciplines.

Solar Dynamic Power System Stability Analysis and Control

NASA Technical Reports Server (NTRS)

Momoh, James A.; Wang, Yanchun

1996-01-01

The objective of this research is to conduct dynamic analysis, control design, and control performance test of solar power system. Solar power system consists of generation system and distribution network system. A bench mark system is used in this research, which includes a generator with excitation system and governor, an ac/dc converter, six DDCU's and forty-eight loads. A detailed model is used for modeling generator. Excitation system is represented by a third order model. DDCU is represented by a seventh order system. The load is modeled by the combination of constant power and constant impedance. Eigen-analysis and eigen-sensitivity analysis are used for system dynamic analysis. The effects of excitation system, governor, ac/dc converter control, and the type of load on system stability are discussed. In order to improve system transient stability, nonlinear ac/dc converter control is introduced. The direct linearization method is used for control design. The dynamic analysis results show that these controls affect system stability in different ways. The parameter coordination of controllers are recommended based on the dynamic analysis. It is concluded from the present studies that system stability is improved by the coordination of control parameters and the nonlinear ac/dc converter control stabilize system oscillation caused by the load change and system fault efficiently.

Demonstration Advanced Avionics System (DAAS), Phase 1

NASA Technical Reports Server (NTRS)

Bailey, A. J.; Bailey, D. G.; Gaabo, R. J.; Lahn, T. G.; Larson, J. C.; Peterson, E. M.; Schuck, J. W.; Rodgers, D. L.; Wroblewski, K. A.

1981-01-01

Demonstration advanced anionics system (DAAS) function description, hardware description, operational evaluation, and failure mode and effects analysis (FMEA) are provided. Projected advanced avionics system (PAAS) description, reliability analysis, cost analysis, maintainability analysis, and modularity analysis are discussed.

Tracking and data relay satellite system configuration and tradeoff study, part 1. Volume 3: Telecommunications service system

NASA Technical Reports Server (NTRS)

1972-01-01

The results of the telecommunications subsystem analysis are presented. The relay system requirements and constraints, interference analysis, frequency selection, modulation and coding analysis, and the performance analysis of the relay system are included.

Identification and Analysis of National Airspace System Resource Constraints

NASA Technical Reports Server (NTRS)

Smith, Jeremy C.; Marien, Ty V.; Viken, Jeffery K.; Neitzke, Kurt W.; Kwa, Tech-Seng; Dollyhigh, Samuel M.; Fenbert, James W.; Hinze, Nicolas K.

2015-01-01

This analysis is the deliverable for the Airspace Systems Program, Systems Analysis Integration and Evaluation Project Milestone for the Systems and Portfolio Analysis (SPA) focus area SPA.4.06 Identification and Analysis of National Airspace System (NAS) Resource Constraints and Mitigation Strategies. "Identify choke points in the current and future NAS. Choke points refer to any areas in the en route, terminal, oceanic, airport, and surface operations that constrain actual demand in current and projected future operations. Use the Common Scenarios based on Transportation Systems Analysis Model (TSAM) projections of future demand developed under SPA.4.04 Tools, Methods and Scenarios Development. Analyze causes, including operational and physical constraints." The NASA analysis is complementary to a NASA Research Announcement (NRA) "Development of Tools and Analysis to Evaluate Choke Points in the National Airspace System" Contract # NNA3AB95C awarded to Logistics Management Institute, Sept 2013.

Multidisciplinary Tool for Systems Analysis of Planetary Entry, Descent, and Landing

NASA Technical Reports Server (NTRS)

Samareh, Jamshid A.

2011-01-01

Systems analysis of a planetary entry (SAPE), descent, and landing (EDL) is a multidisciplinary activity in nature. SAPE improves the performance of the systems analysis team by automating and streamlining the process, and this improvement can reduce the errors that stem from manual data transfer among discipline experts. SAPE is a multidisciplinary tool for systems analysis of planetary EDL for Venus, Earth, Mars, Jupiter, Saturn, Uranus, Neptune, and Titan. It performs EDL systems analysis for any planet, operates cross-platform (i.e., Windows, Mac, and Linux operating systems), uses existing software components and open-source software to avoid software licensing issues, performs low-fidelity systems analysis in one hour on a computer that is comparable to an average laptop, and keeps discipline experts in the analysis loop. SAPE uses Python, a platform-independent, open-source language, for integration and for the user interface. Development has relied heavily on the object-oriented programming capabilities that are available in Python. Modules are provided to interface with commercial and government off-the-shelf software components (e.g., thermal protection systems and finite-element analysis). SAPE currently includes the following analysis modules: geometry, trajectory, aerodynamics, aerothermal, thermal protection system, and interface for structural sizing.

Symmetry analysis for hyperbolic equilibria using a TB/dengue fever model

NASA Astrophysics Data System (ADS)

Massoukou, R. Y. M.'Pika; Govinder, K. S.

2016-08-01

We investigate the interplay between Lie symmetry analysis and dynamical systems analysis. As an example, we take a toy model describing the spread of TB and dengue fever. We first undertake a comprehensive dynamical systems analysis including a discussion about local stability. For those regions in which such analyzes cannot be translated to global behavior, we undertake a Lie symmetry analysis. It is shown that the Lie analysis can be useful in providing information for systems where the (local) dynamical systems analysis breaks down.

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Current and advanced act control system definition study. Volume 2: Appendices

NASA Technical Reports Server (NTRS)

Hanks, G. W.; Shomber, H. A.; Dethman, H. A.; Gratzer, L. B.; Maeshiro, A.; Gangsaas, D.; Blight, J. D.; Buchan, S. M.; Crumb, C. B.; Dorwart, R. J.

1981-01-01

The current status of the Active Controls Technology (ACT) for the advanced subsonic transport project is investigated through analysis of the systems technical data. Control systems technologies under examination include computerized reliability analysis, pitch axis fly by wire actuator, flaperon actuation system design trade study, control law synthesis and analysis, flutter mode control and gust load alleviation analysis, and implementation of alternative ACT systems. Extensive analysis of the computer techniques involved in each system is included.

Debugging and Performance Analysis Software Tools for Peregrine System |

Science.gov Websites

High-Performance Computing | NREL Debugging and Performance Analysis Software Tools for Peregrine System Debugging and Performance Analysis Software Tools for Peregrine System Learn about debugging and performance analysis software tools available to use with the Peregrine system. Allinea

Demonstration of a Safety Analysis on a Complex System

NASA Technical Reports Server (NTRS)

Leveson, Nancy; Alfaro, Liliana; Alvarado, Christine; Brown, Molly; Hunt, Earl B.; Jaffe, Matt; Joslyn, Susan; Pinnell, Denise; Reese, Jon; Samarziya, Jeffrey;

Precision Attitude Determination System (PADS) design and analysis. Two-axis gimbal star tracker

NASA Technical Reports Server (NTRS)

1973-01-01

Development of the Precision Attitude Determination System (PADS) focused chiefly on the two-axis gimballed star tracker and electronics design improved from that of Precision Pointing Control System (PPCS), and application of the improved tracker for PADS at geosynchronous altitude. System design, system analysis, software design, and hardware design activities are reported. The system design encompasses the PADS configuration, system performance characteristics, component design summaries, and interface considerations. The PADS design and performance analysis includes error analysis, performance analysis via attitude determination simulation, and star tracker servo design analysis. The design of the star tracker and electronics are discussed. Sensor electronics schematics are included. A detailed characterization of the application software algorithms and computer requirements is provided.

Laser power conversion system analysis, volume 1

NASA Technical Reports Server (NTRS)

Jones, W. S.; Morgan, L. L.; Forsyth, J. B.; Skratt, J. P.

1979-01-01

The orbit-to-orbit laser energy conversion system analysis established a mission model of satellites with various orbital parameters and average electrical power requirements ranging from 1 to 300 kW. The system analysis evaluated various conversion techniques, power system deployment parameters, power system electrical supplies and other critical supplies and other critical subsystems relative to various combinations of the mission model. The analysis show that the laser power system would not be competitive with current satellite power systems from weight, cost and development risk standpoints.

A Behavioral Systems Analysis of Behavior Analysis as a Scientific System

ERIC Educational Resources Information Center

Hayes, Linda J.; Dubuque, Erick M.; Fryling, Mitch J.; Pritchard, Joshua K.

2009-01-01

Behavioral systems analyses typically address organizational problems in business and industry. However, to the extent that a behavioral system is an entity comprised of interdependent elements formed by individuals interacting toward a common goal, a scientific enterprise constitutes a behavioral system to which a behavioral systems analysis may…

The Effect of Online Systems Analysis Training on Aerospace Industry Business Performance: A Qualitative Study

ERIC Educational Resources Information Center

Burk, Erlan

2012-01-01

Aerospace companies needed additional research on technology-based training to verify expectations when enhancing human capital through online systems analysis training. The research for online systems analysis training provided aerospace companies a means to verify expectations for systems analysis technology-based training on business…

21 CFR 874.3310 - Hearing aid calibrator and analysis system.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Hearing aid calibrator and analysis system. 874.3310 Section 874.3310 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... aid calibrator and analysis system. (a) Identification. A hearing aid calibrator and analysis system...

21 CFR 874.3310 - Hearing aid calibrator and analysis system.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Hearing aid calibrator and analysis system. 874.3310 Section 874.3310 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... aid calibrator and analysis system. (a) Identification. A hearing aid calibrator and analysis system...

21 CFR 874.3310 - Hearing aid calibrator and analysis system.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hearing aid calibrator and analysis system. 874.3310 Section 874.3310 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... aid calibrator and analysis system. (a) Identification. A hearing aid calibrator and analysis system...

21 CFR 874.3310 - Hearing aid calibrator and analysis system.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Hearing aid calibrator and analysis system. 874.3310 Section 874.3310 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... aid calibrator and analysis system. (a) Identification. A hearing aid calibrator and analysis system...

21 CFR 874.3310 - Hearing aid calibrator and analysis system.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Hearing aid calibrator and analysis system. 874.3310 Section 874.3310 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... aid calibrator and analysis system. (a) Identification. A hearing aid calibrator and analysis system...

Spacecraft Electrical Power System (EPS) generic analysis tools and techniques

NASA Technical Reports Server (NTRS)

Morris, Gladys M.; Sheppard, Mark A.

1992-01-01

An overview is provided of the analysis tools and techiques used in modeling the Space Station Freedom electrical power system, as well as future space vehicle power systems. The analysis capabilities of the Electrical Power System (EPS) are described and the EPS analysis tools are surveyed.

78 FR 59732 - Revisions to Design of Structures, Components, Equipment, and Systems

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-27

...,'' Section 3.7.2, ``Seismic System Analysis,'' Section 3.7.3, ``Seismic Subsystem Analysis,'' Section 3.8.1... Analysis,'' (Accession No. ML13198A223); Section 3.7.3, ``Seismic Subsystem Analysis,'' (Accession No..., ``Seismic System Analysis,'' Section 3.7.3, ``Seismic Subsystem Analysis,'' Section 3.8.1, ``Concrete...

75 FR 52587 - 2009 Fatality Analysis Reporting System (FARS)/National Automotive Sampling System General...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-26

... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration [U.S. DOT Docket Number NHTSA-2010-0122] 2009 Fatality Analysis Reporting System (FARS)/National Automotive Sampling... Administration (NHTSA)--2009 Fatality Analysis Reporting System (FARS) & National Automotive Sampling System...

A UML Profile for State Analysis

NASA Technical Reports Server (NTRS)

Murray, Alex; Rasmussen, Robert

2010-01-01

State Analysis is a systems engineering methodology for the specification and design of control systems, developed at the Jet Propulsion Laboratory. The methodology emphasizes an analysis of the system under control in terms of States and their properties and behaviors and their effects on each other, a clear separation of the control system from the controlled system, cognizance in the control system of the controlled system's State, goal-based control built on constraining the controlled system's States, and disciplined techniques for State discovery and characterization. State Analysis (SA) introduces two key diagram types: State Effects and Goal Network diagrams. The team at JPL developed a tool for performing State Analysis. The tool includes a drawing capability, backed by a database that supports the diagram types and the organization of the elements of the SA models. But the tool does not support the usual activities of software engineering and design - a disadvantage, since systems to which State Analysis can be applied tend to be very software-intensive. This motivated the work described in this paper: the development of a preliminary Unified Modeling Language (UML) profile for State Analysis. Having this profile would enable systems engineers to specify a system using the methods and graphical language of State Analysis, which is easily linked with a larger system model in SysML (Systems Modeling Language), while also giving software engineers engaged in implementing the specified control system immediate access to and use of the SA model, in the same language, UML, used for other software design. That is, a State Analysis profile would serve as a shared modeling bridge between system and software models for the behavior aspects of the system. This paper begins with an overview of State Analysis and its underpinnings, followed by an overview of the mapping of SA constructs to the UML metamodel. It then delves into the details of these mappings and the constraints associated with them. Finally, we give an example of the use of the profile for expressing an example SA model.

System Analysis in Instructional Programming: The Initial Phases of the Program Construction Process.

ERIC Educational Resources Information Center

Bjerstedt, Ake

A three-volume series describes the construction of a self-instructional system as a work process with three main phases: system analysis, system synthesis, and system modification and evaluation. After an introductory discussion of some basic principles of instructional programing, this first volume focuses on the system analysis phase,…

Development of a sensitivity analysis technique for multiloop flight control systems

NASA Technical Reports Server (NTRS)

Vaillard, A. H.; Paduano, J.; Downing, D. R.

1985-01-01

This report presents the development and application of a sensitivity analysis technique for multiloop flight control systems. This analysis yields very useful information on the sensitivity of the relative-stability criteria of the control system, with variations or uncertainties in the system and controller elements. The sensitivity analysis technique developed is based on the computation of the singular values and singular-value gradients of a feedback-control system. The method is applicable to single-input/single-output as well as multiloop continuous-control systems. Application to sampled-data systems is also explored. The sensitivity analysis technique was applied to a continuous yaw/roll damper stability augmentation system of a typical business jet, and the results show that the analysis is very useful in determining the system elements which have the largest effect on the relative stability of the closed-loop system. As a secondary product of the research reported here, the relative stability criteria based on the concept of singular values were explored.

Systems Analysis for Librarians and Information Professionals. Second Edition. Library and Information Science Text Series.

ERIC Educational Resources Information Center

Osborne, Larry N.; Nakamura, Margaret

This textbook covering the basic techniques of systems analysis targeted to the librarian or information professional contains the following chapters: (1) Understanding Systems Analysis; (2) The Historical Development of Systems Analysis; (3) The Human Element; (4) Identifying and Defining Problems; (5) Collecting Data; (6) Analyzing and…

Large space antennas: A systems analysis case history

NASA Technical Reports Server (NTRS)

Keafer, Lloyd S. (Compiler); Lovelace, U. M. (Compiler)

1987-01-01

The value of systems analysis and engineering is aptly demonstrated by the work on Large Space Antennas (LSA) by the NASA Langley Spacecraft Analysis Branch. This work was accomplished over the last half-decade by augmenting traditional system engineering, analysis, and design techniques with computer-aided engineering (CAE) techniques using the Langley-developed Interactive Design and Evaluation of Advanced Spacecraft (IDEAS) system. This report chronicles the research highlights and special systems analyses that focused the LSA work on deployable truss antennas. It notes developmental trends toward greater use of CAE techniques in their design and analysis. A look to the future envisions the application of improved systems analysis capabilities to advanced space systems such as an advanced space station or to lunar and Martian missions and human habitats.

Motion Analysis System for Instruction of Nihon Buyo using Motion Capture

NASA Astrophysics Data System (ADS)

Shinoda, Yukitaka; Murakami, Shingo; Watanabe, Yuta; Mito, Yuki; Watanuma, Reishi; Marumo, Mieko

The passing on and preserving of advanced technical skills has become an important issue in a variety of fields, and motion analysis using motion capture has recently become popular in the research of advanced physical skills. This research aims to construct a system having a high on-site instructional effect on dancers learning Nihon Buyo, a traditional dance in Japan, and to classify Nihon Buyo dancing according to style, school, and dancer's proficiency by motion analysis. We have been able to study motion analysis systems for teaching Nihon Buyo now that body-motion data can be digitized and stored by motion capture systems using high-performance computers. Thus, with the aim of developing a user-friendly instruction-support system, we have constructed a motion analysis system that displays a dancer's time series of body motions and center of gravity for instructional purposes. In this paper, we outline this instructional motion analysis system based on three-dimensional position data obtained by motion capture. We also describe motion analysis that we performed based on center-of-gravity data obtained by this system and motion analysis focusing on school and age group using this system.

Space Shuttle program communication and tracking systems interface analysis

NASA Technical Reports Server (NTRS)

Dodds, J. G.; Holmes, J. K.; Huth, G. K.; Iwasaki, R. S.; Nilsen, P. W.; Polydoros, A.; Sampaio, D. R.; Udalov, S.

1984-01-01

The Space Shuttle Program Communications and Tracking Systems Interface Analysis began April 18, 1983. During this time, the shuttle communication and tracking systems began flight testing. Two areas of analysis documented were a result of observations made during flight tests. These analyses involved the Ku-band communication system. First, there was a detailed analysis of the interface between the solar max data format and the Ku-band communication system including the TDRSS ground station. The second analysis involving the Ku-band communication system was an analysis of the frequency lock loop of the Gunn oscillator used to generate the transmit frequency. The stability of the frequency lock loop was investigated and changes to the design were reviewed to alleviate the potential loss of data due the loop losing lock and entering the reacquisition mode. Other areas of investigation were the S-band antenna analysis and RF coverage analysis.

Box truss analysis and technology development. Task 1: Mesh analysis and control

NASA Technical Reports Server (NTRS)

Bachtell, E. E.; Bettadapur, S. S.; Coyner, J. V.

1985-01-01

An analytical tool was developed to model, analyze and predict RF performance of box truss antennas with reflective mesh surfaces. The analysis system is unique in that it integrates custom written programs for cord tied mesh surfaces, thereby drastically reducing the cost of analysis. The analysis system is capable of determining the RF performance of antennas under any type of manufacturing or operating environment by integrating together the various disciplines of design, finite element analysis, surface best fit analysis and RF analysis. The Integrated Mesh Analysis System consists of six separate programs: The Mesh Tie System Model Generator, The Loadcase Generator, The Model Optimizer, The Model Solver, The Surface Topography Solver and The RF Performance Solver. Additionally, a study using the mesh analysis system was performed to determine the effect of on orbit calibration, i.e., surface adjustment, on a typical box truss antenna.

14 CFR 25.952 - Fuel system analysis and test.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Powerplant Fuel System § 25.952 Fuel system analysis and test. (a) Proper fuel system functioning under all probable operating conditions must be shown... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Fuel system analysis and test. 25.952...

14 CFR 25.952 - Fuel system analysis and test.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Powerplant Fuel System § 25.952 Fuel system analysis and test. (a) Proper fuel system functioning under all probable operating conditions must be shown... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Fuel system analysis and test. 25.952...

14 CFR 25.952 - Fuel system analysis and test.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Powerplant Fuel System § 25.952 Fuel system analysis and test. (a) Proper fuel system functioning under all probable operating conditions must be shown... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Fuel system analysis and test. 25.952...

14 CFR 25.952 - Fuel system analysis and test.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Powerplant Fuel System § 25.952 Fuel system analysis and test. (a) Proper fuel system functioning under all probable operating conditions must be shown... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Fuel system analysis and test. 25.952...

14 CFR 25.952 - Fuel system analysis and test.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Powerplant Fuel System § 25.952 Fuel system analysis and test. (a) Proper fuel system functioning under all probable operating conditions must be shown... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Fuel system analysis and test. 25.952...

