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Sample records for apache ii child-pugh

  1. Laparoscopic Cholecystectomy in Child-Pugh Class C Cirrhotic Patients

    PubMed Central

    Iapichino, Giuliano; Melita, Giuseppinella; Lorenzini, Cesare; Cucinotta, Eugenio

    2005-01-01

    Objectives: This study aimed to determine whether laparoscopic cholecystectomy is a safe and advisable procedure in Child-Pugh C cirrhotic patients with symptomatic cholelithiasis. Methods: The records of 42 laparoscopic cholecystectomies performed between January 1995 and February 2004 in patients with Child-Pugh A, B, and C cirrhosis were retrospectively reviewed, focusing on the 4 patients with Child-Pugh C cirrhosis. Results: Among the 38 Child-Pugh A and B patients, no deaths occurred. In this group, only 1 Child-Pugh B cirrhotic patient required blood transfusion, and postoperative morbidity occurred in 10 patients including hemorrhage, wound infection, intraabdominal collection, and cardiopulmonary complications (morbidity rate 26%). The mean postoperative stay was 5 days (range, 3 to 13). The indication for surgery in the 4 Child-Pugh C patients was acute cholecystitis. In this group, 2 deaths occurred for severe liver failure in 1 case and for sepsis in the other. One patient developed heavy gallbladder bed bleeding, and a second operation was necessary to control the hemorrhage. The morbidity rate was 75%. Only 1 patient had no complications. The mean postoperative stay was 10 days (range, 4 to 17). Conclusions: Laparoscopic cholecystectomy is a safe procedure in well-selected Child-Pugh A and B cirrhotic patients indicated for surgery, but it is a very high-risk procedure in Child-Pugh C patients. Indications for surgery in Child-Pugh C patients should be evaluated very carefully and surgery should be avoided unless the patient needs an emergency cholecystectomy for acute cholecystitis. Child-Pugh C cirrhotic patients might better benefit from percutaneous drainage of the gallbladder. PMID:16121878

  2. Apache, Vol. II.

    ERIC Educational Resources Information Center

    Bodiroga, Ronald, Comp.; And Others

    The short stories, poems, songs, and cultural descriptions about American Indians (volume 2 of two) are the result of a combined effort of the 7th grade students of Rice School District (Sacaton, Arizona), their teacher, and the parents and friends of the students of the San Carlos Apache Indian Reservation (Arizona). The 24 student contributors…

  3. Safety and efficacy of sorafenib in patients with Child-Pugh B advanced hepatocellular carcinoma

    PubMed Central

    DA FONSECA, LEONARDO GOMES; BARROSO-SOUSA, ROMUALDO; BENTO, AFONSO DA SILVA ALVES; BLANCO, BRUNA PACCOLA; VALENTE, GABRIEL LUIS; PFIFFER, TULIO EDUARDO FLESCH; HOFF, PAULO MARCELO; SABBAGA, JORGE

    2015-01-01

    Sorafenib demonstrated a survival benefit in the treatment of advanced hepatocellular carcinoma (HCC) in phase III trials. However, almost all the patients included in those trials exhibited well-preserved liver function (Child-Pugh A). The aim of this study was to describe our experience with sorafenib in Child-Pugh B HCC patients. A database of patients with advanced HCC treated with sorafenib was retrospectively evaluated. The median overall survival of Child-Pugh B patients (n=20) was 2.53 months [95% confidence interval (CI): 0.33–5.92 months] and of Child-Pugh A patients (n=100) 9.71 months (95% CI: 6.22–13.04). Child-Pugh B patients had a significantly poorer survival compared to Child-Pugh A patients (P=0.002). The toxicities were similar between the two groups. Metastasis, vascular invasion and α-fetoprotein level >1,030 ng/ml were not associated with survival among Child-Pugh B patients (P=0.281, 0.189 and 0.996, respectively). Although the survival outcomes were worse in Child-Pugh B patients treated with sorafenib, the toxicity profile was manageable. Therefore, there remains the question of whether to treat this subgroup of patients and more data are required to define the role of sorafenib in the context of liver dysfunction. PMID:26171182

  4. Predicting outcomes in organophosphate poisoning based on APACHE II and modified APACHE II scores.

    PubMed

    Eizadi-Mood, N; Saghaei, M; Jabalameli, M

    2007-07-01

    The aim of this study was to evaluate the scores of the Acute Physiology and Chronic Health Evaluation (APACHE) II and a modified APACHE II system (MAS), without parameters of biochemical tests; and to find prognostic value of individual elements of the APACHE II and MAS in predicting outcomes in organophosphate (OP) poisoning. Data were collected from 131 patients. The median (25th-75th percentiles) of APACHE II score for survivors without intubation were found to be lower than those of non survivors or survivors with intubation and ventilation, [4 (1-7); versus 17.5 (7.8-29), and 13.5 (7.8-16.3)]. Logistic regression analysis identified white blood cell (WBC), potassium, Glasgow coma scale (GCS), age and sodium in APACHE II; GCS and mean arterial pressure in MAS system as prognostically valuable. There was no statistically significance difference between APACHE II and MAS scores in terms of area under Receiver Operating Characteristic Curve [(0.902, 95% confidence interval: (0.837-0.947) for APACHE II), and (0.892, 95% confidence interval: (0.826-0.940) for MAS); P=0.74) to predict need for intubation. It is concluded usage of MAS facilitates the prognostication of the OP poisoned patients due to simplicity, less time-consuming and effectiveness in an emergency situation.

  5. Mortality after cardiac surgery in patients with liver cirrhosis classified by the Child-Pugh score.

    PubMed

    Jacob, Kirolos A; Hjortnaes, Jesper; Kranenburg, Guido; de Heer, Frederiek; Kluin, Jolanda

    2015-04-01

    Liver cirrhosis is a known risk factor for postoperative mortality in patients undergoing cardiac surgery. Clinical assessment of liver cirrhosis using the widely accepted Child-Pugh (CP) score is thus vital for evaluation of surgical options and perioperative care. However, detailed mortality rates as a consequence of liver cirrhosis are unclear. This review aimed to stratify the risk of short-term (<30 days) and overall (up to 10 years) mortality after cardiac surgery in patients with liver cirrhosis, classified by the CP score. Thus, PubMed, Embase, CINAHL and the Cochrane Library were systematically reviewed by two independent investigators for studies published up to February 2014, in which mortality in cirrhotic patients, classified by the CP classification, undergoing cardiac surgery was evaluated postoperatively. A total of 993 articles were identified. After critical appraisal of 21 articles, 19 were selected for final analysis. Weighted short-term mortality of cirrhotic patients undergoing cardiac surgery was 19.3% [95% confidence interval (CI): 16.4-22.5%]. Across the different CP groups, short-term mortality appeared to be 9.0% (95% CI: 6.6-12.2%), 37.7% (95% CI: 30.8-44.3%) and 52.0% (95% CI: 33.5-70.0%) in Groups A, B and C, respectively. Weighted overall mortality within 1 year was 42.0% (95% CI: 36.0-48.3%) in all cirrhotic patients. Subdivided in groups, overall mortality within that 1 year was 27.2% (95% CI: 20.9-34.7%), 66.2% (95% CI: 54.3-76.3%) and 78.9% (95% CI: 56.1-92.1%) in Groups A, B and C, respectively. In conclusion, short-term mortality is considerably increased in patients with liver cirrhosis CP class B and C. Overall mortality is significantly high in all classes of liver cirrhosis.

  6. Use of APACHE II and SAPS II to predict mortality for hemorrhagic and ischemic stroke patients.

    PubMed

    Moon, Byeong Hoo; Park, Sang Kyu; Jang, Dong Kyu; Jang, Kyoung Sool; Kim, Jong Tae; Han, Yong Min

    2015-01-01

    We studied the applicability of the Acute Physiology and Chronic Health Evaluation II (APACHE II) and Simplified Acute Physiology Score II (SAPS II) in patients admitted to the intensive care unit (ICU) with acute stroke and compared the results with the Glasgow Coma Scale (GCS) and National Institutes of Health Stroke Scale (NIHSS). We also conducted a comparative study of accuracy for predicting hemorrhagic and ischemic stroke mortality. Between January 2011 and December 2012, ischemic or hemorrhagic stroke patients admitted to the ICU were included in the study. APACHE II and SAPS II-predicted mortalities were compared using a calibration curve, the Hosmer-Lemeshow goodness-of-fit test, and the receiver operating characteristic (ROC) curve, and the results were compared with the GCS and NIHSS. Overall 498 patients were included in this study. The observed mortality was 26.3%, whereas APACHE II and SAPS II-predicted mortalities were 35.12% and 35.34%, respectively. The mean GCS and NIHSS scores were 9.43 and 21.63, respectively. The calibration curve was close to the line of perfect prediction. The ROC curve showed a slightly better prediction of mortality for APACHE II in hemorrhagic stroke patients and SAPS II in ischemic stroke patients. The GCS and NIHSS were inferior in predicting mortality in both patient groups. Although both the APACHE II and SAPS II systems can be used to measure performance in the neurosurgical ICU setting, the accuracy of APACHE II in hemorrhagic stroke patients and SAPS II in ischemic stroke patients was superior.

  7. Comparison of two simplified severity scores (SAPS and APACHE II) for patients with acute myocardial infarction.

    PubMed

    Moreau, R; Soupison, T; Vauquelin, P; Derrida, S; Beaucour, H; Sicot, C

    1989-05-01

    The Simplified Acute Physiology Score (SAPS), the Acute Physiology and Chronic Health Evaluation II (APACHE II), the Acute Physiology Score (APS), and the Coronary Prognostic Index (CPI), calculated within the first 24 h of ICU admission, were compared in 76 patients with acute myocardial infarction (AMI). Sixteen (21%) patients subsequently died in the ICU. The nonsurvivors had significantly higher SAPS, APACHE II, and CPI scores than the survivors. ROC curves drawn for each severity index were in a discriminating position. There were no significant differences either between the areas under the ROC curves drawn for SAPS, APACHE II, and CPI, or between the overall accuracies of these indices. APS provided less homogeneous information. We conclude that SAPS and APACHE II, two severity indices which are easy to use, assess accurately the short-term prognosis, i.e., the ICU outcome, of patients with AMI. PMID:2707010

  8. Evaluation of nosocomial infection risk using APACHE II scores in the neurological intensive care unit.

    PubMed

    Li, Hai-Ying; Li, Shu-Juan; Yang, Nan; Hu, Wen-Li

    2014-08-01

    To evaluate the feasibility and accuracy of using the Acute Physiology, Age and Chronic Health Evaluation II (APACHE II) scoring system for predicting the risk of nosocomial infection in the neurological intensive care unit (NICU), 216 patients transferred to NICU within 24hours of admission were retrospectively evaluated. Based on admission APACHE II scores, they were classified into three groups, with higher APACHE II scores representing higher infectious risk. The device utilization ratios and device-associated infection ratios of NICU patients were analyzed and compared with published reports on patient outcome. Statistical analysis of nosocomial infection ratios showed obvious differences between the high-risk, middle-risk and low-risk groups (p<0.05). The area under the receiver operating characteristic curve of the APACHE II model in predicting the risk of nosocomial infection was 0.81, which proved to be reliable and consistent with the expectation. In addition, we found statistical differences in the duration of hospital stay (patient-days) and device utilization (device-days) between different risk groups (p<0.05). Thus the APACHE II scoring system was validated in predicting the risk of nosocomial infection, duration of patient-days and device-days, and providing accurate assessment of patients' condition, so that appropriate prevention strategies can be implemented based on admission APACHE II scores.

  9. Performance assessment of the SOFA, APACHE II scoring system, and SAPS II in intensive care unit organophosphate poisoned patients.

    PubMed

    Kim, Yong Hwan; Yeo, Jung Hoon; Kang, Mun Ju; Lee, Jun Ho; Cho, Kwang Won; Hwang, SeongYoun; Hong, Chong Kun; Lee, Young Hwan; Kim, Yang Weon

    2013-12-01

    This study assessed the ability of the Sequential Organ Failure Assessment (SOFA) and Acute Physiology, Chronic Health Evaluation (APACHE) II scoring systems, as well as the Simplified Acute Physiology Score (SAPS) II method to predict group mortality in intensive care unit (ICU) patients who were poisoned with organophosphate. The medical records of 149 organophosphate poisoned patients admitted to the ICU from September 2006 to December 2012 were retrospectively examined. The SOFA, APACHE II, and SAPS II were calculated based on initial laboratory data in the Emergency Department, and during the first 24 hr of ICU admission. The probability of death was calculated for each patient based on the SOFA score, APACHE II score, and SAPS II equations. The ability to predict group mortality by the SOFA score, APACHE II score, and SAPS II method was assessed using two by two decision matrices and receiver operating characteristic (ROC) curve analysis. A total of 131 patients (mean age, 61 yr) were enrolled. The sensitivities, specificities, and accuracies were 86.2%, 82.4%, and 83.2% for the SOFA score, respectively; 65.5%, 68.6%, and 67.9% for the APACHE II scoring system, respectively; and 86.2%, 77.5%, and 79.4% for the SAPS II, respectively. The areas under the curve in the ROC curve analysis for the SOFA score, APACHE II scoring system, and SAPS II were 0.896, 0.716, and 0.852, respectively. In conclusion, the SOFA, APACHE II, and SAPS II have different capability to discriminate and estimate early in-hospital mortality of organophosphate poisoned patients. The SOFA score is more useful in predicting mortality, and easier and simpler than the APACHE II and SAPS II.

  10. Performance Assessment of the SOFA, APACHE II Scoring System, and SAPS II in Intensive Care Unit Organophosphate Poisoned Patients

    PubMed Central

    Kim, Yong Hwan; Yeo, Jung Hoon; Kang, Mun Ju; Cho, Kwang Won; Hwang, SeongYoun; Hong, Chong Kun; Lee, Young Hwan; Kim, Yang Weon

    2013-01-01

    This study assessed the ability of the Sequential Organ Failure Assessment (SOFA) and Acute Physiology, Chronic Health Evaluation (APACHE) II scoring systems, as well as the Simplified Acute Physiology Score (SAPS) II method to predict group mortality in intensive care unit (ICU) patients who were poisoned with organophosphate. The medical records of 149 organophosphate poisoned patients admitted to the ICU from September 2006 to December 2012 were retrospectively examined. The SOFA, APACHE II, and SAPS II were calculated based on initial laboratory data in the Emergency Department, and during the first 24 hr of ICU admission. The probability of death was calculated for each patient based on the SOFA score, APACHE II score, and SAPS II equations. The ability to predict group mortality by the SOFA score, APACHE II score, and SAPS II method was assessed using two by two decision matrices and receiver operating characteristic (ROC) curve analysis. A total of 131 patients (mean age, 61 yr) were enrolled. The sensitivities, specificities, and accuracies were 86.2%, 82.4%, and 83.2% for the SOFA score, respectively; 65.5%, 68.6%, and 67.9% for the APACHE II scoring system, respectively; and 86.2%, 77.5%, and 79.4% for the SAPS II, respectively. The areas under the curve in the ROC curve analysis for the SOFA score, APACHE II scoring system, and SAPS II were 0.896, 0.716, and 0.852, respectively. In conclusion, the SOFA, APACHE II, and SAPS II have different capability to discriminate and estimate early in-hospital mortality of organophosphate poisoned patients. The SOFA score is more useful in predicting mortality, and easier and simpler than the APACHE II and SAPS II. PMID:24339715

  11. Predicting hospital mortality using APACHE II scores in neurocritically ill patients: a prospective study.

    PubMed

    Su, Ying-Ying; Li, Xia; Li, Si-jie; Luo, Rong; Ding, Jian-ping; Wang, Lin; Cao, Gui-hua; Wang, Dong-yu; Gao, Jin-xia

    2009-09-01

    Four versions of Acute Physiology and Chronic Health Evaluation are limited in predicting hospital mortality for neurocritically ill patients. This prospective study aimed to develop and assess the accuracy of a modified APACHE II model in predicting mortality in neurologic intensive care unit (N-ICU). A total of 653 patients entered the study. APACHE II scores on admission, and worst 24-, 48-, and 72-h scores were obtained. Neurologic diagnoses on admission were classified into five categories: cerebral infarction, intracranial hemorrhage, neurologic infection, neuromuscular disease, and other neurologic diseases. We developed a modified APACHE II model based on the variables of the 72-h APACHE II score and disease category using a multivariate logistic regression procedure to estimate probability of death. We assessed the calibration and discrimination of the modified APACHE II model using the Hosmer-Lemeshow goodness-of-fit chi-squared statistic and area under the receiver operating characteristic curve (AU-ROC). The modified APACHE II model had good discrimination (AU-ROC = 0.88) and calibration (Hosmer-Lemeshow statistic: chi (2) = 3.707, P = 0.834). The discrimination of the 72-h APACHE II score for cerebral infarction, intracerebral hemorrhage, and neurologic infection was satisfactory, with AU-ROC of 0.858, 0.863, and 1.000, respectively, but it was poor in discriminating for the categories of other neurologic diseases and neuromuscular disease. The results showed that our modified APACHE II model can accurately predict hospital mortality for patients in N-ICU. It is more applicable to clinical practice than the previous model because of its simplicity and ease of use.

  12. APACHE II: preliminary report on 100 intensive care unit cases in University Hospital, Kuala Lumpur.

    PubMed

    Teoh, G S; Mah, K K; abd Majid, S; Streram; Yee, M K

    1991-03-01

    A good overall assessment of the severity of illnesses of patients admitted to a general intensive care unit (ICU) is not without problems. The APACHE (acute physiology and chronic health evaluation) prognostic scoring system enables us to stratify acutely ill patients and compare efficiency of ICU therapy in different hospitals. This preliminary study carried out on 100 consecutive admissions to the ICU in University Hospital, Kuala Lumpur showed the spectrum of ICU admissions and the direct relationship between APACHE II score and mortality.

  13. Correlation of APACHE II and SOFA scores with length of stay in various surgical intensive care units.

    PubMed

    Milić, Morena; Goranović, Tatjana; Holjevac, Jadranka Katancić

    2009-09-01

    The aim of this study was to evaluate the usefulness of using Acute Physiology and Chronic Health Evaluation (APACHE) II score and Sequential Organ Failure Assessment (SOFA) score as the predictors of length of stay (LOS) in various surgical intensive care units (ICUs) and to test the hypothesis that the significance of scoring for predicting LOS is greater in specialized surgical ICUs. We scored patients in a non-specialized general surgical ICU (n = 328) and in a specialized cardiosurgical ICU (n = 158) consecutively on admission (APACHE II-1st day; SOFA-1st day) and on third day of stay (APACHE II-3rd day; SOFA-3rd day) in a 4-month period. LOS and APACHE II/SOFA scores were significantly correlated both on admission and on third day of stay in the general surgical ICU (APACHE II-1st day r = 0.289; SOFA-1st day r = 0.306; APACHE II-3rd day r = 0.728; SOFA-3rd day r = 0.725). LOS and APACHE II on admission were not significantly correlated in the cardiosurgical ICU (APACHE II-1st day r = 0.092), while SOFA on admission and APACHE II and SOFA on third day were significantly correlated (SOFA-1st day r = 0.258; APACHE II-3rd day r = 0.716; SOFA-3rd day r = 0.719). Usefulness of scoring for predicting LOS in ICU varied between different surgical ICUs. Contrary to our hypothesis, scoring had greater value for predicting LOS in the non-specialized general surgical ICU. APACHE II score on admission had no value for predicting LOS in the cardiosurgical ICU.

  14. QT dispersion and prognostication of the outcome in acute cardiotoxicities: A comparison with SAPS II and APACHE II scoring systems.

    PubMed

    Hassanian-Moghaddam, Hossein; Amiri, Hassan; Zamani, Nasim; Rahimi, Mitra; Shadnia, Shahin; Taherkhani, Maryam

    2014-06-01

    We aimed to evaluate the efficacy of QT dispersion (QTD) in determining the outcome of the patients poisoned by cardiotoxic medications and toxins. Patients who referred to our emergency department (ED) due to acute toxicity with any cardiotoxic medication or toxin and were admitted to medical toxicology intensive care unit (MTICU) were enrolled into the study. A questionnaire containing the demographic characteristics, vital signs, laboratory tests, electrocardiographic (ECG) parameters of the first ECG taken on MTICU or ED admission, simplified acute physiology score (SAPS), and acute physiology and chronic health evaluation (APACHE) score was filled for every single patient. QTD was manually calculated. The patients were divided into two groups of survivors and non-survivors and compared. Although QTD was not significantly different between the survivors and non-survivors (P = 0.8), SAPS II and APACHE II score were so. SAPS and APACHE had the highest sensitivity and specificity in determining the patients' mortality, respectively. SAPS had the highest sensitivity, and QTD had the highest specificity in predicting the later development of the complications. SAPS II and APACHE II scoring systems are the best systems for prognostication of death in patients with acute cardiotoxic medication-induced poisonings. QTD can be successfully used for the prediction of complications.

