Migration, Knowledge Transfer, and the Emergence of Australian Post-War Skiing: The Story of Charles William Anton

PubMed Central

Strobl, Philipp

2016-01-01

Abstract Skiing underwent substantial changes during the post-war years when the sport turned into a multi-billion dollar industry and a leisure activity for the masses. Despite its global nature and popularity, skiing in academic writing has not gained much recognition. This paper explores the role of knowledge transfer during the pioneering phase of post-war skiing in Australia. It describes the life of Charles William Anton, an Austrian refugee from the Anschluss who migrated to Sydney and subsequently became one of the founding fathers of Australian post-war skiing. The following pages show the multi-layered nature of skiing as a global sport by exemplifying how ideas spread from pre-war Europe to post-war Australia. The paper will also provide a case study about refugee knowledge transfer and the ‘productive process of absorption, adoption or rejection of knowledge’ that takes place once an idea has been introduced into a new environment. PMID:29170603

Migration, Knowledge Transfer, and the Emergence of Australian Post-War Skiing: The Story of Charles William Anton.

PubMed

Strobl, Philipp

2016-11-01

Skiing underwent substantial changes during the post-war years when the sport turned into a multi-billion dollar industry and a leisure activity for the masses. Despite its global nature and popularity, skiing in academic writing has not gained much recognition. This paper explores the role of knowledge transfer during the pioneering phase of post-war skiing in Australia. It describes the life of Charles William Anton, an Austrian refugee from the Anschluss who migrated to Sydney and subsequently became one of the founding fathers of Australian post-war skiing. The following pages show the multi-layered nature of skiing as a global sport by exemplifying how ideas spread from pre-war Europe to post-war Australia. The paper will also provide a case study about refugee knowledge transfer and the 'productive process of absorption, adoption or rejection of knowledge' that takes place once an idea has been introduced into a new environment.

Association football and the representation of homosexuality by the print media: a case study of Anton Hysén.

PubMed

Cleland, Jamie

2014-01-01

In March 2011, Anton Hysén (a semiprofessional footballer currently playing in the Swedish fourth division) became only the second association football (soccer) player of any professional disposition to publicly declare his homosexuality while still playing the game. This article provides a textual analysis of the print media's reaction to Hysén coming out and examines whether, in 2011, they portray more inclusive notions toward homosexuality than they did in 1990 when British footballer Justin Fashanu came out. The results advance inclusive masculinity theory as a number of print media sources (mostly British) interview Hysén in the weeks immediately after he came out and publish articles that challenge homophobia. Highlighting a change since 1990, a significant number of articles stress the need for the key stakeholders in football (players, fans, clubs, agents, the authorities, and the media) to accept gay players.

[The attempts at drug therapy of cancer by Anton Störck (1731-1803). History of experimental pharmacology in the old Vienna Medical School].

PubMed

Schweppe, K W; Probst, C

1982-03-15

The essay deals with the development of medical research in Vienna - especially the development of therapeutic drugs. This progress is related to the philosophical, historical, and political background of the enlightened absolutism and the reformatory efforts of van Swieten during the regency of Maria Theresia in Austria. Anton Störck's research on hemlock (Conium maculatum) is used as an example. The method of Störck's research-work is described. Furthermore it is demonstrated to what extent Störck's data, deduced from empirical examinations, are integrated in the official medical system, i.e. Boerhaave's iatromechanic system. Finally the attempt is made to correlate these processes of medical history with the scientific-historical model of Thomas Kuhn.

Benthic Assemblages of the Anton Dohrn Seamount (NE Atlantic): Defining Deep-Sea Biotopes to Support Habitat Mapping and Management Efforts with a Focus on Vulnerable Marine Ecosystems.

PubMed

Davies, Jaime S; Stewart, Heather A; Narayanaswamy, Bhavani E; Jacobs, Colin; Spicer, John; Golding, Neil; Howell, Kerry L

2015-01-01

In 2009 the NW and SE flanks of Anton Dohrn Seamount were surveyed using multibeam echosounder and video ground-truthing to characterise megabenthic biological assemblages (biotopes) and assess those which clearly adhere to the definition of Vulnerable Marine Ecosystems, for use in habitat mapping. A combination of multivariate analysis of still imagery and video ground-truthing defined 13 comprehensive descriptions of biotopes that function as mapping units in an applied context. The data reveals that the NW and SE sides of Anton Dohrn Seamount (ADS) are topographically complex and harbour diverse biological assemblages, some of which agree with current definitions of 'listed' habitats of conservation concern. Ten of these biotopes could easily be considered Vulnerable Marine Ecosystems; three coral gardens, four cold-water coral reefs, two xenophyophore communities and one sponge dominated community, with remaining biotopes requiring more detailed assessment. Coral gardens were only found on positive geomorphic features, namely parasitic cones and radial ridges, found both sides of the seamount over a depth of 1311-1740 m. Two cold-water coral reefs (equivalent to summit reef) were mapped on the NW side of the seamount; Lophelia pertusa reef associated with the cliff top mounds at a depth of 747-791 m and Solenosmilia variabilis reef on a radial ridge at a depth of 1318-1351 m. Xenophyophore communities were mapped from both sides of the seamount at a depth of 1099-1770 m and were either associated with geomorphic features or were in close proximity (< 100 m) to them. The sponge dominated community was found on the steep escarpment either side of the seamount over at a depth of 854-1345 m. Multivariate diversity revealed the xenophyophore biotopes to be the least diverse, and a hard substratum biotope characterised by serpulids and the sessile holothurian, Psolus squamatus, as the most diverse.

Benthic Assemblages of the Anton Dohrn Seamount (NE Atlantic): Defining Deep-Sea Biotopes to Support Habitat Mapping and Management Efforts with a Focus on Vulnerable Marine Ecosystems

PubMed Central

Davies, Jaime S.; Stewart, Heather A.; Narayanaswamy, Bhavani E.; Jacobs, Colin; Spicer, John; Golding, Neil; Howell, Kerry L.

2015-01-01

In 2009 the NW and SE flanks of Anton Dohrn Seamount were surveyed using multibeam echosounder and video ground-truthing to characterise megabenthic biological assemblages (biotopes) and assess those which clearly adhere to the definition of Vulnerable Marine Ecosystems, for use in habitat mapping. A combination of multivariate analysis of still imagery and video ground-truthing defined 13 comprehensive descriptions of biotopes that function as mapping units in an applied context. The data reveals that the NW and SE sides of Anton Dohrn Seamount (ADS) are topographically complex and harbour diverse biological assemblages, some of which agree with current definitions of ‘listed’ habitats of conservation concern. Ten of these biotopes could easily be considered Vulnerable Marine Ecosystems; three coral gardens, four cold-water coral reefs, two xenophyophore communities and one sponge dominated community, with remaining biotopes requiring more detailed assessment. Coral gardens were only found on positive geomorphic features, namely parasitic cones and radial ridges, found both sides of the seamount over a depth of 1311–1740 m. Two cold-water coral reefs (equivalent to summit reef) were mapped on the NW side of the seamount; Lophelia pertusa reef associated with the cliff top mounds at a depth of 747–791 m and Solenosmilia variabilis reef on a radial ridge at a depth of 1318-1351 m. Xenophyophore communities were mapped from both sides of the seamount at a depth of 1099–1770 m and were either associated with geomorphic features or were in close proximity (< 100 m) to them. The sponge dominated community was found on the steep escarpment either side of the seamount over at a depth of 854-1345 m. Multivariate diversity revealed the xenophyophore biotopes to be the least diverse, and a hard substratum biotope characterised by serpulids and the sessile holothurian, Psolus squamatus, as the most diverse. PMID:25992572

Applicability of rapid and on-site measured enzyme activity for surface water quality monitoring in an agricultural catchment

NASA Astrophysics Data System (ADS)

Stadler, Philipp; Farnleitner, Andreas H.; Sommer, Regina; Kumpan, Monika; Zessner, Matthias

2014-05-01

For the near real time and on-site detection of microbiological fecal pollution of water, the measurement of beta-D- Glucuronidase (GLUC) enzymatic activity has been suggested as a surrogate parameter and has been already successfully operated for water quality monitoring of ground water resources (Ryzinska-Paier et al. 2014). Due to possible short measure intervals of three hours, this method has high potential as a water quality monitoring tool. While cultivation based standard determination takes more than one working day (Cabral 2010) the potential advantage of detecting the GLUC activity is the high temporal measuring resolution. Yet, there is still a big gap of knowledge on the fecal indication capacity of GLUC (specificity, sensitivity, persistence, etc.) in relation to potential pollution sources and catchment conditions (Cabral 2010, Ryzinska-Paier et al. 2014). Furthermore surface waters are a big challenge for automated detection devices in a technical point of view due to the high sediment load during event conditions. This presentation shows results gained form two years of monitoring in an experimental catchment (HOAL) dominated by agricultural land use. Two enzymatic measurement devices are operated parallel at the catchment outlet to test the reproducibility and precision of the method. Data from continuous GLUC monitoring under both base flow and event conditions is compared with reference samples analyzed by standardized laboratory methods for fecal pollution detection (e.g. ISO 16649-1, Colilert18). It is shown that rapid enzymatic on-site GLUC determination can successfully be operated from a technical point of view for surface water quality monitoring under the observed catchment conditions. The comparison of enzyme activity with microbiological standard analytics reveals distinct differences in the dynamic of the signals during event conditions. Cabral J. P. S. (2010) "Water Microbiology. Bacterial Pathogens and Water" International Journal of

Cellulose, Chitosan, and Keratin Composite Materials. Controlled Drug Release

PubMed Central

2015-01-01

A method was developed in which cellulose (CEL) and/or chitosan (CS) were added to keratin (KER) to enable [CEL/CS+KER] composites to have better mechanical strength and wider utilization. Butylmethylimmidazolium chloride ([BMIm+Cl–]), an ionic liquid, was used as the sole solvent, and because the [BMIm+Cl–] used was recovered, the method is green and recyclable. Fourier transform infrared spectroscopy results confirm that KER, CS, and CEL remain chemically intact in the composites. Tensile strength results expectedly show that adding CEL or CS into KER substantially increases the mechanical strength of the composites. We found that CEL, CS, and KER can encapsulate drugs such as ciprofloxacin (CPX) and then release the drug either as a single or as two- or three-component composites. Interestingly, release rates of CPX by CEL and CS either as a single or as [CEL+CS] composite are faster and independent of concentration of CS and CEL. Conversely, the release rate by KER is much slower, and when incorporated into CEL, CS, or CEL+CS, it substantially slows the rate as well. Furthermore, the reducing rate was found to correlate with the concentration of KER in the composites. KER, a protein, is known to have secondary structure, whereas CEL and CS exist only in random form. This makes KER structurally denser than CEL and CS; hence, KER releases the drug slower than CEL and CS. The results clearly indicate that drug release can be controlled and adjusted at any rate by judiciously selecting the concentration of KER in the composites. Furthermore, the fact that the [CEL+CS+KER] composite has combined properties of its components, namely, superior mechanical strength (CEL), hemostasis and bactericide (CS), and controlled drug release (KER), indicates that this novel composite can be used in ways which hitherto were not possible, e.g., as a high-performance bandage to treat chronic and ulcerous wounds. PMID:25548871

IN MEMORIAM: Hermann Anton Haus, 1925 2003

NASA Astrophysics Data System (ADS)

2004-08-01

Photograph Hermann Anton Haus, an Institute Professor at the Massachusetts Institute of Technology (MIT), was to have been a Keynote Speaker at the Fluctuations and Noise in Photonics and Quantum Optics Conference, from which the papers in this special issue derive. Sadly, on May 21, 2003 - less than two weeks before the conference - Professor Haus succumbed to a heart attack after arriving home in Lexington, Massachusetts, from his regular, 15-mile commute by bicycle from MIT. He was 77. Throughout his lengthy and illustrious career, Professor Haus had repeatedly and very successfully addressed problems of fluctuations and noise, with special focus on the fundamental issues that arise in quantum optics. To honour Professor Haus' legacy to our technical community, this special issue of Journal of Optics B: Quantum and Semiclassical Optics is dedicated to his memory. Professor Haus was born in Ljubljana, Slovenia, in the former Yugoslavia, on 8 August 1925. After attending the Technische Hochschule, Graz, and the Technische Hochschule, Wien, in Austria, he received his Bachelor of Science degree from Union College in Schenectady, New York in 1949. In 1951, he graduated from Rensselaer Polytechnic Institute with a Master of Science in Electrical Engineering, and came to MIT, where he earned his Doctorate of Science and joined the faculty in 1954. He was promoted to Associate Professor in 1958, to Professor in 1962, and to Elihu Thomson Professor in 1973. In 1986, he was conferred the honour of Institute Professor. Professor Haus had a lifelong fascination with noise. While still an undergraduate at Union College, he became aware of Norbert Wiener's theories of statistical phenomena - the new mathematics needed to understand and quantify the random fluctuations we refer to as noise. So it was that noise theory formed the core of Professor Haus' research during the 1950s: noise in electron beams, noise in microwave amplifiers, and noise in amplifier cascades. Two of

jsc2017e136101 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 crewmembers Norishige Kanai of the Japan Aerospace Agency (JAXA, left), Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos, center) and Scott Tin

NASA Image and Video Library

2017-12-04

jsc2017e136101 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 crewmembers Norishige Kanai of the Japan Aerospace Agency (JAXA, left), Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos, center) and Scott Tingle of NASA (right) answer reporters’ questions Dec. 4 prior to their departure for their launch site at the Baikonur Cosmodrome in Kazakhstan. They are scheduled to launch Dec. 17 on the Soyuz MS-07 spacecraft for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

Preliminary study of the antioxidant properties of flowers and roots of Pyrostegia venusta (Ker Gawl) Miers.

PubMed

Roy, Purabi; Amdekar, Sarika; Kumar, Avnish; Singh, Vinod

2011-08-23

Free radical stress leads to tissue injury and can eventually to arthritis, atherosclerosis, diabetes mellitus, neurodegenerative diseases and carcinogenesis. Several studies are ongoing worldwide to find natural antioxidants of plant origin. We assessed the in-vitro antioxidant activities and screened the phytochemical constituents of methanolic extracts of Pyrostegia venusta (Ker Gawl) Miers. We evaluated the antioxidant potential and phytochemical constituents of P. venusta using 1,1-Diphenyl-2-picrylhydrazyl (DPPH), 2, 2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) and ferric reducing antioxidant power (FRAP) assays. Gas chromatography-mass spectroscopy (GC-MS) studies were also undertaken to assess the phytochemical composition of the flower extracts. Phytochemical analyses revealed the presence of terpenoids, alkaloids, tannins, steroids, and saponins. The reducing ability of both extracts was in the range (in μm Fe(II)/g) of 112.49-3046.98 compared with butylated hydroxytoluene (BHT; 63.56 ± 2.62), catechin (972.02 ± 0.72 μm) and quercetin 3208.27 ± 31.29. A significant inhibitory effect of extracts of flowers (IC50 = 0.018 ± 0.69 mg/ml) and roots (IC50 = 0.026 ± 0.94 mg/ml) on ABTS free radicals was detected. The antioxidant activity of the extracts of flowers (95%) and roots (94%) on DPPH radicals was comparable with that of ascorbic acid (98.9%) and BHT (97.6%). GC-MS study revealed the presence of myoinositol, hexadecanoic acid, linoleic acid, palmitic acid and oleic acid in the flower extracts. These data suggest that P. venusta is a natural source of antioxidants. The extracts of flowers and roots of P. venusta contain significant amounts of phytochemicals with antioxidative properties and could serve as inhibitors or scavengers of free radicals. P. venusta could be exploited as a potential source for plant-based pharmaceutical products. These results could form a sound basis for further investigation in the potential discovery of new

jsc2017e136052 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 prime crewmember Scott Tingle of NASA listens to a reporter’s question during a crew news conference Nov. 30. Tingle, Anton Shkaplerov of the Russian Federa

NASA Image and Video Library

2017-11-30

jsc2017e136052 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 prime crewmember Scott Tingle of NASA listens to a reporter’s question during a crew news conference Nov. 30. Tingle, Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos), and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA), will launch Dec. 17 on the Soyuz MS-07 spacecraft from the Baikonur Cosmodrome in Kazakhstan for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center..

jsc2017e136054 - On a snowy night at Red Square in Moscow, Expedition 54-55 crewmember Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) lays flowers at the Kremlin Wall where Russian space icons are interred in traditional pre-launch cerem

NASA Image and Video Library

2017-11-30

jsc2017e136054 - On a snowy night at Red Square in Moscow, Expedition 54-55 crewmember Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) lays flowers at the Kremlin Wall where Russian space icons are interred in traditional pre-launch ceremonies Nov. 30. Shkaplerov, Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) and Scott Tingle of NASA will launch from the Baikonur Cosmodrome in Kazakhstan on the Soyuz MS-07 spacecraft Dec. 17 for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

jsc2017e136059 - On a snowy night at Red Square in Moscow, Expedition 54-55 crewmembers Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos, left), Scott Tingle of NASA (center) and Norishige Kanai of the Japan Aerospace Exploration Agency (JA

NASA Image and Video Library

2017-11-30

jsc2017e136059 - On a snowy night at Red Square in Moscow, Expedition 54-55 crewmembers Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos, left), Scott Tingle of NASA (center) and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA, right) pose for pictures in front of St. Basil’s Cathedral in traditional pre-launch ceremonies Nov. 30. They will launch from the Baikonur Cosmodrome in Kazakhstan on the Soyuz MS-07 spacecraft Dec. 17 for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

In vivo antioxidative property, antimicrobial and wound healing activity of flower extracts of Pyrostegia venusta (Ker Gawl) Miers.

PubMed

Roy, Purabi; Amdekar, Sarika; Kumar, Avnish; Singh, Rambir; Sharma, Poonam; Singh, Vinod

2012-03-06

Pyrostegia venusta (Ker Gawl) Miers. (Bignoniaceae), has been traditionally used as a remedy for treating white patches and infections on the skin (leukoderma, vitiligo). To investigate wound healing and antimicrobial activity of flower extract of Pyrostegia venusta, including in vivo antioxidant activity. Methanolic extracts of Pyrostegia venusta flowers were studied for wound healing efficiency along with its effect on pro-inflammatory and anti-inflammatory cytokines was assessed using excision and incision model of wound repair in Wistar rats. Healing was assessed by the rate of wound contraction, tensile strength, breaking strength, hydroxyproline and hexosamine content. Antimicrobial activity of the flower extract against twelve microorganisms was also assessed. In vivo antioxidant activity was performed to understand the mechanism of wound healing potency. The results indicated that Pyrostegia venusta extract has potent wound healing capacity as evident from the wound contraction and increased tensile strength. Hydroxyproline and hexosamine expression were also correlative with the healing pattern observed. Pyrostegia venusta extract exhibited moderate antimicrobial activity against the organisms: Bacillus subtilis, Staphylococcus epidermidis, Staphylococcus pyogenes, Staphylococcus aureus, Escherichia coli, Micrococcus luteus, Enterobacter aerogenes, Salmonella typhi, Pseudomonas aeruginosa, Candida albicans, Aspergillus niger and Candida tropicana. During early wound healing phase TNF-α and IL-6 level were found to be up regulated by Pyrostegia venusta treatment. Increased wound contraction and tensile strength, augmented hydroxyproline and hexosamine content along with antioxidative activity and moderate antimicrobial activity support the early wound healing exhibited by Pyrostegia venusta flower extract. Induction in cytokine production may be one of the mechanisms involved in accelerating the wound healing by Pyrostegia venusta extract. Results suggest

jsc2017e136098 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 crewmembers Norishige Kanai of the Japan Aerospace Agency (JAXA, left), Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos, center) and Scott Tin

NASA Image and Video Library

2017-12-04

jsc2017e136098 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 crewmembers Norishige Kanai of the Japan Aerospace Agency (JAXA, left), Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos, center) and Scott Tingle of NASA (right) pose for pictures in front of a statue of Vladimir Lenin Dec. 4 prior to their departure for their launch site at the Baikonur Cosmodrome in Kazakhstan. They are scheduled to launch Dec. 17 on the Soyuz MS-07 spacecraft for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

An investigation of konjac glucomannan-keratin hydrogel scaffold loaded with Avena sativa extracts for diabetic wound healing.

PubMed

Veerasubramanian, Praveen Krishna; Thangavel, Ponrasu; Kannan, Ramya; Chakraborty, Sudip; Ramachandran, Balaji; Suguna, Lonchin; Muthuvijayan, Vignesh

2018-05-01

We have developed a novel hydrogel composed of konjac glucomannan (KGM), human hair proteins (KER), and an ethanolic extract of Avena sativa (OAT) and evaluated its potential as a dressing material for diabetic wounds. KGM is an excellent biocompatible gelling agent that stimulates fibroblast proliferation and immunomodulation. Human hair proteins (KER) are biocompatible, biodegradable, and possess abundant cell adhesion sites. KER also promotes fibroblast attachment and proliferation, keratinocyte migration, and collagen expression, which can accelerate wound healing. OAT consists of oat β-glucans and several anti-inflammatory and antioxidant moieties that can reduce prolonged inflammation in chronic wounds. SEM images confirm the highly porous architecture of the scaffolds. When immersed in PBS, KGM+KER+OAT hydrogels absorb 7.5 times their dry weight. These hydrogels display a measured rate of degradation in lysozyme. KGM+KER+OAT hydrogels showed no significant cytotoxicity against NIH/3T3 fibroblasts. DAPI and SEM images obtained after 48h of cell culture illustrate the attachment and infiltration of fibroblasts. In vivo studies performed using a diabetic rat excision wound model showed that KGM+KER+OAT hydrogels significantly accelerated wound healing compared to the control and the KGM+KER hydrogels. Copyright © 2018 Elsevier B.V. All rights reserved.

jsc2017e137344 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmember Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) tries his hand at a game of billiards Dec. 11 during a break in pre-launch tr

NASA Image and Video Library

2017-12-11

jsc2017e137344 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmember Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) tries his hand at a game of billiards Dec. 11 during a break in pre-launch training. Shkaplerov, Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) will launch Dec. 17 on the Soyuz MS-07 spacecraft from the Baikonur Cosmodrome for a five month mission on the International Space Station...Andrey Shelepin / Gagarin Cosmonaut Training Center.

jsc2017e136058 - On a snowy night at Red Square in Moscow, Expedition 54-55 crewmember Scott Tingle of NASA lays flowers at the Kremlin Wall where Russian space icons are interred in traditional pre-launch ceremonies Nov. 30. Tingle, Anton Shkaplerov of t

NASA Image and Video Library

2017-11-30

jsc2017e136058 - On a snowy night at Red Square in Moscow, Expedition 54-55 crewmember Scott Tingle of NASA lays flowers at the Kremlin Wall where Russian space icons are interred in traditional pre-launch ceremonies Nov. 30. Tingle, Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) will launch from the Baikonur Cosmodrome in Kazakhstan on the Soyuz MS-07 spacecraft Dec. 17 for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

One-Pot Synthesis of Biocompatible Silver Nanoparticle Composites from Cellulose and Keratin: Characterization and Antimicrobial Activity.

PubMed

Tran, Chieu D; Prosenc, Franja; Franko, Mladen; Benzi, Gerald

2016-12-21

A novel, simple method was developed to synthesize biocompatible composites containing 50% cellulose (CEL) and 50% keratin (KER) and silver in the form of either ionic (Ag + ) or Ag 0 nanoparticles (Ag + NPs or Ag 0 NPs). In this method, butylmethylimmidazolium chloride ([BMIm + Cl - ]), a simple ionic liquid, was used as the sole solvent and silver chloride was added to the [BMIm + Cl - ] solution of [CEL+KER] during the dissolution process. The silver in the composites can be maintained as ionic silver (Ag + ) or completely converted to metallic silver (Ag 0 ) by reducing it with NaBH 4 . The results of spectroscopy [Fourier transform infrared and X-ray diffraction (XRD)] and imaging [scanning electron microscopy (SEM)] measurements confirm that CEL and KER remain chemically intact and homogeneously distributed in the composites. Powder XRD and SEM results show that the silver in the [CEL+KER+Ag + ] and [CEL+KER+Ag 0 ] composites is homogeneously distributed throughout the composites in either Ag + (in the form of AgClNPs) or Ag 0 NPs form with sizes of 27 ± 2 or 9 ± 1 nm, respectively. Both composites were found to exhibit excellent antibacterial activity against many bacteria including Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, methicillin-resistant S. aureus (MRSA), and vancomycin-resistant Enterococus faecalis (VRE). The antibacterial activity of both composites increases with the Ag + or Ag 0 content in the composites. More importantly, for the same bacteria and the same silver content, the [CEL+KER+AgClNPs] composite is relatively more toxic than [CEL+KER+Ag 0 NPs] composite. Experimental results confirm that there was hardly any Ag 0 NPs release from the [CEL+KER+Ag 0 NPs] composite, and hence its antimicrobial activity and biocompatibility is due not to any released Ag 0 NPs but rather entirely to the Ag 0 NPs embedded in the composite. Both AgClNPs and Ag 0 NPs were found to be toxic to human fibroblasts at higher concentration

jsc2017e136056 - On a snowy night at Red Square in Moscow, Expedition 54-55 crewmembers Scott Tingle of NASA (left), Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos, center) and Norishige Kanai of the Japan Aerospace Exploration Agency (JA

NASA Image and Video Library

2017-11-30

jsc2017e136056 - On a snowy night at Red Square in Moscow, Expedition 54-55 crewmembers Scott Tingle of NASA (left), Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos, center) and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA, right) pose for pictures at the Kremlin Wall where Russian space icons are interred in traditional pre-launch ceremonies Nov. 30. They will launch from the Baikonur Cosmodrome in Kazakhstan on the Soyuz MS-07 spacecraft Dec. 17 for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

Cellulose, Chitosan and Keratin Composite Materials: Facile and Recyclable Synthesis, Conformation and Properties.

PubMed

Tran, Chieu D; Mututuvari, Tamutsiwa M

2016-03-07

A method was developed in which cellulose (CEL) and/or chitosan (CS) were added to keratin (KER) to enable [CEL/CS+KER] composites formed to have better mechanical strength and wider utilization. Butylmethylimmidazolium chloride ([BMIm + Cl - ]), an ionic liquid, was used as the sole solvent, and because the majority of [BMIm + Cl - ] used (at least 88%) was recovered, the method is green and recyclable. FTIR, XRD, 13 C CP-MAS NMR and SEM results confirm that KER, CS and CEL remain chemically intact and distributed homogeneously in the composites. We successfully demonstrate that the widely used method based on the deconvolution of the FTIR bands of amide bonds to determine secondary structure of proteins is relatively subjective as the conformation obtained is strongly dependent on the choice of parameters selected for curve fitting. A new method, based on the partial least squares regression analysis (PLSR) of the amide bands, was developed, and proven to be objective and can provide more accurate information. Results obtained with this method agree well with those by XRD, namely they indicate that although KER retains its second structure when incorporated into the [CEL+CS] composites, it has relatively lower α -helix, higher β -turn and random form compared to that of the KER in native wool. It seems that during dissolution by [BMIm + Cl - ], the inter- and intramolecular forces in KER were broken thereby destroying its secondary structure. During regeneration, these interactions were reestablished to reform partially the secondary structure. However, in the presence of either CEL or CS, the chains seem to prefer the extended form thereby hindering reformation of the α -helix. Consequently, the KER in these matrices may adopt structures with lower content of α -helix and higher β -sheet. As anticipated, results of tensile strength and TGA confirm that adding CEL or CS into KER substantially increase the mechanical strength and thermal stability of the [CS/CEL+KER

Corneal topography with an aberrometry-topography system.

PubMed

Mülhaupt, Michael; Dietzko, Sven; Wolffsohn, James; Bandlitz, Stefan

2018-05-07

To investigate the agreement between the central corneal radii and corneal eccentricity measurements generated by the new Wave Analyzer 700 Medica (WAV) compared to the Keratograph 4 (KER) and to test the repeatability of the instruments. 20 subjects (10 male, mean age 29.1 years, range 21-50 years) were recruited from the students and staff of the Cologne School of Optometry. Central corneal radii for the flat (r c/fl ) and steep (r c/st ) meridian as well as corneal eccentricity for the nasal (e nas ), temporal (e temp ), inferior (e inf ) and superior (e sup ) directions were measured using WAV and KER by one examiner in a randomized order. Central radii of the flat (r c/fl ) and steep (r c/st ) meridian measured with both instruments were statically significantly correlated (r = 0.945 and r = 0.951; p < 0.001). Comparison between the WAV and KER showed that r c/fl and r c/st measured with WAV were significantly steeper than those measured with KER (p < 0.001). Corneal eccentricities were statistically significantly correlated in all meridians (p < 0.05). Compared to KER, e temp and e sup measured with WAV were greater (p < 0.05), while there were no statistically significant differences for e nas and e inf (p = 0.350 and p = 0.083). For the central radii, repeated measurements were not significantly different for the KER or WAV (p > 0.05). Limits of agreement (LoA) indicate a better repeatability for the KER compared to WAV. Corneal topography measurements captured with the WAV were strongly correlated with the KER. However, due to the differences in measured corneal radii and eccentricities, the devices cannot be used interchangeably. For corneal topography the KER demonstrated better repeatability. Copyright © 2018 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

jsc2017e136097 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 crewmember Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) waves to well-wishers Dec. 4 as he boards a bus to depart for nearby Chkalovsky Ai

NASA Image and Video Library

2017-12-04

jsc2017e136097 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 crewmember Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) waves to well-wishers Dec. 4 as he boards a bus to depart for nearby Chkalovsky Airfield and a flight to his launch site at the Baikonur Cosmodrome in Kazakhstan. Shkaplerov, Norishige Kanai of the Japan Aerospace Agency (JAXA) and Scott Tingle of NASA will launch Dec. 17 on the Soyuz MS-07 spacecraft for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

Cysteic Acid in Dietary Keratin is Metabolized to Glutathione and Liver Taurine in a Rat Model of Human Digestion

PubMed Central

Wolber, Frances M.; McGrath, Michelle; Jackson, Felicity; Wylie, Kim; Broomfield, Anne

2016-01-01

Poultry feathers, consisting largely of keratin, are a low-value product of the poultry industry. The safety and digestibility of a dietary protein produced from keratin (KER) was compared to a cysteine-supplemented casein-based diet in a growing rat model for four weeks. KER proved to be an effective substitute for casein at 50% of the total dietary protein, with no changes in the rats’ food intake, weight gain, organ weight, bone mineral density, white blood cell counts, liver glutathione, or blood glutathione. Inclusion of KER in the diet reduced total protein digestibility from 94% to 86% but significantly increased total dietary cysteine uptake and subsequent liver taurine levels. The KER diet also significantly increased caecum weight and significantly decreased fat digestibility, resulting in a lower proportion of body fat, and induced a significant increase in blood haemoglobin. KER is therefore a safe and suitable protein substitute for casein, and the cysteic acid in keratin is metabolised to maintain normal liver and blood glutathione levels. PMID:26907334

Synthesis, structure and antimicrobial property of green composites from cellulose, wool, hair and chicken feather.

PubMed

Tran, Chieu D; Prosenc, Franja; Franko, Mladen; Benzi, Gerald

2016-10-20

Novel composites between cellulose (CEL) and keratin (KER) from three different sources (wool, hair and chicken feather) were successfully synthesized in a simple one-step process in which butylmethylimidazolium chloride (BMIm(+)Cl(-)), an ionic liquid, was used as the sole solvent. The method is green and recyclable because [BMIm(+)Cl(-)] used was recovered for reuse. Spectroscopy (FTIR, XRD) and imaging (SEM) results confirm that CEL and KER remain chemically intact and homogeneously distributed in the composites. KER retains some of its secondary structure in the composites. Interestingly, the minor differences in the structure of KER in wool, hair and feather produced pronounced differences in the conformation of their corresponding composites with wool has the highest α-helix content and feather has the lowest content. These results correlate well with mechanical and antimicrobial properties of the composites. Specifically, adding CEL into KER substantially improves mechanical strength of [CEL+KER] composites made from all three different sources, wool, hair and chicken feathers i.e., [CEL+wool], [CEL+hair] and [CEL+feather]. Since mechanical strength is due to CEL, and CEL has only random structure, [CEL+feather] has, expectedly, the strongest mechanical property because feather has the lowest content of α-helix. Conversely, [CEL+wool] composite has the weakest mechanical strength because wool has the highest α-helix content. All three composites exhibit antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA). The antibacterial property is due not to CEL but to the protein and strongly depends on the type of the keratin, namely, the bactericidal effect is strongest for feather and weakest for wool. These results together with our previous finding that [CEL+KER] composites can control release of drug such as ciprofloxacin clearly indicate that these composites can potentially be used as wound dressing. Copyright © 2016 Elsevier

Synthesis, Structure and Antimicrobial Property of Green Composites from Cellulose, Wool, Hair and Chicken Feather

PubMed Central

Tran, Chieu D.; Prosenc, Franja; Franko, Mladen; Benzi, Gerald

2016-01-01

Novel composites between cellulose (CEL) and keratin (KER) from three different sources (wool, hair and chicken feather) were successfully synthesized in a simple one-step process in which butylmethylimidazolium chloride (BMIm+Cl−), an ionic liquid, was used as the sole solvent. The method is green and recyclable because [BMIm+Cl−] used was recovered for reuse. Spectroscopy (FTIR, XRD) and imaging (SEM) results confirm that CEL and KER remain chemically intact and homogeneously distributed in the composites. KER retains some of its secondary structure in the composites. Interestingly, the minor differences in the structure of KER in wool, hair and feather produced pronounced differences in the conformation of their corresponding composites with wool has the highest α-helix content and feather has the lowest content. These results correlate well with mechanical and antimicrobial properties of the composites. Specifically, adding CEL into KER substantially improves mechanical strength of [CEL+KER] composites made from all three different sources, wool, hair and chicken feathers (i.e., [CEL+wool], [CEL+hair] and [CEL+feather]. Since mechanical strength is due to CEL, and CEL has only random structure, [CEL+feather] has, expectedly, the strongest mechanical property because feather has the lowest content of α-helix. Conversely, [CEL+wool] composite has the weakest mechanical strength because wool has the highest α-helix content. All three composites exhibit antibacterial activity against methicillin resistant S. aureus (MRSA). The antibacterial property is due not to CEL but to the protein and strongly depends on the type of the keratin, namely, the bactericidal effect is strongest for feather and weakest for wool. These results together with our previous finding that [CEL+KER] composites can control release of drug such as ciprofloxacin clearly indicate that these composites can potentially be used as wound dressing PMID:27474680

Regional Seismograms: Attenuation and Scattering

DTIC Science & Technology

1992-03-06

Ningya Cheng Anton M. Dainty Batakrishna Mandal Chengbin Peng Craig A. Schultz Earth Rc3ources Laboratory Department of Earth, Atmospheric, and Planetary...Institute of Technology Anton M. Dainty, Founding Member Fellow, Massachusetts Institute of Technology Batakrishna Mandal, Research Scientist, Massachusetts...particular I would like to thank Chris "dude" Bradley, Richard Coates, Vern Cormier, Anton Dainty, Joe Matarese, Jeff Meredith, Mike Prange, Bill

jsc2017e136047 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 prime crewmember Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) signs a ceremonial book Nov. 30 as part of traditional pre-launch ceremonies

NASA Image and Video Library

2017-11-30

jsc2017e136047 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 prime crewmember Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) signs a ceremonial book Nov. 30 as part of traditional pre-launch ceremonies. In the front row from left to right are the prime crewmembers, Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA), Shkaplerov and Scott Tingle of NASA. Looking on in the back row are the backup crewmembers, NASA’s Jeanette Epps, Sergey Prokopyev of Roscosmos and Alexander Gerst of the European Space Agency. Shkaplerov, Tingle and Kanai will launch Dec. 17 on the Soyuz MS-07 spacecraft from the Baikonur Cosmodrome in Kazakhstan for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

Use of OSL dating to establish the stratigraphic framework of Quaternary eolian sediments, Anton scarp upper trench, Northeastern Colorado High Plains, USA

USGS Publications Warehouse

Mahan, S.A.; Noe, D.C.; McCalpin, J.P.

2009-01-01

This paper contains the results of the optically stimulated luminescence (OSL) dating used to establish stratigraphic ages and relationships of eolian sediments in a trench in northeastern Colorado, USA. This trench was located in the upper face of the Anton scarp, a major topographic lineament trending NW-SE for a distance of 135 km, in anticipation of intersecting near-surface faulting. The trench was 180 m long, 4.5-6.0 m deep, and exposed 22 m of stratigraphic section, most of which dipped gently west and was truncated by gulley channeling at the face of the scarp. No direct evidence of faulting was found in the upper trench. The stratigraphy from the trench was described, mapped and dated using OSL on quartz and potassium feldspar, and 14C obtained from woody material. OSL dating identified two upper loess units as Peoria Loess and Gilman Canyon Loess, deposited between 16 and 30 ka ago. The bottom layers of the trench were substantially older, giving OSL ages in excess of 100 ka. These older ages are interpreted as underestimates, owing to saturation of the fast component of OSL. Using OSL and 14C dating, we can constrain the erosion and down cutting of the scarp face as occurring between 16 and 5.7 ka. As the trenching investigation continues in other parts of the scarp face, the results of this preliminary study will be of importance in relating the ages of the strata that underlie different parts of the scarp, and in determining whether Quaternary faulting was a mechanism that contributed to the formation of this regional geomorphic feature.

Observation of fast and slow interatomic Coulombic decay in argon dimers induced by electron-impact ionization

NASA Astrophysics Data System (ADS)

Ren, Xueguang; Miteva, Tsveta; Kolorenč, Přemysl; Gokhberg, Kirill; Kuleff, Alexander I.; Cederbaum, Lorenz S.; Dorn, Alexander

2017-09-01

We investigate the interatomic Coulombic decay (ICD) in argon dimers induced by electron-impact ionization (E0=90 eV ) using a multiparticle coincidence experiment in which the momentum vectors and, consequently, the kinetic energies for electrons and fragment ions are determined. The signature of the ICD process is obtained from a correlation map between ejected electron energy and kinetic energy release (KER) for Ar++Ar+ fragment ions where low-energy ICD electrons can be identified. Furthermore, two types of ICD processes, termed fast and slow interatomic decay, are separated by the ICD initial-state energies and projectile energy losses. The dependence of the energies of emitted low-energy ICD electrons on the initial-state energy is studied. ICD electron energy spectra and KER spectra are obtained separately for fast and slow decay processes where the KER spectra for the slow decay channel are strongly influenced by nuclear motion. The KER and ICD electron energy spectra are well reproduced by ab initio calculations.

[The tribute of the pioneer of hypnotherapy--Franz Anton Mesmer, MD, PhD in the history of psychotherapy and medicine].

PubMed

Radovancević, Ljubomir

2009-01-01

Modern hypnosis started with the Austrian physician Franz Anton Mesmer (1734-1815), who believed that the phenomenon known as mesmerism, or animal magnetism, or fluidum was related to an invisible substance--a fluid that runs within the subject or between the subject and the therapist, that is, the hypnotist, or the "magnetizer". The term hypnosis was introduced in the 1840s by a Scottish surgeon James Braid (1795-1860), who believed the subject to be in a particular state of sleep--a trance. In the late 19th century, a French neurologist Jean Martin Charcot (1825-1893) thought hypnotism to be a special physiological state, and his contemporary Hyppotite-Marie Bernheim (1840-1919) believed it to be a psychological state of heightened suggestibility. Sigmund Freud, who studied with Charcot, used hypnosis early in his career to help patients recover repressed memories. He noted that patients would relive traumatic events while under hypnosis, a process know as abreaction. Freud later replaced hypnosis with the technique of free associations. Today, hypnosis is used as a form of therapy (hypnotherapy), a method of investigation to recover lost memories, and research tool. According to Caplan & Sadock, F.A. Mesmer is generally thought of as the fons et origo of modern psychotherapy; and from the early techniques of mesmerism, it is said, have evolved the more elaborate and sophisticated therapeutic measures of the analyst and his colleagues. Although Mesmer was certainly dealing with individuals suffering from a variety of neurotic disorders, and though the clinical successes he achieved were the result of psychological processes that his procedures induced in his patients, Mesmer's theoretical formulations, his understanding of the nature of the treatment he developed, and his specific procedures were all totally different from those of the 20th century analyst. He was one of the corne stones in the development of psychoanalysis through hypnosis mainly of hysterical

Roseomonas aeriglobus sp. nov., isolated from an air-conditioning system.

PubMed

Lee, Yunho; Jeon, Che Ok

2018-03-01

A novel pale pink-coloured, strictly aerobic, Gram-stain negative bacterial strain, designated strain KER25-12 T , was isolated from a laboratory air-conditioning system in South Korea. Cells were observed to be non-motile cocci showing positive catalase and oxidase reactions. Strain KER25-12 T was found to grow at 10-30 °C (optimum, 25-30 °C), at pH 4.0-9.0 (optimum, pH 6.0-7.0) and in the presence of 0-2% (w/v) NaCl (optimum, 0%). Ubiquinone-10 and spermidine were detected as the sole respiratory quinone and the predominant polyamine, respectively. The major fatty acids were identified as summed feature 8 (comprising C 18:1 ω7c and/or C 18:1 ω6c), summed feature 3 (comprising C 16:1 ω7c and/or C 16:1 ω6c), C 16:0 and C 18:0 . The genomic DNA G+C content of strain KER25-12 T was determined to be 70.0 mol%. The major polar lipids were identified as diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, phosphatidylcholine and an unidentified aminolipid. Phylogenetic analysis based on 16S rRNA gene sequence comparison revealed that strain KER25-12 T belongs to the genus Roseomonas and shows high sequence similarity to Roseomonas aerilata 5420S-30 T (98.57%), Roseomonas pecuniae N75 T (97.44%) and Roseomonas vinacea CPCC 100056 T (97.40%). Based on the morphological, physiological, chemotaxonomic and phylogenetic features, strain KER25-12 T is concluded to represent a novel species of the genus Roseomonas, for which the name Roseomonas aeriglobus sp. nov. is proposed. The type strain is KER25-12 T (= KACC 19282 T  = JCM 32049 T ).

Influence of Kuroshio Oceanic Eddies on North Pacific Weather Patterns

NASA Astrophysics Data System (ADS)

Ma, X.; Chang, P.; Saravanan, R.; Montuoro, R.; Hsieh, J. S.; Wu, D.; Lin, X.; Wu, L.; Jing, Z.

2016-02-01

High-resolution satellite observations reveal energetic meso-scale ocean eddy activity and positive correlation between meso-scale sea surface temperature (SST) and surface wind along oceanic frontal zones, such as the Kuroshio and Gulf Stream, suggesting a potential role of meso-scale oceanic eddies in forcing the atmosphere. Using a 27 km horizontal resolution Weather Research Forecasting (WRF) model forced with observed daily SST at 0.09° spatial resolution during boreal winter season, two ensembles of 10 WRF simulations, in one of which meso-scale SST variability induced by ocean eddies was suppressed, were conducted in the North Pacific to study the local and remote influence of meso-scale oceanic eddies in the Kuroshio Extention Region (KER) on the atmosphere. Suppression of meso-scale oceanic eddies results in a deep tropospheric response along and downstream of the KER, including a significant decrease (increase) in winter season mean rainfall along the KER (west coast of US), a reduction of storm genesis in the KER, and a southward shift of the jet stream and North Pacific storm track in the eastern North Pacific. The simulated local and remote rainfall response to meso-scale oceanic eddies in the KER is also supported by observational analysis. A mechanism invoking moist baroclinic instability is proposed as a plausible explanation for the linkage between meso-scale oceanic eddies in the KER and large-scale atmospheric response in the North Pacific. It is argued that meso-scale oceanic eddies can have a rectified effect on planetary boundary layer moisture, the stability of the lower atmosphere and latent heat release, which in turn affect cyclogenesis. The accumulated effect of the altered storm development downstream further contributes to the equivalent barotropic mean flow change in the eastern North Pacific basin.

Electron Localization in Molecular Fragmentation of H{sub 2} by Carrier-Envelope Phase Stabilized Laser Pulses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kremer, Manuel; Fischer, Bettina; Feuerstein, Bernold

2009-11-20

Fully differential data for H{sub 2} dissociation in ultrashort (6 fs, 760 nm), linearly polarized, intense (0.44 PW/cm{sup 2}) laser pulses with a stabilized carrier-envelope phase (CEP) were recorded with a reaction microscope. Depending on the CEP, the molecular orientation, and the kinetic energy release (KER), we find asymmetric proton emission at low KERs (0-3 eV), basically predicted by Roudnev and Esry, and much stronger than reported by Kling et al. Wave packet propagation calculations reproduce the salient features and discard, together with the observed KER-independent electron asymmetry, the first ionization step to be the reason for the asymmetric protonmore » emission.« less

Anton permselective membrane

NASA Technical Reports Server (NTRS)

Alexander, S. S.; Hodgdon, R. B.; Waite, W. A.

1979-01-01

Experimental composite membranes were synthesized on a lab scale consisting of a thin layer of anion permselective resin supported by and bonded to a porous physically strong and conductive substrate film. These showed good selectivity and also substantially lower electrical resistivities than the homogenous candidate membranes optimized in the previous contract. A wide range of resin porosities were examined for three candidate membrane systems, CDIL, CP4L, and A3L to identify the formulation giving the best overall redox cell performance. Candidate anion membranes showed large increases in resistivity after a short time of immersion in concentrated FeCl/HCl solution. Largely on the basis of resistance stability the CDIL formulation was selected as prime candidate and about thirty-five membranes (one foot square) were produced for experimental static and dynamic evaluation.

Inference for Distributions over the Permutation Group

DTIC Science & Technology

2008-05-01

world problems, such as voting , ranking, and data association. Representing uncertainty over permutations is challenging, since there are n...problems, such as voting , ranking, and data association. Representing uncertainty over permutations is challenging, since there are n! possibilities...the Krone ker (or Tensor ) Produ t Representation.In general, the Krone ker produ t representation is redu ible, and so it ande omposed into a dire t

Carbon Nanotube Based Flexible Supercapacitors

DTIC Science & Technology

2011-04-01

Carbon Nanotube Based Flexible Supercapacitors by Christopher M. Anton and Matthew H. Ervin ARL-TR-5522 April 2011...Carbon Nanotube Based Flexible Supercapacitors Christopher M. Anton and Matthew H. Ervin Sensors and Electron Devices Directorate, ARL...September 2010 4. TITLE AND SUBTITLE Carbon Nanotube Based Flexible Supercapacitors 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

Structures in color space

NASA Astrophysics Data System (ADS)

Petrov, Alexander P.

1996-09-01

Classic colorimetry and the traditionally used color space do not represent all perceived colors (for example, browns look dark yellow in colorimetric conditions of observation) so, the specific goal of this work is to suggest another concept of color and to prove that the corresponding set of colors is complete. The idea of our approach attributing color to surface patches (not to the light) immediately ties all the problems of color perception and vision geometry. The equivalence relation in the linear space of light fluxes F established by a procedure of colorimetry gives us a 3D color space H. By definition we introduce a sample (sigma) (surface patch) as a linear mapping (sigma) : L yields H, where L is a subspace of F called the illumination space. A Dedekind structure of partial order can be defined in the set of the samples: two samples (alpha) and (Beta) belong to one chromatic class if ker(alpha) equals ker(Beta) and (alpha) > (Beta) if ker(alpha) ker(Beta) . The maximal elements of this chain create the chromatic class BLACK. There can be given geometrical arguments for L to be 3D and it can be proved that in this case the minimal element of the above Dedekind structure is unique and the corresponding chromatic class is called WHITE containing the samples (omega) such that ker(omega) equals {0} L. Color is defined as mapping C: H yields H and assuming color constancy the complete set of perceived colors is proved to be isomorphic to a subset C of 3 X 3 matrices. This subset is convex, limited and symmetrical with E/2 as the center of symmetry. The problem of metrization of the color space C is discussed and a color metric related to shape, i.e., to vision geometry, is suggested.

Sphingomonas frigidaeris sp. nov., isolated from an air conditioning system.

PubMed

Lee, Yunho; Jeon, Che Ok

2017-10-01

A strictly aerobic Gram-stain-negative bacterium, designated strain KER25-10 T , was isolated from a laboratory air conditioning system in South Korea. Cells were yellow-pigmented, non-motile rods showing catalase- and oxidase-positive reactions. The strain grew at pH 4.0-9.0 (optimum, pH 6.0-7.0) and 10-40 °C (optimum, 30 °C) and in the presence of 0-3 % (w/v) NaCl (optimum, 0 %). The G+C content of the genomic DNA was 65.1 mol%. Strain KER25-10 T contained ubiquinone-10 (Q-10) as the predominant isoprenoid quinone and C16 : 0, C17 : 1ω6c, summed feature 3 (comprising C16 : 1ω7c and/or C16 : 1ω6c) and summed feature 8 (comprising C18 : 1ω7c and/or C18 : 1ω6c) as the major fatty acids. The major polar lipids were sphingoglycolipid, diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine and phosphatidylcholine. Only spermidine was detected as the polyamine. Phylogenetic analysis based on 16S rRNA sequences indicated that strain KER25-10 T formed a distinct phylogenetic lineage within the genus Sphingomonas of the family Sphingomonadaceae and the strain was most closely related to Sphingomonas kyeonggiense THG-DT81 T with a 96.8 % 16S rRNA gene sequence similarity. On the basis of phenotypic, chemotaxonomic and molecular features, strain KER25-10 T clearly represents a novel species of the genus Sphingomonas, for which the name Sphingomonas frigidaeris sp. nov. is proposed. The type strain is KER25-10 T (=KACC 19285 T =JCM 32053 T ).

Dynamics of C2H 2 3 +→H++H++C 2 + investigated by 50-keV/u Ne8 + impact

NASA Astrophysics Data System (ADS)

Xu, S.; Zhu, X. L.; Feng, W. T.; Guo, D. L.; Zhao, Q.; Yan, S.; Zhang, P.; Zhao, D. M.; Gao, Y.; Zhang, S. F.; Yang, J.; Ma, X.

2018-06-01

Breakup dynamics of C2H 2 3 + → H++H++C 2 + induced by 50-keV/u Ne8 + ion impact is investigated employing a reaction microscope. All three ionic fragments in the final state are detected in coincidence, and their momentum vectors as well as the kinetic energies are determined. The kinetic-energy correlation spectrum of the two protons displays very rich structures. Utilizing the Newton diagrams and the Dalitz plots, different dissociation mechanisms corresponding to these structures are identified. It was found that, besides the concerted and sequential breakup, fragmentation mechanisms associated with different vibration modes including molecular bending and asymmetric stretching also make significant contributions. We analyzed the correlation between different fragmentation mechanisms and the kinetic-energy release (KER) and found that the sequential process occurs with higher KER while, in contrast, the concerted process mainly contributes to the lower KER. This behavior is entirely opposite to the breakup of the CO2 molecule.

Investigating the Acquisition of Software Systems that Rely on Open Architecture and Open Source Software

DTIC Science & Technology

2010-03-01

associated with certain software systems [Breaux and Anton 2008]. With this basis to build on, it is now possible to analyze the alignment of...Kazman, R., (2003). Software Architecture in Practice, 2nd Edition, Addison-Wesley Pro- fessional, New York.. Breaux, T.D. and Anton , A.I. (2008... calculus for license rights and obligations in license and context models. Using them, we calculate rights and obligations for specific sys- tems, identify

Reprisal Under International Law: A Defense to Criminal Conduct?

DTIC Science & Technology

2009-03-25

that authority in denying a reprisal defense. In the trial of General Anton Dostler in October 1945, the Commission reaffirmed there could be no...experience. This causal proximity may be part of the calculus that supports a soldier’s 15 decision to reprise, and the soldier must know his decision...and Accountability Under International Law, 131. 26 Ibid., 133. 27 Trial of General Anton Dostler, United States Military Commission, Rome, 8-12

Further Results on the Disturbance Response of a Double Integrator Controlled by Saturating Linear Static State Feedback

DTIC Science & Technology

2011-07-13

Anton A. Stoorvogel b, Håvard Fjær Grip a aSchool of Electrical Engineering and Computer Science, Washington State University, Pullman, WA 99164-2752...utwente.nl ( Anton A. Stoorvogel), grip@ieee.org (Håvard Fjær Grip). of a double integrator controlled by a saturating linear static state feedback...References Chitour, Y., 2001. On the Lp stabilization of the double integrator subject to input saturation. ESAIM: Control, Optimization and Calculus

A Probe for Measuring Spacecraft Surface Potentials Using a Direct-Gate Field Effect Transistor.

DTIC Science & Technology

1983-09-30

SURFACE POTENTIALS USING A DIRECT-GATE FIELD EFFECT TRANSISTOR Mark N. Horenstein Anton Havretic Trustees of Boston University 881 Commonwealth Avenue...1933 Transistor 6. PERFORMING ORG. REPORT NUMBER 7. AUTHOR(s) S. CONTRACT OR GRANT NUMBER(&) ’_5 Mark N. Horenstein Anton Mavretic F19628-82-K-00 34...at AFGL. These tests can be considered the bench mark tests for device performance, with all elements of the monitoring system optimized to eliminate

The consequences of two distinct reaction coordinates in the decomposition of the ethylamine cation conformers

NASA Astrophysics Data System (ADS)

Petersen, Allan C.; Sølling, Theis I.

2018-06-01

The ethylamine cation CH3CH2NH2+ is shown to loose CH3 accompanied by a bimodal kinetic energy release. CH3CH2NH2+ exists in two conformeric forms, which are computationally shown to be distinct minima. The barrier separating the conformers is modest compared to the energy requirement for dissociation, and the conformers are so easily interconverted that the reactions take place from a mixture of the two conformers in equilibrium. However, once a reaction begins it is conformer-specific. The reaction from one conformational origin takes place by simple cleavage along a one-dimensional reaction coordinate, whereas reaction from the other origin is by a complex reaction mechanism with a two- or possibly three-dimensional reaction coordinate. Reaction by the former mechanism is a statistical process associated with a low kinetic energy release (KER), while the latter is non-statistical giving rise to a very low KER. The experimental result is a composite signal due to the superposition of two simple Gaussians, each corresponding to their respective KER.

The Future of Officer Career Development System in the Slovenian Armed Forces

DTIC Science & Technology

2013-12-13

Professors Anton Zabkar and Uros Svete, at the Faculty for Social Science at University of Ljubljana, clearly identified the deficiencies in the...short-lived solution], Slovenian Armed Forces Bulletin 10, no. 1 (May 2008): 97-120. 5Anton Zabkar and Uros Svete, “Solanje Vojaskih Profesionalcev...is based on Length of Service ( LoS ) and applies to all DE officers and the other is the LE career structure.87 85Major Al Thorp, e-mail message to

Ship-borne measurements of microbial enzymatic activity: A rapid biochemical indicator for microbial water quality monitoring

NASA Astrophysics Data System (ADS)

Stadler, Philipp; Loken, Luke; Crawford, John; Schramm, Paul; Sorsa, Kirsti; Kuhn, Catherine; Savio, Domenico; Striegl, Rob; Butman, David; Stanley, Emily; Farnleitner, Andreas H.; Zessner, Matthias

2017-04-01

Contamination of aquatic ecosystems by human and animal wastes is a global concern for water quality. Disclosing fate and transport processes of fecal indicator organism (FIO) in large water bodies is a big challenge due to material intensive and time consuming methods used in microbiological water quality monitoring. In respect of utilization of large surface water resources there is a dearth of rapid microbiological methods that allow a near-real time health related water quality monitoring to be implemented into early warning systems. The detection of enzymatic activities has been proposed as a rapid surrogate for microbiological pollution monitoring of water and water resources (Cabral, 2010; Farnleitner et al., 2001, 2002). Methods such as the beta-D-Glucuronidase assay (GLUC), targeting FIO such as E. coli, were established. New automated enzymatic assays have been implemented during the last years into on-site monitoring stations, ranging from ground- to surface waters (Ryzinska-Paier et al., 2014; Stadler et al., 2017, 2016). While these automated enzymatic methods cannot completely replace assays for culture-based FIO enumeration, they yielded significant information on pollution events and temporal dynamics on a catchment specific basis, but were restricted to stationary measurements. For the first time we conducted ship-borne and automated measurements of enzymatic GLUC activity on large fresh water bodies, including the Columbia River, the Mississippi River and Lake Mendota. Not only are automated enzymatic assays technically feasible from a mobile vessel, but also can be used to localize point sources of potential microbial fecal contamination, such as tributaries or storm drainages. Spatial and temporal patterns of enzymatic activity were disclosed and the habitat specific correlation with microbiological standard assays for FIO determined due to reference samples. The integration of rapid and automated enzymatic assays into well-established systems

Anatomical Features and Early Outcomes of Endovascular Repair of Abdominal Aortic Aneurysm from a Korean Multicenter Registry.