Enhancing TSM&O strategies through life cycle benefit/cost analysis : life cycle benefit/cost analysis & life cycle assessment of adaptive traffic control systems and ramp metering systems.

DOT National Transportation Integrated Search

2015-05-01

The research team developed a comprehensive Benefit/Cost (B/C) analysis framework to evaluate existing and anticipated : intelligent transportation system (ITS) strategies, particularly, adaptive traffic control systems and ramp metering systems, : i...

Energy Analysis Publications | Energy Analysis | NREL

Science.gov Websites

Systems Impact Analysis We perform impact analysis to evaluate and understand the impact of markets publications. Featured Publications Complex Systems Analysis Complex systems analysis integrates all aspects of , policies, and financing on technology uptake and the impact of new technologies on markets and policy

Dynamics analysis of the fast-slow hydro-turbine governing system with different time-scale coupling

NASA Astrophysics Data System (ADS)

Zhang, Hao; Chen, Diyi; Wu, Changzhi; Wang, Xiangyu

2018-01-01

Multi-time scales modeling of hydro-turbine governing system is crucial in precise modeling of hydropower plant and provides support for the stability analysis of the system. Considering the inertia and response time of the hydraulic servo system, the hydro-turbine governing system is transformed into the fast-slow hydro-turbine governing system. The effects of the time-scale on the dynamical behavior of the system are analyzed and the fast-slow dynamical behaviors of the system are investigated with different time-scale. Furthermore, the theoretical analysis of the stable regions is presented. The influences of the time-scale on the stable region are analyzed by simulation. The simulation results prove the correctness of the theoretical analysis. More importantly, the methods and results of this paper provide a perspective to multi-time scales modeling of hydro-turbine governing system and contribute to the optimization analysis and control of the system.

Integrating computer programs for engineering analysis and design

NASA Technical Reports Server (NTRS)

Wilhite, A. W.; Crisp, V. K.; Johnson, S. C.

1983-01-01

The design of a third-generation system for integrating computer programs for engineering and design has been developed for the Aerospace Vehicle Interactive Design (AVID) system. This system consists of an engineering data management system, program interface software, a user interface, and a geometry system. A relational information system (ARIS) was developed specifically for the computer-aided engineering system. It is used for a repository of design data that are communicated between analysis programs, for a dictionary that describes these design data, for a directory that describes the analysis programs, and for other system functions. A method is described for interfacing independent analysis programs into a loosely-coupled design system. This method emphasizes an interactive extension of analysis techniques and manipulation of design data. Also, integrity mechanisms exist to maintain database correctness for multidisciplinary design tasks by an individual or a team of specialists. Finally, a prototype user interface program has been developed to aid in system utilization.

1991 NASA Life Support Systems Analysis workshop

NASA Technical Reports Server (NTRS)

Evanich, Peggy L.; Crabb, Thomas M.; Gartrell, Charles F.

1992-01-01

The 1991 Life Support Systems Analysis Workshop was sponsored by NASA Headquarters' Office of Aeronautics and Space Technology (OAST) to foster communication among NASA, industrial, and academic specialists, and to integrate their inputs and disseminate information to them. The overall objective of systems analysis within the Life Support Technology Program of OAST is to identify, guide the development of, and verify designs which will increase the performance of the life support systems on component, subsystem, and system levels for future human space missions. The specific goals of this workshop were to report on the status of systems analysis capabilities, to integrate the chemical processing industry technologies, and to integrate recommendations for future technology developments related to systems analysis for life support systems. The workshop included technical presentations, discussions, and interactive planning, with time allocated for discussion of both technology status and time-phased technology development recommendations. Key personnel from NASA, industry, and academia delivered inputs and presentations on the status and priorities of current and future systems analysis methods and requirements.

Evaluation of Graph Pattern Matching Workloads in Graph Analysis Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hong, Seokyong; Lee, Sangkeun; Lim, Seung-Hwan

2016-01-01

Graph analysis has emerged as a powerful method for data scientists to represent, integrate, query, and explore heterogeneous data sources. As a result, graph data management and mining became a popular area of research, and led to the development of plethora of systems in recent years. Unfortunately, the number of emerging graph analysis systems and the wide range of applications, coupled with a lack of apples-to-apples comparisons, make it difficult to understand the trade-offs between different systems and the graph operations for which they are designed. A fair comparison of these systems is a challenging task for the following reasons:more » multiple data models, non-standardized serialization formats, various query interfaces to users, and diverse environments they operate in. To address these key challenges, in this paper we present a new benchmark suite by extending the Lehigh University Benchmark (LUBM) to cover the most common capabilities of various graph analysis systems. We provide the design process of the benchmark, which generalizes the workflow for data scientists to conduct the desired graph analysis on different graph analysis systems. Equipped with this extended benchmark suite, we present performance comparison for nine subgraph pattern retrieval operations over six graph analysis systems, namely NetworkX, Neo4j, Jena, Titan, GraphX, and uRiKA. Through the proposed benchmark suite, this study reveals both quantitative and qualitative findings in (1) implications in loading data into each system; (2) challenges in describing graph patterns for each query interface; and (3) different sensitivity of each system to query selectivity. We envision that this study will pave the road for: (i) data scientists to select the suitable graph analysis systems, and (ii) data management system designers to advance graph analysis systems.« less

Research on design connotation of hair drier system

NASA Astrophysics Data System (ADS)

Li, Yongchuan; Wu, Qiong

2018-04-01

After the analysis and summary of the research on the design of hair drier system, the system design is focused on. Product system design is not only to study its entity, but also is recognized as the part, element and component with a systematic feature to deeply analyze the innovation way of product system design, which is taken as its concept to carry out the association analysis on the component elements of hair driers and the overall analysis and study on the system design process of hair dryers. The product life cycle is taken as the main goal, through system analysis, system synthesis and system optimization, to solve the problems of product design. It is of great practical significance.

The environment power system analysis tool development program

NASA Technical Reports Server (NTRS)

Jongeward, Gary A.; Kuharski, Robert A.; Kennedy, Eric M.; Stevens, N. John; Putnam, Rand M.; Roche, James C.; Wilcox, Katherine G.

1990-01-01

The Environment Power System Analysis Tool (EPSAT) is being developed to provide space power system design engineers with an analysis tool for determining system performance of power systems in both naturally occurring and self-induced environments. The program is producing an easy to use computer aided engineering (CAE) tool general enough to provide a vehicle for technology transfer from space scientists and engineers to power system design engineers. The results of the project after two years of a three year development program are given. The EPSAT approach separates the CAE tool into three distinct functional units: a modern user interface to present information, a data dictionary interpreter to coordinate analysis; and a data base for storing system designs and results of analysis.

Interactive Image Analysis System Design,

DTIC Science & Technology

1982-12-01

This report describes a design for an interactive image analysis system (IIAS), which implements terrain data extraction techniques. The design... analysis system. Additionally, the system is fully capable of supporting many generic types of image analysis and data processing, and is modularly...employs commercially available, state of the art minicomputers and image display devices with proven software to achieve a cost effective, reliable image

Application of the Tool for Turbine Engine Closed-loop Transient Analysis (TTECTrA) for Dynamic Systems Analysis

NASA Technical Reports Server (NTRS)

Csank, Jeffrey; Zinnecker, Alicia

2014-01-01

Systems analysis involves steady-state simulations of combined components to evaluate the steady-state performance, weight, and cost of a system; dynamic considerations are not included until later in the design process. The Dynamic Systems Analysis task, under NASAs Fixed Wing project, is developing the capability for assessing dynamic issues at earlier stages during systems analysis. To provide this capability the Tool for Turbine Engine Closed-loop Transient Analysis (TTECTrA) has been developed to design a single flight condition controller (defined as altitude and Mach number) and, ultimately, provide an estimate of the closed-loop performance of the engine model. This tool has been integrated with the Commercial Modular Aero-Propulsion System Simulation 40,000(CMAPSS40k) engine model to demonstrate the additional information TTECTrA makes available for dynamic systems analysis. This dynamic data can be used to evaluate the trade-off between performance and safety, which could not be done with steady-state systems analysis data. TTECTrA has been designed to integrate with any turbine engine model that is compatible with the MATLABSimulink (The MathWorks, Inc.) environment.

Application of the Tool for Turbine Engine Closed-loop Transient Analysis (TTECTrA) for Dynamic Systems Analysis

NASA Technical Reports Server (NTRS)

Csank, Jeffrey Thomas; Zinnecker, Alicia Mae

2014-01-01

Systems analysis involves steady-state simulations of combined components to evaluate the steady-state performance, weight, and cost of a system; dynamic considerations are not included until later in the design process. The Dynamic Systems Analysis task, under NASAs Fixed Wing project, is developing the capability for assessing dynamic issues at earlier stages during systems analysis. To provide this capability the Tool for Turbine Engine Closed-loop Transient Analysis (TTECTrA) has been developed to design a single flight condition controller (defined as altitude and Mach number) and, ultimately, provide an estimate of the closed-loop performance of the engine model. This tool has been integrated with the Commercial Modular Aero-Propulsion System Simulation 40,000 (CMAPSS 40k) engine model to demonstrate the additional information TTECTrA makes available for dynamic systems analysis. This dynamic data can be used to evaluate the trade-off between performance and safety, which could not be done with steady-state systems analysis data. TTECTrA has been designed to integrate with any turbine engine model that is compatible with the MATLAB Simulink (The MathWorks, Inc.) environment.

Medical Image Analysis by Cognitive Information Systems - a Review.

PubMed

Ogiela, Lidia; Takizawa, Makoto

2016-10-01

This publication presents a review of medical image analysis systems. The paradigms of cognitive information systems will be presented by examples of medical image analysis systems. The semantic processes present as it is applied to different types of medical images. Cognitive information systems were defined on the basis of methods for the semantic analysis and interpretation of information - medical images - applied to cognitive meaning of medical images contained in analyzed data sets. Semantic analysis was proposed to analyzed the meaning of data. Meaning is included in information, for example in medical images. Medical image analysis will be presented and discussed as they are applied to various types of medical images, presented selected human organs, with different pathologies. Those images were analyzed using different classes of cognitive information systems. Cognitive information systems dedicated to medical image analysis was also defined for the decision supporting tasks. This process is very important for example in diagnostic and therapy processes, in the selection of semantic aspects/features, from analyzed data sets. Those features allow to create a new way of analysis.

Methodology for object-oriented real-time systems analysis and design: Software engineering

NASA Technical Reports Server (NTRS)

Schoeffler, James D.

1991-01-01

Successful application of software engineering methodologies requires an integrated analysis and design life-cycle in which the various phases flow smoothly 'seamlessly' from analysis through design to implementation. Furthermore, different analysis methodologies often lead to different structuring of the system so that the transition from analysis to design may be awkward depending on the design methodology to be used. This is especially important when object-oriented programming is to be used for implementation when the original specification and perhaps high-level design is non-object oriented. Two approaches to real-time systems analysis which can lead to an object-oriented design are contrasted: (1) modeling the system using structured analysis with real-time extensions which emphasizes data and control flows followed by the abstraction of objects where the operations or methods of the objects correspond to processes in the data flow diagrams and then design in terms of these objects; and (2) modeling the system from the beginning as a set of naturally occurring concurrent entities (objects) each having its own time-behavior defined by a set of states and state-transition rules and seamlessly transforming the analysis models into high-level design models. A new concept of a 'real-time systems-analysis object' is introduced and becomes the basic building block of a series of seamlessly-connected models which progress from the object-oriented real-time systems analysis and design system analysis logical models through the physical architectural models and the high-level design stages. The methodology is appropriate to the overall specification including hardware and software modules. In software modules, the systems analysis objects are transformed into software objects.

Probabilistic structural analysis methods for select space propulsion system components

NASA Technical Reports Server (NTRS)

Millwater, H. R.; Cruse, T. A.

1989-01-01

The Probabilistic Structural Analysis Methods (PSAM) project developed at the Southwest Research Institute integrates state-of-the-art structural analysis techniques with probability theory for the design and analysis of complex large-scale engineering structures. An advanced efficient software system (NESSUS) capable of performing complex probabilistic analysis has been developed. NESSUS contains a number of software components to perform probabilistic analysis of structures. These components include: an expert system, a probabilistic finite element code, a probabilistic boundary element code and a fast probability integrator. The NESSUS software system is shown. An expert system is included to capture and utilize PSAM knowledge and experience. NESSUS/EXPERT is an interactive menu-driven expert system that provides information to assist in the use of the probabilistic finite element code NESSUS/FEM and the fast probability integrator (FPI). The expert system menu structure is summarized. The NESSUS system contains a state-of-the-art nonlinear probabilistic finite element code, NESSUS/FEM, to determine the structural response and sensitivities. A broad range of analysis capabilities and an extensive element library is present.

Constructing a resilience index for the Enhanced Critical Infrastructure Protection Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fisher, R. E.; Bassett, G. W.; Buehring, W. A.

2010-10-14

Following recommendations made in Homeland Security Presidential Directive 7, which established a national policy for the identification and increased protection of critical infrastructure and key resources (CIKR) by Federal departments and agencies, the U.S. Department of Homeland Security (DHS) in 2006 developed the Enhanced Critical Infrastructure Protection (ECIP) program. The ECIP program aimed to provide a closer partnership with state, regional, territorial, local, and tribal authorities in fulfilling the national objective to improve CIKR protection. The program was specifically designed to identify protective measures currently in place in CIKR and to inform facility owners/operators of the benefits of new protectivemore » measures. The ECIP program also sought to enhance existing relationships between DHS and owners/operators of CIKR and to build relationships where none existed (DHS 2008; DHS 2009). In 2009, DHS and its protective security advisors (PSAs) began assessing CIKR assets using the ECIP program and ultimately produced individual protective measure and vulnerability values through the protective measure and vulnerability indices (PMI/VI). The PMI/VI assess the protective measures posture of individual facilities at their 'weakest link,' allowing for a detailed analysis of the most vulnerable aspects of the facilities (Schneier 2003), while maintaining the ability to produce an overall protective measures picture. The PMI has six main components (physical security, security management, security force, information sharing, protective measures assessments, and dependencies) and focuses on actions taken by a facility to prevent or deter the occurrence of an incident (Argonne National Laboratory 2009). As CIKR continue to be assessed using the PMI/VI and owners/operators better understand how they can prevent or deter incidents, academic research, practitioner emphasis, and public policy formation have increasingly focused on resilience as a necessary component of the risk management framework and infrastructure protection. This shift in focus toward resilience complements the analysis of protective measures by taking into account the three other phases of risk management: mitigation, response, and recovery (Figure 1). Thus, the addition of a robust resilience index (RI) to the established PMI/VI provides vital information to owners/operators throughout the risk management process. Combining a pre-incident focus with a better understanding of resilience, as well as potential consequences from damaged CIKR, allows owners/operators to better understand different ways to decrease risk by (1) increasing physical security measures to prevent an incident, (2) supplementing redundancy to mitigate the effects of an incident, and (3) enhancing emergency action and business continuity planning to increase the effectiveness of recovery procedures. Information provided by the RI methodology is also used by facility owners/operators to better understand how their facilities compare to similar sector/subsector sites and to help them make risk-based decisions. This report provides an overview of the RI methodology developed to estimate resilience and provide resilience comparisons for sectors and subsectors. The information will be used to (1) assist DHS in analyzing existing response and recovery methods and programs at facilities and (2) identify potential ways to increase resilience. The RI methodology is based on principles of Appreciative Inquiry, which is 'the coevolutionary search for the best in people, their organizations, and the relevant world around them' (Cooperrider et al. 2005). Appreciative Inquiry identifies the best of 'what is' and helps to envision 'what might be.' The ECIP program and the RI represent a new model (using Appreciative Inquiry principles) for information sharing between government and industry (Fisher and Petit 2010). A 'dashboard' display, which provides an interactive tool - rather than a static report, presents the results of the RI in a convenient format. Additional resilience measures can be modeled to illustrate how such actions would impact the asset's RI value.« less

Analysis of a document/reporting system

NASA Technical Reports Server (NTRS)

Narrow, B.

1971-01-01

An in-depth analysis of the information system within the Data Processing Branch is presented. Quantitative measures are used to evaluate the efficiency and effectiveness of the information system. It is believed that this is the first documented study which utilizes quantitative measures for full scale system analysis. The quantitative measures and techniques for collecting and qualifying the basic data, as described, are applicable to any information system. Therefore this report is considered to be of interest to any persons concerned with the management design, analysis or evaluation of information systems.

Detailed requirements document for the integrated structural analysis system, phase B

NASA Technical Reports Server (NTRS)

Rainey, J. A.

1976-01-01

The requirements are defined for a software system entitled integrated Structural Analysis System (ISAS) Phase B which is being developed to provide the user with a tool by which a complete and detailed analysis of a complex structural system can be performed. This software system will allow for automated interface with numerous structural analysis batch programs and for user interaction in the creation, selection, and validation of data. This system will include modifications to the 4 functions developed for ISAS, and the development of 25 new functions. The new functions are described.

Vibration signature analysis of multistage gear transmission

NASA Technical Reports Server (NTRS)

Choy, F. K.; Tu, Y. K.; Savage, M.; Townsend, D. P.

1989-01-01

An analysis is presented for multistage multimesh gear transmission systems. The analysis predicts the overall system dynamics and the transmissibility to the gear box or the enclosed structure. The modal synthesis approach of the analysis treats the uncoupled lateral/torsional model characteristics of each stage or component independently. The vibration signature analysis evaluates the global dynamics coupling in the system. The method synthesizes the interaction of each modal component or stage with the nonlinear gear mesh dynamics and the modal support geometry characteristics. The analysis simulates transient and steady state vibration events to determine the resulting torque variations, speeds, changes, rotor imbalances, and support gear box motion excitations. A vibration signature analysis examines the overall dynamic characteristics of the system, and the individual model component responses. The gear box vibration analysis also examines the spectral characteristics of the support system.

Standardisation of DNA quantitation by image analysis: quality control of instrumentation.

PubMed

Puech, M; Giroud, F

1999-05-01

DNA image analysis is frequently performed in clinical practice as a prognostic tool and to improve diagnosis. The precision of prognosis and diagnosis depends on the accuracy of analysis and particularly on the quality of image analysis systems. It has been reported that image analysis systems used for DNA quantification differ widely in their characteristics (Thunissen et al.: Cytometry 27: 21-25, 1997). This induces inter-laboratory variations when the same sample is analysed in different laboratories. In microscopic image analysis, the principal instrumentation errors arise from the optical and electronic parts of systems. They bring about problems of instability, non-linearity, and shading and glare phenomena. The aim of this study is to establish tools and standardised quality control procedures for microscopic image analysis systems. Specific reference standard slides have been developed to control instability, non-linearity, shading and glare phenomena and segmentation efficiency. Some systems have been controlled with these tools and these quality control procedures. Interpretation criteria and accuracy limits of these quality control procedures are proposed according to the conclusions of a European project called PRESS project (Prototype Reference Standard Slide). Beyond these limits, tested image analysis systems are not qualified to realise precise DNA analysis. The different procedures presented in this work determine if an image analysis system is qualified to deliver sufficiently precise DNA measurements for cancer case analysis. If the controlled systems are beyond the defined limits, some recommendations are given to find a solution to the problem.