  15. Profile and severity of the patients of intensive care units: prospective application of the APACHE II index.

    PubMed

    De Freitas, Eliane Regina Ferreira Sernache

    2010-01-01

    This study aimed to understand the profile and severity of patients in physiotherapy treatment after their admission to the intensive care unit (ICU) by applying the APACHE II index. One hundred and forty six subjects, with a mean age of 60.5 +/- 19.2 years, were evaluated. The APACHE II index was applied in the first 24 hours to evaluate the severity and mortality risk score. Patients were monitored until hospital discharge or death. The mean APACHE II score was 20+/-7.3 with an estimated risk of death of 32.4% and observed mortality of 58.2%. The mean hospital stay was 27.8+/-25.2 days. The patients in physiotherapy at the institution studied were predominantly male, elderly, from the emergency service for treatment (non-surgical), and had clear severity, suggested by the APACHE II score and the observed mortality.

  16. Liver cirrhosis grading Child-Pugh class B: a Goliath to challenge in laparoscopic liver resection?—prior experience and matched comparisons

    PubMed Central

    Liang, Xiao; Yu, Tunan; Liang, Yuelong; Jing, Renan; Jiang, Wenbing; Li, Jianbo; Ying, Hanning

    2015-01-01

    Background Laparoscopic hepatectomy (LH) is highly difficult in the background of liver cirrhosis. In this case series, we aimed to summarize our prior experience of LH in liver cirrhosis grading Child-Pugh class B. Methods In the LH database of Sir Run Run Shaw Hospital in Zhejiang, China, patients who were pathologically diagnosed with cirrhosis and graded as Child-Pugh class B or C were reviewed. Results Five patients grading Child B were included. There was no Child C case in our LH database. For included cases, median blood loss (BL) was 800 (range, 240-1,000) mL, median operative time was 135 (range, 80-170) minutes, and median length of hospital stay was 9 (range, 7-15) days. Forty percent (2/5) of patients was converted to open. The postoperative complication (PC) rate was 20.0% (1/5). When these Child B cases were compared with Child A cases undergoing LH, there was no statistical significance in BL, complication rate, operative time, open rate and hospital stay (HS) (P>0.05). This finding was confirmed by two ways of matched comparisons (a 1:2 comparison based on age and gender, and a 1:1 propensity score matching). Conclusions Although relevant literatures had suggested feasibility of LH in cirrhotic cases grading Child A, this study was the first one to discuss the value of LH in Child B cases. Our prior experience showed that in selected patients, LH in Child B patients had the potential to be as safe as in Child A cases. The efficacy of LH in Child C patients needs further exploration. PMID:26734623

  17. Liver Lobe Based Multi-Echo Gradient Recalled Echo T2*-Weighted Imaging in Chronic Hepatitis B-Related Cirrhosis: Association with the Presence and Child-Pugh Class of Cirrhosis

    PubMed Central

    Wang, Dan; Chen, Tian-wu; Zhang, Xiao-ming; Li, Jie; Zeng, Nan-lin; Li, Li; Tang, Yu-lian; Huang, Yu-cheng; Li, Rui; Chen, Fan; Chen, Yan-li

    2016-01-01

    Purpose To investigate whether liver lobe based T2* values measured on gradient recalled echo T2*-weighted imaging are associated with the presence and Child-Pugh class of hepatitis B-related cirrhosis. Methods Fifty-six patients with hepatitis B-related cirrhosis and 23 healthy control individuals were enrolled in this study and underwent upper abdominal T2*-weighted magnetic resonance imaging. T2* values of the left lateral lobe (LLL), left medial lobe (LML), right lobe (RL) and caudate lobe (CL) were measured on T2*-weighted imaging. Statistical analyses were performed to determine the association between liver lobe based T2* values and the presence and Child-Pugh class of cirrhosis. Results The T2* values of the LLL, LML and RL decreased with the progression of cirrhosis from Child-Pugh class A to C (r = -0.231, -0.223, and -0.395, respectively; all P < 0.05), except that of the CL (r = -0.181, P > 0.05). To a certain extent, Mann-Whitney U tests with Bonferroni correction for multigroup comparisons showed that the T2* values of the LLL, LML and RL could distinguish cirrhotic liver from healthy liver (all P < 0.05), whereas the T2* values of the CL could not (P > 0.05). Receiver operating characteristic analysis demonstrated that the T2* value of the RL could best distinguish cirrhosis from healthy liver, with an area under the receiver operating characteristic curve (AUC) of 0.713 among T2* values of the liver lobes, and that only the T2* value of the RL could distinguish Child-Pugh class C from A-B, with an AUC of 0.697 (all P < 0.05). Conclusion The T2* value of the RL can be associated with the presence and Child-Pugh class of hepatitis B-related cirrhosis. PMID:27171422

  18. APACHE II score, rather than cardiac function, may predict poor prognosis in patients with stress-induced cardiomyopathy.

    PubMed

    Joe, Byung-Hyun; Jo, Uk; Kim, Hyun-Soo; Park, Chang-Bum; Hwang, Hui-Jeong; Sohn, Il-Suk; Jin, Eun-Sun; Cho, Jin-Man; Park, Jeong-Hwan; Kim, Chong-Jin

    2012-01-01

    While the disease course of stress-induced cardiomyopathy (SIC) is usually benign, it can be fatal. The prognostic factors to predict poorer outcome are not well established, however. We analyzed the Acute Physiology And Chronic Health Evaluation (APACHE) II score to assess its value for predicting poor prognosis in patients with SIC. Thirty-seven consecutive patients with SIC were followed prospectively during their hospitalization. Clinical factors, including APACHE II score, coronary angiogram, echocardiography and cardiac enzymes at presentation were analyzed. Of the 37 patients, 27 patients (73%) were women. The mean age was 66.1 ± 15.6 yr, and the most common presentation was chest pain (38%). Initial echocardiographic left ventricular ejection fraction (EF) was 42.5% ± 9.3%, and the wall motion score index (WMSI) was 1.9 ± 0.3. Six patients (16%) expired during the follow-up period of hospitalization. Based on the analysis of characteristics and clinical factors, the only predictable variable in prognosis was APACHE II score. The patients with APACHE II score greater than 20 had tendency to expire than the others (P = 0.001). Based on present study, APACHE II score more than 20, rather than cardiac function, is associated with mortality in patients with SIC.

  19. APACHE II scoring system on a general intensive care unit: audit of daily APACHE II scores and 6-month survival of 691 patients admitted to a general intensive care unit between May 1990 and December 1991.

    PubMed

    Campbell, N N; Tooley, M A; Willatts, S M

    1994-02-01

    In this paper we present a detailed analysis of the use of the APACHE II (acute physiological and chronic health evaluation) scoring system on all of the patients admitted to the general intensive care unit at the Bristol Royal Infirmary over a 20-month period. The 6-month survival of 691 adult medical and surgical patients following intensive care was recorded and this data was analysed with admission and daily APACHE II scores using a relational database. Our data confirms the relationship between admission APACHE II scores and outcome, with mean scores decreasing as duration of survival increases. We also demonstrate that the best day one scores are approximately 50% less than the admission score, irrespective of outcome, indicating the benefit of intensive care. By contrast, however, the scores on day one have either not improved or have worsened since admission, reflecting the importance of the pre-morbid health status of the patient in determining outcome from intensive care.

  20. APACHE II scoring system on a general intensive care unit: audit of daily APACHE II scores and 6-month survival of 691 patients admitted to a general intensive care unit between May 1990 and December 1991.

    PubMed Central

    Campbell, N N; Tooley, M A; Willatts, S M

    1994-01-01

    In this paper we present a detailed analysis of the use of the APACHE II (acute physiological and chronic health evaluation) scoring system on all of the patients admitted to the general intensive care unit at the Bristol Royal Infirmary over a 20-month period. The 6-month survival of 691 adult medical and surgical patients following intensive care was recorded and this data was analysed with admission and daily APACHE II scores using a relational database. Our data confirms the relationship between admission APACHE II scores and outcome, with mean scores decreasing as duration of survival increases. We also demonstrate that the best day one scores are approximately 50% less than the admission score, irrespective of outcome, indicating the benefit of intensive care. By contrast, however, the scores on day one have either not improved or have worsened since admission, reflecting the importance of the pre-morbid health status of the patient in determining outcome from intensive care. PMID:8196033

  1. APACHE II scoring system on a general intensive care unit: audit of daily APACHE II scores and 6-month survival of 691 patients admitted to a general intensive care unit between May 1990 and December 1991.

    PubMed

    Campbell, N N; Tooley, M A; Willatts, S M

    1994-02-01

    In this paper we present a detailed analysis of the use of the APACHE II (acute physiological and chronic health evaluation) scoring system on all of the patients admitted to the general intensive care unit at the Bristol Royal Infirmary over a 20-month period. The 6-month survival of 691 adult medical and surgical patients following intensive care was recorded and this data was analysed with admission and daily APACHE II scores using a relational database. Our data confirms the relationship between admission APACHE II scores and outcome, with mean scores decreasing as duration of survival increases. We also demonstrate that the best day one scores are approximately 50% less than the admission score, irrespective of outcome, indicating the benefit of intensive care. By contrast, however, the scores on day one have either not improved or have worsened since admission, reflecting the importance of the pre-morbid health status of the patient in determining outcome from intensive care. PMID:8196033

  2. Predicting outcome after traumatic brain injury: development of prognostic scores based on the IMPACT and the APACHE II.

    PubMed

    Raj, Rahul; Siironen, Jari; Kivisaari, Riku; Hernesniemi, Juha; Skrifvars, Markus B

    2014-10-15

    Prediction models are important tools for heterogeneity adjustment in clinical trials and for the evaluation of quality of delivered care to patients with traumatic brain injury (TBI). We sought to improve the predictive performance of the IMPACT (International Mission for Prognosis and Analysis of Clinical Trials) prognostic model by combining it with the APACHE II (Acute Physiology and Chronic Health Evaluation II) for 6-month outcome prediction in patients with TBI treated in the intensive care unit. A total of 890 patients with TBI admitted to a large urban level 1 trauma center in 2009-2012 comprised the study population. The IMPACT and the APACHE II scores were combined using binary logistic regression. A randomized, split-sample technique with secondary bootstrapping was used for model development and internal validation. Model performance was assessed by discrimination (by area under the curve [AUC]), calibration, precision, and net reclassification improvement (NRI). Overall 6-month mortality was 22% and unfavorable neurological outcome 47%. The predictive power of the new combined IMPACT-APACHE II models was significantly superior, compared to the original IMPACT models (AUC, 0.81-0.82 vs. 0.84-0.85; p<0.05) for 6-month mortality prediction, but not for unfavorable outcome prediction (AUC, 0.81-0.82 vs. 0.83; p>0.05). However, NRI showed a significant improvement in risk stratification of patients with unfavorable outcome by the IMPACT-APACHE II models, compared to the original models (NRI, 5.4-23.2%; p<0.05). Internal validation using split-sample and resample bootstrap techniques yielded equivalent results, indicating low grade of overestimation. Our findings show that by combining the APACHE II with the IMPACT, improved 6-month outcome predictive performance is achieved. This may be applicable for heterogeneity adjustment in forthcoming TBI studies.

  3. The performance of customised APACHE II and SAPS II in predicting mortality of mixed critically ill patients in a Thai medical intensive care unit.

    PubMed

    Khwannimit, B; Bhurayanontachai, R

    2009-09-01

    The aim of this study was to evaluate and compare the performance of customised Acute Physiology and Chronic Health Evaluation HII (APACHE II) and Simplified Acute Physiology Score HII (SAPS II) in predicting hospital mortality of mixed critically ill Thai patients in a medical intensive care unit. A prospective cohort study was conducted over a four-year period. The subjects were randomly divided into calibration and validation groups. Logistic regression analysis was used for customisation. The performance of the scores was evaluated by the discrimination, calibration and overall fit in the overall group and across subgroups in the validation group. Two thousand and forty consecutive intensive care unit admissions during the study period were split into two groups. Both customised models showed excellent discrimination. The area under the receiver operating characteristic curve of the customised APACHE II was greater than the customised SAPS II (0.925 and 0.892, P < 0.001). Hosmer-Lemeshow goodness-of-fit showed good calibration for the customised APACHE II in overall populations and various subgroups but insufficient calibration for the customised SAPS II. The customised SAPS II showed good calibration in only the younger, postoperative and sepsis patients subgroups. The overall performance of the customised APACHE II was better than the customised SAPS II (Brier score 0.089 and 0.109, respectively). Our results indicate that the customised APACHE II shows better performance than the customised SAPS II in predicting hospital mortality and could be used to predict mortality and quality assessment in our unit or other intensive care units with a similar case mix.

  4. Liver lobe-based magnetic resonance diffusion-weighted imaging using multiple b values in patients with hepatitis B-related liver cirrhosis: association with the liver disease severity according to the Child-Pugh class

    PubMed Central

    Tang, Hong-Jie; Zhou, Li; Zhang, Xiao-Ming; Liu, Jun; Chen, Tian-Wu; Zeng, Nan-Lin; Wang, Dan; Li, Jie; Huang, Yu-Cheng; Tang, Yu-Lian; Hu, Jiani

    2015-01-01

    OBJECTIVE: To determine the associations of liver lobe-based magnetic resonance diffusion-weighted imaging findings using multiple b values with the presence and Child-Pugh class of cirrhosis in patients with hepatitis B. METHODS: Seventy-four cirrhotic patients with hepatitis B and 25 healthy volunteers underwent diffusion-weighted imaging using b values of 0, 500, 800 and 1000 sec/mm2. The apparent diffusion coefficients of individual liver lobes for b(0,500), b(0,800) and b(0,1000) were derived from the signal intensity averaged across images obtained using b values of 0 and 500 sec/mm2, 0 and 800 sec/mm2, or 0 and 1000 sec/mm2, respectively, and were statistically analyzed to evaluate cirrhosis. RESULTS: The apparent diffusion coefficients for b(0,500), b(0,800) and b(0,1000) inversely correlated with the Child-Pugh class in the left lateral liver lobe, the left medial liver lobe, the right liver lobe and the caudate lobe (r=–0.35 to –0.60, all p<0.05), except for the apparent diffusion coefficient for b(0,1000) in the left medial liver lobe (r=–0.17, p>0.05). Among these parameters, the apparent diffusion coefficient for b(0,500) in the left lateral liver lobe best differentiated normal from cirrhotic liver, with an area under the receiver operating characteristic curve of 0.989. The apparent diffusion coefficient for b(0,800) in the right liver lobe best distinguished Child-Pugh class A from B–C and A–B from C, with areas under the receiver operating characteristic curve of 0.732 and 0.747, respectively. CONCLUSION: Liver lobe-based apparent diffusion coefficients for b(0,500) and b(0,800) appear to be associated with the presence and Child-Pugh class of liver cirrhosis. PMID:26222818

  5. Jicarilla Apaches.

    ERIC Educational Resources Information Center

    Van Roekel, Gertrude B.

    Geronimo's surrender in 1886 ended some 200 years' warfare against encroaching white man in that broad area abutting the Rocky Mountains. Thus, the free-roaming period of Apache life, marked by repeated instances of bad faith and broken treaties, was ended and the Jicarilla Apaches were delivered to their reservation in northern New Mexico. The…

  6. Efficacy of the APACHE II score at ICU discharge in predicting post-ICU mortality and ICU readmission in critically ill surgical patients.

    PubMed

    Lee, H; Lim, C W; Hong, H P; Ju, J W; Jeon, Y T; Hwang, J W; Park, H P

    2015-03-01

    In this study, we evaluated the efficacy of the discharge Acute Physiology and Chronic Health Evaluation (APACHE) II score in predicting post-intensive care unit (ICU) mortality and ICU readmission during the same hospitalisation in a surgical ICU. Of 1190 patients who were admitted to the ICU and stayed >48 hours between October 2007 and March 2010, 23 (1.9%) died and 86 (7.2%) were readmitted after initial ICU discharge, with 26 (3.0%) admitted within 48 hours. The area under the receiver operating characteristics curve of the discharge and admission APACHE II scores in predicting in-hospital mortality was 0.631 (95% confidence interval [CI] 0.603 to 0.658) and 0.669 (95% CI 0.642 to 0.696), respectively (P=0.510). The area under the receiver operating characteristics curve of discharge and admission APACHE II scores for predicting all forms of readmission was 0.606 (95% CI 0.578 to 0.634) and 0.574 (95% CI 0.545 to 0.602), respectively (P=0.316). The area under the receiver operating characteristics curve of discharge APACHE II score in predicting early ICU readmissions was, however, higher than that of admission APACHE II score (0.688 [95% CI 0.660 to 0.714] versus 0.505 [95% CI 0.476 to 0.534], P=0.001). The discharge APACHE II score (odds ratio [OR] 1.1, 95% CI 1.01 to 1.22, P=0.024), unplanned ICU readmission (OR 20.0, 95% CI 7.6 to 53.1, P=0.001), eosinopenia at ICU discharge (OR 6.0, 95% CI 1.34 to 26.9, P=0.019), and hospital length-of-stay before ICU admission (OR 1.02, 95% CI 1.01 to 1.03, P=0.021) were significant independent factors in predicting post-ICU mortality. This study suggests that the discharge APACHE II score may be useful in predicting post-ICU mortality and is superior to the admission APACHE II score in predicting early ICU readmission in surgical ICU patients.

  7. Severity and prognosis of acute organophosphorus pesticide poisoning are indicated by C-reactive protein and copeptin levels and APACHE II score

    PubMed Central

    WU, XINKUAN; XIE, WEI; CHENG, YUELEI; GUAN, QINGLONG

    2016-01-01

    The aim of the present study was to investigate the plasma levels of C-reactive protein (CRP) and copeptin, in addition to the acute physiology and chronic health evaluation II (APACHE II) scores, in patients with acute organophosphorus pesticide poisoning (AOPP). A total of 100 patients with AOPP were included and divided into mild, moderate and severe groups according to AOPP diagnosis and classification standards. Blood samples were collected from all patients on days 1, 3 and 7 following AOPP. The concentrations of CRP and copeptin in the plasma were determined using enzyme-linked immunosorbent assay. All AOPP patients underwent APACHE II scoring and the diagnostic value of these scores was analyzed using receiver operating characteristic curves (ROCs). On days 1, 3 and 7 after AOPP, the levels of CRP and copeptin were increased in correlation with the increase in AOPP severity, and were significantly higher compared with the control groups. Furthermore, elevated CRP and copeptin plasma levels were detected in patients with severe AOPP on day 7, whereas these levels were reduced in patients with mild or moderate AOPP. APACHE II scores, blood lactate level, acetylcholine esterase level, twitch disappearance time, reactivating agent dose and inability to raise the head were the high-risk factors that affected the prognosis of AOPP. Patients with plasma CRP and copeptin levels higher than median values had worse prognoses. The areas under curve for ROCs were 0.89, 0.75 and 0.72 for CRP levels, copeptin levels and APACHE II scores, respectively. In addition, the plasma contents of CRP and copeptin are increased according to the severity of AOPP. Therefore, the results of the present study suggest that CRP and copeptin levels and APACHE II scores may be used for the determination of AOPP severity and the prediction of AOPP prognosis. PMID:26997996

  8. Initial dosing regimen of vancomycin to achieve early therapeutic plasma concentration in critically ill patients with MRSA infection based on APACHE II score.