PubMed

Kwon, Hyunwook; Lee, Do Yun; Choi, Soo Jin Na; Park, Ki Hyuk; Min, Seung-Kee; Chang, Jeong-Hwan; Huh, Seung; Jeon, Yong Sun; Won, Jehwan; Byun, Seung Jae; Park, Sang Jun; Jang, Lee Chan; Kwon, Tae-Won

2015-09-01

To introduce a nation-based endovascular aneurysm repair (EVAR) registry in South Korea and to analyze the anatomical features and early clinical outcomes of abdominal aortic aneurysms (AAA) in patients who underwent EVAR. The Korean EVAR registry (KER) was a template-based online registry developed and established in 2009. The KER recruited 389 patients who underwent EVAR from 13 medical centers in South Korea from January 2010 to June 2010. We retrospectively reviewed the anatomic features and 30-day clinical outcomes. Initial deployment without open conversion was achieved in all cases and procedure-related 30-day mortality rate was 1.9%. Anatomic features showed the following variables: proximal aortic neck angle 48.8±25.7° (mean±standard deviation), vertical neck length 35.0±17.2 mm, aneurysmal sac diameter 57.2±14.2 mm, common iliac artery (CIA) involvement in 218 (56.3%) patients, and median right CIA length 34.9 mm. Two hundred and nineteen (56.3%) patients showed neck calcification, 98 patients (25.2%) had neck thrombus, and the inferior mesenteric arteries of 91 patients (23.4%) were occluded. Anatomical features of AAA in patients from the KER were characterized as having angulated proximal neck, tortuous iliac artery, and a higher rate of CIA involvement. Long-term follow-up and ongoing studies are required.

Equality judgments cannot distinguish between attention effects on appearance and criterion: a reply to Schneider (2011).

PubMed

Anton-Erxleben, Katharina; Abrams, Jared; Carrasco, Marisa

2011-01-01

Whether attention modulates the appearance of stimulus features is debated. Whereas many previous studies using a comparative judgment have found evidence for such an effect, two recent studies using an equality judgment have not. Critically, these studies have relied on the assumption that the equality paradigm yields bias-free PSE estimates and is as sensitive as the comparative judgment, without testing these assumptions. Anton-Erxleben, Abrams, and Carrasco (2010) compared comparative judgments and equality judgments with and without the manipulation of attention. They demonstrated that the equality paradigm is less sensitive than the comparative judgment and also bias-prone. Furthermore, they reported an effect of attention on the PSE using both paradigms. Schneider (2011) questions the validity of the latter finding, stating that the data in the equality experiment are corrupted because of skew in the response distributions. Notably, this argument supports the original conclusion by Anton-Erxleben et al.: that the equality paradigm is bias-prone. Additionally, the necessary analyses to show that the attention effect observed in Anton-Erxleben et al. was due to skew in the data were not conducted. Here, we provide these analyses and show that although the equality judgment is bias-prone, the effects we observe are consistent with an increase of apparent contrast by attention.

Equality judgments cannot distinguish between attention effects on appearance and criterion: A reply to Schneider (2011)

PubMed Central

Anton-Erxleben, Katharina; Abrams, Jared; Carrasco, Marisa

2012-01-01

Whether attention modulates the appearance of stimulus features is debated. Whereas many previous studies using a comparative judgment have found evidence for such an effect, two recent studies using an equality judgment have not. Critically, these studies have relied on the assumption that the equality paradigm yields bias-free PSE estimates and is as sensitive as the comparative judgment, without testing these assumptions. Anton-Erxleben, Abrams, and Carrasco (2010) compared comparative judgments and equality judgments with and without the manipulation of attention. They demonstrated that the equality paradigm is less sensitive than the comparative judgment and also bias-prone. Furthermore, they reported an effect of attention on the PSE using both paradigms. Schneider (2011) questions the validity of the latter finding, stating that the data in the equality experiment are corrupted because of skew in the response distributions. Notably, this argument supports the original conclusion by Anton-Erxleben et al.: that the equality paradigm is bias-prone. Additionally, the necessary analyses to show that the attention effect observed in Anton-Erxleben et al. was due to skew in the data were not conducted. Here, we provide these analyses and show that although the equality judgment is bias-prone, the effects we observe are consistent with an increase of apparent contrast by attention. PMID:22072728

Adverse Outcome Pathway (AOP) for a Mutagenic Mode of ...

EPA Pesticide Factsheets

AOPs provide a framework to describe a sequence of measureable key events (KEs), beginning with a molecular initiating event (MIE), followed by a series of identified KEs linked to one another by KE Relationships (KERs), all anchored by a specific adverse outcome (AO). Each KE/KER is supported by data and evaluated against criteria to assess biological plausibility, weight/strength of evidence, specificity, and confidence. AOPs offer an approach to using toxicological data and predictive modeling to actualize use of mode-of-action (MOA) for such purposes as read-across, integrated approaches to testing & assessment, and risk assessment. Different applications will depend partly on the scientific confidence underpinning each KE/KER and the overall AOP. An OECD program encourages development of AOPs, with a wiki that allows for public review & comment to foster collaborations and broaden understanding & application of AOPs. Developing an AOP for a mutagenic MOA for cancer as a case study in the OECD program lays a path towards determination of such an MOA and its use in chemical assessment programs. Aflatoxin B1 (AFB1), with ubiquitous exposure and a rich database, was selected for this case study. AFB1 has been determined to induce HCC via a DNA-reactive MOA in many species, including humans. The sequential KEs identified for AFB1 are as follows: pre-MIE: Hepatic metabolic activation; MIE: Formation of a pro-mutagenic DNA adduct (N7-AFB1-guanine or AFB1-FAPy); KE

Single-photon Coulomb explosion of methanol using broad bandwidth ultrafast EUV pulses.

PubMed

Luzon, Itamar; Jagtap, Krishna; Livshits, Ester; Lioubashevski, Oleg; Baer, Roi; Strasser, Daniel

2017-05-31

Single-photon Coulomb explosion of methanol is instigated using the broad bandwidth pulse achieved through high-order harmonics generation. Using 3D coincidence fragment imaging of one molecule at a time, the kinetic energy release (KER) and angular distributions of the products are measured in different Coulomb explosion (CE) channels. Two-body CE channels breaking either the C-O or the C-H bonds are described as well as a proton migration channel forming H 2 O + , which is shown to exhibit higher KER. The results are compared to intense-field Coulomb explosion measurements in the literature. The interpretation of broad bandwidth single-photon CE data is discussed and supported by ab initio calculations of the predominant C-O bond breaking CE channel. We discuss the importance of these findings for achieving time resolved imaging of ultrafast dynamics.

A New Species of Hymenocallis (Amaryllidaceae) in the Florida Panhandle

USGS Publications Warehouse

Smith, Gerald L.; Darst, Melanie R.

1994-01-01

A new species of spider-lily, Hymenocallis godfreyi, is described and illustrated. It is a rare endemic that occurs in the St. Marks and Wakulla Rivers, Florida. Its striking features are contrasted to an allied species Hymenocallis rotata (Ker-Gawler) Herbert.

78 FR 1210 - Notice of Membership of Performance Review Board for Senior Executives (PRB)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

...., Section 4314(c)(4). The Commission's PRB will remove the following member: Charles H. Schneider The Commission's PRB will add the following member: Anton C. Porter, PRB Chairman Dated: January 2, 2013...

Design and Implementation of a Relational Database Management System for the AFIT Thesis Process.

DTIC Science & Technology

1985-09-01

AIRLIFT Gourdin 4. APPLIED MATHEMATICS Daneman Lee Na rga rsen ker 5. ARTIFICIAL INTELLEGENCE Gen et 6. CAPARILITY ASSESSMENT S Budde Talbott 31...05 ARTIFICIAL INTELLIGENCE 06 CAPABILITY ASSESSMENT 07 COMMUNIICATIONS 08 COMPUTER AIDED DESIGN 09 COMPUTER BASED TRAINING 10 COMPUTER SOFTWARE 11

78 FR 10692 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-14

... ROBERT DANIEL HESS JOCELYN CAMPOS HIGHFIELD TUCKER M JONSSON N STEPHAN W LEUNG JANICE T L LEVY-LANG... SCHMITH SCOTT CHARLES SHOLSETH THOMAS JOSEPH SIGG ALFRED STEWART HOLLY DAWN STUDER ANTON ALOIS VAN...

Shkaplerov makes a selection from food container

NASA Image and Video Library

2012-02-03

ISS030-E-117514 (3 Feb. 2012) --- Russian cosmonaut Anton Shkaplerov, Expedition 30 flight engineer, makes a selection from a food storage container in the Zvezda Service Module of the International Space Station.

Shkaplerov exercises on the aRED

NASA Image and Video Library

2012-01-05

ISS030-E-235507 (5 Jan. 2012) --- Russian cosmonaut Anton Shkaplerov, Expedition 30 flight engineer, exercises using the advanced Resistive Exercise Device (aRED) in the Tranquility node of the International Space Station.

ISS Expedition 42 Crew Profiles - Version 01

NASA Image and Video Library

2014-11-14

Narrated program with biographical information about ISS Expedition 42 crewmembers Terry Virts, Samantha Cristoforetti and Anton Shjaplerov. The program covers the crewmember's career including childhood photographs; footage from previous missions; and interview sound bites.

ISS Expedition 54-55 Docking, Hatch Opening and Welcome Activities

NASA Image and Video Library

2017-12-19

After launching Dec. 17 in their Soyuz MS-07 spacecraft from the Baikonur Cosmodrome in Kazakhstan, Expedition 54-55 Soyuz Commander Anton Shkaplerov of Roscosmos and Flight Engineers Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) arrived at the International Space Station Dec. 19 to complete a two-day journey, docking their vehicle to the Rassvet module on the Russian segment of the complex. A few hours after docking their Soyuz MS-07 spacecraft to the International Space Station, Expedition 54-55 Soyuz Commander Anton Shkaplerov of Roscosmos and Flight Engineers Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA), opened hatches and were greeted by station Commander Alexander Misurkin of Roscosmos and Flight Engineers Joe Acaba and Mark Vande Hei of NASA.

Adverse Outcome Pathway (AOP) for a Mutagenic Mode of Action for Cancer: AFB1 and Hepatocellular Carcinoma (HCC)

EPA Science Inventory

AOPs provide a framework to describe a sequence of measureable key events (KEs), beginning with a molecular initiating event (MIE), followed by a series of identified KEs linked to one another by KE Relationships (KERs), all anchored by a specific adverse outcome (AO). Each KE/KE...

Discriminating Nonpareil marketing group almond cultivars through multivariate analyses

USDA-ARS?s Scientific Manuscript database

The California almond industry produces over 80% of the world’s almonds with nearly 2 billion pounds harvested in 2011. Several dozen cultivars are grown, but the Nonpareil cultivar is dominant in both acreage and tonnage. Almond cultivars are categorized into defined marketing groups based on ker...

Theoretical study of the photodissociation of Li(2)+ in one-color intense laser fields.

PubMed

Li, Yuanjun; Jiang, Wanyi; Khait, Yuriy G; Hoffmann, Mark R

2011-05-07

A theoretical treatment of the photodissociation of the molecular ion Li(2) (+) in one-color intense laser fields, using the time-dependent wave packet approach in a Floquet Born-Oppenheimer representation, is presented. Six electronic states 1,2 (2)Σ(g)(+), 1,2 (2)Σ(u)(+), 1 (2)Π(g), and 1 (2)Π(u) are of relevance in this simulation and have been included. The dependences of the fragmental dissociation probabilities and kinetic energy release (KER) spectra on pulse width, peak intensity, polarization angle, wavelength, and initial vibrational level are analyzed to interpret the influence of control parameters of the external field. Three main dissociation channels, 1 (2)Σ(g)(+) (m = -1), 2 (2)Σ(g)(+) (m = -2), and 2 (2)Σ(u)(+) (m = -3), are seen to dominate the dissociation processes under a wide variety of laser conditions and give rise to well separated groups of KER features. Different dissociation mechanisms for the involved Floquet channels are discussed.

Dissipative and nonunitary solutions of operator commutation relations

NASA Astrophysics Data System (ADS)

Makarov, K. A.; Tsekanovskii, E.

2016-01-01

We study the (generalized) semi-Weyl commutation relations UgAU* g = g(A) on Dom(A), where A is a densely defined operator and G ∋ g ↦ Ug is a unitary representation of the subgroup G of the affine group G, the group of affine orientation-preserving transformations of the real axis. If A is a symmetric operator, then the group G induces an action/flow on the operator unit ball of contracting transformations from Ker(A* - iI) to Ker(A* + iI). We establish several fixed-point theorems for this flow. In the case of one-parameter continuous subgroups of linear transformations, self-adjoint (maximal dissipative) operators associated with the fixed points of the flow yield solutions of the (restricted) generalized Weyl commutation relations. We show that in the dissipative setting, the restricted Weyl relations admit a variety of representations that are not unitarily equivalent. For deficiency indices (1, 1), the basic results can be strengthened and set in a separate case.

Detection of fungal damaged popcorn using image property covariance features

USDA-ARS?s Scientific Manuscript database

Covariance-matrix-based features were applied to the detection of popcorn infected by a fungus that cause a symptom called “blue-eye.” This infection of popcorn kernels causes economic losses because of their poor appearance and the frequently disagreeable flavor of the popped kernels. Images of ker...

Burbank and Shkaplerov playing musical instruments

NASA Image and Video Library

2012-04-21

ISS030-E-267658 (21 April 2012) --- NASA astronaut Dan Burbank, Expedition 30 commander, plays a guitar, while Russian cosmonaut Anton Shkaplerov, flight engineer, plays a musical keyboard during off-time in the Unity node of the International Space Station.

Burbank and Shkaplerov with musical instruments

NASA Image and Video Library

2012-04-21

ISS030-E-267652 (21 April 2012) --- NASA astronaut Dan Burbank (with guitar), Expedition 30 commander, and Russian cosmonaut Anton Shkaplerov, flight engineer, are pictured at a musical keyboard during off-time in the Unity node of the International Space Station.

Burbank and Shkaplerov playing musical instruments

NASA Image and Video Library

2012-04-21

ISS030-E-267651 (21 April 2012) --- NASA astronaut Dan Burbank, Expedition 30 commander, plays a guitar, while Russian cosmonaut Anton Shkaplerov, flight engineer, plays a musical keyboard during off-time in the Unity node of the International Space Station.

Shkaplerov works with EVA Hardware in the SM

NASA Image and Video Library

2012-02-03

ISS030-E-061157 (3 Feb. 2012) --- Russian cosmonaut Anton Shkaplerov, Expedition 30 flight engineer, works with extravehicular activity (EVA) hardware in the Zvezda Service Module of the International Space Station in preparation for an EVA scheduled for Feb. 16, 2012.

Temperature dependence of the photodissociation of CO2 from high vibrational levels: 205-230 nm imaging studies of CO(X1Σ+) and O(3P, 1D) products

NASA Astrophysics Data System (ADS)

Sutradhar, S.; Samanta, B. R.; Samanta, A. K.; Reisler, H.

2017-07-01

The 205-230 nm photodissociation of vibrationally excited CO2 at temperatures up to 1800 K was studied using Resonance Enhanced Multiphoton Ionization (REMPI) and time-sliced Velocity Map Imaging (VMI). CO2 molecules seeded in He were heated in an SiC tube attached to a pulsed valve and supersonically expanded to create a molecular beam of rotationally cooled but vibrationally hot CO2. Photodissociation was observed from vibrationally excited CO2 with internal energies up to about 20 000 cm-1, and CO(X1Σ+), O(3P), and O(1D) products were detected by REMPI. The large enhancement in the absorption cross section with increasing CO2 vibrational excitation made this investigation feasible. The internal energies of heated CO2 molecules that absorbed 230 nm radiation were estimated from the kinetic energy release (KER) distributions of CO(X1Σ+) products in v″ = 0. At 230 nm, CO2 needs to have at least 4000 cm-1 of rovibrational energy to absorb the UV radiation and produce CO(X1Σ+) + O(3P). CO2 internal energies in excess of 16 000 cm-1 were confirmed by observing O(1D) products. It is likely that initial absorption from levels with high bending excitation accesses both the A1B2 and B1A2 states, explaining the nearly isotropic angular distributions of the products. CO(X1Σ+) product internal energies were estimated from REMPI spectroscopy, and the KER distributions of the CO(X1Σ+), O(3P), and O(1D) products were obtained by VMI. The CO product internal energy distributions change with increasing CO2 temperature, suggesting that more than one dynamical pathway is involved when the internal energy of CO2 (and the corresponding available energy) increases. The KER distributions of O(1D) and O(3P) show broad internal energy distributions in the CO(X1Σ+) cofragment, extending up to the maximum allowed by energy but peaking at low KER values. Although not all the observations can be explained at this time, with the aid of available theoretical studies of CO2 VUV

ISS Expedition 42 Crew Profile, Version 2

NASA Image and Video Library

2014-11-26

Narrated production with biographical information about ISS Expedition 42 crewmembers Barry "Butch" Wilmore, Alexander Samokutyaev, Elena Serova, Terry Virts, Anton Shkaplerov and Samantha Cristoforetti. The program covers the crewmember's career including childhood photographs, previous space missions and interview sound bites with the crewmembers.

Shkaplerov makes a selection from food container

NASA Image and Video Library

2012-02-03

ISS030-E-117515 (3 Feb. 2012) --- Russian cosmonaut Anton Shkaplerov, Expedition 30 flight engineer, makes a selection from a food storage container in the Zvezda Service Module of the International Space Station. NASA astronaut Dan Burbank, commander, is visible in the background.

Catholic Women's Colleges in America.

ERIC Educational Resources Information Center

Schier, Tracy, Ed.; Russett, Cynthia, Ed.

The chapters in this collection provide a comprehensive history of Catholic women's colleges in the United States and how they have met the challenges of broader educational change. The chapters are: (1) "Faith, Knowledge, and Gender" (Jill Ker Conway); (2) "Colleges of Religious Women's Congregations: The Spiritual Heritage" (Monika K. Hellwig);…

Creation of Emergent Sandbar Habitat (ESH) in the Headwaters of Lewis and Clark Lake and the Impacts on Water Quality

DTIC Science & Technology

2009-04-01

probably tich in decayed vegetative matter (i.e., humus ) and seed stock. The richness of the matetial is indicated by its ctru·ker color as shown in...iron and manganese), humus and peat materials, plankton, weeds, and industrial wastes (APHA, 1998). “True color” is the color of water from which

Reconstructing Operational Theory: A Framework for Emerging Threats in a Complex Environment

DTIC Science & Technology

2007-01-01

General Shimon Naveh. While the composition and construction of the urban environment traditionally influence targeting calculus , this is not the same as... Anton . "The Relevance of Chaos Theory to Operations." Australian Defense Force Journal. No. 162. Sep/Oct 2003, 4-18. Lind, William

Expedition 54-55 Crew Launches to the Space Station

NASA Image and Video Library

2017-12-17

Expedition 54-55 Soyuz Commander Anton Shkaplerov of Roscosmos and Flight Engineers Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) launched to space on the Russian Soyuz MS-07 spacecraft on Dec. 17 from the Baikonur Cosmodrome in Kazakhstan.

Distribution of Barley yellow dwarf virus-PAV in the Sub-Antarctic Kerguelen Islands and Characterization of Two New Luteovirus Species

PubMed Central

Svanella-Dumas, Laurence; Candresse, Thierry; Hullé, Maurice; Marais, Armelle

2013-01-01

A systematic search for viral infection was performed in the isolated Kerguelen Islands, using a range of polyvalent genus-specific PCR assays. Barley yellow dwarf virus (BYDV) was detected in both introduced and native grasses such as Poa cookii. The geographical distribution of BYDV and its prevalence in P. cookii were analyzed using samples collected from various sites of the archipelago. We estimate the average prevalence of BYDV to be 24.9% in P. cookii, with significant variability between sites. BYDV genetic diversity was assessed using sequence information from two genomic regions: the P3 open reading frame (ORF) (encoding the coat protein) and the hypervariable P6 ORF region. The phylogenetic analysis in the P3 region showed that BYDV sequences segregate into three major lineages, the most frequent of which (Ker-I cluster) showed close homology with BYDV-PAV-I isolates and had very low intra-lineage diversity (0.6%). A similarly low diversity was also recorded in the hypervariable P6 region, suggesting that Ker-I isolates derive from the recent introduction of BYDV-PAV-I. Divergence time estimation suggests that BYDV-PAV-I was likely introduced in the Kerguelen environment at the same time frame as its aphid vector, Rhopalosiphum padi, whose distribution shows good overlap with that of BYDV-Ker-I. The two other lineages show more than 22% amino acid divergence in the P3 region with other known species in the BYDV species complex, indicating that they represent distinct BYDV species. Using species-specific amplification primers, the distribution of these novel species was analyzed. The high prevalence of BYDV on native Poaceae and the presence of the vector R. padi, raises the question of its impact on the vulnerable plant communities of this remote ecosystem. PMID:23825645

76 FR 14051 - Notice of Inventory Completion: San Francisco State University, San Francisco, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-15

..., pursuant to 25 U.S.C. 3001(2), that there is a relationship of shared group identity that can be reasonably... the Tubatulabals of Kern Valley, a non-Federally recognized Indian group. On an unknown date, human remains representing a minimum of one individual were removed from an unknown site (Ca-Ker-UNK (Lake...

High-throughput microarray mapping of cell wall polymers in roots and tubers during the viscosity-reducing process.

PubMed

Huang, Yuhong; Willats, William G; Lange, Lene; Jin, Yanling; Fang, Yang; Salmeán, Armando A; Pedersen, Henriette L; Busk, Peter Kamp; Zhao, Hai

2016-01-01

Viscosity reduction has a great impact on the efficiency of ethanol production when using roots and tubers as feedstock. Plant cell wall-degrading enzymes have been successfully applied to overcome the challenges posed by high viscosity. However, the changes in cell wall polymers during the viscosity-reducing process are poorly characterized. Comprehensive microarray polymer profiling, which is a high-throughput microarray, was used for the first time to map changes in the cell wall polymers of sweet potato (Ipomoea batatas), cassava (Manihot esculenta), and Canna edulis Ker. over the entire viscosity-reducing process. The results indicated that the composition of cell wall polymers among these three roots and tubers was markedly different. The gel-like matrix and glycoprotein network in the C. edulis Ker. cell wall caused difficulty in viscosity reduction. The obvious viscosity reduction of the sweet potato and the cassava was attributed to the degradation of homogalacturonan and the released 1,4-β-d-galactan and 1,5-α-l-arabinan. © 2015 International Union of Biochemistry and Molecular Biology, Inc.

Extending the Phase Zero Campaign Mindset

DTIC Science & Technology

2007-01-01

activities would automatically take U.S. forces out of the fight in current operations. Instead, it would improve the calculus of the Government’s...ndu.edu Liaison officer  for U.S. State  Department  training Iraqi  police Fleet Combat Camera, Pacific (Martin Anton Edgil) Extending the Phase

Africom’s Dilemma: The Global War on Terrorism, Capacity Building, Humanitarianism, and the Future of U.S. Security Policy in Africa

DTIC Science & Technology

2007-11-01

insurgencies are ameliorated through a radical new calculus of effort: 80 percent political, diplomatic, developmental, and informational; and 20...to Hunt al-Qaeda in Africa,” p. A1. 69 167. Anton Menning, “CJTF HOA: Long Term Solutions to Combating Terrorism,” The Leavenworth Times, August

Weight Measurements and Standards for Military Personnel

DTIC Science & Technology

2008-09-01

Food Photography Method (RFPM) for use in free-living conditions. When using the RFPM, participants take photographs of their food selection and...children. Obesity, 15, 906-917, 2007. 6. Martin, C., Han, H., Coulon, S., Allen, H., & Anton, S. (2008). The Remote Food Photography Method: An

Burbank trims Shkaplero's hair in the Node 3

NASA Image and Video Library

2011-12-18

ISS030-E-012660 (18 Dec. 2011) --- NASA astronaut Dan Burbank, Expedition 30 commander, trims the hair of Russian cosmonaut Anton Shkaplerov, flight engineer, in the Tranquility node of the International Space Station. Burbank used hair clippers fashioned with a vacuum device to garner freshly cut hair.

Burbank trims Shkaplerov's hair in the Node 3

NASA Image and Video Library

2012-03-18

ISS030-E-161707 (18 March 2012) --- NASA astronaut Dan Burbank, Expedition 30 commander, trims the hair of Russian cosmonaut Anton Shkaplerov, flight engineer, in the Tranquility node of the International Space Station. Burbank used hair clippers fashioned with a vacuum device to garner freshly cut hair.

Shkaplerov trims Burbank's hair in the Node 3

NASA Image and Video Library

2011-12-18

ISS030-E-012655 (18 Dec. 2011) --- Russian cosmonaut Anton Shkaplerov, Expedition 30 flight engineer, trims the hair of NASA astronaut Dan Burbank, commander, in the Tranquility node of the International Space Station. Shkaplerov used hair clippers fashioned with a vacuum device to garner freshly cut hair.

The Democratic School and the Pedagogy of Janusz Korczak: A Model of Early Twentieth Century Reform in Modern Israel

ERIC Educational Resources Information Center

Engel, Liba H.

2013-01-01

This article explores the history and pedagogy of Janusz Korczak within the context of his contemporary early Twentieth-Century European Innovative Educators which include Maria Montessori, Homer Lane, A.S. Neill, and Anton Semyonovitch Makarenko. The pedagogies of the aforementioned are compared and contrasted within the literature.

Volumetric Properties, Viscosities, and Refractive Indices of the Binary Systems 1-Butanol + PEG 200, + PEG 400, and + TEGDME

NASA Astrophysics Data System (ADS)

Živković, N.; Šerbanović, S.; Kijevčanin, M.; Živković, E.

2013-06-01

Densities, viscosities, and refractive indices of three binary systems consisting of 1-butanol with polyethylene glycols of different molecular weights (PEG 200 and PEG 400) or tetraethylene glycol dimethyl ether (TEGDME) were measured at ten temperatures (288.15, 293.15, 298.15, 303.15, 308.15, 313.15, 318.15, 323.15, 328.15, and 333.15) K and atmospheric pressure. Densities of the selected binary mixtures were measured with an Anton Paar DMA 5000 digital vibrating U-tube densimeter, refractive indices were measured with an automatic Anton Paar RXA-156 refractometer, while for viscosity measurements, a digital Stabinger SVM 3000/G2 viscometer was used. From these data, excess molar volumes were calculated and fitted to the Redlich-Kister equation. The obtained results have been analyzed in terms of specific molecular interactions and mixing behavior between mixture components, as well as the influence of temperature on them. Viscosity data were also correlated by Grunberg-Nissan, Eyring-UNIQUAC, three-body McAlister, and Eyring-NRTL models.

Submillisecond Optical Knife-Edge Testing

NASA Technical Reports Server (NTRS)

Thurlow, P.

1983-01-01

Fast computer-controlled sampling of optical knife-edge response (KER) signal increases accuracy of optical system aberration measurement. Submicrosecond-response detectors in optical focal plane convert optical signals to electrical signals converted to digital data, sampled and feed into computer for storage and subsequent analysis. Optical data are virtually free of effects of index-of-refraction gradients.

Final Evaluation of MIPS M/500

DTIC Science & Technology

1987-11-01

recognizing common subexpressions by changing the code to read: acke (n,m) If (, - 0) return *+I; return a ker(n-1, 0 ? 1 aaker (n,.-1)); I the total code...INSTITUTE JPO PTTTSBURCH. PA 15213 N/A N/A N/O 11 TITLE (Inciude Security Class.iication) Final Evaluation of MIPS M/500 12. PERSONAL AUTHOR(S) Daniel V

The College Adjustment Questionnaire: A Measure of Students' Educational, Relational, and Psychological Adjustment to the College Environment

ERIC Educational Resources Information Center

O'Donnell, Maeve B.; Shirley, Lauren A.; Park, Stacey S.; Nolen, Julian P.; Gibbons, Alyssa M.; Rosén, Lee A.

2018-01-01

Several instruments exist to measure college adjustment: the Student Adaptation to College Questionnaire (SACQ; Baker & Siryk, 1989), the College Adjustment Rating Scale (Zitzow, 1984), and the College Adjustment Scales (Anton & Reed, 1991). Of these, the SACQ is the most widely used and takes a multifaceted approach to measuring college…

A Comprehensive Officer Sabbatical Program: Rethinking the Military Officer Career Path

DTIC Science & Technology

2009-04-09

attractive in the civilian world. However, retaining junior officers is more than just a calculus based upon raw numbers. The Army needs to keep...personal knowledge obtained on Anton Myrer Army Leader Day at U.S. Army War College on October 15, 2008 during discussions with Army Senior Leadership

Integrative Education: Teaching Psychology with the Use of Literature and Informational Technology

ERIC Educational Resources Information Center

Toom, Anna

2013-01-01

In this work, a new method of teaching psychology based on the union of scientific, artistic, and information-technological knowledge is presented. The author teaches Cognitive Development in Early Childhood analyzing Anton Chekhov's short story "Grisha" and uses both traditional and computerized instructional methodology. In the authors' two…

York Papers in Linguistics 14.

ERIC Educational Resources Information Center

Harlow, S. J., Ed.; Warner, A. R., Ed.

Papers on a variety of linguistic topics include six papers from a Festschrift and nine others, as follows: "Attitudes Towards English as a Possible Lingua Franca in Switzerland" (Urs Durmuller); "Functional Stability and Structural Levelling of Dialects: The Case of Maastricht" (Anton M. Hagen, Henk Munstermann); "On the…

Effectiveness of Graduate Training in School Psychology: Perspectives of Graduate Practitioners

ERIC Educational Resources Information Center

Satchwell, Mary Susan

2013-01-01

While trends in graduate training in school psychology indicate a movement towards an increasing emphasis on consultation and decreasing emphasis on assessment (Anton-LaHart & Rosenfield, 2004), there remains a gap between training and practice for professional school psychologists (Harrison, et al., 2004). The present study provided an…

Robotics Competitions and Science Classrooms

ERIC Educational Resources Information Center

Benke, Gertraud

2012-01-01

This paper looks at the distinctions between science classrooms and the robotics competition described in the article "Examining the mediation of power in a collaborative community: engaging in informal science as authentic practice" written by Anton Puvirajah, Geeta Verma and Horace Webb. Using the framework of "productive disciplinary…

State of the Modern Information Professional, 1992-1993. An International View of the State of the Information Professional and the Information Profession in 1992-1993. FID Occasional Paper 4.

ERIC Educational Resources Information Center

International Federation for Information and Documentation, The Hague (Netherlands).

The following 14 papers are provided: (1) "Perfil del profesional de la informacion en Venezuela" with a synopsis in English: "Profile of the Information Professional in Venezuela" (A. D. Anton and M. S. de Arenas); (2) "The Modern Information Professional in the Caribbean Setting" (D. Douglas); (3) "Development…

NATO Enlargement and Democratic Control of the Armed Forces: The Experience of Poland and Implications for Neighboring "Partnership for Peace" Countries.

DTIC Science & Technology

1998-03-01

borders. You do not follow our suggestions, and we feel threatened...we are 88 See Hannah Arendt , "Reflections on the Hungarian Revolution," Journal of...Press, 1977). Arendt , Hanna, "Reflections on the Hungarian Revolution," Journal of Politics 20.1 (February 1958). Bebler, Anton A., "Postscript" in

Physical Layer Ethernet Clock Synchronization

DTIC Science & Technology

2010-11-01

42 nd Annual Precise Time and Time Interval (PTTI) Meeting 77 PHYSICAL LAYER ETHERNET CLOCK SYNCHRONIZATION Reinhard Exel, Georg...oeaw.ac.at Nikolaus Kerö Oregano Systems, Mohsgasse 1, 1030 Wien, Austria E-mail: nikolaus.keroe@oregano.at Abstract Clock synchronization ...is a service widely used in distributed networks to coordinate data acquisition and actions. As the requirement to achieve tighter synchronization

Trust-Management, Intrusion-Tolerance, Accountability, and Reconstitution Architecture (TIARA)

DTIC Science & Technology

2009-12-01

Tainting, tagged, metadata, architecture, hardware, processor, microkernel , zero-kernel, co-design 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF... microkernels (e.g., [27]) embraced the idea that it was beneficial to reduce the ker- nel, separating out services as separate processes isolated from...limited adoption. More recently Tanenbaum [72] notes the security virtues of microkernels and suggests the modern importance of security makes it

Bismaleimide/Preceramic Polymer Blends for Hybrid Material Transition Regions. Part 1. Processing and Characterization (Postprint)

DTIC Science & Technology

2014-01-01

and placed in a bea- ker with a silicone oil bath at 150C for 10 min while slowly adding the component A of the Matrimid A/B pow- der. To prepare the... pyrolytic cera- mic conversion reaction that was essentially completed at 700C. The observed 62% char yield for RD-730 is reason- ably close to the 67

The Miami Linguistic Reading Program, 1965-1968. Report.

ERIC Educational Resources Information Center

Digneo, Ellen Hartnett, Ed.; Shaya, Tila, Ed.

Information related to the implementation of the Miami Linguistic Reading Program for Spanish-speaking and American Indian children in 6 New Mexico school systems is presented. School systems utilizing and reporting on the program are: (1) the West Las Vegas School System; (2) Anton Chico Elementary School in Santa Rosa; (3) Pojoaque Valley…

Landmarks in the Literature: Super Soviet Pedagogue.

ERIC Educational Resources Information Center

Alston, Patrick L.

1979-01-01

Anton Makarenko became a national hero for effecting education for communism in the 1920s. His book, "The Road to Life," is an artistic achievement and the most widely read and influential work on education in the Soviet Union. But Makarenko's legacy is more myth than model in present-day Russia. (Author/SJL)

Ocean Engineering Studies Compiled 1991. Volume 10. External Pressure Housing - Concrete

DTIC Science & Technology

1991-01-01

Hafsklold Ing. F. Selmer AS Anton Brandtzaeg Post Office Box 256 Professor of Construction & Harbour Oslo, Norway Engineering Norwegian Technical University...1984, pp 364-411. 50. 0. Olsen , "Implosion analysis of concrete cylinders under hydro- static pressure," ACI, vol 75, no. 3, Mar 1973, pp 82-85. 51. K.P

Adaptive Identification by Systolic Arrays.

DTIC Science & Technology

1987-12-01

BIBLIOGRIAPHY Anton , Howard, Elementary Linear Algebra , John Wiley & Sons, 19S4. Cristi, Roberto, A Parallel Structure Jor Adaptive Pole Placement...10 11. SYSTEM IDENTIFICATION M*YETHODS ....................... 12 A. LINEAR SYSTEM MODELING ......................... 12 B. SOLUTION OF SYSTEMS OF... LINEAR EQUATIONS ......... 13 C. QR DECOMPOSITION ................................ 14 D. RECURSIVE LEAST SQUARES ......................... 16 E. BLOCK

Russian State Commission Meeting and Final ISS Expedition 54-55 Crew News Conference

NASA Image and Video Library

2017-12-16

In preparation for launch, the final meeting between the Russian State Commission and the crew of International Space Station Expedition 54-55 meets in Baikonur, Kazakhstan. Prime crew members are Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA), Anton Shkaplerov the Russian Federal Space Agency (Roscosmos) and Scott Tingle of NASA.

Convergence and reproducibility in molecular dynamics simulations of the DNA duplex d(GCACGAACGAACGAACGC).

PubMed

Galindo-Murillo, Rodrigo; Roe, Daniel R; Cheatham, Thomas E

2015-05-01

The structure and dynamics of DNA are critically related to its function. Molecular dynamics simulations augment experiment by providing detailed information about the atomic motions. However, to date the simulations have not been long enough for convergence of the dynamics and structural properties of DNA. Molecular dynamics simulations performed with AMBER using the ff99SB force field with the parmbsc0 modifications, including ensembles of independent simulations, were compared to long timescale molecular dynamics performed with the specialized Anton MD engine on the B-DNA structure d(GCACGAACGAACGAACGC). To assess convergence, the decay of the average RMSD values over longer and longer time intervals was evaluated in addition to assessing convergence of the dynamics via the Kullback-Leibler divergence of principal component projection histograms. These molecular dynamics simulations-including one of the longest simulations of DNA published to date at ~44μs-surprisingly suggest that the structure and dynamics of the DNA helix, neglecting the terminal base pairs, are essentially fully converged on the ~1-5μs timescale. We can now reproducibly converge the structure and dynamics of B-DNA helices, omitting the terminal base pairs, on the μs time scale with both the AMBER and CHARMM C36 nucleic acid force fields. Results from independent ensembles of simulations starting from different initial conditions, when aggregated, match the results from long timescale simulations on the specialized Anton MD engine. With access to large-scale GPU resources or the specialized MD engine "Anton" it is possible for a variety of molecular systems to reproducibly and reliably converge the conformational ensemble of sampled structures. This article is part of a Special Issue entitled: Recent developments of molecular dynamics. Copyright © 2014. Published by Elsevier B.V.

Structural inheritance and selective reactivation in the central Andes: Cenozoic deformation guided by pre-Andean structures in southern Peru

NASA Astrophysics Data System (ADS)

Perez, Nicholas D.; Horton, Brian K.; Carlotto, Victor

2016-03-01

Structural, stratigraphic, and geochronologic constraints from the Eastern Cordillera in the central Andean plateau of southern Peru (14-15°S) demonstrate the existence and position of major pre-Andean structures that controlled the accumulation of Triassic synrift fill and guided subsequent Cenozoic deformation. The timing of initial clastic deposition of the Triassic Mitu Group is here constrained to ~ 242-233 Ma on the basis of detrital and volcanic zircon U-Pb geochronology. Regionally distinct provenance variations, as provided by U-Pb age populations from localized synrift accumulations, demonstrate Triassic erosion of multiple diagnostic sources from diverse rift-flank uplifts. Stratigraphic correlations suggest synchronous initiation of extensional basins containing the Mitu Group, in contrast with previous interpretations of southward rift propagation. Triassic motion along the NE-dipping San Anton normal fault accommodated up to 7 km of throw and hanging-wall deposition of a synrift Mitu succession > 2.5 km thick. The contrasting orientation of a non-reactivated Triassic normal fault suggests selective inversion of individual structures in the Eastern Cordillera was dependent on fault dip and strike. Selective preservation of a ~ 4 km thick succession of Carboniferous-Permian strata in the down-dropped San Anton hanging wall, beneath the synrift Mitu Group, suggests large-scale erosional removal in the uplifted footwall. Field and map observations identify additional pre-Andean thrust faults and folds attributed to poorly understood Paleozoic orogenic events preserved in the San Anton hanging wall. Selective thrust reactivation of normal and reverse faults during later compression largely guided Cenozoic deformation in the Eastern Cordillera. The resulting structural compartmentalization and across-strike variations in kinematics and deformation style highlight the influence of inherited Paleozoic structures and Triassic normal faults on the long

The Way of the Drum: When Earth Becomes Heart.

ERIC Educational Resources Information Center

Antone, Grafton; Turchetti, Lois Provost

Two Native people describe their respective journeys to healing, journeys that involved the rediscovery of language and culture. In Part I, "Healing the Tears of Yesterday by the Drum Today: The Oneida Language Is a Healing Medicine" (Grafton Antone), the first narrator taught the Oneida language to adult students at a community center.…

Biological Basis for Chemoprevention of Ovarian Cancer. Addendum

DTIC Science & Technology

2007-10-01

Campbell I, Chang-Claude J, Peel D, Anton-Culver H, Berchuck A, Schildkraut J, Whittemore A, McGuire V, DiCioccio RA, Duffy D, Chenevix-Trench G...promotor polymorphism and ovarian cancer risk. Int J Cancer 2000;86:436–9. 23. Menin C, Banna GL, De Salvo G, et al. Lack of association between

Biological Basis for Chemoprevention of Ovarian Cancer

DTIC Science & Technology

2006-10-01

2005;16:955-63. 11) Kelemen L, James M, Spurdle A, Campbell I, Chang-Claude J, Peel D, Anton-Culver H, Berchuck A, Schildkraut J, Whittemore A...X., Abbazadegan, M., et al. CYP17 promotor polymorphism and ovarian cancer risk. Intl J Cancer. 2000; 86: 436-9. 23.Menin, C., Banna , G. L., De

Teaching Translation and Interpreting in Slovakia: Is There Anything Other than Levý and Popovic?

ERIC Educational Resources Information Center

Biloveský, Vladimír; Djovcoš, Martin

2016-01-01

Institutional translation and interpreting training has a long lasting tradition in Slovakia mainly thanks to such significant translation scholars as Anton Popovic, František Miko, Ján Vilikovský and many others. However the situation has changed after the Velvet Revolution in 1989 and the education needed to start adapting to the new market…

How to Select a Good Training-data Subset for Transcription: Submodular Active Selection for Sequences

DTIC Science & Technology

2009-01-01

selection and uncertainty sampling signif- icantly. Index Terms: Transcription, labeling, submodularity, submod- ular selection, active learning , sequence...name of batch active learning , where a subset of data that is most informative and represen- tative of the whole is selected for labeling. Often...representative subset. Note that our Fisher ker- nel is over an unsupervised generative model, which enables us to bootstrap our active learning approach

Ice cream

NASA Image and Video Library

2015-04-20

ISS043E125774 (04/20/2015) --- NASA astronaut Scott Kelly gives the "high sign" on the quality of his snack while taking a break from his work schedule aboard the International Space Station on Apr. 20, 2015. Russian cosmonaut Anton Shkaplerov (ROSCOSMOS) seems to agree on the tasty factor of the specially prepared space food.

Birthday party

NASA Image and Video Library

2015-04-26

ISS043E142528 (04/26/2015) ---From the International Space Station NASA astronaut Terry Virts (right) tweeted this image of he and his crewmate Russian cosmonaut Anton Shkaplerov celebrating the birthday of ESA (European Space Agency) astronaut Samantha Cristoforetti (middle). His tweet commented: "Happy Birthday @AstroSamantha! We had a great time celebrating as a crew."

Shkaplerov participates in a CHeCS Medical Contingency Drill in the U.S. Laboratory

NASA Image and Video Library

2011-12-16

ISS030-E-012600 (16 Dec. 2011) --- Russian cosmonaut Anton Shkaplerov, Expedition 30 flight engineer, participates in a Crew Health Care System (CHeCS) medical contingency drill in the Destiny laboratory of the International Space Station. This drill gives crew members the opportunity to work as a team in resolving a simulated medical emergency onboard the space station.

Better Steganalysis (BEST) - Reduction of Interfering Influence of Image Content on Steganalysis

DTIC Science & Technology

2009-10-08

LSB embedding, let us consider greyscale images with pixel values in the range 0. . . 255 as carrier medium. LSB steganography replaces the least...Detecting LSB steganography in color and grayscale images . IEEE Multimedia, 8(4):22–28, 2001. [9] Jessica Fridrich, Miroslav Goljan, and Dorin Hogea...January, 19–22 2004. [13] Andrew D. Ker. Improved detection of LSB steganography in grayscale images . In Jessica Fridrich, editor, Information Hiding

Extensibility Experiments with the Software Life-Cycle Support Environment

DTIC Science & Technology

1991-11-01

APRICOT ) and Bit- Oriented Message Definer (BMD); and three from the Ada Software Repository (ASR) at White Sands-the NASA/Goddard Space Flight Center...Graphical Kernel System (GKS). c. AMS - The Automated Measurement System tool supports the definition, collec- tion, and reporting of quality metric...Ada Primitive Order Compilation Order Tool ( APRICOT ) 2. Bit-Oriented Message Definer (BMD) 3. LGEN: A Language Generator Tool 4. I"ilc Chc-ker 5

Development and Testing of a Two-Stage Hybrid Launcher.

DTIC Science & Technology

1979-10-31

treating as follows: 0 The steel is austenitizeu ( transformed to the austenite phase ) by heating to approximately 8430 C (1550 0 F), then cooling...produce eicner martensite or bainite, so that some ferrite and pearlite are produced; these phases are considerauly softer and weaKer. To complicate...nigher in alloying elements torn the harder martensite , and the regions lower in these elements form the softer bainite and ferrite . The mechanical

17. 'BIRDSEYEVIEW, PRESIDIO OF MONTEREY, CAL., JAN. 1938.' No signature, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

17. 'BIRDSEYEVIEW, PRESIDIO OF MONTEREY, CAL., JAN. 1938.' No signature, photographer probably Anton C. Heidrick. This panoramic view looks west over Soldier Field from the upper floor or roof of the gymnasium. Original cool toned silver gelatin print measures 85.1 cm by 22.4 cm, flush mounted on mat board. - Presidio of Monterey, Soldier Field, Monterey, Monterey County, CA

14. 'TROOP A, OREGON CAVALRY IN CAMP AT PRESIDIO OF ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. 'TROOP A, OREGON CAVALRY IN CAMP AT PRESIDIO OF MONTEREY, CALIFORNIA, 1915.' Anton C. Heidrick, photographer. This panoramic view looks west from the lower end of Soldier Field, before construction of walls and roads. Original warm toned silver gelatin print measures 94.9 cm by 19.7 cm, flush mounted on mat board. - Presidio of Monterey, Soldier Field, Monterey, Monterey County, CA

ISS Expedition 42 / 43 Soyuz Spacecraft and Crew Preparations for Launch

NASA Image and Video Library

2014-11-26

NASA TV (NTV) video file of crewmembers Terry Virts, Anton Shkaplerov (Roskosmos) and Samantha Cristoforetti (ESA) during final fit check of the Soyuz TMA 15M spacedraft at the Integration Facility, Baikonurk, Kazakhstan. Includes footage of the crew climbing into the Soyuz spacecraft, interviews, visit to museum where the crew sign posters and a flag; flag raising ceremony; and visit to mating facility.

iss042e306480

NASA Image and Video Library

2015-03-07

ISS042E306480 (03/07/2015) --- A meeting of the minds aboard the International Space Station on Mar. 7, 2015 with members of Expedition 42; astronauts US, Barry Wilmore (Commander) Top, Upside down, to the right cosmonaut Elena Serova, & ESA European Space Agency Samantha Cristoforetti. Bottom center US astronaut Terry Virts, top left cosmonauts Alexander Samokutyaev and Anton Shkaplerov.

Ivanishin participates in a CHeCS Medical Contingency Drill in the U.S. Laboratory

NASA Image and Video Library

2011-12-16

ISS030-E-012604 (16 Dec. 2011) --- Russian cosmonauts Anatoly Ivanishin (foreground) and Anton Shkaplerov, both Expedition 30 flight engineers, participate in a Crew Health Care System (CHeCS) medical contingency drill in the Destiny laboratory of the International Space Station. This drill gives crew members the opportunity to work as a team in resolving a simulated medical emergency onboard the space station.

E-Pals: Examining a Cross-Cultural Writing/Literature Project.

ERIC Educational Resources Information Center

McClanahan, Lauren G.

This paper reports on a case study of a U.S. high school literature class during an e-mail exchange with a high school literature class in Moscow (Russia). During this project, the students in both classrooms read short stories by Anton Chekhov and O'Henry. By using the stories as a catalyst, the students' goal was to help their distant partner to…

Franklin, Lavoisier, and Mesmer: origin of the controlled clinical trial.

PubMed

Herr, Harry W

2005-01-01

In 1784, a Royal Commission headed by Benjamin Franklin and Antoine Lavoisier designed a series of ingenious experiments to debunk France's greatest medical rogue, Anton Mesmer, and his bizarre healing of illnesses based on his bogus theory of animal magnetism. Using intentional subject ignorance and sham interventions to investigate mesmerism, Franklin's commission provided a model for the controlled clinical trial.

Human Factors Research in Aircrew Performance and Training

DTIC Science & Technology

1988-08-01

Eisenhower Avenue, PROGRAM PROJECTA - 9Q TASK WORK UNITELEMENT NO. NO. A79. NO 236 ACCESSION NO Alexandria, VA 22333-5600 63731,6373 A793 132 11. TITLE...Fort RucKer, Alabama, is contributing to the effectiveness of Army aviation by con- ducting a comprehensive human factors research program in supporL...of aircrew perrorindnce and training. The ARIARDA research program encompasses the full scope of Army aviation with projects in support of (a) emerging

An Analysis of Shelf Space Allocation at the Wright-Patterson Air Force Base Commissary.

DTIC Science & Technology

1987-09-01

Company performed a major shelf space allocation study involving 59 of their stores. The study involved planning and executing a shelf by shelf reset...Betty Crocker Chocolate .a9 2 Betty CrocKer Yellow .93 3 Betty Crocker Devils Food .92 4 Betty Crocker Choc . Choc . Chip .94 5 Betty Crocker German...Headquarters Air Force Commissary Services. ACOS Executive Summary. 28 January 19d6. 12. deadquarters Air Force Commissary Services. Store _Layout

RI: Rheology as a Tool for Understanding the Mechanics of Live Ant Aggregations, Part 2

DTIC Science & Technology

2016-11-04

measure rheological properties of biological fluids. Using this machine, we were able to characterize non-Newtonian fluids such as frog saliva...order to measure rheological properties of biological fluids. Using this machine, we were able to characterize non-Newtonian fluids such as frog...GA, 30332 Objective An Anton Parr MCR 501 rheometer was purchased in order to measure rheological properties of biological fluids. Using this

Electro-Optical and Optical Components for Processor to Processor Interconnects

DTIC Science & Technology

2013-04-01

Kwiat and others were instrumental in explicitly co-entangling other properties such as momentum (path) [4]. Others such as Barnett and Zeilinger ...19 4. References: 1. D. Bouwmeester, J.W. Pan, K. Mattle, M. Eibl, H. Weinfurter and A. Zeilinger , “Experimental quantum teleportation...Nature, Vol. 390, 11 December 1997, pp. 575- 579. 2. Jian-Wei Pan, Dik Bouwmeester, Harald Weinfurter, and Anton Zeilinger , “Experimental Entanglement

Complete Genome Sequence of NEB 5-alpha, a Derivative of Escherichia coli K-12 DH5α.

PubMed

Anton, Brian P; Raleigh, Elisabeth A

2016-11-10

Escherichia coli K-12 DH5α is one of the most popular and widely available laboratory strains, but, surprisingly, no complete genome sequence has been publicly available. Here, we report the complete, finished sequence of NEB 5-alpha (DH5α fhuA2). It should serve as a useful reference for researchers working with DH5α. Copyright © 2016 Anton and Raleigh.

Burbank participates in a CHeCS Medical Contingency Drill in the U.S. Laboratory

NASA Image and Video Library

2011-12-16

ISS030-E-012613 (16 Dec. 2011) --- NASA astronaut Dan Burbank (foreground), Expedition 30 commander, and Russian cosmonaut Anton Shkaplerov, flight engineer, participate in a Crew Health Care System (CHeCS) medical contingency drill in the Destiny laboratory of the International Space Station. This drill gives crew members the opportunity to work as a team in resolving a simulated medical emergency onboard the space station.

Burbank participates in a CHeCS Medical Contingency Drill in the U.S. Laboratory

NASA Image and Video Library

2011-12-16

ISS030-E-012609 (16 Dec. 2011) --- NASA astronaut Dan Burbank (foreground), Expedition 30 commander, and Russian cosmonaut Anton Shkaplerov, flight engineer, participate in a Crew Health Care System (CHeCS) medical contingency drill in the Destiny laboratory of the International Space Station. This drill gives crew members the opportunity to work as a team in resolving a simulated medical emergency onboard the space station.

Eurasianism: A Historical and Contemporary Context

DTIC Science & Technology

2015-03-01

Foreign Affairs, March 31, 2014, http://www.foreignaffairs.com/articles/141080/anton-barbashin-and-hannah-thoburn/putins-brain. 2 Dina Newman , “Russian...Eurasianism: An Ideology of Empire (Baltimore: Johns Hopkins Press, 2008), trans. Mischa Gabowitsch, 142. 4 Dina Newman , “Russian Nationalist...Russian Eurasiansim – Historiosophy and Ideology,” 106. 17 his parents were renowned poets) and as such, he faced difficulty in gaining

USAF Summer Research Program - 1993 Graduate Student Research Program Final Reports, Volume 6, AEDC, FJSRL and WHMC

DTIC Science & Technology

1993-12-01

Mechanical Engineering Associate, PhD Laboratory: PL/VT Division Engineering University of Texas, San Anton Vol-Page No: 3-26 San Antonio, TX 7824-9065...parameters. The modules can be primitive or compound. Primitive modules represent the elementary computation units and define their interfaces. The... linear under varying conditions for the range of processor numbers. Discussion Performance: Our evaluation of the performance measurement results is the

Influences on Tobacco Control Funding Decisions: Explaining State Variation in Appropriations

DTIC Science & Technology

2003-01-01

prevent morbidity and mortality and reduce costs in the future (Aldana, 2001; Harris, Holman, Carande- Kulis , 2001). However, health promotion...control is a core public health function with annual funding of national prevention programs, basic and applied research, technical assistance, and...common actions (Anton, 1989). As an example, primary authority for public education resides at the county level, but state and federal governments may

VEG-03 Consmption Harvest no. 1

NASA Image and Video Library

2018-03-11

iss055e001536 (March 8, 2018) --- Expedition 55 Commander Anton Shkaplerov eats a piece of lettuce harvested as part of the ongoing space crop study VEG-03. The botany experiment uses the Veggie plant growth facility to cultivate a type of cabbage, lettuce and mizuna which are harvested on-orbit with some samples consumed by astronauts and others returned to Earth for testing.

Southeast Asia Report.

DTIC Science & Technology

1987-04-01

such as palm oil and coconut oil . In 1985, for example, Malaysia alone exported 470,887 tonnes of palm oil and palm ker- nel oil to the EEC valued...SOUTHEAST ASIA REPORT CONTENTS INTER-ASIAN AFFAIRS ASEAN To Protest EEC Duties on Vegetable Oils , Fats (Hardev Kaur; BUSINESS TIMES, 18 Feb 87) 1...DAN (TAP CHI QUAN DOI NHAN DAN, Dec 86) 112 /12223 - f - ASEAN TO PROTEST EEC DUTIES ON VEGETABLE OILS , FATS Kuala Lumpur BUSINESS TIMES in

Phenylpropanoid derivatives from edible canna, Canna edulis.

PubMed

Yun, Young Sook; Satake, Motoyoshi; Katsuki, Shigeki; Kunugi, Akira

2004-07-01

Two phenylpropanoid sucrose esters were isolated from dry rhizomes of Canna edulis Ker Gawl., along with a known phenylpropanoid sucrose ester and four known phenylpropanoids. On the basis of analysis of spectroscopic data and chemical evidence, these two phenylpropanoid sucrose esters were shown to be 3-O-p-coumaroyl-6-O-feruloyl-beta-D-fructofuranosyl 6-O-acetyl-alpha-D-glucopyranoside and 3,6-di-O-p-coumaroyl-beta-D-fructofuranosyl 6-O-acetyl-alpha-D-glucopyranoside.

Expedition 54 Press Conference

NASA Image and Video Library

2017-12-16

Expedition 54 flight engineer Scott Tingle is seen in quarantine, behind glass, during a press conference, Saturday, Dec. 16, 2017 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Tingle, Soyuz Commander Anton Shkaplerov of Roscosmos, and flight engineer Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) are scheduled to launch to the International Space Station aboard the Soyuz spacecraft from the Baikonur Cosmodrome on December 17. Photo Credit: (NASA/Joel Kowsky)

Next Space Station Crew Prepares for Mission

NASA Image and Video Library

2017-12-01

B-roll footage includes various pre-launch training activities of Expedition 54-55, featuring Soyuz Commander Anton Shkaplerov of Roscosmos and Flight Engineers Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA), as they prepare for their mission to the International Space Station. The trio will launch to the station aboard a Soyuz spacecraft on Dec. 17 from the Baikonur Cosmodrome in Kazakhstan.

Expedition 30 Landing

NASA Image and Video Library

2012-04-28

Expedition 30 Flight Engineer Anatoly Ivanishin is welcomed home by colleagues and family in Star City, Russia on Saturday, April 28, 2012. Russian Cosmonaut Ivanishin, Expedition 30 Commander Daniel Burbank, and Russian Cosmonaut Anton Shkaplerov landed outside of Arkalyk, Kazakhstan earlier in the day from over five months onboard the International Space Station where they served as members of the Expedtion 29 and 30 crews. Photo Credit: (NASA/Carla Cioffi)

Control Strategies for Guided Collective Motion

DTIC Science & Technology

2015-01-30

Control, Atlanta, GA, USA, December 2010, pp. 5468-5473. [19] C. Rorres and H. Anton , “ Elementary linear algebra applications version,” 9th Edition...work addresses and analyses deviated linear cyclic pursuit in which an Distribution Code A: Approved for public release, distribution is unlimited...Pursuit 6. D. Mukherjee and D. Ghose: Deviated Linear Cyclic Pursuit 7. D. Mukherjee and D. Ghose; On Synchronous and Asynchronous Heterogeneous Cyclic

Pulse Height Analyzer Interfacing and Computer Programming in the Environmental Laser Propagation Project

DTIC Science & Technology

1976-06-01

United States Naval Postgraduate School, Monterey , California, 1974. 6. Anton , H., Elementary Linear Algebra , John Wiley & Sons, 1973. 7. Parrat, L. G...CONVERTER ln(laser & bias) PULSE HEIGHT ANALYZER © LINEAR AMPLIFIER SAMPLE TRIGGER OSCILLATOR early ln(laser & bias) SCINTILLOMETERS recent BACKGROUND...DEMODULATOR LASER CALIBRATION BOX LASER OR CAL VOLTAGE LOG CONVERTER LN (LASER OR CAL VOLT) LINEAR AMPLIFIER uLN (LASER OR CAL VOLT) PULSE HEIGHTEN ANALYZER V

Global motions exhibited by proteins in micro- to milliseconds simulations concur with anisotropic network model predictions

NASA Astrophysics Data System (ADS)

Gur, M.; Zomot, E.; Bahar, I.