Regional Aquifer-System Analysis Program of the US Geological Survey; bibliography, 1978-86

USGS Publications Warehouse

Weeks, J.B.; Sun, Ren Jen

1987-01-01

The Regional Aquifer-System Analysis Program of the U.S. Geological Survey was initiated in 1978. The purpose of this program is to define the regional geohydrology and establish a framework of background information on geology, hydrology, and geochemistry of the Nation 's important aquifer systems. This information is needed to develop an understanding of the Nation 's major groundwater flow systems and to support better groundwater resources management. As of 1986, investigations of 28 regional aquifer systems were planned, investigations of 9 regional aquifer systems were completed, and 11 regional aquifer systems were being studied. This report is a bibliography of reports completed under the Regional Aquifer-System Analysis Program from 1978 through 1986. The reports resulting from each regional aquifer-system study are listed after an introduction to the study. During 1978-86, 488 reports were completed under the Regional Aquifer-System Analysis Program, and 168 reports which were partially funded by the Regional Aquifer-System Analysis Program were completed under the National Research Program. (Author 's abstract)

Application of structured analysis to a telerobotic system

NASA Technical Reports Server (NTRS)

Dashman, Eric; Mclin, David; Harrison, F. W.; Soloway, Donald; Young, Steven

1990-01-01

The analysis and evaluation of a multiple arm telerobotic research and demonstration system developed by the NASA Intelligent Systems Research Laboratory (ISRL) is described. Structured analysis techniques were used to develop a detailed requirements model of an existing telerobotic testbed. Performance models generated during this process were used to further evaluate the total system. A commercial CASE tool called Teamwork was used to carry out the structured analysis and development of the functional requirements model. A structured analysis and design process using the ISRL telerobotic system as a model is described. Evaluation of this system focused on the identification of bottlenecks in this implementation. The results demonstrate that the use of structured methods and analysis tools can give useful performance information early in a design cycle. This information can be used to ensure that the proposed system meets its design requirements before it is built.

Systemic Analysis Approaches for Air Transportation

NASA Technical Reports Server (NTRS)

Conway, Sheila

2005-01-01

Air transportation system designers have had only limited success using traditional operations research and parametric modeling approaches in their analyses of innovations. They need a systemic methodology for modeling of safety-critical infrastructure that is comprehensive, objective, and sufficiently concrete, yet simple enough to be used with reasonable investment. The methodology must also be amenable to quantitative analysis so issues of system safety and stability can be rigorously addressed. However, air transportation has proven itself an extensive, complex system whose behavior is difficult to describe, no less predict. There is a wide range of system analysis techniques available, but some are more appropriate for certain applications than others. Specifically in the area of complex system analysis, the literature suggests that both agent-based models and network analysis techniques may be useful. This paper discusses the theoretical basis for each approach in these applications, and explores their historic and potential further use for air transportation analysis.

23 CFR 940.11 - Project implementation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... projects funded with highway trust funds shall be based on a systems engineering analysis. (b) The analysis should be on a scale commensurate with the project scope. (c) The systems engineering analysis shall... definitions; (4) Analysis of alternative system configurations and technology options to meet requirements; (5...

23 CFR 940.11 - Project implementation.

Code of Federal Regulations, 2014 CFR

2014-04-01

... projects funded with highway trust funds shall be based on a systems engineering analysis. (b) The analysis should be on a scale commensurate with the project scope. (c) The systems engineering analysis shall... definitions; (4) Analysis of alternative system configurations and technology options to meet requirements; (5...

23 CFR 940.11 - Project implementation.

Code of Federal Regulations, 2012 CFR

2012-04-01

... projects funded with highway trust funds shall be based on a systems engineering analysis. (b) The analysis should be on a scale commensurate with the project scope. (c) The systems engineering analysis shall... definitions; (4) Analysis of alternative system configurations and technology options to meet requirements; (5...

23 CFR 940.11 - Project implementation.

Code of Federal Regulations, 2013 CFR

2013-04-01

... projects funded with highway trust funds shall be based on a systems engineering analysis. (b) The analysis should be on a scale commensurate with the project scope. (c) The systems engineering analysis shall... definitions; (4) Analysis of alternative system configurations and technology options to meet requirements; (5...

23 CFR 940.11 - Project implementation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... projects funded with highway trust funds shall be based on a systems engineering analysis. (b) The analysis should be on a scale commensurate with the project scope. (c) The systems engineering analysis shall... definitions; (4) Analysis of alternative system configurations and technology options to meet requirements; (5...

Coupled dynamics analysis of wind energy systems

NASA Technical Reports Server (NTRS)

Hoffman, J. A.

1977-01-01

A qualitative description of all key elements of a complete wind energy system computer analysis code is presented. The analysis system addresses the coupled dynamics characteristics of wind energy systems, including the interactions of the rotor, tower, nacelle, power train, control system, and electrical network. The coupled dynamics are analyzed in both the frequency and time domain to provide the basic motions and loads data required for design, performance verification and operations analysis activities. Elements of the coupled analysis code were used to design and analyze candidate rotor articulation concepts. Fundamental results and conclusions derived from these studies are presented.

New multivariable capabilities of the INCA program

NASA Technical Reports Server (NTRS)

Bauer, Frank H.; Downing, John P.; Thorpe, Christopher J.

1989-01-01

The INteractive Controls Analysis (INCA) program was developed at NASA's Goddard Space Flight Center to provide a user friendly, efficient environment for the design and analysis of control systems, specifically spacecraft control systems. Since its inception, INCA has found extensive use in the design, development, and analysis of control systems for spacecraft, instruments, robotics, and pointing systems. The (INCA) program was initially developed as a comprehensive classical design analysis tool for small and large order control systems. The latest version of INCA, expected to be released in February of 1990, was expanded to include the capability to perform multivariable controls analysis and design.

Causal inference in nonlinear systems: Granger causality versus time-delayed mutual information

NASA Astrophysics Data System (ADS)

Li, Songting; Xiao, Yanyang; Zhou, Douglas; Cai, David

2018-05-01

The Granger causality (GC) analysis has been extensively applied to infer causal interactions in dynamical systems arising from economy and finance, physics, bioinformatics, neuroscience, social science, and many other fields. In the presence of potential nonlinearity in these systems, the validity of the GC analysis in general is questionable. To illustrate this, here we first construct minimal nonlinear systems and show that the GC analysis fails to infer causal relations in these systems—it gives rise to all types of incorrect causal directions. In contrast, we show that the time-delayed mutual information (TDMI) analysis is able to successfully identify the direction of interactions underlying these nonlinear systems. We then apply both methods to neuroscience data collected from experiments and demonstrate that the TDMI analysis but not the GC analysis can identify the direction of interactions among neuronal signals. Our work exemplifies inference hazards in the GC analysis in nonlinear systems and suggests that the TDMI analysis can be an appropriate tool in such a case.

48 CFR 215.404 - Proposal analysis.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Proposal analysis. 215.404 Section 215.404 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Proposal analysis. ...

48 CFR 215.404 - Proposal analysis.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Proposal analysis. 215.404 Section 215.404 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Proposal analysis. ...

Fast Computation and Assessment Methods in Power System Analysis

NASA Astrophysics Data System (ADS)

Nagata, Masaki

Power system analysis is essential for efficient and reliable power system operation and control. Recently, online security assessment system has become of importance, as more efficient use of power networks is eagerly required. In this article, fast power system analysis techniques such as contingency screening, parallel processing and intelligent systems application are briefly surveyed from the view point of their application to online dynamic security assessment.

First On-Site Data Analysis System for Subaru/Suprime-Cam

NASA Astrophysics Data System (ADS)

Furusawa, Hisanori; Okura, Yuki; Mineo, Sogo; Takata, Tadafumi; Nakata, Fumiaki; Tanaka, Manobu; Katayama, Nobuhiko; Itoh, Ryosuke; Yasuda, Naoki; Miyazaki, Satoshi; Komiyama, Yutaka; Utsumi, Yousuke; Uchida, Tomohisa; Aihara, Hiroaki

2011-03-01

We developed an automated on-site quick analysis system for mosaic CCD data of Suprime-Cam, which is a wide-field camera mounted at the prime focus of the Subaru Telescope, Mauna Kea, Hawaii. The first version of the data-analysis system was constructed, and started to operate in general observations. This system is a new function of observing support at the Subaru Telescope to provide the Subaru user community with an automated on-site data evaluation, aiming at improvements of observers' productivity, especially in large imaging surveys. The new system assists the data evaluation tasks in observations by the continuous monitoring of the characteristics of every data frame during observations. The evaluation results and data frames processed by this system are also useful for reducing the data-processing time in a full analysis after an observation. The primary analysis functions implemented in the data-analysis system are composed of automated realtime analysis for data evaluation and on-demand analysis, which is executed upon request, including mosaicing analysis and flat making analysis. In data evaluation, which is controlled by the organizing software, the database keeps track of the analysis histories, as well as the evaluated values of data frames, including seeing and sky background levels; it also helps in the selection of frames for mosaicing and flat making analysis. We examined the system performance and confirmed an improvement in the data-processing time by a factor of 9 with the aid of distributed parallel data processing and on-memory data processing, which makes the automated data evaluation effective.

Behavior Analysis in Distance Education: A Systems Approach.

ERIC Educational Resources Information Center

Coldeway, Dan O.

1987-01-01

Describes a model of instructional theory relevant to individualized distance education that is based on Keller's Personalized System of Instruction (PSI), behavior analysis, and the instructional systems development model (ISD). Systems theory is emphasized, and ISD and behavior analysis are discussed as cybernetic processes. (LRW)

Requirements Analysis for Information-Intensive Systems

NASA Technical Reports Server (NTRS)

Callender, E. D.; Hartsough, C.; Morris, R. V.; Yamamoto, Y.

1986-01-01

Report discusses role of requirements analysis in development of information-intensive systems. System examined from variety of human viewpoints during design, development, and implementation. Such examination, called requirements analysis, ensures system simultaneously meets number of distinct but interacting needs. Viewpoints defined and integrated to help attain objectives.

A Mapping from the Human Factors Analysis and Classification System (DOD-HFACS) to the Domains of Human Systems Integration (HSI)

DTIC Science & Technology

2009-11-01

Equation Chapter 1 Section 1 A MAPPING FROM THE HUMAN FACTORS ANALYSIS AND CLASSIFICATION SYSTEM (DOD...OMB control number. 1. REPORT DATE NOV 2009 2. REPORT TYPE 3. DATES COVERED 4. TITLE AND SUBTITLE A Mapping from the Human Factors Analysis ...7 The Human Factors Analysis and Classification System .................................................. 7 Mapping of DoD

Model-Based Safety Analysis

NASA Technical Reports Server (NTRS)

Joshi, Anjali; Heimdahl, Mats P. E.; Miller, Steven P.; Whalen, Mike W.

2006-01-01

System safety analysis techniques are well established and are used extensively during the design of safety-critical systems. Despite this, most of the techniques are highly subjective and dependent on the skill of the practitioner. Since these analyses are usually based on an informal system model, it is unlikely that they will be complete, consistent, and error free. In fact, the lack of precise models of the system architecture and its failure modes often forces the safety analysts to devote much of their effort to gathering architectural details about the system behavior from several sources and embedding this information in the safety artifacts such as the fault trees. This report describes Model-Based Safety Analysis, an approach in which the system and safety engineers share a common system model created using a model-based development process. By extending the system model with a fault model as well as relevant portions of the physical system to be controlled, automated support can be provided for much of the safety analysis. We believe that by using a common model for both system and safety engineering and automating parts of the safety analysis, we can both reduce the cost and improve the quality of the safety analysis. Here we present our vision of model-based safety analysis and discuss the advantages and challenges in making this approach practical.

System Analysis Applied to Autonomy: Application to High-Altitude Long-Endurance Remotely Operated Aircraft

NASA Technical Reports Server (NTRS)

Young, Larry A.; Yetter, Jeffrey A.; Guynn, Mark D.

2006-01-01

Maturation of intelligent systems technologies and their incorporation into aerial platforms are dictating the development of new analysis tools and incorporation of such tools into existing system analysis methodologies in order to fully capture the trade-offs of autonomy on vehicle and mission success. A first-order "system analysis of autonomy" methodology is outlined in this paper. Further, this analysis methodology is subsequently applied to notional high-altitude long-endurance (HALE) aerial vehicle missions.

Economic analysis of the space shuttle system, volume 1

NASA Technical Reports Server (NTRS)

1972-01-01

An economic analysis of the space shuttle system is presented. The analysis is based on economic benefits, recurring costs, non-recurring costs, and ecomomic tradeoff functions. The most economic space shuttle configuration is determined on the basis of: (1) objectives of reusable space transportation system, (2) various space transportation systems considered and (3) alternative space shuttle systems.

Critical Education for Systemic Change: A World-Systems Analysis Perspective

ERIC Educational Resources Information Center

Griffiths, Tom G.

2015-01-01

This paper both draws on, and seeks to apply, world-systems analysis to a broad, critical education project that builds mass schooling's potential contribution to the process of world-systemic change. In short, this is done by first setting out the world-systems analysis account of the current state, and period of transition, of the capitalist…

A Preliminary Study on Gender Differences in Studying Systems Analysis and Design

ERIC Educational Resources Information Center

Lee, Fion S. L.; Wong, Kelvin C. K.

2017-01-01

Systems analysis and design is a crucial task in system development and is included in a typical information systems programme as a core course. This paper presented a preliminary study on gender differences in studying a systems analysis and design course of an undergraduate programme. Results indicated that male students outperformed female…

Evidential Reasoning in Expert Systems for Image Analysis.

DTIC Science & Technology

1985-02-01

techniques to image analysis (IA). There is growing evidence that these techniques offer significant improvements in image analysis , particularly in the...2) to provide a common framework for analysis, (3) to structure the ER process for major expert-system tasks in image analysis , and (4) to identify...approaches to three important tasks for expert systems in the domain of image analysis . This segment concluded with an assessment of the strengths

SEU System Analysis: Not Just the Sum of All Parts

NASA Technical Reports Server (NTRS)

Berg, Melanie D.; Label, Kenneth

2014-01-01

Single event upset (SEU) analysis of complex systems is challenging. Currently, system SEU analysis is performed by component level partitioning and then either: the most dominant SEU cross-sections (SEUs) are used in system error rate calculations; or the partition SEUs are summed to eventually obtain a system error rate. In many cases, system error rates are overestimated because these methods generally overlook system level derating factors. The problem with overestimating is that it can cause overdesign and consequently negatively affect the following: cost, schedule, functionality, and validation/verification. The scope of this presentation is to discuss the risks involved with our current scheme of SEU analysis for complex systems; and to provide alternative methods for improvement.

A performance analysis method for distributed real-time robotic systems: A case study of remote teleoperation

NASA Technical Reports Server (NTRS)

Lefebvre, D. R.; Sanderson, A. C.

1994-01-01

Robot coordination and control systems for remote teleoperation applications are by necessity implemented on distributed computers. Modeling and performance analysis of these distributed robotic systems is difficult, but important for economic system design. Performance analysis methods originally developed for conventional distributed computer systems are often unsatisfactory for evaluating real-time systems. The paper introduces a formal model of distributed robotic control systems; and a performance analysis method, based on scheduling theory, which can handle concurrent hard-real-time response specifications. Use of the method is illustrated by a case of remote teleoperation which assesses the effect of communication delays and the allocation of robot control functions on control system hardware requirements.

75 FR 60493 - Advisory Circular 120-79A, Developing and Implementing an Air Carrier Continuing Analysis and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-30

... and Implementing an Air Carrier Continuing Analysis and Surveillance System AGENCY: Federal Aviation... Analysis and Surveillance System''. This new advisory circular (AC) updates AC 120-79 originally issued on... Analysis and Surveillance System (CASS) required for commercial operators and air carriers certificated...

System Analysis Applied to Autonomy: Application to Human-Rated Lunar/Mars Landers

NASA Technical Reports Server (NTRS)

Young, Larry A.

2006-01-01

System analysis is an essential technical discipline for the modern design of spacecraft and their associated missions. Specifically, system analysis is a powerful aid in identifying and prioritizing the required technologies needed for mission and/or vehicle development efforts. Maturation of intelligent systems technologies, and their incorporation into spacecraft systems, are dictating the development of new analysis tools, and incorporation of such tools into existing system analysis methodologies, in order to fully capture the trade-offs of autonomy on vehicle and mission success. A "system analysis of autonomy" methodology will be outlined and applied to a set of notional human-rated lunar/Mars lander missions toward answering these questions: 1. what is the optimum level of vehicle autonomy and intelligence required? and 2. what are the specific attributes of an autonomous system implementation essential for a given surface lander mission/application in order to maximize mission success? Future human-rated lunar/Mars landers, though nominally under the control of their crew, will, nonetheless, be highly automated systems. These automated systems will range from mission/flight control functions, to vehicle health monitoring and prognostication, to life-support and other "housekeeping" functions. The optimum degree of autonomy afforded to these spacecraft systems/functions has profound implications from an exploration system architecture standpoint.

Systems thinking, the Swiss Cheese Model and accident analysis: a comparative systemic analysis of the Grayrigg train derailment using the ATSB, AcciMap and STAMP models.

PubMed

Underwood, Peter; Waterson, Patrick

2014-07-01

The Swiss Cheese Model (SCM) is the most popular accident causation model and is widely used throughout various industries. A debate exists in the research literature over whether the SCM remains a viable tool for accident analysis. Critics of the model suggest that it provides a sequential, oversimplified view of accidents. Conversely, proponents suggest that it embodies the concepts of systems theory, as per the contemporary systemic analysis techniques. The aim of this paper was to consider whether the SCM can provide a systems thinking approach and remain a viable option for accident analysis. To achieve this, the train derailment at Grayrigg was analysed with an SCM-based model (the ATSB accident investigation model) and two systemic accident analysis methods (AcciMap and STAMP). The analysis outputs and usage of the techniques were compared. The findings of the study showed that each model applied the systems thinking approach. However, the ATSB model and AcciMap graphically presented their findings in a more succinct manner, whereas STAMP more clearly embodied the concepts of systems theory. The study suggests that, whilst the selection of an analysis method is subject to trade-offs that practitioners and researchers must make, the SCM remains a viable model for accident analysis. Copyright © 2013 Elsevier Ltd. All rights reserved.

Multisensor Image Analysis System

DTIC Science & Technology

1993-04-15

AD-A263 679 II Uli! 91 Multisensor Image Analysis System Final Report Authors. Dr. G. M. Flachs Dr. Michael Giles Dr. Jay Jordan Dr. Eric...or decision, unless so designated by other documentation. 93-09739 *>ft s n~. now illlllM3lMVf Multisensor Image Analysis System Final...Multisensor Image Analysis System 3. REPORT TYPE AND DATES COVERED FINAL: LQj&tt-Z JZOfVL 5. FUNDING NUMBERS 93 > 6. AUTHOR(S) Drs. Gerald

TADS--A CFD-Based Turbomachinery Analysis and Design System with GUI: User's Manual. 2.0

NASA Technical Reports Server (NTRS)

Koiro, M. J.; Myers, R. A.; Delaney, R. A.

1999-01-01

The primary objective of this study was the development of a Computational Fluid Dynamics (CFD) based turbomachinery airfoil analysis and design system, controlled by a Graphical User Interface (GUI). The computer codes resulting from this effort are referred to as TADS (Turbomachinery Analysis and Design System). This document is intended to serve as a User's Manual for the computer programs which comprise the TADS system, developed under Task 18 of NASA Contract NAS3-27350, ADPAC System Coupling to Blade Analysis & Design System GUI and Task 10 of NASA Contract NAS3-27394, ADPAC System Coupling to Blade Analysis & Design System GUI, Phase II-Loss, Design and, Multi-stage Analysis. TADS couples a throughflow solver (ADPAC) with a quasi-3D blade-to-blade solver (RVCQ3D) in an interactive package. Throughflow analysis and design capability was developed in ADPAC through the addition of blade force and blockage terms to the governing equations. A GUI was developed to simplify user input and automate the many tasks required to perform turbomachinery analysis and design. The coupling of the various programs was done in such a way that alternative solvers or grid generators could be easily incorporated into the TADS framework. Results of aerodynamic calculations using the TADS system are presented for a highly loaded fan, a compressor stator, a low speed turbine blade and a transonic turbine vane.

