Sample records for ans topical meeting

  1. SETAC Focused Topic Meeting on endocrine-disrupting chemicals: Overview and outcomes

    EPA Science Inventory

    A SETAC North America Focused Topic Meeting (FTM), “Endocrine Disruption: Chemical testing, Risk Assessment Approaches and Implications”, was held 4-6 February, 2014 at the US Environmental Protection Agency (USEPA) conference facility in Research Triangle Park, NC. The meeting,...

  2. PREFACE: The first meeting of the APS Topical Group on Hadronic Physics

    NASA Astrophysics Data System (ADS)

    Barnes, Ted; Godfrey, Steve; Petrov, Alexey A.; Swanson, Eric

    2005-01-01

    The first meeting of the APS Topical Group on Hadronic Physics (`GHP') took place on 24-26 October 2004, at Fermilab. Two factors contributed to the decision to hold this meeting. First, the Topical Group on Hadronic Physics had recently been established, and there was general agreement that a conference devoted to the physics of hadrons was an important group activity. Second, many exciting new experimental results on hadron spectroscopy had been announced recently, and there was intense interest in these new developments. The meeting was very well attended, with over 120 scientists participating; this was triple our original estimate of the likely audience for this meeting. The plenary sessions covered a broad range of topics, as we considered it important to promote communication between the communities pursuing research in different areas of hadron physics. The topics discussed included new results from RHIC on the QGP, the status of experiments on the flavour-exotic pentaquark and other new baryons, the new open-charm Ds and hidden-charm X states, conventional light quark resonances, glueballs and hybrids, and new facilities. Finally, a `town meeting' was held to discuss funding prospects for hadronic physics and related issues, which included a panel discussion with representatives from DOE, NSF and JLab. These plenary sessions were supplemented by 14 parallel sessions, giving a total of approximately 80 presentations. To make the conference more accessible to younger researchers, as well as to simiplify administration, there was no conference fee for this meeting. This was possible as a result of the generous financial support of our hosts at Fermilab, for which we are very appreciative. We are also grateful to Larry Cardman for arranging Jlab assistance in producing and distributing the conference poster, to Gerald Ragghianti for designing the poster and proceedings cover, and to Lali Chatterjee and the Institute of Physics for arranging publication of the

  3. The Optical Society's 2016 topical meeting on optical interference coatings: introduction.

    PubMed

    Ristau, Detlev; Li, Li; Sargent, Robert; Sytchkova, Anna

    2017-02-01

    This feature issue of Applied Optics is dedicated to the 13th Topical Meeting on Optical Interference Coatings, which was held June 19-24, 2016, in Tucson, Arizona, USA. The conference, taking place every three years, is a focal point for global technical interchange in the field of optical interference coatings and provides premier opportunities for people working in the field to present their new advances in research and development. Papers presented at the meeting covered a broad range of topics, including fundamental research on coating design theory, new materials, and deposition and characterization technologies, as well as the vast and growing number of applications in electronic displays, communication, optical instruments, high power and ultra-fast lasers, solar cells, space missions, gravitational wave detection, and many others.

  4. PREFACE: Second Meeting of the APS Topical Group on Hadronic Physics

    NASA Astrophysics Data System (ADS)

    Ernst, David; de Jager, Kees; Roberts, Craig; Sheldon, Paul; Swanson, Eric

    2007-06-01

    The Second Meeting of the APS Topical Group on Hadronic Physics was held on 22-24 October 2006 at the Opryland Resort in Nashville, Tennessee. Keeping with tradition, the meeting was held in conjunction with the Fall meeting of the APS Division of Nuclear Physics. Approximately 90 physicists participated in the meeting, presenting 25 talks in seven plenary sessions and 48 talks in 11 parallel sessions. These sessions covered a wide range of topics related to strongly interacting matter. Among these were charm spectroscopy, gluonic exotics, nucleon resonance physics, RHIC physics, electroweak and spin physics, lattice QCD initiatives, and new facilities. Brad Tippens and Brad Keister provided perspective from the funding agencies. The organisers are extremely grateful to the following institutions for financial and logistical support: the American Physical Society, Jefferson Lab, Brookhaven National Laboratory, and Vanderbilt University. We thank the following persons for assisting in organising the parallel sessions: Ted Barnes, Jian-Ping Chen, Ed Kinney, Krishna Kumar, Harry Lee, Mike Leitch, Kam Seth, and Dennis Weygand. We also thank Gerald Ragghianti for designing the conference poster, Will Johns for managing the audio-visual equipment and for placing the talks on the web, Sandy Childress for administrative expertise, and Vanderbilt graduate students Eduardo Luiggi and Jesus Escamillad for their assistance. David Ernst, Kees de Jager, Craig Roberts (Chair), Paul Sheldon and Eric Swanson Editors

  5. Proceedings of the 1992 topical meeting on advances in reactor physics. Volume 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-04-01

    This document, Volume 2, presents proceedings of the 1992 Topical Meeting on Advances in Reactor Physics on March 8--11, 1992 at Charleston, SC. Session topics were as follows: Transport Theory; Fast Reactors; Plant Analyzers; Integral Experiments/Measurements & Analysis; Core Computational Systems; Reactor Physics; Monte Carlo; Safety Aspects of Heavy Water Reactors; and Space-Time Core Kinetics. The individual reports have been cataloged separately. (FI)

  6. Report of a Meeting on Contemporary Topics in Zebrafish Husbandry and Care.

    PubMed

    Osborne, Nikki; Paull, Gregory; Grierson, Adam; Dunford, Karen; Busch-Nentwich, Elisabeth M; Sneddon, Lynne U; Wren, Natalie; Higgins, Joe; Hawkins, Penny

    2016-12-01

    A meeting on Contemporary Topics in Zebrafish Husbandry and Care was held in the United Kingdom in 2014, with the aim of providing a discussion forum for researchers, animal technologists, and veterinarians from academia and industry to share good practice and exchange ideas. Presentation topics included protocols for optimal larval rearing, implementing the 3Rs (replacement, reduction, and refinement) in large-scale colony management, and environmental enrichment. The audience also participated in a survey of current practice relating to practical husbandry, cryopreservation, and the provision of enrichment.

  7. Report of a Meeting on Contemporary Topics in Zebrafish Husbandry and Care

    PubMed Central

    Osborne, Nikki; Paull, Gregory; Grierson, Adam; Dunford, Karen; Busch-Nentwich, Elisabeth M.; Sneddon, Lynne U.; Wren, Natalie; Higgins, Joe

    2016-01-01

    Abstract A meeting on Contemporary Topics in Zebrafish Husbandry and Care was held in the United Kingdom in 2014, with the aim of providing a discussion forum for researchers, animal technologists, and veterinarians from academia and industry to share good practice and exchange ideas. Presentation topics included protocols for optimal larval rearing, implementing the 3Rs (replacement, reduction, and refinement) in large-scale colony management, and environmental enrichment. The audience also participated in a survey of current practice relating to practical husbandry, cryopreservation, and the provision of enrichment. PMID:27537782

  8. Building an Ethical Community in the Classroom: Community Meeting.

    ERIC Educational Resources Information Center

    McClurg, Lois Gail

    1998-01-01

    Describes "community meetings" in early childhood classrooms, designed to create an intentional community devoted to learning to live with and consider the perspectives of others. Discusses how meetings work, community meeting and the topic of exclusion, students' learning about themselves, awareness as a kind of solution, airing a…

  9. Research on Estrogen and Behavior Is a "Hot Topic" at the 2011 Society for Neuroscience Meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Biegon, Anat

    The Society for Neuroscience has selected recent research on estrogen and its effect on behavior conducted at BNL for its "hot topics" book distributed to reporters attending the society's 2011 meeting in Washington, D.C., November 12-16.

  10. Research on Estrogen and Behavior Is a "Hot Topic" at the 2011 Society for Neuroscience Meeting

    ScienceCinema

    Biegon, Anat

    2018-05-30

    The Society for Neuroscience has selected recent research on estrogen and its effect on behavior conducted at BNL for its "hot topics" book distributed to reporters attending the society's 2011 meeting in Washington, D.C., November 12-16.

  11. 76 FR 38409 - Notice of an Open Meeting of the Advisory Committee on Water Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ... DEPARTMENT OF THE INTERIOR Notice of an Open Meeting of the Advisory Committee on Water... Committee on Water Information (ACWI). SUMMARY: Notice is hereby given of a meeting of the ACWI. This meeting is to discuss broad policy-related topics relating to national water initiatives, and the...

  12. The History of the APS Topical Group on Shock Compression of Condensed Matter

    NASA Astrophysics Data System (ADS)

    Forbes, Jerry W.

    2002-07-01

    In order to provide broader scientific recognition and to advance the science of shock compressed condensed matter, a group of American Physical Society (APS) members worked within the Society to make this field an active part of the APS. Individual papers were presented at APS meetings starting in the 1940's and shock wave sessions were organized starting with the 1967 Pasadena meeting. Shock wave topical conferences began in 1979 in Pullman, WA. Signatures were obtained on a petition in 1984 from a balanced cross-section of the shock wave community to form an APS Topical Group (TG). The APS Council officially accepted the formation of the Shock Compression of Condensed Matter (SCCM) TG at its October 1984 meeting. This action firmly aligned the shock wave field with a major physical science organization. Most early topical conferences were sanctioned by the APS while those held after 1992 were official APS meetings. The topical group organizes a shock wave topical conference in odd numbered years while participating in shock wave/high pressure sessions at APS general meetings in even numbered years.

  13. AGU Panel meets on career topics

    NASA Astrophysics Data System (ADS)

    Hollister, Charles

    Graduate students and their career opportunities in ocean and earth sciences were the focus of the Education and Human Resources (E & HR) Committee meeting held at the 1982 AGU Fall Meeting in San Francisco. A standing committee of AGU, the E & HR committee is responsible for matters concerning education in earth, ocean, and planetary sciences from precollege through graduate programs, including career guidance, academic preparation, student recruitment, and manpower supply and demand.At the meeting a draft of the AGU-sponsored Careers in Oceanography booklet by committee chairman C. Hollister was thoroughly discussed and a new draft will emerge soon for final approval. The booklet is designed to complement the Careers in Geophysics booklet recently published by AGU; the booklets contain information about planning a career, job opportunities, educational requirements, and a synopsis of where the prospective student might apply.

  14. The History of the APS Shock Compression of Condensed Matter Topical Group

    NASA Astrophysics Data System (ADS)

    Forbes, Jerry W.

    2001-06-01

    To provide broader scientific recognition and to advance the science of shock-compressed condensed matter, a group of APS members worked within the Society to make this technical field an active part of APS. Individual papers were given at APS meetings starting in the 1950’s and then later whole sessions were organized starting at the 1967 Pasadena meeting. Topical conferences began in 1979 in Pullman, WA where George Duvall and Dennis Hayes were co-chairs. Most all early topical conferences were sanctioned by the APS while those held after 1985 were official APS meetings. In 1984, after consulting with a number of people in the shock wave field, Robert Graham circulated a petition to form an APS topical group. He obtained signatures from a balanced cross-section of the community. William Havens, the executive secretary of APS, informed Robert Graham by letter on November 28, 1984 that the APS Council had officially accepted the formation of this topical group at its October 28, 1984 meeting. The first election occurred July 23, 1985 where Robert Graham was elected chairman, William Nellis vice-chairman, and Jerry Forbes secretary/treasurer. The topical group remains viable today by holding a topical conference in odd numbered years and shock wave sessions at APS general meetings in even numbered years A major benefit of being an official unit of APS is the allotment of APS fellows every year. The APS shock compression award established in 1987, has also provided broad recognition of many major scientific accomplishments in this field.

  15. Topical meeting on optical interference coatings (OIC'2001): manufacturing problem.

    PubMed

    Dobrowolski, J A; Browning, Stephen; Jacobson, Michael; Nadal, Maria

    2002-06-01

    Measurements are presented of the experimental filters submitted to the first optical thin-film manufacturing problem posed in conjunction with the Topical Meeting on Optical Interference Coatings, in which the object was to produce multilayers with spectral transmittance and reflectance curves that were as close as possible to the target values that were specified in the 400- to 600-nm spectral region. No limit was set on the overall thickness of the solutions or the number of layers used in their construction. The participants were free to use the coating materials of their choice. Six different groups submitted a total of 11 different filters for evaluation. Three different physical vapor deposition processes were used for the manufacture of the coatings: magnetron sputtering, ion-beam sputtering, and plasma-ion-assisted, electron-beam gun evaporation. The solutions ranged in metric thickness from 758 to 4226 nm and consisted of between 8 and 27 layers. For all but two of the samples submitted, the average rms departure of the measured transmittances and reflectances from the target values in the spectral region of interest was between 0.98% and 1.55%.

  16. 'Hot Topics' in Astrophysics

    NASA Technical Reports Server (NTRS)

    Maran, Stephen P.

    2000-01-01

    Three current topics in astrophysics are described here on the occasion of the joint meeting of the American Association of Physics Teachers and the American Astronomical Society (Jan. 7-11, 2001, San Diego, Calif.). Many equally exciting topics--ranging from the dozens of newly discovered planets of sunlike stars to evidence suggesting that the expansion of the universe is accelerating--could have been chosen. The topics discussed are: (1) the habitability of Mars, (2) black holes, galaxy bulges, and the X-ray background, and (3) the greatest explosions since the Big Bang.

  17. Topics in Biomedical Optics: Introduction

    NASA Astrophysics Data System (ADS)

    Hebden, Jeremy C.; Boas, David A.; George, John S.; Durkin, Anthony J.

    2003-06-01

    The field of biomedical optics is experiencing tremendous growth. Biomedical technologies contribute in the creation of devices used in healthcare of various specialties (ophthalmology, cardiology, anesthesiology, and immunology, etc.). Recent research in biomedical optics is discussed. Overviews of meetings held at the 2002 Optical Society of America Biomedical Topical Meetings are presented.

  18. Meeting report for "OddPols" 2014: the odds invite an even.

    PubMed

    Roy-Engel, Astrid M

    2015-02-01

    The Ninth International Biennial Conference on RNA Polymerases I and III (the "OddPols") was held on June 19-21, 2014 at the University of Michigan, Ann Arbor, USA. Sponsored by New England Biolabs, the Cayman Chemical Company, the Rackham Graduate School and the University of Michigan Health System, and organized by David Engelke, Craig Pikaard, Lawrence Rothblum, Andrzej Wierzbicki and Astrid Engel. This year at the conference, the "odds" were increased by expanding the usual topics on the advances in RNA polymerases I and III research to include presentations on RNA polymerase IV and V. The keynote speaker, Craig Pikaard, opened the meeting with his presentation entitled "Five nuclear multisubunit RNA polymerases". The meeting drew attendees from fourteen countries that shared their research discoveries through oral and poster presentations. The talks were organized into 11 sessions covering seven distinct topics. Here we present some of the highlights from the meeting using summaries provided by the participants. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Dapsone for topical use in extemporaneous preparations.

    PubMed

    Wohlrab, Johannes; Michael, Julia

    2018-01-01

    The sulfone dapsone has an established role in systemic therapy. Its pharmacological and toxicological properties are well known. Topically, dapsone is used in a gel formulation for the treatment of acne vulgaris. In addition, there have been individual case reports on the efficacy of topical dapsone preparations in the treatment of various neutrophilic dermatoses. To date, no finished medicinal product for topical use has been available in Germany. Against this background, we set out to develop extemporaneous preparations containing dapsone (5 %) that meet the quality requirements of the European Pharmacopoeia as well as the manufacturing requirements of the German Ordinance on the Operation of Pharmacies (ApBetrO). These formulations included the incorporation of dapsone in a hydrophobic cream base ("hydrophobe Basiscreme DAC") as well as in methylprednisolone aceponate 0.1 % ointment (alternatively, in the latter's cream base without active ingredient). Tests aimed at investigating the physical, chemical, and microbiological stability of these formulations showed them to meet the aforementioned quality requirements. The extemporaneous formulations presented herein broaden the therapeutic options for topical treatment, in particular for patients with chronic inflammatory dermatoses associated with a neutrophilic pathogenesis. © 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  20. Highlights of the ASPE 2004 Winter Topical Meeting on Free-Form Optics: Design, Fabrication, Metrology, Assembly

    NASA Technical Reports Server (NTRS)

    Ohl, Raymond G.; Dow, Thomas A.; Sohn, alex

    2004-01-01

    We present highlights from the American Society for Precision Engineering's 2004 winter topical meeting entitled Free-Form Optics: Design, Fabrication, Metrology, Assembly. We emphasize those papers that are most relevant to astronomical optics. Optical surfaces that transcend the bounds of rotational symmetry have been implemented in novel optical systems with fantastic results since the release of Polaroid's first instant camera. Despite these successes, free-form optics have found only a few niche applications and have yet to enter the mainstream. The purpose of this meeting is to identify the state of the art of free-form optics design, fabrication, metrology and assembly and to identify the technical and logistical challenges that inhibit their widespread use. Issues that will be addressed include: What are free-form optics? How can optical systems be made better with free-form optics? How can designers use free-form optics? How can free-form optics be fabricated? How can they be measured? How are free-form optical systems assembled? Control of multi-axis systems.

  1. A heuristic approach to determine an appropriate number of topics in topic modeling

    PubMed Central

    2015-01-01

    Background Topic modelling is an active research field in machine learning. While mainly used to build models from unstructured textual data, it offers an effective means of data mining where samples represent documents, and different biological endpoints or omics data represent words. Latent Dirichlet Allocation (LDA) is the most commonly used topic modelling method across a wide number of technical fields. However, model development can be arduous and tedious, and requires burdensome and systematic sensitivity studies in order to find the best set of model parameters. Often, time-consuming subjective evaluations are needed to compare models. Currently, research has yielded no easy way to choose the proper number of topics in a model beyond a major iterative approach. Methods and results Based on analysis of variation of statistical perplexity during topic modelling, a heuristic approach is proposed in this study to estimate the most appropriate number of topics. Specifically, the rate of perplexity change (RPC) as a function of numbers of topics is proposed as a suitable selector. We test the stability and effectiveness of the proposed method for three markedly different types of grounded-truth datasets: Salmonella next generation sequencing, pharmacological side effects, and textual abstracts on computational biology and bioinformatics (TCBB) from PubMed. Conclusion The proposed RPC-based method is demonstrated to choose the best number of topics in three numerical experiments of widely different data types, and for databases of very different sizes. The work required was markedly less arduous than if full systematic sensitivity studies had been carried out with number of topics as a parameter. We understand that additional investigation is needed to substantiate the method's theoretical basis, and to establish its generalizability in terms of dataset characteristics. PMID:26424364

  2. CONFERENCE NOTE: European Optical Society, Topical Meeting Optical Metrology and Nanotechnology, Engelberg, Switzerland, 27 30 March 1994

    NASA Astrophysics Data System (ADS)

    1993-01-01

    This meeting, organized by the Paul Scherrer Institute's Department of Applied Solid State Physics, will be held from 27 30 March 1994 at the Hotel Regina-Titlis, Engelberg, Switzerland. The aim is to bring together scientists from two important fields of current research and increasing industrial relevance. Optical metrology is a traditional discipline of applied optics which reached the nanometre scale a long time ago. Nanotechnology is setting new limits and represents a major challenge to metrology, as well as offering new opportunities to optics. The meeting is intended to help define a common future for optical metrology and nanotechnology. Topics to be covered include: nanometre position control and measuring techniques ultrahigh precision interferometry scanning probe microscopy (AFM, SNOM, etc.) surface modification by scanning probe methods precision surface fabrication and characterization nanolithography micro-optics, diffractive optics components, including systems and applications subwavelength optical structures synthetic optical materials structures and technologies for X-ray optics. For further information please contact: Jens Gobrecht (Secretary), Paul Scherrer Institute, CH-5232 Villigen-PSI, Switzerland.Tel. (41)56992529; Fax (41) 5698 2635.

  3. Dogmas and controversies in compression therapy: report of an International Compression Club (ICC) meeting, Brussels, May 2011.

    PubMed

    Flour, Mieke; Clark, Michael; Partsch, Hugo; Mosti, Giovanni; Uhl, Jean-Francois; Chauveau, Michel; Cros, Francois; Gelade, Pierre; Bender, Dean; Andriessen, Anneke; Schuren, Jan; Cornu-Thenard, André; Arkans, Ed; Milic, Dragan; Benigni, Jean-Patrick; Damstra, Robert; Szolnoky, Gyozo; Schingale, Franz

    2013-10-01

    The International Compression Club (ICC) is a partnership between academics, clinicians and industry focused upon understanding the role of compression in the management of different clinical conditions. The ICC meet regularly and from these meetings have produced a series of eight consensus publications upon topics ranging from evidence-based compression to compression trials for arm lymphoedema. All of the current consensus documents can be accessed on the ICC website (http://www.icc-compressionclub.com/index.php). In May 2011, the ICC met in Brussels during the European Wound Management Association (EWMA) annual conference. With almost 50 members in attendance, the day-long ICC meeting challenged a series of dogmas and myths that exist when considering compression therapies. In preparation for a discussion on beliefs surrounding compression, a forum was established on the ICC website where presenters were able to display a summary of their thoughts upon each dogma to be discussed during the meeting. Members of the ICC could then provide comments on each topic thereby widening the discussion to the entire membership of the ICC rather than simply those who were attending the EWMA conference. This article presents an extended report of the issues that were discussed, with each dogma covered in a separate section. The ICC discussed 12 'dogmas' with areas 1 through 7 dedicated to materials and application techniques used to apply compression with the remaining topics (8 through 12) related to the indications for using compression. © 2012 The Authors. International Wound Journal © 2012 John Wiley & Sons Ltd and Medicalhelplines.com Inc.

  4. EDITORIAL The 23rd Nordic Semiconductor Meeting The 23rd Nordic Semiconductor Meeting

    NASA Astrophysics Data System (ADS)

    Ólafsson, Sveinn; Sveinbjörnsson, Einar

    2010-12-01

    A Nordic Semiconductor Meeting is held every other year with the venue rotating amongst the Nordic countries of Denmark, Finland, Iceland, Norway and Sweden. The focus of these meetings remains 'original research and science being carried out on semiconductor materials, devices and systems'. Reports on industrial activity have usually featured. The topics have ranged from fundamental research on point defects in a semiconductor to system architecture of semiconductor electronic devices. Proceedings from these events are regularly published as a topical issue of Physica Scripta. All of the papers in this topical issue have undergone critical peer review and we wish to thank the reviewers and the authors for their cooperation, which has been instrumental in meeting the high scientific standards and quality of the series. This meeting of the 23rd Nordic Semiconductor community, NSM 2009, was held at Háskólatorg at the campus of the University of Iceland, Reykjavik, Iceland, 14-17 June 2009. Support was provided by the University of Iceland. Almost 50 participants presented a broad range of topics covering semiconductor materials and devices as well as related material science interests. The conference provided a forum for Nordic and international scientists to present and discuss new results and ideas concerning the fundamentals and applications of semiconductor materials. The meeting aim was to advance the progress of Nordic science and thus aid in future worldwide technological advances concerning technology, education, energy and the environment. Topics Theory and fundamental physics of semiconductors Emerging semiconductor technologies (for example III-V integration on Si, novel Si devices, graphene) Energy and semiconductors Optical phenomena and optical devices MEMS and sensors Program 14 June Registration 13:00-17:00 15 June Meeting program 09:30-17:00 and Poster Session I 16 June Meeting program 09:30-17:00 and Poster Session II 17 June Excursion and dinner

  5. Topical antifungal agents: an update.

    PubMed

    Diehl, K B

    1996-10-01

    So many topical antifungal agents have been introduced that it has become very difficult to select the proper agent for a given infection. Nonspecific agents have been available for many years, and they are still effective in many situations. These agents include Whitfield's ointment, Castellani paint, gentian violet, potassium permanganate, undecylenic acid and selenium sulfide. Specific antifungal agents include, among others, the polyenes (nystatin, amphotericin B), the imidazoles (metronidazole, clotrimazole) and the allylamines (terbinafine, naftifine). Although the choice of an antifungal agent should be based on an accurate diagnosis, many clinicians believe that topical miconazole is a relatively effective agent for the treatment of most mycotic infections. Terbinafine and other newer drugs have primary fungicidal effects. Compared with older antifungal agents, these newer drugs can be used in lower concentrations and shorter therapeutic courses. Studies are needed to evaluate the clinical efficacies and cost advantages of both newer and traditional agents.

  6. 77 FR 60430 - Meeting of the Mobile Sources Technical Review Subcommittee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9736-3] Meeting of the Mobile Sources Technical Review... Advisory Committee Act, Public Law 92- 463, notice is hereby given that the Mobile Sources Technical Review... Advisory Committee. This is an open meeting. The meeting will include discussion of current topics and...

  7. Eigenspace-based fuzzy c-means for sensing trending topics in Twitter

    NASA Astrophysics Data System (ADS)

    Muliawati, T.; Murfi, H.

    2017-07-01

    As the information and communication technology are developed, the fulfillment of information can be obtained through social media, like Twitter. The enormous number of internet users has triggered fast and large data flow, thus making the manual analysis is difficult or even impossible. An automated methods for data analysis is needed, one of which is the topic detection and tracking. An alternative method other than latent Dirichlet allocation (LDA) is a soft clustering approach using Fuzzy C-Means (FCM). FCM meets the assumption that a document may consist of several topics. However, FCM works well in low-dimensional data but fails in high-dimensional data. Therefore, we propose an approach where FCM works on low-dimensional data by reducing the data using singular value decomposition (SVD). Our simulations show that this approach gives better accuracies in term of topic recall than LDA for sensing trending topic in Twitter about an event.

  8. Bioinformatics Meets Virology: The European Virus Bioinformatics Center's Second Annual Meeting.

    PubMed

    Ibrahim, Bashar; Arkhipova, Ksenia; Andeweg, Arno C; Posada-Céspedes, Susana; Enault, François; Gruber, Arthur; Koonin, Eugene V; Kupczok, Anne; Lemey, Philippe; McHardy, Alice C; McMahon, Dino P; Pickett, Brett E; Robertson, David L; Scheuermann, Richard H; Zhernakova, Alexandra; Zwart, Mark P; Schönhuth, Alexander; Dutilh, Bas E; Marz, Manja

    2018-05-14

    The Second Annual Meeting of the European Virus Bioinformatics Center (EVBC), held in Utrecht, Netherlands, focused on computational approaches in virology, with topics including (but not limited to) virus discovery, diagnostics, (meta-)genomics, modeling, epidemiology, molecular structure, evolution, and viral ecology. The goals of the Second Annual Meeting were threefold: (i) to bring together virologists and bioinformaticians from across the academic, industrial, professional, and training sectors to share best practice; (ii) to provide a meaningful and interactive scientific environment to promote discussion and collaboration between students, postdoctoral fellows, and both new and established investigators; (iii) to inspire and suggest new research directions and questions. Approximately 120 researchers from around the world attended the Second Annual Meeting of the EVBC this year, including 15 renowned international speakers. This report presents an overview of new developments and novel research findings that emerged during the meeting.

  9. MeetingVis: Visual Narratives to Assist in Recalling Meeting Context and Content.

    PubMed

    Shi, Yang; Bryan, Chris; Bhamidipati, Sridatt; Zhao, Ying; Zhang, Yaoxue; Ma, Kwan-Liu

    2018-06-01

    In team-based workplaces, reviewing and reflecting on the content from a previously held meeting can lead to better planning and preparation. However, ineffective meeting summaries can impair this process, especially when participants have difficulty remembering what was said and what its context was. To assist with this process, we introduce MeetingVis, a visual narrative-based approach to meeting summarization. MeetingVis is composed of two primary components: (1) a data pipeline that processes the spoken audio from a group discussion, and (2) a visual-based interface that efficiently displays the summarized content. To design MeetingVis, we create a taxonomy of relevant meeting data points, identifying salient elements to promote recall and reflection. These are mapped to an augmented storyline visualization, which combines the display of participant activities, topic evolutions, and task assignments. For evaluation, we conduct a qualitative user study with five groups. Feedback from the study indicates that MeetingVis effectively triggers the recall of subtle details from prior meetings: all study participants were able to remember new details, points, and tasks compared to an unaided, memory-only baseline. This visual-based approaches can also potentially enhance the productivity of both individuals and the whole team.

  10. 9th Transgenic Technology Meeting (TT2010) in Berlin, Germany: a meeting report.

    PubMed

    Saunders, Thomas L; Sobieszczuk, Peter

    2010-12-01

    The first Transgenic Technology (TT) Meeting was organized in 1999 by Johannes Wilbertz, Karolinska Institute, Stockholm, Sweden as a regional meeting. The TT Meetings continued in this way, constantly gathering additional practitioners of transgenic methodologies until the breakthrough in 2005 when the 6th TT Meeting in Barcelona, Spain, hosted by Lluis Montoliu (Centro Nacional de Biotecnologia, Madrid, Spain), generated the momentum to establish the International Society for Transgenic Technologies (ISTT). Since 2006, the ISTT has continued to promote the TT Meetings and provide its membership with a forum to discuss best practices and new methods in the field. The TT2010 Meeting was held at the Max Delbrück Center for Molecular Medicine (Berlin, Germany). Participation at the TT2010 Meeting exceeded the registration capacity and set a new attendance record. Session topics included methods for the generation of rat and mouse models of human disease, fundamental and advanced topics in rodent embryonic stem cells, and the newest transgenic technologies. Short presentations from selected abstracts were of especial interest. Roundtable discussions on transgenic facility establishment and cryoarchiving of mouse lines were favorably received. Students, technical staff, and professors participated in numerous discussions and came away with practical methods and new ideas for research.

  11. 78 FR 7460 - Stakeholder Meeting on the Nationally Recognized Testing Laboratory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... Laboratory (NRTL) Program policies. The meeting will focus on the following topics: NRTL independence; the... as time permits, other topics raised by participants or OSHA staff. OSHA plans to use the information..., in writing, suggestions of additional topics for the meeting is Wednesday, February 13, 2013...

  12. EDITORIAL: Special section: Selected papers from OMS'05, the 1st Topical Meeting of the European Optical Society on Optical Microsystems (OMS)

    NASA Astrophysics Data System (ADS)

    Rendina, Ivo; Fazio, Eugenio; Ferraro, Pietro

    2006-07-01

    OMS'05 is the first international conference wholly dedicated to optical microsystems. It was organized by the European Optical Society (EOS) in the frame of its international topical meeting activity and was held in Italy, September 2005, amidst the wonderful scenery of the Island of Capri. A possible definition of an optical microsystem is a complex system, able to perform one or more sensing and actuation functions, where optical devices are integrated in a smart way with electronic, mechanical and sensing components by taking advantage of the progress in micro- and nano-technologies. The increasing interest in this field arises from the expected applications that would significantly improve the quality of life. The list of possibilities offered by the optical microsystem enabling technologies is very long and seems to increase day by day. We are not only thinking about the next generation of optical telecommunication networks and computers, but also about low-cost, compact microsystems for environmental monitoring, in order to improve safety in the avionic and automotive fields, medical diagnostics and proteomic/genomic studies, or just finding general applications in several industrial fields. The goal of the conference was to involve scientists and young researchers from the main public and private laboratories, giving them the opportunity to present new scientific results and compare their know-how in the exciting and emerging field of optical microsystems. We believe that we succeeded in this. More than 200 scientists from all over the world attended the conference. We had more than 100 oral presentations and approximately 20 from the keynote lectures and invited speeches. It was an opportunity to define the most recent progress carried out in the field and to outline the possible road-map leading to the expected results in the industrial and social fields. We strongly believe that research and technology are closely interconnected at present and cannot

  13. 78 FR 54238 - President's Export Council; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-03

    ... DEPARTMENT OF COMMERCE International Trade Administration President's Export Council; Meeting... meeting. SUMMARY: The President's Export Council will hold a meeting to deliberate on recommendations related to promoting the expansion of U.S. exports. Topics may include trade promotion authority...

  14. An overview of topic modeling and its current applications in bioinformatics.

    PubMed

    Liu, Lin; Tang, Lin; Dong, Wen; Yao, Shaowen; Zhou, Wei

    2016-01-01

    With the rapid accumulation of biological datasets, machine learning methods designed to automate data analysis are urgently needed. In recent years, so-called topic models that originated from the field of natural language processing have been receiving much attention in bioinformatics because of their interpretability. Our aim was to review the application and development of topic models for bioinformatics. This paper starts with the description of a topic model, with a focus on the understanding of topic modeling. A general outline is provided on how to build an application in a topic model and how to develop a topic model. Meanwhile, the literature on application of topic models to biological data was searched and analyzed in depth. According to the types of models and the analogy between the concept of document-topic-word and a biological object (as well as the tasks of a topic model), we categorized the related studies and provided an outlook on the use of topic models for the development of bioinformatics applications. Topic modeling is a useful method (in contrast to the traditional means of data reduction in bioinformatics) and enhances researchers' ability to interpret biological information. Nevertheless, due to the lack of topic models optimized for specific biological data, the studies on topic modeling in biological data still have a long and challenging road ahead. We believe that topic models are a promising method for various applications in bioinformatics research.

  15. Committee ARM User Executive Committee Meeting Summary March 30-31, 2016

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    This meeting was held at the National Center for Atmospheric Research (NCAR) Mesa Lab, Boulder, Colorado. Atmospheric Radiation Measurement (ARM) Climate Research Facility User Executive Committee (UEC) members present were: Chuck Long, Ernie Lewis, Larry Berg, Hailong Wang, Matt Shupe, Andrew Gettelman, and Dave Turner. Rob Wood joined the discussion at several points via conference call, as he was unable to attend in person. Gannet Hallar and Pavlos Kollias were unable to attend. ARM Infrastructure members present were: Jim Mather, Jennifer Comstock, Jimmy Voyles, Ken Kehoe, Doug Sisterson, Hanna Goss, and Giri Prakash. The ARM UEC met face to facemore » for the first time since the committee was formed in December, 2014 at the NCAR Mesa Lab in Boulder. Prior to this point, all UEC meetings were done via telephone, usually with the aid of collaboration software (e.g., Lync, GoToMeeting) allowing the entire committee to see a common presentation. These conference calls covered a wide range of topics, many of them on a recurrent basis; however, since the calls were limited to less than 90 minutes it was felt that a more dedicated meeting would allow us to delve more deeply into some of these topics. Three topics for this meeting came from previous conference call discussions: (1) data quality, (2) uncertainty quantification, and (3) improved communications. Two other topics were discussed during this meeting: (4) an overview of the LES (large-eddy simulation) ARM Symbiotic Simulation and Observation (LASSO) project and (5) the process for electing new UEC members. Summaries of each of these topics are provided below, along with recommendations that the UEC feels should be considered by the ARM Facility (which will be highlighted using italics).« less

  16. Meetings in Academe: It's Time for an "EXTREME MEETING MAKEOVER!"

    ERIC Educational Resources Information Center

    Berk, Ronald A.

    2012-01-01

    Meetings have a bad reputation with faculty. Rarely does one hear a positive word uttered about an upcoming or past meeting. That reputation has metastasized throughout higher education. The primary reason is because meetings can be major time wasters, accomplishing very little, often deteriorating into just another social event, or they may be…

  17. A Prerecognition Model for Hot Topic Discovery Based on Microblogging Data

    PubMed Central

    Zhu, Tongyu

    2014-01-01

    The microblogging is prevailing since its easy and anonymous information sharing at Internet, which also brings the issue of dispersing negative topics, or even rumors. Many researchers have focused on how to find and trace emerging topics for analysis. When adopting topic detection and tracking techniques to find hot topics with streamed microblogging data, it will meet obstacles like streamed microblogging data clustering, topic hotness definition, and emerging hot topic discovery. This paper schemes a novel prerecognition model for hot topic discovery. In this model, the concepts of the topic life cycle, the hot velocity, and the hot acceleration are promoted to calculate the change of topic hotness, which aims to discover those emerging hot topics before they boost and break out. Our experiments show that this new model would help to discover potential hot topics efficiently and achieve considerable performance. PMID:25254235

  18. A prerecognition model for hot topic discovery based on microblogging data.

    PubMed

    Zhu, Tongyu; Yu, Jianjun

    2014-01-01

    The microblogging is prevailing since its easy and anonymous information sharing at Internet, which also brings the issue of dispersing negative topics, or even rumors. Many researchers have focused on how to find and trace emerging topics for analysis. When adopting topic detection and tracking techniques to find hot topics with streamed microblogging data, it will meet obstacles like streamed microblogging data clustering, topic hotness definition, and emerging hot topic discovery. This paper schemes a novel prerecognition model for hot topic discovery. In this model, the concepts of the topic life cycle, the hot velocity, and the hot acceleration are promoted to calculate the change of topic hotness, which aims to discover those emerging hot topics before they boost and break out. Our experiments show that this new model would help to discover potential hot topics efficiently and achieve considerable performance.

  19. 78 FR 54248 - SFIREG Full Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-03

    .... SUMMARY: The Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and... for the meeting and sets forth the tentative agenda topics. DATES: The meeting will be held on Monday...://www.epa.gov/dockets . II. Tentative Agenda Topics 1. OPP update on methomyl. 2. OECA update on...

  20. 75 FR 18512 - National Institute of Mental Health; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... U.S.C. App.), notice is hereby given of an Interagency Autism Coordinating Committee (IACC) meeting... several presentations on a variety of topics: the Autism Treatment Network, changes in the DSM-V related to autism, stem cell research, non-verbal autism and comparative effectiveness research. The meeting...

  1. 76 FR 12960 - SFIREG Environmental Quality Issues Working Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ... Research and Evaluation Group (SFIREG), Environmental Quality Issues (EQI) Working Committee will hold a 2... and times for the meeting and sets forth the tentative agenda topics. DATES: The meeting will be held... telephone number is (703) 305-5805. II. Tentative Agenda Topics Topics to be discussed may include, but are...

  2. Parent Group Guide: Topics for Families of Young Children with Handicaps.

    ERIC Educational Resources Information Center

    Gerlock, Elizabeth F., Ed.; And Others.

    Developed as part of the Family, Infant, and Toddler Project, and intended as a guide for parent groups, the document focuses on such topics as instruction, child development, and family concerns related to children with handicaps. Individual topic guides provide information on ways to begin the parent group meeting, information to consider,…

  3. 75 FR 52328 - SFIREG Full Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-25

    ... Association of American Pesticide Control Officials (AAPCO), State FIFRA Issues Research and Evaluation Group... topics. DATES: The meeting will be held on Monday, September 20, 2010, from 8:30 a.m. to 5 p.m. To... topics for the meeting. 1. Transitioning insect repellents from, section 25(b) to section 3 status. 2...

  4. 77 FR 59396 - SFIREG EQI Working Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-27

    ... Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group... the meeting and sets forth the tentative agenda topics. DATES: The meeting will be held on Monday... docket available at http://www.epa.gov/dockets . II. Tentative Agenda Topics 1. Persistent herbicide...

  5. 77 FR 22800 - Notice of Public Meeting, Dakotas Resource Advisory Council Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... meetings, topics will include: North and South Dakota Field Office manager updates, briefings by council.... M. Elaine Raper, Dakotas District Manager, Eastern Montana. [FR Doc. 2012-9207 Filed 4-16-12; 8:45...

  6. Longitudinal Gender Disparity in Female Urology Resident Primary Authorship at an American Urological Association Sectional Meeting.

    PubMed

    Lin, Tony R; Kocher, Neil J; Klausner, Adam P; Raman, Jay D

    2017-12-01

    To further evaluate the academic representation of female urology residents in the United States, we reviewed abstracts from the Mid-Atlantic American Urological Association (MA-AUA) sectional meetings to determine if the recent increase in the number of female urology residents mirrored an increase in this group's abstract authorship. Full text abstracts from the MA-AUA meetings were analyzed from 2008 to 2014 excluding 1 joint section meeting. First-author gender was determined by querying publicly available institutional websites, social media platforms, and the U.S. News & World Report. First-author gender was indeterminable in 10 abstracts based on search criteria and these were excluded. Individual abstracts were broadly categorized based on keywords into 1 of several topics. Chi-square statistical tests examined the relationship between first-authorship gender, publication year, and abstract category. The number of female urology residents in the MA-AUA increased over the study period. A total of 484 abstracts were analyzed. Three hundred ninety-three abstracts (81%) included a male first-author, whereas 81 abstracts (17%) included a female first-author. Female first-authorship ranged from 13% to 25% annually. Comparison of male-to-female first-authorship was statistically significant in all years evaluated (P <.001). There was a statistically significant difference between male and female first-authorship in all topic categories (P <.01), except Education/Other (P = .56). Despite continued gains and increasing female representation in urology, these data highlight significantly fewer female first-authors at the regional Mid-Atlantic section meetings. Larger studies are necessary to identify contributing factors and further areas for improvement toward decreasing gender imbalances within the academic community. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. It's Elementary: Special Topics in Elementary Education.

    ERIC Educational Resources Information Center

    Crawford, Patricia A., Ed.; Burriss, Kathleen Glascott, Ed.

    As elementary teachers work to educate and meet the needs of the students in their care, their job has become increasingly challenging and demanding. This volume addresses a variety of issues and topics related to elementary education around eight sectional themes relevant to the work of elementary teachers: celebrating diversity, classroom…

  8. TEDD Annual Meeting with 3D Bioprinting Workshop.

    PubMed

    Raghunath, Michael; Rimann, Markus; Kopanska, Katarzyna S; Laternser, Sandra

    2018-02-01

    Bioprinting is the technology of choice for realizing functional tissues such as vascular system, muscle, cartilage and bone. In the future, bioprinting will influence the way we engineer tissues and bring it to a new level of physiological relevance. That was the topic of the 2017 TEDD Annual Meeting at ZHAW Waedenswil on 8th and 9th November. In an exciting workshop, the two companies regenHU Ltd. and CELLINK gave us an insight into highly topical applications and collaborations in this domain.

  9. Correlation between MCAT biology content specifications and topic scope and sequence of general education college biology textbooks.

    PubMed

    Rissing, Steven W

    2013-01-01

    Most American colleges and universities offer gateway biology courses to meet the needs of three undergraduate audiences: biology and related science majors, many of whom will become biomedical researchers; premedical students meeting medical school requirements and preparing for the Medical College Admissions Test (MCAT); and students completing general education (GE) graduation requirements. Biology textbooks for these three audiences present a topic scope and sequence that correlates with the topic scope and importance ratings of the biology content specifications for the MCAT regardless of the intended audience. Texts for "nonmajors," GE courses appear derived directly from their publisher's majors text. Topic scope and sequence of GE texts reflect those of "their" majors text and, indirectly, the MCAT. MCAT term density of GE texts equals or exceeds that of their corresponding majors text. Most American universities require a GE curriculum to promote a core level of academic understanding among their graduates. This includes civic scientific literacy, recognized as an essential competence for the development of public policies in an increasingly scientific and technological world. Deriving GE biology and related science texts from majors texts designed to meet very different learning objectives may defeat the scientific literacy goals of most schools' GE curricula.

  10. Correlation between MCAT Biology Content Specifications and Topic Scope and Sequence of General Education College Biology Textbooks

    PubMed Central

    Rissing, Steven W.

    2013-01-01

    Most American colleges and universities offer gateway biology courses to meet the needs of three undergraduate audiences: biology and related science majors, many of whom will become biomedical researchers; premedical students meeting medical school requirements and preparing for the Medical College Admissions Test (MCAT); and students completing general education (GE) graduation requirements. Biology textbooks for these three audiences present a topic scope and sequence that correlates with the topic scope and importance ratings of the biology content specifications for the MCAT regardless of the intended audience. Texts for “nonmajors,” GE courses appear derived directly from their publisher's majors text. Topic scope and sequence of GE texts reflect those of “their” majors text and, indirectly, the MCAT. MCAT term density of GE texts equals or exceeds that of their corresponding majors text. Most American universities require a GE curriculum to promote a core level of academic understanding among their graduates. This includes civic scientific literacy, recognized as an essential competence for the development of public policies in an increasingly scientific and technological world. Deriving GE biology and related science texts from majors texts designed to meet very different learning objectives may defeat the scientific literacy goals of most schools’ GE curricula. PMID:24006392

  11. Conference report: hot topics in antibody-drug conjugate development.

    PubMed

    Thudium, Karen; Bilic, Sanela

    2013-12-01

    American Association of Pharmaceutical Scientists National Biotechnology Conference Sheraton San Diego Hotel and Marina, San Diego, CA, USA, 19-23 May 2013 The National Biotechnology Conference, is a premier meeting for biotechnology professionals covering a broad range of hot topics in the biotechnology industry. Attracting participants from academia, industry and regulatory, this meeting features sessions that aim to address emerging subjects of interest and allows for open exchange between scientists. The 2013 conference featured leading researchers in the fields of antibody-drug conjugates (ADCs) and immunogenicity. Herein, we present a summary of the ADC hot topics, including bioanalytical and PK considerations, quantitative evaluation of the impact of immunogenicity and ADME to understand ADC drug-drug interactions, and clinical considerations for ADC development. This article aims to summarize the recommendations that were made by the speakers during various sessions throughout the conference.

  12. 75 FR 19662 - Advisory Committee on Presidential Libraries Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on Presidential Libraries Meeting... Records Administration (NARA) announces a meeting of the Advisory Committee on Presidential Libraries. The meeting will be held to discuss the Presidential Library program and topics related to the public-private...

  13. 76 FR 41825 - NASA Advisory Council; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: (11-066)] NASA Advisory Council; Meeting... Space Administration announces a meeting of the NASA Advisory Council (NAC). The agenda topics for the....-12 p.m., Local Time. ADDRESSES: NASA Ames Conference Center (Building 3), Ballroom, 500 Severyns...

  14. 77 FR 43806 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-26

    ... COMMISSION ON CIVIL RIGHTS Sunshine Act Meeting AGENCY: United States Commission on Civil Rights. ACTION: Notice of meeting. DATE AND TIME: Friday, August 3, 2012; 2:00 p.m. EDT. PLACE: Via... prepared by Commission Kirsanow, for a briefing report; and (c) The topic of the civil rights of veterans...

  15. 77 FR 42760 - Notice of Public Meeting, Eastern Montana Resource Advisory Council Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... management in Montana. At these meetings, topics will include: Miles City and Billings Field Office manager.... Diane Friez, Eastern Montana -- Dakotas District Manager. [FR Doc. 2012-17712 Filed 7-19-12; 8:45 am...

  16. 77 FR 42507 - Notice of Public Meeting, Eastern Montana Resource Advisory Council Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-19

    ... management in Montana. At these meetings, topics will include: Miles City and Billings Field Office manager.... Diane Friez, Eastern Montana--Dakotas District Manager. [FR Doc. 2012-17567 Filed 7-18-12; 8:45 am...

  17. An Introduction to Topic Modeling as an Unsupervised Machine Learning Way to Organize Text Information

    ERIC Educational Resources Information Center

    Snyder, Robin M.

    2015-01-01

    The field of topic modeling has become increasingly important over the past few years. Topic modeling is an unsupervised machine learning way to organize text (or image or DNA, etc.) information such that related pieces of text can be identified. This paper/session will present/discuss the current state of topic modeling, why it is important, and…

  18. Topical therapies in the management of chronic rhinosinusitis: an evidence-based review with recommendations.

    PubMed

    Rudmik, Luke; Hoy, Monica; Schlosser, Rodney J; Harvey, Richard J; Welch, Kevin C; Lund, Valerie; Smith, Timothy L

    2013-04-01

    Topical therapies have become an integral component in the management plan for chronic rhinosinusitis (CRS). Several topical therapy strategies have been evaluated, but a formal comprehensive evaluation of the evidence has never been performed. The purpose of this article is to provide an evidence-based approach for the utilization of topical therapies in the management of CRS. A systematic review of the literature was performed and the guidelines for development of an evidence-based review with recommendations were followed. Study inclusion criteria were: adult population >18 years old; chronic rhinosinusitis (CRS) based on published diagnostic criteria; and clearly defined primary clinical end-point. We focused on reporting higher-quality studies (level 2b or higher), but reported on lower-level studies if the topic contained insufficient evidence. We excluded drug-eluting spacer and stent therapy from this review. This review identified and evaluated the literature on 5 topical therapy strategies for CRS: saline irrigation, topical steroid, topical antibiotic, topical antifungal, and topical alternatives (surfactant, manuka honey, and xylitol irrigations). Based on the available evidence, sinonasal saline irrigation and standard topical nasal steroid therapy are recommended in the topical treatment of CRS. Nonstandard (off-label) topical sinonasal steroid therapies can be an option for managing CRS. The evidence recommends against the use of topical antifungal therapy and topical antibiotic therapy delivered using nebulized and spray techniques in routine cases of CRS. There is insufficient clinical research to provide recommendations for alternative therapies or topical antibiotic therapy delivered using other delivery methods (eg, irrigations). © 2013 ARS-AAOA, LLC.

  19. Spaceship Nigeria: A Topic Study for Global Warming, Greenhouse Effect and Ozone Layer Depletion.

    ERIC Educational Resources Information Center

    Okebukola, Peter; Akpan, Ben B.

    1997-01-01

    Explains the concept of a topic study, how it meets the needs of teachers seeking to integrate their teaching, and how it is especially well suited for environmental education. Outlines curriculum for a topic study on the greenhouse effect and ozone layer depletion. (DDR)

  20. 2015 RAD Fall Partner Meeting

    EPA Pesticide Factsheets

    This meeting covered the following discussion topics: 2014 RAD partner achievements and trends, national and international efforts to address HFCs, enhancing RAD partner recognition, and communicating the benefits of RAD.

  1. TOWN HALL MEETING-SCCM 2009

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eggert, J.; Ryan, S. J.; Ramesh, K. T.

    2009-12-28

    The following article contains the summary of the discussion held at the Shock Compression of Condensed Matter Town Hall Meeting. This was held on Tuesday afternoon of the meeting and attracted 100+ attendees. This meeting, chaired by John Eggert, was planned to introduce challenges in selected topics relevant to shock wave science. The three subjects and speakers were: space research introduced by Shannon Ryan, nanotechnology presented by Kaliat T. Ramesh, and compression tools delivered by Dave Funk. After each presentation there were a number of questions.

  2. An analysis of the effectiveness of two topical anesthetics.

    PubMed Central

    Rosivack, R. G.; Koenigsberg, S. R.; Maxwell, K. C.

    1990-01-01

    This study compared the effectiveness of topical benzocaine 20%, lidocaine 5%, and a placebo in reducing the pain caused by needle insertion when the medicament was placed in the mucobuccal fold above the maxillary canine eminence. Both topical anesthetics and the placebo were randomly tested against each other bilaterally. For uniformity the agents were left in place for three minutes before needle insertion. A 27 gauge short needle mounted on an aspirating syringe was then inserted just past the bevel. Each subject rated the degree of pain on a visual analogue scale 100 mm in length. A pulse oximeter was used to record the heart rate. The results indicate that both topical anesthetics are significantly better than the placebo in reducing pain caused by needle insertion, although no statistically significant differences were found between the two topical anesthetics. Statistically significant differences in heart rate were seen, but these differences were not clinically significant. It is concluded that benzocaine 20% and lidocaine 5% significantly reduce the pain during needle insertion. PMID:2097909

  3. 78 FR 24433 - Notice of Public Meeting of the Central California Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-25

    ... meeting, agenda topics will include an update on Resource Management Plans and other resource management... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLCAC01000 L10100000.XZ0000 LXSIOVHD0000... Management, Interior. ACTION: Notice of Public Meeting. SUMMARY: In accordance with the Federal Land Policy...

  4. 78 FR 32244 - SFIREG Full Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ... Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group.... This notice announces the location and times for the meeting and sets forth the tentative agenda topics... http://www.epa.gov/dockets . II. Tentative Agenda Topics The following are tentative agenda topics for...

  5. "1999 Bioastronomy Meeting"

    NASA Technical Reports Server (NTRS)

    Meech, Karen J. (Editor); Owen, Tobias C.