    PubMed

    Imaura, Masaharu; Yokoyama, Haruko; Kohata, Yuji; Kanai, Riichiro; Kohyama, Tomoki; Idemitsu, Wataru; Maki, Yuichi; Igarashi, Takashi; Takahashi, Hiroyuki; Kanno, Hiroshi; Yamada, Yasuhiko

    2016-06-01

    It is essential to assure the efficacy of antimicrobials at the initial phase of therapy. However, increasing the volume of distribution (Vd) of hydrophilic antimicrobials in critically ill patients leads to reduced antimicrobial concentration in plasma and tissue, which may adversely affect the efficacy of that therapy. The aim of the present study was to establish a theoretical methodology for setting an appropriate level for initial vancomycin therapy in individual patients based on Acute Physiology and Chronic Health Evaluation (APACHE) II score. We obtained data from patients who received intravenous vancomycin for a suspected or definitively diagnosed Gram-positive bacterial infection within 72 h after admission to the intensive care unit. The Vd and elimination half-life (t 1/2) of vancomycin values were calculated using the Bayesian method, and we investigated the relationship between them and APACHE II score. There were significant correlations between APACHE II scores and Vd/actual body weight (ABW), as well as t 1/2 (r = 0.58, p < 0.05 and r = 0.74, p < 0.01, respectively). Our results suggested that the Vd and t 1/2 of vancomycin could be estimated using the following regression equations using APACHE II score.[Formula: see text] [Formula: see text]We found that APACHE II score was a useful index for predicting the Vd and t 1/2 of vancomycin, and used that to establish an initial vancomycin dosing regimen comprised of initial dose and administration interval for individual patients.

  9. Geology and ore deposits of the Monument Valley area, Apache and Navajo counties, Arizona: Part II

    USGS Publications Warehouse

    Witkind, I.J.; Thaden, R.E.

    1958-01-01

    In 1951 and 1952, the U.S. Geological Survey conducted a program of uranium investigations and geologic mapping in the Monument Valley area, Apache and Navajo Counties, Ariz. About 700 square miles were mapped on the Navajo Indian Reservation. A resource appraisal of the area was an inherent part of the program, and is detailed in this report. Production of vanadium and uranium is from two areas, the Monument No. 1 mine area in Navajo County, and the Monument No. 2 mine area in Apache County. In the period 1942-53 about 200,300 tons of ore was produced from these two areas. This ore yielded about 1,700,000 pounds of U3O8 and about 6,500,000 pounds of V2O5. The grade ranged from 0.15 percent U3O8 to 0.60 percent U3O8, and from 0.38 percent V2O5 to 3.02 percent V2O5. The vanadium-uranium ratio is about 4:1. The ore deposits are composed principally of the hydrous calcium-uranium vanadate tyuyamunite in basal channel sediments of the Shinarump member off the Chinle formation. Four types of ore bodies are present: (1) rods, (2) tabular ore bodies, (3) corvusite-type ore bodies, and (4) rolls. The reserves of uranium- and vanadium-bearing material are classed as measured, indicated, inferred, and potential. The reserves are further divided into three grade classes for material 1 foot or more thick: (1) 0.10 percent U3O8 and 1.00 percent V2O5 and above; (2) 0.05 percent U3O8 and 0.50 percent V2O5 and less than 0.10 percent U3O8 and 1.00 percent V2O5; and (3) 0.01 percent U3O8 and 0.10 percent V2O5 and less than 0.05 percent U3O8 and 0.05 percent V2O5. Measured reserves as of June 1953, in the Monument Valley area, Arizona, (all in the Monument No. 2 mine) total about 36,000 tons. Indicated reserves in the first grade class amount to about 62,000 tons. In this same grade class inferred reserves total about 3,000,000 tons. In the second grade class indicated and inferred reserves amount to about 2,000,000 tons. Inferred reserves in the third grade class total about 345

  10. Poisoning severity score, APACHE II and GCS: effective clinical indices for estimating severity and predicting outcome of acute organophosphorus and carbamate poisoning.

    PubMed

    Sam, Kishore Gnana; Kondabolu, Krishnakanth; Pati, Dipanwita; Kamath, Asha; Pradeep Kumar, G; Rao, Padma G M

    2009-07-01

    Self-poisoning with organophosphorus (OP) compounds is a major cause of morbidity and mortality across South Asian countries. To develop uniform and effective management guidelines, the severity of acute OP poisoning should be assessed through scientific methods and a clinical database should be maintained. A prospective descriptive survey was carried out to assess the utility of severity scales in predicting the outcome of 71 organophosphate (OP) and carbamate poisoning patients admitted during a one year period at the Kasturba Hospital, Manipal, India. The Glasgow coma scale (GCS) scores, acute physiology and chronic health evaluation II (APACHE II) scores, predicted mortality rate (PMR) and Poisoning severity score (PSS) were estimated within 24h of admission. Significant correlation (P<0.05) between PSS and GCS and APACHE II and PMR scores were observed with the PSS scores predicting mortality significantly (P< or =0.001). A total of 84.5% patients improved after treatment while 8.5% of the patients were discharged with severe morbidity. The mortality rate was 7.0%. Suicidal poisoning was observed to be the major cause (80.2%), while other reasons attributed were occupational (9.1%), accidental (6.6%), homicidal (1.6%) and unknown (2.5%) reasons. This study highlights the application of clinical indices like GCS, APACHE, PMR and severity scores in predicting mortality and may be considered for planning standard treatment guidelines.

  11. APACHE: an evaluation.

    PubMed

    Wheeler, Megan M

    2009-01-01

    A cursory evaluation of the Acute Physiology and Chronic Health Evaluation, commonly known as the APACHE scoring system, validates its relevancy as the most widely used method for assessing severity and prognosis in intensive care unit patients. The APACHE system works and the evolution from APACHE I to APACHE IV reveal that each version has its positives and negatives. It would behoove critical care nurses to know differences and how each could be best utilized.

  12. The value of procalcitonin and the SAPS II and APACHE III scores in the differentiation of infectious and non-infectious fever in the ICU: a prospective, cohort study.

    PubMed

    Jeon, Eun Ju; Jung, Jae Woo; Choi, Jae Chol; Shin, Jong Wook; Park, In Won; Choi, Byoung Whui; Park, Ae Ja; Kim, Jae Yeol

    2010-11-01

    Early and accurate differentiation between infectious and non-infectious fever is vitally important in the intensive care unit (ICU). In the present study, patients admitted to the medical ICU were screened daily from August 2008 to February 2009. Within 24 hr after the development of fever (>38.3℃), serum was collected for the measurement of the procalcitonin (PCT) and high mobility group B 1 levels. Simplified Acute Physiology Score (SAPS) II and Acute Physiology And Chronic Health Evaluation (APACHE) III scores were also analyzed. Sixty-three patients developed fever among 448 consecutive patients (14.1%). Fever was caused by either infectious (84.1%) or non-infectious processes (15.9%). Patients with fever due to infectious causes showed higher values of serum PCT (7.8±10.2 vs 0.5±0.2 ng/mL, P=0.026), SAPS II (12.0±3.8 vs 7.6±2.7, P=0.006), and APACHE III (48±20 vs 28.7±13.3, P=0.039) than those with non-infectious fever. In receiver operating characteristic curve analysis, the area under the curve was 0.726 (95% CI; 0.587-0.865) for PCT, 0.759 (95% CI; 0.597-0.922) for SAPS II, and 0.715 (95% CI; 0.550-0.880) for APACHE III. Serum PCT, SAPS II, and APACHE III are useful in the differentiation between infectious and non-infectious fever in the ICU.

  13. Intensive Care Society's APACHE II study in Britain and Ireland--I: Variations in case mix of adult admissions to general intensive care units and impact on outcome.

    PubMed Central

    Rowan, K M; Kerr, J H; Major, E; McPherson, K; Short, A; Vessey, M P

    1993-01-01

    OBJECTIVES--To describe the extent of variation in the case mix of adult admissions to general intensive care units in Britain and Ireland and investigate the impact of such variation on outcome. DESIGN--Prospective, cohort study of consecutive admissions to intensive care units. SETTING--26 general intensive care units in Britain and Ireland. SUBJECTS--9099 admissions to the intensive care units studied. MAIN OUTCOME MEASURE--Death or survival at discharge before and after adjustment of case mix (age, history of chronic conditions, surgical status, diagnosis, and severity of illness) according to the APACHE II method. RESULTS--Important differences in case mix were found, with large variations between the units. Hospital mortality was significantly associated with most of the case mix factors investigated. CONCLUSIONS--Comparing crude death rates in hospital between intensive care units may be misleading indicators of performance. The collection of data on case mix needs to be standardised and differences in case mix adjusted for when comparing outcome between different intensive care units. PMID:8241908

  14. Apache, Vol. I.

    ERIC Educational Resources Information Center

    Bodiroga, Ronald, Comp.; And Others

    The short stories, poems, and cultural descriptions about American Indians (volume 1 of two) are the result of a combined effort of the 7th grade students of Rice School District (Sacaton, Arizona), their teacher, and the parents and friends of the students of the San Carlos Apache Indian Reservation (Arizona). The 24 student contributors prepared…

  15. SAN CARLOS APACHE PAPERS.

    ERIC Educational Resources Information Center

    ROESSEL, ROBERT A., JR.

    THE FIRST SECTION OF THIS BOOK COVERS THE HISTORICAL AND CULTURAL BACKGROUND OF THE SAN CARLOS APACHE INDIANS, AS WELL AS AN HISTORICAL SKETCH OF THE DEVELOPMENT OF THEIR FORMAL EDUCATIONAL SYSTEM. THE SECOND SECTION IS DEVOTED TO THE PROBLEMS OF TEACHERS OF THE INDIAN CHILDREN IN GLOBE AND SAN CARLOS, ARIZONA. IT IS DIVIDED INTO THREE PARTS--(1)…

  16. Comparison of Ranson, Glasgow, MOSS, SIRS, BISAP, APACHE-II, CTSI Scores, IL-6, CRP, and Procalcitonin in Predicting Severity, Organ Failure, Pancreatic Necrosis, and Mortality in Acute Pancreatitis.

    PubMed

    Khanna, Ajay K; Meher, Susanta; Prakash, Shashi; Tiwary, Satyendra Kumar; Singh, Usha; Srivastava, Arvind; Dixit, V K

    2013-01-01

    Background. Multifactorial scorings, radiological scores, and biochemical markers may help in early prediction of severity, pancreatic necrosis, and mortality in patients with acute pancreatitis (AP). Methods. BISAP, APACHE-II, MOSS, and SIRS scores were calculated using data within 24 hrs of admission, whereas Ranson and Glasgow scores after 48 hrs of admission; CTSI was calculated on day 4 whereas IL-6 and CRP values at end of study. Predictive accuracy of scoring systems, sensitivity, specificity, and positive and negative predictive values of various markers in prediction of severe acute pancreatitis, organ failure, pancreatic necrosis, admission to intensive care units and mortality were calculated. Results. Of 72 patients, 31 patients had organ failure and local complication classified as severe acute pancreatitis, 17 had pancreatic necrosis, and 9 died (12.5%). Area under curves for Ranson, Glasgow, MOSS, SIRS, APACHE-II, BISAP, CTSI, IL-6, and CRP in predicting SAP were 0.85, 0.75, 0.73, 0.73, 0.88, 0.80, 0.90, and 0.91, respectively, for pancreatic necrosis 0.70, 0.64, 0.61, 0.61, 0.68, 0.61, 0.75, 0.86, and 0.90, respectively, and for mortality 0.84, 0.83, 0.77, 0.76, 0.86, 0.83, 0.57, 0.80, and 0.75, respectively. Conclusion. CRP and IL-6 have shown a promising result in early detection of severity and pancreatic necrosis whereas APACHE-II and Ranson score in predicting AP related mortality in this study.

  17. HVI and HVII mitochondrial DNA data in Apaches and Navajos.

    PubMed

    Budowle, Bruce; Allard, Marc W; Fisher, Constance L; Isenberg, Alice R; Monson, Keith L; Stewart, John E B; Wilson, Mark R; Miller, Kevin W P

    2002-08-01

    Most mtDNA studies on Native Americans have concentrated on hypervariable region I (HVI) sequence data. Mitochondrial DNA haplotype data from hypervariable regions I and II (HVI and HVII) have been compiled from Apaches (N=180) and Navajos (N=146). The inclusion of HVII data increases the amount of information that can be obtained from low diversity population groups. Less mtDNA variation was observed in the Apaches and Navajos than in major population groups. The majority of the mtDNA sequences were observed more than once; only 17.8% (32/180) of the Apache sequences and 25.8% of the Navajo sequences were observed once. Most of the haplotypes in Apaches and Navajos fall into the A and B haplogroups. Although a limited number of haplogroups were observed, both sample populations exhibit sufficient variation for forensic mtDNA typing. Genetic diversity was 0.930 in the Apache sample and 0.963 in the Navajo sample. The random match probability was 7.48% in the Apache sample and 4.40% in the Navajo sample. The average number of nucleotide differences between individuals in a database is 9.0 in the Navajo sample and 7.7 in the Apache sample. The data demonstrate that mtDNA sequencing can be informative in forensic cases where Native American population data are used. PMID:12185491

  18. The Jicarilla Apaches. A Study in Survival.

    ERIC Educational Resources Information Center

    Gunnerson, Dolores A.

    Focusing on the ultimate fate of the Cuartelejo and/or Paloma Apaches known in archaeological terms as the Dismal River people of the Central Plains, this book is divided into 2 parts. The early Apache (1525-1700) and the Jicarilla Apache (1700-1800) tribes are studied in terms of their: persistent cultural survival, social/political adaptability,…

  19. Curriculum Program for the Apache Language.

    ERIC Educational Resources Information Center

    Whiteriver Public Schools, AZ.

    These curriculum materials from the Whiteriver (Arizona) Elementary School consist of--(1) an English-Apache word list of some of the most commonly used words in Apache, 29p.; (2) a list of enclitics with approximate or suggested meanings and illustrations of usage, 5 p.; (3) an illustrated chart of Apache vowels and consonants, various written…

  20. Prognostic scoring systems for mortality in intensive care units--the APACHE model.

    PubMed

    Niewiński, Grzegorz; Starczewska, Małgorzata; Kański, Andrzej

    2014-01-01

    The APACHE (Acute Physiology and Chronic Health Evaluation) scoring system is time consuming. The mean time for introducing a patient's data to APACHE IV is 37.3 min. Nevertheless, statisticians have known for years that the higher the number of variables the mathematical model describes, the more accurate the model. Because of the necessity of gathering data over a 24-hour period and of determining one cause for ICU admission, the system is troublesome and prone to mistakes. The evolution of the APACHE scoring system is an example of unfulfilled hopes for accurately estimating the risk of death for patients admitted to the ICU; satisfactory prognostic effects resulting from the use of APACHE II and III have been recently studied in patients undergoing liver transplantations. Because no increase in the predictive properties of successive versions has been observed, the search for other solutions continues. The APACHE IV scoring system is helpful; however, its use without prepared spreadsheets is almost impractical. Therefore, although many years have passed since its original publication, APACHE II or its extension APACHE III is currently used in clinical practice.

  1. Escape from Albuquerque: An Apache Memorate.

    ERIC Educational Resources Information Center

    Greenfeld, Philip J.

    2001-01-01

    Clarence Hawkins, a White Mountain Apache, escaped from the Albuquerque Indian School around 1920. His 300-mile trip home, made with two other boys, exemplifies the reaction of many Indian youths to the American government's plans for cultural assimilation. The tale is told in the form of traditional Apache narrative. (TD)

  2. KinderApache Song and Dance Project.

    ERIC Educational Resources Information Center

    Shanklin, M. Trevor; Paciotto, Carla; Prater, Greg

    This paper describes activities and evaluation of the KinderApache Song and Dance Project, piloted in a kindergarten class in Cedar Creek (Arizona) on the White Mountain Apache Reservation. Introducing Native-language song and dance in kindergarten could help foster a sense of community and cultural pride and greater awareness of traditional…

  3. A comparison of Simplified Acute Physiology Score II, Acute Physiology and Chronic Health Evaluation II and Acute Physiology and Chronic Health Evaluation III scoring system in predicting mortality and length of stay at surgical intensive care unit

    PubMed Central

    Gilani, Mahryar Taghavi; Razavi, Majid; Azad, Azadeh Mokhtari

    2014-01-01

    Background: In critically ill patients, several scoring systems have been developed over the last three decades. The Acute Physiology and Chronic Health Evaluation (APACHE) and the Simplified Acute Physiology Score (SAPS) are the most widely used scoring systems in the intensive care unit (ICU). The aim of this study was to assess the prognostic accuracy of SAPS II and APACHE II and APACHE III scoring systems in predicting short-term hospital mortality of surgical ICU patients. Materials and Methods: Prospectively collected data from 202 patients admitted to Mashhad University Hospital postoperative ICU were analyzed. Calibration was estimated using the Hosmer-Lemeshow goodness-of-fit test. Discrimination was evaluated by using the receiver operating characteristic (ROC) curves and area under a ROC curve (AUC). Result: Two hundred and two patients admitted on post-surgical ICU were evaluated. The mean SAPS II, APACHE II, and APACHE III scores for survivors were found to be significantly lower than of non-survivors. The calibration was best for APACHE II score. Discrimination was excellent for APACHE II (AUC: 0.828) score and acceptable for APACHE III (AUC: 0.782) and SAPS II (AUC: 0.778) scores. Conclusion: APACHE II provided better discrimination than APACHE III and SAPS II calibration was good at APACHE II and poor at APACHE III and SAPS II. Use of APACHE II was excellent in this post-surgical ICU. PMID:24791049

  4. The Apache OODT Project: An Introduction

    NASA Astrophysics Data System (ADS)

    Mattmann, C. A.; Crichton, D. J.; Hughes, J. S.; Ramirez, P.; Goodale, C. E.; Hart, A. F.

    2012-12-01

    Apache OODT is a science data system framework, borne over the past decade, with 100s of FTEs of investment, tens of sponsoring agencies (NASA, NIH/NCI, DoD, NSF, universities, etc.), and hundreds of projects and science missions that it powers everyday to their success. At its core, Apache OODT carries with it two fundamental classes of software services and components: those that deal with information integration from existing science data repositories and archives, that themselves have already-in-use business processes and models for populating those archives. Information integration allows search, retrieval, and dissemination across these heterogeneous systems, and ultimately rapid, interactive data access, and retrieval. The other suite of services and components within Apache OODT handle population and processing of those data repositories and archives. Workflows, resource management, crawling, remote data retrieval, curation and ingestion, along with science data algorithm integration all are part of these Apache OODT software elements. In this talk, I will provide an overview of the use of Apache OODT to unlock and populate information from science data repositories and archives. We'll cover the basics, along with some advanced use cases and success stories.

  5. Optimizing CMS build infrastructure via Apache Mesos

    NASA Astrophysics Data System (ADS)

    Abdurachmanov, David; Degano, Alessandro; Elmer, Peter; Eulisse, Giulio; Mendez, David; Muzaffar, Shahzad

    2015-12-01

    The Offline Software of the CMS Experiment at the Large Hadron Collider (LHC) at CERN consists of 6M lines of in-house code, developed over a decade by nearly 1000 physicists, as well as a comparable amount of general use open-source code. A critical ingredient to the success of the construction and early operation of the WLCG was the convergence, around the year 2000, on the use of a homogeneous environment of commodity x86-64 processors and Linux. Apache Mesos is a cluster manager that provides efficient resource isolation and sharing across distributed applications, or frameworks. It can run Hadoop, Jenkins, Spark, Aurora, and other applications on a dynamically shared pool of nodes. We present how we migrated our continuous integration system to schedule jobs on a relatively small Apache Mesos enabled cluster and how this resulted in better resource usage, higher peak performance and lower latency thanks to the dynamic scheduling capabilities of Mesos.

  6. Wisdom Sits in Places: Landscape and Language among the Western Apache.

    ERIC Educational Resources Information Center

    Basso, Keith H.

    This book of essays draws on a cultural geography project in which an ethnographer and Apache consultants mapped the area around Cibecue, on the Fort Apache Reservation (Arizona). The essays focus on different Apache individuals and examine the ways that Apache constructions of place reach deeply into other cultural spheres. Many Apache place…

  7. Apache Open Climate Workbench: Building Open Source Climate Science Tools and Community at the Apache Software Foundation

    NASA Astrophysics Data System (ADS)

    Joyce, M.; Ramirez, P.; Boustani, M.; Mattmann, C. A.; Khudikyan, S.; McGibbney, L. J.; Whitehall, K. D.