Systems Analysis and Design: Know Your Audience

ERIC Educational Resources Information Center

Reinicke, Bryan A.

2012-01-01

Systems analysis and design (SAD) classes are required in both Information Systems and Accounting programs, but these audiences have very different needs for these skills. This article will review the requirements for SAD within each of these disciplines and compare and contrast the different requirements for teaching systems analysis and design…

Relaxation mode analysis of a peptide system: comparison with principal component analysis.

PubMed

Mitsutake, Ayori; Iijima, Hiromitsu; Takano, Hiroshi

2011-10-28

This article reports the first attempt to apply the relaxation mode analysis method to a simulation of a biomolecular system. In biomolecular systems, the principal component analysis is a well-known method for analyzing the static properties of fluctuations of structures obtained by a simulation and classifying the structures into some groups. On the other hand, the relaxation mode analysis has been used to analyze the dynamic properties of homopolymer systems. In this article, a long Monte Carlo simulation of Met-enkephalin in gas phase has been performed. The results are analyzed by the principal component analysis and relaxation mode analysis methods. We compare the results of both methods and show the effectiveness of the relaxation mode analysis.

Analysis and design of a capsule landing system and surface vehicle control system for Mars exploration

NASA Technical Reports Server (NTRS)

1974-01-01

A number of problems related to the design, construction and evaluation of an autonomous roving planetary vehicle and its control and operating systems intended for an unmanned exploration of Mars are studied. Vehicle configuration, dynamics, control, systems and propulsion; systems analysis; terrain sensing and modeling and path selection; and chemical analysis of samples are included.

Application Research of Fault Tree Analysis in Grid Communication System Corrective Maintenance

NASA Astrophysics Data System (ADS)

Wang, Jian; Yang, Zhenwei; Kang, Mei

2018-01-01

This paper attempts to apply the fault tree analysis method to the corrective maintenance field of grid communication system. Through the establishment of the fault tree model of typical system and the engineering experience, the fault tree analysis theory is used to analyze the fault tree model, which contains the field of structural function, probability importance and so on. The results show that the fault tree analysis can realize fast positioning and well repairing of the system. Meanwhile, it finds that the analysis method of fault tree has some guiding significance to the reliability researching and upgrading f the system.

A computer-aided movement analysis system.

PubMed

Fioretti, S; Leo, T; Pisani, E; Corradini, M L

1990-08-01

Interaction with biomechanical data concerning human movement analysis implies the adoption of various experimental equipments and the choice of suitable models, data processing, and graphical data restitution techniques. The integration of measurement setups with the associated experimental protocols and the relative software procedures constitutes a computer-aided movement analysis (CAMA) system. In the present paper such integration is mapped onto the causes that limit the clinical acceptance of movement analysis methods. The structure of the system is presented. A specific CAMA system devoted to posture analysis is described in order to show the attainable features. Scientific results obtained with the support of the described system are also reported.

Digital processing of mesoscale analysis and space sensor data

NASA Technical Reports Server (NTRS)

Hickey, J. S.; Karitani, S.

1985-01-01

The mesoscale analysis and space sensor (MASS) data management and analysis system on the research computer system is presented. The MASS data base management and analysis system was implemented on the research computer system which provides a wide range of capabilities for processing and displaying large volumes of conventional and satellite derived meteorological data. The research computer system consists of three primary computers (HP-1000F, Harris/6, and Perkin-Elmer 3250), each of which performs a specific function according to its unique capabilities. The overall tasks performed concerning the software, data base management and display capabilities of the research computer system in terms of providing a very effective interactive research tool for the digital processing of mesoscale analysis and space sensor data is described.

Airport Surface Control Systems Development Analysis Expanded

DOT National Transportation Integrated Search

1990-01-01

A previous MITRE Technical Report, Airport Surface Traffic Control Systems Deployment Analysis, FAA-RD-74-6, presented an analysis of ASTC (Airport Surface Traffic Control) system requirements and developed estimates of the deployment potential of pr...

Used Nuclear Fuel-Storage, Transportation & Disposal Analysis Resource and Data System (UNF-ST&DARDS)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Banerjee, Kaushik; Clarity, Justin B; Cumberland, Riley M

This will be licensed via RSICC. A new, integrated data and analysis system has been designed to simplify and automate the performance of accurate and efficient evaluations for characterizing the input to the overall nuclear waste management system -UNF-Storage, Transportation & Disposal Analysis Resource and Data System (UNF-ST&DARDS). A relational database within UNF-ST&DARDS provides a standard means by which UNF-ST&DARDS can succinctly store and retrieve modeling and simulation (M&S) parameters for specific spent nuclear fuel analysis. A library of various analysis model templates provides the ability to communicate the various set of M&S parameters to the most appropriate M&S application.more » Interactive visualization capabilities facilitate data analysis and results interpretation. UNF-ST&DARDS current analysis capabilities include (1) assembly-specific depletion and decay, (2) and spent nuclear fuel cask-specific criticality and shielding. Currently, UNF-ST&DARDS uses SCALE nuclear analysis code system for performing nuclear analysis.« less

Study of aircraft in intraurban transportation systems, volume 1

NASA Technical Reports Server (NTRS)

Stout, E. G.; Kesling, P. H.; Matteson, H. C.; Sherwood, D. E.; Tuck, W. R., Jr.; Vaughn, L. A.

1971-01-01

An analysis of an effective short range, high density computer transportation system for intraurban systems is presented. The seven county Detroit, Michigan, metropolitan area, was chosen as the scenario for the analysis. The study consisted of an analysis and forecast of the Detroit market through 1985, a parametric analysis of appropriate short haul aircraft concepts and associated ground systems, and a preliminary overall economic analysis of a simplified total system designed to evaluate the candidate vehicles and select the most promising VTOL and STOL aircraft. Data are also included on the impact of advanced technology on the system, the sensitivity of mission performance to changes in aircraft characteristics and system operations, and identification of key problem areas that may be improved by additional research. The approach, logic, and computer models used are adaptable to other intraurban or interurban areas.

DISPLA: decision information system for procurement and logistics analysis

NASA Astrophysics Data System (ADS)

Calvo, Alberto B.; Danish, Alexander J.; Lamonakis, Gregory G.

2002-08-01

This paper describes an information-exchange system for Display systems acquisition and logistics support. DISPLA (Decision Information System for Procurement and Logistics Analysis) is an Internet-based system concept for bringing sellers (display system and component suppliers) and buyers (Government Program Offices and System Integrators) together in an electronic exchange to improve the acquisition and logistics analysis support of Flat Panel Displays for the military. A proof-of-concept demonstration is presented in this paper using sample data from vendor Web sites and Government data sources.

Probabilistic Parameter Uncertainty Analysis of Single Input Single Output Control Systems

NASA Technical Reports Server (NTRS)

Smith, Brett A.; Kenny, Sean P.; Crespo, Luis G.

2005-01-01

The current standards for handling uncertainty in control systems use interval bounds for definition of the uncertain parameters. This approach gives no information about the likelihood of system performance, but simply gives the response bounds. When used in design, current methods of m-analysis and can lead to overly conservative controller design. With these methods, worst case conditions are weighted equally with the most likely conditions. This research explores a unique approach for probabilistic analysis of control systems. Current reliability methods are examined showing the strong areas of each in handling probability. A hybrid method is developed using these reliability tools for efficiently propagating probabilistic uncertainty through classical control analysis problems. The method developed is applied to classical response analysis as well as analysis methods that explore the effects of the uncertain parameters on stability and performance metrics. The benefits of using this hybrid approach for calculating the mean and variance of responses cumulative distribution functions are shown. Results of the probabilistic analysis of a missile pitch control system, and a non-collocated mass spring system, show the added information provided by this hybrid analysis.

Optimal subinterval selection approach for power system transient stability simulation

DOE PAGES

Kim, Soobae; Overbye, Thomas J.

2015-10-21

Power system transient stability analysis requires an appropriate integration time step to avoid numerical instability as well as to reduce computational demands. For fast system dynamics, which vary more rapidly than what the time step covers, a fraction of the time step, called a subinterval, is used. However, the optimal value of this subinterval is not easily determined because the analysis of the system dynamics might be required. This selection is usually made from engineering experiences, and perhaps trial and error. This paper proposes an optimal subinterval selection approach for power system transient stability analysis, which is based on modalmore » analysis using a single machine infinite bus (SMIB) system. Fast system dynamics are identified with the modal analysis and the SMIB system is used focusing on fast local modes. An appropriate subinterval time step from the proposed approach can reduce computational burden and achieve accurate simulation responses as well. As a result, the performance of the proposed method is demonstrated with the GSO 37-bus system.« less

The ALICE analysis train system

NASA Astrophysics Data System (ADS)

Zimmermann, Markus; ALICE Collaboration

2015-05-01

In the ALICE experiment hundreds of users are analyzing big datasets on a Grid system. High throughput and short turn-around times are achieved by a centralized system called the LEGO trains. This system combines analysis from different users in so-called analysis trains which are then executed within the same Grid jobs thereby reducing the number of times the data needs to be read from the storage systems. The centralized trains improve the performance, the usability for users and the bookkeeping in comparison to single user analysis. The train system builds upon the already existing ALICE tools, i.e. the analysis framework as well as the Grid submission and monitoring infrastructure. The entry point to the train system is a web interface which is used to configure the analysis and the desired datasets as well as to test and submit the train. Several measures have been implemented to reduce the time a train needs to finish and to increase the CPU efficiency.

Systems-Dynamic Analysis for Neighborhood Study

EPA Science Inventory

Systems-dynamic analysis (or system dynamics (SD)) helps planners identify interrelated impacts of transportation and land-use policies on neighborhood-scale economic outcomes for households and businesses, among other applications. This form of analysis can show benefits and tr...

Comparison of Building Loads Analysis and System Thermodynamics (BLAST) Computer Program Simulations and Measured Energy Use for Army Buildings.

DTIC Science & Technology

1980-05-01

engineering ,ZteNo D R RPTE16 research w 9 laboratory COMPARISON OF BUILDING LOADS ANALYSIS AND SYSTEM THERMODYNAMICS (BLAST) AD 0 5 5,0 3COMPUTER PROGRAM...Building Loads Analysis and System Thermodynamics (BLAST) computer program. A dental clinic and a battalion headquarters and classroom building were...Building and HVAC System Data Computer Simulation Comparison of Actual and Simulated Results ANALYSIS AND FINDINGS

Reliability Analysis of the Space Station Freedom Electrical Power System

DTIC Science & Technology

1989-08-01

Cleveland, Ohio, who assisted in obtaining related research materials and provided feedback on our efforts to produce a dynamic analysis tool useful to...System software that we used to do our analysis of the electrical power system. Thanks are due to Dr. Vira Chankong, my thesis advisor, for his...a frequency duration analysis . Using a transition rate matrix with a model of the photovoltaic and solar dynamic systems, they have one model that

Integrated analysis of large space systems

NASA Technical Reports Server (NTRS)

Young, J. P.

1980-01-01

Based on the belief that actual flight hardware development of large space systems will necessitate a formalized method of integrating the various engineering discipline analyses, an efficient highly user oriented software system capable of performing interdisciplinary design analyses with tolerable solution turnaround time is planned Specific analysis capability goals were set forth with initial emphasis given to sequential and quasi-static thermal/structural analysis and fully coupled structural/control system analysis. Subsequently, the IAC would be expanded to include a fully coupled thermal/structural/control system, electromagnetic radiation, and optical performance analyses.

Precision Attitude Determination System (PADS) system design and analysis: Single-axis gimbal star tracker

NASA Technical Reports Server (NTRS)

1974-01-01

The feasibility is evaluated of an evolutionary development for use of a single-axis gimbal star tracker from prior two-axis gimbal star tracker based system applications. Detailed evaluation of the star tracker gimbal encoder is considered. A brief system description is given including the aspects of tracker evolution and encoder evaluation. System analysis includes evaluation of star availability and mounting constraints for the geosynchronous orbit application, and a covariance simulation analysis to evaluate performance potential. Star availability and covariance analysis digital computer programs are included.

Lightweight Towed Howitzer Demonstrator. Phase 1 and Partial Phase 2. Volume D3. Part 1. Structural Analysis of System.

DTIC Science & Technology

1987-04-01

Volume D3 - Part I Structural Analysis of System DTIC ELECTE a MApril 1987 SE 03 O0 Contract Number DAAA21-86-C-0047 FMC CORPORATION Northern Ordnance... system , In turn. facilitated crew reductilon via hydraulic emplacement, .four-way Joystick tube- lay, and _power ralming. . MC completed C;oncep)t...D3 Structural Analysis of System PART I D3/050 Table of Contents D3/100 Structural Analysis of SystemUD3/110 CXL Memo: October 3, 1986 D3/120 o

Natural Resource Information System, design analysis

NASA Technical Reports Server (NTRS)

1972-01-01

The computer-based system stores, processes, and displays map data relating to natural resources. The system was designed on the basis of requirements established in a user survey and an analysis of decision flow. The design analysis effort is described, and the rationale behind major design decisions, including map processing, cell vs. polygon, choice of classification systems, mapping accuracy, system hardware, and software language is summarized.

Testing a Wheeled Landing Gear System for the TH-57 Helicopter

DTIC Science & Technology

1992-12-01

initial comparison was done using a structural analysis program, GIFTS , to simultaneously analyze an~i compare the gear systems. Experimental data was used...15 B. GIFTS PROGRAM RESULTS ............................ 15 1. Model...Element Total System ( GIFTS ) structural analysis program, which is resident oin the Aeiunauimia Euginme1ing Department computer system, an analysis

Dynamic Systems Analysis for Turbine Based Aero Propulsion Systems

NASA Technical Reports Server (NTRS)

Csank, Jeffrey T.

2016-01-01

The aircraft engine design process seeks to optimize the overall system-level performance, weight, and cost for a given concept. Steady-state simulations and data are used to identify trade-offs that should be balanced to optimize the system in a process known as systems analysis. These systems analysis simulations and data may not adequately capture the true performance trade-offs that exist during transient operation. Dynamic systems analysis provides the capability for assessing the dynamic tradeoffs at an earlier stage of the engine design process. The dynamic systems analysis concept, developed tools, and potential benefit are presented in this paper. To provide this capability, the Tool for Turbine Engine Closed-loop Transient Analysis (TTECTrA) was developed to provide the user with an estimate of the closed-loop performance (response time) and operability (high pressure compressor surge margin) for a given engine design and set of control design requirements. TTECTrA along with engine deterioration information, can be used to develop a more generic relationship between performance and operability that can impact the engine design constraints and potentially lead to a more efficient engine.

ISTAR: Intelligent System for Telemetry Analysis in Real-time

NASA Technical Reports Server (NTRS)

Simmons, Charles

1994-01-01

The intelligent system for telemetry analysis in real-time (ISTAR) is an advanced vehicle monitoring environment incorporating expert systems, analysis tools, and on-line hypermedia documentation. The system was developed for the Air Force Space and Missile Systems Center (SMC) in Los Angeles, California, in support of the inertial upper stage (IUS) booster vehicle. Over a five year period the system progressed from rapid prototype to operational system. ISTAR has been used to support five IUS missions and countless mission simulations. There were a significant number of lessons learned with respect to integrating an expert system capability into an existing ground system.

System review: a method for investigating medical errors in healthcare settings.

PubMed

Alexander, G L; Stone, T T

2000-01-01

System analysis is a process of evaluating objectives, resources, structure, and design of businesses. System analysis can be used by leaders to collaboratively identify breakthrough opportunities to improve system processes. In healthcare systems, system analysis can be used to review medical errors (system occurrences) that may place patients at risk for injury, disability, and/or death. This study utilizes a case management approach to identify medical errors. Utilizing an interdisciplinary approach, a System Review Team was developed to identify trends in system occurrences, facilitate communication, and enhance the quality of patient care by reducing medical errors.

Transportation Systems Evaluation

NASA Technical Reports Server (NTRS)

Fanning, M. L.; Michelson, R. A.

1972-01-01

A methodology for the analysis of transportation systems consisting of five major interacting elements is reported. The analysis begins with the causes of travel demand: geographic, economic, and demographic characteristics as well as attitudes toward travel. Through the analysis, the interaction of these factors with the physical and economic characteristics of the transportation system is determined. The result is an evaluation of the system from the point of view of both passenger and operator. The methodology is applicable to the intraurban transit systems as well as major airlines. Applications of the technique to analysis of a PRT system and a study of intraurban air travel are given. In the discussion several unique models or techniques are mentioned: i.e., passenger preference modeling, an integrated intraurban transit model, and a series of models to perform airline analysis.

Modeling and analysis of power processing systems: Feasibility investigation and formulation of a methodology

NASA Technical Reports Server (NTRS)

Biess, J. J.; Yu, Y.; Middlebrook, R. D.; Schoenfeld, A. D.

1974-01-01

A review is given of future power processing systems planned for the next 20 years, and the state-of-the-art of power processing design modeling and analysis techniques used to optimize power processing systems. A methodology of modeling and analysis of power processing equipment and systems has been formulated to fulfill future tradeoff studies and optimization requirements. Computer techniques were applied to simulate power processor performance and to optimize the design of power processing equipment. A program plan to systematically develop and apply the tools for power processing systems modeling and analysis is presented so that meaningful results can be obtained each year to aid the power processing system engineer and power processing equipment circuit designers in their conceptual and detail design and analysis tasks.

Inertial Upper Stage (IUS) software analysis

NASA Technical Reports Server (NTRS)

Grayson, W. L.; Nickel, C. E.; Rose, P. L.; Singh, R. P.

1979-01-01

The Inertial Upper Stage (IUS) System, an extension of the Space Transportation System (STS) operating regime to include higher orbits, orbital plane changes, geosynchronous orbits, and interplanetary trajectories is presented. The IUS software design, the IUS software interfaces with other systems, and the cost effectiveness in software verification are described. Tasks of the IUS discussed include: (1) design analysis; (2) validation requirements analysis; (3) interface analysis; and (4) requirements analysis.

Aerodynamic preliminary analysis system 2. Part 1: Theory

NASA Technical Reports Server (NTRS)

Bonner, E.; Clever, W.; Dunn, K.

1981-01-01

A subsonic/supersonic/hypersonic aerodynamic analysis was developed by integrating the Aerodynamic Preliminary Analysis System (APAS), and the inviscid force calculation modules of the Hypersonic Arbitrary Body Program. APAS analysis was extended for nonlinear vortex forces using a generalization of the Polhamus analogy. The interactive system provides appropriate aerodynamic models for a single input geometry data base and has a run/output format similar to a wind tunnel test program. The user's manual was organized to cover the principle system activities of a typical application, geometric input/editing, aerodynamic evaluation, and post analysis review/display. Sample sessions are included to illustrate the specific task involved and are followed by a comprehensive command/subcommand dictionary used to operate the system.

Postflight Analysis of the Apollo 14 Cryogenic Oxygen System

NASA Technical Reports Server (NTRS)

Rule, D. D.

1972-01-01

A postflight analysis of the Apollo 14 cryogenic oxygen system is presented. The subjects discussed are: (1) methods of analysis, (2) stratification and heat transfer, (3) flight analysis, (4) postflight analysis, and (5) determination of model parameters.

Using Solid State Disk Array as a Cache for LHC ATLAS Data Analysis

NASA Astrophysics Data System (ADS)

Yang, W.; Hanushevsky, A. B.; Mount, R. P.; Atlas Collaboration

2014-06-01

User data analysis in high energy physics presents a challenge to spinning-disk based storage systems. The analysis is data intense, yet reads are small, sparse and cover a large volume of data files. It is also unpredictable due to users' response to storage performance. We describe here a system with an array of Solid State Disk as a non-conventional, standalone file level cache in front of the spinning disk storage to help improve the performance of LHC ATLAS user analysis at SLAC. The system uses several days of data access records to make caching decisions. It can also use information from other sources such as a work-flow management system. We evaluate the performance of the system both in terms of caching and its impact on user analysis jobs. The system currently uses Xrootd technology, but the technique can be applied to any storage system.