2013-09-01

The Anton supercomputing technology recently developed for efficient molecular dynamics simulations permits us to examine micro- to milli-second events at full atomic resolution for proteins in explicit water and lipid bilayer. It also permits us to investigate to what extent the collective motions predicted by network models (that have found broad use in molecular biophysics) agree with those exhibited by full-atomic long simulations. The present study focuses on Anton trajectories generated for two systems: the bovine pancreatic trypsin inhibitor, and an archaeal aspartate transporter, GltPh. The former, a thoroughly studied system, helps benchmark the method of comparative analysis, and the latter provides new insights into the mechanism of function of glutamate transporters. The principal modes of motion derived from both simulations closely overlap with those predicted for each system by the anisotropic network model (ANM). Notably, the ANM modes define the collective mechanisms, or the pathways on conformational energy landscape, that underlie the passage between the crystal structure and substates visited in simulations. In particular, the lowest frequency ANM modes facilitate the conversion between the most probable substates, lending support to the view that easy access to functional substates is a robust determinant of evolutionarily selected native contact topology.

Expedition 54 Press Conference

NASA Image and Video Library

2017-12-16

Expedition 54 Soyuz Commander Anton Shkaplerov of Roscosmos is seen in quarantine, behind glass, during a press conference, Saturday, Dec. 16, 2017 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Shkaplerov, flight engineer Scott Tingle of NASA, and flight engineer Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) are scheduled to launch to the International Space Station aboard the Soyuz spacecraft from the Baikonur Cosmodrome on December 17. Photo Credit: (NASA/Joel Kowsky)

Human Respiratory Responses during High Performance Flight

DTIC Science & Technology

1987-11-01

of walking in chemical defence clothing. RAF Institute of Aviation Medicine Aircrew Equipment Group Report No 347 , 1975. 95 Gibson T M, Anton D...1.05 1.01 1.15 1.07 0.0391 0.6223 0.C243 2 Taxy (pre-flight) . 1.00 1.01 1.05 1.08 1.02 0.0296 0.4187 0.0124 1 Jako -oft . 1.09 - 1.13 1.15 1.55 1.14

Weight Measurements and Standards for Soldiers

DTIC Science & Technology

2009-10-01

Dr. Corby Martin has expanded on this technology and has developed the Remote Food Photography Method (RFPM) for use in free-living conditions...Allen HR, Champagne CM, Anton SD. A novel method to remotely measure food intake of free-living individuals in real time: the remote food ... photography method. Br J Nutr. 2009 Feb;101:446-56. 5. Martin CK, Kaya S, Gunturk BK. Quantification of food intake using food image analysis. Conference

ISS Expedition 42 / 43 Crew Training Resource Reel (JSC-2641)

NASA Image and Video Library

2014-11-14

Media resource reel of ISS Expedition 42 / 43 Crew training activities. Includes footage of crew photo shots with Samantha Cristoforetti, Anton Shkaplerov and Terry Virts; Routine shots with Virts, ISS Expedition 43 crewmember Scott Kelly, Cristoforetti, ISS Expedition 41 / 42 crewmember Barry Wilmore; and Shklaplerov; T-38 Operations with Virts; Routine operations with Cristoforetti, Shkaplerov and Virts; Neutral Buoyancy Lab (NBL) with Cristoforetti and Kelly; and Emergency Scenatios with Virts, Cristoforetti and Shkaplerov.

Expedition 30 Landing

NASA Image and Video Library

2012-04-28

Expedition 30 Flight Engineers Anatoly Ivanishin, far left, and Anton Shkaplerov are welcomed home by colleagues and family in Star City, Russia on Saturday, April 28, 2012. Russian Cosmonauts Ivanishin, Shkaplerov and Expedition 30 Commander Daniel Burbank landed outside of Arkalyk, Kazakhstan earlier in the day from over five months onboard the International Space Station where they served as members of the Expedtion 29 and 30 crews. Photo Credit: (NASA/Carla Cioffi)

Conical Lens for 5-Inch/54 Gun Launched Missile

DTIC Science & Technology

1981-06-01

Propagation, Interferenceand Diffraction of Light, 2nd ed. (revised), p. 121-124, Pergamon Press, 1964. 10. Anton , Howard, Elementary Linear Algebra , p. 1-21...equations is nonlinear in x, but is linear in the coefficients. Therefore, the techniques of linear algebra can be used on equation (F-13). The method...This thesis assumes the air to be homogenous, isotropic, linear , time indepen- dent (HILT) and free of shock waves in order to investigate the

Control Strategies for Guided Collective Motion

DTIC Science & Technology

2015-02-27

Rorres and H. Anton , “ Elementary linear algebra applications version,” 9th Edition, Wiley India Pvt. Ltd., 2011. [20] S.H. Strogatz, “From Kuramoto to... linear cyclic pursuit in which an agent pursues its leader with an angle of deviation. The sufficient conditions for the stability of such systems are...Generalized Hierarchical Cyclic Pursuit 6. D. Mukherjee and D. Ghose: Deviated Linear Cyclic Pursuit 7. D. Mukherjee and D. Ghose; On Synchronous and

USSR and Eastern Europe Scientific Abstracts, Electronics and Electrical Engineering, Number 33.

DTIC Science & Technology

1977-09-27

reduces to an infinite system of linear homogeneous algebraic equations and leads to Mathieu functions of the k-th order. The solution is convergent in...cylinder walls to be infinitesimally thin ideal conductors. The problem is reduced to a system of Fredholm linear algebraic equations of the second...EXPECTED DEVELOPMENTS OF TRANSISTORIZED LOW-NOISE MICROWAVE AMPLIFIERS Prague SDELOVACI TECHNIKA in Czech Vol 25, No 2, Feb 77 pp 47-49 TALLO, ANTON

A Search for Mountain Waves in MLS Stratospheric Limb Radiances from the Winter Northern Hemisphere: Data Analysis and Global Mountain Wave Modeling

DTIC Science & Technology

2004-02-11

the general circulation of the middle atmosphere, Philos. Trans. R. Soc. London, Ser. A, 323, 693–705. Anton , H. (2000), Elementary Linear Algebra ...Because the saturated radiances may depend slightly on tangent height as the limb path length decreases, a linear trend (described by parameters a and b...track days and interpolated onto the same limb-track orbits. The color bar scale for radiance variance is linear . (b) Digital elevations of northern

Predicting the Underwater Sound of Moderate and Heavy Rainfall from Laboratory Measurements of Radiation from Single Large Raindrops

DTIC Science & Technology

1992-03-01

Elementary Linear Algebra with Applications, pp. 301- 323, John Wiley and Sons Inc., 1987. Atlas, D., and Ulbrich, C. E. W., "The Physical Basis for...vector drd In this case, the linear system is said to be inconsistent ( Anton and Rorres, 1987). In contrast, for an underdetermined system (where the...ocean acoustical tomography and seismology. In simplest terms, the general linear inverse problem consists of fimding the desired solution to a set of m

Coherent Change Detection: Theoretical Description and Experimental Results

DTIC Science & Technology

2006-08-01

373–376. 47. S. M. Kay, Fundamentals of statistic signal processing. Vol 2. Detection theory. Pren- tice Hall, 1998. 48. H . Anton and C . Rorres ...Proceedings of the 1998 International Geoscience and Remote Sensing Symposium, vol. 5, 1998, pp. 2451–2453. 9. C . V. Jakowatz Jr., D. E. Wahl, P. H . Eichel...dissertation, School of Electrical and Electronic Engineering, The University of Adelaide, 2004. 20. C . H . Gierull, Statistics of SAR interferograms

PKC Epsilon: A Novel Oncogenic Player in Prostate Cancer

DTIC Science & Technology

2014-09-01

cancer. Clin Cancer Res 15: 4799-4805. 3 Neto, A. S., Tobias-Machado, M., Wroclawski, M. L., Fonseca , F. L., Pompeo, A. C., Del Giglio, A. (2010...biological chemistry 268: 6090-6096. 19 Perletti, G. P., Folini, M., Lin, H. C., Mischak, H., Piccinini, F., Tashjian, A. H., Jr. ( 1996 ). Overexpression...7737. 36 Aparicio Gallego, G., Diaz Prado, S., Jimenez Fonseca , P., Garcia Campelo, R., Cassinello Espinosa, J., Anton Aparicio, L. M. (2007

An Integrity Framework for Image-Based Navigation Systems

DTIC Science & Technology

2010-06-01

Anton H. and Rorres C. Elementary Linear Algebra . New York, NY: John Wiley & Sons, Inc., 2000. 4. Arthur T. “The Disparity of Parity, Determining...107. Spilker , James J.J. Digital Communications by Satellite. Englewood Cliffs NJ: Prentice Hall, 1977. 108. Strang G. Linear Algebra and its...2.3 The Linearized and Extended Kalman Filters . . . . . . 22 2.3.1 State and Measurement Model Equations . . . 23 2.3.2 The Linearized Kalman Filter

Anatomy of a Silicon Compiler

DTIC Science & Technology

1994-10-04

Recognition 321 Anton StOWz*e 21.1. ALGORITHM AND ARCHITECTURE ............... 322 21.2. SYSTEM ARCHITECTURE .................... 325 213. CHIP ARCHiTECTURES...age controlled switch. The second is a linear model where each transistor is mod- eled by a voltage controlled switch in series with a resistor, and...the blocks being co- linear . Routing channels separate blocks which are adjacent. Channels are also placed along the top edge of each block in order to

Fantastic Antone Succeeds! Experiences in Educating Children with Fetal Alcohol Syndrome.

ERIC Educational Resources Information Center

Kleinfeld, Judith, Ed.; Wescott, Siobhan, Ed.

Three themes run through the accounts of parents and teachers as they relate their experiences rearing and teaching children with fetal alcohol syndrome (FAS): (1) Children with FAS can achieve far more than current negative stereotypes suggest; (2) Early intervention and excellent family care make an enormous difference to the success and…

A Default Temporal Logic for Regulatory Conformance Checking

DTIC Science & Technology

2008-04-01

proofs. In Section 4.3, we provide an axiomatization using Fitting’s sequent calculus [25]. Completeness is proved in Section 4.4. We conclude, in...axiomatize RefL. 4.3 Sequent Calculus We use Fitting’s sequent calculus [25]. A sequent is a statement of the form Γ → ∆, where Γ and ∆ are finite sets of...T.D., Vail, M.W., Anton , A.I.: Towards regulatory compliance: Extracting rights and obligations to align requirements with regulations. In

jsc2011e203164

NASA Image and Video Library

2011-10-23

At the Kremlin Wall in Moscow, Expedition 30 Commander Dan Burbank of NASA laid flowers October 24, 2011 in a traditional ceremony during the tour of Red Square he and his crewmates conducted prior to their launch to the International Space Station November 14 on the Soyuz TMA-22 spacecraft from the Baikonur Cosmodrome in Kazakhstan. Burbank, Soyuz Commander Anton Shkaplerov and Anatoly Ivanishin will arrive in Baikonur October 31 for final pre-launch preparations. Credit: NASA

Ionic Attachment as a Feasible Approach to Heterogenizing Anionic Solution Catalysts. The Carbonylation of Methanol,

DTIC Science & Technology

1980-08-01

carbonylation of methanol to acetic acid reaction is well suited for a demonstration of the feasibility and value of ionically binding a catalyst to a...approximate doubling of the reaction rate. This result suggests that a liquid flow system design in which there is a large catalyst to methanol ratio could...Heterogenizing Anionic Solution Catalysts . The Carbonylation of Methanol by Russell S. Drago, Eric D. Nyberg, Anton El A’mma and Alan Zombeck ABSTRACT -’Few

Distinct, crucial roles of flavonoids during legume nodulation.

PubMed

Subramanian, Senthil; Stacey, Gary; Yu, Oliver

2007-07-01

RNA interference-mediated silencing of the key flavonoid and isoflavone biosynthesis enzyme, respectively, by two different research groups has provided direct genetic evidence for the essential roles that these compounds play in nodulation. Anton Wasson et al. have shown that flavonoids are essential for localized auxin transport inhibition during nodulation in the indeterminate legume Medicago truncatula. By contrast, Senthil Subramanian et al. have shown that isoflavones are essential for endogenous nod gene induction in the determinate legume soybean.

Naval Research Logistics Quarterly. Volume 28. Number 3,

DTIC Science & Technology

1981-09-01

denotes component-wise maximum. f has antone (isotone) differences on C x D if for cl < c2 and d, < d2, NAVAL RESEARCH LOGISTICS QUARTERLY VOL. 28...or negative correlations and linear or nonlinear regressions. Given are the mo- ments to order two and, for special cases, (he regression function and...data sets. We designate this bnb distribution as G - B - N(a, 0, v). The distribution admits only of positive correlation and linear regressions

An Extended Microcomputer-Based Network Optimization Package.

DTIC Science & Technology

1982-10-01

Analysis, Laxenberq, Austria, 1981, pp. 781-808. 9. Anton , H., Elementary Linear Algebra , John Wiley & Sons, New York, 1977. 10. Koopmans, T. C...fCaRUlue do leVee. aide It 001100"M OW eedea9f’ OF Nooke~e Network, generalized network, microcomputer, optimization, network with gains, linear ...Oboe &111111041 network problem, in turn, can be viewed as a specialization of a linear programuing problem having at most two non-zero entries in each

Application of Artificial Boundary Conditions in Sensitivity-Based Updating of Finite Element Models

DTIC Science & Technology

2007-06-01

is known as the impedance matrix[ ]( )Z Ω . [ ] [ ] 1( ) ( )Z H −Ω = Ω (12) where [ ] 2( )Z K M j C ⎡ ⎤Ω = −Ω + Ω⎣ ⎦ (13) A. REDUCED ORDER...D.L. A correlation coefficient for modal vector analysis. Proceedings of 1st International Modal Analysis Conference, 1982, 110-116. Anton , H ... Rorres , C ., (2005). Elementary Linear Algebra. New York: John Wiley and Sons. Avitable, Peter (2001, January) Experimental Modal Analysis, A Simple

Expedition 42 Crew Wave

NASA Image and Video Library

2014-11-24

Expedition 42 Flight Engineer Samantha Cristoforetti, of the European Space Agency (ESA), top, Flight Engineer Terry Virts of NASA, center, and Soyuz Commander Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos), bottom, wave farewell prior to boarding the Soyuz TMA-15M spacecraft for launch, Monday, Nov. 24, 2014 at the Baikonur Cosmodrome in Kazakhstan. Cristoforetti, Virts, and Shkaplerov will spend the next five and a half months aboard the International Space Station. Photo Credit: (NASA/Aubrey Gemignani)

THE ADVERSE OUTCOME PATHWAY (AOP) FRAMEWORK ...

EPA Pesticide Factsheets

An Adverse Outcome Pathway (AOP) represents the organization of current and newly acquired knowledge of biological pathways. These pathways contain a series of nodes (Key Events, KEs) that when sufficiently altered influence the next node on the pathway, beginning from an Molecular Initiating Event (MIE), through intermediate KEs, ending in an Adverse Outcome (AO) which may be used as a basis for decision making. A KE is a measurable biological change, and is linked with other KEs via Key Event Relationships (KERs). A given KE may be involved in several AOPs, leading to a plausible network of biological changes that are involved in an organism’s response to an external stressor. When describing an AOP, five guiding principles have been proposed [1]: 1) an AOP is not specific to a single external stressor, 2) AOPs are modular, with KEs and KERs that can be used in several AOPs, 3) a single AOP is the unit of development, 4) most biological responses will be the result of networks of AOPs, and 5) AOPs will be modified as more biological knowledge becomes available. The collaborative development of AOPs is recommended to be performed using the AOP-Wiki (https://aopwiki.org), which is an effort between the European Commission – DG Joint Research Centre (JRC) and U.S. Environmental Protection Agency (EPA). The Wiki is one part of a larger OECD-sponsored AOP Knowledgebase effort, which is a repository for all AOPs developed as part of the Organization for Economic

Restrictions of the sale of pharmaceuticals and medical devices such as contact lenses over the internet and the free movement of goods.

PubMed

de Sadeleer, Nicolas

2012-03-01

In the light of new case law development, this article examines whether national restrictions on the online sale of pharmaceuticals and medical devices such as contact lenses are consistent either with EU secondary law, either with Article 34 TFEU that prohibits measures having equivalent effect to quantitative restrictions on imports. In particular, this article focuses on an analysis of two judgments on this important issue delivered by the Court of Justice of the European Union in 2003 and 2010, namely the Deutscher Apothekerverband decision and the Ker-Optika decision.

Operation Plan I-45 ICEBERG

DTIC Science & Technology

1945-02-01

8217COmIIAND OF MAJOR- GENERAL del VALLE: R. O, BARE, Col, USMC, ·C of S. ANNEXES: ABLE - Distribution B1iKER - Intelligence CHARLIE - Naval Gunfire Support Plan...3. ABLE Annex BAKER to Opn Plan 1-45, 1st MarDiv-(Rein) INTELLIGENCE 00015 1st Mar Div (Rein). 1990-5-80 In The Field 475/355 . 1100, 1OFeb, 1945. AP...distributed. (c) JANIS No. 86, August, 1944; JANIS No. 86 (Change 1), October 1944. (d) Engineer Intelligence Information of OKINAWA SHIMA prepared by Eng

Alkylation of an active-site cysteinyl residue during substrate-dependent inactivation of Escherichia coli S-adenosylmethionine decarboxylase.

PubMed

Diaz, E; Anton, D L

1991-04-23

S-Adenosylmethionine decarboxylase from Escherichia coli is a member of a small class of enzymes that uses a pyruvoyl prosthetic group. The pyruvoyl group is proposed to form a Schiff base with the substrate and then act as an electron sink facilitating decarboxylation. We have previously shown that once every 6000-7000 turnovers the enzyme undergoes an inactivation that results in a transaminated pyruvoyl group and the formation of an acrolein-like species from the methionine moiety. The acrolein then covalently alkylates the enzyme [Anton, D. L., & Kutny, R. (1987) Biochemistry 26, 6444]. After reduction of the alkylated enzyme with NaBH4, a tryptic peptide with the sequence Ala-Asp-Ile-Glu-Val-Ser-Thr-[S-(3-hydroxypropyl)Cys]-Gly-Val-Ile-Ser-Pro - Leu-Lys was isolated. This corresponds to acrolein alkylation of a cysteine residue in the second tryptic peptide from the NH2 terminal of the alpha-subunit [Anton, D. L., & Kutny, R. (1987) J. Biol. Chem. 262, 2817-2822]. The modified residue derived is from Cys-140 of the proenzyme [Tabor, C. W., & Tabor, H. (1987) J. Biol. Chem. 262, 16037-16040] and lies in the only sequence conserved between rat liver and E. coli S-adenosylmethionine decarboxylase [Pajunen et al. (1988) J. Biol. Chem. 263, 17040-17049]. We suggest that the alkylated Cys residue could have a role in the catalytic mechanism.

In vivo mechanism-based inactivation of S-adenosylmethionine decarboxylases from Escherichia coli, Salmonella typhimurium, and Saccharomyces cerevisiae.

PubMed

Li, Y F; Hess, S; Pannell, L K; White Tabor, C; Tabor, H

2001-09-11

S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme in the biosynthesis of spermidine and spermine, is first synthesized as a proenzyme, which is cleaved posttranslationally to form alpha and beta subunits. The alpha subunit contains a covalently bound pyruvoyl group derived from serine that is essential for activity. With the use of an Escherichia coli overexpression system, we have purified AdoMetDCs encoded by the E. coli, Saccharomyces cerevisiae, and Salmonella typhimurium genes. Unexpectedly we found by mass spectrometry that these enzymes had been modified posttranslationally in vivo by a mechanism-based "suicide" inactivation. A large percentage of the alpha subunit of each enzyme had been modified in vivo to give peaks with masses m/z = 57 +/- 1 and m/z = 75 +/- 1 daltons higher than the parent peak. AdoMetDC activity decreased markedly during overexpression concurrently with the increase of the additional peaks for the alpha subunit. Sequencing of a tryptic fragment by tandem mass spectrometry showed that Cys-140 was modified with a +75 +/- 1 adduct, which is probably derived from the reaction product. Comparable modification of the alpha subunit was also observed in in vitro experiments after incubation with the substrate or with the reaction product, which is consistent with the in vitro alkylation of E. coli AdoMetDC reported by Diaz and Anton [Diaz, E. & Anton, D. L. (1991) Biochemistry 30, 4078-4081].

Expedition 54 Press Conference

NASA Image and Video Library

2017-12-16

Expedition 54 backup crew member Sergey Prokopev is seen in quarantine, behind glass, during a press conference, Saturday, Dec. 16, 2017 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Expedition 54 prime crew members Soyuz Commander Anton Shkaplerov of Roscosmos, flight engineer Scott Tingle of NASA, and flight engineer Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) are scheduled to launch to the International Space Station aboard the Soyuz spacecraft from the Baikonur Cosmodrome on December 17. Photo Credit: (NASA/Joel Kowsky)

Expedition 54 Press Conference

NASA Image and Video Library

2017-12-16

Expedition 54 prime crew members flight engineer Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA), left, Soyuz Commander Anton Shkaplerov of Roscosmos, center, and flight engineer Scott Tingle of NASA, left, are seen in quarantine, behind glass, during a press conference, Saturday, Dec. 16, 2017 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Kanai, Shkaplerov, and Tingle are scheduled to launch to the International Space Station aboard the Soyuz spacecraft from the Baikonur Cosmodrome on December 17. Photo Credit: (NASA/Joel Kowsky)

16. 'EXCELLENT NEW PARADE GROUND BEST SINCE POST ESTABLISHED. STARTED ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

16. 'EXCELLENT NEW PARADE GROUND BEST SINCE POST ESTABLISHED. STARTED BY COL. RALPH PARKER, FINISHED BY COL. TROUPE MILLER, PRESIDIO OF MONTEREY CALIFORNIA.' No date, probably ca. 1936. No signature, photographer probably Anton C. Heidrick. This panoramic view looks east over Soldier Field to the Bay, from the cannons at the west end. Original hand tinted silver gelatin print measures 90.4 cm by 20.2 cm, flush mounted on mat board. - Presidio of Monterey, Soldier Field, Monterey, Monterey County, CA

jsc2014e092329

NASA Image and Video Library

2014-11-06

4108: At the Kremlin Wall in Red Square in Moscow, Expedition 42/43 crewmember Samantha Cristoforetti of the European Space Agency lays flowers Nov. 6 at the site where Russian space icons are interred. Cristoforetti, Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) and Terry Virts of NASA will launch Nov. 24, Kazakh time from the Baikonur Cosmodrome in Kazakhstan on their Soyuz TMA-15M spacecraft for a 5 ½ month mission on the International Space Station. NASA/Stephanie Stoll

jsc2014e093279

NASA Image and Video Library

2014-11-18

6103: At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 42/43 crewmember Samantha Cristoforetti of the European Space Agency tests her vestibular system on a tilt table Nov. 18 as part of pre-launch training. Cristoforetti, Terry Virts of NASA and Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) will launch Nov. 24, Kazakh time, from the Baikonur Cosmodrome in the Soyuz TMA-15M spacecraft for a 5 ½ month mission on the International Space Station. NASA/Sergei Fyodorov

Evapotranspiration-based Irrigation Scheduling for Container-grown Viburnum odoratissium (L.) Ker Gawl

USDA-ARS?s Scientific Manuscript database

The capacity for evapotranspiration (ET)-based irrigation scheduling to reduce runoff volume and nutrient leaching was tested in Fall 2004 and Spring 2005. Runoff (container leachate plus unintercepted irrigation and precipitation) was collected continuously for 17 weeks during production of sweet ...

Software Reviews: "Pow! Zap! Ker-plunk! The Comic Book Maker" (Pelican Software).

ERIC Educational Resources Information Center

Porter, Bernajean

1990-01-01

Reviews the newest addition to Pelican's Creative Writing Series of instructional software, which uses the comic book format to provide a unique writing environment for satire, symbolism, sequencing, and combining text and graphics to communicate ideas. (SR)

Materials Data on KEr(PO3)4 (SG:4) by Materials Project

DOE Data Explorer

Kristin Persson

2016-02-04

Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

Investigation of electronically excited indole relaxation dynamics via photoionization and fragmentation pump-probe spectroscopy.

PubMed

Godfrey, T J; Yu, Hui; Ullrich, Susanne

2014-07-28

The studies herein investigate the involvement of the low-lying (1)La and (1)Lb states with (1)ππ(*) character and the (1)πσ(*) state in the deactivation process of indole following photoexcitation at 201 nm. Three gas-phase, pump-probe spectroscopic techniques are employed: (1) Time-resolved photoelectron spectroscopy (TR-PES), (2) hydrogen atom (H-atom) time-resolved kinetic energy release (TR-KER), and (3) time-resolved ion yield (TR-IY). Each technique provides complementary information specific to the photophysical processes in the indole molecule. In conjunction, a thorough examination of the electronically excited states in the relaxation process, with particular focus on the involvement of the (1)πσ(*) state, is afforded. Through an extensive analysis of the TR-PES data presented here, it is deduced that the initial excitation of the (1)Bb state decays to the (1)La state on a timescale beyond the resolution of the current experimental setup. Relaxation proceeds on the (1)La state with an ultrafast decay constant (<100 femtoseconds (fs)) to the lower-lying (1)Lb state, which is found to possess a relatively long lifetime of 23 ± 5 picoseconds (ps) before regressing to the ground state. These studies also manifest an additional component with a relaxation time of 405 ± 76 fs, which is correlated with activity along the (1)πσ(*) state. TR-KER and TR-IY experiments, both specifically probing (1)πσ(*) dynamics, exhibit similar decay constants, further validating these observations.

iss054e027048

NASA Image and Video Library

2018-02-02

iss054e027048 (Feb. 2, 2018) --- A Russian spacewalker is seen in an Orlan spacesuit with blue stripes (center image) working outside the Zvezda service module during the longest spacewalk in Russian space program history on Feb. 2, 2018. Cosmonauts Alexander Misurkin and Anton Shkaplerov wrapped up the eight hour and 13 minute spacewalk after installing a new electronics and telemetry box for the high gain antenna on Zvezda. The new gear will enhance communications between Russian flight controllers and the Russian modules.

jsc2017e137337 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmember Scott Tingle of NASA plays a game of chess Dec. 11 during a break in his pre-launch training. Tingle, Norishige Kanai of the Japan Aerospace E

NASA Image and Video Library

2017-12-11

jsc2017e137337 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmember Scott Tingle of NASA plays a game of chess Dec. 11 during a break in his pre-launch training. Tingle, Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) and Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) will launch Dec. 17 on the Soyuz MS-07 spacecraft from the Baikonur Cosmodrome for a five month mission on the International Space Station...Andrey Shelepin / Gagarin Cosmonaut Training Center.

Chemical Analysis of the Dyes Used in Navy Green and Yellow Colored Smokes .

DTIC Science & Technology

1986-01-31

RD-RI69 478 CHEMICAL ANALYSIS OF THE DYES USED IN NAVY OREEN AND 11 YELLOW COLORED SNOKES(U) NAVAL WEAPONS SUP POR T CENTER CRANE IN APPLIED SCIENCES...NWSC/CR/RDTR-271 00 CHEMICAL ANALYSIS OF THE DYES USED IN NAVY GREEN AND YELLOW COLORED SMOKES Anton Chin Naval Weapons Support Center Applied Sciences...62765 SF65-559 559-691 20392 TITLE (Iint/ude Sec uritE C/assitication) CHEMICAL ANALYSIS OF THE DYES USED IN NAVY GREEN AND YELLOW COLORED SMOKES 1.1

Space Station Cosmonauts Walk in Space to Upgrade Communications Hardware

NASA Image and Video Library

2018-02-02

Aboard the International Space Station, Expedition 54 Flight Engineers Alexander Misurkin and Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) conducted a spacewalk outside the Pirs docking compartment Feb. 2 to install a new high-gain communications antenna on the aft end of the Zvezda Service Module and retrieve science experiment packages from the hull of the module. It was the 208th spacewalk in support of space station assembly and maintenance, the fourth in Misurkin’s career and the second for Shkaplerov.

jsc2014e092317

NASA Image and Video Library

2014-11-06

3851: At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 42/43 crewmember Samantha Cristoforetti of the European Space Agency (right) signs a ceremonial book Nov. 6 as her crewmates, Terry Virts of NASA (left) and Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos, center) look on. Virts, Cristoforetti and Shkaplerov will launch Nov. 24, Kazakh time from the Baikonur Cosmodrome in Kazakhstan on their Soyuz TMA-15M spacecraft for a 5 ½ month mission on the International Space Station. NASA/Stephanie Stoll

The speEspeD operon of Escherichia coli. Formation and processing of a proenzyme form of S-adenosylmethionine decarboxylase.

PubMed

Tabor, C W; Tabor, H

1987-11-25

We have previously shown that the gene (speD) for S-adenosylmethionine decarboxylase is part of an operon that also contains the gene (speE) for spermidine synthase (Tabor, C. W., Tabor, H., and Xie, Q.-W. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 6040-6044). We have now determined the nucleotide sequence of this operon and have found that speD codes for a polypeptide of Mr = 30,400, which is considerably greater than the subunit size of the purified enzyme. Our studies show that S-adenosylmethionine decarboxylase is first formed as a Mr = 30,400 polypeptide and that this proenzyme is then cleaved at the Lys111-Ser112 peptide bond to form a Mr = 12,400 subunit and a Mr = 18,000 subunit. The latter subunit contains the pyruvoyl moiety that we previously showed is required for enzymatic activity. Both subunits are present in the purified enzyme. These conclusions are based on (i) pulse-chase experiments with a strain containing a speD+ plasmid which showed a precursor-product relationship between the proenzyme and the enzyme subunits, (ii) the amino acid sequence of the proenzyme form of S-adenosylmethionine decarboxylase (derived from the nucleotide sequence of the speD gene), and (iii) comparison of this sequence of the proenzyme with the N-terminal amino acid sequences of the two subunits of the purified enzyme reported by Anton and Kutny (Anton, D. L., and Kutny, R. (1987) J. Biol. Chem. 262, 2817-2822).

In vivo mechanism-based inactivation of S-adenosylmethionine decarboxylases from Escherichia coli, Salmonella typhimurium, and Saccharomyces cerevisiae

PubMed Central

Li, Yong-Fu; Hess, Sonja; Pannell, Lewis K.; Tabor, Celia White; Tabor, Herbert

2001-01-01

S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme in the biosynthesis of spermidine and spermine, is first synthesized as a proenzyme, which is cleaved posttranslationally to form α and β subunits. The α subunit contains a covalently bound pyruvoyl group derived from serine that is essential for activity. With the use of an Escherichia coli overexpression system, we have purified AdoMetDCs encoded by the E. coli, Saccharomyces cerevisiae, and Salmonella typhimurium genes. Unexpectedly we found by mass spectrometry that these enzymes had been modified posttranslationally in vivo by a mechanism-based “suicide” inactivation. A large percentage of the α subunit of each enzyme had been modified in vivo to give peaks with masses m/z = 57 ± 1 and m/z = 75 ± 1 daltons higher than the parent peak. AdoMetDC activity decreased markedly during overexpression concurrently with the increase of the additional peaks for the α subunit. Sequencing of a tryptic fragment by tandem mass spectrometry showed that Cys-140 was modified with a +75 ± 1 adduct, which is probably derived from the reaction product. Comparable modification of the α subunit was also observed in in vitro experiments after incubation with the substrate or with the reaction product, which is consistent with the in vitro alkylation of E. coli AdoMetDC reported by Diaz and Anton [Diaz, E. & Anton, D. L. (1991) Biochemistry 30, 4078–4081]. PMID:11526206

Earth observation taken by the Expedition 43 crew

NASA Image and Video Library

2015-04-01

ISS043E080914 (04/01/2015) --- This Earth view from the International Space Station Apr. 1, 2015 (bottom left corner) is Soyuz TMA-15M which carried NASA astronaut Terry Virts, ESA (European Space Agency) astronaut Samantha Cristoforetti and Russian cosmonaut Anton Shkaplerov to the ISS back in No. 2014 and will remain until May 2015. The further one (top left corner) is Progress 57 a Russian supply spaceship which launched and docked in October last year and will undock at the end of April to return to Earth.

The Perseids Aug 11-12, 1996 in Bulgaria

NASA Astrophysics Data System (ADS)

Bojurova, E.; Trukchev, I.

As every year Astroclub "Canopus" organized an extended Perseid observing campaign. Members of the club took part in expedition to Avren village near Varna, at the National Astronomical Observatory (Rojen) and at the National Yought Astronomical Camp in Belite Brezi (South Bulgaria). Here we present some results derived on the basis of data obtained by Biliana Ognianova, Diana Tisheva, Diliana Antonova, Eva Bojurova, Elena Surbinska, Irena Stavreva, Katia Koleva, Lilia Porojanova, Anton Antonov, Denis Mechmedov, Doichin Docinski, Galin Genchev, Ivan Trukhchev, Valentin Velkov. More than 2000 Perseids were recorded. Some other showers were also observed.

Soyuz-MS-07_Farewell-Hatch-Closure_June-3-2018_660949

NASA Image and Video Library

2018-06-04

Expedition 55 Crew Lands Safely in Kazakhstan to Complete Almost Six Months In Space------ Expedition 55 Commander Anton Shkaplerov of Roscosmos and Flight Engineers Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) landed safely near the town of Dzhezkazgan, Kazakhstan June 3 after bidding farewell to their colleagues on the complex and undocking their Soyuz MS-07 spacecraft from the Rassvet Module on the International Space Station. The trio spent almost six months in space conducting research and operational work in support of the station.

Change of Command

NASA Image and Video Library

2011-11-20

ISS029-E-043148 (20 Nov. 2011) --- Expedition 28/29 and Expedition 29/30 crew members pose for a group portrait in the International Space Station?s Kibo laboratory following the ceremony of Changing-of-Command from Expedition 29 to Expedition 30. Pictured from the left are Russian cosmonaut Anatoly Ivanishin, Expedition 30 flight engineer; NASA astronaut Dan Burbank, Expedition 30 commander; Anton Shkaplerov, Expedition 30 flight engineer; Russian cosmonaut Sergei Volkov, Expedition 29 flight engineer; NASA astronaut Mike Fossum, Expedition 29 commander; and Japan Aerospace Exploration Agency astronaut Satoshi Furukawa, Expedition 29 flight engineer.

Change of Command

NASA Image and Video Library

2011-11-20

ISS029-E-043144 (20 Nov. 2011) --- Expedition 28/29 and Expedition 29/30 crew members pose for a group portrait in the International Space Station?s Kibo laboratory following the ceremony of Changing-of-Command from Expedition 29 to Expedition 30. Pictured from the left are Russian cosmonaut Anatoly Ivanishin, Expedition 30 flight engineer; NASA astronaut Dan Burbank, Expedition 30 commander; Anton Shkaplerov, Expedition 30 flight engineer; Russian cosmonaut Sergei Volkov, Expedition 29 flight engineer; NASA astronaut Mike Fossum, Expedition 29 commander; and Japan Aerospace Exploration Agency astronaut Satoshi Furukawa, Expedition 29 flight engineer.

Dispersion Strengthening of High Temperature Niobium Alloys

DTIC Science & Technology

1988-05-31

Fig. 2 for the alloys containing ZrC and Ta6 Si3 respectively. The former shows classical age .hardening response with hardening followed by softening...tILE COP) ION STRENGTH’ENING OF HIGH TEMATURE NIOBIUM ALLOYS Prepared by D.L. Anton 00 D.B. Snow In) A.F. Giamei ANNUAL REPORT Contract F49620486-C...Center / ni .’ - k- ADDRESS (Ciy, State, and ZIP Code) 7b ADDRESS (City, State, and ZIP Code) East Hartford, CT 06108 7-Jc\\ 4 0 _ .F3 A.C 8a. NAME OF

JAXA PAO VIP Event 3318_624493_hires

NASA Image and Video Library

2018-03-05

SPACE STATION CREW DISCUSSES LIFE IN SPACE WITH JAPANESE OFFICIALS --------------------------------------------------------- Aboard the International Space Station, Expedition 55 Commander Anton Shkaplerov of Roscosmos and Flight Engineers Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) discussed life and research on the orbital laboratory during an in-flight question and answer session March 3 with Japanese space officials and policy ministers attending the International Space Explorers Forum (ISEF-2) in Tokyo. The trio is in the midst of a five-and-a-half-month mission on the station.

Expedition 30 Landing

NASA Image and Video Library

2012-04-27

NASA and GCTC (Gagarin Cosmonaut Training Center) crew support personnel enter the inflatable medical tent in which Expedition 30 Commander Dan Burbank, and flight engineers Anton Shkaplerov and Anatoly Ivanishin are being checked out shortly after their Soyuz TMA-22 capsule landed out side the town of Arkalyk, Kazakhstan, Friday, April 27, 2012. Burbank, and Russian Cosmonauts Shkaplerov and Ivanishin are returning from more than five months onboard the International Space Station where they served as members of the Expedition 29 and 30 crews. Photo Credit: (NASA/Carla Cioffi)

Accuracy Assessment for the Auxillary Tracking System

DTIC Science & Technology

1991-09-01

Auxiliary Tracking System (ATS), paper prepared for evaluation of ATS design review, 28 June, 1990. Anton , H., and Rorres, C., Elementary Linear Algebra with...are linearized around the trial value (XT6, YT,, Zro), shown in Equation 3.16, where 10 means evaluated at point "o". The OR1aI * YaT- I T.) ZR (ZT...3.16) partial derivatives are listed in Equations 3.17 through 3.19. 8XR.[ o 7.-OR1 [ .XT-XL (3.17) aOR., ZTo-Z 1 (3.19) aZTIo R. The linearized

jsc2017e136060 - On a snowy night at Red Square in Moscow, Expedition 54-55 crewmember Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) lays flowers at the Kremlin Wall where Russian space icons are interred in traditional pre-launch cerem

NASA Image and Video Library

2017-11-30

jsc2017e136060 - On a snowy night at Red Square in Moscow, Expedition 54-55 crewmember Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) lays flowers at the Kremlin Wall where Russian space icons are interred in traditional pre-launch ceremonies Nov. 30. Kanai, Scott Tingle of NASA and Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) will launch from the Baikonur Cosmodrome in Kazakhstan on the Soyuz MS-07 spacecraft Dec. 17 for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

Applied Mathematical Modules for Use in a Linear Algebra Service Course

DTIC Science & Technology

1990-05-01

H . (1977). Elements of ohysical chemistry. Reading, MA: Addison-Wesley. Rorres , C . & Anton , H . (1984). Applications...k t)r+ v𔃽 A142"+ c -- + C Vt +1 t+ C c tKc cos t 2= 113 123 313 32-3 51 2 V - cu-14sin r t) 232 _E _ VL3 h 3kx3 Cl t + c1 _3 t c + 3 =11-3 12 3 31 6... H " O H H H o 0 0 H H H H H H Ao, //o\\ H HH H

jsc2017e136049 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 prime crewmember Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) listens to a reporter’s question during a crew news conference Nov. 30. Ka

NASA Image and Video Library

2017-11-30

jsc2017e136049 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 prime crewmember Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) listens to a reporter’s question during a crew news conference Nov. 30. Kanai, Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) and Scott Tingle of NASA will launch Dec. 17 on the Soyuz MS-07 spacecraft from the Baikonur Cosmodrome in Kazakhstan for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

jsc2017e135207 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 prime crewmember Norishige Kanai of the Japan Aerospace Exploration Space Agency (JAXA) listens to a reporters’ question Nov. 29 as part of the crew’s fin

NASA Image and Video Library

2017-11-29

jsc2017e135207 - At the Gagarin Cosmonaut Training Center in Star City, Russia, Expedition 54-55 prime crewmember Norishige Kanai of the Japan Aerospace Exploration Space Agency (JAXA) listens to a reporters’ question Nov. 29 as part of the crew’s final qualification exam activities. Kanai, Scott Tingle of NASA and Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) will launch Dec. 17 on the Soyuz MS-07 spacecraft from the Baikonur Cosmodrome in Kazakhstan for a five-month mission on the International Space Station...NASA/Elizabeth Weissinger.

jsc2017e137339 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmember Scott Tingle of NASA tests his vestibular skills on a rotating chair Dec. 11 as part of his pre-launch training. Tingle, Norishige Kanai of th

NASA Image and Video Library

2017-12-11

jsc2017e137339 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmember Scott Tingle of NASA tests his vestibular skills on a rotating chair Dec. 11 as part of his pre-launch training. Tingle, Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) and Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) will launch Dec. 17 on the Soyuz MS-07 spacecraft from the Baikonur Cosmodrome for a five month mission on the International Space Station...Andrey Shelepin / Gagarin Cosmonaut Training Center.

jsc2017e137341 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmembers Scott Tingle of NASA (left) and Norishige Kanai of the Japan Aerospace Exploration Agency (right) test their vestibular skills on tilt tables

NASA Image and Video Library

2017-12-11

jsc2017e137341 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmembers Scott Tingle of NASA (left) and Norishige Kanai of the Japan Aerospace Exploration Agency (right) test their vestibular skills on tilt tables Dec. 11 as part of their pre-launch training. Along with Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos), they will launch Dec. 17 on the Soyuz MS-07 spacecraft from the Baikonur Cosmodrome for a five month mission on the International Space Station...Andrey Shelepin / Gagarin Cosmonaut Training Center.

ATCA-based ATLAS FTK input interface system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Okumura, Yasuyuki; Liu, Tiehui Ted; Olsen, Jamieson

The first stage of the ATLAS Fast TracKer (FTK) is an ATCA-based input interface system, where hits from the entire silicon tracker are clustered and organized into overlapping eta-phi trigger towers before being sent to the tracking engines. First, FTK Input Mezzanine cards receive hit data and perform clustering to reduce data volume. Then, the ATCA-based Data Formatter system will organize the trigger tower data, sharing data among boards over full mesh backplanes and optic fibers. The board and system level design concepts and implementation details, as well as the operation experiences from the FTK full-chain testing, will be presented.

Effectiveness of Incendiary Ammunition Against Aircraft Fuel Tanks

DTIC Science & Technology

1948-10-05

r ker~e::le fillei ranks, Fer lhese figures, aU funcUoning t>Srf:Jraticne were c.;:mstdered for projectiles :m- pcting en previot :.Sly ur.Car.::aged... weight in u:-.fts of lCOJ grair.s wf"’ filler weight in units C: 100 grains As a typical example 3f the use of the formula, ccmsider the T36E2" CaL...0,60 rouaC str!k!ng at 2100 f:.jsec. ?:J.e p:-cjectile weight is l: 50 grair.s and t~e fUler weight is 92 grains. Tte !::•:-mula yidds "𔃺.80 The

Serologic evidence of human Rickettsia infection found in three locations in Panamá.

PubMed

Bermúdez, Sergio E; Lyons, Cirilo R; García, Gleydis G; Zaldíva, Yamitzel L; Gabster, Amanda; Arteaga, Griselda B

2013-09-01

Since the middle of last century, cases of rickettsiosis have been found in Panamá when outbreaks of murine typhus and spotted fever were reported. Since then, little information exists about its prevalence in this country, since it is most often is misdiagnosed as another disease. The aim of this paper is to demonstrate the presence of Rickettsia infections in humans in three locations in Panamá. These locations are agricultural areas, near forested areas or those who work in zoo. Three locations where chosen for this study: Tortí, El Valle de Antón and workers in the Summit Municipal Park in Panamá City. All volunteers signed an informed consent and answered a questionnaire. The samples were analyzed for the detection of rickettsial spotted fever and typhus group by the indirect immunofluorescence (using commercial kits) and antigens of Rickettsia rickettsii and R. amblyommii. Blood samples were taken from 97 volunteers in Tortí (25), El Valle de Anton (37) and Summit Municipal Park (35). Of these, a total of 38 (39%) samples reacted to one of the two methods: eight (32%) in Tortí, 18 (48%) in El valle and 12 (34%) in Summit Municipal Park. The results show a high prevalence of antibodies to Rickettsia belonging to the spotted fever group in each of the three study areas, in addition to presenting evidence of the typhus group Rickettsia in El Valle de Anton. These areas could be considered endemic for rickettsiosis as there are conditions for maintaining them.

Impact of craving on alcohol relapse during, and 12 months following, outpatient treatment.

PubMed

Bottlender, Miriam; Soyka, Michael

2004-01-01

This study investigated the relationship between craving in abstinent alcohol-dependent patients measured by the Obsessive Compulsive Craving Scale (OCDS) (Anton et al., 1995) and relapse during and after completion of an intensive outpatient treatment programme. In a prospective study, participants were interviewed at entry to, and end of, an outpatient treatment programme, and 12 months after the end of the programme. To measuring craving the OCDS total score by Anton et al. (1995) and the three-factor model by Kranzler et al. (1999) were used. OCDS was administered at the beginning of treatment (when all patients were abstinent), and at the end of treatment in those who were abstinent and had completed the programme. Of 103 alcohol-dependent patients, 74 completed the treatment programme and at follow-up after 12 months 97% of these patients were personally re-interviewed. Thirty-two patients (31%) relapsed during the treatment phase. They had significantly higher craving measured by the total OCDS score and a significantly higher score on the subscales 'obsessions' and 'drinking control and consequences' compared to abstinent patients. Of the 74 patients who completed the programme 16% had a major relapse in the next 12 months. Major relapse was predicted by the total OCDS score and the subscale 'obsessions'. OCDS total score predicts relapse in outpatient treatment. Treatment and aftercare of patients with high craving should be intensified. In our study design, the subscales of the three-factor model by Kranzler et al. (1999) provided only little information gain compared to the OCDS total score.

jsc2017e137338 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmember Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) tries his hand at a game of billiards Dec. 11 during a break in pre-launch tr

NASA Image and Video Library

2017-12-11

jsc2017e137338 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmember Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) tries his hand at a game of billiards Dec. 11 during a break in pre-launch training while backup crewmember Jeanette Epps of NASA looks on. Kanai, Scott Tingle of NASA and Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) will launch Dec. 17 on the Soyuz MS-07 spacecraft from the Baikonur Cosmodrome for a five month mission on the International Space Station...Andrey Shelepin / Gagarin Cosmonaut Training Center.

jsc2011e027535

NASA Image and Video Library

2011-03-21

At the Baikonur Cosmodrome in Kazakhstan, Expedition 27 Flight Engineer Ron Garan of NASA (left), Soyuz Commander Alexander Samokutyaev (center) and Flight Engineer Andrey Borisenko (right) are greeted upon their arrival March 21, 2011 by RSC-Energia Vice-President Nikolai Zelenchikov after their flight to the launch site from Star City, Russia. The trio, and their backups, Anatoly Ivanishin, Anton Shkaplerov and Dan Burbank are in the final weeks of training for their launch April 5 (April 4, U.S. time) on the Soyuz TMA-21 spacecraft to the International Space Station. Credit: NASA/Victor Zelentsov

Burbank and Shkaplerov review crew procedures

NASA Image and Video Library

2012-03-24

ISS030-E-171107 (24 March 2012) --- NASA astronaut Dan Burbank (left), Expedition 30 commander; and Russian cosmonaut Anton Shkaplerov, flight engineer, wearing communication headsets, review crew procedures in the Zvezda Service Module of the International Space Station in preparation of moving to the appropriate Soyuz vehicles, due to the possibility that space debris could pass close to the station. Burbank, Shkaplerov and Ivanishin sheltered in the Soyuz TMA-22 spacecraft attached to the Poisk Mini-Research Module 2 (MRM2) while Kononenko, Kuipers and Pettit took to the Soyuz TMA-03M docked to the Rassvet Mini-Research Module 1 (MRM-1).

Change of Command

NASA Image and Video Library

2011-11-20

ISS029-E-043136 (20 Nov. 2011) --- Expedition 28/29 and Expedition 29/30 crew members pose for a group portrait in the International Space Station?s Kibo laboratory following the ceremony of Changing-of-Command from Expedition 29 to Expedition 30. Pictured on the front row are NASA astronauts Dan Burbank (left), Expedition 30 commander; and Mike Fossum, Expedition 29 commander. Pictured from the left (back row) are Russian cosmonauts Anatoly Ivanishin, and Anton Shkaplerov, both Expedition 30 flight engineers; and Sergei Volkov, Expedition 29 flight engineer; along with Japan Aerospace Exploration Agency astronaut Satoshi Furukawa, Expedition 29 flight engineer.

Change of Command

NASA Image and Video Library

2011-11-20

ISS029-E-043133 (20 Nov. 2011) --- Expedition 28/29 and Expedition 29/30 crew members pose for a group portrait in the International Space Station?s Kibo laboratory following the ceremony of Changing-of-Command from Expedition 29 to Expedition 30. Pictured on the front row are NASA astronauts Dan Burbank (left), Expedition 30 commander; and Mike Fossum, Expedition 29 commander. Pictured from the left (back row) are Russian cosmonauts Anatoly Ivanishin, and Anton Shkaplerov, both Expedition 30 flight engineers; and Sergei Volkov, Expedition 29 flight engineer; along with Japan Aerospace Exploration Agency astronaut Satoshi Furukawa, Expedition 29 flight engineer.

Pigment characterization of important golden age panel paintings of the 17th century

NASA Astrophysics Data System (ADS)

Pięta, Ewa; Proniewicz, Edyta; Szmelter-Fausek, Bożena; Olszewska-Świetlik, Justyna; Proniewicz, Leonard M.

2015-02-01

Samples were obtained from two world-famous 17th century panel paintings of the Gdańsk school of panting: 'Seven Acts of Charity' (1607, in St. Mary's Church in Gdańsk, Poland) by Anton Möller and 'Angelic Concert' (1611, in Diocesan Museum in Pelplin, Poland) by Hermann Han. Micro-Raman spectroscopy (MRS), optical microscopy (OM), and X-ray fluorescence (XRF) spectroscopy studies of the samples were performed to characterize the pigments present in the individual painting layers (a rich palette of white, black, blue, red, and yellow pigments) and the pictorial techniques used by the artists.

Expedition 54 Soyuz Docking

NASA Image and Video Library

2017-12-19

NASA International Space Station Program Manager Kirk Shireman speaks with the Expedition 54 crew from the Moscow Mission Control Center in Korolev, Russia a few hours after the Soyuz MS-07 docked to the International Space Station on Tuesday, Dec. 19, 2017. Hatches were opened at 5:55 a.m. EST and Anton Shkaplerov of Roscosmos, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) joined Expedition 54 Commander Alexander Misurkin of Roscosmos and crewmates Mark Vande Hei and Joe Acaba of NASA aboard the orbiting laboratory. Photo Credit: (NASA/Joel Kowsky)

Expedition 54 Soyuz Docking

NASA Image and Video Library

2017-12-19

Japan Aerospace Exploration Agency (JAXA) International Space Station Program Manager Koichi Wakata speaks with the Expedition 54 crew from the Moscow Mission Control Center in Korolev, Russia a few hours after the Soyuz MS-07 docked to the International Space Station on Tuesday, Dec. 19, 2017. Hatches were opened at 5:55 a.m. EST and Anton Shkaplerov of Roscosmos, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) joined Expedition 54 Commander Alexander Misurkin of Roscosmos and crewmates Mark Vande Hei and Joe Acaba of NASA aboard the orbiting laboratory. Photo Credit: (NASA/Joel Kowsky)

Analysis and Evaluation of Project EVERGREEN Data

DTIC Science & Technology

1991-09-01

1 9 9c9" 9 9 9 91?t- VI vi rl i v AH AR AA R a- 6 4 h 1" t - 10 i h t -: .4 .a: : t : 3 t : ta at ~ ~’~ M ~4C ~ C0.~b ~ ~ qO ~ Cm @ el 0. z ~M C q f... Anton , Howard and Rorres , Chris, Elementary Linear Algebra with AyDlications, John Wiley and Sons, New York, 1987. 2. Binnall, Eugene P., EVERGREEN... C . ANALYSIS OF INDIVIDUAL WAVEFORMS.........52 1. Directory 5-1-90 . . . . . .. .. .. .. ... 58 a. Waveform NTSO4BO1.WFM............58 b. Waveform

Creativity and mood disorders: The enigmatic case of Isaak Il'ich Levitan (1860-1900).

PubMed

Lerner, Vladimir; Margolin, Jacob; Witztum, Eliezer

2017-05-01

Isaak Levitan (1860-1900) was one of Russia's most influential landscape artists. He lived a very short life, only 40 years, but left more than 1000 paintings. He suffered from mood fluctuations, and died as a result of serious heart disease. After an introduction related to the issue of creativity and mental disorders, a short biography of Levitan's life is outlined, followed by some examples of his mood and behavior. A section on the mood's reflection in Levitan's professional work is followed by a description of his romantic loves and disappointments and his relationship with his contemporary Russian, the writer Anton Chekhov.

Multiple Restrictions of Human Immunodeficiency Virus Type 1 in Feline Cells▿

PubMed Central

Münk, Carsten; Zielonka, Jörg; Constabel, Hannelore; Kloke, Björn-Philipp; Rengstl, Benjamin; Battenberg, Marion; Bonci, Francesca; Pistello, Mauro; Löchelt, Martin; Cichutek, Klaus

2007-01-01

The productive replication of human immunodeficiency virus type 1 (HIV-1) occurs exclusively in defined cells of human or chimpanzee origin, explaining why heterologous animal models for HIV replication, pathogenesis, vaccination, and therapy are not available. This lack of an animal model for HIV-1 studies prompted us to examine the susceptibility of feline cells in order to evaluate the cat (Felis catus) as an animal model for studying HIV-1. Here, we report that feline cell lines harbor multiple restrictions with respect to HIV-1 replication. The feline CD4 receptor does not permit virus infection. Feline T-cell lines MYA-1 and FeT-1C showed postentry restrictions resulting in low HIV-1 luciferase reporter activity and low expression of viral Gag-Pol proteins when pseudotyped vectors were used. Feline fibroblastic CrFK and KE-R cells, expressing human CD4 and CCR5, were very permissive for viral entry and HIV-long terminal repeat-driven expression but failed to support spreading infection. KE-R cells displayed a profound block with respect to release of HIV-1 particles. In contrast, CrFK cells allowed very efficient particle production; however, the CrFK cell-derived HIV-1 particles had low specific infectivity. We subsequently identified feline apolipoprotein B-editing catalytic polypeptide 3 (feAPOBEC3) proteins as active inhibitors of HIV-1 particle infectivity. CrFK cells express at least three different APOBEC3s: APOBEC3C, APOBEC3H, and APOBEC3CH. While the feAPOBEC3C did not significantly inhibit HIV-1, the feAPOBEC3H and feAPOBEC3CH induced G to A hypermutations of the viral cDNA and reduced the infectivity ∼10- to ∼40-fold. PMID:17459941

Ionization and dissociation of molecular ion beams by intense ultrafast laser pulses

NASA Astrophysics Data System (ADS)

Ben-Itzhak, Itzik

2007-06-01

Laser-induced dissociation and ionization of a diatomic molecular-ion beam were simultaneously measured using coincidence 3D momentum imaging, with direct separation of the two processes even where the fragment kinetic energy is the same for both processes. We mainly focus on the fundamental H2^+ molecule in 7-135 fs laser pulses having 10^13-10^15 W/cm^2 peak intensity. At high intensities the kinetic energy release (KER) distribution following ionization of H2^+ was measured to be broad and structureless. Its centroid shifts toward higher energies as the laser intensity is increased indicating that ionization shifts to smaller internuclear distances. In contrast, a surprising structure is observed near the ionization threshold, which we call above threshold Coulomb explosion (ATCE) [1]. The angular distributions of the two H^+ fragments are strongly peaked along the laser polarization, and the angular distribution is described well by [cos^2θ]^n, where n is the number of photons predicted by our ATCE model [1]. Our data indicates that n varies with the laser wavelength as predicted by the model. The KER and angular distributions of H2^+ dissociation change dramatically with decreasing pulse width over the 7-135 fs range in contrast to the reported trend for longer pulses. Others contributing to this work: A.M. Sayler, P.Q. Wang, J. McKenna, B. Gaire, Nora G. Johnson, E. Parke, K.D. Carnes, and B.D. Esry. Thank are due to Professor Zenghu Chang for providing the intense laser beams and Dr. Charles Fehrenbach for his help with the ion beams. [1] B.D. Esry, A.M. Sayler, P.Q. Wang, K.D. Carnes, and I. Ben-Itzhak, Phys. Rev. Lett. 97, 013003 (2006).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Godfrey, T. J.; Yu, Hui; Ullrich, Susanne, E-mail: ullrich@physast.uga.edu

The studies herein investigate the involvement of the low-lying {sup 1}L{sub a} and {sup 1}L{sub b} states with {sup 1}ππ{sup *} character and the {sup 1}πσ{sup *} state in the deactivation process of indole following photoexcitation at 201 nm. Three gas-phase, pump-probe spectroscopic techniques are employed: (1) Time-resolved photoelectron spectroscopy (TR-PES), (2) hydrogen atom (H-atom) time-resolved kinetic energy release (TR-KER), and (3) time-resolved ion yield (TR-IY). Each technique provides complementary information specific to the photophysical processes in the indole molecule. In conjunction, a thorough examination of the electronically excited states in the relaxation process, with particular focus on the involvement ofmore » the {sup 1}πσ{sup *} state, is afforded. Through an extensive analysis of the TR-PES data presented here, it is deduced that the initial excitation of the {sup 1}B{sub b} state decays to the {sup 1}L{sub a} state on a timescale beyond the resolution of the current experimental setup. Relaxation proceeds on the {sup 1}L{sub a} state with an ultrafast decay constant (<100 femtoseconds (fs)) to the lower-lying {sup 1}L{sub b} state, which is found to possess a relatively long lifetime of 23 ± 5 picoseconds (ps) before regressing to the ground state. These studies also manifest an additional component with a relaxation time of 405 ± 76 fs, which is correlated with activity along the {sup 1}πσ{sup *} state. TR-KER and TR-IY experiments, both specifically probing {sup 1}πσ{sup *} dynamics, exhibit similar decay constants, further validating these observations.« less

Discriminating leptonic Yukawa interactions with doubly charged scalar at the ILC

NASA Astrophysics Data System (ADS)

Nomura, Takaaki; Okada, Hiroshi; Yokoya, Hiroshi

2018-04-01

We explore discrimination of two types of leptonic Yukawa interactions associated with Higgs triplet, LbarLc ΔLL, and with SU (2) singlet doubly charged scalar, ebarRc k++eR. These interactions can be distinguished by measuring the effects of doubly charged scalar boson exchange in the e+e- →ℓ+ℓ- processes at polarized electron-positron colliders. We study a forward-backward asymmetry of scattering angular distribution to estimate the sensitivity for these effects at the ILC. In addition, we investigate prospects of upper bounds on the Yukawa couplings by combining the constraints of lepton flavor violation processes and the e+e- →ℓ+ℓ- processes at the LEP and the ILC.