    2014-12-01

    Apache Open Climate Workbench (OCW; https://climate.apache.org/) is a Top-Level Project at the Apache Software Foundation that aims to provide a suite of tools for performing climate science evaluations using model outputs from a multitude of different sources (ESGF, CORDEX, U.S. NCA, NARCCAP) with remote sensing data from NASA, NOAA, and other agencies. Apache OCW is the second NASA project to become a Top-Level Project at the Apache Software Foundation. It grew out of the Jet Propulsion Laboratory's (JPL) Regional Climate Model Evaluation System (RCMES) project, a collaboration between JPL and the University of California, Los Angeles' Joint Institute for Regional Earth System Science and Engineering (JIFRESSE). Apache OCW provides scientists and developers with tools for data manipulation, metrics for dataset comparisons, and a visualization suite. In addition to a powerful low-level API, Apache OCW also supports a web application for quick, browser-controlled evaluations, a command line application for local evaluations, and a virtual machine for isolated experimentation with minimal setup. This talk will look at the difficulties and successes of moving a closed community research project out into the wild world of open source. We'll explore the growing pains Apache OCW went through to become a Top-Level Project at the Apache Software Foundation as well as the benefits gained by opening up development to the broader climate and computer science communities.

  8. A Phase II Study of Cixutumumab (IMC-A12, NSC742460) in Advanced Hepatocellular Carcinoma

    PubMed Central

    Abou-Alfa, Ghassan K.; Capanu, Marinela; O’Reilly, Eileen M.; Ma, Jennifer; Chou, Joanne F.; Gansukh, Bolorsukh; Shia, Jinru; Kalin, Marcia; Katz, Seth; Abad, Leslie; Reidy-Lagunes, Diane L.; Kelsen, David P.; Chen, Helen X.; Saltz, Leonard B.

    2014-01-01

    Background and Aims IGF-IR is implicated in hepatic carcinogenesis. This and preliminary evidence of biological activity of anti-IGF-1R monoclonal antibody cixutumumab in phase I trials prompted this phase II study. Methods Patients with advanced HCC, Child-Pugh A-B8, received cixutumumab 6 mg/kg weekly, in a Simon two-stage design study, with the primary endpoints being 4-month PFS and RECIST-defined response rate. Tissue and circulating markers plus different HCC scoring systems were evaluated for correlation with PFS and OS. Results As a result of pre-specified futility criteria, only stage 1 was accrued: N= 24: median age 67.5 years (range 49–83), KPS 80% (70–90%), 20 males (83%), 9 stage III (37%)/15 stage IV (63%), 18 Child-Pugh A (75%), 11 HBV (46%) /10 HCV (42%)/11 alcoholic cirrhosis (46%)/2 NASH (8%), 11 (46%) diabetic. Median number of doses: 7 (range 1–140). Grade 3/4 toxicities > 10% included: diabetes, elevated liver function tests, hyponatremia, and lymphopenia. Four-month PFS was 30% (95% CI 13–48), and there were no objective responses. Median overall survival was 8 months (95%CI 5.8– 14). IGF-R1 staining did not correlate with outcome. Elevated IGFBP-1 correlated with improved PFS (1.2 [95%CI 1–1.4]; p 0.009) and OS (1.2 [95%CI 1.1–1.4]; p 0.003). Conclusions Cixutumumab monotherapy did not have clinically meaningful activity in this unselected HCC population. Grade 3–4 hyperglycemia occurred in 46% of patients. Elevated IGFBP-1 correlated with improved PFS and OS. PMID:24045151

  9. Grades 1-8, Apache Junction Unified School District 43, Apache Junction, Arizona. PLATO Evaluation Series.

    ERIC Educational Resources Information Center

    Quinn, David W.; Quinn, Nancy W.

    Apache Junction Unified School District, Arizona, has embarked on a 5-year program of instructional improvement using technology. PLATO Elementary reading and mathematics products were installed in the district's elementary and middle schools at the beginning of the 1999-2000 school year. This evaluation studied the use and preliminary student…

  10. 40 CFR 52.150 - Yavapai-Apache Reservation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the Clean Air Act and the provisions of 40 CFR 52.21(g), the Yavapai-Apache Indian Reservation is...) The provisions for prevention of significant deterioration of air quality at 40 CFR 52.21 are... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Yavapai-Apache Reservation....

  11. Go-Gii-Ya [A Jicarilla Apache Religious Celebration].

    ERIC Educational Resources Information Center

    Pesata, Levi; And Others

    Developed by utilizing only Jicarilla Apache people as resources to preserve the authenticity of the material and information, this booklet presents information on the Jicarilla Apache celebration of "Go-gii-ya". "Go-gii-ya" is a religious feast and ceremony held annually over a three-day period which climaxes on the fifteenth day of September.…

  12. 40 CFR 52.150 - Yavapai-Apache Reservation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.150 Yavapai-Apache Reservation. (a) The provisions for prevention of significant deterioration of air quality at 40 CFR 52.21 are... the Clean Air Act and the provisions of 40 CFR 52.21(g), the Yavapai-Apache Indian Reservation...

  13. 40 CFR 52.150 - Yavapai-Apache Reservation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.150 Yavapai-Apache Reservation. (a) The provisions for prevention of significant deterioration of air quality at 40 CFR 52.21 are... the Clean Air Act and the provisions of 40 CFR 52.21(g), the Yavapai-Apache Indian Reservation...

  14. 40 CFR 52.150 - Yavapai-Apache Reservation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.150 Yavapai-Apache Reservation. (a) The provisions for prevention of significant deterioration of air quality at 40 CFR 52.21 are... the Clean Air Act and the provisions of 40 CFR 52.21(g), the Yavapai-Apache Indian Reservation...

  15. 40 CFR 52.150 - Yavapai-Apache Reservation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.150 Yavapai-Apache Reservation. (a) The provisions for prevention of significant deterioration of air quality at 40 CFR 52.21 are... the Clean Air Act and the provisions of 40 CFR 52.21(g), the Yavapai-Apache Indian Reservation...

  16. San Carlos Apache Tribe - Energy Organizational Analysis

    SciTech Connect

    Rapp, James; Albert, Steve

    2012-04-01

    The San Carlos Apache Tribe (SCAT) was awarded $164,000 in late-2011 by the U.S. Department of Energy (U.S. DOE) Tribal Energy Program's "First Steps Toward Developing Renewable Energy and Energy Efficiency on Tribal Lands" Grant Program. This grant funded:  The analysis and selection of preferred form(s) of tribal energy organization (this Energy Organization Analysis, hereinafter referred to as "EOA").  Start-up staffing and other costs associated with the Phase 1 SCAT energy organization.  An intern program.  Staff training.  Tribal outreach and workshops regarding the new organization and SCAT energy programs and projects, including two annual tribal energy summits (2011 and 2012). This report documents the analysis and selection of preferred form(s) of a tribal energy organization.

  17. 76 FR 72969 - Proclaiming Certain Lands as Reservation for the Fort Sill Apache Indian Tribe

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... Bureau of Indian Affairs Proclaiming Certain Lands as Reservation for the Fort Sill Apache Indian Tribe... acres, more or less, as the Fort Sill Apache Indian Reservation for the Fort Sill Apache Tribe of... Apache Indian Reservation for the exclusive use of Indians entitled by enrollment or by tribal...

  18. Formal Education and Culture Change, A Modern Apache Indian Community and Government Education Programs.

    ERIC Educational Resources Information Center

    Parmee, Edward A.

    The study critically examines conditions on the San Carlos Apache Reservation that have resulted from outside manipulation done without regard for the traditional heritage of the Apaches or without provision of training for the Apaches in understanding and facilitating change. The effects of educational experiences available to the Apaches are…

  19. Comparison of acute physiology and chronic health evaluation II and acute physiology and chronic health evaluation IV to predict intensive care unit mortality

    PubMed Central

    Parajuli, Bashu Dev; Shrestha, Gentle S.; Pradhan, Bishwas; Amatya, Roshana

    2015-01-01

    Context: Clinical assessment of severity of illness is an essential component of medical practice to predict the outcome of critically ill-patient. Acute Physiology and Chronic Health Evaluation (APACHE) model is one of the widely used scoring systems. Aims: This study was designed to evaluate the Performance of APACHE II and IV scoring systems in our Intensive Care Unit (ICU). Settings and Design: A prospective study in 6 bedded ICU, including 76 patients all above 15 years. Subjects and Methods: APACHE II and APACHE IV scores were calculated based on the worst values in the first 24 h of admission. All enrolled patients were followed, and outcome was recorded as survivors or nonsurvivors. Statistical Analysis Used: SPSS version 17. Results: The mean APACHE score was significantly higher among nonsurvivors than survivors (P < 0.005). Discrimination for APACHE II and APACHE IV was fair with area under receiver operating characteristic curve of 0.73 and 0.79 respectively. The cut-off point with best Youden index for APACHE II was 17 and for APACHE IV was 85. Above cut-off point, mortality was higher for both models (P < 0.005). Hosmer–Lemeshow Chi-square coefficient test showed better calibration for APACHE II than APACHE IV. A positive correlation was seen between the models with Spearman's correlation coefficient of 0.748 (P < 0.01). Conclusions: Discrimination was better for APACHE IV than APACHE II model however Calibration was better for APACHE II than APACHE IV model in our study. There was good correlation between the two models observed in our study. PMID:25722550

  20. APACHE score, Severity Index of Paraquat Poisoning, and serum lactic acid concentration in the prognosis of paraquat poisoning of Chinese Patients.

    PubMed

    Xu, Shuyun; Hu, Hai; Jiang, Zhen; Tang, Shiyuan; Zhou, Yuangao; Sheng, Jie; Chen, Jinggang; Cao, Yu

    2015-02-01

    Many prognostic indictors have been studied to evaluate the prognosis of paraquat poisoning. However, the optimal indicator remains unclear. To determine the value of the Acute Physiology and Chronic Health Evaluation II (APACHE II) score, the Severity Index of Paraquat Poisoning (SIPP), and serum lactate levels in the prognosis of paraquat poisoning, we performed a prospective study that enrolled 143 paraquat patients. Data were collected from patients (161) at West China Hospital in Chengdu, China, including details about the patients' general conditions, laboratory examinations, and treatment. Receiver operating characteristic curves for predicting inpatient mortality based on APACHE II score, SIPP, and lactate levels were generated. To analyze the best cutoff values for lactate levels, APACHE II scores, and SIPP in predicting the prognosis of paraquat poisoning, the initial parameters on admission and 7-day survival curves of patients with lactate levels greater than or equal to 2.95 mmol/L, APACHE II score greater than or equal to 15.22, and SIPP greater than or equal to 5.50 h · mg/L at the time of arrival at West China Hospital were compared using the 1-way analysis of variance and the log-rank test. The APACHE II score (5.45 [3.67] vs 11.29 [4.31]), SIPP (2.78 [1.89] vs 7.63 [2.46] h · mg/L), and lactate level (2.78 [1.89] vs 7.63 [2.46] mmol/L) were significantly lower in survivors (77) after oral ingestion of paraquat, compared with nonsurvivors (66). The APACHE II score, SIPP, and lactate level had different areas under the curve (0.847, 0.789, and 0.916, respectively) and accuracy (0.64, 0.84, and 0.89, respectively). Respiratory rate, serum creatinine level, Paco2, and mortality rate at 7 days after admission in patients with lactate levels greater than or equal to 2.95 mmol/L were markedly different compared with those of other patients (P < 0.05). The predictive value of lactic acid was superior to that of APACHE II score and SIPP for acute oral

  1. Mescalero Apache Tribe Monitored Retrievable Storage (MRS)

    SciTech Connect

    Peso, F.

    1992-03-13

    The Nuclear Waste Policy Act of 1982, as amended, authorizes the siting, construction and operation of a Monitored Retrievable Storage (MRS) facility. The MRS is intended to be used for the temporary storage of spent nuclear fuel from the nation's nuclear power plants beginning as early as 1998. Pursuant to the Nuclear Waste Policy Act, the Office of the Nuclear Waste Negotiator was created. On October 7, 1991, the Nuclear Waste Negotiator invited the governors of states and the Presidents of Indian tribes to apply for government grants in order to conduct a study to assess under what conditions, if any, they might consider hosting an MRS facility. Pursuant to this invitation, on October 11, 1991 the Mescalero Apache Indian Tribe of Mescalero, NM applied for a grant to conduct a phased, preliminary study of the safety, technical, political, environmental, social and economic feasibility of hosting an MRS. The preliminary study included: (1) An investigative education process to facilitate the Tribe's comprehensive understanding of the safety, environmental, technical, social, political, and economic aspects of hosting an MRS, and; (2) The development of an extensive program that is enabling the Tribe, in collaboration with the Negotiator, to reach an informed and carefully researched decision regarding the conditions, (if any), under which further pursuit of the MRS would be considered. The Phase 1 grant application enabled the Tribe to begin the initial activities necessary to determine whether further consideration is warranted for hosting the MRS facility. The Tribe intends to pursue continued study of the MRS in order to meet the following objectives: (1) Continuing the education process towards a comprehensive understanding of the safety, environmental, technical, social and economic aspects of the MRS; (2) Conducting an effective public participation and information program; (3) Participating in MRS meetings.

  2. San Carlos Apache Indian Reservation and Bylas, Arizona; Fort Thomas Public Schools. National Study of American Indian Education, Series 1, No. 18, Final Report.

    ERIC Educational Resources Information Center

    Chilcott, John H.; Anderson, Ned

    As part of the Final Report of the National Study of American Indian Education, Part I of this document depicts the demographic, socioeconomic, educational, and social aspects of the San Carlos Apache Indian Reservation and community of Bylas. Part II places specific emphasis on recent history, economy, problems and new programs, and the…

  3. Evidence of sexually dimorphic introgression in Pinaleno Mountain Apache trout

    USGS Publications Warehouse

    Porath, M.T.; Nielsen, J.L.

    2003-01-01

    The high-elevation headwater streams of the Pinaleno Mountains support small populations of threatened Apache trout Oncorhynchus apache that were stocked following the chemical removal of nonnative salmonids in the 1960s. A fisheries survey to assess population composition, growth, and size structure confirmed angler reports of infrequent occurrences of Oncorhynchus spp. exhibiting the external morphological characteristics of both Apache trout and rainbow trout O. mykiss. Nonlethal tissue samples were collected from 50 individuals in the headwaters of each stream. Mitochondrial DNA (mtDNA) sequencing and amplification of nuclear microsatellite loci were used to determine the levels of genetic introgression by rainbow trout in Apache trout populations at these locations. Sexually dimorphic introgression from the spawning of male rainbow trout with female Apache trout was detected using mtDNA and microsatellites. Estimates of the degree of hybridization based on three microsatellite loci were 10-88%. The use of nonlethal DNA genetic analyses can supplement information obtained from standard survey methods and be useful in assessing the relative importance of small and sensitive populations with a history of nonnative introductions.

  4. 76 FR 74783 - Apache Hydro LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-01

    ... Energy Regulatory Commission Apache Hydro LLC; Notice of Preliminary Permit Application Accepted for..., Apache Hydro LLC filed an application for a preliminary permit, pursuant to section 4(f) of the Federal... Wash, Apache Canyon, in Hudspeth, Culberson, and Reeves Counties, Texas. The sole purpose of...

  5. Western Apache Oral Histories and Traditions of the Camp Grant Massacre

    ERIC Educational Resources Information Center

    Colwell-Chanthaphonh, Chip

    2003-01-01

    The Camp Grant Massacre remains a salient moment for contemporary Western Apache peoples. Although a difficult part of their history, it continues to instruct Apaches and non-Apaches about the sacrifices of those who have gone before and the circumstances that have shaped the modern world. The story of the massacre was first preserved by personal…

  6. Study on the Fort Apache: Perceptions of an Educational Environment.

    ERIC Educational Resources Information Center

    Hutchison, Jerry E.

    1979-01-01

    Teachers, parents, and students on the White Mountain Apache reservation perceive school activities quite differently, indicating parental isolation and a lack of communication among the groups. Although students tend to agree with teachers more than with parents, teachers alone feel students are inadequately prepared for postsecondary school…

  7. Interrupting White Mountain Apache Language Shift: An Insider's View.

    ERIC Educational Resources Information Center

    Adley-SantaMaria, Bernadette

    1999-01-01

    A White Mountain Apache (WMA) doctoral student collaborating with a non-Indian linguist on a grammar book project discusses the status of the WMA language; causes of WMA language shift; aspects of insider-outsider collaboration; implications for revitalization and maintenance of indigenous languages; and the responsibilities of individuals,…

  8. An Exploratory Study of Apache Middle School Students' Computer Animation.

    ERIC Educational Resources Information Center

    Stokrocki, Mary; Buckpitt, Marcia

    The paper describes a participant observation study of a 3 week summer art program for Apache middle school students on the White Mountain Reservation. Computer art skills, specifically animation using a menu-driven computer paint program, were the focus of the investigation. Because it was in the context of a summer program, instruction was…

  9. Nutrition Survey of White Mountain Apache Preschool Children.

    ERIC Educational Resources Information Center

    Owen, George M.; And Others

    As part of a national study of the nutrition of preschool children, data were collected on 201 Apache children, 1 to 6 years of age, living on an Indian reservation in Arizona. This report reviews procedures and clinical findings, and gives an analysis of growth data including skeletal maturation, nutrient intakes and clinical biochemical data. In…

  10. Issues in Language Textbook Development: The Case of Western Apache.

    ERIC Educational Resources Information Center

    de Reuse, Willem J.

    Two experimental language-learning textbooks were developed in collaboration with Apache-speaking scholars from the San Carlos and White Mountain Reservations. One was written in the grammar-translation tradition and modeled after successful textbooks for Navajo and Papago. While the text's main purpose is to teach elementary conversational…

  11. The White Mountain Apache Child Protection Service Training Curriculum. Nohwii Chaghashe Baa da gontzaa (Protect Our Apache Children).

    ERIC Educational Resources Information Center

    Gonzalez-Santin, Edwin, Comp.

    This curriculum manual provides 8 days of training for child protective services (CPS) personnel (social workers and administrators) working in the White Mountain Apache tribal community. Each of the first seven units in the manual contains a brief description of contents, course objectives, time required, key concepts, possible discussion topics,…

  12. From Child-Pugh to Model for End-Stage Liver Disease: Deciding Who Needs a Liver Transplant.

    PubMed

    Reddy, Sheela S; Civan, Jesse M

    2016-05-01

    This article reviews the historical evolution of the liver transplant organ allocation policy and the indications/contraindications for liver transplant, and provides an overview of the liver transplant evaluation process. The article is intended to help internists determine whether and when referral to a liver transplant center is indicated, and to help internists to counsel patients whose initial evaluation at a transplant center is pending. PMID:27095638

  13. Project Apache: A Reservation, Community-Based Early Intervention Program for Apache Infants and Toddlers with Special Needs and Their Families.

    ERIC Educational Resources Information Center

    O'Connell, Joanne C.

    This final report describes the outcomes of Project Apache, a reservation, community-based early intervention program designed to develop comprehensive services to Apache infants and toddlers who are at risk of developing a disability and their families. The project uses a home-based service delivery program with paraprofessional aides to assist…

  14. Apache Drill: Interactive Ad-Hoc Analysis at Scale.

    PubMed

    Hausenblas, Michael; Nadeau, Jacques

    2013-06-01

    Apache Drill is a distributed system for interactive ad-hoc analysis of large-scale datasets. Designed to handle up to petabytes of data spread across thousands of servers, the goal of Drill is to respond to ad-hoc queries in a low-latency manner. In this article, we introduce Drill's architecture, discuss its extensibility points, and put it into the context of the emerging offerings in the interactive analytics realm.

  15. Solar Feasibility Study May 2013 - San Carlos Apache Tribe

    SciTech Connect

    Rapp, Jim; Duncan, Ken; Albert, Steve

    2013-05-01

    The San Carlos Apache Tribe (Tribe) in the interests of strengthening tribal sovereignty, becoming more energy self-sufficient, and providing improved services and economic opportunities to tribal members and San Carlos Apache Reservation (Reservation) residents and businesses, has explored a variety of options for renewable energy development. The development of renewable energy technologies and generation is consistent with the Tribe’s 2011 Strategic Plan. This Study assessed the possibilities for both commercial-scale and community-scale solar development within the southwestern portions of the Reservation around the communities of San Carlos, Peridot, and Cutter, and in the southeastern Reservation around the community of Bylas. Based on the lack of any commercial-scale electric power transmission between the Reservation and the regional transmission grid, Phase 2 of this Study greatly expanded consideration of community-scale options. Three smaller sites (Point of Pines, Dudleyville/Winkleman, and Seneca Lake) were also evaluated for community-scale solar potential. Three building complexes were identified within the Reservation where the development of site-specific facility-scale solar power would be the most beneficial and cost-effective: Apache Gold Casino/Resort, Tribal College/Skill Center, and the Dudleyville (Winkleman) Casino.