System safety education focused on system management

NASA Technical Reports Server (NTRS)

Grose, V. L.

1971-01-01

System safety is defined and characteristics of the system are outlined. Some of the principle characteristics include role of humans in hazard analysis, clear language for input and output, system interdependence, self containment, and parallel analysis of elements.

Analysis of chaos in high-dimensional wind power system.

PubMed

Wang, Cong; Zhang, Hongli; Fan, Wenhui; Ma, Ping

2018-01-01

A comprehensive analysis on the chaos of a high-dimensional wind power system is performed in this study. A high-dimensional wind power system is more complex than most power systems. An 11-dimensional wind power system proposed by Huang, which has not been analyzed in previous studies, is investigated. When the systems are affected by external disturbances including single parameter and periodic disturbance, or its parameters changed, chaotic dynamics of the wind power system is analyzed and chaotic parameters ranges are obtained. Chaos existence is confirmed by calculation and analysis of all state variables' Lyapunov exponents and the state variable sequence diagram. Theoretical analysis and numerical simulations show that the wind power system chaos will occur when parameter variations and external disturbances change to a certain degree.

Analysis and design of a capsule landing system and surface vehicle control system for Mars exploration

NASA Technical Reports Server (NTRS)

Frederick, D. K.; Lashmet, P. K.; Sandor, G. N.; Shen, C. N.; Smith, E. V.; Yerazunis, S. W.

1973-01-01

Problems related to the design and control of a mobile planetary vehicle to implement a systematic plan for the exploration of Mars are reported. Problem areas include: vehicle configuration, control, dynamics, systems and propulsion; systems analysis, terrain modeling and path selection; and chemical analysis of specimens. These tasks are summarized: vehicle model design, mathematical model of vehicle dynamics, experimental vehicle dynamics, obstacle negotiation, electrochemical controls, remote control, collapsibility and deployment, construction of a wheel tester, wheel analysis, payload design, system design optimization, effect of design assumptions, accessory optimal design, on-board computer subsystem, laser range measurement, discrete obstacle detection, obstacle detection systems, terrain modeling, path selection system simulation and evaluation, gas chromatograph/mass spectrometer system concepts, and chromatograph model evaluation and improvement.

Cost-Benefit Analysis of the Officer Career Information and Planning System

DTIC Science & Technology

1980-08-01

information without the use of a computer. - vii COST-BENEFIT ANALYSIS OF THE OFFICER CAREER INFOýKATTON AND PLANNING SYSTEM CONTENTS Page INTRODUCTION ...OF THE OFFICER CAREER INFORMATION AND PLANNING SYSTEM INTRODUCTION The implementation of the Officer Personnel Management System (OPMS) has...Research Report 1256 I / COST-BENEFIT ANALYSIS OF THE OFFICER CAREER INFORMATION AND PLANNING SYSTEM Roger A. Myers, Peter C. Cairo, K - Jon A

GIS-Based crash referencing and analysis system

DOT National Transportation Integrated Search

1999-02-01

One area where a Geographic Information System (GIS) has yet to be extensively applied is in the analysis of crash data. Computerized crash analysis systems in which crash data, roadway inventory data, and traffic operations data can be merged are us...

78 FR 38096 - Fatality Analysis Reporting System Information Collection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-25

... Number NHTSA-2012-0168] Fatality Analysis Reporting System Information Collection AGENCY: National... comments on the following proposed collections of information: (1) Title: Fatal Analysis Reporting System... comment on proposed collection of information. SUMMARY: Before a Federal agency can collect certain...

Estimating optical imaging system performance for space applications

NASA Technical Reports Server (NTRS)

Sinclair, K. F.

1972-01-01

The critical system elements of an optical imaging system are identified and a method for an initial assessment of system performance is presented. A generalized imaging system is defined. A system analysis is considered, followed by a component analysis. An example of the method is given using a film imaging system.

The Role of System Analysis in Education Management: A Pragmatic Appraisal and a New Perspective.

ERIC Educational Resources Information Center

Evans, John A.

This paper explores the potential of systems analysis for the educational manager. It contains a review of systems concepts with comments on current and proper practice. An application model of systems analysis in an organizational context is provided to foster rational decisionmaking and increased skill in problem finding and solving. The…

Space shuttle navigation analysis. Volume 2: Baseline system navigation

NASA Technical Reports Server (NTRS)

Jones, H. L.; Luders, G.; Matchett, G. A.; Rains, R. G.

1980-01-01

Studies related to the baseline navigation system for the orbiter are presented. The baseline navigation system studies include a covariance analysis of the Inertial Measurement Unit calibration and alignment procedures, postflight IMU error recovery for the approach and landing phases, on-orbit calibration of IMU instrument biases, and a covariance analysis of entry and prelaunch navigation system performance.

Linear circuit analysis program for IBM 1620 Monitor 2, 1311/1443 data processing system /CIRCS/

NASA Technical Reports Server (NTRS)

Hatfield, J.

1967-01-01

CIRCS is modification of IBSNAP Circuit Analysis Program, for use on smaller systems. This data processing system retains the basic dc, transient analysis, and FORTRAN 2 formats. It can be used on the IBM 1620/1311 Monitor I Mod 5 system, and solves a linear network containing 15 nodes and 45 branches.

Modeling and Analysis of Mixed Synchronous/Asynchronous Systems

NASA Technical Reports Server (NTRS)

Driscoll, Kevin R.; Madl. Gabor; Hall, Brendan

2012-01-01

Practical safety-critical distributed systems must integrate safety critical and non-critical data in a common platform. Safety critical systems almost always consist of isochronous components that have synchronous or asynchronous interface with other components. Many of these systems also support a mix of synchronous and asynchronous interfaces. This report presents a study on the modeling and analysis of asynchronous, synchronous, and mixed synchronous/asynchronous systems. We build on the SAE Architecture Analysis and Design Language (AADL) to capture architectures for analysis. We present preliminary work targeted to capture mixed low- and high-criticality data, as well as real-time properties in a common Model of Computation (MoC). An abstract, but representative, test specimen system was created as the system to be modeled.

Systems design analysis applied to launch vehicle configuration

NASA Technical Reports Server (NTRS)

Ryan, R.; Verderaime, V.

1993-01-01

As emphasis shifts from optimum-performance aerospace systems to least lift-cycle costs, systems designs must seek, adapt, and innovate cost improvement techniques in design through operations. The systems design process of concept, definition, and design was assessed for the types and flow of total quality management techniques that may be applicable in a launch vehicle systems design analysis. Techniques discussed are task ordering, quality leverage, concurrent engineering, Pareto's principle, robustness, quality function deployment, criteria, and others. These cost oriented techniques are as applicable to aerospace systems design analysis as to any large commercial system.

Chandra Interactive Analysis of Observations (CIAO)

NASA Technical Reports Server (NTRS)

Dobrzycki, Adam

2000-01-01

The Chandra (formerly AXAF) telescope, launched on July 23, 1999, provides X-rays data with unprecedented spatial and spectral resolution. As part of the Chandra scientific support, the Chandra X-ray Observatory Center provides a new data analysis system, CIAO ("Chandra Interactive Analysis of Observations"). We will present the main components of the system: "First Look" analysis; SHERPA: a multi-dimensional, multi-mission modeling and fitting application; Chandra Imaging and Plotting System; Detect package-source detection algorithms; and DM package generic data manipulation tools, We will set up a demonstration of the portable version of the system and show examples of Chandra Data Analysis.

Control system design and analysis using the INteractive Controls Analysis (INCA) program

NASA Technical Reports Server (NTRS)

Bauer, Frank H.; Downing, John P.

1987-01-01

The INteractive Controls Analysis (INCA) program was developed at the Goddard Space Flight Center to provide a user friendly efficient environment for the design and analysis of linear control systems. Since its inception, INCA has found extensive use in the design, development, and analysis of control systems for spacecraft, instruments, robotics, and pointing systems. Moreover, the results of the analytic tools imbedded in INCA have been flight proven with at least three currently orbiting spacecraft. This paper describes the INCA program and illustrates, using a flight proven example, how the package can perform complex design analyses with relative ease.

Lab-on-a-chip based total-phosphorus analysis device utilizing a photocatalytic reaction

NASA Astrophysics Data System (ADS)

Jung, Dong Geon; Jung, Daewoong; Kong, Seong Ho

2018-02-01

A lab-on-a-chip (LOC) device for total phosphorus (TP) analysis was fabricated for water quality monitoring. Many commercially available TP analysis systems used to estimate water quality have good sensitivity and accuracy. However, these systems also have many disadvantages such as bulky size, complex pretreatment processes, and high cost, which limit their application. In particular, conventional TP analysis systems require an indispensable pretreatment step, in which the fluidic analyte is heated to 120 °C for 30 min to release the dissolved phosphate, because many phosphates are soluble in water at a standard temperature and pressure. In addition, this pretreatment process requires elevated pressures of up to 1.1 kg cm-2 in order to prevent the evaporation of the heated analyte. Because of these limiting conditions required by the pretreatment processes used in conventional systems, it is difficult to miniaturize TP analysis systems. In this study, we employed a photocatalytic reaction in the pretreatment process. The reaction was carried out by illuminating a photocatalytic titanium dioxide (TiO2) surface formed in a microfluidic channel with ultraviolet (UV) light. This pretreatment process does not require elevated temperatures and pressures. By applying this simplified, photocatalytic-reaction-based pretreatment process to a TP analysis system, greater degrees of freedom are conferred to the design and fabrication of LOC devices for TP monitoring. The fabricated LOC device presented in this paper was characterized by measuring the TP concentration of an unknown sample, and comparing the results with those measured by a conventional TP analysis system. The TP concentrations of the unknown sample measured by the proposed LOC device and the conventional TP analysis system were 0.018 mgP/25 mL and 0.019 mgP/25 mL, respectively. The experimental results revealed that the proposed LOC device had a performance comparable to the conventional bulky TP analysis system. Therefore, our device could be directly employed in water quality monitoring as an alternative to conventional TP analysis systems.

Data engineering systems: Computerized modeling and data bank capabilities for engineering analysis

NASA Technical Reports Server (NTRS)

Kopp, H.; Trettau, R.; Zolotar, B.

1984-01-01

The Data Engineering System (DES) is a computer-based system that organizes technical data and provides automated mechanisms for storage, retrieval, and engineering analysis. The DES combines the benefits of a structured data base system with automated links to large-scale analysis codes. While the DES provides the user with many of the capabilities of a computer-aided design (CAD) system, the systems are actually quite different in several respects. A typical CAD system emphasizes interactive graphics capabilities and organizes data in a manner that optimizes these graphics. On the other hand, the DES is a computer-aided engineering system intended for the engineer who must operationally understand an existing or planned design or who desires to carry out additional technical analysis based on a particular design. The DES emphasizes data retrieval in a form that not only provides the engineer access to search and display the data but also links the data automatically with the computer analysis codes.

MOD-0A 200 kW wind turbine generator design and analysis report

NASA Astrophysics Data System (ADS)

Anderson, T. S.; Bodenschatz, C. A.; Eggers, A. G.; Hughes, P. S.; Lampe, R. F.; Lipner, M. H.; Schornhorst, J. R.

1980-08-01

The design, analysis, and initial performance of the MOD-OA 200 kW wind turbine generator at Clayton, NM is documented. The MOD-OA was designed and built to obtain operation and performance data and experience in utility environments. The project requirements, approach, system description, design requirements, design, analysis, system tests, installation, safety considerations, failure modes and effects analysis, data acquisition, and initial performance for the wind turbine are discussed. The design and analysis of the rotor, drive train, nacelle equipment, yaw drive mechanism and brake, tower, foundation, electricl system, and control systems are presented. The rotor includes the blades, hub, and pitch change mechanism. The drive train includes the low speed shaft, speed increaser, high speed shaft, and rotor brake. The electrical system includes the generator, switchgear, transformer, and utility connection. The control systems are the blade pitch, yaw, and generator control, and the safety system. Manual, automatic, and remote control are discussed. Systems analyses on dynamic loads and fatigue are presented.

MOD-0A 200 kW wind turbine generator design and analysis report

NASA Technical Reports Server (NTRS)

Anderson, T. S.; Bodenschatz, C. A.; Eggers, A. G.; Hughes, P. S.; Lampe, R. F.; Lipner, M. H.; Schornhorst, J. R.

1980-01-01

The design, analysis, and initial performance of the MOD-OA 200 kW wind turbine generator at Clayton, NM is documented. The MOD-OA was designed and built to obtain operation and performance data and experience in utility environments. The project requirements, approach, system description, design requirements, design, analysis, system tests, installation, safety considerations, failure modes and effects analysis, data acquisition, and initial performance for the wind turbine are discussed. The design and analysis of the rotor, drive train, nacelle equipment, yaw drive mechanism and brake, tower, foundation, electricl system, and control systems are presented. The rotor includes the blades, hub, and pitch change mechanism. The drive train includes the low speed shaft, speed increaser, high speed shaft, and rotor brake. The electrical system includes the generator, switchgear, transformer, and utility connection. The control systems are the blade pitch, yaw, and generator control, and the safety system. Manual, automatic, and remote control are discussed. Systems analyses on dynamic loads and fatigue are presented.

Lessons Learned from Application of System and Software Level RAMS Analysis to a Space Control System

NASA Astrophysics Data System (ADS)

Silva, N.; Esper, A.

2012-01-01

The work presented in this article represents the results of applying RAMS analysis to a critical space control system, both at system and software levels. The system level RAMS analysis allowed the assignment of criticalities to the high level components, which was further refined by a tailored software level RAMS analysis. The importance of the software level RAMS analysis in the identification of new failure modes and its impact on the system level RAMS analysis is discussed. Recommendations of changes in the software architecture have also been proposed in order to reduce the criticality of the SW components to an acceptable minimum. The dependability analysis was performed in accordance to ECSS-Q-ST-80, which had to be tailored and complemented in some aspects. This tailoring will also be detailed in the article and lessons learned from the application of this tailoring will be shared, stating the importance to space systems safety evaluations. The paper presents the applied techniques, the relevant results obtained, the effort required for performing the tasks and the planned strategy for ROI estimation, as well as the soft skills required and acquired during these activities.

How Can Visual Analytics Assist Investigative Analysis? Design Implications from an Evaluation.

PubMed

Youn-Ah Kang; Görg, Carsten; Stasko, John

2011-05-01

Despite the growing number of systems providing visual analytic support for investigative analysis, few empirical studies of the potential benefits of such systems have been conducted, particularly controlled, comparative evaluations. Determining how such systems foster insight and sensemaking is important for their continued growth and study, however. Furthermore, studies that identify how people use such systems and why they benefit (or not) can help inform the design of new systems in this area. We conducted an evaluation of the visual analytics system Jigsaw employed in a small investigative sensemaking exercise, and compared its use to three other more traditional methods of analysis. Sixteen participants performed a simulated intelligence analysis task under one of the four conditions. Experimental results suggest that Jigsaw assisted participants to analyze the data and identify an embedded threat. We describe different analysis strategies used by study participants and how computational support (or the lack thereof) influenced the strategies. We then illustrate several characteristics of the sensemaking process identified in the study and provide design implications for investigative analysis tools based thereon. We conclude with recommendations on metrics and techniques for evaluating visual analytics systems for investigative analysis.

Heating Analysis in Constant-pressure Hydraulic System based on Energy Analysis

NASA Astrophysics Data System (ADS)

Wu, Chao; Xu, Cong; Mao, Xuyao; Li, Bin; Hu, Junhua; Liu, Yiou

2017-12-01

Hydraulic systems are widely used in industrial applications, but the problem of heating has become an important reason to restrict the promotion of hydraulic technology. The high temperature, will seriously affect the operation of the hydraulic system, even cause stuck and other serious failure. Based on the analysis of the heat damage of the hydraulic system, this paper gives the reasons for this problem, and it is showed by the application that the energy analysis can accurately locate the main reasons for the heating of the hydraulic system, which can give strong practical guidance.

Comparison of existing digital image analysis systems for the analysis of Thematic Mapper data

NASA Technical Reports Server (NTRS)

Likens, W. C.; Wrigley, R. C.

1984-01-01

Most existing image analysis systems were designed with the Landsat Multi-Spectral Scanner in mind, leaving open the question of whether or not these systems could adequately process Thematic Mapper data. In this report, both hardware and software systems have been evaluated for compatibility with TM data. Lack of spectral analysis capability was not found to be a problem, though techniques for spatial filtering and texture varied. Computer processing speed and data storage of currently existing mini-computer based systems may be less than adequate. Upgrading to more powerful hardware may be required for many TM applications.

Rocketdyne automated dynamics data analysis and management system

NASA Technical Reports Server (NTRS)

Tarn, Robert B.

1988-01-01

An automated dynamics data analysis and management systems implemented on a DEC VAX minicomputer cluster is described. Multichannel acquisition, Fast Fourier Transformation analysis, and an online database have significantly improved the analysis of wideband transducer responses from Space Shuttle Main Engine testing. Leakage error correction to recover sinusoid amplitudes and correct for frequency slewing is described. The phase errors caused by FM recorder/playback head misalignment are automatically measured and used to correct the data. Data compression methods are described and compared. The system hardware is described. Applications using the data base are introduced, including software for power spectral density, instantaneous time history, amplitude histogram, fatigue analysis, and rotordynamics expert system analysis.

[Design of high-efficiency double compound parabolic concentrator system in near infrared noninvasive biochemical analysis].

PubMed

Gao, Jing; Lu, Qi-Peng; Peng, Zhong-Qi; Ding, Hai-Quan; Gao, Hong-Zhi

2013-05-01

High signal-to-noise ratio (SNR) of system is necessary to obtain accurate blood components in near infrared noninvasive biochemical analysis. In order to improve SNR of analytical system, high-efficiency double compound parabolic concentrator (DCPC) system was researched, which was aimed at increasing light utilization efficiency. Firstly, with the request of collection efficiency in near infrared noninvasive biochemical analysis, the characteristic of emergent rays through compound parabolic concentrator (CPC) was analyzed. Then the maximum focusing angle range of the first stage CPC was determined. Secondly, the light utilization efficiency of truncated type was compared with standard DCPC, thus the best structure parameters of DCPC system were optimized. Lastly, combined with optical parameters of skin tissue, calculations were operated when incident wavelength is 1 000 nm. The light utilization efficiency of DCPC system, CPC-focusing mirror system, and non-optical collecting system was calculated. The results show that the light utilization efficiency of the three optical systems is 1.46%, 0.84% and 0.26% respectively. So DCPC system enhances collecting ability for human diffuse reflection light, and helps improve SNR of noninvasive biochemical analysis system and overall analysis accuracy effectively.

Overview of the land analysis system (LAS)

USGS Publications Warehouse

Quirk, Bruce K.; Olseson, Lyndon R.

1987-01-01

The Land Analysis System (LAS) is a fully integrated digital analysis system designed to support remote sensing, image processing, and geographic information systems research. LAS is being developed through a cooperative effort between the National Aeronautics and Space Administration Goddard Space Flight Center and the U. S. Geological Survey Earth Resources Observation Systems (EROS) Data Center. LAS has over 275 analysis modules capable to performing input and output, radiometric correction, geometric registration, signal processing, logical operations, data transformation, classification, spatial analysis, nominal filtering, conversion between raster and vector data types, and display manipulation of image and ancillary data. LAS is currently implant using the Transportable Applications Executive (TAE). While TAE was designed primarily to be transportable, it still provides the necessary components for a standard user interface, terminal handling, input and output services, display management, and intersystem communications. With TAE the analyst uses the same interface to the processing modules regardless of the host computer or operating system. LAS was originally implemented at EROS on a Digital Equipment Corporation computer system under the Virtual Memorial System operating system with DeAnza displays and is presently being converted to run on a Gould Power Node and Sun workstation under the Berkeley System Distribution UNIX operating system.

