Sample records for anrep effect requires

  1. Brief Lags in Interrupted Sequential Performance: Evaluating a Model and Model Evaluation Method

    DTIC Science & Technology

    2015-01-05

    rehearsal mechanism in the model. To evaluate the model we developed a simple new goodness-of-fit test based on analysis of variance that offers an...repeated step). Sequen- tial constraints are common in medicine, equipment maintenance, computer programming and technical support, data analysis ...legal analysis , accounting, and many other home and workplace environ- ments. Sequential constraints also play a role in such basic cognitive processes

  2. [The history of cocaine in medicine and its importance to the discovery of the different forms of anaesthesia].

    PubMed

    Grzybowski, Andrzej

    2007-01-01

    The first description of the use of cocaine by humans can be found in the memoirs of the Florentine traveller Amerigo Vespucci (1451-1512). For the next 300 years mostly the advantages of cocaine use, also as a medication, were emphasized. In 1860 Albert Niemann (1834-1861) isolated an active ingredient of coca leaves, which he named cocaine. After his death, his work was carried on by his disciple Wilhelm Lossen (1838-1906), who finally, in 1865, determined its proper chemical formula. Although the first observations concerning the effect of cocaine on mucous membranes were made by Niemann and Lossen, the first experimental studies involving the application of cocaine to animals were performed by the Peruvian surgeon Moréno y Maïz. In 1880 Basil von Anrep (1852-1925) published the results of his studies concerning the application of cocaine to humans. In the conclusion of his work he recommended cocaine as a surgical anaesthesia. But it was finally Carl Koller (1857-1944) who, in 1884, empirically demonstrated the benefits of cocaine use in medicine, most of all in ophthalmology. Subsequently, within a couple of months, the medical world learnt about and got interested in the use of cocaine for local anaesthesia. William Stewart Halsted (1852-1922) and his collaborator Richard John Hall (1856-1897) began their own research on cocaine injections. Eventually they developed the nerve and regional blocking techniques. Nowadays, due to the potential harmful effects of cocaine and the risk of addiction, the indications for the use of cocaine as an anaesthetic are strictly limited.

  3. 10 CFR 5.125 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction § 5.125 Effect of other requirements. (a) Effect of... Congress or Federal regulation. (b) Effect of State or local law or other requirements. The obligation to... 10 Energy 1 2011-01-01 2011-01-01 false Effect of other requirements. 5.125 Section 5.125 Energy...

  4. 36 CFR 1211.125 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... FEDERAL FINANCIAL ASSISTANCE Introduction § 1211.125 Effect of other requirements. (a) Effect of other... regulation. (b) Effect of State or local law or other requirements. The obligation to comply with these Title..., on the basis of sex, to practice any occupation or profession. (c) Effect of rules or regulations of...

  5. 32 CFR 196.125 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... FEDERAL FINANCIAL ASSISTANCE Introduction § 196.125 Effect of other requirements. (a) Effect of other... regulation. (b) Effect of State or local law or other requirements. The obligation to comply with these Title..., on the basis of sex, to practice any occupation or profession. (c) Effect of rules or regulations of...

  6. 24 CFR 3.125 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... FINANCIAL ASSISTANCE Introduction § 3.125 Effect of other requirements. (a) Effect of other Federal... regulation. (b) Effect of State or local law or other requirements. The obligation to comply with these Title..., on the basis of sex, to practice any occupation or profession. (c) Effect of rules or regulations of...

  7. 24 CFR 200.640 - Effect on other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Effect on other requirements. 200... HOUSING AND URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Affirmative Fair Housing Marketing Regulations § 200.640 Effect on other requirements. The requirement for compliance with this part is in...

  8. 17 CFR 201.153 - Filing of papers: Signature requirement and effect.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Filing of papers: Signature requirement and effect. 201.153 Section 201.153 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... requirement and effect. (a) General requirements. Following the issuance of an order instituting proceedings...

  9. 21 CFR 1302.05 - Effective dates of labeling requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Effective dates of labeling requirements. 1302.05 Section 1302.05 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE LABELING AND PACKAGING REQUIREMENTS FOR CONTROLLED SUBSTANCES § 1302.05 Effective dates of labeling requirements. All...

  10. 45 CFR 618.125 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Effect of other requirements. 618.125 Section 618.125 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION... Introduction § 618.125 Effect of other requirements. (a) Effect of other Federal provisions. The obligations...

  11. 45 CFR 618.125 - Effect of other requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Effect of other requirements. 618.125 Section 618.125 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION... Introduction § 618.125 Effect of other requirements. (a) Effect of other Federal provisions. The obligations...

  12. 45 CFR 618.125 - Effect of other requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Effect of other requirements. 618.125 Section 618.125 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION... Introduction § 618.125 Effect of other requirements. (a) Effect of other Federal provisions. The obligations...

  13. 45 CFR 618.125 - Effect of other requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Effect of other requirements. 618.125 Section 618.125 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION... Introduction § 618.125 Effect of other requirements. (a) Effect of other Federal provisions. The obligations...

  14. 29 CFR 36.125 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction § 36.125 Effect of other requirements. (a) Effect of other Federal provisions. The obligations imposed by these Title IX regulations are independent... Act of Congress or Federal regulation. (b) Effect of State or local law or other requirements. The...

  15. 10 CFR 1042.125 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction § 1042.125 Effect of other requirements. (a) Effect of other Federal provisions. The obligations imposed by these Title IX regulations are... Act of Congress or Federal regulation. (b) Effect of State or local law or other requirements. The...

  16. 45 CFR 302.70 - Required State laws.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Required State laws. 302.70 Section 302.70 Public... PLAN REQUIREMENTS § 302.70 Required State laws. (a) Required Laws. The State plan shall provide that... effect laws providing for, and has implemented procedures to improve, program effectiveness: (1...

  17. 12 CFR 567.4 - Capital directives.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... requirement, the leverage ratio requirement, the tangible capital requirement, or individual minimum capital... capital directive, it may become effective immediately. A capital directive shall remain in effect and... plan shall continue in full force and effect. (b) Relation to other administrative actions. The Office...

  18. 76 FR 45181 - Enhancing Airline Passenger Protections: Limited Delay of Effective Date for Certain Provisions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-28

    ...The Department of Transportation is delaying the effective date for certain requirements adopted in an April 25, 2011 final rule on enhancing airline passenger protections. Specifically, the Department is delaying the effective date from August 23, 2011 to January 24, 2012, for requirements pertaining to baggage fees, post purchase price increases, flight status changes and holding a reservation without payment for twenty-four hours. The Department is also delaying the effective date from October 24, 2011 to January 24, 2012 for requirements pertaining to full fare advertising. The effective date remains August 23, 2011 for all the other requirements in the April 25, 2011 final rule, including the requirement not to permit an international flight to remain on the tarmac at a U.S. airport for more than four hours without allowing passengers to deplane, the requirement increasing the denied boarding compensation airlines must pay to passengers bumped from flights, and the requirement to disclose prominently all fees for optional aviation services on carriers' Web sites.

  19. 44 CFR 19.125 - Effect of other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction § 19.125 Effect of other requirements. (a... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Effect of other requirements. 19.125 Section 19.125 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY...

  20. 76 FR 80226 - Technical Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... final rule, effective upon publication. Generally, the Administrative Procedure Act (APA) requires a.... Additionally, the APA requires that a final rule must have a delayed effective date of 30 days from the date of... delayed effective date requirement under the APA. 5 U.S.C. 553(d)(3). Again the technical change conforms...

  1. 18 CFR 706.411 - Effect of statements on other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Effect of statements on other requirements. 706.411 Section 706.411 Conservation of Power and Water Resources WATER RESOURCES... Effect of statements on other requirements. The statements of employment and financial interests and...

  2. 18 CFR 706.411 - Effect of statements on other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Effect of statements on other requirements. 706.411 Section 706.411 Conservation of Power and Water Resources WATER RESOURCES... Effect of statements on other requirements. The statements of employment and financial interests and...

  3. 18 CFR 706.411 - Effect of statements on other requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Effect of statements on other requirements. 706.411 Section 706.411 Conservation of Power and Water Resources WATER RESOURCES... Effect of statements on other requirements. The statements of employment and financial interests and...

  4. 18 CFR 706.411 - Effect of statements on other requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Effect of statements on other requirements. 706.411 Section 706.411 Conservation of Power and Water Resources WATER RESOURCES... Effect of statements on other requirements. The statements of employment and financial interests and...

  5. 18 CFR 706.411 - Effect of statements on other requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Effect of statements on other requirements. 706.411 Section 706.411 Conservation of Power and Water Resources WATER RESOURCES... Effect of statements on other requirements. The statements of employment and financial interests and...

  6. 76 FR 66690 - Solid Urea From the Russian Federation: Final Results of Antidumping Duty Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    ...-Deposit Requirements The following cash-deposit requirements will be effective upon publication for all... Russian Federation. These cash-deposit requirements shall remain in effect until further notice... relevant entries during this review period. Failure to comply with this requirement could result in the...

  7. 41 CFR 101-8.304 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING FEDERAL FINANCIAL ASSISTANCE 8.3-Discrimination Prohibited on the Basis of Handicap § 101-8.304 Effect of State or local law or other requirements and effect... alleviated by the existence of any State or local law or other requirement that, on the basis of handicap...

  8. 41 CFR 101-8.304 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING FEDERAL FINANCIAL ASSISTANCE 8.3-Discrimination Prohibited on the Basis of Handicap § 101-8.304 Effect of State or local law or other requirements and effect... alleviated by the existence of any State or local law or other requirement that, on the basis of handicap...

  9. 41 CFR 101-8.304 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING FEDERAL FINANCIAL ASSISTANCE 8.3-Discrimination Prohibited on the Basis of Handicap § 101-8.304 Effect of State or local law or other requirements and effect... alleviated by the existence of any State or local law or other requirement that, on the basis of handicap...

  10. 41 CFR 101-8.304 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING FEDERAL FINANCIAL ASSISTANCE 8.3-Discrimination Prohibited on the Basis of Handicap § 101-8.304 Effect of State or local law or other requirements and effect... alleviated by the existence of any State or local law or other requirement that, on the basis of handicap...

  11. 41 CFR 101-8.304 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING FEDERAL FINANCIAL ASSISTANCE 8.3-Discrimination Prohibited on the Basis of Handicap § 101-8.304 Effect of State or local law or other requirements and effect... alleviated by the existence of any State or local law or other requirement that, on the basis of handicap...

  12. 12 CFR 1026.28 - Effect on state laws.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 9 2014-01-01 2014-01-01 false Effect on state laws. 1026.28 Section 1026.28... § 1026.28 Effect on state laws. (a) Inconsistent disclosure requirements. (1) Except as provided in paragraph (d) of this section, state law requirements that are inconsistent with the requirements contained...

  13. 7 CFR 1486.507 - What is the effect of failing to make required contributions?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false What is the effect of failing to make required..., Evaluation, and Compliance § 1486.507 What is the effect of failing to make required contributions? A... original ratio of private contributions to the authorized EMP funding level. ...

  14. 7 CFR 1486.507 - What is the effect of failing to make required contributions?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false What is the effect of failing to make required..., Evaluation, and Compliance § 1486.507 What is the effect of failing to make required contributions? A... original ratio of private contributions to the authorized EMP funding level. ...

  15. 7 CFR 1486.507 - What is the effect of failing to make required contributions?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false What is the effect of failing to make required..., Evaluation, and Compliance § 1486.507 What is the effect of failing to make required contributions? A... original ratio of private contributions to the authorized EMP funding level. ...

  16. 45 CFR 2516.830 - What types of activities are required of Corporation grantees to evaluate the effectiveness of...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Corporation grantees to evaluate the effectiveness of their subgrantees? 2516.830 Section 2516.830 Public... required of Corporation grantees to evaluate the effectiveness of their subgrantees? A Corporation grantee... reports. (c) Collect from programs and submit to the Corporation the descriptive information required in...

  17. 45 CFR 2516.830 - What types of activities are required of Corporation grantees to evaluate the effectiveness of...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Corporation grantees to evaluate the effectiveness of their subgrantees? 2516.830 Section 2516.830 Public... required of Corporation grantees to evaluate the effectiveness of their subgrantees? A Corporation grantee... reports. (c) Collect from programs and submit to the Corporation the descriptive information required in...

  18. 45 CFR 2516.830 - What types of activities are required of Corporation grantees to evaluate the effectiveness of...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Corporation grantees to evaluate the effectiveness of their subgrantees? 2516.830 Section 2516.830 Public... required of Corporation grantees to evaluate the effectiveness of their subgrantees? A Corporation grantee... reports. (c) Collect from programs and submit to the Corporation the descriptive information required in...

  19. 45 CFR 2516.830 - What types of activities are required of Corporation grantees to evaluate the effectiveness of...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Corporation grantees to evaluate the effectiveness of their subgrantees? 2516.830 Section 2516.830 Public... required of Corporation grantees to evaluate the effectiveness of their subgrantees? A Corporation grantee... reports. (c) Collect from programs and submit to the Corporation the descriptive information required in...

  20. 45 CFR 2516.830 - What types of activities are required of Corporation grantees to evaluate the effectiveness of...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Corporation grantees to evaluate the effectiveness of their subgrantees? 2516.830 Section 2516.830 Public... required of Corporation grantees to evaluate the effectiveness of their subgrantees? A Corporation grantee... reports. (c) Collect from programs and submit to the Corporation the descriptive information required in...

  1. Requirements based system risk modeling

    NASA Technical Reports Server (NTRS)

    Meshkat, Leila; Cornford, Steven; Feather, Martin

    2004-01-01

    The problem that we address in this paper is assessing the expected degree of success of the system or mission based on the degree to which each requirement is satisfied and the relative weight of the requirements. We assume a complete list of the requirements, the relevant risk elements and their probability of occurrence and the quantified effect of the risk elements on the requirements. In order to assess the degree to which each requirement is satisfied, we need to determine the effect of the various risk elements on the requirement.

  2. Do Stricter High School Graduation Requirements Improve College Readiness? ACT Working Paper Series. WP-2014-1

    ERIC Educational Resources Information Center

    Buddin, Richard; Croft, Michelle

    2014-01-01

    In recent years, state policymakers have increased high school course requirements--particularly in mathematics and science. This research examines whether stricter requirements have been effective at improving student outcomes. Student-level evidence from a state's recent reform suggests that higher requirements had little effect on trends in…

  3. 12 CFR Appendix C to Part 1030 - Effect on State Laws

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 9 2014-01-01 2014-01-01 false Effect on State Laws C Appendix C to Part 1030.... C Appendix C to Part 1030—Effect on State Laws (a) Inconsistent Requirements State law requirements... inconsistency. A state law is inconsistent if it requires a depository institution to make disclosures or take...

  4. Effects of Using Requirements Catalogs on Effectiveness and Productivity of Requirements Specification in a Software Project Management Course

    ERIC Educational Resources Information Center

    Fernández-Alemán, José Luis; Carrillo-de-Gea, Juan Manuel; Meca, Joaquín Vidal; Ros, Joaquín Nicolás; Toval, Ambrosio; Idri, Ali

    2016-01-01

    This paper presents the results of two educational experiments carried out to determine whether the process of specifying requirements (catalog-based reuse as opposed to conventional specification) has an impact on effectiveness and productivity in co-located and distributed software development environments. The participants in the experiments…

  5. Hypothermia for Patients Requiring Evacuation of Subdural Hematoma: Effect on Spreading Depolarizations

    DTIC Science & Technology

    2017-10-01

    AWARD NUMBER: W81XWH-16-C-0161 TITLE: Hypothermia for Patients Requiring Evacuation of Subdural Hematoma: Effect on Spreading Depolarizations...4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER W81XWH-16-C-0161 Hypothermia for Patients Requiring Evacuation of Subdural Hematoma: Effect on Spreading...in a sub-study of the HOPES trial to assess the effects of hypothermia on the pathologic mechanism of spreading depolarizations (SD). HOPES is a

  6. Nursing Home Staffing Requirements and Input Substitution: Effects on Housekeeping, Food Service, and Activities Staff

    PubMed Central

    Bowblis, John R; Hyer, Kathryn

    2013-01-01

    Objective To study the effect of minimum nurse staffing requirements on the subsequent employment of nursing home support staff. Data Sources Nursing home data from the Online Survey Certification and Reporting (OSCAR) System merged with state nurse staffing requirements. Study Design Facility-level housekeeping, food service, and activities staff levels are regressed on nurse staffing requirements and other controls using fixed effect panel regression. Data Extraction Method OSCAR surveys from 1999 to 2004. Principal Findings Increases in state direct care and licensed nurse staffing requirements are associated with decreases in the staffing levels of all types of support staff. Conclusions Increased nursing home nurse staffing requirements lead to input substitution in the form of reduced support staffing levels. PMID:23445455

  7. Nursing home staffing requirements and input substitution: effects on housekeeping, food service, and activities staff.

    PubMed

    Bowblis, John R; Hyer, Kathryn

    2013-08-01

    To study the effect of minimum nurse staffing requirements on the subsequent employment of nursing home support staff. Nursing home data from the Online Survey Certification and Reporting (OSCAR) System merged with state nurse staffing requirements. Facility-level housekeeping, food service, and activities staff levels are regressed on nurse staffing requirements and other controls using fixed effect panel regression. OSCAR surveys from 1999 to 2004. Increases in state direct care and licensed nurse staffing requirements are associated with decreases in the staffing levels of all types of support staff. Increased nursing home nurse staffing requirements lead to input substitution in the form of reduced support staffing levels. © Health Research and Educational Trust.

  8. 12 CFR Appendix C to Part 230 - Effect on State Laws

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Effect on State Laws C Appendix C to Part 230... (CONTINUED) TRUTH IN SAVINGS (REGULATION DD) Pt. 230, App. C Appendix C to Part 230—Effect on State Laws (a) Inconsistent Requirements State law requirements that are inconsistent with the requirements of the act and...

  9. 42 CFR 438.608 - Program integrity requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... compliance committee that are accountable to senior management. (3) Effective training and education for the compliance officer and the organization's employees. (4) Effective lines of communication between the... integrity requirements. (a) General requirement. The MCO or PIHP must have administrative and management...

  10. 42 CFR 438.608 - Program integrity requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... compliance committee that are accountable to senior management. (3) Effective training and education for the compliance officer and the organization's employees. (4) Effective lines of communication between the... integrity requirements. (a) General requirement. The MCO or PIHP must have administrative and management...

  11. The Modeling of Factors That Influence Coast Guard Manpower Requirements

    DTIC Science & Technology

    2014-12-01

    applications, and common data warehouses needed to fully develop an effective and efficient manpower requirements engineering and management program. The... manpower requirements determination ensures a ready force, and safe and effective mission execution. Shortage or excess of manpower is the catalyst...FACTORS THAT INFLUENCE COAST GUARD MANPOWER REQUIREMENTS by Kara M. Lavin December 2014 Thesis Advisor: Ronald E. Giachetti Co-Advisor

  12. 38 CFR 36.4209 - Reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... no further effect; Provided, nevertheless, That if the loan otherwise meets the requirements of this section, said certificate of commitment may be given effect by the Secretary, notwithstanding the report is received after the date otherwise required. (e) Subject to compliance with the regulations...

  13. 45 CFR 400.77 - Effect of quitting employment or failing or refusing to participate in required services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Effect of quitting employment or failing or... Employment General Requirements § 400.77 Effect of quitting employment or failing or refusing to participate... employment or fail or refuse to meet the requirements of § 400.75(a). [54 FR 5477, Feb. 3, 1989, as amended...

  14. 45 CFR 400.77 - Effect of quitting employment or failing or refusing to participate in required services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Effect of quitting employment or failing or... Employment General Requirements § 400.77 Effect of quitting employment or failing or refusing to participate... employment or fail or refuse to meet the requirements of § 400.75(a). [54 FR 5477, Feb. 3, 1989, as amended...

  15. 29 CFR 2590.731 - Preemption; State flexibility; construction.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... continues in effect any standard or requirement solely relating to health insurance issuers in connection with group health insurance coverage except to the extent that such standard or requirement prevents... establishes, implements, or continues in effect a standard or requirement applicable to imposition of a...

  16. 45 CFR 160.205 - Duration of effectiveness of exception determinations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... determinations. 160.205 Section 160.205 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATIVE DATA STANDARDS AND RELATED REQUIREMENTS GENERAL ADMINISTRATIVE REQUIREMENTS Preemption of State Law... remains in effect until: (a) Either the State law or the federal standard, requirement, or implementation...

  17. 24 CFR 35.84 - Effective dates.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... The requirements in this subpart take effect in the following manner: (a) For owners of more than four residential dwellings, the requirements shall take effect on September 6, 1996. (b) For owners of one to four...

  18. 78 FR 44559 - Effective Date of Revised Company Registration Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-24

    ... are registered to make that type of filing. \\1\\ Revisions to Company Registration and Establishing...; and RM12-3-000] Effective Date of Revised Company Registration Requirements AGENCY: Federal Energy... Revised Company Registration Requirements. The Commission issued a Notice in the Federal Register, 78 FR...

  19. Use of randomised controlled trials for producing cost-effectiveness evidence: potential impact of design choices on sample size and study duration.

    PubMed

    Backhouse, Martin E

    2002-01-01

    A number of approaches to conducting economic evaluations could be adopted. However, some decision makers have a preference for wholly stochastic cost-effectiveness analyses, particularly if the sampled data are derived from randomised controlled trials (RCTs). Formal requirements for cost-effectiveness evidence have heightened concerns in the pharmaceutical industry that development costs and times might be increased if formal requirements increase the number, duration or costs of RCTs. Whether this proves to be the case or not will depend upon the timing, nature and extent of the cost-effectiveness evidence required. To illustrate how different requirements for wholly stochastic cost-effectiveness evidence could have a significant impact on two of the major determinants of new drug development costs and times, namely RCT sample size and study duration. Using data collected prospectively in a clinical evaluation, sample sizes were calculated for a number of hypothetical cost-effectiveness study design scenarios. The results were compared with a baseline clinical trial design. The sample sizes required for the cost-effectiveness study scenarios were mostly larger than those for the baseline clinical trial design. Circumstances can be such that a wholly stochastic cost-effectiveness analysis might not be a practical proposition even though its clinical counterpart is. In such situations, alternative research methodologies would be required. For wholly stochastic cost-effectiveness analyses, the importance of prior specification of the different components of study design is emphasised. However, it is doubtful whether all the information necessary for doing this will typically be available when product registration trials are being designed. Formal requirements for wholly stochastic cost-effectiveness evidence based on the standard frequentist paradigm have the potential to increase the size, duration and number of RCTs significantly and hence the costs and timelines associated with new product development. Moreover, it is possible to envisage situations where such an approach would be impossible to adopt. Clearly, further research is required into the issue of how to appraise the economic consequences of alternative economic evaluation research strategies.

  20. 29 CFR 453.25 - Effective date of the bonding requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Effective date of the bonding requirement. 453.25 Section 453.25 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT STANDARDS GENERAL STATEMENT CONCERNING THE BONDING REQUIREMENTS OF THE LABOR-MANAGEMENT...

  1. 29 CFR 453.25 - Effective date of the bonding requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 2 2011-07-01 2011-07-01 false Effective date of the bonding requirement. 453.25 Section 453.25 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT STANDARDS GENERAL STATEMENT CONCERNING THE BONDING REQUIREMENTS OF THE LABOR-MANAGEMENT...

  2. Seeing the Elephant -- Consequence Management Policy for the Department of Defense

    DTIC Science & Technology

    2001-05-01

    required for effective Consequence Management. The three response tiers allows the DoD to provide a predesignated level of support to the appropriate Federal...recommendation is the creation of a tiered response capability that balances time and tasks required for effective Consequence Management. The three...the response required for toxic chemical events. The third tier is reserved for the actions required for the Consequence Management for a biological

  3. Radiation Requirements and Requirements Flowdown: Single Event Effects (SEEs) and Requirements

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.

    2002-01-01

    This short course session provides: (1) an overview of the single particle-induced hazard for space system as they apply in the natural space environment. This shall focus on the implementation of a single event effect hardness assurance (SEEHA) program for systems including system engineering approach and mitigation of effects. (2) The final portion of this session shell provide relevant real-life examples of in-flight performance of systems.

  4. Closed Loop Requirements and Analysis Management

    NASA Technical Reports Server (NTRS)

    Lamoreaux, Michael; Verhoef, Brett

    2015-01-01

    Effective systems engineering involves the use of analysis in the derivation of requirements and verification of designs against those requirements. The initial development of requirements often depends on analysis for the technical definition of specific aspects of a product. Following the allocation of system-level requirements to a product's components, the closure of those requirements often involves analytical approaches to verify that the requirement criteria have been satisfied. Meanwhile, changes that occur in between these two processes need to be managed in order to achieve a closed-loop requirement derivation/verification process. Herein are presented concepts for employing emerging Team center capabilities to jointly manage requirements and analysis data such that analytical techniques are utilized to effectively derive and allocate requirements, analyses are consulted and updated during the change evaluation processes, and analyses are leveraged during the design verification process. Recommendations on concept validation case studies are also discussed.

  5. 22 CFR 229.125 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of 1963 (29 U.S.C. 206); and any other Act of Congress or Federal regulation. (b) Effect of State or... any occupation or profession. (c) Effect of rules or regulations of private organizations. The... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Effect of other requirements. 229.125 Section...

  6. 28 CFR 54.125 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of 1963 (29 U.S.C. 206); and any other Act of Congress or Federal regulation. (b) Effect of State or... any occupation or profession. (c) Effect of rules or regulations of private organizations. The... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Effect of other requirements. 54.125...

  7. 45 CFR 605.10 - Effect of state or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Effect of state or local law or other requirements and effect of employment opportunities. 605.10 Section 605.10 Public Welfare Regulations Relating to... PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 605.10 Effect of state...

  8. 45 CFR 605.10 - Effect of state or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Effect of state or local law or other requirements and effect of employment opportunities. 605.10 Section 605.10 Public Welfare Regulations Relating to... PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 605.10 Effect of state...

  9. 10 CFR 611.106 - Environmental requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... significant environmental effects expected to occur as a result of the project; (3) Identify the effects of... cumulative effects resulting from existing or reasonably foreseeable projects; (4) Identify measures proposed... on-site manpower requirements and payroll during construction and operation, including the number of...

  10. 10 CFR 611.106 - Environmental requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... significant environmental effects expected to occur as a result of the project; (3) Identify the effects of... cumulative effects resulting from existing or reasonably foreseeable projects; (4) Identify measures proposed... on-site manpower requirements and payroll during construction and operation, including the number of...

  11. 10 CFR 611.106 - Environmental requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... significant environmental effects expected to occur as a result of the project; (3) Identify the effects of... cumulative effects resulting from existing or reasonably foreseeable projects; (4) Identify measures proposed... on-site manpower requirements and payroll during construction and operation, including the number of...

  12. 10 CFR 611.106 - Environmental requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... significant environmental effects expected to occur as a result of the project; (3) Identify the effects of... cumulative effects resulting from existing or reasonably foreseeable projects; (4) Identify measures proposed... on-site manpower requirements and payroll during construction and operation, including the number of...

  13. 10 CFR 611.106 - Environmental requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... significant environmental effects expected to occur as a result of the project; (3) Identify the effects of... cumulative effects resulting from existing or reasonably foreseeable projects; (4) Identify measures proposed... on-site manpower requirements and payroll during construction and operation, including the number of...

  14. On the Compliance of Simbol-X Mirror Roughness with its Effective Area Requirements

    NASA Astrophysics Data System (ADS)

    Spiga, D.; Basso, S.; Cotroneo, V.; Pareschi, G.; Tagliaferri, G.

    2009-05-01

    Surface microroughness of X-ray mirrors is a key issue for the angular resolution of Simbol-X to comply with the required one (<20 arcsec at 30 keV). The maximum tolerable microroughness for Simbol-X mirrors, in order to satisfy the required imaging capability, has already been derived in terms of its PSD (Power Spectral Density). However, also the Effective Area of the telescope is affected by the mirror roughness. In this work we will show how the expected effective area of the Simbol-X mirror module can be computed from the roughness PSD tolerance, checking its compliance with the requirements.