    2000-01-01

    The 6th Bioastronomy Conference, Bioastronomy '99: A New Era in Bioastronomy, was held at the Hapuna Prince Beach hotel on the Big Island of Hawaii from August 2-6, 1999. The series of previous Bioastronomy meetings have played an important role in integrating the broader interests and techniques of both astronomy and biology to understand the origin and evolution of living systems in the universe, and to generating a context for exploration in our solar system and in extrasolar planetary systems. The scope of these interdisciplinary fields is captured in the topics discussed at the meeting: organic molecules in interstellar and interplanetary space; origin and evolution of planetary systems; comets, asteroids, and other small bodies and their role in the origin and evolution of life; Earth as a living planet; extreme environments on Earth; origin of life; transport of life between planets; evolution of life and intelligence; detection and characterization of extrasolar planets; search for extraterrestrial technology and life; future missions; and public acceptance and support of scientific studies of life in the universe. This paper gives an overview summary of the conference and briefly highlights some of the themes discussed at the meeting.

  6. Increased Topical Generic Prices by Manufacturers: An Isolated Trend or Worrisome Future?

    PubMed

    Bhatt, Mehul D; Bhatt, Birju D; Dorrian, James T; McLellan, Beth N

    2018-03-12

    There is limited data regarding generic medication prices. Recent studies have shown price changes at the retail level, but much is not known about the pharmaceutical supply chain or price changes at the manufacturer level. We sought to examine the extent of price changes for topical generic medications. A comprehensive review of average wholesale prices (AWP) and manufacturers of topical generics and available corresponding branded medications was conducted for 2005 and 2016. A total of 51 topical chemical entities were examined. Between 2005 and 2016, the AWP of topical generics increased by 273% and the AWP of topical branded increased by 379%. The topical generic with the most price change increased by 2529%. Eight of the top twenty topical generics with the highest increase in AWP also had an increase in the number of manufacturers. These findings are not generalizable to medications used in other areas of medicine CONCLUSIONS: Topical generic prices are rapidly increasing at the manufacturer level. Copyright © 2018. Published by Elsevier Inc.

  7. Serving At-Risk Youth. The Cutting Edge: New R&D Products. Special Topical Issue.

    ERIC Educational Resources Information Center

    Regional Laboratory for Educational Improvement of the Northeast & Islands, Andover, MA.

    This document is an annotated bibliography of research and development publications on topics concerning services to at-risk youth. The 30 publications, which have been produced by a variety of organizations, are grouped into these categories: (1) increasing academic success; (2) meeting diversity in today's students; (3) community partnerships;…

  8. 78 FR 2293 - NASA Advisory Council; Science Committee; Astrophysics Subcommittee; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-10

    ... Committee; Astrophysics Subcommittee; Meeting AGENCY: National Aeronautics and Space Administration. ACTION... amended, the National Aeronautics and Space Administration (NASA) announces a meeting of the Astrophysics... meeting includes the following topics: --Astrophysics Division Update --NASA Astrophysics Roadmapping It...

  9. 77 FR 26576 - Notice of Public Meeting of the Central California Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... this meeting, agenda topics will include an update on Resource Management Plans and other resource management issues. Additional ongoing business will be discussed by the council. All meetings are open to the... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLCAC01000 L10100000.XZ0000 LXSIOVHD0000...

  10. 75 FR 34765 - Advisory Committee on Water Information (ACWI); Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-18

    ... DEPARTMENT OF THE INTERIOR Advisory Committee on Water Information (ACWI); Meeting AGENCY: United... Committee on Water Information (ACWI). SUMMARY: Notice is hereby given of a meeting of the ACWI. This meeting is to discuss broad policy-related topics relating to national water initiatives, and the...

  11. HierarchicalTopics: visually exploring large text collections using topic hierarchies.

    PubMed

    Dou, Wenwen; Yu, Li; Wang, Xiaoyu; Ma, Zhiqiang; Ribarsky, William

    2013-12-01

    Analyzing large textual collections has become increasingly challenging given the size of the data available and the rate that more data is being generated. Topic-based text summarization methods coupled with interactive visualizations have presented promising approaches to address the challenge of analyzing large text corpora. As the text corpora and vocabulary grow larger, more topics need to be generated in order to capture the meaningful latent themes and nuances in the corpora. However, it is difficult for most of current topic-based visualizations to represent large number of topics without being cluttered or illegible. To facilitate the representation and navigation of a large number of topics, we propose a visual analytics system--HierarchicalTopic (HT). HT integrates a computational algorithm, Topic Rose Tree, with an interactive visual interface. The Topic Rose Tree constructs a topic hierarchy based on a list of topics. The interactive visual interface is designed to present the topic content as well as temporal evolution of topics in a hierarchical fashion. User interactions are provided for users to make changes to the topic hierarchy based on their mental model of the topic space. To qualitatively evaluate HT, we present a case study that showcases how HierarchicalTopics aid expert users in making sense of a large number of topics and discovering interesting patterns of topic groups. We have also conducted a user study to quantitatively evaluate the effect of hierarchical topic structure. The study results reveal that the HT leads to faster identification of large number of relevant topics. We have also solicited user feedback during the experiments and incorporated some suggestions into the current version of HierarchicalTopics.

  12. Identifying the Priority Topics for the Assessment of Competence in Care of the Elderly

    PubMed Central

    Frank, Chris C.; Allen, Tim; Lozanovska, Tatjana; Arcand, Marcel; Feldman, Sidney; Lam, Robert E.; Mehta, Pravinsagar G.; Mangal, Nadia Y.

    2018-01-01

    Background With Canada’s senior population increasing, there is greater demand for family physicians with enhanced skills in Care of the Elderly (COE). The College of Family Physicians Canada (CFPC) has introduced Certificates of Added Competence (CACs), one being in COE. Our objective is to summarize the process used to determine the Priority Topics for the assessment of competence in COE. Methods A modified Delphi technique was used, with online surveys and face-to-face meetings. The Working Group (WG) of six physicians acted as the nominal group, and a larger group of randomly selected practitioners from across Canada acted as the Validation Group (VG). The WG, and then the VG, completed electronic write-in surveys that asked them to identify the Priority Topics. Responses were compiled, coded, and tabulated to identify the topics and to calculate the frequencies of their selection. The WG used face-to-face meetings and iterative discussion to decide on the final topic names. Results The correlation between the initial Priority Topic list identified by the VG and that identified by the WG is 0.6793. The final list has 18 Priority Topics. Conclusion Defining the required competencies is a first step to establishing national standards in COE. PMID:29581816

  13. 78 FR 20356 - NASA Advisory Council; Science Committee; Astrophysics Subcommittee; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-04

    ... Committee; Astrophysics Subcommittee; Meeting AGENCY: National Aeronautics and Space Administration. ACTION... amended, the National Aeronautics and Space Administration (NASA) announces a meeting of the Astrophysics... password [email protected] The agenda for the meeting includes the following topics: --Astrophysics Division...

  14. 76 FR 66998 - NASA Advisory Council; Science Committee; Astrophysics Subcommittee; Meeting.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... Committee; Astrophysics Subcommittee; Meeting. AGENCY: National Aeronautics and Space Administration. ACTION... amended, the National Aeronautics and Space Administration (NASA) announces a meeting of the Astrophysics... open to the public. The agenda for the meeting includes the following topic: --Astrophysics Division...

  15. Coordinating Council. Eighth Meeting: Using the Internet

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This NASA Scientific and Technical Information Program Coordinating Council meeting theme was entitled 'Using Internet'. Individual topics included STI LAN migration, NSF and NREN (National Science Foundation and the National Research and Education Network), and the New NASA Headquarters LAN. Discussions are recorded for each topic and visuals are provided for STI LAN migration and NSI - NASA Science Internet.

  16. Designing Successful Professional Meetings and Conferences in Education: Planning, Implementation, and Evaluation.

    ERIC Educational Resources Information Center

    Mundry, Susan; Britton, Edward; Raizen, Senta; Loucks-Horsley, Susan

    This book outlines the principles of planning, implementing, and evaluating successful professional meetings and conferences in education. The following are among the topics discussed: (1) the knowledge base of effective meetings and conferences (nine principles held by effective meeting designers; characteristics of effective meetings and…

  17. 75 FR 842 - Notice of Central Idaho Resource Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-06

    ... Central Idaho Resource Advisory Committee Meeting AGENCY: Forest Service, USDA. ACTION: Notice of Meeting... National Forest's Central Idaho Resource Advisory Committee will conduct a business meeting which is open.... South Zone Office, Highway 93, Challis, Idaho. SUPPLEMENTARY INFORMATION: Agenda topics will include...

  18. 76 FR 43705 - Notice of Public Meeting, Dakotas Resource Advisory Council Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... in the Dakotas. At these meetings, topics will include: North Dakota and South Dakota Field Office manager updates, subcommittee briefings, work sessions and other issues that the council may raise. All.... M. Elaine Raper, Manager, Eastern Montana, Dakotas District . [FR Doc. 2011-18376 Filed 7-20-11; 8...

  19. Hybrid Fiber/Copper LAN Meets School's 25-Year Networking Requirements.

    ERIC Educational Resources Information Center

    Petruso, Sam; Humes, Vince

    1994-01-01

    Describes an innovative new curriculum being implemented at Walnut Creek Middle School (Pennsylvania) and an advanced networked computer environment that supports it now and will also meet future needs. Topics addressed include physical facilities; networking goals, both short-term and long-term; fiber-optic cable versus copper; and future…

  20. Landsat science team meeting: Summer 2015

    USGS Publications Warehouse

    Schroeder, Todd; Loveland, Thomas; Wulder, Michael A.; Irons, James R.

    2015-01-01

    With over 60 participants in attendance, this was the largest LST meeting ever held. Meeting topics on the first day included Sustainable Land Imaging and Landsat 9 development, Landsat 7 and 8 operations and data archiving, the Landsat 8 Thermal Infrared Sensor (TIRS) stray-light issue, and the successful Sentinel-2 launch. In addition, on days two and three the LST members presented updates on their Landsat science and applications research. All presentations are available at landsat.usgs.gov/science_LST_Team_ Meetings.php.

  1. Major research topics in combustion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hussaini, M.Y.; Kumar, A.; Voigt, R.G.

    1992-01-01

    The Institute for Computer Applications in Science and Engineering (ICASE) and NASA Langley Research Center (LaRC) hosted a workshop on October 2--4, 1989 to discuss some combustion problems of technological interest to LaRC and to foster interaction with the academic community in these research areas. The topics chosen for this purpose were flame structure, flame holding/extinction, chemical kinetics, turbulence-kinetics interaction, transition to detonation, and reacting free shear layers. This document contains the papers and edited versions of general discussions on these topics. The lead paper set the stage for the meeting by discussing the status and issues of supersonic combustionmore » relevant to the scramjet engine. Experts were then called upon to review the current knowledge in the aforementioned areas, to focus on how this knowledge can be extended and applied to high-speed combustion, and to suggest future directions of research in these areas.« less

  2. 75 FR 15743 - NASA Advisory Council; Exploration Committee; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-034)] NASA Advisory Council; Exploration... Aeronautics and Space Administration announces a meeting of the Exploration Committee of the NASA Advisory...-358-1715; [email protected]nasa.gov . SUPPLEMENTARY INFORMATION: The agenda topics for the meeting will...

  3. 77 FR 61586 - Notice of Attendance at NYISO Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... (Management, Business Issues, and Operating) meet on a variety of topics; they convene and dissolve on an as... postings on the NYISO Web site. NYISO Business Issues Committee October 17, 2012 (Rensselaer, NY). November... (Rensselaer, NY). September 18, 2013 (Rensselaer, NY). NYISO Management Committee October 31, 2012 (Rensselaer...

  4. 76 FR 14389 - Notice of Attendance at NYISO Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... (Management, Business Issues, and Operating) meet on a variety of topics; they convene and dissolve on an as... postings on the NYISO Web site. NYISO Business Issues Committee March 9, 2011 (Rensselaer, NY) April 13... (Rensselaer, NY) November 9, 2011 (Rensselaer, NY) December 14, 2011 (Rensselaer, NY) NYISO Management...

  5. My Most Memorial Meeting - The June, 1997, San Diego Meeting

    NASA Astrophysics Data System (ADS)

    Philip, A. G. Davis

    1999-05-01

    At the June, 1997 AAS meeting in San Diego I arranged a topical session on the Shapley Visiting Lectureships Program. There were poster papers and speakers from the early days of the program, going back to the Visiting Lectureships Program of the AAS. Then the three past directors and the present director described their activities in running the program from 1979 to 1997. We had other speakers who described their many visits to institutions over the years and representatives from two institutions which had received many visits. This session provided much interesting information about the Shapley Program and its history. At the end of the program several people pledged, and then gave, a substantial sum to the Shapley Endowment Fund. Because of all these events and happenings, the San Diego Meeting was a highlight meeting for me. A second meeting with significance to the Shapley Program was the June, 1996 meeting in Madison, Wisconsin. At this meeting certificates were awarded to 31 lecturers who had made 15 or more Shapley visits and 18 lecturers who had made 25 or more visits. A dinner was held at which those lecturers in these two groups who were present at the meeting were personally awarded their certificates. The remaining certificates were mailed after the meeting. The success of the Shapley Program is directly related to the devotion of its group of lecturers who spend considerable time and effort in making the two day visits to host institutions.

  6. 75 FR 9598 - Tribal Pesticide Program Council; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ... tentative agenda topics. DATES: The meeting will be held on Wednesday, March 17, 2010, from 9 a.m. to 5 p.m... holidays. The Docket Facility telephone number is (703) 305-5805. II. Tentative Agenda Topics 1. Worker...

  7. Landsat Science Team meeting: Winter 2015

    USGS Publications Warehouse

    Schroeder, Todd A.; Loveland, Thomas; Wulder, Michael A.; Irons, James R.

    2015-01-01

    The summer meeting of the joint U.S. Geological Survey (USGS)–NASA Landsat Science Team (LST) was held at the USGS’s Earth Resources Observation and Science (EROS) Center July 7-9, 2015, in Sioux Falls, SD. The LST co-chairs, Tom Loveland [EROS—Senior Scientist] and Jim Irons [NASA’s Goddard Space Flight Center (GSFC)—Landsat 8 Project Scientist], opened the three-day meeting on an upbeat note following the recent successful launch of the European Space Agency’s Sentinel-2 mission on June 23, 2015 (see image on page 14), and the news that work on Landsat 9 has begun, with a projected launch date of 2023.With over 60 participants in attendance, this was the largest LST meeting ever held. Meeting topics on the first day included Sustainable Land Imaging and Landsat 9 development, Landsat 7 and 8 operations and data archiving, the Landsat 8 Thermal Infrared Sensor (TIRS) stray-light issue, and the successful Sentinel-2 launch. In addition, on days two and three the LST members presented updates on their Landsat science and applications research. All presentations are available at landsat.usgs.gov/science_LST_Team_ Meetings.php.

  8. 76 FR 78691 - Notice of Public Meeting; Wyoming Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... agenda topics include an overview of the BLM's planning process, the Casper Resource Management Plan, a... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLWY910000 L16100000 XX0000] Notice of Public Meeting; Wyoming Resource Advisory Council AGENCY: Bureau of Land Management, Interior. ACTION...

  9. 76 FR 59172 - NASA Advisory Council; Science Committee; Astrophysics Subcommittee; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... Committee; Astrophysics Subcommittee; Meeting AGENCY: National Aeronautics and Space Administration. ACTION... amended, the National Aeronautics and Space Administration (NASA) announces a meeting of the Astrophysics... topics: --Astrophysics Division Update. --James Webb Space Telescope Follow-Up. --Wide Field Infrared...

  10. Selected Research and Development Topics on Aerospace Communications at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Miranda, Felix A.; Romanofsky, Robert R.; Nessel, James A.

    2014-01-01

    This presentation discusses some of the efforts on communications RD that have been performed or are currently underway at NASA Glenn Research Center. The primary purpose of this presentation is to outline some RD topics to serve as talking points for a Technical Interchange Meeting with the Ohio State University. The meeting is scheduled to take place at The ElectroScience Laboratory of the Ohio State University on February 24, 2014.

  11. Global issues from an African point of view. 7th International Women and Health Meeting in Uganda.

    PubMed

    Shallat, L

    1993-01-01

    The seventh International Women and Health Meeting (IWHM) was held in Kampala, Uganda, during September 12-17, 1993. The purpose of the meeting was to devise strategies to confront such issues as the impact of economic policies on women's health, the implementation of reproductive rights, population control and policies, contraceptive technologies, AIDS, and sexual abuse and violence. In addition to these topics, discussion centered on interaction with the upcoming 1994 International Conference on Population and Development. Some participants were frustrated, however, by the procedural problems that prevented creation of a cohesive position paper and left important strategic questions unanswered. Women from Latin America and the Caribbean were kept from full participation by the lack of a Spanish translator but nevertheless held an information session on regional developments in abortion reform and population policy. These women were also successful in their bid to host the eighth IWHM in Brazil in 1996.

  12. Topical Antimicrobials for Burn Infections – An Update

    PubMed Central

    Sevgi, Mert; Toklu, Ani; Vecchio, Daniela; Hamblin, Michael R

    2014-01-01

    The relentless rise in antibiotic resistance among pathogenic bacteria and fungi, coupled with the high susceptibility of burn wounds to infection, and the difficulty of systemically administered antibiotics to reach damaged tissue, taken together have made the development of novel topical antimicrobials for burn infections a fertile area of innovation for researchers and companies. We previously covered the existing patent literature in this area in 2010, but the notable progress made since then, has highlighted the need for an update to bring the reader up to date on recent developments. New patents in the areas of topically applied antibiotics and agents that can potentiate the action of existing antibiotics may extend their useful lifetime. Developments have also been made in biofilm-disrupting agents. Antimicrobial peptides are nature’s way for many life forms to defend themselves against attack by pathogens. Silver has long been known to be a highly active antimicrobial but new inorganic metal derivatives based on bismuth, copper and gallium have emerged. Halogens such as chlorine and iodine can be delivered by novel technologies. A variety of topically applied antimicrobials include chitosan preparations, usnic acid, ceragenins and XF porphyrins. Natural product derived antimicrobials such as tannins and essential oils have also been studied. Novel techniques to deliver reactive oxygen species and nitric oxide in situ have been developed. Light-mediated techniques include photodynamic therapy, ultraviolet irradiation, blue light, low-level laser therapy and titania photocatalysis. Passive immunotherapy employs antibodies against pathogens and their virulence factors. Finally an interesting new area uses therapeutic microorganisms such as phages, probiotic bacteria and protozoa to combat infections. PMID:24215506

  13. Topical Steroid Damaged/Dependent Face (TSDF): An Entity of Cutaneous Pharmacodependence

    PubMed Central

    Lahiri, Koushik; Coondoo, Arijit

    2016-01-01

    Topical Steroid Damaged/Dependent face (TSDF) is a phenomenon which has been described very recently (2008). It is characterized by a plethora of symptoms caused by an usually unsupervised misuse/abuse/overuse of topical corticosteroid of any potency on the face over an unspecified and/or prolonged period of time. This misuse and damage have a serious effect on the quality of life of the patients in general and the skin of the face in particular. Management is difficult and necessitates psychological counseling as well as physical soothing of the sensitive skin. PMID:27293246

  14. 77 FR 29637 - SFIREG Full Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group.... This notice announces the location and times for the meeting and sets forth the tentative agenda topics... holidays. The Docket Facility telephone number is (703) 305-5805. II. Tentative Agenda Topics 1. Office of...

  15. 78 FR 14537 - SFIREG Full Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ... Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group... and sets forth the tentative agenda topics. DATES: The meeting will be held on Monday, April 22, 2013... information about the docket available at http://www.epa.gov/dockets . II. Tentative Agenda Topics 1. Bee...

  16. 76 FR 30343 - SFIREG Full Working Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group.... This notice announces the location and times for the meeting and sets forth the tentative agenda topics.... II. Tentative Agenda Topics 1. Progress on Issue Papers: [[Page 30344

  17. Reflective topical autobiography: an under utilised interpretive research method in nursing.

    PubMed

    Johnstone, M J

    1999-01-01

    Reflective topical autobiography (an autobiographical method) belongs to the genre of testimonial research and is located within the postpositivist interpretive research paradigm. Despite the (reflective) topical autobiographical method enjoying a 'rebirth' in recent years and being utilised by a range of researchers in the human and literary disciplines, it remains largely unknown and under utilised in nursing research domains. In this article it is proposed that reflective topical autobiography is an important research method in its own right, and one which promises to make a substantive contribution to the overall project of advancing nursing inquiry and knowledge. This is particularly so where nursing research shares in the affirming projects of interpretive research generally and the relatively new sociology of the emotions in particular apropos: (i) increasing understanding of subjectivity and making subjective experiences more visible and intelligible, (ii) the search for meaning and increasing understanding of the commonality of existential human experience, and (iii) decentring the detached observer and his/her privileging the objectivist illusion in the hierarchy of research discourses, paving the way for the admission of multiple realities and interpretations of lived experience. In this article, a coherent reflective topical autobiographical research method is advanced for use in nursing education and research contexts.

  18. Core continuing professional development (CPD) topics for the European dentist.

    PubMed

    Bailey, S; Bullock, A; Cowpe, J; Barnes, E; Thomas, H; Thomas, R; Kavadella, A; Kossioni, A; Karaharju-Suvanto, T; Suomalainen, K; Kersten, H; Povel, E; Giles, M; Walmsley, A D; Soboleva, U; Liepa, A; Akota, I

    2013-05-01

    In the context of free movement, EU-citizens need assurance that dental practitioners providing their care have a degree/license to practice that meets EU-standards and that they maintain their knowledge and skills through ongoing education. One aim of the 'DentCPD' project (HYPERLINK 'http://www.dentcpd.org' www.dentcpd.org) was to identify and agree essential CPD requirements for EU dentists. This paper reports the consensus process and outcomes. Agreement on core components of CPD was achieved through a three stage process: an online survey of dental educators' (n = 143) views on compulsory topics; a paper-based questionnaire to practitioners (n = 411); leading to a proposal discussed at the Association for Dental Education (ADEE) 2011 Lifelong Learning special interest group (SIG). From the online survey and practitioner questionnaire, high levels of agreement were achieved for medical emergencies (89%), infection control (79%) and the medically compromised patient (71%). The SIG (34 attendees from 16 countries) concluded that these three CPD topics plus radiation protection should be core-compulsory and three CPD topics should be core-recommended (health and safety, pain management, and safeguarding children & vulnerable adults). They also agreed that the teaching of all topics should be underpinned by evidence-based dentistry. Building four core topics into CPD requirements and making quality-approved education and training available will ensure that all dentists have up-to-date knowledge and skills in topic areas of direct relevance to patient safety. In turn, this will contribute to patients having access to comparably high standards of oral health care across Europe. © 2013 John Wiley & Sons A/S.

  19. TT2014 meeting report on the 12th Transgenic Technology meeting in Edinburgh: new era of transgenic technologies with programmable nucleases in the foreground.

    PubMed

    Beck, Inken M; Sedlacek, Radislav

    2015-02-01

    The 12th Transgenic Technology meeting was held in Edinburgh on 6th-8th October 2014 and interest to participate in the meeting overcame all expectations. The TT2014 was the largest meeting ever with more than 540 scientists, technicians, and students from all over the world. The meeting had an excellent scientific program that brought information on the latest ground-breaking technologies for gene targeting and genome editing using programmable nucleases into the foreground. These presentations were well balanced with several highlights over viewing topics in embryonic stem cell research, embryogenesis, disease models, and animals in agriculture. Ample space was reserved also for short talks presenting technical development and for highlighting posters contributions. A highlight of the meeting was the award of the 10th International Society of Transgenic Technologies Prize to Janet Rossant for her outstanding contributions in the field of mouse embryogenesis.

  20. Proceedings of the State Directors of Correctional Education Annual Meeting (4th, Atlanta, Georgia, July 14, 1985).

    ERIC Educational Resources Information Center

    Office of Vocational and Adult Education (ED), Washington, DC.

    This document contains the proceedings of an annual meeting of state directors of correctional education on the topic of "special needs of the female offender." Dianne Carter of the U.S. Department of Education's Correction Education Program opened the meeting with welcoming comments and reported on many activities of the corrections education…

  1. 77 FR 69837 - SFIREG Full Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group... topics. DATES: The meeting will be held on Monday, December 10, 2012, from 8:30 a.m. to 5 p.m. and...://www.epa.gov/dockets . II. Tentative Agenda Topics 1. Responses to SFIREG Pyrethroid labeling issue...

  2. Highlights of 2012 Fall Meeting

    NASA Astrophysics Data System (ADS)

    Finn, Carol

    2013-01-01

    This past December the streets of San Francisco, Calif., surrounding the Moscone Center were awash with a sea of Earth and space scientists attending the 45th consecutive AGU Fall Meeting, eager to share and expand their knowledge "for the benefit of humanity." As it has for many years, attendance at AGU's Fall Meeting—the largest gathering of Earth and space scientists in the world—continued to increase, this year passing the 24,000 mark. Attendees at the meeting, which took place on 3-7 December 2012, hailed from 97 countries; nearly 7000 of them were students. News from the Fall Meeting was carried in newspapers and on Web sites around the world, and the social media sphere lit up with talk of AGU and the Fall Meeting. It's even reported that for a short time we were a trending topic on Twitter.

  3. 78 FR 23223 - Marine Fisheries Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ... agenda is subject to change. The meeting is convened to hear presentations and discuss policies and guidance on the following topics: Fisheries certification and sustainability, Endangered Species Act and...

  4. On the Presentation of Pre-Calculus and Calculus Topics: An Alternate View

    ERIC Educational Resources Information Center

    Davydov, Aleksandr; Sturm-Beiss, Rachel

    2008-01-01

    The orders of presentation of pre-calculus and calculus topics, and the notation used, deserve careful study as they affect clarity and ultimately students' level of understanding. We introduce an alternate approach to some of the topics included in this sequence. The suggested alternative is based on years of teaching in colleges within and…

  5. 76 FR 55380 - SFIREG EQI Working Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    ... Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group... and sets forth the tentative agenda topics. DATES: The meeting will be held on Monday, October 17.... II. Tentative Agenda Topics 1. Endangered Species Act--``the services'' on their process and...

  6. 76 FR 21892 - SFIREG POM Working Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-19

    ... Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group... and sets forth the tentative agenda topics. DATES: The meeting will be held on Monday, May 16, 2011... Topics 1. Implementing and communicating major pesticide regulatory changes--Panel discussion. 2. SFIREG...

  7. 75 FR 8788 - Railroad Safety Advisory Committee; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... rescheduled from the weather- postponed February 11, 2010, meeting (75 FR 3959). The RSAC meeting topics will... Control, Passenger Hours of Service, and Railroad Bridge Safety Management. A new task regarding minimum... agreement to consider one or more items of business by mail ballot, including proposed requirements for...

  8. 75 FR 56994 - Mid-Atlantic Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National... 21-22, 2010 SSC meeting included the following topics: (1) new SSC member orientation, (2) review..., National Marine Fisheries Service. [FR Doc. 2010-23204 Filed 9-16-10; 8:45 am] BILLING CODE 3510-22-S ...

  9. 77 FR 56840 - Meeting of the Environmental Financial Advisory Board-Public Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9727-8] Meeting of the Environmental Financial Advisory Board... meeting. SUMMARY: The United States Environmental Protection Agency's (EPA) Environmental Financial... expected on the following topics: Clean air technology; tribal environmental programs; transit-oriented...

  10. Satellite DNA: An Evolving Topic

    PubMed Central

    Garrido-Ramos, Manuel A.

    2017-01-01

    Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a lot of literature has extensively covered various topics related to the structure, organization, function, and evolution of such sequences. Today, with the advent of genomic tools, the study of satellite DNA has regained a great interest. Thus, Next-Generation Sequencing (NGS), together with high-throughput in silico analysis of the information contained in NGS reads, has revolutionized the analysis of the repetitive fraction of the eukaryotic genomes. The whole of the historical and current approaches to the topic gives us a broad view of the function and evolution of satellite DNA and its role in chromosomal evolution. Currently, we have extensive information on the molecular, chromosomal, biological, and population factors that affect the evolutionary fate of satellite DNA, knowledge that gives rise to a series of hypotheses that get on well with each other about the origin, spreading, and evolution of satellite DNA. In this paper, I review these hypotheses from a methodological, conceptual, and historical perspective and frame them in the context of chromosomal organization and evolution. PMID:28926993

  11. 76 FR 51053 - Meeting of the California Desert District Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-17

    ..., from 8 a.m. to 5 p.m. at the Hampton Inn & Suites, 2710 Lenwood Rd., Barstow, CA 92311. There will be a.../info/rac/dac.html , when finalized. Agenda topics for the Saturday meeting will include recreation fees... meeting is tentatively scheduled from 8 a.m. to 5 p.m., the meeting could conclude prior to 5 p.m. should...

  12. 1995 AAAS annual meeting and science innovation exposition: Unity in diversity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Strauss, M.S.; Heasley, C.

    1995-12-31

    Abstracts are presented from the 161st National Meeting of the American Association for the advancement of Science. Topics include environmental technologies, genetics, physical science research, information management, nuclear weapon issues, and education. Individual topics have been processed separately for the United States Department of Energy databases.

  13. 78 FR 33851 - Lung Cancer Patient-Focused Drug Development; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ... categories: therapies to reduce or control the spread of disease (including surgery, radiation therapy... meeting are provided in the paragraphs that follow. For each of these topics, a brief initial patient... the public docket (see ADDRESSES). Topic 1: Disease Symptoms and Daily Impacts That Matter Most to...

  14. Expert Meeting Report: Energy Savings You Can Bank On

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beman, M.; Springer, J.; Smith, P.

    In October 2011, ARBI organized and conducted an Experts' Meeting on the topic of performance guarantees and financing vehicles for Energy Efficiency Upgrades. The meeting brought together technical, policy, and financial experts, including researchers, experienced installation contractors, and innovative energy business leaders, in order to discuss the opportunities and challenges for the energy efficiency upgrade industry to increase market uptake of Home Energy Upgrades (HEUs) through innovative offerings, such as performance guarantees. The meeting had several primary goals. First, it sought to understand how other industries have developed successful models for financing renewable energy installations while providing performance guarantees. Thismore » has been most recently demonstrated by the solar leasing industry. Second, the meeting explored the applicability of such business models to the energy efficiency upgrade industry. Third, the meeting sought to identify technical impediments to performance guarantees for energy efficiency retrofits. Fourth, the meeting sought to provide a common framework for these goals within the context of current financing mechanisms for energy efficiency upgrades.« less

  15. 76 FR 61074 - Reports and Updates on Arctic Research Programs and Projects; Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ... UNITED STATES ARCTIC RESEARCH COMMISSION Reports and Updates on Arctic Research Programs and Projects; Meetings Notice is hereby given that the US Arctic Research Commission will hold its 96th meeting... about topics of interest related to research activities in the Arctic. 96th Meeting Schedule: Wed., Oct...

  16. 78 FR 69665 - SFIREG Full Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-20

    ...The Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group (SFIREG), Full Committee will hold a 2-day meeting, beginning on December 9, 2013 and ending December 10, 2013. This notice announces the location and times for the meeting and sets forth the tentative agenda topics.

  17. 77 FR 65856 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-31

    ... COMMISSION ON CIVIL RIGHTS Sunshine Act Meeting AGENCY: United States Commission on Civil Rights.... This briefing is open to the public. Topic: The Federal Civil Rights Engagement With Arab and Muslim... Civil Rights Organizations Panel-- Speakers' Remarks and Questions From Commissioners III. Panel II...

  18. Topical treatment of psoriasis.

    PubMed

    Laws, Philip M; Young, Helen S

    2010-08-01

    The majority of patients with psoriasis can be safely and effectively treated with topical therapy alone, either under the supervision of a family physician or dermatologist. For those requiring systemic agents, topical therapies can provide additional benefit. Optimal use of topical therapy requires an awareness of the range and efficacy of all products. The review covers the efficacy and role of topical therapies including emollients, corticosteroids, vitamin D analogs, calcineurin inhibitors, dithranol, coal tar, retinoids, keratolyics and combination therapy. The report was prepared following a PubMed and Embase literature search up to April 2010. The paper provides a broad review of the relevant topical therapeutic options available in routine clinical practice for the management of psoriasis and a recommendation for selection of treatment. Topical therapies used appropriately provide a safe and effective option for the management of psoriasis. An awareness of the available products and their efficacy is key to treatment selection and patient satisfaction.

  19. 1999 Bioastronomy Meeting

    NASA Technical Reports Server (NTRS)

    Meech, Karen J.; Caroff, Lawrence J. (Technical Monitor)

    2001-01-01

    The 6th Bioastronomy Conference, Bioastronomy '99: A New Era in Bioastronomy, was held at the Hapuna Prince Beach hotel on the Big Island of Hawaii from August 2-6, 1999. The series of previous Bioastronomy meetings have played an important role in integrating the broader interests and techniques of both astronomy and biology to understand the origin and evolution of living systems in the universe, and to generating a context for exploration in our solar system and in extrasolar planetary systems. The scope of these interdisciplinary fields is captured in the topics discussed at the meeting: organic molecules in interstellar and interplanetary space; origin and evolution of planetary systems; comets, asteroids, and other small bodies and their role in the origin and evolution of life; Earth as a living planet; extreme environments on Earth; origin of life; transport of life between planets; evolution of life and intelligence; detection and characterization of extrasolar planets; search for extraterrestrial technology and life; future missions; and public acceptance and support of scientific studies of life in the universe.

  20. Topical oxygen as an adjunct to wound healing: a clinical case series.

    PubMed

    Kalliainen, Loree K.; Gordillo, Gayle M.; Schlanger, Richard; Sen, Chandan K.

    2003-01-01

    BACKGROUND: Disrupted vasculature and high energy-demand to support processing and regeneration of wounded tissue are typical characteristics of a wound site. Oxygen delivery is a critical element for the healing of wounds. Clinical experience with adjunctive hyperbaric oxygen therapy in the treatment of chronic wounds have shown that wound hyperoxia increases wound granulation tissue formation and accelerates wound contraction and secondary closure. Nevertheless, the physiologic basis for this modality remains largely unknown. Also, systemic hyperbaric oxygen therapy is associated with risks related to oxygen toxicity. Topical oxygen therapy represents a less explored modality in wound care. The advantages of topical oxygen therapy include low cost, lack of systemic oxygen toxicity, and the ability to receive treatment at home, making the benefits of oxygen therapy available to a much larger population of patients. MATERIALS AND METHODS: Over 9 months, seven surgeons treated 58 wounds in 32 patients with topical oxygen with follow-up ranging from 1 to 8 months. The data presented herein is a retrospective analysis of the results we have achieved using topical oxygen on complex wounds. RESULTS: Thirty-eight wounds in 15 patients healed while on topical oxygen. An additional five wounds in five patients had preoperative oxygen therapy; all wounds initially healed postoperatively. In two patients, wounds recurred post-healing. In ten wounds, topical oxygen had no effect; and two of those patients went on to require limb amputation. There were no complications attributable to topical oxygen. Three patients died during therapy and one died in the first postoperative month from underlying medical problems. Two patients were lost to follow-up. CONCLUSIONS: In this case series, topical oxygen had no detrimental effects on wounds and showed beneficial indications in promoting wound healing.

  1. How to hold an effective meeting.

    PubMed

    Koshy, Kiron; Liu, Alison; Whitehurst, Katharine; Gundogan, Buket; Al Omran, Yasser

    2017-06-01

    Meetings are a common occurrence in academic and medical life. However, most of these meetings will be under-productive and inefficient uses of time. In this article, we provide valuable tips on how best to plan a meeting and get the most out of the people in attendance. This includes how to assess whether a meeting is necessary and what form this meeting should take. In addition to this, guidance is divided into before, during, and after the meeting. This guide will provide structure to your meetings and improve the output you and your team gain from them.

  2. 78 FR 67436 - Defense Trade Advisory Group; Notice of Open Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ... DEPARTMENT OF STATE [Public Notice 8515] Defense Trade Advisory Group; Notice of Open Meeting AGENCY: Department of State. ACTION: Notice of meeting. SUMMARY: The Defense Trade Advisory Group (DTAG.... Specific agenda topics will be posted on the Directorate of Defense Trade Controls Web site, at www.pmddtc...

  3. 2004 Environmental Mutagen Society Annual Meeting - Genes, Mutations and Disease: The Environmental Connection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Samson, Leona D.

    2004-08-23

    The Meeting consisted of 9 Symposia, 4 Keynote Lectures, 3 Platform Sessions and 4 Poster Sessions. In addition there were Breakfast Meetings for Special Interest Groups designed to inform attendees about the latest advances in environmental mutagenesis research. Several of the topics to be covered at this broad meeting will be of interest to the Department of Energy, Office of Science. The relevance of this meeting to the DOE derives from the fact that low dose radiation may represent one of the most significant sources of human mutations that are attributable to the environment. The EMS membership, and those whomore » attended the EMS Annual Meeting were interested in both chemical and radiation induced biological effects, such as cell death, mutation, teratogenesis, carcinogenesis and aging. These topics thate were presented at the 2004 EMS Annual meeting that were of clear interest to DOE include: human variation in cancer susceptibility, unusual mechanisms of mutation, germ and stem cell mutagenesis, recombination and the maintenance of genomic stability, multiple roles for DNA mismatch repair, DNA helicases, mutation, cancer and aging, Genome-wide transcriptional responses to environmental change, Telomeres and genomic stability: when ends don?t meet, systems biology approach to cell phenotypic decision processes, and the surprising biology of short RNAs. Poster and platform sessions addressed topics related to environmental mutagen exposure, DNA repair, mechanisms of mutagenesis, epidemiology, genomic and proteomics and bioinformatics. These sessions were designed to give student, postdocs and more junior scientists a chance to present their work.« less

  4. Relative efficacy of topical non-steroidal anti-inflammatory drugs and topical capsaicin in osteoarthritis: protocol for an individual patient data meta-analysis.

    PubMed

    Persson, Monica S M; Fu, Yu; Bhattacharya, Archan; Goh, Siew-Li; van Middelkoop, Marienke; Bierma-Zeinstra, Sita M A; Walsh, David; Doherty, Michael; Zhang, Weiya

    2016-09-29

    Pain is the most troubling issue to patients with osteoarthritis (OA), yet current pharmacological treatments offer only small-to-moderate pain reduction. Current guidelines therefore emphasise the need to identify predictors of treatment response. In line with these recommendations, an individual patient data (IPD) meta-analysis will be conducted. The study aims to investigate the relative treatment effects of topical non-steroidal anti-inflammatory drugs (NSAIDs) and topical capsaicin in OA and to identify patient-level predictors of treatment response. IPD will be collected from randomised controlled trials (RCTs) of topical NSAIDs and capsaicin in OA. Multilevel regression modelling will be conducted to determine predictors for the specific and the overall treatment effect. Through the identification of treatment responders, this IPD meta-analysis may improve the current understanding of the pain mechanisms in OA and guide clinical decision-making. Identifying and prescribing the treatment most likely to be beneficial for an individual with OA will improve the efficiency of patient management. CRD42016035254.

  5. AAPG-SEPM-SEG Pacific section meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1985-04-01

    The Pacific Section Meeting of the American Association of Petroleum Geologists is presented. Although topics varied, the bulk of the papers dealt with the geology and petroleum deposits of the Alaskan North Slope. Of the papers presented, 108 were indexed for the US Department of Energy's Data Base.

  6. EDITORIAL: The 24th Nordic Semiconductor Meeting The 24th Nordic Semiconductor Meeting

    NASA Astrophysics Data System (ADS)

    Páll Gunnlaugsson, Haraldur; Nylandsted Larsen, Arne; Uhrenfeldt, Christian

    2012-03-01

    A Nordic Semiconductor Meeting is held every other year with the venue rotating amongst the Nordic countries of Denmark, Finland, Iceland, Norway and Sweden. The focus of these meetings remains 'original research and science being carried out on semiconductor materials, devices and systems'. Reports on industrial activity have usually featured. The topics have ranged from fundamental research on point defects in a semiconductor to system architecture of semiconductor electronic devices. Proceedings from these events are regularly published as a Topical Issue of Physica Scripta. All of the papers in this Topical Issue have undergone critical peer review and we wish to thank the reviewers and the authors for their cooperation, which has been instrumental in meeting the high scientific standards and quality of the series. This 24th meeting of the Nordic Semiconductor community, NSM 2011, was held at Fuglsøcentret, close to Aarhus, Denmark, 19-22 June 2011. Support was provided by the Carlsberg Foundation, Danfysik and the semiconductor group at Aarhus University. Over 30 participants presented a broad range of topics covering semiconductor materials and devices as well as related material science interests. The conference provided a forum for Nordic and international scientists to present and discuss new results and ideas concerning the fundamentals and applications of semiconductor materials. The aim of the meeting was to advance the progress of Nordic science and thus aid in future worldwide technological advances concerning technology, education, energy and the environment. The 25th Nordic Semiconductor Meeting will be organized in June 2013 in Finland, chaired by Dr Filip Tuomisto, Aalto University. A Nordic Summer School on Semiconductor Science will be organized in connection with the conference (just before), chaired by Dr Jonatan Slotte, Aalto University. Information on these events can be found at physics.aalto.fi/nsm2013. List of participants Søren Vejling

  7. The 14th European Immunology Meeting--EFIS 2000. 23-27 September 2000, Poznañ, Poland.

    PubMed

    Wysocki, P J; Nawrocki, S; Mackiewicz, A

    2001-01-01

    The 14th European Immunology Meeting--EFIS 2000, held in Poznan, Poland on 23-27 September 2000, was the last major meeting of European immunologists in the second millennium. This conference was intended to summarise past achievements and to present future prospects in immunology. The philosophy of the scientific program was to fuse fundamental and clinical immunology and give a chance for basic scientists and clinicians to discuss mutual topics in a general view. There were eight state-of-art lectures, 12 'meet an expert' sessions, 20 plenary sessions and 46 workshops. More than 900 works were presented. Significant interest was focused on several aspects of cancer immunology and immunotherapy. EFIS 2000 was accompanied by six pre-congress satellite symposia held in various Polish cities. The topics were, 'Heat shock proteins: immune, stress response and apoptosis' (Gdansk), 'Infectious immunity and vaccines' (Kazimierz Dolny), 'Mononuclear phagocytes in basic and clinical immunology' (Cracow), 'Immunology of reproduction' (Poznan), 'Primary immunodeficiencies' (Warsaw) and 'Glycoimmunology' (Wroclaw).

  8. 76 FR 66248 - Negotiated Rulemaking Committee, Negotiator Nominations and Schedule of Committee Meetings...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-26

    ... by the topics proposed for negotiation. We request nominations for individual negotiators who... meetings are set out in the Schedule for Negotiations section under SUPPLEMENTARY INFORMATION, below... represent the interests significantly affected by the topics proposed for negotiations. In so doing, we will...

  9. Web image retrieval using an effective topic and content-based technique

    NASA Astrophysics Data System (ADS)

    Lee, Ching-Cheng; Prabhakara, Rashmi

    2005-03-01

    There has been an exponential growth in the amount of image data that is available on the World Wide Web since the early development of Internet. With such a large amount of information and image available and its usefulness, an effective image retrieval system is thus greatly needed. In this paper, we present an effective approach with both image matching and indexing techniques that improvise on existing integrated image retrieval methods. This technique follows a two-phase approach, integrating query by topic and query by example specification methods. In the first phase, The topic-based image retrieval is performed by using an improved text information retrieval (IR) technique that makes use of the structured format of HTML documents. This technique consists of a focused crawler that not only provides for the user to enter the keyword for the topic-based search but also, the scope in which the user wants to find the images. In the second phase, we use query by example specification to perform a low-level content-based image match in order to retrieve smaller and relatively closer results of the example image. From this, information related to the image feature is automatically extracted from the query image. The main objective of our approach is to develop a functional image search and indexing technique and to demonstrate that better retrieval results can be achieved.

  10. 76 FR 53475 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    .... Your comments should focus on issues specific to the list of topics that we have proposed to the Committee. The list of research topics to be discussed at the meeting will be available on the following Web... disease. Background information about this topic, including panel materials, is available at http://www...

  11. 78 FR 13059 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-26

    ... request to speak by April 1, 2013. Your comments should focus on issues specific to the list of topics that we have proposed to the Committee. The list of research topics to be discussed at the meeting will... clinical significance). Background information about this topic, including panel materials, is available at...

  12. 75 FR 73094 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ... available. Your comments should focus on issues specific to the list of topics that we have proposed to the Committee. The list of research topics to be discussed at the meeting will be available on the following Web... (CKD) patients (pre- dialysis and dialysis). Background information about this topic, including panel...

  13. 77 FR 53204 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    .... Your comments should focus on issues specific to the list of topics that we have proposed to the Committee. The list of research topics to be discussed at the meeting will be available on the following web... management of heart failure. Background information about this topic, including panel materials, is available...

  14. 76 FR 71569 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ... December 22, 2011. Your comments should focus on issues specific to the list of topics that we have proposed to the Committee. The list of research topics to be discussed at the meeting will be available on... atherosclerosis. Background information about this topic, including panel materials, is available at http://www...

  15. [Prioritisation of topics for systematic reviews in hand surgery. Results of an expert survey].

    PubMed

    Schädel-Höpfner, M; Diener, M K; Eisenschenk, A; Lögters, T; Windolf, J

    2011-02-01

    Systematic reviews are fundamental decision-making tools for the assessment of the effectiveness of healthcare interventions and for determining future research fields. In the field of hand surgery, so far, there exists only a limited number of systematic reviews. According to the diversity and multitude of hand surgical topics, relevant fields for systematic reviews were identified by means of an expert ranking. A catalogue of 24 topics was extracted from publications of representative hand surgical journals. These topics were categorized and integrated into a questionnaire which was presented to 30 experts in the field of hand surgery. Every single topic had to be rated by marks from 1 (very relevant) to 5 (not relevant). Further topics could have been indicated. Averaging of the marks allowed to define a ranking and a prioritisation of the topics. 29 of 30 questionnaires were returned. The ranking showed scapholunate ligament injury, Kienboeck's disease and scaphoid nonunion to have the highest relevance, followed by 5 other topics dealing with wrist problems. The lowest relevance was attributed to neck fractures of the fifth metacarpal, ulnar collateral ligament injury of the thumb metacarpophalangeal joint and postoperative management following replantation. The results of the presented survey allow for a prioritisation of topics for systematic reviews in hand surgery. The ranking of the topics emphasises the particular relevance of injuries and diseases of the wrist. © Georg Thieme Verlag KG Stuttgart · New York.

  16. 76 FR 53940 - Notice of Public Meeting; Western Montana Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-30

    ... management in Montana. During these meetings the council will participate in/discuss/act upon several topics... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLMTB07900 09 L10100000.PH0000 LXAMANMS0000] Notice of Public Meeting; Western Montana Resource Advisory Council AGENCY: Bureau of Land Management...

  17. Islet cell research brings hope for a diabetes cure: meeting report from the 6(th) annual islet society meeting in Stellenbosch, South Africa.

    PubMed

    Tchokonte-Nana, V; Cockburn, I L; Manda, J K; Kotze, P C; Johnson, J D

    2014-01-01

    The International Diabetes Federation predicts that, over the next twenty years, the largest increase in the prevalence of diabetes will be in the Africa region. Recognizing an unmet need for more focus on Africa and engagement with African scholars, the Islet Society held its 6th annual meeting July 20-21, 2014 in Stellenbosch, South Africa. Here, we present a report that covers the presentations and discussion points from that meeting. Work was presented on a variety of topics and included presentations by a significant proportion of Africa diabetes researchers. Overall, it was an excellent conference, with many new international collaborations initiated. We hope that other groups will also respond to the need for more conferences in Africa and focused on Africa.

  18. EDITORIAL: Nano Meets Spectroscopy Nano Meets Spectroscopy

    NASA Astrophysics Data System (ADS)

    Birch, David J. S.

    2012-08-01

    The multidisciplinary two-day Nano Meets Spectroscopy (NMS) event was held at the National Physical Laboratory (NPL), Teddington, UK, in September 2011. The event was planned from the outset to be at the interface of several areas—in particular, spectroscopy and nanoscience, and to bring together topics and people with different approaches to achieving common goals in biomolecular science. Hence the meeting cut across traditional boundaries and brought together researchers using diverse techniques, particularly fluorescence and Raman spectroscopy. Despite engaging common problems, these techniques are frequently seen as mutually exclusive with the two communities rarely interacting at conferences. The meeting was widely seen to have lived up to its billing in good measure. It attracted the maximum capacity of ~120 participants, including 22 distinguished speakers (9 from outside the UK), over 50 posters and a vibrant corporate exhibition comprising 10 leading instrument companies and IOP Publishing. The organizers were Professor David Birch (Chair), Dr Karen Faulds and Professor Duncan Graham of the University of Strathclyde, Professor Cait MacPhee of the University of Edinburgh and Dr Alex Knight of NPL. The event was sponsored by the European Science Foundation, the Institute of Physics, the Royal Society of Chemistry, NPL and the Scottish Universities Physics Alliance. The full programme and abstracts are available at http://sensor.phys.strath.ac.uk/nms/program.php. The programme was quite ambitious in terms of the breadth and depth of scope. The interdisciplinary and synergistic concept of 'X meets Y' played well, cross-fertilization between different fields often being a source of inspiration and progress. Fluorescence and Raman spectroscopy provided the core, but the meeting had little repetition and also attracted contributions on more specialist techniques such as CARS, super-resolution, single molecule and chiral methods. In terms of application the

  19. ECBS & ICBS 2015 Joint Meeting: Bringing Chemistry to Life.

    PubMed

    Varon Silva, Daniel

    2016-03-15

    The European Chemical Biology Society (ECBS) and the International Chemical Biology Society (ICBS) recently organized a joint meeting in Berlin. This meeting had more than 250 participants. Four keynote lectures were given by Timothy Mitchison, David Tirrell, Carolyn Bertozzi and Jason Chin; in addition there were 13 invited speakers, 20 selected oral talks and 30 talks selected from 90 posters. The meeting was divided into six topics: chemoproteomics, epigenetics, conjugates for target delivering, anti-infectives, molecular imaging and probing the structure, and function of post-translational modifications. The highlights of the meeting are presented in this report. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Minoxidil topical solution: an unsafe product for children.

    PubMed

    Claudet, Isabelle; Cortey, Caroline; Honorat, Raphaele; Franchitto, Nicolas

    2015-01-01

    Minoxidil hair formulation is commonly used for the treatment of male or female androgenic alopecia. This over-the-counter product is wrongly considered safe. The ingestion of a few milliliters by a child can lead to significant intoxication. We report a case of significant intoxication after the ingestion of topical minoxidil (Alopexy; Pierre Fabre Laboratoires, SA, Switzerland). A 7-year-old girl, who accidentally ingested a teaspoon of minoxidil hair solution, presented to the pediatric emergency department for emesis. At admission, she had a blood pressure of 86/56 mm Hg and a pulse of 149 beats per minute. Hypotension lasted 40 hours with the lowest value 24 hours after ingestion (79/33 mm Hg). She presented electrocardiogram changes (sinus tachycardia and flattening T-waves) but normal cardiac enzymes. Infusion of 20 mL/kg of normal saline fluid had no hemodynamic effect. Her blood pressure normalized on day 2. Minoxidil topical solution is an unsafe product for children. This formulation should be strictly kept out of reach of children and manufacturers should enhance child-resistance security of packaging. The over-the-counter availability must be questioned.

  1. 76 FR 13418 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ... April 15, 2011. Your comments should focus on issues specific to the list of topics that we have proposed to the Committee. The list of research topics to be discussed at the meeting will be available on... information about this topic, including panel materials, is available at http://www.cms.gov/medicare-coverage...

  2. 77 FR 64997 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... focus on issues specific to the list of topics that we have proposed to the Committee. The list of research topics to be discussed at the meeting will be available on the following Web site prior to the... neurodegenerative disease. Background information about this topic, including panel materials, is available at http...

  3. 75 FR 8980 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... available. Your comments should focus on issues specific to the list of topics that we have proposed to the Committee. The list of research topics to be discussed at the meeting will be available on the following Web... prostate cancer. Background information about this topic, including panel materials, is available at http...