21 CFR 864.7440 - Electrophoretic hemoglobin analysis system.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Electrophoretic hemoglobin analysis system. 864.7440 Section 864.7440 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN....7440 Electrophoretic hemoglobin analysis system. (a) Identification. An electrophoretic hemoglobin...

21 CFR 864.7440 - Electrophoretic hemoglobin analysis system.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Electrophoretic hemoglobin analysis system. 864.7440 Section 864.7440 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN....7440 Electrophoretic hemoglobin analysis system. (a) Identification. An electrophoretic hemoglobin...

21 CFR 864.7440 - Electrophoretic hemoglobin analysis system.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Electrophoretic hemoglobin analysis system. 864.7440 Section 864.7440 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN....7440 Electrophoretic hemoglobin analysis system. (a) Identification. An electrophoretic hemoglobin...

21 CFR 864.7440 - Electrophoretic hemoglobin analysis system.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Electrophoretic hemoglobin analysis system. 864.7440 Section 864.7440 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN....7440 Electrophoretic hemoglobin analysis system. (a) Identification. An electrophoretic hemoglobin...

21 CFR 864.7440 - Electrophoretic hemoglobin analysis system.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Electrophoretic hemoglobin analysis system. 864.7440 Section 864.7440 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN....7440 Electrophoretic hemoglobin analysis system. (a) Identification. An electrophoretic hemoglobin...

Miniaturized flow injection analysis system

DOEpatents

Folta, James A.

1997-01-01

A chemical analysis technique known as flow injection analysis, wherein small quantities of chemical reagents and sample are intermixed and reacted within a capillary flow system and the reaction products are detected optically, electrochemically, or by other means. A highly miniaturized version of a flow injection analysis system has been fabricated utilizing microfabrication techniques common to the microelectronics industry. The microflow system uses flow capillaries formed by etching microchannels in a silicon or glass wafer followed by bonding to another wafer, commercially available microvalves bonded directly to the microflow channels, and an optical absorption detector cell formed near the capillary outlet, with light being both delivered and collected with fiber optics. The microflow system is designed mainly for analysis of liquids and currently measures 38.times.25.times.3 mm, but can be designed for gas analysis and be substantially smaller in construction.

The IDEAL (Integrated Design and Engineering Analysis Languages) modeling methodology: Capabilities and Applications

NASA Technical Reports Server (NTRS)

Evers, Ken H.; Bachert, Robert F.

1987-01-01

The IDEAL (Integrated Design and Engineering Analysis Languages) modeling methodology has been formulated and applied over a five-year period. It has proven to be a unique, integrated approach utilizing a top-down, structured technique to define and document the system of interest; a knowledge engineering technique to collect and organize system descriptive information; a rapid prototyping technique to perform preliminary system performance analysis; and a sophisticated simulation technique to perform in-depth system performance analysis.

Computer-aided-engineering system for modeling and analysis of ECLSS integration testing

NASA Technical Reports Server (NTRS)

Sepahban, Sonbol

1987-01-01

The accurate modeling and analysis of two-phase fluid networks found in environmental control and life support systems is presently undertaken by computer-aided engineering (CAE) techniques whose generalized fluid dynamics package can solve arbitrary flow networks. The CAE system for integrated test bed modeling and analysis will also furnish interfaces and subsystem/test-article mathematical models. Three-dimensional diagrams of the test bed are generated by the system after performing the requisite simulation and analysis.

STS-1 environmental control and life support system. Consumables and thermal analysis

NASA Technical Reports Server (NTRS)

Steines, G.

1980-01-01

The Environmental Control and Life Support Systems (ECLSS)/thermal systems analysis for the Space Transportation System 1 Flight (STS-1) was performed using the shuttle environmental consumables usage requirements evaluation (SECURE) computer program. This program employs a nodal technique utilizing the Fortran Environmental Analysis Routines (FEAR). The output parameters evaluated were consumable quantities, fluid temperatures, heat transfer and rejection, and cabin atmospheric pressure. Analysis of these indicated that adequate margins exist for the nonpropulsive consumables and related thermal environment.

FASEA: A FPGA Acquisition System and Software Event Analysis for liquid scintillation counting

NASA Astrophysics Data System (ADS)

Steele, T.; Mo, L.; Bignell, L.; Smith, M.; Alexiev, D.

2009-10-01

The FASEA (FPGA based Acquisition and Software Event Analysis) system has been developed to replace the MAC3 for coincidence pulse processing. The system uses a National Instruments Virtex 5 FPGA card (PXI-7842R) for data acquisition and a purpose developed data analysis software for data analysis. Initial comparisons to the MAC3 unit are included based on measurements of 89Sr and 3H, confirming that the system is able to accurately emulate the behaviour of the MAC3 unit.

How a submarine returns to periscope depth: analysing complex socio-technical systems using Cognitive Work Analysis.

PubMed

Stanton, Neville A; Bessell, Kevin

2014-01-01

This paper presents the application of Cognitive Work Analysis to the description of the functions, situations, activities, decisions, strategies, and competencies of a Trafalgar class submarine when performing the function of returning to periscope depth. All five phases of Cognitive Work Analysis are presented, namely: Work Domain Analysis, Control Task Analysis, Strategies Analysis, Social Organisation and Cooperation Analysis, and Worker Competencies Analysis. Complex socio-technical systems are difficult to analyse but Cognitive Work Analysis offers an integrated way of analysing complex systems with the core of functional means-ends analysis underlying all of the other representations. The joined-up analysis offers a coherent framework for understanding how socio-technical systems work. Data were collected through observation and interviews at different sites across the UK. The resultant representations present a statement of how the work domain and current activities are configured in this complex socio-technical system. This is intended to provide a baseline, from which all future conceptions of the domain may be compared. The strength of the analysis is in the multiple representations from which the constraints acting on the work may be analysed. Future research needs to challenge the assumptions behind these constraints in order to develop new ways of working. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

LOFT L2-3 blowdown experiment safety analyses D, E, and G; LOCA analyses H, K, K1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perryman, J.L.; Keeler, C.D.; Saukkoriipi, L.O.

1978-12-01

Three calculations using conservative off-nominal conditions and evaluation model options were made using RELAP4/MOD5 for blowdown-refill and RELAP4/MOD6 for reflood for Loss-of-Fluid Test Experiment L2-3 to support the experiment safety analysis effort. The three analyses are as follows: Analysis D: Loss of commercial power during Experiment L2-3; Analysis E: Hot leg quick-opening blowdown valve (QOBV) does not open during Experiment L2-3; and Analysis G: Cold leg QOBV does not open during Experiment L2-3. In addition, the results of three LOFT loss-of-coolant accident (LOCA) analyses using a power of 56.1 MW and a primary coolant system flow rate of 3.6 millionmore » 1bm/hr are presented: Analysis H: Intact loop 200% hot leg break; emergency core cooling (ECC) system B unavailable; Analysis K: Pressurizer relief valve stuck in open position; ECC system B unavailable; and Analysis K1: Same as analysis K, but using a primary coolant system flow rate of 1.92 million 1bm/hr (L2-4 pre-LOCE flow rate). For analysis D, the maximum cladding temperature reached was 1762/sup 0/F, 22 sec into reflood. In analyses E and G, the blowdowns were slower due to one of the QOBVs not functioning. The maximum cladding temperature reached in analysis E was 1700/sup 0/F, 64.7 sec into reflood; for analysis G, it was 1300/sup 0/F at the start of reflood. For analysis H, the maximum cladding temperature reached was 1825/sup 0/F, 0.01 sec into reflood. Analysis K was a very slow blowdown, and the cladding temperatures followed the saturation temperature of the system. The results of analysis K1 was nearly identical to analysis K; system depressurization was not affected by the primary coolant system flow rate.« less

An Advanced Platform for Biomolecular Detection and Analysis Systems

DTIC Science & Technology

2005-02-01

AFRL-IF-RS-TR-2005-54 Final Technical Report February 2005 AN ADVANCED PLATFORM FOR BIOMOLECULAR DETECTION AND ANALYSIS SYSTEMS...SUBTITLE AN ADVANCED PLATFORM FOR BIOMOLECULAR DETECTION AND ANALYSIS SYSTEMS 6. AUTHOR(S) David J. Beebe 5. FUNDING NUMBERS G...detection, analysis and response as well as many non BC warfare applications such as environmental toxicology, clinical detection and diagnosis

Requirements analysis notebook for the flight data systems definition in the Real-Time Systems Engineering Laboratory (RSEL)

NASA Astrophysics Data System (ADS)

Wray, Richard B.

1991-12-01

A hybrid requirements analysis methodology was developed, based on the practices actually used in developing a Space Generic Open Avionics Architecture. During the development of this avionics architecture, a method of analysis able to effectively define the requirements for this space avionics architecture was developed. In this methodology, external interfaces and relationships are defined, a static analysis resulting in a static avionics model was developed, operating concepts for simulating the requirements were put together, and a dynamic analysis of the execution needs for the dynamic model operation was planned. The systems engineering approach was used to perform a top down modified structured analysis of a generic space avionics system and to convert actual program results into generic requirements. CASE tools were used to model the analyzed system and automatically generate specifications describing the model's requirements. Lessons learned in the use of CASE tools, the architecture, and the design of the Space Generic Avionics model were established, and a methodology notebook was prepared for NASA. The weaknesses of standard real-time methodologies for practicing systems engineering, such as Structured Analysis and Object Oriented Analysis, were identified.

Requirements analysis notebook for the flight data systems definition in the Real-Time Systems Engineering Laboratory (RSEL)

NASA Technical Reports Server (NTRS)

Wray, Richard B.

1991-01-01

A hybrid requirements analysis methodology was developed, based on the practices actually used in developing a Space Generic Open Avionics Architecture. During the development of this avionics architecture, a method of analysis able to effectively define the requirements for this space avionics architecture was developed. In this methodology, external interfaces and relationships are defined, a static analysis resulting in a static avionics model was developed, operating concepts for simulating the requirements were put together, and a dynamic analysis of the execution needs for the dynamic model operation was planned. The systems engineering approach was used to perform a top down modified structured analysis of a generic space avionics system and to convert actual program results into generic requirements. CASE tools were used to model the analyzed system and automatically generate specifications describing the model's requirements. Lessons learned in the use of CASE tools, the architecture, and the design of the Space Generic Avionics model were established, and a methodology notebook was prepared for NASA. The weaknesses of standard real-time methodologies for practicing systems engineering, such as Structured Analysis and Object Oriented Analysis, were identified.

State Analysis Database Tool

NASA Technical Reports Server (NTRS)

Rasmussen, Robert; Bennett, Matthew

2006-01-01

The State Analysis Database Tool software establishes a productive environment for collaboration among software and system engineers engaged in the development of complex interacting systems. The tool embodies State Analysis, a model-based system engineering methodology founded on a state-based control architecture (see figure). A state represents a momentary condition of an evolving system, and a model may describe how a state evolves and is affected by other states. The State Analysis methodology is a process for capturing system and software requirements in the form of explicit models and states, and defining goal-based operational plans consistent with the models. Requirements, models, and operational concerns have traditionally been documented in a variety of system engineering artifacts that address different aspects of a mission s lifecycle. In State Analysis, requirements, models, and operations information are State Analysis artifacts that are consistent and stored in a State Analysis Database. The tool includes a back-end database, a multi-platform front-end client, and Web-based administrative functions. The tool is structured to prompt an engineer to follow the State Analysis methodology, to encourage state discovery and model description, and to make software requirements and operations plans consistent with model descriptions.

Complex systems and the technology of variability analysis

PubMed Central

Seely, Andrew JE; Macklem, Peter T

2004-01-01

Characteristic patterns of variation over time, namely rhythms, represent a defining feature of complex systems, one that is synonymous with life. Despite the intrinsic dynamic, interdependent and nonlinear relationships of their parts, complex biological systems exhibit robust systemic stability. Applied to critical care, it is the systemic properties of the host response to a physiological insult that manifest as health or illness and determine outcome in our patients. Variability analysis provides a novel technology with which to evaluate the overall properties of a complex system. This review highlights the means by which we scientifically measure variation, including analyses of overall variation (time domain analysis, frequency distribution, spectral power), frequency contribution (spectral analysis), scale invariant (fractal) behaviour (detrended fluctuation and power law analysis) and regularity (approximate and multiscale entropy). Each technique is presented with a definition, interpretation, clinical application, advantages, limitations and summary of its calculation. The ubiquitous association between altered variability and illness is highlighted, followed by an analysis of how variability analysis may significantly improve prognostication of severity of illness and guide therapeutic intervention in critically ill patients. PMID:15566580

Parallel Hybrid Gas-Electric Geared Turbofan Engine Conceptual Design and Benefits Analysis

NASA Technical Reports Server (NTRS)

Lents, Charles; Hardin, Larry; Rheaume, Jonathan; Kohlman, Lee

2016-01-01

The conceptual design of a parallel gas-electric hybrid propulsion system for a conventional single aisle twin engine tube and wing vehicle has been developed. The study baseline vehicle and engine technology are discussed, followed by results of the hybrid propulsion system sizing and performance analysis. The weights analysis for the electric energy storage & conversion system and thermal management system is described. Finally, the potential system benefits are assessed.

A Merged IQC/SOS Theory for Analysis and Synthesis of Nonlinear Control Systems

DTIC Science & Technology

2015-06-23

constraints. As mentioned previously, this enables new applications of IQCs to analyze the robustness of time-varying and nonlinear systems . This...enables new applications of IQCs to analyze the robustness of time-varying and nonlinear systems . This section considers the analysis of nonlinear systems ...AFRL-AFOSR-VA-TR-2016-0008 A Merged IQC/SOS Theory for Analysis and Synthesis of Nonlinear Control Systems Gary Balas REGENTS OF THE UNIVERSITY OF

Market Assessment of Forward-Looking Turbulence Sensing Systems

NASA Technical Reports Server (NTRS)

Kauffmann, Paul

2003-01-01

This viewgraph presentation provides a cost benefit analysis of three next-generation forward-looking turbulence sensing systems: X band turbulence radar system for convective turbulence, LIDAR based turbulence systems to sense clear air turbulence and a combined hybrid system. Parameters for the cost benefit analysis were established using a business model which considered injury rates, cost of injuries, indirect costs, market penetration rate estimates and product success characteristics. Topics covered include: study approach, business case equations, data acquisition, benchmark analysis. Data interpretation from the cost benefit analysis is presented. The researchers conclude that the market potential for these products is based primarily on injury cost reduction and that X band radar systems have the greatest chance for commercial success.

Guide to the economic analysis of community energy systems

NASA Astrophysics Data System (ADS)

Pferdehirt, W. P.; Croke, K. G.; Hurter, A. P.; Kennedy, A. S.; Lee, C.

1981-08-01

This guidebook provides a framework for the economic analysis of community energy systems. The analysis facilitates a comparison of competing configurations in community energy systems, as well as a comparison with conventional energy systems. Various components of costs and revenues to be considered are discussed in detail. Computational procedures and accompanying worksheets are provided for calculating the net present value, straight and discounted payback periods, the rate of return, and the savings to investment ratio for the proposed energy system alternatives. These computations are based on a projection of the system's costs and revenues over its economic lifetimes. The guidebook also discusses the sensitivity of the results of this economic analysis to changes in various parameters and assumptions.

Convergence Estimates for Multidisciplinary Analysis and Optimization

NASA Technical Reports Server (NTRS)

Arian, Eyal

1997-01-01

A quantitative analysis of coupling between systems of equations is introduced. This analysis is then applied to problems in multidisciplinary analysis, sensitivity, and optimization. For the sensitivity and optimization problems both multidisciplinary and single discipline feasibility schemes are considered. In all these cases a "convergence factor" is estimated in terms of the Jacobians and Hessians of the system, thus it can also be approximated by existing disciplinary analysis and optimization codes. The convergence factor is identified with the measure for the "coupling" between the disciplines in the system. Applications to algorithm development are discussed. Demonstration of the convergence estimates and numerical results are given for a system composed of two non-linear algebraic equations, and for a system composed of two PDEs modeling aeroelasticity.

Modeling Tools for Propulsion Analysis and Computational Fluid Dynamics on the Internet

NASA Technical Reports Server (NTRS)

Muss, J. A.; Johnson, C. W.; Gotchy, M. B.

2000-01-01

The existing RocketWeb(TradeMark) Internet Analysis System (httr)://www.iohnsonrockets.com/rocketweb) provides an integrated set of advanced analysis tools that can be securely accessed over the Internet. Since these tools consist of both batch and interactive analysis codes, the system includes convenient methods for creating input files and evaluating the resulting data. The RocketWeb(TradeMark) system also contains many features that permit data sharing which, when further developed, will facilitate real-time, geographically diverse, collaborative engineering within a designated work group. Adding work group management functionality while simultaneously extending and integrating the system's set of design and analysis tools will create a system providing rigorous, controlled design development, reducing design cycle time and cost.

Wavelet analysis enables system-independent texture analysis of optical coherence tomography images.

PubMed

Lingley-Papadopoulos, Colleen A; Loew, Murray H; Zara, Jason M

2009-01-01

Texture analysis for tissue characterization is a current area of optical coherence tomography (OCT) research. We discuss some of the differences between OCT systems and the effects those differences have on the resulting images and subsequent image analysis. In addition, as an example, two algorithms for the automatic recognition of bladder cancer are compared: one that was developed on a single system with no consideration for system differences, and one that was developed to address the issues associated with system differences. The first algorithm had a sensitivity of 73% and specificity of 69% when tested using leave-one-out cross-validation on data taken from a single system. When tested on images from another system with a different central wavelength, however, the method classified all images as cancerous regardless of the true pathology. By contrast, with the use of wavelet analysis and the removal of system-dependent features, the second algorithm reported sensitivity and specificity values of 87 and 58%, respectively, when trained on images taken with one imaging system and tested on images taken with another.

Probabilistic stability analysis: the way forward for stability analysis of sustainable power systems.

PubMed

Milanović, Jovica V

2017-08-13

Future power systems will be significantly different compared with their present states. They will be characterized by an unprecedented mix of a wide range of electricity generation and transmission technologies, as well as responsive and highly flexible demand and storage devices with significant temporal and spatial uncertainty. The importance of probabilistic approaches towards power system stability analysis, as a subsection of power system studies routinely carried out by power system operators, has been highlighted in previous research. However, it may not be feasible (or even possible) to accurately model all of the uncertainties that exist within a power system. This paper describes for the first time an integral approach to probabilistic stability analysis of power systems, including small and large angular stability and frequency stability. It provides guidance for handling uncertainties in power system stability studies and some illustrative examples of the most recent results of probabilistic stability analysis of uncertain power systems.This article is part of the themed issue 'Energy management: flexibility, risk and optimization'. © 2017 The Author(s).

Wavelet analysis enables system-independent texture analysis of optical coherence tomography images

NASA Astrophysics Data System (ADS)

Lingley-Papadopoulos, Colleen A.; Loew, Murray H.; Zara, Jason M.

2009-07-01

Texture analysis for tissue characterization is a current area of optical coherence tomography (OCT) research. We discuss some of the differences between OCT systems and the effects those differences have on the resulting images and subsequent image analysis. In addition, as an example, two algorithms for the automatic recognition of bladder cancer are compared: one that was developed on a single system with no consideration for system differences, and one that was developed to address the issues associated with system differences. The first algorithm had a sensitivity of 73% and specificity of 69% when tested using leave-one-out cross-validation on data taken from a single system. When tested on images from another system with a different central wavelength, however, the method classified all images as cancerous regardless of the true pathology. By contrast, with the use of wavelet analysis and the removal of system-dependent features, the second algorithm reported sensitivity and specificity values of 87 and 58%, respectively, when trained on images taken with one imaging system and tested on images taken with another.