  15. Sunk cost and work ethic effects reflect suboptimal choice between different work requirements.

    PubMed

    Magalhães, Paula; White, K Geoffrey

    2013-03-01

    We investigated suboptimal choice between different work requirements in pigeons (Columba livia), namely the sunk cost effect, an irrational tendency to persist with an initial investment, despite the availability of a better option. Pigeons chose between two keys, one with a fixed work requirement to food of 20 pecks (left key), and the other with a work requirement to food which varied across conditions (center key). On some trials within each session, such choices were preceded by an investment of 35 pecks on the center key, whereas on others they were not. On choice trials preceded by the investment, the pigeons tended to stay and complete the schedule associated with the center key, even when the number of pecks to obtain reward was greater than for the concurrently available left key. This result indicates that pigeons, like humans, commit the sunk cost effect. With higher work requirements, this preference was extended to trials where there was no initial investment, so an overall preference for the key associated with more work was evident, consistent with the work ethic effect. We conclude that a more general work ethic effect is amplified by the effect of the prior investment, that is, the sunk cost effect. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. 21 CFR 209.1 - Scope and purpose.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... REQUIREMENT FOR AUTHORIZED DISPENSERS AND PHARMACIES TO DISTRIBUTE A SIDE EFFECTS STATEMENT General Provisions... dispensers and pharmacies to consumers. This part requires distribution of a side effects statement and...

  17. 21 CFR 209.1 - Scope and purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... REQUIREMENT FOR AUTHORIZED DISPENSERS AND PHARMACIES TO DISTRIBUTE A SIDE EFFECTS STATEMENT General Provisions... dispensers and pharmacies to consumers. This part requires distribution of a side effects statement and...

  18. 21 CFR 209.1 - Scope and purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... REQUIREMENT FOR AUTHORIZED DISPENSERS AND PHARMACIES TO DISTRIBUTE A SIDE EFFECTS STATEMENT General Provisions... dispensers and pharmacies to consumers. This part requires distribution of a side effects statement and...

  19. 21 CFR 209.1 - Scope and purpose.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... REQUIREMENT FOR AUTHORIZED DISPENSERS AND PHARMACIES TO DISTRIBUTE A SIDE EFFECTS STATEMENT General Provisions... dispensers and pharmacies to consumers. This part requires distribution of a side effects statement and...

  20. 21 CFR 209.1 - Scope and purpose.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... REQUIREMENT FOR AUTHORIZED DISPENSERS AND PHARMACIES TO DISTRIBUTE A SIDE EFFECTS STATEMENT General Provisions... dispensers and pharmacies to consumers. This part requires distribution of a side effects statement and...

  1. 20 CFR 416.1725 - Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... treatment requirements for your drug addiction or alcoholism. 416.1725 Section 416.1725 Employees' Benefits... Or Drug Addiction § 416.1725 Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism. (a) Suspension of benefits. Your eligibility for benefits will be...

  2. 20 CFR 416.1725 - Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... treatment requirements for your drug addiction or alcoholism. 416.1725 Section 416.1725 Employees' Benefits... Or Drug Addiction § 416.1725 Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism. (a) Suspension of benefits. Your eligibility for benefits will be...

  3. 20 CFR 416.1725 - Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... treatment requirements for your drug addiction or alcoholism. 416.1725 Section 416.1725 Employees' Benefits... Or Drug Addiction § 416.1725 Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism. (a) Suspension of benefits. Your eligibility for benefits will be...

  4. 20 CFR 416.1725 - Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... treatment requirements for your drug addiction or alcoholism. 416.1725 Section 416.1725 Employees' Benefits... Or Drug Addiction § 416.1725 Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism. (a) Suspension of benefits. Your eligibility for benefits will be...

  5. Thermionic reactor power conditioner design for nuclear electric propulsion.

    NASA Technical Reports Server (NTRS)

    Jacobsen, A. S.; Tasca, D. M.

    1971-01-01

    Consideration of the effects of various thermionic reactor parameters and requirements upon spacecraft power conditioning design. A basic spacecraft is defined using nuclear electric propulsion, requiring approximately 120 kWe. The interrelationships of reactor operating characteristics and power conditioning requirements are discussed and evaluated, and the effects on power conditioner design and performance are presented.

  6. Effectiveness of Selected Teaching Strategies in Relation to the Learning Styles of Secondary School Students in India

    ERIC Educational Resources Information Center

    Kamboj, Pooja; Singh, Sushil Kumar

    2015-01-01

    Effective teaching in schools requires flexibility, energy and commitment. Successful teaching also requires that teachers are able to address learner's needs and understand the variations in learner's styles and approaches. Teachers can accomplish these requirements while creating an optimal teaching-learning environment by utilizing a variety of…

  7. Maryland's Graduation Requirements: Local Effects of Policy Reform.

    ERIC Educational Resources Information Center

    Wilson, Bruce L.; And Others

    In 1985, Maryland became one of 45 states that enacted new and tougher graduation requirements. This document presents findings of a 4-year study that examined the effects of the new requirements on local schools and the students and staff who work in them. Three site visits each were made to five selected high schools. Data collection included:…

  8. Human Papillomavirus Vaccination Requirements in US Schools: Recommendations for Moving Forward.

    PubMed

    North, Anna L; Niccolai, Linda M

    2016-10-01

    Safe and effective human papillomavirus (HPV) vaccines have been available and recommended for adolescents for a decade in the United States, yet vaccination rates remain suboptimal. School entry requirements have increased uptake of other vaccines for adolescents and made coverage more equitable. However, only 3 jurisdictions require HPV vaccine for school. We summarize the current status of HPV vaccine requirements and discuss the rationales for and against these policies. The rationales for requirements include HPV vaccine efficacy and safety, effectiveness of requirements for increasing vaccine uptake and making it more equitable, and use of requirements as "safety nets" and to achieve herd immunity. The rationales against requirements include low parental acceptance of HPV vaccine, the financial burden on educational systems and health departments, and the possibility for alternatives to increase vaccine uptake. Many challenges to HPV vaccine requirements are addressable, and we conclude with recommendations on how to approach these challenges.

  9. 49 CFR 805.735-22 - Effect of statements on other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 7 2011-10-01 2011-10-01 false Effect of statements on other requirements. 805.735-22 Section 805.735-22 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL TRANSPORTATION SAFETY BOARD EMPLOYEE RESPONSIBILITIES AND CONDUCT § 805.735-22 Effect of...

  10. 45 CFR 86.6 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... any occupation or profession. (c) Effect of rules or regulations of private organizations. The... 45 Public Welfare 1 2011-10-01 2011-10-01 false Effect of other requirements. 86.6 Section 86.6... BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction...

  11. 49 CFR 805.735-22 - Effect of statements on other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Effect of statements on other requirements. 805.735-22 Section 805.735-22 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL TRANSPORTATION SAFETY BOARD EMPLOYEE RESPONSIBILITIES AND CONDUCT § 805.735-22 Effect of...

  12. The Technique of Special Effects in Television.

    ERIC Educational Resources Information Center

    Wilkie, Bernard

    Television, with its special need for movement and continuous shooting, often demands different special effects techniques from those used in films. This book covers the techniques used to create special effects for television which meet these requirements and which also require less time and money than many film techniques. Included are…

  13. 41 CFR 101-4.125 - Effect of other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction § 101-4.125 Effect of... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Effect of other requirements. 101-4.125 Section 101-4.125 Public Contracts and Property Management Federal Property Management...

  14. 18 CFR 376.208 - Effect upon existing Commission requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Effect upon existing Commission requirements. 376.208 Section 376.208 Conservation of Power and Water Resources FEDERAL ENERGY...; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.208 Effect upon...

  15. 18 CFR 376.208 - Effect upon existing Commission requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Effect upon existing Commission requirements. 376.208 Section 376.208 Conservation of Power and Water Resources FEDERAL ENERGY...; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.208 Effect upon...

  16. 18 CFR 376.208 - Effect upon existing Commission requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Effect upon existing Commission requirements. 376.208 Section 376.208 Conservation of Power and Water Resources FEDERAL ENERGY...; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.208 Effect upon...

  17. 18 CFR 376.208 - Effect upon existing Commission requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Effect upon existing Commission requirements. 376.208 Section 376.208 Conservation of Power and Water Resources FEDERAL ENERGY...; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.208 Effect upon...

  18. 18 CFR 376.208 - Effect upon existing Commission requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Effect upon existing Commission requirements. 376.208 Section 376.208 Conservation of Power and Water Resources FEDERAL ENERGY...; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.208 Effect upon...

  19. 40 CFR 1043.5 - Effective dates.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Effective dates. 1043.5 Section 1043.5... Effective dates. (a) The requirement of APPS for marine vessels to comply with Annex VI of the MARPOL... 1, 2010, although some requirements do not become applicable until later dates. (c) Compliance with...

  20. [Spatial and temporal characteristics of flue-cured tobacco water requirement and irrigation requirement index in Yunnan Province, China].

    PubMed

    Zheng, Dong-fang; Xu, Jia-yang; Lu, Xiu-ping; Xu, Zi-cheng; Li, Jun-ying; Pang, Tao; Zhang, Ya-jie; Wang, Pei-wen

    2015-07-01

    Based on the daily meteorological data of 124 agricultural meteorological sites during 1977-2010 in Yunnan Province, using recommended Penman-Monteith formula by FAO, water requirement and irrigation requirement index in the growth period of flue-cured tobacco were calculated to analyze their spatial and temporal characteristics and change patterns. The results showed that water requirements of flue-cured tobacco in root extending, vigorous, mature periods and field growth period during 1977-2010 were 76.73-174.73, 247.50-386.64, 180.28-258.14 and 528.18-764.08 mm, respectively, and the water requirement of vigorous period was the highest. The average irrigation demand index of each period was -0.02, 0.38, 0.17 and 0.26, respectively. Effective precipitation could meet the demand of flue-cured tobacco in root extending period. Water requirement of flue-cured tobacco in Yunnan Province decreased annually, and the rates of water requirement under the climate change trend in the four periods abovementioned were -12. 42, -21.46, -7.17 and -47.15 mm . (10 a)-1, respectively. The smallest irrigation demand index was observed in Dehong, and the largest in Diqing. The irrigation demand indexes of Dehong, Xishuangbanna and Puer regions were negative in flue-cured tobacco field growth period. The reference crop evapotranspiration, water requirement and effective precipitation decreased, but the irrigation requirement and irrigation requirement index increased with the increase of latitude. The effective precipitation decreased, but the irrigation requirement and irrigation requirement index increased with the increase of altitude.

  1. 48 CFR 2132.771 - Non-commingling of FEGLI Program funds.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... REQUIREMENTS CONTRACT FINANCING Contract Funding 2132.771 Non-commingling of FEGLI Program funds. (a) FEGLI... other controls are in effect. If the requirement is modified, such modification will remain in effect...

  2. 48 CFR 2132.771 - Non-commingling of FEGLI Program funds.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... REQUIREMENTS CONTRACT FINANCING Contract Funding 2132.771 Non-commingling of FEGLI Program funds. (a) FEGLI... other controls are in effect. If the requirement is modified, such modification will remain in effect...

  3. 48 CFR 2132.771 - Non-commingling of FEGLI Program funds.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... REQUIREMENTS CONTRACT FINANCING Contract Funding 2132.771 Non-commingling of FEGLI Program funds. (a) FEGLI... other controls are in effect. If the requirement is modified, such modification will remain in effect...

  4. 48 CFR 2132.771 - Non-commingling of FEGLI Program funds.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... REQUIREMENTS CONTRACT FINANCING Contract Funding 2132.771 Non-commingling of FEGLI Program funds. (a) FEGLI... other controls are in effect. If the requirement is modified, such modification will remain in effect...

  5. 48 CFR 2132.771 - Non-commingling of FEGLI Program funds.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... REQUIREMENTS CONTRACT FINANCING Contract Funding 2132.771 Non-commingling of FEGLI Program funds. (a) FEGLI... other controls are in effect. If the requirement is modified, such modification will remain in effect...

  6. Theoretical requirements for broadband perfect absorption of acoustic waves by ultra-thin elastic meta-films

    PubMed Central

    Duan, Yuetao; Luo, Jie; Wang, Guanghao; Hang, Zhi Hong; Hou, Bo; Li, Jensen; Sheng, Ping; Lai, Yun

    2015-01-01

    We derive and numerically demonstrate that perfect absorption of elastic waves can be achieved in two types of ultra-thin elastic meta-films: one requires a large value of almost pure imaginary effective mass density and a free space boundary, while the other requires a small value of almost pure imaginary effective modulus and a hard wall boundary. When the pure imaginary density or modulus exhibits certain frequency dispersions, the perfect absorption effect becomes broadband, even in the low frequency regime. Through a model analysis, we find that such almost pure imaginary effective mass density with required dispersion for perfect absorption can be achieved by elastic metamaterials with large damping. Our work provides a feasible approach to realize broadband perfect absorption of elastic waves in ultra-thin films. PMID:26184117

  7. Impact of science objectives and requirements on probe mission and system design

    NASA Technical Reports Server (NTRS)

    Ledbetter, K. W.

    1974-01-01

    Problem areas in probe science technology are discussed that require a solution before probe systems can actually be designed. Considered are the effects of the model atmospheres on probe design; secondly, the effects of implementing the requirements to locate and measure the clouds and, trade-offs between descent sampling and measurement criteria as they affect probe system design.

  8. 38 CFR 18.410 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Effect of State or local law or other requirements and effect of employment opportunities. 18.410 Section 18.410 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) NONDISCRIMINATION IN FEDERALLY-ASSISTED PROGRAMS OF THE DEPARTMENT OF VETERANS...

  9. 22 CFR 217.10 - Effect of state or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Effect of state or local law or other requirements and effect of employment opportunities. 217.10 Section 217.10 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions §...

  10. Fertilizer effects on attaining vegetation requirements.

    DOT National Transportation Integrated Search

    2014-02-01

    This project was developed to evaluate the effects of varying the substrate and fertilization regimes on the success of complex warm-season grass and forb seedings on recent roadside construction sites. Re-vegetating construction projects is required...

  11. Assessing the effect of disease on nutrition of the preterm infant.

    PubMed

    Hay, W W

    1996-10-01

    To review existing data on nutritional requirements of extremely low birth weight (ELBW) and very low birth weight (VLBW) preterm infants (those who weigh < 1000 g and 1000-1500 g at birth, respectively), and the effects of diseases on these nutritional requirements. A literature search was conducted on applicable articles related to nutritional requirements of preterm ELBW and VLBW infants and the effects of diseases in these infants on their nutritional and metabolic requirements. The literature was analyzed to determine nutritional requirements of preterm ELBW and VLBW infants, to select the most common diseases that have significant and important effects on nutrition and metabolism in these infants, and to make recommendations about diagnostic and therapeutic approaches to nutritional problems as affected by diseases in ELBW and VLBW infants. Many diseases unique to preterm infants, either directly or by enhancing the effects of stress on the metabolism of such infants, provide important changes in the nutrient requirements. The overriding observation from all studies, however, is that ELBW and VLBW preterm infants are underfed during the early postnatal period and that this condition, combined with additional stresses from various diseases, increases the risk of long-term neurological sequelae. The value of achieving a specific body composition and growth weight is less certain. There remains a critical need for determining the right quality as well as quantity of nutrients for these infants.

  12. Section 5: Adapting Requirements Practices in Different Domains

    NASA Astrophysics Data System (ADS)

    Robinson, William

    Technology has a tremendous impact on society. In recent years, the Internet, World Wide Web, and Web 2.0 has changed the nature of commerce, government, and of course software development. It affects the practices of producing requirements and as well as the kinds of systems to be designed. The effect of converging technologies on the role of requirements engineering is considered in the first article by Matthias Jarke, while the effect of technology on requirements practices is considered in the second article by Walt Scacchi. Together, they provide theoretical and practical perspective on requirements engineering issues faced in a modern, technology driven world.

  13. 21 CFR 876.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Effective dates of requirement for premarket approval. 876.3 Section 876.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES General Provisions § 876.3 Effective...

  14. 12 CFR 226.28 - Effect on State laws.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 3 2013-01-01 2013-01-01 false Effect on State laws. 226.28 Section 226.28... (CONTINUED) TRUTH IN LENDING (REGULATION Z) Miscellaneous § 226.28 Effect on State laws. (a) Inconsistent disclosure requirements. (1) Except as provided in paragraph (d) of this section, State law requirements that...

  15. 12 CFR 226.28 - Effect on State laws.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Effect on State laws. 226.28 Section 226.28... TRUTH IN LENDING (REGULATION Z) Miscellaneous § 226.28 Effect on State laws. (a) Inconsistent disclosure requirements. (1) Except as provided in paragraph (d) of this section, State law requirements that are...

  16. 21 CFR 872.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Effective dates of requirement for premarket approval. 872.3 Section 872.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES DENTAL DEVICES General Provisions § 872.3 Effective dates of...

  17. 21 CFR 872.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Effective dates of requirement for premarket approval. 872.3 Section 872.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES DENTAL DEVICES General Provisions § 872.3 Effective dates of...

  18. 21 CFR 888.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Effective dates of requirement for premarket approval. 888.3 Section 888.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ORTHOPEDIC DEVICES General Provisions § 888.3 Effective dates of...

  19. 21 CFR 888.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Effective dates of requirement for premarket approval. 888.3 Section 888.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ORTHOPEDIC DEVICES General Provisions § 888.3 Effective dates of...

  20. 21 CFR 888.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Effective dates of requirement for premarket approval. 888.3 Section 888.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ORTHOPEDIC DEVICES General Provisions § 888.3 Effective dates of...

  1. 21 CFR 888.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Effective dates of requirement for premarket approval. 888.3 Section 888.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ORTHOPEDIC DEVICES General Provisions § 888.3 Effective dates of...

  2. 21 CFR 888.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Effective dates of requirement for premarket approval. 888.3 Section 888.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ORTHOPEDIC DEVICES General Provisions § 888.3 Effective dates of...

  3. Where to Start with Pesticide Incidents

    Science.gov Websites

    . Manufacturers are required by law to submit reports of adverse effects to the US EPA. Attention Physicians and . Manufacturers are required by law to submit reports of adverse effects to the US EPA. Consider contacting your . Please submit reports using our quick and easy Veterinary Pesticide Adverse Effects Reporting portal

  4. Report Card on the Effectiveness of Teacher Training Programs

    ERIC Educational Resources Information Center

    Tennessee State Board of Education, 2010

    2010-01-01

    Tennessee Code Annotated 49-5-108 requires the state to develop a report card or assessment on the effectiveness of teacher training programs. This report includes data on the performance of each institution's graduates in the following areas required by state statute: placement and retention rates, Praxis results, and teacher effect data based on…

  5. 21 CFR 864.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Effective dates of requirement for premarket approval. 864.3 Section 864.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES General Provisions § 864.3 Effective...

  6. 21 CFR 864.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Effective dates of requirement for premarket approval. 864.3 Section 864.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES General Provisions § 864.3 Effective...

  7. 21 CFR 864.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Effective dates of requirement for premarket approval. 864.3 Section 864.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES General Provisions § 864.3 Effective...

  8. 21 CFR 864.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Effective dates of requirement for premarket approval. 864.3 Section 864.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES General Provisions § 864.3 Effective...

  9. 21 CFR 864.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Effective dates of requirement for premarket approval. 864.3 Section 864.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES General Provisions § 864.3 Effective...

  10. 21 CFR 892.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Effective dates of requirement for premarket approval. 892.3 Section 892.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES General Provisions § 892.3 Effective dates of...

  11. 49 CFR 393.11 - Lamps and reflective devices.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., meet the applicable requirements of 49 CFR 571.108 (FMVSS No. 108) in effect at the time of manufacture..., meet the requirements of subpart B of part 393 in effect at the time of manufacture. (2) Exceptions... devices and electrical equipment in effect at the time of manufacture. Trailers which are equipped with...

  12. Implementation of ionizing radiation environment requirements for Space Station

    NASA Technical Reports Server (NTRS)

    Boeder, Paul A.; Watts, John W.

    1993-01-01

    Proper functioning of Space Station hardware requires that the effects of high-energy ionizing particles from the natural environment and (possibly) from man-made sources be considered during design. At the Space Station orbit of 28.5-deg inclination and 330-440 km altitude, geomagnetically trapped protons and electrons contribute almost all of the dose, while galactic cosmic rays and anomalous cosmic rays may produce Single Event Upsets (SEUs), latchups, and burnouts of microelectronic devices. Implementing ionizing radiation environment requirements for Space Station has been a two part process, including the development of a description of the environment for imposing requirements on the design and the development of a control process for assessing how well the design addresses the effects of the ionizing radiation environment. We will review both the design requirements and the control process for addressing ionizing radiation effects on Space Station.

  13. 48 CFR 52.216-21 - Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Requirements. 52.216-21... Requirements. As prescribed in 16.506(d), insert the following clause: Requirements (OCT 1995) (a) This is a requirements contract for the supplies or services specified, and effective for the period stated, in the...

  14. 48 CFR 52.216-21 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Requirements. 52.216-21... Requirements. As prescribed in 16.506(d), insert the following clause: Requirements (OCT 1995) (a) This is a requirements contract for the supplies or services specified, and effective for the period stated, in the...

  15. 48 CFR 52.216-21 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Requirements. 52.216-21... Requirements. As prescribed in 16.506(d), insert the following clause: Requirements (OCT 1995) (a) This is a requirements contract for the supplies or services specified, and effective for the period stated, in the...

  16. 48 CFR 52.216-21 - Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Requirements. 52.216-21... Requirements. As prescribed in 16.506(d), insert the following clause: Requirements (OCT 1995) (a) This is a requirements contract for the supplies or services specified, and effective for the period stated, in the...

  17. 43 CFR 17.209 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Effect of State or local law or other requirements and effect of employment opportunities. 17.209 Section 17.209 Public Lands: Interior Office of the Secretary of the Interior NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OF THE DEPARTMENT OF THE INTERIOR Nondiscrimination on the Basis o...

  18. 45 CFR 84.10 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Effect of State or local law or other requirements and effect of employment opportunities. 84.10 Section 84.10 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE...

  19. Effect of commercial and military performance requirements for transport category aircraft on space shuttle booster design and operation

    NASA Technical Reports Server (NTRS)

    Bithell, R. A.; Pence, W. A., Jr.

    1972-01-01

    The effect of two sets of performance requirements, commercial and military, on the design and operation of the space shuttle booster is evaluated. Critical thrust levels are established according to both sets of operating rules for the takeoff, cruise, and go-around flight modes, and the effect on engine requirements determined. Both flyback and ferry operations are considered. The impact of landing rules on potential shuttle flyback and ferry bases is evaluated. Factors affecting reserves are discussed, including winds, temperature, and nonstandard flight operations. Finally, a recommended set of operating rules is proposed for both flyback and ferry operations that allows adequate performance capability and safety margins without compromising design requirements for either flight phase.

  20. Standards applicable to owners and operators of hazardous waste treatment, storage, and disposal facilities; liability coverage requirements--Environmental Protection Agency. Final rule and notice of extension of effective date.

    PubMed

    1982-07-13

    The effective date for qualifications of insurers providing liability insurance used to satisfy liability coverage requirements applicable to owners or operators of hazardous waste management facilities, as such requirements are included in 40 CFR Parts 264 and 265, is extended from July 15, 1982, to October 16, 1982. The effective date for the rest of the liability coverage requirements remains July 15, 1982. This extension is being provided to allow 6 months between the date of promulgation and the effective date for the insurer qualification provision, in accordance with Section 3010(b) of the Resource Conservation and Recovery Act of 1976, as amended. During the period between July 15 and October 16, 1982, owners or operators may use certificates of insurance or policy endorsements that do not certify to the qualifications of the insurer.

  1. OSHA safety requirements for hazardous chemicals in the workplace.

    PubMed

    Dohms, J

    1992-01-01

    This article outlines the Occupational Safety and Health Administration (OSHA) requirements set forth by the Hazard Communication Standard, which has been in effect for the healthcare industry since 1987. Administrators who have not taken concrete steps to address employee health and safety issues relating to hazardous chemicals are encouraged to do so to avoid the potential of large fines for cited violations. While some states administer their own occupational safety and health programs, they must adopt standards and enforce requirements that are at least as effective as federal requirements.

  2. Energy requirements of adult dogs: a meta-analysis.

    PubMed

    Bermingham, Emma N; Thomas, David G; Cave, Nicholas J; Morris, Penelope J; Butterwick, Richard F; German, Alexander J

    2014-01-01

    A meta-analysis was conducted to determine the maintenance energy requirements of adult dogs. Suitable publications were first identified, and then used to generate relationships amongst energy requirements, husbandry, activity level, methodology, sex, neuter status, dog size, and age in healthy adult dogs. Allometric equations for maintenance energy requirements were determined using log-log linear regression. So that the resulting equations could readily be compared with equations reported by the National Research Council, maintenance energy requirements in the current study were determined in kcal/kg(0.75) body weight (BW). Ultimately, the data of 70 treatment groups from 29 publications were used, and mean (± standard deviation) maintenance energy requirements were 142.8±55.3 kcal·kgBW(-0.75)·day(-1). The corresponding allometric equation was 81.5 kcal·kgBW(-0.9)·day(-1) (adjusted R2 = 0.64; 70 treatment groups). Type of husbandry had a significant effect on maintenance energy requirements (P<0.001): requirements were greatest in racing dogs, followed by working dogs and hunting dogs, whilst the energy requirements of pet dogs and kennel dogs were least. Maintenance energy requirements were less in neutered compared with sexually intact dogs (P<0.001), but there was no effect of sex. Further, reported activity level tended to effect the maintenance energy requirement of the dog (P = 0.09). This review suggests that estimating maintenance energy requirements based on BW alone may not be accurate, but that predictions that factor in husbandry, neuter status and, possibly, activity level might be superior. Additionally, more information on the nutrient requirements of older dogs, and those at the extremes of body size (i.e. giant and toy breeds) is needed.

  3. Energy Requirements of Adult Dogs: A Meta-Analysis

    PubMed Central

    Bermingham, Emma N.; Thomas, David G.; Cave, Nicholas J.; Morris, Penelope J.; Butterwick, Richard F.; German, Alexander J.

    2014-01-01

    A meta-analysis was conducted to determine the maintenance energy requirements of adult dogs. Suitable publications were first identified, and then used to generate relationships amongst energy requirements, husbandry, activity level, methodology, sex, neuter status, dog size, and age in healthy adult dogs. Allometric equations for maintenance energy requirements were determined using log-log linear regression. So that the resulting equations could readily be compared with equations reported by the National Research Council, maintenance energy requirements in the current study were determined in kcal/kg0.75 body weight (BW). Ultimately, the data of 70 treatment groups from 29 publications were used, and mean (± standard deviation) maintenance energy requirements were 142.8±55.3 kcal.kgBW−0.75.day−1. The corresponding allometric equation was 81.5 kcal.kgBW−0.93.day−1 (adjusted R2 = 0.64; 70 treatment groups). Type of husbandry had a significant effect on maintenance energy requirements (P<0.001): requirements were greatest in racing dogs, followed by working dogs and hunting dogs, whilst the energy requirements of pet dogs and kennel dogs were least. Maintenance energy requirements were less in neutered compared with sexually intact dogs (P<0.001), but there was no effect of sex. Further, reported activity level tended to effect the maintenance energy requirement of the dog (P = 0.09). This review suggests that estimating maintenance energy requirements based on BW alone may not be accurate, but that predictions that factor in husbandry, neuter status and, possibly, activity level might be superior. Additionally, more information on the nutrient requirements of older dogs, and those at the extremes of body size (i.e. giant and toy breeds) is needed. PMID:25313818

  4. 40 CFR 52.1528 - Control strategy: Carbon monoxide.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... effect through the year 2020, as required by the Clean Air Act. If the area records a violation of the... that the maintenance plan will remain in effect through the year 2020, as required by the Clean Air Act...

  5. 40 CFR 52.1528 - Control strategy: Carbon monoxide.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... effect through the year 2020, as required by the Clean Air Act. If the area records a violation of the... that the maintenance plan will remain in effect through the year 2020, as required by the Clean Air Act...

  6. Design for interaction between humans and intelligent systems during real-time fault management

    NASA Technical Reports Server (NTRS)

    Malin, Jane T.; Schreckenghost, Debra L.; Thronesbery, Carroll G.