  4. 76 FR 10064 - Notice of Public Meeting of the Central California Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ... associated with public land management in Central California. At this meeting, agenda topics will include an update on Resource Management Plans and other resource management issues. Additional ongoing business... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLCAC01000 L10100000.XZ0000 LXSIOVHD0000...

  5. 75 FR 32375 - New England Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-08

    ...: (978) 465-0492. SUPPLEMENTARY INFORMATION: Tuesday, June 22, 2010 Following introductions and any... the Scientific and Statistical Committee's (SSC) report on its most recent meeting. The SSC's topics...

  6. AACR Annual Meeting 2008: autophagy in the forefront of cancer research.

    PubMed

    Karantza-Wadsworth, Vassiliki

    2008-07-01

    The 2008 American Association for Cancer Research (AACR) Annual Meeting was held in San Diego, CA, April 12-16, 2008 (http:// www.aacr.org/home/scientists/meetings--workshops/annual-meeting-2008.aspx). More than 17,000 scientists from 60 countries participated in this meeting that was organized by AACR, the oldest and largest organization in the world focused on cancer research. The scientific presentations included more than 6,000 abstracts and 500 invited talks on new and significant discoveries in basic, clinical, and translational cancer research. Autophagy, as pertaining to tumorigenesis and response to anticancer therapies, was undoubtedly a "hot topic" in this meeting. An educational session, a forum, a minisymposium and several other talks dispersed in different sessions had a strong focus on autophagy. All autophagy-related presentations were very well attended and stimulated lively discussions, clearly indicating that the scientific community is greatly interested in this rapidly-progressing area of research.

  7. AACR Annual Meeting 2008: Autophagy in the forefront of cancer research.

    PubMed

    Karantza, Vassiliki

    2008-07-01

    The 2008 American Association for Cancer Research (AACR) Annual Meeting was held in San Diego, CA, April 12-16, 2008 (http:// www.aacr.org/home/scientists/meetings--workshops/annual-meeting-2008.aspx). More than 17,000 scientists from 60 countries participated in this meeting that was organized by AACR, the oldest and largest organization in the world focused on cancer research. The scientific presentations included more than 6,000 abstracts and 500 invited talks on new and significant discoveries in basic, clinical, and translational cancer research. Autophagy, as pertaining to tumorigenesis and response to anticancer therapies, was undoubtedly a "hot topic" in this meeting. An educational session, a forum, a minisymposium and several other talks dispersed in different sessions had a strong focus on autophagy. All autophagy-related presentations were very well attended and stimulated lively discussions, clearly indicating that the scientific community is greatly interested in this rapidly-progressing area of research.

  8. Topical Coconut Oil in Very Preterm Infants: An Open-Label Randomised Controlled Trial.

    PubMed

    Strunk, Tobias; Pupala, Sameer; Hibbert, Julie; Doherty, Dorota; Patole, Sanjay

    2018-01-01

    The immature fragile skin of preterm infants represents an inadequate protective barrier. The emollient and anti-infective properties of coconut oil make it a potentially beneficial topical agent for this population. Our aim was to evaluate feasibility, safety, and the effects of topical coconut oil on skin condition in very preterm infants. An open-label randomised controlled trial in preterm infants <30 weeks' gestation was conducted. Enrolled infants were randomised to receive either routine care or topical coconut oil (5 mL/kg) twice daily for 21 days, starting within 24 h of birth. The neonatal skin condition was the primary outcome, and was assessed using the Neonatal Skin Condition Score (NSCS) on days 1, 7, 14, and 21. The number of coconut oil applications was recorded to assess clinical feasibility and all enrolled infants were monitored for adverse effects of topical coconut application, such as skin irritation. A total of 72 infants born <30 weeks' gestation were enrolled (36 infants per arm), with comparable demographic characteristics. Topical application of coconut oil was feasible and without adverse effects. The NSCS was maintained in the coconut oil group throughout the intervention period, but deteriorated from a median (IQR) of 3 (3-4) on day 1 to 4 (4-4) on day 21 in the control group (p = 0.01). There were no differences in common neonatal outcomes, including sepsis, necrotising enterocolitis, retinopathy of prematurity, chronic lung disease, and mortality. Topical coconut oil maintained a better skin condition in very preterm infants without adverse effects. This simple, safe, and affordable intervention warrants further investigation. © 2017 S. Karger AG, Basel.

  9. Nineteenth International Microgravity Measurements Group Meeting

    NASA Technical Reports Server (NTRS)

    DeLombard, Richard (Compiler)

    2000-01-01

    The Microgravity Measurements Group meetings provide a forum for an exchange of information and ideas about various aspects of microgravity acceleration research in international microgravity research programs. These meetings are sponsored by the PI Microgravity Services (PIMS) project at the NASA Glenn Research Center. The 19th MGMG meeting was held 11-13 July 2000 at the Sheraton Airport Hotel in Cleveland, Ohio. The 44 attendees represented NASA, other space agencies, universities, and commercial companies; 8 of the attendees were international representatives from Japan, Italy, Canada, Russia, and Germany. Twenty-seven presentations were made on a variety of microgravity environment topics including the International Space Station (ISS), acceleration measurement and analysis results, science effects from microgravity accelerations, vibration isolation, free flyer satellites, ground testing, vehicle characterization, and microgravity outreach and education. The meeting participants also toured three microgravity-related facilities at the NASA Glenn Research Center. Contained within the minutes is the conference agenda, which indicates each speaker, the title of their presentation, and the actual time of their presentation. The minutes also include the charts for each presentation, which indicate the authors' name(s) and affiliation. In some cases, a separate written report was submitted and has been Included here

  10. 75 FR 58414 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... focus on issues specific to the list of topics that we have proposed to the Committee. The list of research topics to be discussed at the meeting will be available on the following Web site prior to the... topic, including panel materials, is available at http://www.cms.hhs.gov/center/coverage.asp . We...

  11. Insights from a Recent Meeting: Current Status and Future Directions in Magnesium Corrosion Research

    DOE PAGES

    Brady, Michael P.; Joost, William J.; David Warren, C.

    2016-11-17

    The United States Department of Energy Vehicle Technologies Office held a Technical Review Meeting entitled “Current Status and Future Directions in Magnesium Corrosion Research” at Oak Ridge National Laboratory in April 2016. Here current funded Mg corrosion projects presented their latest results, along with invited presentations from academic and industrial researchers in the area of Mg corrosion. This paper overviews select topics from the meeting, with an emphasis on relaying meeting discussion points regarding future needs in understanding and mitigating Mg corrosion, particularly for automotive applications. Topics highlighted include the need for pretreatments and coatings suitable for mass vehicle productionmore » of Mg components, particularly for dissimilar metal joints involving Mg, Al, or steel, and corrosion evaluation methods more relevant to automotive components and operating conditions. Finally, from a scientific perspective, the need for better fundamental understanding of Mg dissolution, hydrogen evolution, and film formation behavior was a recurring theme, as was phenomena related to microgalvanic coupling involving second phases and impurities in Mg.« less

  12. Insights from a Recent Meeting: Current Status and Future Directions in Magnesium Corrosion Research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brady, Michael P.; Joost, William J.; David Warren, C.

    The United States Department of Energy Vehicle Technologies Office held a Technical Review Meeting entitled “Current Status and Future Directions in Magnesium Corrosion Research” at Oak Ridge National Laboratory in April 2016. Here current funded Mg corrosion projects presented their latest results, along with invited presentations from academic and industrial researchers in the area of Mg corrosion. This paper overviews select topics from the meeting, with an emphasis on relaying meeting discussion points regarding future needs in understanding and mitigating Mg corrosion, particularly for automotive applications. Topics highlighted include the need for pretreatments and coatings suitable for mass vehicle productionmore » of Mg components, particularly for dissimilar metal joints involving Mg, Al, or steel, and corrosion evaluation methods more relevant to automotive components and operating conditions. Finally, from a scientific perspective, the need for better fundamental understanding of Mg dissolution, hydrogen evolution, and film formation behavior was a recurring theme, as was phenomena related to microgalvanic coupling involving second phases and impurities in Mg.« less

  13. Minutes of the Sixth CEOS Plenary Meeting

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The Committee on Earth Observations Satellites (CEOS) minutes for the sixth plenary meeting held in London, December 9-11, 1992 are presented. Attending as prospective members were the Russian Space Agency (RSA), the Committee for Hydrometeorology and Environmental Monitoring of the Ministry for Ecology and Natural resources of the Russian Federation (ROSCOMGIDROMET), the Chinese Academy of Space Technology (CAST) and the National Remote Sensing Center of China (NRSCC). Actions taken at the meeting included membership issues, CEOS proposals, data policy, and working group reports. Data requirements of CEOS affiliates were also reported on. Additional summations and statements as well as lists of participants and future meetings are included. In general, topics covered related to remote sensing and global change.

  14. 76 FR 66880 - Negotiated Rulemaking Committee, Negotiator Nominations and Schedule of Committee Meetings...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... are significantly affected by the topics proposed for negotiation. We request nominations for... locations of the committee meetings are set out in the Schedule for Negotiations section under SUPPLEMENTARY... topics proposed for negotiations. In so doing, we will follow the requirement in Section 492(b)(1) of the...

  15. Flash Updates of GSC projects (GSC8 Meeting)

    ScienceCinema

    Glockner, Frank Oliver; Markowitz, Victor; Kyrpides, Nikos; Meyer, Folker; Amaral-Zettler, Linda; Cole, James

    2018-01-25

    The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding Research Coordination Network from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. In quick succession Frank Oliver Glockner (MPI-Bremen), Victor Markowitz (LBNL), Nikos Kyripides (JGI), Folker Meyer (ANL), Linda Amaral-Zettler (Marine Biology Lab), and James Cole (Michigan State University) provide updates on a number of topics related to GSC projects at the Genomic Standards Consortium 8th meeting at the DOE JGI in Walnut Creek, CA on Sept. 9, 2009.

  16. Flash Updates of GSC projects (GSC8 Meeting)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Glockner, Frank Oliver; Markowitz, Victor; Kyrpides, Nikos

    2009-09-09

    The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding Research Coordination Network from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. In quick succession Frank Oliver Glockner (MPI-Bremen), Victor Markowitz (LBNL), Nikos Kyripides (JGI), Folker Meyer (ANL), Linda Amaral-Zettler (Marine Biology Lab), and James Colemore » (Michigan State University) provide updates on a number of topics related to GSC projects at the Genomic Standards Consortium 8th meeting at the DOE JGI in Walnut Creek, CA on Sept. 9, 2009.« less

  17. 75 FR 29538 - SFIREG Full Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group.... This notice announces the location and times for the meeting and sets forth the tentative agenda topics...

  18. Topic Model for Graph Mining.

    PubMed

    Xuan, Junyu; Lu, Jie; Zhang, Guangquan; Luo, Xiangfeng

    2015-12-01

    Graph mining has been a popular research area because of its numerous application scenarios. Many unstructured and structured data can be represented as graphs, such as, documents, chemical molecular structures, and images. However, an issue in relation to current research on graphs is that they cannot adequately discover the topics hidden in graph-structured data which can be beneficial for both the unsupervised learning and supervised learning of the graphs. Although topic models have proved to be very successful in discovering latent topics, the standard topic models cannot be directly applied to graph-structured data due to the "bag-of-word" assumption. In this paper, an innovative graph topic model (GTM) is proposed to address this issue, which uses Bernoulli distributions to model the edges between nodes in a graph. It can, therefore, make the edges in a graph contribute to latent topic discovery and further improve the accuracy of the supervised and unsupervised learning of graphs. The experimental results on two different types of graph datasets show that the proposed GTM outperforms the latent Dirichlet allocation on classification by using the unveiled topics of these two models to represent graphs.

  19. 75 FR 6202 - Notice of Open Meeting of the Environmental Financial Advisory Board (EFAB)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-08

    ... funding environmental programs, projects, and activities. The purpose of the meeting is to hear from... progress with work projects under EFAB's current Strategic Action Agenda. Environmental Finance topics... Reduction; Innovative Financing Tools, and State Revolving Fund Investment Options. The meeting is open to...

  20. The 1990 Western Pacific Geophysics meeting

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The 1990 Western Pacific Geophysics Meeting was held in Kanazawa, Japan from 15-21 Aug. 1990. This was the first meeting of a new series of meetings for the American Geophysical Union, and it proved to be very successful in terms of the scientific program and attendance, which included over 1,000 participants. The intent of this meeting was an effort on the part of the American Geophysical Union (AGU) and several Japanese geophysical societies to gather individual Earth and space scientists at a major scientific meeting to focus on geophysical problems being studied in the western Pacific rim. The meeting was organized along the lines of a typical AGU annual meeting with some invited talks, many contributed talks, poster sessions, and with emphasis on presentations and informal discussions. The program committee consisted of scientists from both the U.S. and Japan. This meeting provided ample opportunities for U.S. and Japanese scientists to get to know each other and their works on a one-to-one basis. It was also a valuable opportunity for students studying geophysics to get together and interact with each other and with scientists from both the U.S. and Japan. There were 939 abstracts submitted to the conference and a total of 102 sessions designed as a result of the abstracts received. The topics of interest are as follows: space geodetic and observatory measurements for earthquake and tectonic studies; gravity, sea level, and vertical motion; variations in earth rotation and earth dynamics; sedimentary magnetism; global processes and precipitation; subsurface contaminant transport; U.S. Western Pacific Rim initiatives in hydrology; shelf and coastal circulation; tectonics, magmatism, and hydrothermal processes; earthquake prediction and hazard assessment; seismic wave propagation in realistic media; and dynamics and structure of plate boundaries and of the Earth's deep interior.

  1. Public, experts join at town meeting

    NASA Astrophysics Data System (ADS)

    Bush, Susan

    About 80 citizens concerned with the threat of ozone depletion attended a public meeting on June 9 in Charlottesville, Va., to discuss the issue with a panel of six leading ozone experts. Held in conjunction with the Quadrennial Ozone Symposium, the town meeting was videotaped for airing on public broadcast stations this fall. The meeting was aimed at nonexperts, to “get the word out” to the public, said the moderator, journalist Peter Hackes.The lively, sometimes heated discussion showed the public's high awareness and concern over problems associated with ozone depletion. During the nearly 2-hour meeting topics ranged from the reparability of the ozone layer, to steps the public can take to help mitigate ozone loss, to reports of increased cases of skin cancer due to more ultraviolet radiation reaching the Earth's surface. There were also some claims that ozone depletion is overexaggerated and is a hoax for scientists to get more research funding.

  2. 77 FR 65380 - 2012 Fall Joint Meeting of the Ozone Transport Commission and the Mid-Atlantic Northeast...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9745-9] 2012 Fall Joint Meeting of the Ozone Transport... Fall Meeting of the Ozone Transport Commission (OTC) and the Mid-Atlantic Northeast Visibility Union (MANE- VU). The meeting agenda will include topics regarding reducing ground- level ozone precursors and...

  3. Immunotherapies in transplantation and cancer: 22nd NAT meeting/2nd NAT LabEx IGO joint meeting; 1-2 June 2017, Nantes, France.

    PubMed

    Simon, Sylvain; Charpentier, Maud; Anegon, Ignacio; Labarriere, Nathalie

    2017-09-01

    This 22nd edition of the Nantes Actualités Transplantation annual meeting was co-organized for the second time with the LabEx Immuno-Graft Oncology network. This international meeting was held on 1 and 2 June 2017 in Nantes (western France). The topic of this 2-day meeting was 'Immunotherapies in transplantation and cancer'. This meeting brought together 17 international invited speakers, young researchers and 220 attendees mainly from Europe and North America. It was a unique opportunity to bring together the pioneers and leading immunologists in the fields of transplantation and cancer, focusing on shared mechanisms that control immune responses in organ or bone marrow transplantation and in cancer.

  4. GeneTopics - interpretation of gene sets via literature-driven topic models

    PubMed Central

    2013-01-01

    Background Annotation of a set of genes is often accomplished through comparison to a library of labelled gene sets such as biological processes or canonical pathways. However, this approach might fail if the employed libraries are not up to date with the latest research, don't capture relevant biological themes or are curated at a different level of granularity than is required to appropriately analyze the input gene set. At the same time, the vast biomedical literature offers an unstructured repository of the latest research findings that can be tapped to provide thematic sub-groupings for any input gene set. Methods Our proposed method relies on a gene-specific text corpus and extracts commonalities between documents in an unsupervised manner using a topic model approach. We automatically determine the number of topics summarizing the corpus and calculate a gene relevancy score for each topic allowing us to eliminate non-specific topics. As a result we obtain a set of literature topics in which each topic is associated with a subset of the input genes providing directly interpretable keywords and corresponding documents for literature research. Results We validate our method based on labelled gene sets from the KEGG metabolic pathway collection and the genetic association database (GAD) and show that the approach is able to detect topics consistent with the labelled annotation. Furthermore, we discuss the results on three different types of experimentally derived gene sets, (1) differentially expressed genes from a cardiac hypertrophy experiment in mice, (2) altered transcript abundance in human pancreatic beta cells, and (3) genes implicated by GWA studies to be associated with metabolite levels in a healthy population. In all three cases, we are able to replicate findings from the original papers in a quick and semi-automated manner. Conclusions Our approach provides a novel way of automatically generating meaningful annotations for gene sets that are directly

  5. APTWG: The 4th Asia-Pacific Transport Working Group Meeting

    NASA Astrophysics Data System (ADS)

    Ida, K.; Kwon, J. M.; Leconte, M.; Ko, W. H.; Inagaki, S.; Todo, Y.; Kosuga, Y.

    2015-01-01

    This conference report summarizes the contributions to, and discussions at, the 4th Asia-Pacific Transport Working Group Meeting held at Kyushu University, Japan, during 10-13 June 2014. The topics of the meeting were organized under five main headings: turbulence suppression and transport barrier formation, effect of magnetic topology on MHD activity and transport, non-diffusive contribution of momentum and particle transport, non-local transport and turbulence spreading and coupling, energetic particles and instability. The Young Researchers' Forum which was held in this meeting is also described in this report.

  6. 76 FR 78944 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-20

    ...The National Geospatial Advisory Committee (NGAC) will meet on January 12, 2012, from 1 p.m. to 4 p.m. EST. The meeting will be held via Web conference and teleconference. The NGAC, which is composed of representatives from governmental, private sector, non-profit, and academic organizations, has been established to advise the Chair of the Federal Geographic Data Committee on management of Federal geospatial programs, the development of the National Spatial Data Infrastructure, and the implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include:

  7. 76 FR 13660 - Notice of Public Meeting, BLM-Alaska Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... management planning Other topics of interest to the RAC All meetings are open to the public. Depending on the... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLAK910000-L13100000.PP0000-L.X.SS.052L0000] Notice of Public Meeting, BLM-Alaska Resource Advisory Council AGENCY: Bureau of Land Management, Alaska...

  8. Public meeting: Western New York Nuclear Service Center options study. [Problem of West Valley plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    This document is a transcript of the meeting, with additional written comments. The main topic is the West Valley Processing Plant and how to dispose of it and its high-level wastes. Objective is to get public input on this topic. (DLC)

  9. IFPA Meeting 2011 workshop report III: Placental immunology; epigenetic and microRNA-dependent gene regulation; comparative placentation; trophoblast differentiation; stem cells☆

    PubMed Central

    Ackerman, W.E.; Bulmer, J.N.; Carter, A.M.; Chaillet, J.R.; Chamley, L.; Chen, C.P.; Chuong, E.B.; Coleman, S.J.; Collet, G.P.; Croy, B.A.; de Mestre, A.M.; Dickinson, H.; Ducray, J.; Enders, A.C.; Fogarty, N.M.E.; Gauster, M.; Golos, T.; Haider, S.; Heazell, A.E.; Holland, O.J.; Huppertz, B.; Husebekk, A.; John, R.M.; Johnsen, G.M.; Jones, C.J.P.; Kalionis, B.; König, J.; Lorenzon, A.R.; Moffett, A.; de Mello, J.C. Moreira; Nuzzo, A.M.; Parham, P.; Parolini, O.; Petroff, M.G.; Pidoux, G.; Ramírez-Pinilla, M.P.; Robinson, W.P.; Rolfo, A.; Sadovsky, Y.; Soma, H.; Southcombe, J.H.; Tilburgs, T.; Lash, G.E.

    2014-01-01

    Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialised topics. At IFPA meeting 2011 there were twelve themed workshops, five of which are summarized in this report. These workshops related to various aspects of placental biology: 1) immunology; 2) epigenetics; 3) comparative placentation; 4) trophoblast differentiation; 5) stem cells. PMID:22154501

  10. The Science and Engineering Talent Pool. Proceedings of the Joint Meeting of the Scientific Manpower Commission and the Engineering Manpower Commission (Washington, District of Columbia, May 15, 1984).

    ERIC Educational Resources Information Center

    Scientific Manpower Commission, Washington, DC.

    The proceedings of a meeting which focused on topics and issues related to the pipeline for scientists and engineers are presented. They include the meeting agenda, introductory comments, an overview, summaries of five presentations, the meeting summary, and a list of participants. The overview (by Betty Vetter) outlines some ways of measuring the…

  11. The 1997 JANNAF Propellant Development and Characterization Subcommittee and Safety and Environmental Protection Subcommittee Joint Meeting

    NASA Technical Reports Server (NTRS)

    Cocchiaro, James E. (Editor); Filliben, Jeff D. (Editor); Watson, Anne H. (Editor)

    1997-01-01

    In the Propellant Development and Characterization Subcommittee (PDCS) meeting, topics included: the analysis, characterization, and processing of propellants and propellant ingredients; chemical reactivity; liquid propellants; test methods; rheology; surveillance and aging; and process engineering. In the Safety and Environmental Protection Subcommittee (S&EPS) meeting, topics covered included: hydrazine propellant vapor detection methods; toxicity of propellants and propellants; explosives safety; atmospheric modeling and risk assessment of toxic releases; reclamation, disposal, and demilitarization methods; and remediation of explosives or propellant contaminated sites.

  12. 75 FR 3199 - Agenda and Notice of Public Meetings of the Massachusetts Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... COMMISSION ON CIVIL RIGHTS Agenda and Notice of Public Meetings of the Massachusetts Advisory.... Commission on Civil Rights and the Federal Advisory Committee Act, that orientation, planning and briefing... briefing meeting is hear presentations from expert(s) about topical civil rights issues. Members of the...

  13. Identifying Topics in Microblogs Using Wikipedia.

    PubMed

    Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan

    2016-01-01

    Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail.

  14. Identifying Topics in Microblogs Using Wikipedia

    PubMed Central

    Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan

    2016-01-01

    Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail. PMID:26991442

  15. 21st Nantes Actualités Transplantation: "When Stem Cells Meet Immunology".

    PubMed

    Anegon, Ignacio; Nguyen, Tuan Huy

    2017-01-01

    "When Stem Cells Meet Immunology" has been the topic of the 21st annual "Nantes Actualités en Transplantation" meeting (June 9-10, 2016, Nantes, France). This meeting brought together pioneers and leading experts in the fields of stem cells, biomaterials and immunoregulation. Presentations covered multipotent (mesenchymal and hematopoietic) and pluripotent stem cells (embryonic and induced) for regenerative medicine of incurable diseases, immunotherapy and blood transfusions. An additional focus had been immune rejections and responses of allogeneic or autologous stem cells. Conversely, stem cells are also able to directly modulate the immune response through the production of immunoregulatory molecules. Moreover, stem cells may also provide an unlimited source of immune cells (DCs, NK cells, B cells, and T cells) that can operate as "super" immune cells, for example, through genetic engineering with chimeric antigen receptors.This meeting report puts presentations into an overall context highlighting new potential biomarkers for potency prediction of mesenchymal stem cell-derived and pluripotent stem cell-derived multicellular organoids. Finally, we propose future directions arising from the flourishing encounter of stem cell and immune biology.

  16. Mining FDA drug labels using an unsupervised learning technique--topic modeling.

    PubMed

    Bisgin, Halil; Liu, Zhichao; Fang, Hong; Xu, Xiaowei; Tong, Weida

    2011-10-18

    The Food and Drug Administration (FDA) approved drug labels contain a broad array of information, ranging from adverse drug reactions (ADRs) to drug efficacy, risk-benefit consideration, and more. However, the labeling language used to describe these information is free text often containing ambiguous semantic descriptions, which poses a great challenge in retrieving useful information from the labeling text in a consistent and accurate fashion for comparative analysis across drugs. Consequently, this task has largely relied on the manual reading of the full text by experts, which is time consuming and labor intensive. In this study, a novel text mining method with unsupervised learning in nature, called topic modeling, was applied to the drug labeling with a goal of discovering "topics" that group drugs with similar safety concerns and/or therapeutic uses together. A total of 794 FDA-approved drug labels were used in this study. First, the three labeling sections (i.e., Boxed Warning, Warnings and Precautions, Adverse Reactions) of each drug label were processed by the Medical Dictionary for Regulatory Activities (MedDRA) to convert the free text of each label to the standard ADR terms. Next, the topic modeling approach with latent Dirichlet allocation (LDA) was applied to generate 100 topics, each associated with a set of drugs grouped together based on the probability analysis. Lastly, the efficacy of the topic modeling was evaluated based on known information about the therapeutic uses and safety data of drugs. The results demonstrate that drugs grouped by topics are associated with the same safety concerns and/or therapeutic uses with statistical significance (P<0.05). The identified topics have distinct context that can be directly linked to specific adverse events (e.g., liver injury or kidney injury) or therapeutic application (e.g., antiinfectives for systemic use). We were also able to identify potential adverse events that might arise from specific

  17. Multidisciplinary molecular diagnostics: the 9th European meeting on molecular diagnostics.

    PubMed

    Loonen, Anne J M; Schuurman, Rob; van den Brule, Adriaan J C

    2016-01-01

    This report presents a summary of the 9th European Meeting on Molecular Diagnostics held in Noordwijk, The Netherlands, 14-16 October 2015. This 3-day conference covered many relevant topics in the field of molecular diagnostics in humans, including infectious disease, oncology, outbreak management, population-based cancer screening, standardization and quality control, chronic diseases and pharmacogenetics. Beyond these different areas, shared values are new technologies and novel technical and clinical applications. Approximately 450 participants, the majority coming from European countries, attended the meeting. Besides high quality scientific presentations, more than 35 diagnostic companies presented their latest innovations, altogether in an informal and inspiring scientific ambience.

  18. Mental Mechanisms for Topics Identification

    PubMed Central

    2014-01-01

    Topics identification (TI) is the process that consists in determining the main themes present in natural language documents. The current TI modeling paradigm aims at acquiring semantic information from statistic properties of large text datasets. We investigate the mental mechanisms responsible for the identification of topics in a single document given existing knowledge. Our main hypothesis is that topics are the result of accumulated neural activation of loosely organized information stored in long-term memory (LTM). We experimentally tested our hypothesis with a computational model that simulates LTM activation. The model assumes activation decay as an unavoidable phenomenon originating from the bioelectric nature of neural systems. Since decay should negatively affect the quality of topics, the model predicts the presence of short-term memory (STM) to keep the focus of attention on a few words, with the expected outcome of restoring quality to a baseline level. Our experiments measured topics quality of over 300 documents with various decay rates and STM capacity. Our results showed that accumulated activation of loosely organized information was an effective mental computational commodity to identify topics. It was furthermore confirmed that rapid decay is detrimental to topics quality but that limited capacity STM restores quality to a baseline level, even exceeding it slightly. PMID:24744775

  19. Air Quality and Heart Health: An Emerging Topic for Heart Month

    EPA Science Inventory

    Air Quality and Heart Health: An Emerging Topic for Heart Month: Ambient air particle pollution increases short- and long-term cardiovascular morbidity and mortality. Older-people, those with pre-existing heart disease and lung disease and diabetes are at higher risk. Mechanism...

  20. 77 FR 72359 - Animal Generic Drug User Fee Act; Public Meeting; Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ... increase the revenue stream stability and reduce application fee costs. III. What information should you...] Animal Generic Drug User Fee Act; Public Meeting; Request for Comments AGENCY: Food and Drug... announcing the following meeting: Animal Generic Drug User Fee Act. The topic to be discussed is proposed...

  1. 77 FR 73497 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on US-APWR...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-10

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on US-APWR; Notice of Meeting The ACRS Subcommittee on US-APWR will hold a meeting on January 15....'' Both Topical Reports are associated with the design certification of the US-APWR. The Subcommittee will...

  2. NASA Physical Sciences - Presentation to Annual Two Phase Heat Transfer International Topical Team Meeting

    NASA Technical Reports Server (NTRS)

    Chiaramonte, Francis; Motil, Brian; McQuillen, John

    2014-01-01

    The Two-phase Heat Transfer International Topical Team consists of researchers and members from various space agencies including ESA, JAXA, CSA, and RSA. This presentation included descriptions various fluid experiments either being conducted by or planned by NASA for the International Space Station in the areas of two-phase flow, flow boiling, capillary flow, and crygenic fluid storage.

  3. 21 CFR 14.22 - Meetings of an advisory committee.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Meetings of an advisory committee. 14.22 Section... of, and with an agenda approved by, the designated Federal employee or alternate. No meeting may be held in the absence of the designated Federal employee. (1) If any matter is added to the agenda after...

  4. 21 CFR 14.22 - Meetings of an advisory committee.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Meetings of an advisory committee. 14.22 Section... of, and with an agenda approved by, the designated Federal employee or alternate. No meeting may be held in the absence of the designated Federal employee. (1) If any matter is added to the agenda after...

  5. 21 CFR 14.22 - Meetings of an advisory committee.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Meetings of an advisory committee. 14.22 Section... of, and with an agenda approved by, the designated Federal employee or alternate. No meeting may be held in the absence of the designated Federal employee. (1) If any matter is added to the agenda after...

  6. 21 CFR 14.22 - Meetings of an advisory committee.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Meetings of an advisory committee. 14.22 Section... of, and with an agenda approved by, the designated Federal employee or alternate. No meeting may be held in the absence of the designated Federal employee. (1) If any matter is added to the agenda after...

  7. 21 CFR 14.22 - Meetings of an advisory committee.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Meetings of an advisory committee. 14.22 Section... of, and with an agenda approved by, the designated Federal employee or alternate. No meeting may be held in the absence of the designated Federal employee. (1) If any matter is added to the agenda after...

  8. Introduction to the special issue from the 2014 meeting of the International Behavioral Neuroscience Society.

    PubMed

    Young, Jared W; Hall, F Scott; Pletnikov, Mikhail; Kent, Stephen

    2015-11-01

    In 2013, President Obama launched what has been optimistically described as the "decade of the brain". The launch of this effort comes on the back of widespread acknowledgement that more is required to aid those suffering from mental health disorders. Specifically, a greater understanding of the neural circuitry related to behaviors specific to mental health disorders is needed. The field of research that relates the circuitry of the brain to specific aspects of behavior is referred to as behavioral neuroscience. The International Behavioral Neuroscience Society (IBNS) was founded in 1992 specifically to meet on an annual basis and present the latest research findings in this field, and to gather together the international research community to discuss issues important for the development and progress of this scientific discipline. This special issue includes reviews of topics of emerging interest and advancing knowledge in behavioral neuroscience, based on symposia presented at the 2014 IBNS meeting. Topics discussed at the annual IBNS meeting ranged from investigations of the neural mechanisms underlying bipolar disorder, schizophrenia, depression, traumatic brain injury, and risk-taking behavior, to behavioral consequences of obesity and immune dysfunction. Novel treatment areas are covered such as the use of deep brain stimulation, as well as investigation of the behavioral impacts of nicotine withdrawal and how this research will influence the development of nicotine cessation treatments. Hence, this special issue covers a wide-range of topics in behavioral neuroscience offering an insight into the challenges faced by researchers in this decade of the brain. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. 76 FR 59190 - Voluntary Service National Advisory Committee; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ...). On October 14, agenda topics will include: Subcommittee reports; review of standard operating procedure revisions; 2013 NAC annual meeting plans; and any new business. No time will be allocated at this...

  10. 78 FR 33429 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C...: Selected Topics in Transfusion Medicine. Date: June 24-25, 2013. Time: 11:30 a.m. to 6:00 p.m. Agenda: To...

  11. Topical Ketamine 10% for Neuropathic Pain in Spinal Cord Injury Patients: An Open-Label Trial.

    PubMed

    Rabi, Joseph; Minori, Joshua; Abad, Hasan; Lee, Ray; Gittler, Michelle

    2016-01-01

    Topical ketamine, an N-methyl-D-aspartate antagonist, has been shown to be effective in certain neuropathic pain syndromes. The objective of this study was to determine the efficacy of topical ketamine in spinal cord injury patients with neuropathic pain. An open label trial enrolled five subjects at an outpatient rehabilitation hospital with traumatic spinal cord injuries who had neuropathic pain at or below the level of injury. Subjects applied topical ketamine 10% three times a day for a two-week duration. Subjects recorded their numerical pain score-ranging from 0 to 10, with 0 representing "no pain, 5 representing "moderate pain," and 10 being described as "worst possible pain"-in a journal at the time of application of topical ketamine and one hour after application. Using a numerical pain scale allows for something as subjective as pain to be given an objective quantification. Subjects also recorded any occurrence of adverse events and level of satisfaction. All five subjects had a decrease in their numerical pain scale by the end of two weeks, ranging from 14% to 63%. The duration ranged from one hour in one subject to the next application in other subjects. There were no adverse effects. Overall, four out of the five subjects stated they were satisfied. Topical ketamine 10% is an effective neuropathic pain medicine in patients with spinal cord injuries; however, further studies need to be done with a placebo and larger sample size. Copyright© by International Journal of Pharmaceutical Compounding, Inc.

  12. International VLBI Service for Geodesy and Astrometry: 2000 General Meeting Proceedings

    NASA Technical Reports Server (NTRS)

    Vandenberg, Nancy R. (Editor); Baver, Karen D. (Editor)

    2000-01-01

    This volume is the proceedings of the first General Meeting of the International Very Long Base Interferometry (VLBI) Service for Geodesy and Astrometry (IVS), held in Koetzting, Germany, February 21-24, 2000. The content of this volume also appears on the IVS web site at: http://ivscc.gsfc.nasa.gov/publications/gm2000. The goal of the program committee for the General Meeting was to provide an interesting and informative program for a wide cross section of IVS members, including station operators, program managers, and analysts. The program included reports, tutorials, invited and contributed papers, and poster presentations. The tutorial papers should be particularly useful references because each one provides an overview and introduction to a topic relevant to VLBI.

  13. 75 FR 36663 - Notice of Meeting of the Advisory Committee on Commercial Operations of Customs and Border...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... teleconference. The meeting is limited to one topic, the 2010 National Strategy for Global Supply Chain Security... COAC will meet to discuss its views on the development of the 2010 National Strategy for Global Supply Chain Security. Public Participation: This meeting is open to the public; however, participation in COAC...

  14. Topical Issue on Optical Particle Characterization and Remote Sensing of the Atmosphere: Part I

    NASA Technical Reports Server (NTRS)

    Videen, Gorden; Kocifaj, Miroslav; Sun, Wenbo; Kai, Kenji; Kawamoto, Kazuaki; Horvath, Helmuth; Mishchenko, Michael

    2015-01-01

    Increasing our understanding of the Earth-atmosphere system has been a scientific and political priority for the last few decades. This system not only touches on environmental science, but it has applicability to our broader understanding of planetary atmospheres in general. While this issue focuses primarily on electromagnetics, other fundamental fields of science, including fluid and thermodynamics play major roles. In recent years, significant research efforts have led to advances in the fields of radiative transfer and electromagnetic scattering from irregularly shaped particles. Recently, several workshops and small conferences have taken place to promote the fusion of these efforts. Late in 2013, for instance, two such meetings took place. The Optical Characterization of Atmospheric Aerosols (OCAA) meeting took place in Smolenice, Slovakia to promote a better understanding of microphysical properties of aerosol particles, and the characterization of such atmospheric particles using optical techniques. A complementary conference was organized in Nagoya, Japan, the 3rd International Symposium on Atmospheric Light Scattering and Remote Sensing (ISALSaRS), whose goal is to fuse the advances achieved in particle characterization with remote-sensing techniques. While the focus of these meetings is slightly different, they represent the same aspects of this rapidly growing field. This Topical Issue is the first of two parts. Within this issue we analyze different aspects of the problem of atmospheric characterization and present a broad overview of the topical area. Research includes theory and experiment, ranging from fundamental microphysical properties of individual aerosol particles to broad characterizations of atmospheric properties. Since this is an active field, we also have encouraged the submission of ideas for new methodologies that may represent the future of the field.

  15. 78 FR 68502 - Notice of Open Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-14

    ... U.S.-CHINA ECONOMIC AND SECURITY REVIEW COMMISSION Notice of Open Public Meeting AGENCY: U.S.-China Economic and Security Review Commission. ACTION: Notice of Official Public Release of the... recommendations of its 2013 Annual Report to Congress are open to the public. Topics To Be Discussed The...

  16. Life and Biomedical Sciences and Applications Advisory Subcommittee Meeting

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The proceedings of the August 1995 meeting of the Life and Biomedical Sciences and Applications Advisory Subcommittee (LBSAAS) are summarized. The following topics were addressed by the Subcommittee members: the activities and status of the LBSA Division; program activities of the Office of Life and Microgravity Sciences and Applications (OLMSA); the medical Countermeasures Program; and the Fettman Report on animal research activities at ARC. Also presented were a history and overview of the activities of the Space Station Utilization Advisory Committee and the Advanced Life Support Program (ALSP). The meeting agenda and a list of the Subcommittee members and meeting attendees are included as appendices.

  17. Genomics of Extinct and Endangered Species (2011 JGI User Meeting)

    ScienceCinema

    Shuster, Stephen

    2018-02-13

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Stephen Shuster of Penn State University gives a presentation on "Genomics of Extinct and Endangered Species" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011.

  18. 75 FR 70918 - SFIREG Full Committee; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... Association of American Pesticide Control Officials (AAPCO)/State FIFRA Issues Research and Evaluation Group... topics. DATES: The meeting will be held on Monday, December 6, 2010, from 8:30 a.m. to 5 p.m. and Tuesday...

  19. Incorporating Topic Assignment Constraint and Topic Correlation Limitation into Clinical Goal Discovering for Clinical Pathway Mining.

    PubMed

    Xu, Xiao; Jin, Tao; Wei, Zhijie; Wang, Jianmin

    2017-01-01

    Clinical pathways are widely used around the world for providing quality medical treatment and controlling healthcare cost. However, the expert-designed clinical pathways can hardly deal with the variances among hospitals and patients. It calls for more dynamic and adaptive process, which is derived from various clinical data. Topic-based clinical pathway mining is an effective approach to discover a concise process model. Through this approach, the latent topics found by latent Dirichlet allocation (LDA) represent the clinical goals. And process mining methods are used to extract the temporal relations between these topics. However, the topic quality is usually not desirable due to the low performance of the LDA in clinical data. In this paper, we incorporate topic assignment constraint and topic correlation limitation into the LDA to enhance the ability of discovering high-quality topics. Two real-world datasets are used to evaluate the proposed method. The results show that the topics discovered by our method are with higher coherence, informativeness, and coverage than the original LDA. These quality topics are suitable to represent the clinical goals. Also, we illustrate that our method is effective in generating a comprehensive topic-based clinical pathway model.

  20. Incorporating Topic Assignment Constraint and Topic Correlation Limitation into Clinical Goal Discovering for Clinical Pathway Mining

    PubMed Central

    Xu, Xiao; Wei, Zhijie

    2017-01-01

    Clinical pathways are widely used around the world for providing quality medical treatment and controlling healthcare cost. However, the expert-designed clinical pathways can hardly deal with the variances among hospitals and patients. It calls for more dynamic and adaptive process, which is derived from various clinical data. Topic-based clinical pathway mining is an effective approach to discover a concise process model. Through this approach, the latent topics found by latent Dirichlet allocation (LDA) represent the clinical goals. And process mining methods are used to extract the temporal relations between these topics. However, the topic quality is usually not desirable due to the low performance of the LDA in clinical data. In this paper, we incorporate topic assignment constraint and topic correlation limitation into the LDA to enhance the ability of discovering high-quality topics. Two real-world datasets are used to evaluate the proposed method. The results show that the topics discovered by our method are with higher coherence, informativeness, and coverage than the original LDA. These quality topics are suitable to represent the clinical goals. Also, we illustrate that our method is effective in generating a comprehensive topic-based clinical pathway model. PMID:29065617

  1. Coordinating Council. Sixth Meeting: Who Are Our Key Users?

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This NASA Scientific and Technical Information Program Coordinating Council meeting deals with the topic 'Who are our key users?' Presentations were made on the following subtopics: Key users: Who uses the system the most, Who orders the most documents, Users: What do we know about them?, NASA/DOD Aerospace Knowledge Diffusion research project on 'Potential key users', How we meet the user's needs, and STI Council user requirements update. Summaries of discussions after the presentations are included along with visuals for the presentations.

  2. 75 FR 43533 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-26

    ... and off-label use of bone morphogenetic proteins (BMPs). This meeting is open to the public in... use of bone morphogenetic proteins. Background information about this topic, including panel materials... appropriate organizations with expertise in the use of bone morphogenetic protein. II. Meeting Format This...

  3. 75 FR 54385 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-07

    ...The National Geospatial Advisory Committee (NGAC) will meet on September 22-23, 2010 at the American Institute of Architects Building, 1735 New York Avenue, NW., Washington, DC 20006. The meeting will be held in the Gallery Room. The NGAC, which is composed of representatives from governmental, private sector, non-profit, and academic organizations, was established to advise the Chair of the Federal Geographic Data Committee on management of Federal geospatial programs, the development of the National Spatial Data Infrastructure, and the implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include:

  4. 76 FR 55939 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ...The National Geospatial Advisory Committee (NGAC) will meet on October 4-5, 2011 at the National Conservation Training Center, 698 Conservation Way, Shepherdstown, WV 25443. The meeting will be held in Room 201 Instructional East. The NGAC, which is composed of representatives from governmental, private sector, non-profit, and academic organizations, has been established to advise the Chair of the Federal Geographic Data Committee on management of Federal geospatial programs, the development of the National Spatial Data Infrastructure, and the implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include:

  5. 78 FR 16527 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ...The National Geospatial Advisory Committee (NGAC) will meet on April 3, 2013, from 1:00 p.m. to 5:00 p.m. EST. The meeting will be held via Web conference and teleconference. The NGAC, which is composed of representatives from governmental, private sector, non-profit, and academic organizations, has been established to advise the Chair of the Federal Geographic Data Committee on management of Federal geospatial programs, the development of the National Spatial Data Infrastructure, and the implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include:

  6. 78 FR 71638 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ...The National Geospatial Advisory Committee (NGAC) will meet on December 11, 2013, from 1:00 p.m. to 5:00 p.m. EST. The meeting will be held via web conference and teleconference. The NGAC, which is composed of representatives from governmental, private sector, non-profit, and academic organizations, has been established to advise the Chair of the Federal Geographic Data Committee on management of Federal geospatial programs, the development of the National Spatial Data Infrastructure, and the implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include:

  7. 76 FR 10914 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ...The National Geospatial Advisory Committee (NGAC) will meet on March 17-18, 2011 at the American Institute of Architects Building, 1735 New York Avenue, NW., Washington, DC 20006. The meeting will be held in the Gallery Room. The NGAC, which is composed of representatives from governmental, private sector, non-profit, and academic organizations, was established to advise the Federal Geographic Data Committee on management of Federal geospatial programs, the development of the National Spatial Data Infrastructure, and the implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include:

  8. 76 FR 28449 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ...The National Geospatial Advisory Committee (NGAC) will meet on June 8-9, 2011 at the American Institute of Architects Building, 1735 New York Avenue, NW., Washington, DC 20006. The meeting will be held in the Gallery Room. The NGAC, which is composed of representatives from governmental, private sector, non-profit, and academic organizations, was established to advise the Federal Geographic Data Committee on management of Federal geospatial programs, the development of the National Spatial Data Infrastructure, and the implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include:

  9. 75 FR 30855 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ...The National Geospatial Advisory Committee (NGAC) will meet on June 22-23, 2010 at the National Conservation Training Center, 698 Conservation Way, Shepherdstown, WV 25443. The meeting will be held in Room 201 Instructional East. The NGAC, which is composed of representatives from governmental, private sector, non-profit, and academic organizations, has been established to advise the Chair of the Federal Geographic Data Committee on management of Federal geospatial programs, the development of the National Spatial Data Infrastructure, and the implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include:

  10. 75 FR 71141 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-22

    ...The National Geospatial Advisory Committee (NGAC) will meet on December 7-8, 2010 at the American Institute of Architects Building, 1735 New York Avenue, NW., Washington, DC 20006. The meeting will be held in the Gallery Room. The NGAC, which is composed of representatives from governmental, private sector, non-profit, and academic organizations, was established to advise the Federal Geographic Data Committee on management of Federal geospatial programs, the development of the National Spatial Data Infrastructure, and the implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include:

  11. The 7th Asia-Pacific Transport Working Group (APTWG) meeting

    NASA Astrophysics Data System (ADS)

    Ida, K.; Kong, D. F.; Fujita, T.; Ido, T.; Ko, W. H.; Maeyama, S.

    2018-01-01

    This conference report summarizes the contributions to, and discussions at, the 7th Asia-Pacific Transport Working Group Meeting held at Nagoya University, Japan, during 5-8 June 2017. The topics of the meeting were organized under four main headings: (1) turbulence and blob at the boundary of magnetic topology, (2) model reduction and experiments for validation, (3) mode competition in turbulence and MHD driven by energetic particle, (4) mechanism determining plasma flows and their impact on transport and MHD. The Young Researchers Forum which was held in this meeting is also described in this report.

  12. Meeting Report From the Prostate Cancer Foundation Scientific Working Group on Radium-223.

    PubMed

    Miyahira, Andrea K; Morris, Michael; Soule, Howard R

    2017-02-01

    The Prostate Cancer Foundation (PCF) convened a Scientific Working Group Meeting on Radium-223 on September 8, 2016, at The Sidney Kimmel Center for Prostate and Urologic Cancers, Memorial Sloan Kettering Cancer Center. The meeting was attended by 18 investigators with expertise in radium-223, bone biology, molecular imaging, biomarkers, and prostate cancer clinical trials. The goal of this meeting was to discuss the known and unknown surroundings the therapeutic effects of the bone targeting agent radium-223, in bone metastatic prostate cancer therapy, and to outline the most critical studies needed to improve the clinical use of this agent. Three major topic areas were discussed: (1) the basic science of radium; (2) immuno-adjuvant properties of radium therapy; and (3) high impact clinical trials and correlative science. This article reviews the major topics discussed at the meeting for the purpose of accelerating studies that will improve the use of radium-223 in the treatment of prostate cancer patients. Prostate 77:245-254, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  13. The topical treatment of psoriasis.

    PubMed

    van de Kerkhof, P C M; Vissers, W H P M

    2003-01-01

    According to the patients, improvement of efficacy, long-term safety and improvement of compliance are needed. The topical treatment has been innovated during the last decade. Most important are the introduction of two new classes of treatments: topical vitamin D(3) analogues and the retinoid tazarotene. To what extent, however, have we achieved developments which are in line with the needs as expressed by the patients? Improved efficacy has been realized by successful combinations of topical treatments. In particular, the combinations of dithranol, vitamin D(3) and tazarotene with a topical corticosteroid proved to be very effective with a reduced profile of side-effects. The efficacy of vitamin D(3) analogues and tazarotene is such that the efficacy of a potent corticosteroid (betamethasone-17-valerate) is approached; calcipotriol even showed an efficacy which is at least as good as this corticosteroid. The long-term safety of new compounds has been evaluated for at least 12 months in large studies. Remarkably for corticosteroids such information is available for only 12 weeks. However, intermittent applications of a topical corticosteroid in combination with another topical treatment provide an effective and safe long-term control of psoriasis. Compliance is a conditio sine qua non for an effective topical treatment. Important progress has been made to increase compliance. Short-contact dithranol has been popularized as an ambulatory treatment which is a highly effective approach as a care instruction programme. Formulations which are better from a cosmetical point of view have been developed for various topical treatments. Reduction of the frequency of applications proved to be possible for most treatments. Once daily applications for corticosteroids, vitamin D(3) analogues and retinoids have been developed, and intermittent applications, a few times per week, are possible for corticosteroids, which proved to be very effective with a reduced profile of side

  14. Fate of abstracts presented at the 2002 IFCC meeting.

    PubMed

    Uysal, Sezer; Tuglu, Birsen; Ozalp, Ylmaz; Onvural, Banu

    2008-01-01

    Poster presentations at major meetings serve to rapidly present and share study results with the scientific community. On the other hand, full-text publication of abstracts in peer-reviewed journals provides dissemination of knowledge. The purpose of this study was to evaluate the publication rate of abstracts presented at the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Meeting, to assess the factors influencing publication and determine the impact factor of these journals. All poster abstracts presented at the 2002 IFCC Meeting were included in the study. A Medline search was performed to identify a matching journal article. Topics, country of origin, study type, study center and publication year were tabulated. Journals and impact factors of publication were noted. Out of 900 presented abstracts, 125 (13.9%) were published as full-text articles. Publication rates according to topics of the meeting, country of origin and university affiliation demonstrated significant differences. Abstracts from multi-centered studies had higher publication rates, and the journals they were published in had higher impact factors than single center studies. The median impact factor of the journals was 2.093. According to regression analysis, the major predictors for publication were interventional research and university affiliation (odds ratios 2.916 and 1.782, respectively; p < 0.05). The publication rate for abstracts of this clinical chemistry meeting was lower than rates from other fields of medicine. Factors leading to failure require elucidation. Encouraging authors to submit their presentations for full-text publication might improve the rate of publication.

  15. PREFACE: Brazil MRS Meeting 2014

    NASA Astrophysics Data System (ADS)

    2015-11-01

    The annual meetings, organized by the Brazilian materials research society - B-MRS, are amongst the most import discussion forums in the area of materials science and engineering in Brazil, with a growing interest from the national and international scientific society. In the last 4 years, more than 1,500 participants have attended the B-MRS meetings, promoting an auspicious environment for presentation and discussion of scientific and technological works in the materials science area. The XIII Brazilian Materials Research Society Meeting was held from 28 September to 02 October, 2014, in João Pessoa, PB, Brazil. The Meeting congregated more than 1650 participants from the whole of Brazil and from 28 other countries. More than 2100 abstracts were accepted for presentation, distributed along 19 Symposia following the format used in traditional meetings of Materials Research Societies. These involved topics such as: synthesis of new materials, computer simulations, optical, magnetic and electronic properties, traditional materials as clays and cements, advanced metals, carbon and graphene nanostructures, nanomaterials for nanostructures, energy storage systems, composites, surface engineering and others. A novelty was a symposium dedicated to innovation and technology transfer in materials research. The program also included 7 Plenary Lectures presented by internationally renowned researchers: Alberto Salleo from Stanford University, United States of America; Roberto Dovesi from Universita' degli Studi di Torino, Italy; Luís Antonio F. M. Dias Carlos from Universidade de Aveiro, Portugal; Jean Marie Dubois from Institut Jean-Lamour, France; Sir Colin Humphreys from University of Cambridge, England; Karl Leo from Technische Universität Dresden, Germany; Robert Chang from Northwestern University, Evanston, United States of America. The numbers of participants in the B-MRS meetings have been growing continuously, and in this meeting we had almost 2200 presentations

  16. 77 FR 76055 - Office of the Director, National Institutes of Health; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... the Contact Person listed below in advance of the meeting. Name of Committee: Scientific Management... Committee Act, as amended (5 U.S.C. App.), notice is hereby given of a meeting hosted by the NIH Scientific Management Review Board (SMRB). Presentations and discussions will address topics that have been charged to...