AN ANALYSIS OF SYSTEMS FOR FEEDING HOT MEALS TO THE ARMY IN THE FIELD DURING 1975-1990 TIME FRAME.

DTIC Science & Technology

An analysis was conducted of a large number of potential systems for feeding hot meals to the Army in the field during the 1975-1990 time frame...system of company level feeding . An analysis of alternative mixed systems (company level and higher) is also made indicating greater potential for food

Finite wordlength implementation of a megachannel digital spectrum analyzer

NASA Technical Reports Server (NTRS)

Satorius, E. H.; Grimm, M. J.; Zimmerman, G. A.; Wilck, H. C.

1986-01-01

The results of an extensive system analysis of the megachannel spectrum analyzer currently being developed for use in various applications of the Deep Space Network are presented. The intent of this analysis is to quantify the effects of digital quantization errors on system performance. The results of this analysis provide useful guidelines for choosing various system design parameters to enhance system performance.

Reliability Validation and Improvement Framework

DTIC Science & Technology

2012-11-01

systems . Steps in that direction include the use of the Architec- ture Tradeoff Analysis Method ® (ATAM®) developed at the Carnegie Mellon...embedded software • cyber - physical systems (CPSs) to indicate that the embedded software interacts with, manag - es, and controls a physical system [Lee...the use of formal static analysis methods to increase our confidence in system operation beyond testing. However, analysis results

Self-conscious robotic system design process--from analysis to implementation.

PubMed

Chella, Antonio; Cossentino, Massimo; Seidita, Valeria

2011-01-01

Developing robotic systems endowed with self-conscious capabilities means realizing complex sub-systems needing ad-hoc software engineering techniques for their modelling, analysis and implementation. In this chapter the whole process (from analysis to implementation) to model the development of self-conscious robotic systems is presented and the new created design process, PASSIC, supporting each part of it, is fully illustrated.

Combining Cloud Networks and Course Management Systems for Enhanced Analysis in Teaching Laboratories

ERIC Educational Resources Information Center

Abrams, Neal M.

2012-01-01

A cloud network system is combined with standard computing applications and a course management system to provide a robust method for sharing data among students. This system provides a unique method to improve data analysis by easily increasing the amount of sampled data available for analysis. The data can be shared within one course as well as…

Teaching Tip: Using Activity Diagrams to Model Systems Analysis Techniques: Teaching What We Preach

ERIC Educational Resources Information Center

Lending, Diane; May, Jeffrey

2013-01-01

Activity diagrams are used in Systems Analysis and Design classes as a visual tool to model the business processes of "as-is" and "to-be" systems. This paper presents the idea of using these same activity diagrams in the classroom to model the actual processes (practices and techniques) of Systems Analysis and Design. This tip…

Systems analysis of a closed loop ECLSS using the ASPEN simulation tool. Thermodynamic efficiency analysis of ECLSS components. M.S. Thesis

NASA Technical Reports Server (NTRS)

Chatterjee, Sharmista

1993-01-01

Our first goal in this project was to perform a systems analysis of a closed loop Environmental Control Life Support System (ECLSS). This pertains to the development of a model of an existing real system from which to assess the state or performance of the existing system. Systems analysis is applied to conceptual models obtained from a system design effort. For our modelling purposes we used a simulator tool called ASPEN (Advanced System for Process Engineering). Our second goal was to evaluate the thermodynamic efficiency of the different components comprising an ECLSS. Use is made of the second law of thermodynamics to determine the amount of irreversibility of energy loss of each component. This will aid design scientists in selecting the components generating the least entropy, as our penultimate goal is to keep the entropy generation of the whole system at a minimum.

Reducing the Carbon Footprint of Commercial Refrigeration Systems Using Life Cycle Climate Performance Analysis: From System Design to Refrigerant Options

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fricke, Brian A; Abdelaziz, Omar; Vineyard, Edward Allan

In this paper, Life Cycle Climate Performance (LCCP) analysis is used to estimate lifetime direct and indirect carbon dioxide equivalent gas emissions of various refrigerant options and commercial refrigeration system designs, including the multiplex DX system with various hydrofluorocarbon (HFC) refrigerants, the HFC/R744 cascade system incorporating a medium-temperature R744 secondary loop, and the transcritical R744 booster system. The results of the LCCP analysis are presented, including the direct and indirect carbon dioxide equivalent emissions for each refrigeration system and refrigerant option. Based on the results of the LCCP analysis, recommendations are given for the selection of low GWP replacement refrigerantsmore » for use in existing commercial refrigeration systems, as well as for the selection of commercial refrigeration system designs with low carbon dioxide equivalent emissions, suitable for new installations.« less

Structural analysis and design for the development of floating photovoltaic energy generation system

NASA Astrophysics Data System (ADS)

Yoon, S. J.; Joo, H. J.; Kim, S. H.

2018-06-01

In this paper, we discussed the structural analysis and design for the development of floating photovoltaic energy generation system. Series of research conducted to develop the system from the analysis and design of the structural system to the installation of the system discussed. In the structural system supporting solar panels PFRP materials and SMC FRP materials used. A unit module structure is fabricated and then the unit module structures are connected each other to assemble whole PV energy generation complex. This system connected directly to the power grid system. In addition, extensive monitoring for the efficiency of electricity generation and the soundness of the structural system is in progress for the further system enhancement.

Time Analysis: Still an Important Accountability Tool.

ERIC Educational Resources Information Center

Fairchild, Thomas N.; Seeley, Tracey J.

1994-01-01

Reviews benefits to school counselors of conducting a time analysis. Describes time analysis system that authors have used, including case illustration of how authors used data to effect counseling program changes. System described followed process outlined by Fairchild: identifying services, devising coding system, keeping records, synthesizing…

Braking Analysis For Collision Avoidance-- Autonomous Braking System Performance Modeling And Benefits Analysis

DOT National Transportation Integrated Search

1996-05-24

THIS REPORT IS AN ANALYSIS OF THE BENEFITS OF A COLLISION AVOIDANCE SYSTEM IN REDUCING REAR-END CRASHES. THE COLLISION AVOIDANCE SYSTEM CONSIDERED IN THIS STUDY UTILIZES THE SIGNAL FROM A FORWARD LOOKING SENSOR TO ACTIVATE THE TRACTION CONTROL VALVE ...

Rate Monotonic Analysis for Real-Time Systems

DTIC Science & Technology

1991-03-01

The essential goal of the Rate Monotonic Analysis (RMA) for Real - Time Systems Project at the Software Engineering Institute is to catalyze...improvement in the practice of real time systems engineering, specifically by increasing the use of rate monotonic analysis and scheduling algorithms. In this

Transportation systems safety hazard analysis tool (SafetyHAT) user guide (version 1.0)

DOT National Transportation Integrated Search

2014-03-24

This is a user guide for the transportation system Safety Hazard Analysis Tool (SafetyHAT) Version 1.0. SafetyHAT is a software tool that facilitates System Theoretic Process Analysis (STPA.) This user guide provides instructions on how to download, ...

75 FR 35457 - Draft of the 2010 Causal Analysis/Diagnosis Decision Information System (CADDIS)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-22

... Causal Analysis/Diagnosis Decision Information System (CADDIS) AGENCY: Environmental Protection Agency... site, ``2010 release of the Causal Analysis/Diagnosis Decision Information System (CADDIS).'' The... analyses, downloadable software tools, and links to outside information sources. II. How to Submit Comments...

The Warning System in Disaster Situations: A Selective Analysis.

DTIC Science & Technology

DISASTERS, *WARNING SYSTEMS), CIVIL DEFENSE, SOCIAL PSYCHOLOGY, REACTION(PSYCHOLOGY), FACTOR ANALYSIS, CLASSIFICATION, STATISTICAL DATA, TIME ... MANAGEMENT PLANNING AND CONTROL, DAMAGE, CONTROL SYSTEMS, THREAT EVALUATION, DECISION MAKING, DATA PROCESSING, COMMUNICATION SYSTEMS, NUCLEAR EXPLOSIONS

Personalized Rapid Transit Systems : a First Analysis

DOT National Transportation Integrated Search

1971-07-01

A preliminary systems analysis of the presonalized rapid transit system concept is given. It includes presentatin of the significant advantages and disadvantages. Question of system capacity, station capacity, urban grid design, and headway requireme...

SCANS (Shipping Cask ANalysis System) a microcomputer-based analysis system for shipping cask design review: User`s manual to Version 3a. Volume 1, Revision 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mok, G.C.; Thomas, G.R.; Gerhard, M.A.

SCANS (Shipping Cask ANalysis System) is a microcomputer-based system of computer programs and databases developed at the Lawrence Livermore National Laboratory (LLNL) for evaluating safety analysis reports on spent fuel shipping casks. SCANS is an easy-to-use system that calculates the global response to impact loads, pressure loads and thermal conditions, providing reviewers with an independent check on analyses submitted by licensees. SCANS is based on microcomputers compatible with the IBM-PC family of computers. The system is composed of a series of menus, input programs, cask analysis programs, and output display programs. All data is entered through fill-in-the-blank input screens thatmore » contain descriptive data requests. Analysis options are based on regulatory cases described in the Code of Federal Regulations 10 CFR 71 and Regulatory Guides published by the US Nuclear Regulatory Commission in 1977 and 1978.« less

1992 NASA Life Support Systems Analysis workshop

NASA Technical Reports Server (NTRS)

Evanich, Peggy L.; Crabb, Thomas M.; Gartrell, Charles F.

1992-01-01

The 1992 Life Support Systems Analysis Workshop was sponsored by NASA's Office of Aeronautics and Space Technology (OAST) to integrate the inputs from, disseminate information to, and foster communication among NASA, industry, and academic specialists. The workshop continued discussion and definition of key issues identified in the 1991 workshop, including: (1) modeling and experimental validation; (2) definition of systems analysis evaluation criteria; (3) integration of modeling at multiple levels; and (4) assessment of process control modeling approaches. Through both the 1991 and 1992 workshops, NASA has continued to seek input from industry and university chemical process modeling and analysis experts, and to introduce and apply new systems analysis approaches to life support systems. The workshop included technical presentations, discussions, and interactive planning, with sufficient time allocated for discussion of both technology status and technology development recommendations. Key personnel currently involved with life support technology developments from NASA, industry, and academia provided input to the status and priorities of current and future systems analysis methods and requirements.

Analysis and design of a capsule landing system and surface vehicle control system for Mars exporation

NASA Technical Reports Server (NTRS)

Frederick, D. K.; Lashmet, P. K.; Sandor, G. N.; Shen, C. N.; Smith, E. J.; Yerazunis, S. W.

1972-01-01

The problems related to the design and control of a mobile planetary vehicle to implement a systematic plan for the exploration of Mars were investigated. Problem areas receiving attention include: vehicle configuration, control, dynamics, systems and propulsion; systems analysis; navigation, terrain modeling and path selection; and chemical analysis of specimens. The following specific tasks were studied: vehicle model design, mathematical modeling of dynamic vehicle, experimental vehicle dynamics, obstacle negotiation, electromechanical controls, collapsibility and deployment, construction of a wheel tester, wheel analysis, payload design, system design optimization, effect of design assumptions, accessory optimal design, on-board computer subsystem, laser range measurement, discrete obstacle detection, obstacle detection systems, terrain modeling, path selection system simulation and evaluation, gas chromatograph/mass spectrometer system concepts, chromatograph model evaluation and improvement and transport parameter evaluation.

Analysis and design of a capsule landing system and surface vehicle control system for Mars exploration

NASA Technical Reports Server (NTRS)

Frederick, D. K.; Lashmet, P. K.; Sandor, G. N.; Shen, C. N.; Smith, E. J.; Yerazunis, S. W.

1972-01-01

Investigation of problems related to the design and control of a mobile planetary vehicle to implement a systematic plan for the exploration of Mars has been undertaken. Problem areas receiving attention include: vehicle configuration, control, dynamics, systems and propulsion; systems analysis; terrain modeling and path selection; and chemical analysis of specimens. The following specific tasks have been under study: vehicle model design, mathematical modeling of a dynamic vehicle, experimental vehicle dynamics, obstacle negotiation, electromechanical controls, collapsibility and deployment, construction of a wheel tester, wheel analysis, payload design, system design optimization, effect of design assumptions, accessory optimal design, on-board computer sybsystem, laser range measurement, discrete obstacle detection, obstacle detection systems, terrain modeling, path selection system simulation and evaluation, gas chromatograph/mass spectrometer system concepts, chromatograph model evaluation and improvement.

Methodological aspects of fuel performance system analysis at raw hydrocarbon processing plants

NASA Astrophysics Data System (ADS)

Kulbjakina, A. V.; Dolotovskij, I. V.

2018-01-01

The article discusses the methodological aspects of fuel performance system analysis at raw hydrocarbon (RH) processing plants. Modern RH processing facilities are the major consumers of energy resources (ER) for their own needs. To reduce ER, including fuel consumption, and to develop rational fuel system structure are complex and relevant scientific tasks that can only be done using system analysis and complex system synthesis. In accordance with the principles of system analysis, the hierarchical structure of the fuel system, the block scheme for the synthesis of the most efficient alternative of the fuel system using mathematical models and the set of performance criteria have been developed on the main stages of the study. The results from the introduction of specific engineering solutions to develop their own energy supply sources for RH processing facilities have been provided.

Optimization of life support systems and their systems reliability

NASA Technical Reports Server (NTRS)

Fan, L. T.; Hwang, C. L.; Erickson, L. E.

1971-01-01

The identification, analysis, and optimization of life support systems and subsystems have been investigated. For each system or subsystem that has been considered, the procedure involves the establishment of a set of system equations (or mathematical model) based on theory and experimental evidences; the analysis and simulation of the model; the optimization of the operation, control, and reliability; analysis of sensitivity of the system based on the model; and, if possible, experimental verification of the theoretical and computational results. Research activities include: (1) modeling of air flow in a confined space; (2) review of several different gas-liquid contactors utilizing centrifugal force: (3) review of carbon dioxide reduction contactors in space vehicles and other enclosed structures: (4) application of modern optimal control theory to environmental control of confined spaces; (5) optimal control of class of nonlinear diffusional distributed parameter systems: (6) optimization of system reliability of life support systems and sub-systems: (7) modeling, simulation and optimal control of the human thermal system: and (8) analysis and optimization of the water-vapor eletrolysis cell.

Applications of High-speed motion analysis system on Solid Rocket Motor (SRM)

NASA Astrophysics Data System (ADS)

Liu, Yang; He, Guo-qiang; Li, Jiang; Liu, Pei-jin; Chen, Jian

2007-01-01

High-speed motion analysis system could record images up to 12,000fps and analyzed with the image processing system. The system stored data and images directly in electronic memory convenient for managing and analyzing. The high-speed motion analysis system and the X-ray radiography system were established the high-speed real-time X-ray radiography system, which could diagnose and measure the dynamic and high-speed process in opaque. The image processing software was developed for improve quality of the original image for acquiring more precise information. The typical applications of high-speed motion analysis system on solid rocket motor (SRM) were introduced in the paper. The research of anomalous combustion of solid propellant grain with defects, real-time measurement experiment of insulator eroding, explosion incision process of motor, structure and wave character of plume during the process of ignition and flameout, measurement of end burning of solid propellant, measurement of flame front and compatibility between airplane and missile during the missile launching were carried out using high-speed motion analysis system. The significative results were achieved through the research. Aim at application of high-speed motion analysis system on solid rocket motor, the key problem, such as motor vibrancy, electrical source instability, geometry aberrance, and yawp disturbance, which damaged the image quality, was solved. The image processing software was developed which improved the capability of measuring the characteristic of image. The experimental results showed that the system was a powerful facility to study instantaneous and high-speed process in solid rocket motor. With the development of the image processing technique, the capability of high-speed motion analysis system was enhanced.

A Model-Based Systems Engineering Methodology for Employing Architecture In System Analysis: Developing Simulation Models Using Systems Modeling Language Products to Link Architecture and Analysis

DTIC Science & Technology

2016-06-01

characteristics, experimental design techniques, and analysis methodologies that distinguish each phase of the MBSE MEASA. To ensure consistency... methodology . Experimental design selection, simulation analysis, and trade space analysis support the final two stages. Figure 27 segments the MBSE MEASA...rounding has the potential to increase the correlation between columns of the experimental design matrix. The design methodology presented in Vieira

Space Life-Support Engineering Program

NASA Technical Reports Server (NTRS)

Seagrave, Richard C. (Principal Investigator)

1995-01-01

This report covers the seventeen months of work performed under an extended one year NASA University Grant awarded to Iowa State University to perform research on topics relating to the development of closed-loop long-term life support systems with the initial principal focus on space water management. In the first phase of the program, investigators from chemistry and chemical engineering with demonstrated expertise in systems analysis, thermodynamics, analytical chemistry and instrumentation, performed research and development in two major related areas; the development of low-cost, accurate, and durable sensors for trace chemical and biological species, and the development of unsteady-state simulation packages for use in the development and optimization of control systems for life support systems. In the second year of the program, emphasis was redirected towards concentrating on the development of dynamic simulation techniques and software and on performing a thermodynamic systems analysis, centered on availability or energy analysis, in an effort to begin optimizing the systems needed for water purification. The third year of the program, the subject of this report, was devoted to the analysis of the water balance for the interaction between humans and the life support system during space flight and exercise, to analysis of the cardiopulmonary systems of humans during space flight, and to analysis of entropy production during operation of the air recovery system during space flight.

Try Fault Tree Analysis, a Step-by-Step Way to Improve Organization Development.

ERIC Educational Resources Information Center

Spitzer, Dean

1980-01-01

Fault Tree Analysis, a systems safety engineering technology used to analyze organizational systems, is described. Explains the use of logic gates to represent the relationship between failure events, qualitative analysis, quantitative analysis, and effective use of Fault Tree Analysis. (CT)

A Common Foundation of Information and Analytical Capability for AFSPC Decision Making

DTIC Science & Technology

2005-06-23

System Strategic Master Plan MAPs/MSP CRRAAF TASK FORCE CONOPS MUA Task Weights Engagement Analysis ASIIS Optimization ACEIT COST Analysis...Engangement Architecture Analysis Architecture MUA AFSPC POM S&T Planning Military Utility Analysis ACEIT COST Analysis Joint Capab Integ Develop System

CASKS (Computer Analysis of Storage Casks): A microcomputer based analysis system for storage cask review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, T.F.; Mok, G.C.; Carlson, R.W.

1996-12-01

CASKS is a microcomputer based computer system developed by LLNL to assist the Nuclear Regulatory Commission in performing confirmatory analyses for licensing review of radioactive-material storage cask designs. The analysis programs of the CASKS computer system consist of four modules--the impact analysis module, the thermal analysis module, the thermally-induced stress analysis module, and the pressure-induced stress analysis module. CASKS uses a series of menus to coordinate input programs, cask analysis programs, output programs, data archive programs and databases, so the user is able to run the system in an interactive environment. This paper outlines the theoretical background on the impactmore » analysis module and the yielding surface formulation. The close agreement between the CASKS analytical predictions and the results obtained form the two storage asks drop tests performed by SNL and by BNFL at Winfrith serves as the validation of the CASKS impact analysis module.« less

Casks (computer analysis of storage casks): A microcomputer based analysis system for storage cask review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, T.F.; Mok, G.C.; Carlson, R.W.