    1992-01-01

    Initial results are reported to provide guidance and assistance for designers of intelligent systems and their human interfaces. The objective is to achieve more effective human-computer interaction (HCI) for real time fault management support systems. Studies of the development of intelligent fault management systems within NASA have resulted in a new perspective of the user. If the user is viewed as one of the subsystems in a heterogeneous, distributed system, system design becomes the design of a flexible architecture for accomplishing system tasks with both human and computer agents. HCI requirements and design should be distinguished from user interface (displays and controls) requirements and design. Effective HCI design for multi-agent systems requires explicit identification of activities and information that support coordination and communication between agents. The effects are characterized of HCI design on overall system design and approaches are identified to addressing HCI requirements in system design. The results include definition of (1) guidance based on information level requirements analysis of HCI, (2) high level requirements for a design methodology that integrates the HCI perspective into system design, and (3) requirements for embedding HCI design tools into intelligent system development environments.

  7. 76 FR 5537 - Electronic On-Board Recorders and Hours of Service Supporting Documents

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-01

    ...The Federal Motor Carrier Safety Administration (FMCSA) proposes to amend the Federal Motor Carrier Safety Regulations (FMCSRs) to require certain motor carriers operating commercial motor vehicles (CMVs) in interstate commerce to use electronic on-board recorders (EOBRs) to document their drivers' hours of service (HOS). Under this proposal, all motor carriers currently required to maintain Records of Duty Status (RODS) for HOS recordkeeping would be required to use EOBRs to systematically and effectively monitor their drivers' compliance with HOS requirements. Additionally, this proposal sets forth the supporting documents that all motor carriers currently required to use RODS would still be required to obtain and keep, as required by section 113(a) of the Hazardous Materials Transportation Authorization Act (HMTAA). It explains, however, that although motor carriers subject to the proposed EOBR requirements would still need to retain some supporting documents, they would be relieved of the requirements to retain supporting documents to verify driving time. FMCSA also proposes to require all motor carriers--both RODS and timecard users--to systematically monitor their drivers' compliance with HOS requirements. Motor carriers would be given 3 years after the effective date of the final rule to comply with these requirements.

  8. Effects of Differing Response-Force Requirements on Food-Maintained Responding in C57BL/6J Mice

    ERIC Educational Resources Information Center

    Zarcone, Troy J.; Chen, Rong; Fowler, Stephen C.

    2009-01-01

    The effect of force requirements on response effort was examined using inbred C57BL/6J mice trained to press a disk with their snout. Lateral peak forces greater than 2 g were defined as responses (i.e., all responses above the measurement threshold). Different, higher force requirements were used to define criterion responses (a subclass of all…

  9. The Effects of the 150-Credit-Hour Requirement for the Certified Public Accountant (CPA) Exam On the Career Intentions of Women and Minorities

    ERIC Educational Resources Information Center

    Bierstaker, James Lloyd; Howe, Martha A.; Seol, Inshik

    2005-01-01

    In most states, students who sit for the certified public accountant (CPA) examination are now required to have 150 credit hours of college education. In this article, the authors examined the effects of this requirement on the career intentions of women and minorities. The authors collected data from 600 accounting students and the results…

  10. Passing through Science: The Effects of Raising Graduation Requirements in Science on Course-Taking and Academic Achievement in Chicago. Research Report

    ERIC Educational Resources Information Center

    Montgomery, Nicholas; Allensworth, Elaine M.

    2010-01-01

    This report examines the effects of increasing science course-taking requirements in the Chicago Public Schools. CPS has been at the forefront of the national movement to require a college-preparatory curriculum for all high school students. In 1997, CPS mandated that all entering ninth-graders take a college-preparatory curriculum in high school,…

  11. The capability of satellite borne remote sensors to measure stratospheric trace constituents. Volume 2: Ozone and aerosol related missions

    NASA Technical Reports Server (NTRS)

    Keitz, E. L.

    1978-01-01

    Stratospheric trace constituent measurement requirements are separated into two somewhat overlapping areas. In the first area, it is assumed that the only problem of interest is ozone; its chemistry chain, environmental effects and measurement requirements. In like manner, in the second area it is assumed that the only problem of interest is stratospheric aerosols; their chemistry, effects and measurement requirements.

  12. 7 CFR 1486.507 - What is the effect of failing to make required contributions?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false What is the effect of failing to make required... MARKETS PROGRAM Reporting, Evaluation, and Compliance § 1486.507 What is the effect of failing to make... percentage basis, the original ratio of private contributions to the authorized EMP funding level. ...

  13. 7 CFR 1486.507 - What is the effect of failing to make required contributions?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false What is the effect of failing to make required... MARKETS PROGRAM Reporting, Evaluation, and Compliance § 1486.507 What is the effect of failing to make... percentage basis, the original ratio of private contributions to the authorized EMP funding level. ...

  14. Effectiveness of a Required Health-Related Fitness Course on Dietary Behaviors among Community College Students

    ERIC Educational Resources Information Center

    Evans, Melissa S.; Massey-Stokes, Marilyn; Denson, Kathleen

    2018-01-01

    Purpose: The purpose of this mixed-methods study was to: (a) evaluate the effectiveness of a required Health-Related Fitness (HRF) course in changing dietary behaviors among community college (CC) students, and (b) explore student perceptions about the effectiveness of HRF curriculum activities in changing behaviors. Methods: Pre- and…

  15. "Do I Have to Take This Class?" Nontraditional Students' Attitudes toward and Perceptions of a Required Effective Learning Course

    ERIC Educational Resources Information Center

    Gordon, Evelyn J.

    2014-01-01

    This study involves nontraditional students attending a community college in west Texas. The purpose of this study was to report initial attitudes of nontraditional students required to enroll in an Effective Learning/Student Success course. Participants included four nontraditional students from the researchers' Effective Learning/Student Success…

  16. 7 CFR 15b.9 - Effect of State or local law or other requirements, and effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Effect of State or local law or other requirements, and effect of employment opportunities. 15b.9 Section 15b.9 Agriculture Office of the Secretary of Agriculture NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 15b.9 Effec...

  17. Income Eligibility Thresholds, Premium Contributions, and Children's Coverage Outcomes: A Study of CHIP Expansions

    PubMed Central

    Gresenz, Carole Roan; Edgington, Sarah E; Laugesen, Miriam J; Escarce, José J

    2013-01-01

    Objective To understand the effects of Children's Health Insurance Program (CHIP) income eligibility thresholds and premium contribution requirements on health insurance coverage outcomes among children. Data Sources 2002–2009 Annual Social and Economic Supplements of the Current Population Survey linked to data from multiple secondary data sources. Study Design We use a selection correction model to simultaneously estimate program eligibility and coverage outcomes conditional upon eligibility. We simulate the effects of three premium schedules representing a range of generosity levels and the effects of income eligibility thresholds ranging from 200 to 400 percent of the federal poverty line. Principal Findings Premium contribution requirements decrease enrollment in public coverage and increase enrollment in private coverage, with larger effects for greater contribution levels. Our simulation results suggest minimal changes in coverage outcomes from eligibility expansions to higher income families under premium schedules that require more than a modest contribution (medium or high schedules). Conclusions Our simulation results are useful counterpoints to previous research that has estimated the average effect of program expansions as they were implemented without disentangling the effects of premiums or other program features. The sensitivity to premiums observed suggests that although contribution requirements may be effective in reducing crowd-out, they also have the potential, depending on the level of contribution required, to nullify the effects of CHIP expansions entirely. The persistence of uninsurance among children under the range of simulated scenarios points to the importance of Affordable Care Act provisions designed to make the process of obtaining coverage transparent and navigable. PMID:23398477

  18. Income eligibility thresholds, premium contributions, and children's coverage outcomes: a study of CHIP expansions.

    PubMed

    Gresenz, Carole Roan; Edgington, Sarah E; Laugesen, Miriam J; Escarce, José J

    2013-04-01

    To understand the effects of Children's Health Insurance Program (CHIP) income eligibility thresholds and premium contribution requirements on health insurance coverage outcomes among children. 2002-2009 Annual Social and Economic Supplements of the Current Population Survey linked to data from multiple secondary data sources. We use a selection correction model to simultaneously estimate program eligibility and coverage outcomes conditional upon eligibility. We simulate the effects of three premium schedules representing a range of generosity levels and the effects of income eligibility thresholds ranging from 200 to 400 percent of the federal poverty line. Premium contribution requirements decrease enrollment in public coverage and increase enrollment in private coverage, with larger effects for greater contribution levels. Our simulation results suggest minimal changes in coverage outcomes from eligibility expansions to higher income families under premium schedules that require more than a modest contribution (medium or high schedules). Our simulation results are useful counterpoints to previous research that has estimated the average effect of program expansions as they were implemented without disentangling the effects of premiums or other program features. The sensitivity to premiums observed suggests that although contribution requirements may be effective in reducing crowd-out, they also have the potential, depending on the level of contribution required, to nullify the effects of CHIP expansions entirely. The persistence of uninsurance among children under the range of simulated scenarios points to the importance of Affordable Care Act provisions designed to make the process of obtaining coverage transparent and navigable. © Health Research and Educational Trust.

  19. The Effect of Lift on Entry Corridor Depth and Guidance Requirements for the Return Lunar Flight

    NASA Technical Reports Server (NTRS)

    Wong, Thomas J.; Slye, Robert E.

    1961-01-01

    Corridors for manned vehicles are defined consistent with requirements for avoiding radiation exposure and for limiting values of peak deceleration. Use of lift increases the depth of the entry corridor. Mid-course guidance requirements appear to be critical only for the flight-path angle. Increasing the energy of the transport orbit increases the required guidance accuracy for the flight-path angle. Corrective thrust applied essentially parallel to the local horizontal produces the maximum change in perigee altitude for a given increment of velocity. Energy required to effect a given change in perigee altitude varies inversely with range measured from the center of the earth.

  20. 49 CFR 565.25 - Content requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 6 2012-10-01 2012-10-01 false Content requirements. 565.25 Section 565.25 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE IDENTIFICATION NUMBER (VIN) REQUIREMENTS Alternative VIN Requirements In Effect for Limited Period...

  1. 49 CFR 565.25 - Content requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 6 2014-10-01 2014-10-01 false Content requirements. 565.25 Section 565.25 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE IDENTIFICATION NUMBER (VIN) REQUIREMENTS Alternative VIN Requirements In Effect for Limited Period...

  2. 49 CFR 565.25 - Content requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 6 2013-10-01 2013-10-01 false Content requirements. 565.25 Section 565.25 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE IDENTIFICATION NUMBER (VIN) REQUIREMENTS Alternative VIN Requirements In Effect for Limited Period...

  3. 36 CFR 801.7 - Information requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Information requirements. 801... HISTORIC PRESERVATION REQUIREMENTS OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.7 Information requirements. (a) Information To Be Retained by Applicants Determining No Effect. (1) Recommended Documentation...

  4. 45 CFR 164.316 - Policies and procedures and documentation requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... when it last was in effect, whichever is later. (ii) Availability (Required). Make documentation.... (iii) Updates (Required). Review documentation periodically, and update as needed, in response to...

  5. 16 CFR 1021.5 - Categories of CPSC actions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... effects and therefore, normally require environmental assessments but not necessarily environmental impact... an environmental assessment nor an environmental impact statement is required. (These categories are... environmental effects. Therefore, there are no actions for which an environmental impact statement is normally...

  6. 16 CFR 1021.5 - Categories of CPSC actions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... effects and therefore, normally require environmental assessments but not necessarily environmental impact... an environmental assessment nor an environmental impact statement is required. (These categories are... environmental effects. Therefore, there are no actions for which an environmental impact statement is normally...

  7. 16 CFR 1021.5 - Categories of CPSC actions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... effects and therefore, normally require environmental assessments but not necessarily environmental impact... an environmental assessment nor an environmental impact statement is required. (These categories are... environmental effects. Therefore, there are no actions for which an environmental impact statement is normally...

  8. 16 CFR 1021.5 - Categories of CPSC actions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... effects and therefore, normally require environmental assessments but not necessarily environmental impact... an environmental assessment nor an environmental impact statement is required. (These categories are... environmental effects. Therefore, there are no actions for which an environmental impact statement is normally...

  9. 7 CFR 1944.683 - Reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... analyze the effectiveness of the program. As part of the grantee's preapplication submission, as required..., including its method of evaluation to determine its effectiveness. Accordingly, the report must include, but...

  10. Attentional load inhibits vection.

    PubMed

    Seno, Takeharu; Ito, Hiroyuki; Sunaga, Shoji

    2011-07-01

    In this study, we examined the effects of cognitive task performance on the induction of vection. We hypothesized that, if vection requires attentional resources, performing cognitive tasks requiring attention should inhibit or weaken it. Experiment 1 tested the effects on vection of simultaneously performing a rapid serial visual presentation (RSVP) task. The results revealed that the RSVP task affected the subjective strength of vection. Experiment 2 tested the effects of a multiple-object-tracking (MOT) task on vection. Simultaneous performance of the MOT task decreased the duration and subjective strength of vection. Taken together, these findings suggest that vection induction requires attentional resources.

  11. 32 CFR Enclosure 1 - Requirements for Environmental Considerations-Global Commons

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Requirements for Environmental Considerations... ENVIRONMENT ENVIRONMENTAL EFFECTS ABROAD OF MAJOR DEPARTMENT OF DEFENSE ACTIONS Information requirements. Pt. 187, Encl. 1 Enclosure 1—Requirements for Environmental Considerations—Global Commons A. General. This...

  12. 32 CFR Enclosure 1 - Requirements for Environmental Considerations-Global Commons

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Requirements for Environmental Considerations... ENVIRONMENT ENVIRONMENTAL EFFECTS ABROAD OF MAJOR DEPARTMENT OF DEFENSE ACTIONS Information requirements. Pt. 187, Encl. 1 Enclosure 1—Requirements for Environmental Considerations—Global Commons A. General. This...

  13. 49 CFR 565.23 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE IDENTIFICATION NUMBER (VIN) REQUIREMENTS Alternative VIN Requirements In Effect for Limited Period § 565.23 General requirements. (a) Each vehicle manufactured in one stage shall have a VIN that is assigned by the manufacturer. Each vehicle manufactured in more than one...

  14. 49 CFR 565.23 - General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE IDENTIFICATION NUMBER (VIN) REQUIREMENTS Alternative VIN Requirements In Effect for Limited Period § 565.23 General requirements. (a) Each vehicle manufactured in one stage shall have a VIN that is assigned by the manufacturer. Each vehicle manufactured in more than one...

  15. 49 CFR 565.23 - General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE IDENTIFICATION NUMBER (VIN) REQUIREMENTS Alternative VIN Requirements In Effect for Limited Period § 565.23 General requirements. (a) Each vehicle manufactured in one stage shall have a VIN that is assigned by the manufacturer. Each vehicle manufactured in more than one...

  16. 49 CFR 565.23 - General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE IDENTIFICATION NUMBER (VIN) REQUIREMENTS Alternative VIN Requirements In Effect for Limited Period § 565.23 General requirements. (a) Each vehicle manufactured in one stage shall have a VIN that is assigned by the manufacturer. Each vehicle manufactured in more than one...

  17. 49 CFR 565.23 - General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE IDENTIFICATION NUMBER (VIN) REQUIREMENTS Alternative VIN Requirements In Effect for Limited Period § 565.23 General requirements. (a) Each vehicle manufactured in one stage shall have a VIN that is assigned by the manufacturer. Each vehicle manufactured in more than one...

  18. Formalizing Space Shuttle Software Requirements

    NASA Technical Reports Server (NTRS)

    Crow, Judith; DiVito, Ben L.

    1996-01-01

    This paper describes two case studies in which requirements for new flight-software subsystems on NASA's Space Shuttle were analyzed, one using standard formal specification techniques, the other using state exploration. These applications serve to illustrate three main theses: (1) formal methods can complement conventional requirements analysis processes effectively, (2) formal methods confer benefits regardless of how extensively they are adopted and applied, and (3) formal methods are most effective when they are judiciously tailored to the application.

  19. 26 CFR 1.7519-1T - Required payments for entities electing not to have required year (temporary).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... section 444 in effect (an “applicable election year”). (2) Returns and required payments. For each.... (3) Required payment. The term “required payment” means, with respect to any applicable election year... provided in paragraph (b)(1)(ii) of this section, the term “applicable percentage” means the percentage...

  20. "With Some Families, Nothing Goes Right."

    ERIC Educational Resources Information Center

    Exceptional Parent, 1986

    1986-01-01

    A case history describes the effects on a family of a child whose cleft palate required frequent medical attention. Adjustments required by a completion of surgery are noted to have unsettling effects on the 10-year-old brother and his mother and father. (CL)

  1. Biomedical and Human Factors Requirements for a Manned Earth-Orbiting Station

    NASA Technical Reports Server (NTRS)

    Reynolds, J. B.

    1963-01-01

    The study reported here has presented a measurement data pool for the determination of biomedical and behavioral effects of long-term exposure to weightlessness. This includes measures, techniques, equipment, and requirements in terms of weight, power, volume, time, crew activities, subsystem interfaces and experimental programs and designs, and confidence ratings for their effectiveness for determining weightlessness effects.

  2. 45 CFR 400.77 - Effect of quitting employment or failing or refusing to participate in required services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Effect of quitting employment or failing or... Employment General Requirements § 400.77 Effect of quitting employment or failing or refusing to participate... quit employment or have refused to accept an offer of employment determined to be appropriate by the...

  3. Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups

    PubMed Central

    da Costa, Kerry-Ann; Corbin, Karen D.; Niculescu, Mihai D.; Galanko, Joseph A.; Zeisel, Steven H.

    2014-01-01

    Effect alleles (alleles with a polymorphism that is associated with the effect being measured) in a small number of single-nucleotide polymorphisms (SNPs) are known to influence the dietary requirement for choline. In this study, we examined a much larger number of SNPs (n=200) in 10 genes related to choline metabolism for associations with development of organ dysfunction (liver or muscle) when 79 humans were fed a low-choline diet. We confirmed that effect alleles in SNPs such as the C allele of PEMT rs12325817 increase the risk of developing organ dysfunction in women when they consume a diet low in choline, and we identified novel effect alleles, such as the C allele of CHKA SNP rs7928739, that alter dietary choline requirements. When fed a low-choline diet, some people presented with muscle damage rather than liver damage; several effect alleles in SLC44A1 (rs7873937, G allele; rs2771040, G; rs6479313, G; rs16924529, A; and rs3199966, C) and one in CHKB (rs1557502, A) were more common in these individuals. This suggests that pathways related to choline metabolism are more important for normal muscle function than previously thought. In European, Mexican, and Asian Americans, and in individuals of African descent, we examined the prevalence of the effect alleles in SNPs that alter choline requirement and found that they are differentially distributed among people of different ethnic and racial backgrounds. Overall, our study has identified novel genetic variants that modulate choline requirements and suggests that the dietary requirement for choline may be different across racial and ethnic groups.—Da Costa, K.-A., Corbin, K. D., Niculescu, M. D., Galanko, J. A., Zeisel, S. H. Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups. PMID:24671709

  4. High School Physical Education Requirements and Youth Body Weight: New Evidence from the YRBS.

    PubMed

    Sabia, Joseph J; Nguyen, Thanh Tam; Rosenberg, Oren

    2017-10-01

    Previous research has found that high school physical education (PE) requirements are largely ineffective at reducing youth body weight. However, these studies were forced to rely on cross-state variation in PE requirements to identify their impacts, raising concerns that estimated policy effects may be confounded by state-level unobservables. Using data from the State and National Youth Risk Behavior Surveys and exploiting recent changes in state high school PE laws, we re-examine the effect of PE requirements on body weight. Our estimates show that a one-semester increase in PE requirements is associated with a 10 to 13% increase in minutes per week spent physically active in PE classes, but with no change in net vigorous exercise and little change in youth body weight. We conclude that substitution of in-school for outside-of-school physical activity and small resultant net energy expenditures can explain the absence of body weight effects. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  5. Does adding low doses of oral naltrexone to morphine alter the subsequent opioid requirements and side effects in trauma patients?

    PubMed

    Farahmand, Shervin; Ahmadi, Omid; Dehpour, Ahmadreza; Khashayar, Patricia

    2012-01-01

    The present study aims to assess the influence of ultra-low doses of opioid antagonists on the analgesic properties of opioids and their side effects. In the present randomized, double-blind controlled trial, the influence of the combination of ultra-low-dose naltrexone and morphine on the total opioid requirement and the frequency of the subsequent side effects was compared with that of morphine alone (added with placebo) in patients with trauma in the upper or lower extremities. Although the morphine and naltrexone group required 0.04 mg more opioids during the study period, there was no significant difference between the opioid requirements of the 2 groups. Nausea was less frequently reported in patients receiving morphine and naltrexone. The combination of ultra-low-dose naltrexone and morphine in extremity trauma does not affect the opioid requirements; it, however, lowers the risk of nausea. Copyright © 2012 Elsevier Inc. All rights reserved.

  6. Radiation exposure levels within timber industries in Calabar, Nigeria

    PubMed Central

    Inyang, S. O.; Inyang, I. S.; Egbe, N. O.

    2009-01-01

    The UNSCEAR (2000) observed that there could be some exposure at work which would require regulatory control but is not really considered. This study was, therefore, set up to evaluate the effective dose in timber industries in Calabar, Nigeria to determine if the evaluated dose levels could lead to any radiological health effect in the workers, and also determine if the industries require regulatory control. The gamma ray exposure at four timber industries measured using an exposure meter were converted to effective dose and compared with the public and occupational values. The evaluated effective dose values in the timber industries were below public and occupational exposure limits and may not necessarily result in any radiological health hazard. Therefore, they may not require regulatory control. PMID:20098544

  7. Assessing potency of high- and low-preference reinforcers with respect to response rate and response patterns.

    PubMed

    Penrod, Becky; Wallace, Michele D; Dyer, Edwin J

    2008-01-01

    Previous research has suggested that the availability of high-preference stimuli may override the reinforcing efficacy of concurrently available low-preference stimuli under relatively low schedule requirements (e.g., fixed-ratio 1 schedule). It is unknown if similar effects would be obtained under higher schedule requirements. Thus, the current study compared high-preference and low-preference reinforcers under progressively increasing schedule requirements. Results for 3 of the 4 participants indicated that high-preference stimuli maintained responding under higher schedule requirements relative to low-preference stimuli. For 1 participant, high-preference and low-preference stimuli were demonstrated to be equally effective reinforcers under increasing schedule requirements. Implications with respect to rate of performance and response patterns are discussed.

  8. 21 CFR 814.82 - Postapproval requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... periodic reporting on the safety, effectiveness, and reliability of the device for its intended use. FDA... a device and in the advertising of any restricted device of warnings, hazards, or precautions... extent required for the medical welfare of the individual, to determine the safety or effectiveness of...

  9. Vocabulary Levels and Size of Malaysian Undergraduates

    ERIC Educational Resources Information Center

    Harji, Madhubala Bava; Balakrishnan, Kavitha; Bhar, Sareen Kaur; Letchumanan, Krishnaveni

    2015-01-01

    Vocabulary is a fundamental requirement of language acquisition, and its competence enables independent reading and effective language acquisition. Effective language use requires adequate level of vocabulary knowledge; therefore, efforts must be made to identify students' vocabulary base for greater efficiency and competency in the language.…

  10. Effect-site concentration of remifentanil required to blunt haemodynamic responses during tracheal intubation: A randomized comparison between single- and double-lumen tubes.

    PubMed

    Kim, Tae Kyong; Hong, Deok Man; Lee, Seo Hee; Paik, Hyesun; Min, Se Hee; Seo, Jeong-Hwa; Jung, Chul-Woo; Bahk, Jae-Hyon

    2018-01-01

    Objective To investigate the effect-site concentration of remifentanil required to blunt haemodynamic responses during tracheal intubation with a single-lumen tube (SLT) or a double-lumen tube (DLT). Methods Patients scheduled for thoracic surgery requiring one-lung ventilation were randomly allocated to either the SLT or DLT group. All patients received a target-controlled infusion of propofol and a predetermined concentration of remifentanil. Haemodynamic parameters during intubation were recorded. The effect-site concentration of remifentanil was determined using a delayed up-and-down sequential allocation method. Results A total of 92 patients were enrolled in the study. The effective effect-site concentrations of remifentanil required to blunt haemodynamic responses in 50% of patients (EC 50 ) estimated by isotonic regression with bootstrapping was higher in the DLT than the SLT group (8.5 ng/ml [95% confidence interval (CI) 8.0-9.5 ng/ml] versus 6.5 ng/ml [95% CI 5.6-6.7 ng/ml], respectively). Similarly, the effective effect-site concentrations of remifentanil in 95% of patients in the DLT group was higher than the SLT group (9.9 ng/ml [95% CI 9.8-10.0 ng/ml] versus 7.0 ng/ml [95% CI 6.9-7.0 ng/ml], respectively). Conclusions This study demonstrated that a DLT requires a 30% higher EC 50 of remifentanil than does an SLT to blunt haemodynamic responses during tracheal intubation when combined with a target-controlled infusion of propofol. Trial registration Clinicaltrials.gov identifier: NCT01542099.

  11. 42 CFR 422.516 - Validation of Part C reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Contracts for Medicare Advantage Organizations § 422.516 Validation of Part C reporting requirements. (a) Required information. Each MA organization must have an effective procedure to develop, compile, evaluate... demonstrating that the MA organization has a fiscally sound operation. (6) Other matters that CMS may require...

  12. 42 CFR 422.516 - Validation of Part C reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Contracts for Medicare Advantage Organizations § 422.516 Validation of Part C reporting requirements. (a) Required information. Each MA organization must have an effective procedure to develop, compile, evaluate... demonstrating that the MA organization has a fiscally sound operation. (6) Other matters that CMS may require...

  13. Maneuver Recovery Analysis for the Magnetospheric Multiscale Mission

    NASA Technical Reports Server (NTRS)

    Gramling, Cheryl; Carpenter, Russell; Volle, Michael; Lee, Taesul; Long, Anne

    2007-01-01

    The use of spacecraft formations creates new and more demanding requirements for orbit determination accuracy. In addition to absolute navigation requirements, there are typically relative navigation requirements that are based on the size or shape of the formation. The difficulty in meeting these requirements is related to the relative dynamics of the spacecraft orbits and the frequency of the formation maintenance maneuvers. This paper examines the effects of bi-weekly formation maintenance maneuvers on the absolute and relative orbit determination accuracy for the four-spacecraft Magnetospheric Multiscale (MMS) formation. Results are presented from high fidelity simulations that include the effects of realistic orbit determination errors in the maneuver planning process. Solutions are determined using a high accuracy extended Kalman filter designed for onboard navigation. Three different solutions are examined, considering the effects of process noise and measurement rate on the solutions.

  14. Effects of Requiring Physical Fitness in a Lecture-Based College Course: Students' Attitudes toward Physical Activity

    ERIC Educational Resources Information Center

    Esslinger, Keri A.; Grimes, Amanda R.; Pyle, Elizabeth

    2016-01-01

    In this study, we investigated students' attitudes toward physical activity (PA) when including a required PA component in a university-required personal wellness class. The study included (a) an experimental group of students enrolled in a personal wellness course in which there was a required PA requirement and (b) a control group of students…

  15. Effects of iodine deficiency in pregnancy.

    PubMed

    Pearce, Elizabeth N

    2012-06-01

    Dietary iodine requirements are increased in pregnancy due to increased thyroid hormone production, increased renal iodine losses, and fetal iodine requirements. Adverse effects of iodine deficiency in pregnancy include maternal and fetal goiter, cretinism, intellectual impairments, neonatal hypothyroidism, and increased pregnancy loss and infant. Dietary iodine requirements remain increased in lactation due to the concentration of iodine in breast milk. Iodine deficiency remains a significant global public health problem. Excess iodine ingestion in pregnancy, while a relatively uncommon problem, may also have adverse fetal effects. However, the safe upper limit for chronic iodine ingestion in pregnancy and lactation is not currently well defined. Copyright © 2012 Elsevier GmbH. All rights reserved.

  16. Defense Science Board Task Force on SEA BASING

    DTIC Science & Technology

    2003-08-01

    to: Consider the operational requirements, the assets required, the role(s) of new technologies, and the effects of “jointness” Examine the...improve effectiveness , efficiency or economy? Are there other doctrine, organizational, training, materiel, leadership, personnel or facilities aspects...sea of all four Services In effect , sea basing must become a truly joint concept with capabilities that allow for the projection of the full

  17. 76 FR 50663 - Effective Date of Requirement for Premarket Approval for Three Class III Preamendments Devices

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-16

    ... completion of a PDP is not filed by the latter of the two dates, and no IDE is in effect, the device is... availability of a preamendments class III devices strategy document. The strategy document set forth FDA's... approved PMA or a declared completed PDP is required to be in effect for any such devices on or before 180...