  17. Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

    PubMed

    Walsh, Ryan R; Krismer, Florian; Galpern, Wendy R; Wenning, Gregor K; Low, Phillip A; Halliday, Glenda; Koroshetz, Walter J; Holton, Janice; Quinn, Niall P; Rascol, Olivier; Shaw, Leslie M; Eidelberg, David; Bower, Pam; Cummings, Jeffrey L; Abler, Victor; Biedenharn, Judy; Bitan, Gal; Brooks, David J; Brundin, Patrik; Fernandez, Hubert; Fortier, Philip; Freeman, Roy; Gasser, Thomas; Hewitt, Art; Höglinger, Günter U; Huentelman, Matt J; Jensen, Poul H; Jeromin, Andreas; Kang, Un Jung; Kaufmann, Horacio; Kellerman, Lawrence; Khurana, Vikram; Klockgether, Thomas; Kim, Woojin Scott; Langer, Carol; LeWitt, Peter; Masliah, Eliezer; Meissner, Wassilios; Melki, Ronald; Ostrowitzki, Susanne; Piantadosi, Steven; Poewe, Werner; Robertson, David; Roemer, Cyndi; Schenk, Dale; Schlossmacher, Michael; Schmahmann, Jeremy D; Seppi, Klaus; Shih, Lily; Siderowf, Andrew; Stebbins, Glenn T; Stefanova, Nadia; Tsuji, Shoji; Sutton, Sharon; Zhang, Jing

    2018-01-09

    Multiple system atrophy (MSA) is a rare neurodegenerative disorder with substantial knowledge gaps despite recent gains in basic and clinical research. In order to make further advances, concerted international collaboration is vital. In 2014, an international meeting involving leaders in the field and MSA advocacy groups was convened in Las Vegas, Nevada, to identify critical research areas where consensus and progress was needed to improve understanding, diagnosis, and treatment of the disease. Eight topic areas were defined: pathogenesis, preclinical modeling, target identification, endophenotyping, clinical measures, imaging biomarkers, nonimaging biomarkers, treatments/trial designs, and patient advocacy. For each topic area, an expert served as a working group chair and each working group developed priority-ranked research recommendations with associated timelines and pathways to reach the intended goals. In this report, each groups' recommendations are provided. Copyright © 2017 American Academy of Neurology.

  18. NASA STI Program Coordinating Council Twelfth Meeting: Standards

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The theme of this NASA Scientific and Technical Information Program Coordinating Council Meeting was standards and their formation and application. Topics covered included scientific and technical information architecture, the Open Systems Interconnection Transmission Control Protocol/Internet Protocol, Machine-Readable Cataloging (MARC) open system environment procurement, and the Government Information Locator Service.

  19. Abstracts of Presentations--Seventh Annual 4S Meeting.

    ERIC Educational Resources Information Center

    4S - Society for Social Studies of Science, 1982

    1982-01-01

    Presents abstracts of papers for the Seventh Annual Meeting of the Society for the Social Studies of Science. Topics include, among others, rhetoric of a scientific controversy; recombinant DNA; science and social justice; patent citation analysis; national need and peer-review process; and scientism, romanticism, and social realist images of…

  20. Topical treatment of psoriasis: questionnaire results on topical therapy accessibility and influence of body surface area on usage.

    PubMed

    Iversen, L; Lange, M M; Bissonette, R; Carvalho, A V E; van de Kerkhof, P C; Kirby, B; Kleyn, C E; Lynde, C W; van der Walt, J M; Wu, J J

    2017-07-01

    Topical treatment of mild to moderate psoriasis is first-line treatment and exhibits varying degrees of success across patient groups. Key factors influencing treatment success are physician topical treatment choice (high efficacy, low adverse events) and strict patient adherence. Currently, no formalized, international consensus guidelines exist to direct optimal topical treatment, although many countries have national guidelines. To describe and analyse cross-regional variations in the use and access of psoriasis topical therapies. The study was conducted as an observational cross-sectional study. A survey was distributed to dermatologists from the International Psoriasis Council (IPC) to assess topical therapy accessibility in 26 countries and to understand how body surface area (BSA) categories guide clinical decisions on topical use. Variation in the availability of tars, topical retinoids, dithranol and balneotherapy was reported. The vast majority of respondents (100% and 88.4%) used topical therapy as first-line monotherapy in situations with BSA < 3% and BSA between 3% and 10%, respectively. However, with disease severity increasing to BSA > 10%, the number of respondents who prescribe topical therapy decreased considerably. In addition, combination therapy of a topical drug and a systemic drug was frequently reported when BSA measured >10%. This physician survey provides new evidence on topical access and the influence of disease severity on topical usage in an effort to improve treatment strategies on a global level. © 2017 European Academy of Dermatology and Venereology.

  1. Mechanisms of topical analgesics in relieving pain in an animal model of muscular inflammation.

    PubMed

    Duan, Wan-Ru; Lu, Jie; Xie, Yi-Kuan

    2013-09-01

    To investigate the possible mechanisms of topical analgesics in relieving pain in an animal model of muscular inflammation. Adult Sprague-Dawley rats of both sexes were injected with complete Freund's adjuvant to induce inflammation in the anterior tibialis muscle of left hindlimb. One of two types of topical analgesics: Xiaotong Tiegao (XTT), a Tibetan herb compound, or Capzasin (CAP), a cream containing 0.1% capsaicin, was applied to the skin over the inflamed anterior tibialis muscle. The following experiments were performed: pain behavioral tests, evaluation of plasma extravasation in the affected limb, and electrophysiological recordings of afferent nerve fibers. The behavioral experiments demonstrated that applications of either type of topical analgesic to the skin over the inflamed muscle significantly reduced muscular inflammatory pain, as indicated by the increased weight bearing capacity on the affected hindlimb (with latencies of 10 minutes for XTT and 1-2 hours for CAP). Meanwhile, both analgesics caused plasma extravasation in the affected skin. Electrophysiological recordings from the afferent fibers in the related cutaneous nerve indicated that topical analgesics selectively activated C-fibers, but not A-fibers innervating the same region of receptive field. The latency and duration of C-fiber activation was similar to those of the reduction of muscular inflammatory pain. On the contrary, topical analgesics substantially decreased C-fiber afferent spontaneous firing in the nerve innervating the inflamed muscle. Moreover, denervation of the affected skin blocked the analgesic effects of both topical analgesics in muscular inflammatory pain. This study suggests that topical analgesics may reduce the nociceptive input from inflamed muscles via a reflex mechanism by activating the cutaneous nociceptive afferents. Wiley Periodicals, Inc.

  2. A study of an ethics education topic for undergraduate nursing students.

    PubMed

    Kalaitzidis, Evdokia; Schmitz, Karl

    2012-01-01

    The study aims to explore nursing students' perceptions of the relative value of various aspects of the ethical component of the undergraduate topic, 'Ethics and Law applied to Nursing' (topic NURS2104). To enable time for reflection on ethics in nursing, sampling occurred 1 year after successful completion of the above-mentioned topic and after successful completion of all but the final clinical experience components of the Bachelor of Nursing (BN) degree. A significant proportion of respondents perceived ethics education as relevant to professional practices. It is also noteworthy that the ethical decision-making strategies that had been incorporated into the topic (NURS2104) became transformed by the clinical experience of each particular student. While results of this study are not conclusive, they nevertheless provide important information for future nursing students on the evolutionary development of ethics education. Copyright © 2011 Elsevier Ltd. All rights reserved.

  3. Symbiosis: Rich, Exciting, Neglected Topic

    ERIC Educational Resources Information Center

    Rowland, Jane Thomas

    1974-01-01

    Argues that the topic of symbiosis has been greatly neglected and underemphasized in general-biology textbooks. Discusses many types and examples of symbiosis, and provides an extensive bibliography of the literature related to this topic. (JR)

  4. 78 FR 1881 - Notice of Public Meeting; Wyoming Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... Wyoming. Planned agenda topics include a tour of the Rock Springs Wild Horse Holding Facility, a... the Wild Horse Holding Facility on Lionkol Road. Following the tour, the group will meet at the High...

  5. 76 FR 59183 - Meeting of the Regional Resource Stewardship Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... (RRSC) will hold a meeting on October 13 and October 14, 2011, to obtain views and advice on the topic... and Advice. The RRSC will hear opinions and views of citizens by providing a public comment session.... [[Page 59184

  6. Topic Congruence and Topic Interest: How Do They Affect Second Language Reading Comprehension?

    ERIC Educational Resources Information Center

    Lee, Sang-Ki

    2009-01-01

    Because human memory is largely reconstructive, people tend to reorganize and reevaluate an event in a way that is coherent to the truth values held in their belief system. This study investigated the role of topic congruence (defined as whether the reading content corresponds with readers' prior beliefs towards a contentious topic) in second…

  7. Meeting report for mobile DNA 2010.

    PubMed

    Chaconas, George; Craig, Nancy; Curcio, M Joan; Deininger, Prescott; Feschotte, Cedric; Levin, Henry; Rice, Phoebe A; Voytas, Daniel F

    2010-08-24

    An international conference on mobile DNA was held 24-28 April 2010 in Montreal, Canada. Sponsored by the American Society for Microbiology, the conference's goal was to bring together researchers from around the world who study transposition in diverse organisms using multiple experimental approaches. The meeting drew over 190 attendees and most contributed through poster presentations, invited talks and short talks selected from poster abstracts. The talks were organized into eight scientific sessions, which ranged in topic from the evolutionary dynamics of mobile genetic elements to transposition reaction mechanisms. Here we present highlights from the platform sessions with a focus on talks presented by the invited speakers.

  8. Strategies for Finding and Selecting an Ideal Thesis or Dissertation Topic: A Review of Literature

    ERIC Educational Resources Information Center

    Lei, Simon A.

    2009-01-01

    Choosing an ideal master's thesis or doctoral dissertation topic is probably one of the most important decisions students will make while in graduate school. Some graduate students may spend a year or even longer looking for potential topics before finally selecting one for their thesis or dissertation. There are a number of successful strategies…

  9. Proceedings of the Second Switch Tube Advanced Technology Meeting

    NASA Astrophysics Data System (ADS)

    Beavis, L. C.

    1991-07-01

    The Second Switch Tube Technology Review Meeting was held at EG&G Salem, MA, on February 21, 1991. This document is a compilation of the abstracts, viewgraphs and written materials supplied by the presenters from Allied Signal Kansas City Division, EG&G Salem and Sandia National Laboratories. It has not been reviewed nor edited in any way. Also included is an agenda of the meeting and a list of attendees. Covered topics include, Temperature of Uniformity Survey, Brazing Furnace Atmosphere Purity Studies, Creep of Cu Braze Materials and Area Seal Braze Joints, Characterization of the Screen Printing Process, Purity and Structures, Grain Growth and Thermal Treatment of KOVAR, Laser Weldability Testing of KOVAR, Decarburization -- Is It Required, Gross Impurities in KOVAR, Carbon Doping Desorption Studies Update, and MC3857 Sprytron Carbon Doping Matrix Evaluation.

  10. Topical tranexamic acid as an adjuvant treatment in melasma: Side-by-side comparison clinical study.

    PubMed

    Chung, Jong Yoon; Lee, Jong Hee; Lee, Joo Heung

    2016-08-01

    Tranexamic acid (TNA) is a novel therapeutic agent for hyperpigmented skin disorders. The efficacy and safety of topical TNA in patients with melasma has not been heretofore studied. The main objective of this study is to evaluate the efficacy and safety of topical TNA combined with intense pulsed light (IPL) treatment in Asians with melasma. A randomized, split-face (internally controlled) study was conducted in 15 women who received four monthly sessions of IPL to both sides of the face. Topical TNA or vehicle was applied to a randomly assigned side during and after IPL treatment. Patients were followed up for 12 weeks after completing the IPL treatments. Baseline and follow-up melanin index (MI; measured by Mexameter®, Courage and Khazaka, Cologne, Germany) and modified melasma area and severity index (mMASI) scores were determined. Thirteen subjects completed the study without serious adverse events. MI and mMASI decreased significantly from baseline to 12 weeks after the last IPL treatment on the topical TNA side but not on the vehicle side. The efficacy of topical TNA in preventing rebound pigmentation after IPL treatment was also statistically significant. Topical TNA can be considered an effective and safe adjuvant to conventional treatment for melasma.

  11. Differential Topic Models.

    PubMed

    Chen, Changyou; Buntine, Wray; Ding, Nan; Xie, Lexing; Du, Lan

    2015-02-01

    In applications we may want to compare different document collections: they could have shared content but also different and unique aspects in particular collections. This task has been called comparative text mining or cross-collection modeling. We present a differential topic model for this application that models both topic differences and similarities. For this we use hierarchical Bayesian nonparametric models. Moreover, we found it was important to properly model power-law phenomena in topic-word distributions and thus we used the full Pitman-Yor process rather than just a Dirichlet process. Furthermore, we propose the transformed Pitman-Yor process (TPYP) to incorporate prior knowledge such as vocabulary variations in different collections into the model. To deal with the non-conjugate issue between model prior and likelihood in the TPYP, we thus propose an efficient sampling algorithm using a data augmentation technique based on the multinomial theorem. Experimental results show the model discovers interesting aspects of different collections. We also show the proposed MCMC based algorithm achieves a dramatically reduced test perplexity compared to some existing topic models. Finally, we show our model outperforms the state-of-the-art for document classification/ideology prediction on a number of text collections.

  12. No-anesthesia clear corneal phacoemulsification versus topical and topical plus intracameral anesthesia. Randomized clinical trial.

    PubMed

    Pandey, S K; Werner, L; Apple, D J; Agarwal, A; Agarwal, A; Agarwal, S

    2001-10-01

    To compare the intraoperative pain scores during clear corneal phacoemulsification under no anesthesia, topical anesthesia, and topical plus intracameral anesthesia. Dr. Agarwal's Eye Hospital and Eye Research Center, Chennai, India. Seventy-five patients were randomized to have phacoemulsification under no anesthesia, topical anesthesia, or topical plus intracameral anesthesia. Uncooperative or illiterate patients and those with hard cataract, a shallow anterior chamber, or small pupils were excluded. A protocol was established for supplemental anesthesia in case of breakthrough pain during the surgery. Each patient was asked to grade the overall severity of intraoperative pain immediately after surgery on a 10-point visual analog scale. Also evaluated were the general discomfort during surgery, discomfort from the microscope lights, surgeon stress during surgery, and total surgical time. Comparison among the 3 groups was performed using an analysis of variance. No supplemental anesthesia was required in any group. No significant difference was noted in the mean scores of the subjective sensation of pain with or without topical anesthesia (P =.610). The mean scores of patient discomfort from the microscope lights and surgical time were also statistically insignificant. Patient discomfort and surgeon stress during surgery were significantly greater in the no-anesthesia group than in the topical and topical plus intracameral groups (P =.0235 and P = 0.0206, respectively). No-anesthesia clear corneal phacoemulsification was performed by a highly experienced, skilled surgeon without causing an unacceptable level of pain. However, this technique is not suitable for every cataract surgeon or patient.

  13. Genomics of Extinct and Endangered Species (2011 JGI User Meeting)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shuster, Stephen

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Stephen Shuster of Penn State University gives a presentation on "Genomics of Extinct and Endangeredmore » Species" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011.« less

  14. Genomic Speciation and Adaptation in Aquilegia (2011 JGI User Meeting)

    ScienceCinema

    Hodges, Scott

    2018-02-14

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Scott Hodges of the University of California, Santa Barbara gives a presentation on Genomic Speciation and Adaptation in Aquilegia at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011.

  15. JANNAF 18th Propulsion Systems Hazards Subcommittee Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Cocchiaro, James E. (Editor); Gannaway, Mary T. (Editor)

    1999-01-01

    This volume, the first of two volumes is a compilation of 18 unclassified/unlimited-distribution technical papers presented at the Joint Army-Navy-NASA-Air Force (JANNAF) 18th Propulsion Systems Hazards Subcommittee (PSHS) meeting held jointly with the 36th Combustion Subcommittee (CS) and 24th Airbreathing Propulsion Subcommittee (APS) meetings. The meeting was held 18-21 October 1999 at NASA Kennedy Space Center and The DoubleTree Oceanfront Hotel, Cocoa Beach, Florida. Topics covered at the PSHS meeting include: shaped charge jet and kinetic energy penetrator impact vulnerability of gun propellants; thermal decomposition and cookoff behavior of energetic materials; violent reaction; detonation phenomena of solid energetic materials subjected to shock and impact stimuli; and hazard classification, insensitive munitions, and propulsion systems safety.

  16. 10 CFR 7.15 - Procedures for closing an NRC advisory committee meeting.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Procedures for closing an NRC advisory committee meeting. 7.15 Section 7.15 Energy NUCLEAR REGULATORY COMMISSION ADVISORY COMMITTEES § 7.15 Procedures for closing an NRC advisory committee meeting. (a) To close all or part of a meeting of an NRC advisory...

  17. 10 CFR 7.15 - Procedures for closing an NRC advisory committee meeting.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Procedures for closing an NRC advisory committee meeting. 7.15 Section 7.15 Energy NUCLEAR REGULATORY COMMISSION ADVISORY COMMITTEES § 7.15 Procedures for closing an NRC advisory committee meeting. (a) To close all or part of a meeting of an NRC advisory...

  18. 10 CFR 7.15 - Procedures for closing an NRC advisory committee meeting.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Procedures for closing an NRC advisory committee meeting. 7.15 Section 7.15 Energy NUCLEAR REGULATORY COMMISSION ADVISORY COMMITTEES § 7.15 Procedures for closing an NRC advisory committee meeting. (a) To close all or part of a meeting of an NRC advisory...

  19. 10 CFR 7.15 - Procedures for closing an NRC advisory committee meeting.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Procedures for closing an NRC advisory committee meeting. 7.15 Section 7.15 Energy NUCLEAR REGULATORY COMMISSION ADVISORY COMMITTEES § 7.15 Procedures for closing an NRC advisory committee meeting. (a) To close all or part of a meeting of an NRC advisory...

  20. 10 CFR 7.15 - Procedures for closing an NRC advisory committee meeting.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Procedures for closing an NRC advisory committee meeting. 7.15 Section 7.15 Energy NUCLEAR REGULATORY COMMISSION ADVISORY COMMITTEES § 7.15 Procedures for closing an NRC advisory committee meeting. (a) To close all or part of a meeting of an NRC advisory...

  1. 75 FR 7452 - Notice of Partially Closed Meeting of the Chief of Naval Operations (CNO) Executive Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... topics to be presented during the closed portion of the meeting are classified SECRET and SECRET//NOFORN... be kept secret in the interest of national defense. In addition, matters determined to be business sensitive (trade secrets and privileged commercial and financial information) are exempt from an open...

  2. FNLAC Meeting Showcases Frederick National Laboratory’s Achievements, Future Plans | Poster

    Cancer.gov

    Recent accomplishments and upcoming initiatives at the Frederick National Laboratory (FNL) were the hottest topics at the recent Frederick National Laboratory Advisory Committee (FNLAC) meeting. Here are some excerpts, accompanied by time stamps from the videocast.

  3. Tailoring periodical collections to meet institutional needs.

    PubMed Central

    Delman, B S

    1984-01-01

    A system for tailoring journal collections to meet institutional needs is described. The approach is based on the view that reference work and collection development are variant and complementary forms of the same library function; both tasks have as their objective a literature response to information problems. Utilizing the tools and procedures of the reference search in response to a specific collection development problem topic, the author created a model ranked list of relevant journals. Finally, by linking the model to certain operational and environmental factors in three different health care organizations, he tailored the collection to meet the institutions' respective information needs. PMID:6375775

  4. JANNAF 37th Combustion Subcommittee Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Fry, Ronald S. (Editor); Gannaway, Mary T. (Editor)

    2000-01-01

    This volume, the first of two volumes is a compilation of 59 unclassified/unlimited-distribution technical papers presented at the Joint Army-Navy-NASA-Air Force (JANNAF) 37th Combustion Subcommittee (CS) meeting held jointly with the 25th Airbreathing Propulsion Subcommittee (APS), 19th Propulsion Systems Hazards Subcommittee (PSHS), and 1st Modeling and Simulation Subcommittee (MSS) meetings. The meeting was held 13-17 November 2000 at the Naval Postgraduate School and Hyatt Regency Hotel, Monterey, California. Topics covered at the CS meeting include: a keynote address on the Future Combat Systems, and review of a new JANNAF Modeling and Simulation Subcommittee, and technical papers on gun propellant burning rate, gun tube erosion, advanced gun propulsion concepts, ETC guns, novel gun propellants; liquid, hybrid and novel propellant combustion; solid propellant combustion kinetics, GAP, ADN and RDX combustion, sandwich combustion, metal combustion, combustion instability, and motor combustion instability.

  5. Use of Topical Tacrolimus and Topical Pimecrolimus in Four European Countries: A Multicentre Database Cohort Study.

    PubMed

    Kuiper, Josephina G; van Herk-Sukel, Myrthe P P; Castellsague, Jordi; Pottegård, Anton; Berglind, Ingegärd Anveden; Dedman, Daniel; Gutierrez, Lia; Calingaert, Brian; Hallas, Jesper; Sundström, Anders; Gallagher, Arlene M; Kaye, James A; Pardo, Carolina; Rothman, Kenneth J; Perez-Gutthann, Susana

    2018-05-07

    Despite the concerns about a potential increased risk of skin cancer and lymphoma with the use of topical tacrolimus and pimecrolimus, no population-based studies have given an overview of the use of these drugs in Europe. To assess the use of topical tacrolimus and pimecrolimus in children and adults in Europe. Multicentre database cohort study comprising data from the Netherlands, Denmark, Sweden and the UK. We analysed users of topical tacrolimus and pimecrolimus starting from the date of first availability (between 2002 and 2003) or start establishment of the prescription database in Sweden (2006) through 2011. Use was assessed separately for children (≤ 18 years) and adults. 32,052 children and 104,902 adults were treated with topical tacrolimus, and 32,125 children and 58,280 adults were treated with topical pimecrolimus. The number of users increased rapidly after first availability, especially for topical tacrolimus. Topical tacrolimus was more frequently used in all countries except Denmark. For both drugs, there was a decrease in users after 2004 in the Netherlands and Denmark and after 2005 in the UK, especially among children. This decrease was largest in Denmark. The decrease in the number of users was temporary for topical tacrolimus, while use remained relatively low for topical pimecrolimus. The number of topical tacrolimus and pimecrolimus users increased rapidly after regulatory approval. A transient reduction in topical tacrolimus use and a persistent reduction in topical pimecrolimus use was seen after 2004 in the Netherlands and Denmark and after 2005 in the UK.

  6. Six key topics informal carers of patients with breathlessness in advanced disease want to learn about and why: MRC phase I study to inform an educational intervention.

    PubMed

    Farquhar, Morag; Penfold, Clarissa; Benson, John; Lovick, Roberta; Mahadeva, Ravi; Howson, Sophie; Burkin, Julie; Booth, Sara; Gilligan, David; Todd, Christopher; Ewing, Gail

    2017-01-01

    Breathlessness is a common symptom of advanced disease placing a huge burden on patients, health systems and informal carers (families and friends providing daily help and support). It causes distress and isolation. Carers provide complex personal, practical and emotional support yet often feel ill-prepared to care. They lack knowledge and confidence in their caring role. The need to educate carers and families about breathlessness is established, yet we lack robustly developed carer-targeted educational interventions to meet their needs. We conducted a qualitative interview study with twenty five purposively-sampled patient-carer dyads living with breathlessness in advanced disease (half living with advanced cancer and half with advanced chronic obstructive pulmonary disease (COPD). We sought to identify carers' educational needs (including what they wanted to learn about) and explore differences by diagnostic group in order to inform an educational intervention for carers of patients with breathlessness in advanced disease. There was a strong desire among carers for an educational intervention on breathlessness. Six key topics emerged as salient for them: 1) understanding breathlessness, 2) managing anxiety, panic and breathlessness, 3) managing infections, 4) keeping active, 5) living positively and 6) knowing what to expect in the future. A cross-cutting theme was relationship management: there were tensions within dyads resulting from mismatched expectations related to most topics. Carers felt that knowledge-gains would not only help them to support the patient better, but also help them to manage their own frustrations, anxieties, and quality of life. Different drivers for education need were identified by diagnostic group, possibly related to differences in caring role duration and resulting impacts. Meeting the educational needs of carers requires robustly developed and evaluated interventions. This study provides the evidence-base for the content of an

  7. National Association for Research in Science Teaching. 50th Annual Meeting, Abstracts of Presented Papers.

    ERIC Educational Resources Information Center

    Helgeson, Stanley L., Ed.

    This publication provides abstracts of papers presented at the 50th annual meeting of the National Association for Research in Science Teaching held in Cincinnati, Ohio March 22-24, 1977. The entries represent a wide range of topics in the field of science education. Topics include instruction, teacher education, learning, enrollments, concept…

  8. Geotechnical support and topical studies for nuclear waste geologic repositories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1989-01-01

    The present report lists the technical reviews and comments made during the fiscal year 1988 and summarizes the technical progress of the topical studies. In the area of technical assistance, there were numerous activities detailed in the next section. These included 24 geotechnical support activities, including reviews of 6 Study Plans (SP) and participation in 6 SP Review Workshops, review of one whole document Site Characterization Plan (SCP) and participation in the Assembled Document SCP Review Workshops by 6 LBL reviewers; the hosting of a DOE program review, the rewriting of the project statement of work, 2 trips to technicalmore » and planning meetings; preparation of proposed work statements for two new topics for DOE, and 5 instances of technical assistance to DOE. These activities are described in a Table in the following section entitled Geoscience Technical Support for Nuclear Waste Geologic Repositories.''« less

  9. Proceedings of the 1992 Annual Meeting NASA Occupational Health Program

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The purpose of this meeting was to exchange information across NASA facilities that is critical to agency-wide improvement in the efforts to maintain and enhance employee health. The topics covered include the following: occupational medicine, environmental health, physical fitness, and health education.

  10. Topic Modeling Reveals Distinct Interests within an Online Conspiracy Forum

    PubMed Central

    Klein, Colin; Clutton, Peter; Polito, Vince

    2018-01-01

    Conspiracy theories play a troubling role in political discourse. Online forums provide a valuable window into everyday conspiracy theorizing, and can give a clue to the motivations and interests of those who post in such forums. Yet this online activity can be difficult to quantify and study. We describe a unique approach to studying online conspiracy theorists which used non-negative matrix factorization to create a topic model of authors' contributions to the main conspiracy forum on Reddit.com. This subreddit provides a large corpus of comments which spans many years and numerous authors. We show that within the forum, there are multiple sub-populations distinguishable by their loadings on different topics in the model. Further, we argue, these differences are interpretable as differences in background beliefs and motivations. The diversity of the distinct subgroups places constraints on theories of what generates conspiracy theorizing. We argue that traditional “monological” believers are only the tip of an iceberg of commenters. Neither simple irrationality nor common preoccupations can account for the observed diversity. Instead, we suggest, those who endorse conspiracies seem to be primarily brought together by epistemological concerns, and that these central concerns link an otherwise heterogenous group of individuals. PMID:29515501

  11. EDITORIAL: Special issue containing papers presented at the 11th IAEA Technical Meeting on Energetic Particles in Magnetic Confinement Systems Special issue containing papers presented at the 11th IAEA Technical Meeting on Energetic Particles in Magnetic Confinement Systems

    NASA Astrophysics Data System (ADS)

    Kolesnichenko, Ya.

    2010-08-01

    The history of fusion research resembles the way in which one builds skyscrapers: laying the first foundation stone, one thinks about the top of the skyscraper. At the early stages of fusion, when it became clear that the thermonuclear reactor would operate with DT plasma confined by the magnetic field, the study of the `top item'—the physics of 3.5 MeV alpha particles produced by the DT fusion reaction—was initiated. The first publications on this topic appeared as long ago as the 1960s. At that time, because the physics of alpha particles was far from the experimental demand, investigations were carried out by small groups of theoreticians who hoped to discover important and interesting phenomena in this new research area. Soon after the beginning of the work, theoreticians discovered that alpha particles could excite various instabilities in fusion plasmas. In particular, at the end of the 1960s an Alfvén instability driven by alpha particles was predicted. Later it turned out that a variety of Alfvén instabilities with very different features does exist. Instabilities with perturbations of the Alfvénic type play an important role in current experiments; it is likely that they will affect plasma performance in ITER and future reactors. The first experimental manifestation of instabilities excited by superthermal particles in fusion devices was observed in the PDX tokamak in 1983. In this device a large-scale instability—the so called `fishbone instability'—associated with ions produced by the neutral beam injection resulted in a loss of a large fraction of the injected energy. Since then, the study of energetic-ion-driven instabilities and the effects produced by energetic ions in fusion plasmas has attracted the growing attention of both experimentalists and theorists. Recognizing the importance of this topic, the first conference on fusion alpha particles was held in 1989 in Kyiv under the auspices of the IAEA. The meeting in Kyiv and several

  12. Summary of the discussion meeting on alpha particle theory problems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sigmar, D.J.

    1988-04-01

    The agenda of the meeting (consisting of {approximately}20 theoreticians and 2 experimentalists working on single {alpha}-particle effects and diagnostics) was to discuss the spectrum of relevant {alpha}-theory problems as it is presently understood, its impact on ignited plasma performance, and possible paths to stabilization. The purpose was to expose existing efforts to peer review and to focus on the most important topics. Twenty-one talks were given which are summarized. Overall, there emerged a consensus about the existence of robust (MHD-like) collective oscillations affecting both the {alpha}-species and the bulk plasma. In addition, improved calculations of classical {alpha}-phenomena due to driftmore » orbits and collisions and {alpha}-RF interactions were discussed. An overview of topics covered is given in the attached conference program.« less

  13. My Kind of Town (Chicago Is): Content Collections Optimize Learning Related to the 2018 AANA Annual Meeting.

    PubMed

    Hunt, Timothy J; Brand, Jefferson C; Rossi, Michael J; Lubowitz, James H

    2018-04-01

    The 2018 Arthroscopy Association of North America Annual Meeting represents an opportunity to deepen one's understanding of a wide variety of topics. Arthroscopy journal readers have diverse practices and interests, and the meeting is designed to accommodate individual needs. The constructivist learning theory provides that scholars learn in many different ways. Thus, to enrich your learning experience, selected recently published Arthroscopy articles are suggested to supplement material presented at the meeting. The articles are collated on our web site in Content Collections, to allow meeting participants to prepare and to allow those unable to attend to remain engaged. We offer suggestions and encourage readers to customize their own learning experience. Copyright © 2018 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  14. Topical Treatment of Degenerative Knee Osteoarthritis.

    PubMed

    Meng, Zengdong; Huang, Rongzhong

    2018-01-01

    This article reviews topical management strategies for degenerative osteoarthritis (OA) of the knee. A search of Pubmed, Embase and the Cochrane library using MeSH terms including "topical," "treatment," "knee" and "osteoarthritis" was carried out. Original research and review articles on the effectiveness and safety, recommendations from international published guidelines and acceptability studies of topical preparations were included. Current topical treatments included for the management of knee OA include topical nonsteroidal anti-inflammatory drugs, capsaicin, salicylates and physical treatments such as hot or cold therapy. Current treatment guidelines recommend topical nonsteroidal anti-inflammatory drugs as an alternative and even first-line therapy for OA management, especially among elderly patients. Guidelines on other topical treatments vary, from recommendations against their use, to in favor as alternative or simultaneous therapy, especially for patients with contraindications to other analgesics. Although often well-tolerated and preferred by many patients, clinical care still lags in the adoption of topical treatments. Aspects of efficacy, safety and patient quality of life data require further research. Copyright © 2018 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

  15. Summary Report: 2017 Annual Grantees Meeting of the NIH-EPA Centers of Excellence on Environmental Health Disparities Research

    EPA Science Inventory

    Approximately 100 researchers, trainees, students, and community partners attended the 2-day grantees meeting. In addition to research updates by the five EHD Centers, the meeting featured working group discussions around topics such as research translation, cross-center collabor...

  16. Proceedings [of the] Sixty Seventh Annual Meeting [of the ] National College Physical Education Association for Men.

    ERIC Educational Resources Information Center

    American Alliance for Health, Physical Education, and Recreation, Washington, DC.

    This document contains the proceedings of the January 1964 Annual Meeting of the National College Physical Education Association for Men (NEPEAM). In addition to the President's address and a speech on physical education as an academic discipline, the Proceedings contain speeches on the following topics: (1) intramural athletics, (2) research, (3)…

  17. 78 FR 30328 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... academic organizations, was established to advise the Federal Geographic Data Committee on management of... implementation of Office of Management and Budget (OMB) Circular A- 16. Topics to be addressed at the meeting include: Leadership Dialogue NSDI Strategic Plan Geospatial Platform OMB Circular A-16 Portfolio...

  18. 78 FR 49282 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-13

    ... academic organizations, was established to advise the Federal Geographic Data Committee on management of... implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include: --Leadership Dialogue --Recent FGDC Activities --Geospatial Platform --NSDI Strategic Plan --3D...

  19. 77 FR 52053 - Announcement of National Geospatial Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ... academic organizations, was established to advise the Federal Geographic Data Committee on management of... implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include: Leadership Dialogue Geospatial Platform Geolocation Privacy FGDC Report COGO Report Card...

  20. 75 FR 72834 - Blood Products Advisory Committee; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-26

    ... Pearline Muckelvene, Center for Biologics Evaluation and Research, Food and Drug Administration (HFM- 71... following topics: (1) November 4 and 5, 2010, meeting of the Health and Human Services Advisory Committee on... (3) Research programs in the Laboratories of Hemostasis and Plasma Derivatives, Division of...

  1. The Nordic countries meeting on the zebrafish as a model for development and disease 2012.

    PubMed

    Andersson Lendahl, Monika; Zetterberg, Henrik

    2013-03-01

    The first Nordic Countries Meeting on the Zebrafish as a Model for Development and Disease took place at Karolinska Institutet in Stockholm, November 21-23, 2012. The meeting gathered 130 scientists, students, and company representatives from Iceland, Finland, Norway, Denmark, and Sweden, as well as invited guests and keynote speakers from England, Scotland, Germany, Poland, The Netherlands, Singapore, Japan, and the United States. Presentations covered a wide range of topics, including developmental biology, genetics, evolutionary biology, toxicology, behavioral studies, and disease mechanisms. The need for formal guidance and training in zebrafish housing, husbandry, and health monitoring was recognized, and the meeting expressed its support for the joint working group of the FELASA/COST action BM0804 EuFishBioMed. The decision was made to turn the Nordic meeting into an annual event and create a Nordic network of zebrafish researchers.

  2. Cairo consensus on the IVF laboratory environment and air quality: report of an expert meeting.

    PubMed

    Mortimer, D; Cohen, J; Mortimer, S T; Fawzy, M; McCulloh, D H; Morbeck, D E; Pollet-Villard, X; Mansour, R T; Brison, D R; Doshi, A; Harper, J C; Swain, J E; Gilligan, A V

    2018-03-02

    This proceedings report presents the outcomes from an international Expert Meeting to establish a consensus on the recommended technical and operational requirements for air quality within modern assisted reproduction technology (ART) laboratories. Topics considered included design and construction of the facility, as well as its heating, ventilation and air conditioning system; control of particulates, micro-organisms (bacteria, fungi and viruses) and volatile organic compounds (VOCs) within critical areas; safe cleaning practices; operational practices to optimize air quality while minimizing physicochemical risks to gametes and embryos (temperature control versus air flow); and appropriate infection-control practices that minimize exposure to VOC. More than 50 consensus points were established under the general headings of assessing site suitability, basic design criteria for new construction, and laboratory commissioning and ongoing VOC management. These consensus points should be considered as aspirational benchmarks for existing ART laboratories, and as guidelines for the construction of new ART laboratories. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

  3. The Impact of Sunshine/Open Meeting Laws on the Governing Boards of Public Colleges and Universities.

    ERIC Educational Resources Information Center

    Kaplowitz, Richard A.

    The provisions of "sunshine" or "open meeting" laws are discussed to assist governing boards and chief executive officers of public universities and colleges. These laws stipulate that the business of the public must be conducted in public. Topics include: the legal constitution of a meeting, personnel matters, collective…

  4. JANNAF 19th Propulsion Systems Hazards Subcommittee Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Cocchiaro, James E. (Editor); Kuckels, Melanie C. (Editor)

    2000-01-01

    This volume, the first of two volumes is a compilation of 25 unclassified/unlimited-distribution technical papers presented at the Joint Army-Navy-NASA-Air Force (JANNAF) 19th Propulsion Systems Hazards Subcommittee (PSHS) meeting held jointly with the 37th Combustion Subcommittee (CS) and 25th Airbreathing Propulsion Subcommittee (APS), and 1st Modeling and Simulation Subcommittee (MSS) meetings. The meeting was held 13-17 November 2000 at the Naval Postgraduate School and Hyatt Regency Hotel, Monterey, California. Topics covered at the PSHS meeting include: impact and thermal vulnerability of gun propellants; thermal decomposition and cookoff behavior of energetic materials; violent reaction and detonation phenomena of solid energetic materials subjected to shock and impact loading; and hazard classification, and insensitive munitions testing of propellants and propulsion systems.

  5. An Overview of Tracheal Stenosis Research Trends and Hot Topics.

    PubMed

    Farzanegan, Roya; Feizabadi, Mansoureh; Ghorbani, Fariba; Movassaghi, Masoud; Vaziri, Esmaeil; Zangi, Mahdi; Lajevardi, Seyedamirmohammad; Shadmehr, Mohammad Behgam

    2017-09-01

    Tracheal stenosis remains a challenge in the thoracic surgery field. Recognizing the hot topics and major concepts in this area would help the health policy makers to determine their own priorities and design the effective research plans. The present study analyzed and mapped the topics and trends of tracheal stenosis studies over time as well as authors' and countries' contributions. Search results were obtained employing Bibexcel. To determine cold and hot topics, co-occurrence analysis was applied using three international databases 'Web of Science', 'PubMed' and 'Scopus'. Appropriately, different categories in the articles such as keywords, authors, and countries were explored via VOSviewer and NetDraw. Afterward, the trends of research topics were depicted in four time-intervals from 1945 to 2015 by ten co-occurrence terms. The majority of articles were limited to case series and retrospective studies. The studies had been conducted less frequently on prevention, risk factors and incidence determination but extensively on treatment and procedures. Based on the articles indexed in WOS, 45 countries and 8,260 authors have contributed to scientific progress in this field. The highest degree of cooperation occurred between the USA and England with 15 common papers. Most of the published literature in tracheal stenosis research field was about surgical and non-surgical treatments. Conducting the screening and prevention studies would diminish the burden of this disease on the health system as well as the patients and their families' well-being.

  6. Recent advances in topical anesthesia

    PubMed Central

    2016-01-01

    Topical anesthetics act on the peripheral nerves and reduce the sensation of pain at the site of application. In dentistry, they are used to control local pain caused by needling, placement of orthodontic bands, the vomiting reflex, oral mucositis, and rubber-dam clamp placement. Traditional topical anesthetics contain lidocaine or benzocaine as active ingredients and are used in the form of solutions, creams, gels, and sprays. Eutectic mixtures of local anesthesia cream, a mixture of various topical anesthetics, has been reported to be more potent than other anesthetics. Recently, new products with modified ingredients and application methods have been introduced into the market. These products may be used for mild pain during periodontal treatment, such as scaling. Dentists should be aware that topical anesthetics, although rare, might induce allergic reactions or side effects as a result of an overdose. Topical anesthetics are useful aids during dental treatment, as they reduce dental phobia, especially in children, by mitigating discomfort and pain. PMID:28879311

  7. ZOONET: perspectives on the evolution of animal form. Meeting report.

    PubMed

    Fischer, Antje H L; Arboleda, Enrique; Egger, Bernhard; Hilbrant, Maarten; McGregor, Alistair P; Cole, Alison G; Daley, Allison C

    2009-11-15

    What drives evolution? This was one of the main questions raised at the final ZOONET meeting in Budapest, Hungary, in November 2008. The meeting marked the conclusion of ZOONET, an EU-funded Marie-Curie Research Training Network comprising nine research groups from all over Europe (Max Telford, University College London; Michael Akam, University of Cambridge; Detlev Arendt, EMBL Heidelberg; Maria Ina Arnone, Stazione Zoologica Anton Dohrn Napoli; Michalis Averof, IMBB Heraklion; Graham Budd, Uppsala University; Richard Copley, University of Oxford; Wim Damen, University of Cologne; Ernst Wimmer, University of Göttingen). ZOONET meetings and practical courses held during the past four years provided researchers from diverse backgrounds--bioinformatics, phylogenetics, embryology, palaeontology, and developmental and molecular biology--the opportunity to discuss their work under a common umbrella of evolutionary developmental biology (Evo Devo). The Budapest meeting emphasized in-depth discussions of the key concepts defining Evo Devo, and bringing together ZOONET researchers with external speakers who were invited to present their views on the evolution of animal form. The discussion sessions addressed four main topics: the driving forces of evolution, segmentation, fossils and phylogeny, and the future of Evo Devo.

  8. Freshman Health Topics

    ERIC Educational Resources Information Center

    Hovde, Karen

    2011-01-01

    This article examines a cluster of health topics that are frequently selected by students in lower division classes. Topics address issues relating to addictive substances, including alcohol and tobacco, eating disorders, obesity, and dieting. Analysis of the topics examines their interrelationships and organization in the reference literature.…

  9. A needs assessment of education research topics among surgical educators in the United States.

    PubMed

    Phitayakorn, R; Salles, A; Falcone, J L; Jensen, A R; Steinemann, S; Torbeck, L

    2017-02-01

    There are currently no courses that focus specifically on surgical education research. A needs assessment of surgical educators is required to best design these courses. A cross-sectional survey-based study on all faculty members of the Association for Surgical Education was done to determine their education research needs. The overall response rate was 15% and the majority of the 78 respondents were physicians (63%) in their mid- to late career stage (65%). Participants thought research topics should be taught at an advanced level in a workshop format. Senior educators were less interested than junior educators in learning to create conceptual frameworks (p = 0.038) and presenting their research at national meetings (p = 0.014). Surgical educators desire more training in education research techniques that are taught in a workshop format at a national surgical education meeting. These workshops may lay the groundwork for a nationally recognized certificate in surgical education research. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Topical drug delivery systems: a patent review.

    PubMed

    Singh Malik, Deepinder; Mital, Neeraj; Kaur, Gurpreet

    2016-01-01

    Topical administration is the favored route for local delivery of therapeutic agents due to its convenience and affordability. The specific challenge of designing a therapeutic system is to achieve an optimal concentration of a certain drug at its site of action for an appropriate duration. This review summarizes innovations from the past 3 years (2012-2015) in the field of topical drug delivery for the treatment of local infections of the vagina, nose, eye and skin. The review also throws some light on the anatomy and physiology of these organs and their various defensive barriers which affect the delivery of drugs administered topically. Topical administration has been gaining attention over the last few years. However, conventional topical drug delivery systems suffer from drawbacks such as poor retention and low bioavailability. The successful formulation of topical delivery products requires the careful manipulation of defensive barriers and selection of a soluble drug carrier. Extensive research is required to develop newer topical drug delivery systems aiming either to improve the efficacy or to reduce side effects compared to current patented systems.

  11. Conference on the topic: {open_quotes}Exploration and production of petroleum and gas from chalk reservoirs worldwide{close_quotes}

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kuznetsov, V.G.

    1995-07-01

    More than 170 delegates from 14 countries in Europe, North America, Africa, and Asia took part in a conference on the topic: Exploration and Production of Petroleum and Gas from Chalk Reservoirs Worldwide. The conference was held in Copenhagen, Denmark in September,1994, and was a joint meeting of the American Association of Petroleum Geologists (AAPG), and the European Association of Petroleum Geoscientists and Engineers (EAPG). In addition to the opening remarks, 25 oral and nine poster reports were presented. The topics included chalk deposits as reservoir rocks, the occurrence of chalk deposits worldwide, the North Sea oil and gas fields,more » and other related topics.« less

  12. Panel session on "how to meet the challenges for nuclear power".

    PubMed

    Tenforde, Thomas S

    2011-01-01

    This panel session at the 2009 Annual Meeting involved a discussion of views of government, industry, and national research laboratory members on the primary future goals in developing advanced nuclear reactor and nuclear fuel cycle designs, fuel management, and used fuel disposal options. The session at the 2009 NCRP Annual Meeting on "How to Meet the Challenges for Nuclear Power" was chaired by Mary E. Clark of the U.S. Environmental Protection Agency and focused on efforts in the United States and worldwide to expand nuclear capabilities for electric power production in a safe, secure, and environmentally acceptable manner. This paper briefly summarizes the key topics discussed in five presentations during this session of the NCRP Annual Meeting. Copyright © 2010 Health Physics Society

  13. New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31stAnnual Meeting of the Society for Immunotherapy of Cancer, 2016.

    PubMed

    Adusumilli, Prasad S; Cha, Edward; Cornfeld, Mark; Davis, Thomas; Diab, Adi; Dubensky, Thomas W; Evans, Elizabeth; Grogan, Jane L; Irving, Bryan A; Leidner, Rom S; Olwill, Shane A; Soon-Shiong, Patrick; Triebel, Frederic; Tuck, David; Bot, Adrian; Dansey, Roger D; Drake, Charles G; Freeman, Gordon J; Ibrahim, Ramy; Patel, Salil; Chen, Daniel S

    2017-01-01

    This report is a summary of 'New Cancer Immunotherapy Agents in Development' program, which took place in association with the 31st Annual Meeting of the Society for Immunotherapy of Cancer (SITC), on November 9, 2016 in National Harbor, Maryland. Presenters gave brief overviews of emerging clinical and pre-clinical immune-based agents and combinations, before participating in an extended panel discussion with multidisciplinary leaders, including members of the FDA, leading academic institutions and industrial drug developers, to consider topics relevant to the future of cancer immunotherapy.

  14. Proceedings of the Twelfth NASA Propagation Experimenters Meeting (NAPEX 12)

    NASA Technical Reports Server (NTRS)

    Davarian, Faramaz (Editor)

    1988-01-01

    The NASA Propagation Experimenters Meeting was convened on June 9 and 10, 1988. Pilot Field Experiments propagation studies, mobile communication systems, signal fading, communication satellites rain gauge network measurements, atmospheric attenuation studies, optical communication through the atmosphere, and digital beacon receivers were among the topics discussed.

  15. Deep Unfolding for Topic Models.

    PubMed

    Chien, Jen-Tzung; Lee, Chao-Hsi

    2018-02-01

    Deep unfolding provides an approach to integrate the probabilistic generative models and the deterministic neural networks. Such an approach is benefited by deep representation, easy interpretation, flexible learning and stochastic modeling. This study develops the unsupervised and supervised learning of deep unfolded topic models for document representation and classification. Conventionally, the unsupervised and supervised topic models are inferred via the variational inference algorithm where the model parameters are estimated by maximizing the lower bound of logarithm of marginal likelihood using input documents without and with class labels, respectively. The representation capability or classification accuracy is constrained by the variational lower bound and the tied model parameters across inference procedure. This paper aims to relax these constraints by directly maximizing the end performance criterion and continuously untying the parameters in learning process via deep unfolding inference (DUI). The inference procedure is treated as the layer-wise learning in a deep neural network. The end performance is iteratively improved by using the estimated topic parameters according to the exponentiated updates. Deep learning of topic models is therefore implemented through a back-propagation procedure. Experimental results show the merits of DUI with increasing number of layers compared with variational inference in unsupervised as well as supervised topic models.

  16. 78 FR 64025 - Sunshine Act Meeting Notice; Matter Added to the Agenda for Consideration at an Agency Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... NATIONAL CREDIT UNION ADMINISTRATION Sunshine Act Meeting Notice; Matter Added to the Agenda for Consideration at an Agency Meeting FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT: October 21, 2013 (78 FR... ``Government in Sunshine Act'' notice is hereby given that the NCUA Board gave notice on October 21, 2013 (78...

  17. Proceedings [of the] Sixty Eighth Annual Meeting [of the] National College Physical Education Association for Men.

    ERIC Educational Resources Information Center

    American Alliance for Health, Physical Education, and Recreation, Washington, DC.

    This document contains the proceedings of the January 1965 Annual meeting of the National College Physical Education Association for Men (NCPEAM). In addition to the special addresses given at the meeting, the proceedings contain speeches on the following topics: (1) research, (2) intercollegiate athletics, (3) history of sport, (4) teacher…

  18. 75 FR 2549 - Clinical Accuracy Requirements for Point of Care Blood Glucose Meters; Public Meeting; Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ...] Clinical Accuracy Requirements for Point of Care Blood Glucose Meters; Public Meeting; Request for Comments... Requirements for Point of Care Blood Glucose Meters. The purpose of the public meeting is to discuss the clinical accuracy requirements of blood glucose meters and other topics related to their use in point of...

  19. Consultative meeting considers past successes and future programmes for subregional network.

    PubMed

    1999-01-01

    This article presents the proceedings of the consultative meeting held in Beijing during October 18-19, 1999. Representatives from the population information (POPIN) centers in China, Indonesia, Lao People's Democratic Republic, Malaysia, Mongolia, Myanmar, Philippines, Republic of Korea, Thailand, and Vietnam participated in the meeting. The major objectives were to exchange and share experiences among the network members and to draw up a cooperative work plan for carrying out information activities more effectively in the coming year and beyond. Highlights of the meeting include the presentation of the results of an Asia-Pacific POPIN survey, which evaluated information technology (IT) capabilities among members and evaluation of the 1999 IT-focused training workshop; a review of POPIN activities conducted by the subregional network's members in the past year; and a discussion of major topics for cooperative activities. Moreover, a work plan was formulated for the East and South-East Asia POPIN subregional network for October 1999-October 2000.

  20. Building Communities: The Community Sequencing Program at JGI (2011 JGI User Meeting)

    ScienceCinema

    Bristow, Jim

    2018-01-22

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy Environment Meeting held March 22-24, 2011 in Walnut Creek, CA. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. DOE JGI Deputy Director Jim Bristow gives a presentation on the Community Sequencing Program at the 6th annual Genomics of Energy and Environment Meeting on March 23, 2011.

  1. The Gulf Oil Spill: Ecogenomics and Ecoresilience (Keynote - 2011 JGI User Meeting)

    ScienceCinema

    Hazen, Terry [LBNL

    2018-04-25

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Berkeley Lab microbial ecologist Terry Hazen delivers a keynote on "The Gulf Oil Spill: Ecogenomics and Ecoresilience" at the 6th Genomics of Energy & Environment Meeting on March 22, 2011.

  2. 78 FR 44591 - Notice of Public Meeting; Wyoming Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-24

    ... public land management in Wyoming. Planned agenda topics include discussions on uranium, cultural, NEPA... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLWY910000 L16100000 XX0000] Notice of Public Meeting; Wyoming Resource Advisory Council AGENCY: Bureau of Land Management, Interior. ACTION...

  3. 19th JANNAF Safety and Environmental Protection Subcommittee Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Cocchiaro, J. E. (Editor); Becker, D. L. (Editor)

    2002-01-01

    This volume, the first of two volumes, is a compilation of 22 unclassified/unlimited technical papers presented at the 19th Joint Army-Navy-NASA-Air Force (JANNAF) Safety & Environmental Protection Subcommittee Meeting. The meeting was held 18-21 March 2002 at the Sheraton Colorado Springs Hotel, Colorado Springs, Colorado. Topics covered include green energetic materials and life cycle pollution prevention; space launch range safety; propellant/munitions demilitarization, recycling, and reuse: and environmental and occupational health aspects of propellants and energetic materials.