1995-08-01

CASKS is a microcomputer based computer system developed by LLNL to assist the Nuclear Regulatory Commission in performing confirmatory analyses for licensing review of radioactive-material storage cask designs. The analysis programs of the CASKS computer system consist of four modules: the impact analysis module, the thermal analysis module, the thermally-induced stress analysis module, and the pressure-induced stress analysis module. CASKS uses a series of menus to coordinate input programs, cask analysis programs, output programs, data archive programs and databases, so the user is able to run the system in an interactive environment. This paper outlines the theoretical background on themore » impact analysis module and the yielding surface formulation. The close agreement between the CASKS analytical predictions and the results obtained form the two storage casks drop tests performed by SNL and by BNFL at Winfrith serves as the validation of the CASKS impact analysis module.« less

A Systems Approach to Planning a Tele-Education System.

ERIC Educational Resources Information Center

Vazquez-Abad, Jesus; Mitchell, P. David

1983-01-01

Presents a systems analysis for transforming an educational system operating under a conventional scheme into a tele-education system. Particular attention is paid to developing and analyzing a preferred media mix and to the use of models and simulations as part of conducting a systems analysis. (Author)

Application of the Tool for Turbine Engine Closed-Loop Transient Analysis (TTECTrA) for Dynamic Systems Analysis

NASA Technical Reports Server (NTRS)

Csank, Jeffrey T.; Zinnecker, Alicia M.

2014-01-01

The aircraft engine design process seeks to achieve the best overall system-level performance, weight, and cost for a given engine design. This is achieved by a complex process known as systems analysis, where steady-state simulations are used to identify trade-offs that should be balanced to optimize the system. The steady-state simulations and data on which systems analysis relies may not adequately capture the true performance trade-offs that exist during transient operation. Dynamic Systems Analysis provides the capability for assessing these trade-offs at an earlier stage of the engine design process. The concept of dynamic systems analysis and the type of information available from this analysis are presented in this paper. To provide this capability, the Tool for Turbine Engine Closed-loop Transient Analysis (TTECTrA) was developed. This tool aids a user in the design of a power management controller to regulate thrust, and a transient limiter to protect the engine model from surge at a single flight condition (defined by an altitude and Mach number). Results from simulation of the closed-loop system may be used to estimate the dynamic performance of the model. This enables evaluation of the trade-off between performance and operability, or safety, in the engine, which could not be done with steady-state data alone. A design study is presented to compare the dynamic performance of two different engine models integrated with the TTECTrA software.

An Integrated Approach to Life Cycle Analysis

NASA Technical Reports Server (NTRS)

Chytka, T. M.; Brown, R. W.; Shih, A. T.; Reeves, J. D.; Dempsey, J. A.

2006-01-01

Life Cycle Analysis (LCA) is the evaluation of the impacts that design decisions have on a system and provides a framework for identifying and evaluating design benefits and burdens associated with the life cycles of space transportation systems from a "cradle-to-grave" approach. Sometimes called life cycle assessment, life cycle approach, or "cradle to grave analysis", it represents a rapidly emerging family of tools and techniques designed to be a decision support methodology and aid in the development of sustainable systems. The implementation of a Life Cycle Analysis can vary and may take many forms; from global system-level uncertainty-centered analysis to the assessment of individualized discriminatory metrics. This paper will focus on a proven LCA methodology developed by the Systems Analysis and Concepts Directorate (SACD) at NASA Langley Research Center to quantify and assess key LCA discriminatory metrics, in particular affordability, reliability, maintainability, and operability. This paper will address issues inherent in Life Cycle Analysis including direct impacts, such as system development cost and crew safety, as well as indirect impacts, which often take the form of coupled metrics (i.e., the cost of system unreliability). Since LCA deals with the analysis of space vehicle system conceptual designs, it is imperative to stress that the goal of LCA is not to arrive at the answer but, rather, to provide important inputs to a broader strategic planning process, allowing the managers to make risk-informed decisions, and increase the likelihood of meeting mission success criteria.

Building 865 Hypersonic Wind Tunnel Power System Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schneider, Larry X.

2015-02-01

This report documents the characterization and analysis of a high current power supply for the building 865 Hypersonic Wind Tunnel at Sandia National Laboratories. The system described in this report became operational in 2013, replacing the original 1968 system which employed an induction voltage regulator. This analysis and testing was completed to help the parent organization understand why an updated and redesigned power system was not delivering adequate power to resistive heater elements in the HWT. This analysis led to an improved understanding of the design and operation of the revised 2013 power supply system and identifies several reasons themore » revised system failed to achieve the performance of the original power supply installation. Design modifications to improve the performance of this system are discussed.« less

Soft error evaluation and vulnerability analysis in Xilinx Zynq-7010 system-on chip

NASA Astrophysics Data System (ADS)

Du, Xuecheng; He, Chaohui; Liu, Shuhuan; Zhang, Yao; Li, Yonghong; Xiong, Ceng; Tan, Pengkang

2016-09-01

Radiation-induced soft errors are an increasingly important threat to the reliability of modern electronic systems. In order to evaluate system-on chip's reliability and soft error, the fault tree analysis method was used in this work. The system fault tree was constructed based on Xilinx Zynq-7010 All Programmable SoC. Moreover, the soft error rates of different components in Zynq-7010 SoC were tested by americium-241 alpha radiation source. Furthermore, some parameters that used to evaluate the system's reliability and safety were calculated using Isograph Reliability Workbench 11.0, such as failure rate, unavailability and mean time to failure (MTTF). According to fault tree analysis for system-on chip, the critical blocks and system reliability were evaluated through the qualitative and quantitative analysis.

Computer-Aided Communication Satellite System Analysis and Optimization.

ERIC Educational Resources Information Center

Stagl, Thomas W.; And Others

Various published computer programs for fixed/broadcast communication satellite system synthesis and optimization are discussed. The rationale for selecting General Dynamics/Convair's Satellite Telecommunication Analysis and Modeling Program (STAMP) in modified form to aid in the system costing and sensitivity analysis work in the Program on…

System design of the Pioneer Venus spacecraft. Volume 3: Systems analysis

NASA Technical Reports Server (NTRS)

Fisher, J. N.

1973-01-01

The mission, systems, operations, ground systems, and reliability analysis of the Thor/Delta baseline design used for the Pioneer Space Probe are discussed. Tradeoff decisions concerning spin axis orientation, bus antenna design, communication system design, probe descent, and reduced science payload are analyzed. The reliability analysis is made for the probe bus mission, large probe mission, and small probe mission. Detailed mission sequences were established to identify critical areas and provide phasing of critical operation.

Sensitivity analysis as an aid in modelling and control of (poorly-defined) ecological systems. [closed ecological systems

NASA Technical Reports Server (NTRS)

Hornberger, G. M.; Rastetter, E. B.

1982-01-01

A literature review of the use of sensitivity analyses in modelling nonlinear, ill-defined systems, such as ecological interactions is presented. Discussions of previous work, and a proposed scheme for generalized sensitivity analysis applicable to ill-defined systems are included. This scheme considers classes of mathematical models, problem-defining behavior, analysis procedures (especially the use of Monte-Carlo methods), sensitivity ranking of parameters, and extension to control system design.

Design of a dual-mode electrochemical measurement and analysis system.

PubMed

Yang, Jr-Fu; Wei, Chia-Ling; Wu, Jian-Fu; Liu, Bin-Da

2013-01-01

A dual-mode electrochemical measurement and analysis system is proposed. This system includes a dual-mode chip, which was designed and fabricated by using TSMC 0.35 µm 3.3 V/5 V 2P4M mixed-signal CMOS process. Two electrochemical measurement and analysis methods, chronopotentiometry and voltammetry, can be performed by using the proposed chip and system. The proposed chip and system are verified successfully by performing voltammetry and chronopotentiometry on solutions.

Failure Mode, Effects, and Criticality Analysis (FMECA)

DTIC Science & Technology

1993-04-01

Preliminary Failure Modes, Effects and Criticality Analysis (FMECA) of the Brayton Isotope Power System Ground Demonstration System, Report No. TID 27301...No. TID/SNA - 3015, Aeroject Nuclear Systems Co., Sacramento, California: 1970. 95. Taylor , J.R. A Formalization of Failure Mode Analysis of Control...Roskilde, Denmark: 1973. 96. Taylor , J.R. A Semi-Automatic Method for Oualitative Failure Mode Analysis. Report No. RISO-M-1707. Available from a

A Mobile Computing Solution for Collecting Functional Analysis Data on a Pocket PC

PubMed Central

Jackson, James; Dixon, Mark R

2007-01-01

The present paper provides a task analysis for creating a computerized data system using a Pocket PC and Microsoft Visual Basic. With Visual Basic software and any handheld device running the Windows Moble operating system, this task analysis will allow behavior analysts to program and customize their own functional analysis data-collection system. The program will allow the user to select the type of behavior to be recorded, choose between interval and frequency data collection, and summarize data for graphing and analysis. We also provide suggestions for customizing the data-collection system for idiosyncratic research and clinical needs. PMID:17624078

Comfort and convenience analysis of advanced restraint systems

DOT National Transportation Integrated Search

1975-08-25

Five restraint systems were evaluated in terms of comfort and convenience by ten subjects. Statistical analysis of particular questions and system comparisons uncovered potential problems. The standard lap and shoulder belt system (1974 Chevrolet Imp...

Extreme Ultraviolet Imaging Telescope (EIT)

NASA Technical Reports Server (NTRS)

Lemen, J. R.; Freeland, S. L.

1997-01-01

Efforts concentrated on development and implementation of the SolarSoft (SSW) data analysis system. From an EIT analysis perspective, this system was designed to facilitate efficient reuse and conversion of software developed for Yohkoh/SXT and to take advantage of a large existing body of software developed by the SDAC, Yohkoh, and SOHO instrument teams. Another strong motivation for this system was to provide an EIT analysis environment which permits coordinated analysis of EIT data in conjunction with data from important supporting instruments, including Yohkoh/SXT and the other SOHO coronal instruments; CDS, SUMER, and LASCO. In addition, the SSW system will support coordinated EIT/TRACE analysis (by design) when TRACE data is available; TRACE launch is currently planned for March 1998. Working with Jeff Newmark, the Chianti software package (K.P. Dere et al) and UV /EUV data base was fully integrated into the SSW system to facilitate EIT temperature and emission analysis.

[Development of performance evaluation and management system on advanced schistosomiasis medical treatment].

PubMed

Zhou, Xiao-Rong; Huang, Shui-Sheng; Gong, Xin-Guo; Cen, Li-Ping; Zhang, Cong; Zhu, Hong; Yang, Jun-Jing; Chen, Li

2012-04-01

To construct a performance evaluation and management system on advanced schistosomiasis medical treatment, and analyze and evaluate the work of the advanced schistosomiasis medical treatment over the years. By applying the database management technique and C++ programming technique, we inputted the information of the advanced schistosomiasis cases into the system, and comprehensively evaluated the work of the advanced schistosomiasis medical treatment through the cost-effect analysis, cost-effectiveness analysis, and cost-benefit analysis. We made a set of software formula about cost-effect analysis, cost-effectiveness analysis, and cost-benefit analysis. This system had many features such as clear building, easy to operate, friendly surface, convenient information input and information search. It could benefit the performance evaluation of the province's advanced schistosomiasis medical treatment work. This system can satisfy the current needs of advanced schistosomiasis medical treatment work and can be easy to be widely used.

Miniaturized flow injection analysis system

DOEpatents

Folta, J.A.

1997-07-01

A chemical analysis technique known as flow injection analysis is described, wherein small quantities of chemical reagents and sample are intermixed and reacted within a capillary flow system and the reaction products are detected optically, electrochemically, or by other means. A highly miniaturized version of a flow injection analysis system has been fabricated utilizing microfabrication techniques common to the microelectronics industry. The microflow system uses flow capillaries formed by etching microchannels in a silicon or glass wafer followed by bonding to another wafer, commercially available microvalves bonded directly to the microflow channels, and an optical absorption detector cell formed near the capillary outlet, with light being both delivered and collected with fiber optics. The microflow system is designed mainly for analysis of liquids and currently measures 38{times}25{times}3 mm, but can be designed for gas analysis and be substantially smaller in construction. 9 figs.

Structured Analysis and the Data Flow Diagram: Tools for Library Analysis.

ERIC Educational Resources Information Center

Carlson, David H.

1986-01-01

This article discusses tools developed to aid the systems analysis process (program evaluation and review technique, Gantt charts, organizational charts, decision tables, flowcharts, hierarchy plus input-process-output). Similarities and differences among techniques, library applications of analysis, structured systems analysis, and the data flow…

Space crew radiation exposure analysis system based on a commercial stand-alone CAD system

NASA Technical Reports Server (NTRS)

Appleby, Matthew H.; Golightly, Michael J.; Hardy, Alva C.

1992-01-01

Major improvements have recently been completed in the approach to spacecraft shielding analysis. A Computer-Aided Design (CAD)-based system has been developed for determining the shielding provided to any point within or external to the spacecraft. Shielding analysis is performed using a commercially available stand-alone CAD system and a customized ray-tracing subroutine contained within a standard engineering modeling software package. This improved shielding analysis technique has been used in several vehicle design projects such as a Mars transfer habitat, pressurized lunar rover, and the redesigned Space Station. Results of these analyses are provided to demonstrate the applicability and versatility of the system.

Multi-Mission System Analysis for Planetary Entry (M-SAPE) Version 1

NASA Technical Reports Server (NTRS)

Samareh, Jamshid; Glaab, Louis; Winski, Richard G.; Maddock, Robert W.; Emmett, Anjie L.; Munk, Michelle M.; Agrawal, Parul; Sepka, Steve; Aliaga, Jose; Zarchi, Kerry;

IDIMS/GEOPAK: Users manual for a geophysical data display and analysis system

NASA Technical Reports Server (NTRS)

Libert, J. M.

1982-01-01

The application of an existing image analysis system to the display and analysis of geophysical data is described, the potential for expanding the capabilities of such a system toward more advanced computer analytic and modeling functions is investigated. The major features of the IDIMS (Interactive Display and Image Manipulation System) and its applicability for image type analysis of geophysical data are described. Development of a basic geophysical data processing system to permit the image representation, coloring, interdisplay and comparison of geophysical data sets using existing IDIMS functions and to provide for the production of hard copies of processed images was described. An instruction manual and documentation for the GEOPAK subsystem was produced. A training course for personnel in the use of the IDIMS/GEOPAK was conducted. The effectiveness of the current IDIMS/GEOPAK system for geophysical data analysis was evaluated.

A review of intelligent systems for heart sound signal analysis.

PubMed

Nabih-Ali, Mohammed; El-Dahshan, El-Sayed A; Yahia, Ashraf S

2017-10-01

Intelligent computer-aided diagnosis (CAD) systems can enhance the diagnostic capabilities of physicians and reduce the time required for accurate diagnosis. CAD systems could provide physicians with a suggestion about the diagnostic of heart diseases. The objective of this paper is to review the recent published preprocessing, feature extraction and classification techniques and their state of the art of phonocardiogram (PCG) signal analysis. Published literature reviewed in this paper shows the potential of machine learning techniques as a design tool in PCG CAD systems and reveals that the CAD systems for PCG signal analysis are still an open problem. Related studies are compared to their datasets, feature extraction techniques and the classifiers they used. Current achievements and limitations in developing CAD systems for PCG signal analysis using machine learning techniques are presented and discussed. In the light of this review, a number of future research directions for PCG signal analysis are provided.

Coal systems analysis: A new approach to the understanding of coal formation, coal quality and environmental considerations, and coal as a source rock for hydrocarbons

USGS Publications Warehouse

Warwick, Peter D.

2005-01-01

Coal is an important and required energy source for today's world. Current rates of world coal consumption are projected to continue at approximately the same (or greater) levels well into the twenty-first century. This paper will provide an introduction to the concept of coal systems analysis and the accompanying volume of papers will provide examples of how coal systems analysis can be used to understand, characterize, and evaluate coal and coal gas resources. Coal systems analysis incorporates the various disciplines of coal geology to provide a complete characterization of the resource. The coal system is divided into four stages: (1) accumulation, (2) preservation-burial, (3) diagenesis-coalification, and (4) coal and hydrocarbon resources. These stages are briefly discussed and key references and examples of the application of coal systems analysis are provided.

Test Analysis Guidelines

NASA Technical Reports Server (NTRS)

Jeng, Frank F.

2007-01-01

Development of analysis guidelines for Exploration Life Support (ELS) technology tests was completed. The guidelines were developed based on analysis experiences gained from supporting Environmental Control and Life Support System (ECLSS) technology development in air revitalization systems and water recovery systems. Analyses are vital during all three phases of the ELS technology test: pre-test, during test and post test. Pre-test analyses of a test system help define hardware components, predict system and component performances, required test duration, sampling frequencies of operation parameters, etc. Analyses conducted during tests could verify the consistency of all the measurements and the performance of the test system. Post test analyses are an essential part of the test task. Results of post test analyses are an important factor in judging whether the technology development is a successful one. In addition, development of a rigorous model for a test system is an important objective of any new technology development. Test data analyses, especially post test data analyses, serve to verify the model. Test analyses have supported development of many ECLSS technologies. Some test analysis tasks in ECLSS technology development are listed in the Appendix. To have effective analysis support for ECLSS technology tests, analysis guidelines would be a useful tool. These test guidelines were developed based on experiences gained through previous analysis support of various ECLSS technology tests. A comment on analysis from an experienced NASA ECLSS manager (1) follows: "Bad analysis was one that bent the test to prove that the analysis was right to begin with. Good analysis was one that directed where the testing should go and also bridged the gap between the reality of the test facility and what was expected on orbit."

Urban Planning and Management Information Systems Analysis and Design Based on GIS

NASA Astrophysics Data System (ADS)

Xin, Wang

Based on the analysis of existing relevant systems on the basis of inadequate, after a detailed investigation and research, urban planning and management information system will be designed for three-tier structure system, under the LAN using C/S mode architecture. Related functions for the system designed in accordance with the requirements of the architecture design of the functional relationships between the modules. Analysis of the relevant interface and design, data storage solutions proposed. The design for small and medium urban planning information system provides a viable building program.

Exergy Analysis of Rocket Systems

NASA Technical Reports Server (NTRS)

Gilbert, Andrew; Mesmer, Bryan; Watson, Michael D.

2015-01-01

Exergy is defined as the useful work available from a system in a specified environment. Exergy analysis allows for comparison between different system designs, and allows for comparison of subsystem efficiencies within system designs. The proposed paper explores the relationship between the fundamental rocket equation and an exergy balance equation. A previously derived exergy equation related to rocket systems is investigated, and a higher fidelity analysis will be derived. The exergy assessments will enable informed, value-based decision making when comparing alternative rocket system designs, and will allow the most efficient configuration among candidate configurations to be determined.

Attitude Determination Error Analysis System (ADEAS) mathematical specifications document

NASA Technical Reports Server (NTRS)

Nicholson, Mark; Markley, F.; Seidewitz, E.

1988-01-01

The mathematical specifications of Release 4.0 of the Attitude Determination Error Analysis System (ADEAS), which provides a general-purpose linear error analysis capability for various spacecraft attitude geometries and determination processes, are presented. The analytical basis of the system is presented. The analytical basis of the system is presented, and detailed equations are provided for both three-axis-stabilized and spin-stabilized attitude sensor models.

An Analysis of Turkey’s Defense Systems Acquisition Policy

DTIC Science & Technology

2009-03-01

i NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA MBA PROFESSIONAL REPORT An Analysis of Turkey’s Defense Systems Acquisition...2009 3. REPORT TYPE AND DATES COVERED MBA THESIS 4. TITLE AND SUBTITLE An Analysis of Turkey’s Defense Systems Acquisition Policy 6. AUTHOR(S...DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) The purpose of this MBA thesis is to analyze Turkey’s defense systems acquisition policy and