Convergence and reproducibility in molecular dynamics simulations of the DNA duplex d(GCACGAACGAACGAACGC)

PubMed Central

Galindo-Murillo, Rodrigo; Roe, Daniel R.; Cheatham, Thomas E.

2014-01-01

Background The structure and dynamics of DNA are critically related to its function. Molecular dynamics (MD) simulations augment experiment by providing detailed information about the atomic motions. However, to date the simulations have not been long enough for convergence of the dynamics and structural properties of DNA. Methods MD simulations performed with AMBER using the ff99SB force field with the parmbsc0 modifications, including ensembles of independent simulations, were compared to long timescale MD performed with the specialized Anton MD engine on the B-DNA structure d(GCACGAACGAACGAACGC). To assess convergence, the decay of the average RMSD values over longer and longer time intervals was evaluated in addition to assessing convergence of the dynamics via the Kullback-Leibler divergence of principal component projection histograms. Results These MD simulations —including one of the longest simulations of DNA published to date at ~44 μs—surprisingly suggest that the structure and dynamics of the DNA helix, neglecting the terminal base pairs, are essentially fully converged on the ~1–5 μs timescale. Conclusions We can now reproducibly converge the structure and dynamics of B-DNA helices, omitting the terminal base pairs, on the μs time scale with both the AMBER and CHARMM C36 nucleic acid force fields. Results from independent ensembles of simulations starting from different initial conditions, when aggregated, match the results from long timescale simulations on the specialized Anton MD engine. General Significance With access to large-scale GPU resources or the specialized MD engine “Anton” it is possibly for a variety of molecular systems to reproducibly and reliably converge the conformational ensemble of sampled structures. PMID:25219455

Burbank, Shkaplerov, and Kuipers review crew procedures

NASA Image and Video Library

2012-03-24

ISS030-E-171111 (24 March 2012) --- NASA astronaut Dan Burbank (left), Expedition 30 commander; along with Russian cosmonaut Anton Shkaplerov (center) and European Space Agency astronaut Andre Kuipers, both flight engineers, review crew procedures in the Zvezda Service Module of the International Space Station in preparation of moving to the appropriate Soyuz vehicles, due to the possibility that space debris could pass close to the station. Burbank, Shkaplerov and Ivanishin sheltered in the Soyuz TMA-22 spacecraft attached to the Poisk Mini-Research Module 2 (MRM2) while Kononenko, Kuipers and Pettit took to the Soyuz TMA-03M docked to the Rassvet Mini-Research Module 1 (MRM-1).

New crew launches to ISS on This Week @NASA - November 28, 2014

NASA Image and Video Library

2014-11-28

NASA’s Terry Virts and Expedition 42/43 crewmates, Anton Shkaplerov of the Russian Federal Space Agency and the European Space Agency’s Samantha Cristoforetti, launched Nov. 23 at 4:01 p.m. Eastern Standard Time, from Baikonur, Kazakhstan. Almost six hours later, their Soyuz spacecraft docked to the International Space Station – where they joined Expedition 42 Commander Barry Wilmore of NASA, and Flight Engineers Alexander Samokutyaev and Elena Serova of Roscosmos – returning the station crew to its full complement of six people. Also, First 3-D printed object in space, Orion flight test update, New airborne Earth Science missions and Happy Thanksgiving from space!

[The early history of "Ecstasy"].

PubMed

Benzenhöfer, U; Passie, T

2006-01-01

There is no consensus in the literature regarding the early history of MDMA (Methylendioxymethamphetamine, so-called "Ecstasy"). Various authors credit the first synthesis of MDMA to the German chemist Fritz Haber, but it appears neither in his doctoral thesis (Berlin 1891) nor in his accompanying articles. The man who first synthesized MDMA was the chemist Dr. Anton Köllisch, who worked for the German pharmaceutical company Merck. He created MDMA as a by-product while trying to synthesize hydrastinin, a styptic substance. In 1912, Merck filed to patent the applied method of preparation. The patent was issued in 1914, yet no pharmaceutical testing followed at that time.

Darwin: German mystic or French rationalist?

PubMed

Ghiselin, Michael T

2015-01-01

The notion that Charles Darwin embraced the German Romantic tradition seems plausible, given the early influence of Alexander von Humboldt. But this view fails to do justice to other scientific traditions. Darwin was a protégé of the Englishman John Stevens Henslow and was a follower of the Scott Charles Lyell. He had important debts to French scientists, notably Henri Milne-Edwards, Etienne and Isidore Geoffroy Saint-Hilaire, and Alphonse de Candolle. Many Germans were quite supportive of Darwin, but not all of these were encumbered by idealistic metaphysical baggage. Both Darwin and Anton Dohrn treated science as very much a cosmopolitan enterprise.

Expedition 55 Soyuz Docking

NASA Image and Video Library

2018-03-23

Icons for the International Space Station and Soyuz MS-08 spacecraft are seen on a tracking map on a screen in the Moscow Mission Control Center as the spacecraft approaches for docking, Friday, March 23, 2018 in Korolev, Russia. The Soyuz MS-08 spacecraft carrying Expedition 55-56 crewmembers Oleg Artemyev of Roscosmos and Ricky Arnold and Drew Feustel of NASA docked at 3:40 p.m. Eastern time (10:40 p.m. Moscow time) on March 23 and joined Expedition 55 Commander Anton Shkaplerov of Roscosmos, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA). Photo Credit: (NASA/Joel Kowsky)

Expedition 54 Soyuz Docking

NASA Image and Video Library

2017-12-19

Anton Shkaplerov of Roscosmos is seen after the opening of the hatches between the Soyuz MS-07 spacecraft and the International Space Station on the screens in the Moscow Mission Control Center in Korolev, Russia a few hours after the Soyuz MS-07 docked to the International Space Station on Tuesday, Dec. 19, 2017. Hatches were opened at 5:55 a.m. EST and Shkaplerov, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) joined Expedition 54 Commander Alexander Misurkin of Roscosmos and crewmates Mark Vande Hei and Joe Acaba of NASA aboard the orbiting laboratory. Photo Credit: (NASA/Joel Kowsky)

Expedition 55 Soyuz Docking

NASA Image and Video Library

2018-03-23

Guests watch a live view of the International Space Station, as seen by cameras onboard the Soyuz MS-08 spacecraft with Expedition 55-56 crewmembers Oleg Artemyev of Roscosmos and Ricky Arnold and Drew Feustel of NASA, on screens at the Moscow Mission Control Center as the spacecraft approaches for docking, Friday, March 23, 2018 in Korolev, Russia. The Soyuz MS-08 spacecraft carrying Artemyev, Feustel, and Arnold docked at 3:40 p.m. Eastern time (10:40 p.m. Moscow time) and joined Expedition 55 Commander Anton Shkaplerov of Roscosmos, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA). Photo Credit: (NASA/Joel Kowsky)

Expedition 55 Soyuz Docking

NASA Image and Video Library

2018-03-23

A live view of the International Space Station, as seen by cameras onboard the Soyuz MS-08 spacecraft with Expedition 55-56 crewmembers Oleg Artemyev of Roscosmos and Ricky Arnold and Drew Feustel of NASA, is seen on screens at the Moscow Mission Control Center as the spacecraft approaches for docking, Friday, March 23, 2018 in Korolev, Russia. The Soyuz MS-08 spacecraft carrying Artemyev, Feustel, and Arnold docked at 3:40 p.m. Eastern time (10:40 p.m. Moscow time) and joined Expedition 55 Commander Anton Shkaplerov of Roscosmos, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA). Photo Credit: (NASA/Joel Kowsky)

Expedition 54 Soyuz Docking

NASA Image and Video Library

2017-12-19

Icons for the International Space Station and Soyuz MS-07 spacecraft are seen on a tracking map on a screen in the Moscow Mission Control Center as the spacecraft approaches for docking, Tuesday, Dec. 19, 2017 in Korolev, Russia. The Soyuz MS-07 spacecraft carrying Anton Shkaplerov of Roscosmos, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) docked with the International Space Station at 3:39 a.m. EST, Tuesday, Dec. 19 while 250 statute miles over the southern coast of Italy and joined Expedition 54 Commander Alexander Misurkin of Roscosmos, and NASA astronauts Joe Acaba and Mark Vande Hei. Photo Credit: (NASA/Joel Kowsky)

Expedition 30 crewmembers look at crew procedures in the SM

NASA Image and Video Library

2012-03-24

ISS030-E-173973 (24 March 2012) --- NASA astronaut Dan Burbank (second left), Expedition 30 commander; along with Russian cosmonauts Oleg Kononenko (left) and Anton Shkaplerov and NASA astronaut Don Pettit, all flight engineers, are pictured in the Zvezda Service Module of the International Space Station as they prepare to move to the appropriate Soyuz vehicles, due to the possibility that space debris could pass close to the station. Burbank, Shkaplerov and Ivanishin sheltered in the Soyuz TMA-22 spacecraft attached to the Poisk Mini-Research Module 2 (MRM2) while Kononenko, Kuipers and Pettit took to the Soyuz TMA-03M docked to the Rassvet Mini-Research Module 1 (MRM-1).

Seafloor Soil Sampling and Geotechnical Parameter Determination - Handbook

DTIC Science & Technology

1979-08-01

Ko + Au(I- Ko )] (7-1) 97 I where ;v = effective overburden pressure (Section 6.1.3) K 0 = coefficient of lateral earLh pressure AU = reference pore...sin i+(6/a Vcos i su [ Ko i 0 V(7-2) a 1 + (2 A -1) sin 4 Vf 99 to oiU - ~1 where ; = overburden pressure ot depth where strength, Su, is to be...Rickivdo ANtON TfIW)I* SKO 11"will NY tIAltA. JOh I~ 11 Acwtx. CO IIRAI Ir/ IA M6I~. CA IIKOWN. RODEIRT Unoily. At. IIUILOCK 1.3 Ju4 I.AYri3X lt,! WA WM TA IIIf O~mc CA 128

Expedition_55_Post_Landing_Activities_June_4_2018_661449

NASA Image and Video Library

2018-06-04

Expedition 55 Crew Receives a Warm Welcome in Kazakhstan-------- Expedition 55 Commander Anton Shkaplerov of Roscosmos and Flight Engineers Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) were greeted in a traditional ceremony at the airport in Karaganda, Kazakhstan June 3, a few hours after landing in their Soyuz MS-07 spacecraft in Kazakhstan near the town of Dzhezkazgan. After the ceremony, the crew split up, with Shkaplerov returning to his training base in Star City, Russia, while Tingle and Kanai flew back to their homes in Houston on a NASA jet. The trio spent almost six months in space. The footage includes interviews with Tingle at the Karaganda airport.

Proceedings of the Conference on the Design of Experiments in Army Research Development and Testing (20th). Held at Army Operational Test and Evaluation Agency and Army Engineer Center at Fort Belvoir, VA., on 23-25 October 1974. Part 1

DTIC Science & Technology

1975-06-01

Anton Hauschild, Manufactur ing Technology D i r e c t o r a t e , Frankford Arsonal , P h i l a d e l p h i a , Pennsy lvania RATE DEPENDENT...Bethesda, Mary land OBSERVAT I ONS ON THE ALGEBRA OF NON-N0R;IAL FUNCT 1 ONS Donald M, Neal, Mechanics Research Laboratory, A r m y M a t e r i a l...a r a c t e r i s t i c func t ions i n combination wi th elementary m a t r i x a l g e b r a , he demonstrated t h e independence of I I v

Expedition 55 Soyuz Docking

NASA Image and Video Library

2018-03-24

Expedition 55 flight engineer Ricky Arnold of NASA is seen after the hatches were opened between the Soyuz MS-08 spacecraft and the International Space Station on screens at the Moscow Mission Control Center in Korolev, Russia, Saturday, March 24, 2018, a few hours after the Soyuz MS-08 docked to the International Space Station. Hatches were opened at 5:48 p.m. Eastern time on March 23 (12:48 a.m. Moscow time on March 24) and Arnold, Oleg Artemyev of Roscosmos, and Drew Feustel of NASA joined Expedition 55 Commander Anton Shkaplerov of Roscosmos, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) onboard the orbiting laboratory. Photo Credit: (NASA/Joel Kowsky)

Expedition 55 Soyuz Docking

NASA Image and Video Library

2018-03-24

Expedition 55 flight engineer Drew Feustel of NASA is seen after the hatches were opened between the Soyuz MS-08 spacecraft and the International Space Station on screens at the Moscow Mission Control Center in Korolev, Russia, Saturday, March 24, 2018, a few hours after the Soyuz MS-08 docked to the International Space Station. Hatches were opened at 5:48 p.m. Eastern time on March 23 (12:48 a.m. Moscow time on March 24) and Feustel, Oleg Artemyev of Roscosmos, and Ricky Arnold of NASA joined Expedition 55 Commander Anton Shkaplerov of Roscosmos, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) onboard the orbiting laboratory. Photo Credit: (NASA/Joel Kowsky)

Expedition 54 Soyuz Docking

NASA Image and Video Library

2017-12-19

Scott Tingle of NASA is seen embracing Expedition 54 Commander Alexander Misurkin after the opening of the hatches between the Soyuz MS-07 spacecraft and the International Space Station on the screens in the Moscow Mission Control Center in Korolev, Russia a few hours after the Soyuz MS-07 docked to the International Space Station on Tuesday, Dec. 19, 2017. Hatches were opened at 5:55 a.m. EST and Tingle, Anton Shkaplerov of Roscosmos, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) joined Expedition 54 Commander Alexander Misurkin of Roscosmos and crewmates Mark Vande Hei and Joe Acaba of NASA aboard the orbiting laboratory. Photo Credit: (NASA/Joel Kowsky)

jsc2017e136057 - On a snowy night at Red Square Moscow, Expedition 54-55 backup crewmembers Sergey Prokopyev of the Russian Federal Space Agency (Roscosmos, left), Jeanette Epps of NASA (center) and Alexander Gerst of the European Space Agency (right) pay

NASA Image and Video Library

2017-11-30

jsc2017e136057 - On a snowy night at Red Square Moscow, Expedition 54-55 backup crewmembers Sergey Prokopyev of the Russian Federal Space Agency (Roscosmos, left), Jeanette Epps of NASA (center) and Alexander Gerst of the European Space Agency (right) pay homage at the Kremlin Wall where Russian space icons are interred in traditional pre-launch ceremonies Nov. 30. They are backups to Anton Shkaplerov of Roscosmos, Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA), who will launch from the Baikonur Cosmodrome in Kazakhstan on the Soyuz MS-07 spacecraft Dec. 17 for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

jsc2017e136055 - On a snowy night at Red Square in Moscow, Expedition 54-55 backup crewmember Jeanette Epps of NASA lays flowers at the Kremlin Wall where Russian space icons are interred in traditional pre-launch ceremonies Nov. 30. Looking on are backup

NASA Image and Video Library

2017-11-30

jsc2017e136055 - On a snowy night at Red Square in Moscow, Expedition 54-55 backup crewmember Jeanette Epps of NASA lays flowers at the Kremlin Wall where Russian space icons are interred in traditional pre-launch ceremonies Nov. 30. Looking on are backup crewmembers Sergey Prokopyev of the Russian Federal Space Agency (Roscosmos, left) and Alexander Gerst of the European Space Agency. They are backups to Anton Shkaplerov of Roscosmos, Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA), who will launch from the Baikonur Cosmodrome in Kazakhstan on the Soyuz MS-07 spacecraft Dec. 17 for a five-month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

E54-55 Change of Command Ceremony_622857_hires

NASA Image and Video Library

2018-02-27

Expedition 54 Crew Hands Over the Space Station to Expedition 55---- The reins of the International Space Station were passed from Alexander Misurkin of Roscosmos to his cosmonaut crewmate Anton Shkaplerov during a ceremony on the orbital laboratory on Feb. 26. Misurkin is returning to Earth with his Expedition 54 crewmates, Mark Vande Hei and Joe Acaba of NASA, in the Soyuz MS-06 spacecraft. They will land on the steppe of Kazakhstan Feb. 28 (Feb. 27, U.S. time) to complete a five-and-a-half-month mission. Shkaplerov remains on the station as commander of Expedition 55 along with Flight Engineers Scott Tingle of NASA and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA).

Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins.

PubMed

van Bilsen, Jolanda H M; Sienkiewicz-Szłapka, Edyta; Lozano-Ojalvo, Daniel; Willemsen, Linette E M; Antunes, Celia M; Molina, Elena; Smit, Joost J; Wróblewska, Barbara; Wichers, Harry J; Knol, Edward F; Ladics, Gregory S; Pieters, Raymond H H; Denery-Papini, Sandra; Vissers, Yvonne M; Bavaro, Simona L; Larré, Colette; Verhoeckx, Kitty C M; Roggen, Erwin L

2017-01-01

.aopwiki.org platform to expand the mechanistic data, improve the confidence in each of the proposed KE and key event relations (KERs), and allow for the identification of new, or refinement of established KE and KERs.

[The original German scholarly literature of medieval falconry and the history of its scientific research].

PubMed

Giese, Martina

2007-01-01

German scholarly literature (Fachliteratur) of the middle ages devoted to falconry falls into two main categories: Translations, mostly of latin works, and original treatises. After a short survey of falconry in the past, this article will discuss the original treatises and the history of their analysis since the 19th century. In this context it will deal with the research of the following scholars: Joseph von Hammer-Purgstall, Anton von Perger, Ernst von Dombrowski, Hermann Werth, Christoph von Biedermann and--most importantly--Kurt Lindner. The appendix contains the editio princeps of the German Münchener Rezeptar I from the codex unicus, München, Universitätsbibliothek, 80 Cod. ms. 354, fol. 31r-33r (dating from the 15th century).

jsc2014e049621

NASA Image and Video Library

2014-05-21

11-47-48: At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 40/41 backup crewmembers Terry Virts of NASA (left) and Samantha Cristoforetti of the European Space Agency (right) try their hand at a game of billiards May 21 as they head into the homestretch of pre-launch training. Virts, Cristoforetti and Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) are backing up the prime crew, Flight Engineer Alexander Gerst of the European Space Agency, Soyuz Commander Max Suraev of Roscosmos and NASA Flight Engineer Reid Wiseman, who will launch on May 29, Kazakh time, on the Soyuz TMA-13M spacecraft from the Baikonur Cosmodrome for a 5 ½ month mission on the International Space Station. NASA/Victor Zelentsov

The power of a musical instrument: Franklin, the Mozarts, Mesmer, and the glass armonica.

PubMed

Gallo, D A; Finger, S

2000-11-01

In 1761 Benjamin Franklin invented the armonica (often referred to as the glass harmonica), an instrument designed to simplify the playing of the musical glasses. The instrument immediately became popular and inspired compositions by Wolfgang Mozart, who had the opportunity to hear and play one at the house of Franz Anton Mesmer. Armonica music was used by Mesmer in his séances, because he felt it could promote healing by propagating a mystical fluid that he called animal magnetism through the body. After Mesmer's theories were debunked by a highly respected panel of scientists, the armonica fell out of vogue. Because Franklin was on the panel that examined the discredited mesmerism, he indirectly contributed to his own invention's demise.

AM06: the Associative Memory chip for the Fast TracKer in the upgraded ATLAS detector

NASA Astrophysics Data System (ADS)

Annovi, A.; Beretta, M. M.; Calderini, G.; Crescioli, F.; Frontini, L.; Liberali, V.; Shojaii, S. R.; Stabile, A.

2017-04-01

This paper describes the AM06 chip, which is a highly parallel processor for pattern recognition in the ATLAS high energy physics experiment. The AM06 contains memory banks that store data organized in 18 bit words; a group of 8 words is called "pattern". Each AM06 chip can store up to 131 072 patterns. The AM06 is a large chip, designed in 65 nm CMOS, and it combines full-custom memory arrays, standard logic cells and serializer/deserializer IP blocks at 2 Gbit/s for input/output communication. The overall silicon area is 168 mm2 and the chip contains about 421 million transistors. The AM06 receives the detector data for each event accepted by Level-1 trigger, up to 100 kHz, and it performs a track reconstruction based on hit information from channels of the ATLAS silicon detectors. Thanks to the design of a new associative memory cell and to the layout optimization, the AM06 consumption is only about 1 fJ/bit per comparison. The AM06 has been fabricated and successfully tested with a dedicated test system.

Observations of toroidicity-induced Alfvén eigenmodes in a reversed field pinch plasma

NASA Astrophysics Data System (ADS)

Regnoli, G.; Bergsâker, H.; Tennfors, E.; Zonca, F.; Martines, E.; Serianni, G.; Spolaore, M.; Vianello, N.; Cecconello, M.; Antoni, V.; Cavazzana, R.; Malmberg, J.-A.

2005-04-01

High frequency peaks in the spectra of magnetic field signals have been detected at the edge of Extrap-T2R [P. R. Brunsell, H. Bergsåker, M. Cecconello, J. R. Drake, R. M. Gravestijn, A. Hedqvist, and J.-A. Malmberg, Plasma Phys. Controlled Fusion, 43, 1457 (2001)]. The measured fluctuation is found to be mainly polarized along the toroidal direction, with high toroidal periodicity n and Alfvénic scaling (f∝B/√mini ). Calculations for a reversed field pinch plasma predict the existence of an edge resonant, high frequency, high-n number toroidicity-induced Alfvén eigenmode with the observed frequency scaling. In addition, gas puffing experiments show that edge density fluctuations are responsible for the rapid changes of mode frequency. Finally a coupling with the electron drift turbulence is proposed as drive mechanism for the eigenmode.

[Chemical Laboratory of Celje Queen (at 580th Anniversary of Bohemian coronation of Queen Barbara of Celje)].

PubMed

Južnič, Stanislav

2017-06-01

Barbara Celjska je bila gotovo najbogatejša alkimistka vseh časov. Prispevek skuša pojasniti kakšni poskusi so potekali v njenem laboratoriju in nakazati, katere tehniške kemijske naprave je utegnila pri tem uporabljati. Ker je bila večina leteh iz zlahka lomljivih snovi, bi bilo njihovo iskanje brškone brez haska, saj ni veliko upanja za njihovo ohranitev. Barbara of Cilli was certainly the richest female alchemist of all times. The article tries to explain what kind of experiments she carried out in her laboratory and indicate which technical chemical plant she likely has used. The major part of her expensive tools was made from easily breakable materials, therefore any contemporary pursuit to locate them will be probably in vain, because there is not much hope for their preservation.

Quotable physics

NASA Astrophysics Data System (ADS)

Chomet, Seweryn

2008-03-01

Anton Capri is an alumnus of Princeton University, where he specialized in quantum field theory, and, since 1998, has been a distinguished professor emeritus at the University of Alberta in Canada. Since his nominal retirement he has devoted much of his time to writing and has now published, among other things, two linked books that present a variety of anecdotes involving famous physicists, as well as useful biographical sketches of them. The origin of these books is clearly defined by their author. "I have not any pretensions to having produced a 'scholarly' work," he writes. "Some of the stories recorded here are gossip, or physics folklore. I have tried to verify as many of the stories as I could, but I have not hesitated to include all stories that I heard and noted down."

Partial Molar Volumes of 15-Crown-5 Ether in Mixtures of N,N-Dimethylformamide with Water.

PubMed

Tyczyńska, Magdalena; Jóźwiak, Małgorzata

2014-01-01

The density of 15-crown-5 ether (15C5) solutions in the mixtures of N,N -dimethylformamide (DMF) and water (H 2 O) was measured within the temperature range 293.15-308.15 K using an Anton Paar oscillatory U-tube densimeter. The results were used to calculate the apparent molar volumes ( V Φ ) of 15C5 in the mixtures of DMF + H 2 O over the whole concentration range. Using the apparent molar volumes and Redlich and Mayer equation, the standard partial molar volumes of 15-crown-5 were calculated at infinite dilution ([Formula: see text]). The limiting apparent molar expansibilities ( α ) were also calculated. The data are discussed from the point of view of the effect of concentration changes on interactions in solution.

[A nosology for supernatural phenomena and the construction of the 'possessed' brain in the nineteenth century].

PubMed

Goncalves, Valeria Portugal; Ortega, Francisco

2013-06-01

At the end of the twentieth century, supernatural phenomena such as so called trances and possession by spirits received a scientific classification, which includes the numerous diagnoses of the dominant psychiatry. At the end of the nineteenth century we can observe a process of scientific categorization of phenomena considered to have originated in superstition or popular imagination. In this work we show how trances and spiritual possession were studied by Franz Anton Mesmer and his followers when developing the concept of magnetism; by James Braid during the creation of his theory of hypnosis; and by Jean Martin Charcot, which marked the entry of hysteria into nosological classification. Despite the differences between these schools, we identify the use of the brain and cerebral metaphors as the foundation of theories of the mind.

A review of the Magnus effect in aeronautics

NASA Astrophysics Data System (ADS)

Seifert, Jost

2012-11-01

The Magnus effect is well-known for its influence on the flight path of a spinning ball. Besides ball games, the method of producing a lift force by spinning a body of revolution in cross-flow was not used in any kind of commercial application until the year 1924, when Anton Flettner invented and built the first rotor ship Buckau. This sailboat extracted its propulsive force from the airflow around two large rotating cylinders. It attracted attention wherever it was presented to the public and inspired scientists and engineers to use a rotating cylinder as a lifting device for aircraft. This article reviews the application of Magnus effect devices and concepts in aeronautics that have been investigated by various researchers and concludes with discussions on future challenges in their application.

jsc2014e045101

NASA Image and Video Library

2014-05-15

1535: With the statue of Vladimir Lenin in the background at the Gagarin Cosmonaut Training Center in Star City, Russia, the Expedition 40/41 prime and backup crewmembers pose for pictures May 15 prior to their departure for the Baikonur Cosmodrome in Kazakhstan for final pre-launch training. From left to right are backup crewmembers Terry Virts of NASA, Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) and Samantha Cristoforetti of the European Space Agency, and prime crewmembers Alexander Gerst of the European Space Agency, Soyuz Commander Max Suraev of Roscosmos and Reid Wiseman of NASA. Wiseman, Suraev and Gerst will launch on May 29, Kazakh time, in the Soyuz TMA-13M spacecraft from Baikonur for a 5 ½ month mission on the International Space Station. NASA/Stephanie Stoll

"Franklin: Science, Politics and France"

NASA Astrophysics Data System (ADS)

McClellan, James E., III

2003-04-01

This presentation traces Benjamin Franklin's career as a "civic scientist" in Old-Regime France. It outlines the initial - and not always positive - reception of Franklin's work on electricity by the community of French scientists in the 1750s. It sketches Franklin's subsequent elevation into the pantheon of French Enlightenment heros, and it details his work as a "civic scientist" while American envoy to France in the 1770s and 1780s, notably his service on the government-sponsored commissions that repudiated the scientific and medical claims of Franz Anton Mesmer. This presentation concludes by examining a few features of Franklin's career that are not completely congruent with our notion of what a "civic scientist" might be, a contrast that is intended to illuminate both Franklin and the concept of "civic scientist."

Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence.

PubMed

Becker, Richard A; Ankley, Gerald T; Edwards, Stephen W; Kennedy, Sean W; Linkov, Igor; Meek, Bette; Sachana, Magdalini; Segner, Helmut; Van Der Burg, Bart; Villeneuve, Daniel L; Watanabe, Haruna; Barton-Maclaren, Tara S

2015-08-01

Systematic consideration of scientific support is a critical element in developing and, ultimately, using adverse outcome pathways (AOPs) for various regulatory applications. Though weight of evidence (WoE) analysis has been proposed as a basis for assessment of the maturity and level of confidence in an AOP, methodologies and tools are still being formalized. The Organization for Economic Co-operation and Development (OECD) Users' Handbook Supplement to the Guidance Document for Developing and Assessing AOPs (OECD 2014a; hereafter referred to as the OECD AOP Handbook) provides tailored Bradford-Hill (BH) considerations for systematic assessment of confidence in a given AOP. These considerations include (1) biological plausibility and (2) empirical support (dose-response, temporality, and incidence) for Key Event Relationships (KERs), and (3) essentiality of key events (KEs). Here, we test the application of these tailored BH considerations and the guidance outlined in the OECD AOP Handbook using a number of case examples to increase experience in more transparently documenting rationales for assigned levels of confidence to KEs and KERs, and to promote consistency in evaluation within and across AOPs. The major lessons learned from experience are documented, and taken together with the case examples, should contribute to better common understanding of the nature and form of documentation required to increase confidence in the application of AOPs for specific uses. Based on the tailored BH considerations and defining questions, a prototype quantitative model for assessing the WoE of an AOP using tools of multi-criteria decision analysis (MCDA) is described. The applicability of the approach is also demonstrated using the case example aromatase inhibition leading to reproductive dysfunction in fish. Following the acquisition of additional experience in the development and assessment of AOPs, further refinement of parameterization of the model through expert

A wavelength dependent investigation of the indole photophysics via ionization and fragmentation pump-probe spectroscopies.

PubMed

Godfrey, T J; Yu, Hui; Biddle, Michael S; Ullrich, Susanne

2015-10-14

A wavelength dependent study investigating the low-lying (1)La and (1)Lb states, both possessing (1)ππ* character, and the (1)πσ* state in the deactivation process of indole is presented here. Relaxation dynamics following excitation at 241, 250, 260, 270, 273, and 282 nm are examined using three gas-phase, pump-probe spectroscopic techniques: (1) hydrogen atom (H-atom) time-resolved kinetic energy release (TR-KER), (2) time-resolved photoelectron spectroscopy (TR-PES), and (3) time-resolved ion yield (TR-IY). Applied in combination, a more complete picture of the indole relaxation dynamics may be gleaned. For instance, TR-PES experiments directly observe all relaxation pathways by probing the evolution of the excited states following photoexcitation; whereas, TR-KER measurements indirectly, yet specifically, probe for (1)πσ*-state activity through the detection of H-atoms eliminated along the indole nitrogen-hydrogen (N-H) stretch coordinate-a possible outcome of (1)πσ*-state relaxation in indole. In addition, mass information obtained via TR-IY monitors fragmentation dynamics that may occur within the neutral electronically excited and/or cationic states. The work herein assesses the onset and importance of the (1)πσ* state at various pump wavelengths by systematically tuning across the ultraviolet absorption spectrum of indole with a particular focus on those pump wavelengths longer than 263 nm, where the involvement of the (1)πσ* state is under current debate. As far as this experimental work is concerned, there does not appear to be any significant involvement by the (1)πσ* state in the indole relaxation processes following excitation at 270, 273, or 282 nm. This investigation also evaluates the primary orbital promotions contributing to the (1)La, (1)Lb, and (1)πσ* transitions based on ionization preferences observed in TR-PES spectra. Relaxation time constants associated with dynamics along these states are also reported for excitation at all

A comparison of different synchronization measures in electroencephalogram during propofol anesthesia.

PubMed

Liang, Zhenhu; Ren, Ye; Yan, Jiaqing; Li, Duan; Voss, Logan J; Sleigh, Jamie W; Li, Xiaoli

2016-08-01

Electroencephalogram (EEG) synchronization is becoming an essential tool to describe neurophysiological mechanisms of communication between brain regions under general anesthesia. Different synchronization measures have their own properties to reflect the changes of EEG activities during different anesthetic states. However, the performance characteristics and the relations of different synchronization measures in evaluating synchronization changes during propofol-induced anesthesia are not fully elucidated. Two-channel EEG data from seven volunteers who had undergone a brief standardized propofol anesthesia were then adopted to calculate eight synchronization indexes. We computed the prediction probability (P K ) of synchronization indexes with Bispectral Index (BIS) and propofol effect-site concentration (C eff ) to quantify the ability of the indexes to predict BIS and C eff . Also, box plots and coefficient of variation were used to reflect the different synchronization changes and their robustness to noise in awake, unconscious and recovery states, and the Pearson correlation coefficient (R) was used for assessing the relationship among synchronization measures, BIS and C eff . Permutation cross mutual information (PCMI) and determinism (DET) could predict BIS and follow C eff better than nonlinear interdependence (NI), mutual information based on kernel estimation (KerMI) and cross correlation. Wavelet transform coherence (WTC) in α and β frequency bands followed BIS and C eff better than that in other frequency bands. There was a significant decrease in unconscious state and a significant increase in recovery state for PCMI and NI, while the trends were opposite for KerMI, DET and WTC. Phase synchronization based on phase locking value (PSPLV) in δ, θ, α and γ1 frequency bands dropped significantly in unconscious state, whereas it had no significant synchronization in recovery state. Moreover, PCMI, NI, DET correlated closely with each other and they

Experimentelles FMCW-Radar zur hochfrequenten Charakterisierung von Windenergieanlagen

NASA Astrophysics Data System (ADS)

Schubert, Karsten; Werner, Jens; Schwartau, Fabian

2017-09-01

During the increasing dissemination of renewable energy sources the potential and actual interference effects of wind turbine plants became obvious. Turbines reflect the signals of weather radar and other radar systems. In addition to the static radar echoes, in particular the Doppler echoes are to be mentioned as an undesirable impairment Keränen (2014). As a result, building permit is refused for numerous new wind turbines, as the potential interference can not be reliably predicted. As a contribution to the improvement of this predictability, measurements are planned which aim at the high-frequency characterisation of wind energy installations. In this paper, a cost-effective FMCW radar is presented, which is operated in the same frequency band (C-band) as the weather radars of the German weather service. Here, the focus is on the description of the hardware design including the considerations used for its dimensioning.

Word Frequency Analysis. MOS: 62J. Skill Levels 1 & 2.

DTIC Science & Technology

1981-05-01

WCRDI COUNT2 W OR u, CO UIT 3 WORD 3 COUNT’. kCRD4 I CELL 9 CLNTER I CERERLINE t CENTRALLY 2 C [JTP I FGAL 2 CZRT..IN I CESSIVE 46 LFI’ 14 C H%1% ~ 4...4 .4* 4 AD ,G4 ANGLI 4 fC S 0A 4 r. 5 54b d204 4 BE- J 4OCK4 ECAGNE 4 TTA .(.KFTS 4 B𔃻E.KER 4 44 CC!’PPCT 4 13FL*.~If 4 CCLC CTwV7CCC~L< EL4 CO 4 CE...t CI RE I CARTcUL I CAR7~ I 3 CARRY I CAL 7I C!! 11 E t C., TFPS I CA~TCH I C4TEO I co usIN Kr I CL TC1 I CELL 1CTNlERL!NEz I ’ENI P.LIY Ic3VEI

On the history of dissociative identity disorders in Germany: the doctor Justinus Kerner and the girl from Orlach, or possession as an "exchange of the self".

PubMed

Peter, Burkhard

2011-01-01

The history of hypnosis is closely linked to the theme of possession; one such link is that the forerunner of hypnosis, animal magnetism, replaced exorcism in 1775 when Franz Anton Mesmer testified against Father Johann Joseph Gassner's exorcism. Modern authors have noted remarkable similarities between states of possession and dissociation. The treatment of possession by animal magnetism and exorcism represents the special romantic-magnetic therapy of the German medical doctor Justinus Kerner in the early 19th century. This article describes the man, his methods, and his thinking and presents one of his most famous case studies, the girl from Orlach, which, by today's standards, was a true case of dissociative identity disorder (DID). This article describes how contemporary principles of treatment were used and controversial issues about the nature and causes of DID were discussed 175 years ago.

[Emission of volatile components in carpenter's kumylotox into air].

PubMed

Jodynis-Liebert, J; Kiejnowska, M

1991-01-01

Study was made of Carpenter's Kumylotox, a fungicidal preparation containing: p-cumylphenol, dibutyl phthalate, machine oil, chloroparaffin, a 15% solution of ker-1500 rubber in painter's naphta, and petrol for pastas. The preparation was applied onto boards placed in an experimental chamber at 1-week intervals. In air of the chamber, dibutyl phthalate and p-cumylphenol were determined quantitatively by gas chromatography. The presence of hydrocarbons was recorded by the same method, without quantitative determination. Analyses were continued until the disappearance of the investigated from air. It was found that already after 2 weeks the p-cumylphenol level dropped below the allowable concentration amounting to 0.015 mg/dm3. The dibutyl phthalate level decreased to the allowable concentration (0.05 mg/m3) only after 9 weeks of board ageing. According to analysis by the GC-MS method, aromatic hydrocarbons disappeared from the chamber's air already after 5 weeks, and the remaining hydrocarbons--after 9 weeks.

Canna edulis Leaf Extract-Mediated Preparation of Stabilized Silver Nanoparticles: Characterization, Antimicrobial Activity, and Toxicity Studies.

PubMed

Otari, S V; Pawar, S H; Patel, Sanjay K S; Singh, Raushan K; Kim, Sang-Yong; Lee, Jai Hyo; Zhang, Liaoyuan; Lee, Jung-Kul

2017-04-28

A novel approach to synthesize silver nanoparticles (AgNPs) using leaf extract of Canna edulis Ker-Gawl. (CELE) under ambient conditions is reported here. The as-prepared AgNPs were analyzed by UV-visible spectroscopy, transmission emission microscopy, X-ray diffraction, Fourier transform-infrared spectroscopy, energy-dispersive analysis of X-ray spectroscopy, zeta potential, and dynamic light scattering. The AgNPs showed excellent antimicrobial activity against various pathogens, including bacteria and various fungi. The biocompatibility of the AgNPs was analyzed in the L929 cell line using NRU and MTT assays. Acridine orange/ethidium bromide staining was used to determine whether the AgNPs had necrotic or apoptotic effects on L929 cells. The concentration of AgNPs required for 50% inhibition of growth of mammalian cells is far more than that required for inhibition of pathogenic microorganisms. Thus, CELE is a candidate for the eco-friendly, clean, cost-effective, and nontoxic synthesis of AgNPs.

The influence of granting npk fertilizer and nanosilic fertilizers on the growth of Ganyong plant (Canna edulis Ker.)

NASA Astrophysics Data System (ADS)

Barita, Yahya; Prihastanti, Erma; Haryanti, Sri; Subagio, Agus; Ngadiwiyana

2018-05-01

Ganyong is a herbaceous plant which included in the tuberous plant group. One of the ways to increase the growth of ganyong plants is by combining Nanosilica and NPK. Nanosilica is an fertilizer with nutrient contain nano size of silica. This research was conducted using Completely Randomized Design (CRD) and consisted of 6 treatments with 3 replication were control (without nanosil and NPK fertilizers); (combination 0% nanosilic and 100% NPK); (combination 25% nanosilic and 75% NPK); (50% nanosilic and 50% NPK); (75% nanosilic and 25% NPK) and (100% nanosilic and 0% NPK). Parameters of this research consisted stomata and growth rate: plant height, leaf quantity, leaf color, wet weight and dry weight. Analysis of Variance (Anova) were used to analyze the data, and if significant difference were found, the data tested further by Duncan Multiple Range Test (DMRT) at 95% significant level. The results showed that the combination of Nanosilica and NPK fertilizers affected plant height, dry weight and wet weight of the plant. The combination of 75% nanosil fertilizer and 25% optimal NPK fertilizer increased plant height, dry weight and wet weight on ganyong. The combination of nanosilic and NPK did not affected to amount stomata in ganyong.

The effect of photo-activated glazes on the microhardness of acrylic baseplate resins.

PubMed

Emmanouil, J K; Kavouras, P; Kehagias, Th

2002-01-01

A comparative investigation of acrylic denture base surface microhardness, induced through glazing with different photo-activated liquids. Thermopolymerized acrylic resin Paladon 65 (Kulzer) was used for this study. The samples were mechanically thinned by silicon carbide grinding papers and finally, mechanically polished by alumina pastes. The samples were then glazed with Palaseal, Plaquit and Lightplast-Lack photo-activated liquids. Microhardness tests were carried out via a Zeiss optical microscope equipped with an Anton Paar microhardness tester fitted with a Knoop indenter. Microhardness testing performed on surfaces glazed by Plaquit, Lightplast-Lack, and Palaseal photo-activated liquids showed enhanced microhardness values compared to the mechanically polished acrylic resin denture base material. Comparative microhardness tests performed on acrylic base resin treated with photo-activated acrylic glazes showed that all increases the surface microhardness. The enhancement of surface microhardness of acrylic denture bases suggests that they are likely to resist wear during service.

jsc2017e138127 - At the Baikonur Cosmodrome in Kazakhstan, the Expedition 54-55 prime and backup crewmembers pose for pictures Dec. 13 in front of the cottage where the iconic Russian space designer Sergey Korolev slept on the night before Yuri Gagarin la

NASA Image and Video Library

2017-12-13

jsc2017e138127 - At the Baikonur Cosmodrome in Kazakhstan, the Expedition 54-55 prime and backup crewmembers pose for pictures Dec. 13 in front of the cottage where the iconic Russian space designer Sergey Korolev slept on the night before Yuri Gagarin launched April 12, 1961 to become the first human to fly in space. Korolev’s cottage is next to the cottage where Gagarin slept on the eve of his launch. From left to right are backup crewmembers Alexander Gerst of the European Space Agency, Sergey Prokopyev of the Russian Federal Space Agency (Roscosmos) and Jeanette Epps of NASA, and prime crewmembers Scott Tingle of NASA, Anton Shkaplerov of Roscosmos and Norishige Kanai of the Japan Aerospace Exploration Agency. Tingle, Kanai and Shkaplerov will launch Dec. 17 on the Soyuz MS-07 spacecraft for a five month mission on the International Space Station...Andrey Shelepin/Gagarin Cosmonaut Training Center.

Bell's palsy before Bell: Cornelis Stalpart van der Wiel's observation of Bell's palsy in 1683.

PubMed

van de Graaf, Robert C; Nicolai, Jean-Philippe A

2005-11-01

Bell's palsy is named after Sir Charles Bell (1774-1842), who has long been considered to be the first to describe idiopathic facial paralysis in the early 19th century. However, it was discovered that Nicolaus Anton Friedreich (1761-1836) and James Douglas (1675-1742) preceded him in the 18th century. Recently, an even earlier account of Bell's palsy was found, as observed by Cornelis Stalpart van der Wiel (1620-1702) from The Hague, The Netherlands in 1683. Because our current knowledge of the history of Bell's palsy before Bell is limited to a few documents, it is interesting to discuss Stalpart van der Wiel's description and determine its additional value for the history of Bell's palsy. It is concluded that Cornelis Stalpart van der Wiel was the first to record Bell's palsy in 1683. His manuscript provides clues for future historical research.

Performance of magnetorheological elastomer based green epoxidized natural rubber/sucrose acetate isobutyrate hybrid matrix

NASA Astrophysics Data System (ADS)

Khairi, Muntaz Hana Ahmad; Amri Mazlan, Saiful; Aziz, Siti Aishah Abdul; Ubaidillah; Tan Shilan, Salihah

2018-04-01

This study introduces a sucrose acetate isobutyrate (SAIB) as a novel additive of magnetorheological elastomers (MREs). The MREs utilized an epoxidized natural rubber (ENR) as the matrix and carbonyl iron particles (CIPs) as their filler. The CIPs were fixed at 60 wt%. The viscosity of the compound was observed using a viscometer. Meanwhile, the microstructures were observed by using field emission scanning electron microscope (FESEM). Rheological properties regarding shear storage modulus were measured by using a rheometer (MCR 302, Anton Paar). The experimental results demonstrated that the MREs-based ENR/SAIB had a decrement in their viscosity by 40% reduction. Moreover, the magnetorheological (MR) effect increased by 23% as the increment of magnetic fields. The morphological photograph showed that the CIPs embedded well within the matrix. The fabricated MREs samples were strain dependent, where all MREs samples exhibit the deteriorating trend when increasing the strain amplitude.

The New Physics

NASA Astrophysics Data System (ADS)

Fraser, Gordon

2006-04-01

Introduction Gordon Fraser; Part I. Matter and the Universe: 1. Cosmology Wendy Freedman and Rocky Kolb; 2. Gravity Ronald Adler; 3. Astrophysics Arnon Dar; 4. Particles and the standard model Chris Quigg; 5. Superstrings Michael Green; Part II. Quantum Matter: 6. Atoms and photons Claude Cohen-Tannoudji and Jean Dalibard; 7. The quantum world of ultra-cold atoms Christopher Foot and William Phillips; 8. Superfluidity Henry Hall; 9. Quantum phase transitions Subir Sachdev; Part III. Quanta in Action: 10. Quantum entanglement Anton Zeilinger; 11. Quanta, ciphers and computers Artur Ekert; 12. Small-scale structure and nanoscience Yoseph Imry; Part IV. Calculation and Computation: 13. Nonlinearity Henry Abarbanel; 14. Complexity Antonio Politi; 15. Collaborative physics, e-science and the grid Tony Hey and Anne Trefethen; Part V. Science in Action: 16. Biophysics Cyrus Safinya; 17. Medical physics Nicolaj Pavel; 18. Physics and materials Robert Cahn; 19. Physics and society Ugo Amaldi.

The New Physics

NASA Astrophysics Data System (ADS)

Fraser, Gordon

2009-08-01

Introduction Gordon Fraser; Part I. Matter and the Universe: 1. Cosmology Wendy Freedman and Rocky Kolb; 2. Gravity Ronald Adler; 3. Astrophysics Arnon Dar; 4. Particles and the standard model Chris Quigg; 5. Superstrings Michael Green; Part II. Quantum Matter: 6. Atoms and photons Claude Cohen-Tannoudji and Jean Dalibard; 7. The quantum world of ultra-cold atoms Christopher Foot and William Phillips; 8. Superfluidity Henry Hall; 9. Quantum phase transitions Subir Sachdev; Part III. Quanta in Action: 10. Quantum entanglement Anton Zeilinger; 11. Quanta, ciphers and computers Artur Ekert; 12. Small-scale structure and nanoscience Yoseph Imry; Part IV. Calculation and Computation: 13. Nonlinearity Henry Abarbanel; 14. Complexity Antonio Politi; 15. Collaborative physics, e-science and the grid Tony Hey and Anne Trefethen; Part V. Science in Action: 16. Biophysics Cyrus Safinya; 17. Medical physics Nicolaj Pavel; 18. Physics and materials Robert Cahn; 19. Physics and society Ugo Amaldi.

[Did the patients with chronic obstructive pulmonary disease in Primary Care center Anton de Borja correctly utilize inhalers?].

PubMed

Represas-Carrera, Francisco Jesús

2015-01-01

To determine the percentage of patients with Pulmonary Obstructive Chronic Disease who doing of incorrect form the inhaler technique. Descriptive transversal study made in the Primary Care Center "Antón de Borja" of Rubi (in Barcelona) during the period between May and December 2013, where it was studied a representative sample of 200 patients. To assess the inhaler technique was performed a personal interview with the patient in which it was requested him to carry out a demonstration of how he was using his inhaler regularly evaluating his inhaler technique by means of the regulations established by Spanish Society of Pneumology and Thoracic Surgery. 43% of the patients carry out inhaler technique incorrectly. The percentage of inadequate use of inhalers of dry powder was 26%, of the pressurized cartridge 38% and the inhaler chamber 10%. 82% of patients ≥ 65 years who have prescribed a pressurized inhaler cartridge do not perform accompanied by an inhaler chamber. A high percentage of patients do not correctly carry out inhaler technique, pointing the rare use made of the inhaler chamber despite its proven efficacy and the high number of patients with pressurized inhaler cartridge. These results reflect the need for the implementation of an educational program in our Primary Care Center to teach patients to use inhaler devices. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

An historical note on the cell theory.

PubMed

Ribatti, Domenico

2018-03-01

The development of the microscope was a precondition for the discovery of cells. This instrument magnifies objects too small to be seen by the naked eye. In 1673, the Dutch botanist, Anton van Leeuwenhoek, made a more advanced microscope and reported seeing a myriad of microscopic "animalcules" in water. He also made further studies of red blood cells and sperm cells. Most studies that followed were done on the easily studied plant tissues. Plant cells, rigidly encased in their cell walls, were ideal to study in situ. The cell theory proposes that nucleated cells are the basic structure of plants and animals. This concept was observed and published separately, first by the botanist, Matthias Schleiden, in 1838, and then by the zoologist, Theodor Schwann, in 1839. Their work demonstrated that cells form the basic unit of life of plants and animals. Rudolf Virchow concluded that all living organisms are the sum of single cellular units and that cells multiply. Copyright © 2018 Elsevier Inc. All rights reserved.

Research on data from the ATLAS experiment at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Purohit, Milind V.

2015-07-31

In this report senior investigator Prof. Milind V. Purohit describes research done with data from the ATLAS experiment at CERN. This includes preparing papers on the performance of the CSC detector, searches for SUSY using a new modern ''big data'' technique, and a search for supersymmetry (SUSY) using the "zero leptons razor" (0LRaz) technique. The prediction of the W=Z+jets background processes by the ATLAS simulation prior to the fit is found to be overestimated in the phase space of interest. In all new signal regions presented in this analysis the number of events observed is consistent with the post-fit SMmore » expectations. Assuming R-parity conservation, the limit on the gluino mass exceeds 1150 GeV at 95% confidence level, for an LSP mass smaller than 100 GeV. Other USC personnel who participated in this project during the period of this grant were a graduate student, Anton Kravchenko.« less

The New Physics and Cosmology - Dialogues with the Dalai Lama

NASA Astrophysics Data System (ADS)

Zajonc, Arthur; Houshmand, Zara

2004-03-01

What happens when the Dalai Lama meets with leading physicists and a historian? This book is the carefully edited record of the fascinating discussions at a Mind and Life conference in which five leading physicists and a historian (David Finkelstein, George Greenstein, Piet Hut, Arthur Zajonc, Anton Zeilinger, and Tu Weiming) discussed with the Dalai Lama current thought in theoretical quantum physics, in the context of Buddhist philosophy. A contribution to the science-religion interface, and a useful explanation of our basic understanding of quantum reality, couched at a level that intelligent readers without a deep involvement in science can grasp. In the tradition of other popular books on resonances between modern quantum physics and Zen or Buddhist mystical traditions--notably The Dancing Wu Li Masters and The Tao of Physics , this book gives a clear and useful update of the genuine correspondences between these two rather disparate approaches to understanding the nature of reality.

Corporeal elements and principles in the learned German chymical tradition.

PubMed

Klein, Joel A

2014-11-01

This paper explores diverse conceptions of the physicality and tangibility of elements and principles in early modern chymistry. By tracing the development of natural philosophical and corpuscular ideas about material elements and principles among several physicans and chymists, including Thomas Erastus, Andreas Libavius, Daniel Sennert, and Anton Günther Billich, this article locates a learned tradition that developed predominantly in Germany, and which directly challenged a common understanding of matter held by major Paracelsians as well as authors from the French textbook tradition. Likewise, conceptions of incorporeal elements or principles are shown to have developed from the ideas of Paracelsus and Petrus Severinus, whereas authors in the learned tradition emphasised a particular interpretation of Aristotle. The article concludes by suggesting that chymical interpretations of material composition had an important influence throughout the seventeenth and eighteenth centuries, and that this provides further evidence that the so-called "compositional revolution" in chemistry was well underway prior to the eighteenth century.

Resistive wall mode feedback control in EXTRAP T2R with improved steady-state error and transient response

NASA Astrophysics Data System (ADS)

Brunsell, P. R.; Olofsson, K. E. J.; Frassinetti, L.; Drake, J. R.

2007-10-01

Experiments in the EXTRAP T2R reversed field pinch [P. R. Brunsell, H. Bergsåker, M. Cecconello et al., Plasma Phys. Control. Fusion 43, 1457 (2001)] on feedback control of m =1 resistive wall modes (RWMs) are compared with simulations using the cylindrical linear magnetohydrodynamic model, including the dynamics of the active coils and power amplifiers. Stabilization of the main RWMs (n=-11,-10,-9,-8,+5,+6) is shown using modest loop gains of the order G ˜1. However, other marginally unstable RWMs (n=-2,-1,+1,+2) driven by external field errors are only partially canceled at these gains. The experimental system stability limit is confirmed by simulations showing that the latency of the digital controller ˜50μs is degrading the system gain margin. The transient response is improved with a proportional-plus-derivative controller, and steady-state error is improved with a proportional-plus-integral controller. Suppression of all modes is obtained at high gain G ˜10 using a proportional-plus-integral-plus-derivative controller.

[IPA secretary and patron--Freud's patient, financial administrator and friend. Anton von Freund's letters to Sigmund Freud (1916-1919)].

PubMed

Huppke, Andrea; Schröter, Michael

2011-01-01

Although the letters, of which numerous and lengthy excerpts are presented in this paper, have repeatedly been used by scholars, they have so far remained unpublished. There are 45 items, written between 4. 1. 1916 and 13. 7. 1919. They indicate a passionate transference to Freud, unfolding against the background of two Hungarian revolutions. After suffering a relapse of his cancer, v. Freund had several stretches of analysis with Freud. While he was better, he established two major funds: one of them allowing the foundation of the psychoanalytic publishing house, the other destined to sponsor a psychoanalytic clinic in Budapest. V. Freund helped organize the Budapest IPA congress, became a member of the "secret committee" and started to actively conduct analyses. Freud was very attached to him and felt deeply shaken by the inexorable progression of v. Freund's disease and then death in January 1920.

Mapping the isotopic signature of methane in South-Eastern Spain: complementing biogeochemical long-term research with short term observations

NASA Astrophysics Data System (ADS)

Àgueda, Alba; Morguí, Josep Anton; Vazquez Garcia, Eusebi; Curcoll, Roger; Lowry, David; Fisher, Rebecca E.; Nisbet, Euan G.

2016-04-01

will be helpful in the validation of transport models. *Corresponding author: Josep Anton Morguí - josep-anton.morgui@ic3.cat "The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) in the InGOS project under grant agreement n° 284274''

The Zach family in Hungary

NASA Astrophysics Data System (ADS)

Vargha, Magda

The Zach Family moved to Hungary. In the first decades of the 18th century the population was so low in Hungary that thousands of people moved into an almost empty country. In 1740 the physician Joseph Zach (1714-1792) came from Moravia to Esztergom which at that time had only 10 000 inhabitants. Soon he became the city doctor. It is very probable, that this was the place where he met Klara Sonntag, who became his wife. In any case, Zach moved to Pest, where he became the city doctor in 1746. The Invalide-Hospital built by Martinelli in 1726 was the biggest and most elegant house in Pest at that time - and it was giving shelter to 4000 invalids, whilst the city itself had only 11 000 inhabitants. There Zach became the ``protomedicus''. In 1751 Austrian Empress Maria Theresia visited this military hospital. She was so impressed by Zach's work that she honoured him with Hungarian nobility in 1765. From the corresponding official paper we know that he had three sons and three daughters. In 1791 he received citizenship in Pest. The Hungarian Magnates favoured the talented physician. The Lord Chief Justice Count György Fekete was also among his patients. His thirteen year-old son Count János Fekete became the godfather of Zach's son Franz Xaver Zach in 1754. It is very likely that Voltairian Count János Fekete influenced the personality of Franz Xaver von Zach. Galicia became Austrian Territory in 1772. Pater Liesganig was nominated to lead the Land-Survey Office of Galicia. Anton von Zach and Franz Xaver Zach were his co-workers in this very important task. At the same time Franz Zach became a professor of mechanics at Lemberg University and in its observatory he began his life-long astronomical observations. It is very probable that he joined the Freemasons here together with his godfather, now General, Jänos Fekete. Later they stayed in the same cities very often. The military and scientific works of the two Zach brothers Anton and Franz were so highly

Effect of different hardness nanoparticles on friction properties of magnetorheological fluids

NASA Astrophysics Data System (ADS)

Zhao, Mingmei; Zhang, Jinqiu; Yao, Jun

2017-10-01

Magnetorheological fluids (MRFs) exhibit different wear performance when nanoparticles with different hardness are added. In this study, three solid particles with different hardness are considered to study the variation in MRF performance. The friction and wear properties of the MRF are measured by using a four-ball friction and wear tester, and the surface of the steel ball was observed using a three-dimensional white light interferometer. Also, the rheological properties of MRF are tested by using an Anton-Paar rheometer. The results show that the addition of graphite yields a stable friction process and does not degrade the rheological properties of MRF. Nano-diamond increases the shear yield strength and reduces the wall slip to a greater extent. However, the wear is more serious in this case. Copper particles are unstable, and their surface activity is too high to get adsorbed on the surface of iron powder aggravating the settlement rate. The above three MRFs with different kinds of nano-particles present a more regular grinding spot, and the nano-particles have a certain repair function to the surface.