  4. The Nordic Countries Meeting on the Zebrafish as a Model for Development and Disease 2012

    PubMed Central

    Zetterberg, Henrik

    2013-01-01

    Abstract The first Nordic Countries Meeting on the Zebrafish as a Model for Development and Disease took place at Karolinska Institutet in Stockholm, November 21–23, 2012. The meeting gathered 130 scientists, students, and company representatives from Iceland, Finland, Norway, Denmark, and Sweden, as well as invited guests and keynote speakers from England, Scotland, Germany, Poland, The Netherlands, Singapore, Japan, and the United States. Presentations covered a wide range of topics, including developmental biology, genetics, evolutionary biology, toxicology, behavioral studies, and disease mechanisms. The need for formal guidance and training in zebrafish housing, husbandry, and health monitoring was recognized, and the meeting expressed its support for the joint working group of the FELASA/COST action BM0804 EuFishBioMed. The decision was made to turn the Nordic meeting into an annual event and create a Nordic network of zebrafish researchers. PMID:23590403

  5. 77 FR 2040 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-13

    ... workshop. The workshop topic is volunteer angler data collection. DATES: The meeting will be held on...: (302) 526-5255. SUPPLEMENTARY INFORMATION: The workshop will include briefings on established volunteer... volunteer angler data collections and their uses. This workshop is a product of the Marine Recreational...

  6. Effects of topical phenytoin on nasal wound healing after mechanical trauma: An experimental study.

    PubMed

    Şimşek, Gökçe; Ciftci, Osman; Karadag, Neşe; Karatas, Erkan; Kizilay, Ahmet

    2014-12-01

    Impaired postoperative wound healing is the second most common morbidity after synechia formation in endoscopic sinus surgery. The aim of this experimental study was to investigate the potential effects of topical phenytoin on wound healing after nasal mucosal trauma in rats. An experimental study at the Inonu University Faculty of Medicine. Twenty-four rats were randomized into three groups: 1) phenytoin group (n = 8), 2) control group (n = 8), and 3) vehicle group (n = 8). After damaging the right nasal cavity, in the phenytoin group, 1% topical phenytoin cream was applied for 7 days. The rats in the control group did not receive any treatment. The vehicle group was treated with daily topical cold cream for 1 week. The rats were sacrificed at the end, and the nasal cavities were excised. Tissue edema and inflammatory cell infiltration were compared among the groups. Additionally, proliferating cell nuclear antigen (PCNA) and cluster of differentiation 31 (CD31) immunoexpression levels were evaluated. Furthermore, in biochemical analysis, the tissue levels of vascular endothelial growth factor and (EGF) of the groups were investigated. In the phenytoin group, tissue edema and inflammatory cell infiltration were significantly decreased, and PCNA and CD31 immunoexpression levels were more prominent (P < .001) and the tissue EGF levels were significantly higher (P < .01). Topical phenytoin treatment may alter the nasal wound healing after mechanical trauma. The potential beneficial effects of topical phenytoin on nasal mucosa should be investigated by further experimental and human trials. NA. © 2014 The American Laryngological, Rhinological and Otological Society, Inc.

  7. 76 FR 23352 - U.S. Advisory Commission on Public Diplomacy; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-26

    ... these and other topics relevant to its mission. This meeting is open to the public, the State Department... Crocker of Texas, Sim Farar of California, and Anne Wedner of Illinois. The Commission is a bipartisan...

  8. National Association for Research in Science Teaching (NARST). Annual Meeting (65th, Cambridge, Massachusetts, March 21-25, 1992). Abstracts of Presented Papers.

    ERIC Educational Resources Information Center

    Govindarajan, Girish, Ed.

    This product of an annual meeting presents abstracts of symposia, contributed papers, paper sets, discussion groups, reports, poster sessions, and panel presentations. Topics include: science teaching, gender differences, science education reform, constructivism, biological concepts, concept mapping, attitude/behavior change, conceptual…

  9. TopicLens: Efficient Multi-Level Visual Topic Exploration of Large-Scale Document Collections.

    PubMed

    Kim, Minjeong; Kang, Kyeongpil; Park, Deokgun; Choo, Jaegul; Elmqvist, Niklas

    2017-01-01

    Topic modeling, which reveals underlying topics of a document corpus, has been actively adopted in visual analytics for large-scale document collections. However, due to its significant processing time and non-interactive nature, topic modeling has so far not been tightly integrated into a visual analytics workflow. Instead, most such systems are limited to utilizing a fixed, initial set of topics. Motivated by this gap in the literature, we propose a novel interaction technique called TopicLens that allows a user to dynamically explore data through a lens interface where topic modeling and the corresponding 2D embedding are efficiently computed on the fly. To support this interaction in real time while maintaining view consistency, we propose a novel efficient topic modeling method and a semi-supervised 2D embedding algorithm. Our work is based on improving state-of-the-art methods such as nonnegative matrix factorization and t-distributed stochastic neighbor embedding. Furthermore, we have built a web-based visual analytics system integrated with TopicLens. We use this system to measure the performance and the visualization quality of our proposed methods. We provide several scenarios showcasing the capability of TopicLens using real-world datasets.

  10. University Press Meeting Dominated by Donor Proposal and Digital Publishing

    ERIC Educational Resources Information Center

    Howard, Jennifer

    2007-01-01

    A surprise request for proposals from the Andrew W. Mellon Foundation and a forthcoming report on university publishing in the digital age were among topics discussed at the annual meeting of the Association of American University Presses. The offer from the Mellon Foundation concerns support for collaborative, monograph-centered projects in…

  11. Extracting Hot spots of Topics from Time Stamped Documents

    PubMed Central

    Chen, Wei; Chundi, Parvathi

    2011-01-01

    Identifying time periods with a burst of activities related to a topic has been an important problem in analyzing time-stamped documents. In this paper, we propose an approach to extract a hot spot of a given topic in a time-stamped document set. Topics can be basic, containing a simple list of keywords, or complex. Logical relationships such as and, or, and not are used to build complex topics from basic topics. A concept of presence measure of a topic based on fuzzy set theory is introduced to compute the amount of information related to the topic in the document set. Each interval in the time period of the document set is associated with a numeric value which we call the discrepancy score. A high discrepancy score indicates that the documents in the time interval are more focused on the topic than those outside of the time interval. A hot spot of a given topic is defined as a time interval with the highest discrepancy score. We first describe a naive implementation for extracting hot spots. We then construct an algorithm called EHE (Efficient Hot Spot Extraction) using several efficient strategies to improve performance. We also introduce the notion of a topic DAG to facilitate an efficient computation of presence measures of complex topics. The proposed approach is illustrated by several experiments on a subset of the TDT-Pilot Corpus and DBLP conference data set. The experiments show that the proposed EHE algorithm significantly outperforms the naive one, and the extracted hot spots of given topics are meaningful. PMID:21765568

  12. Summary of Proceedings of ASIDIC Meeting (Arlington Park Towers Hotel, Arlington Heights, Illinois, September 26-28, 1971).

    ERIC Educational Resources Information Center

    Association of Scientific Information Dissemination Centers.

    The 1971 semi-annual ASIDIC (Association of Scientific Information Dissemination Centers) meeting held in Chicago was designed as a working session in which the topics of most concern to the member organizations could be discussed in detail. This report is a summary of those discussions. The broad topic headings for discussion were: (1)…

  13. Public understanding of geoscientific topics

    NASA Astrophysics Data System (ADS)

    Münch, Ute; Lauterjung, Jörn

    2014-05-01

    Geoscientific topics and their consequences for the society are becoming more and more important for our daily life. Natural hazards such as flood and storm or the consequences of the climate change are urgent tasks and great challenges we have to tackle. Cascading natural hazards or environmental risks, can't be evaluated as single events by one scientific discipline, they rather need the expertise of different experts. The same applies for slowly progressive processes such as the climate change and its different aftereffects. More than ever politicians, decision makers, but also the public are asking for comprehensive background information and data to discuss activity options and to develop sustainable solutions. The improvement of public knowledge about science, their assets and drawbacks, chances and risks is getting crucial. To paint a comprehensive picture of different factors, correlations and dependencies the pooling of expertise is required. Thus eight research centres of the research field "Earth and Environment" of the Helmholtz-Association, Germany's largest scientific research organisation are currently building up a knowledge platform. Scientists of different disciplines will provide background information and explain their latest findings in an understandable way. Infographics, maps and animations will be applied to simplify and interpret complicated facts and findings. In addition to the web presence target group-specific products and activities will be organized. To meet the expectations of the different stakeholders an intensive dialog is aspired: round table discussions, exhibitions in museums and public places, tweeds are envisaged. In the beginning the partners will concentrate on the topics "consequences of the climate change", "pollutant dispersion" and "natural hazards/meteorological extreme events". The project is called Earth System Knowledge Platform (ESKP) coordinated by the German Research Centre for Geosciences (GFZ) and the Helmholtz

  14. Overviews of Emerging Research Techniques in Hearing, Bioacoustics, and Biomechanics: Proceedings of the 1981 Meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    These proceedings of the 1981 annual meeting of the Committee on Hearing, Bioacoustics, and Biomechanics cover topics of emerging research in several areas of interest to the Committee. Topics covered include: hair cell function; transduction process of hair cells; speech synthesis; machine recognition of words; neuromagnetic analysis of sensory systems; tinnitus; tactile communication of speech; and biodynamic research at the Air Force Aerospace Medical Research Laboratory.

  15. ‘The concept of information in physics’: an interdisciplinary topical lecture

    NASA Astrophysics Data System (ADS)

    Dittrich, T.

    2015-01-01

    I present a didactical project, introducing the concept of information with all its interdisciplinary ramifications to students of physics and the neighbouring sciences. Proposed by Boltzmann as entropy, information has evolved into a common paradigm in science, economy, and culture, superseding energy in this role. As an integrating factor of the natural sciences at least, it lends itself as guiding principle for innovative teaching that transcends the frontiers of the traditional disciplines and emphasizes general viewpoints. Based on this idea, the postgraduate topical lecture presented here is intended to provide a firm conceptual basis, technically precise but versatile enough to be applied to specific topics from a broad range of fields. Basic notions of physics like causality, chance, irreversibility, symmetry, disorder, chaos, complexity can be reinterpreted on a common footing in terms of information and information flow. Dissipation and deterministic chaos, exemplifying information currents between macroscopic and microscopic scales, receive special attention. An important part is dedicated to quantum mechanics as an approach to physics that takes the finiteness of information systematically into account. Emblematic features like entanglement and non-locality appear as natural consequences. The course has been planned and tested for an audience comprising, besides physicists, students of other natural sciences as well as mathematics, informatics, engineering, sociology, and philosophy. I sketch history and objectives of this project, provide a resume of the course, report on experiences gained teaching it in various formats, and indicate possible future developments.

  16. Medicare Part D Payments for Topical Steroids

    PubMed Central

    Song, Hannah; Adamson, Adewole

    2017-01-01

    Importance Rising pharmaceutical costs in the United States are an increasing source of financial burden for payers and patients. Although topical steroids are among the most commonly prescribed medications in dermatology, there are limited data on steroid-related spending and utilization. Objective To characterize Medicare and patient out-of-pocket costs for topical steroids, and to model potential savings that could result from substitution of the cheapest topical steroid from the corresponding potency class. Design, Setting, and Participants This study was a retrospective cost analysis of the Medicare Part D Prescriber Public Use File, which details annual drug utilization and spending on both generic and branded drugs from 2011 to 2015 by Medicare Part D participants who filled prescriptions for topical steroids. Main Outcomes and Measures Total and potential Medicare and out-of-pocket patient spending. Costs were adjusted for inflation and reported in 2015 dollars. Results Medicare Part D expenditures on topical steroids between 2011 and 2015 were $2.3 billion. Patients’ out-of-pocket spending for topical steroids over the same period was $333.7 million. The total annual spending increased from $237.6 million to $775.9 million, an increase of 226.5%. Patients’ annual out-of-pocket spending increased from $41.4 million to $101.8 million, an increase of 145.9%. The total number of prescriptions were 7.7 million in 2011 and 10.6 million in 2015, an increase of 37.0%. Generic medication costs accounted for 97.8% of the total spending during this time period. The potential health care savings and out-of-pocket patient savings from substitution of the cheapest topical steroid within the corresponding potency class were $944.8 million and $66.6 million, respectively. Conclusions and Relevance Most topical steroids prescribed were generic drugs. There has been a sharp increase in Medicare and out-of-pocket spending on topical steroids that is driven by higher

  17. Designing Biological Systems for Sustainability and Programmed Environmental Interface (2011 JGI User Meeting)

    ScienceCinema

    Silver, Pamela

    2018-02-13

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Pam Silver of Harvard University gives a presentation on "Designing Biological Systems for Sustainability and Programmed Environmental Interface" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011.

  18. 77 FR 56241 - Board Meeting; October 17, 2012; Idaho Falls, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    .... Nuclear Waste Technical Review Board will meet to discuss DOE work on packaging, transporting, and...) plans for the packaging, transportation, and disposition of spent nuclear fuel (SNF) and high-level radioactive waste (HLW). Among the topics that will be discussed are current activities being undertaken by...

  19. The 4-H Club Meeting: An Essential Youth Development Strategy

    ERIC Educational Resources Information Center

    Cassels, Alicia; Post, Liz; Nestor, Patrick I.

    2015-01-01

    The club meeting has served as a key delivery method for 4-H programming across the United States throughout its history. A survey of WV 4-H community club members reinforces the body of evidence that the 4-H club meeting is an effective vehicle for delivering positive youth learning opportunities within the umbrella of the Essential Elements of…

  20. REPORT OF THE ISS OSI INVITED MEETING, VIENNA, 24-27 MARCH, 2009

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sweeney, J J

    2009-04-17

    The International Scientific Studies project (ISS) was initiated in early 2008 with the objective of creating a series of activities aimed at application of modern scientific methods to improve the efficiency of analysis and the quality of verification of the Comprehensive Nuclear Test-Ban Treaty Organization (CTBTO). The ISS On-Site Inspection (OSI) Invited Meeting convened on March 24, 2009 with the objectives of gaining a better understanding of the phenomenology of underground nuclear explosions (UNE) for OSI purposes and to identify areas of interest to OSI that could benefit significantly from contributions by the general scientific community. Fifteen invited experts frommore » four countries, along with fifteen members of the OSI Division of the Provisional Technical Secretariat (PTS) met for four days at the Vienna International Center in an informal setting to discuss the application of observational methods, geophysical techniques, radionuclide measurement methods, environmental sampling methods, drilling techniques, and information management in the context UNE phenomena and OSI implementation. The meeting began with the identification and description of two general OSI scenarios, a vertical borehole emplacement and a horizontal tunnel emplacement, that serve as general examples of past UNE testing activities that can be used as a reference to identify UNE phenomena relevant for OSI observations. A significant portion of the first day of the meeting was spent in the description of the details of these scenarios and their implications for OSI observables. This discussion then served as a foundation for the discussions of the following three days in which OSI methods and technologies were evaluated in the context of UNE phenomenology and signatures. The methods and technologies discussed included visual observation from air and ground, radiation detection from the air, ground, and subsurface, ground-based and airborne geophysical observations and

  1. An Uncommon Complication With Use of Topical Local Anesthetic Agents: Methemoglobinemia.

    PubMed

    Panikkath, Ragesh; Panikkath, Deepa; Wischmeyer, Jason

    Although the use of topical local anesthetics is generally safe, several potentially fatal complications have been reported. Methemoglobinemia is a rare but potentially fatal complication. Methemoglobin is a naturally occurring oxidized metabolite of hemoglobin, and physiologic levels (<1%) are normal. Methemoglobinemia can be congenital or acquired. Several drugs including topical anesthetic agents like benzocaine can induce this condition. Sudden appearance of cyanosis, with a disproportionately better oxygen saturation of 85% after use of local anesthetics can be a helpful for diagnosis.

  2. Anesthesia: A Topic for Interdisciplinary Study.

    ERIC Educational Resources Information Center

    Labianca, Dominick A.; Reeves, William J.

    1977-01-01

    Describes an interdisciplinary approach for teaching the topic of anesthesia as one aspect of a chemistry-oriented course for nonscience majors which focuses on timely topics such as the energy crisis and drugs. Historical treatment with the examination of literature is emphasized in teaching. (HM)

  3. 75 FR 9250 - Notice of Public Meeting, BLM-Alaska Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-01

    ... Land Management, on a variety of planning and management issues associated with public land management.... Manager reports. Stimulus projects update. Alaska Land Information System. National Landscape Conservation System anniversary. Resource management planning. Other topics of interest to the RAC. All meetings are...

  4. 76 FR 4380 - NASA Advisory Council; Audit, Finance and Analysis Committee; Meeting.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ..., Office of the Chief Financial Officer. (OCFO), National Aeronautics and Space Administration Headquarters... meeting includes the following topics: Review of FY2010 Financial Statement Audit and Roadmap to Unqualified Opinion in FY 2011. Chief Financial Officer Update and Review of OCFO Responsibilities. Financial...

  5. Delphi survey to identify topics to be addressed at the initial follow-up consultation after oesophageal cancer surgery.

    PubMed

    Jacobs, M; Henselmans, I; Macefield, R C; Blencowe, N S; Smets, E M A; de Haes, J C J M; Sprangers, M A G; Blazeby, J M; van Berge Henegouwen, M I

    2014-12-01

    There is no consensus among patients and healthcare professionals (HCPs) on the topics that need to be addressed after oesophageal cancer surgery. The aim of this study was to identify these topics, using a two-round Delphi survey. In round 1, patients and HCPs (surgeons, dieticians, nurses) were invited to rate the importance of 49 topics. The proportion of panellists that considered a topic to be of low, moderate or high importance was then calculated for each of these two groups. Based on these proportions and the i.q.r., topics were categorized as: 'consensus to be included', 'consensus to be excluded' and 'no consensus'. Only topics in the first category were included in the second round. In round 2, panellists were provided with individual and group feedback. To be included in the final list, topics had to meet criteria for consensus and stability. There were 108 patients and 77 HCPs in the round 2 analyses. In general, patients and HCPs considered the same topics important. The final list included 23 topics and revealed that it was most important to address: cancer removed/lymph nodes, the new oesophagus, eating and drinking, surgery, alarming new complaints and the recovery period. The study provides surgeons with a list of topics selected by patients and HCPs that may be addressed systematically at the initial follow-up consultation after oesophageal cancer surgery. © 2014 BJS Society Ltd. Published by John Wiley & Sons Ltd.

  6. 2nd Annual DOE-ERSP PI Meeting: Abstracts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hazen, Terry C.

    2007-03-14

    presentations and allows ample time for informal group discussions and poster presentations. The intent of this format is to foster informal discussion of research among PIs and ERSD program managers-discussion that is a hallmark of previous ERSD-sponsored meetings. Morning sessions will be dominated by oral presentations from PIs chosen by ERSD program managers to communicate key topics of research within the program. There is ample time during lunch and in the early afternoon for small group discussions/meetings prior to convening again in the later afternoon for oral presentations on field research conducted at the Integrated Field-Scale Subsurface Research Challenge sites (IFCs). Formal poster sessions begin after dinner. Abstracts for all poster presentations are listed within this meeting booklet. On behalf of the ERSD program managers and staff, we thank you for attending this year's PI meeting. We look forward to discussing the results of your research with you and your ideas for the future, and we hope that this meeting will continue as an important tradition for PIs in the program and serve as a valuable resource for your investigations.« less

  7. Successful Public Relations Efforts: Using the Departmental Meeting as a Resource.

    ERIC Educational Resources Information Center

    Seewald, Jacqueline

    1998-01-01

    Explains how media specialists can use departmental meetings to develop and promote better public relations within the school community. Topics include changes in the media center; new programs or services being offered, including new software and Internet resources; teacher requests for materials to support their curriculum; and interlibrary-loan…

  8. Topical Rosiglitazone Is an Effective Anti-Scarring Agent in the Cornea

    PubMed Central

    Huxlin, Krystel R.; Hindman, Holly B.; Jeon, Kye-Im; Bühren, Jens; MacRae, Scott; DeMagistris, Margaret; Ciufo, David; Sime, Patricia J.; Phipps, Richard P.

    2013-01-01

    Corneal scarring remains a major cause of blindness world-wide, with limited treatment options, all of which have side-effects. Here, we tested the hypothesis that topical application of Rosiglitazone, a Thiazolidinedione and ligand of peroxisome proliferator activated receptor gamma (PPARγ), can effectively block scar formation in a cat model of corneal damage. Adult cats underwent bilateral epithelial debridement followed by excimer laser ablation of the central corneal stroma to a depth of ∼160 µm as a means of experimentally inducing a reproducible wound. Eyes were then left untreated, or received 50 µl of either 10 µM Rosiglitazone in DMSO/Celluvisc, DMSO/Celluvisc vehicle or Celluvisc vehicle twice daily for 2 weeks. Cellular aspects of corneal wound healing were evaluated with in vivo confocal imaging and post-mortem immunohistochemistry for alpha smooth muscle actin (αSMA). Impacts of the wound and treatments on optical quality were assessed using wavefront sensing and optical coherence tomography at 2, 4, 8 and 12 weeks post-operatively. In parallel, cat corneal fibroblasts were cultured to assess the effects of Rosiglitazone on TGFβ-induced αSMA expression. Topical application of Rosiglitazone to cat eyes after injury decreased αSMA expression and haze, as well as the induction of lower-order and residual, higher-order wavefront aberrations compared to vehicle-treated eyes. Rosiglitazone also inhibited TGFβ-induced αSMA expression in cultured corneal fibroblasts. In conclusion, Rosiglitazone effectively controlled corneal fibrosis in vivo and in vitro, while restoring corneal thickness and optics. Its topical application may represent an effective, new avenue for the prevention of corneal scarring with distinct advantages for pathologically thin corneas. PMID:23940641

  9. Cosmic dust and space debris; Proceedings of the Topical Meetings and Workshop 6 of the 26th COSPAR Plenary Meeting, Toulouse, France, June 30-July 11, 1986

    NASA Technical Reports Server (NTRS)

    Mcdonnell, J. A. M. (Editor); Hanner, M. S. (Editor); Kessler, D. J. (Editor)

    1986-01-01

    These proceedings encompass topics in the fields of extraterrestrial material samples, IRAS solar system and dust model results, and earth orbit debris. Attention is given to chemical fractionation during high velocity impact, particle deceleration and survival in multiple thin foil targets, and IRAS studies of asteroids, comets, cometary tails, the zodiacal background, and the three-dimensional modeling of interplanetary dust. Also discussed are the evolution of an earth orbit debris cloud, orbital debris due to future space activities, collision probabilities in geosynchronous orbits, and a bitelescopic survey of low altitude orbital debris.

  10. 75 FR 29353 - National Advisory Committee on Rural Health and Human Services; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-25

    ... Subcommittee topics. The first panel will focus on childhood obesity in rural communities. The second panel... Childhood Obesity Subcommittee and the Young Children's Initiative Subcommittee will meet at Eat Smart, Move...

  11. 76 FR 44011 - Medicare Program; Meeting of the Medicare Evidence Development and Coverage Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ...-VEGF) treatment of diabetic macular edema (DME). This meeting is open to the public in accordance with... macular edema (DME). Background information about this topic, including panel materials, is available at...

  12. IP Internal Movement and Topicalization

    ERIC Educational Resources Information Center

    Kuo, Pei-Jung

    2009-01-01

    In this dissertation, I investigate the phenomenon of internal topicalization cross-linguistically, using Chinese as a starting point. Internal topicalization refers to constructions in which a topic phrase is placed between the subject and the verb (in contrast to external topicalization, which involves a topic in the CP domain). I argue that…

  13. 75 FR 23222 - National Poultry Improvement Plan; General Conference Committee Meeting and 40th Biennial Conference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-03

    ... the NPIP program. Tentative topics for discussion at the upcoming meetings include: 1. Salmonella enteritidis in meat-type chickens. 2. Salmonella isolation and identification protocol. 3. Notifiable avian...

  14. 75 FR 38147 - NASA Advisory Council; Education and Public Outreach Committee; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... via WebEx. Any interested person should contact Ms. Erika G. Vick, Executive Secretary for the... teleconference and/or WebEx. SUPPLEMENTARY INFORMATION: The agenda for the meeting includes the following topics: Summer of Innovation Program Social Media Successes, Opportunities, and Challenges Regulations that...

  15. 78 FR 60309 - Notice of Public Meeting, BLM-Alaska Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    [email protected] . Persons who use a telecommunications device for the deaf (TDD) may call the Federal... variety of planning and management issues associated with public land management in Alaska. At this meeting, topics planned for discussion include: Land Use Planning. Integrated Arctic Management and...

  16. 78 FR 28221 - Advisory Council for the Elimination of Tuberculosis Meeting (ACET)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... Council for the Elimination of Tuberculosis Meeting (ACET) In accordance with section 10(a)(2) of the... for Health, and the Director, CDC, regarding the elimination of tuberculosis. Specifically, the... eliminating tuberculosis. Matters To Be Discussed: Agenda items include the following topics: 1) Tuberculosis...

  17. Learning topic models by belief propagation.

    PubMed

    Zeng, Jia; Cheung, William K; Liu, Jiming

    2013-05-01

    Latent Dirichlet allocation (LDA) is an important hierarchical Bayesian model for probabilistic topic modeling, which attracts worldwide interest and touches on many important applications in text mining, computer vision and computational biology. This paper represents the collapsed LDA as a factor graph, which enables the classic loopy belief propagation (BP) algorithm for approximate inference and parameter estimation. Although two commonly used approximate inference methods, such as variational Bayes (VB) and collapsed Gibbs sampling (GS), have gained great success in learning LDA, the proposed BP is competitive in both speed and accuracy, as validated by encouraging experimental results on four large-scale document datasets. Furthermore, the BP algorithm has the potential to become a generic scheme for learning variants of LDA-based topic models in the collapsed space. To this end, we show how to learn two typical variants of LDA-based topic models, such as author-topic models (ATM) and relational topic models (RTM), using BP based on the factor graph representations.

  18. Integrated Photonics Research Topical Meeting (1993)

    DTIC Science & Technology

    1994-06-01

    81 DMD Time Domain Methods .................................. 107 IME Photonic Circuits and Lightwave Reception...index change near the band edge using a small interference -ellipsometry bridge and presented several results of nt of refractive index change An[51. In... interference -ellipsometry bridge at the photon energies near Eg, especially E>Eg, and compared to previous theories. [11. Manning, R Olshans]y, and C. B. Su

  19. Beyond the androgen receptor II: New approaches to understanding and treating metastatic prostate cancer; Report from the 2017 Coffey-Holden Prostate Cancer Academy Meeting.

    PubMed

    Miyahira, Andrea K; Cheng, Heather H; Abida, Wassim; Ellis, Leigh; Harshman, Lauren C; Spratt, Daniel E; Simons, Jonathan W; Pienta, Kenneth J; Soule, Howard R

    2017-11-01

    The 2017 Coffey-Holden Prostate Cancer Academy (CHPCA) Meeting, "Beyond the Androgen Receptor II: New Approaches to Understanding and Treating Metastatic Prostate Cancer," was held in Carlsbad, California from June 14-17, 2017. The CHPCA is an annual scientific conference hosted by the Prostate Cancer Foundation (PCF) that is uniquely designed to produce extensive and constructive discussions on the most urgent and impactful topics concerning research into the biology and treatment of metastatic prostate cancer. The 2017 CHPCA Meeting was the 5th meeting in this annual series and was attended by 71 investigators focused on prostate cancer and a variety of other fields including breast and ovarian cancer. The discussions at the meeting were concentrated on topics areas including: mechanisms and therapeutic approaches for molecular subclasses of castrate resistant prostate cancer (CRPC), the epigenetic landscape of prostate cancer, the role of DNA repair gene mutations, advancing the use of germline genetics in clinical practice, radionuclides for imaging and therapy, advances in molecular imaging, and therapeutic strategies for successful use of immunotherapy in advanced prostate cancer. This article reviews the presentations and discussions from the 2017 CHPCA Meeting in order to disseminate this knowledge and accelerate new biological understandings and advances in the treatment of patients with metastatic prostate cancer. © 2017 Wiley Periodicals, Inc.

  20. Coordinating Council. Fourth Meeting: NACA Documents Database Project

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This NASA Scientific and Technical Information Coordination Council meeting dealt with the topic 'NACA Documents Database Project'. The following presentations were made and reported on: NACA documents database project study plan, AIAA study, the Optimal NACA database, Deficiencies in online file, NACA documents: Availability and Preservation, the NARA Collection: What is in it? and What to do about it?, and NACA foreign documents and availability. Visuals are available for most presentations.

  1. Group Discussion Topics. Revised Edition.

    ERIC Educational Resources Information Center

    Area Education Agency 7, Cedar Falls, IA.

    A collection of group disussion topics, developed and field-tested by a group of Iowa teachers, is presented in this guide. Twenty-eight topics for K-6 students, 24 topics for K-12 students, and 7 topics for students in grades 7-12 are included. Warm-up activities are given for introducing some of the topics, and lists of questions to provoke…

  2. How Hierarchical Topics Evolve in Large Text Corpora.

    PubMed

    Cui, Weiwei; Liu, Shixia; Wu, Zhuofeng; Wei, Hao

    2014-12-01

    Using a sequence of topic trees to organize documents is a popular way to represent hierarchical and evolving topics in text corpora. However, following evolving topics in the context of topic trees remains difficult for users. To address this issue, we present an interactive visual text analysis approach to allow users to progressively explore and analyze the complex evolutionary patterns of hierarchical topics. The key idea behind our approach is to exploit a tree cut to approximate each tree and allow users to interactively modify the tree cuts based on their interests. In particular, we propose an incremental evolutionary tree cut algorithm with the goal of balancing 1) the fitness of each tree cut and the smoothness between adjacent tree cuts; 2) the historical and new information related to user interests. A time-based visualization is designed to illustrate the evolving topics over time. To preserve the mental map, we develop a stable layout algorithm. As a result, our approach can quickly guide users to progressively gain profound insights into evolving hierarchical topics. We evaluate the effectiveness of the proposed method on Amazon's Mechanical Turk and real-world news data. The results show that users are able to successfully analyze evolving topics in text data.

  3. Spatially and Temporally Resolved Studies of the Human Microbiome (2011 JGI User Meeting)

    ScienceCinema

    Knight, Rob

    2018-04-26

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Rob Knight of the University of Colorado gives a presentation on "Spatially and Temporally Resolved Studies of the Human Microbiome" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011.

  4. Face-offs in reproductive immunology: the Montreal forum meeting report.

    PubMed

    Croy, B Anne; Baines, Malcolm G

    2004-10-01

    The combined 12th International Congress of Immunology (ICI) and the 4th Annual Conference of the Federation of Clinical Immunological Societies (FOCIS) was held in Montreal, Canada July 18-23, 2004 and attracted over 6000 immunologists and almost 4000 abstracts. The host society, the Canadian Society for Immunology (CSI) spent many years in preparation for this large meeting and encouraged its members to propose topics for symposia and mini-symposia and to sponsor satellite meetings. With sponsorship of CSI; the Canadian Institutes of Health Research; the University of Guelph, Guelph, ON; Queen's University, Kingston, ON; McGill University, Montreal, QU, Canada; and the American Society for Reproductive Immunology, a focused, highly successful, one day satellite meeting on human uterine immunology was held. The highlights of the presentations and discussions are reported.

  5. The value of multidisciplinary team meetings within an early pregnancy assessment unit.

    PubMed

    Bharathan, Rasiah; Farag, Mena; Hayes, Kevin

    2016-08-01

    This is the first study to ascertain the value of multidisciplinary team (MDT) meetings within an early pregnancy assessment unit (EPAU). Our national telephone survey identified that in the United Kingdom, overall 37% of EPAU utilise regular MDT meetings. Secondary and tertiary hospitals are just as likely to hold regular MDT meetings. The participants in our interview study expressed the principal benefits of regular MDT meetings as communication, education and effective stress management. The perceived additional benefits included improved care quality, better patient experience and enhanced team cohesion. During the meetings, at least, one representative from every tier of staffing was present. The caseload of the MDT meeting comprised ectopic pregnancies and pregnancies of unknown location. We propose a number of research studies, which would build on this study. Such efforts will help enhance the effectiveness of the MDT-based EPAU service.

  6. Meeting report: Metastasis Research Society-Chinese Tumor Metastasis Society joint conference on metastasis.

    PubMed

    Bankaitis, Katherine; Borriello, Lucia; Cox, Thomas; Lynch, Conor; Zijlstra, Andries; Fingleton, Barbara; Gužvić, Miodrag; Anderson, Robin; Neman, Josh

    2017-04-01

    During September 16th-20th 2016, metastasis experts from around the world convened for the 16th Biennial Congress of the Metastasis Research Society and 12th National Congress of the Chinese Tumor Metastasis Society in Chengdu, China to share most current data covering basic, translational, and clinical metastasis research. Presentations of the more than 40 invited speakers of the main congress and presentations from the associated Young Investigator Satellite Meeting are summarized in this report by session topic. The congress program also included three concurrent short talk sessions, an advocacy forum with Chinese and American metastatic patient advocates, a 'Meet the Professors Roundtable' session for young investigators, and a 'Meet the Editors' session with editors from Cancer Cell and Nature Cell Biology. The goal of integrating expertise and exchanging the latest findings, ideas, and practices in cancer metastasis research was achieved magnificently, thanks to the excellent contributions of many leaders in the field.

  7. 78 FR 9925 - Advisory Council for the Elimination of Tuberculosis Meeting (ACET)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... Council for the Elimination of Tuberculosis Meeting (ACET) In accordance with section 10(a)(2) of the... Health, and the Director, CDC, regarding the elimination of tuberculosis. Specifically, the Council makes... tuberculosis. Matters to Be Discussed: Agenda items include the following topics: (1) ACET Chair's report to...

  8. 76 FR 27661 - Notice of Public Meeting; Western Montana Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-12

    ... several topics, including reports from the Bureau of Land Management's Butte, Missoula and Dillon field... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLMTB07900 09 L10100000.PH0000 LXAMANMS0000] Notice of Public Meeting; Western Montana Resource Advisory Council AGENCY: Bureau of Land Management...

  9. Meeting report from the Prostate Cancer Foundation PSMA-directed radionuclide scientific working group.

    PubMed

    Miyahira, Andrea K; Pienta, Kenneth J; Morris, Michael J; Bander, Neil H; Baum, Richard P; Fendler, Wolfgang P; Goeckeler, William; Gorin, Michael A; Hennekes, Hartwig; Pomper, Martin G; Sartor, Oliver; Tagawa, Scott T; Williams, Scott; Soule, Howard R

    2018-05-01

    The Prostate Cancer Foundation (PCF) convened a PSMA-Directed Radionuclide Scientific Working Group on November 14, 2017, at Weill Cornell Medicine, New York, NY. The meeting was attended by 35 global investigators with expertise in prostate cancer biology, radionuclide therapy, molecular imaging, prostate-specific membrane antigen (PSMA)-targeted agents, drug development, and prostate cancer clinical trials. The goal of this meeting was to discuss the potential for using PSMA-targeted radionuclide agents for the treatment of advanced prostate cancer and to define the studies and clinical trials necessary for validating and optimizing the use of these agents. Several major topic areas were discussed including the overview of PSMA biology, lessons and applications of PSMA-targeted PET imaging, the nuances of designing PSMA-targeted radionuclide agents, clinical experiences with PSMA-targeted radionuclides, PCF-funded projects to accelerate PSMA-targeted radionuclide therapy, and barriers to the use of radionuclide treatments in widespread clinical practice. This article reviews the major topics discussed at the meeting with the goal of promoting research that will validate and optimize the use of PSMA-targeted radionuclide therapies for the treatment of advanced prostate cancer. © 2018 Wiley Periodicals, Inc.

  10. Fish from Head to Tail: The 9th European Zebrafish Meeting in Oslo.

    PubMed

    Griffiths, Gareth; Müller, Ferenc; Ledin, Johan; Patton, E Elizabeth; Gjøen, Tor; Lobert, Viola Hélène; Winther-Larsen, Hanne Cecilie; Mullins, Mary; Joly, Jean-Stephane; Weltzien, Finn-Arne; Press, Charles McLean; Aleström, Peter

    2016-04-01

    The 9th European Zebrafish Meeting took place recently in Oslo (June 28-July 2, 2015). A total of 650 participants came to hear the latest research news focused on the zebrafish, Danio rerio, and to its distant evolutionary relative medaka, Oryzias latipes. The packed program included keynote and plenary talks, short oral presentations and poster sessions, workshops, and strategic discussions. The meeting was a great success and revealed dramatically how important the zebrafish in particular has become as a model system for topics, such as developmental biology, functional genomics, biomedicine, toxicology, and drug development. A new emphasis was given to its potential as a model for aquaculture, a topic of great economic interest to the host country Norway and for the future global food supply in general. Zebrafish husbandry as well as its use in teaching were also covered in separate workshops. As has become a tradition in these meetings, there was a well-attended Wellcome Trust Sanger Institute and ZFIN workshop focused on Zebrafish Genome Resources on the first day. The full EZM 2015 program with abstracts can be read and downloaded from the EZM 2015 Web site zebrafish2015.org .

  11. 75 FR 16438 - U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S... Tourism Advisory Board (Board) will hold a meeting to discuss topics related to the travel and tourism...

  12. Latest discoveries and trends in translational cancer research: highlights of the 2008 Annual Meeting of the American Association for Cancer Research.

    PubMed

    Cho, William C S

    2008-08-01

    The Annual Meeting of the American Association for Cancer Research (AACR) is the world's largest and most comprehensive gathering of cancer researchers. At the 2008 AACR Annual Meeting, innovative research approaches, novel technologies, potentially life-saving therapies in the pipeline, late-breaking clinical trial findings, and new approaches to cancer prevention were presented by top scientists. Reflecting the global state of cancer research with an eye toward future trends, several areas of great science and discovery in the cancer field were shared in this report, which include cancer biomarkers, the role of microRNAs in cancer research, cancer stem cells, tumor microenvironment, targeted therapy, and cancer prevention. This article presents an overview of hot topics discussed at the 2008 AACR Annual Meeting and recapitulates some scientific sessions geared toward new technologies, recent progress, and current challenges reported by cancer researchers. For those who did not attend the meeting, this report may serve as a highlight of this important international cancer research meeting.

  13. Topic Structure Affects Semantic Integration: Evidence from Event-Related Potentials

    PubMed Central

    Yang, Xiaohong; Chen, Xuhai; Chen, Shuang; Xu, Xiaoying; Yang, Yufang

    2013-01-01

    This study investigated whether semantic integration in discourse context could be influenced by topic structure using event-related brain potentials. Participants read discourses in which the last sentence contained a critical word that was either congruent or incongruent with the topic established in the first sentence. The intervening sentences between the first and the last sentence of the discourse either maintained or shifted the original topic. Results showed that incongruent words in topic-maintained discourses elicited an N400 effect that was broadly distributed over the scalp while those in topic-shifted discourses elicited an N400 effect that was lateralized to the right hemisphere and localized over central and posterior areas. Moreover, a late positivity effect was only elicited by incongruent words in topic-shifted discourses, but not in topic-maintained discourses. This suggests an important role for discourse structure in semantic integration, such that compared with topic-maintained discourses, the complexity of discourse structure in topic-shifted condition reduces the initial stage of semantic integration and enhances the later stage in which a mental representation is updated. PMID:24348994

  14. Topic structure affects semantic integration: evidence from event-related potentials.

    PubMed

    Yang, Xiaohong; Chen, Xuhai; Chen, Shuang; Xu, Xiaoying; Yang, Yufang

    2013-01-01

    This study investigated whether semantic integration in discourse context could be influenced by topic structure using event-related brain potentials. Participants read discourses in which the last sentence contained a critical word that was either congruent or incongruent with the topic established in the first sentence. The intervening sentences between the first and the last sentence of the discourse either maintained or shifted the original topic. Results showed that incongruent words in topic-maintained discourses elicited an N400 effect that was broadly distributed over the scalp while those in topic-shifted discourses elicited an N400 effect that was lateralized to the right hemisphere and localized over central and posterior areas. Moreover, a late positivity effect was only elicited by incongruent words in topic-shifted discourses, but not in topic-maintained discourses. This suggests an important role for discourse structure in semantic integration, such that compared with topic-maintained discourses, the complexity of discourse structure in topic-shifted condition reduces the initial stage of semantic integration and enhances the later stage in which a mental representation is updated.

  15. Exploring communication processes in workplace meetings: A mixed methods study in a Swedish healthcare organization

    PubMed Central

    Bergman, Caroline; Dellve, Lotta; Skagert, Katrin

    2016-01-01

    BACKGROUND: An efficient team and a good organizational climate not only improve employee health but also the health and safety of the patients. Building up trust, a good organizational climate and a healthy workplace requires effective communication processes. In Sweden, workplace meetings as settings for communication processes are regulated by a collective labor agreement. However, little is known about how these meetings are organized in which communication processes can be strengthened. OBJECTIVE: The aim of this study was to explore communication processes during workplace meetings in a Swedish healthcare organization. METHODS: A qualitatively driven, mixed methods design was used with data collected by observations, interviews, focus group interviews and mirroring feedback seminars. Data were analyzed using descriptive statistics and conventional content analysis. RESULTS: The communication flow and the organization of the observed meetings varied in terms of physical setting, frequency, time allocated and duration. The topics for the workplace meetings were mainly functional with a focus on clinical processes. Overall, the meetings were viewed not only as an opportunity to communicate information top down but also a means by which employees could influence decision-making and development at the workplace. CONCLUSIONS: Workplace meetings have very distinct health-promoting value. It emerged that information and the opportunity to influence decisions related to workplace development are important to the workers. These aspects also affect the outcome of the care provided. PMID:27472854

  16. eHealth Technologies as an intervention to improve adherence to topical antipsoriatics: a systematic review.

    PubMed

    Svendsen, Mathias Tiedemann; Andersen, Flemming; Andersen, Klaus Ejner

    2018-03-01

    Topical antipsoriatics are recommended first-line treatment of psoriasis, but rates of adherence are low. Patient support by use of electronic health (eHealth) services is suggested to improve medical adherence. To review randomised controlled trials (RCTs) testing eHealth interventions designed to improve adherence to topical antipsoriatics and to review applications for smartphones (apps) incorporating the word psoriasis. Literature review: Medline, Embase, Cochrane, PsycINFO and Web of Science were searched using search terms for eHealth, psoriasis and topical antipsoriatics. General analysis of apps: The operating systems (OS) for smartphones, iOS, Google Play, Microsoft Store, Symbian OS and Blackberry OS were searched for apps containing the word psoriasis. Literature review: Only one RCT was included, reporting on psoriasis patients' Internet reporting their status of psoriasis over a 12-month period. The rate of adherence was measured by Medication Event Monitoring System (MEMS ® ). An improvement in medical adherence and reduction of severity of psoriasis were reported. General analysis of apps: A total 184 apps contained the word psoriasis. There is a critical need for high-quality RCTs testing if the ubiquitous eHealth technologies, for example, some of the numerous apps, can improve psoriasis patients' rates of adherence to topical antipsoriatics.

  17. Classroom Meetings: An Approach to Transpersonal Education.

    ERIC Educational Resources Information Center

    DeVoe, Marianne

    1979-01-01

    Glasser's classroom meetings provide a promising structure for teachers' transpersonal skills and for providing a forum for discussion of transpersonal experiences, concerns, and questions. A preplanning worksheet developed by Bosner and Poppen demonstrating how to use the thinking meeting as a medium to teach relaxation skills is presented here.…

  18. NASA MEVTV Program Working Group Meeting: Volcanism on Mars

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The purpose of this working group meeting is to focus predominantly on volcanism on Mars, prior to considering the more complex issues of interactions between volcanism and tectonism or between volcanism and global or regional volatile evolution. It is also hoped that the topical areas of research identified will aid the planetary geology community in understanding volcanism on Mars and its relationship to other physical processes.

  19. In Situ Resource Utilization (ISRU II) Technical Interchange Meeting

    NASA Technical Reports Server (NTRS)

    Kaplan, David (Compiler); Saunders, Stephen R. (Compiler)

    1997-01-01

    This volume contains extended abstracts that have been accepted for presentation at the In Situ Resource Utilization (ISRU II) Technical Interchange Meeting, November 18-19, 1997, at the Lunar and Planetary Institute, Houston, Texas. Included are topics which include: Extraterrestrial resources, in situ propellant production, sampling of planetary surfaces, oxygen production, water vapor extraction from the Martian atmosphere, gas generation, cryogenic refrigeration, and propellant transport and storage.

  20. JANNAF 35th Combustion Subcommittee Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Fry, Ronald S. (Editor); Gannaway, Mary T. (Editor); Rognan, Melanie (Editor)

    1998-01-01

    Volume 1, the first of two volumes is a compilation of 63 unclassified/unlimited distribution technical papers presented at the 35th meeting of the Joint Army-Navy-NASA-Air Force (JANNAF) Combustion Subcommittee (CS) held jointly with the 17th Propulsion Systems Hazards Subcommittee (PSHS) and Airbreathing Propulsion Subcommittee (APS). The meeting was held on 7-11 December 1998 at Raytheon Systems Company and the Marriott Hotel, Tucson, AZ. Topics covered include solid gun propellant processing, ignition and combustion, charge concepts, barrel erosion and flash, gun interior ballistics, kinetics and molecular modeling, ETC gun modeling, simulation and diagnostics, and liquid gun propellant combustion; solid rocket motor propellant combustion, combustion instability fundamentals, motor instability, and measurement techniques; and liquid and hybrid rocket combustion.

  1. Impact on quality activities of measurement systems meeting an L:1 rule

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hamada, M. S.; Burkhardt, J. H.

    2016-04-01

    This study considers the impact of a measurement system that meets an L:1 rule on various quality activities. These activities include inspection, acceptance sampling, and control charting. A measurement system that meets a 10:1 rule performs much better than one that meets a 4:1 rule. R code is provided so that the practitioner is able to evaluate these activities to his or her particular situation.

  2. Human Factors Topics in Flight Simulation: An Annotated Bibliography

    DTIC Science & Technology

    1976-01-01

    and technical information; - Continuously stimulating advances in the aerospace sciences relevant to strengthening the common defence posture...Topics treated under cost effectiveness are effectiveness as a function of training procedures, physical stimulation versus psychological stimulation ...fidelity of physical stimulation . HUDDLESTON. H.F. and ROLFE, J.M. Behaviouralfactors influencing aircrew response in training and research simulators

  3. 78 FR 20696 - NASA Advisory Council; Human Exploration and Operations Committee; Research Subcommittee; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: 13-042] NASA Advisory Council; Human Exploration and Operations Committee; Research Subcommittee; Meeting AGENCY: National Aeronautics and Space... topics: --Overview of Research in Space Life and Physical Sciences --Space Station and Future Exploration...

  4. Monitoring Across Borders: 2010 Joint Meeting of the Forest Inventory and Analysis (FIA) Symposium and the Southern Mensurationists

    Treesearch

    Will McWilliams; Francis A. Roesch

    2012-01-01

    These proceedings represent the range of topics covered during the 2010 Joint Meeting of the Forest Inventory and Analysis (FIA) Symposium and the Southern Mensurationists, October 5-7, 2010 in Knoxville, TN. The meeting was a gathering of forest scientists with a quantitative leaning and, as such, the papers discuss the aspects of the observation, estimation, modeling...

  5. Methotrexate for topical application in an extemporaneous preparation.

    PubMed

    Wohlrab, Johannes; Neubert, Reinhard H H; Michael, Julia; Naumann, Sandy

    2015-09-01

    The antifolate agent methotrexate is routinely used for systemic therapy of cancer and chronic inflammatory diseases. Successful topical use has been described for individual therapeutic attempts, in case series, and small studies, especially for mycosis fungoides (premycotic stage) and lymphomatoid papulosis. With respect to its clinical use in selected treatment scenarios, there have been no approved preparations or regulated instructions for pharmaceutical compounding. Two high performance liquid chromatography methods were established for the determination of the active substance within a galenic formulation as well as within extracts of biological material. Suitable vehicles for epicutaneous application were developed and preclinically tested for stability, release, and pharmacokinetics of the active substance as well as their safety. The tests show that methotrexate may be readily incorporated into "Basiscreme DAC". It remains stable up to a concentration of 0.5%. This preparation releases enough active substance to achieve relevant local bioavailability in the respective target compartments of the skin. There is no evidence of safety risks due to relevant systemic bioavailability after topical application on a limited area of the skin. In summary, this approved prescription for extemporaneous preparation complies with the requirements of the German Ordinance on the Operation of Pharmacies (Article 7 ApBetrO), and the available data proves its stability and pharmaceutical quality. © 2015 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  6. Topical anesthesia in phacoemulsification.

    PubMed

    Waheeb, Saad

    2010-09-01

    To evaluate the efficacy of topical anesthesia; topical Benoxinate 0.4% (Oxybuprocaine) and Xylocaine (Lidocaine) gel, in selected cataract patients as an alternative to peribulbar or retrobulbar block anesthesia during cataract surgery. Prospective non-comparative evaluation of patients' and surgeon's satisfaction at the end of the procedure. Three hundred patients (300 eyes) were included in the study. The procedure was explained to patients with details regarding what will happen and what to expect during surgery. All patients received topical anesthesia with Benoxinate 0.4% eye drops and Xylocaine gel 2%. All surgeries were done by the same surgeon using the same machine (updated LEGACY phacoemulsifier, Alcon) and approach (clear corneal incision) and followed by a foldable intraocular lens (IOL) implantation. None of the patients had severe pain during the procedure; only 2% (six of 300) required use of intravenous sedation (Propofol), both the surgeon's and the patients' satisfaction were high. Eye movements and blepharospasm were not significant problems, and no serious complications occurred. Rate of vitreous loss due to posterior capsule tear/rupture was within literature reported range and not different from our previous experience. Topical anesthesia is a satisfactory and safe alternative to retrobulbar and peribulbar anesthesia for clear corneal phacoemulsification and intraocular lens implantation in selected cataract patients in the hands of experienced cataract surgeon.

  7. Topical anesthesia in phacoemulsification

    PubMed Central

    Waheeb, Saad

    2010-01-01

    Purpose: To evaluate the efficacy of topical anesthesia; topical Benoxinate 0.4% (Oxybuprocaine) and Xylocaine (Lidocaine) gel, in selected cataract patients as an alternative to peribulbar or retrobulbar block anesthesia during cataract surgery. Materials and Methods: Prospective non-comparative evaluation of patients’ and surgeon’s satisfaction at the end of the procedure. Three hundred patients (300 eyes) were included in the study. The procedure was explained to patients with details regarding what will happen and what to expect during surgery. All patients received topical anesthesia with Benoxinate 0.4% eye drops and Xylocaine gel 2%. All surgeries were done by the same surgeon using the same machine (updated LEGACY phacoemulsifier, Alcon) and approach (clear corneal incision) and followed by a foldable intraocular lens (IOL) implantation. Results: None of the patients had severe pain during the procedure; only 2% (six of 300) required use of intravenous sedation (Propofol), both the surgeon’s and the patients’ satisfaction were high. Eye movements and blepharospasm were not significant problems, and no serious complications occurred. Rate of vitreous loss due to posterior capsule tear/rupture was within literature reported range and not different from our previous experience. Conclusion: Topical anesthesia is a satisfactory and safe alternative to retrobulbar and peribulbar anesthesia for clear corneal phacoemulsification and intraocular lens implantation in selected cataract patients in the hands of experienced cataract surgeon. PMID:21120050

  8. Salicylic Acid Topical

    MedlinePlus

    ... stinging in the area where you applied topical salicylic acid Some side effects can be serious. If you experience any of ... of the eyes, face, lips, or tongue Topical salicylic acid may cause other side effects. Call your doctor if you have any unusual ...

  9. Learning Spaces in Higher Education: An Under-Researched Topic

    ERIC Educational Resources Information Center

    Temple, Paul

    2008-01-01

    The connections between the design and use of space in higher education, and the production of teaching and learning, and of research, are not well understood. This paper reports on a literature review on these topics, and shows that higher education spaces can be considered in various ways: in terms of campus design, in terms of how space can…

  10. Meeting report on the ASM Conference on Mechanisms of Interbacterial Cooperation and Competition.

    PubMed

    Lories, Bram; Parijs, Ilse; Foster, Kevin R; Steenackers, Hans P

    2017-08-14

    The ASM Conference on Mechanisms of Interbacterial Cooperation and Competition was held in Washington DC, from 1 to 4 March 2017. The conference provided an international forum for sociomicrobiologists from different disciplines to present and discuss new findings. The meeting covered a wide range of topics, spanning molecular mechanisms, ecology, evolution, computation and manipulation of interbacterial interactions, and encompassed social communities in medicine, the natural environment, and industry. This report summarizes the presentations and emerging themes. Copyright © 2017 American Society for Microbiology.