  16. Satellite Imagery Production and Processing Using Apache Hadoop

    NASA Astrophysics Data System (ADS)

    Hill, D. V.; Werpy, J.

    2011-12-01

    The United States Geological Survey's (USGS) Earth Resources Observation and Science (EROS) Center Land Science Research and Development (LSRD) project has devised a method to fulfill its processing needs for Essential Climate Variable (ECV) production from the Landsat archive using Apache Hadoop. Apache Hadoop is the distributed processing technology at the heart of many large-scale, processing solutions implemented at well-known companies such as Yahoo, Amazon, and Facebook. It is a proven framework and can be used to process petabytes of data on thousands of processors concurrently. It is a natural fit for producing satellite imagery and requires only a few simple modifications to serve the needs of science data processing. This presentation provides an invaluable learning opportunity and should be heard by anyone doing large scale image processing today. The session will cover a description of the problem space, evaluation of alternatives, feature set overview, configuration of Hadoop for satellite image processing, real-world performance results, tuning recommendations and finally challenges and ongoing activities. It will also present how the LSRD project built a 102 core processing cluster with no financial hardware investment and achieved ten times the initial daily throughput requirements with a full time staff of only one engineer. Satellite Imagery Production and Processing Using Apache Hadoop is presented by David V. Hill, Principal Software Architect for USGS LSRD.

  17. Vegetative response to water availability on the San Carlos Apache Reservation

    USGS Publications Warehouse

    Petrakis, Roy; Wu, Zhuoting; McVay, Jason; Middleton, Barry R.; Dye, Dennis G.; Vogel, John M.

    2016-01-01

    On the San Carlos Apache Reservation in east-central Arizona, U.S.A., vegetation types such as ponderosa pine forests, pinyon-juniper woodlands, and grasslands have significant ecological, cultural, and economic value for the Tribe. This value extends beyond the tribal lands and across the Western United States. Vegetation across the Southwestern United States is susceptible to drought conditions and fluctuating water availability. Remotely sensed vegetation indices can be used to measure and monitor spatial and temporal vegetative response to fluctuating water availability conditions. We used the Moderate Resolution Imaging Spectroradiometer (MODIS)-derived Modified Soil Adjusted Vegetation Index II (MSAVI2) to measure the condition of three dominant vegetation types (ponderosa pine forest, woodland, and grassland) in response to two fluctuating environmental variables: precipitation and the Standardized Precipitation Evapotranspiration Index (SPEI). The study period covered 2002 through 2014 and focused on a region within the San Carlos Apache Reservation. We determined that grassland and woodland had a similar moderate to strong, year-round, positive relationship with precipitation as well as with summer SPEI. This suggests that these vegetation types respond negatively to drought conditions and are more susceptible to initial precipitation deficits. Ponderosa pine forest had a comparatively weaker relationship with monthly precipitation and summer SPEI, indicating that it is more buffered against short-term drought conditions. This research highlights the response of multiple, dominant vegetation types to seasonal and inter-annual water availability. This research demonstrates that multi-temporal remote sensing imagery can be an effective tool for the large scale detection of vegetation response to adverse impacts from climate change and support potential management practices such as increased monitoring and management of drought-affected areas. Different

  18. Mechanical characterization of densely welded Apache Leap tuff

    SciTech Connect

    Fuenkajorn, K.; Daemen, J.J.K.

    1991-06-01

    An empirical criterion is formulated to describe the compressive strength of the densely welded Apache Leap tuff. The criterion incorporates the effects of size, L/D ratio, loading rate and density variations. The criterion improves the correlation between the test results and the failure envelope. Uniaxial and triaxial compressive strengths, Brazilian tensile strength and elastic properties of the densely welded brown unit of the Apache Leap tuff have been determined using the ASTM standard test methods. All tuff samples are tested dry at room temperature (22 {plus_minus} 2{degrees}C), and have the core axis normal to the flow layers. The uniaxial compressive strength is 73.2 {plus_minus} 16.5 MPa. The Brazilian tensile strength is 5.12 {plus_minus} 1.2 MPa. The Young`s modulus and Poisson`s ratio are 22.6 {plus_minus} 5.7 GPa and 0.20 {plus_minus} 0.03. Smoothness and perpendicularity do not fully meet the ASTM requirements for all samples, due to the presence of voids and inclusions on the sample surfaces and the sample preparation methods. The investigations of loading rate, L/D radio and cyclic loading effects on the compressive strength and of the size effect on the tensile strength are not conclusive. The Coulomb strength criterion adequately represents the failure envelope of the tuff under confining pressures from 0 to 62 MPa. Cohesion and internal friction angle are 16 MPa and 43 degrees. The brown unit of the Apache Leap tuff is highly heterogeneous as suggested by large variations of the test results. The high intrinsic variability of the tuff is probably caused by the presence of flow layers and by nonuniform distributions of inclusions, voids and degree of welding. Similar variability of the properties has been found in publications on the Topopah Spring tuff at Yucca Mountain. 57 refs., 32 figs., 29 tabs.

  19. Biology and distribution of Lutzomyia apache as it relates to VSV

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Phlebotomine sand flies are vectors of bacteria, parasites, and viruses. Lutzomyia apache was incriminated as a vector of vesicular stomatitis viruses(VSV)due to overlapping ranges of the sand fly and outbreaks of VSV. I report on newly discovered populations of L. apache in Wyoming from Albany and ...

  20. Fort Apache Reservation Manpower Resources; Indian Manpower Resources in the Southwest. A Pilot Study.

    ERIC Educational Resources Information Center

    Taylor, Benjamin J.; O'Connor, Dennis J.

    Fort Apache Indians live in relative geographic and cultural isolation. The Apaches are younger than the general population, have a lower rate of overall labor-force participation, and typically work for the Federal Government or in trbal enterprises. A median family with 5 children subsists on a median annual family income of less than $1,000.…

  1. All-Indian Rodeo: A Transformation of Western Apache Tribal Warfare and Culture.

    ERIC Educational Resources Information Center

    Chavis, Ben

    1993-01-01

    Characteristics of All-Indian Rodeos held on the Fort Apache Reservation (Arizona) clearly reflect the evolution of historical patterns of tribal warfare and raiding. Rodeos provide the means to preserve Apache rituals, the warrior ideal, and traditional relationships with neighboring Navajo and Papago tribes. (SV)

  2. A Photographic Essay of Apache Children in Early Times, Volume 2-Part C.

    ERIC Educational Resources Information Center

    Thompson, Doris; Jacobs, Ben

    As part of a series of guides designed for instruction of American Indian children and youth, this resource guide constitutes a pictorial essay on life of the Apache child from 1880 to the early 20th century. Each of the 12 photographs is accompanied by an historical narrative which describes one or more cultural aspects of Apache childhood.…

  3. A Needs Assessment Study at Apache Junction for Long Range Planning.

    ERIC Educational Resources Information Center

    Gibson, Dale R.

    As part of an effort to assess the postsecondary educational needs of the community of Apache Junction, surveys were administered to: (1) students in grades 9-12 at Apache Junction High School (N=420) with regard to their educational plans, the postsecondary institutions they anticipated attending, course and program interests of those planning to…

  4. A Photographic Essay of Apache Chiefs and Warriors, Volume 2-Part B.

    ERIC Educational Resources Information Center

    Barkan, Gerald; Jacobs, Ben

    As part of a series designed for instruction of American Indian children and youth, this resource guide constitutes a pictorial essay describing forts, Indian agents, and Apache chiefs, warriors, and scouts of the 19th century. Accompanying each picture is a brief historical-biographical narrative. Focus is on Apache resistance to the reservation.…

  5. Evaluation of Apache Hadoop for parallel data analysis with ROOT

    NASA Astrophysics Data System (ADS)

    Lehrack, S.; Duckeck, G.; Ebke, J.

    2014-06-01

    The Apache Hadoop software is a Java based framework for distributed processing of large data sets across clusters of computers, using the Hadoop file system (HDFS) for data storage and backup and MapReduce as a processing platform. Hadoop is primarily designed for processing large textual data sets which can be processed in arbitrary chunks, and must be adapted to the use case of processing binary data files which cannot be split automatically. However, Hadoop offers attractive features in terms of fault tolerance, task supervision and control, multi-user functionality and job management. For this reason, we evaluated Apache Hadoop as an alternative approach to PROOF for ROOT data analysis. Two alternatives in distributing analysis data were discussed: either the data was stored in HDFS and processed with MapReduce, or the data was accessed via a standard Grid storage system (dCache Tier-2) and MapReduce was used only as execution back-end. The focus in the measurements were on the one hand to safely store analysis data on HDFS with reasonable data rates and on the other hand to process data fast and reliably with MapReduce. In the evaluation of the HDFS, read/write data rates from local Hadoop cluster have been measured and compared to standard data rates from the local NFS installation. In the evaluation of MapReduce, realistic ROOT analyses have been used and event rates have been compared to PROOF.

  6. The Influence of Alcoholic Liver Disease on Serum PIVKA-II Levels in Patients without Hepatocellular Carcinoma

    PubMed Central

    Kang, Keunhee; Kim, Ji Hoon; Kang, Seong Hee; Lee, Beom Jae; Seo, Yeon Seok; Yim, Hyung Joon; Yeon, Jong Eun; Park, Jong-Jae; Kim, Jae Seon; Bak, Young-Tae; Byun, Kwan Soo

    2015-01-01

    Background/Aims Prothrombin induced by vitamin K deficiency or antagonist II (PIVKA-II) is a widely used diagnostic marker for hepatocellular carcinoma (HCC). We evaluated the correlation between alcoholic liver disease (ALD) and serum PIVKA-II levels in chronic liver disease (CLD) patients. Methods We retrospectively reviewed the medical records of 2,528 CLD patients without HCC. Among these patients, 76 exhibited serum high PIVKA-II levels of >125 mAU/mL (group 1). We categorized 76 control patients matched by age, sex, and the presence of liver cirrhosis from the remaining patients who were negative for serum PIVKA-II (group 2). Results Group 1 revealed increased antibiotic usage (23.7% vs 2.6%, p<0.001) and incidence of ALD (60.5% vs 14.5%, p<0.001) as well as elevated aspartate aminotransferase (52.5 IU/L vs 30.5 IU/L, p=0.025) and γ glutamyl transpeptidase (67.5 IU/L vs 36.5 IU/L, p=0.005) levels compared with group 2. Further, group 1 was significantly associated with a worse Child-Pugh class than group 2. In the multivariate analysis, ALD (odds ratio [OR], 7.151; p<0.001) and antibiotic usage (OR, 5.846; p<0.001) were significantly associated with positive PIVKA-II levels. Conclusions Our study suggests that ALD and antibiotics usage may be confounding factors when interpreting high serum PIVKA-II levels in patients without HCC. Therefore, serum PIVKA-II levels in patients with ALD or in patients administered antibiotics should be interpreted with caution. PMID:25473073

  7. Prospective independent validation of APACHE III models in an Australian tertiary adult intensive care unit.

    PubMed

    Cook, D A; Joyce, C J; Barnett, R J; Birgan, S P; Playford, H; Cockings, J G L; Hurford, R W

    2002-06-01

    Evaluation of the performance of the APACHE III (Acute Physiology and Chronic Health Evaluation) ICU (intensive care unit) and hospital mortality models at the Princess Alexandra Hospital, Brisbane is reported. Prospective collection of demographic, diagnostic, physiological, laboratory, admission and discharge data of 5681 consecutive eligible admissions (1 January 1995 to 1 January 2000) was conducted at the Princess Alexandra Hospital, a metropolitan Australian tertiary referral medical/surgical adult ICU ROC (receiver operating characteristic) curve areas for the APACHE III ICU mortality and hospital mortality models demonstrated excellent discrimination. Observed ICU mortality (9.1%) was significantly overestimated by the APACHE III model adjusted for hospital characteristics (10.1%), but did not significantly differ from the prediction of the generic APACHE III model (8.6%). In contrast, observed hospital mortality (14.8%) agreed well with the prediction of the APACHE III model adjusted for hospital characteristics (14.6%), but was significantly underestimated by the unadjusted APACHE III model (13.2%). Calibration curves and goodness-of-fit analysis using Hosmer-Lemeshow statistics, demonstrated that calibration was good with the unadjusted APACHE III ICU mortality model, and the APACHE III hospital mortality model adjusted for hospital characteristics. Post hoc analysis revealed a declining annual SMR (standardized mortality rate) during the study period. This trend was present in each of the non-surgical, emergency and elective surgical diagnostic groups, and the change was temporally related to increased specialist staffing levels. This study demonstrates that the APACHE III model performs well on independent assessment in an Australian hospital. Changes observed in annual SMR using such a validated model support an hypothesis of improved survival outcomes 1995-1999. PMID:12075637

  8. Cohort vision study of Apache AH Mk1 pilots: protocol and methodology

    NASA Astrophysics Data System (ADS)

    Hiatt, Keith L.; Braithwaite, Malcolm G.; Crowley, John S.; Rash, Clarence E.; van de Pol, Corina; Ranchino, Daniel J.; Statz, William K.; Eke, Allison J.

    2002-08-01

    A collaborative occupational health study has been undertaken by Headquarters Director Army Aviation, Middle Wallop, UK, and the U.S. Army Aeromedical Research Laboratory, Fort Rucker, Alabama, to determine if the use of the monocular helmet-mounted display in the Apache AH Mk 1 attack helicopter has any long-term (10-year) effect on visual performance. This paper describes the protocol, methodology, development and initial execution phase of this study. The test methodology consists primarily of a battery of vision tests selected to capture changes in visual performance (with an emphasis on binocular visual functions) of Apache aviators over their flight career. It is anticipated that the number of Apache aviators will level out to approximately 70 by the end of the first three years of the study. Non-Apache aviators will serve as a control group.

  9. Apache Point Observatory Galactic Evolution Experiment (APOGEE) Spectrograph

    NASA Astrophysics Data System (ADS)

    Wilson, John C.; Hearty, F.; Skrutskie, M. F.; Majewski, S. R.; Schiavon, R.; Eisenstein, D.; Gunn, J.; Gillespie, B.; Weinberg, D.; Blank, B.; Henderson, C.; Smee, S.; Barkhouser, R.; Harding, A.; Hope, S.; Fitzgerald, G.; Stolberg, T.; Arns, J.; Nelson, M.; Brunner, S.; Burton, A.; Walker, E.; Lam, C.; Maseman, P.; Barr, J.; Leger, F.; Carey, L.; MacDonald, N.; Ebelke, G.; Beland, S.; Horne, T.; Young, E.; Rieke, G.; Rieke, M.; O'Brien, T.; Crane, J.; Carr, M.; Harrison, C.; Stoll, R.; Vernieri, M.; Holtzman, J.; Nidever, D.; Shetrone, M.; Allende-Prieto, C.; Johnson, J.; Frinchaboy, P.; Zasowski, G.; Garcia Perez, A.; Bizyaev, D.; Zhao, B.

    2012-01-01

    The Apache Point Observatory Galactic Evolution Experiment (APOGEE) will observe approximately 100,000 giant stars in the Milky Way with a dedicated fiber-fed (300 fibers from the Sloan 2.5-m telescope) near-infrared (1.5-1.7 micron) high resolution (R 22,500) spectrograph as part of the Sloan Digital Sky Survey III (SDSS-III). By observing in the near-infrared, APOGEE can uniformly sample all Milky Way stellar populations (bulge, thin/thick disks and halo) in the same survey to dramatically improve our understanding of the kinematical and chemical enrichment history of our galaxy. The instrument design includes several innovations: a novel fiber gang connector that allows simultaneous optical connection of 300 fibers from the instrument into swappable plug plate cartridges, the first deployed mosaic volume phase holographic (VPH) grating, and a very large ( 0.4-m) aperture six-element refractive camera incorporating crystalline silicon elements to image 300 spectra onto three HAWAII-IIRG detectors simultaneously.

  10. MaNGA: Mapping Nearby Galaxies at Apache Point Observatory

    NASA Astrophysics Data System (ADS)

    Bundy, Kevin

    2015-04-01

    I describe a new integral field spectroscopic survey called MaNGA (Mapping Nearby Galaxies at Apache Point Observatory). One of three core programs in the 6-year SDSS-IV project† that began on July 1st, 2014, MaNGA will deploy 17 fiber-bundle IFUs across the Sloan 2.5m Telescope's 3 degree field-of-view, targeting a mass-selected sample with a median redshift of 0.03, typical spatial resolution of 1-2 kpc, and a per-fiber signal-to-noise ratio of 4-8 in the outskirts of target galaxies. For each galaxy in the sample, MaNGA will provide maps and measured gradients of the composition and dynamics of both stars and gas. I discuss early results that highlight MaNGA's potential to shed light on the ionization and chemical enrichment of gas in galaxies, spatial patterns in their star formation histories, and the internal makeup of stellar populations. MaNGA's unprecedented data set will not only provide powerful new insight on galaxy formation and evolution but will serve as a valuable benchmark for future high-z observations from large telescopes and space-based facilities.

  11. MaNGA: Mapping Nearby Galaxies at Apache Point Observatory

    NASA Astrophysics Data System (ADS)

    Bundy, Kevin

    2015-01-01

    I present the design and execution of a new survey to obtain resolved spectroscopy for 10,000 nearby galaxies called MaNGA (Mapping Nearby Galaxies at Apache Point Observatory). One of three core programs in the 6-year SDSS-IV project that began on July 1st, 2014, MaNGA will deploy 17 fiber-bundle IFUs across the Sloan 2.5m Telescope's 3 degree field-of-view, targeting a mass-selected sample with a median redshift of 0.03, typical spatial resolution of 1-2 kpc, and a per-fiber signal-to-noise ratio of 4-8 in the outskirts of target galaxies. For each galaxy in the sample, MaNGA will provide maps and measured gradients of the composition and dynamics of both stars and gas. Early results highlight MaNGA's potential to shed light on the ionization and chemical enrichment of gas in galaxies, spatial patterns in their star formation histories, and the internal makeup of stellar populations. MaNGA's unprecedented data set will not only provide powerful new insight on galaxy formation and evolution but will serve as a valuable benchmark for future high-z observations from large telescopes as well as space-based facilities.

  12. Plasma Parameters in Io's Torus: Measurements from Apache Point Observatory

    NASA Astrophysics Data System (ADS)

    Turner, J.; Schmidt, C.; Schneider, N. M.; Chaffin, M.; McNeil, E.; Chanover, N.; Oza, A.; Rugenski, S.; Thelen, A.; Johnson, R. E.; Bittle, L.; King, P.

    2014-12-01

    The Io plasma torus is an astrophysical nebula wrapped around Jupiter, originating from the intense volcanic activity of Jupiter's moon Io. The torus varies both spatially and temporally, driven by changes in volcanism and asymmetries in the Jovian magnetosphere. We report results from 9 nights of observation spanning November 2013 to February 2014 with the Dual Imaging Spectrograph on the ARC 3.5m telescope at Apache Point Observatory in New Mexico. Emissions in these data include the [SII] doublets at 6716/6731A and 4069/4076A, [OII] at 3726/3729A, [SIII] at 3722A and 6312A, as well as resonantly scattered neutral [NaI] at 5890/5896A. Constraints on electron density, temperature and ion mixing rations can be obtained. Observations of both ansa during a 5 hour period characterize the complete longitudinal structure. Specifically, the intensity ratio of the collisionally excited [SII] doublet at 6716/6731A is a diagnostic for local electron density sampled at ~20 minute cadence. Absolute intensity can be derived directly from the reflectance of Jupiter's disc and standard calibrations are performed on the data such as bias subtraction, wavelength calibration and rectification. A unique background subtraction procedure is developed to disentangle scattered Jovian reflection and the torus. These observations were made in conjunction with JAXA's Hisaki mission, the HST auroral campaign and infrared monitoring of volcanism to better understand how mass and energy are transported throughout the system.