  18. Hydrologic considerations for estimation of storage-capacity requirements of impounding and side-channel reservoirs for water supply in Ohio

    USGS Publications Warehouse

    Koltun, G.F.

    2001-01-01

    This report provides data and methods to aid in the hydrologic design or evaluation of impounding reservoirs and side-channel reservoirs used for water supply in Ohio. Data from 117 streamflow-gaging stations throughout Ohio were analyzed by means of nonsequential-mass-curve-analysis techniques to develop relations between storage requirements, water demand, duration, and frequency. Information also is provided on minimum runoff for selected durations and frequencies. Systematic record lengths for the streamflow-gaging stations ranged from about 10 to 75 years; however, in many cases, additional streamflow record was synthesized. For impounding reservoirs, families of curves are provided to facilitate the estimation of storage requirements as a function of demand and the ratio of the 7-day, 2-year low flow to the mean annual flow. Information is provided with which to evaluate separately the effects of evaporation on storage requirements. Comparisons of storage requirements for impounding reservoirs determined by nonsequential-mass-curve-analysis techniques with storage requirements determined by annual-mass-curve techniques that employ probability routing to account for carryover-storage requirements indicate that large differences in computed required storages can result from the two methods, particularly for conditions where demand cannot be met from within-year storage. For side-channel reservoirs, tables of demand-storage-frequency information are provided for a primary pump relation consisting of one variable-speed pump with a pumping capacity that ranges from 0.1 to 20 times demand. Tables of adjustment ratios are provided to facilitate determination of storage requirements for 19 other pump sets consisting of assorted combinations of fixed-speed pumps or variable-speed pumps with aggregate pumping capacities smaller than or equal to the primary pump relation. The effects of evaporation on side-channel reservoir storage requirements are incorporated into the storage-requirement estimates. The effects of an instream-flow requirement equal to the 80-percent-duration flow are also incorporated into the storage-requirement estimates.

  19. 33 CFR 154.1130 - Requirements for prepositioned response equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Additional Response Plan Requirements for a Trans-Alaska Pipeline Authorization Act (TAPAA) Facility...: (a) On-water recovery equipment with a minimum effective daily recovery rate of 30,000 barrels... of a discharge. (c) On-water recovery equipment with a minimum effective daily recovery rate of 40...

  20. 33 CFR 154.1130 - Requirements for prepositioned response equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Additional Response Plan Requirements for a Trans-Alaska Pipeline Authorization Act (TAPAA) Facility...: (a) On-water recovery equipment with a minimum effective daily recovery rate of 30,000 barrels... of a discharge. (c) On-water recovery equipment with a minimum effective daily recovery rate of 40...

  1. 33 CFR 154.1130 - Requirements for prepositioned response equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Additional Response Plan Requirements for a Trans-Alaska Pipeline Authorization Act (TAPAA) Facility...: (a) On-water recovery equipment with a minimum effective daily recovery rate of 30,000 barrels... of a discharge. (c) On-water recovery equipment with a minimum effective daily recovery rate of 40...

  2. 33 CFR 154.1130 - Requirements for prepositioned response equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Additional Response Plan Requirements for a Trans-Alaska Pipeline Authorization Act (TAPAA) Facility...: (a) On-water recovery equipment with a minimum effective daily recovery rate of 30,000 barrels... of a discharge. (c) On-water recovery equipment with a minimum effective daily recovery rate of 40...

  3. A Guide to Effective School Leadership Theories

    ERIC Educational Resources Information Center

    Lynch, Matthew

    2012-01-01

    Educational administrators know that leadership requires hundreds of judgments each day that require a sensitivity and understanding of various leadership strategies. Bridging the gap between the academic and practical world, "A Guide to Effective School Leadership Theories" provides an exploration of ten dominant leadership strategies to give…

  4. U.S. Field Artillery after World War I: Modernizing the Force While Downsizing

    DTIC Science & Technology

    2014-06-13

    weapons, and tactics. It convened several boards to assess the requirements for an effective field artillery force, studying the materiel and......weapons, and tactics. It convened several boards to assess the requirements for an effective field artillery force, studying the materiel and

  5. Proposed Rule for Control of Air Pollution From New Motor Vehicles: Proposed Heavy-Duty Engine and Vehicle Standards and Highway Diesel Fuel Sulfur Control Requirements

    EPA Pesticide Factsheets

    Rule summary, CFR citations and additional resources concerning proposed new emission standards that will begin to take effect in 2007 and corresponding diesel fuel requirements that take effect in 2006.

  6. Reliability program requirements for aeronautical and space system contractors

    NASA Technical Reports Server (NTRS)

    1987-01-01

    General reliability program requirements for NASA contracts involving the design, development, fabrication, test, and/or use of aeronautical and space systems including critical ground support equipment are prescribed. The reliability program requirements require (1) thorough planning and effective management of the reliability effort; (2) definition of the major reliability tasks and their place as an integral part of the design and development process; (3) planning and evaluating the reliability of the system and its elements (including effects of software interfaces) through a program of analysis, review, and test; and (4) timely status indication by formal documentation and other reporting to facilitate control of the reliability program.

  7. 77 FR 1969 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-12

    ... Numerical Thresholds With Percentage Thresholds for the Investor Tiers' Volume Requirements January 6, 2012... replace numerical thresholds with percentage thresholds for the Investor Tiers' volume requirements. The...: Replacing Numerical Thresholds With Percentage Thresholds Effective June 1, 2011, NYSE Arca introduced two...

  8. Effects of Two Listening Strategies for Melodic Dictation

    ERIC Educational Resources Information Center

    Buonviri, Nathan O.

    2017-01-01

    The purpose of this research was to examine effects of two listening strategies on melodic dictation scores. Fifty-four undergraduate music majors completed short tonal melodic dictations in a within-subjects design with three conditions: (a) no specified strategy in the instructions, (b) required listening before writing, and (c) required writing…

  9. 40 CFR 63.312 - Existing regulations and requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... National Emission Standards for Coke Oven Batteries § 63.312 Existing regulations and requirements. (a) The..., topside port lids, coke oven doors, and charging operations in effect on September 15, 1992, or which have... method of monitoring in effect on September 15, 1992, and that ensures coke oven emission reductions...

  10. 40 CFR 63.312 - Existing regulations and requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... National Emission Standards for Coke Oven Batteries § 63.312 Existing regulations and requirements. (a) The..., topside port lids, coke oven doors, and charging operations in effect on September 15, 1992, or which have... method of monitoring in effect on September 15, 1992, and that ensures coke oven emission reductions...

  11. 40 CFR 63.312 - Existing regulations and requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... National Emission Standards for Coke Oven Batteries § 63.312 Existing regulations and requirements. (a) The..., topside port lids, coke oven doors, and charging operations in effect on September 15, 1992, or which have... method of monitoring in effect on September 15, 1992, and that ensures coke oven emission reductions...

  12. 40 CFR 63.312 - Existing regulations and requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... National Emission Standards for Coke Oven Batteries § 63.312 Existing regulations and requirements. (a) The..., topside port lids, coke oven doors, and charging operations in effect on September 15, 1992, or which have... method of monitoring in effect on September 15, 1992, and that ensures coke oven emission reductions...

  13. 40 CFR 63.312 - Existing regulations and requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... National Emission Standards for Coke Oven Batteries § 63.312 Existing regulations and requirements. (a) The..., topside port lids, coke oven doors, and charging operations in effect on September 15, 1992, or which have... method of monitoring in effect on September 15, 1992, and that ensures coke oven emission reductions...

  14. 21 CFR 862.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Effective dates of requirement for premarket approval. 862.3 Section 862.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES General Provisions...

  15. 78 FR 17747 - Agency Information Collection Activities: Request for Comments for a New Information Collection.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... define the types of analyses to be used to evaluate benefits, cost-effectiveness and feasibility...: Feasibility of Element-Level Bridge Inspection for Non- National Highway System Bridges. Background: The... a requirement for a study on the benefits, cost-effectiveness, and feasibility of requiring element...

  16. 40 CFR 725.67 - Applications to exempt new microorganisms from this part.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., small business, and technological innovation. (3) Specific requirements. In addition to the requirements... effect on the national economy, small business, technological innovation, the environment, and public... potential for adverse effects on health or the environment; (C) A history of safe commercial use for the...

  17. 40 CFR 725.67 - Applications to exempt new microorganisms from this part.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., small business, and technological innovation. (3) Specific requirements. In addition to the requirements... effect on the national economy, small business, technological innovation, the environment, and public... potential for adverse effects on health or the environment; (C) A history of safe commercial use for the...

  18. 40 CFR 725.67 - Applications to exempt new microorganisms from this part.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., small business, and technological innovation. (3) Specific requirements. In addition to the requirements... effect on the national economy, small business, technological innovation, the environment, and public... potential for adverse effects on health or the environment; (C) A history of safe commercial use for the...

  19. 5 CFR 315.201 - Service requirement for career tenure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... appointment under § 213.3202(b) of this chapter (the former Student Career Experience Program) as in effect immediately before the effective date of the regulations removing that paragraph, provided the student's... of his or her eligibility; (vii) Breaks incident to volunteer service or training required after...

  20. 5 CFR 315.201 - Service requirement for career tenure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... appointment under § 213.3202(b) of this chapter (the former Student Career Experience Program) as in effect immediately before the effective date of the regulations removing that paragraph, provided the student's... of his or her eligibility; (vii) Breaks incident to volunteer service or training required after...

  1. 40 CFR 98.66 - Data reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... emissions from anode effects in all prebake and all Sderberg electolysis cells combined. (2) Anode effect... overvoltage). (e) The following CO2-specific information for prebake cells: (1) Annual anode consumption. (2... addition to the information required by § 98.3(c), you must report the following information at the...

  2. 48 CFR 301.603-73 - Additional HHS training requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... electives for the purpose of satisfying FAC-C requirements or as continuous learning for maintenance of FAC-C or SAC certifications. (a) Earned value management training. Effective January 1, 2010, all... each be 8 hours or more in length. (b) Performance based acquisition training. Effective January 1...

  3. 48 CFR 301.603-73 - Additional HHS training requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... electives for the purpose of satisfying FAC-C requirements or as continuous learning for maintenance of FAC-C or SAC certifications. (a) Earned value management training. Effective January 1, 2010, all... each be 8 hours or more in length. (b) Performance based acquisition training. Effective January 1...

  4. 48 CFR 301.603-73 - Additional HHS training requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... electives for the purpose of satisfying FAC-C requirements or as continuous learning for maintenance of FAC-C or SAC certifications. (a) Earned value management training. Effective January 1, 2010, all... each be 8 hours or more in length. (b) Performance based acquisition training. Effective January 1...

  5. 48 CFR 301.603-73 - Additional HHS training requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... electives for the purpose of satisfying FAC-C requirements or as continuous learning for maintenance of FAC-C or SAC certifications. (a) Earned value management training. Effective January 1, 2010, all... each be 8 hours or more in length. (b) Performance based acquisition training. Effective January 1...

  6. 76 FR 69299 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    .... 80a-1 et seq.) (the ``Act'') is entitled ``Exemption of certain purchase or sale transactions between... transactions effected in reliance on the rule. The rule requires the fund's board of directors to establish... required to determine, at least on a quarterly basis, that all affiliated transactions effected during the...

  7. 16 CFR 305.23 - Effect on other law.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... DISCLOSURES REGARDING ENERGY CONSUMPTION AND WATER USE OF CERTAIN HOME APPLIANCES AND OTHER PRODUCTS REQUIRED UNDER THE ENERGY POLICY AND CONSERVATION ACT (âAPPLIANCE LABELING RULEâ) Effect of This Part § 305.23... product of information with respect to energy consumption, other than the information required to be...

  8. 16 CFR 305.23 - Effect on other law.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... DISCLOSURES REGARDING ENERGY CONSUMPTION AND WATER USE OF CERTAIN HOME APPLIANCES AND OTHER PRODUCTS REQUIRED UNDER THE ENERGY POLICY AND CONSERVATION ACT (âAPPLIANCE LABELING RULEâ) Effect of This Part § 305.23... product of information with respect to energy consumption, other than the information required to be...

  9. 16 CFR 305.23 - Effect on other law.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... DISCLOSURES REGARDING ENERGY CONSUMPTION AND WATER USE OF CERTAIN HOME APPLIANCES AND OTHER PRODUCTS REQUIRED UNDER THE ENERGY POLICY AND CONSERVATION ACT (âAPPLIANCE LABELING RULEâ) Effect of This Part § 305.23... product of information with respect to energy consumption, other than the information required to be...

  10. 16 CFR 305.23 - Effect on other law.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... DISCLOSURES REGARDING ENERGY CONSUMPTION AND WATER USE OF CERTAIN HOME APPLIANCES AND OTHER PRODUCTS REQUIRED UNDER THE ENERGY POLICY AND CONSERVATION ACT (âAPPLIANCE LABELING RULEâ) Effect of This Part § 305.23... product of information with respect to energy consumption, other than the information required to be...

  11. 76 FR 53851 - Effective Date of Requirement for Premarket Approval for Cardiovascular Permanent Pacemaker...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 870 [Docket No. FDA-2011-N-0505] Effective Date of Requirement for Premarket Approval for Cardiovascular Permanent... preamendments device: Cardiovascular permanent pacemaker electrode. The document was published with an incorrect...

  12. 10 CFR 835.702 - Individual monitoring records.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... emergency exposures. (b) Recording of the non-uniform equivalent dose to the skin is not required if the... internal dose (committed effective dose or committed equivalent dose) is not required for any monitoring...: (i) The effective dose from external sources of radiation (equivalent dose to the whole body may be...

  13. 10 CFR 835.702 - Individual monitoring records.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... emergency exposures. (b) Recording of the non-uniform equivalent dose to the skin is not required if the... internal dose (committed effective dose or committed equivalent dose) is not required for any monitoring...: (i) The effective dose from external sources of radiation (equivalent dose to the whole body may be...

  14. 10 CFR 835.702 - Individual monitoring records.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... emergency exposures. (b) Recording of the non-uniform equivalent dose to the skin is not required if the... internal dose (committed effective dose or committed equivalent dose) is not required for any monitoring...: (i) The effective dose from external sources of radiation (equivalent dose to the whole body may be...

  15. 10 CFR 835.702 - Individual monitoring records.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... emergency exposures. (b) Recording of the non-uniform equivalent dose to the skin is not required if the... internal dose (committed effective dose or committed equivalent dose) is not required for any monitoring...: (i) The effective dose from external sources of radiation (equivalent dose to the whole body may be...

  16. 10 CFR 835.702 - Individual monitoring records.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... emergency exposures. (b) Recording of the non-uniform equivalent dose to the skin is not required if the... internal dose (committed effective dose or committed equivalent dose) is not required for any monitoring...: (i) The effective dose from external sources of radiation (equivalent dose to the whole body may be...

  17. 26 CFR 1.527-8 - Effective date; filing requirements; and miscellaneous provisions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Effective date; filing requirements; and miscellaneous provisions. 1.527-8 Section 1.527-8 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Farmers' Cooperatives § 1.527-8...

  18. 41 CFR 101-4.125 - Effect of other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Effect of other requirements. 101-4.125 Section 101-4.125 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 4-NONDISCRIMINATION ON THE BASIS OF SEX IN...

  19. 21 CFR 862.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Effective dates of requirement for premarket approval. 862.3 Section 862.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES General Provisions...

  20. 21 CFR 862.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Effective dates of requirement for premarket approval. 862.3 Section 862.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES General Provisions...

  1. 21 CFR 862.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Effective dates of requirement for premarket approval. 862.3 Section 862.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES General Provisions...

  2. 21 CFR 862.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Effective dates of requirement for premarket approval. 862.3 Section 862.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES General Provisions...

  3. 17 CFR 201.153 - Filing of papers: Signature requirement and effect.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Filing of papers: Signature requirement and effect. 201.153 Section 201.153 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION RULES OF PRACTICE Rules of Practice General Rules § 201.153 Filing of papers: Signature...

  4. Identity Theft: Trends and Issues

    DTIC Science & Technology

    2010-01-05

    mitigate the effects of identity theft, one option Congress may consider is whether to strengthen data breach notification requirements. Such requirements...identity theft complaints to the FTC as well as in the number of reported data breaches placing personally identifiable information at risk. This report...23 Effects of Data Breaches ..................................................................................................... 24

  5. 26 CFR 1.303-2 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 4 2014-04-01 2014-04-01 false Requirements. 1.303-2 Section 1.303-2 Internal... TAXES (CONTINUED) Effects on Recipients § 1.303-2 Requirements. (a) Section 303 applies only where the... such 35 percent and 50 percent requirements, stock of two or more corporations shall be treated as the...

  6. 26 CFR 1.303-2 - Requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 4 2013-04-01 2013-04-01 false Requirements. 1.303-2 Section 1.303-2 Internal... TAXES (CONTINUED) Effects on Recipients § 1.303-2 Requirements. (a) Section 303 applies only where the... such 35 percent and 50 percent requirements, stock of two or more corporations shall be treated as the...

  7. 26 CFR 1.303-2 - Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 4 2012-04-01 2012-04-01 false Requirements. 1.303-2 Section 1.303-2 Internal... TAXES (Continued) Effects on Recipients § 1.303-2 Requirements. (a) Section 303 applies only where the... such 35 percent and 50 percent requirements, stock of two or more corporations shall be treated as the...

  8. 26 CFR 1.303-2 - Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 4 2011-04-01 2011-04-01 false Requirements. 1.303-2 Section 1.303-2 Internal... TAXES Effects on Recipients § 1.303-2 Requirements. (a) Section 303 applies only where the distribution... such 35 percent and 50 percent requirements, stock of two or more corporations shall be treated as the...

  9. Issues in Psychology Licensure: Requirements, Applicant Rights, Future Trends, and Epilogue.

    ERIC Educational Resources Information Center

    Tentoni, Stuart C.

    This paper provides an analysis of the effects of licensure for psychologists. Common requirements are reviewed. Meeting the requirements may require attention to the laws of the state in which practice is intended before finishing the doctorate. Making a graduate education dossier is recommended and an example is appended. The "Examination…

  10. 45 CFR 1386.30 - State plan requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false State plan requirements. 1386.30 Section 1386.30... § 1386.30 State plan requirements. (a) In order to receive Federal financial assistance under this... in effect, a State Plan which meets the requirements of sections 122 and 124 of the Act (42 U.S.C...

  11. 45 CFR 1386.30 - State plan requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false State plan requirements. 1386.30 Section 1386.30... § 1386.30 State plan requirements. (a) In order to receive Federal financial assistance under this... in effect, a State Plan which meets the requirements of sections 122 and 124 of the Act (42 U.S.C...

  12. 45 CFR 1386.30 - State plan requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false State plan requirements. 1386.30 Section 1386.30... § 1386.30 State plan requirements. (a) In order to receive Federal financial assistance under this... in effect, a State Plan which meets the requirements of sections 122 and 124 of the Act (42 U.S.C...

  13. Improving Requirements Generation Thoroughness in User-Centered Workshops: The Role of Prompting and Shared User Stories

    ERIC Educational Resources Information Center

    Read, Aaron

    2013-01-01

    The rise of stakeholder centered software development has led to organizations engaging users early in the development process to help define system requirements. To facilitate user involvement in the requirements elicitation process, companies can use Group Support Systems (GSS) to conduct requirements elicitation workshops. The effectiveness of…

  14. Factors modulating the effect of divided attention during retrieval of words.

    PubMed

    Fernandes, Myra A; Moscovitch, Morris

    2002-07-01

    In this study, we examined variables modulating interference effects on episodic memory under divided attention conditions during retrieval for a list of unrelated words. In Experiment 1, we found that distracting tasks that required animacy or syllable decisions to visually presented words, without a memory load, produced large interference on free recall performance. In Experiment 2, a distracting task requiring phonemic decisions about nonsense words produced a far larger interference effect than one that required semantic decisions about pictures. In Experiment 3, we replicated the effect of the nonsense-word distracting task on memory and showed that an equally resource-demanding picture-based task produced significant interference with memory retrieval, although the effect was smaller in magnitude. Taken together, the results suggest that free recall is disrupted by competition for phonological or word-form representations during retrieval and, to a lesser extent, by competition for semantic representations.

  15. Economic evaluations in pain management: principles and methods.

    PubMed

    Asche, Carl V; Seal, Brian; Jackson, Kenneth C; Oderda, Gary M

    2006-01-01

    This paper describes how investigators may design, conduct, and report economic evaluations of pharmacotherapy for pain and symptom management. Because economic evaluation of therapeutic interventions is becoming increasingly important, there is a need for guidance on how economic evaluations can be optimally conducted. The steps required to conduct an economic evaluation are described to provide this guidance. Economic evaluations require two or more therapeutic interventions to be compared in relation to costs and effects. There are five types of economic evaluations, based on analysis of: (1) cost-effectiveness, (2) cost-utility, (3) cost-minimization, (4) cost-consequence, and (5) cost-benefit analyses. The six required steps are: identify the perspective of the study; identify the alternatives that will be compared; identify the relevant costs and effects; determine how to collect the cost and effect data; determine how to perform calculation for cost and effects data; and determine the manner in which to depict the results and draw comparisons.

  16. Response allocation to concurrent fixed-ratio reinforcement schedules with work requirements by adults with mental retardation and typical preschool children.

    PubMed Central

    Cuvo, A J; Lerch, L J; Leurquin, D A; Gaffaney, T J; Poppen, R L

    1998-01-01

    The present experiments examined the effect of work requirements in combination with reinforcement schedule on the choice behavior of adults with mental retardation and preschool children. The work requirements of age-appropriate tasks (i.e., sorting silverware, jumping hurdles, tossing beanbags) were manipulated. Participants were presented with their choice of two response options for each trial that varied simultaneously on both work requirement and reinforcement schedule. Results showed that when responding to both choices occurred on the same reinforcement schedule, participants allocated most of their responses to the option with the easier work requirement. When the response option requiring less work was on a leaner reinforcement schedule, most participants shifted their choice to exert more work. There were individual differences across participants regarding their pattern of responding and when they switched from the lesser to the greater work requirement. Data showed that participants' responding was largely controlled by the reinforcement received for responding to each level of work. Various conceptualizations regarding the effects of work requirements on choice behavior are discussed. PMID:9532750

  17. Supplements and other changes to an approved application. Final rule.

    PubMed

    2004-04-08

    The Food and Drug Administration (FDA) is amending its regulations on supplements and other changes to an approved application to implement the manufacturing changes provision of the Food and Drug Administration Modernization Act of 1997 (the Modernization Act). The final rule requires manufacturers to assess the effects of manufacturing changes on the identity, strength, quality, purity, and potency of a drug or biological product as those factors relate to the safety or effectiveness of the product. The final rule sets forth requirements for changes requiring supplement submission and approval before the distribution of the product made using the change, changes requiring supplement submission at least 30 days prior to the distribution of the product, changes requiring supplement submission at the time of distribution, and changes to be described in an annual report.

  18. "PowerUp"!: A Tool for Calculating Minimum Detectable Effect Sizes and Minimum Required Sample Sizes for Experimental and Quasi-Experimental Design Studies

    ERIC Educational Resources Information Center

    Dong, Nianbo; Maynard, Rebecca

    2013-01-01

    This paper and the accompanying tool are intended to complement existing supports for conducting power analysis tools by offering a tool based on the framework of Minimum Detectable Effect Sizes (MDES) formulae that can be used in determining sample size requirements and in estimating minimum detectable effect sizes for a range of individual- and…

  19. Automatic Omega Station and LOP (Line of Position) Selection,

    DTIC Science & Technology

    1987-09-01

    LL- jAj C) LJ b- I- I LL I-0 a- 5~52 3.2.2 SOLAR EFFECTS The sun effects Omega modal interference in several significant ways. Firstly the effect...nx(n+l) TD and F are 2x(n+l) -67- %..T C ..4 . (43). a -Je MT Therefore to form BTH requires 4n multiplies and (H TH)- 1 requires 6 multiplies and

  20. Ability Versus Will: The Reason Insurgents Surrender

    DTIC Science & Technology

    2010-06-01

    quit as well. The adage that it takes two to tango does not necessarily hold for decisions involving war, however. More than one party is required to...intended effects . Furthermore, the indirect casualties have a timeline that can extend several months, if not years. The effects can take some...not as prominent as if there were numerous, stark differences between the two . To be an effective impetus for insurgency ideology usually requires

  1. 31 CFR 30.17 - Q-17: How do the effective date provisions apply with respect to the requirements under section...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Q-17: How do the effective date... GOVERNANCE § 30.17 Q-17: How do the effective date provisions apply with respect to the requirements under... terms. (b) Bonus payment limitation. The bonus payment limitation provision under § 30.10 (Q-10) of this...

  2. 31 CFR 30.17 - Q-17: How do the effective date provisions apply with respect to the requirements under section...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Q-17: How do the effective date... GOVERNANCE § 30.17 Q-17: How do the effective date provisions apply with respect to the requirements under... terms. (b) Bonus payment limitation. The bonus payment limitation provision under § 30.10 (Q-10) of this...

  3. 31 CFR 30.17 - Q-17: How do the effective date provisions apply with respect to the requirements under section...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Q-17: How do the effective date... GOVERNANCE § 30.17 Q-17: How do the effective date provisions apply with respect to the requirements under... terms. (b) Bonus payment limitation. The bonus payment limitation provision under § 30.10 (Q-10) of this...

  4. 31 CFR 30.17 - Q-17: How do the effective date provisions apply with respect to the requirements under section...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Q-17: How do the effective date... GOVERNANCE § 30.17 Q-17: How do the effective date provisions apply with respect to the requirements under... terms. (b) Bonus payment limitation. The bonus payment limitation provision under § 30.10 (Q-10) of this...

  5. Sample size requirements for indirect association studies of gene-environment interactions (G x E).

    PubMed

    Hein, Rebecca; Beckmann, Lars; Chang-Claude, Jenny

    2008-04-01

    Association studies accounting for gene-environment interactions (G x E) may be useful for detecting genetic effects. Although current technology enables very dense marker spacing in genetic association studies, the true disease variants may not be genotyped. Thus, causal genes are searched for by indirect association using genetic markers in linkage disequilibrium (LD) with the true disease variants. Sample sizes needed to detect G x E effects in indirect case-control association studies depend on the true genetic main effects, disease allele frequencies, whether marker and disease allele frequencies match, LD between loci, main effects and prevalence of environmental exposures, and the magnitude of interactions. We explored variables influencing sample sizes needed to detect G x E, compared these sample sizes with those required to detect genetic marginal effects, and provide an algorithm for power and sample size estimations. Required sample sizes may be heavily inflated if LD between marker and disease loci decreases. More than 10,000 case-control pairs may be required to detect G x E. However, given weak true genetic main effects, moderate prevalence of environmental exposures, as well as strong interactions, G x E effects may be detected with smaller sample sizes than those needed for the detection of genetic marginal effects. Moreover, in this scenario, rare disease variants may only be detectable when G x E is included in the analyses. Thus, the analysis of G x E appears to be an attractive option for the detection of weak genetic main effects of rare variants that may not be detectable in the analysis of genetic marginal effects only.

  6. Requirements for effective use of CFD in aerospace design

    NASA Technical Reports Server (NTRS)

    Raj, Pradeep

    1995-01-01

    This paper presents a perspective on the requirements that Computational Fluid Dynamics (CFD) technology must meet for its effective use in aerospace design. General observations are made on current aerospace design practices and deficiencies are noted that must be rectified for the U.S. aerospace industry to maintain its leadership position in the global marketplace. In order to rectify deficiencies, industry is transitioning to an integrated product and process development (IPPD) environment and design processes are undergoing radical changes. The role of CFD in producing data that design teams need to support flight vehicle development is briefly discussed. An overview of the current state of the art in CFD is given to provide an assessment of strengths and weaknesses of the variety of methods currently available, or under development, to produce aerodynamic data. Effectiveness requirements are examined from a customer/supplier view point with design team as customer and CFD practitioner as supplier. Partnership between the design team and CFD team is identified as an essential requirement for effective use of CFD. Rapid turnaround, reliable accuracy, and affordability are offered as three key requirements that CFD community must address if CFD is to play its rightful role in supporting the IPPD design environment needed to produce high quality yet affordable designs.

  7. [Estimating the impacts of future climate change on water requirement and water deficit of winter wheat in Henan Province, China].