  11. 76 FR 70709 - Sunshine Act Meeting; Emergency Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meeting; Emergency Meeting Notice This notice that an emergency meeting was held is published pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, 5 U.S.C. 552b. AGENCY HOLDING THE MEETING: Commodity Futures Trading...

  12. Children's drawings of an anxiety-eliciting topic: effects on the size of the drawing.

    PubMed

    Fox, T J; Thomas, G V

    1990-02-01

    Our aim was to investigate whether or not children's drawings of a potentially threatening topic (a Hallowe'en witch) were made significantly smaller than drawings of a non-threatening topic (a woman). The first study confirmed an earlier claim by Craddick (1963) that drawings of a witch were made significantly smaller on the day before Hallowe'en compared to drawings made one week before or after, but we found that drawings of a non-threatening topic (a woman) changed in size in exactly the same way. Furthermore, we found no evidence that children became significantly more frightened of witches as Hallowe'en approached. In the second study, questionnaire responses were used to allocate children into two groups, those who were scared of witches and those who were not. Scared children drew both smaller witches and larger women than did non-scared children, with the result that relative heights of witches compared to women differed significantly between the two groups. However, only the difference in the height of the drawings of a woman was statistically significant. The implications of these results for the clinical assessment of children through their drawings are discussed.

  13. Mission Status at Aura Science Team MOWG Meeting: EOS Aura

    NASA Technical Reports Server (NTRS)

    Fisher, Dominic

    2016-01-01

    Presentation at the 24797-16 Earth Observing System (EOS) Aura Science Team Meeting (Mission Operations Work Group (MOWG)) at Rotterdam, Netherlands August 29, 2016. Presentation topics include mission summary, spacecraft subsystems summary, recent and planned activities, spacecraft anomalies, data capture, propellant usage and lifetime estimates, spacecraft maneuvers and ground track history, mission highlights and past spacecraft anomalies and reliability estimates.

  14. Beyond Seed and Soil: Understanding and Targeting Metastatic Prostate Cancer; Report From the 2016 Coffey-Holden Prostate Cancer Academy Meeting.

    PubMed

    Miyahira, Andrea K; Roychowdhury, Sameek; Goswami, Sangeeta; Ippolito, Joseph E; Priceman, Saul J; Pritchard, Colin C; Sfanos, Karen S; Subudhi, Sumit K; Simons, Jonathan W; Pienta, Kenneth J; Soule, Howard R

    2017-02-01

    The 2016 Coffey-Holden Prostate Cancer Academy (CHPCA) Meeting, "Beyond Seed and Soil: Understanding and Targeting Metastatic Prostate Cancer," was held from June 23 to June 26, 2016, in Coronado, California. For the 4th year in a row, the Prostate Cancer Foundation (PCF) hosted the CHPCA Meeting, a think tank-structured scientific conference, which focuses on a specific topic of critical unmet need on the biology and treatment of advanced prostate cancer. The 2016 CHPCA Meeting was attended by 71 investigators from prostate cancer and other fields, who discussed the biology, study methodologies, treatment strategies, and critical unmet needs concerning metastatic prostate cancer, with the ultimate goal of advancing strategies to treat and eliminate this disease. The major topics of discussion included: the molecular landscape and molecular heterogeneity of metastatic prostate cancer, the role of the metastatic microenvironment, optimizing immunotherapy in metastatic prostate cancer, learning from exceptional responders and non-responders, targeting DNA repair deficiency in advanced prostate cancer, developing and applying novel biomarkers and imaging techniques, and potential roles for the microbiome in prostate cancer. This article reviews the topics presented and discussions held at the CHPCA Meeting, with a focus on the unknowns and next steps needed to advance our understanding of the biology and most effective treatment strategies for metastatic prostate cancer. Prostate 77:123-144, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  15. Proceedings of the Twentieth International Microgravity Measurements Group Meeting

    NASA Technical Reports Server (NTRS)

    DeLombard, Richard (Compiler)

    2001-01-01

    The International Microgravity Measurements Group annual meetings provide a forum for an exchange of information and ideas about various aspects of microgravity acceleration research in international microgravity research programs. These meetings are sponsored by the PI Microgravity Services (PIMS) project at the NASA Glenn Research Center. The twentieth MGMG meeting was held 7-9 August 2001 at the Hilton Garden Inn Hotel in Cleveland, Ohio. The 35 attendees represented NASA, other space agencies, universities, and commercial companies; eight of the attendees were international representatives from Canada, Germany, Italy, Japan, and Russia. Seventeen presentations were made on a variety of microgravity environment topics including the International Space Station (ISS), acceleration measurement and analysis results, science effects from microgravity accelerations, vibration isolation, free flyer satellites, ground testing, and microgravity outreach. Two working sessions were included in which a demonstration of ISS acceleration data processing and analyses were performed with audience participation. Contained within the minutes is the conference agenda which indicates each speaker, the title of their presentation, and the actual time of their presentation. The minutes also include the charts for each presentation which indicate the author's name(s) and affiliation. In some cases, a separate written report was submitted and has been included here.

  16. Topic Maps: Adopting User-Centred Indexing Technologies in Course Management Systems

    ERIC Educational Resources Information Center

    Venkatesh, Vivek; Shaw, Steven; Dicks, Dennis; Lowerison, Gretchen; Zhang, Dai; Sanjakdar, Roukana

    2007-01-01

    This article provides an empirical evaluation of an indexing technology, topic maps (ISO 13250), in the context of an academic task in a higher education context. Topic maps are a form of indexing that define and display the interrelationships between various topics in a given domain, as well as anchor these topics to specific resources that help…

  17. Polluted online information? Surfing Italian websites dealing with the topic of waste and health

    NASA Astrophysics Data System (ADS)

    Orizio, G.; Locatelli, M. K.; Caimi, L.; Gelatti, U.

    2011-10-01

    In the field of health communication, a particularly critical issue is communication to the public of environmental risks, especially on topics for which there is still a high degree of scientific uncertainty regarding risk estimates. One such topic is undoubtedly the impact of waste on people's health. The aim of this study was to evaluate the presence and characteristics of Italian websites dealing with the topic of waste and health. The keywords 'waste' and 'health' were entered in 2010 in the three most commonly used search engines, and the first five pages were analysed. The selected websites were coded according to the content analysis method. For websites of interest we evaluated the 'page rank'. Out of the 150 occurrences analysed, the number of websites found to deal with this subject was only 19, four of which were of an institutional nature. The majority of websites gave a message of increased health risk associated with the three kinds of waste disposal tackled. As regards visibility, only one of the four institutional websites maintained its position on the first page of the three search engines. We found that institutional health websites have low visibility, despite extensive media coverage of waste and health issues in Italy as a result of the Naples case, which was debated globally. This indicates that public health institutions' web strategies are basically unable to meet people's health information requirements, which could strengthen rival health information providers.

  18. Adverse Effects (AEs) of Topical NSAIDs in Older Adults with Osteoarthritis (OA): a Systematic Review of the Literature

    PubMed Central

    Makris, UE.; Kohler, MJ.; Fraenkel, L.

    2010-01-01

    Objective To systematically review the literature on reported adverse effects (AEs) associated with topical NSAID use in older adults with osteoarthritis (OA). Methods A systematic search of Medline (1950 to November 2009), Scopus, Embase, Web of Science, Cochrane databases, Dissertation and American College of Rheumatology Meeting Abstracts was performed to identify original randomized controlled trials, case reports, observational studies, editorials or dissertations reporting AEs from topical NSAIDs in older adults with OA. Information was sought on study and participant characteristics, detailed recording of application site and systemic AEs as well as withdrawals due to AEs. Results The initial search yielded 953 articles of which 19 met eligibility criteria. Subjects receiving topical NSAIDs reported up to 39.3% application site AEs, and up to 17.5% systemic AEs. Five cases of warfarin potentiation with topical agents were reported; 1 resulting in gastrointestinal bleeding. In formal trials, the withdrawal rate from AEs ranged from 0-21% in the topical agents, 0-25% in the oral NSAIDs, and 0-16% in the placebo group. Conclusion In summary, although topical NSAIDs are safer than oral NSAIDs (fewer severe gastrointestinal AEs), a substantial proportion of older adults report systemic AEs with topical agents. Moreover, the withdrawal rate due to AEs with topical agents is comparable to that of oral NSAIDs. Given the safety profile and withdrawal rates described in this study, further data are needed to determine the incremental benefits of topical NSAIDs compared to other treatment modalities in older adults with OA. PMID:20360183

  19. Meeting the Needs of Travel Clientele: Tried and True Strategies That Work.

    ERIC Educational Resources Information Center

    Blessing, Kathy; Whitney, Cherine

    This paper describes sources for meeting the information needs of travel clientele. Topics addressed include: (1) U.S. government Web sites; (2) collection development tools, including review journals, online bookstores, travel Web sites, and sources of point-by-point comparisons of guide books; (3) prominent guidebook series and publisher Web…

  20. Topical hyperbaric oxygen and electrical stimulation: exploring potential synergy.

    PubMed

    Edsberg, Laura E; Brogan, Michael S; Jaynes, C David; Fries, Kristin

    2002-11-01

    Treatment of chronic wounds involves interventions ranging from dressings to surgery. Modalities gaining popularity in clinical settings include topical hyperbaric oxygen and electrical stimulation. A prospective, uncontrolled study was conducted to obtain preliminary observations and data about the effects of topical hyperbaric oxygen therapy and topical hyperbaric oxygen used with electrical stimulation on the healing of chronic wounds. All subjects were geriatric residents of long-term care facilities with Stage III or Stage IV pressure ulcers. Topical hyperbaric oxygen was applied daily to the wounds of eight subjects; three also received electrical stimulation. Initial wound size ranged from 87.75 cm2 to 7.04 cm2 with an average size of 30.1 +/- 28.5 (mean +/- sd) cm2. Healing times ranged from 8 to 49 weeks. After 4 weeks of treatment with topical hyperbaric oxygen, wound size decreased an average of 34.4% +/- 22.9%. Incidentally, the wounds of five of the eight subjects decreased more than 20%, for an average of 51.8% +/- 17.9%. No significant differences in healing were observed between patients receiving topical hyperbaric oxygen alone and those receiving topical hyperbaric oxygen/electrical stimulation. Preliminary data indicate that topical hyperbaric oxygen facilitates wound healing and full closure for pressure ulcers in patients with and without diabetes mellitus. A multicenter, prospective, randomized, double-blind controlled study is currently under way.

  1. Remote sensing of atmosphere and oceans; Proceedings of Symposium 1 and of the Topical Meeting of the 27th COSPAR Plenary Meeting, Espoo, Finland, July 18-29, 1988

    NASA Technical Reports Server (NTRS)

    Raschke, E. (Editor); Ghazi, A. (Editor); Gower, J. F. R. (Editor); Mccormick, P. (Editor); Gruber, A. (Editor); Hasler, A. F. (Editor)

    1989-01-01

    Papers are presented on the contribution of space remote sensing observations to the World Climate Research Program and the Global Change Program, covering topics such as space observations for global environmental monitoring, experiments related to land surface fluxes, studies of atmospheric composition, structure, motions, and precipitation, and remote sensing for oceanography, observational studies of the atmosphere, clouds, and the earth radiation budget. Also, papers are given on results from space observations for meteorology, oceanography, and mesoscale atmospheric and ocean processes. The topics include vertical atmospheric soundings, surface water temperature determination, sea level variability, data on the prehurricane atmosphere, linear and circular mesoscale convective systems, Karman vortex clouds, and temporal patterns of phytoplankton abundance.

  2. Topical treatment of melasma.

    PubMed

    Bandyopadhyay, Debabrata

    2009-01-01

    Melasma is a common hypermelanotic disorder affecting the face that is associated with considerable psychological impacts. The management of melasma is challenging and requires a long-term treatment plan. In addition to avoidance of aggravating factors like oral pills and ultraviolet exposure, topical therapy has remained the mainstay of treatment. Multiple options for topical treatment are available, of which hydroquinone (HQ) is the most commonly prescribed agent. Besides HQ, other topical agents for which varying degrees of evidence for clinical efficacy exist include azelaic acid, kojic acid, retinoids, topical steroids, glycolic acid, mequinol, and arbutin. Topical medications modify various stages of melanogenesis, the most common mode of action being inhibition of the enzyme, tyrosinase. Combination therapy is the preferred mode of treatment for the synergism and reduction of untoward effects. The most popular combination consists of HQ, a topical steroid, and retinoic acid. Prolonged HQ usage may lead to untoward effects like depigmentation and exogenous ochronosis. The search for safer alternatives has given rise to the development of many newer agents, several of them from natural sources. Well-designed controlled clinical trials are needed to clarify their role in the routine management of melasma.

  3. TOPICAL TREATMENT OF MELASMA

    PubMed Central

    Bandyopadhyay, Debabrata

    2009-01-01

    Melasma is a common hypermelanotic disorder affecting the face that is associated with considerable psychological impacts. The management of melasma is challenging and requires a long-term treatment plan. In addition to avoidance of aggravating factors like oral pills and ultraviolet exposure, topical therapy has remained the mainstay of treatment. Multiple options for topical treatment are available, of which hydroquinone (HQ) is the most commonly prescribed agent. Besides HQ, other topical agents for which varying degrees of evidence for clinical efficacy exist include azelaic acid, kojic acid, retinoids, topical steroids, glycolic acid, mequinol, and arbutin. Topical medications modify various stages of melanogenesis, the most common mode of action being inhibition of the enzyme, tyrosinase. Combination therapy is the preferred mode of treatment for the synergism and reduction of untoward effects. The most popular combination consists of HQ, a topical steroid, and retinoic acid. Prolonged HQ usage may lead to untoward effects like depigmentation and exogenous ochronosis. The search for safer alternatives has given rise to the development of many newer agents, several of them from natural sources. Well-designed controlled clinical trials are needed to clarify their role in the routine management of melasma. PMID:20101327

  4. Writing Abstracts and Developing Posters for National Meetings

    PubMed Central

    Morrison, R. Sean

    2011-01-01

    Abstract Presenting posters at national meetings can help fellows and junior faculty members develop a national reputation. They often lead to interesting and fruitful networking and collaboration opportunities. They also help with promotion in academic medicine and can reveal new job opportunities. Practically, presenting posters can help justify funding to attend a meeting. Finally, this process can be invaluable in assisting with manuscript preparation. This article provides suggestions and words of wisdom for palliative care fellows and junior faculty members wanting to present a poster at a national meeting describing a case study or original research. It outlines how to pick a topic, decide on collaborators, and choose a meeting for the submission. It also describes how to write the abstract using examples that present a general format as well as writing tips for each section. It then describes how to prepare the poster and do the presentation. Sample poster formats are provided as are talking points to help the reader productively interact with those that visit the poster. Finally, tips are given regarding what to do after the meeting. The article seeks to not only describe the basic steps of this entire process, but also to highlight the hidden curriculum behind the successful abstracts and posters. These tricks of the trade can help the submission stand out and will make sure the reader gets the most out of the hard work that goes into a poster presentation at a national meeting. PMID:21241194

  5. Writing abstracts and developing posters for national meetings.

    PubMed

    Wood, Gordon J; Morrison, R Sean

    2011-03-01

    Presenting posters at national meetings can help fellows and junior faculty members develop a national reputation. They often lead to interesting and fruitful networking and collaboration opportunities. They also help with promotion in academic medicine and can reveal new job opportunities. Practically, presenting posters can help justify funding to attend a meeting. Finally, this process can be invaluable in assisting with manuscript preparation. This article provides suggestions and words of wisdom for palliative care fellows and junior faculty members wanting to present a poster at a national meeting describing a case study or original research. It outlines how to pick a topic, decide on collaborators, and choose a meeting for the submission. It also describes how to write the abstract using examples that present a general format as well as writing tips for each section. It then describes how to prepare the poster and do the presentation. Sample poster formats are provided as are talking points to help the reader productively interact with those that visit the poster. Finally, tips are given regarding what to do after the meeting. The article seeks to not only describe the basic steps of this entire process, but also to highlight the hidden curriculum behind the successful abstracts and posters. These tricks of the trade can help the submission stand out and will make sure the reader gets the most out of the hard work that goes into a poster presentation at a national meeting.

  6. 75 FR 69701 - Notice of Public Meeting, John Day/Snake Resource Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-15

    ... conduct a public meeting to discuss several topics, including the Blue Mountain Forest Plan Revision..., Pendleton, Oregon 97801. For a copy of material to be discussed or the conference call number, please..., Oregon 97754, (541) 416-6889 or e-mail: [email protected] . Stephen R. Robertson, Associate...

  7. Image Re-Ranking Based on Topic Diversity.

    PubMed

    Qian, Xueming; Lu, Dan; Wang, Yaxiong; Zhu, Li; Tang, Yuan Yan; Wang, Meng

    2017-08-01

    Social media sharing Websites allow users to annotate images with free tags, which significantly contribute to the development of the web image retrieval. Tag-based image search is an important method to find images shared by users in social networks. However, how to make the top ranked result relevant and with diversity is challenging. In this paper, we propose a topic diverse ranking approach for tag-based image retrieval with the consideration of promoting the topic coverage performance. First, we construct a tag graph based on the similarity between each tag. Then, the community detection method is conducted to mine the topic community of each tag. After that, inter-community and intra-community ranking are introduced to obtain the final retrieved results. In the inter-community ranking process, an adaptive random walk model is employed to rank the community based on the multi-information of each topic community. Besides, we build an inverted index structure for images to accelerate the searching process. Experimental results on Flickr data set and NUS-Wide data sets show the effectiveness of the proposed approach.

  8. The 23rd Annual Meeting of the European Tissue Repair Society (ETRS) in Reims, France

    PubMed Central

    2014-01-01

    The 23rd Annual Meeting of the European Tissue Repair Society, Reims, France, October 23 to 25, 2013 focused on tissue repair and regenerative medicine covering topics such as stem cells, biomaterials, tissue engineering, and burns. PMID:24552134

  9. 76 FR 59395 - Notice of Webcast Meeting of the Environmental Financial Advisory Board (EFAB)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... creative approaches to funding environmental programs, projects, and activities. The purpose of the meeting... priorities and to discuss progress with work projects under EFAB's current Strategic Action Agenda; and... topics expected to be discussed include: financing clean air technology; financing tribal environmental...

  10. 76 FR 7844 - Notice of Open Meeting of the Environmental Financial Advisory Board (EFAB)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... environmental programs, projects, and activities. The purpose of the meeting is to hear from informed speakers... work projects under EFAB's current Strategic Action Agenda. Environmental Finance topics expected to be discussed include: Financing Clean Air Technology; Voluntary Environmental Improvement Bonds (VEIB)/Property...

  11. Workshops of the Fifth International Brain-Computer Interface Meeting: Defining the Future

    PubMed Central

    Huggins, Jane E.; Guger, Christoph; Allison, Brendan; Anderson, Charles W.; Batista, Aaron; Brouwer, Anne-Marie (A.-M.); Brunner, Clemens; Chavarriaga, Ricardo; Fried-Oken, Melanie; Gunduz, Aysegul; Gupta, Disha; Kübler, Andrea; Leeb, Robert; Lotte, Fabien; Miller, Lee E.; Müller-Putz, Gernot; Rutkowski, Tomasz; Tangermann, Michael; Thompson, David Edward

    2014-01-01

    The Fifth International Brain-Computer Interface (BCI) Meeting met June 3–7th, 2013 at the Asilomar Conference Grounds, Pacific Grove, California. The conference included 19 workshops covering topics in brain-computer interface and brain-machine interface research. Topics included translation of BCIs into clinical use, standardization and certification, types of brain activity to use for BCI, recording methods, the effects of plasticity, special interest topics in BCIs applications, and future BCI directions. BCI research is well established and transitioning to practical use to benefit people with physical impairments. At the same time, new applications are being explored, both for people with physical impairments and beyond. Here we provide summaries of each workshop, illustrating the breadth and depth of BCI research and high-lighting important issues for future research and development. PMID:25485284

  12. Workshops of the Fifth International Brain-Computer Interface Meeting: Defining the Future.

    PubMed

    Huggins, Jane E; Guger, Christoph; Allison, Brendan; Anderson, Charles W; Batista, Aaron; Brouwer, Anne-Marie A-M; Brunner, Clemens; Chavarriaga, Ricardo; Fried-Oken, Melanie; Gunduz, Aysegul; Gupta, Disha; Kübler, Andrea; Leeb, Robert; Lotte, Fabien; Miller, Lee E; Müller-Putz, Gernot; Rutkowski, Tomasz; Tangermann, Michael; Thompson, David Edward

    2014-01-01

    The Fifth International Brain-Computer Interface (BCI) Meeting met June 3-7 th , 2013 at the Asilomar Conference Grounds, Pacific Grove, California. The conference included 19 workshops covering topics in brain-computer interface and brain-machine interface research. Topics included translation of BCIs into clinical use, standardization and certification, types of brain activity to use for BCI, recording methods, the effects of plasticity, special interest topics in BCIs applications, and future BCI directions. BCI research is well established and transitioning to practical use to benefit people with physical impairments. At the same time, new applications are being explored, both for people with physical impairments and beyond. Here we provide summaries of each workshop, illustrating the breadth and depth of BCI research and high-lighting important issues for future research and development.

  13. Exploring supervised and unsupervised methods to detect topics in biomedical text

    PubMed Central

    Lee, Minsuk; Wang, Weiqing; Yu, Hong

    2006-01-01

    Background Topic detection is a task that automatically identifies topics (e.g., "biochemistry" and "protein structure") in scientific articles based on information content. Topic detection will benefit many other natural language processing tasks including information retrieval, text summarization and question answering; and is a necessary step towards the building of an information system that provides an efficient way for biologists to seek information from an ocean of literature. Results We have explored the methods of Topic Spotting, a task of text categorization that applies the supervised machine-learning technique naïve Bayes to assign automatically a document into one or more predefined topics; and Topic Clustering, which apply unsupervised hierarchical clustering algorithms to aggregate documents into clusters such that each cluster represents a topic. We have applied our methods to detect topics of more than fifteen thousand of articles that represent over sixteen thousand entries in the Online Mendelian Inheritance in Man (OMIM) database. We have explored bag of words as the features. Additionally, we have explored semantic features; namely, the Medical Subject Headings (MeSH) that are assigned to the MEDLINE records, and the Unified Medical Language System (UMLS) semantic types that correspond to the MeSH terms, in addition to bag of words, to facilitate the tasks of topic detection. Our results indicate that incorporating the MeSH terms and the UMLS semantic types as additional features enhances the performance of topic detection and the naïve Bayes has the highest accuracy, 66.4%, for predicting the topic of an OMIM article as one of the total twenty-five topics. Conclusion Our results indicate that the supervised topic spotting methods outperformed the unsupervised topic clustering; on the other hand, the unsupervised topic clustering methods have the advantages of being robust and applicable in real world settings. PMID:16539745

  14. Current Topics in Postnatal Behavioral Testing.

    PubMed

    Henck, Judith W; Elayan, Ikram; Vorhees, Charles; Fisher, J Edward; Morford, LaRonda L

    2016-09-01

    The study of developmental neurotoxicity (DNT) continues to be an important component of safety evaluation of candidate therapeutic agents and of industrial and environmental chemicals. Developmental neurotoxicity is considered to be an adverse change in the central and/or peripheral nervous system during development of an organism and has been primarily evaluated by studying functional outcomes, such as changes in behavior, neuropathology, neurochemistry, and/or neurophysiology. Neurobehavioral evaluations are a component of a wide range of toxicology studies in laboratory animal models, whereas neurochemistry and neurophysiology are less commonly employed. Although the primary focus of this article is on neurobehavioral evaluation in pre- and postnatal development and juvenile toxicology studies used in pharmaceutical development, concepts may also apply to adult nonclinical safety studies and Environmental Protection Agency/chemical assessments. This article summarizes the proceedings of a symposium held during the 2015 American College of Toxicology annual meeting and includes a discussion of the current status of DNT testing as well as potential issues and recommendations. Topics include the regulatory context for DNT testing; study design and interpretation; behavioral test selection, including a comparison of core learning and memory systems; age of testing; repeated testing of the same animals; use of alternative animal models; impact of findings; and extrapolation of animal results to humans. Integration of the regulatory experience and scientific concepts presented during this symposium, as well as from subsequent discussion and input, provides a synopsis of the current state of DNT testing in safety assessment, as well as a potential roadmap for future advancement. © The Author(s) 2016.

  15. Topical anesthesia for penetrating trabeculectomy.

    PubMed

    Sauder, Gangolf; Jonas, Jost B

    2002-09-01

    To evaluate the efficacy and clinical practicability of topical anesthesia in comparison with retrobulbar anesthesia for penetrating trabeculectomy. The prospective single-surgeon clinical interventional trial included 20 consecutive patients, who were randomly distributed into a topical anesthesia group ( n=10) and a retrobulbar anesthesia group ( n=10). In the topical anesthesia group, patients received preoperatively oxybuprocaine 0.4% eye drops and cocaine hydrochloride eye drops 10%. The patients of the retrobulbar group received 5 ml mepivacaine 2% injected into the retrobulbar space. To assess intraoperative pain, each patient was asked immediately after surgery to quantitate his/her pain using a 10-point pain rating scale. The topical anesthesia group and the retrobulbar anesthesia study group did not vary significantly in duration of surgery (21.5+/-3.37 min vs 20.2+/-4.46 min, P=0.31), preoperative intraocular pressure (32.2+/-14.62 mmHg vs 30.6+/-12.33 mmHg, P=0.22), postoperative intraocular pressure (8.0+/-4.47 mmHg vs 9.12+/-3.13 mmHg, P=0.64), subjective pain score by the patient (2.25+/-1.23 relative units vs 2.33+/-1.08 relative units ( P= 0.71), and practicability score by the surgeon (2.24+/-1.76 vs 2.56+/-1.58, P=0.82). In view of its clinical feasibility and its minimally invasive character, topical anesthesia may be an option for penetrating trabeculectomy.

  16. An Analysis of the Most Commonly Tested Topics and Their Taxonomy From Recent Self-Assessment Examinations.

    PubMed

    Krueger, Chad A; Moroze, Sean; Murtha, Andrew S; Rivera, Jessica C

    The purpose of this study is to determine the most commonly tested topics and the question taxonomy of the American Academy of Orthopaedic Surgeons Self-Assessment Examinations (SAE) from 2009 through 2014. All SAEs were analyzed from 2009 through 2014. The SAEs were separated by subject and the questions of each SAE were analyzed for topic, taxonomic classification, and question type. A total of 2107 questions were reviewed from 10 different subjects. In all, 6 of the 9 subjects had roughly 1/3 of their questions composed of the 3 most commonly tested topics. Each subject had at least 1 trauma-related question within its top 5 most commonly tested topics. Almost half (47%) of all questions were of taxonomy 1 classification and 29% were taxonomy 3. The Basic Science SAEs had the greatest percentage of taxonomy 1 questions of any subject (83%) whereas Trauma contained the highest percentage of taxonomy 3 questions (47%). Certain topics within each subject are consistently tested more often than other topics. In general, the 3 most commonly tested topics comprise about one-third of total questions and orthopedic surgeons should be very familiar with these topics in order to best prepare for standardized examinations. Published by Elsevier Inc.

  17. Meeting report from the fourth meeting of the Computational Modeling in Biology Network (COMBINE)

    PubMed Central

    Waltemath, Dagmar; Bergmann, Frank T.; Chaouiya, Claudine; Czauderna, Tobias; Gleeson, Padraig; Goble, Carole; Golebiewski, Martin; Hucka, Michael; Juty, Nick; Krebs, Olga; Le Novère, Nicolas; Mi, Huaiyu; Moraru, Ion I.; Myers, Chris J.; Nickerson, David; Olivier, Brett G.; Rodriguez, Nicolas; Schreiber, Falk; Smith, Lucian; Zhang, Fengkai; Bonnet, Eric

    2014-01-01

    The Computational Modeling in Biology Network (COMBINE) is an initiative to coordinate the development of community standards and formats in computational systems biology and related fields. This report summarizes the topics and activities of the fourth edition of the annual COMBINE meeting, held in Paris during September 16-20 2013, and attended by a total of 96 people. This edition pioneered a first day devoted to modeling approaches in biology, which attracted a broad audience of scientists thanks to a panel of renowned speakers. During subsequent days, discussions were held on many subjects including the introduction of new features in the various COMBINE standards, new software tools that use the standards, and outreach efforts. Significant emphasis went into work on extensions of the SBML format, and also into community-building. This year’s edition once again demonstrated that the COMBINE community is thriving, and still manages to help coordinate activities between different standards in computational systems biology.

  18. Topics

    ERIC Educational Resources Information Center

    Mathematics Teaching, 1972

    1972-01-01

    Topics discussed in this column include patterns of inverse multipliers in modular arithmetic; diagrams for product sets, set intersection, and set union; function notation; patterns in the number of partitions of positive integers; and tessellations. (DT)

  19. Exploring the role and function of trial steering committees: results of an expert panel meeting.

    PubMed

    Harman, Nicola L; Conroy, Elizabeth J; Lewis, Steff C; Murray, Gordon; Norrie, John; Sydes, Matt R; Lane, J Athene; Altman, Douglas G; Baigent, Colin; Bliss, Judith M; Campbell, Marion K; Elbourne, Diana; Evans, Stephen; Sandercock, Peter; Gamble, Carrol

    2015-12-30

    The independent oversight of clinical trials, which is recommended by the Medical Research Council (MRC) Guidelines for Good Clinical Practice, is typically provided by an independent advisory Data Monitoring Committee (DMC) and an independent executive committee, to whom the DMC makes recommendations. The detailed roles and function of this executive committee, known as the Trial Steering Committee (TSC), have not previously been studied or reviewed since those originally proposed by the MRC in 1998. An expert panel (n = 7) was convened comprising statisticians, clinicians and trial methodologists with prior TSC experience. Twelve questions about the role and responsibilities of the TSC were discussed by the panel at two full-day meetings. Each meeting was transcribed in full and the discussions were summarised. The expert panel reached agreement on the role of the TSC, to which it was accountable, the membership, the definition of independence, and the experience and training needed. The management of ethical issues, difficult/complex situations and issues the TSC should not ask the DMC to make recommendations on were more difficult to discuss without specific examples, but support existed for further work to help share issues and to provide appropriate training for TSC members. Additional topics discussed, which had not been identified by previous work relating to the DMCs but were pertinent to the role of the TSC, included the following: review of data sharing requests, indemnity, lifespan of the TSC, general TSC administration, and the roles of both the Funder and the Sponsor. This paper presents recommendations that will contribute to the revision and update of the MRC TSC terms of reference. Uncertainty remains in some areas due to the absence of real-life examples; future guidance on these issues would benefit from a repository of case studies. Notably, the role of a patient and public involvement (PPI) contributor was not discussed, and further work is

  20. Proceedings of the 50th Anniversary Meeting, National Association of Schools of Music.

    ERIC Educational Resources Information Center

    National Association of Schools of Music, Reston, VA.

    Special remarks, reports, and presentations from the anniversary meeting are offered. Topics covered include: advice to students and teachers; teaching in hard times; the arts and the campus; esthetic education: dialogue about the musical experience; affirmative action; the Greek connection; the 31-note equal tuning of Nicola Vincentino;…

  1. Topical Administration of Oxygenated Hemoglobin Improved Wound Healing in an Ischemic Rabbit Ear Model.

    PubMed

    Xie, Ping; Jia, Shengxian; Tye, Ross; Xu, Wei; Zhong, Aimei; Hong, Seok J; Galiano, Robert D; Mustoe, Thomas A

    2016-02-01

    Localized oxygen deficiency plays a central role in the pathogenesis of chronic wounds; thus, rectifying localized ischemia with oxygen therapy has been postulated to be an integral aspect of the management of chronic wounds. The efficacy of a novel approach for oxygen therapy on chronic wound healing was evaluated. Oxygen was delivered to ischemic wounds by means of the topical application of oxygenated, chemically modified bovine hemoglobin (IKOR 2084) in a validated rabbit ear ischemic wound model. The wound healing was evaluated histologically by measuring epithelial gap and neo-granulation tissue area. In situ expression of endothelial cells (CD31) and proliferative cells (Ki-67) was examined by immunohistochemistry analysis. The mRNA of vascular endothelial growth factor, endothelial nitric oxide synthase, and matrix metalloproteinase-9 was quantified by real-time reverse-transcriptase polymerase chain reaction. The collagen was detected by Sirius red staining. In comparison with topical application of saline, the administration of oxygenated IKOR 2084 increases wound reepithelialization and formation of neo-granulation tissue in a dose-dependent manner, and cellular proliferation (Ki-67). Conversely, the administration of deoxygenated IKOR 2084 aggravated the ischemic wound healing process. Moreover, the topical administration of oxygenated IKOR 2084 induces angiogenesis as evidenced by concomitant increases in CD31 protein and vascular endothelial growth factor and endothelial nitric oxide synthase mRNA expression in treated wounds. Oxygenated IKOR 2084 administration also increased collagen deposition in wounds, with decreases in the expression of matrix metalloproteinase-9 mRNA. This study suggests that the topical application of oxygenated IKOR 2084 ameliorates the reparative progress of ischemic wounds through enhanced angiogenesis, cellular proliferation, and collagen deposition.

  2. JANNAF 35th Combustion Subcommittee and 17th Propulsion Systems Hazards Subcommittee Meeting: Joint Sessions

    NASA Technical Reports Server (NTRS)

    Fry, Ronald S. (Editor); Gannaway, Mary T. (Editor); Rognan, Melanie (Editor)

    1998-01-01

    This publication is a compilation of 15 unclassified/unlimited technical papers presented at the 1998 meeting of the Joint Army-Navy-NASA-Air Force (JANNAF) Combustion Subcommittee (CS) and Propulsion Systems Hazards Subcommittee (PSHS) held jointly with the Airbreathing Propulsion Subcommittee (APS). The meeting was held on 7 - 11 December 1 998 at Raytheon Systems Company and the Marriott Hotel, Tucson, AZ. Topics covered include advanced ingredients and reaction kinetics in solid propellants and experimental diagnostic techniques.

  3. Readability and quality of wikipedia pages on neurosurgical topics.

    PubMed

    Modiri, Omeed; Guha, Daipayan; Alotaibi, Naif M; Ibrahim, George M; Lipsman, Nir; Fallah, Aria

    2018-03-01

    Wikipedia is the largest online encyclopedia with over 40 million articles, and generating 500 million visits per month. The aim of this study is to assess the readability and quality of Wikipedia pages on neurosurgical related topics. We selected the neurosurgical related Wikipedia pages based on the series of online patient information articles that are published by the American Association of Neurological Surgeons (AANS). We assessed readability of Wikipedia pages using five different readability scales (Flesch Reading Ease, Flesch Kincaid Grade Level, Gunning Fog Index, SMOG) Grade level, and Coleman-Liau Index). We used the Center for Disease Control (CDC) Clear Communication Index as well as the DISCERN Instrument to evaluate the quality of each Wikipedia article. We identified a total of fifty-five Wikipedia articles that corresponded with patient information articles published by the AANS. This constitutes 77.46% of the AANS topics. The mean Flesch Kincaid reading ease score for all of the Wikipedia articles we analyzed is 31.10, which indicates that a college-level education is necessary to understand them. In comparison to the readability analysis for the AANS articles, the Wikipedia articles were more difficult to read across every scale. None of the Wikipedia articles meet the CDC criterion for clear communications. Our analyses demonstrated that Wikipedia articles related to neurosurgical topics are associated with higher grade levels for reading and also below the expected levels of clear communications for patients. Collaborative efforts from the neurosurgical community are needed to enhance the readability and quality of Wikipedia pages related to neurosurgery. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. Topical dissolved oxygen penetrates skin: model and method.

    PubMed

    Roe, David F; Gibbins, Bruce L; Ladizinsky, Daniel A

    2010-03-01

    It has been commonly perceived that skin receives its oxygen supply from the internal circulation. However, recent investigations have shown that a significant amount of oxygen may enter skin from the external overlying surface. A method has been developed for measuring the transcutaneous penetration of human skin by oxygen as described herein. This method was used to determine both the depth and magnitude of penetration of skin by topically applied oxygen. An apparatus consisting of human skin samples interposed between a topical oxygen source and a fluid filled chamber that registered changes in dissolved oxygen. Viable human skin samples of variable thicknesses with and without epidermis were used to evaluate the depth and magnitude of oxygen penetration from either topical dissolved oxygen (TDO) or topical gaseous oxygen (TGO) devices. This model effectively demonstrates transcutaneous penetration of topically applied oxygen. Topically applied dissolved oxygen penetrates through >700 microm of human skin. Topically applied oxygen penetrates better though dermis than epidermis, and TDO devices deliver oxygen more effectively than TGO devices. Copyright (c) 2010 Elsevier Inc. All rights reserved.

  5. NEWS: AAPT Summer Meeting

    NASA Astrophysics Data System (ADS)

    Mellema, Steve

    2000-11-01

    .andrew.cmu.edu/projects/visual. David Sokoloff (University of Oregon) and Priscilla Laws (Dickinson College) led a discussion session on the Interactive Lecture Demonstrations that they have been developing to promote active learning in the classroom. Loren Winters of the North Carolina School of Science and Mathematics showed some very fine work done with digital video cameras, both in producing motion videos for frame-by-frame analysis and in producing still images of high-speed phenomena. Finally, Patrick Tam of Humboldt State University in California talked about the Multimedia Resource for Learning and Online Teaching (MERLOT), a project to organize and review the proliferation of internet-based teaching materials that are rapidly becoming available. Their purpose is to make it easier for teachers like us to sift through the plethora of new innovations, to locate those that are potentially useful in our teaching, and finally to implement them effectively. You can check out the project on the web at www.merlot.org. As is evident from the number of sessions of contributed papers and the tandem conference, the quality and quantity of physics education research into new curricula and teaching methods continue to increase. A number of interesting areas were discussed including interactive lecture techniques, studio-classroom approaches combining lectures and labs, assessment techniques, and identifying and correcting student misconceptions. In addition to the plenary talks on current research topics in physics mentioned above, there were sessions on Space Physics and Hot Topics in Physics. There were sessions on professional and career concerns including Preparing Future Physics Faculty, New Faculty Experiences and Concerns, Balancing Career and Family, How Physics Topics Support the Job Market and Recruiting and Retaining Women in Physics. Whether one was a high school teacher or a university professor, this was an enjoyable and educational meeting. We all look forward to the Winter 2001 meeting from

  6. Preliminary stop of the TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC) trial.

    PubMed

    Koeneman, M M; Kruse, A J; Kooreman, L F S; Zur Hausen, A; Hopman, A H N; Sep, S J S; Van Gorp, T; Slangen, B F M; van Beekhuizen, H J; van de Sande, A J M; Gerestein, C G; Nijman, H W; Kruitwagen, R F P M

    2017-02-07

    The "TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia" (TOPIC) trial was stopped preliminary, due to lagging inclusions. This study aimed to evaluate the treatment efficacy and clinical applicability of imiquimod 5% cream in high-grade cervical intraepithelial neoplasia (CIN). The lagging inclusions were mainly due to a strong patient preference for either of the two treatment modalities. This prompted us to initiate a new study on the same subject, with a non-randomized, open-label design: the 'TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC)-3' study. Original TOPIC-trial: Medical Ethics Committee approval number METC13231; ClinicalTrials.gov Identifier: NCT02329171, 22 December 2014. TOPIC-3 study: Medical Ethics Committee approval number METC162025; ClinicalTrials.gov Identifier: NCT02917746, 16 September 2016.

  7. Fostering Topic Knowledge: Essential for Academic Writing

    ERIC Educational Resources Information Center

    Proske, Antje; Kapp, Felix

    2013-01-01

    Several researchers emphasize the role of the writer's topic knowledge for writing. In academic writing topic knowledge is often constructed by studying source texts. One possibility to support that essential phase of the writing process is to provide interactive learning questions which facilitate the construction of an adequate situation…

  8. The human heart and the circulatory system as an interesting interdisciplinary topic in lessons of physics and biology

    NASA Astrophysics Data System (ADS)

    Volná, M.; Látal, F.; Kubínek, R.; Richterek, L.

    2014-01-01

    Many topics which are closely related can be found in the national curriculum of the Czech Republic for physics and biology. One of them is the heart and the circulatory system in the human body. This topic was examined cross curriculum, a teaching module was created and the topic was chosen for our research. The task was to determine if the students of bachelor study are aware of connections between physics and biology within this topic and whether we can help them effectively to describe the corresponding physics phenomena in the human body connected, for example, with a heart attack or with the measurement of blood pressure. In this paper, the heart and the circulatory system are presented as suitable topics for an interdisciplinary teaching module which includes both theoretical and experimental parts. The module was evaluated by a group of first-year undergraduate students of physics at the Faculty of Science, Palacký University. The acquired knowledge was compared with another control group through a test. The highest efficiency of the module was evaluated on the basis of questions that covered the calculation problems.

  9. "How Did We Get Here?": Topic Drift in Online Health Discussions.

    PubMed

    Park, Albert; Hartzler, Andrea L; Huh, Jina; Hsieh, Gary; McDonald, David W; Pratt, Wanda

    2016-11-02

    Patients increasingly use online health communities to exchange health information and peer support. During the progression of health discussions, a change of topic-topic drift-can occur. Topic drift is a frequent phenomenon linked to incoherence and frustration in online communities and other forms of computer-mediated communication. For sensitive topics, such as health, such drift could have life-altering repercussions, yet topic drift has not been studied in these contexts. Our goals were to understand topic drift in online health communities and then to develop and evaluate an automated approach to detect both topic drift and efforts of community members to counteract such drift. We manually analyzed 721 posts from 184 threads from 7 online health communities within WebMD to understand topic drift, members' reaction towards topic drift, and their efforts to counteract topic drift. Then, we developed an automated approach to detect topic drift and counteraction efforts. We detected topic drift by calculating cosine similarity between 229,156 posts from 37,805 threads and measuring change of cosine similarity scores from the threads' first posts to their sequential posts. Using a similar approach, we detected counteractions to topic drift in threads by focusing on the irregular increase of similarity scores compared to the previous post in threads. Finally, we evaluated the performance of our automated approaches to detect topic drift and counteracting efforts by using a manually developed gold standard. Our qualitative analyses revealed that in threads of online health communities, topics change gradually, but usually stay within the global frame of topics for the specific community. Members showed frustration when topic drift occurred in the middle of threads but reacted positively to off-topic stories shared as separate threads. Although all types of members helped to counteract topic drift, original posters provided the most effort to keep threads on topic

  10. A framework for conducting follow-up meetings with parents after a child's death in the pediatric intensive care unit*

    PubMed Central

    Eggly, Susan; Berger, John; Zimmerman, Jerry; Anand, Kanwaljeet J. S.; Newth, Christopher J. L.; Harrison, Rick; Carcillo, Joseph; Dean, J. Michael; Willson, Douglas F.; Nicholson, Carol

    2012-01-01

    Objective To describe a framework to assist pediatric intensive care unit physicians in conducting follow-up meetings with parents after their child's death. Many childhood deaths occur in pediatric intensive care units. Parents of children who die in pediatric intensive care units often desire a follow-up meeting with the physician(s) who cared for their child. Data Sources Prior research conducted by the Collaborative Pediatric Critical Care Research Network on the experiences and perspectives of bereaved parents and pediatric intensive care unit physicians regarding the desirability, content, and conditions of follow-up meetings. Results The framework includes suggestions for inviting families to follow-up meetings (i.e., developing an institutional system, invitation timing, and format); preparing for the meeting (i.e., assessing family preferences; determining location, attendees, and discussion topics; reviewing medical and psychosocial history); structure of the meeting (i.e., opening, closing, and developing a meeting agenda); communicating effectively during the meeting; and follow-up for both parents and physicians. Conclusion This framework is based on the experience and perspectives of bereaved parents and pediatric intensive care unit physicians. Future research should be conducted to determine the extent to which physician-parent follow-up meetings provide a benefit to parents, families, physicians, and other healthcare providers participating in these encounters. PMID:20625339

  11. A framework for conducting follow-up meetings with parents after a child's death in the pediatric intensive care unit.

    PubMed

    Eggly, Susan; Meert, Kathleen L; Berger, John; Zimmerman, Jerry; Anand, Kanwaljeet J S; Newth, Christopher J L; Harrison, Rick; Carcillo, Joseph; Dean, J Michael; Willson, Douglas F; Nicholson, Carol

    2011-03-01

    To describe a framework to assist pediatric intensive care unit physicians in conducting follow-up meetings with parents after their child's death. Many childhood deaths occur in pediatric intensive care units. Parents of children who die in pediatric intensive care units often desire a follow-up meeting with the physician(s) who cared for their child. Prior research conducted by the Collaborative Pediatric Critical Care Research Network on the experiences and perspectives of bereaved parents and pediatric intensive care unit physicians regarding the desirability, content, and conditions of follow-up meetings. The framework includes suggestions for inviting families to follow-up meetings (i.e., developing an institutional system, invitation timing, and format); preparing for the meeting (i.e., assessing family preferences; determining location, attendees, and discussion topics; reviewing medical and psychosocial history); structure of the meeting (i.e., opening, closing, and developing a meeting agenda); communicating effectively during the meeting; and follow-up for both parents and physicians. This framework is based on the experience and perspectives of bereaved parents and pediatric intensive care unit physicians. Future research should be conducted to determine the extent to which physician-parent follow-up meetings provide a benefit to parents, families, physicians, and other healthcare providers participating in these encounters.

  12. JANNAF Airbreathing Propulsion Subcommittee and 35th Combustion Subcommittee Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Fry, Ronald S. (Editor); Gannaway, Mary T. (Editor); Rognan, Melanie (Editor)

    1998-01-01

    This document, CPIA Publication 682, Volume 1, is a compilation of 5 unclassified/unlimited technical papers (approved for public release) which were presented at the 1 998 meeting of the Joint Army-Navy-NASA-Air Force (JANNAF) Airbreathing Propulsion Subcommittee (APS) and Combustion Subcommittee (CS) held jointly with the Propulsion Systems Hazards Subcommittee (PSHS). The meeting was held on 7-11 December 1998 at Raytheon Systems Company and the Marriott Hotel, Tucson, AZ. Topics covered include HyTech technology development, hydrocarbon fuel development for hypersonic applications, pulse detonation propulsion system development and arc heaters for direct-connect scramjet testing.

  13. Teaching Medication Compliance to Psychiatric Residents: Placing an Orphan Topic into a Training Curriculum

    ERIC Educational Resources Information Center

    Weiden, Peter J.; Rao, Nyapati

    2005-01-01

    OBJECTIVE: Medication compliance is an orphan topic. Training in the understanding and management of noncompliance does not neatly fall within the domain of psychopharmacology, nor does it clearly fit into other core curricula areas, such as clinical interviewing or psychotherapy training. The objective of this article is to increase awareness…

  14. JANNAF 17th Propulsion Systems Hazards Subcommittee Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Cocchiaro, James E. (Editor); Gannaway, Mary T. (Editor); Rognan, Melanie (Editor)

    1998-01-01

    Volume 1, the first of two volumes is a compilation of 16 unclassified/unlimited technical papers presented at the 17th meeting of the Joint Army-Navy-NASA-Air Force (JANNAF) Propulsion Systems Hazards Subcommittee (PSHS) held jointly with the 35th Combustion Subcommittee (CS) and Airbreathing Propulsion Subcommittee (APS). The meeting was held on 7 - 11 December 1998 at Raytheon Systems Company and the Marriott Hotel, Tucson, AZ. Topics covered include projectile and shaped charge jet impact vulnerability of munitions; thermal decomposition and cookoff behavior of energetic materials; damage and hot spot initiation mechanisms with energetic materials; detonation phenomena of solid energetic materials; and hazard classification, insensitive munitions, and propulsion systems safety.

  15. Meeting summary: A 2017 view of Active Galactic Nuclei

    NASA Astrophysics Data System (ADS)

    Netzer, Hagai

    2018-05-01

    The topics covered in this summary review reflect the major areas discussed in the Padova meeting, in April 2017. They are divided into general categories: those areas where large progress has been made leading to a real new understanding (what we are doing "right"), and those where we are still in the dark (what we are doing "wrong"). The division reflects the status of the field as well as my subjective opinion.

  16. Atopic dermatitis: a review of topical nonsteroid therapy.

    PubMed

    Papier, Ariana; Strowd, Lindsay C

    2018-01-01

    Atopic dermatitis is a chronic inflammatory skin condition that affects up to 20% of children and 3% of adults globally. Although topical corticosteroids are considered to be the first-line agents, they can be associated with cutaneous and systemic adverse effects. Since the early 2000s, two new classes of nonsteroid topical therapies, topical calcineurin inhibitors and phosphodiesterase 4 (PDE4) inhibitors, have been introduced and provide a safe treatment alternative. We performed a search and review of clinical trials that examined the safety and efficacy of topical calcineurin inhibitors and PDE4 inhibitors. The search was conducted using the PubMed database as well as preselected keywords and filters. This review focuses on the safety and efficacy of each therapy. Sixty-nine clinical trials identified in this study have demonstrated the efficacy and safety of topical calcineurin and a single novel PDE4 inhibitor in the treatment of atopic dermatitis. Topical calcineurin inhibitors have been shown to be effective in both achieving lesion clearance as well as reducing relapse when used long-term and proactively. Similarly, in clinical trials the PDE4 inhibitor showed success in lesion clearance and symptom management. All three therapies (pimecrolimus, tacrolimus, crisaborole) are associated with low systemic absorption. No clinical trials to date have shown an increased risk of systemic adverse events or malignancy such as lymphoma. The most commonly reported treatment-related adverse event across all three therapies was application-site discomfort, pain or pruritus. It is important to note that long-term studies are not yet available for the novel PDE4 inhibitor. Topical calcineurin inhibitors provide a safe and effective alternative to topical corticosteroid use in the treatment of atopic dermatitis. Although the US Food and Drug Administration (FDA) black box warning for topical calcineurin inhibitors remains, studies have not shown an increased risk of

  17. Regulatory Information By Topic

    EPA Pesticide Factsheets

    EPA develops and enforces regulations that span many environmental topics, from acid rain reduction to wetlands restoration. Each topic listed below may include related laws and regulations, compliance enforcement information, policies guidance

  18. 73rd American Welding Society annual meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-01-01

    The volume includes the abstracts of papers presented at the 73rd American Welding Society Annual Meeting. Detailed summaries are given for 118 technical sessions papers discussing computer and control applications in welding, stainless steel, nickel and nickel alloys, weld metal microstructure, shipbuilding, consumables, structural welding, investigations in arc welding and cutting, arc welding processes, weldability testing, piping and tubing, high energy beam welding processes, welding metallurgy of structural steels, new applications, weld metal behavior, NDT certification, aluminum welding, submerged arc welding, modeling studies, resistance welding, friction welding, and safety and health. The 23rd International AWS Brazing and Soldering Conference wasmore » also held during this meeting. The topics presented in 24 papers included recent developments in soldering technology, brazing of stainless steel, brazing of ceramics and nickel material, filler metal developments for torch brazing, and developments in diffusion and induction brazing.« less

  19. Coordinating Council. First Meeting: NASA/RECON database

    NASA Technical Reports Server (NTRS)

    1990-01-01

    A Council of NASA Headquarters, American Institute of Aeronautics and Astronautics (AIAA), and the NASA Scientific and Technical Information (STI) Facility management met (1) to review and discuss issues of NASA concern, and (2) to promote new and better ways to collect and disseminate scientific and technical information. Topics mentioned for study and discussion at subsequent meetings included the pros and cons of transferring the NASA/RECON database to the commercial sector, the quality of the database, and developing ways to increase foreign acquisitions. The input systems at AIAA and the STI Facility were described. Also discussed were the proposed RECON II retrieval system, the transmittal of document orders received by the Facility and sent to AIAA, and the handling of multimedia input by the Departments of Defense and Commerce. A second meeting was scheduled for six weeks later to discuss database quality and international foreign input.