Next Space Station Crew Previews Mission

NASA Image and Video Library

2017-10-11

NASA astronaut Scott Tingle and crewmates Anton Shkaplerov of the Russian space agency Roscosmos and Norishege Kanai of the Japan Aerospace Exploration Agency (JAXA) discussed their upcoming mission to the International Space Station in a news conference on Oct. 11 at NASA’s Johnson Space Center in Houston. Tingle, Shkaplerov and Kanai will launch to the space station aboard the Soyuz MS-07 spacecraft on Dec. 17 from the Baikonur Cosmodrome in Kazakhstan. They will join the station’s Expedition 54 crew, and return to Earth in April 2018 as members of Expedition 55. During a planned four-month mission, the station crew members will take part in about 250 research investigations and technology demonstrations not possible on Earth in order to advance scientific knowledge of Earth, space, physical and biological sciences. Science conducted on the space station continues to yield benefits for humanity and will enable future long-duration human and robotic exploration into deep space, including missions past the Moon and Mars. This will be the first spaceflight for Tingle and Kanai, and the third for Shkaplerov.

History of the pharmacies in the town of Aleşd, Bihor county

PubMed Central

PAŞCA, MANUELA BIANCA; GÎTEA, DANIELA; MOISA, CORINA

2013-01-01

In 1848 pharmacist Horváth Mihály established the first pharmacy in Aleşd, called Speranţa (Remény). Following the brief history of this pharmacy we will notice that in 1874 the pharmacy comes into the possession of Kocsiss József. In 1906 the personal rights of the pharmacy are transcribed to Kocsiss Béla, and since 1938 the his son, Kocsiss Dezső, pharmacist, became the new owner. In 1949 the pharmacy was nationalized and became the property of the Pharmaceutical Office Oradea, the pharmacy got the name Farmacia nr. 22 of Aleşd, and continued its activity throughout the whole communist period. Starting with the year 1991 it entered into private system as Angefarm, as the property of Mermeze Gheorghe, pharmacist, and from 2003 until now works under the name Vitalogy 3, as the property of Ghitea Sorin. A second pharmacy, Sfântul Anton was founded in 1937 by pharmacist Herceg Dobreanu Atena, which however had no continuity during the communist period. PMID:26527963

Doctors in Court, Honour, and Professional Ethics: Two Scandals in Imperial Germany*

PubMed Central

Maehle, Andreas-Holger

2013-01-01

Summary Comparing two public medical affairs which involved disciplinary proceedings and libel actions, one from Bavaria and one from Prussia, this article analyzes the dynamics behind legal conflicts over doctors’ professional ethics in Imperial Germany. In both the case of Dr Maurice Hutzler, who committed suicide after conflicts with senior colleagues at the Gisela Children’s Hospital and a sentence of the court of honour of the Munich Medical District Society, and the Berlin ‘patient trade’ affair, in which the medical professors Ernst von Leyden, Hermann Senator, Karl Anton Ewald and Carl Posner were accused of having made payments to middlemen for bringing them lucrative private patients, notions of personal and professional honour played a central role. The Munich case highlighted shortcomings of the Bavarian medical court of honour system, which was less developed than its Prussian counterpart. The analysis of the two cases suggests that the ethics of medical practice in early twentieth-century Germany should be viewed as part of a culture of honour. PMID:22303773

An Equation of State for Hypersaline Water in Great Salt Lake, Utah, USA

USGS Publications Warehouse

Naftz, D.L.; Millero, F.J.; Jones, B.F.; Green, W.R.

2011-01-01

Great Salt Lake (GSL) is one of the largest and most saline lakes in the world. In order to accurately model limnological processes in GSL, hydrodynamic calculations require the precise estimation of water density (??) under a variety of environmental conditions. An equation of state was developed with water samples collected from GSL to estimate density as a function of salinity and water temperature. The ?? of water samples from the south arm of GSL was measured as a function of temperature ranging from 278 to 323 degrees Kelvin (oK) and conductivity salinities ranging from 23 to 182 g L-1 using an Anton Paar density meter. These results have been used to develop the following equation of state for GSL (?? = ?? 0.32 kg m-3): ?? - ??0 = 184.01062 + 1.04708 * S - 1.21061*T + 3.14721E - 4*S2 + 0.00199T2 where ??0 is the density of pure water in kg m-3, S is conductivity salinity g L-1, and T is water temperature in degrees Kelvin. ?? 2011 U.S. Government.

High resolution FTIR spectroscopic study of the ν4 band of CH 3CHF 2 enclosed in a flow of cold N 2 gas

NASA Astrophysics Data System (ADS)

Appadoo, Dominique R. T.; Robertson, Evan G.; McNaughton, Don

2003-01-01

An enclosive flow cooling (EFC) cell has been constructed, and coupled to a Brüker IFS 120HR high resolution Fourier transform spectrometer to record rotationally cold absorption spectra of gases of atmospheric interest at high spectral resolution. The new system has been characterized using N 2O, revealing that rotational temperatures as cold as 110 K are readily attainable using liquid nitrogen as a cryogen. Infrared spectra of the ν4 band of 1,1-difluoroethane (R152a), CH 3CHF 2, cooled in the EFC cell have been measured at a resolution of 0.0019 cm-1. Eight hundred and twenty rovibrational transitions of the weak ν4 band with 2⩽ J'⩽46 and Kc'⩽16 were assigned and fitted to Watson's A-reduced Hamiltonian. The ν4 CH 3 symmetric deformation ( a/c-type) was found to be coupled to the ν13 asymmetric deformation ( b-type) via an a-axis Coriolis interaction. In the ensuing analysis, values of spectroscopic constants were obtained for both the ν4 and dark ν13 states. Supporting ab initio calculations up to the MP2/TZV+(3 df,3 p) level are presented.

A hardware fast tracker for the ATLAS trigger

NASA Astrophysics Data System (ADS)

Asbah, Nedaa

2016-09-01

The trigger system of the ATLAS experiment is designed to reduce the event rate from the LHC nominal bunch crossing at 40 MHz to about 1 kHz, at the design luminosity of 1034 cm-2 s-1. After a successful period of data taking from 2010 to early 2013, the LHC already started with much higher instantaneous luminosity. This will increase the load on High Level Trigger system, the second stage of the selection based on software algorithms. More sophisticated algorithms will be needed to achieve higher background rejection while maintaining good efficiency for interesting physics signals. The Fast TracKer (FTK) is part of the ATLAS trigger upgrade project. It is a hardware processor that will provide, at every Level-1 accepted event (100 kHz) and within 100 microseconds, full tracking information for tracks with momentum as low as 1 GeV. Providing fast, extensive access to tracking information, with resolution comparable to the offline reconstruction, FTK will help in precise detection of the primary and secondary vertices to ensure robust selections and improve the trigger performance. FTK exploits hardware technologies with massive parallelism, combining Associative Memory ASICs, FPGAs and high-speed communication links.

Formation, stability and dissociation dynamics of {{\\rm{N}}}_{2}{}^{{\\rm{n}}+} cations (n = 1 - 2) in 3.5 keV e - -N2 collisions studied using the energy resolved electron-ion coincidence technique

NASA Astrophysics Data System (ADS)

Kumar, S.; Prajapati, S.; Singh, B.; Singh, B. K.; Shanker, R.

2018-04-01

Coincidences between energy selected electrons and ions produced in the decay of a core hole ionized (excited) state in a free nitrogen molecule have been measured at three specified energies of emitted electrons to reveal the individual pathways produced in 3.5 keV electron-induced fragmentation processes. From these measurements, it has been possible to show, for the first time, that in addition to the normal Auger decay, the resonant Auger excitation channels also share their appreciable contributions in producing singly charged parent ions in an electron-induced collision system. The correlations between ion fragmentation products and electronic structures with a hole configuration in singly-, doubly- and possibly in triply charged molecular electronic states populated in the electronic decay of the initial core hole have been studied and discussed. KER values obtained from our experiments are found to be consistent with the previous results of photo absorption experiments for fragmentation channel {{{{N}}}2}2+ → N+ + N+ however, N2+ fragment ions are found to arise mainly from the fragmentation channel {{{{N}}}2}2+ → N2+ + N and to possess relatively low kinetic energies in the considered region of binding energies.

Social aesthetics and the management of addiction.

PubMed

Musalek, Michael

2010-11-01

One of the main causes of nonadherence is that the goals and forms of addiction treatment are not sufficiently attractive. To study the attractiveness of treatment in clinical practice inevitably means to enter the field of social aesthetics. The call for the implementation of social aesthetics in practice results in a shift of paradigms in the treatment of patients suffering from dependence syndromes. The main themes in the literature covered by the article focus on the role of social aesthetics in medicine in general, as well as on the attractiveness of addiction treatment, in particular. When treatment objectives and programmes become more attractive the result will be reduced drop-out rates, and in turn an increase of treatment effectiveness. Transferring theory of social aesthetics to clinical practice, the Anton Proksch Institute's Orpheus Programme is concerned with opening up spaces and creating atmospheres in which it becomes possible for the individual addicts to realise their possibilities. The challenge in the therapeutic process is not only to recognise the significance of the disorders' pathology but also to find ways out of the imagined impossibilities by opening up new possibilities and uncovering resources of the suffering human.

The astrological roots of mesmerism.

PubMed

Schaffer, Simon

2010-06-01

Franz Anton Mesmer's 1766 thesis on the influence of the planets on the human body, in which he first publicly presented his account of the harmonic forces at work in the microcosm, was substantially copied from the London physician Richard Mead's early eighteenth century tract on solar and lunar effects on the body. The relation between the two texts poses intriguing problems for the historiography of medical astrology: Mesmer's use of Mead has been taken as a sign of the Vienna physician's enlightened modernity while Mead's use of astro-meteorology has been seen as evidence of the survival of antiquated astral medicine in the eighteenth century. Two aspects of this problem are discussed. First, French critics of mesmerism in the 1780s found precedents for animal magnetism in the work of Paracelsus, Fludd and other early modern writers; in so doing, they began to develop a sophisticated history for astrology and astro-meteorology. Second, the close relations between astro-meteorology and Mead's project illustrate how the environmental medical programmes emerged. The making of a history for astrology accompanied the construction of various models of the relation between occult knowledge and its contexts in the enlightenment.

History of Neurosurgery in Palestine.

PubMed

Darwazeh, Rami; Darwazeh, Mazhar; Sun, Xiaochuan

2017-08-01

Palestinian neurosurgery started with Dr. Antone Tarazi as the first Palestinian neurosurgeon. Before that, there was no organized neurosurgery specialty, and general surgeons performed neurosurgical procedures. Here we review the history of neurosurgery and neurosurgical applications in Palestine, evaluate some limitations of the current system, and discuss major challenges to improving this system. We collected information from various sources in either English or Arabic. The development of neurosurgery and neurosurgical training in Palestine began in 1960 with the first center established in Jerusalem, which provided much-needed neurosurgical services and training in the fields of neurosurgery and neurology. Palestine has produced a number of its own neurosurgeons and has promoted further progress by establishing the Palestinian Neurosurgical Society in 2014. Today, there are 34 neurosurgeons (including 1 female neurosurgeon) and 17 residents providing expert care in 17 centers across Palestine, along with 1 neurosurgical residency program. Neurosurgery in Palestine has faced many challenges, some of which have been overcome. However, there remain many challenges, which will require much time and effort to surmount. Political stabilization is a significant factor in the progress of neurosurgery in Palestine. Copyright © 2017 Elsevier Inc. All rights reserved.

Accelerated molecular dynamics simulations of protein folding.

PubMed

Miao, Yinglong; Feixas, Ferran; Eun, Changsun; McCammon, J Andrew

2015-07-30

Folding of four fast-folding proteins, including chignolin, Trp-cage, villin headpiece and WW domain, was simulated via accelerated molecular dynamics (aMD). In comparison with hundred-of-microsecond timescale conventional molecular dynamics (cMD) simulations performed on the Anton supercomputer, aMD captured complete folding of the four proteins in significantly shorter simulation time. The folded protein conformations were found within 0.2-2.1 Å of the native NMR or X-ray crystal structures. Free energy profiles calculated through improved reweighting of the aMD simulations using cumulant expansion to the second-order are in good agreement with those obtained from cMD simulations. This allows us to identify distinct conformational states (e.g., unfolded and intermediate) other than the native structure and the protein folding energy barriers. Detailed analysis of protein secondary structures and local key residue interactions provided important insights into the protein folding pathways. Furthermore, the selections of force fields and aMD simulation parameters are discussed in detail. Our work shows usefulness and accuracy of aMD in studying protein folding, providing basic references in using aMD in future protein-folding studies. © 2015 Wiley Periodicals, Inc.

ZOONET: perspectives on the evolution of animal form. Meeting report.

PubMed

Fischer, Antje H L; Arboleda, Enrique; Egger, Bernhard; Hilbrant, Maarten; McGregor, Alistair P; Cole, Alison G; Daley, Allison C

2009-11-15

What drives evolution? This was one of the main questions raised at the final ZOONET meeting in Budapest, Hungary, in November 2008. The meeting marked the conclusion of ZOONET, an EU-funded Marie-Curie Research Training Network comprising nine research groups from all over Europe (Max Telford, University College London; Michael Akam, University of Cambridge; Detlev Arendt, EMBL Heidelberg; Maria Ina Arnone, Stazione Zoologica Anton Dohrn Napoli; Michalis Averof, IMBB Heraklion; Graham Budd, Uppsala University; Richard Copley, University of Oxford; Wim Damen, University of Cologne; Ernst Wimmer, University of Göttingen). ZOONET meetings and practical courses held during the past four years provided researchers from diverse backgrounds--bioinformatics, phylogenetics, embryology, palaeontology, and developmental and molecular biology--the opportunity to discuss their work under a common umbrella of evolutionary developmental biology (Evo Devo). The Budapest meeting emphasized in-depth discussions of the key concepts defining Evo Devo, and bringing together ZOONET researchers with external speakers who were invited to present their views on the evolution of animal form. The discussion sessions addressed four main topics: the driving forces of evolution, segmentation, fossils and phylogeny, and the future of Evo Devo.

Microwave Irradiation on Graphene Dispersed Within Polymeric Matrices

NASA Astrophysics Data System (ADS)

Cisneros, Jorge; Yust, Brian; Chipara, Mircea

Graphene is a two dimensional nanomaterial with high thermal and electric conductivity and Young modulus. These features make graphene an ideal reinforcement for polymeric matrices. However, the mechanical features of polymer-carbon nanostructured composites are limited by the dispersion of the filler and by the delamination or microcracks initiated at the interface between the polymeric matrix and nanofiller. This last weakness can be addressed by improving the interface via chemical and physical methods. Microwave heating of graphite is a very efficient approach if the polymeric matrix does not also have a strong absorption. During the irradiation, the nanofiller is preferentially heated; the local melting of the polymer at the interface improves the interface by filling the microcracks and delaminations. Nanocomposites of polystyrene-poly(ethylene-ran-butylene)-polystyrene loaded by various amounts of graphene ranging from 0 % to 20 % wt. have been prepared by solution mixing using chloroform as solvent. The as obtained nanocomposites have been subjected to microwave irradiation in an Anton Paar Monowave 300 system operating at 75 W, for various irradiation times 5, 10, 15, 30, 45, and 60 minutes. The effect of microwave irradiation has been studied by Raman spectroscopy.

A Compendium of Volatile Organic Compounds (VOCs) Released By Human Cell Lines

PubMed Central

Filipiak, Wojciech; Mochalski, Pawel; Filipiak, Anna; Ager, Clemens; Cumeras, Raquel; Davis, Cristina E.; Agapiou, Agapios; Unterkofler, Karl; Troppmair, Jakob

2016-01-01

Volatile organic compounds (VOCs) offer unique insights into ongoing biochemical processes in healthy and diseased humans. Yet, their diagnostic use is hampered by the limited understanding of their biochemical or cellular origin and their frequently unclear link to the underlying diseases. Major advancements are expected from the analyses of human primary cells, cell lines and cultures of microorganisms. In this review, a database of 125 reliably identified VOCs previously reported for human healthy and diseased cells was assembled and their potential origin is discussed. The majority of them have also been observed in studies with other human matrices (breath, urine, saliva, feces, blood, skin emanations). Moreover, continuing improvements of qualitative and quantitative analyses, based on the recommendations of the ISO-11843 guidelines, are suggested for the necessary standardization of analytical procedures and better comparability of results. The data provided contribute to arriving at a more complete human volatilome and suggest potential volatile biomarkers for future validation. Dedication: This review is dedicated to the memory of Prof. Dr. Anton Amann, who sadly passed away on January 6, 2015. He was motivator and motor for the field of breath research. PMID:27160536

Adverse Outcome Pathways – Organizing Toxicological ...

EPA Pesticide Factsheets

The number of chemicals for which environmental regulatory decisions are required far exceeds the current capacity for toxicity testing. High throughput screening (HTS) commonly used for drug discovery has the potential to increase this capacity. The adverse outcome pathway (AOP) concept has emerged as a natural framework for connecting high throughput toxicity testing (HTT) results to potential impacts on humans and wildlife populations. An AOP consists of two main components that describe the biological mechanisms driving toxicity. Key events represent biological processes essential for causing the adverse outcome that are also measurable experimentally. Key event relationships capture the biological processes connecting the key events. Evidence documented for each KER based on measurements of the KEs can provide the confidence needed for extrapolating HTT from early key events to overt toxicity represented by later key events based on the AOP. The IPCS mode of action (MOA) framework incorporates information required for making a chemical-specific toxicity determination. Given the close relationship between the AOP and MOA frameworks, it is possible to assemble an MOA by incorporating HTT results, chemical properties including absorption, distribution, metabolism, and excretion (ADME), and an AOP describing the biological basis of toxicity thereby streamlining the process. While current applications focus on the assessment of risk for environmental chemicals,

Developing the concept of sustainability in nursing.

PubMed

Goodman, Benny

2016-10-01

Sustainability, and the related concept of climate change, is an emerging domain within nursing and nurse education. Climate change has been posited as a serious global health threat requiring action by health professionals and action at international level. Anåker & Elf undertook a concept analysis of sustainability in nursing based on Walker and Avant's framework. Their main conclusions seem to be that while defining attributes and cases can be established, there is not enough research into sustainability in the nursing literature. This paper seeks to develop their argument to argue that sustainability in nursing can be better understood by accessing non-nursing and grey literature and, for example, the literature in the developing web-based 'paraversity'. Without this understanding, and application in nursing scholarship, nurses will have a rather narrow understanding of sustainability and its suggested links with social and health inequalities and the dynamics underpinning unsustainable neoliberalist political economy. This understanding is based on the social and political determinants of health approach and the emerging domain of planetary health. However, this is a major challenge as it requires a critical reflection on what counts as nursing knowledge, a reflection which might reject sustainability and political economy as irrelevant to much of nursing practice. © 2016 John Wiley & Sons Ltd.

Peer review statement

NASA Astrophysics Data System (ADS)

2010-08-01

All papers published in this Volume 12 of IOP Conference Series: Earth and Environmental Science have been peer reviewed through processes administered by the editors of the 25th IAHR Symposium on Hydraulic Machinery and Systems proceedings, Professor Romeo Susan-Resiga, Dr Sebastian Muntean and Dr Sandor Bernad. Reviews were conducted by expert referees from the Scientific Committee to the professional and scientific standards expected of a proceedings journal published by IOP Publishing. The members of the Scientific Committee who selected and reviewed the papers included in the Proceedings of the 25th IAHR Symposium on Hydraulic Machinery and Systems are: Anton ANTONTechnical University of Civil Engineering, BucharestRomania François AVELLANEcole Polytechnique Fédérale de LausanneSwitzerland Fidel ARZOLAEDELCAVenezuela Thomas ASCHENBRENNERVoith Hydro Gmb H & Co. KG, HeidenheimGermany Anton BERGANTLitostroj Power d.o.o., LjubljanaSlovenia Gerard BOISENSAM, LilleFrance Hermod BREKKENTNU, TrondheimNorway Stuart COULSON Voith Hydro Inc., YorkUSA Eduard EGUSQUIZAPolytechnical University Catalonia BarcelonaSpain Arpad FAYUniversity of MiskolczHungary Richard FISHERVoith Hydro Inc., York USA Regiane FORTES-PATELLAInstitut Polytechnique de GrenobleFrance Aleksandar GAJICUniversity of BelgradeSerbia Arno GEHRERAndritz Hydro GrazAustria José GONZÁLEZUniversidad de OviedoSpain François GUIBAULTEcole Polytechnique de MontrealCanada Chisachi KATOUniversity of TokyoJapan Kwang-Yong KIMInha University, IncheonKorea Jiri KOUTNIKVoith Hydro Gmb H & Co. KG, HeidenheimGermany Adrian LUNGUDunarea de Jos University of GalatiRomania Christophe NICOLETPower Vision Engineering Sàrl, LausanneSwitzerland Torbjøm K. NIELSENNTNU, TrodheimNorway Michihiro NISHIKyushu Institute of TechnologyJapan Maryse PAGEHydro Quebec IREQ, VarennesCanada Etienne PARKINSONAndritz Hydro LtdSwitzerland František POCHYLYBrno UniversityCzech Republic Stefan RIEDELBAUCHVoith Hydro Gmb H & Co. KG

The Hybrid Expert in the "Bergstaat": Anton Von Ruprecht as a Professor of Chemistry and Mining and as a Mining Official, 1779-1814

ERIC Educational Resources Information Center

Konecny, Peter

2012-01-01

In the course of the 18th century a new type of scientifically educated functional elites developed, who were trained to administer mines. The educational project that led to the formation of a corps of mining engineers was part of a programme of administrative and economic reforms that led to a new configuration of bonds between state, economy…

Prediction, Refinement and Persistency of Transmembrane Helix Dimers in Lipid Bilayers using Implicit and Explicit Solvent/Lipid Representations: Microsecond Molecular Dynamics Simulations of ErbB1/B2 and EphA1

PubMed Central

Zhang, Liqun; Sodt, Alexander J.; Venable, Richard M.; Pastor, Richard W.; Buck, Matthias

2012-01-01

All-atom simulations are carried out on ErbB1/B2 and EphA1 transmembrane helix dimers in lipid bilayers starting from their solution/DMPC bicelle NMR structures. Over the course of microsecond trajectories, the structures remain in close proximity to the initial configuration and satisfy the great majority of experimental tertiary contact restraints. These results further validate CHARMM protein/lipid force fields and simulation protocols on Anton. Separately, dimer conformations are generated using replica exchange in conjunction with an implicit solvent and lipid representation. The implicit model requires further improvement, and this study investigates whether lengthy all-atom molecular dynamics simulations can alleviate the shortcomings of the initial conditions. The simulations correct many of the deficiencies. For example excessive helix twisting is eliminated over a period of hundreds of nanoseconds. The helix tilt, crossing angles and dimer contacts approximate those of the NMR derived structure, although the detailed contact surface remains off-set for one of two helices in both systems. Hence, even microsecond simulations are not long enough for extensive helix rotations. The alternate structures can be rationalized with reference to interaction motifs and may represent still sought after receptor states that are important in ErbB1/B2 and EphA1 signaling. PMID:23042146

Dancing with chemical formulae of antivirals: A panoramic view (Part 2).

PubMed

De Clercq, Erik

2013-11-15

In this second part of "Dancing with antivirals as chemical formulae" I will focus on a number of chemical compounds that in the last few years have elicited more than common attraction from a commercial viewpoint: (i) favipiravir (T-705), as it is active against influenza, but also several other RNA viruses; (ii) neuraminidase inhibitors such as zanamivir and oseltamivir; (iii) peramivir and laninamivir octanoate, which might be effective against influenza virus following a single (intravenous or inhalation) administration; (iv) sofosbuvir, the (anticipated) cornerstone for the interferon-free therapy of HCV infections; (v) combinations of DAAs (direct antiviral agents) to achieve, in no time, a sustained virus response (SVR) against HCV infection; (vi) HIV protease inhibitors, the latest and most promising being darunavir; (vii) the integrase inhibitors (INIs) (raltegravir, elvitegravir, dolutegravir), representing a new dimension in the anti-HIV armamentarium; (viii), a new class of helicase primase inhibitors (HPIs) that may exceed acyclovir and the other anti-herpes compounds in both potency and safety; (ix) CMX-001, as the latest of Dr. Antonín Holý's legacy for its activity against poxviruses and CMV infections, and (x) noroviruses for which the ideal antiviral compounds are still awaited for. Copyright © 2013 Elsevier Inc. All rights reserved.

[The First School of Vienna and Samuel Hahnemann's pharmaceutical techniques].

PubMed

Gantenbein, U L

2000-01-01

The First or Elder Vienna School of Medicine was initiated by Gerard van Swieten, the famous pupil of Herman Boerhaave. The aim of this school was to put medicine on new scientific foundations-promoting unprejudiced clinical observation, botanical and chemical research, and the introduction of simple but powerful remedies. One of the products of this school was Anton Störck (1731-1803), appointed Director of Austrian public health and medical education by Empress Maria Theresia. Following the tradition of the Vienna School, Störck was the first scientist to systematically test the effects of so-called poisonous plants (e.g., hemlock, henbane, meadow saffron). Discovering new therapeutic properties in previously dreaded plants, Störck used himself as a subject in experiments to determine tolerable dose levels. As a result of his investigations, Störck was able to successfully treat his patients using the drugs he discovered. Samuel Hahnemann's later writings, including his "Organon", show that he was considerably influenced by Störck's ideas. In fact, Hahnemann's clinical teacher at Vienna was a follower of Störck, Joseph Quarin. Hahnemann's elaborate system of validating homeopath material can be seen as a development and refinement of the techniques he learned in Vienna.

Rheological Properties of Automorphic and Semihydromorphic Cryometamorphic Northern Taiga Soils in Northeastern European Russia (Komi Republic)

NASA Astrophysics Data System (ADS)

Kholopov, Yu. V.; Khaidapova, D. D.; Lapteva, E. M.

2018-04-01

Soil pastes at the water content corresponding to the maximum swelling of samples from different genetic horizons of cryometamorphic soils―surface-gleyic iron-illuvial svetlozem (Folic Albic Stagnosol) and peaty and peat humus-impregnated gleyic svetlozems (Histic Gleyic Stagnosols)―have been studied with an MCR-302 modular rheometer (Anton Paar, Austria). It has been found that the strongest interparticle bonds are formed in the horizons of cryometamorphic soils characterized by high contents of humic substances and organomineral Al-Fe-humus compounds. These are horizons of podzol microprofile (Eg and BHF) in iron-illuvial svetlozem and a humus-impregnated horizon (ELhi,g) in peaty and peat svetlozems. Organomineral Al-Fe-humus compounds, as well as the seasonal freezing of soils, determine the elastic-brittle character of interparticle interactions. The contents of clay fractions, exchangeable bases, and organic and organomineral substances impart viscoelastic properties to these contacts. An enhancement of elastic-brittle properties of soil is observed under the impact of gleying and freezing. The threefold decrease of the structural interaction parameter (∫ Z) when going from automorphic to semihydromorphic conditions indicates a decrease in the resistance of peaty and peat svetlozems to mechanical loads under increasing hydromorphism compared to iron-illuvial svetlozems.

Long-timescale molecular dynamics simulations elucidate the dynamics and kinetics of exposure of the hydrophobic patch in troponin C.

PubMed

Lindert, Steffen; Kekenes-Huskey, Peter M; McCammon, J Andrew

2012-10-17

Troponin (Tn) is an important regulatory protein in the thin-filament complex of cardiomyocytes. Calcium binding to the troponin C (TnC) subunit causes a change in its dynamics that leads to the transient opening of a hydrophobic patch on TnC's surface, to which a helix of another subunit, troponin I (TnI), binds. This process initiates contraction, making it an important target for studies investigating the detailed molecular processes that underlie contraction. Here we use microsecond-timescale Anton molecular dynamics simulations to investigate the dynamics and kinetics of the opening transition of the TnC hydrophobic patch. Free-energy differences for opening are calculated for wild-type Ca(2+)-bound TnC (∼8 kcal/mol), V44Q Ca(2+)-bound TnC (3.2 kcal/mol), E40A Ca(2+)-bound TnC (∼12 kcal/mol), and wild-type apo TnC (∼20 kcal/mol). These results suggest that the mutations have a profound impact on the frequency with which the hydrophobic patch presents to TnI. In addition, these simulations corroborate that cardiac wild-type TnC does not open on timescales relevant to contraction without calcium being bound. Copyright © 2012 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Three-Dimensional Dynamics of Baroclinic Tides Over a Seamount

NASA Astrophysics Data System (ADS)

Vlasenko, Vasiliy; Stashchuk, Nataliya; Nimmo-Smith, W. Alex M.

2018-02-01

The Massachusetts Institute of Technology general circulation model is used for the analysis of baroclinic tides over Anton Dohrn Seamount (ADS), in the North Atlantic. The model output is validated against in situ data collected during the 136th cruise of the RRS "James Cook" in May-June 2016. The observational data set includes velocity time series recorded at two moorings as well as temperature, salinity, and velocity profiles collected at 22 hydrological stations. Synthesis of observational and model data enabled the reconstruction of the details of baroclinic tidal dynamics over ADS. It was found that the baroclinic tidal waves are generated in the form of tidal beams radiating from the ADS periphery to its center, focusing tidal energy in a surface layer over the seamount's summit. This energy focusing enhances subsurface water mixing and the local generation of internal waves. The tidal beams interacting with the seasonal pycnocline generate short-scale internal waves radiating from the ADS center. An important ecological outcome from this study concerns the pattern of residual currents generated by tides. The rectified flows over ADS have the form of a pair of dipoles, cyclonic and anticyclonic eddies located at the seamount's periphery. These eddies are potentially an important factor in local larvae dispersion and their escape from ADS.

Rheological Properties of Nanoparticle Silica-Surfactant Stabilized Crude Oil Emulsions: Influence of Temperature, Nanoparticle Concentration and Water Volume Fraction"

NASA Astrophysics Data System (ADS)

Kinsey, Erin; Pales, Ashley; Li, Chunyan; Mu, Linlin; Bai, Lingyun; Clifford, Heather; Darnault, Christophe

2016-04-01

Oil in water emulsions occur during oil extraction due to the presence of water, naturally-occurring surface-active agents and mechanical mixing in pipelines or from oil spillage. Emulsions present difficulties for use of oil in fuel and their rheological properties are important to treat environmental impacts of spills. The objective of this study is to assess the rheological characteristics of oil in water emulsions stabilized by 5% NaCl brine, Tween 20 surfactant and silica nanoparticles to gain knowledge about the behavior of oil flow in pipelines and characterize them for environmental applications. Rheological behaviors such as shear rate, shear stress, and viscosity of Prudhoe Bay crude oil emulsions were analyzed with varying percent of water volume fractions (12.5, 25 and 50%), varying weight percent of silica nanoparticles (0.001, 0.01 and 0.1 weight %), with and without 2 CMC Tween 20 nonionic surfactant. Emulsions with varying water volume fractions were analyzed at 20, 40 and 60 degrees Celsius. Flow curve analysis of the emulsions was performed using an Anton-Paar rheometer. Preliminary findings indicate that increased temperature and increasing the concentration of nanoparticles both produced lower shear stress and that the addition of surfactant decreased the viscosity and shear stress of the emulsions.

Detection of biological threats. A challenge for directed molecular evolution.

PubMed

Petrenko, Valery A; Sorokulova, Iryna B

2004-08-01

The probe technique originated from early attempts of Anton van Leeuwenhoek to contrast microorganisms under the microscope using plant juices, successful staining of tubercle bacilli with synthetic dyes by Paul Ehrlich and discovery of a stain for differentiation of gram-positive and gram-negative bacteria by Hans Christian Gram. The technique relies on the principle that pathogens have unique structural features, which can be recognized by specifically labeled organic molecules. A hundred years of extensive screening efforts led to discovery of a limited assortment of organic probes that are used for identification and differentiation of bacteria. A new challenge--continuous monitoring of biological threats--requires long lasting molecular probes capable of tight specific binding of pathogens in unfavorable conditions. To respond to the challenge, probe technology is being revolutionized by utilizing methods of combinatorial chemistry, phage display and directed molecular evolution. This review describes how molecular evolution methods are applied for development of peptide, antibody and phage probes, and summarizes the author's own data on development of landscape phage probes against Salmonella typhimurium. The performance of the probes in detection of Salmonella is illustrated by a precipitation test, enzyme-linked immunosorbent assay (ELISA), fluorescence-activated cell sorting (FACS) and fluorescent, optical and electron microscopy.

Multiphoton Rydberg and valence dynamics of CH3Br probed by mass spectrometry and slice imaging.

PubMed

Hafliðason, Arnar; Glodic, Pavle; Koumarianou, Greta; Samartzis, Peter C; Kvaran, Ágúst

2018-06-18

The multiphoton dynamics of CH3Br were probed by Mass Resolved MultiPhoton Ionization (MR-MPI), Slice Imaging and Photoelectron Imaging in the two-photon excitation region of 66 000 to 80 000 cm-1. Slice images of the CH3+ and Br+ photoproducts of ten two-photon resonant transitions to np and nd Rydberg states of the parent molecule were recorded. CH3+ ions dominate the mass spectra. Kinetic energy release spectra (KERs) were derived from slice and photoelectron images and anisotropy parameters were extracted from the angular distributions of the ions to identify the processes and the dynamics involved. At all wavelengths we observe three-photon excitations, via the two-photon resonant transitions to molecular Rydberg states, forming metastable, superexcited (CH3Br#) states which dissociate to form CH3 Rydberg states (CH3**) along with Br/Br*. A correlation between the parent Rydberg states excited and CH3** formed is evident. For the three highest excitation energies used, the CH3Br# metastable states also generate high kinetic energy fragments of CH3(X) and Br/Br*. In addition for two out of these three wavelengths we also measure one-photon photolysis of CH3Br in the A band forming CH3(X) in various vibrational modes and bromine atoms in the ground (Br) and spin-orbit excited (Br*) states.

Adverse Outcome Pathway (AOP) Network Development for ...

EPA Pesticide Factsheets

Adverse outcome pathways (AOPs) are descriptive biological sequences that start from a molecular initiating event (MIE) and end with an adverse health outcome. AOPs provide biological context for high throughput chemical testing and further prioritize environmental health risk research. According to the Organization for Economic Co-operation and Development guidelines, AOPs are pathways with one MIE anchored to an adverse outcome (AO) by key events (KEs) and key event relationships (KERs). However, this approach does not always capture the cumulative impacts of multiple MIEs on the AO. For example, hepatic lipid flux due to chemical-induced toxicity initiates from multiple ligand-activated receptors and signaling pathways that cascade across biology to converge upon a common fatty liver (FL, also known as steatosis) outcome. To capture this complexity, a top-down strategy was used to develop a FL AOP network (AOPnet). Literature was queried based on the terms steatosis, fatty liver, cirrhosis, and hepatocellular carcinoma. Search results were analyzed for physiological and pathophysiological organ level, cellular and molecular processes, as well as pathway intermediates, to identify potential KEs and MIEs that are key for hepatic lipid metabolism, maintenance, and dysregulation. The analysis identified four apical KE nodes (hepatic fatty acid uptake, de novo fatty acid and lipid synthesis, fatty acid oxidation, and lipid efflux) juxtaposed to the FL AO. The apic

Anti-inflammatory activities of Ophiopogonis Radix on hydrogen peroxide-induced cellular senescence of normal human dermal fibroblasts.

PubMed

Kitahiro, Yumi; Koike, Atsushi; Sonoki, Aska; Muto, Mei; Ozaki, Kazuo; Shibano, Makio

2018-06-30

Ophiopogonis Radix (Ophiopogon root), which nourishes the yin, has been used in clinical practice to promote fluid secretion and to moisturize the lungs and skin in traditional Chinese and Japanese (Kampo) medicine. To evaluate this traditional medicinal effect, we investigated the anti-chronic inflammatory effect of Radix Ophiopogonis on senescent cells. Conversely, although several phenotypes of Ophiopogon japonicus Ker-Gawler (Liliaceae) are prevalent in Japan and China, we used these Ophiopogon roots by considering them as one crude drug, Ophiopogonis Radix. In this study, it was revealed that there are two chemotypes (Types A and B) in the root of the original plant, O. japonicus. Methylophiopogonanone A (compound 1) and methylophiopogonanone B (compound 2) were isolated as index compounds from Type A and compound 1 and ophiopogonanone A (compound 3) from Type B. In addition, ophiopogonin B (compound 4) was isolated as the main steroidal saponin from both Type A and B. The results indicated that two different methanol extracts (from Types A and B) and the main constituents of O. japonicus (compound 1-4), significantly downregulated the expression of interleukin (IL)-6 and IL-8, which were enhanced by senescent normal human dermal fibroblasts. Moreover, the two different methanol extracts and compounds 1-4 decreased IL-6 production in a strong and concentration-dependent manner by the ELISA method.

A conceptual framework to support exposure science research ...

EPA Pesticide Factsheets

While knowledge of exposure is fundamental to assessing and mitigating risks, exposure information has been costly and difficult to generate. Driven by major scientific advances in analytical methods, biomonitoring, computational tools, and a newly articulated vision for a greater impact in public health, the field of exposure science is undergoing a rapid transition that allows it to be more agile, predictive, and data- and knowledge-driven. A necessary element of this evolved paradigm is an organizational and predictive framework for exposure science that furthers the application of systems-based approaches. To enable such systems-based approaches, we proposed the Aggregate Exposure Pathway (AEP) concept to organize data and information emerging from an invigorated and expanding field of exposure science. The AEP framework is a layered structure that describes the elements of an exposure pathway, as well as the relationship between those elements. The basic building blocks of an AEP adopt the naming conventions used for Adverse Outcome Pathways (AOPs): Key Events (KEs) to describe the measurable, obligate steps through the AEP; and Key Event Relationships (KERs) describe the linkages between KEs. Importantly, the AEP offers an intuitive approach to organize exposure information from sources to internal site of action, setting the stage for predicting stressor concentrations at an internal target site. These predicted concentrations can help inform the r

[Oswald Schwarz: a pioneer in psychosomatic urology and sexual medicine].

PubMed

Berberich, H J; Schultheiss, D; Kieser, B

2015-01-01

Oswald Schwarz, a urologist from Vienna, was a scholar of Anton Ritter von Frisch and Hans Rubritius. As a physician during World War I, he was confronted with numerous bullet wounds to the spinal cord. In 1919, he completed his professorial thesis"Bladder dysfunction as a result of bullet wounds to the spinal cord". Oswald Schwarz was known as a committed surgeon. As an urologist he also treated patients with sexual dysfunction. Besides his practical and scientific urology-related work, he was also interested in psychology and philosophy. He held lectures on both subjects earning himself the nickname, the Urosoph. In the 1920s, Oswald Schwarz belonged to the inner circle of Alfred Adler, the founder of Individual Psychology, and was editor of the first psychosomatic textbook published in German, "Psychological origin and psychotherapy of physical symptoms" (1925). In addition, Schwarz wrote numerous articles and several books on sexual medicine. He also made many valuable contributions to the development of medical anthropology. Altogether, his work includes over 130 publications. Faced with the rise of fascism and National Socialism in Europe, Oswald Schwarz, who was of Jewish origin, emigrated to England in 1934. There he died in 1949. Unfortunately his scientific work has largely been forgotten. The aim of the following article is to remind us of his important contributions to the field.

AIDS and Africa. Introduction.

PubMed

Kopelman, Loretta M; van Niekerk, Anton A

2002-04-01

Sub-Saharan Africa is the epicenter of the HIV/AIDS epidemic, and in this issue of the Journal, seven authors discuss the moral, social and medical implications of having 70% of those stricken living in this area. Anton A. van Niekerk considers complexities of plague in this region (poverty, denial, poor leadership, illiteracy, women's vulnerability, and disenchantment of intimacy) and the importance of finding responses that empower its people. Solomon Benatar reinforces these issues, but also discusses the role of global politics in sub-Saharan Africa, especially discrimination, imperialism and its exploitation by first world countries. Given the public health crisis, Udo Schüklenk and Richard E. Ashcroft defend compulsory licensing of essential HIV/AIDS medications on consequentialist grounds. Keymanthri Moodley discusses the importance of conducting research and the need to understand a moderate form of communitarianism, also referred to as "ubuntu" or "communalism", to help some Africans understand research as an altruistic endeavour. Godfrey B. Tangwa also defends traditional African values of empathy and ubuntu, discussing how they should be enlisted to fight this pandemic. Loretta M. Kopelman criticizes the tendency among those outside Africa to dismiss the HIV/AIDS pandemic, attributing one source to the ubiquitous and misguided punishment theory of disease. The authors conclude that good solutions must be cooperative ventures among countries within and outside of sub-Saharan Africa with far more support from wealthy countries.

Utilizing the "Plan, Do, Study, Act" Framework to Explore the Process of Curricular Assessment and Redesign in a Physical Therapy Education Program in Suriname.

PubMed

Audette, Jennifer Gail; Baldew, Se-Sergio; Chang, Tony C M S; de Vries, Jessica; Ho A Tham, Nancy; Janssen, Johanna; Vyt, Andre

2017-01-01

To describe how a multinational team worked together to transition a physical therapy (PT) educational program in Paramaribo, Suriname, from a Bachelor level to a Master of Science in Physical Therapy (MSPT) level. The team was made up of PT faculty from Anton De Kom Universiteit van Suriname (AdeKUS), the Flemish Interuniversity Council University Development Cooperation (VLIR-UOS) leadership, and Health Volunteers Overseas volunteers. In this case study, the process for curricular assessment, redesign, and upgrade is described retrospectively using a Plan, Do, Study, Act (PDSA) framework. PT educational programs in developing countries are eager for upgrade to meet international expectations and to better meet community health-care needs. An ongoing process which included baseline assessment of all aspects of the existing bachelor's program in PT, development of a plan for a MSPT, implementation of the master's program, and evaluation following implementation is described. Curricular assessment and upgrade in resource-limited countries requires the implementation of process-oriented methods. The PDSA process is a useful tool to explore curricular development. The international collaboration described in this paper provides an example of the diligence, consistency, and dedication required to see a project through and achieve success while providing adequate support to the host site. This project might provide valuable insights for those involved in curricular redesign in similar settings.

Rheological Characterization and Cluster Classification of Iranian Commercial Foods, Drinks and Desserts to Recommend for Esophageal Dysphagia Diets.

PubMed

Zargaraan, Azizollaah; Omaraee, Yasaman; Rastmanesh, Reza; Taheri, Negin; Fadavi, Ghasem; Fadaei, Morteza; Mohammadifar, Mohammad Amin

2013-12-01

In the absence of dysphagia-oriented food products, rheological characterization of available food items is of importance for safe swallowing and adequate nutrient intake of dysphagic patients. In this way, introducing alternative items (with similar ease of swallow) is helpful to improve quality of life and nutritional intake of esophageal cancer dysphagia patients. The present study aimed at rheological characterization and cluster classification of potentially suitable foodstuffs marketed in Iran for their possible use in dysphagia diets. In this descriptive study, rheological data were obtained during January and February 2012 in Rheology Lab of National Nutrition and Food Technology Research Institute Tehran, Iran. Steady state and oscillatory shear parameters of 39 commercial samples were obtained using a Physica MCR 301 rheometer (Anton-Paar, GmbH, Graz, Austria). Matlab Fuzzy Logic Toolbox (R2012 a) was utilized for cluster classification of the samples. Using an extended list of rheological parameters and fuzzy logic methods, 39 commercial samples (drinks, main courses and desserts) were divided to 5 clusters and degree of membership to each cluster was stated by a number between 0 and 0.99. Considering apparent viscosity of foodstuffs as a single criterion for classification of dysphagia-oriented food products is shortcoming of current guidelines in dysphagia diets. Authors proposed to some revisions in classification of dysphagia-oriented food products and including more rheological parameters (especially, viscoelastic parameters) in the classification.

Sperm Parameters: Paradigmatic Index of Good Health and Longevity

PubMed Central

Omu, Alexander E.

2013-01-01

Since the discovery of spermatozoon by Anton van Leeuwenhoek in 1677, there has been an ever increasing understanding of its role in reproduction. Many factors adversely affect sperm quality, including varicocele, accessory gland infection, immunological factors, congenital abnormalities, and iatrogenic systemic and endocrine causes, such as diabetes mellitus, obesity, metabolic syndrome, and smoking. The mechanisms responsible for the association between poor sperm parameters and ill health may include oxidative stress, low-grade inflammation, low testosterone, and low sex-hormone-binding globulin. Oxidative stress in the testicular microenvironment may result in decreased spermatogenesis and sperm DNA damage, loss of sperm motility, and abnormal sperm morphology. Low testosterone caused by advanced age, visceral obesity, and inflammation is associated with the development of cardiovascular disease. Hence, semen analysis has an important role in the routine evaluation of idiopathic male infertility, usually manifested as low sperm counts, impaired sperm motility, or absence of sperm, and remains the most common single diagnostic tool. Several studies have shown an inverse relationship between semen quality and medical disorders. This review elucidates the effect of medical disorders and social habits on sperm quality, the mechanisms that are involved in the impairment of sperm quality, and whether or not sperm quality can be used as an index of good health and longevity in a man. PMID:24051979

The Core Pattern Analysis on Chinese Herbal Medicine for Sjögren's syndrome: A Nationwide Population-Based Study

PubMed Central

Chang, Ching-Mao; Chu, Hsueh-Ting; Wei, Yau-Huei; Chen, Fang-Pey; Wang, Shengwen; Wu, Po-Chang; Yen, Hung-Rong; Chen, Tzeng-Ji; Chang, Hen-Hong

2015-01-01

This large-scale survey aimed to evaluate frequencies and patterns of Chinese herbal medicine (CHM) used for Sjögren's syndrome (SS) in Taiwan by analyzing the National Health Insurance Research Database (NHIRD) for cases in which CHM was used as an alternative therapy to Western medicine for improving patients' discomforts. We analyzed cases of SS principal diagnosis (ICD-9:710.2) with a catastrophic illness certificate (CIC) in traditional Chinese medicine (TCM) outpatient clinics from three cohorts of the Longitudinal Health Insurance Database (LHID) in the NHIRD between 2002 and 2011. CHM prescription patterns for SS were evaluated from claimed visitation files and corresponding prescription files. There were 15,914 SS patients with CIC (SS/CIC), and we found only 130 SS/CIC cases visiting TCM clinics in LHID2000, 133 in LHID2005, and 126 in LHID2010. After removing duplicate data, 366 SS/CIC and 4,867 visits were analyzed. The 50–59 year age group showed the highest ratio (29.51%) in both women and men. “Qi-Ju-Di-Huang-Wan” and “Xuan-Shen” (Scrophularia ningpoensis Hemsl.) was the most commonly used formula and single herb, respectively. “Qi-Ju-Di-Huang-Wan, Gan-Lu-Yin, Xuan-Shen, Mai-Men-Dong (Ophiopogon japonicus (L. f.) Ker-Gawl.), and Sheng-Di-Huang (raw Rehmannia glutinosa Libosch)” were the core pattern prescriptions in treating SS/CIC. PMID:25923413

Prioritizing individual genetic variants after kernel machine testing using variable selection.

PubMed

He, Qianchuan; Cai, Tianxi; Liu, Yang; Zhao, Ni; Harmon, Quaker E; Almli, Lynn M; Binder, Elisabeth B; Engel, Stephanie M; Ressler, Kerry J; Conneely, Karen N; Lin, Xihong; Wu, Michael C

2016-12-01

Kernel machine learning methods, such as the SNP-set kernel association test (SKAT), have been widely used to test associations between traits and genetic polymorphisms. In contrast to traditional single-SNP analysis methods, these methods are designed to examine the joint effect of a set of related SNPs (such as a group of SNPs within a gene or a pathway) and are able to identify sets of SNPs that are associated with the trait of interest. However, as with many multi-SNP testing approaches, kernel machine testing can draw conclusion only at the SNP-set level, and does not directly inform on which one(s) of the identified SNP set is actually driving the associations. A recently proposed procedure, KerNel Iterative Feature Extraction (KNIFE), provides a general framework for incorporating variable selection into kernel machine methods. In this article, we focus on quantitative traits and relatively common SNPs, and adapt the KNIFE procedure to genetic association studies and propose an approach to identify driver SNPs after the application of SKAT to gene set analysis. Our approach accommodates several kernels that are widely used in SNP analysis, such as the linear kernel and the Identity by State (IBS) kernel. The proposed approach provides practically useful utilities to prioritize SNPs, and fills the gap between SNP set analysis and biological functional studies. Both simulation studies and real data application are used to demonstrate the proposed approach. © 2016 WILEY PERIODICALS, INC.

From photoelectron detachment spectra of BrHBr{sup −}, BrDBr{sup −} and IHI{sup −}, IDI{sup −} to vibrational bonding of BrMuBr and IMuI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Manz, Jörn; Freie Universität Berlin, Institut für Chemie und Biochemie, 14195 Berlin; Sato, Kazuma

2015-04-28

Photoelectron detachment XLX{sup −}(00{sup 0}0) + hν → XLX(vib) + e{sup −} + KER (X = Br or I, L = H or D) at sufficiently low temperatures photoionizes linear dihalogen anions XLX{sup −} in the vibrational ground state (v{sub 1}v{sub 2}{sup l}v{sub 3} = 00{sup 0}0) and prepares the neutral radicals XLX(vib) in vibrational states (vib). At the same time, part of the photon energy (hν) is converted into kinetic energy release (KER) of the electron [R. B. Metz, S. E. Bradforth, and D. M. Neumark, Adv. Chem. Phys. 81, 1 (1992)]. The process may be described approximately inmore » terms of a Franck-Condon type transfer of the vibrational wavefunction representing XLX{sup −}(00{sup 0}0) from the domain close to the minimum of its potential energy surface (PES) to the domain close to the linear transition state of the PES of the neutral XLX. As a consequence, prominent peaks of the photoelectron detachment spectra (pds) correlate with the vibrational energies E{sub XLX,vib} of states XLX(vib) which are centered at linear transition state. The corresponding vibrational quantum numbers may be labeled vib = (v{sub 1}v{sub 2}{sup l}v{sub 3}) = (00{sup 0}v{sub 3}). Accordingly, the related most prominent peaks in the pds are labeled v{sub 3}. We construct a model PES which mimics the “true” PES in the domain of transition state such that it supports vibrational states with energies E{sub XLX,pds,00{sup 0}v{sub 3}} close to the peaks of the pds labeled v{sub 3} = 0, 2, and 4. Subsequently, the same model PES is also used to calculate approximate values of the energies E{sub XMuX,00{sup 0}0} of the isotopomers XMuX(00{sup 0}0). For the heavy isotopomers XHX and XDX, it turns out that all energies E{sub XLX,00{sup 0}v{sub 3}} are above the threshold for dissociation, which means that all heavy XLX(00{sup 0}v{sub 3}) with wavefunctions centered at the transition state are unstable resonances with finite lifetimes. Turning the table, bound states of the heavy XLX

The Impact of a Ligand Binding on Strand Migration in the SAM-I Riboswitch

PubMed Central

Huang, Wei; Kim, Joohyun; Jha, Shantenu; Aboul-ela, Fareed

2013-01-01

Riboswitches sense cellular concentrations of small molecules and use this information to adjust synthesis rates of related metabolites. Riboswitches include an aptamer domain to detect the ligand and an expression platform to control gene expression. Previous structural studies of riboswitches largely focused on aptamers, truncating the expression domain to suppress conformational switching. To link ligand/aptamer binding to conformational switching, we constructed models of an S-adenosyl methionine (SAM)-I riboswitch RNA segment incorporating elements of the expression platform, allowing formation of an antiterminator (AT) helix. Using Anton, a computer specially developed for long timescale Molecular Dynamics (MD), we simulated an extended (three microseconds) MD trajectory with SAM bound to a modeled riboswitch RNA segment. Remarkably, we observed a strand migration, converting three base pairs from an antiterminator (AT) helix, characteristic of the transcription ON state, to a P1 helix, characteristic of the OFF state. This conformational switching towards the OFF state is observed only in the presence of SAM. Among seven extended trajectories with three starting structures, the presence of SAM enhances the trend towards the OFF state for two out of three starting structures tested. Our simulation provides a visual demonstration of how a small molecule (<500 MW) binding to a limited surface can trigger a large scale conformational rearrangement in a 40 kDa RNA by perturbing the Free Energy Landscape. Such a mechanism can explain minimal requirements for SAM binding and transcription termination for SAM-I riboswitches previously reported experimentally. PMID:23704854

Investigating everyday measures through exploratory talk: whole class plenary intervention and landscape study at grade four

NASA Astrophysics Data System (ADS)

Gade, Sharada; Blomqvist, Charlotta

2018-03-01

We report an exploratory talk based, whole class plenary intervention, in relation to students' understanding of everyday measures and measurement, in a grade four classroom at a grade 4-6 school in Sweden. Extended, project related, teacher-researcher collaboration forms basis for such cultural historical activity theory or CHAT based efforts. As formative intervention, the conduct of the plenary is not pre-determined but embedded in ongoing curricular realities, with the agency of students and teacher promoted, pedagogical ideas reutilised and the role of researcher viewed as supporting design and growth of the intervention. Under Charlotta's guidance as teacher, the plenary is opportunity for her students to examine improbable scenarios such as, Can Eva and Anton measure the length of Sweden on foot, Can Lars and Iris measure their age in decimeters. A zone of proximal development is created, in which students make the transition from spontaneous to scientific concepts and learn how various units of measurement are objects-that-can-be-used-for-certain-purposes. With opportunity for critical and reflective inquiry, in a plenary designed to lead development, Charlotta's students look beyond the making of rote measurements and articulate a theory of measure in nascent terms. Such a landscape of teaching-learning is finally understood in terms of the nature of talk that was facilitated, the manner of pedagogy utilised, the style of teaching exercised and the kind of learning that was demanded of her students.

Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex.

PubMed

Raveh, Barak; Karp, Jerome M; Sparks, Samuel; Dutta, Kaushik; Rout, Michael P; Sali, Andrej; Cowburn, David

2016-05-03

Nucleocytoplasmic transport is mediated by the interaction of transport factors (TFs) with disordered phenylalanine-glycine (FG) repeats that fill the central channel of the nuclear pore complex (NPC). However, the mechanism by which TFs rapidly diffuse through multiple FG repeats without compromising NPC selectivity is not yet fully understood. In this study, we build on our recent NMR investigations showing that FG repeats are highly dynamic, flexible, and rapidly exchanging among TF interaction sites. We use unbiased long timescale all-atom simulations on the Anton supercomputer, combined with extensive enhanced sampling simulations and NMR experiments, to characterize the thermodynamic and kinetic properties of FG repeats and their interaction with a model transport factor. Both the simulations and experimental data indicate that FG repeats are highly dynamic random coils, lack intrachain interactions, and exhibit significant entropically driven resistance to spatial confinement. We show that the FG motifs reversibly slide in and out of multiple TF interaction sites, transitioning rapidly between a strongly interacting state and a weakly interacting state, rather than undergoing a much slower transition between strongly interacting and completely noninteracting (unbound) states. In the weakly interacting state, FG motifs can be more easily displaced by other competing FG motifs, providing a simple mechanism for rapid exchange of TF/FG motif contacts during transport. This slide-and-exchange mechanism highlights the direct role of the disorder within FG repeats in nucleocytoplasmic transport, and resolves the apparent conflict between the selectivity and speed of transport.

["To suffer an ordeal": Some Swedish physicians' struggle during the nineteenth century against unhygienic female dress].

PubMed

Nordström, M

1993-01-01

Tight-lacing of the female body has been practised at various periods in the history of costume. During the romantic age of the nineteenth century the ideal women had to be pale, weak and often pathologically thin. She was supposed to be of a humble disposition and subservient to her husband (according to the doctrine of subordination). Women laced themselves so tightly that their bodies became deformed, with physical injuries and damage to the internal organs as a consequence. Competition for suitable husbands was keen, since marriage was the only honourable way for a woman to ensure that she would be provided for. It was also in the nineteenth century that doctors were beginning to fight against endemic disease and to argue for a more hygienic way of life. They maintained that women were slaves to fashion and that they dressed in an unhygienic way. Above all, they campaigned against the use of tight-laced corsets. Swedish doctors, such as Anton Nyström, Truls Johan Harterlius and Karolina Widerström headed the fight against the use of laced corsetes, on both medical and social grounds. An improved and "informed" costume was introduced which was meant to allow women greater freedom of movement, thus enabling them to live a more natural life. It was, however, not until 1910 that the tightly-laced corset was abandoned. The conclusion of this is that the history of costume is "the history of absurd follies".

Attention changes perceived size of moving visual patterns.