  13. APACHE IV Is Superior to MELD Scoring System in Predicting Prognosis in Patients after Orthotopic Liver Transplantation

    PubMed Central

    Zhang, Xianling; Liu, Yuan; Yan, Jun; Li, Tiehua; Hu, Ailing

    2013-01-01

    This study aims to compare the efficiency of APACHE IV with that of MELD scoring system for prediction of the risk of mortality risk after orthotopic liver transplantation (OLT). A retrospective cohort study was performed based on a total of 195 patients admitted to the ICU after orthotopic liver transplantation (OLT) between February 2006 and July 2009 in Guangzhou, China. APACHE IV and MELD scoring systems were used to predict the postoperative mortality after OLT. The area under the receiver operating characteristic curve (AUC) and the Hosmer-Lemeshow C statistic were used to assess the discrimination and calibration of APACHE IV and MELD, respectively. Twenty-seven patients died during hospitalization with a mortality rate of 13.8%. The mean scores of APACHE IV and MELD were 42.32 ± 21.95 and 18.09 ± 10.55, respectively, and APACHE IV showed better discrimination than MELD; the areas under the receiver operating characteristic curve for APACHE IV and MELD were 0.937 and 0.694 (P < 0.05 for both models), which indicated that the prognostic value of APACHE IV was relatively high. Both models were well-calibrated (The Hosmer-Lemeshow C statistics were 1.568 and 6.818 for APACHE IV and MELD, resp.; P > 0.05 for both). The respective Youden indexes of APACHE IV, MELD, and combination of APACHE IV with MELD were 0.763, 0.430, and 0.545. The prognostic value of APACHE IV is high but still underestimates the overall hospital mortality, while the prognostic value of MELD is poor. The function of the APACHE IV is, thus, better than that of the MELD. PMID:24348682

  14. APACHE IV is superior to MELD scoring system in predicting prognosis in patients after orthotopic liver transplantation.

    PubMed

    Hu, Yueyun; Zhang, Xianling; Liu, Yuan; Yan, Jun; Li, Tiehua; Hu, Ailing

    2013-01-01

    This study aims to compare the efficiency of APACHE IV with that of MELD scoring system for prediction of the risk of mortality risk after orthotopic liver transplantation (OLT). A retrospective cohort study was performed based on a total of 195 patients admitted to the ICU after orthotopic liver transplantation (OLT) between February 2006 and July 2009 in Guangzhou, China. APACHE IV and MELD scoring systems were used to predict the postoperative mortality after OLT. The area under the receiver operating characteristic curve (AUC) and the Hosmer-Lemeshow C statistic were used to assess the discrimination and calibration of APACHE IV and MELD, respectively. Twenty-seven patients died during hospitalization with a mortality rate of 13.8%. The mean scores of APACHE IV and MELD were 42.32 ± 21.95 and 18.09 ± 10.55, respectively, and APACHE IV showed better discrimination than MELD; the areas under the receiver operating characteristic curve for APACHE IV and MELD were 0.937 and 0.694 (P < 0.05 for both models), which indicated that the prognostic value of APACHE IV was relatively high. Both models were well-calibrated (The Hosmer-Lemeshow C statistics were 1.568 and 6.818 for APACHE IV and MELD, resp.; P > 0.05 for both). The respective Youden indexes of APACHE IV, MELD, and combination of APACHE IV with MELD were 0.763, 0.430, and 0.545. The prognostic value of APACHE IV is high but still underestimates the overall hospital mortality, while the prognostic value of MELD is poor. The function of the APACHE IV is, thus, better than that of the MELD.

  15. A Western apache writing system: the symbols of silas john.

    PubMed

    Basso, K H; Anderson, N

    1973-06-01

    At the outset of this article, it was observed that the adequacy of an etic typology of written symbols could be judged by its ability to describe all the emic distinctions in all the writing systems of the world. In conclusion, we should like to return to this point and briefly examine the extent to which currently available etic concepts can be used to describe the distinctions made by Western Apaches in relation to the writing system of Silas John. Every symbol in the Silas John script may be classified as a phonetic-semantic sign. Symbols of this type denote linguistic expressions that consist of one or more words and contrast as a class with phonetic-nonsemantic signs, which denote phonemes (or phoneme clusters), syllables (or syllable clusters), and various prosodic phenomena (2, pp. 2, 248). Phonetic semantic signs are commonly partitioned into two subclasses: alogographs (which denote single words) and phraseographs (which denote on or more words). Although every symbol in the Silas John script can be assigned to one or the other of these categories, such an exercise is without justification (21). We have no evidence to suggest that Western Apaches classify symbols according to the length or complexity of their linguistic referents, and therefore the imposition of distinctions based on these criteria would be inappropriate and misleading. A far more useful contrast, and one we have already employed, is presented in most etic typologies as an opposition between compound (composite) and noncompound (noncomposite) symbols. Used to break down the category of phonetic-semantic signs, these two concepts enable us to describe more or less exactly the distinction Apaches draw between "symbol elements put together" (ke?escin ledidilgoh) and "symbol elements standing alone" (ke?- escin doledidildaahi). The former may now be defined as consisting of compound phonetic-semantic signs, while the latter is composed of noncompound phonetic-semantic signs. Up to this point

  16. A Tour of Big Data, Open Source Data Management Technologies from the Apache Software Foundation

    NASA Astrophysics Data System (ADS)

    Mattmann, C. A.

    2012-12-01

    The Apache Software Foundation, a non-profit foundation charged with dissemination of open source software for the public good, provides a suite of data management technologies for distributed archiving, data ingestion, data dissemination, processing, triage and a host of other functionalities that are becoming critical in the Big Data regime. Apache is the world's largest open source software organization, boasting over 3000 developers from around the world all contributing to some of the most pervasive technologies in use today, from the HTTPD web server that powers a majority of Internet web sites to the Hadoop technology that is now projected at over a $1B dollar industry. Apache data management technologies are emerging as de facto off-the-shelf components for searching, distributing, processing and archiving key science data sets both geophysical, space and planetary based, all the way to biomedicine. In this talk, I will give a virtual tour of the Apache Software Foundation, its meritocracy and governance structure, and also its key big data technologies that organizations can take advantage of today and use to save cost, schedule, and resources in implementing their Big Data needs. I'll illustrate the Apache technologies in the context of several national priority projects, including the U.S. National Climate Assessment (NCA), and in the International Square Kilometre Array (SKA) project that are stretching the boundaries of volume, velocity, complexity, and other key Big Data dimensions.

  17. Jicarilla Apache Utility Authority Renewable Energy and Energy Efficiency Strategic Planning

    SciTech Connect

    Rabago, K.R.

    2008-06-28

    The purpose of this Strategic Plan Report is to provide an introduction and in-depth analysis of the issues and opportunities, resources, and technologies of energy efficiency and renewable energy that have potential beneficial application for the people of the Jicarilla Apache Nation and surrounding communities. The Report seeks to draw on the best available information that existed at the time of writing, and where necessary, draws on new research to assess this potential. This study provides a strategic assessment of opportunities for maximizing the potential for electrical energy efficiency and renewable energy development by the Jicarilla Apache Nation. The report analyzes electricity use on the Jicarilla Apache Reservation in buildings. The report also assesses particular resources and technologies in detail, including energy efficiency, solar, wind, geothermal, biomass, and small hydropower. The closing sections set out the elements of a multi-year, multi-phase strategy for development of resources to the maximum benefit of the Nation.

  18. Preliminary Assessment of Apache Hopefulness: Relationships with Hopelessness and with Collective as well as Personal Self-Esteem

    ERIC Educational Resources Information Center

    Hammond, Vanessa Lea; Watson, P. J.; O'Leary, Brian J.; Cothran, D. Lisa

    2009-01-01

    Hopelessness is central to prominent mental health problems within American Indian (AI) communities. Apaches living on a reservation in Arizona responded to diverse expressions of hope along with Hopelessness, Personal Self-Esteem, and Collective Self-Esteem scales. An Apache Hopefulness Scale expressed five themes of hope and correlated…

  19. The Roles of Literacy and Collaboration in Documenting Native American Languages: A Report from the Jicarilla Apache Dictionary Project.

    ERIC Educational Resources Information Center

    Axelrod, Melissa; de Garcia, Jule Gomez; Lachler, Jordan

    2003-01-01

    Reports on the progress of a project to produce a dictionary of the Jicarilla Apache language. Jicarilla, an Eastern Apachean language is spoken on the Jicarilla Apache reservation in Northern New Mexico. The project has revealed much about the role of literacy in language standardization and in speaker empowerment. Suggests that many parallels…

  20. 78 FR 11677 - Notice of Inventory Completion: U.S. Department of Agriculture, Forest Service, Apache-Sitgreaves...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ..., Apache-Sitgreaves National Forests, Springerville, AZ, and the Field Museum of Natural History, Chicago... Agriculture (USDA), Forest Service, Apache-Sitgreaves National Forests and the Field Museum of Natural History... completion of an inventory of human remain under the control of the USDA, Forest Service,...

  1. Acute physiology, age, and chronic health evaluation (APACHE) III score is an alternative efficient predictor of mortality in burn patients.

    PubMed

    Tanaka, Yohei; Shimizu, Mikio; Hirabayashi, Hidemitsu

    2007-05-01

    The present study was performed to evaluate the prognostic value of the acute physiology, age, chronic health evaluation (APACHE) III score in burn patients. We hypothesised that APACHE III score efficiently predicts mortality of burn patients as it reflects the physiological changes in the acute phase and the severity of the underlying illness. Data such as age, gender, inhalation injury, total burn surface area (TBSA), burn index (BI), prognostic burn index (PBI), APACHE III score and outcome of 105 hospitalised patients were analysed retrospectively. TBSA, BI, PBI, and APACHE III score in the mortality group were significantly higher than those of surviving group. The mean scores of surviving versus mortality groups were as follows: TBSA, 19.2+/-17.8% versus 69.1+/-28.4%, p<0.0001; BI, 12.8+/-13.1% versus 66.8+/-28.6%, p<0.0001; PBI, 68.8+/-26.0% versus 124.4+/-33.6%, p<0.0001; APACHE III score, 28.4+/-22.2% versus 71.3+/-32.1%, p<0.0001. PBI and APACHE III score showed marked associations between higher scores and higher mortality. APACHE III score showed a significant correlation with PBI (p<0.0001). The present study suggested that APACHE III score could be used as an alternative efficient predictor of mortality in burn patients.

  2. The case against using the APACHE system to predict intensive care unit outcome in trauma patients.

    PubMed

    Vassar, M J; Holcroft, J W

    1994-01-01

    The use of outcome indices as a means of evaluating institutional performance for delivery of medical care is at the forefront of federal health policy reforms. Because an enormous number of clinical and financial data are generated by ICU patients, it is inevitable that integrated bedside computers will be necessary to supply the type of information that is being sought by governmental and private insurance agencies involved in assessment of hospital performance. The Health Care Financing Administration already has adopted the APACHE data collection protocols and predictive models for the severity of illness adjustments that were used in assessing the 1986 hospital-specific death rate for acute myocardial infarction, congestive heart failure, stroke, and pneumonia. In our opinion, however, it is unlikely that any single system will be developed that can accurately estimate more than 50% of ICU deaths. The intention of the APACHE III system to include 78 diagnostic categories seems unrealistic. Furthermore, the number of data needed to document outcomes for both low- and high-risk admissions is impractical. We are evaluating APACHE III to determine whether the revisions to the definition for head trauma will represent a significant improvement in predicting outcomes for trauma patients. In the interim, the financial investment in the APACHE III automated bedside data collection system cannot be justified for trauma patients. Neither should it be used in ICUs that admit a large number of trauma patients as a tool for monitoring unit efficiency, guiding triage decisions, allocating staff and ICU beds, identifying risks of iatrogenic or other potential complications, or assessing quality of life, in spite of marketing efforts by the APACHE Corporation. We believe that using any of the APACHE systems for these purposes, at best, is premature, and potentially misrepresents the trauma patient population. Standards for patient classification already are in place for use

  3. The Apache Point Observatory Lunar Laser-ranging Operation: Instrument Description and First Detections

    SciTech Connect

    Murphy, TW; Adelberger, Eric G.; Battat, J.; Carey, LN; Hoyle, Charles D.; LeBlanc, P.; Michelsen, EL; Nordtvedt, K.; Orin, AE; Strasburg, Jana D.; Stubbs, CW; Swanson, HE; Williams, E.

    2008-01-01

    A next-generation lunar laser ranging apparatus using the 3.5 m telescope at the Apache Point Observatory in southern New Mexico has begun science operation. APOLLO (the Apache Point Observatory Lunar Laser-ranging Operation) has achieved one-millimeter range precision to the moon which should lead to aproximately one-orderof-magnitude improvements in the precision of several tests of fundamental properties of gravity. We briefly motivate the scientific goals, and then give a detailed discussion of the APOLLO instrumentation.

  4. Utilizing findings from the APACHE III research to develop operational information system for the ICU--the APACHE III ICU Management System.

    PubMed

    Knaus, W A; Draper, E A; Wagner, D P

    1991-01-01

    The APACHE III data base reflects the disease, physiologic status, and outcome data from 17,400 ICU patients at 40 hospitals, 26 of which were randomly selected from representative geographic regions, bed size, and teaching status. This provides a nationally representative standard for measuring several important aspects of ICU performance. Results from the study have now been used to develop an automated information system to provide real time information about expected ICU patient outcome, length of stay, production cost, and ICU performance. The information system provides several new capabilities to ICU clinicians, clinic, and hospital administrators. Among the system's capabilities are: the ability to compare local ICU performance against predetermined criteria; the ability to forecast nursing requirements; and, the ability to make both individual and group patient outcome predictions. The system also provides improved administrative support by tracking ICU charges at the point of origin and reduces staff workload eliminating the requirement for several manually maintained logs and patient lists. APACHE III has the capability to electronically interface with and utilize data already captured in existing hospital information systems, automated laboratory information systems, and patient monitoring systems. APACHE III will also be completely integrated with several CIS vendors' products.

  5. A phase II study of TRC105 in patients with hepatocellular carcinoma who have progressed on sorafenib

    PubMed Central

    Duffy, AG; Ulahannan, SV; Cao, L; Rahma, OE; Makarova-Rusher, OV; Kleiner, DE; Fioravanti, S; Walker, M; Carey, S; Yu, Y; Venkatesan, AM; Turkbey, B; Choyke, P; Trepel, J; Bollen, KC; Steinberg, SM; Figg, WD

    2015-01-01

    Background Endoglin is an endothelial cell membrane receptor essential for angiogenesis and highly expressed on the vasculature of many tumor types, including hepatocellular carcinoma (HCC). TRC105 is a chimeric IgG1 anti-CD105 monoclonal antibody that inhibits angiogenesis and tumor growth by endothelial cell growth inhibition, ADCC and apoptosis, and complements VEGF inhibitors. Objective The aim of this phase II study was to evaluate the efficacy of anti-endoglin therapy with TRC105 in patients with advanced HCC, post-sorafenib. Methods Patients with HCC and compensated liver function (Childs-Pugh A/B7), ECOG 0/1, were enrolled to a single-arm, phase II study of TRC105 15 mg/kg IV every two weeks. Patients must have progressed on or been intolerant of prior sorafenib. A Simon optimal two-stage design was employed with a 50% four-month PFS target for progression to the second stage. Correlative biomarkers evaluated included DCE-MRI as well as plasma levels of angiogenic biomarkers and soluble CD105. Results A total accrual of 27 patients was planned. However, because of lack of efficacy and in accordance with the Simon two-stage design, 11 patients were enrolled. There were no grade 3/4 treatment-related toxicities. Most frequent toxicities were headache (G2; N = 3) and epistaxis (G1; N = 4). One patient had a confirmed partial response by standard RECIST criteria and biologic response on DCE-MRI but the four-month PFS was insufficient to proceed to the second stage of the study. Conclusions: TRC105 was well tolerated in this HCC population following sorafenib. Although there was evidence of clinical activity, this did not meet prespecified criteria to proceed to the second stage. TRC105 development in HCC continues as combination therapy with sorafenib. PMID:26535124

  6. White Mountain Apache Language: Issues in Language Shift, Textbook Development, and Native Speaker-University Collaboration.

    ERIC Educational Resources Information Center

    Adley-SantaMaria, Bernadette

    This paper is an overview of topics covered at two sessions of the Fourth Annual Stabilizing Indigenous Languages Symposium, from the perspective of a native speaker of an indigenous language and member of a university academic community. The first section describes a Master's thesis on White Mountain Apache (WMA) language shift. Interviews with…

  7. A Season on the Reservation: My Sojourn with the White Mountain Apache.

    ERIC Educational Resources Information Center

    Abdul-Jabbar, Kareem; Singular, Stephen

    In this book, basketball legend Kareem Abdul-Jabbar tells of one basketball season when he coached a high school team on the White Mountain Apache Reservation (Arizona). Tired of life in Los Angeles, disillusioned with pro basketball, and devastated by the death of his mother, Abdul-Jabbar accepted an invitation to coach the team at Alchesay High…

  8. Pathogens and bionomics of Lutzomyia apache (Diptera: Psychodidae) from Wyoming, USA

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Phlebotomine sand flies are vectors of bacteria, parasites, and viruses. Lutzomyia apache, a North American sand fly, was incriminated as a vector of vesicular stomatitis viruses (VSV) due to overlapping ranges of the sand fly and recent outbreaks of VSV. We report on the discovery of two population...

  9. Effectiveness of High School Curricula for the Transition of Apache Special and General Education Students.

    ERIC Educational Resources Information Center

    Ramasamy, Rangasamy

    1995-01-01

    Special education (n=52) and general education (n=54) students who attended an Apache Indian reservation high school were interviewed 0 to 4 years after graduating or leaving school. Both groups reported that they found mathematics and English most helpful and that they wished for more computer, business, and office skills training. (DB)

  10. "The Story of Custer in Everything but Name?": Colonel Thursday and "Fort Apache."

    ERIC Educational Resources Information Center

    Neale, Steve

    1995-01-01

    Analyzes similarities and differences between Henry Fonda's character Colonel Thursday in John Ford's "Fort Apache" and the historical figure of General George Armstrong Custer. States that historical parallels between Thursday's military defeat and Custer's are, for the most part, fairly obvious. (PA)

  11. Making Contact: Working with the White Mountain Apache on "Indian Summer."

    ERIC Educational Resources Information Center

    Sabal, Rob

    1997-01-01

    Chronicles the author's experience of working with a group of Apache actors and cultural experts on the production of a feature-length narrative, "Indian Summer." Finds that, in this case, the process of cross-cultural collaboration was successful in uniting different people from different cultures in a common purpose. (PA)

  12. A Photographic Essay of the San Carlos Apache Indians, Volume 2-Part A.

    ERIC Educational Resources Information Center

    Soto, Ed; And Others

    As part of a series of guides designed for instruction of American Indian children and youth, this resource guide constitutes a pictorial essay on the San Carlos Apache Reservation founded in the late 1800's and located in Arizona's Gila County. An historical narrative and discussion questions accompany each of the 12 photographs. Photographic…

  13. Lutzomyia (Helcocyrtomyia) Apache Young and Perkins (Diptera: Psychodidae) feeds on reptiles

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Phlebotomine sand flies are vectors of bacteria, parasites, and viruses. In the western USA a sand fly, Lutzomyia apache Young and Perkins, was initially associated with epizootics of vesicular stomatitis virus (VSV), because sand flies were trapped at sites of an outbreak. Additional studies indica...

  14. Language Use by Yavapai-Apache Students with Recommendations for Curriculum Design.

    ERIC Educational Resources Information Center

    McCarty, Teresa L.

    1980-01-01

    Bilingual Yavapai-Apache youth have some Yavapai linguistic competence and limited performance skills, yet Yavapai is important to them. A bicultural-bilingual curriculum emphasizing culture and history minicourses taught by community members can help revitalize the fading Yavapai culture and provide cross-cultural education for non-Indians as…

  15. Post-High School Employment: A Follow-Up of Apache Native American Youth.

    ERIC Educational Resources Information Center

    Ramasamy, Rangasamy

    1996-01-01

    Interviews with 106 Apache Native American youth (including 52 who received special education services) who had exited high school between 1988 and 1992 found that 14 special education and 19 general education students were employed. Results are discussed in light of curriculum, cultural implications of employment, and federally mandated…

  16. A Photographic Essay of Apache Clothing, War Charms, and Weapons, Volume 2-Part D.

    ERIC Educational Resources Information Center

    Thompson, Doris; Jacobs, Ben

    As part of a series of guides designed for instruction of American Indian children and youth, this resource guide constitutes a pictorial essay on Apache clothing, war charms, and weaponry. A brief historical introduction is followed by 21 question suggestions for classroom use. Each of the 12 photographic topics is accompanied by a descriptive…

  17. Survival of Apache Trout eggs and alevins under static and fluctuating temperature regimes

    USGS Publications Warehouse

    Recsetar, Matthew S.; Bonar, Scott A.