    PubMed

    Ji, Xing-jie; Cheng, Lin; Fang, Wen-song

    2015-09-01

    Based on the analysis of water requirement and water deficit during development stage of winter wheat in recent 30 years (1981-2010) in Henan Province, the effective precipitation was calculated using the U.S. Department of Agriculture Soil Conservation method, the water requirement (ETC) was estimated by using FAO Penman-Monteith equation and crop coefficient method recommended by FAO, combined with the climate change scenario A2 (concentration on the economic envelopment) and B2 ( concentration on the sustainable development) of Special Report on Emissions Scenarios (SRES) , the spatial and temporal characteristics of impacts of future climate change on effective precipitation, water requirement and water deficit of winter wheat were estimated. The climatic impact factors of ETc and WD also were analyzed. The results showed that under A2 and B2 scenarios, there would be a significant increase in anomaly percentage of effective precipitation, water requirement and water deficit of winter wheat during the whole growing period compared with the average value from 1981 to 2010. Effective precipitation increased the most in 2030s under A2 and B2 scenarios by 33.5% and 39.2%, respectively. Water requirement increased the most in 2010s under A2 and B2 scenarios by 22.5% and 17.5%, respectively, and showed a significant downward trend with time. Water deficit increased the most under A2 scenario in 2010s by 23.6% and under B2 scenario in 2020s by 13.0%. Partial correlation analysis indicated that solar radiation was the main cause for the variation of ETc and WD in future under A2 and B2 scenarios. The spatial distributions of effective precipitation, water requirement and water deficit of winter wheat during the whole growing period were spatially heterogeneous because of the difference in geographical and climatic environments. A possible tendency of water resource deficiency may exist in Henan Province in the future.

  8. Effect-site concentration of propofol required for LMA-Supreme™ insertion with and without remifentanil: a randomized controlled trial.

    PubMed

    Zaballos, Matilde; Bastida, Emilia; Agustí, Salomé; Portas, Maite; Jiménez, Consuelo; López-Gil, Maite

    2015-10-06

    A new supraglottic device, the LMA-Supreme™, has recently become available for clinical use. Information on anaesthetic and co-adjuvant requirements for insertion of the LMA-Supreme™ is limited. The present study aimed to evaluate the optimal effect-site concentration of propofol in 50 % (EC50) of adults necessary for successful insertion of the LMA-Supreme™ and to examine remifentanil's effect on propofol requirements. Fifty-eight elective patients (aged 18-60 years; ASA (American Society Anaesthesiologists) physical status classification I and II) scheduled for day surgery were randomly assigned to one of two groups: propofol with saline or propofol with remifentanil. Anaesthesia was induced by target-controlled infusion according to predetermined effect-site concentrations of propofol and remifentanil (5 ng.mL(-1)). The EC50 was calculated using Dixon's up-and-down method. Ten minutes following drug administration, LMA-Supreme™ insertion was attempted without the use of muscle relaxant drugs. In the propofol + saline group, the EC50 of propofol required for LMA-Supreme™ insertion was 6.32 ± 0.67 μg.mL(-1) (95 % CI, 5.69-6.94 μg.mL(-1)). With the addition of remifentanil at an effect-site concentration of 5 ng.mL(-1), the EC50 of propofol required for LMA-Supreme™ insertion was 2.50 ± 0.80 μg.mL(-1) (95 % CI, 1.82-3.17 μg.mL(-1); p < 0.0001). The propofol requirement for smooth insertion of the LMA-Supreme™ was 60 % less when remifentanil (5 ng.mL(-1)) was co-administered. Identified as NCT01974648 at www.clinicaltrials.gov .

  9. 23 CFR 1205.4 - Funding requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Funding requirements. 1205.4 Section 1205.4 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUIDELINES HIGHWAY SAFETY PROGRAMS; DETERMINATIONS OF EFFECTIVENESS § 1205.4 Funding requirements...

  10. 23 CFR 1205.4 - Funding requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Funding requirements. 1205.4 Section 1205.4 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUIDELINES HIGHWAY SAFETY PROGRAMS; DETERMINATIONS OF EFFECTIVENESS § 1205.4 Funding requirements...

  11. 23 CFR 1205.4 - Funding requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Funding requirements. 1205.4 Section 1205.4 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUIDELINES HIGHWAY SAFETY PROGRAMS; DETERMINATIONS OF EFFECTIVENESS § 1205.4 Funding requirements...

  12. Development of DSRC device and communication system performance measures recommendations for DSRC OBE performance and security requirements.

    DOT National Transportation Integrated Search

    2016-05-22

    This report presents recommendations for minimum DSRC device communication performance and security requirements to ensure effective operation of the DSRC system. The team identified recommended DSRC communications requirements aligned to use cases, ...

  13. 2011 Report Card on the Effectiveness of Teacher Training Programs

    ERIC Educational Resources Information Center

    Tennessee State Board of Education, 2011

    2011-01-01

    The Tennessee General Assembly passed legislation in 2007 requiring that the State Board of Education produce an assessment on the effectiveness of teacher training programs. The law requires that the report includes data on the performance of each program's graduates in the following areas: placement and retention rates, Praxis II results, and…

  14. 49 CFR 25.535 - Effect of state or local law or other requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 25.535 Effect... or other requirement that imposes prohibitions or limits upon employment of members of one sex that...

  15. 34 CFR 104.10 - Effect of state or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 104.10... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the...

  16. 34 CFR 104.10 - Effect of state or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 104.10... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the...

  17. 34 CFR 104.10 - Effect of state or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 104.10... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the...

  18. 34 CFR 104.10 - Effect of state or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 104.10... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the...

  19. 34 CFR 104.10 - Effect of state or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 104.10... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the...

  20. 14 CFR 1251.109 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP General Provisions § 1251.109... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the eligibility of qualified handicapped persons to receive services or to practice any occupation or profession...

  1. 14 CFR 1251.109 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP General Provisions § 1251.109... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the eligibility of qualified handicapped persons to receive services or to practice any occupation or profession...

  2. 14 CFR 1251.109 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP General Provisions § 1251.109... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the eligibility of qualified handicapped persons to receive services or to practice any occupation or profession...

  3. 14 CFR 1251.109 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP General Provisions § 1251.109... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the eligibility of qualified handicapped persons to receive services or to practice any occupation or profession...

  4. 14 CFR § 1251.109 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP General Provisions... local law or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the eligibility of qualified handicapped persons to receive services or to practice any occupation or profession...

  5. 2 CFR 175.10 - Statutory requirement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) under which funding is provided to a private entity, section 106(g) of the TVPA, as amended, requires... period of time that the award is in effect; (b) Procures a commercial sex act during the period of time that the award is in effect; or (c) Uses forced labor in the performance of the award or subawards...

  6. 2 CFR 175.10 - Statutory requirement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) under which funding is provided to a private entity, section 106(g) of the TVPA, as amended, requires... period of time that the award is in effect; (b) Procures a commercial sex act during the period of time that the award is in effect; or (c) Uses forced labor in the performance of the award or subawards...

  7. 21 CFR 866.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Effective dates of requirement for premarket approval. 866.3 Section 866.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES General Provisions § 866.3...

  8. 21 CFR 866.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Effective dates of requirement for premarket approval. 866.3 Section 866.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES General Provisions § 866.3...

  9. 21 CFR 866.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Effective dates of requirement for premarket approval. 866.3 Section 866.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES General Provisions § 866.3...

  10. 21 CFR 866.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Effective dates of requirement for premarket approval. 866.3 Section 866.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES General Provisions § 866.3...

  11. 21 CFR 866.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Effective dates of requirement for premarket approval. 866.3 Section 866.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES General Provisions § 866.3...

  12. 78 FR 66841 - Turtles Intrastate and Interstate Requirements; Confirmation of Effective Date

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 1240 [Docket No. FDA-2013-N-0639] Turtles Intrastate and Interstate Requirements; Confirmation of Effective Date AGENCY... turtle eggs and live turtles with a carapace length of less than 4 inches to remove procedures for...

  13. 10 CFR 50.65 - Requirements for monitoring the effectiveness of maintenance at nuclear power plants.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... maintenance at nuclear power plants. 50.65 Section 50.65 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... Construction Permits § 50.65 Requirements for monitoring the effectiveness of maintenance at nuclear power..., including normal shutdown operations. (a)(1) Each holder of an operating license for a nuclear power plant...

  14. 10 CFR 50.65 - Requirements for monitoring the effectiveness of maintenance at nuclear power plants.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... maintenance at nuclear power plants. 50.65 Section 50.65 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... Construction Permits § 50.65 Requirements for monitoring the effectiveness of maintenance at nuclear power..., including normal shutdown operations. (a)(1) Each holder of an operating license for a nuclear power plant...

  15. 10 CFR 50.65 - Requirements for monitoring the effectiveness of maintenance at nuclear power plants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... maintenance at nuclear power plants. 50.65 Section 50.65 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... Construction Permits § 50.65 Requirements for monitoring the effectiveness of maintenance at nuclear power..., including normal shutdown operations. (a)(1) Each holder of an operating license for a nuclear power plant...

  16. 10 CFR 50.65 - Requirements for monitoring the effectiveness of maintenance at nuclear power plants.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... maintenance at nuclear power plants. 50.65 Section 50.65 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... Construction Permits § 50.65 Requirements for monitoring the effectiveness of maintenance at nuclear power..., including normal shutdown operations. (a)(1) Each holder of an operating license for a nuclear power plant...

  17. 21 CFR 522.1884 - Prednisolone sodium succinate injection.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... inflammatory, allergic and less severe stress conditions, where immediate effect is not required, at 1 to 5... other stress conditions at intervals of 12, 24, or 48 hours, depending upon the size of the animal, the... hours and continued for 3 to 5 days if necessary. If permanent corticosteroid effect is required oral...

  18. 49 CFR 393.5 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... waste, recycling, construction/demolition and scrap industries, which is used in conjunction with... requirements of § 571.224 in effect on the date of manufacture, or a subsequent edition. (2) A motor vehicle... surface requirements of § 571.224 (paragraphs S5.1.1 through S5.1.3), in effect on the date of manufacture...

  19. 49 CFR 393.5 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... waste, recycling, construction/demolition and scrap industries, which is used in conjunction with... requirements of § 571.224 in effect on the date of manufacture, or a subsequent edition. (2) A motor vehicle... surface requirements of § 571.224 (paragraphs S5.1.1 through S5.1.3), in effect on the date of manufacture...

  20. 49 CFR 393.5 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... waste, recycling, construction/demolition and scrap industries, which is used in conjunction with... requirements of § 571.224 in effect on the date of manufacture, or a subsequent edition. (2) A motor vehicle... surface requirements of § 571.224 (paragraphs S5.1.1 through S5.1.3), in effect on the date of manufacture...

  1. 41 CFR 101-4.535 - Effect of state or local law or other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Effect of state or local law or other requirements. 101-4.535 Section 101-4.535 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 4...

  2. 21 CFR 3.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... both are required to achieve the intended use, indication, or effect and where upon approval of the... biological product where both are required to achieve the intended use, indication, or effect. (f) Device has the meaning given the term in section 201(h) of the act. (g) Drug has the meaning given the term in...

  3. 21 CFR 3.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... both are required to achieve the intended use, indication, or effect and where upon approval of the... biological product where both are required to achieve the intended use, indication, or effect. (f) Device has the meaning given the term in section 201(h) of the act. (g) Drug has the meaning given the term in...

  4. 21 CFR 3.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... both are required to achieve the intended use, indication, or effect and where upon approval of the... biological product where both are required to achieve the intended use, indication, or effect. (f) Device has the meaning given the term in section 201(h) of the act. (g) Drug has the meaning given the term in...

  5. 21 CFR 878.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Effective dates of requirement for premarket approval. 878.3 Section 878.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES General Provisions § 878.3...

  6. 21 CFR 878.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Effective dates of requirement for premarket approval. 878.3 Section 878.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES General Provisions § 878.3...

  7. 21 CFR 878.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Effective dates of requirement for premarket approval. 878.3 Section 878.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES General Provisions § 878.3...

  8. 21 CFR 878.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Effective dates of requirement for premarket approval. 878.3 Section 878.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES General Provisions § 878.3...

  9. 21 CFR 878.3 - Effective dates of requirement for premarket approval.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Effective dates of requirement for premarket approval. 878.3 Section 878.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES General Provisions § 878.3...

  10. COMPARISON OF ALTERNATIVE MANURE MANAGEMENT SYSTEMS: EFFECT ON THE ENVIRONMENT, TOTAL ENERGY REQUIREMENT, NUTRIENT CONSERVATION, CONTRIBUTION TO CORN SILAGE PRODUCTION AND ECONOMICS

    EPA Science Inventory

    This study compares alternative dairy manure management systems operated under full scale commercial conditions. The study investigates weight of manure handled per cow per year, labor and energy requirements, effect on the environment, nutrient conservation, corn silage producti...

  11. Effects of a Caenorhabditis elegans dauer pheromone ascaroside on physiology and signal transduction pathways.

    PubMed

    Gallo, Marco; Riddle, Donald L

    2009-02-01

    Daumone is one of the three purified and artificially synthesized components of the Caenorhabditis elegans dauer pheromone. It affects the major signal transduction pathways known to discriminate between developmental arrest at the dauer stage and growth to the adult [the transforming growth factor beta (TGF-beta) and daf-2/IGF1R pathways], just as natural pheromone extracts do. Transcription of daf-7/TGF-beta is reduced in pre-dauer larvae, and nuclear localization of the DAF-16/FOXO transcription factor is increased in embryos and L1 larvae exposed to synthetic daumone. However, daumone does not require the cilia in the amphidial neurons to produce these effects nor does it require the Galpha protein GPA-3 to induce dauer entry, although GPA-3 is required for dauer induction by natural dauer pheromone extracts. Synthetic daumone has physiological effects that have not been observed with natural pheromone. It is toxic at the concentrations required for bioassay and is lethal to mutants with defective cuticles. The molecular and physiological effects of daumone and natural dauer pheromone are only partially overlapping.

  12. Importance and globalization status of good manufacturing practice (GMP) requirements for pharmaceutical excipients

    PubMed Central

    Abdellah, Abubaker; Noordin, Mohamed Ibrahim; Wan Ismail, Wan Azman

    2013-01-01

    Pharmaceutical excipients are no longer inert materials but it is effective and able to improve the characteristics of the products’ quality, stability, functionality, safety, solubility and acceptance of patients. It can interact with the active ingredients and alter the medicament characteristics. The globalization of medicines’ supply enhances the importance of globalized good manufacturing practice (GMP) requirements for pharmaceutical excipients. This review was intended to assess the globalization status of good manufacturing practice (GMP) requirements for pharmaceutical excipients. The review outcomes demonstrate that there is a lack of accurately defined methods to evaluate and measure excipients’ safety. Furthermore good manufacturing practice requirements for excipients are not effectively globalized. PMID:25685037

  13. The effect of technology advancements on the comparative advantages of electric versus chemical propulsion for a large cargo orbit transfer vehicle

    NASA Technical Reports Server (NTRS)

    Rehder, J. J.; Wurster, K. E.

    1978-01-01

    Techniques for sizing electrically or chemically propelled orbit transfer vehicles and analyzing fleet requirements are used in a comparative analysis of the two concepts for various levels of traffic to geosynchronous orbit. The vehicle masses, fuel requirements, and fleet sizes are determined and translated into launch vehicle payload requirements. Technology projections beyond normal growth are made and their effect on the comparative advantages of the concepts is determined. A preliminary cost analysis indicates that although electric propulsion greatly reduces launch vehicle requirements substantial improvements in the cost and reusability of power systems must occur to make an electrically propelled vehicle competitive.

  14. Levothyroxine Dosing Following Bariatric Surgery.

    PubMed

    Gadiraju, Silpa; Lee, Clare J; Cooper, David S

    2016-10-01

    Based on the mechanisms of drug absorption, increased levothyroxine requirements are expected after bariatric surgery. However, there are conflicting data on this topic. This review evaluates the effects of bariatric surgery on levothyroxine dosing. Data were obtained from PubMed, Scopus, and review of published bibliographies. Six of 10 studies demonstrated decreased postoperative requirements. Most demonstrated correlations between weight loss and dose. Only 3 case reports and 1 case series demonstrated increased levothyroxine requirements, attributed to malabsorption. The loss of both fat and lean body mass may counteract malabsorptive effects from surgery, resulting in decreased postoperative levothyroxine requirements. In addition, the reversal of impaired levothyroxine pharmacokinetics and an altered set point of thyroid hormone homeostasis may also contribute to postoperative levothyroxine reductions.

  15. Research on Capturing of Customer Requirements Based on Innovation Theory

    NASA Astrophysics Data System (ADS)

    junwu, Ding; dongtao, Yang; zhenqiang, Bao

    To exactly and effectively capture customer requirements information, a new customer requirements capturing modeling method was proposed. Based on the analysis of function requirement models of previous products and the application of technology system evolution laws of the Theory of Innovative Problem Solving (TRIZ), the customer requirements could be evolved from existing product designs, through modifying the functional requirement unit and confirming the direction of evolution design. Finally, a case study was provided to illustrate the feasibility of the proposed approach.

  16. Nonparametric methods for doubly robust estimation of continuous treatment effects.

    PubMed

    Kennedy, Edward H; Ma, Zongming; McHugh, Matthew D; Small, Dylan S

    2017-09-01

    Continuous treatments (e.g., doses) arise often in practice, but many available causal effect estimators are limited by either requiring parametric models for the effect curve, or by not allowing doubly robust covariate adjustment. We develop a novel kernel smoothing approach that requires only mild smoothness assumptions on the effect curve, and still allows for misspecification of either the treatment density or outcome regression. We derive asymptotic properties and give a procedure for data-driven bandwidth selection. The methods are illustrated via simulation and in a study of the effect of nurse staffing on hospital readmissions penalties.

  17. Role of preemptive tapentadol in reduction of postoperative analgesic requirements after laparoscopic cholecystectomy

    PubMed Central

    Yadav, Ghanshyam; Jain, Gaurav; Samprathi, Abhishek; Baghel, Annavi; Singh, Dinesh Kumar

    2016-01-01

    Background and Aims: Poorly managed acute postoperative pain may result in prolonged morbidity. Various pharmacotherapies have targeted this, but research on an ideal preemptive analgesic continues, taking into account drug-related side effects. Considering the better tolerability profile of tapentadol, we assessed its role as a preemptive analgesic in the reduction of postoperative analgesic requirements, after laparoscopic cholecystectomy. Material and Methods: In a prospective-double-blinded fashion, sixty patients posted for above surgery, were randomized to receive tablet tapentadol 75 mg (Group A) or starch tablets (Group B) orally, an hour before induction of general anesthesia. Perioperative analgesic requirement, time to first analgesia, pain, and sedation score were compared for first 24 h during the postoperative period and analyzed by one-way analysis of variance test. A P < 0.05 was considered significant. Results: Sixty patients were analyzed. The perioperative analgesic requirement was significantly lower in Group A. Verbal numerical score was significantly lower in Group A at the time point, immediately after shifting the patient to the postanesthesia care unit. Ramsay sedation scores were similar between the groups. No major side effects were observed except for nausea and vomiting in 26 cases (10 in Group A, 16 in Group B). Conclusion: Single preemptive oral dose of tapentadol (75 mg) is effective in reducing perioperative analgesic requirements and acute postoperative pain, without added side effects. It could be an appropriate preemptive analgesic, subjected to future trials concentrating upon its dose-response effects. PMID:28096581

  18. Quality Program Provisions for Aeronautical and Space System Contractors

    NASA Technical Reports Server (NTRS)

    1969-01-01

    This publication sets forth quality program requirements for NASA aeronautical and space programs, systems, subsystems, and related services. These requirements provide for the effective operation of a quality program which ensures that quality criteria and requirements are recognized, definitized, and performed satisfactorily.

  19. Transverse and Quantum Effects in Light Control by Light; (A) Parallel Beams: Pump Dynamics for Three Level Superfluorescence; and (B) Counterflow Beams: An Algorithm for Transverse, Full Transient Effects in Optical Bi-Stability in a Fabryperot Cavity.

    DTIC Science & Technology

    1983-01-01

    The resolution of the compu- and also leads to an expression for "dz,"*. tational grid is thereby defined according to e the actual requirements of...computational economy are achieved simultaneously by redistributing the computational grid points according to the physical requirements of the problem...computational Eulerian grid points according to implemented using a two-dimensionl time- the physical requirements of the nonlinear dependent finite

  20. A Scenario-Based Process for Requirements Development: Application to Mission Operations Systems

    NASA Technical Reports Server (NTRS)

    Bindschadler, Duane L.; Boyles, Carole A.

    2008-01-01

    The notion of using operational scenarios as part of requirements development during mission formulation (Phases A & B) is widely accepted as good system engineering practice. In the context of developing a Mission Operations System (MOS), there are numerous practical challenges to translating that notion into the cost-effective development of a useful set of requirements. These challenges can include such issues as a lack of Project-level focus on operations issues, insufficient or improper flowdown of requirements, flowdown of immature or poor-quality requirements from Project level, and MOS resource constraints (personnel expertise and/or dollars). System engineering theory must be translated into a practice that provides enough structure and standards to serve as guidance, but that retains sufficient flexibility to be tailored to the needs and constraints of a particular MOS or Project. We describe a detailed, scenario-based process for requirements development. Identifying a set of attributes for high quality requirements, we show how the portions of the process address many of those attributes. We also find that the basic process steps are robust, and can be effective even in challenging Project environments.

  1. The effect of the learner license Graduated Driver Licensing components on teen drivers' crashes.

    PubMed

    Ehsani, Johnathon Pouya; Bingham, C Raymond; Shope, Jean T

    2013-10-01

    Most studies evaluating the effectiveness of Graduated Driver Licensing (GDL) have focused on the overall system. Studies examining individual components have rarely accounted for the confounding of multiple, simultaneously implemented components. The purpose of this paper is to quantify the effects of a required learner license duration and required hours of supervised driving on teen driver fatal crashes. States that introduced a single GDL component independent of any other during the period 1990-2009 were identified. Monthly and quarterly fatal crash rates per 100,000 population of 16- and 17-year-old drivers were analyzed using single-state time series analysis, adjusting for adult crash rates and gasoline prices. Using the parameter estimates from each state's time series model, the pooled effect of each GDL component on 16- and 17-year-old drivers' fatal crashes was estimated using a random effects meta-analytic model to combine findings across states. In three states, a six-month minimum learner license duration was associated with a significant decline in combined 16- and 17-year-old drivers' fatal crash rates. The pooled effect of the minimum learner license duration across all states in the sample was associated with a significant change in combined 16- and 17-year-old driver fatal crash rates of -.07 (95% Confidence Interval [CI] -.11, -.03). Following the introduction of 30 h of required supervised driving in one state, novice drivers' fatal crash rates increased 35%. The pooled effect across all states in the study sample of having a supervised driving hour requirement was not significantly different from zero (.04, 95% CI -.15, .22). These findings suggest that a learner license duration of at least six-months may be necessary to achieve a significant decline in teen drivers' fatal crash rates. Evidence of the effect of required hours of supervised driving on teen drivers' fatal crash rates was mixed. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Software reliability: Application of a reliability model to requirements error analysis

    NASA Technical Reports Server (NTRS)

    Logan, J.

    1980-01-01

    The application of a software reliability model having a well defined correspondence of computer program properties to requirements error analysis is described. Requirements error categories which can be related to program structural elements are identified and their effect on program execution considered. The model is applied to a hypothetical B-5 requirement specification for a program module.

  3. Robust estimation of the proportion of treatment effect explained by surrogate marker information.

    PubMed

    Parast, Layla; McDermott, Mary M; Tian, Lu

    2016-05-10

    In randomized treatment studies where the primary outcome requires long follow-up of patients and/or expensive or invasive obtainment procedures, the availability of a surrogate marker that could be used to estimate the treatment effect and could potentially be observed earlier than the primary outcome would allow researchers to make conclusions regarding the treatment effect with less required follow-up time and resources. The Prentice criterion for a valid surrogate marker requires that a test for treatment effect on the surrogate marker also be a valid test for treatment effect on the primary outcome of interest. Based on this criterion, methods have been developed to define and estimate the proportion of treatment effect on the primary outcome that is explained by the treatment effect on the surrogate marker. These methods aim to identify useful statistical surrogates that capture a large proportion of the treatment effect. However, current methods to estimate this proportion usually require restrictive model assumptions that may not hold in practice and thus may lead to biased estimates of this quantity. In this paper, we propose a nonparametric procedure to estimate the proportion of treatment effect on the primary outcome that is explained by the treatment effect on a potential surrogate marker and extend this procedure to a setting with multiple surrogate markers. We compare our approach with previously proposed model-based approaches and propose a variance estimation procedure based on a perturbation-resampling method. Simulation studies demonstrate that the procedure performs well in finite samples and outperforms model-based procedures when the specified models are not correct. We illustrate our proposed procedure using a data set from a randomized study investigating a group-mediated cognitive behavioral intervention for peripheral artery disease participants. Copyright © 2015 John Wiley & Sons, Ltd.

  4. 29 CFR 1606.5 - Citizenship requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 4 2014-07-01 2014-07-01 false Citizenship requirements. 1606.5 Section 1606.5 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION GUIDELINES ON DISCRIMINATION... citizenship requirements have the purpose or effect of discriminating against an individual on the basis of...

  5. 29 CFR 1606.5 - Citizenship requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Citizenship requirements. 1606.5 Section 1606.5 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION GUIDELINES ON DISCRIMINATION... citizenship requirements have the purpose or effect of discriminating against an individual on the basis of...

  6. 29 CFR 1606.5 - Citizenship requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 4 2011-07-01 2011-07-01 false Citizenship requirements. 1606.5 Section 1606.5 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION GUIDELINES ON DISCRIMINATION... citizenship requirements have the purpose or effect of discriminating against an individual on the basis of...

  7. 29 CFR 1606.5 - Citizenship requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 4 2012-07-01 2012-07-01 false Citizenship requirements. 1606.5 Section 1606.5 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION GUIDELINES ON DISCRIMINATION... citizenship requirements have the purpose or effect of discriminating against an individual on the basis of...

  8. 29 CFR 1606.5 - Citizenship requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 4 2013-07-01 2013-07-01 false Citizenship requirements. 1606.5 Section 1606.5 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION GUIDELINES ON DISCRIMINATION... citizenship requirements have the purpose or effect of discriminating against an individual on the basis of...

  9. 76 FR 50481 - Announcement of Requirements and Registration for “Lifeline Facebook App Challenge”; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Announcement of Requirements and Registration for ``Lifeline Facebook App Challenge''; Correction AGENCY: Office of the Assistant Secretary for Preparedness... Requirements and Registration for ``Lifeline Facebook App Challenge''. DATES: This correction is effective...

  10. 12 CFR 252.153 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... (CONTINUED) ENHANCED PRUDENTIAL STANDARDS (REGULATION YY) Company-Run Stress Test Requirements for Banking... December 31, 2012, must comply with the requirements of this subpart beginning with the stress test cycle... effect on May 19, 2010) must comply with the requirements of this subpart beginning with the stress test...

  11. 48 CFR 1804.470-4 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Contract clause. (a) Insert the clause at 1852.204-76, Security Requirements for Unclassified Information...) Have physical or electronic access to NASA's computer systems, networks, or IT infrastructure; or (2... security program meets or exceeds the requirements of NASA Procedural Requirements (NPR) 2810.1 in effect...

  12. 48 CFR 1804.470-4 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Contract clause. (a) Insert the clause at 1852.204-76, Security Requirements for Unclassified Information...) Have physical or electronic access to NASA's computer systems, networks, or IT infrastructure; or (2... security program meets or exceeds the requirements of NASA Procedural Requirements (NPR) 2810.1 in effect...

  13. 48 CFR 1804.470-4 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Contract clause. (a) Insert the clause at 1852.204-76, Security Requirements for Unclassified Information...) Have physical or electronic access to NASA's computer systems, networks, or IT infrastructure; or (2... security program meets or exceeds the requirements of NASA Procedural Requirements (NPR) 2810.1 in effect...

  14. 48 CFR 1804.470-4 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Contract clause. (a) Insert the clause at 1852.204-76, Security Requirements for Unclassified Information...) Have physical or electronic access to NASA's computer systems, networks, or IT infrastructure; or (2... security program meets or exceeds the requirements of NASA Procedural Requirements (NPR) 2810.1 in effect...

  15. 38 CFR 18.444 - Academic adjustments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Academic adjustments. 18....444 Academic adjustments. (a) Academic requirements. A recipient shall make necessary modifications to its academic requirements to ensure that these requirements do not discriminate or have the effect of...