  20. Anticipatory guidance topics: are more better?

    PubMed

    Barkin, Shari L; Scheindlin, Benjamin; Brown, Caroline; Ip, Edward; Finch, Stacia; Wasserman, Richard C

    2005-01-01

    Anticipatory guidance is a cornerstone of primary care pediatrics. Despite the fact that retention of information is essential for later action, data are lacking on what parents recall immediately after the visit and 1 month later and how the total number of topics discussed affects this outcome. Parents and practitioners completed postvisit surveys of anticipatory guidance topics discussed during health-maintenance visits for children ages 2-11. Postvisit and 1 month later, parental recall was compared with provider report of topics discussed. We examined the relationship between parental recall and the total number of topics discussed. Families with children ages 2-11 years from across the United States participated in this study (N = 861). Providers reported discussing the topics of nutrition, car restraints, dental care, and reading aloud most often (72%- 93%). Concordance between parent and provider was high for all topics (72%-90%). Immediately postvisit, parents reported 6.33 (SD 2.9) as the mean number of topics discussed while providers reported 6.9 (SD 2.7) as the mean number of topics discussed. However, parental recall decreased significantly with more topics (> or =9) discussed. The same trend existed 1 month later. Providers and parents have good agreement about topics discussed or not discussed during a well-child visit; however, parental recall dwindles with increasing numbers of topics discussed. Rethinking well-child care to limit the total number of topics discussed is warranted.

  1. “French Phage Network”—Second Meeting Report

    PubMed Central

    Torres-Barceló, Clara; Kaltz, Oliver; Froissart, Rémy; Gandon, Sylvain; Ginet, Nicolas; Ansaldi, Mireille

    2017-01-01

    The study of bacteriophages (viruses of bacteria) includes a variety of approaches, such as structural biology, genetics, ecology, and evolution, with increasingly important implications for therapeutic and industrial uses. Researchers working with phages in France have recently established a network to facilitate the exchange on complementary approaches, but also to engage new collaborations. Here, we provide a summary of the topics presented during the second meeting of the French Phage Network that took place in Marseille in November 2016. PMID:28430166

  2. Topical minoxidil fortified with finasteride: An account of maintenance of hair density after replacing oral finasteride.

    PubMed

    Chandrashekar, B S; Nandhini, T; Vasanth, Vani; Sriram, Rashmi; Navale, Shreya

    2015-01-01

    Finasteride acts by reducing dihydrotestosterone levels, thereby inhibiting miniaturization of hair follicles in patients with androgenetic alopecia (AGA). Oral finasteride is associated with side effects such as decreased libido, sexual dysfunction, and gynecomastia. The aim of the following study is to assess the efficacy of maintaining hair growth with 5% topical minoxidil fortified with 0.1% finasteride in patients with AGA after initial treatment with 5% topical minoxidil and oral finasteride for two years. A retrospective assessment was done in 50 male patients aged 20-40 years with AGA. All the patients had been initially treated with topical minoxidil and oral finasteride for a period of two years, after which the oral finasteride was replaced with topical minoxidil fortified with finasteride. Five of 50 patients had discontinued the treatment for a period of 8-12 months and were then resumed with only topical minoxidil fortified with finasteride. The patients' case sheets and photographs were reviewed by independent observers and the efficacy of minoxidil-finasteride combination was assessed. Of the 45 patients who underwent a continuous treatment for AGA, 84.44% maintained a good hair density with topical minoxidil-finasteride combinatio. Of the five patients who discontinued oral finasteride for 8-12 months, four demonstrated good improvement in hair density when treatment was resumed with topical minoxidil-finasteride combination. Topical finasteride can be considered for hair density maintenance after initial improvement with oral finasteride, thereby obviating the indefinite use of oral finasteride.

  3. 76 FR 550 - Second National Bed Bug Summit; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2009-0190; FRL-8858-4] Second National Bed Bug Summit... planning the second National Bed Bug Summit to be held February 1 and 2, 2011, on the topic of the bed bug resurgence in the United States. The goal of this meeting is to review the current bed bug problem and...

  4. Topical photosan-mediated photodynamic therapy for DMBA-induced hamster buccal pouch early cancer lesions: an in vivo study

    NASA Astrophysics Data System (ADS)

    Hsu, Yih-Chih; Chang, Walter Hong-Shong; Chang, Junn-Liang; Liu, Kuang-Ting; Chiang, Chun-Pin; Liu, Chung-Ji; Chen, Chih-Ping

    2011-03-01

    Oral cancer has becomes the most prominent cancer disease in recent years in Taiwan. The reason is the betel nut chewing habit combing with smoking and alcohol-drinking lifestyle of people results in oral cancer becomes the fastest growth incident cancer amongst other major cancer diseases. In previous studies showed that photosan, haematoporphyrin derivative (HPD), has demonstrated effective PDT results on human head and neck disease studies. To avoid the systemic phototoxic effect of photosan, this study was designed to use a topical photosan-mediated PDT for treatment of DMBA-induced hamster buccal pouch cancerous lesions. DMBA was applied to one of the buccal pouches of hamsters thrice a week for 10 to 12 weeks. Cancerous lesions were induced and proven by histological examination. These DMBA-induced cancerous lesions were used for testing the efficacy of topical photosan-mediated PDT. Before PDT, fluorescence spectroscopy was used to determine when photosan reached its peak level in the lesional epithelial cells after topical application of photosan gel. We found that photosan reached its peak level in cancerous lesions about 13.5 min after topical application of photosan gel. The cancerous lesions in hamsters were then treated with topical photosan-mediated PDT (fluence rate: 600 mW/cm2; light exposure dose 200 J/cm2) using the portable Lumacare 635 nm fiber-guided light device. Visual examination demonstrated that topical photosan-mediated PDT was an applicable treatment modality for DMBA-induced hamster buccal pouch cancerous lesions.

  5. Multiple Perspectives on the Topic of Scientists and Education and Public Outreach

    NASA Astrophysics Data System (ADS)

    Peticolas, L. M.

    2011-12-01

    This presentation aims to share the author's understanding of the complex topic of scientist involvement in and attitudes about Education and Public Outreach (E/PO) by approaching the topic from four viewpoints. The first perspective is from the author's own journey starting as a post-doctoral fellow engaged in limited ways in education and public outreach to full-time E/PO professional. The second perspective comes from discussions with scientists on the topic of E/PO. Evaluation data of scientists' involvement in a community college space science seminar series provides a third perspective. And the final perspective approaches the topic from the vantage point of research on scientist involvement in E/PO. From these multiple perspectives, there is evidence that that there exists ample passion for education and outreach in the scientific community. However, the path from passion to meaningful engagement of audiences and understandings of educational pedagogies continues to be difficult for a variety of reasons, such as: 1) a tendency to teach as one was taught rather than changing teaching practices based on research on how people learn, 2) a lack of time to collaborate and partner with appropriate educational professionals or institutions, 3) a lack of awareness (or a lack of time to develop an awareness) of an audience need or audience baseline understandings, and 4) a belief that science is supra-cultural and can be shared outside of a cultural context. It is suggested that the most effective way for scientists to engage in E/PO is to develop professional relationships with educators in the field of education and outreach for which the scientist is passionate (such as a middle school teacher if the passion lies in sharing science with middle school students.) E/PO professionals can also support and guide the passion with an understanding of best practices in E/PO. Spending time within the culture of the audience one wishes to work with can also be helpful in

  6. CELSS Program Meeting

    NASA Technical Reports Server (NTRS)

    Tremor, John W.; Macelroy, Robert D.

    1987-01-01

    A meeting on the potential contributions of plant science to the goals of Controlled Ecological Life Support System (CELSS) research produced discussions that helped to focus on a variety of topics. In the area of volatiles and soluble organics, microbial activity, disease, and productivity, participants emphasized the need to know more about the consequences of closure for the growth of plants. Under nutrient delivery systems, the problems focus on the need to maintain a stable, optimum nutrient system. Lighting systems discussions emphasized unique methods of direct lighting and development of improved irradiation sources. Flight experiment opportunities were outlined by one speaker. Documentation of the Plant Growth Module was discussed. The last day's discussion focused on the organization of the research group to be involved in the development and use of a two to three cubic meter sealed chamber and ancillary equipment.

  7. PREFACE: 16th Nordic Semiconductor Meeting

    NASA Astrophysics Data System (ADS)

    Pétur Gíslason, Hafliði; Guðmundsson, Viðar

    1994-01-01

    Some 30 years ago an informal meeting of the few Nordic specialists in semiconductor physics marked the beginning of what has become a biannual meeting of some hundred physicists and physics students from all the Nordic countries. The 16th Nordic Semiconductor Meeting took place at Laugarvatn, Iceland, June 12-15,1994. As a regional meeting the Nordic Semiconductor meeting has three characteristic features all of which distinguish it from more traditional international meetings in the field. First, it has the purpose of promoting Nordic cooperation in the international field of semiconductor physics. Research in the fields of advanced science and technology in the Nordic countries is likely to benefit from joining national forces before participating in the increasing European integration. Second, there is an unusually large fraction of graduate students amongst the participants of the Nordic Semiconductor Meeting. In fact, attending this conference is traditionally a part of the graduate program in seniconductor physics and technology. The Nordic Semiconductor Meeting is often the first conference of international character that graduate students attend in order to present a paper of poster. Third, there is an interdisciplinary quality of the meeting which is normally not the case for meetings of this size. In particular, the number of professional scientists from industry is comparable to the number of their academic colleagues. This is important for both groups, but perhaps the graduate students benefit most from presenting their results to both groups. The 16th Nordic Semiconductor Meeting, the first one in this series held in Iceland, attracted 129 active participants. The scientific programme was divided in twelve oral sessions. A novelty of this meeting was the emphasis on more fundamental physics in one of the two parallel sessions but more applied topics in the other, although the distinction was sometimes a matter of predilection. A poster session

  8. Critical Literacy and Transgender Topics in an Upper Elementary Classroom: A Portrait of Possibility

    ERIC Educational Resources Information Center

    Hermann-Wilmarth, Jill M.; Lannen, Rosemary; Ryan, Caitlin L.

    2017-01-01

    In this paper, we explore the intersection of critical literacy pedagogy, queer pedagogy, and transgender topics by turning our attention to the learning that supported the writing of an acrostic poem about Title IX and transgender students. We examine how this writing, in turn, created additional content and context that spurred others' learning.…

  9. Proceedings of the Human Factors Society 35th annual meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1991-01-01

    These volumes cover the proceedings of the 35th annual meeting of the Human Factors Society. Topics include: designing for the future of nuclear power plants international perspectives on advanced control room design; human performance assessment in the nuclear power industry; validity of strength tests for predicting endurance of coal miners, psychosocial issues in hazard management and nuclear power plants; and human factors at the DOE's national laboratories.

  10. Topical NSAIDs for chronic musculoskeletal pain in adults

    PubMed Central

    Derry, Sheena; Moore, R Andrew; Rabbie, Roy

    2014-01-01

    compared a topical NSAID with placebo. Topical NSAIDs were significantly more effective than placebo for reducing pain due to chronic musculoskeletal conditions. The best data were for topical diclofenac in osteoarthritis, where the NNT for at least 50% pain relief over 8 to 12 weeks compared with placebo was 6.4 for the solution, and 11 for the gel formulation. There were too few data of good quality to calculate NNTs for other individual topical NSAIDs compared with placebo. Direct comparison of topical NSAID with an oral NSAID did not show any difference in efficacy. There was an increase in local adverse events (mostly mild skin reactions) with topical NSAIDs compared with placebo or oral NSAIDs, but no increase in serious adverse events. Gastrointestinal adverse events with topical NSAID did not differ from placebo, but were less frequent than with oral NSAIDs. A substantial amount of data from unpublished studies was unavailable. Much of this probably relates to formulations that have never been marketed. Authors’ conclusions Topical NSAIDs can provide good levels of pain relief; topical diclofenac solution is equivalent to that of oral NSAIDs in knee and hand osteoarthritis, but there is no evidence for other chronic painful conditions. Formulation can influence efficacy. The incidence of local adverse events is increased with topical NSAIDs, but gastrointestinal adverse events are reduced compared with oral NSAIDs. PMID:22972108

  11. Identifying, Instructing and Rehabilitating South East Asian Students with Special Needs and Counseling Their Parents. Report of a Meeting Held at the Annual Conference of the National Association for South East Asian Students with Special Needs (San Francisco, California, March 13, 1985) and a Workshop (June 9-12, 1985).

    ERIC Educational Resources Information Center

    Dao, Mai; Grossman, Herbert

    The report provides background information on the educational needs of disabled South East Asian students and presents four papers from a meeting and workshop on the topic held respectively in March and June of 1985. A draft of an action plan advocated by meeting participants addresses ways to meet five major needs: (1) to obtain information on…

  12. Topical Therapies in Psoriasis

    PubMed Central

    Torsekar, R.; Gautam, Manjyot M.

    2017-01-01

    Topical therapy as monotherapy is useful in psoriasis patients with mild disease. Topical agents are also used as adjuvant for moderate-to-severe disease who are being concurrently treated with either ultraviolet light or systemic medications. Emollients are useful adjuncts to the treatment of psoriasis. Use of older topical agents such as anthralin and coal tar has declined over the years. However, they are cheaper and can still be used for the treatment of difficult psoriasis refractory to conventional treatment. Salicylic acid can be used in combination with other topical therapies such as topical corticosteroids (TCS) and calcineurin inhibitors for the treatment of thick limited plaques to increase the absorption of the latter into the psoriatic plaques. Low- to mid-potent TCS are used in facial/flexural psoriasis and high potent over palmoplantar/thick psoriasis lesions. The addition of noncorticosteroid treatment can also facilitate the avoidance of long-term daily TCS. Tacrolimus and pimecrolimus can be used for the treatment of facial and intertriginous psoriasis. Tazarotene is indicated for stable plaque psoriasis usually in combination with other therapies such as TCS. Vitamin D analogs alone in combination with TCS are useful in stable plaques over limbs and palmoplantar psoriasis. Topical therapies for scalp psoriasis include TCS, Vitamin D analogs, salicylic acid, coal tar, and anthralin in various formulations such as solutions, foams, and shampoos. TCS, vitamin D analogs, and tazarotene can be used in the treatment of nail psoriasis. PMID:28761838

  13. Automatic sleep classification using a data-driven topic model reveals latent sleep states.

    PubMed

    Koch, Henriette; Christensen, Julie A E; Frandsen, Rune; Zoetmulder, Marielle; Arvastson, Lars; Christensen, Soren R; Jennum, Poul; Sorensen, Helge B D

    2014-09-30

    The golden standard for sleep classification uses manual scoring of polysomnography despite points of criticism such as oversimplification, low inter-rater reliability and the standard being designed on young and healthy subjects. To meet the criticism and reveal the latent sleep states, this study developed a general and automatic sleep classifier using a data-driven approach. Spectral EEG and EOG measures and eye correlation in 1s windows were calculated and each sleep epoch was expressed as a mixture of probabilities of latent sleep states by using the topic model Latent Dirichlet Allocation. Model application was tested on control subjects and patients with periodic leg movements (PLM) representing a non-neurodegenerative group, and patients with idiopathic REM sleep behavior disorder (iRBD) and Parkinson's Disease (PD) representing a neurodegenerative group. The model was optimized using 50 subjects and validated on 76 subjects. The optimized sleep model used six topics, and the topic probabilities changed smoothly during transitions. According to the manual scorings, the model scored an overall subject-specific accuracy of 68.3 ± 7.44 (% μ ± σ) and group specific accuracies of 69.0 ± 4.62 (control), 70.1 ± 5.10 (PLM), 67.2 ± 8.30 (iRBD) and 67.7 ± 9.07 (PD). Statistics of the latent sleep state content showed accordances to the sleep stages defined in the golden standard. However, this study indicates that sleep contains six diverse latent sleep states and that state transitions are continuous processes. The model is generally applicable and may contribute to the research in neurodegenerative diseases and sleep disorders. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. 76 FR 8353 - Positioning Systems Directorate Will Be Hosting an Interface Control Working Group (ICWG) Meeting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-14

    ... an Interface Control Working Group (ICWG) Meeting for Document ICD-GPS-870 AGENCY: Interface Control Working Group (ICWG) meeting for document ICD-GPS-870. ACTION: Meeting Notice. SUMMARY: This notice... Working Group (ICWG) meeting for document ICD-GPS-870, Navstar Next Generation GPS Operational Control...

  15. A novel two-step kit for topical treatment of tinea pedis--an open study.

    PubMed

    Shemer, A; Grunwald, M H; Davidovici, B; Nathansohn, N; Amichai, B

    2010-09-01

    Tinea pedis is a common skin disease affecting most of the population during their lifetime. Topical and systemic treatments give only temporary relief. To evaluate the efficacy and safety of a new topical treatment for moderate-to-severe tinea pedis. Fifty patients suffering from tinea pedis were treated in two stages: the active stage--single use of the novel topical solution for 45 min and novel cream twice weekly for 4 weeks; the preventive stage--cream application once weekly for 10 months. Forty-five patients completed the active stage and achieved 76% cure rate. The medication was well tolerated; one patient dropped from the study because of very mild irritation. No other topical or systemic side effects were noted. Another five patients were lost to follow-up during the preventive stage. The total cure rate after the preventive stage was 70%. This novel treatment was found to be effective, well tolerated and safe in the treatment of moderate and severe tinea pedis during the active and the preventive stages.

  16. UHMS position statement: topical oxygen for chronic wounds.

    PubMed

    Feldmeier, J J; Hopf, H W; Warriner, R A; Fife, C E; Gesell, L B; Bennett, M

    2005-01-01

    A small body of literature has been published reporting the application of topical oxygen for chronic non-healing wounds . Frequently, and erroneously, this form of oxygen administration has been referred to as "topical hyperbaric oxygen therapy" or even more erroneously "hyperbaric oxygen therapy." The advocates of topical oxygen claim several advantages over systemic hyperbaric oxygen including decreased cost, increased safety, decreased complications and putative physiologic effects including decreased free radical formation and more efficient delivery of oxygen to the wound surface. With topical oxygen an airtight chamber or polyethylene bag is sealed around a limb or the trunk by either a constriction/tourniquet device or by tape and high flow (usually 10 liters per minute) oxygen is introduced into the bag and over the wound. Pressures just over 1.0 atmospheres absolute (atm abs) (typically 1.004 to 1.013 atm abs) are recommended because higher pressures could decrease arterial/capillary inflow. The premise for topical oxygen, the diffusion of oxygen into the wound adequate to enhance healing, is attractive (though not proven) and its delivery is certainly less complex and expensive than hyperbaric oxygen. When discussing the physiology of topical oxygen, its proponents frequently reference studies of systemic hyperbaric oxygen suggesting that mechanisms are equally applicable to both topical and systemic high pressure oxygen delivery. In fact, however, the two are very different. To date, mechanisms of action whereby topical oxygen might be effective have not been defined or substantiated. Conversely, cellular toxicities due to extended courses of topical oxygen have been reported, although, again these data are not conclusive, and no mechanism for toxicity has been examined scientifically. Generally, collagen production and fibroblast proliferation are considered evidence of improved healing, and these are both enhanced by hyperbaric oxygen therapy

  17. Digest of Papers: Forty-Eighth Annual Meeting of American Orthopsychiatric Association (Washington, D.C., March 21-24, 1971)

    ERIC Educational Resources Information Center

    Eisenberg, Leon, Ed.

    1971-01-01

    The entire journal contains summaries of topics and papers delivered at the Annual Meeting of American Orthopsychiatry (48th, March 21-24, 1971, Washington, D.C.). Author, title, and session indexes are provided. (RD)

  18. Topicality and impact in social media: diverse messages, focused messengers.

    PubMed

    Weng, Lilian; Menczer, Filippo

    2015-01-01

    We have a limited understanding of the factors that make people influential and topics popular in social media. Are users who comment on a variety of matters more likely to achieve high influence than those who stay focused? Do general subjects tend to be more popular than specific ones? Questions like these demand a way to detect the topics hidden behind messages associated with an individual or a keyword, and a gauge of similarity among these topics. Here we develop such an approach to identify clusters of similar hashtags in Twitter by detecting communities in the hashtag co-occurrence network. Then the topical diversity of a user's interests is quantified by the entropy of her hashtags across different topic clusters. A similar measure is applied to hashtags, based on co-occurring tags. We find that high topical diversity of early adopters or co-occurring tags implies high future popularity of hashtags. In contrast, low diversity helps an individual accumulate social influence. In short, diverse messages and focused messengers are more likely to gain impact.

  19. Topicality and Impact in Social Media: Diverse Messages, Focused Messengers

    PubMed Central

    Weng, Lilian; Menczer, Filippo

    2015-01-01

    We have a limited understanding of the factors that make people influential and topics popular in social media. Are users who comment on a variety of matters more likely to achieve high influence than those who stay focused? Do general subjects tend to be more popular than specific ones? Questions like these demand a way to detect the topics hidden behind messages associated with an individual or a keyword, and a gauge of similarity among these topics. Here we develop such an approach to identify clusters of similar hashtags in Twitter by detecting communities in the hashtag co-occurrence network. Then the topical diversity of a user’s interests is quantified by the entropy of her hashtags across different topic clusters. A similar measure is applied to hashtags, based on co-occurring tags. We find that high topical diversity of early adopters or co-occurring tags implies high future popularity of hashtags. In contrast, low diversity helps an individual accumulate social influence. In short, diverse messages and focused messengers are more likely to gain impact. PMID:25710685

  20. The Publication Rate of Abstracts Presented at the 2003 Urological Brazilian Meeting

    PubMed Central

    Oliveira, Leonardo Resende Sousa; Figueiredo, André Avarese; Choi, Mauro; Ferrarez, Carlos Eduardo Prata Fernandes; Bastos, Andre Netto; Netto, Jose Murillo Bastos

    2009-01-01

    OBJECTIVE: To determine the publication rate of orally-presented abstracts from the 2003 Urological Brazilian Meeting, as well as the factors determining this publication rate. MATERIALS AND METHODS: The publication rate of the 313 orally-presented abstracts at the 2003 Urological Brazilian Meeting was evaluated by scanning the Lilacs, Scielo and Medline databases. The time between presentation and publication, the state and country of the abstract, the research methodology (cross-sectional, case-control, retrospective case series, prospective case series or clinical trial), whether drugs were utilized and the topic of the study were all characterized. RESULTS: Thirty-nine percent of the abstracts were published after a median time of 14 months (range: 1 to 51 months). There were high publication rates for cross-sectional abstracts (75%), drug utilization studies (51.3%), clinical trials (50%) and prospective case series’ (48.1%). However, there was only a moderate statistical trend towards a higher publication rate in the prospective case series (p=0.07), while the retrospective case series’ showed statistically lower publication rates than the other groups (33.7%, p=0.04). Abstracts on laparoscopic surgery had the highest publication rate (61.9%, p=0.03) compared to others topics. In 57% of the unpublished abstracts, there was no interest in or attempt to publish, and rejection was responsible for the lack of publication of only 4% of the abstracts. CONCLUSION: The publication rate of the orally-presented abstracts from the 2003 Urological Brazilian Meeting was comparable to that of international congresses. The subsequent publication of presented abstracts and the selection of prospective studies with stronger evidence should be encouraged and may improve the scientific quality of the meeting. PMID:19488593

  1. Atopic dermatitis: a review of topical nonsteroid therapy

    PubMed Central

    Papier, Ariana

    2018-01-01

    Background Atopic dermatitis is a chronic inflammatory skin condition that affects up to 20% of children and 3% of adults globally. Although topical corticosteroids are considered to be the first-line agents, they can be associated with cutaneous and systemic adverse effects. Since the early 2000s, two new classes of nonsteroid topical therapies, topical calcineurin inhibitors and phosphodiesterase 4 (PDE4) inhibitors, have been introduced and provide a safe treatment alternative. Method We performed a search and review of clinical trials that examined the safety and efficacy of topical calcineurin inhibitors and PDE4 inhibitors. The search was conducted using the PubMed database as well as preselected keywords and filters. This review focuses on the safety and efficacy of each therapy. Results Sixty-nine clinical trials identified in this study have demonstrated the efficacy and safety of topical calcineurin and a single novel PDE4 inhibitor in the treatment of atopic dermatitis. Topical calcineurin inhibitors have been shown to be effective in both achieving lesion clearance as well as reducing relapse when used long-term and proactively. Similarly, in clinical trials the PDE4 inhibitor showed success in lesion clearance and symptom management. All three therapies (pimecrolimus, tacrolimus, crisaborole) are associated with low systemic absorption. No clinical trials to date have shown an increased risk of systemic adverse events or malignancy such as lymphoma. The most commonly reported treatment-related adverse event across all three therapies was application-site discomfort, pain or pruritus. It is important to note that long-term studies are not yet available for the novel PDE4 inhibitor. Discussion Topical calcineurin inhibitors provide a safe and effective alternative to topical corticosteroid use in the treatment of atopic dermatitis. Although the US Food and Drug Administration (FDA) black box warning for topical calcineurin inhibitors remains, studies

  2. Global health ethics: an introduction to prominent theories and relevant topics

    PubMed Central

    Stapleton, Greg; Schröder-Bäck, Peter; Laaser, Ulrich; Meershoek, Agnes; Popa, Daniela

    2014-01-01

    Global health ethics is a relatively new term that is used to conceptualize the process of applying moral value to health issues that are typically characterized by a global level effect or require action coordinated at a global level. It is important to acknowledge that this account of global health ethics takes a predominantly geographic approach and may infer that the subject relates primarily to macro-level health phenomena. However, global health ethics could alternatively be thought of as another branch of health ethics. It may then relate to specific topics in themselves, which might also include micro-level health phenomena. In its broadest sense, global health ethics is a normative project that is best characterized by the challenge of developing common values and universal norms for responding to global health threats. Consequently, many subjects fall within its scope. Whilst several accounts of global health ethics have been conceptualized in the literature, a concise demarcation of the paradigm is still needed. Through means of a literature review, this paper presents a two-part introduction to global health ethics. First, the framework of ‘borrowed’ ethics that currently form the core of global health ethics is discussed in relation to two essential ethical considerations: 1) what is the moral significance of health and 2) what is the moral significance of boundaries? Second, a selection of exemplar ethical topics is presented to illustrate the range of topics within global health ethics. PMID:24560262

  3. Global health ethics: an introduction to prominent theories and relevant topics.

    PubMed

    Stapleton, Greg; Schröder-Bäck, Peter; Laaser, Ulrich; Meershoek, Agnes; Popa, Daniela

    2014-01-01

    Global health ethics is a relatively new term that is used to conceptualize the process of applying moral value to health issues that are typically characterized by a global level effect or require action coordinated at a global level. It is important to acknowledge that this account of global health ethics takes a predominantly geographic approach and may infer that the subject relates primarily to macro-level health phenomena. However, global health ethics could alternatively be thought of as another branch of health ethics. It may then relate to specific topics in themselves, which might also include micro-level health phenomena. In its broadest sense, global health ethics is a normative project that is best characterized by the challenge of developing common values and universal norms for responding to global health threats. Consequently, many subjects fall within its scope. Whilst several accounts of global health ethics have been conceptualized in the literature, a concise demarcation of the paradigm is still needed. Through means of a literature review, this paper presents a two-part introduction to global health ethics. First, the framework of 'borrowed' ethics that currently form the core of global health ethics is discussed in relation to two essential ethical considerations: 1) what is the moral significance of health and 2) what is the moral significance of boundaries? Second, a selection of exemplar ethical topics is presented to illustrate the range of topics within global health ethics.

  4. Probability workshop to be better in probability topic

    NASA Astrophysics Data System (ADS)

    Asmat, Aszila; Ujang, Suriyati; Wahid, Sharifah Norhuda Syed

    2015-02-01

    The purpose of the present study was to examine whether statistics anxiety and attitudes towards probability topic among students in higher education level have an effect on their performance. 62 fourth semester science students were given statistics anxiety questionnaires about their perception towards probability topic. Result indicated that students' performance in probability topic is not related to anxiety level, which means that the higher level in statistics anxiety will not cause lower score in probability topic performance. The study also revealed that motivated students gained from probability workshop ensure that their performance in probability topic shows a positive improvement compared before the workshop. In addition there exists a significance difference in students' performance between genders with better achievement among female students compared to male students. Thus, more initiatives in learning programs with different teaching approaches is needed to provide useful information in improving student learning outcome in higher learning institution.

  5. Computationally driven drug discovery meeting-3 - Verona (Italy): 4 - 6th of March 2014.

    PubMed

    Costantino, Gabriele

    2014-12-01

    The following article reports on the results and the outcome of a meeting organised at the Aptuit Auditorium in Verona (Italy), which highlighted the current applications of state-of-the-art computational science to drug design in Italy. The meeting, which had > 100 people in attendance, consisted of over 40 presentations and included keynote lectures given by world-renowned speakers. The topics included in the meeting are areas related to ligand and structure-based ligand design and library design and screening; it also provided discussion pertaining to chemometrics. The meeting also stressed the importance of public-private collaboration and reviewed the different approaches to computationally driven drug discovery taken within academia and industry. The meeting helped define the current position of state-of-the-art computational drug discovery in Italy, pointing out criticalities and assets. This kind of focused meeting is important in the sense that it lends the opportunity of a restricted yet representative community of fellow professionals to deeply discuss the current methodological approaches and provide future perspectives for computationally driven drug discovery.

  6. Correlated Topic Vector for Scene Classification.

    PubMed

    Wei, Pengxu; Qin, Fei; Wan, Fang; Zhu, Yi; Jiao, Jianbin; Ye, Qixiang

    2017-07-01

    Scene images usually involve semantic correlations, particularly when considering large-scale image data sets. This paper proposes a novel generative image representation, correlated topic vector, to model such semantic correlations. Oriented from the correlated topic model, correlated topic vector intends to naturally utilize the correlations among topics, which are seldom considered in the conventional feature encoding, e.g., Fisher vector, but do exist in scene images. It is expected that the involvement of correlations can increase the discriminative capability of the learned generative model and consequently improve the recognition accuracy. Incorporated with the Fisher kernel method, correlated topic vector inherits the advantages of Fisher vector. The contributions to the topics of visual words have been further employed by incorporating the Fisher kernel framework to indicate the differences among scenes. Combined with the deep convolutional neural network (CNN) features and Gibbs sampling solution, correlated topic vector shows great potential when processing large-scale and complex scene image data sets. Experiments on two scene image data sets demonstrate that correlated topic vector improves significantly the deep CNN features, and outperforms existing Fisher kernel-based features.

  7. 2007 international meeting on Reduced Enrichment for Research and Test Reactors (RERTR). Abstracts and available papers presented at the meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    2008-07-15

    The Meeting papers discuss research and test reactor fuel performance, manufacturing and testing. Some of the main topics are: conversion from HEU to LEU in different reactors and corresponding problems and activities; flux performance and core lifetime analysis with HEU and LEU fuels; physics and safety characteristics; measurement of gamma field parameters in core with LEU fuel; nondestructive analysis of RERTR fuel; thermal hydraulic analysis; fuel interactions; transient analyses and thermal hydraulics for HEU and LEU cores; microstructure research reactor fuels; post irradiation analysis and performance; computer codes and other related problems.

  8. Fixed cutaneous sporotrichosis treated with topical amphotericin B in an immune suppressed patient.

    PubMed

    Mahajan, Vikram K; Mehta, Karaninder S; Chauhan, Pushpinder S; Gupta, Mrinal; Sharma, Rajni; Rawat, Ritu

    2015-03-01

    Both fixed cutaneous and lymphocutaneous sporotrichosis are associated with significant morbidity due to chronicity. Although treatment with itraconazole, saturated solution of potassium iodide or terbinafine is recommended in most cases, the described patient with fixed cutaneous sporotrichosis could not tolerate any of these. Her lesion healed after 8weeks of topical amphotericin-B (0.1% w/w). Topical amphotericin-B appears useful treatment modality for uncomplicated cutaneous sporotrichosis when systemic treatment needs deferment, remains contraindicated, or in pediatric patients.

  9. Long-term maintenance therapy for vulvar lichen sclerosus: the results of a randomized study comparing topical vitamin E with an emollient.

    PubMed

    Virgili, Annarosa; Minghetti, Sara; Borghi, Alessandro; Corazza, Monica

    2013-04-01

    The chronic and relapsing nature of vulvar lichen sclerosus (VLS) represents a challenge for its long-term management after an effective treatment with topical corticosteroids. To compare the effect of topical vitamin E with that of an emollient in reducing the risk of VLS relapse over a 52-week maintenance treatment. 156 patients with VLS were enrolled in a 12-week active treatment phase on topical 0.1% mometasone furoate ointment once daily. Those who achieved disease remission entered a 52-week maintenance phase in which patients were randomized to apply either an emollient or topical vitamin E once daily. 80 patients entered the maintenance phase. At 52 weeks, for the vitamin E maintenance group, the cumulative crude relapse rate was 27.8% and the cumulative modified crude relapse rate was 55.6%. For the emollient maintenance group, the cumulative crude relapse rate was 22.7% and the cumulative modified crude relapse rate was 50.0%. The median time to relapse was 20 weeks for the vitamin E group and 18.7 weeks for the emollient group. Once VLS has been stabilized with topical corticosteroids, long-term treatment with both vitamin E and emollients may be considered in maintain LS remission.

  10. 75 FR 25211 - Meeting of the Defense Department Advisory Committee on Women in the Services (DACOWITS)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... briefing from Sexual Assault and Prevention and Response Office. The meeting is open to the public, subject... announcements --Discussion on Committee's vision, philosophy, and topics to pursue --Briefings from Sexual Assault Prevention and Response Office --Public Forum Written Statements Individuals submitting a written...

  11. 77 FR 10786 - Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Reliability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-23

    ... Modeling Application Guide.'' The Subcommittee will hear presentations by and hold discussions with the NRC staff and other interested persons regarding this matter. The Subcommittee will gather information.../acrs . Information regarding topics to be discussed, changes to the agenda, whether the meeting has...

  12. Assessment of Course-Based Undergraduate Research Experiences: A Meeting Report

    PubMed Central

    Auchincloss, Lisa Corwin; Laursen, Sandra L.; Branchaw, Janet L.; Eagan, Kevin; Graham, Mark; Hanauer, David I.; Lawrie, Gwendolyn; McLinn, Colleen M.; Pelaez, Nancy; Rowland, Susan; Towns, Marcy; Trautmann, Nancy M.; Varma-Nelson, Pratibha; Weston, Timothy J.; Dolan, Erin L.

    2014-01-01

    The Course-Based Undergraduate Research Experiences Network (CUREnet) was initiated in 2012 with funding from the National Science Foundation program for Research Coordination Networks in Undergraduate Biology Education. CUREnet aims to address topics, problems, and opportunities inherent to integrating research experiences into undergraduate courses. During CUREnet meetings and discussions, it became apparent that there is need for a clear definition of what constitutes a CURE and systematic exploration of what makes CUREs meaningful in terms of student learning. Thus, we assembled a small working group of people with expertise in CURE instruction and assessment to: 1) draft an operational definition of a CURE, with the aim of defining what makes a laboratory course or project a “research experience”; 2) summarize research on CUREs, as well as findings from studies of undergraduate research internships that would be useful for thinking about how students are influenced by participating in CUREs; and 3) identify areas of greatest need with respect to CURE assessment, and directions for future research on and evaluation of CUREs. This report summarizes the outcomes and recommendations of this meeting. PMID:24591501

  13. Naftifine Hydrochloride Gel 2%: An Effective Topical Treatment for Moccasin-Type Tinea Pedis.

    PubMed

    Stein Gold, Linda F; Vlahovic, Tracey; Verma, Amit; Olayinka, Babajide; Fleischer, Alan B

    2015-10-01

    statistically higher (P < 0.0001) for mycological cure rate (65.8% vs. 7.8%), treatment effectiveness (51.4% vs 4.4%), and complete cure rate (19.2% vs 0.9%). Two weeks application of topical naftifine gel 2% is an effective monotherapy treatment for moccasin tinea pedis.

  14. PREFACE: 11th IAEA Technical Meeting on H-mode Physics and Transport Barriers

    NASA Astrophysics Data System (ADS)

    Takizuka, Tomonori

    2008-07-01

    This volume of Journal of Physics: Conference Series contains papers based on invited talks and contributed posters presented at the 11th IAEA Technical Meeting on H-mode Physics and Transport Barriers. This meeting was held at the Tsukuba International Congress Center in Tsukuba, Japan, on 26-28 September 2007, and was organized jointly by the Japan Atomic Energy Agency and the University of Tsukuba. The previous ten meetings in this series were held in San Diego (USA) 1987, Gut Ising (Germany) 1989, Abingdon (UK) 1991, Naka (Japan) 1993, Princeton (USA) 1995, Kloster Seeon (Germany) 1997, Oxford (UK) 1999, Toki (Japan) 2001, San Diego (USA) 2003, and St Petersburg (Russia) 2005. The purpose of the eleventh meeting was to present and discuss new results on H-mode (edge transport barrier, ETB) and internal transport barrier, ITB, experiments, theory and modeling in magnetic fusion research. It was expected that contributions give new and improved insights into the physics mechanisms behind high confinement modes of H-mode and ITBs. Ultimately, this research should lead to improved projections for ITER. As has been the tradition at the recent meetings of this series, the program was subdivided into six topics. The topics selected for the eleventh meeting were: H-mode transition and the pedestal-width Dynamics in ETB: ELM threshold, non-linear evolution and suppression, etc Transport relations of various quantities including turbulence in plasmas with ITB: rotation physics is especially highlighted Transport barriers in non-axisymmetric magnetic fields Theory and simulation on transport barriers Projections of transport barrier physics to ITER For each topic there was an invited talk presenting an overview of the topic, based on contributions to the meeting and on recently published external results. The six invited talks were: A Leonard (GA, USA): Progress in characterization of the H-mode pedestal and L-H transition N Oyama (JAEA, Japan): Progress and issues in

  15. Progressive Learning of Topic Modeling Parameters: A Visual Analytics Framework.

    PubMed

    El-Assady, Mennatallah; Sevastjanova, Rita; Sperrle, Fabian; Keim, Daniel; Collins, Christopher

    2018-01-01

    Topic modeling algorithms are widely used to analyze the thematic composition of text corpora but remain difficult to interpret and adjust. Addressing these limitations, we present a modular visual analytics framework, tackling the understandability and adaptability of topic models through a user-driven reinforcement learning process which does not require a deep understanding of the underlying topic modeling algorithms. Given a document corpus, our approach initializes two algorithm configurations based on a parameter space analysis that enhances document separability. We abstract the model complexity in an interactive visual workspace for exploring the automatic matching results of two models, investigating topic summaries, analyzing parameter distributions, and reviewing documents. The main contribution of our work is an iterative decision-making technique in which users provide a document-based relevance feedback that allows the framework to converge to a user-endorsed topic distribution. We also report feedback from a two-stage study which shows that our technique results in topic model quality improvements on two independent measures.

  16. Public affairs events at Fall Meeting

    NASA Astrophysics Data System (ADS)

    Uhlenbrock, Kristan

    2012-02-01

    AGU's Public Affairs team presented two workshop luncheons and hosted 17 oral and poster sessions at the 2011 Fall Meeting. Topics ranged from defining the importance of the geosciences, to climate change science for communities and institutions. The workshop luncheon "How to Be a Congressional Science Fellow or Mass Media Fellow" was a well-attended event with more than 115 participants. The luncheon provided the opportunity for audience members to ask fellow scientists about their experiences working either in Congress or as a reporter for a news organization. For scientists looking to expand their expertise outside the academic environment, these AGU fellowships are fantastic opportunities.

  17. Doha agreement meeting on terminology and definitions in groin pain in athletes

    PubMed Central

    Weir, Adam; Brukner, Peter; Delahunt, Eamonn; Ekstrand, Jan; Griffin, Damian; Khan, Karim M; Lovell, Greg; Meyers, William C; Muschaweck, Ulrike; Orchard, John; Paajanen, Hannu; Philippon, Marc; Reboul, Gilles; Robinson, Philip; Schache, Anthony G; Schilders, Ernest; Serner, Andreas; Silvers, Holly; Thorborg, Kristian; Tyler, Timothy; Verrall, Geoffrey; de Vos, Robert-Jan; Vuckovic, Zarko; Hölmich, Per

    2015-01-01

    Background Heterogeneous taxonomy of groin injuries in athletes adds confusion to this complicated area. Aim The ‘Doha agreement meeting on terminology and definitions in groin pain in athletes’ was convened to attempt to resolve this problem. Our aim was to agree on a standard terminology, along with accompanying definitions. Methods A one-day agreement meeting was held on 4 November 2014. Twenty-four international experts from 14 different countries participated. Systematic reviews were performed to give an up-to-date synthesis of the current evidence on major topics concerning groin pain in athletes. All members participated in a Delphi questionnaire prior to the meeting. Results Unanimous agreement was reached on the following terminology. The classification system has three major subheadings of groin pain in athletes: 1. Defined clinical entities for groin pain: Adductor-related, iliopsoas-related, inguinal-related and pubic-related groin pain. 2. Hip-related groin pain. 3. Other causes of groin pain in athletes. The definitions are included in this paper. Conclusions The Doha agreement meeting on terminology and definitions in groin pain in athletes reached a consensus on a clinically based taxonomy using three major categories. These definitions and terminology are based on history and physical examination to categorise athletes, making it simple and suitable for both clinical practice and research. PMID:26031643

  18. Spaceflight mechanics, 1993; AAS/AIAA Spaceflight Mechanics Meeting, 3rd, Pasadena, CA, Feb. 22-24, 1993, Parts 1 & 2

    NASA Technical Reports Server (NTRS)

    Melton, Robert G. (Editor); Wood, Lincoln J. (Editor); Thompson, Roger C. (Editor); Kerridge, Stuart J. (Editor)

    1993-01-01

    Papers from the third annual Spaceflight Mechanics Meeting are presented. The topics covered include the following: attitude dynamics and control; large flexible structures; intercept and rendezvous; rendezvous and orbit transfer; and trajectory optimization.

  19. Life sciences and space research X. Proceedings of the open meeting of working group 5 of the fourteenth plenary meeting of COSPAR, Seattle, Washington, June 21--July 2, 1971

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vishniac, W.

    1972-01-01

    From 14th COSPAR meeting on life sciences and space research X; Seattle, Washington, USA (17 Jun 1971). Separate asbstracts were prepared for 7 of the 27 papers appearing in these proceedings. The other papers discuss topics in the following general areas: planetary quarantine; effects of weightlessness, effects of space on living matter; and preparations for the exploration of Mars. (ERB)

  20. Topical botulinum toxin.

    PubMed

    Collins, Ashley; Nasir, Adnan

    2010-03-01

    Nanotechnology is a rapidly growing discipline that capitalizes on the unique properties of matter engineered on the nanoscale. Vehicles incorporating nanotechnology have led to great strides in drug delivery, allowing for increased active ingredient stability, bioavailability, and site-specific targeting. Botulinum toxin has historically been used for the correction of neurological and neuromuscular disorders, such as torticollis, blepharospasm, and strabismus. Recent dermatological indications have been for the management of axillary hyperhydrosis and facial rhytides. Traditional methods of botulinum toxin delivery have been needle-based. These have been associated with increased pain and cost. Newer methods of botulinum toxin formulation have yielded topical preparations that are bioactive in small pilot clinical studies. While there are some risks associated with topical delivery, the refinement and standardization of delivery systems and techniques for the topical administration of botulinum toxin using nanotechnology is anticipated in the near future.

  1. The past and future of chemical information - A report of the Chemical Information Division Session of the 200th Meeting of the American Chemical Society

    NASA Astrophysics Data System (ADS)

    Tokizane, Soichi

    At the historical meeting of the ACS CINF Division, the 1990 Herman Skolnik Award was presented to Dr. Ernst Meyer, who at BASF in Germany had developed a computer storage and retrieval system of chemical structures in 1960s. His and his colleagues' speeches in the award symposium were about the history of the development of chemical structure information in Germany. In the symposium of the Markush structure system, a hottest topic in this field, CAS's MARPAT and Markush-DARC co-developed by Questel, INPI, and Derwent were discussed by many papers. Other topics of this meeting were discussed, too.

  2. Topical methotrexate pretreatment enhances the therapeutic effect of topical 5-aminolevulinic acid-mediated photodynamic therapy on hamster buccal pouch precancers.

    PubMed

    Yang, Deng-Fu; Lee, Jeng-Woei; Chen, Hsin-Ming; Hsu, Yih-Chih

    2014-09-01

    Topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) is effective for treatment of human oral precancerous lesions. This animal study aimed to assess whether topical methotrexate (MTX) pretreatment could enhance the therapeutic effect of topical ALA-PDT on hamster buccal pouch precancerous lesions. Twenty hamster buccal pouch precancerous lesions were treated with either topical ALA-PDT with topical MTX pretreatment (topical MTX-ALA-PDT group, n = 10) or topical ALA-PDT alone (topical ALA-PDT group, n = 10). The intracellular protoporphyrin IX (PpIX) level in another 12 precancerous lesions (n = 6 for either the topical MTX-ALA or topical ALA group) was monitored by fluorescence spectroscopy. The intracellular PpIX reached its peak level in precancerous lesions 6.5 hours and 2.5 hours after topical ALA application for the topical MTX-ALA group (5.63-fold higher in the lesion than in the normal mucosa) and topical ALA group (2.42-fold higher in the lesion than in the normal mucosa), respectively. The complete response rate of precancerous lesions was 80% for the topical MTX-ALA-PDT group and 70% for the topical ALA-PDT group. In addition, the topical MTX-ALA-PDT group required a significantly lower mean treatment number (2.1 ± 0.6) to achieve complete response than the topical ALA-PDT group (4.4 ± 1.3, p < 0.001)). Moreover, the topical MTX-ALA-PDT group had a lower recurrence rate (12.5%) than the topical ALA-PDT group (28.6%). We conclude that topical MTX-pretreatment can increase intracellular PpIX production in hamster buccal pouch precancerous lesions and significantly improves the outcomes of the precancerous lesions treated with topical ALA-PDT. Copyright © 2014. Published by Elsevier B.V.

  3. Comparison of the stability of topical isotretinoin and topical tretinoin and their efficacy in acne.

    PubMed

    Elbaum, D J

    1988-09-01

    After 4 hours of exposure to incandescent light, 80% of 0.05% topical isotretinoin and 60% of 0.05% topical tretinoin preparations remained in their original form. In contrast, after 2 hours of exposure to fluorescent light only 25% of topical tretinoin and possibly 60% of topical isotretinoin remained in their original forms. Longer exposure to fluorescent light did not result in further breakdown, and the final breakdown of both preparations was similar. A 12-week, double-blind clinical trial comparing isotretinoin (0.05%) with tretinoin (0.05%) applied topically to patients with moderate acne was carried out. Both preparations caused significant reductions in papules and pustules. However, neither treatment was significantly superior to the other in the reduction of acne lesions. This may be because both preparations are rapidly broken down to similar products when exposed to fluorescent light.

  4. Active experiments in space; Proceedings of the Topical Meeting of the Interdisciplinary Scientific Commission D (Meeting D3) of the COSPAR 28th Plenary Meeting, The Hague, Netherlands, June 25-July 6, 1990

    NASA Astrophysics Data System (ADS)

    Torbert, R.

    1992-12-01

    The present volume on active experiments in space discusses dynamic trapping of electrons in the Porcupine ionospheric ion beam experiment, plasma wave observations during electron gun experiments on ISEE-1, spatial coherence and electromagnetic wave generation during electron beam experiments in space, and recent experimental measurements of space platform charging at LEO altitudes. Attention is given to high voltage spheres in an unmagnetized plasma, energetic ion emission for active spacecraft control, the collective gyration of a heavy ion cloud in a magnetized plasma, and remote sensing of artificial luminous clouds by lidars. Topics addressed include modulation of the background flux of energetic particles by artificial injection, wave measurements in active experiments on plasma beam injection, field formation around negatively biased solar arrays in the LEO-plasma, and the registration of ELF waves in rocket-satellite experiments with plasma injection.

  5. Topical cyclosporine for atopic keratoconjunctivitis.

    PubMed

    González-López, Julio J; López-Alcalde, Jesús; Morcillo Laiz, Rafael; Fernández Buenaga, Roberto; Rebolleda Fernández, Gema

    2012-09-12

    Ophthalmologica Europaea from 2005 to July 2011. We included randomised controlled trials only. Two review authors independently extracted data. Due to the small number of studies and the diversity of outcome measures, interventions and participants, we presented results narratively. We found three RCTs with a total of 58 participants that were eligible for inclusion. There was significant variability between the trials in interventions, methodology and outcome measures and therefore we did not perform meta-analysis.One study reported on the use of 2% CsA in maize oil and two on the use of a commercial emulsion of 0.05% CsA. Of these three studies, one showed a beneficial effect of topical CsA in controlling signs and symptoms of AKC, one in controlling signs of AKC and one did not show evidence of an improvement. Only two studies analysed the effect of topical CsA in reducing topical steroid use; one showed a significant reduction in topical steroid use with CsA, but the other did not show evidence of this improvement. No serious adverse events were reported in the trials. This systematic review highlights the relative scarcity of controlled clinical trials assessing the efficacy of topical CsA therapy in AKC and suggests that evidence on the efficacy and safety of topical CsA treatment in patients with CsA remains limited. However, the data suggest that topical CsA may provide clinical and symptomatic relief in AKC and may help to reduce topical steroid use in patients with steroid-dependent or steroid-resistant AKC. No serious adverse events were reported. Reported adverse events in patients treated with topical CsA include intense stinging and eyelid skin maceration. One patient in the placebo group developed a severe allergic response to maize antigens. However, the total number of patients in the trials was too small to assess the safety of this treatment.Additional well-designed and powered RCTs of topical CsA in AKC are needed. Ideal study designs should include adequate

  6. The 5th Meeting of the Ad Hoc Panel on Terminal Configured Vehicles

    NASA Technical Reports Server (NTRS)

    1977-01-01

    A report of the fifth meeting of the NASA Research and Technology Advisory Council, Ad Hoc panel on Terminal Configured Vehicles is presented. Some of the following topics were discussed; (1) microwave landing systems; (2) whole word computer system status; (3) flight path angle control: (4) VTOL approaches and landing technology; and (5) simulation study in wind shear.

  7. On the Topical Structure of Medical Charts

    PubMed Central

    Archbold, Armar A.; Evans, David A.

    1989-01-01

    In a study of 55 H&P sections of hospital charts, we tested the hypothesis that topic-sub-topic sequencing is sufficiently regular to provide ‘missing’ information in the construction of explicit propositions from elliptical text. ‘Propositions’ were taken to be frames with the slots topic, sub-topic, method, site, attribute, value, and qualifier. Topic was identifiable in 96% of all cases; attribute-value pairs were uniquely recoverable from topics in 69% of all cases; site was co-determined by topic, method, and attribute. Our results suggest that uncertainties in the automated processing of H&P statements can be overcome by appealing to knowledge about the topical structure of medical charts.

  8. [Non adherence and topical steroids].