PubMed

Anton-Erxleben, Katharina; Henrich, Christian; Treue, Stefan

2007-08-23

Spatial attention shifts receptive fields in monkey extrastriate visual cortex toward the focus of attention (S. Ben Hamed, J. R. Duhamel, F. Bremmer, & W. Graf, 2002; C. E. Connor, J. L. Gallant, D. C. Preddie, & D. C. Van Essen, 1996; C. E. Connor, D. C. Preddie, J. L. Gallant, & D. C. Van Essen, 1997; T. Womelsdorf, K. Anton-Erxleben, F. Pieper, & S. Treue, 2006). This distortion in the retinotopic distribution of receptive fields might cause distortions in spatial perception such as an increase of the perceived size of attended stimuli. Here we test for such an effect in human subjects by measuring the point of subjective equality (PSE) for the perceived size of a neutral and an attended stimulus when drawing automatic attention to one of two spatial locations. We found a significant increase in perceived size of attended stimuli. Depending on the absolute stimulus size, this effect ranged from 4% to 12% and was more pronounced for smaller than for larger stimuli. In our experimental design, an attentional effect on task difficulty or a cue bias might influence the PSE measure. We performed control experiments and indeed found such effects, but they could only account for part of the observed results. Our findings demonstrate that the allocation of transient spatial attention onto a visual stimulus increases its perceived size and additionally biases subjects to select this stimulus for a perceptual judgment.

Rheological Characterization and Cluster Classification of Iranian Commercial Foods, Drinks and Desserts to Recommend for Esophageal Dysphagia Diets

PubMed Central

ZARGARAAN, Azizollaah; OMARAEE, Yasaman; RASTMANESH, Reza; TAHERI, Negin; FADAVI, Ghasem; FADAEI, Morteza; MOHAMMADIFAR, Mohammad Amin

2013-01-01

Abstract Background In the absence of dysphagia-oriented food products, rheological characterization of available food items is of importance for safe swallowing and adequate nutrient intake of dysphagic patients. In this way, introducing alternative items (with similar ease of swallow) is helpful to improve quality of life and nutritional intake of esophageal cancer dysphagia patients. The present study aimed at rheological characterization and cluster classification of potentially suitable foodstuffs marketed in Iran for their possible use in dysphagia diets. Methods In this descriptive study, rheological data were obtained during January and February 2012 in Rheology Lab of National Nutrition and Food Technology Research Institute Tehran, Iran. Steady state and oscillatory shear parameters of 39 commercial samples were obtained using a Physica MCR 301 rheometer (Anton-Paar, GmbH, Graz, Austria). Matlab Fuzzy Logic Toolbox (R2012 a) was utilized for cluster classification of the samples. Results Using an extended list of rheological parameters and fuzzy logic methods, 39 commercial samples (drinks, main courses and desserts) were divided to 5 clusters and degree of membership to each cluster was stated by a number between 0 and 0.99. Conclusion Considering apparent viscosity of foodstuffs as a single criterion for classification of dysphagia-oriented food products is shortcoming of current guidelines in dysphagia diets. Authors proposed to some revisions in classification of dysphagia-oriented food products and including more rheological parameters (especially, viscoelastic parameters) in the classification. PMID:26060647

Observations of CI Cam needed to support spectroscopy

NASA Astrophysics Data System (ADS)

Waagen, Elizabeth O.

2016-10-01

Kelly Gourdji and Marcella Wijngaarden (graduate students at the University of Amsterdam/Anton Pannekoek Institute for Astronomy) have requested AAVSO observers' assistance in providing optical photometry of CI Cam in support of their high-resolution spectroscopy from now through January 2017. They write: "...We are currently observing the variable star CI Cam (the B[e] optical counterpart of a HMXB system) with the HERMES spectrograph at the Mercator Telescope in La Palma. Having observed the star for three nights now, the object appears to be in outburst. In particular, H alpha was measured to be 80 times the continuum flux, and increasing between Oct. 9 and 12. This is similar to the previous outburst in 2004/5. Photometric data obtained during the 2004/5 outburst suggested an outburst duration of about 3 months and a peak brightness of 11.2 in the V band." More information is available in ATel #9634 (Wijngaarden et al.). Multiple snapshot observations per night in BVRI are requested beginning immediately and continuing through January 2017. Time series are not necessary unless requested later via an AAVSO Special Notice. Observations made using other filters will be useful as well as long as there are multiple observations in these bands. Finder charts with sequence may be created using the AAVSO Variable Star Plotter (https://www.aavso.org/vsp). Observations should be submitted to the AAVSO International Database. See full Alert Notice for more details.

Search for breast cancer biomarkers in fractionated serum samples by protein profiling with SELDI-TOF MS.

PubMed

Opstal-van Winden, Annemieke W J; Beijnen, Jos H; Loof, Arnoud; van Heerde, Waander L; Vermeulen, Roel; Peeters, Petra H M; van Gils, Carla H

2012-01-01

Many high-abundant acute phase reactants have been previously detected as potential breast cancer biomar-kers. However, they are unlikely to be specific for breast cancer. Cancer-specific biomarkers are thought to be among the lower abundant proteins. We aimed to detect lower abundant discriminating proteins by performing serum fractionation by strong anion exchange chromatography preceding protein profiling with SELDI-TOF MS. In a pilot study, we tested the different fractions resulting from fractionation, on several array types. Fraction 3 on IMAC30 and Fraction 6 on Q10 yielded the most discriminative proteins and were used for serum protein profiling of 73 incident breast cancer cases and 73 matched controls. Eight peaks showed statistically significantly different intensities between cases and controls (P⧁0.05), and had less than 10% chance to be a false-positive finding. Seven of these were tentatively identified as apolipoprotein C-II (m/z 8,909), oxidized apolipoprotein C-II (m/z 8,925), apolipoprotein C-III (m/z 8,746), fragment of coagulation factor XIIIa (m/z 3,959), heterodimer of apolipoprotein A-I and apolipoprotein A-II (m/z 45,435), hemoglobin B-chain (m/z 15,915), and post-translational modified hemoglobin (m/z 15,346). By extensive serum fractionation, we detected many more proteins than in previous studies without fractionation. However, discriminating proteins were still high abundant. Results indicate that either lower abundant proteins are less distinctive, or more rigorous fractionation and selective protein depletion, or a more sensitive assay, are needed to detect lower abundant discriminative proteins. © 2012 Wiley Periodicals, Inc.

The northern population development; colonization and mortality in Swedish Sápmi, 1776-1895.

PubMed

Sköld, Peter; Axelsson, Per

2008-02-01

The aim of the Consequence of Colonization project is to study population development and mortality in Swedish Sápmi. This article, the first to be drawn from our research, compares these changes between Sami and non-Sami, South and North Sami. Study design. Longitudinal individual based data from computerized records ofthe Glillivare, Undersåker and Frostviken parishes, divided into 2 40-year periods: 1776-1815 and 1856-1895. The main source material used for the present study was a set of data files from the Demographic Data Base (DDB) at Umeå University, the largest historical database in Europe. A Sami cohort was created by indicators of ethnicity in the parish registers, and was later extended with automatic linkages to children and parents. Sami mortality rates show great fluctuations during the period 1776-1815, almost always peaking at a higher rate than in the rest of Sweden. The non-Sami group had lower mortality rates compared with both Sweden as a whole and the Sami in the parish. Between 1856 and 1895, the non-Sami experienced a very small reduction in their mortality rates and the Sami experienced overall improvement in their health status. Significant differences in age-specific mortality appear when the South and North Sami are compared, showing that the South Sami had far lower child mortality rates. The Sami population's health status improved during the nineteenth century. This indicates that they had advanced in the epidemiologic transition model. A corresponding change is not found for the non-Sami group.

European Glaucoma Society Terminology and Guidelines for Glaucoma, 4th Edition - Part 1Supported by the EGS Foundation

PubMed Central

2017-01-01

Nordmann Norbert Pfeiffer Luis Abegao Pinto Luca Rossetti John Salmon Leo Schmetterer Riccardo Scotto Tarek Shaarawy Ingeborg Stalmans Gordana Sunaric Megevand Ernst Tamm John Thygesen Fotis Topouzis Carlo Enrico Traverso Anja Tuulonen Ananth Viswanathan Thierry Zeyen The Guidelines Task Force  Luca Bagnasco Anders Heijl Carlo Enrico Traverso Augusto Azuara Blanco Alessandro Bagnis David Garway Heath Michele Iester Yves Lachkar Ingeborg Stalmans Gordana Sunaric Mégevand Fotis Topouzis Anja Tuulonen Ananth Viswanathan The EGS Executive Committee  Carlo Enrico Traverso (President) Anja Tuulonen (Vice President) Roger Hitchings (Past President) Anton Hommer (Treasurer) Barbara Cvenkel Julian Garcia Feijoo David Garway Heath Norbert Pfeiffer Ingeborg Stalmans The Board of the European Glaucoma Society Foundation  Roger Hitchings (Chair) Carlo E. Traverso (Vice Chair) Franz Grehn Anders Heijl John Thygesen Fotis Topouzis Thierry Zeyen The EGS Committees  CME and Certification  Gordana Sunaric Mégevand (Chair) Carlo Enrico Traverso (Co-chair) Delivery of Care  Anton Hommer (Chair) EU Action  Thierry Zeyen (Chair) Carlo E. Traverso (Co-chair) Education  John Thygesen (Chair) Fotis Topouzis (Co-chair) Glaucogene  Ananth Viswanathan (Chair) Fotis Topouzis (Co-chair) Industry Liaison  Roger Hitchings (Chair) Information Technology  Ingeborg Stalmans (Chair) Carlo E. Traverso (Co-chair) National Society Liaison  Anders Heijl (Chair) Program Planning  Fotis Topouzis (Chair) Ingeborg Stalmans (Co-chair) Quality and Outcomes  Anja Tuulonen (Chair) Augusto Azuara Blanco (Co-chair) Scientific  Franz Grehn (Chair) David Garway Heath (Co-chair) PMID:27378485

Analysis of the IMS Location Accuracy in Northern Eurasia and North America Using Regional and Global Pn Travel-time Tables

NASA Astrophysics Data System (ADS)

United States Calibration Working Group, Russian Federation/

- Joint Research Program of Seismic Calibration of the International Monitoring System (IMS) in Northern Eurasia and North America has been signed by the Nuclear Treaty Programs Office (NTPO), Department of Defense USA, and the Special Monitoring Service (SMS) of the Ministry of Defense, Russian Federation (RF). Under the Program historical data from nuclear and large chemical explosions of known location and shot time, together with appropriate geological and geophysical data, has been used to derive regional Pn/P travel-time tables for seismic event location within the lower 48 States of the USA and the European part of the RF. These travel-time tables are up to 5seconds faster in shields than the IASPEI91 tables, and up to 5seconds slower in the Western USA. Relocation experiments using the regional Pn travel-time curves and surrogate networks for the IMS network generally improved locations for regional seismic events. The distance between true and estimated location (mislocation) was decreased from an average of 18.8km for the IASPEI91 tables to 10.1km for the regional Pn travel-time tables. However, the regional travel-time table approach has limitations caused by travel-time variations inside major tectonic provinces and paths crossing several tectonic provinces with substantially different crustal and upper mantle velocity structure.The RF members of the Calibration Working Group (WG): Colonel Vyacheslav Gordon (chairman); Dr. Prof. Marat Mamsurov, and Dr. Nikolai Vasiliev. The US members of the WG: Dr. Anton Dainty (chairman), Dr. Douglas Baumgardt, Mr. John Murphy, Dr. Robert North, and Dr. Vladislav Ryaboy.

On the history of gout: paleopathological evidence from the Medici family of Florence.

PubMed

Giuffra, Valentina; Minozzi, Simona; Vitiello, Angelica; Fornaciari, Antonio

2017-01-01

Throughout history, gout has been referred to as the "disease of the kings", and has been clearly associated with the lifestyle of the aristocratic social classes. According to the written sources, several members of the famous Medici family of Florence suffered from an arthritic disease that contemporary physicians called "gout". A paleopathological study carried out on the skeletal remains of some members of the family, exhumed from their tombs in the Church of San Lorenzo in Florence, offered a unique opportunity to directly investigate the evidence of the arthritic diseases affecting this elite group. The skeletal remains of several members of the family were examined macroscopically and submitted to x-ray investigation. The results of the study allowed us to ascertain that the so-called "gout of the Medici" should be considered the clinical manifestation of three different joint conditions: diffuse idiopathic skeletal hyperostosis, rheumatoid arthritis and uratic gout. In particular, uric acid gout was diagnosed in the Grand Duke Ferdinand I (1549-1609). Recently, a new case of this disease was diagnosed in Anton Francesco Maria (1618-1659), a probable illegitimate member of the family. With this new case, uratic gout was observed in 2 out of 9 adult males, leading to suppose that the disease should have been a common health problem within the family. The aetiology of the disease has to be searched in environmental factors, since both historical and paleonutritional studies demonstrated that the diet of this aristocratic court was rich in meat and wine.

Evaluation of tribological properties of selected engine oils during operation of the friction pairs of steel-on-steel

NASA Astrophysics Data System (ADS)

Barszcz, Marcin; Józwik, Jerzy; Dziedzic, Krzysztof; Stec, Kamil

2017-10-01

The paper includes an assessment of the tribological properties of mineral and synthetic Lotos oil marked SAE 15W/40 and SAE 5W/40 at ambient temperature and 100 °C. The evaluation was based on the analysis of the tribological properties of friction couple consumables. Tribological tests were performed using the Anton Paar THT 1000 high temperature tribotester according to ASTM G133. Tribological properties were investigated using the "ball on disc" method. The change of friction coefficient, friction couple temperature, volume wear of samples and counter-samples and Hertz stresses were evaluated. In addition, hardness tests of the friction couple materials as well as surface roughness before and after friction were performed. On the basis of tribological studies, it was noted that Lotos Synthetic 5W/40 oil has better cooling properties compared. For both oils the coefficient of friction was lower at ambient temperature than at 100 °C. The highest value of volume wear of the sample was noted for the combination lubricated with Mineral Oil 15W/40 at 100 °C (0.0143 mm3) while for counter-sample lubricated with synthetic oil at ambient temperature (0.0039 mm3). The highest sample wear coefficient was recorded for the mineral oil lubricated at temperature of 100 °C (3.585*10-7 mm3/N/m) while for counter-sample lubricated with synthetic oil at ambient temperature (9.8768*10-8 mm3/N/m). The Hertz stress for each test couple had a value of 1.787 GPa.

Involvement of the exomer complex in the polarized transport of Ena1 required for Saccharomyces cerevisiae survival against toxic cations.

PubMed

Anton, Carlos; Zanolari, Bettina; Arcones, Irene; Wang, Congwei; Mulet, Jose Miguel; Spang, Anne; Roncero, Cesar

2017-12-01

Exomer is an adaptor complex required for the direct transport of a selected number of cargoes from the trans -Golgi network (TGN) to the plasma membrane in Saccharomyces cerevisiae However, exomer mutants are highly sensitive to increased concentrations of alkali metal cations, a situation that remains unexplained by the lack of transport of any known cargoes. Here we identify several HAL genes that act as multicopy suppressors of this sensitivity and are connected to the reduced function of the sodium ATPase Ena1. Furthermore, we find that Ena1 is dependent on exomer function. Even though Ena1 can reach the plasma membrane independently of exomer, polarized delivery of Ena1 to the bud requires functional exomer. Moreover, exomer is required for full induction of Ena1 expression after cationic stress by facilitating the plasma membrane recruitment of the molecular machinery involved in Rim101 processing and activation of the RIM101 pathway in response to stress. Both the defective localization and the reduced levels of Ena1 contribute to the sensitivity of exomer mutants to alkali metal cations. Our work thus expands the spectrum of exomer-dependent proteins and provides a link to a more general role of exomer in TGN organization. © 2017 Anton et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

"No doubt this childhood disease on Vestmannö can be prevented"--neonatal tetanus on the Westman Islands.

PubMed

Jacobsen, Geir W; Hem, Erlend; Sigurdsson, Jóhann A

2011-04-08

At the beginning of the 1800 s neonatal tetanus was a major health hazard on the Westman Islands, an archipelago immediately south of Iceland. Up to 60–70% of newborn babies died in the course of the first two weeks of life, and Danish health authorities were almost helpless in the face of this mysterious disease. In 1847 the young Danish doctor Peter Anton Schleisner (1818-1900) was sent to the islands to investigate the conditions there. He established a maternity hospital, gave advice on hygiene and encouraged breast-feeding and a number of changes in diet. Since there was no known treatment, Schleisner's only option was to resort to preventive measures. He dressed the umbilical stump with balsamum copaivae and tried well-established methods such as opium tincture with saffron and mercurial ointment if there was any sign of infection. By the time he returned to Denmark after nine months, mortality had been halved. Neonatal mortality on the Westman Islands remained at the same low level throughout the rest of the 19th century. According to popular belief this was due to the naflaolian (navel oil) which Schleisner introduced. Nevertheless, it can be partly attributed to generally improved living standards, a relatively higher number of mothers in better social circumstances, a greater urban influence, changed lifestyle and hygienic measures. Schleisner's efforts are considered to have had major significance when conditions are compared with those on the Scottish island of St Kilda where the situation was the same and improved only just before the turn of the century.

Energy landscape of LeuT from molecular simulations

NASA Astrophysics Data System (ADS)

Gur, Mert; Zomot, Elia; Cheng, Mary Hongying; Bahar, Ivet

2015-12-01

The bacterial sodium-coupled leucine transporter (LeuT) has been broadly used as a structural model for understanding the structure-dynamics-function of mammalian neurotransmitter transporters as well as other solute carriers that share the same fold (LeuT fold), as the first member of the family crystallographically resolved in multiple states: outward-facing open, outward-facing occluded, and inward-facing open. Yet, a complete picture of the energy landscape of (sub)states visited along the LeuT transport cycle has been elusive. In an attempt to visualize the conformational spectrum of LeuT, we performed extensive simulations of LeuT dimer dynamics in the presence of substrate (Ala or Leu) and co-transported Na+ ions, in explicit membrane and water. We used both conventional molecular dynamics (MD) simulations (with Anton supercomputing machine) and a recently introduced method, collective MD, that takes advantage of collective modes of motions predicted by the anisotropic network model. Free energy landscapes constructed based on ˜40 μs trajectories reveal multiple substates occluded to the extracellular (EC) and/or intracellular (IC) media, varying in the levels of exposure of LeuT to EC or IC vestibules. The IC-facing transmembrane (TM) helical segment TM1a shows an opening, albeit to a smaller extent and in a slightly different direction than that observed in the inward-facing open crystal structure. The study provides insights into the spectrum of conformational substates and paths accessible to LeuT and highlights the differences between Ala- and Leu-bound substates.

Rheological Characterization of Vegetal Pear (Sechium edule)

NASA Astrophysics Data System (ADS)

Castillo-Reyes, José A.; Luna-Solano, Guadalupe; Cantú-Lozano, Denis

2008-07-01

The national production of Mexican vegetal pear (Sechium edule) is located at the present time in more than 130,000 ton/year. The vegetal pear that produced in the center zone of the state of Veracruz is known in international markets; however it is a product that practically has not been studied. This work identifies the rheological behavior of vegetal pear (Sechium edule). A rheometer MCR301 of Anton Paar was utilized for viscosity and shear stress measurements. The objective of this experimental was modeling the rheological behavior of vegetal pear suspensions at three concentrations (1, 2 and 3% w/w), three particle size (1.00, 1.19 and 1.40 mm), at the same conditions of temperature (25, 40 and 70 °C). The results showed that all the suspensions there was a phenomenological behavior as a dilatants fluid (n>1) the performance of flow was represented by the Herschel-Bulkley model, and present values of "yield stress" between from 0.1 to 15 Pa for the different experiments. During evaluation of the activation energy of the suspensions of vegetal pear was found that decreases from 154.4039 kJ/mol to 9.1086 kJ/mol for a particle size of 1.00 mm to 1.4 mm, which implies that the effect of temperature is higher with smaller grains, in this case 1.00 mm. Furthermore, we assessed the effect of particle size by the Péclet number, showing an increase of the viscosity when the Péclet number also increases.

Energy landscape of LeuT from molecular simulations.

PubMed

Gur, Mert; Zomot, Elia; Cheng, Mary Hongying; Bahar, Ivet

2015-12-28

The bacterial sodium-coupled leucine transporter (LeuT) has been broadly used as a structural model for understanding the structure-dynamics-function of mammalian neurotransmitter transporters as well as other solute carriers that share the same fold (LeuT fold), as the first member of the family crystallographically resolved in multiple states: outward-facing open, outward-facing occluded, and inward-facing open. Yet, a complete picture of the energy landscape of (sub)states visited along the LeuT transport cycle has been elusive. In an attempt to visualize the conformational spectrum of LeuT, we performed extensive simulations of LeuT dimer dynamics in the presence of substrate (Ala or Leu) and co-transported Na(+) ions, in explicit membrane and water. We used both conventional molecular dynamics (MD) simulations (with Anton supercomputing machine) and a recently introduced method, collective MD, that takes advantage of collective modes of motions predicted by the anisotropic network model. Free energy landscapes constructed based on ∼40 μs trajectories reveal multiple substates occluded to the extracellular (EC) and/or intracellular (IC) media, varying in the levels of exposure of LeuT to EC or IC vestibules. The IC-facing transmembrane (TM) helical segment TM1a shows an opening, albeit to a smaller extent and in a slightly different direction than that observed in the inward-facing open crystal structure. The study provides insights into the spectrum of conformational substates and paths accessible to LeuT and highlights the differences between Ala- and Leu-bound substates.

Cosmic acceleration from a single fluid description

NASA Astrophysics Data System (ADS)

Capozziello, Salvatore; D'Agostino, Rocco; Luongo, Orlando

2018-06-01

We here propose a new class of barotropic factor for matter, motivated by properties of isotropic deformations of crystalline solids. Our approach is dubbed Anton-Schmidt's equation of state and provides a non-vanishing, albeit small, pressure term for matter. The corresponding pressure is thus proportional to the logarithm of universe's volume, i.e. to the density itself since V ∝ρ-1. In the context of solid state physics, we demonstrate that by only invoking standard matter with such a property, we are able to frame the universe speed up in a suitable way, without invoking a dark energy term by hand. Our model extends a recent class of dark energy paradigms named logotropic dark fluids and depends upon two free parameters, namely n and B. Within the Debye approximation, we find that n and B are related to the Grüneisen parameter and the bulk modulus of crystals. We thus show the main differences between our model and the logotropic scenario, and we highlight the most relevant properties of our new equation of state on the background cosmology. Discussions on both kinematics and dynamics of our new model have been presented. We demonstrate that the ΛCDM model is inside our approach, as limiting case. Comparisons with CPL parametrization have been also reported in the text. Finally, a Monte Carlo analysis on the most recent low-redshift cosmological data allowed us to place constraints on n and B. In particular, we found n = - 0 . 147-0.107+0.113 and B = 3.54 × 10-3.

How far are rheological parameters from amplitude sweep tests predictable using common physicochemical soil properties?

NASA Astrophysics Data System (ADS)

Stoppe, N.; Horn, R.

2017-01-01

A basic understanding of soil behavior on the mesoscale resp. macroscale (i.e. soil aggregates resp. bulk soil) requires knowledge of the processes at the microscale (i.e. particle scale), therefore rheological investigations of natural soils receive growing attention. In the present research homogenized and sieved (< 2 mm) samples from Marshland soils of the riparian zone of the River Elbe (North Germany) were analyzed with a modular compact rheometer MCR 300 (Anton Paar, Ostfildern, Germany) with a profiled parallel-plate measuring system. Amplitude sweep tests (AST) with controlled shear deformation were conducted to investigate the viscoelastic properties of the studied soils under oszillatory stress. The gradual depletion of microstructural stiffness during AST cannot only be characterized by the well-known rheological parameters G, G″ and tan δ but also by the dimensionless area parameter integral z, which quantifies the elasticity of microstructure. To discover the physicochemical parameters, which influences the microstructural stiffness, statistical tests were used taking the combined effects of these parameters into account. Although the influence of the individual factors varies depending on soil texture, the physicochemical features significantly affecting soil micro structure were identified. Based on the determined statistical relationships between rheological and physicochemical parameters, pedotransfer functions (PTF) have been developed, which allow a mathematical estimation of the rheological target value integral z. Thus, stabilizing factors are: soil organic matter, concentration of Ca2+, content of CaCO3 and pedogenic iron oxides; whereas the concentration of Na+ and water content represent structurally unfavorable factors.

Energy landscape of LeuT from molecular simulations

PubMed Central

Gur, Mert; Zomot, Elia; Cheng, Mary Hongying; Bahar, Ivet

2015-01-01

The bacterial sodium-coupled leucine transporter (LeuT) has been broadly used as a structural model for understanding the structure-dynamics-function of mammalian neurotransmitter transporters as well as other solute carriers that share the same fold (LeuT fold), as the first member of the family crystallographically resolved in multiple states: outward-facing open, outward-facing occluded, and inward-facing open. Yet, a complete picture of the energy landscape of (sub)states visited along the LeuT transport cycle has been elusive. In an attempt to visualize the conformational spectrum of LeuT, we performed extensive simulations of LeuT dimer dynamics in the presence of substrate (Ala or Leu) and co-transported Na+ ions, in explicit membrane and water. We used both conventional molecular dynamics (MD) simulations (with Anton supercomputing machine) and a recently introduced method, collective MD, that takes advantage of collective modes of motions predicted by the anisotropic network model. Free energy landscapes constructed based on ∼40 μs trajectories reveal multiple substates occluded to the extracellular (EC) and/or intracellular (IC) media, varying in the levels of exposure of LeuT to EC or IC vestibules. The IC-facing transmembrane (TM) helical segment TM1a shows an opening, albeit to a smaller extent and in a slightly different direction than that observed in the inward-facing open crystal structure. The study provides insights into the spectrum of conformational substates and paths accessible to LeuT and highlights the differences between Ala- and Leu-bound substates. PMID:26723619

Differential Inflammatory-Response Kinetics of Human Keratinocytes upon Cytosolic RNA- and DNA-Fragment Induction.

PubMed

Danis, Judit; Janovák, Luca; Gubán, Barbara; Göblös, Anikó; Szabó, Kornélia; Kemény, Lajos; Bata-Csörgő, Zsuzsanna; Széll, Márta

2018-03-08

Keratinocytes are non-professional immune cells contributing actively to innate immune responses partially by reacting to a wide range of molecular patterns by activating pattern recognition receptors. Cytosolic nucleotide fragments as pathogen- or self-derived trigger factors are activating inflammasomes and inducing anti-viral signal transduction pathways as well as inducing expression of inflammatory cytokines. We aimed to compare the induced inflammatory reactions in three keratinocyte cell types-normal human epidermal keratinocytes, the HaCaT cell line and the HPV-KER cell line-upon exposure to the synthetic RNA and DNA analogues poly(I:C) and poly(dA:dT) to reveal the underlying signaling events. Both agents induced the expression of interleukin-6 and tumor necrosis factor α in all cell types; however, notable kinetic and expression level differences were found. Western blot analysis revealed rapid activation of the nuclear factor κB (NF-κB), mitogen activated protein kinase and signal transducers of activator of transcription (STAT) signal transduction pathways in keratinocytes upon poly(I:C) treatment, while poly(dA:dT) induced slower activation. Inhibition of NF-κB, p38, STAT-1 and STAT-3 signaling resulted in decreased cytokine expression, whereas inhibition of mitogen-activated protein kinase kinase 1/2 (MEK1/2) signaling showed a negative feedback role in both poly(I:C)- and poly(dA:dT)-induced cytokine expression. Based on our in vitro results nucleotide fragments are able to induce inflammatory reactions in keratinocytes, but with different rate and kinetics of cytokine expression, explained by faster activation of signaling routes by poly(I:C) than poly(dA:dT).

Differential Inflammatory-Response Kinetics of Human Keratinocytes upon Cytosolic RNA- and DNA-Fragment Induction

PubMed Central

Danis, Judit; Janovák, Luca; Gubán, Barbara; Göblös, Anikó; Szabó, Kornélia; Bata-Csörgő, Zsuzsanna; Széll, Márta

2018-01-01

Keratinocytes are non-professional immune cells contributing actively to innate immune responses partially by reacting to a wide range of molecular patterns by activating pattern recognition receptors. Cytosolic nucleotide fragments as pathogen- or self-derived trigger factors are activating inflammasomes and inducing anti-viral signal transduction pathways as well as inducing expression of inflammatory cytokines. We aimed to compare the induced inflammatory reactions in three keratinocyte cell types—normal human epidermal keratinocytes, the HaCaT cell line and the HPV-KER cell line—upon exposure to the synthetic RNA and DNA analogues poly(I:C) and poly(dA:dT) to reveal the underlying signaling events. Both agents induced the expression of interleukin-6 and tumor necrosis factor α in all cell types; however, notable kinetic and expression level differences were found. Western blot analysis revealed rapid activation of the nuclear factor κB (NF-κB), mitogen activated protein kinase and signal transducers of activator of transcription (STAT) signal transduction pathways in keratinocytes upon poly(I:C) treatment, while poly(dA:dT) induced slower activation. Inhibition of NF-κB, p38, STAT-1 and STAT-3 signaling resulted in decreased cytokine expression, whereas inhibition of mitogen-activated protein kinase kinase 1/2 (MEK1/2) signaling showed a negative feedback role in both poly(I:C)- and poly(dA:dT)-induced cytokine expression. Based on our in vitro results nucleotide fragments are able to induce inflammatory reactions in keratinocytes, but with different rate and kinetics of cytokine expression, explained by faster activation of signaling routes by poly(I:C) than poly(dA:dT). PMID:29518010

ATLAS FTK a - very complex - custom super computer

NASA Astrophysics Data System (ADS)

Kimura, N.; ATLAS Collaboration

2016-10-01

In the LHC environment for high interaction pile-up, advanced techniques of analysing the data in real time are required in order to maximize the rate of physics processes of interest with respect to background processes. The Fast TracKer (FTK) is a track finding implementation at the hardware level that is designed to deliver full-scan tracks with pT above 1 GeV to the ATLAS trigger system for events passing the Level-1 accept (at a maximum rate of 100 kHz). In order to achieve this performance, a highly parallel system was designed and currently it is being commissioned within in ATLAS. Starting in 2016 it will provide tracks for the trigger system in a region covering the central part of the ATLAS detector, and will be extended to the full detector coverage. The system relies on matching hits coming from the silicon tracking detectors against one billion patterns stored in custom ASIC chips (Associative memory chip - AM06). In a first stage, coarse resolution hits are matched against the patterns and the accepted hits undergo track fitting implemented in FPGAs. Tracks with pT > 1GeV are delivered to the High Level Trigger within about 100 ps. Resolution of the tracks coming from FTK is close to the offline tracking and it will allow for reliable detection of primary and secondary vertexes at trigger level and improved trigger performance for b-jets and tau leptons. This contribution will give an overview of the FTK system and present the status of commissioning of the system. Additionally, the expected FTK performance will be briefly described.

Health promotion--the rationale and the obstacles in workplaces with different employment and financial soundness.

PubMed

Puchalski, Krzysztof; Korzeniowska, Elzbieta

2013-01-01

This paper presents the prevalence of health promotion in workplaces in Poland. It characterises the undertaken ac tions, their rationale and perceived obstacles. It analyses the diversity of these phenomena in the companies of different financial soundness and level of employment. The study was conducted with the use of Computer Assisted Telephone Interview in 2010 on the representative national sample of 1002 workplaces hiring more than 50 employees. The data was compared with the results of the survey conducted in 2006, with the use of a Paper and Pencil interview on 611 similar companies. Both studies have shown that 40% of the companies are concerned about their employees' health to a greater extent than they are obliged to by the law. At the same time, more than 80% of the companies have been introducing various modifications and health-oriented actions without definite health intentions. Most companies improve their physical working environment, organise/sponsor medical services, sports activities and try to reduce stress and smoking. Managers have increased their awareness of business benefits re ceived from health promotion. They have displayed more personal involvement in health promotion implementation. The most often mentioned obstacles have included limited financial resources and little interest of employees regarding health issues. The larger and wealthier the company is, the more often health promotion in the company is performed. Such a company is more convinced about an increase in its activities and has more reasons to care about health. Unequal access to health promotion of wor kers in different companies may contribute to an increase in health inequalities in the working population.

Increased tree establishment in Lithuanian peat bogs--insights from field and remotely sensed approaches.

PubMed

Edvardsson, Johannes; Šimanauskienė, Rasa; Taminskas, Julius; Baužienė, Ieva; Stoffel, Markus

2015-02-01

Over the past century an ongoing establishment of Scots pine (Pinus sylvestris L.), sometimes at accelerating rates, is noted at three studied Lithuanian peat bogs, namely Kerėplis, Rėkyva and Aukštumala, all representing different degrees of tree coverage and geographic settings. Present establishment rates seem to depend on tree density on the bog surface and are most significant at sparsely covered sites where about three-fourth of the trees have established since the mid-1990s, whereas the initial establishment in general was during the early to mid-19th century. Three methods were used to detect, compare and describe tree establishment: (1) tree counts in small plots, (2) dendrochronological dating of bog pine trees, and (3) interpretation of aerial photographs and historical maps of the study areas. In combination, the different approaches provide complimentary information but also weigh up each other's drawbacks. Tree counts in plots provided a reasonable overview of age class distributions and enabled capturing of the most recently established trees with ages less than 50 years. The dendrochronological analysis yielded accurate tree ages and a good temporal resolution of long-term changes. Tree establishment and spread interpreted from aerial photographs and historical maps provided a good overview of tree spread and total affected area. It also helped to verify the results obtained with the other methods and an upscaling of findings to the entire peat bogs. The ongoing spread of trees in predominantly undisturbed peat bogs is related to warmer and/or drier climatic conditions, and to a minor degree to land-use changes. Our results therefore provide valuable insights into vegetation changes in peat bogs, also with respect to bog response to ongoing and future climatic changes. Copyright © 2014 Elsevier B.V. All rights reserved.

Mapping the emotional landscape: The role of specific emotions in conceptual categorization.

PubMed

Zhu, Nan; Cai, Yong-hua; Sun, Fa-wei; Yang-yang, Yi-fan

2015-07-01

Although researchers generally subscribe to the opinion that emotions play a critical role in cognition, very few (see Niedenthal, Halberstadt, & Innes-Ker, 1999) have examined the specific interaction between the emotional state of the perceiver and the emotional meaning of stimuli in conceptual categorization - an important aspect of "higher-level" cognition. Niedenthal et al. (1999) advanced a fine-grained theory of emotional response categorization, arguing that emotional states increase the tendency to categorize concepts into a predictable set of emotional response categories characterized by the common, distinct emotional responses elicited by the concepts. Based on the pioneering work of Niedenthal et al., we further argued that (1) the specific emotion experienced by the individual should selectively facilitate the categorization of concepts associated with the same emotion, (2) both in terms of category inclusion and category exclusion, and (3) this facilitation effect should not be contingent on the awareness of the emotional state. In three experiments, participants were induced to experience different emotional states through movies or a facial-feedback manipulation. They judged whether or not a target concept belonged to the same category as the two comparison concepts. Some of the concept triads shared emotional associations, while others didn't. Results showed that emotive participants had a greater tendency than those in a neutral mood to group concepts according to their emotional associations, and to distinguish concepts with different emotional associations. They were also more efficient in categorizing concepts that had specific emotional meaning corresponding to their own emotional state than to other emotional concepts. Furthermore, participants posing a disgust expression without their knowledge showed higher tendency to categorize concepts according to their relevance to disgust. Implications and potential applications of the findings were

Mechanistic Insights into Dye-Decolorizing Peroxidase Revealed by Solvent Isotope and Viscosity Effects

PubMed Central

Shrestha, Ruben; Huang, Gaochao; Meekins, David A.; Geisbrecht, Brian V.; Li, Ping

2017-01-01

Dye-decolorizing peroxidases (DyPs) are a family of H2O2-dependent heme peroxidases, which have shown potential applications in lignin degradation and valorization. However, the DyP kinetic mechanism remains underexplored. Using structural biology and solvent isotope (sKIE) and viscosity effects, many mechanistic characteristics have been uncovered for the B-class ElDyP from Enterobacter lignolyticus. Its structure revealed that a water molecule acts as the sixth axial ligand with two channels at diameters of ~3.0 and 8.0 Å leading to the heme center. A conformational change of ERS* to ERS, which have identical spectral characteristics, was proposed as the final step in DyPs’ bisubstrate Ping-Pong mechanism. This step is also the rate-determining step in ABTS oxidation. The normal KIE of wild-type ElDyP with D2O2 at pH 3.5 suggested that cmpd 0 deprotonation by the distal aspartate is rate-limiting in the formation of cmpd I, which is more reactive under acidic pH than under neutral or alkaline pH. The viscosity effects and other biochemical methods implied that the reducing substrate binds with cmpd I instead of the free enzyme. The significant inverse sKIEs of kcat/KM and kERS* suggested that the aquo release in DyPs is mechanistically important and may explain the enzyme’s adoption of two-electron reduction for cmpd I. The distal aspartate is catalytically more important than the distal arginine and plays key roles in determining DyPs’ acidic pH optimum. The kinetic mechanism of D143H-ElDyP was also briefly studied. The results obtained will pave the way for future protein engineering to improve DyPs’ lignolytic activity. PMID:29308295

Mechanistic Insights into Dye-Decolorizing Peroxidase Revealed by Solvent Isotope and Viscosity Effects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shrestha, Ruben; Huang, Gaochao; Meekins, David A.

Dye-decolorizing peroxidases (DyPs) are a family of H2O2-dependent heme peroxidases that have shown potential applications in lignin degradation and valorization. However, the DyP kinetic mechanism remains underexplored. Using structural biology and solvent isotope (sKIE) and viscosity effects, many mechanistic characteristics have been determined for the B-class ElDyP from Enterobacter lignolyticus. Its structure revealed that a water molecule acts as the sixth axial ligand and two channels at diameters of ~3.0 and 8.0 Å lead to the heme center. A conformational change of ERS* to ERS, which have identical spectral characteristics, was proposed as the final step in DyPs’ bisubstrate Ping-Pongmore » mechanism. This step is also the rate-determining step in ABTS oxidation. The normal KIE of wild-type ElDyP with D2O2 at pD 3.5 suggested that compound 0 deprotonation by the distal aspartate is rate-limiting in the formation of compound I, which is more reactive under acidic pH than under neutral or alkaline pH. The viscosity effects and other biochemical methods implied that the reducing substrate binds with compound I instead of the free enzyme. The significant inverse sKIEs of kcat/KM and kERS* suggested that the aquo release in ElDyP is mechanistically important and may explain the enzyme’s adoption of two-electron reduction for compound I. The distal aspartate is catalytically more important than the distal arginine and plays key roles in determining ElDyP’s optimum acidic pH. The kinetic mechanism of D143H-ElDyP was also briefly studied. The results obtained will pave the way for future protein engineering to improve DyPs’ lignolytic activity.« less

Microsecond Molecular Dynamics Simulations of Lipid Mixing

PubMed Central

2015-01-01

Molecular dynamics (MD) simulations of membranes are often hindered by the slow lateral diffusion of lipids and the limited time scale of MD. In order to study the dynamics of mixing and characterize the lateral distribution of lipids in converged mixtures, we report microsecond-long all-atom MD simulations performed on the special-purpose machine Anton. Two types of mixed bilayers, POPE:POPG (3:1) and POPC:cholesterol (2:1), as well as a pure POPC bilayer, were each simulated for up to 2 μs. These simulations show that POPE:POPG and POPC:cholesterol are each fully miscible at the simulated conditions, with the final states of the mixed bilayers similar to a random mixture. By simulating three POPE:POPG bilayers at different NaCl concentrations (0, 0.15, and 1 M), we also examined the effect of salt concentration on lipid mixing. While an increase in NaCl concentration is shown to affect the area per lipid, tail order, and lipid lateral diffusion, the final states of mixing remain unaltered, which is explained by the largely uniform increase in Na+ ions around POPE and POPG. Direct measurement of water permeation reveals that the POPE:POPG bilayer with 1 M NaCl has reduced water permeability compared with those at zero or low salt concentration. Our calculations provide a benchmark to estimate the convergence time scale of all-atom MD simulations of lipid mixing. Additionally, equilibrated structures of POPE:POPG and POPC:cholesterol, which are frequently used to mimic bacterial and mammalian membranes, respectively, can be used as starting points of simulations involving these membranes. PMID:25237736

Participation of D.O. Muhleman as a Co-Investigator on the Mars Observer Laser Altimeter (MOLA) Team

NASA Technical Reports Server (NTRS)

Muhleman, Duane O.

2004-01-01

The Co-I has been a principle member of the MOLA Team since the beginning of the Mars Observer Project and the MOLA Team formation. The basic area of research for the Co-I involved the interactions of the MOLA laser beam with the Mars atmosphere, ice fields and surface in general. The Co-I was assisted by one graduate student, and later a research assistant, Anton Ivanov, throughout the reporting period. Dr. Ivanov received a PhD from Caltech in 2000 from research involving the MOLA project. Dr. Ivanov continued with the MOLA project after receiving his degree as a research assistant to Professor Muhleman. Most of the funding from this grant was used to support Dr. Ivanov during the later years. The primary results of these investigations included the measurement of Mars atmospheric opacity at the 1 micron wavelength of the laser, the effects of dust within the craters and canyons of Mars, and a detailed study of the North Polar Ice Cap in terms of ice sublimation and the current structure of that ice cap. We were able to show that the sublimation of the ice on the polar cap would create the current average shape of the norther cap. Extensive data collection and study were made of the Mars surface 1 micron reflectivity until the laser mechanically failed during the reporting period. Reflectivity maps of Mars were produced although there were serious problems of the laser echo signal strength calibration. After that event the efforts were mainly to complete the older investigations. All of the work supported by this grant was theoretical in nature and did not lead to any patents.

Critical properties and high-pressure volumetric behavior of the carbon dioxide+propane system at T=308.15 k. Krichevskii function and related thermodynamic properties.

PubMed

Blanco, Sofía T; Gil, Laura; García-Giménez, Pilar; Artal, Manuela; Otín, Santos; Velasco, Inmaculada

2009-05-21

Critical properties and volumetric behavior for the {CO2(1)+C3H8(2)} system have been studied. The critical locus was measured with a flow apparatus and detected by critical opalescence. For the mixtures, repeatabilities in critical temperature and pressure are rTcAnton Paar DMA 512-P vibrating-tube densimeter calibrated with the forced path mechanical calibration model. The mean relative standard deviation of density, srhor, was estimated to be better than 0.1%, and the uncertainties in temperature and pressure are +/-0.01 K and +/-0.001 MPa, respectively. In the experimental setup, an uncertainty in the mole fraction, u(xj)=+/-0.0015, has been achieved. Other properties related to P-rho-T-x data such as saturated densities, rhoL and rhoV, compressibility factor, Z, excess molar volumes,VmE, and partial molar volumes, Vi, have been calculated. Structural properties such as direct and total correlation function integrals and cluster size were calculated using the Krichevskii function concept. Both the critical and volumetric behavior have been compared with literature data and with those obtained from the PC-SAFT and Patel-Teja equations of state.

[Medical cybernetics in Czechoslovakia--the first steps].

PubMed

Wünsch, Z

1998-09-01

During fifties there were at most few tens of persons in this country who believed in the future of computers and cybernetics. One group of such enthusiasts, headed by Antonín Svoboda, was working at a construction of the first Czech computer SAPO. The other group tried to analyse, anticipate, and prepare in advance various applications for the new systemic conceptions and for the information processing machines. Members of both groups met for discussions which opened prospects to the future and influenced many of other activities for a long time. At the early sixties, the Czechoslovak Cybernetic Society was established at the Czechoslovak Academy of Sciences and in 1962 the Main Problem Committee for the Medical Cybernetics was founded at the Department of Health. It coordinated majority of the research programmes in the medical cybernetics and informatics. In 1967-1969 the Committee prepared an extensive project of a medical information system (ZIS), but its accomplishment was finally blocked by the then authorities. However, interests for that topics kept growing and the new working places equipped with available computer technology were formed at the health and clinical centres. The first tentative lectures in medical cybernetics and biocybernetics at our faculty were introduced into the students curricula in the late sixties. Thematically, medical cybernetics subsequently differentiated into the medical informatics, simulations of biological and medical systems, and the biosignal analysis. The growing interest enabled to hold conferences since the middle of seventies, some of which were held periodically, sometimes with international participation. It is not possible in brevity to include the whole spectrum to those goal-directed activities nor to appraise adequately their future significance.

Modeling and Assessing Insect Disturbance on Boreal Forests in the Krasnoyarsk region of Russia by Employing the FAREAST Gap Model and Local Forest Inventory and Disturbance Data.

NASA Astrophysics Data System (ADS)

Erler, A. E.; Shuman, J. K.; Soukhavolosky, V.; Kovalev, A.; Stevens, T.; Shugart, H. H.

2008-12-01

FAREAST: an individual-based forest dynamics model was initially developed to simulate the forested region around Changbai Mountain in northern China. In recent years the model has been expanded across Siberia. The model output for biomass (tCha-1) has been verified against forest inventory data for a number of sites across Russia. With this success, an additional module for the model was written by Anton Kovalev to predict the impact of insect disturbance on the Boreal forests. This model predicts the probability of an insect outbreak occurring, and then, by assessing each individual tree in a modeled stand, predicts whether a tree will be killed as a result of insect predation. From this, a disturbance index is calculated that includes lost biomass as a result of insect disturbance and subsequent species composition. This disturbance "fingerprint" is being compared to forest inventory and insect disturbance data from the Usolsky forests in the Krasnoyarsk region of central Siberia. Silkworm disturbance is expressed in this geo- database as a percentage of trees damaged or killed in a stand. The forest inventory data allows us to calculate a biomass estimate that will be compared to the biomass outputs generated by the model post insect disturbance. The validation of simulated biomass with independent inventory data confirms that FAREAST is a robust model of Russian forest dynamics. Effective validation of the insect disturbance model will allow us to generate a more complete picture of the changing ecology of the Siberian Boreal landscape. The economic cost of lumber lost as a result of Silkworm damage has been enormous, if verified, FAREAST will afford us the opportunity to estimate the extent of that loss and predict the changing ecological dynamics of the Boreal forest system under the worlds evolving climate.

Applications and Implications of Fractional Dynamics for Dielectric Relaxation

NASA Astrophysics Data System (ADS)

Hilfer, R.

This article summarizes briefly the presentation given by the author at the NATO Advanced Research Workshop on "Broadband Dielectric Spectroscopy and its Advanced Technological Applications", held in Perpignan, France, in September 2011. The purpose of the invited presentation at the workshop was to review and summarize the basic theory of fractional dynamics (Hilfer, Phys Rev E 48:2466, 1993; Hilfer and Anton, Phys Rev E Rapid Commun 51:R848, 1995; Hilfer, Fractals 3(1):211, 1995; Hilfer, Chaos Solitons Fractals 5:1475, 1995; Hilfer, Fractals 3:549, 1995; Hilfer, Physica A 221:89, 1995; Hilfer, On fractional diffusion and its relation with continuous time random walks. In: Pekalski et al. (eds) Anomalous diffusion: from basis to applications. Springer, Berlin, p 77, 1999; Hilfer, Fractional evolution equations and irreversibility. In: Helbing et al. (eds) Traffic and granular flow'99. Springer, Berlin, p 215, 2000; Hilfer, Fractional time evolution. In: Hilfer (ed) Applications of fractional calculus in physics. World Scientific, Singapore, p 87, 2000; Hilfer, Remarks on fractional time. In: Castell and Ischebeck (eds) Time, quantum and information. Springer, Berlin, p 235, 2003; Hilfer, Physica A 329:35, 2003; Hilfer, Threefold introduction to fractional derivatives. In: Klages et al. (eds) Anomalous transport: foundations and applications. Wiley-VCH, Weinheim, pp 17-74, 2008; Hilfer, Foundations of fractional dynamics: a short account. In: Klafter et al. (eds) Fractional dynamics: recent advances. World Scientific, Singapore, p 207, 2011) and demonstrate its relevance and application to broadband dielectric spectroscopy (Hilfer, J Phys Condens Matter 14:2297, 2002; Hilfer, Chem Phys 284:399, 2002; Hilfer, Fractals 11:251, 2003; Hilfer et al., Fractional Calc Appl Anal 12:299, 2009). It was argued, that broadband dielectric spectroscopy might be useful to test effective field theories based on fractional dynamics.

Determination of osmium concentrations and (187)Os/(188)Os of crude oils and source rocks by coupling high-pressure, high-temperature digestion with sparging OsO(4) into a multicollector inductively coupled plasma mass spectrometer.

PubMed

Sen, Indra S; Peucker-Ehrenbrink, Bernhard

2014-03-18

The (187)Os/(188)Os ratio that is based on the β(-)-decay of (187)Re to (187)Os (t1/2 = 41.6 billion years) is widely used to investigate petroleum system processes. Despite its broad applicability to studies of hydrocarbon deposits worldwide, a suitable matrix-matched reference material for Os analysis does not exist. In this study, a method that enables Os isotope measurement of crude oil with in-line Os separation and purification from the sample matrix is proposed. The method to analyze Os concentration and (187)Os/(187)Os involves sample digestion under high pressure and high temperature using a high pressure asher (HPA-S, Anton Paar), sparging of volatile osmium tetroxide from the sample solution, and measurements using multicollector inductively coupled plasma mass spectrometry (MC-ICPMS). This methods significantly reduced the total procedural time compared to conventional Carius tube digestion followed by Os separation and purification using solvent extraction, microdistillation and N-TIMS analysis. The method yields Os concentration (28 ± 4 pg g(-1)) and (187)Os/(188)Os (1.62 ± 0.15) of commercially available crude oil reference material NIST 8505 (1 S.D., n = 6). The reference material NIST 8505 is homogeneous with respect to Os concentration at a test portion size of 0.2 g. Therefore, (187)Os/(188)Os composition and Os concentration of NIST 8505 can serve as a matrix-matched reference material for Os analysis. Data quality was assessed by repeated measurements of the USGS shale reference material SCo-1 (sample matrix similar to petroleum source rock) and the widely used Liquid Os Standard solution (LOsSt). The within-laboratory reproducibility of (187)Os/(188)Os for a 5 pg of LOsSt solution, analyzed with this method over a period of 12 months was ∼1.4% (1 S.D., n = 26), respectively.

DynAMo: A Modular Platform for Monitoring Process, Outcome, and Algorithm-Based Treatment Planning in Psychotherapy.

PubMed

Kaiser, Tim; Laireiter, Anton Rupert

2017-07-20

, Anton Rupert Laireiter. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 20.07.2017.

PREFACE: Eurotherm Seminar 102: Thermal Management of Electronic Systems

NASA Astrophysics Data System (ADS)

Punch, J.; Walsh, E.

2014-07-01

About EUROTHERM The aim of the EUROTHERM Committee (www.eurothermcommittee.eu) is to promote and foster European cooperation in Thermal Sciences and Heat Transfer by gathering together scientists and engineers working in specialized areas. The Committee consists of members representing and appointed by national bodies in the EU countries. The current President of EUROTHERM is Professor Anton van Steenhoven from the University of Eindhoven (The Netherlands). The Committee organizes and coordinates European scientific events such as the EUROTHERM Seminars (about 4 per year) and the European Thermal Sciences Conference (every 4 years). About EUROTHERM Seminar 102 (www.eurothermseminar102.com) This seminar, part of the long-running series of European seminars on the thermal sciences, took place in June 2014 at the University of Limerick in Limerick, Ireland. The seminar addressed the topic of 'Thermal Management of Electronic Systems', a critical contemporary application area which represents a vibrant challenge for practitioners of the thermal sciences. We convey special thanks to the reviewers who have evaluated these papers. We also thank the scientific committee, consisting of internationally recognized experts. Their role has been to manage the evaluation of abstracts and the papers selection process as co-coordinators for specific topics. This seminar was hosted by the Stokes Institute at the University of Limerick. It could not have been organized without the efficient help of our administrators and technicians for IT support. This volume of Journal of Physics: Conference Series includes 27 articles presented at the seminar. Dr. Jeff Punch, Chair Stokes Institute, University of Limerick, Limerick, Ireland Email: jeff.punch@ul.ie Prof. Edmond Walsh, Co-Chair Associate Professor, Osney Laboratories, Department of Engineering Science, University of Oxford, UK Email: edmond.walsh@bnc.ox.ac.uk

PREFACE: 6th European Thermal Sciences Conference (Eurotherm 2012)

NASA Astrophysics Data System (ADS)

Petit, Daniel; Le Niliot, Christophe

2012-11-01

About EUROTHERM The aim of the EUROTHERM Committee (www.eurothermcommittee.eu) is to promote and foster European cooperation in Thermal Sciences and Heat Transfer by gathering together scientists and engineers working in specialized areas. The Committee consists of members representing and appointed by national bodies in the EU countries. The current President of EUROTHERM is Professor Anton van Steenhoven from the University of Eindhoven (The Netherlands). The Committee organizes and coordinates European scientific events such as the EUROTHERM Seminars (about 4 per year) and the European Thermal Sciences Conference (every 4 years). About the conference This sixth in the series of European Thermal Sciences Conferences (www.eurotherm2012.com) took place in France, in the Conference Centre of Poitiers, Futuroscope. We address special thanks to the 225 reviewers, coming from different European countries, who have evaluated these papers. We also thank the scientific committee, consisting of some EUROTHERM Committee members together with other internationally recognized experts. Their role has been to manage the evaluation of abstracts and the papers selection process as co-coordinators for specific topics. This conference is the joint effort of two laboratories: the PPRIME Institute in Poitiers and the IUSTI laboratory in Marseille. It could not be organized without the efficient help of our secretaries and our technician for the IT support. This volume of Journal of Physics: Conference Series includes 180 articles presented at the conference. Professor Daniel PETIT Chairman, PPRIME Poitiers, France Institut P'(UPR CNRS 3346) ENSMA 1 av. Clément Ader - BP40109 86961 Futuroscope-Chasseneuil France daniel.petit@ensma.fr Professor Christophe LE NILIOT Co-chairman, IUSTI Marseille, France Laboratoire IUSTI UMR CNRS 6595 Technopôle de Chateau-Gombert 5, rue Enrico Fermi 13 453 MARSEILLE CEDEX 13 France christophe.leniliot@polytech.univ-mrs.fr

Feasibility study of entrance and exit dose measurements at the contra lateral breast with alanine/electron spin resonance dosimetry in volumetric modulated radiotherapy of breast cancer

NASA Astrophysics Data System (ADS)

Wagner, Daniela M.; Hüttenrauch, Petra; Anton, Mathias; von Voigts-Rhetz, Philip; Zink, Klemens; Wolff, Hendrik A.

2017-07-01

The Physikalisch-Technische Bundesanstalt has established a secondary standard measurement system for the dose to water, D W, based on alanine/ESR (Anton et al 2013 Phys. Med. Biol. 58 3259-82). The aim of this study was to test the established measurement system for the out-of-field measurements of inpatients with breast cancer. A set of five alanine pellets were affixed to the skin of each patient at the contra lateral breast beginning at the sternum and extending over the mammilla to the distal surface. During 28 fractions with 2.2 Gy per fraction, the accumulated dose was measured in four patients. A cone beam computer tomography (CBCT) scan was generated for setup purposes before every treatment. The reference CT dataset was registered rigidly and deformably to the CBCT dataset for 28 fractions. To take the actual alanine pellet position into account, the dose distribution was calculated for every fraction using the Acuros XB algorithm. The results of the ESR measurements were compared to the calculated doses. The maximum dose measured at the sternum was 19.9 Gy  ±  0.4 Gy, decreasing to 6.8 Gy  ±  0.2 Gy at the mammilla and 4.5 Gy  ±  0.1 Gy at the distal surface of the contra lateral breast. The absolute differences between the calculated and measured doses ranged from  -1.9 Gy to 0.9 Gy. No systematic error could be seen. It was possible to achieve a combined standard uncertainty of 1.63% for D W  =  5 Gy for the measured dose. The alanine/ESR method is feasible for in vivo measurements.

Premotor activations in response to visually presented single letters depend on the hand used to write: a study on left-handers.

PubMed

Longcamp, Marieke; Anton, Jean-Luc; Roth, Muriel; Velay, Jean-Luc

2005-01-01

In a previous fMRI study on right-handers (Rhrs), we reported that part of the left ventral premotor cortex (BA6) was activated when alphabetical characters were passively observed and that the same region was also involved in handwriting [Longcamp, M., Anton, J. L., Roth, M., & Velay, J. L. (2003). Visual presentation of single letters activates a premotor area involved in writing. NeuroImage, 19, 1492-1500]. We therefore suggested that letter-viewing may induce automatic involvement of handwriting movements. In the present study, in order to confirm this hypothesis, we carried out a similar fMRI experiment on a group of left-handed subjects (Lhrs). We reasoned that if the above assumption was correct, visual perception of letters by Lhrs might automatically activate cortical motor areas coding for left-handed writing movements, i.e., areas located in the right hemisphere. The visual stimuli used here were either single letters, single pseudoletters, or a control stimulus. The subjects were asked to watch these stimuli attentively, and no response was required. The results showed that a ventral premotor cortical area (BA6) in the right hemisphere was specifically activated when Lhrs looked at letters and not at pseudoletters. This right area was symmetrically located with respect to the left one activated under the same circumstances in Rhrs. This finding supports the hypothesis that visual perception of written language evokes covert motor processes. In addition, a bilateral area, also located in the premotor cortex (BA6), but more ventrally and medially, was found to be activated in response to both letters and pseudoletters. This premotor region, which was not activated correspondingly in Rhrs, might be involved in the processing of graphic stimuli, whatever their degree of familiarity.