  16. 38 CFR 18.444 - Academic adjustments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Academic adjustments. 18....444 Academic adjustments. (a) Academic requirements. A recipient shall make necessary modifications to its academic requirements to ensure that these requirements do not discriminate or have the effect of...

  17. 38 CFR 18.444 - Academic adjustments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Academic adjustments. 18....444 Academic adjustments. (a) Academic requirements. A recipient shall make necessary modifications to its academic requirements to ensure that these requirements do not discriminate or have the effect of...

  18. 38 CFR 18.444 - Academic adjustments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Academic adjustments. 18....444 Academic adjustments. (a) Academic requirements. A recipient shall make necessary modifications to its academic requirements to ensure that these requirements do not discriminate or have the effect of...

  19. Data governance requirements for distributed clinical research networks: triangulating perspectives of diverse stakeholders

    PubMed Central

    Kim, Katherine K; Browe, Dennis K; Logan, Holly C; Holm, Roberta; Hack, Lori; Ohno-Machado, Lucila

    2014-01-01

    There is currently limited information on best practices for the development of governance requirements for distributed research networks (DRNs), an emerging model that promotes clinical data reuse and improves timeliness of comparative effectiveness research. Much of the existing information is based on a single type of stakeholder such as researchers or administrators. This paper reports on a triangulated approach to developing DRN data governance requirements based on a combination of policy analysis with experts, interviews with institutional leaders, and patient focus groups. This approach is illustrated with an example from the Scalable National Network for Effectiveness Research, which resulted in 91 requirements. These requirements were analyzed against the Fair Information Practice Principles (FIPPs) and Health Insurance Portability and Accountability Act (HIPAA) protected versus non-protected health information. The requirements addressed all FIPPs, showing how a DRN's technical infrastructure is able to fulfill HIPAA regulations, protect privacy, and provide a trustworthy platform for research. PMID:24302285

  20. The effects of differing response-force requirements on fixed-ratio responding of rats.

    PubMed Central

    Alling, K; Poling, A

    1995-01-01

    Rats were exposed to two-component multiple schedules of food delivery. In the first experiment, 15 responses were required to produce food in both components. A downward force of 0.25 N (25 g) was always required to operate the response lever in one component. In the other, the required force was 0.25, 0.50, 1.00, or 2.00 N (25, 50, 100, or 200 g). In the second experiment, 0.25 N of force operated the lever in one component, but in the other, the force requirement for five consecutive responses at the beginning, middle, or end of each ratio was increased from 0.25 to 2.00 N. In the third experiment, the number of responses required to produce food was reduced from 15 to 5, and then to 1. Again, the effects of altering response force from 0.25 to 2.00 N were examined. In general, as response force increased in all experiments, mean response rates decreased and mean interresponse times increased. PMID:7751836

  1. On the minimum quantum requirement of photosynthesis.

    PubMed

    Zeinalov, Yuzeir

    2009-01-01

    An analysis of the shape of photosynthetic light curves is presented and the existence of the initial non-linear part is shown as a consequence of the operation of the non-cooperative (Kok's) mechanism of oxygen evolution or the effect of dark respiration. The effect of nonlinearity on the quantum efficiency (yield) and quantum requirement is reconsidered. The essential conclusions are: 1) The non-linearity of the light curves cannot be compensated using suspensions of algae or chloroplasts with high (>1.0) optical density or absorbance. 2) The values of the maxima of the quantum efficiency curves or the values of the minima of the quantum requirement curves cannot be used for estimation of the exact value of the maximum quantum efficiency and the minimum quantum requirement. The estimation of the maximum quantum efficiency or the minimum quantum requirement should be performed only after extrapolation of the linear part at higher light intensities of the quantum requirement curves to "0" light intensity.

  2. 19 CFR 200.735-123 - Effect of employees' and special Government employees' statements on other requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 3 2014-04-01 2014-04-01 false Effect of employees' and special Government employees' statements on other requirements. 200.735-123 Section 200.735-123 Customs Duties UNITED STATES... permit him or any other person to participate in a matter which his or the other person's participation...

  3. 19 CFR 200.735-123 - Effect of employees' and special Government employees' statements on other requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Effect of employees' and special Government employees' statements on other requirements. 200.735-123 Section 200.735-123 Customs Duties UNITED STATES... permit him or any other person to participate in a matter which his or the other person's participation...

  4. 19 CFR 200.735-123 - Effect of employees' and special Government employees' statements on other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Effect of employees' and special Government employees' statements on other requirements. 200.735-123 Section 200.735-123 Customs Duties UNITED STATES... permit him or any other person to participate in a matter which his or the other person's participation...

  5. 19 CFR 200.735-123 - Effect of employees' and special Government employees' statements on other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Effect of employees' and special Government employees' statements on other requirements. 200.735-123 Section 200.735-123 Customs Duties UNITED STATES... permit him or any other person to participate in a matter which his or the other person's participation...

  6. 19 CFR 200.735-123 - Effect of employees' and special Government employees' statements on other requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 3 2012-04-01 2012-04-01 false Effect of employees' and special Government employees' statements on other requirements. 200.735-123 Section 200.735-123 Customs Duties UNITED STATES... permit him or any other person to participate in a matter which his or the other person's participation...

  7. The Competencies Required for Effective Performance in a University e-Learning Environment

    ERIC Educational Resources Information Center

    Parkes, Mitchell; Reading, Christine; Stein, Sarah

    2013-01-01

    The aim of this study was to identify and rate the importance of the competencies required by students for effective performance in a university e-learning environment mediated by a learning management system. Two expert panels identified 58 e-learning competencies considered to be essential for e-learning. Of these competencies, 22 were related…

  8. 40 CFR 5.535 - Effect of state or local law or other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 5.535 Effect of... other requirement that imposes prohibitions or limits upon employment of members of one sex that are not...

  9. Development of an Effective School-Based Financial Management Profile in Malaysia: The Delphi Method Application

    ERIC Educational Resources Information Center

    Radzi, Norfariza Mohd; Ghani, Muhammad Faizal A.; Siraj, Saedah

    2015-01-01

    The agenda for national development requires a persistent improvement in education as a tool for creating knowledgeable human capital, highly skilled labour, a high technology society and ultimately a highly civilized nation for the future challenging world. It requires considerable financial and technical investment as well as effective and…

  10. 43 CFR 46.100 - Federal action subject to the procedural requirements of NEPA.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... action is subject to the procedural requirements of NEPA if it would cause effects on the human... funding or approval are necessary to implement it. If Federal funding is provided with no Federal agency... decision on one or more alternative means of accomplishing that goal; and (2) The effects of the proposed...

  11. 43 CFR 46.100 - Federal action subject to the procedural requirements of NEPA.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... action is subject to the procedural requirements of NEPA if it would cause effects on the human... funding or approval are necessary to implement it. If Federal funding is provided with no Federal agency... decision on one or more alternative means of accomplishing that goal; and (2) The effects of the proposed...

  12. 43 CFR 46.100 - Federal action subject to the procedural requirements of NEPA.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... action is subject to the procedural requirements of NEPA if it would cause effects on the human... funding or approval are necessary to implement it. If Federal funding is provided with no Federal agency... decision on one or more alternative means of accomplishing that goal; and (2) The effects of the proposed...

  13. 43 CFR 46.100 - Federal action subject to the procedural requirements of NEPA.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... action is subject to the procedural requirements of NEPA if it would cause effects on the human... funding or approval are necessary to implement it. If Federal funding is provided with no Federal agency... decision on one or more alternative means of accomplishing that goal; and (2) The effects of the proposed...

  14. 43 CFR 46.100 - Federal action subject to the procedural requirements of NEPA.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... action is subject to the procedural requirements of NEPA if it would cause effects on the human... funding or approval are necessary to implement it. If Federal funding is provided with no Federal agency... decision on one or more alternative means of accomplishing that goal; and (2) The effects of the proposed...

  15. The Effects of Specifying Job Requirements and Using Explicit Warnings to Decrease Sex Discrimination in Employment Interviews.

    ERIC Educational Resources Information Center

    Siegfried, William D.

    1982-01-01

    To determine effectiveness of instructions designed to reduce sex discrimination in employment interviews, students were asked to rate resumes for a male and a female applicant under different instructional conditions. Results suggested that: legal warnings may bias ratings in favor of male applicants; and specifying job requirements reduces…

  16. Causality and Causal Inference in Social Work: Quantitative and Qualitative Perspectives

    ERIC Educational Resources Information Center

    Palinkas, Lawrence A.

    2014-01-01

    Achieving the goals of social work requires matching a specific solution to a specific problem. Understanding why the problem exists and why the solution should work requires a consideration of cause and effect. However, it is unclear whether it is desirable for social workers to identify cause and effect, whether it is possible for social workers…

  17. 17 CFR 240.17a-2 - Recordkeeping requirements relating to stabilizing activities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... (a) Scope of section. This section shall apply to any person who effects any purchase of a security... engages in, “stabilizing,” as defined in § 242.100 of this chapter, the price of any security; or effects... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Recordkeeping requirements...

  18. 76 FR 47085 - Effective Date of Requirement for Premarket Approval for a Pacemaker Programmer

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    .... FDA-2011-N-0526] Effective Date of Requirement for Premarket Approval for a Pacemaker Programmer... programmers. The agency is also summarizing its proposed findings regarding the degree of risk of illness or.... Background--Regulatory Authorities The Federal Food, Drug, and Cosmetic Act (the FD&C Act), as amended by the...

  19. Advance Planning Briefing for Industry. Technology Requirements Briefings

    DTIC Science & Technology

    2009-02-17

    procedure drills through complex multiplayer interactions representative of a motorcade under heavy attack. The tool shall provide a first-person...Integrated Munitions Effect Assessment IMI Interactive Multimedia Instruction IP Internet Protocol IPE Intelligence Preparation of the Environment IR...CTTSO Programs and Mission Areas/Subgroups 13 Requirement Descriptions Blast Effects and Mitigation (BX) 16 Chemical, Biological, Radiological, and

  20. A Study of the Comparative Effectiveness of Zoology Prerequisites at Slippery Rock State College.

    ERIC Educational Resources Information Center

    Morrison, William Sechler

    This study compared the effectiveness of three sequences of prerequisite courses required before taking zoology. Sequence 1 prerequisite courses consisted of general biology and human biology; Sequence 2 consisted of general biology; and Sequence 3 required cell biology. Zoology students in the spring of 1972 were pretest and a posttest. The mean…

  1. 77 FR 39924 - Effective Date of Requirement for Premarket Approval for Cardiovascular Permanent Pacemaker...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-06

    .... FDA-2011-N-0505] Effective Date of Requirement for Premarket Approval for Cardiovascular Permanent... application (PMA) or a notice of completion of a product development protocol (PDP) for the cardiovascular...) of the FD&C Act of a PMA or notice of completion of a PDP for the cardiovascular permanent pacemaker...

  2. 28 CFR 91.4 - Truth in Sentencing Incentive Grants.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of Part 1 violent crimes reported by such state to the Federal Bureau of Investigation for 1993 bears... demonstrate that the state(s)— (1) Has in effect laws which require that persons convicted of violent crimes... effect at the time of application laws requiring that a person who is convicted of a violent crime shall...

  3. Forbearance for fluoxetine: do monoaminergic antidepressants require a number of years to reach maximum therapeutic effect in humans?

    PubMed

    Fitzgerald, Paul J

    2014-07-01

    It is of high clinical interest to better understand the timecourse through which psychiatric drugs produce their beneficial effects. While a rough estimate of the time lag between initiating monoaminergic antidepressant therapy and the onset of therapeutic effect in depressed subjects is two weeks, much less is known about when these drugs reach maximum effect. This paper briefly examines studies that directly address this question through long-term antidepressant administration to humans, while also putting forth a simple theoretical approach for estimating the time required for monoaminergic antidepressants to reach maximum therapeutic effect in humans. The theory invokes a comparison between speed of antidepressant drug response in humans and in rodents, focusing on the apparently greater speed in rodents. The principal argument is one of proportions, comparing earliest effects of these drugs in rodents and humans, versus their time to reach maximum effect in these organisms. If the proportionality hypothesis is even coarsely accurate, then applying these values or to some degree their ranges to the hypothesis, may suggest that monoaminergic antidepressants require a number of years to reach maximum effect in humans, at least in some individuals.

  4. Efficient calculation of the polarizability: a simplified effective-energy technique

    NASA Astrophysics Data System (ADS)

    Berger, J. A.; Reining, L.; Sottile, F.

    2012-09-01

    In a recent publication [J.A. Berger, L. Reining, F. Sottile, Phys. Rev. B 82, 041103(R) (2010)] we introduced the effective-energy technique to calculate in an accurate and numerically efficient manner the GW self-energy as well as the polarizability, which is required to evaluate the screened Coulomb interaction W. In this work we show that the effective-energy technique can be used to further simplify the expression for the polarizability without a significant loss of accuracy. In contrast to standard sum-over-state methods where huge summations over empty states are required, our approach only requires summations over occupied states. The three simplest approximations we obtain for the polarizability are explicit functionals of an independent- or quasi-particle one-body reduced density matrix. We provide evidence of the numerical accuracy of this simplified effective-energy technique as well as an analysis of our method.

  5. Cognitive dissonance in children: justification of effort or contrast?

    PubMed

    Alessandri, Jérôme; Darcheville, Jean-Claude; Zentall, Thomas R

    2008-06-01

    Justification of effort is a form of cognitive dissonance in which the subjective value of an outcome is directly related to the effort that went into obtaining it. However, it is likely that in social contexts (such as the requirements for joining a group) an inference can be made (perhaps incorrectly) that an outcome that requires greater effort to obtain in fact has greater value. Here we present evidence that a cognitive dissonance effect can be found in children under conditions that offer better control for the social value of the outcome. This effect is quite similar to contrast effects that recently have been studied in animals. We suggest that contrast between the effort required to obtain the outcome and the outcome itself provides a more parsimonious account of this phenomenon and perhaps other related cognitive dissonance phenomena as well. Research will be needed to identify cognitive dissonance processes that are different from contrast effects of this kind.

  6. The effect of ordinances requiring smoke-free restaurants and bars on revenues: a follow-up.

    PubMed Central

    Glantz, S A; Smith, L R

    1997-01-01

    OBJECTIVES: The purpose of this study was to extend an earlier evaluation of the economic effects of ordinances requiring smoke-free restaurants and bars. METHODS: Sales tax data for 15 cities with smoke-free restaurant ordinances, 5 cities and 2 counties with smoke-free bar ordinances, and matched comparison locations were analyzed by multiple regression, including time and a dummy variable for the ordinance. RESULTS: Ordinances had no significant effect on the fraction of total retail sales that went to eating and drinking places or on the ratio between sales in communities with ordinances and sales in comparison communities. Ordinances requiring smoke-free bars had no significant effect on the fraction of revenues going to eating and drinking places that serve all types of liquor. CONCLUSIONS: Smoke-free ordinances do not adversely affect either restaurant or bar sales. PMID:9357356

  7. 78 FR 24107 - Version 5 Critical Infrastructure Protection Reliability Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... native applications or print-to-PDF format and not a scanned format. Mail/Hand Delivery: Those unable to... criteria that characterize their impact for the application of cyber security requirements commensurate... recognition. Requirement R2 requires testing to verify response plan effectiveness and consistent application...

  8. 32 CFR 187.6 - Information requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Information requirements. 187.6 Section 187.6 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE ENVIRONMENT ENVIRONMENTAL EFFECTS ABROAD OF MAJOR DEPARTMENT OF DEFENSE ACTIONS § 187.6 Information requirements. The documents to be...

  9. 14 CFR 291.22 - Aircraft accident liability insurance requirement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Aircraft accident liability insurance... for All-Cargo Air Transportation § 291.22 Aircraft accident liability insurance requirement. No air... and maintains in effect aircraft accident liability coverage that meets the requirements of part 205...

  10. 14 CFR 137.19 - Certification requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... economic poisons, that applicant is not required to demonstrate the knowledge required in paragraphs (e)(1... starting operations, including survey of the area to be worked. (ii) Safe handling of economic poisons and the proper disposal of used containers for those poisons. (iii) The general effects of economic...

  11. 14 CFR 137.19 - Certification requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... economic poisons, that applicant is not required to demonstrate the knowledge required in paragraphs (e)(1... starting operations, including survey of the area to be worked. (ii) Safe handling of economic poisons and the proper disposal of used containers for those poisons. (iii) The general effects of economic...

  12. 14 CFR 137.19 - Certification requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... economic poisons, that applicant is not required to demonstrate the knowledge required in paragraphs (e)(1... starting operations, including survey of the area to be worked. (ii) Safe handling of economic poisons and the proper disposal of used containers for those poisons. (iii) The general effects of economic...

  13. 14 CFR 137.19 - Certification requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... economic poisons, that applicant is not required to demonstrate the knowledge required in paragraphs (e)(1... starting operations, including survey of the area to be worked. (ii) Safe handling of economic poisons and the proper disposal of used containers for those poisons. (iii) The general effects of economic...

  14. 76 FR 3604 - Information Collection; Qualified Products List for Engine Driven Pumps

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ... levels. 2. Reliability and endurance requirements. These requirements include a 100-hour endurance test... evaluated to meet specific requirements related to safety, effectiveness, efficiency, and reliability of the... of the collection of information, including the validity of the methodology and assumptions used; (3...

  15. 75 FR 7370 - Closed Captioning of Video Programming; Closed Captioning Requirements for Digital Television...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... 08-255] Closed Captioning of Video Programming; Closed Captioning Requirements for Digital Television... Captioning of Video Programming; Closed Captioning Requirements for Digital Television Receivers, Declaratory... 1594, January 13, 2009, is effective February 19, 2010. Video programming distributors must comply with...

  16. 7 CFR 273.12 - Reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... requiring Social Security numbers, the routine uses for Social Security numbers, and the effect of not... paragraph (c) of this section; (x) If the form requests Social Security numbers, include a statement of the State agency's authority to require Social Security numbers (including the statutory citation, the title...

  17. 77 FR 61550 - Airworthiness Directives; The Boeing Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... inspection required by AD 2003-14-06 only terminates the external eddy current inspections required by..., which should not terminate the detailed or eddy current inspection, as specified. We find that... terminating action ``before the effective date of this AD'' terminates the eddy current inspections required...

  18. Building a Narrative Based Requirements Engineering Mediation Model

    NASA Astrophysics Data System (ADS)

    Ma, Nan; Hall, Tracy; Barker, Trevor

    This paper presents a narrative-based Requirements Engineering (RE) mediation model to help RE practitioners to effectively identify, define, and resolve conflicts of interest, goals, and requirements. Within the SPI community, there is a common belief that social, human, and organizational issues significantly impact on the effectiveness of software process improvement in general and the requirements engineering process in particularl. Conflicts among different stakeholders are an important human and social issue that need more research attention in the SPI and RE community. By drawing on the conflict resolution literature and IS literature, we argue that conflict resolution in RE is a mediated process, in which a requirements engineer can act as a mediator among different stakeholders. To address socio-psychological aspects of conflict in RE and SPI, Winslade and Monk (2000)'s narrative mediation model is introduced, justified, and translated into the context of RE.

  19. Technology Requirements For a Square-Meter, Arcsecond-Resolution Telescope for X-Rays: The SMART-X Mission

    NASA Technical Reports Server (NTRS)

    Schwartz, Daniel A.; Allured, Ryan; Bookbinder, Jay; Cotroneo, Vincenzo; Forman, William; Freeman, Mark; McMuldroch, Stuart; Reid, Paul; Tananbaum, Harvey; Vikhlinin, Alexey; hide

    2014-01-01

    Addressing the astrophysical problems of the 2020's requires sub-arcsecond x-ray imaging with square meter effective area. Such requirements can be derived, for example, by considering deep x-ray surveys to find the young black holes in the early universe (large redshifts) which will grow into the first supermassive black holes. We have envisioned a mission based on adjustable x-ray optics technology, in order to achieve the required reduction of mass to collecting area for the mirrors. We are pursuing technology which effects this adjustment via thin film piezoelectric "cells" deposited directly on the non-reflecting sides of thin, slumped glass. While SMARTX will also incorporate state-of-the-art x-ray cameras, the remaining spacecraft systems have no more stringent requirements than those which are well understood and proven on the current Chandra X-ray Observatory.

  20. Short-term effect of red wine (consumed during meals) on insulin requirement and glucose tolerance in diabetic patients.

    PubMed

    Gin, H; Morlat, P; Ragnaud, J M; Aubertin, J

    1992-04-01

    To determine the effect of wine on insulin requirement or glucose tolerance. Five men with insulin-treated diabetes and 10 men with non-insulin-treated diabetes ate the same lunch with the same volume of either water or red wine (2 glasses). Insulin requirement was determined with an artificial pancreas (Biostator). Glucose tolerance was evaluated from the postprandial glycemic level. There was no significant difference in insulin requirement determined with an artificial pancreas in the insulin-treated patients after the two meals (31.5 +/- 4.21 U with water and 31.8 +/- 4.3 U with wine). Glucose tolerance in the non-insulin-treated patients was lower after the meal with wine. Moderate prandial wine consumption has no adverse effect on the glycemic control of diabetic patients. Thus, it appears unnecessary to proscribe the consumption of red wine in moderation with meals to diabetic patients. Wine contains tannins and phytates that can explain its action.

  1. Dimension- and space-based intertrial effects in visual pop-out search: modulation by task demands for focal-attentional processing.

    PubMed

    Krummenacher, Joseph; Müller, Hermann J; Zehetleitner, Michael; Geyer, Thomas

    2009-03-01

    Two experiments compared reaction times (RTs) in visual search for singleton feature targets defined, variably across trials, in either the color or the orientation dimension. Experiment 1 required observers to simply discern target presence versus absence (simple-detection task); Experiment 2 required them to respond to a detection-irrelevant form attribute of the target (compound-search task). Experiment 1 revealed a marked dimensional intertrial effect of 34 ms for an target defined in a changed versus a repeated dimension, and an intertrial target distance effect, with an 4-ms increase in RTs (per unit of distance) as the separation of the current relative to the preceding target increased. Conversely, in Experiment 2, the dimension change effect was markedly reduced (11 ms), while the intertrial target distance effect was markedly increased (11 ms per unit of distance). The results suggest that dimension change/repetition effects are modulated by the amount of attentional focusing required by the task, with space-based attention altering the integration of dimension-specific feature contrast signals at the level of the overall-saliency map.

  2. Relative Utility of Selected Software Requirement Metrics

    DTIC Science & Technology

    1991-12-01

    testing . They can also help in deciding if and how to use complexity reduction techniques. In summary, requirement metrics can be useful because they...answer items in a test instrument. In order to differentiate between misinterpretation and comprehension, the measurement technique must be able to...effectively test a requirement, it is verifiable. Ramamoorthy and others have proposed requirements complexity metrics that can be used to infer the

  3. Effect of Age on Energy Requirement for Maintenance and Growth of Dorper and Hu Crossbred F1 Ewes Weighing 20 to 50 kg

    PubMed Central

    Nie, H. T.; Wan, Y. J.; You, J. H.; Wang, Z. Y.; Lan, S.; Fan, Y. X.; Wang, F.

    2015-01-01

    This research aimed to define the energy requirement of Dorper and Hu Hybrid F1 ewes 20 to 50 kg of body weight, furthermore to study energy requirement changes with age and evaluate the effect of age on energy requirement parameters. In comparative slaughter trial, thirty animals were divided into three dry matter intake treatments (ad libitum, n = 18; low restricted, n = 6; high restricted, n = 6), and were all slaughtered as baseline, intermediate, and final slaughter groups, to calculate body chemical components and energy retained. In digestibility trial, twelve ewes were housed in individual metabolic cages and randomly assigned to three feeding treatments in accordance with the design of a comparative slaughter trial, to evaluate dietary energetic values at different feed intake levels. The combined data indicated that, with increasing age, the net energy requirement for maintenance (NEm) decreased from 260.62±13.21 to 250.61±11.79 kJ/kg0.75 of shrunk body weight (SBW)/d, and metabolizable energy requirement for maintenance (MEm) decreased from 401.99±20.31 to 371.23±17.47 kJ/kg0.75 of SBW/d. Partial efficiency of ME utilization for maintenance (km, 0.65 vs 0.68) and growth (kg, 0.42 vs 0.41) did not differ (p>0.05) due to age; At the similar condition of average daily gain, net energy requirements for growth (NEg) and metabolizable energy requirements for growth (MEg) for ewes during late fattening period were 23% and 25% greater than corresponding values of ewes during early fattening period. In conclusion, the effect of age upon energy requirement parameters in the present study were similar in tendency with previous recommendations, values of energy requirement for growth (NEg and MEg) for Dorper and Hu crossbred female lambs ranged between the NRC (2007) recommendation for early and later maturating growing sheep. PMID:26104522

  4. Data Collection and Administration Procedures for the Job Performance Measurement System

    DTIC Science & Technology

    1992-10-01

    acceptable to the MAJCC4s and would allow data collection to proceed smoothly with effective use of time and resources. Table 2 lists the number of bases...WTPT, but this was not required. Previous exposure to the JPM project was also beneficial, though not required. Finally, to ensure an effective line of...PDCIKR 1. Provide team leadership to facilitate effective operation and the collection of quality data. 2. Serve as the liaison between team and AFHRL

  5. 40 CFR 6.209 - Filing requirements for EPA EISs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Filing requirements for EPA EISs. 6.209... IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT AND ASSESSING THE ENVIRONMENTAL EFFECTS ABROAD OF EPA ACTIONS EPA's NEPA Environmental Review Procedures § 6.209 Filing requirements for EPA EISs. (a) The...

  6. 7 CFR 319.40-8 - Processing at facilities operating under compliance agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... compliance agreement shall specify the requirements necessary to prevent spread of plant pests from the facility, requirements to ensure the processing method effectively destroys plant pests, and the requirements for the application of chemical materials in accordance with part 305 of this chapter. The...

  7. 7 CFR 319.40-8 - Processing at facilities operating under compliance agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... compliance agreement shall specify the requirements necessary to prevent spread of plant pests from the facility, requirements to ensure the processing method effectively destroys plant pests, and the requirements for the application of chemical materials in accordance with part 305 of this chapter. The...

  8. Requirements Analysis is Key to Realizing Increased Value from Remote Sensing

    NASA Technical Reports Server (NTRS)

    Ryan, Robert; Alexander, Timothy M.

    2001-01-01

    This note explores requirements analysis - one of the critical and very often overlooked activities that enable satellites to measure what is important and to translate observations into effective and affordable information. Recent experience at the Stennis Space Center is used to illuminate some approaches for improving requirements practice.

  9. Saint Lawrence Seaway Navigation-Aid System Study : Volume III - Appendix C - User's Manual and Documentation of the Ship Maneuvering Requirements Computer Program

    DOT National Transportation Integrated Search

    1978-09-01

    The requirements for a navigation guidance system which will effect an increase in the ship processing capacity of the Saint Lawrence Seaway (Lake Ontario to Montreal, Quebec) are developed. The requirements include a specification of system position...

  10. Orbital construction demonstration study. Volume 2: Technical

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The following items are discussed in reference to OCDA requirements; (1) flight mechanics and control, (2) effects of sun angle, (3) disturbance torques, (4) control system requirements, (5) OCDA orbit decay profile, and (6) aerodynamic drag forces. Structural design requirements are also given as well as basic design definition.

  11. 42 CFR 84.87 - Compressed gas filters; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Compressed gas filters; minimum requirements. 84.87...-Contained Breathing Apparatus § 84.87 Compressed gas filters; minimum requirements. All self-contained breathing apparatus using compressed gas shall have a filter downstream of the gas source to effectively...

  12. 42 CFR 84.87 - Compressed gas filters; minimum requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Compressed gas filters; minimum requirements. 84.87...-Contained Breathing Apparatus § 84.87 Compressed gas filters; minimum requirements. All self-contained breathing apparatus using compressed gas shall have a filter downstream of the gas source to effectively...

  13. 42 CFR 84.87 - Compressed gas filters; minimum requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Compressed gas filters; minimum requirements. 84.87...-Contained Breathing Apparatus § 84.87 Compressed gas filters; minimum requirements. All self-contained breathing apparatus using compressed gas shall have a filter downstream of the gas source to effectively...

  14. 42 CFR 84.87 - Compressed gas filters; minimum requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Compressed gas filters; minimum requirements. 84.87...-Contained Breathing Apparatus § 84.87 Compressed gas filters; minimum requirements. All self-contained breathing apparatus using compressed gas shall have a filter downstream of the gas source to effectively...