    2013-01-01

    Increased stream temperatures due to global climate change, livestock grazing, removal of riparian cover, reduction of stream flow, and urbanization will have important implications for fishes worldwide. Information exists that describes the effects of elevated water temperatures on fish eggs, but less information is available on the effects of fluctuating water temperatures on egg survival, especially those of threatened and endangered species. We tested the posthatch survival of eyed eggs and alevins of Apache Trout Oncorhynchus gilae apache, a threatened salmonid, in static temperatures of 15, 18, 21, 24, and 27°C, and also in treatments with diel fluctuations of ±3°C around those temperatures. The LT50 for posthatch survival of Apache Trout eyed eggs and alevins was 17.1°C for static temperatures treatments and 17.9°C for the midpoints of ±3°C fluctuating temperature treatments. There was no significant difference in survival between static temperatures and fluctuating temperatures that shared the same mean temperature, yet there was a slight difference in LT50s. Upper thermal tolerance of Apache Trout eyed eggs and alevins is much lower than that of fry to adult life stages (22–23°C). Information on thermal tolerance of early life stages (eyed egg and alevin) will be valuable to those restoring streams or investigating thermal tolerances of imperiled fishes.

  18. 77 FR 51475 - Safety Zone; Apache Pier Labor Day Fireworks; Myrtle Beach, SC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    ... establishing a temporary safety zone on the waters of the Atlantic Ocean in the vicinity of Apache Pier in... life and property on the navigable waters of the Atlantic Ocean off the coast of Myrtle Beach, SC... INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal Register NPRM Notice of...

  19. 77 FR 18997 - Rim Lakes Forest Restoration Project; Apache-Sitgreavese National Forest, Black Mesa Ranger...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... Forest Service Rim Lakes Forest Restoration Project; Apache-Sitgreavese National Forest, Black Mesa... action can meet its restoration objectives, and to assure consistency with the forest plan. Information... Healthy Forest Restoration Act (HFRA) of 2003, following regulations at 36 CFR part 218. To date,...

  20. 75 FR 68607 - BP Canada Energy Marketing Corp. Apache Corporation; Notice for Temporary Waivers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission BP Canada Energy Marketing Corp. Apache Corporation; Notice for Temporary Waivers November 1, 2010. Take notice that on October 29, 2010, BP Canada Energy Marketing Corp....

  1. Performance of APACHE III over time in Australia and New Zealand: a retrospective cohort study.

    PubMed

    Paul, E; Bailey, M; Van Lint, A; Pilcher, V

    2012-11-01

    The Acute Physiology and Chronic Health Evaluation (APACHE) III-j model has been used for benchmarking intensive care unit (ICU) outcomes in Australia and New Zealand for over a decade. This study assessed performance of the APACHE III-j model in adult patients admitted to Australasian ICUs during a ten-year period. Data were extracted from the Australian and New Zealand Intensive Care Society Adult Patient Database. Performance of APACHE III-j at different time points and within different age strata was evaluated by dividing the whole cohort into five 'two-year' groups. Calibration and discrimination were assessed by the Brier score, Hosmer-Lemeshow C and H statistics, Standardised Mortality Ratio (SMR), Cox calibration regression, calibration curves and area under the receiver operating characteristic curve (AUROC). Model performance within diagnostic categories was evaluated. Between 1 January 2000 and 31 December 2009, 558,585 ICU admissions which met inclusion criteria were included in the analysis. The mean (standard deviation) age was 60.8 (18.4) years and 58.3% were male. Overall observed mortality was 12.6%. The mean (standard deviation) APACHE III-j predicted mortality was 14.5% (21.8). Although discrimination (as measured by AUROC) was preserved over time, all other markers of model performance showed deterioration. There was a significant decrease in SMR in eight of ten most common diagnoses examined. This study demonstrates that performance of APACHE III-j model has deteriorated in Australasian hospitals and there is now a clear need for an updated modelling approach to improve mortality prediction, performance monitoring and quality of research undertaken in Australian and New Zealand ICUs.

  2. Sorafenib plus hepatic arterial infusion chemotherapy with cisplatin versus sorafenib for advanced hepatocellular carcinoma: randomized phase II trial

    PubMed Central

    Ikeda, M.; Shimizu, S.; Sato, T.; Morimoto, M.; Kojima, Y.; Inaba, Y.; Hagihara, A.; Kudo, M.; Nakamori, S.; Kaneko, S.; Sugimoto, R.; Tahara, T.; Ohmura, T.; Yasui, K.; Sato, K.; Ishii, H.; Furuse, J.; Okusaka, T.

    2016-01-01

    Background Sorafenib (Sor) is acknowledged as a standard therapy for advanced hepatocellular carcinoma (HCC). This trial was conducted to evaluate the effect of addition of hepatic arterial infusion chemotherapy with cisplatin (SorCDDP) to Sor for the treatment of advanced HCC. Patients and methods We conducted a multicenter open-labeled randomized phase II trial in chemo-naïve patients with advanced HCC with Child-Pugh scores of 5–7. Eligible patients were randomly assigned 2:1 to receive SorCDDP (sorafenib: 400 mg bid; cisplatin: 65 mg/m2, day 1, every 4–6 weeks) or Sor (400 mg bid). The primary end point was overall survival. Results A total of 108 patients were randomized (Sor, n = 42; SorCDDP, n = 66). The median survival in the Sor and SorCDDP arms were 8.7 and 10.6 months, respectively [stratified hazard ratio (95% confidence interval), 0.60 (0.38–0.96), P = 0.031]. The median time to progression and the response rate were, respectively, 2.8 months and 7.3% in the Sor arm and 3.1 months and 21.7% in the SorCDDP arm. The adverse events were more frequent in the SorCDDP arm than in the Sor arm, but well-tolerated. Conclusion SorCDDP yielded favorable overall survival when compared with Sor in patients with advanced HCC. Clinical Trial registration UMIN-CTR (http://www.umin.ac.jp/ctr/index-j.htm), identification number: UMIN000005703. PMID:27573564

  3. Constraints on Small-size Planet Occurrence around Nearby Early-to-mid M Dwarfs from the APACHE Project

    NASA Astrophysics Data System (ADS)

    Giacobbe, P.

    2015-10-01

    APACHE [1] is a ground-based photometric survey intended to find planets transiting the closest and smallest main-sequence stars. Here, we try to answer an outstanding question: in light of the bounty of small planets transiting small stars uncovered by the Kepler mission, should APACHE have found one planet so far? We estimate APACHE's ensemble sensitivity to exoplanets by performing end-to-end simulations of observations of ~350 nearby early-tomid M dwarfs, gathered by APACHE between 2012 July and 2015 August. For 2- 10 R ⊕ planets, we compare this sensitivity to results from Kepler [2] and MEarth ground-based photometric survey [3]. APACHE is sensitive to transits of planets the size of Neptune. In light of this sensitivity, we discuss our lack of detections of transiting Neptunes based on the analysis of the first three years of survey data, and compare our results with known populations of Neptune-sized exoplanets around nearby early M dwarfs, discovered by both radial velocity and transit surveys. Furthermore, we put in context these results with the preliminary statistics of an M-dwarf survey mfrom HARPSN@TNG within the large programme GAPS (Global Architecture of Planetary Systems [4]), focused on targets under monitoring with APACHE.

  4. A simple tool for mortality prediction in burns patients: APACHE III score and FTSA.

    PubMed

    Moore, E C; Pilcher, D V; Bailey, M J; Cleland, H; McNamee, J

    2010-11-01

    Prediction of outcome for patients with major thermal injury is important to inform clinical decision making, alleviate individual suffering and improve hospital resource allocation. Age and burn size are widely accepted as the two largest contributors of mortality amongst burns patients. The APACHE (Acute Physiology and Chronic Health Evaluation) III-j score, which incorporates patient age, is also useful for mortality prediction, of intensive care populations. Validation for the burns specific cohort is unclear. A retrospective cohort study was performed on patients admitted to the Intensive Care Unit (ICU) via the Victorian Adult Burns Service (VABS), to compare observed mortality with burns specific markers of illness severity and APACHE III-j score. Our primary aim was to develop a mortality prediction tool for the burns population. Between January 1, 2002 and December 31, 2008, 228 patients were admitted to the ICU at The Alfred with acute burns. The mean age was 45.6 years and 81% (n=184) were male. Patients had severe injuries: the average percent TBSA (total body surface area) was 28% (IQR 10-40) and percent FTSA (full thickness surface area) was 18% (IQR 10-25). 86% (n=197) had airway involvement. Overall mortality in the 7-year period was 12% (n=27). Non-survivors were older, had larger and deeper burns, a higher incidence of deliberate self-harm, higher APACHE III-j scores and spent less time in hospital (but similar time in ICU), compared with survivors. Independent risk factors for death were percent FTSA (OR 1.03, 95% CI 1.01-1.05, p=0.01) and APACHE III-j score (OR 1.04, 95% CI 1.02-1.07, p<0.001). Mortality prediction based on both of these variables in combination was more specific than either individual variable alone (AUROC 0.85, 95% CI 0.79-0.92). Likelihood of death for patients with severe thermal injury can be predicted with accuracy from APACHE III-j score and percent FTSA. Prospective validation of our model on different burn populations

  5. Apache Trail uranium prospect, White Signal district, Grant County, New Mexico

    USGS Publications Warehouse

    Bauer, Herman L.

    1951-01-01

    The Apache Trail uranium prospect in the White Signal district, Grant County. N. Mex., was mapped by the Geological Survey in May 1950. Pre-Cambrian granite is cut by a diabase dike and a parallel quartz-hematite vein, both of which strike easterly and dip 60 to 65 degrees north. Small quantities of copper carbonates and bismuth-gold ore have been mined. The quartz-hematite vein is moderately radioactive and, although no uranium minerals were seen, two samples contained about 0.01 percent uranium. The diabase dike locally contains torbernite. Two samples of diabase contained about 0.04 percent uranium.

  6. Design of the Apache Point Observatory 3.5 M telescope. V - Telescope enclosure thermal modeling

    NASA Astrophysics Data System (ADS)

    Siegmund, Walter A.

    1990-07-01

    A 3.5 m telescope is under construction at Apache Point near Alamogordo, New Mexico, at an elevation of 2800 m. A thermal model of a telescope enclosure is described. The model evaluates various strategies for minimizing local sources of image degradation (dome seeing). Direct and diffuse insolation, radiation to the sky, conduction, and the thermal inertia of the walls, interior air, roof, and structural steel are included. It is observed that highly reflective surface coatings reduce heat absorbed during the day, but are not very effective in reducing heat transfer in the telescope chamber at night, assuming that components with large heat capacities or thermal time constants are insulated.

  7. Nonsuicidal Self-Injury in an American Indian Reservation Community: Results from the White Mountain Apache Surveillance System, 2007-2008

    ERIC Educational Resources Information Center

    Cwik, Mary F.; Barlow, Allison; Tingey, Lauren; Larzelere-Hinton, Francene; Goklish, Novalene; Walkup, John T.

    2011-01-01

    Objective: To describe characteristics and correlates of nonsuicidal self-injury (NSSI) among the White Mountain Apache Tribe. NSSI has not been studied before in American Indian samples despite associated risks for suicide, which disproportionately affect American Indian youth. Method: Apache case managers collected data through a tribally…

  8. Geronimo's Kids: A Teacher's Lessons on the Apache Reservation. Elma Dill Russell Spencer Series in the West and Southwest, No. 16.

    ERIC Educational Resources Information Center

    Ove, Robert S.; Stockel, H. Henrietta

    In 1948, a young and naive Robert Ove arrived at Whitetail, on the Mescalero Apache Reservation, to teach at the Bureau of Indian Affairs day school. Living there were the Chiricahua Apaches--descendants of Geronimo and the survivors of nearly 30 years of incarceration by the U.S. government. With help from Indian historian H. Henrietta Stockel,…

  9. Stromatolites of the Mescal Limestone (Apache Group, middle Proterozoic, central Arizona): taxonomy, biostratigraphy, and paleoenvironments.

    PubMed

    Bertrand-Sarfati, J; Awramik, S M

    1992-09-01

    The 25- to 30-m-thick Algal Member of the Mescal Limestone (middle Proterozoic Apache Group) contains two distinct stromatolitic units: at the base, a 2- to 3-m-thick unit composed of columnar stromatolites and above, a thicker unit of stratiform and pseudocolumnar stromatolites. Columnar forms from the first unit belong to the Group Tungussia, and two new Forms are described: T. mescalita and T. chrysotila. Among the pseudocolumnar stromatolites of the thicker unit, one distinctive new taxon, Apachina henryi, is described. Because of the low stromatolite diversity, the biostratigraphic value of this assemblage is limited. The presence of Tungussia is consistent with the generally accepted isotopic age for the Apache Group of 1200 to 1100 Ma. The Mescal stromatolites do not closely resemble any other known Proterozoic stromatolites in the southwestern United States or northwestern Mexico. Analyses of sedimentary features and stromatolite growth forms suggest deposition on a stable, flat, shallow, subtidal protected platform during phases of Tungussia growth. Current action probably influenced the development of columns, pseudocolumns, and elongate stromatolitic ridges; these conditions alternated with phases of relatively quiet water characterized by nonoriented stromatolitic domes and stratiform stromatolites. Stable conditions favorable for development of the Mescal stromatolites were short-lived and did not permit the development of thick, stromatolite-bearing units such as those characteristic of many Proterozoic sequences elsewhere.

  10. Stromatolites of the Mescal Limestone (Apache Group, middle Proterozoic, central Arizona): taxonomy, biostratigraphy, and paleoenvironments

    NASA Technical Reports Server (NTRS)

    Bertrand-Sarfati, J.; Awramik, S. M.

    1992-01-01

    The 25- to 30-m-thick Algal Member of the Mescal Limestone (middle Proterozoic Apache Group) contains two distinct stromatolitic units: at the base, a 2- to 3-m-thick unit composed of columnar stromatolites and above, a thicker unit of stratiform and pseudocolumnar stromatolites. Columnar forms from the first unit belong to the Group Tungussia, and two new Forms are described: T. mescalita and T. chrysotila. Among the pseudocolumnar stromatolites of the thicker unit, one distinctive new taxon, Apachina henryi, is described. Because of the low stromatolite diversity, the biostratigraphic value of this assemblage is limited. The presence of Tungussia is consistent with the generally accepted isotopic age for the Apache Group of 1200 to 1100 Ma. The Mescal stromatolites do not closely resemble any other known Proterozoic stromatolites in the southwestern United States or northwestern Mexico. Analyses of sedimentary features and stromatolite growth forms suggest deposition on a stable, flat, shallow, subtidal protected platform during phases of Tungussia growth. Current action probably influenced the development of columns, pseudocolumns, and elongate stromatolitic ridges; these conditions alternated with phases of relatively quiet water characterized by nonoriented stromatolitic domes and stratiform stromatolites. Stable conditions favorable for development of the Mescal stromatolites were short-lived and did not permit the development of thick, stromatolite-bearing units such as those characteristic of many Proterozoic sequences elsewhere.

  11. Sideloading - Ingestion of Large Point Clouds Into the Apache Spark Big Data Engine

    NASA Astrophysics Data System (ADS)

    Boehm, J.; Liu, K.; Alis, C.

    2016-06-01

    In the geospatial domain we have now reached the point where data volumes we handle have clearly grown beyond the capacity of most desktop computers. This is particularly true in the area of point cloud processing. It is therefore naturally lucrative to explore established big data frameworks for big geospatial data. The very first hurdle is the import of geospatial data into big data frameworks, commonly referred to as data ingestion. Geospatial data is typically encoded in specialised binary file formats, which are not naturally supported by the existing big data frameworks. Instead such file formats are supported by software libraries that are restricted to single CPU execution. We present an approach that allows the use of existing point cloud file format libraries on the Apache Spark big data framework. We demonstrate the ingestion of large volumes of point cloud data into a compute cluster. The approach uses a map function to distribute the data ingestion across the nodes of a cluster. We test the capabilities of the proposed method to load billions of points into a commodity hardware compute cluster and we discuss the implications on scalability and performance. The performance is benchmarked against an existing native Apache Spark data import implementation.

  12. Acral pseudolymphomatous angiokeratoma of children (APACHE)-like eruption in adult identical twins.

    PubMed

    Fonia, A; Bhatt, N; Robson, A; Kennedy, C T C

    2016-10-01

    Acral pseudolymphomatous angiokeratoma of children (APACHE) is a condition that was first described in 1990 in a group of children, but has since been described in adults. We present the cases of identical twin patients aged 40 years. The first brother presented with an 8-year history of itchy lesions over the left ankle and the insteps of both feet. After a diagnostic biopsy, he was treated with potent steroids under occlusion for 8 weeks, which resulted in flattening of the lesions and resolution of the pruritus. The second twin had a 20-year history of a very similar presentation but the lesions were less pronounced; he chose not to have treatment. No other family members were affected. Skin biopsies from both patients showed similar changes. Within an overall hyperkeratotic and acanthotic epidermis, there were focal areas of lichenoid change and epidermal thinning. Beneath these areas, there was oedema and nodular aggregates of dense inflammatory cell infiltrate, predominantly lymphocytic infiltrate. APACHE has not been previously described in twins. PMID:27663149

  13. Toward Understanding Suicide Among Youths: Results From the White Mountain Apache Tribally Mandated Suicide Surveillance System, 2001–2006

    PubMed Central

    Barlow, Allison; Goklish, Novalene; Larzelere-Hinton, Francene; Cwik, Mary; Craig, Mariddie; Walkup, John T.

    2009-01-01

    Objectives. We examined suicide and suicide attempt rates, patterns, and risk factors among White Mountain Apache youths (aged < 25 years) from 2001 to 2006 as the first phase of a community-based participatory research process to design and evaluate suicide prevention interventions. Methods. Apache paraprofessionals gathered data as part of a tribally mandated suicide surveillance system. We compared findings to other North American populations. Results. Between 2001 and 2006, 61% of Apache suicides occurred among youths younger than 25 years. Annual rates among those aged 15 to 24 years were highest: 128.5 per 100 000, 13 times the US all-races rate and 7 times the American Indian and Alaska Native rate. The annual suicide attempt incidence rate in this age group was 3.5%. The male-to-female ratio was 5:1 for suicide and approximately 1:1 for suicide attempts. Hanging was the most common suicide method, and third most common attempt method. The most frequently cited attempt precipitants were family or intimate partner conflict. Conclusions. An innovative tribal surveillance system identified high suicide and attempt rates and unique patterns and risk factors of suicidal behavior among Apache youths. Findings are guiding targeted suicide prevention programs. PMID:19696377

  14. Earlier application of percutaneous cardiopulmonary support rescues patients from severe cardiopulmonary failure using the APACHE III scoring system.

    PubMed

    Song, Suk-Won; Yang, Hong-Suk; Lee, Sak; Youn, Young-Nam; Yoo, Kyung-Jong

    2009-12-01

    Percutaneous cardiopulmonary support (PCPS) is a widely accepted treatment for severe cardiopulmonary failure. This system, which uses a percutaneous approach and autopriming devices, can be rapidly applied in emergency situations. We sought to identify the risk factors that could help predict in-hospital mortality, and to assess its outcomes in survivors. During a 2-yr period, 50 patients underwent PCPS for the treatment of severe cardiopulmonary failure, and of those, 22 (44%) were classified as survivors and 28 (56%) as non-survivors. We compared the 2 groups for risk factors of in-hospital mortality and to establish proper PCPS timing. Twenty patients underwent PCPS for acute myocardial infarction, 20 for severe cardiopulmonary failure after cardiac surgery, 7 for acute respiratory distress syndrome, and 3 for acute myocarditis. Multivariate analysis showed that an acute physiology, age, and chronic health evaluation (APACHE) III score >or=50 prior to PCPS was the only significant predictor of in-hospital mortality (P=0.001). Overall 18-month survival was 42.2%. Cox analysis showed patients with APACHE III scores >or=50 had a poor prognosis (P=0.001). Earlier application of PCPS, and other preemptive strategies designed to optimize high-risk patients, may improve patient outcomes. Identifying patients with high APACHE scores at the beginning of PCPS may predict in-hospital mortality. Survivors, particularly those with higher APACHE scores, may require more frequent follow-up to improve overall survival.