Correlation between Organic Matter Degradation and the Rheological Performance of Waste Sludge During Anaerobic Digestion

NASA Astrophysics Data System (ADS)

Morel, Evangelina S.; Hernández-Hernándes, José A.; Méndez-Contreras, Juan M.; Cantú-Lozano, Denis

2008-07-01

Anaerobic digestion has demonstrated to be a good possibility to reduce the organic matter contents in waste activated sludge resulting in the effluents treatment. An anaerobic digestion was carried out in a 3.5 L reactor at 35 °C for a period of 20 days. An electronic thermostat controlled the temperature. The reactor was agitated at a rate of 200 rpm. The study of the rheological behavior of the waste activated sludge was done with an Anton Paar™ rheometer model MCR301 with a peltier plate for temperature control. Four-blade vane geometry was used with samples of 37 mL for determining rheological properties. Sampling (two samples) was taken every four days of anaerobic digestion through a peristaltic pump. The samples behavior was characterized by the Herschel-Bulkley model, with R2>0.99 for most cases. In all samples were found an apparent viscosity (ηap) and yield stress (τo) decrement when organic matter content diminishes. This demonstrates a relationship between rheological properties and organic matter concentration (% volatile solids). Also the flow activation energy (Ea) was calculated using the Ahrrenius correlation and samples of waste activated sludge before anaerobic digestion. In this case, samples were run in the rheometer at 200 rpm and a temperature range of 25 to 75 °C with an increment rate of 2 °C per minute. The yield stress observed was in a range of 0.93-0.18 Pa, the apparent viscosity was in a range of 0.0358-0.0010 Pa.s, the reduction of organic matter was in a range of 62.57-58.43% volatile solids and the average flow activation energy was 1.71 Calṡg-mol-1.

The Works of Henry Moseley, 1887-1915

NASA Astrophysics Data System (ADS)

Scerri, Eric

2013-04-01

In 1913 Henry Moseley, an unknown young English physicist published an article in the Philosophical Magazine under the title of ``The High Frequency Spectra of the Elements.'' The 10-page article was to have far reaching implications in both chemistry and physics and helped to resolve a major conundrum in the periodic table of the elements. The talk will briefly examine the life and work of Moseley who died tragically while fighting in the trenches of World War I in 1915. The build-up to the discovery of atomic number took several different avenues including contributions from Rutherford and Barkla. However the more direct motivation for Moseley's work, as he readily acknowledged, were the articles of an unknown Dutch econometrician Anton Van den Broek who attempted to improve on Mendeleev's periodic table. Moseley began as a student of Rutherford at Manchester and took a keen interest in the development of research using X-rays following the work of Roentgen, von Laue and Bragg. Although Rutherford was at first reluctant to enter this new field he soon yielded to young Moseley's request and sent him to Leeds for brief training with Bragg. On returning to Manchester, Moseley devised an ingenious apparatus in which a set of metal samples could be rotated so as to become the target for a beam of electrons in order to measure the frequencies of the emitted K X-rays. The first set of such experiments used nine successive elements in the periodic table, from titanium to zinc. Moseley's now immense fame rests with the results of this study as well as a subsequent one which extended the study into a further 30 elements, in addition to the use that his method was put to by himself as well as subsequent chemists and physicists.

Changes in visual and sensory-motor resting-state functional connectivity support motor learning by observing.

PubMed

McGregor, Heather R; Gribble, Paul L

2015-07-01

Motor learning occurs not only through direct first-hand experience but also through observation (Mattar AA, Gribble PL. Neuron 46: 153-160, 2005). When observing the actions of others, we activate many of the same brain regions involved in performing those actions ourselves (Malfait N, Valyear KF, Culham JC, Anton JL, Brown LE, Gribble PL. J Cogn Neurosci 22: 1493-1503, 2010). Links between neural systems for vision and action have been reported in neurophysiological (Strafella AP, Paus T. Neuroreport 11: 2289-2292, 2000; Watkins KE, Strafella AP, Paus T. Neuropsychologia 41: 989-994, 2003), brain imaging (Buccino G, Binkofski F, Fink GR, Fadiga L, Fogassi L, Gallese V, Seitz RJ, Zilles K, Rizzolatti G, Freund HJ. Eur J Neurosci 13: 400-404, 2001; Iacoboni M, Woods RP, Brass M, Bekkering H, Mazziotta JC, Rizzolatti G. Science 286: 2526-2528, 1999), and eye tracking (Flanagan JR, Johansson RS. Nature 424: 769-771, 2003) studies. Here we used a force field learning paradigm coupled with resting-state fMRI to investigate the brain areas involved in motor learning by observing. We examined changes in resting-state functional connectivity (FC) after an observational learning task and found a network consisting of V5/MT, cerebellum, and primary motor and somatosensory cortices in which changes in FC were correlated with the amount of motor learning achieved through observation, as assessed behaviorally after resting-state fMRI scans. The observed FC changes in this network are not due to visual attention to motion or observation of movement errors but rather are specifically linked to motor learning. These results support the idea that brain networks linking action observation and motor control also facilitate motor learning. Copyright © 2015 the American Physiological Society.

Changes in visual and sensory-motor resting-state functional connectivity support motor learning by observing

PubMed Central

McGregor, Heather R.

2015-01-01

Motor learning occurs not only through direct first-hand experience but also through observation (Mattar AA, Gribble PL. Neuron 46: 153–160, 2005). When observing the actions of others, we activate many of the same brain regions involved in performing those actions ourselves (Malfait N, Valyear KF, Culham JC, Anton JL, Brown LE, Gribble PL. J Cogn Neurosci 22: 1493–1503, 2010). Links between neural systems for vision and action have been reported in neurophysiological (Strafella AP, Paus T. Neuroreport 11: 2289–2292, 2000; Watkins KE, Strafella AP, Paus T. Neuropsychologia 41: 989–994, 2003), brain imaging (Buccino G, Binkofski F, Fink GR, Fadiga L, Fogassi L, Gallese V, Seitz RJ, Zilles K, Rizzolatti G, Freund HJ. Eur J Neurosci 13: 400–404, 2001; Iacoboni M, Woods RP, Brass M, Bekkering H, Mazziotta JC, Rizzolatti G. Science 286: 2526–2528, 1999), and eye tracking (Flanagan JR, Johansson RS. Nature 424: 769–771, 2003) studies. Here we used a force field learning paradigm coupled with resting-state fMRI to investigate the brain areas involved in motor learning by observing. We examined changes in resting-state functional connectivity (FC) after an observational learning task and found a network consisting of V5/MT, cerebellum, and primary motor and somatosensory cortices in which changes in FC were correlated with the amount of motor learning achieved through observation, as assessed behaviorally after resting-state fMRI scans. The observed FC changes in this network are not due to visual attention to motion or observation of movement errors but rather are specifically linked to motor learning. These results support the idea that brain networks linking action observation and motor control also facilitate motor learning. PMID:25995349

75 FR 71648 - Federal Motor Vehicle Safety Standards, Child Restraint Systems; Hybrid III 10-Year-Old Child...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-24

...This document proposes to amend Federal Motor Vehicle Safety Standard (FMVSS) No. 213, Child Restraint Systems, regarding a Hybrid III 10-year-old child test dummy that the agency seeks to use in the compliance test procedures of the standard. This document supplements a 2005 notice of proposed rulemaking (NPRM) and a 2008 SNPRM previously published in this rulemaking (RIN 2127-AJ44) regarding this test dummy. In the 2005 NPRM, in response to Anton's Law, NHTSA proposed to adopt the 10-year-old child test dummy into FMVSS No. 213 to test child restraints for older children. Subsequently, to address variation that was found in dummy readings due to chin-to-chest contact, NHTSA published the 2008 SNPRM to propose a NHTSA-developed procedure for positioning the test dummy in belt-positioning seats. Comments on the SNPRM objected to the positioning procedure, and some suggested an alternative procedure developed by the University of Michigan Transportation Research Institute (UMTRI). Today's SNPRM proposes to use the UMTRI procedure to position the test dummy rather than the NHTSA-developed procedure. We note that the 10-year-old child dummy may sometimes experience stiff contact between its chin and upper sternal bib region which may result in an unrealistically high value of the head injury criterion (HIC) \\1\\ referenced in the standard. Accordingly, NHTSA proposes that the dummy's HIC measurement will not be used to assess the compliance of the tested child restraint. This SNPRM also proposes other amendments to FMVSS No. 213, including a proposal to permit NHTSA to use, at the manufacturer's option, the Hybrid II or Hybrid III versions of the 6-year-old test dummy, and a proposal to use the UMTRI procedure to position the Hybrid III 6-year- old and 10-year-old dummies when testing belt-positioning seats. ---------------------------------------------------------------------------

Elongational flow of polymer melts at constant strain rate, constant stress and constant force

NASA Astrophysics Data System (ADS)

Wagner, Manfred H.; Rolón-Garrido, Víctor H.

2013-04-01

Characterization of polymer melts in elongational flow is typically performed at constant elongational rate or rarely at constant tensile stress conditions. One of the disadvantages of these deformation modes is that they are hampered by the onset of "necking" instabilities according to the Considère criterion. Experiments at constant tensile force have been performed even more rarely, in spite of the fact that this deformation mode is free from necking instabilities and is of considerable industrial relevance as it is the correct analogue of steady fiber spinning. It is the objective of the present contribution to present for the first time a full experimental characterization of a long-chain branched polyethylene melt in elongational flow. Experiments were performed at constant elongation rate, constant tensile stress and constant tensile force by use of a Sentmanat Extensional Rheometer (SER) in combination with an Anton Paar MCR301 rotational rheometer. The accessible experimental window and experimental limitations are discussed. The experimental data are modelled by using the Wagner I model. Predictions of the steady-start elongational viscosity in constant strain rate and creep experiments are found to be identical, albeit only by extrapolation of the experimental data to Hencky strains of the order of 6. For constant stress experiments, a minimum in the strain rate and a corresponding maximum in the elongational viscosity is found at a Hencky strain of the order of 3, which, although larger than the steady-state value, follows roughly the general trend of the steady-state elongational viscosity. The constitutive analysis also reveals that constant tensile force experiments indicate a larger strain hardening potential than seen in constant elongation rate or constant tensile stress experiments. This may be indicative of the effect of necking under constant elongation rate or constant tensile stress conditions according to the Considère criterion.

Observations of V420 Aur (HD 34921) needed to support spectroscopy

NASA Astrophysics Data System (ADS)

Waagen, Elizabeth O.

2016-10-01

Marcella Wijngaarden and Kelly Gourdji (graduate students at the University of Amsterdam/Anton Pannekoek Institute for Astronomy) have requested AAVSO observers' assistance in providing optical photometry of V420 Aur in support of their high-resolution spectroscopy with the Mercator telescope + Hermes spectrograph in La Palma 2016 October 7 through 17. They write: "[V420 Aur (HD 34921) is] the optical Be star that is part of a peculiar High Mass X-ray Binary...[that exhibits highly] complex and variable spectra...it is difficult to construct a physical model of this HMXB system, though based on these observations, the system is thought to contain a B[e] star with a dense plasma region, an accretion disk around a neutron star, a shell and circumstellar regions of cold dust. It has been over a decade since the last spectra were taken, and, given the highly variable nature of this star, we expect new observations to yield new information that will contribute to a better understanding of this system." Observations in BVRI (preferred over other bands) are requested beginning immediately and continuing through October 24. In all cases, timeseries in a few bands (i.e. BVRI) are preferred over single/a few observations in the other bands as it is the variability on relatively short timescales that is most important. "The target is bright so exposures should be long enough to reach good signal to noise in order to see the small variability amplitude but without saturating the target/comparison stars. We will study the variability on several timescales, so observations starting from a few per night to high cadence timeseries are useful." Finder charts with sequence may be created using the AAVSO Variable Star Plotter (https://www.aavso.org/vsp). Observations should be submitted to the AAVSO International Database. See full Alert Notice for more details.

2',3-dihydroxy-5-methoxybiphenyl suppresses fMLP-induced superoxide anion production and cathepsin G release by targeting the β-subunit of G-protein in human neutrophils.

PubMed

Liao, Hsiang-Ruei; Chen, Ih-Sheng; Liu, Fu-Chao; Lin, Shinn-Zhi; Tseng, Ching-Ping

2018-06-15

This study investigates the effect and the underlying mechanism of 2',3-dihydroxy-5-methoxybiphenyl (RIR-2), a lignan extracted from the roots of Rhaphiolepis indica (L.) Lindl. ex Ker var. tashiroi Hayata ex Matsum. & Hayata (Rosaceae), on N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP)-induced respiratory burst and cathepsin G in human neutrophils. Signaling pathways regulated by RIR-2 which modulated fMLP-induced respiratory burst were evaluated by an interaction between β subunit of G-protein (Gβ) with downstream signaling induced by fMLP and by immunoblotting analysis of the downstream targets of Gβ-protein. RIR-2 inhibited fMLP-induced superoxide anion production (IC 50 :2.57 ± 0.22 μM), cathepsin G release (IC 50 :18.72 ± 3.76 μM) and migration in a concentration dependent manner. RIR-2 specifically suppresses fMLP-induced Src family kinases phosphorylation by inhibiting the interaction between Gβ-protein with Src kinases without inhibiting Src kinases activities, therefore, RIR-2 attenuated the downstream targets of Src kinase, such as phosphorylation of Raf/ERK, AKT, P38, PLCγ2, PKC and translocation Tec, p47 ph ° x and P40 ph ° x from the cytosol to the inner leaflet of the plasma membrane. Furthermore, RIR-2 attenuated fMLP-induced intracellular calcium mobilization by inhibiting the interaction between Gβ-protein with PLCβ2. RIR-2 was not a competitive or allosteric antagonist of fMLP. On the contrary, phorbol 12-myristate 13-acetate (PMA)-induced phosphorylation of Src, AKT, P38, PKC and membrane localization of p47 ph ° x and P40 ph ° x remained unaffected. RIR-2 specifically modulates fMLP-mediated neutrophil superoxide anion production and cathepsin G release by inhibiting the interaction between Gβ-protein with downstream signaling which subsequently interferes with the activation of intracellular calcium, PLCγ2, AKT, p38, PKC, ERK, p47 ph ° x and p40 phox . Copyright © 2018 Elsevier B.V. All rights reserved.

Impulse-Control Disorders in Parkinson's Disease: A Meta-Analysis and Review of Case-Control Studies.

PubMed

Molde, Helge; Moussavi, Yasaman; Kopperud, Stine Therese; Erga, Aleksander Hagen; Hansen, Anita Lill; Pallesen, Ståle

2018-01-01

Although several case-control studies on the prevalence of Impulse-Control Disorders (ICDs) in Parkinson's Disease (PD) have been conducted, no meta-analytic study on this topic has previously been published. Thus, knowledge about the overall prevalence rate of ICD in PD and factors that might moderate this relationship is lacking. Prevalence studies of ICDs in PD were identified by computer searches in the MEDLINE, PsycINFO, and Web of Science databases, covering the period from January 2000 to February 2017. Data for N  = 4,539, consisting of 2,371 PD patients and 2,168 healthy controls, representing 14 case-control studies were included. Estimation of the odds ratio ( OR ) of ICDs in PD compared to healthy controls was conducted using random-effects models. Mixed-effects models were applied in the moderator analysis of heterogeneity. Publication bias was estimated using a contour-enhanced funnel plot, the Rüker's test, and fail-safe N test for estimating the number of potential missing studies. Overall, the results showed significantly higher ratios for several ICDs in PD compared to healthy controls with the estimated overall OR s ranging between 2.07, 95% CI [1.26, 3.48], for having any ICDs, and 4.26, 95% CI [2.17, 8.36], for hypersexuality. However, the random-effects results for shopping were non-significant, though the fixed-effects model was significant ( OR  = 1.66, 95%CI [1.21, 2.27]). The testing of potential moderator variables of heterogeneity identified the following two variables that were both associated with increased risk: being medically treated for PD and disease duration. The results must be interpreted with some caution due to possible small-studies effect or publication bias. Individuals with PD seem to have a significantly greater risk of suffering from ICDs compared to healthy controls. Gambling, hypersexuality, eating, punding, and hobbying are all ICDs significantly associated with PDs being medically treated for PD.

Biochemical and Molecular Characterization of a Serine Keratinase from Brevibacillus brevis US575 with Promising Keratin-Biodegradation and Hide-Dehairing Activities

PubMed Central

Jaouadi, Nadia Zaraî; Rekik, Hatem; Badis, Abdelmalek; Trabelsi, Sahar; Belhoul, Mouna; Yahiaoui, Amina Benkiar; Aicha, Houda Ben; Toumi, Abdessatar; Bejar, Samir; Jaouadi, Bassem

2013-01-01

Dehairing is one of the highly polluting operations in the leather industry. The conventional lime-sulfide process used for dehairing produces large amounts of sulfide, which poses serious toxicity and disposal problems. This operation also involves hair destruction, a process that leads to increased chemical oxygen demand (COD), biological oxygen demand (BOD), and total suspended solid (TSS) loads in the effluent. With these concerns in mind, enzyme-assisted dehairing has often been proposed as an alternative method. The main enzyme preparations so far used involved keratinases. The present paper reports on the purification of an extracellular keratinase (KERUS) newly isolated from Brevibacillus brevis strain US575. Matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF/MS) analysis revealed that the purified enzyme was a monomer with a molecular mass of 29121.11 Da. The sequence of the 27 N-terminal residues of KERUS showed high homology with those of Bacillus keratinases. Optimal activity was achieved at pH 8 and 40°C. Its thermoactivity and thermostability were upgraded in the presence of 5 mM Ca2+. The enzyme was completely inhibited by phenylmethanesulfonyl fluoride (PMSF) and diiodopropyl fluorophosphates (DFP), which suggests that it belongs to the serine protease family. KERUS displayed higher levels of hydrolysis, substrate specificity, and catalytic efficiency than NUE 12 MG and KOROPON® MK EG keratinases. The enzyme also exhibited powerful keratinolytic activity that made it able to accomplish the entire feather-biodegradation process on its own. The kerUS gene encoding KERUS was cloned, sequenced, and expressed in Escherichia coli. The biochemical properties of the extracellular purified recombinant enzyme (rKERUS) were similar to those of native KERUS. Overall, the findings provide strong support for the potential candidacy of this enzyme as an effective and eco-friendly alternative to the conventional chemicals used

Kyasanur Forest Disease Prevalence in Western Ghats Proven and Confirmed by Recent Outbreak in Maharashtra, India, 2016.

PubMed

Gurav, Yogesh K; Yadav, Pragya D; Gokhale, Mangesh D; Chiplunkar, Tushar R; Vishwanathan, Rajlakshmi; Patil, Deepak Y; Jain, Rajlaxmi; Shete, Anita M; Patil, Savita L; Sarang, G D; Sapkal, Gajanan N; Andhare, M D; Sale, Y R; Awate, Pradeep S; Mourya, Devendra T

2018-03-01

Kyasanur forest disease (KFD) outbreak was confirmed in Dodamarg Taluka, Sindhudurga district (Maharashtra) in India during the year 2016. The rise in suspected KFD cases was reported in January 2016, peaked during March, and then declined gradually from April 2016. The outbreak was thoroughly investigated considering different socio-clinical parameters. Total, 488 suspected KFD cases were investigated using KFD specific real-time RT-PCR and anti-KFDV IgM enzyme-linked immunosorbent assay (ELISA). Sero-epidemiological survey was carried out in the affected area using anti-KFDV IgG ELISA. Among suspected KFD cases, high age-specific attack rate (105.1 per 1000 persons) was observed in adults (aged 40-59 years). Out of 488 suspected KFD cases, 130 were laboratory confirmed. Of these, 54 cases were KFDV real-time RT-PCR positive, 66 cases were anti-KFDV IgM ELISA positive and 10 cases were positive by both the assays. Case fatality ratio among laboratory-confirmed KFD cases were 2.3% (3/130). Majority of laboratory-confirmed KFD cases (93.1%) had visited Western Ghats forest in Dodamarg for activities like working in cashew nut farms (79.8%), cashew nut fruit collection (76.6%), collection of firewood (68.5%) and dry leaves/grass (40.3%), etc., before the start of symptoms. Common clinical features included fever (100%), headache (93.1%), weakness (84.6%), and myalgia (83.1%). Hemorrhagic manifestations were observed in nearly one-third of the laboratory-confirmed KFD cases (28.5%). A seroprevalence of (9.7%, 72/745) was recorded in KFD-affected area and two neighboring villages (9.1%, 15/165). Serosurvey conducted in Ker village showed clinical to subclinical ratio of 6:1 in KFD-affected areas. This study confirms the outbreak of KFD Sindhudurg district with 130 cases. Detection of anti-KFDV IgG antibodies among the healthy population in KFD-affected area during the KFD outbreak suggested the past exposure of KFD infection. This outbreak investigation has helped

Use of Information and Communication Technologies Among Older People With and Without Frailty: A Population-Based Survey.

PubMed

Keränen, Niina Susanna; Kangas, Maarit; Immonen, Milla; Similä, Heidi; Enwald, Heidi; Korpelainen, Raija; Jämsä, Timo

2017-02-14

Use of information and communication technologies (ICT) among seniors is increasing; however, studies on the use of ICT by seniors at the highest risk of health impairment are lacking. Frail and prefrail seniors are a group that would likely benefit from preventive nutrition and exercise interventions, both of which can take advantage of ICT. The objective of the study was to quantify the differences in ICT use, attitudes, and reasons for nonuse among physically frail, prefrail, and nonfrail home-dwelling seniors. This was a population-based questionnaire study on people aged 65-98 years living in Northern Finland. A total of 794 eligible individuals responded out of a contacted random sample of 1500. In this study, 29.8% (237/794) of the respondents were classified as frail or prefrail. The ICT use of frail persons was lower than that of the nonfrail ones. In multivariable logistic regression analysis, age and education level were associated with both the use of Internet and advanced mobile ICT such as smartphones or tablets. Controlling for age and education, frailty or prefrailty was independently related to the nonuse of advanced mobile ICT (odds ratio, OR=0.61, P=.01), and frailty with use of the Internet (OR=0.45, P=.03). The frail or prefrail ICT nonusers also held the most negative opinions on the usefulness or usability of mobile ICT. When opinion variables were included in the model, frailty status remained a significant predictor of ICT use. Physical frailty status is associated with older peoples' ICT use independent of age, education, and opinions on ICT use. This should be taken into consideration when designing preventive and assistive technologies and interventions for older people at risk of health impairment. ©Niina Susanna Keränen, Maarit Kangas, Milla Immonen, Heidi Similä, Heidi Enwald, Raija Korpelainen, Timo Jämsä. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 14.02.2017.

Ancient DNA analysis of 8000 B.C. near eastern farmers supports an early neolithic pioneer maritime colonization of Mainland Europe through Cyprus and the Aegean Islands.

PubMed

Fernández, Eva; Pérez-Pérez, Alejandro; Gamba, Cristina; Prats, Eva; Cuesta, Pedro; Anfruns, Josep; Molist, Miquel; Arroyo-Pardo, Eduardo; Turbón, Daniel

2014-06-01

The genetic impact associated to the Neolithic spread in Europe has been widely debated over the last 20 years. Within this context, ancient DNA studies have provided a more reliable picture by directly analyzing the protagonist populations at different regions in Europe. However, the lack of available data from the original Near Eastern farmers has limited the achieved conclusions, preventing the formulation of continental models of Neolithic expansion. Here we address this issue by presenting mitochondrial DNA data of the original Near-Eastern Neolithic communities with the aim of providing the adequate background for the interpretation of Neolithic genetic data from European samples. Sixty-three skeletons from the Pre Pottery Neolithic B (PPNB) sites of Tell Halula, Tell Ramad and Dja'de El Mughara dating between 8,700-6,600 cal. B.C. were analyzed, and 15 validated mitochondrial DNA profiles were recovered. In order to estimate the demographic contribution of the first farmers to both Central European and Western Mediterranean Neolithic cultures, haplotype and haplogroup diversities in the PPNB sample were compared using phylogeographic and population genetic analyses to available ancient DNA data from human remains belonging to the Linearbandkeramik-Alföldi Vonaldiszes Kerámia and Cardial/Epicardial cultures. We also searched for possible signatures of the original Neolithic expansion over the modern Near Eastern and South European genetic pools, and tried to infer possible routes of expansion by comparing the obtained results to a database of 60 modern populations from both regions. Comparisons performed among the 3 ancient datasets allowed us to identify K and N-derived mitochondrial DNA haplogroups as potential markers of the Neolithic expansion, whose genetic signature would have reached both the Iberian coasts and the Central European plain. Moreover, the observed genetic affinities between the PPNB samples and the modern populations of Cyprus and Crete

Ancient DNA Analysis of 8000 B.C. Near Eastern Farmers Supports an Early Neolithic Pioneer Maritime Colonization of Mainland Europe through Cyprus and the Aegean Islands

PubMed Central

Fernández, Eva; Pérez-Pérez, Alejandro; Gamba, Cristina; Prats, Eva; Cuesta, Pedro; Anfruns, Josep; Molist, Miquel; Arroyo-Pardo, Eduardo; Turbón, Daniel

2014-01-01

The genetic impact associated to the Neolithic spread in Europe has been widely debated over the last 20 years. Within this context, ancient DNA studies have provided a more reliable picture by directly analyzing the protagonist populations at different regions in Europe. However, the lack of available data from the original Near Eastern farmers has limited the achieved conclusions, preventing the formulation of continental models of Neolithic expansion. Here we address this issue by presenting mitochondrial DNA data of the original Near-Eastern Neolithic communities with the aim of providing the adequate background for the interpretation of Neolithic genetic data from European samples. Sixty-three skeletons from the Pre Pottery Neolithic B (PPNB) sites of Tell Halula, Tell Ramad and Dja'de El Mughara dating between 8,700–6,600 cal. B.C. were analyzed, and 15 validated mitochondrial DNA profiles were recovered. In order to estimate the demographic contribution of the first farmers to both Central European and Western Mediterranean Neolithic cultures, haplotype and haplogroup diversities in the PPNB sample were compared using phylogeographic and population genetic analyses to available ancient DNA data from human remains belonging to the Linearbandkeramik-Alföldi Vonaldiszes Kerámia and Cardial/Epicardial cultures. We also searched for possible signatures of the original Neolithic expansion over the modern Near Eastern and South European genetic pools, and tried to infer possible routes of expansion by comparing the obtained results to a database of 60 modern populations from both regions. Comparisons performed among the 3 ancient datasets allowed us to identify K and N-derived mitochondrial DNA haplogroups as potential markers of the Neolithic expansion, whose genetic signature would have reached both the Iberian coasts and the Central European plain. Moreover, the observed genetic affinities between the PPNB samples and the modern populations of Cyprus and

Exhumation History of the North Queensland Segment of Australia's Elevated Passive Margin Escarpment as Revealed by (U-Th)/He Analysis of Apatite and Zircon

NASA Astrophysics Data System (ADS)

Abbott, L. D.; Glass, J.; Flowers, R. M.; Metcalf, J. R.

2016-12-01

Australia's east coast constitutes an elevated passive continental margin that developed in response to Cretaceous-Paleogene rifting during opening of the Tasman and Coral seas. Typical of elevated passive margins around the world, Australia's east coast consists of a high plateau bounded by an abrupt escarpment, known as the Great Escarpment. We employed the apatite (AHe) and zircon (ZHe) (U-Th)/He low temperature thermochronometers to explore the exhumation history of the North Queensland segment of the Great Escarpment. Our 1500m vertical transect was conducted up the southeast flank of Mount Bartle Frere, which exposes the Bartle Frere pluton of the ca. 280 Ma Bellenden Ker Batholith. A previous apatite fission track (AFT) study determined that an outcrop of the Bartle Frere pluton at Josephine Falls, which constitutes the base of our transect, cooled through 110 °C at 142.3 ±9.9Ma. Our preliminary ZHe analysis of the same outcrop reveals that it passed through 180 °C at ca. 155 Ma. These data point to an episode of relatively rapid exhumation during the latest Jurassic to earliest Cretaceous, which brought the Bartle Frere pluton from approximately 6 km burial depth to 3.5 km depth (assuming a 30 °C/km geothermal gradient). Samples throughout our entire transect yield AHe dates that range between 72Ma and 182Ma, with no apparent elevation-date relationship. These data suggest that the pluton cooled below 65 °C during the Cretaceous, indicating unroofing to less than 2 km depth by that time. The data scatter makes it difficult to resolve the details of this Cretaceous cooling episode. However, the fact that we obtain Cretaceous AHe dates across the entire 1500 m height of the transect suggests that the Great Escarpment in North Queensland has existed at approximately its current location and height since at least the Late Cretaceous. The Cretaceous age for this segment of the Great Escarpment is similar to the age determined by other AHe workers for the

Local Heroes Live!

NASA Astrophysics Data System (ADS)

1999-09-01

Physics teacher Andrew Morrison from High Pavement College in Nottingham has recently been appointed as Schools' officer for particle physics by the Particle Physics and Astronomy Research Council, as part of the Council's Public Understanding of Science programme. As well as his role as an experienced physics teacher, Andrew has acted as marketing manager for his college and chair of the Nottinghamshire section of the Association for Science Education. He will now be working two days each week in his new role with PPARC, acting as a link between the science education and research communities, helping researchers develop ideas for promoting particle physics and leading some specific new projects for the production of schools materials. Andrew can be contacted at High Pavement Sixth Form College, Gainsford Crescent, Nottingham NG5 5HT (tel: 0115 916 6165 or e-mail: morrison@innotts.co.uk). On the other side of the Atlantic, an 18 year-old student at Atlee High School in Mechanicsville, Virginia, USA was the recipient of the `1999 Young Scientist of the Year' award. Jakob Harmon submitted a project on magnetic levitation (maglev) in this extracurricular competition organized by PhysLINK.com, a leading Internet authority on physics and engineering education. The prize was a summer placement at Virginia Polytechnic Institute, Blacksburg, where Jakob continued his education in one of the most active maglev research and development groups in the USA. He also received science books and software as part of the award. The PhysLINK.com award was established to recognize, encourage and foster talented high school students in physics and engineering, with the prize being designed to fit the specific needs and aspirations of each individual winner. Details of next year's competition, along with Jakob's project and more about magnetic levitation can be viewed at www.physlink.com or by contacting Anton Skorucak of PhysLINK.com at 11271 Ventura Blvd #299, Studio City, CA 91606

All-Manganite Tunnel Junctions with Interface-Induced Barrier Magnetism

NASA Astrophysics Data System (ADS)

Sefrioui, Zouhair

2011-03-01

The recent discovery of several unexpected phases at complex oxide interfaces is providing new insights into the physics of strongly correlated electron systems. The possibility of tailoring the electronic structure of such interfaces has triggered a great technological drive to functionalize them into devices. In this communication, we describe an alternative strategy to produce spin filtering by inducing a ferromagnetic insulating state in an ultrathin antiferromagnetic layer in contact with a ferromagnetic layer. This artificially induced spin filtering persists up to relatively high temperatures and operates at high applied bias voltages. The results suggest that after playing a key role in exchange-bias for spin-valves, uncompensated moments at engineered antiferromagnetic interfaces represent a novel route for generating highly spin-polarized currents with antiferromagnets. Work done in collaboration with M. Bibes, C. Carrétéro, A. Barthélémy (Unité Mixte de Physique CNRS/Thales, Campus de Polytechnique, 1, Avenue A. Fresnel, 91767 Palaiseau (France) and Université Paris-Sud, 91045 Orsay (France)), F.A. Cuellar, C. Visani, A. Rivera-Calzada, , C. León, J. Santamaria (Grupo de Física de Materiales Complejos, Universidad Complutense de Madrid, 28040 Madrid (Spain)), M.J. Calderón, L. Brey (Instituto de Ciencia de Materiales de Madrid, CSIC, Cantoblanco, 28049 Madrid (Spain)), K. March, M. Walls, D. Imhoff (Laboratoire de Physique des Solides, CNRS, Université Paris-Sud, 91405 Orsay (France)), R. Lopez Anton, T.R. Charlton (ISIS, Rutherford Appleton Laboratory, Chilton, Oxon OX11 0QX (United Kingdom)), E. Iborra (Universidad Politécnica de Madrid, Escuela Técnica Superior de Ingenieros de Telecomunicaciones, 28040 Madrid (Spain)), F. Ott (Léon Brillouin, CEA/CNRS, UMR 12, 91191 Gif-sur-Yvette (France)). This work was supported by the Spanish Ministry for Science and Education programs MAT2008 06517, and the Réseau Thématique de Recherche Avanc

The Physicist and Astronomer Christoper Scheiner - Biography Letters, Works

NASA Astrophysics Data System (ADS)

Daxecker, Franz

The Jesuit priest Christopher Scheiner was one of the most influential astronomers of the first half of the 17th century. He was a creative and down-to-earth natural scientist who worked in the fields of astronomy, physics, optics and ophthalmology, while following his vocations as university lecturer, church builder and pastor. In scientific matters he was Galilei's opponent. Their dispute centred on the priority of discovery in regard to the sunspots. Scheiner was not the first to discover the sunspots, but he gave the most detailed account thereofin his main work "Rosa Ursina sive Sol". He was, however, ceaseless in his defense of the geocentric system. In 1891, Anton v.Braunmühl published a biography of Father Scheiner. Ever since then, new documents have come to light, justifying the publication of a new biography. Among the documents now available is Scheiner's hitherto unknown dissertation. Notes taken during his lectures in Ingolstadt provide valuable information on astronomy using the telescope, an invention of his lifetime. His exchange of letters with personalities like Archduke Leopold V of Austria-Tyrol, with scientists like Magini, Galilei, Gassendi, Kepler and confriars Rader, Guldin, Alber, Minutuli, Cysat und Kircher is a source of precious insights. Letters to Scheiner from the Father Generals of his order display evidence of his superiors' zero tolerance for the helincentric system. They also disclose Scheiner's wish to become a missionary in China, the financial difficulties he faced while trying to find a publisher for his "Rosa Ursina sive Sol" and his personal shortcomings. A Scheiner obituary from 1650 was found in Cracow in 2001. It contains information on the troublesome last years of his life and has finally allowed us to determine the year of his birth. Scheiner's personality has been praised as well as criticized by many authors - sometimes depending on their ideological backgrounds. This holds true especially regarding the argument

VizieR Online Data Catalog: The Initial Gaia Source List (IGSL) (Smart, 2013)

NASA Astrophysics Data System (ADS)

Smart, R. L.; Nicastro, L.

2013-11-01

The IGSL is a compilation catalog produced for the Gaia mission. We have combined data from the following catalogs or datasets to produce a homogenous list of positons, proper motions, photometry in a blue and red band and estimates of the magnitudes in the Gaia G and G_RVS bands. Included Catalogs: Tycho2, LQRF, UCAC4, SDSS-DR9, PPMXL, GSC23, GEPC, OGLE, Sky2000, 2MASS. Note that in compiling the various entries we did not consider the individual flags. Overall, we think this catalog is reliable but there will be errors, mismatches and duplicates. The user should use this catalog with that in mind, it is fine for statistical studies that has some way to remove obviously incorrect entries but it should only be used with care for individual objects. The source catalogs used to produce the IGSL are: * The Gaia Ecliptic Pole Catalog, version 3.0 (GEPC) Altmann & Bastian 2009, "Ecliptic Poles Catalogue Version 1.1" ESA Document GAIA-C3-TN-ARI-MA-002 URL http://www.rssd.esa.int/llink/livelink/open/2885828 * GSC2.3: GSC2 version 2.3, Lasker et al. 2008AJ....136..735L (I/305) * an excerpt of the 4th version of the Gaia Initial QSO Catalog (GIQC) as compiled by the GWP-S-335-13000, formed by Alexandre H. Andrei, Christophe Barache, Dario N. da Silva Neto, Francois Taris, Geraldine Bourda, Jean-Francois Le Campion, Jean Souchay, J.J. Pereira Osorio, Julio I. Bueno de Camargo, Marcelo Assafin, Roberto Vieira Martins, Sebastien Bouquillon, Sebastien Lambert, Sonia Anton, Patrick Charlot * OGLE: Optical Gravitational Lensing Experiment version III (Szymaski et al., 2011, Cat. J/AcA/61/83) * PPMXL: Positions and Proper Motions "Extra Large" Catalog, Roeser et al. (2010, Cat. I/317) * SDSS: Sloan Digital Sky Survey data release 9, Cat. V/139 * UCAC4: Zacharias et al., 2012, Cat. I/322 * Tycho-2, Hoeg et al., 2000, Cat. I/259 (1 data file).

Viral Hepatitis Strategic Information to Achieve Elimination by 2030: Key Elements for HIV Program Managers.

PubMed

Hutin, Yvan; Low-Beer, Daniel; Bergeri, Isabel; Hess, Sarah; Garcia-Calleja, Jesus Maria; Hayashi, Chika; Mozalevskis, Antons; Rinder Stengaard, Annemarie; Sabin, Keith; Harmanci, Hande; Bulterys, Marc

2017-12-15

�Yvan Hutin, Daniel Low-Beer, Isabel Bergeri, Sarah Hess, Jesus Maria Garcia-Calleja, Chika Hayashi, Antons Mozalevskis, Annemarie Rinder Stengaard, Keith Sabin, Hande Harmanci, Marc Bulterys. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 15.12.2017.

Microgravity can activate signals urging cells to S-phase entry during tissue and organ regeneration in Urodele amphibians exposed to real and simulated microgravity

NASA Astrophysics Data System (ADS)

Grigoryan, E.; Anton, H.-J.; Mitashov, V.

Regenerative response following local injury or tissue removal in urodele amphibians is dependent on cell cycle entry of cells sources for regeneration in the remaining tissue. In a number of our experiments performed aboard biosatellites in orbital flights and fast rotated clinostat we found enhanced proliferative activity and, as a result, regeneration quicker than that in controls. In each investigated case an activity of cell proliferation evaluated by 3H-thymidine radioautography and BrdU assay at the early stages of lens, retina, forelimb and tail regeneration in newts was about 1,2-1,7 fold higher both under conditions of real and physiological weightlessness as compared with controls. Faster S-phase entry under conditions of micro- g was demonstrated by cycling multipotent cells as well as by differentiated postmitotic cells both participated in regeneration. Important, that cycling cells outside areas of regeneration were also found as displayed faster cellular growth. In our papers (1,2,3,4) we offered some hypothesis that could explain mechanisms of low g stimulating effect upon cell growth in regeneration in Urodela. In particular, changes in expression of some growth factors and their receptors, as well as the synthesis of specific range of generalized stress proteins (AGSPs) were proposed. However, in fact, molecular mechanisms of micro- g effect upon cell proliferation are mediated by changes on organismic level induced by micro- g environment. Some of them which are able to trigger off signaling changes on the cellular level that, in turn, evoke cells to grow faster would be represented in our report. 1. Mitashov V. et al. Adv. Space Res. 1996. 17 (6/7): 241-255 2. Anton H.-J. et al. Adv. Space Res. 1996. 17 (6/7): 55-65 3. Grigoryan E. et al. Adv. Space Res. 1998. 22 (2): 293-301 4. Grigoryan E. et al. Adv. Space Res. 2002. 30 (4): 757-764

PREFACE: 2nd International School and Conference Saint-Petersburg OPEN on Optoelectronics, Photonics, Engineering and Nanostructures (SPbOPEN2015)

NASA Astrophysics Data System (ADS)

2015-11-01

The 2nd International School and Conference ''Saint Petersburg OPEN 2015'' on Optoelectronics, Photonics, Engineering and Nanostructures was held on April 6 - 8, 2015 at St. Petersburg Academic University. The School and Conference included a series of invited talks given by leading professors with the aim to introduce young scientists with actual problems and major advances in physics and technology. The keynote speakers were Mikhail V. Maximov (Ioffe Physico-Technical Institute RAS, Russia) Vladimir G. Dubrovskii (St. Petersburg Academic University and St. Petersburg State University, Russia) Anton Yu. Egorov (JSC Connector Optics, Russia) Victor V. Luchinin (St. Petersburg State Electrotechnical University, Russia) Vladislav E. Bugrov (St. Petersburg University of Internet Technologies, Mechanics and Optics, Russia) Vitali A. Schukin (VI Systems, Germany) Yuri P. Svirko (University of Eastern Finland, Finland) During the poster session all undergraduate and graduate students attending the conference presented their works. A sufficiently large number of participants, with more than 170 student attendees from all over the world, allowed the Conference to provide a fertile ground for fruitful discussions between the young scientists as well as to become a perfect platform for valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers basing on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year ''Saint Petersburg OPEN 2015'' is organized by St. Petersburg Academic University in cooperation with Peter the Great St. Petersburg Polytechnic University. The School and Conference is supported by Russian Science Foundation, SPIE (The International Society for Optics and Photonics), OSA (The Optical Society) and by Skolkovo Foundation. It is a continuation of the annual schools and seminars for

Fragmentation of Small Molecules by Photo-Double Ionization

NASA Astrophysics Data System (ADS)

Osipov, Timur

2008-05-01

Molecular structure, formation, breakup pathways and recombination formed the subject of many theoretical and experimental studies. Among molecular species like H2, CO, N2, O2 recently great attention has been paid to the dynamics of the fragmentations and rearrangements of C2H2 molecule. Nature's smallest stable hydrocarbon, the symmetric linear acetylene molecule, C2H2, is an important polyatomic system for the study of photo initiated processes. Important features of the intramolecular dynamics in neutral acetylene have been revealed over many years through numerous spectroscopic studies. More recently, the availability of synchrotron radiation and intense laser sources has lead to intriguing studies of the ionization, isomerization and breakup dynamics of acetylene ions. Of particular interest are the yields into the symmetric (CH^+/CH^+), deprotonation (HCC^+/H^+) and quasi-symmetric (HHC^+/C^+) channels, the latter involving isomerization from the neutral acetylene structure into the vinylidene configuration prior to breakup. One expects that the products of dissociation, their kinetic energy releases (KER) and the isomerization times will depend on the particular initial electronic states of the dication involved, but such detailed information has heretofore not been available. We will present the results of the experiment where the dication of acetylene is prepared by Auger decay following core-level X-ray photoionization. Cold Target Recoil Ion Momentum Spectroscopy technique was used to measure the corresponding 3d momentum vectors of Auger electrons and recoil ions in coincidence. We will show that this experimental approach, in combination with ab initio quantum mechanical calculations, can yield a comprehensive map of the two-body dissociation pathways including transition through different electronic energy surfaces, barriers to direct dissociation and the associated rearrangement channels. Work done in collaboration with T. Rescigno, T. Weber, S

Deriving Equations of State for Specific Lakes and Inland Seas from Laboratory Measurements

NASA Astrophysics Data System (ADS)

Andrulionis, Natalia; Zavialov, Ivan; Zavialov, Peter; Osadchiev, Alexander; Kolokolova, Alexandra; Alukaeva, Alevtina; Izhitskiy, Alexander; Izhitskaya, Elena

2017-04-01

The equation of state is the dependence of water density on temperature, salinity, and pressure. It is important in many respects, in particular, for numerical modeling of marine systems. The widely used UNESCO equation of state, as well as the more recent and general TEOS-10 equation, are intended for the ocean waters. Hence, they are confined to salinities below 40 ‰ and, even more restrictively, valid only for ionic salt composition characteristic for the ocean. Both conditions do not hold for many lakes. Moreover, significant deviations of the ionic composition from the oceanic one have been documented for coastal zones, especially those exposed to river discharges. Therefore, the objective of this study was to find equations of state for areas or water bodies with non-oceanic ionic salt composition. In order to obtain the required equations, we analyzed water samples obtained in expeditions of 2014-2016 from the Black Sea, the Aral Sea, Lake Issyk-Kul and Caspian Sea. The filtered samples were submitted to high accuracy (up to 0.00001 g/cm3) density measurements in laboratory using the Anton Paar DMA 5000M in the temperature range from 1 to 29°C. The absolute salinity values of the initial samples were obtained through the dry residue method. Further, we diluted the samples by purified deionized water to produce different salinities. To control the accuracy of the dilution process, we used a reference sample of standard IAPSO-certified seawater at 35‰. The density versus salinity and temperature data obtained thereby were then approximated by a best fitting 2-order polynomial surface using the least squares method. This procedure yielded the approximate empirical equations of state for the selected marine areas (the Russian Black Sea shelf) and inland water bodies (the Aral Sea, the Lake Issyk-Kul, the Caspian Sea). The newly derived equations - even the one for the Black Sea shelf - are different from the oceanic equation significantly within the

[Electroconvulsive therapy and level of evidence: From causality to dose-effect relationship].

PubMed

Micoulaud-Franchi, J-A; Quilès, C; Cermolacce, M; Belzeaux, R; Adida, M; Fakra, E; Azorin, J-M

2016-12-01

The first objective of this article is to summarize the history of electroconvulsive therapy (ECT) in psychiatry in order to highlight the transition from clinical level of evidence based on phenomenological descriptions to controlled trial establishing causal relationship. The second objective is to apply the criteria of causation for ECT, to focus on the dose-effect relationship criteria, and thus to analyze the conditions of application of these criteria for ECT. A literature review exploring the use of electricity, ECT and electroencephalography (EEG) in psychiatry was conducted. The publications were identified from the Pubmed and GoogleScholar electronic databases. The scientific literature search of international articles was performed in July 2016. In 1784, a Royal commission established in France by King Louis XVI tested Mesmer's claims concerning animal magnetism. By doing that, the commission, including such prominent scientists as the chemist Anton Lavoisier and the scientist and researcher on electricity and therapeutics Benjamin Franklin, played a central role in establishing the criteria needed to assess the level of evidence of electrical therapeutics in psychiatry. Surprisingly, it is possible to identify the classical Bradford Hill criteria of causation in the report of the commission, except the dose-effect relationship criteria. Since then, it has been conducted blinded randomized controlled trials that confirmed the effectiveness of ECT against ECT placebos for the treatment of psychiatric disorders. At present, the dose-effect relationship criteria can be analyzed through an EEG quality assessment of ECT-induced seizures. EEG quality assessment includes several indices: TSLOW (time to onset of seizure activity ≤5Hz, seconds), peak mid-ictal amplitude (mm), regularity (intensity or morphology of the seizure (0-6)), stereotypy (global seizure patterning, 0-3) and post-ictal suppression (0-3). A manual rating sheet is needed to score theses

The missing graphical user interface for genomics.

PubMed

Schatz, Michael C

2010-01-01

The Galaxy package empowers regular users to perform rich DNA sequence analysis through a much-needed and user-friendly graphical web interface. See research article http://genomebiology.com/2010/11/8/R86 RESEARCH HIGHLIGHT: With the advent of affordable and high-throughput DNA sequencing, sequencing is becoming an essential component in nearly every genetics lab. These data are being generated to probe sequence variations, to understand transcribed, regulated or methylated DNA elements, and to explore a host of other biological features across the tree of life and across a range of environments and conditions. Given this deluge of data, novices and experts alike are facing the daunting challenge of trying to analyze the raw sequence data computationally. With so many tools available and so many assays to analyze, how can one be expected to stay current with the state of the art? How can one be expected to learn to use each tool and construct robust end-to-end analysis pipelines, all while ensuring that input formats, command-line options, sequence databases and program libraries are set correctly? Finally, once the analysis is complete, how does one ensure the results are reproducible and transparent for others to scrutinize and study?In an article published in Genome Biology, Jeremy Goecks, Anton Nekrutenko, James Taylor and the rest of the Galaxy Team (Goecks et al. 1) make a great advance towards resolving these critical questions with the latest update to their Galaxy Project. The ambitious goal of Galaxy is to empower regular users to carry out their own computational analysis without having to be an expert in computational biology or computer science. Galaxy adds a desperately needed graphical user interface to genomics research, making data analysis universally accessible in a web browser, and freeing users from the minutiae of archaic command-line parameters, data formats and scripting languages. Data inputs and computational steps are selected from

Giovanni Verga (1879-1923), author of a pioneering treatise on pituitary surgery: the foundations of this new field in Europe in the early 1900s.

PubMed

Pascual, José M; Mongardi, Lorenzo; Prieto, Ruth; Castro-Dufourny, Inés; Rosdolsky, María; Strauss, Sewan; Carrasco, Rodrigo; Winter, Eduard; Mazzarello, Paolo

2017-10-01

The field of pituitary surgery was born in the first decade of the twentieth century in Europe, and it evolved rapidly with the development of numerous innovative surgical techniques by some of the founding fathers of neurosurgery. This study investigates the pioneering Italian treatise on pituitary surgery, La Patologia Chirurgica dell'Ipofisi (Surgical Pathology of the Hypophysis), published in 1911 by Giovanni Verga (1879-1923), a surgeon from Pavía and one of Golgi's disciples. This little-known monograph compiles the earliest experience on pituitary surgery through the analysis of the first 50 procedures performed between 1903 and 1911. We conducted a biographical survey of Giovanni Verga and the motivations for his work on pituitary surgery. In addition, a systematic analysis of all original reports and historical documents about these pituitary procedures referenced in Verga's treatise was carried out. Verga's treatise provides a summary of the techniques employed and surgical outcomes for the first 50 attempted procedures of pituitary tumor removal. This monograph is the only scientific source that includes a complete account of the series of 10 pituitary tumors operated on by Sir Victor Horsley in the 1900s. Three major types of surgery were employed: (i) palliative procedures of craniectomy (n = 6); (ii) transcranial approaches to the pituitary gland, either subfrontal or subtemporal (n = 13); and (iii) transphenoidal routes to expose the sella turcica, either using an upper transnasal-transethmoidal approach (n = 19) or a lower sublabial/endonasal-transeptal one (n = 12). An operative mortality rate of 36% (n = 17) was observed in these early series. The pathological nature of the tumors operated on was available in 42 cases. There were 28 adenomas and 15 craniopharyngiomas. Sir Victor Horsley (1857-1916) and the Viennese surgeons Anton von Eiselsberg (1860-1939) and Oskar Hirsch (1877-1965) were the leading European figures in the development

The OD/OH Isotope Ratio in Comets 8P/Tuttle and C/2012 F6 (Lemmon)

NASA Astrophysics Data System (ADS)

Rousselot, Philippe; Jehin, Emmanuel; Hutsemekers, Damien; Manfroid, Jean; Decock, Alice; Bockelee-Morvan, Dominique

2016-10-01

The determination of isotopic ratios in solar system objects is an important source of information about their origin, especially for comets. Among these ratios the D/H is of particular importance because of its sensitivity to fractionation processes and physical environment, and the abundance of hydrogen in the solar system. The main molecule used to derive this ratio in comets is water. So far, apart water, only HCN has permitted to derive D/H ratio and not only upper limits.Most of the existing determinations of D/H in water molecules have been obtained by spectroscopic observations of water lines in the sub-mm or near infrared range [1,2]. So far only one measurement has been based on OD/OH emission lines radicals in the near-UV [3] and another one on the Lyman-alpha D emission [4]. In situ measurements have also been obtained in comets 1P/Halley and 67P/Churyumov-Gerasimenko using mass spectrometer [5,6,7,8].In this work we have used the OH and OD ultraviolet bands at 310 nm observed with the ESO 8-m Very Large Telescope feeding the Ultraviolet-Visual Echelle Spectrograph (UVES) for measuring the D/H ratio in comets 8P/Tuttle and C/2012 F6 (Lemmon). The OH and OD being the photodissociation products of H2O and HDO such observations allow to derive D/H ratio for water molecules. This work constitutes an independant determination of the D/H ratios already published for these comets and based on observations performed in the sub-mm and near infrared range of H2O and HDO lines. We present our modeling, data analysis and numerical values obtained for this ratio.[1] D. Bockelée-Morvan et al., 2015, SSR 197, 47-83 [2] N. Biver et al., 2016, A&A 589, id A78, 11p [3] D. Hutsemékers et al., 2008, A&A 490, L31 [4] H.A. Weaver et al., 2008, LPI Contributions 1405, 8216 [5] H. Balsiger, K. Altwegg, J. Geiss, 1995, JGR 100, 5827 [6] P. Eberhardt et al., 1995, A&A 302, 301 [7] R.H. Brown et al., 2012, PSS 60, 166 [8] K. Alwegg et al., 2015, Science 347, article id. 1261952

Using intra annual density fluctuations and d13C to assess the impact of summer drought on Mediterranean ecosystem

NASA Astrophysics Data System (ADS)

Battipaglia, G.; Brand, W. A.; Linke, P.; Schaefer, I.; Noetzli, M.; Cherubini, P.

2009-04-01

Tree- ring growth and wood density have been used extensively as indicators of climate change, and tree-ring has been commonly applied as a proxy estimate for seasonal integration of temperatures and precipitation with annual resolution (Hughes 2002). While these relationships have been well established in temperate ecosystems (Fritts, 1976; Schweingruber, 1988, Briffa et al., 1998, 2004), in Mediterranean region dendrochronological studies are still scarce (Cherubini et al, 2003). In Mediterranean environment, trees may form intra-annual density fluctuations, also called "false rings" or "double rings" (Tingley 1937; Schulman 1938). They are usually induced by sudden drought events, occurring during the vegetative period, and, allowing intra-annual resolution, they may provide detailed information at a seasonal level, as well as species-specific sensitivity to drought. We investigated the variability of tree- ring width and carbon stable isotopes of a Mediterranean species, Arbutus unedo L., sampled on Elba island, (Tuscany, Italy). The samples were taken at two different sites, one characterized by wet and one by dry conditions. d13C was measured using Laser- Ablation- Combustion -GC-IRMS. Here, we present first results showing the impact of drought on tree growth and on false ring formation at the different sites and we underline the importance of using Laser Ablation to infer drought impact at the intra -annual level. Briffa KR, Schweingruber FH, Jones PD, Osborn TJ, Harris IC, Shiyatov SG, Vaganov EA, Grudd H (1998) Trees tell of past climates: but are they speaking less clearly today? Phil Transact Royal Soc London 353:65-73 Briffa KR, Osborn TJ, Schweingruber FH (2004) Large-scale temperature inferences from tree rings: a review. Glob Panet Change 40:11-26 Cherubini, P., B.L. Gartner, R. Tognetti, O.U. Bräker, W. Schoch & J.L. Innes. 2003. Identification, measurement and interpretation of tree rings in woody species from Mediterranean climates. Biol. Rev

A foundation monograph of Convolvulus L. (Convolvulaceae).

PubMed

Wood, John R I; Williams, Bethany R M; Mitchell, Thomas C; Carine, Mark A; Harris, David J; Scotland, Robert W

2015-01-01

A global revision of Convolvulus L. is presented, Calystegia R.Br. being excluded on pragmatic grounds. One hundred and ninety species are recognised with the greatest diversity in the Irano-Turanian region. All recognised species are described and the majority are illustrated. Distribution details, keys to species identification and taxonomic notes are provided. Four new species, Convolvulusaustroafricanus J.R.I.Wood & R.W.Scotland, sp. nov., Convolvulusiranicus J.R.I.Wood & R.W.Scotland, sp. nov., Convolvuluspeninsularis J.R.I.Wood & R.W.Scotland, sp. nov. and Convolvulusxanthopotamicus J.R.I.Wood & R.W.Scotland, sp. nov., one new subspecies Convolvuluschinensissubsp.triangularis J.R.I.Wood & R.W.Scotland, subsp. nov., and two new varieties Convolvulusequitansvar.lindheimeri J.R.I.Wood & R.W.Scotland, var. nov., Convolvulusglomeratusvar.sachalitarum J.R.I.Wood & R.W.Scotland, var. nov. are described. Convolvulusincisodentatus J.R.I.Wood & R.W.Scotland, nom. nov., is provided as a replacement name for the illegitimate Convolvulusincisus Choisy. Several species treated as synonyms of other species in recent publications are reinstated including Convolvuluschinensis Ker-Gawl., Convolvulusspinifer M.Popov., Convolvulusrandii Rendle and Convolvulusaschersonii Engl. Ten taxa are given new status and recognised at new ranks: Convolvulusnamaquensis (Schltr. ex. A.Meeuse) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulushermanniaesubsp.erosus (Desr.) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvuluscrenatifoliussubsp.montevidensis (Spreng.) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulusfruticulosussubsp.glandulosus (Webb) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvuluscapituliferussubsp.foliaceus (Verdc.) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulushystrixsubsp.ruspolii (Dammer ex Hallier f.) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulushystrixsubsp.inermis (Chiov.) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulusrottlerianussubsp.stocksii (Boiss.) J

The NA62 trigger system

NASA Astrophysics Data System (ADS)

Krivda, M.; NA62 Collaboration

2013-08-01

The main aim of the NA62 experiment (NA62 Technical Design Report, [1]) is to study ultra-rare Kaon decays. In order to select rare events over the overwhelming background, central systems with high-performance, high bandwidth, flexibility and configurability are necessary, that minimize dead time while maximizing data collection reliability. The NA62 experiment consists of 12 sub-detector systems and several trigger and control systems, for a total channel count of less than 100,000. The GigaTracKer (GTK) has the largest number of channels (54,000), and the Liquid Krypton (LKr) calorimeter shares with it the largest raw data rate (19 GB/s). The NA62 trigger system works with 3 trigger levels. The first trigger level is based on a hardware central trigger unit, so-called L0 Trigger Processor (L0TP), and Local Trigger Units (LTU), which are all located in the experimental cavern. Other two trigger levels are based on software, and done with a computer farm located on surface. The L0TP receives information from triggering sub-detectors asynchronously via Ethernet; it processes the information, and then transmits a final trigger decision synchronously to each sub-detector through the Trigger and Timing Control (TTC) system. The interface between L0TP and the TTC system, which is used for trigger and clock distribution, is provided by the Local Trigger Unit board (LTU). The LTU can work in two modes: global and stand-alone. In the global mode, the LTU provides an interface between L0TP and TTC system. In the stand-alone mode, the LTU can fully emulate L0TP and so provides an independent way for each sub-detector for testing or calibration purposes. In addition to the emulation functionality, a further functionality is implemented that allows to synchronize the clock of the LTU with the L0TP and the TTC system. For testing and debugging purposes, a Snap Shot Memory (SSM) interface is implemented, that can work

Perspective View with Color-Coded Shaded Relief, Central Panama

NASA Technical Reports Server (NTRS)

2002-01-01

This perspective view shows central Panama, with the remnants of the extinct volcano El Valle in the foreground and the Caribbean Sea in the distance. El Valle underwent an explosive eruption about 3 million years ago, forming a crater 5 kilometers (3.1 miles) across, one of the largest in the Americas. The crater subsequently filled with water forming a huge lake, but about 12,000 years ago a breach at the present site of the waterfall Choro de las Mozas caused it to drain, forming the present valley. Within the crater is the town of El Valle de Anton, whose 600-meter (1,968-foot) elevation and resulting cooler climate make it a popular tourist and vacation site.