  15. 77 FR 1935 - Information Collection Being Reviewed by the Federal Communications Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-12

    ...-0645. Title: Sections 17.4, 17.48 and 17.49, Antenna Structure Registration Requirements. Form Number... uniform registration process as well as safe and effective lighting procedures for owners of antenna structures. Section 17.4 requires the owner of any proposed or existing antenna structure that requires...

  16. 40 CFR 158.2172 - Experimental use permit microbial pesticides residue data requirements table.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... results of testing: i. Indicate the potential to cause adverse human health effects or the product... pesticides residue data requirements table. 158.2172 Section 158.2172 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Microbial Pesticides § 158...

  17. 40 CFR 158.2172 - Experimental use permit microbial pesticides residue data requirements table.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... results of testing: i. Indicate the potential to cause adverse human health effects or the product... pesticides residue data requirements table. 158.2172 Section 158.2172 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Microbial Pesticides § 158...

  18. 40 CFR 158.2172 - Experimental use permit microbial pesticides residue data requirements table.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... results of testing: i. Indicate the potential to cause adverse human health effects or the product... pesticides residue data requirements table. 158.2172 Section 158.2172 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Microbial Pesticides § 158...

  19. 40 CFR 158.2172 - Experimental use permit microbial pesticides residue data requirements table.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... results of testing: i. Indicate the potential to cause adverse human health effects or the product... pesticides residue data requirements table. 158.2172 Section 158.2172 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Microbial Pesticides § 158...

  20. 40 CFR 158.2172 - Experimental use permit microbial pesticides residue data requirements table.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... results of testing: i. Indicate the potential to cause adverse human health effects or the product... pesticides residue data requirements table. 158.2172 Section 158.2172 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Microbial Pesticides § 158...

  1. 76 FR 1213 - Core Principles and Other Requirements for Swap Execution Facilities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... Part II Commodity Futures Trading Commission 17 CFR Part 37 Core Principles and Other Requirements... RIN Number 3038-AD18 Core Principles and Other Requirements for Swap Execution Facilities AGENCY... Compliance With the Core Principles III. Effective Date and Transition Period IV. Related Matters A...

  2. 42 CFR 84.87 - Compressed gas filters; minimum requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Compressed gas filters; minimum requirements. 84.87...-Contained Breathing Apparatus § 84.87 Compressed gas filters; minimum requirements. All self-contained breathing apparatus using compressed gas shall have a filter downstream of the gas source to effectively...

  3. 45 CFR 98.40 - Compliance with applicable State and local regulatory requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Lead Agency and Provider... shall: (1) Certify that they have in effect licensing requirements applicable to child care services... requirements on child care providers of services for which assistance is provided under the CCDF than the...

  4. 45 CFR 98.40 - Compliance with applicable State and local regulatory requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Lead Agency and Provider... shall: (1) Certify that they have in effect licensing requirements applicable to child care services... requirements on child care providers of services for which assistance is provided under the CCDF than the...

  5. 45 CFR 98.40 - Compliance with applicable State and local regulatory requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Lead Agency and Provider... shall: (1) Certify that they have in effect licensing requirements applicable to child care services... requirements on child care providers of services for which assistance is provided under the CCDF than the...

  6. 45 CFR 98.40 - Compliance with applicable State and local regulatory requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Lead Agency and Provider... shall: (1) Certify that they have in effect licensing requirements applicable to child care services... requirements on child care providers of services for which assistance is provided under the CCDF than the...

  7. 45 CFR 98.40 - Compliance with applicable State and local regulatory requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Lead Agency and Provider... shall: (1) Certify that they have in effect licensing requirements applicable to child care services... requirements on child care providers of services for which assistance is provided under the CCDF than the...

  8. 33 CFR 149.641 - What are the structural fire protection requirements for accommodation spaces and modules?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... protection requirements for accommodation spaces and modules? 149.641 Section 149.641 Navigation and... the structural fire protection requirements for accommodation spaces and modules? (a) Accommodation spaces and modules must be designed, located, and constructed so as to minimize the effects of flame...

  9. 77 FR 72993 - Atlantic Highly Migratory Species; Electronic Dealer Reporting Requirements; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-07

    .... 110208116-2233-02] RIN 0648-BA75 Atlantic Highly Migratory Species; Electronic Dealer Reporting Requirements... rule not yet in effect. It contains a correction to the final regulations regarding electronic dealer... things, require electronic dealer reporting for all federal Atlantic HMS dealers. On August 8, 2012 (77...

  10. Improving Preservice Teachers' Self-Efficacy through Service Learning: Lessons Learned

    ERIC Educational Resources Information Center

    Bernadowski, Carianne; Perry, Ronald; Del Greco, Robert

    2013-01-01

    University students have been barraged with service learning opportunities both as course required and as volunteer opportunities in recent years. Currently, many universities now require students to participate in engaged learning as a graduation requirement. Situated in Bandura's theory of self-efficacy, this study examines the effects service…

  11. 12 CFR 611.1122 - Requirements for mergers or consolidations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Requirements for mergers or consolidations. 611... Mergers, Consolidations, and Charter Amendments of Associations § 611.1122 Requirements for mergers or... association, which retains its charter and bylaws (except as amended to effect the merger proposal). A...

  12. Harnessing the Power or Narratives to Understand User Requirements

    ERIC Educational Resources Information Center

    Hvalshagen, Merete

    2011-01-01

    It is estimated that $150 billion is wasted yearly on information and communications technology failures in the US. The most common reason for failure is deficiencies in the specified requirements. IS researchers and IS practitioners are therefore continuously exploring methods for effectively analyzing and capturing the user requirements. One…

  13. 77 FR 51459 - Suspension of End-Use Certificate Program Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    ... indefinitely the Farm Service Agency (FSA) regulation requiring end-use certificates and tracking of wheat... Canadian produced wheat are no longer required to provide FSA end-use certificates or consumption and resale reports on wheat produced in Canada. DATES: Effective August 31, 2012. FOR FURTHER INFORMATION...

  14. 7 CFR 273.12 - Requirements for change reporting households.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... requiring Social Security numbers, the routine uses for Social Security numbers, and the effect of not... paragraph (c) of this section; (x) If the form requests Social Security numbers, include a statement of the State agency's authority to require Social Security numbers (including the statutory citation, the title...

  15. 7 CFR 273.12 - Requirements for change reporting households.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... requiring Social Security numbers, the routine uses for Social Security numbers, and the effect of not... paragraph (c) of this section; (x) If the form requests Social Security numbers, include a statement of the State agency's authority to require Social Security numbers (including the statutory citation, the title...

  16. Data Requirements for Pesticide Registration

    EPA Pesticide Factsheets

    In evaluating a pesticide registration application, we assess a wide variety of potential human health and environmental effects associated with use of the product. Learn about these data requirements.

  17. 78 FR 60975 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... certain notices to the Exchange. Under NYSE Arca Equities Rule 5.3(i)(1), each listed company is required... Exchange at least 10 business days prior to the record date. The same notice requirement also applies to an...-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule...

  18. Why Pigeons Say What They Do: Reinforcer Magnitude and Response Requirement Effects on Say Responding in Say-Do Correspondence

    ERIC Educational Resources Information Center

    da Silva, Stephanie P.; Lattal, Kennon A.

    2010-01-01

    The effects of reinforcer magnitude and response requirement on pigeons' say choices in an experimental homologue of human say-do correspondence were assessed in two experiments. The procedure was similar to a conditional discrimination procedure except the pigeons chose both a sample stimulus (the say component) and a comparison stimulus that…

  19. 20 CFR 655.1112 - Element II-What does “no adverse effect on wages and working conditions” mean?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... What Requirements Must a Facility Meet to Employ H-1C Nonimmigrant Workers as Registered Nurses? § 655... affect the wages and working conditions of registered nurses similarly employed.” (b) For purposes of...-1C nurses is not authorized. (c) Wages. To meet the requirement of no adverse effect on wages, the...

  20. 20 CFR 655.1112 - Element II-What does “no adverse effect on wages and working conditions” mean?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... What Requirements Must a Facility Meet to Employ H-1C Nonimmigrant Workers as Registered Nurses? § 655... affect the wages and working conditions of registered nurses similarly employed.” (b) For purposes of...-1C nurses is not authorized. (c) Wages. To meet the requirement of no adverse effect on wages, the...

  1. Effective Counseling, Empowered Borrowers: An Evidence-Based Policy Agenda for Informed Student Loan Borrowing and Repayment. Research Report

    ERIC Educational Resources Information Center

    Fernandez, Chris

    2016-01-01

    To manage their loans effectively, U.S. postsecondary student loan borrowers must make a variety of important decisions that require significant knowledge and financial skills and entail considerable risk. Federal law requires colleges to provide student loan counseling to their federal student loan borrowers, but there is significant room for…

  2. 10 CFR 1040.64 - Effect of State or local law or other requirements and effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of DOE which impose requirements designed to prohibit discrimination against individuals on the grounds of race, color, national origin, sex, age or handicap under any program or activity to which this... discrimination on the ground of race, color, national origin, sex, age, or handicap in any program or activity to...

  3. 15 CFR 8a.535 - Effect of state or local law or other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Effect of state or local law or other requirements. 8a.535 Section 8a.535 Commerce and Foreign Trade Office of the Secretary of Commerce... are not imposed upon members of the other sex. (b) Benefits. A recipient that provides any...

  4. Drude Conductivity of Dirac Fermions in Graphene

    DTIC Science & Technology

    2010-01-01

    interband transitions, as required by the sum rule. Our surprising observation indicates that many-body effects and Dirac fermion-impurity interactions...reduction of free electron oscillator strength is corroborated by corresponding changes in graphene interband transitions, as required by the sum...dimensions. Researchers have demonstrated in graphene exotic Dirac fermion phenomena ranging from anomalous quantum Hall effects 1,2 to Klein tunneling 3 in

  5. Effect of toxic threat nerve agents on anesthetic requirements of representative pr-anesthetic medicants and inhalant and parenteral general anesthetic in the cat. Annual report, 15 July 1985-14 July 1986

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Webb, A.I.

    1986-07-30

    The effect of soman on anesthetic requirements of halothane and isoflurane was studied before and after administration of acepromazine maleate (0.2 mg/kg). Insufficient data has been obtained to date to draw conclusions on any possible drug interactions.

  6. Environmental Quality: Environmental Protection and Enhancement

    DTIC Science & Technology

    2002-01-17

    have an adverse effect on human health . These regulations are federally enforceable. Primacy states may have more stringent requirements. Primary...includes TT requirements for filtered and unfiltered systems that are specifically designed to protect against the adverse health effects of exposure to...MTBE (20) Alachlor ESA (36) Lead- 210 (9) Nitrobenzene (21) 1,2-diphenylhydrazine (37) Polonium - 210 (10) Terbacil (22) Diazinon (11) Acetochlor (23

  7. The Relationship between Processing and Storage in Working Memory Span: Not Two Sides of the Same Coin

    ERIC Educational Resources Information Center

    Maehara, Yukio; Saito, Satoru

    2007-01-01

    In working memory (WM) span tests, participants maintain memory items while performing processing tasks. In this study, we examined the impact of task processing requirements on memory-storage activities, looking at the stimulus order effect and the impact of storage requirements on processing activities, testing the processing time effect in WM…

  8. 13 CFR 113.535 - Effect of state or local law or other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Effect of state or local law or other requirements. 113.535 Section 113.535 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... obligation to comply with §§ 113.500 through 113.550 is not obviated or alleviated by the existence of any...

  9. 20 CFR 416.1725 - Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism. 416.1725 Section 416.1725 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Referral of Persons Eligible for Supplemental Security...

  10. Adequacy of Material Resources Required for Effective Implementation of Upper Basic Education Business Studies Curriculum in Nigeria

    ERIC Educational Resources Information Center

    Okoli, B. E.; Okorie, Ogbonnaya

    2015-01-01

    This work is a descriptive survey of the adequacy of the material resources required for effective implementation of upper basic education business studies curriculum in Ebonyi State. Two research questions and two hypotheses guided the study. The entire population of two hundred and forty-one (241) business studies teachers were used for the…

  11. Effect of initial planting spacing on wood properties of unthinned loblolly pine at age 21

    Treesearch

    Alexander III Clark; Lewis Jordan; Laurie Schimleck; Richard F. Daniels

    2008-01-01

    Young, fast growing, intensively managed plantation loblolly pine (Pinus taeda L.) contains a large proportion of juvenile wood that may not have the stiffness required to meet the design requirements for southern pine dimension lumber. An unthinned loblolly pine spacing study was sampled to determine the effect of initial spacing on wood stiffness,...

  12. NASA Manned Launch Vehicle Lightning Protection Development

    NASA Technical Reports Server (NTRS)

    McCollum, Matthew B.; Jones, Steven R.; Mack, Jonathan D.

    2009-01-01

    Historically, the National Aeronautics and Space Administration (NASA) relied heavily on lightning avoidance to protect launch vehicles and crew from lightning effects. As NASA transitions from the Space Shuttle to the new Constellation family of launch vehicles and spacecraft, NASA engineers are imposing design and construction standards on the spacecraft and launch vehicles to withstand both the direct and indirect effects of lightning. A review of current Space Shuttle lightning constraints and protection methodology will be presented, as well as a historical review of Space Shuttle lightning requirements and design. The Space Shuttle lightning requirements document, NSTS 07636, Lightning Protection, Test and Analysis Requirements, (originally published as document number JSC 07636, Lightning Protection Criteria Document) was developed in response to the Apollo 12 lightning event and other experiences with NASA and the Department of Defense launch vehicles. This document defined the lightning environment, vehicle protection requirements, and design guidelines for meeting the requirements. The criteria developed in JSC 07636 were a precursor to the Society of Automotive Engineers (SAE) lightning standards. These SAE standards, along with Radio Technical Commission for Aeronautics (RTCA) DO-160, Environmental Conditions and Test Procedures for Airborne Equipment, are the basis for the current Constellation lightning design requirements. The development and derivation of these requirements will be presented. As budget and schedule constraints hampered lightning protection design and verification efforts, the Space Shuttle elements waived the design requirements and relied on lightning avoidance in the form of launch commit criteria (LCC) constraints and a catenary wire system for lightning protection at the launch pads. A better understanding of the lightning environment has highlighted the vulnerability of the protection schemes and associated risk to the vehicle, which has resulted in lost launch opportunities and increased expenditures in manpower to assess Space Shuttle vehicle health and safety after lightning events at the launch pad. Because of high-percentage launch availability and long-term on-pad requirements, LCC constraints are no longer considered feasible. The Constellation vehicles must be designed to withstand direct and indirect effects of lightning. A review of the vehicle design and potential concerns will be presented as well as the new catenary lightning protection system for the launch pad. This system is required to protect the Constellation vehicles during launch processing when vehicle lightning effects protection might be compromised by such items as umbilical connections and open access hatches.

  13. Moving beyond the current state of the internet

    NASA Astrophysics Data System (ADS)

    Chen, Edward S.; Davison, Daniel B.

    1997-06-01

    Whereas the Internet has been greatly publicized in the past few years, its effects on education are still largely unexplored. Here, we discuss the future of the Internet itself and the effect on education. Expanding educational and commercial requirements will result in improved bandwidth and connectivity. Larger address spaces will be required, and the next generation of Internet Protocols will provide the addressability required. The real question—how will all of these changes affect education—is explored here. We believe that Internet resources will be a superb supplement to education, but not replace either tutored learning or written texts.

  14. Blister pouches for effective reagent storage and release for low cost point-of-care diagnostic applications

    NASA Astrophysics Data System (ADS)

    Smith, Suzanne; Sewart, Rene; Land, Kevin; Roux, Pieter; Gärtner, Claudia; Becker, Holger

    2016-03-01

    Lab-on-a-chip devices are often applied to point-of-care diagnostic solutions as they are low-cost, compact, disposable, and require only small sample volumes. For such devices, various reagents are required for sample preparation and analysis and, for an integrated solution to be realized, on-chip reagent storage and automated introduction are required. This work describes the implementation and characterization of effective liquid reagent storage and release mechanisms utilizing blister pouches applied to various point-of-care diagnostic device applications. The manufacturing aspects as well as performance parameters are evaluated.

  15. A Conserved GPG-Motif in the HIV-1 Nef Core Is Required for Principal Nef-Activities

    PubMed Central

    Martínez-Bonet, Marta; Palladino, Claudia; Briz, Veronica; Rudolph, Jochen M.; Fackler, Oliver T.; Relloso, Miguel; Muñoz-Fernandez, Maria Angeles; Madrid, Ricardo

    2015-01-01

    To find out new determinants required for Nef activity we performed a functional alanine scanning analysis along a discrete but highly conserved region at the core of HIV-1 Nef. We identified the GPG-motif, located at the 121–137 region of HIV-1 NL4.3 Nef, as a novel protein signature strictly required for the p56Lck dependent Nef-induced CD4-downregulation in T-cells. Since the Nef-GPG motif was dispensable for CD4-downregulation in HeLa-CD4 cells, Nef/AP-1 interaction and Nef-dependent effects on Tf-R trafficking, the observed effects on CD4 downregulation cannot be attributed to structure constraints or to alterations on general protein trafficking. Besides, we found that the GPG-motif was also required for Nef-dependent inhibition of ring actin re-organization upon TCR triggering and MHCI downregulation, suggesting that the GPG-motif could actively cooperate with the Nef PxxP motif for these HIV-1 Nef-related effects. Finally, we observed that the Nef-GPG motif was required for optimal infectivity of those viruses produced in T-cells. According to these findings, we propose the conserved GPG-motif in HIV-1 Nef as functional region required for HIV-1 infectivity and therefore with a potential interest for the interference of Nef activity during HIV-1 infection. PMID:26700863

  16. 40 CFR 721.4469 - Imidazolethione.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... required by this paragraph shall also include the following statements: This substance may cause thyroid cancer. This substance may cause thyroid effects. (b) Specific requirements. The provisions of subpart A...

  17. 40 CFR 721.4469 - Imidazolethione.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... required by this paragraph shall also include the following statements: This substance may cause thyroid cancer. This substance may cause thyroid effects. (b) Specific requirements. The provisions of subpart A...

  18. 40 CFR 721.4469 - Imidazolethione.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... required by this paragraph shall also include the following statements: This substance may cause thyroid cancer. This substance may cause thyroid effects. (b) Specific requirements. The provisions of subpart A...

  19. 40 CFR 721.4469 - Imidazolethione.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... required by this paragraph shall also include the following statements: This substance may cause thyroid cancer. This substance may cause thyroid effects. (b) Specific requirements. The provisions of subpart A...

  20. 40 CFR 721.4469 - Imidazolethione.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... required by this paragraph shall also include the following statements: This substance may cause thyroid cancer. This substance may cause thyroid effects. (b) Specific requirements. The provisions of subpart A...

  1. Trends in measurement of solar vector magnetic fields using the Zeeman effect

    NASA Technical Reports Server (NTRS)

    Harvey, J. W.

    1985-01-01

    Trends in spectropolarimetry as applied to the problem of Zeeman effect measurement are discussed. The use of detector arrays to improve observing efficiency is obtained. Which required new polarization modulation schemes that match the time required to read detector arrays. Another significant trend is narrowband filters, to improve angular and temporal coverage, and to Fourier transform spectrometers, to improve spectral coverage and precision. Low-polarization designs and improved methods for compensating instrumental polarization were developed. A requirement for high angular resolution suggests using adaptive optical devices to subdue the effects of bad seeing. The ultimate strategy to beat the seeing is to loft the telescope above the atmosphere such as is planned with a 30-cm telescope in 1985 and a 1250-cm telescope in 1990.

  2. An Engineering Method of Civil Jet Requirements Validation Based on Requirements Project Principle

    NASA Astrophysics Data System (ADS)

    Wang, Yue; Gao, Dan; Mao, Xuming

    2018-03-01

    A method of requirements validation is developed and defined to meet the needs of civil jet requirements validation in product development. Based on requirements project principle, this method will not affect the conventional design elements, and can effectively connect the requirements with design. It realizes the modern civil jet development concept, which is “requirement is the origin, design is the basis”. So far, the method has been successfully applied in civil jet aircraft development in China. Taking takeoff field length as an example, the validation process and the validation method of the requirements are detailed introduced in the study, with the hope of providing the experiences to other civil jet product design.

  3. Reaching Out.

    ERIC Educational Resources Information Center

    Porter, Randall C.

    1999-01-01

    Discusses technology and equipment requirements for developing an effective distance-learning classroom. Areas covered include cabling, the control booth, microphones, acoustics, lighting, heating and air conditioning, cameras, video monitors, staffing, and power requirements. (GR)

  4. DfM requirements and ROI analysis for system-on-chip

    NASA Astrophysics Data System (ADS)

    Balasinski, Artur

    2005-11-01

    DfM (Design-for-Manufacturability) has become staple requirement beyond 100 nm technology node for efficient generation of mask data, cost reduction, and optimal circuit performance. Layout pattern has to comply to many requirements pertaining to database structure and complexity, suitability for image enhancement by the optical proximity correction, and mask data pattern density and distribution over the image field. These requirements are of particular complexity for Systems-on-Chip (SoC). A number of macro-, meso-, and microscopic effects such as reticle macroloading, planarization dishing, and pattern bridging or breaking would compromise fab yield, device performance, or both. In order to determine the optimal set of DfM rules applicable to the particular designs, Return-on-Investment and Failure Mode and Effect Analysis (FMEA) are proposed.

  5. Why cost-effectiveness should trump (clinical) effectiveness: the ethical economics of the South West quadrant.

    PubMed

    Dowie, Jack

    2004-05-01

    In many health decision making situations there is a requirement that the effectiveness of interventions, usually their 'clinical' effectiveness, be established, as well as their cost-effectiveness. Often indeed this is effectively a prior requirement for their cost-effectiveness being investigated. If, however, one accepts the ethical argument for using a threshold incremental cost-effectiveness ratio (ICER) for interventions that are more effective but more costly (i.e. fall in the NE quadrant of the cost-effectiveness plane), one should apply the same decision rule in the SW quadrant, where the intervention is less effective but less costly. This implication is present in most standard treatments of cost-effectiveness analysis, including recent stochastic versions, and had gone relatively unquestioned within the discipline until the recent suggestion that the ICER threshold might be 'kinked'. A kinked threshold would, O'Brien et al. argue, better reflect the asymmetrical individual preferences found in empirical studies of consumer's willingness to pay and willingness to accept and justify different decision rules in the NE and SW quadrants. We reject the validity of such asymmetric preferences in the context of public health care decisions and consider and counter the two main 'ethical' objections that probably underlie the asymmetry in this case--the objection to 'taking away' and the objection to being required to undergo treatment that is less effective than no treatment at all. Copyright 2004 John Wiley & Sons, Ltd.

  6. Environmental Effects of Agricultural Practices - Summary of Workshop Held on June 14-16, 2005

    USGS Publications Warehouse

    ,

    2006-01-01

    A meeting between the U.S. Geological Survey (USGS) and its partners was held June 14-16, 2005, in Denver, CO, to discuss science issues and needs related to agricultural practices. The goals of the meeting were to learn about the (1) effects of agricultural practices on the environment and (2) tools for identifying and quantifying those effects. Achieving these goals required defining the environmental concerns, developing scientific actions to address assessment of environmental effects, and creating collaborations to identify future research requirements and technical gaps. Five areas of concern were discussed-emerging compounds; water availability; genetically modified organisms; effects of conservation practices on ecosystems; and data, methods, and tools for assessing effects of agricultural practices.

  7. Effectiveness of Rapid Cooling as a Method of Euthanasia for Young Zebrafish (Danio rerio).

    PubMed

    Wallace, Chelsea K; Bright, Lauren A; Marx, James O; Andersen, Robert P; Mullins, Mary C; Carty, Anthony J

    2018-01-01

    Despite increased use of zebrafish (Danio rerio) in biomedical research, consistent information regarding appropriate euthanasia methods, particularly for embryos, is sparse. Current literature indicates that rapid cooling is an effective method of euthanasia for adult zebrafish, yet consistent guidelines regarding zebrafish younger than 6 mo are unavailable. This study was performed to distinguish the age at which rapid cooling is an effective method of euthanasia for zebrafish and the exposure times necessary to reliably euthanize zebrafish using this method. Zebrafish at 3, 4, 7, 14, 16, 19, 21, 28, 60, and 90 d postfertilization (dpf) were placed into an ice water bath for 5, 10, 30, 45, or 60 min (n = 12 to 40 per group). In addition, zebrafish were placed in ice water for 12 h (age ≤14 dpf) or 30 s (age ≥14 dpf). After rapid cooling, fish were transferred to a recovery tank and the number of fish alive at 1, 4, and 12-24 h after removal from ice water was documented. Euthanasia was defined as a failure when evidence of recovery was observed at any point after removal from ice water. Results showed that younger fish required prolonged exposure to rapid cooling for effective euthanasia, with the required exposure time decreasing as fish age. Although younger fish required long exposure times, animals became immobilized immediately upon exposure to the cold water, and behavioral indicators of pain or distress rarely occurred. We conclude that zebrafish 14 dpf and younger require as long as 12 h, those 16 to 28 dpf of age require 5 min, and those older than 28 dpf require 30 s minimal exposure to rapid cooling for reliable euthanasia.

  8. Inhibition by Agrobacterium tumefaciens and Pseudomonas savastanoi of development of the hypersensitive response elicited by Pseudomonas syringae pv. phaseolicola.

    PubMed Central

    Robinette, D; Matthysse, A G

    1990-01-01

    Injection into tobacco leaves of biotype 1 Agrobacterium tumefaciens or of Pseudomonas savastanoi inhibited the development of a visible hypersensitive response to the subsequent injection at the same site of Pseudomonas syringae pv. phaseolicola. This interference with the hypersensitive response was not seen with injection of bacterial growth medium or Escherichia coli cells. Live A. tumefaciens cells were required for the inhibitory effect. Various mutants and strains of A. tumefaciens were examined to determine the genes involved. Known chromosomal mutations generally had no effect on the ability of A. tumefaciens to inhibit the hypersensitive response, except for chvB mutants which showed a reduced (but still significant) inhibition of the hypersensitive response. Ti plasmid genes appeared to be required for the inhibition of the hypersensitive response. The bacteria did not need to be virulent in order to inhibit the hypersensitive response. Deletion of the vir region from pTi had no effect on the inhibition. However, the T region of the Ti plasmid was required for inhibition. Studies of transposon mutants suggested that the tms but not tmr or ocs genes were required. These genes were not acting after transfer to plant cells since they were effective in strains lacking vir genes and thus unable to transfer DNA to plant cells. The results suggest that the expression of the tms genes in the bacteria may inhibit the development of the hypersensitive response by the plant. An examination of the genes required in P. savastanoi for the inhibition of the hypersensitive response suggested that bacterial production of auxin was also required for the inhibition of the hypersensitive response by these bacteria. Images PMID:2211508

  9. Consideration of Fuel Requirements for Supersonic Transport Operation

    NASA Technical Reports Server (NTRS)

    Stickle, Joseph W.

    1965-01-01

    An analysis of the interaction of operational environment and aircraft characteristics of the supersonic transport (SST) in the areas of design-range and reserve-fuel requirements has been made. Design-range requirements are considered in relation to the effects of wind, temperature, flight-level assignment, and payload variation. An approach toward combining en route and holding reserve requirements while maintaining protection equivalent to that provided subsonic jet transport operations by the present civil air regulation en route plus holding reserves is given. This approach results in a savings in reserve fuel over that required by separate requirements.

  10. A randomised control study comparing the Infant Flow Driver with nasal continuous positive airway pressure in preterm infants.

    PubMed

    Mazzella, M; Bellini, C; Calevo, M G; Campone, F; Massocco, D; Mezzano, P; Zullino, E; Scopesi, F; Arioni, C; Bonacci, W; Serra, G

    2001-09-01

    To compare the effectiveness of the Infant Flow Driver (IFD) with single prong nasal continuous positive airway pressure (nCPAP) in preterm neonates affected by respiratory distress syndrome. Randomised controlled study. Between September 1997 and March 1999, 36 preterm infants who were eligible for CPAP treatment were randomly selected for either nCPAP or IFD and studied prospectively for changes in oxygen requirement and/or respiratory rate. The requirement for mechanical ventilation, complications of treatment, and effects on mid-term outcome were also evaluated. Use of the IFD had a significantly beneficial effect on both oxygen requirement and respiratory rate (p < 0.0001) when compared with nCPAP. Moreover, O(2) requirement and respiratory rate were significantly decreased by four hours (p < 0.001 and p < 0.03 respectively). The probability of remaining supplementary oxygen free over the first 48 hours of treatment was significantly higher in patients treated with the IFD than with nCPAP (p < 0.02). IFD treated patients had a higher success (weaning) rate (94% v 72 %) and shorter duration of treatment (49.3 (31) v 56 (29.7) hours respectively; mean (SD)), although the difference was not significant. IFD appears to be a feasible device for managing respiratory distress syndrome in preterm infants, and benefits may be had with regard to oxygen requirement and respiratory rate when compared with nCPAP. The trend towards reduced requirement for mechanical ventilation, shorter clinical recovery time, and shorter duration of treatment requires further evaluation in a multicentre randomised clinical trial.