    PubMed

    Aubert, H; Barbarot, S

    2012-01-01

    Compliance raises very specific questions in dermatology related to the frequent use of local treatments: creams or ointments, including topical corticosteroids. The adherence in dermatology is a complex issue. It is difficult to quantify objectively because of the patient subjectivity, the constant adaptation to changes in the course of the disease, and due to the lack of adapted device. Moreover poor compliance may be related to topical corticosteroid phobia, defined as a fear vis-à-vis the topical corticosteroids, rational or not. The topical corticosteroid phobia is very common in the management of chronic inflammatory skin diseases especially in atopic dermatitis. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  9. Topic Negotiation in Peer Group Oral Assessment Situations: A Conversation Analytic Approach

    ERIC Educational Resources Information Center

    Gan, Zhengdong; Davison, Chris; Hamp-Lyons, Liz

    2009-01-01

    This study examines the production of topical talk in peer collaborative negotiation in an interactive assessment innovation context. The ability to stay on topic, to move from topic to topic and to introduce new topics appropriately is at the core of communicative competence. Applying conversation analysis (CA), we describe and analyze how one…

  10. Association Genetics of Populus trichocarpa or Resequencing in Populus: Towards Genome Wide Association Genetics (2011 JGI User Meeting)

    ScienceCinema

    Tuskan, Gerry

    2018-02-13

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Gerry Tuskan of Oak Ridge National Laboratory on Resequencing in Populus: Towards Genome Wide Association Genetics at the 6th annual Genomics of Energy Environment Meeting on March 23, 2011.

  11. Analysis and application of opinion model with multiple topic interactions.

    PubMed

    Xiong, Fei; Liu, Yun; Wang, Liang; Wang, Ximeng

    2017-08-01

    To reveal heterogeneous behaviors of opinion evolution in different scenarios, we propose an opinion model with topic interactions. Individual opinions and topic features are represented by a multidimensional vector. We measure an agent's action towards a specific topic by the product of opinion and topic feature. When pairs of agents interact for a topic, their actions are introduced to opinion updates with bounded confidence. Simulation results show that a transition from a disordered state to a consensus state occurs at a critical point of the tolerance threshold, which depends on the opinion dimension. The critical point increases as the dimension of opinions increases. Multiple topics promote opinion interactions and lead to the formation of macroscopic opinion clusters. In addition, more topics accelerate the evolutionary process and weaken the effect of network topology. We use two sets of large-scale real data to evaluate the model, and the results prove its effectiveness in characterizing a real evolutionary process. Our model achieves high performance in individual action prediction and even outperforms state-of-the-art methods. Meanwhile, our model has much smaller computational complexity. This paper provides a demonstration for possible practical applications of theoretical opinion dynamics.

  12. Program and Abstracts for Clay Minerals Society 28th Annual Meeting

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This volume contains abstracts that were accepted for presentation at the annual meeting. Some of the main topics covered include: (1) fundamental properties of minerals and methods of mineral analysis; (2) surface chemistry; (3) extraterrestrial clay minerals; (4) geothermometers and geochronometers; (5) smectite, vermiculite, illite, and related reactions; (6) soils and clays in environmental research; (7) kaolinite, halloysite, iron oxides, and mineral transformations; and (8) clays in lakes, basins, and reservoirs.

  13. Guidelines for the Selection of Topical Content in ESL Programs

    ERIC Educational Resources Information Center

    Deckert, Glenn

    2004-01-01

    The author contends that the topical content of ESL lesson materials in schools and universities is of ethical significance. Based on an established model for ethical judgment in social services, five guidelines for ethical selection of lesson topics are proposed and illustrated. Lesson topics must help ESL students: (a) adjust to local…

  14. Discriminative Relational Topic Models.

    PubMed

    Chen, Ning; Zhu, Jun; Xia, Fei; Zhang, Bo

    2015-05-01

    Relational topic models (RTMs) provide a probabilistic generative process to describe both the link structure and document contents for document networks, and they have shown promise on predicting network structures and discovering latent topic representations. However, existing RTMs have limitations in both the restricted model expressiveness and incapability of dealing with imbalanced network data. To expand the scope and improve the inference accuracy of RTMs, this paper presents three extensions: 1) unlike the common link likelihood with a diagonal weight matrix that allows the-same-topic interactions only, we generalize it to use a full weight matrix that captures all pairwise topic interactions and is applicable to asymmetric networks; 2) instead of doing standard Bayesian inference, we perform regularized Bayesian inference (RegBayes) with a regularization parameter to deal with the imbalanced link structure issue in real networks and improve the discriminative ability of learned latent representations; and 3) instead of doing variational approximation with strict mean-field assumptions, we present collapsed Gibbs sampling algorithms for the generalized relational topic models by exploring data augmentation without making restricting assumptions. Under the generic RegBayes framework, we carefully investigate two popular discriminative loss functions, namely, the logistic log-loss and the max-margin hinge loss. Experimental results on several real network datasets demonstrate the significance of these extensions on improving prediction performance.

  15. Clinical Comparison: Fast-Acting and Traditional Topical Dental Anesthetic

    PubMed Central

    DiMarco, Arthur C.; Wetmore, Ann O'Kelley

    2016-01-01

    A randomized, nonblinded clinical trial compared the effectiveness of an application method of a fast-acting refrigerant topical agent to a 20% benzocaine gel topical. In a split-mouth design, right and left anterior middle superior alveolar injections (N = 30) were administered with a 27-gauge needle at least 24 hours apart with preinjection topicals. Using a cotton-tipped applicator, a refrigerant topical was applied for 5 seconds and 20% benzocaine gel for 2 minutes on opposite sides at 2 separate appointments. Subjects self-reported pain perception after each injection using a visual analog scale (VAS). The mean VAS ratings demonstrated no significant difference between the 5-second application of the refrigerant (M = 16.2, SD = 17.7) and the 2-minute application of 20% benzocaine topical gel anesthetic (M = 17.9, SD = 18.2). Fifty-seven percent of the subjects reported greater pain reduction with the refrigerant, 33% reported greater pain reduction with 20% benzocaine, and 10% reported no difference. Results suggest the described method of application of a refrigerant as an oral topical anesthetic has a faster onset and provides similar benefit in pain reduction compared with 20% benzocaine gel. The refrigerant was easy to accomplish and well received by subjects, indicating potential for routine use in dentistry. PMID:27269661

  16. Clinical Comparison: Fast-Acting and Traditional Topical Dental Anesthetic.

    PubMed

    DiMarco, Arthur C; Wetmore, Ann O'Kelley

    2016-01-01

    A randomized, nonblinded clinical trial compared the effectiveness of an application method of a fast-acting refrigerant topical agent to a 20% benzocaine gel topical. In a split-mouth design, right and left anterior middle superior alveolar injections (N = 30) were administered with a 27-gauge needle at least 24 hours apart with preinjection topicals. Using a cotton-tipped applicator, a refrigerant topical was applied for 5 seconds and 20% benzocaine gel for 2 minutes on opposite sides at 2 separate appointments. Subjects self-reported pain perception after each injection using a visual analog scale (VAS). The mean VAS ratings demonstrated no significant difference between the 5-second application of the refrigerant (M = 16.2, SD = 17.7) and the 2-minute application of 20% benzocaine topical gel anesthetic (M = 17.9, SD = 18.2). Fifty-seven percent of the subjects reported greater pain reduction with the refrigerant, 33% reported greater pain reduction with 20% benzocaine, and 10% reported no difference. Results suggest the described method of application of a refrigerant as an oral topical anesthetic has a faster onset and provides similar benefit in pain reduction compared with 20% benzocaine gel. The refrigerant was easy to accomplish and well received by subjects, indicating potential for routine use in dentistry.

  17. Evaluating topic model interpretability from a primary care physician perspective.

    PubMed

    Arnold, Corey W; Oh, Andrea; Chen, Shawn; Speier, William

    2016-02-01

    Probabilistic topic models provide an unsupervised method for analyzing unstructured text. These models discover semantically coherent combinations of words (topics) that could be integrated in a clinical automatic summarization system for primary care physicians performing chart review. However, the human interpretability of topics discovered from clinical reports is unknown. Our objective is to assess the coherence of topics and their ability to represent the contents of clinical reports from a primary care physician's point of view. Three latent Dirichlet allocation models (50 topics, 100 topics, and 150 topics) were fit to a large collection of clinical reports. Topics were manually evaluated by primary care physicians and graduate students. Wilcoxon Signed-Rank Tests for Paired Samples were used to evaluate differences between different topic models, while differences in performance between students and primary care physicians (PCPs) were tested using Mann-Whitney U tests for each of the tasks. While the 150-topic model produced the best log likelihood, participants were most accurate at identifying words that did not belong in topics learned by the 100-topic model, suggesting that 100 topics provides better relative granularity of discovered semantic themes for the data set used in this study. Models were comparable in their ability to represent the contents of documents. Primary care physicians significantly outperformed students in both tasks. This work establishes a baseline of interpretability for topic models trained with clinical reports, and provides insights on the appropriateness of using topic models for informatics applications. Our results indicate that PCPs find discovered topics more coherent and representative of clinical reports relative to students, warranting further research into their use for automatic summarization. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  18. Evaluating Topic Model Interpretability from a Primary Care Physician Perspective

    PubMed Central

    Arnold, Corey W.; Oh, Andrea; Chen, Shawn; Speier, William

    2015-01-01

    Background and Objective Probabilistic topic models provide an unsupervised method for analyzing unstructured text. These models discover semantically coherent combinations of words (topics) that could be integrated in a clinical automatic summarization system for primary care physicians performing chart review. However, the human interpretability of topics discovered from clinical reports is unknown. Our objective is to assess the coherence of topics and their ability to represent the contents of clinical reports from a primary care physician’s point of view. Methods Three latent Dirichlet allocation models (50 topics, 100 topics, and 150 topics) were fit to a large collection of clinical reports. Topics were manually evaluated by primary care physicians and graduate students. Wilcoxon Signed-Rank Tests for Paired Samples were used to evaluate differences between different topic models, while differences in performance between students and primary care physicians (PCPs) were tested using Mann-Whitney U tests for each of the tasks. Results While the 150-topic model produced the best log likelihood, participants were most accurate at identifying words that did not belong in topics learned by the 100-topic model, suggesting that 100 topics provides better relative granularity of discovered semantic themes for the data set used in this study. Models were comparable in their ability to represent the contents of documents. Primary care physicians significantly outperformed students in both tasks. Conclusion This work establishes a baseline of interpretability for topic models trained with clinical reports, and provides insights on the appropriateness of using topic models for informatics applications. Our results indicate that PCPs find discovered topics more coherent and representative of clinical reports relative to students, warranting further research into their use for automatic summarization. PMID:26614020

  19. Storytelling of co-operative team meetings in acute psychiatric care.

    PubMed

    Vuokila-Oikkonen, Päivi; Janhonen, Sirpa; Saarento, Outi; Harri, Marja

    2002-10-01

    One of the goals of co-operative psychiatric nursing and co-operative team meetings is to improve patients' and significant others' participation and thus, to enhance patients' resources outside the hospital. The objective of this paper is to describe the different expert interventions that either enabled or prevented patient and his/her significant others participation in co-operative team meetings in acute psychiatric wards. The data consisted of 11 videotaped team meetings. The participants were voluntary patients, significant others and experts in health and social care. A narrative approach focused on the storytelling of all members in the meetings. The method of modified dialogue analysis was used to identify the ideas of the stories. The same topic of discussion was shared in active participation. The experts asked open-ended questions, the patient and his/her significant others' were free to express their viewpoints and the experts' interpretation was based on their stories. The experts presented the reasons for their questions, and the contents of the questions were verbalized. In passive participation, the experts questions were based on their own point of view, and the patient and his significant others merely answered these questions. If the expert opinion appeared too dominating at the co-operative team meeting, the patient's and his/her significant others' participation was in jeopardy. The physician either dominates the storytelling or gives space for free expressions of various viewpoints during the co-operative team meetings.

  20. Students' Interest in Geoscience Topics, Contexts and Methods

    ERIC Educational Resources Information Center

    Hemmer, Ingrid; Bayrhuber, Horst; Haubler, Peter; Hemmer, Michael; Hlawatsch, Sylke; Hoffmann, Lore; Raffelsiefer, Marion

    2007-01-01

    Geoscience topics are playing an increasingly important role with regard to the future of our planet. Consequently, they have been moving into the educational foreground because of their societal relevance. The question is, however: Are pupils interested in these topics? This is important didactically, for interest is both a prerequisite and a…

  1. Problematic topic transitions in dysarthric conversation.

    PubMed

    Bloch, Steven; Saldert, Charlotta; Ferm, Ulrika

    2015-01-01

    This study examined the nature of topic transition problems associated with acquired progressive dysarthric speech in the everyday conversation of people with motor neurone disease. Using conversation analytic methods, a video collection of five naturally occurring problematic topic transitions was identified, transcribed and analysed. These were extracted from a main collection of over 200 other-initiated repair sequences and a sub-set of 15 problematic topic transition sequences. The sequences were analysed with reference to how the participants both identified and resolved the problems. Analysis revealed that topic transition by people with dysarthria can prove problematic. Conversation partners may find transitions problematic not only because of speech intelligibility but also because of a sequential disjuncture between the dysarthric speech turn and whatever topic has come prior. In addition the treatment of problematic topic transition as a complaint reveals the potential vulnerability of people with dysarthria to judgements of competence. These findings have implications for how dysarthria is conceptualized and how specific actions in conversation, such as topic transition, might be suitable targets for clinical intervention.

  2. Tactile friction of topical formulations.

    PubMed

    Skedung, L; Buraczewska-Norin, I; Dawood, N; Rutland, M W; Ringstad, L

    2016-02-01

    The tactile perception is essential for all types of topical formulations (cosmetic, pharmaceutical, medical device) and the possibility to predict the sensorial response by using instrumental methods instead of sensory testing would save time and cost at an early stage product development. Here, we report on an instrumental evaluation method using tactile friction measurements to estimate perceptual attributes of topical formulations. Friction was measured between an index finger and an artificial skin substrate after application of formulations using a force sensor. Both model formulations of liquid crystalline phase structures with significantly different tactile properties, as well as commercial pharmaceutical moisturizing creams being more tactile-similar, were investigated. Friction coefficients were calculated as the ratio of the friction force to the applied load. The structures of the model formulations and phase transitions as a result of water evaporation were identified using optical microscopy. The friction device could distinguish friction coefficients between the phase structures, as well as the commercial creams after spreading and absorption into the substrate. In addition, phase transitions resulting in alterations in the feel of the formulations could be detected. A correlation was established between skin hydration and friction coefficient, where hydrated skin gave rise to higher friction. Also a link between skin smoothening and finger friction was established for the commercial moisturizing creams, although further investigations are needed to analyse this and correlations with other sensorial attributes in more detail. The present investigation shows that tactile friction measurements have potential as an alternative or complement in the evaluation of perception of topical formulations. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Topical nonsteroidal anti-inflammatory drugs for the treatment of pain due to soft tissue injury: diclofenac epolamine topical patch

    PubMed Central

    Lionberger, David R; Brennan, Michael J

    2010-01-01

    The objective of this article is to review published clinical data on diclofenac epolamine topical patch 1.3% (DETP) in the treatment of acute soft tissue injuries, such as strains, sprains, and contusions. Review of published literature on topical nonsteroidal anti-inflammatory drugs (NSAIDs), diclofenac, and DETP in patients with acute soft tissue injuries was included. Relevant literature was identified on MEDLINE using the search terms topical NSAIDs, diclofenac, diclofenac epolamine, acute pain, sports injury, soft tissue injury, strain, sprain, and contusion, and from citations in retrieved articles covering the years 1978–2008. Review of published, randomized clinical trials and meta-analyses shows that topical NSAIDs are significantly more effective than placebo in relieving acute pain; the pooled average relative benefit was 1.7 (95% confidence interval, 1.5–1.9). In a limited number of comparisons, topical and oral NSAIDs provided comparable pain relief, but the use of topical agents produced lower plasma drug concentrations and fewer systemic adverse events (AEs). The physical–chemical properties of diclofenac epolamine make it well suited for topical use. In patients with acute soft tissue injuries treated with DETP, clinical data report an analgesic benefit within hours of the first application, and significant pain relief relative to placebo within 3 days. Moreover, DETP displayed tolerability comparable with placebo; the most common AEs were pruritus and other application site reactions. Review of published literature suggests that DETP is generally safe and well tolerated, clinically efficacious, and a rational treatment option for patients experiencing acute pain associated with strains, sprains, and contusions, and other localized painful conditions. PMID:21197326

  4. Tracking Multiple Topics for Finding Interesting Articles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pon, R K; Cardenas, A F; Buttler, D J

    We introduce multiple topic tracking (MTT) for iScore to better recommend news articles for users with multiple interests and to address changes in user interests over time. As an extension of the basic Rocchio algorithm, traditional topic detection and tracking, and single-pass clustering, MTT maintains multiple interest profiles to identify interesting articles for a specific user given user-feedback. Focusing on only interesting topics enables iScore to discard useless profiles to address changes in user interests and to achieve a balance between resource consumption and classification accuracy. Also by relating a topic's interestingness to an article's interestingness, iScore is able tomore » achieve higher quality results than traditional methods such as the Rocchio algorithm. We identify several operating parameters that work well for MTT. Using the same parameters, we show that MTT alone yields high quality results for recommending interesting articles from several corpora. The inclusion of MTT improves iScore's performance by 9% to 14% in recommending news articles from the Yahoo! News RSS feeds and the TREC11 adaptive filter article collection. And through a small user study, we show that iScore can still perform well when only provided with little user feedback.« less

  5. Antimicrobial topical agents used in the vagina.

    PubMed

    Frey Tirri, Brigitte

    2011-01-01

    Vaginally applied antimicrobial agents are widely used in the vagina in women with lower genital tract infections. An 'antimicrobial' is a general term that refers to a group of drugs that are effective against bacteria, fungi, viruses and protozoa. Topical treatments can be prescribed for a wide variety of vaginal infections. Many bacterial infections, such as bacterial vaginosis, desquamative inflammatory vaginitis or, as some European authors call it, aerobic vaginitis as well as infection with Staphylococcus aureus or group A streptococci, may be treated in this way. Candida vulvovaginitis is a fungal infection that is very amenable to topical treatment. The most common viral infections which can be treated with topical medications are condylomata acuminata and herpes simplex. The most often encountered protozoal vaginitis, which is caused by Trichomonas vaginalis, may be susceptible to topical medications, although this infection is treated systemically. This chapter covers the wide variety of commonly used topical antimicrobial agents for these diseases and focuses on the individual therapeutic agents and their clinical efficacy. In addition, potential difficulties that can occur in practice, as well as the usage of these medications in the special setting of pregnancy, are described in this chapter. Copyright © 2011 S. Karger AG, Basel.

  6. Safety of topical corticosteroids in pregnancy.

    PubMed

    Chi, Ching-Chi; Wang, Shu-Hui; Wojnarowska, Fenella; Kirtschig, Gudula; Davies, Emily; Bennett, Cathy

    2015-10-26

    Topical corticosteroids are the most frequently prescribed dermatological treatment and are often used by pregnant women with skin conditions. However, little is known about their safety in pregnancy. To assess the effects of topical corticosteroids on pregnancy outcomes in pregnant women. This is an update of a review previously published in 2009. We updated our searches of the following databases to July 2015: the Cochrane Skin Group Specialised Register, the Cochrane Pregnancy and Childbirth Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL) (2015, Issue 6), MEDLINE, EMBASE, and LILACS. We also searched five trials registers and checked the reference lists of included studies, published reviews, articles that had cited the included studies, and one author's literature collection, for further references to relevant RCTs. Randomised controlled trials and cohort studies of topical corticosteroids in pregnant women, as well as case-control studies comparing maternal exposure to topical corticosteroids between cases and controls when studies reported pre-specified outcomes. The primary outcomes included mode of delivery, major congenital abnormality, birth weight, and preterm delivery (delivery before 37 completed weeks gestation); the secondary outcomes included foetal death, minor congenital abnormality, and low Apgar score (less than seven at 5 min). We used standard methodological procedures expected by Cochrane. Two authors independently applied selection criteria, extracted data, and assessed the quality of the included studies. A third author was available for resolving differences of opinion. A further author independently extracted data from included studies that were conducted by authors of this systematic review. We included 7 new observational studies in this update, bringing the total number to 14, including 5 cohort and 9 case-control studies, with 1,601,515 study subjects.Most studies found no causal associations

  7. 20th JANNAF Propulsion Systems Hazards Subcommittee Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Cocchiaro, James E. (Editor); Eggleston, Debra S. (Editor); Gannaway, Mary T. (Editor); Inzar, Jeanette M. (Editor)

    2002-01-01

    This volume, the first of two volumes, is a collection of 24 unclassified/unlimited-distribution papers which were presented at the Joint Army-Navy-NASA-Air Force (JANNAF) 20th Propulsion Systems Hazards Subcommittee (PSHS), 38th Combustion Subcommittee (CS), 26th Airbreathing Propulsion Subcommittee (APS), and 21 Modeling and Simulation Subcommittee meeting. The meeting was held 8-12 April 2002 at the Bayside Inn at The Sandestin Golf & Beach Resort and Eglin Air Force Base, Destin, Florida. Topics covered include: insensitive munitions and hazard classification testing of solid rocket motors and other munitions; vulnerability of gun propellants to impact stimuli; thermal decomposition and cookoff properties of energetic materials; burn-to-violent reaction phenomena in energetic materials; and shock-to-detonation properties of solid propellants and energetic materials.

  8. Incorporating Topics That Aren't Distance-Friendly into an Online Program: One Development Team's Experience

    ERIC Educational Resources Information Center

    Schaefer, Valentin; Doner, Sue; Pivnick, Janet

    2013-01-01

    The Native Species and Natural Processes certificate at the University of Victoria is an advanced-level online program of four courses to introduce students to state-of-the-art topics in the field of ecological restoration. The program posed some unique challenges for course developers. The development team needed to find ways to create online…

  9. Building Evidence: What Comes after an Efficacy Study? Technical Working Group Meeting. Meeting Summary (Washington, DC, October 14, 2016)

    ERIC Educational Resources Information Center

    Institute of Education Sciences, 2016

    2016-01-01

    On October 14, 2016, the National Center for Special Education Research (NCSER) and the National Center for Education Research (NCER) in the Institute of Education Sciences (IES) convened a group of experts to gain insights and advice on how best to support the advancement of evidence beyond an efficacy study. Discussion followed five topics of…

  10. PREFACE: 6th Meeting of the Spanish Neutron Scattering Association (SETN2012)

    NASA Astrophysics Data System (ADS)

    2014-11-01

    The bi-annual Meeting of the Spanish Neutron Scattering Association, VI RSETN, took place in the magnificent world heritage ancient city of Segovia, Spain, from 24-27 June 2012, at the historical building ''Palacio de Mansilla''. It was the sixth in a series of successful scientific meetings, beginning in 2002 (San Sebastián), and followed by conferences in Puerto de la Cruz (Canary Islands, 2004), Jaca (Aragón, 2006), Sant Feliú de Guixols (Cataluña, 2008) and Gijón (Asturias, 2010). The conference covered a broad range of topics related to the use of neutron scattering techniques, from soft matter and biosciences to magnetism, condensed matter as well as advanced neutron instrumentation and applications. In addition to those topics, Spanish scientists working at neutron facilities reported recent upgrades of neutron instruments. The VI RSETN was organized by a group of research scientists belonging to different institutions in Madrid: CSIC, Universidad Complutense and Universidad Politécnica de Madrid, in cooperation with the Spanish Society for Neutron Techniques (SETN, 'Sociedad Española de Técnicas Neutrónicas'). The meeting attracted around 90 participants. The total number of oral presentations was 36, including plenary and invited talks, both from domestic and foreign speakers. In addition, the number of posters was around 20. The success of the VI RSETN was due to the efforts of many colleagues involved at all stages of the meeting. We would like to thank the scientific committee, the local organizing committee, the chairs of the conference sessions as well as all the reviewers who agreed generously to help with the process. We would also like to emphasize the excellent scientific quality of all the presentations and posters, and we thank the support received from our sponsors (SETN, ICMM-CSIC, ESS-Bilbao, ILL, Carburos Metálicos), which was really important for the conference success. Finally, we hope that the readers will enjoy the 28

  11. EMSL Geochemistry, Biogeochemistry and Subsurface Science-Science Theme Advisory Panel Meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, Gordon E.; Chaka, Anne; Shuh, David K.

    2011-08-01

    This report covers the topics of discussion and the recommendations of the panel members. On December 8 and 9, 2010, the Geochemistry, Biogeochemistry, and Subsurface Science (GBSS) Science Theme Advisory Panel (STAP) convened for a more in-depth exploration of the five Science Theme focus areas developed at a similar meeting held in 2009. The goal for the fiscal year (FY) 2011 meeting was to identify potential topical areas for science campaigns, necessary experimental development needs, and scientific members for potential research teams. After a review of the current science in each of the five focus areas, the 2010 STAP discussionsmore » successfully led to the identification of one well focused campaign idea in pore-scale modeling and five longer-term potential research campaign ideas that would likely require additional workshops to identify specific research thrusts. These five campaign areas can be grouped into two categories: (1) the application of advanced high-resolution, high mass accuracy experimental techniques to elucidate the interplay between geochemistry and microbial communities in terrestrial ecosystems and (2) coupled computation/experimental investigations of the electron transfer reactions either between mineral surfaces and outer membranes of microbial cells or between the outer and inner membranes of microbial cells.« less

  12. Intelligent topical sentiment analysis for the classification of e-learners and their topics of interest.

    PubMed

    Ravichandran, M; Kulanthaivel, G; Chellatamilan, T

    2015-01-01

    Every day, huge numbers of instant tweets (messages) are published on Twitter as it is one of the massive social media for e-learners interactions. The options regarding various interesting topics to be studied are discussed among the learners and teachers through the capture of ideal sources in Twitter. The common sentiment behavior towards these topics is received through the massive number of instant messages about them. In this paper, rather than using the opinion polarity of each message relevant to the topic, authors focus on sentence level opinion classification upon using the unsupervised algorithm named bigram item response theory (BIRT). It differs from the traditional classification and document level classification algorithm. The investigation illustrated in this paper is of threefold which are listed as follows: (1) lexicon based sentiment polarity of tweet messages; (2) the bigram cooccurrence relationship using naïve Bayesian; (3) the bigram item response theory (BIRT) on various topics. It has been proposed that a model using item response theory is constructed for topical classification inference. The performance has been improved remarkably using this bigram item response theory when compared with other supervised algorithms. The experiment has been conducted on a real life dataset containing different set of tweets and topics.

  13. Review of the 25th annual scientific meeting of the International Society for Biological Therapy of Cancer.

    PubMed

    Balwit, James M; Kalinski, Pawel; Sondak, Vernon K; Coulie, Pierre G; Jaffee, Elizabeth M; Gajewski, Thomas F; Marincola, Francesco M

    2011-05-12

    Led by key opinion leaders in the field, the 25th Annual Meeting of the International Society for Biological Therapy of Cancer (iSBTc, recently renamed the Society for Immunotherapy of Cancer, SITC) provided a scientific platform for ~500 attendees to exchange cutting-edge information on basic, clinical, and translational research in cancer immunology and immunotherapy. The meeting included keynote addresses on checkpoint blockade in cancer therapy and recent advances in therapeutic vaccination against cancer induced by Human Papilloma Virus 16. Participants from 29 countries interacted through oral presentations, panel discussions, and posters on topics that included dendritic cells and cancer, targeted therapeutics and immunotherapy, innate/adaptive immune interplay in cancer, clinical trial endpoints, vaccine combinations, countering negative regulation, immune cell trafficking to tumor microenvironment, and adoptive T cell transfer. In addition to the 50 oral presentations and >180 posters on these topics, a new SITC/iSBTc initiative to create evidence-based Cancer Immunotherapy Guidelines was announced. The SITC/iSBTc Biomarkers Taskforce announced the release of recommendations on immunotherapy biomarkers and a highly successful symposium on Immuno-Oncology Biomarkers that took place on the campus of the National Institutes of Health (NIH) immediately prior to the Annual Meeting. At the Annual Meeting, the NIH took the opportunity to publicly announce the award of the U01 grant that will fund the Cancer Immunotherapy Trials Network (CITN). In summary, the Annual Meeting gathered clinicians and scientists from academia, industry, and regulatory agencies from around the globe to interact and exchange important scientific advances related to tumor immunobiology and cancer immunotherapy.

  14. Topic Repetitiveness after Traumatic Brain Injury: An Emergent, Jointly Managed Behaviour

    ERIC Educational Resources Information Center

    Body, Richard; Parker, Mark

    2005-01-01

    Topic repetitiveness is a common component of pragmatic impairment and a powerful contributor to social exclusion. Despite this, description, characterization and intervention remain underdeveloped. This article explores the nature of repetitiveness in traumatic brain injury (TBI). A case study of one individual after TBI provides the basis for a…

  15. “How Did We Get Here?”: Topic Drift in Online Health Discussions

    PubMed Central

    Hartzler, Andrea L; Huh, Jina; Hsieh, Gary; McDonald, David W; Pratt, Wanda

    2016-01-01

    Background Patients increasingly use online health communities to exchange health information and peer support. During the progression of health discussions, a change of topic—topic drift—can occur. Topic drift is a frequent phenomenon linked to incoherence and frustration in online communities and other forms of computer-mediated communication. For sensitive topics, such as health, such drift could have life-altering repercussions, yet topic drift has not been studied in these contexts. Objective Our goals were to understand topic drift in online health communities and then to develop and evaluate an automated approach to detect both topic drift and efforts of community members to counteract such drift. Methods We manually analyzed 721 posts from 184 threads from 7 online health communities within WebMD to understand topic drift, members’ reaction towards topic drift, and their efforts to counteract topic drift. Then, we developed an automated approach to detect topic drift and counteraction efforts. We detected topic drift by calculating cosine similarity between 229,156 posts from 37,805 threads and measuring change of cosine similarity scores from the threads’ first posts to their sequential posts. Using a similar approach, we detected counteractions to topic drift in threads by focusing on the irregular increase of similarity scores compared to the previous post in threads. Finally, we evaluated the performance of our automated approaches to detect topic drift and counteracting efforts by using a manually developed gold standard. Results Our qualitative analyses revealed that in threads of online health communities, topics change gradually, but usually stay within the global frame of topics for the specific community. Members showed frustration when topic drift occurred in the middle of threads but reacted positively to off-topic stories shared as separate threads. Although all types of members helped to counteract topic drift, original posters

  16. Ciclopirox Topical

    MedlinePlus

    ... Use the applicator brush attached to the bottle cap to apply ciclopirox topical solution evenly to all ... can reach these areas. Wipe off the bottle cap and neck and replace the cap tightly on ...

  17. Fluorouracil Topical

    MedlinePlus

    ... caused by years of too much exposure to sunlight). Fluorouracil cream and topical solution are also used ... plan to avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and ...

  18. The use of compound topical anesthetics: a review.

    PubMed

    Kravitz, Neal D

    2007-10-01

    The author reviewed the history of, federal regulations regarding, risks of and adverse drug reactions of five compound topical anesthetics: tetracaine, adrenaline/epinephrine and cocaine (TAC); lidocaine, adrenaline/epinephrine and tetracaine (LET); lidocaine, tetracaine and phenylephrine (TAC 20 percent Alternate); lidocaine, prilocaine and tetracaine (Profound); and lidocaine, prilocaine, tetracaine and phenylephrine with thickeners (Profound PET). The author reviewed clinical trials, case reports, descriptive articles, and U.S. Food and Drug Administration (FDA) regulations and recent public advisory warnings regarding the federal approval of and risks associated with the use of compound topical anesthetics. Compound topical anesthetics are neither FDA-regulated nor -unregulated. Some compounding pharmacies bypass the new FDA drug approval process, which is based on reliable scientific data and ensures that a marketed drug is safe, effective, properly manufactured and accurately labeled. Two deaths have been attributed to the lay use of compound topical anesthetics. In response, the FDA has announced the strengthening of its efforts against unapproved drug products. Compound topical anesthetics may be an effective alternative to local infiltration for some minimally invasive dental procedures; however, legitimate concerns exist in regard to their safety. Until they become federally regulated, compound topical anesthetics remain unapproved drug products whose benefits may not outweigh their risks for dental patients.

  19. Topical calcineurin inhibitors for atopic dermatitis: review and treatment recommendations.

    PubMed

    Carr, Warner W

    2013-08-01

    Atopic dermatitis (AD) is an inflammatory skin disease commonly affecting children and managed by pediatricians, primary care physicians, allergists, and dermatologists alike. For many years, the only available topical pharmacological treatment was topical corticosteroids. This changed in 2000-2001, when topical formulations of two calcineurin inhibitors (tacrolimus and pimecrolimus) were approved for short-term or chronic intermittent treatment of AD in patients ≥ 2 years of age, in whom other treatments have been ineffective or contraindicated. These topical calcineurin inhibitors (TCIs) quickly became a popular treatment option due at least in part to concerns over adverse events associated with prolonged topical corticosteroid use, especially in children. However, based on theoretical concerns about a possible risk of lymphoma associated with TCI use, a Boxed Warning was placed on both products in 2006. Since then, despite an extensive body of evidence, no causal relationship has been demonstrated between TCI use and an increased risk of lymphoma; however, the US FDA has concluded that a link cannot be ruled out. In fact, based on post-marketing surveillance of spontaneous, literature, and solicited reports, we report here that the lymphoma incidence in the topical pimecrolimus-exposed population is up to approximately 54-fold less than that seen in the general US population. This review summarizes the mechanism of action of TCIs, the factors that prompted the Boxed Warning, and recent TCI safety and efficacy data. Based on these data, both topical corticosteroids and TCIs should have defined roles in AD management, with TCIs favored for sensitive skin areas (e.g., face) and instances where topical corticosteroids have proven ineffective, thereby minimizing the risk of adverse effects with both drug classes.

  20. Armenian media coverage of science topics

    NASA Astrophysics Data System (ADS)

    Mkhitaryan, Marie

    2016-12-01

    The article discusses features and issues of Armenian media coverage on scientific topics and provides recommendations on how to promote scientific topics in media. The media is more interested in social or public reaction rather than in scientific information itself. Medical science has a large share of the global media coverage. It is followed by articles about environment, space, technology, physics and other areas. Armenian media mainly tends to focus on a scientific topic if at first sight it contains something revolutionary. Media primarily reviews whether that scientific study can affect the Armenian economy and only then decides to refer to it. Unfortunately, nowadays the perception of science is a little distorted in media. We can often see headlines of news where is mentioned that the scientist has made "an invention". Nowadays it is hard to see the border between a scientist and an inventor. In fact, the technological term "invention" attracts the media by making illusionary sensation and ensuring large audience. The report also addresses the "Gitamard" ("A science-man") special project started in 2016 in Mediamax that tells about scientists and their motivations.

  1. Topical, Yes, but It Dives beneath the Surface

    ERIC Educational Resources Information Center

    Tyler, Paul

    2017-01-01

    Topical science is about developing an awareness of science issues in the news and the importance of science stories that affect pupils' lives and the world around them. It is about making science relevant for pupils and engaging them in the subject. The author explores how children can be engaged and inspired through topical science. The idea of…

  2. Regenerative Medicine Will Make Orthopaedic Implants Obsolete In Our Time Orthopaedic Research Society First Annual Meeting Debate, San Diego, March 21st , 2017.

    PubMed

    Johnstone, Brian; Jacobs, Joshua J; Sandell, Linda J; Wilkinson, J Mark

    2018-05-10

    The mission of the Orthopaedic Research Society is to promote and advance musculoskeletal research worldwide. With this in mind, the Annual Meeting Program Committee sought to establish a debate as a key component of the meeting. Our purpose was to provoke discussion on topics that are core to our mission and to engage all constituencies within the society by examining questions of broad relevance. To this end, the topic "Regenerative medicine will make orthopaedic implants obsolete in our time" was selected as the title of the inaugural debate. The arguments for and against the motion are presented in this perspectives article. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  3. Proceedings of the 1994 international meeting on reduced enrichment for research and test reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-08-01

    This meeting brought together participants in the international effort to minimize and eventually eliminate the use of highly enriched uranium in civilian nuclear programs. Papers cover the following topics: National programs; fuel cycle; nuclear fuels; analyses; advanced reactors; and reactor conversions. Selected papers have been indexed separately for inclusion to the Energy Science and Technology Database.

  4. Raising the Bar: Standards and Tests in California's High Schools. A Town Hall Meeting.

    ERIC Educational Resources Information Center

    Arnstine, Barbara; Futernick, Ken; Hodson, Timothy A.; Ostgaard, Kolleen

    In 1999, the LegiSchool Project planned to conduct the 12th in its series of televised Town Hall Meetings to provide a forum in which California high school students, educators, and legislators can engage in face-to-face dialogue about problems of mutual interest. For 1999, the topic is standards and tests in California high schools. This guide…

  5. Summary of the 9th annual meeting of the Italian Society for Virology.

    PubMed

    Salata, Cristiano; Calistri, Arianna; Parolin, Cristina; Palù, Giorgio

    2011-01-01

    The 9th annual meeting of the Italian Society for Virology (SIV) comprised seven plenary sessions focused on: General virology and viral genetics; Virus-Host interaction and pathogenesis; Viral oncology; Emerging viruses and zoonotic, foodborne, and environmental pathways of transmission; Viral immunology and vaccines; Medical virology and antiviral therapy; Viral biotechnologies and gene therapy. Moreover, four hot topics were discussed in special lectures: the Pioneer in human virology lecture regarding the control of viral epidemics with particular emphasis on the human immunodeficiency virus (HIV), the Pioneer in plant virology lecture focused on cell responses to plant virus infection, a Keynote lecture on the epidemiology and genetic diversity of Crimea-Congo Hemorrhagic Fever virus, and the G.B. Rossi lecture on the molecular basis and clinical implications of human cytomegalovirus tropism for endothelial/epithelial cells. The meeting had an attendance of about 160 virologists. A summary of the plenary lectures and oral selected presentations is reported.

  6. The Turn-on of LCLS: the X-Ray Free Electron Laser at SLAC ( Keynote - 2011 JGI User Meeting)

    ScienceCinema

    Drell, Persis [SLAC National Accelerator Lab., Menlo Park, CA (United States)

    2018-06-15

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. SLAC National Laboratory Director Persis Drell gives a keynote talk on "The Turn-on of LCLS: the X-Ray Free-Electron Laser at SLAC" at the 6th Genomics of Energy & Environment Meeting on March 22, 2011

  7. Association Genetics of Populus trichocarpa or Resequencing in Populus: Towards Genome Wide Association Genetics (2011 JGI User Meeting)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tuskan, Gerry

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Gerry Tuskan of Oak Ridge National Laboratory on Resequencing in Populus: Towards Genome Wide Association Geneticsmore » at the 6th annual Genomics of Energy Environment Meeting on March 23, 2011.« less

  8. Topical fluoride for caries prevention

    PubMed Central

    Weyant, Robert J.; Tracy, Sharon L.; Anselmo, Theresa (Tracy); Beltrán-Aguilar, Eugenio D.; Donly, Kevin J.; Frese, William A.; Hujoel, Philippe P.; Iafolla, Timothy; Kohn, William; Kumar, Jayanth; Levy, Steven M.; Tinanoff, Norman; Wright, J. Timothy; Zero, Domenick; Aravamudhan, Krishna; Frantsve-Hawley, Julie; Meyer, Daniel M.

    2015-01-01

    Background A panel of experts convened by the American Dental Association (ADA) Council on Scientific Affairs presents evidence-based clinical recommendations regarding professionally applied and prescription-strength, home-use topical fluoride agents for caries prevention. These recommendations are an update of the 2006 ADA recommendations regarding professionally applied topical fluoride and were developed by using a new process that includes conducting a systematic review of primary studies. Types of Studies Reviewed The authors conducted a search of MEDLINE and the Cochrane Library for clinical trials of professionally applied and prescription-strength topical fluoride agents—including mouthrinses, varnishes, gels, foams and pastes—with caries increment outcomes published in English through October 2012. Results The panel included 71 trials from 82 articles in its review and assessed the efficacy of various topical fluoride caries-preventive agents. The panel makes recommendations for further research. Practical Implications The panel recommends the following for people at risk of developing dental caries: 2.26 percent fluoride varnish or 1.23 percent fluoride (acidulated phosphate fluoride) gel, or a prescription-strength, home-use 0.5 percent fluoride gel or paste or 0.09 percent fluoride mouthrinse for patients 6 years or older. Only 2.26 percent fluoride varnish is recommended for children younger than 6 years. The strengths of the recommendations for the recommended products varied from “in favor” to “expert opinion for.” As part of the evidence-based approach to care, these clinical recommendations should be integrated with the practitioner's professional judgment and the patient's needs and preferences. PMID:24177407

  9. 78 FR 13374 - Notice of Public Meetings: Sierra Front-Northwestern Great Basin Resource Advisory Council, Nevada

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-27

    ... public land management in Nevada. Topics for discussion at each meeting will include, but are not limited... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLNVS00000 L12200000.PM0000 LXSS006F0000... Basin Resource Advisory Council, Nevada AGENCY: Bureau of Land Management, Interior. ACTION: Notice of...

  10. The extinction of topical erythromycin therapy for acne vulgaris and concern for the future of topical clindamycin.

    PubMed

    Austin, Brett A; Fleischer, Alan B

    2017-03-01

    This study aims to evaluate changes in topical antibiotic prescribing trends for acne. We retrospectively reviewed the National Ambulatory Medical Care Survey data from 1993 to 2012 for all visits in which acne vulgaris was the primary diagnosis. Acne vulgaris represented an estimated 94.5 million (92.3, 96.8) visits during the 20-year study period. Bivariate analysis showed that over time erythromycin use declined (p < 0.001) and clindamycin use rose (p = 0.10). Multivariate analysis showed that the likelihood of erythromycin use declined to near zero (p < 0.001), whereas clindamycin utilization increased (p < 0.05). PubMed searches of "erythromycin AND resistance" and "clindamycin AND resistance" demonstrated increasing publication frequency by year, fit with sigmoidal functions (erythromycin: R 2  =   0.93 and clindamycin: R 2  =   0.94). Yearly publications consistently exceeded 100 papers for erythromycin and clindamycin resistance in 1983 and 2003, respectively, roughly corresponding to the interval between reports of their utility in acne. Our findings suggest topical erythromycin use for acne has essentially ceased. By contrast, clindamycin use is increasing. Current recommendations discourage topical antibiotic monotherapy in favor of combination therapy with benzoyl peroxide and topical retinoids. Our group's previous work demonstrated that this trend is indeed occurring.

  11. Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a vascular endothelial growth factor inhibitor.

    PubMed

    Cohen, Philip R

    2017-04-01

    Melasma is an acquired disorder of pigmentation that presents with asymptomatic symmetric darkening of the face. The pathogenesis of this condition is multifactorial and influenced by several factors including female sex hormones, genetic predisposition and ultraviolet light exposure. The management of melasma is usually directed at more than one of the causative etiologic factors and often incorporates a combination of topical agents, with or without the addition of physical modalities. Estrogen and angiogenesis are significant factors in the etiology of melasma. A useful addition to the therapeutic armentarium for treating melasma would include a topical agent that could effect both of these causative factors. Specifically, a topical preparation consisting of an anti-estrogen and a vascular endothelial growth factor inhibitor would accomplish this goal. Suitable candidates that target estrogen receptors and vascular endothelial growth factor are currently used in medical oncology as systemic antineoplastic agents. The anti-estrogen could be either a selective estrogen receptor modulator (such as tamoxifen or raloxifene) or an aromatase inhibitor (such as anastrozole or letrozole or exemestane). The vascular endothelial growth factor inhibitor would be bevacizumab. In conclusion, a novel-topically administered-therapy for melasma would combine an anti-estrogen and a vascular endothelial growth factor inhibitor. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. JANNAF 28th Propellant Development and Characterization Subcommittee and 17th Safety and Environmental Protection Subcommittee Joint Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Cocchiaro, James E. (Editor); Mulder, Edwin J. (Editor); Gomez-Knight, Sylvia J. (Editor)

    1999-01-01

    This volume contains 37 unclassified/unlimited-distribution technical papers that were presented at the JANNAF 28th Propellant Development & Characterization Subcommittee (PDCS) and 17th Safety & Environmental Protection Subcommittee (S&EPS) Joint Meeting, held 26-30 April 1999 at the Town & Country Hotel and the Naval Submarine Base, San Diego, California. Volume II contains 29 unclassified/limited-distribution papers that were presented at the 28th PDCS and 17th S&EPS Joint Meeting. Volume III contains a classified paper that was presented at the 28th PDCS Meeting on 27 April 1999. Topics covered in PDCS sessions include: solid propellant rheology; solid propellant surveillance and aging; propellant process engineering; new solid propellant ingredients and formulation development; reduced toxicity liquid propellants; characterization of hypergolic propellants; and solid propellant chemical analysis methods. Topics covered in S&EPS sessions include: space launch range safety; liquid propellant hazards; vapor detection methods for toxic propellant vapors and other hazardous gases; toxicity of propellants, ingredients, and propellant combustion products; personal protective equipment for toxic liquid propellants; and demilitarization/treatment of energetic material wastes.

  13. Introduction of an all-electronic administrative process for a major international pediatric surgical meeting.

    PubMed

    Applebaum, Harry; Boles, Kay; Atkinson, James B

    2003-12-01

    The administrative process for annual meetings is time consuming and increasingly costly when accomplished by traditional postal, fax, and telephone methods. The Pacific Association of Pediatric Surgeons introduced an all-electronic communication format for its 2002 annual meeting. Attendee acceptance and administrative and financial impact were evaluated. Interested physicians were directed to a Website containing detailed information and electronic forms. E-mail was used for the abstract selection and manuscript submission processes. Attendees were surveyed to evaluate the new format. Administrative costs for the new format were compared with estimated costs for a comparable traditionally managed meeting. Attendance was similar to that at previous US meetings. Eighty-two percent of respondents approved of the all-electronic format, although 48% believed a choice should remain. None suggested a complete return to the traditional format. Abstract and manuscript processing time was reduced substantially as were administrative costs (79.43 dollars savings per physician registrant). Adoption of an all-electronic annual meeting administrative process was associated with substantial cost reduction, increased efficiency, and excellent attendee satisfaction. This technology can help avoid increased registration fees while easing the burden on physician volunteers.

  14. Topical Acne Treatments and Pregnancy

    MedlinePlus

    ... are benzoyl peroxide, azelaic acid, glycolic acid, and salicylic acid. Prescription acne medications include tretinoin, adapalene, dapsone, and ... ACOG) recommends topical benzoyl peroxide, azelaic acid, topical salicylic acid and glycolic acid for treatment of acne in ...

  15. Doha agreement meeting on terminology and definitions in groin pain in athletes.

    PubMed

    Weir, Adam; Brukner, Peter; Delahunt, Eamonn; Ekstrand, Jan; Griffin, Damian; Khan, Karim M; Lovell, Greg; Meyers, William C; Muschaweck, Ulrike; Orchard, John; Paajanen, Hannu; Philippon, Marc; Reboul, Gilles; Robinson, Philip; Schache, Anthony G; Schilders, Ernest; Serner, Andreas; Silvers, Holly; Thorborg, Kristian; Tyler, Timothy; Verrall, Geoffrey; de Vos, Robert-Jan; Vuckovic, Zarko; Hölmich, Per

    2015-06-01

    Heterogeneous taxonomy of groin injuries in athletes adds confusion to this complicated area. The 'Doha agreement meeting on terminology and definitions in groin pain in athletes' was convened to attempt to resolve this problem. Our aim was to agree on a standard terminology, along with accompanying definitions. A one-day agreement meeting was held on 4 November 2014. Twenty-four international experts from 14 different countries participated. Systematic reviews were performed to give an up-to-date synthesis of the current evidence on major topics concerning groin pain in athletes. All members participated in a Delphi questionnaire prior to the meeting. Unanimous agreement was reached on the following terminology. The classification system has three major subheadings of groin pain in athletes: 1. Defined clinical entities for groin pain: Adductor-related, iliopsoas-related, inguinal-related and pubic-related groin pain. 2. Hip-related groin pain. 3. Other causes of groin pain in athletes. The definitions are included in this paper. The Doha agreement meeting on terminology and definitions in groin pain in athletes reached a consensus on a clinically based taxonomy using three major categories. These definitions and terminology are based on history and physical examination to categorise athletes, making it simple and suitable for both clinical practice and research. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  16. Abstracts and program proceedings of the 1994 meeting of the International Society for Ecological Modelling North American Chapter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kercher, J.R.

    1994-06-01

    This document contains information about the 1994 meeting of the International Society for Ecological Modelling North American Chapter. The topics discussed include: extinction risk assessment modelling, ecological risk analysis of uranium mining, impacts of pesticides, demography, habitats, atmospheric deposition, and climate change.

  17. Detecting Hotspot Information Using Multi-Attribute Based Topic Model

    PubMed Central

    Wang, Jing; Li, Li; Tan, Feng; Zhu, Ying; Feng, Weisi

    2015-01-01

    Microblogging as a kind of social network has become more and more important in our daily lives. Enormous amounts of information are produced and shared on a daily basis. Detecting hot topics in the mountains of information can help people get to the essential information more quickly. However, due to short and sparse features, a large number of meaningless tweets and other characteristics of microblogs, traditional topic detection methods are often ineffective in detecting hot topics. In this paper, we propose a new topic model named multi-attribute latent dirichlet allocation (MA-LDA), in which the time and hashtag attributes of microblogs are incorporated into LDA model. By introducing time attribute, MA-LDA model can decide whether a word should appear in hot topics or not. Meanwhile, compared with the traditional LDA model, applying hashtag attribute in MA-LDA model gives the core words an artificially high ranking in results meaning the expressiveness of outcomes can be improved. Empirical evaluations on real data sets demonstrate that our method is able to detect hot topics more accurately and efficiently compared with several baselines. Our method provides strong evidence of the importance of the temporal factor in extracting hot topics. PMID:26496635

  18. Lecture Notes on Topics in Accelerator Physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chao, Alex W.

    These are lecture notes that cover a selection of topics, some of them under current research, in accelerator physics. I try to derive the results from first principles, although the students are assumed to have an introductory knowledge of the basics. The topics covered are: (1) Panofsky-Wenzel and Planar Wake Theorems; (2) Echo Effect; (3) Crystalline Beam; (4) Fast Ion Instability; (5) Lawson-Woodward Theorem and Laser Acceleration in Free Space; (6) Spin Dynamics and Siberian Snakes; (7) Symplectic Approximation of Maps; (8) Truncated Power Series Algebra; and (9) Lie Algebra Technique for nonlinear Dynamics. The purpose of these lectures ismore » not to elaborate, but to prepare the students so that they can do their own research. Each topic can be read independently of the others.« less

  19. The Repeated Name Penalty, the Overt Pronoun Penalty, and Topic in Japanese.

    PubMed

    Shoji, Shinichi; Dubinsky, Stanley; Almor, Amit

    2017-02-01

    When reading sentences with an anaphoric reference to a subject antecedent, repeated-name anaphors result in slower reading times relative to pronouns (the Repeated Name Penalty: RNP), and overt pronouns are read slower than null pronouns (the Overt Pronoun Penalty: OPP). Because in most languages previously tested, the grammatical subject is typically also the discourse topic it remains unclear whether these effects reflect anaphors' subject-hood or their topic-hood. To address this question we conducted a self-paced reading experiment in Japanese, a language which morphologically marks both subjects and topics overtly. Our results show that both repeated-name topic-subject anaphors and repeated-name non-topic-subject anaphors exhibit the RNP and that both overt-pronoun topic-subject and overt-pronoun non-topic-subject anaphors show the OPP. However, a detailed examination of performance revealed an interaction between the anaphor topic marking, reference form, and the antecedent's grammatical status, indicating that the effect of the antecedent's grammatical status is strongest for null pronoun and repeated name subject anaphors and that the overt form most similar to null pronouns is the repeated name topic anaphor. We discuss the implications of these findings for theories of anaphor processing.

  20. Evaluating an Organizational Protocol to Implement Effective Leadership Meetings

    ERIC Educational Resources Information Center

    Anderson, Erika

    2009-01-01

    The problem on which this study focused was the need to organize and implement effective leadership meetings that led to improved professional collaboration. The purpose was to evaluate the use of a protocol in organizing and implementing such meetings. The research questions were framed around the four levels of the Kirkpatrick (1996) evaluation…