The lake in the distance is Lake Gatun, at the west end of the Panama Canal. The canal itself extends to the southwest (to the right in this northeast facing view) but is hidden by the intervening terrain.

This shaded relief perspective view was generated using topographic data from the Shuttle Radar Topography Mission (SRTM). A computer-generated artificial light source illuminates the elevation data to produce a pattern of light and shadows. Slopes facing the light appear bright, while those facing away are shaded. On flatter surfaces, the pattern of light and shadows can reveal subtle features in the terrain. Colors show the elevation as measured by SRTM, and range from green at the lowest elevations to white at the highest elevations.

SRTM, launched on February 11, 2000, uses the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. The mission is designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, an additional C-band imaging antenna and improved tracking and navigation devices. The mission is a cooperative project between NASA, the National Imagery and Mapping Agency (NIMA) and the

[Mental disease in two classical music composers].

PubMed

Rempelakos, L; Poulakou-Rebelakou, E; Ploumpidis, D

2012-01-01

A study οn two neglected classical music composers suffering a not syphilitic mental disease, is attempted here, syphilis of the central nervous system being frequent in that time. A brief overview on the psychiatric ailments of many great composers reveals suicide attempts and more or less severe depression following external events. The issue of a possible relationship between mental disease and (musical) creativity can be discussed, as mood swings and a certain tendency to melancholia are frequent features of a talented brain (a fact that can also be detected in their works). The first case presented here is Hans Rott from Austria, the beloved student of Anton Bruckner, who was considered to be at least equal to his famous classmate Gustav Mahler. The great expectations of his teacher and his friends suddenly came to an end, when he suffered a crisis of schizophrenia and was hospitalized in an insane asylum in Lower Austria. The tragic psychiatric adventure of the young musician lasted almost four years. He was diagnosed as a case of "hallucinatory insanity" and "persecution mania" by the medical staff, before dying of tuberculosis, aged only 26, and having completed only one symphony and several smaller works. His name came again on surface only a century after his death, when in 1989 his Symphony in E Major was discovered and premiered with great success, permitting to its creator a posthumous recognition, among Bruckner and Mahler. The second case of mental illness is that of the Armenian Komitas Vardapet. He was an orphan who grew up in theological schools and became a monk and later a priest, though he spent some years in Berlin in order to develop his musical skills. He is considered to be an authority of Armenian ecclesiastic music, introducing polyphony in the Armenian Church's music and collecting numerous traditional songs from all parts of Armenia. In 1915, during the Armenian genocide he was deported, tortured but finally saved, due to interventions

Shear thinning behaviors in magmas

NASA Astrophysics Data System (ADS)

Vetere, F. P.; Cassetta, M.; Perugini, D.

2017-12-01

Studies on magma rheology are of fundamental importance to understanding magmatic processes from depth to surface. Since viscosity is one of the most important parameter controlling eruption mechanisms, as well as lava flow emplacement, a comprehensive knowledge on the evolution of magma viscosities during crystallization is required. We present new viscosity data on partly crystalized basalt, andesite and analogue lavas comparable to those erupted on Mercury's northern volcanic plains. High-temperature viscosity measurements were performed using a rotational Anton Paar RheolabQC viscometer head at the PVRG labs, in Perugia (Italy) (http://pvrg.unipg.it). The relative proportion of phases in each experimental run were determined by image analysis on BS-SEM images at different magnifications; phases are glasses, clinopyroxene, spinel, plagioclase for the basalt, plagioclase and spinel for the andesite and pure enstatite and clinopyroxenes, for the analogue Mercury's composition. Glass and crystalline fractions determined by image analysis well correlate with compositions of residual melts. In order to constrain the viscosity (η) variations as a function of crystallinity, shear rate (γ) was varied from 0.1 to 5 s-1. Viscosity vs. time at constant temperature shows a typical S-shape curve. In particular, for basaltic composition η vary from 3.1-3.8 Pa s [log η] at 1493 K and crystallinity of 19 area % as γ vary from 1.0 to 0.1 s-1; the andesite viscosity evolution is 3.2 and 3.7 Pa s [log η] as γ varies from 1 to 0.1 at 1493 K and crystal content of 17 area %; finally, Mercury's analogue composition was investigated at different temperature ranging from 1533 to 1502 K (Vetere et al., 2017). Results, for γ = 0.1, 1.0 and 5.0 s-1, show viscosity variation between 2.7-4.0, 2.5-3.4 and 2.0-3.0 [log η inPa s] respectively while crystallinity vary from 9 to 27 (area %). As viscosity decreases as shear rate increases, these data points to a shear thinning behaviour

Possible changes in ground-water flow to the Pecos River caused by Santa Rosa Lake, Guadalupe County, New Mexico

USGS Publications Warehouse

Risser, D.W.

1987-01-01

In 1980 Santa Rosa Dam began impounding water on the Pecos River about 7 miles north of Santa Rosa, New Mexico, to provide flood control, sediment control, and storage for irrigation. Santa Rosa Lake has caused changes in the groundwater flow system, which may cause changes in the streamflow of the Pecos River that cannot be detected at the present streamflow gaging stations. Data collected at these stations are used to measure the amount of water available for downstream users. A three-dimensional groundwater flow model for a 950 sq mi area between Anton Chico and Puerto de Luna was used to simulate the effects of Santa Rosa Lake on groundwater flow to a gaining reach of the Pecos River for lake levels of 4,675, 4,715, 4,725, 4,750, 4,776, and 4,797 feet above sea level and durations of impoundment of 30, 90, 182, and 365 days for all levels except 4 ,797 feet. These simulations indicated that streamflow in the Pecos River could increase by as much as 2 cu ft/sec between the dam and Puerto de Luna if the lake level were maintained at 4 ,797 feet for 90 days or 4,776 feet for 1 year. About 90% of this increased streamflow would occur < 0.5 mi downstream from the dam, some of which would be measured at the streamflow gaging station located 0.2 mile downstream from the dam. Simulations also indicated that the lake will affect groundwater flow such that inflow to the study area may be decreased by as much as 1.9 cu ft/sec. This water may leave the Pecos River drainage basin or be diverted back to the Pecos River downstream from the gaging station near Puerto de Luna. In either case, this quantity represents a net loss of water upstream from Puerto de Luna. Most simulations indicated that the decrease in groundwater flow into the study area would be of about the same quantity as the simulated increase in streamflow downstream from the dam. Therefore, the net effect of the lake on the flow of the Pecos River in the study area appears to be negligible. Model simulations

Müller cell gliotic response in the retina of the newts exposed to real and simulated microgravity

NASA Astrophysics Data System (ADS)

Grigoryan, Eleonora N.; Poplinskaya, Valentina; Domaratskaya; Aleinikova, Karina; Novikova, Julia; Anton, Hermann J.; Almeida, Eduardo

The effects of real and simulated microgravity on the eye tissue regeneration of newts (Pl. waltli) after lens and/or retina removal were investigated. Changes in Müller glial cells in the retina of eyes regenerating after lens extirpation were detected in newts exposed to clinostat-ing. The cells were hypertrophied, and their processes thickened. Such changes were viewed as specific of reactive gliosis [1]. Later experiments onboard the Russian biosatellite Bion-11 showed similar changes in the retinas of newts regenerating after a two-week spaceflight. In the Bion-11 animals, GFAP, the major structural protein of macroglial cells was found to be up-regulated [2]. In more recent experiments onboard Foton-2 (2005) and Foton-M3 (2007), GFAP expression in retinas of space-flown, ground control (kept at 1 g), and basal control (sacrificed on launch day) newts was quantified, using microscopy, immunohistochemistry, and digital image analysis. It was found that Müller cell processes of non-operated animals dis-u played low GFAP immunolabeling. A low level of immunoreactivity was also observed in basal controls. In contrast, retinas of space-flown animals showed greater GFAP immunoreactivity associated with both an increased cell number and a higher density of intermediate filaments [3]. This, in turn, was accompanied by up-regulation of stress protein (HSP90) and growth factor (FGF2) expressions. It can be postulated that such a response of Müller cells was to mitigate the retinal stress in newts exposed to microgravity. Although the exact mechanisms remain unknown, it can be hypothesized that GFAP up-regulation is mediated by HSPs and growth factors, particularly by FGF2. Taken together, these data suggest that the retinal population of macroglial cells is sensitive to gravity changes and that in space it can react by enhancing its neuroprotective function. [1] Grigoryan E.N., Anton H.J., Mitashov V.I. Adv. Space Res. 1998. V. 22. N.2. P. 293-301. [2] Grigoryan E

Kinematics of an oblique deformation front using paleomagnetic data; the Altomira-Loranca structures (Iberian Chain, Central Spain)

NASA Astrophysics Data System (ADS)

Valcarcel, M.

2013-05-01

Manoel Valcárcel1, 5, Ruth Soto2, Elisabet Beamud3, Belén Oliva-Urcia4 and Josep Anton Muñoz5 1 IGME, Departamento de Investigación y Prospección Geocientífica. C/ La Calera, 1, 28760 Tres Cantos; m.valcarcel@igme.es 2 IGME, Unidad de Zaragoza, C/ Manuel Lasala 44, 9 B, 50006 Zaragoza, Spain 3 Lab. Paleomagnetisme (CCiT UB-CSIC). ICT "Jaume Almera", Solé i Sabarís, s/n, 08028 Barcelona, Spain. 4 IPE-CSIC, Avda. Montañana 1005, 50059 Zaragoza, Spain 5 Grup Geodinàmica i Anàlisi de Conques, Universitat de Barcelona, Zona Universitària Pedralbes, 08028 Barcelona, Spain The Altomira and Loranca structures consist of a fold-and-thrust system detached on Triassic evaporites. They are oriented N-S to NNE-SSW and NNW-SSE at its northern and southern end, respectively, forming a subtle arc, oblique with respect to the general NW-SE trend of the Iberian Chain. The aim of this work is to characterize with paleomagnetic data the kinematic evolution of the the Altomira Range, located at the southwestern deformation front of the Iberian Chain, and of the structures within its associated piggy-back basin, the Loranca basin. This approach will also give clues regarding the primary and/or secondary origin of these structures to better characterize them in further studies (3D reconstruction and restoration, fault pattern). A total of 180 samples were obtained from 19 sites in Eocene, Oligocene and Miocene rocks (including clays, fine sandstones and limestones). They were analyzed by means of stepwise thermal demagnetization and subsequent measurement of the natural remanent magnetization (NRM). Although fold tests are not statistically significant, a primary origin of the magnetization is deduced by samples showing either normal or reverse polarity after bedding correction of the calculated characteristic components. Declinations of the site mean directions appear scattered after bedding correction suggesting differential vertical-axis rotations. Sites located at the

A foundation monograph of Convolvulus L. (Convolvulaceae)

PubMed Central

Wood, John R.I.; Williams, Bethany R.M.; Mitchell, Thomas C.; Carine, Mark A.; Harris, David J.; Scotland, Robert W.

2015-01-01

Abstract A global revision of Convolvulus L. is presented, Calystegia R.Br. being excluded on pragmatic grounds. One hundred and ninety species are recognised with the greatest diversity in the Irano-Turanian region. All recognised species are described and the majority are illustrated. Distribution details, keys to species identification and taxonomic notes are provided. Four new species, Convolvulus austroafricanus J.R.I.Wood & R.W.Scotland, sp. nov., Convolvulus iranicus J.R.I.Wood & R.W.Scotland, sp. nov., Convolvulus peninsularis J.R.I.Wood & R.W.Scotland, sp. nov. and Convolvulus xanthopotamicus J.R.I.Wood & R.W.Scotland, sp. nov., one new subspecies Convolvulus chinensis subsp. triangularis J.R.I.Wood & R.W.Scotland, subsp. nov., and two new varieties Convolvulus equitans var. lindheimeri J.R.I.Wood & R.W.Scotland, var. nov., Convolvulus glomeratus var. sachalitarum J.R.I.Wood & R.W.Scotland, var. nov. are described. Convolvulus incisodentatus J.R.I.Wood & R.W.Scotland, nom. nov., is provided as a replacement name for the illegitimate Convolvulus incisus Choisy. Several species treated as synonyms of other species in recent publications are reinstated including Convolvulus chinensis Ker-Gawl., Convolvulus spinifer M.Popov., Convolvulus randii Rendle and Convolvulus aschersonii Engl. Ten taxa are given new status and recognised at new ranks: Convolvulus namaquensis (Schltr. ex. A.Meeuse) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulus hermanniae subsp. erosus (Desr.) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulus crenatifolius subsp. montevidensis (Spreng.) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulus fruticulosus subsp. glandulosus (Webb) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulus capituliferus subsp. foliaceus (Verdc.) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulus hystrix subsp. ruspolii (Dammer ex Hallier f.) J.R.I.Wood & R.W.Scotland, stat. nov., Convolvulus hystrix subsp. inermis (Chiov.) J.R.I.Wood & R.W.Scotland, stat. nov

Viscosity of carbonate-rich melts under different oxygen fugacity conditions

NASA Astrophysics Data System (ADS)

Di Genova, Danilo; Hess, Kai-Uwe; Cimarelli, Corrado; Dingwell, Donald B.

2015-04-01

Viscosity is a fundamental property of many materials and its changes affects the fluid dynamics of natural system as well as industrial processes. The mobility of carbonatitic melts, which are carbonate-rich and very fluid melts, has attracted renewed interest in both earth science and industry. In fact, these melts are considered the main transport agent of carbon from the mantle to the crust and may be intimately linked to the generation of kimberlites. At the same time lithium, potassium and sodium carbonate are used as electrolytes in molten carbonate fuel cells which operate at high temperatures (~650° C) for the production of electricity without CO2 emissions. Accurate measurement of the transport property (i.e. viscosity) of carbonatitic melts is a priority in order to understand the carbonatite mobility and reaction rates. Additionally, obtaining accurate viscosity measurements of such low viscosity melts is however an experimental challenge due to volatility, very low torques and chemical melt instability in the viscometer. To overcome these limitations we have customized a Modular Compact Rheometer (MCR 502 from Anton Paar) ad hoc equipped with 2 narrow gap concentric-cylinder geometries of steel and Pt-Au. The rheometer is characterized by an air-bearing-supported synchronous motor with torque ranging between 0.01 μNm and 230 mNm (resolution of 0.1 nNm), achieving very low viscosity measurements in the order of mPa s, temperatures up to 1000° C and shear rates ranging between 1 and 100 sec-1. These experimental conditions well match the temperature-viscosity-shear rate window relevant for carbonate melts. Here we present the calibration of the rheometer and the results of a rheological characterization study on a series of very low viscous synthetic and natural carbonatitic melts at different oxygen fugacity (air and CO2 saturated atmosphere). Viscosity measurements on carbonate melts have been performed in the temperature range between ~650 and 1000

The update of resist outgas testing for metal containing resists at EIDEC

NASA Astrophysics Data System (ADS)

Shiobara, Eishi; Mikami, Shinji

2017-10-01

work was supported by Ministry of Economy, Trade and Industry (METI) and New Energy and Industrial Technology Development Organization (NEDO). [1] Eishi Shiobara, Shinji Mikami, Satoshi Tanaka, International Symposium on EUV Lithography, Hiroshima, Japan, P-RE-01, (2016). [2] Mark van de Kerkhof, Hans Jasper, Leon Levasier, Rudy Peeters, Roderik van Es, Jan-Willem Bosker, Alexander Zdravkov, Egbert Lenderink, Fabrizio Evangelista, Par Broman, Bartosz Bilski, Thorsten Last, Proc. of SPIE Vol. 10143, 101430D (2017). [3] Oktay Yildirim, Elizabeth Buitrago, Rik Hoefnagels, Marieke Meeuwissen, Sander Wuister, Gijsbert Rispens, Anton van Oosten, Paul Derks, Jo Finders, Michaela Vockenhuber, Yasin Ekinci, Proc. of SPIE Vol. 10143, 101430Q (2017).

Music and the Nature: Input of the Czech Composers

NASA Astrophysics Data System (ADS)

Nemec, Vaclav; Nemcova, Lidmila

2014-05-01

Extraordinary occasions for art of any kind - music, creative graphic and plastic arts, literature (classic, modern incl. science fiction), theatre, cinema, etc. - exist to harmonise individual personal interests with those of the humanity well-being and of the Nature and also to cultivate individual spirituality and the appropriate values. Arts can be applied as irreplaceable means for making any human being better, for improving his sense for solidarity and for increasing his ethical sensibility. An interest for the art should be cultivated already since the childhood. - How much of inspiration for numerous composers all over the world has been given by the Nature, how much of inspiration for people who by listening to such a music are increasing nobility of their behaviour as well as their friendly approach to the Nature. - Many classical music works have been written with a strong inspiration by the Nature itself from the past until today. The actual Year of the Czech Music gives the possibility to present the most famous Czech composers inspired by the Nature (selected examples only): Bedřich Smetana (1824 - 1884): At the sea shore - a concert etude for piano inspired by his stay in Göteborg (Sweden); Vltava (Moldau) - a symphonic poem from the cycle "My country" inspired by the river crossing Bohemia from the South to Prague; From the Bohemian woods and meadows - another symphonic poem from the same cycle. Antonín Dvořák (1841 - 1904): V přírodě (In the Nature) - a work for orchestra Leoš Janáček (1854 - 1928): Příhody li\\vsky Bystrou\\vsky (The Cunning Little Vixen) - an opera situated mostly in a forest. Josef Bohuslav Foerster (1859-1951): Velké širé rodné lány (Big large native fields) - a choir for men singers inspired by the nature in the region where the composer as a boy from Prague was visiting his grand-father. Vítězslav Novák (1870 - 1949): In Tatra mountains - a symphonic poem expressing the author's passion for the famous

Maribor General Hospital from its foundation until World War II.

PubMed

Pivec, Gregor

2006-01-01

The author describes the history of Maribor General Hospital from its foundation in 1799 until the beginning of World War II. In 1799 the magistrate of the town of Maribor issued a memorandum regarding the establishment of a town hospital in the renovated building of the town hospice, providing space for 24 patients. The work of the hospital was carried out in the former hospice building until 1855. In the period between its establishment and eventual relocation 26 beds were added. The last two decades of the hospital's operation at the original location were marked by the assiduous work of the town's physicist, Dr. Anton Kuker. In the first half of the 19th century, the population of Maribor grew rapidly as a consequence of the construction of the Southern Railway. The town authorities therefore purchased the Prosenjak family villa in the Magdalena suburbs and relocated the hospital to it in 1855, providing 28 rooms for 110 patients. For a whole century, the care of patients was taken over by the Daughters of Charity of Saint Vincent de Paul. The hospital was soon admitting over 1000 patients a year, the most common complaints being pulmonary catarrh, gastritis and fever. In 1872, when the Master of Surgery Feliks Ferk joined the hospital, the internal "medical" and the "external" surgical departments were formed. Although medical studies were not easily accessible, there were a number of Slovene physicians working in the hospital and the town in that period. In the last decades of the 19th century, the hospital was often renovated and enlarged. The infrastructure (telephone, water supply system, heating, lighting) had also been modernized before World War I. In 1914, the first X-ray apparatus was purchased. Between the wars, the hospital's development was boosted by recruitment of the Slovene physicians Ivan Matko, Mirko Cernic, Janko Dernovsek and Hugon Robic. The initial external and medical departments split into several departments: internal medicine, surgery

NVP melt/magma viscosity: insight on Mercury lava flows

NASA Astrophysics Data System (ADS)

Rossi, Stefano; Morgavi, Daniele; Namur, Olivier; Vetere, Francesco; Perugini, Diego; Mancinelli, Paolo; Pauselli, Cristina

2016-04-01

After more than four years of orbiting Mercury, NASA's MESSENGER spacecraft came to an end in late April 2015. MESSENGER has provided many new and surprising results. This session will again highlight the latest results on Mercury based on MESSENGER observations or updated modelling. The session will further address instrument calibration and science performance both retrospective on MESSENGER and on the ESA/JAXA BepiColombo mission. Papers covering additional themes related to Mercury are also welcomed. Please be aware that this session will be held as a PICO session. This will allow an intensive exchange of expertise and experience between the individual instruments and mission. NVP melt/magma viscosity: insight on Mercury lava flows S. Rossi1, D. Morgavi1, O. Namur2, D. Perugini1, F.Vetere1, P. Mancinelli1 and C. Pauselli1 1 Dipartimento di Fisica e Geologia, Università di Perugia, piazza Università 1, 06123 Perugia, Italy 2 Uni Hannover Institut für Mineralogie, Leibniz Universität Hannover, Callinstraβe 3, 30167 Hannover, Germany In this contribution we report new measurements of viscosity of synthetic komatitic melts, used the behaviour of silicate melts erupted at the surface of Mercury. Composition of Mercurian surface magmas was calculated using the most recent maps produced from MESSENGER XRS data (Weider et al., 2015). We focused on the northern hemisphere (Northern Volcanic Province, NVP, the largest lava flow on Mercury and possibly in the Solar System) for which the spatial resolution of MESSENGER measurements is high and individual maps of Mg/Si, Ca/Si, Al/Si and S/Si were combined. The experimental starting material contains high Na2O content (≈7 wt.%) that strongly influences viscosity. High temperature viscosity measurements were carried out at 1 atm using a concentric cylinder apparatus equipped with an Anton Paar RheolabQC viscometer head at the Department of Physics and Geology (PVRG_lab) at the University of Perugia (Perugia, Italy

Meso-Scale Modelling of Deformation, Damage and Failure in Dual Phase Steels

NASA Astrophysics Data System (ADS)

Sari Sarraf, Iman

Advanced high strength steels (AHSS), such as dual phase (DP) and transformation induced plasticity (TRIP) steels, offer high ductility, formability, and strength, as well as high strength-to-weight ratio and improved crash resistance. Dual phase steels belong to a family of high strength grades which consist of martensite, responsible for strengthening, distributed in a ductile ferrite matrix which accommodates the deformation throughout the forming process. It has been shown that the predominant damage mechanism and failure in DP steels depends on the ferrite and martensite grain sizes and their morphology, and can range from a mixture of brittle and ductile rupture to completely ductile rupture in a quasi-static uniaxial tension test. In this study, a hybrid finite element cellular automata model, initially proposed by Anton Shterenlikht (2003), was developed to evaluate the forming behaviour and predict the onset of instability and damage evolution in a dual phase steel. In this model, the finite element constitutive model is used to represent macro-level strain gradients and a damage variable, and two different cell arrays are designed to represent the ductile and brittle fracture modes in meso-scale. In the FE part of the model, a modified Rousselier ductile damage model is developed to account for nucleation, growth and coalescence of voids. Also, several rate-dependent hardening models were developed and evaluated to describe the work hardening flow curve of DP600. Based on statistical analysis and simulation results, a modified Johnson-Cook (JC) model and a multiplicative combination of the Voce-modified JC functions were found to be the most accurate hardening models. The developed models were then implemented in a user-defined material subroutine (VUMAT) for ABAQUS/Explicit finite element simulation software to simulate uniaxial tension tests at strain rates ranging from 0.001 1/s to 1000 1/s, Marciniak tests, and electrohydraulic free-forming (EHFF

Platelet Rich Plasma and Hyaluronic Acid Blend for the Treatment of Osteoarthritis: Rheological and Biological Evaluation

PubMed Central

Russo, Fabrizio; D’Este, Matteo; Vadalà, Gianluca; Cattani, Caterina; Papalia, Rocco; Alini, Mauro; Denaro, Vincenzo

2016-01-01

Introduction Osteoarthritis (OA) is the most common musculoskeletal disease. Current treatments for OA are mainly symptomatic and inadequate since none results in restoration of fully functional cartilage. Hyaluronic Acid (HA) intra-articular injections are widely accepted for the treatment of pain associated to OA. The goal of HA viscosupplementation is to reduce pain and improve viscoelasticity of synovial fluid. Platelet-rich plasma (PRP) has been also employed to treat OA to possibly induce cartilage regeneration. The combination of HA and PRP could supply many advantages for tissue repair. Indeed, it conjugates HA viscosupplementation with PRP regenerative properties. The aim of this study was to evaluate the rheological and biological properties of different HA compositions in combination with PRP in order to identify (i) the viscoelastic features of the HA-PRP blends, (ii) their biological effect on osteoarthritic chondrocytes and (iii) HA formulations suitable for use in combination with PRP. Materials and Methods HA/PRP blends have been obtained mixing human PRP and three different HA at different concentrations: 1) Sinovial, 0.8% (SN); 2) Sinovial Forte 1.6% (SF); 3) Sinovial HL 3.2% (HL); 4) Hyalubrix 1.5% (HX). Combinations of phosphate buffered saline (PBS) and the four HA types were used as control. Rheological measurements were performed on an Anton PaarMCR-302 rheometer. Amplitude sweep, frequency sweep and rotational measurements were performed and viscoelastic properties were evaluated. The rheological data were validated performing the tests in presence of Bovine Serum Albumin (BSA) up to ultra-physiological concentration (7%). Primary osteoarthritic chondrocytes were cultured in vitro with the HA and PRP blends in the culture medium for one week. Cell viability, proliferation and glycosaminoglycan (GAG) content were assessed. Results PRP addition to HA leads to a decrease of viscoelastic shear moduli and increase of the crossover point, due to a

Crustal Structure in the Southern Rockall Trough from Satellite Gravity Data: Evidence for Sea-floor Spreading

NASA Astrophysics Data System (ADS)

Chappell, A.; Kusznir, N. J.

2005-05-01

The southern Rockall Trough south of 57 N has previously been interpreted as either an intra-continental rift floored with highly extended continental crust, or a failed oceanic rift formed by Cretaceous sea floor spreading. Satellite gravity, bathymetry data and seismic estimates of sediment thickness are used to derive crustal basement thickness for the southern Rockall Trough and adjacent regions using a gravity inversion method incorporating a correction for the large negative thermal gravity component present in oceanic and stretched continental lithosphere. The marine Bouguer anomaly, derived from satellite free air gravity (Sandwell & Smith 1997) and Gebco 2003 bathymetry data, is inverted using the method of Oldenberg (1974), incorporating an iteratively applied thermal anomaly correction, to give Moho depth. For oceanic crust the thermal anomaly correction is calculated using isochron ages (Muller et al. 1997) and for continental crust from the beta stretching factors resulting from gravity derived crustal basement thickness and an assumed rift age. When sediment thickness and volcanic addition are assumed to be zero, the resulting upper bound of crustal thickness from the gravity inversion is as little as 10 km in the southern Rockall Trough. A segmented axial thickening of the crust at the centre of the Rockall Trough is predicted, between the Barra volcanic ridge and the Anton Dohrn seamount and is interpreted as having a volcanic origin. Inclusion of a sediment thickness correction in the gravity inversion further reduces predicted crustal thickness. A pseudo-sediment-thickness map has been constructed from the available wide-angle data and incorporated in the gravity inversion. The addition of up to 5.5 km of sediment in the gravity inversion reduces the upper bound of crustal thickness to less than 3 km in some locations. The segmented axial thickening and thin crust shown by the gravity inversion, the lack of intra-basinal faulting, and the volcanic

The "DREAM" IODP project to drill the Mediterranean Salt Giant on the Balearic Promontory

NASA Astrophysics Data System (ADS)

Lofi, Johanna; Camerlenghi, Angelo; Aloisi, Giovanni; Maillard, Agnès; Garcia-Castellanos, Daniel; Huebscher, Christian; Kuroda, Junichiro

2017-04-01

should allow testing 1) the contradictory emplacement models that explain its genesis and 2) the presence of halophilic micro-organisms it may host/feed. DREAM is a part of a bigger Multi-phase IODP Drilling Project entitled "Uncovering a Salt Giant" (857-MDP, coord. A. Camerlenghi) born out of a series of workshops and international initiatives carried out since 2014. The DREAM pre-proposal P857B has been accepted by the IODP Science Evaluation Panel in January 2016. The full-proposal will be submitted after the acquisition of complementary Site Survey Data in 2017. The DREAM project is performed in close link with various international initiatives including the COST Action CA15103 and ANR Project MEDSALT (Camerlenghi et al., this congress) and the IMMAGE ICDP-IODP amphibious proposal (Flecker et al., this congress). DREAM co-proponents: J. Anton, M.A. Bassetti, D. Birgel, R. Bourillot, A. Caruso, H. Daigle, G. DeLange, F. Dela Pierre, R. Flecker, V. Gaullier, D. Hodell, F. Jimenez-Espejo, W. Krijgsman, L. Lourens, S. Lugli, V. Manzi, T. McGenity, J. McKenzie, P. Meijer, H. Moreno, A. Moscariello, P. Munch, N. Ohkouchi, J. Peckmann, P. Pezard, J. Poort, M. Roveri, F. Sierro, K. Takai, T. Treude.

Optical and Acoustical Techniques for Non-viral Gene Delivery to Mammalian Cells and In-situ Study of Cytoskeletal Mechanics

NASA Astrophysics Data System (ADS)

Ma, Zili

Since the first optical microscope invented by Anton van Leeuwenhoek in 1674, the great development of laser technique and its applications in biophotonics have helped us reveal the mechanisms underlying numerous biological activities gradually. The introduction of fs lasers to the studies of biology has emerged as a fast developing area calling for the efforts and skills both from optics and electric engineering and biology and medicine. Due to the fast update of laser source techniques, there has been an increasing number of commercialized fs lasers available for this growing market of biophotonics. To better utilize the potential offered by fs lasers, we studied the technique of optical gene delivery and tried to narrow the gap between laboratorial research and industrial/clinical applications, in that the strict experimental conditions of specific optical laboratorial studies are generally not appropriate for the practical biological applications. To carry out our experiments, we built a two-stage amplifier fs laser system to generate the desired pulse train. The laser pulse train was coupled into an invert fluorescence microscope for the imaging and manipulation of each cell. To overcome limitations brought by the tight focus of laser beam due to high NA objective, we introduced gold nanorods (GNRs), a metallic nanomaterial, with tunable optical property. With these additional membrane for membrane permeabilization, which could significantly improve the manipulation speed than that based on the tightly focused laser. We used GFP plasmid to demonstrate the applications of this technique in gene delivery, and successfully transfected and GFP-expressed cells were observed one day after the optical transfection. Additionally, as an important trend of biophotonics, the integration of optics with microfluidic chips has become the new frontier of both biology and engineering. Here we firstly demonstrated a technique of gene delivery by an on-chip device generating

Adherence to Web-Based Self-Assessments in Long-Term Direct-to-Patient Research: Two-Year Study of Multiple Sclerosis Patients.

PubMed

Jongen, Peter Joseph; Kremer, Ingrid E H; Hristodorova, Elena; Evers, Silvia M A A; Kool, Anton; van Noort, Esther M; Hiligsmann, Mickaël

2017-07-21

completion adherent for the MSQoL-54 and MA questionnaires, respectively. Whereas 85.5% (142/166) of the patients were interval adherent for the MSIP and MSQoL-54, 25.5% (41/161) were interval adherent for the MA questionnaire, with 73.9% (119/161) exceeding the maximum MA monthly interassessment interval. Completion adherence for the monthly short MA questionnaire was higher in patients with moderately high disability (EDSS 5.0-5.5) than for those with no or minimal disability (EDSS 0-2.5) (OR 5.47, 95% CI 1.08-27.69; P=.040). Completion adherence was also higher in patients with EDSS assessment within 6 months after baseline than in those with later assessment (OR 1.810, 95% CI 0.999-3.280; P=.050). The 2-year completion adherence to Web-based self-assessments did not differ between the low-frequency long questionnaires and a high-frequency short questionnaire, but the interval adherence was substantially higher for the low-frequency long questionnaires. Personal contact with a member of the research team regarding a clinically relevant professional-reported outcome early in the study might positively affect the long-term completion adherence in direct-to-patient studies. ©Peter Joseph Jongen, Ingrid E.H. Kremer, Elena Hristodorova, Silvia M.A.A. Evers, Anton Kool, Esther M van Noort, Mickaël Hiligsmann. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.07.2017.

Visions of Discovery

NASA Astrophysics Data System (ADS)

Chiao, Raymond Y.; Cohen, Marvin L.; Leggett, Anthony J.; Phillips, William D.; Harper, Charles L., Jr.

2010-10-01

physics? Steven Chu; 20. Quantum information J. Ignacio Cirac; 21. Emergence in condensed matter physics Marvin L. Cohen; 22. Achieving the highest spectral resolution over the widest spectral bandwidth: precision measurement meets ultrafast science Jun Ye; 23. Wireless non-radiative energy transfer Marin Soljačić; Part V. Consciousness and Free Will: 24. The big picture: exploring questions on the boundaries of science - consciousness and free will George F. R. Ellis; 25. Quantum entanglement: from fundamental questions to quantum communication and quantum computation and back Anton Zeilinger; 26. Consciousness, body, and brain: the matter of the mind Gerald M. Edelman; 27. The relation between quantum mechanics and higher brain functions: lessons from quantum computation and neurobiology Christof Koch and Klaus Hepp; 28. Free will and the causal closure of physics Robert C. Bishop; 29. Natural laws and the closure of physics Nancy L. Cartwright; 30. Anti-Cartesianism and downward causation: reshaping the free-will debate Nancey Murphy; 31. Can we understand free will? Charles H. Townes; Part VI. Reflections on the Big Questions: Mind, Matter. Mathematics, and Ultimate Reality: 32. The big picture: exploring questions on the boundaries of science - mind, matter, mathematics George F. R. Ellis; 33. The mathematical universe Max Tegmark; 34. Where do the laws of physics come from? Paul C. W. Davies; 35. Science, energy, ethics, and civilization Vaclav Smil; 36. Life of science, life of faith William T. Newsome; 37. The science of light and the light of science: an appreciative theological reflection on the life and work of Charles Hard Townes Robert J. Russell; 38. Two quibbles about 'ultimate' Gerald Gabrielse; Index.

FOREWORD: The XXV IAHR Symposium on Hydraulic Machinery and Systems marks half a century tradition

NASA Astrophysics Data System (ADS)

Susan-Resiga, Romeo

2010-05-01

'Politehnica' of Timisoara in 1923 'It is not the walls that make a school, but the spirit living inside'. A particular trademark of the 'Politehnica' of Timisoara was the continuous effort to answer industrial problems by training the students not only on theoretical aspects but also in design and manufacturing, as well as in laboratory works. Developing modern laboratories, where students can observe and understand first hand the engineering applications along the years a priority for Timisoara 'Politehnica' University. The School of Hydraulic Machinery within the 'Politehnica' University of Timisoara was established in early 1930 by Professor Aurel Barglazan (1905-1960), and further developed by Professor Ioan Anton (born 1924), both members of the Romanian Academy. The Laboratory of Hydraulic Machines from Timisoara (LMHT) started back in 1928 in a small hut, with a test rig for Francis and Kaplan turbines manufactured by J M Voith. LMHT was continuously developed and was officially recognized in 1959 as being one of the leading research and developing laboratories in Romania. It was the foundation of the Romanian efforts of designing and manufacturing hydraulic turbines starting in 1960 at the Resita Machine Building Factory. Under the leadership of Professor Ioan Anton, the Timisoara School in Hydraulic Machinery has focused the basic and development research activities on the following main topics: (i) Turbine Hydrodynamics, (ii) Hydrofoil Cascade Hydrodynamics, (iii) Cavitation in Hydraulic Machines and Equipments, (iv) Scale-up Effects in Hydraulic Machines. With the establishment in the year 2000 of the National Center for Engineering of Systems with Complex Fluids, within the 'Politehnica' University of Timisoara, the research in turbomachinery hydrodynamics and cavitation included high performance computing for flows in hydraulic machines, as well as the development of novel technologies to mitigate the self-induced flow instabilities in hydraulic turbines operated

EDITORIAL: Fluctuations and noise in photonics and quantum optics: a special issue in memory of Hermann Haus

NASA Astrophysics Data System (ADS)

Abbott, Derek; Shapiro, Jeffrey H.; Yamamoto, Yoshihisa

2004-08-01

, USA Peter R Smith Loughborough University of Technology, UK Rodney S Tucker University of Melbourne, Australia Howard M Wiseman Griffith University, Brisbane, Australia Stuart A Wolf DARPA, Arlington, VA, USA Anton Zeilinger University of Vienna, Austria Xi-Cheng Zhang Rensselaer Polytechnic Institute, Troy, NY, USA

New National Telescope at La Silla - TRAPPIST to Scout the Sky and Uncover Exoplanets and Comets

NASA Astrophysics Data System (ADS)

2010-06-01

Geneva Observatory, Switzerland. The telescope is installed in the building that housed the old Swiss T70 telescope. Thanks to this collaboration, the whole project is on a fast track: it took only two years between taking the decision to build and first light. TRAPPIST will also be used for the study of southern comets. To this aim, the telescope is equipped with special large, high quality cometary filters, allowing astronomers to study regularly and in detail the ejection of several types of molecules by comets during their journey around the Sun. "With dozens of comets observed each year, this will provide us with a unique dataset, bringing important information about their nature," says Jehin. TRAPPIST is a lightweight 0.6-metre robotic telescope, fully automated and moving precisely across the sky at a high speed. The observing programme is prepared in advance and the telescope can perform a full night of observations unattended. A meteorological station monitors the weather continuously and decides to close the dome if necessary. Notes [1] A planetary transit occurs when a celestial body passes in front of its host star and blocks some of the star's light. This type of eclipse causes changes in the apparent brightness of the star and enables the planet's diameter to be measured. Combined with radial velocity measurements, it is also possible to deduce the mass and, hence, the density of the planet. More information TRAPPIST (TRAnsiting Planets and PlanetesImals Small Telescope) is a project led by the Department of Astrophysics, Geophysics and Oceanography (AGO) of the University of Liège (Belgium), in close collaboration with the Observatory of Geneva (Switzerland). TRAPPIST is mostly funded by the Belgian Fund for Scientific Research (FNRS) with the participation of the Swiss National Science Foundation (SNF). The team is composed of Emmanuël Jehin, Michaël Gillon, Pierre Magain, Virginie Chantry, Jean Manfroid, and Damien Hutsemékers (University of Li

The Secret Lives Of Galaxies Unveiled In Deep Survey

NASA Astrophysics Data System (ADS)

2003-06-01

South This increase in galaxy size is consistent with "bottom-up" models, where galaxies grow hierarchically, through mergers and accretion of smaller satellite galaxies. This is also consistent with the idea the sizes of galaxies match hand-in-glove to a certain fraction of the sizes of their dark-matter halos. Dark matter is an invisible form of mass that comprises most of the matter in the universe. The theory is dark matter essentially pooled into gravitational "puddles" in the early universe, then collected normal gas that quickly contracted to build star clusters and small galaxies. These dwarf galaxies merged piece-by-piece over billions of years to build the immense spiral and elliptical galaxies we see today. The Chandra observations amounted to a "high-energy core sample" of the early universe, allowing us to "study the history of black holes over almost the entire age of the universe," said Niel Brandt of Penn State University, a co-investigator on the Chandra GOODS team. One of the fascinating findings in this deepest X-ray image ever taken is the discovery of mysterious black holes, which have no optical counterparts. "We found seven mysterious sources that are completely invisible in the optical with Hubble," said Anton Koekemoer of the STScI, a co-investigator on both the Hubble and Chandra GOODS teams. "Either they are the most distant black holes ever detected, or they are less distant black holes that are the most dust enshrouded known, a surprising result as well." When comparing the HST and Chandra fields, astronomers also found active black holes in distant, relatively small galaxies were rarer than expected. This may be due to the effects of early generations of massive stars that exploded as supernovae, evacuating galactic gas and thus reducing the supply of gas needed to feed a super massive black hole. These and other results from the GOODS project will be published in a special issue of the Astrophysical Journal Letters, entirely devoted to the

REPORT OF RESEARCH ACCOMPLISHMENTS AND FUTURE GOALS HIGH ENERGY PHYSICS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wise, Mark B.; Kapustin, Anton N.; Schwarz, John Henry

. Areas of activity include: CDMS II data analysis, contributions to SuperCDMS Soudan operations and analysis, R&D towards SuperCDMS SNOLAB, development of a novel screener for radiocontamination (the BetaCage), and development of new WIMP detector concepts. Ren-Yuan Zhu leads the HEP crystal laboratory for the advanced detector R&D effort. The crystal lab is involved in development of novel scintillating crystals and has proposed several crystal based detector concepts for future HEP experiments at the energy and intensity frontiers. Its current research effort is concentrated on development of fast crystal scintillators with good radiation hardness and low cost. II) THEORETICAL PHYSICS The main theme of Sergei Gukov's current research is the relation between the geometry of quantum group invariants and their categorification, on the one hand, and the physics of supersymmetric gauge theory and string theory, on the other. Anton Kapustin's research spans a variety of topics in non-perturbative Quantum Field Theory (QFT). His main areas of interest are supersymmetric gauge theories, non-perturbative dualities in QFT, disorder operators, Topological Quantum Field Theory, and non-relativistic QFT. He is also interested in the foundations and possible generalizations of Quantum Mechanics. Hirosi Ooguri's current research has two main components. One is to find exact results in Calabi-Yau compactification of string theory. Another is to explore applications of the AdS/CFT correspondence. He also plans to continue his project with Caltech postdoctoral fellows on BPS spectra of supersymmetric gauge theories in diverse dimensions. John Preskill works on quantum information science. This field may lead to important future technologies, and also lead to new understanding of issues in fundamental physics John Schwarz has been exploring a number of topics in superstring theory/M-theory, supersymmetric gauge theory, and their AdS/CFT relationships. Much of the motivation for these

Sensitivity of ocean model simulation in the coastal ocean to the resolution of the meteorological forcing

NASA Astrophysics Data System (ADS)

Chen, Feng; Shapiro, Georgy; Thain, Richard

2013-04-01

Zatsepin , Valentina Khan, Valery Prostakishin , Tatiana Akivis , Vladimir Belokopytov , Anton Sviridov , and Vladimir Piotukh . 2011. Response of water temperature in the Black Sea to atmospheric forcing: the sensitivity study. Geophysical Research Abstracts. Vol. 13, EGU2011-933

PREFACE: International Conference on Topics in Astroparticle and Underground Physics (TAUP 2011)

NASA Astrophysics Data System (ADS)

Oberauer, Lothar; Raffelt, Georg; Wagner, Robert

2012-07-01

The 12th edition of the International Conference on Topics in Astroparticle and Underground Physics (TAUP 2011) was held 5-9 September 2011 in Munich (and for the first time in Germany). It was organized by the Max Planck Institute for Physics (MPP), the Technical University Munich (TUM) and the Cluster of Excellence 'Origin and Structure of the Universe'. The conference was held in the 'Künstlerhaus', a traditional downtown location for artistic festivities. The meeting attracted 317 participants (61 of which were women) from 29 countries, see figure below. The topics covered by the meeting were Cosmology and particle physics, Dark matter and its detection, Neutrino physics and astrophysics, Gravitational waves and High-energy astrophysics and cosmic rays, and the various interfaces between these areas. The scientific sessions consisted of five mornings of plenary talks, four afternoons of parallel sessions, and an evening poster session. The co-founder of the conference series, Alessandro Bottino, has decided to retire from the position of chairman of the TAUP Steering Committee after the completion of TAUP 2011. On behalf of all followers of this series, we thank him for having started these inspiring events and his many years of dedicated service. We thank all speakers, conveners and participants as well as the members of the organizing, steering and international advisory committee for making this a successful and memorable meeting. Lothar Oberauer, Georg Raffelt, Robert Wagner Proceedings editors Figure Committees International Advisory Committee G AntonUniversity of Erlangen E AprileColumbia University M Baldo-CeolinUniversity of Padova R BattistonUniversity of Perugia & INFN L BergströmUniversity Stockholm R BernabeiUniversity of Rome 'Tor Vergata' A BettiniLSC Canfranc P BinetruyAPC Paris J BlümerKarlsruhe Institute of Technology B CabreraStanford University A CaldwellMax Planck Institute for Physics M ChenQueens University E CocciaUniversity of Rome

PREFACE: EmQM13: Emergent Quantum Mechanics 2013

NASA Astrophysics Data System (ADS)

2014-04-01

these proceedings represent the talks of the invited speakers as written immediately after the symposium. The volume starts with a contribution by organizers Jan Walleczek and Gerhard Grössing, essentially explaining why emergent quantum mechanics, and other deterministic approaches to quantum theory, must be considered viable approaches in quantum foundations today. This is followed by the exposition of Stephen Adler's talk who introduced to a general audience key questions at the current frontiers of quantum mechanics during the opening evening (with the contents of his conference talk appearing elsewhere). The conference proceedings then continues with the presentations as given in their chronological order i.e. starting with the opening talk of the scientific program by Gerard 't Hooft. While the page number was restricted for all invited speakers, the paper by Jeff Tollaksen was given more space, as his invited collaborator Yakir Aharonov was unable to deliver a separate talk, in order to represent both contributions in one paper. Note that the talks of all speakers, including the talks of those who could not be represented in this volume (M. Arndt, B. Braverman, C. Brukner, S. Colin, Y. Couder, B. Poirier, A. Steinberg, G. Weihs and H. Wiseman) are freely available on the conference website as video presentations (http://www.emqm13.org). The organizers wish to express their gratitude to Siegfried Fussy and Herbert Schwabl from AINS for the organizational support. The organizers also wish to thank Bruce Fetzer, President and CEO, John E. Fetzer Memorial Trust, and the Members of the Board of Trustees, for their strong support and for funding this symposium. We also wish to thank the Austrian Academy of Sciences for allowing the symposium to be held on their premises, and Anton Zeilinger, President of the Austrian Academy of Sciences, for his welcome address. The expertise of the Members of the Scientific Advisory Board of the EmQM13 symposium, Ana Maria Cetto

Computational study of pristine and titanium-doped sodium alanates for hydrogen storage applications

NASA Astrophysics Data System (ADS)

Dathar, Gopi Krishna Phani

The emphasis of this research is to study and elucidate the underlying mechanisms of reversible hydrogen storage in pristine and Ti-doped sodium aluminum hydrides using molecular modeling techniques. An early breakthrough in using complex metal hydrides as hydrogen storage materials is from the research on sodium alanates by Bogdanovic et al., in 1997 reporting reversible hydrogen storage is possible at moderate temperatures and pressures in transition metal doped sodium alanates. Anton reported titanium salts as the best catalysts compared to all other transition metal salts from his further research on transition metal doped sodium alanates. However, a few questions remained unanswered regarding the role of Ti in reversible hydrogen storage of sodium alanates with improved thermodynamics and kinetics of hydrogen desorption. The first question is about the position of transition metal dopants in the sodium aluminum hydride lattice. The position is investigated by identifying the possible sites for titanium dopants in NaAlH4 lattice and studying the structure and dynamics of possible compounds resulting from titanium doping in sodium alanates. The second question is the role of titanium dopants in improved thermodynamics of hydrogen desorption in Ti-doped NaAlH4. Though it is accepted in the literature that formation of TiAl alloys (Ti-Al and TiAl3) is favorable, reaction pathways are not clearly established. Furthermore, the source of aluminum for Ti-Al alloy formation is not clearly understood. The third question in this area is the role of titanium dopants in improved kinetics of hydrogen absorption and desorption in Ti-doped sodium alanates. This study is directed towards addressing the three longstanding questions in this area. Thermodynamic and kinetic pathways for hydrogen desorption in pristine NaAlH4 and formation of Ti-Al alloys in Ti-doped NaAlH 4, are elucidated to understand the underlying mechanisms of hydrogen desorption. Density functional theory

PREFACE: EmerQuM 11: Emergent Quantum Mechanics 2011 (Heinz von Foerster Congress)

NASA Astrophysics Data System (ADS)

Grössing, Gerhard

2012-05-01

These proceedings comprise the plenary lectures and poster contributions of the 'Heinz von Foerster Conference 2011' on Emergent Quantum Mechanics (EmerQuM11), which was held at the University of Vienna, 11-13 November 2011. With the 5th International Heinz von Foerster Conference convened at the occasion of von Foerster's 100th birthday, the organizers opted for a twin conference to take place at the Large and Small Ceremonial Halls of the University's main building, respectively. The overall topic was chosen as 'Self-Organization and Emergence', a topic to which von Foerster was an early contributor. While the first conference ('Self-Organization and Emergence in Nature and Society') addressed a more general audience, the second one ('Emergent Quantum Mechanics') was intended as a specialist meeting with a contemporary topic that could both serve as an illustration of von Foerster's intellectual heritage and, more generally, point towards future directions in physics. We thus intended to bring together many of those physicists who are interested in or are working on attempts to understand quantum mechanics as emerging from a suitable classical (or, more generally, deeper level) physics. EmerQuM11 was organized by the Austrian Institute for Nonlinear Studies (AINS), with essential support from the Wiener Institute for Social Science Documentation and Methodology (WISDOM), the Department of Contemporary History at the University of Vienna, and the Heinz von Foerster-Gesellschaft. There were a number of individuals who contributed to the smooth course of our meeting and whom I would like to sincerely thank: Christian Bischof, Thomas Elze, Marianne Ertl, Gertrud Hafner, Werner Korn, Angelika Krawanja, Florian Krug and his team, Sonja Lang, Albert Müller, Ilse Müller, Irene Müller, Karl Müller, Armin Reautschnig, Marion Schirrmacher, Anton Staudinger, Roman Zlabinger, and, last but not least, my AINS colleagues Siegfried Fussy, Herbert Schwabl and Johannes Mesa

Committees

NASA Astrophysics Data System (ADS)

2012-11-01

Leadership Team of the IAHR Committee for Hydraulic Machinery and Systems Eduard EGUSQUIZA, UPC Barcelona, Spain, Chair François AVELLAN, EPFL-LMH, Switzerland, Past Chair Richard K FISHER, Voith Hydro Inc., USA, Past Chair Fidel ARZOLA, Edelca, Venezuela Michel COUSTON, Alstom Hydro, France Niklas DAHLBÄCKCK, Vatenfall, Sweden Normand DESY, Andritz VA TECH Hydro Ltd., Canada Chisachi KATO, University of Tokyo, Japan Andrei LIPEJ, Turboinstitut, Slovenija Torbjørn NIELSEN, NTNU, Norway Romeo SUSAN-RESIGA, 'Politehnica' University Timisoara, Romania Stefan RIEDELBAUCH, Stuggart University, Germany Albert RUPRECHT, Stuttgart University, Germany Qing-Hua SHI, Dong Fang Electrical Machinery Co., China Geraldo TIAGO, Universidade Federal de Itajubá, Brazil International Advisory Committee Shouqi YUAN (principal) Jiangsu University China QingHua SHI (principal) Dong Fang Electrical Machinery Co. China Fidel ARZOLA EDELCA Venezuela Thomas ASCHENBRENNER Voith Hydro GmbH & Co. KG Germany Anton BERGANT Litostroj Power doo Slovenia B C BHAOYAL Research & Technology Centre India Hermod BREKKE NTNU Norway Stuart COULSON Voith Hydro Inc. USA Paul COOPER Fluid Machinery Research Inc USA V A DEMIANOV Power Machines OJSC Russia Bart van ESCH Technische Universiteit Eindhoven Netherland Arno GEHRER Andritz Hydro Graz Austria Akira GOTO Ebara Corporation Japan Adiel GUINZBURG The Boeing Company USA D-H HELLMANN KSB AG Germany Ashvin HOSANGADI Combustion Research and Flow Technology USA Byung-Sun HWANG Korea Institute of Material Science Korea Toshiaki KANEMOTO Kyushu Institute of Technology Japan Mann-Eung KIM Korean Register of Shipping Korea Jiri KOUTNIK Voith Hydro GmbH & Co. KG Germany Jinkook LEE Eaton Corporation USA Young-Ho LEE Korea Maritime University Korea Woo-Seop LIM Hyosung Goodsprings Inc Korea Jun MATSUI Yokohama National University Japan Kazuyoshi Mitsubishi H I Ltd, Japan MIYAGAWA Christophe NICOLET Power Vision Engineering Srl Switzerland Maryse PAGE Hydro

International Agreement Will Advance Radio Astronomy

NASA Astrophysics Data System (ADS)

2007-12-01

Two of the world's leading astronomical institutions have formalized an agreement to cooperate on joint efforts for the technical and scientific advancement of radio astronomy. The National Radio Astronomy Observatory (NRAO) in the United States and the Max-Planck Institute for Radioastronomy (MPIfR) in Germany concluded a Memorandum of Understanding outlining planned collaborative efforts to enhance the capabilities of each other's telescopes and to expand their cooperation in scientific research. The VLBA The VLBA CREDIT: NRAO/AUI/NSF In the first project pursued under this agreement, the MPIfR will contribute $299,000 to upgrade the continent-wide Very Long Baseline Array's (VLBA) capability to receive radio emissions at a frequency of 22 GHz. This improvement will enhance the VLBA's scientific productivity and will be particularly important for cutting-edge research in cosmology and enigmatic cosmic objects such as gamma-ray blazars. "This agreement follows many years of cooperation between our institutions and recognizes the importance of international collaboration for the future of astronomical research," said Fred K.Y. Lo, NRAO Director. "Our two institutions have many common research goals, and joining forces to keep all our telescopes at the forefront of technology will be highly beneficial for the science," said Anton Zensus, Director at MPIfR. In addition to the VLBA, the NRAO operates the Very Large Array (VLA) in New Mexico and the Robert C. Byrd Green Bank Telescope (GBT) in West Virginia. The MPIfR operates the 100-meter Effelsberg Radio Telescope in Germany and the 12-meter APEX submillimeter telescope in 5100 m altitude in the Cilean Atacama desert (together with the European Southern Observatory and the Swedish Onsala Space Observatory). With the 100-meter telescope, it is part of the VLBA network in providing transatlantic baselines. Both institutions are members of a global network of telescopes (the Global VLBI Network) that uses simultaneous

PREFACE: ARENA 2006—Acoustic and Radio EeV Neutrino detection Activities

NASA Astrophysics Data System (ADS)

Thompson, Lee

2007-06-01

The International Conference on Acoustic and Radio EeV Neutrino Activities, ARENA 2006 was jointly hosted by the Universities of Northumbria and Sheffield at the City of Newcastle Campus of the University of Northumbria in June 2006. ARENA 2006 was the latest in a series of meetings which have addressed, either separately or jointly, the use of radio and acoustic sensors for the detection of highly relativistic particles. Previous successful meetings have taken place in Los Angeles (RADHEP, 2000), Stanford (2003) and DESY Zeuthen (ARENA 2005). A total of 50 scientists from across Europe, the US and Japan attended the conference presenting status reports and results from a number of projects and initiatives spread as far afield as the Sweden and the South Pole. The talks presented at the meeting and the proceedings contained herein represent a `snapshot' of the status of the fields of acoustic and radio detection at the time of the conference. The three day meeting also included two invited talks by Dr Paula Chadwick and Dr Johannes Knapp who gave excellent summaries of the related astroparticle physics fields of high energy gamma ray detection and high energy cosmic ray detection respectively. As well as a full academic agenda there were social events including a Medieval themed conference banquet at Lumley Castle and a civic reception kindly provided by the Lord Mayor of Newcastle and hosted at the Mansion House. Thanks must go to the International Advisory Board members for their input and guidance, the Local Organising Committee for their hard work in bringing everything together and finally the delegates for the stimulating, enthusiastic and enjoyable spirit in which ARENA 2006 took place. Lee Thompson

International Advisory Board