  11. 40 CFR 52.1224 - General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1224 General requirements. (a... information and data was delegated to the Minnesota Pollution Control Agency effective October 6, 1977. [37 FR...

  12. 40 CFR 52.1224 - General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1224 General requirements. (a... information and data was delegated to the Minnesota Pollution Control Agency effective October 6, 1977. [37 FR...

  13. 40 CFR 52.1224 - General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1224 General requirements. (a... information and data was delegated to the Minnesota Pollution Control Agency effective October 6, 1977. [37 FR...

  14. 40 CFR 52.1224 - General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1224 General requirements. (a... information and data was delegated to the Minnesota Pollution Control Agency effective October 6, 1977. [37 FR...

  15. 40 CFR 52.1224 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1224 General requirements. (a... information and data was delegated to the Minnesota Pollution Control Agency effective October 6, 1977. [37 FR...

  16. Planning an Effective Child Care Center.

    ERIC Educational Resources Information Center

    Wright, Rodney; Wright, Sydney

    This conference presentation offers general guidelines for planning a new child care facility. Particular attention is given to site selection, space requirements, functional requirements, materials, climate, and choosing an architect. (RH)

  17. 40 CFR 280.42 - Requirements for hazardous substance UST systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) SOLID WASTES (CONTINUED) TECHNICAL STANDARDS AND CORRECTIVE ACTION REQUIREMENTS FOR OWNERS AND... effective corrective action technologies, health risks, and chemical and physical properties of the stored...

  18. Environmental Requirements Management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cusack, Laura J.; Bramson, Jeffrey E.; Archuleta, Jose A.

    2015-01-08

    CH2M HILL Plateau Remediation Company (CH2M HILL) is the U.S. Department of Energy (DOE) prime contractor responsible for the environmental cleanup of the Hanford Site Central Plateau. As part of this responsibility, the CH2M HILL is faced with the task of complying with thousands of environmental requirements which originate from over 200 federal, state, and local laws and regulations, DOE Orders, waste management and effluent discharge permits, Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) response and Resource Conservation and Recovery Act (RCRA) corrective action documents, and official regulatory agency correspondence. The challenge is to manage this vast number ofmore » requirements to ensure they are appropriately and effectively integrated into CH2M HILL operations. Ensuring compliance with a large number of environmental requirements relies on an organization’s ability to identify, evaluate, communicate, and verify those requirements. To ensure that compliance is maintained, all changes need to be tracked. The CH2M HILL identified that the existing system used to manage environmental requirements was difficult to maintain and that improvements should be made to increase functionality. CH2M HILL established an environmental requirements management procedure and tools to assure that all environmental requirements are effectively and efficiently managed. Having a complete and accurate set of environmental requirements applicable to CH2M HILL operations will promote a more efficient approach to: • Communicating requirements • Planning work • Maintaining work controls • Maintaining compliance« less

  19. 40 CFR 1700.12 - Petition requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Petition requirements. 1700.12 Section... VESSELS OF THE ARMED FORCES Effect on States State Petition for Review § 1700.12 Petition requirements. A petition for review of a determination or standard must include: (a) The discharge from § 1700.4 or § 1700...

  20. How Social Contexts Support and Shape Language Development

    ERIC Educational Resources Information Center

    Hoff, Erika

    2006-01-01

    The human potential for language is based in human biology but makes requirements of the social environment to be realized. This paper reports evidence regarding (1) the nature of those environmental requirements, (2) the ways in which the varied social contexts in which children live meet those requirements, and (3) the effects of environmental…

  1. 2 CFR 170.200 - Requirements for program announcements, regulations, and application instructions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Requirements for program announcements, regulations, and application instructions. 170.200 Section 170.200 Grants and Agreements Office of Management... Transparency Act reporting requirements; and (2) That either: (i) Is issued on or after the effective date of...

  2. 2 CFR 170.200 - Requirements for program announcements, regulations, and application instructions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Requirements for program announcements, regulations, and application instructions. 170.200 Section 170.200 Grants and Agreements Office of Management... Transparency Act reporting requirements; and (2) That either: (i) Is issued on or after the effective date of...

  3. 78 FR 24684 - Self Reporting of Out-of-State Convictions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-26

    ... notification by way of the FMCSA Web site and other social media. The Agency however, believes the requirement...-reporting requirements under 49 CFR 383.31 using a Federal Register notice, its Web site and social media... seq.) requires Federal agencies to consider the effects of the regulatory action on small business and...

  4. Estimating the energetic cost of feeding excess dietary nitrogen to dairy cows

    USDA-ARS?s Scientific Manuscript database

    Feeding N in excess of requirements could require the use of additional energy to synthesize and excrete urea, however, the amount energy required is unclear. Little progress has been made on this topic in recent decades so an extension of work published in 1970 was conducted to quantify the effect ...

  5. 78 FR 39036 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ... applicable non-financial listing standard requirements, including, without limitation, the requirements of... financial statements for a full fiscal year commencing on a date after the date of filing with the...-K, including all required audited financial statements (the ``Reverse Merger Form 8-K'').\\5\\ In...

  6. An Analysis of Skill Requirements for Operators of Amphibious Air Cushion Vehicles (ACVs).

    ERIC Educational Resources Information Center

    McKnight, A. James; And Others

    This report describes the skills required in the operation of an amphibious air cushion vehicle (ACV) in Army tactical and logistic missions. The research involved analyzing ACV characteristics, operating requirements, environmental effects, and results of a simulation experiment. The analysis indicates that ACV operation is complicated by an…

  7. 78 FR 2475 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ...'') as approved by the Commission \\9\\ and proposed changes to market making quoting requirements through... of the Plan and proposed changes to market making quoting requirements. Thus, the Exchange believes... control, in turn, enables Market Makers to comply independently with the requirements of Regulation SHO \\5...

  8. 78 FR 2477 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ...'') as approved by the Commission \\9\\ and proposed changes to market making quoting requirements through... date in light of the Plan and proposed changes to market making quoting requirements. Thus, the... control, in turn, enables Market Makers to comply independently with the requirements of Regulation SHO \\5...

  9. 40 CFR 87.3 - General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Definitions. § 87.3 General requirements. Link to an amendment published at 77 FR 36381, June 18, 2012. (a... Date Note: At 77 FR 36381, June 18, 2012, § 87.3 was revised, effective July 18, 2012. For the... 40 Protection of Environment 21 2012-07-01 2012-07-01 false General requirements. 87.3 Section 87...

  10. 46 CFR 71.50-17 - Eligibility requirements for the Alternative Hull Examination (AHE) Program for certain passenger...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Eligibility requirements for the Alternative Hull...-17 Eligibility requirements for the Alternative Hull Examination (AHE) Program for certain passenger... aluminum; (2) It has an effective hull protection system; (3) It has operated exclusively in fresh water...

  11. 77 FR 12347 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    ...-2011-36). \\12\\ Web CRD is the central licensing and registration system for the U.S. securities... Clerks are not subject to continuing education requirements; the Exchange is not proposing any... education requirements. The Exchange intends to add continuing education requirements for Market Makers...

  12. Mass production of silicon pore optics for ATHENA

    NASA Astrophysics Data System (ADS)

    Wille, Eric; Bavdaz, Marcos; Collon, Maximilien

    2016-07-01

    Silicon Pore Optics (SPO) provide high angular resolution with low effective area density as required for the Advanced Telescope for High Energy Astrophysics (Athena). The x-ray telescope consists of several hundreds of SPO mirror modules. During the development of the process steps of the SPO technology, specific requirements of a future mass production have been considered right from the beginning. The manufacturing methods heavily utilise off-the-shelf equipment from the semiconductor industry, robotic automation and parallel processing. This allows to upscale the present production flow in a cost effective way, to produce hundreds of mirror modules per year. Considering manufacturing predictions based on the current technology status, we present an analysis of the time and resources required for the Athena flight programme. This includes the full production process starting with Si wafers up to the integration of the mirror modules. We present the times required for the individual process steps and identify the equipment required to produce two mirror modules per day. A preliminary timeline for building and commissioning the required infrastructure, and for flight model production of about 1000 mirror modules, is presented.

  13. Pressurant requirements for discharge of liquid methane from a 1.52-meter-(5-ft-) diameter spherical tank under both static and slosh conditions

    NASA Technical Reports Server (NTRS)

    Dewitt, R. L.; Mcintire, T. O.

    1974-01-01

    Pressurized expulsion tests were conducted to determine the effect of various physical parameters on the pressurant gas (methane, helium, hydrogen, and nitrogen) requirements during the expulsion of liquid methane from a 1.52-meter-(5-ft-) diameter spherical tank and to compare results with those predicted by an analytical program. Also studied were the effects on methane, helium, and hydrogen pressurant requirements of various slosh excitation frequencies and amplitudes, both with and without slosh suppressing baffles in the tank. The experimental results when using gaseous methane, helium, and hydrogen show that the predictions of the analytical program agreed well with the actual pressurant requirements for static tank expulsions. The analytical program could not be used for gaseous nitrogen expulsions because of the large quantities of nitrogen which can dissolve in liquid methane. Under slosh conditions, a pronounced increase in gaseous methane requirements was observed relative to results obtained for the static tank expulsions. Slight decreases in the helium and hydrogen requirements were noted under similar test conditions.

  14. Data governance requirements for distributed clinical research networks: triangulating perspectives of diverse stakeholders.

    PubMed

    Kim, Katherine K; Browe, Dennis K; Logan, Holly C; Holm, Roberta; Hack, Lori; Ohno-Machado, Lucila

    2014-01-01

    There is currently limited information on best practices for the development of governance requirements for distributed research networks (DRNs), an emerging model that promotes clinical data reuse and improves timeliness of comparative effectiveness research. Much of the existing information is based on a single type of stakeholder such as researchers or administrators. This paper reports on a triangulated approach to developing DRN data governance requirements based on a combination of policy analysis with experts, interviews with institutional leaders, and patient focus groups. This approach is illustrated with an example from the Scalable National Network for Effectiveness Research, which resulted in 91 requirements. These requirements were analyzed against the Fair Information Practice Principles (FIPPs) and Health Insurance Portability and Accountability Act (HIPAA) protected versus non-protected health information. The requirements addressed all FIPPs, showing how a DRN's technical infrastructure is able to fulfill HIPAA regulations, protect privacy, and provide a trustworthy platform for research. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  15. Review of: Methods to complete watershed analysis on Pacific Lumber lands in Northern California

    Treesearch

    L. M. Reid

    1999-01-01

    The three questions of primary concern for this review are: 1) are the WDNR modules adequately and validly modified to suit local conditions, as required by the HCP/SYP? 2) is there an adequate "distinct cumulative effects assessment" method, as required by the HCP/SYP? 3) will the cumulative effects assessment method and the modified WDNR modules be...

  16. 40 CFR 132.6 - Application of part 132 requirements in Great Lakes States and Tribes.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the State of Indiana. (b) Effective September 5, 2000, the requirements of Procedure 3 in Appendix F... in the States of Indiana, Michigan and Ohio. (d) Effective November 6, 2000, § 132.4(d)(2) shall... a total concentration. (b) Chemical mA bA Conversion factor (CF) Cadmium a,b 1.128 −3.6867 0.85...

  17. 40 CFR 132.6 - Application of part 132 requirements in Great Lakes States and Tribes.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the State of Indiana. (b) Effective September 5, 2000, the requirements of Procedure 3 in Appendix F... in the States of Indiana, Michigan and Ohio. (d) Effective November 6, 2000, § 132.4(d)(2) shall... a total concentration. (b) Chemical mA bA Conversion factor (CF) Cadmium a,b 1.128 −3.6867 0.85...

  18. 2 CFR 25.205 - Effect of noncompliance with a requirement to obtain a DUNS number or register in the CCR.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Effect of noncompliance with a requirement to obtain a DUNS number or register in the CCR. 25.205 Section 25.205 Grants and Agreements Office of...; and (2) May use that determination as a basis for making an award to another applicant. ...

  19. Effects of Requiring Students to Meet High Expectation Levels within an On-Line Homework Environment

    ERIC Educational Resources Information Center

    Weber, William J., Jr.

    2010-01-01

    On-line homework is becoming a larger part of mathematics classrooms each year. Thus, ways to maximize the effectiveness of on-line homework for both students and teachers must be investigated. This study sought to provide one possible answer to this aim, by requiring students to achieve at least 50% for any on-line homework assignment in order to…

  20. Connecting Marketing and Implementation Research and Library Program Development: A Case Study of the Implementation of [U.S.] National Guidelines and Standards.

    ERIC Educational Resources Information Center

    Haycock, Ken; Cavill, Pat

    This case study examined: (1) what market research is required for planning for the implementation of "Information Power: Building Partnerships for Learning," the 1998 national guidelines for effective school library media programs; (2) what issues need to be addressed and what target audiences are required to effect change, as well as…

  1. 31 CFR 30.17 - Q-17: How do the effective date provisions apply with respect to the requirements under section...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Q-17: How do the effective date provisions apply with respect to the requirements under section 111 of EESA? 30.17 Section 30.17 Money and Finance: Treasury Office of the Secretary of the Treasury TARP STANDARDS FOR COMPENSATION AND CORPORATE...

  2. 10 CFR 1042.125 - Effect of other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...; sections 704 and 855 of the Public Health Service Act (42 U.S.C. 295m, 298b-2); Title VII of the Civil Rights Act of 1964 (42 U.S.C. 2000e et seq.); the Equal Pay Act of 1963 (29 U.S.C. 206); and any other Act of Congress or Federal regulation. (b) Effect of State or local law or other requirements. The...

  3. 29 CFR 36.125 - Effect of other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; sections 704 and 855 of the Public Health Service Act (42 U.S.C. 295m, 298b-2); Title VII of the Civil Rights Act of 1964 (42 U.S.C. 2000e et seq.); the Equal Pay Act of 1963 (29 U.S.C. 206); and any other Act of Congress or Federal regulation. (b) Effect of State or local law or other requirements. The...

  4. Health human resource planning requires an effective staff retention policy.

    PubMed

    Rondeau, Kent V

    2002-01-01

    Planning for health human resources requires us to think about the forces and factors that attract healthcare professionals to their jobs and keep them there. However, the forces for attracting healthcare employees to a job are not the same as those factors that keep them there. Without effective recruitment and retention policies for healthcare professionals, planning initiatives will continue to be ineffective.

  5. Requirements for Weatherproofing Thin Shell Concrete Roofs. Proceedings of the Conference of Building Research Institute, Division of Engineering and Industrial Research (Spring 1961).

    ERIC Educational Resources Information Center

    National Academy of Sciences - National Research Council, Washington, DC.

    Topics discussed include--(1) requirements for weatherproofing and sealant materials for thin shell concrete roof, (2) effect of physical factors on weatherproofing of thin shell concrete roofs, (3) problems and limitations imposed by thin shell concrete roofs and their effect on weatherproofing and sealant materials, and (4) properties and uses…

  6. Considerations in the use of models available for fuel treatment analysis

    Treesearch

    Charles W. McHugh

    2006-01-01

    Fire managers are required to evaluate and justify the effectiveness of planned fuel treatments in modifying fire growth, behavior and effects on resources and assets. With the number of models currently available, today’s fire manager can become overwhelmed when deciding which model to use. Each model has a required level of expertise in order to develop the necessary...

  7. Failure Modes Effects and Criticality Analysis, an Underutilized Safety, Reliability, Project Management and Systems Engineering Tool

    NASA Astrophysics Data System (ADS)

    Mullin, Daniel Richard

    2013-09-01

    The majority of space programs whether manned or unmanned for science or exploration require that a Failure Modes Effects and Criticality Analysis (FMECA) be performed as part of their safety and reliability activities. This comes as no surprise given that FMECAs have been an integral part of the reliability engineer's toolkit since the 1950s. The reasons for performing a FMECA are well known including fleshing out system single point failures, system hazards and critical components and functions. However, in the author's ten years' experience as a space systems safety and reliability engineer, findings demonstrate that the FMECA is often performed as an afterthought, simply to meet contract deliverable requirements and is often started long after the system requirements allocation and preliminary design have been completed. There are also important qualitative and quantitative components often missing which can provide useful data to all of project stakeholders. These include; probability of occurrence, probability of detection, time to effect and time to detect and, finally, the Risk Priority Number. This is unfortunate as the FMECA is a powerful system design tool that when used effectively, can help optimize system function while minimizing the risk of failure. When performed as early as possible in conjunction with writing the top level system requirements, the FMECA can provide instant feedback on the viability of the requirements while providing a valuable sanity check early in the design process. It can indicate which areas of the system will require redundancy and which areas are inherently the most risky from the onset. Based on historical and practical examples, it is this author's contention that FMECAs are an immense source of important information for all involved stakeholders in a given project and can provide several benefits including, efficient project management with respect to cost and schedule, system engineering and requirements management, assembly integration and test (AI&T) and operations if applied early, performed to completion and updated along with system design.

  8. A Mass Computation Model for Lightweight Brayton Cycle Regenerator Heat Exchangers

    NASA Technical Reports Server (NTRS)

    Juhasz, Albert J.

    2010-01-01

    Based on a theoretical analysis of convective heat transfer across large internal surface areas, this paper discusses the design implications for generating lightweight gas-gas heat exchanger designs by packaging such areas into compact three-dimensional shapes. Allowances are made for hot and cold inlet and outlet headers for assembly of completed regenerator (or recuperator) heat exchanger units into closed cycle gas turbine flow ducting. Surface area and resulting volume and mass requirements are computed for a range of heat exchanger effectiveness values and internal heat transfer coefficients. Benefit cost curves show the effect of increasing heat exchanger effectiveness on Brayton cycle thermodynamic efficiency on the plus side, while also illustrating the cost in heat exchanger required surface area, volume, and mass requirements as effectiveness is increased. The equations derived for counterflow and crossflow configurations show that as effectiveness values approach unity, or 100 percent, the required surface area, and hence heat exchanger volume and mass tend toward infinity, since the implication is that heat is transferred at a zero temperature difference. To verify the dimensional accuracy of the regenerator mass computational procedure, calculation of a regenerator specific mass, that is, heat exchanger weight per unit working fluid mass flow, is performed in both English and SI units. Identical numerical values for the specific mass parameter, whether expressed in lb/(lb/sec) or kg/(kg/sec), show the dimensional consistency of overall results.

  9. A Mass Computation Model for Lightweight Brayton Cycle Regenerator Heat Exchangers

    NASA Technical Reports Server (NTRS)

    Juhasz, Albert J.

    2010-01-01

    Based on a theoretical analysis of convective heat transfer across large internal surface areas, this paper discusses the design implications for generating lightweight gas-gas heat exchanger designs by packaging such areas into compact three-dimensional shapes. Allowances are made for hot and cold inlet and outlet headers for assembly of completed regenerator (or recuperator) heat exchanger units into closed cycle gas turbine flow ducting. Surface area and resulting volume and mass requirements are computed for a range of heat exchanger effectiveness values and internal heat transfer coefficients. Benefit cost curves show the effect of increasing heat exchanger effectiveness on Brayton cycle thermodynamic efficiency on the plus side, while also illustrating the cost in heat exchanger required surface area, volume, and mass requirements as effectiveness is increased. The equations derived for counterflow and crossflow configurations show that as effectiveness values approach unity, or 100 percent, the required surface area, and hence heat exchanger volume and mass tend toward infinity, since the implication is that heat is transferred at a zero temperature difference. To verify the dimensional accuracy of the regenerator mass computational procedure, calculation of a regenerator specific mass, that is, heat exchanger weight per unit working fluid mass flow, is performed in both English and SI units. Identical numerical values for the specific mass parameter, whether expressed in lb/(lb/sec) or kg/ (kg/sec), show the dimensional consistency of overall results.

  10. Study design options in evaluating gene-environment interactions: practical considerations for a planned case-control study of pediatric leukemia.

    PubMed

    Goodman, Michael; Dana Flanders, W

    2007-04-01

    We compare methodological approaches for evaluating gene-environment interaction using a planned study of pediatric leukemia as a practical example. We considered three design options: a full case-control study (Option I), a case-only study (Option II), and a partial case-control study (Option III), in which information on controls is limited to environmental exposure only. For each design option we determined its ability to measure the main effects of environmental factor E and genetic factor G, and the interaction between E and G. Using the leukemia study example, we calculated sample sizes required to detect and odds ratio (OR) of 2.0 for E alone, an OR of 10 for G alone and an interaction G x E of 3. Option I allows measuring both main effects and interaction, but requires a total sample size of 1,500 cases and 1,500 controls. Option II allows measuring only interaction, but requires just 121 cases. Option III allows calculating the main effect of E, and interaction, but not the main effect of G, and requires a total of 156 cases and 133 controls. In this case, the partial case-control study (Option III) appears to be more efficient with respect to its ability to answer the research questions for the amount of resources required. The design options considered in this example are not limited to observational epidemiology and may be applicable in studies of pharmacogenomics, survivorship, and other areas of pediatric ALL research.

  11. Characterization of Electrochemically Generated Silver

    NASA Technical Reports Server (NTRS)

    Adam, Niklas; Martinez, James; Carrier, Chris

    2014-01-01

    Silver biocide offers a potential advantage over iodine, the current state of the art in US spacecraft disinfection technology, in that silver can be safely consumed by the crew. Low concentrations of silver (<500 ppb) have been shown to kill bacteria in water systems and keep it safe for potability. Silver does not require hardware to remove it from a water system, and therefore can provide a simpler means for disinfecting water. The Russian segment of the International Space Station has utilized an electrochemically generated silver solution, which is colloidal in nature. To be able to reliably provide a silver biocide to drinking water by electrochemical means would reduce mass required for removing another biocide such as iodine from the water. This would also aid in crew time required to replace iodine removal cartridges. Future long term missions would benefit from electrochemically produced silver as the biocide could be produced on demand and requires only a small concentration to be effective. Since it can also be consumed safely, there is less mass in removal hardware and little consumables required for production. The goal of this project initially is to understand the nature of the electrochemically produced silver, the particle sizes produced by the electrochemical cell and the effect that voltage adjustment has on the particle size. In literature, it has been documented that dissolved oxygen and pH have an effect on the ionization of the electrochemical silver so those parameters would be measured and possibly adjusted to understand their effect on the silver.

  12. 40 CFR 725.67 - Applications to exempt new microorganisms from this part.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., small business, and technological innovation. (3) Specific requirements. In addition to the requirements... effect on the national economy, small business, technological innovation, the environment, and public...

  13. 40 CFR 725.67 - Applications to exempt new microorganisms from this part.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., small business, and technological innovation. (3) Specific requirements. In addition to the requirements... effect on the national economy, small business, technological innovation, the environment, and public...

  14. 40 CFR 92.1006 - Refueling requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Requirements Applicable to... designed in such a manner so as not to render inoperative or reduce the effectiveness of the controls on...

  15. Neutron, gamma ray and post-irradiation thermal annealing effects on power semiconductor switches

    NASA Technical Reports Server (NTRS)

    Schwarze, G. E.; Frasca, A. J.

    1991-01-01

    The effects of neutron and gamma rays on the electrical and switching characteristics of power semiconductor switches must be known and understood by the designer of the power conditioning, control, and transmission subsystem of space nuclear power systems. The SP-100 radiation requirements at 25 m from the nuclear source are a neutron fluence of 10(exp 13) n/sq cm and a gamma dose of 0.5 Mrads. Experimental data showing the effects of neutrons and gamma rays on the performance characteristics of power-type NPN Bipolar Junction Transistors (BJTs), Metal-Oxide-Semiconductor Field Effect Transistors (MOSFETs), and Static Induction Transistors (SITs) are presented. These three types of devices were tested at radiation levels which met or exceeded the SP-100 requirements. For the SP-100 radiation requirements, the BJTs were found to be most sensitive to neutrons, the MOSFETs were most sensitive to gamma rays, and the SITs were only slightly sensitive to neutrons. Post-irradiation thermal anneals at 300 K and up to 425 K were done on these devices and the effectiveness of these anneals are also discussed.

  16. Ecological issues related to ozone: agricultural issues.

    PubMed

    Fuhrer, Jürg; Booker, Fitzgerald

    2003-06-01

    Research on the effects of ozone on agricultural crops and agro-ecosystems is needed for the development of regional emission reduction strategies, to underpin practical recommendations aiming to increase the sustainability of agricultural land management in a changing environment, and to secure food supply in regions with rapidly growing populations. Major limitations in current knowledge exist in several areas: (1) Modelling of ozone transfer and specifically stomatal ozone uptake under variable environmental conditions, using robust and well-validated dynamic models that can be linked to large-scale photochemical models lack coverage. (2) Processes involved in the initial reactions of ozone with extracellular and cellular components after entry through the stomata, and identification of key chemical species and their role in detoxification require additional study. (3) Scaling the effects from the level of individual cells to the whole-plant requires, for instance, a better understanding of the effects of ozone on carbon transport within the plant. (4) Implications of long-term ozone effects on community and whole-ecosystem level processes, with an emphasis on crop quality, element cycling and carbon sequestration, and biodiversity of pastures and rangelands require renewed efforts. The UNECE Convention on Long Range Trans-boundary Air Pollution shows, for example, that policy decisions may require the use of integrated assessment models. These models depend on quantitative exposure-response information to link quantitative effects at each level of organization to an effective ozone dose (i.e., the balance between the rate of ozone uptake by the foliage and the rate of ozone detoxification). In order to be effective in a policy, or technological context, results from future research must be funnelled into an appropriate knowledge transfer scheme. This requires data synthesis, up-scaling, and spatial aggregation. At the research level, interactions must be considered between the effects of ozone and factors that are either directly manipulated by man through crop management, or indirectly changed. The latter include elevated atmospheric CO(2), particulate matter, other pollutants such as nitrogen oxides, UV-B radiation, climate and associated soil moisture conditions.

  17. Comparison between videotape and personalized patient education for anticoagulant therapy.

    PubMed

    Stone, S; Holden, A; Knapic, N; Ansell, J

    1989-07-01

    To assess the effectiveness of videotape patient education, 22 patients were randomized to receive either videotape or personalized teaching for oral anticoagulant (warfarin) therapy. Both groups scored significantly higher on a questionnaire designed to assess knowledge gained after instruction, with no significant difference between the two groups. Videotape instruction required substantially less nursing time. A second questionnaire assessed patient satisfaction with respect to both methods, which were rated equally effective and worthwhile. Videotape teaching is an effective and well-accepted alternative form of patient education requiring significantly less personnel time.

  18. Flight Tests of the Sikorsky HNS-1 (Army YR-4B) Helicopter. 2 - Hovering and Vertical-Flight Performance with the Original and an Alternative Set of Main-Rotor Blades, Including a Comparison with Hovering Performance Theory

    DTIC Science & Technology

    1945-04-01

    sustentation at various altitudes in the ground-effect region is shown in figure 2. A hovering point obtained at approximately 400 feet altitude and a...power required. DISCUSSION Ground-effect data.- The effect of rpm on the power— .— required for sustentation is clearly indicated by figure 2. A ret...Alfred ORIG. AGENCY : Langley Memorial Aeronautical Lab., Langley Field, Va. PUBLISHED BY : National Advisory Committee for Aeronautics

  19. 78 FR 63180 - Agency Information Collection Activities OMB Responses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ... 1696.08; Fuels and Fuel Additives: Health-Effects Research Requirements for Manufacturers; 40 CFR part...; Recordkeeping and Reporting Requirements for Allegations of Significant Adverse Reactions to Human Health or the...

  20. Greater Buyer Effectiveness through Automation

    DTIC Science & Technology

    1989-01-01

    assignment to the buyer Coordination - automated routing of requirement package to technical, finance, transportation, packaging, small business ... security , data, safety, etc. Consolidation - automated identification of requirements for identical or similar items for potential consolidation

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