  15. Are cicadas (Diceroprocta apache) both a "keystone" and a "critical-link" species in lower Colorado River riparian communities?

    USGS Publications Warehouse

    Andersen, Douglas C.

    1994-01-01

    Apache cicada (Homoptera: Cicadidae: Diceroprocta apache Davis) densities were estimated to be 10 individuals/m2 within a closed-canopy stand of Fremont cottonwood (Populus fremontii) and Goodding willow (Salix gooddingii) in a revegetated site adjacent to the Colorado River near Parker, Arizona. Coupled with data drawn from the literature, I estimate that up to 1.3 cm (13 1/m2) of water may be added to the upper soil layers annually through the feeding activities of cicada nymphs. This is equivalent to 12% of the annual precipitation received in the study area. Apache cicadas may have significant effects on ecosystem functioning via effects on water transport and thus act as a critical-link species in this southwest desert riverine ecosystem. Cicadas emerged later within the cottonwood-willow stand than in relatively open saltcedar-mesquite stands; this difference in temporal dynamics would affect their availability to several insectivorous bird species and may help explain the birds' recent declines. Resource managers in this region should be sensitive to the multiple and strong effects that Apache cicadas may have on ecosystem structure and functioning.

  16. The Match between Apache Indians' Culture and Educational Practices Used in Our Schools: From Problems to Solutions

    ERIC Educational Resources Information Center

    Ingalls, Lawrence; Hammond, Helen

    2007-01-01

    This study examined cultural values and practices of Apache Indian families in regards to child rearing and how culturally responsive our schools' educational practices are with this population of individuals. Findings from this study revealed a potentially negative impact on these students' development and academic achievement. Solutions to…

  17. "A Remedy for Barbarism": Indian Schools, the Civilizing Program, and the Kiowa-Comanche-Apache Reservation, 1871-1915.

    ERIC Educational Resources Information Center

    Ellis, Clyde

    1994-01-01

    Examines schooling on the Kiowa-Comanche-Apache Reservation in southwestern Oklahoma, 1871-1915. Focuses on the difficulties of holding school on the reservation, government policies aimed at "civilizing" the Indian, the gap between policy rhetoric and reality, and ways in which Indian students resisted cultural destruction while learning English…

  18. 76 FR 47441 - Safety Zone; Apache Pier Labor Day Weekend Fireworks Display, Atlantic Ocean, Myrtle Beach, SC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-05

    ... Display, Atlantic Ocean, Myrtle Beach, SC AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary safety zone on the waters of the Atlantic Ocean in the... from Apache Pier, which is located on the Atlantic Ocean. The fireworks display is scheduled...

  19. Development of a helmet/helmet-display-unit alignment tool (HAT) for the Apache helmet and display unit

    NASA Astrophysics Data System (ADS)

    McLean, William; Statz, Jonathan; Estes, Victor; Booms, Shawn; Martin, John S.; Harding, Thomas

    2015-05-01

    Project Manager (PM) Apache Block III contacted the U.S. Army Aeromedical Research Laboratory (USAARL), Fort Rucker, Alabama, requesting assistance to evaluate and find solutions to a government-developed Helmet Display Unit (HDU) device called the Mock HDU for helmet alignment of the Apache Advanced Integrated Helmet (AAIH). The AAIH is a modified Head Gear Unit No. 56 for Personnel (HGU-56/P) to replace the current Integrated Helmet and Sighting System (IHADSS). The current flashlight-based HDU simulator for helmet/HDU alignment was no longer in production or available. Proper helmet/HDU alignment is critical to position the right eye in the small HDU eye box to obtain image alignment and full field of view (FOV). The initial approach of the PM to developing a helmet/HDU fitting device (Mock HDU) was to duplicate the optical characteristics of the current tactical HDU using less complex optics. However, the results produced questionable alignment, FOV, and distortion issues, with cost and development time overruns. After evaluating the Mock HDU, USAARL proposed a cost effective, less complex optical design called the Helmet/HDU Alignment Tool (HAT). This paper will show the development, components, and evaluations of the HAT compared to the current flashlight HDU simulator device. The laboratory evaluations included FOV measurements and alignment accuracies compared to tactical HDUs. The Apache helmet fitter technicians and Apache pilots compared the HAT to the current flashlight based HDU and ranked the HAT superior.

  20. Geologic map and digital database of the Apache Canyon 7.5' quadrangle, Ventura and Kern counties, California

    USGS Publications Warehouse

    Stone, Paul; Cossette, P.M.

    2000-01-01

    The Apache Canyon 7.5-minute quadrangle is located in southwestern California about 55 km northeast of Santa Barbara and 65 km southwest of Bakersfield. This report presents the results of a geologic mapping investigation of the Apache Canyon quadrangle that was carried out in 1997-1999 as part of the U.S. Geological Survey's Southern California Areal Mapping Project. This quadrangle was chosen for study because it is in an area of complex, incompletely understood Cenozoic stratigraphy and structure of potential importance for regional tectonic interpretations, particularly those involving the San Andreas fault located just northwest of the quadrangle and the Big Pine fault about 10 km to the south. In addition, the quadrangle is notable for its well-exposed sequences of folded Neogene nonmarine strata including the Caliente Formation of Miocene age from which previous workers have collected and described several biostratigraphically significant land-mammal fossil assemblages. During the present study, these strata were mapped in detail throughout the quadrangle to provide an improved framework for possible future paleontologic investigations. The Apache Canyon quadrangle is in the eastern part of the Cuyama 30-minute by 60-minute quadrangle and is largely part of an erosionally dissected terrain known as the Cuyama badlands at the east end of Cuyama Valley. Most of the Apache Canyon quadrangle consists of public lands in the Los Padres National Forest.

  1. Ground-water exploration in the Bosque del Apache Grant, Socorro County, New Mexico

    USGS Publications Warehouse

    Cooper, James B.

    1968-01-01

    Test drilling along the Rio Grande in the Bosque del Apache Grant in Socorro County, New Mexico has shown that the area is hydrologically complex and that the quality of the ground water varies from saline to fresh within short distances both laterally and vertically. Nearly all of the riverside land in the Grant is occupied by the migratory waterfowl refuge of the Bosque del Apache National Wildlife Refuge. Potable and near-potable water is obtained from 12 wells in this area that tap sand and gravel, and the wells are capable of yielding 1,000 gallons per minute or more. Stallion Range Center, a military installation on the White Sands Missile Range, about 15 miles east of =he waterfowl refuge, needs about 100,000 gallons per day of potable water. Potable water in large quantities is not known to be available at a location closer to the Center than the refuge area. The Fish and Wildlife Service, which operates the waterfowl refuge, gave permission to White Sands Missile Range to test drill and to develop a supply well in certain areas along the Rio Grande outside the managed lands of the refuge. The U.S. Geological Survey was then asked by White Sands Missile Range to choose locations for test drilling and to monitor drilling and testing of the wells. Between 1963 and 1967 test wells were drilled and a suitable location for a supply well as found. The well would be about 250 feet deep and would tap a body of potable water that is about 100 feet in thickness and is thought to underlie an area of at least 5 square miles. This report contains diagrammatic sections that show the lateral and vertical relation of waters of different quality along the Rio Grande in a part of the Bosque del Apache Grant. Basic data are given in tables; they include records of 7 test wells and 12 high-yield supply wells, and 52 chemical analyses of ground water from the wells.

  2. Constructing Flexible, Configurable, ETL Pipelines for the Analysis of "Big Data" with Apache OODT

    NASA Astrophysics Data System (ADS)

    Hart, A. F.; Mattmann, C. A.; Ramirez, P.; Verma, R.; Zimdars, P. A.; Park, S.; Estrada, A.; Sumarlidason, A.; Gil, Y.; Ratnakar, V.; Krum, D.; Phan, T.; Meena, A.

    2013-12-01

    A plethora of open source technologies for manipulating, transforming, querying, and visualizing 'big data' have blossomed and matured in the last few years, driven in large part by recognition of the tremendous value that can be derived by leveraging data mining and visualization techniques on large data sets. One facet of many of these tools is that input data must often be prepared into a particular format (e.g.: JSON, CSV), or loaded into a particular storage technology (e.g.: HDFS) before analysis can take place. This process, commonly known as Extract-Transform-Load, or ETL, often involves multiple well-defined steps that must be executed in a particular order, and the approach taken for a particular data set is generally sensitive to the quantity and quality of the input data, as well as the structure and complexity of the desired output. When working with very large, heterogeneous, unstructured or semi-structured data sets, automating the ETL process and monitoring its progress becomes increasingly important. Apache Object Oriented Data Technology (OODT) provides a suite of complementary data management components called the Process Control System (PCS) that can be connected together to form flexible ETL pipelines as well as browser-based user interfaces for monitoring and control of ongoing operations. The lightweight, metadata driven middleware layer can be wrapped around custom ETL workflow steps, which themselves can be implemented in any language. Once configured, it facilitates communication between workflow steps and supports execution of ETL pipelines across a distributed cluster of compute resources. As participants in a DARPA-funded effort to develop open source tools for large-scale data analysis, we utilized Apache OODT to rapidly construct custom ETL pipelines for a variety of very large data sets to prepare them for analysis and visualization applications. We feel that OODT, which is free and open source software available through the Apache

  3. SAPS 3, APACHE IV or GRACE: which score to choose for acute coronary syndrome patients in intensive care units?

    PubMed

    Nassar Junior, Antonio Paulo; Mocelin, Amilcar Oshiro; Andrade, Fabio Moreira; Brauer, Leonardo; Giannini, Fabio Poianas; Nunes, Andre Luiz Baptiston; Dias, Carlos Augusto

    2013-01-01

    CONTEXT AND OBJECTIVE Acute coronary syndromes (ACS) are a common cause of intensive care unit (ICU) admission. Specific prognostic scores have been developed and validated for ACS patients and, among them, GRACE (Global Registry of Acute Coronary Events) has had the best performance. However, intensive care clinicians generally use prognostic scores developed from heterogeneous populations of critically ill patients, such as APACHE IV (Acute Physiologic and Chronic Health Evaluation IV) and SAPS 3 (Simplified Acute Physiology Score 3). The aim of this study was to evaluate and compare the performance of these three scores in a non-selected population of ACS cases. DESIGN AND SETTING Retrospective observational study to evaluate three prognostic scores in a population of ACS patients admitted to three general ICUs in private hospitals in São Paulo. METHODS All patients with ACS admitted from July 2008 to December 2009 were considered for inclusion in the study. Score calibration and discrimination were evaluated in relation to predicting hospital mortality. RESULTS A total of 1065 patients were included. The calibration was appropriate for APACHE IV and GRACE but not for SAPS 3. The discrimination was very good for all scores (area under curve of 0.862 for GRACE, 0.860 for APACHE IV and 0.804 for SAPS 3). CONCLUSIONS In this population of ACS patients admitted to ICUs, GRACE and APACHE IV were adequately calibrated, but SAPS 3 was not. All three scores had very good discrimination. GRACE and APACHE IV may be used for predicting mortality risk among ACS patients.

  4. Unsaturated fractured rock characterization methods and data sets at the Apache Leap Tuff Site

    SciTech Connect

    Rasmussen, T.C.; Evans, D.D.; Sheets, P.J.; Blanford, J.H.

    1990-08-01

    Performance assessment of high-level nuclear waste containment feasibility requires representative values of parameters as input, including parameter moments, distributional characteristics, and covariance structures between parameters. To meet this need, characterization methods and data sets for interstitial, hydraulic, pneumatic and thermal parameters for a slightly welded fractured tuff at the Apache Leap Tuff Site situated in central Arizona are reported in this document. The data sets include the influence of matric suction on measured parameters. Spatial variability is investigated by sampling along nine boreholes at regular distances. Laboratory parameter estimates for 105 core segments are provided, as well as field estimates centered on the intervals where the core segments were collected. Measurement uncertainty is estimated by repetitively testing control samples. 31 refs., 10 figs., 21 tabs.

  5. Outcrop Analysis of the Cretaceous Mesaverde Group: Jicarilla Apache Reservation, New Mexico

    SciTech Connect

    Ridgley, Jennie; Dunbar, Robin Wright

    2001-04-24

    Field work for this project was conducted during July and April 1998, at which time fourteen measured sections were described and correlated on or adjacent to Jicarilla Apache Reservation lands. A fifteenth section, described east of the main field area, is included in this report, although its distant location precluded use in the correlations and cross sections presented herein. Ground-based photo mosaics were shot for much of the exposed Mesaverde outcrop belt and were used to assist in correlation. Outcrop gamma-ray surveys at six of the fifteen measured sections using a GAD-6 scintillometer was conducted. The raw gamma-ray data are included in this report, however, analysis of those data is part of the ongoing Phase Two of this project.

  6. Extraction of UMLS® Concepts Using Apache cTAKES™ for German Language.

    PubMed

    Becker, Matthias; Böckmann, Britta

    2016-01-01

    Automatic information extraction of medical concepts and classification with semantic standards from medical reports is useful for standardization and for clinical research. This paper presents an approach for an UMLS concept extraction with a customized natural language processing pipeline for German clinical notes using Apache cTAKES. The objectives are, to test the natural language processing tool for German language if it is suitable to identify UMLS concepts and map these with SNOMED-CT. The German UMLS database and German OpenNLP models extended the natural language processing pipeline, so the pipeline can normalize to domain ontologies such as SNOMED-CT using the German concepts. For testing, the ShARe/CLEF eHealth 2013 training dataset translated into German was used. The implemented algorithms are tested with a set of 199 German reports, obtaining a result of average 0.36 F1 measure without German stemming, pre- and post-processing of the reports.

  7. Inequalities in Open Source Software Development: Analysis of Contributor's Commits in Apache Software Foundation Projects.

    PubMed

    Chełkowski, Tadeusz; Gloor, Peter; Jemielniak, Dariusz

    2016-01-01

    While researchers are becoming increasingly interested in studying OSS phenomenon, there is still a small number of studies analyzing larger samples of projects investigating the structure of activities among OSS developers. The significant amount of information that has been gathered in the publicly available open-source software repositories and mailing-list archives offers an opportunity to analyze projects structures and participant involvement. In this article, using on commits data from 263 Apache projects repositories (nearly all), we show that although OSS development is often described as collaborative, but it in fact predominantly relies on radically solitary input and individual, non-collaborative contributions. We also show, in the first published study of this magnitude, that the engagement of contributors is based on a power-law distribution. PMID:27096157

  8. Next Generation Astronomical Data Processing using Big Data Technologies from the Apache Software Foundation

    NASA Astrophysics Data System (ADS)

    Mattmann, Chris

    2014-04-01

    In this era of exascale instruments for astronomy we must naturally develop next generation capabilities for the unprecedented data volume and velocity that will arrive due to the veracity of these ground-based sensor and observatories. Integrating scientific algorithms stewarded by scientific groups unobtrusively and rapidly; intelligently selecting data movement technologies; making use of cloud computing for storage and processing; and automatically extracting text and metadata and science from any type of file are all needed capabilities in this exciting time. Our group at NASA JPL has promoted the use of open source data management technologies available from the Apache Software Foundation (ASF) in pursuit of constructing next generation data management and processing systems for astronomical instruments including the Expanded Very Large Array (EVLA) in Socorro, NM and the Atacama Large Milimetre/Sub Milimetre Array (ALMA); as well as for the KAT-7 project led by SKA South Africa as a precursor to the full MeerKAT telescope. In addition we are funded currently by the National Science Foundation in the US to work with MIT Haystack Observatory and the University of Cambridge in the UK to construct a Radio Array of Portable Interferometric Devices (RAPID) that will undoubtedly draw from the rich technology advances underway. NASA JPL is investing in a strategic initiative for Big Data that is pulling in these capabilities and technologies for astronomical instruments and also for Earth science remote sensing. In this talk I will describe the above collaborative efforts underway and point to solutions in open source from the Apache Software Foundation that can be deployed and used today and that are already bringing our teams and projects benefits. I will describe how others can take advantage of our experience and point towards future application and contribution of these tools.

  9. Update on Astrometric Follow-Up at Apache Point Observatory by Adler Planetarium

    NASA Astrophysics Data System (ADS)

    Nault, Kristie A.; Brucker, Melissa; Hammergren, Mark

    2016-10-01

    We began our NEO astrometric follow-up and characterization program in 2014 Q4 using about 500 hours of observing time per year with the Astrophysical Research Consortium (ARC) 3.5m telescope at Apache Point Observatory (APO). Our observing is split into 2 hour blocks approximately every other night for astrometry (this poster) and several half-nights per month for spectroscopy (see poster by M. Hammergren et al.) and light curve studies.For astrometry, we use the ARC Telescope Imaging Camera (ARCTIC) with an SDSS r filter, in 2 hour observing blocks centered around midnight. ARCTIC has a magnitude limit of V~23 in 60s, and we target 20 NEOs per session. ARCTIC has a FOV 1.57 times larger and a readout time half as long as the previous imager, SPIcam, which we used from 2014 Q4 through 2015 Q3. Targets are selected primarily from the Minor Planet Center's (MPC) NEO Confirmation Page (NEOCP), and NEA Observation Planning Aid; we also refer to JPL's What's Observable page, the Spaceguard Priority List and Faint NEOs List, and requests from other observers. To quickly adapt to changing weather and seeing conditions, we create faint, midrange, and bright target lists. Detected NEOs are measured with Astrometrica and internal software, and the astrometry is reported to the MPC.As of June 19, 2016, we have targeted 2264 NEOs, 1955 with provisional designations, 1582 of which were detected. We began observing NEOCP asteroids on January 30, 2016, and have targeted 309, 207 of which were detected. In addition, we serendipitously observed 281 moving objects, 201 of which were identified as previously known objects.This work is based on observations obtained with the Apache Point Observatory 3.5m telescope, which is owned and operated by the Astrophysical Research Consortium. We gratefully acknowledge support from NASA NEOO award NNX14AL17G and thank the University of Chicago Department of Astronomy and Astrophysics for observing time in 2014.

  10. Precise Gravity Measurements for Lunar Laser Ranging at Apache Point Observatory

    NASA Astrophysics Data System (ADS)

    Crossley, D. J.; Murphy, T.; Boy, J.; De Linage, C.; Wheeler, R. D.; Krauterbluth, K.

    2012-12-01

    Lunar Laser Ranging (LLR) at Apache Point Observatory began in 2006 under the APOLLO project using a 3.5 m telescope on a 2780 m summit in New Mexico. Recent improvements in the technical operations are producing uncertainties at the few-mm level in the 1.5 x 10^13 cm separation of the solar orbits of the Earth and Moon. This level of sensitivity permits a number of important aspects of gravitational theory to be tested. Among these is the Equivalence Principle that determines the universality of free fall, tests of the time variation of the Gravitational Constant G, deviations from the inverse square law, and preferred frame effects. In 2009 APOLLO installed a superconducting gravimeter (SG) on the concrete pier under the main telescope to further constrain the deformation of the site as part of an initiative to improve all aspects of the modeling process. We have analyzed more than 3 years of high quality SG data that provides unmatched accuracy in determining the local tidal gravimetric factors for the solid Earth and ocean tide loading. With on-site gravity we have direct measurements of signals such as polar motion, and can compute global atmospheric and hydrological loading for the site using GLDAS and local hydrology models that are compared with the SG observations. We also compare the SG residuals with satellite estimates of seasonal ground gravity variations from the GRACE mission. Apache Point is visited regularly by a team from the National Geospatial-Intelligence Agency to provide absolute gravity values for the calibration of the SG and to determine secular gravity changes. Nearby GPS location P027 provides continuous position information from the Plate Boundary Observatory of Earthscope that is used to correlate gravity/height variations at the site. Unusual aspects of the data processing include corrections for the telescope azimuth that appear as small offsets at the 1 μGal level and can be removed by correlating the azimuth data with the SG

  11. Visible Wavelength Reflectance Spectra and Taxonomies of Near-Earth Objects from Apache Point Observatory

    NASA Astrophysics Data System (ADS)

    Hammergren, Mark; Brucker, Melissa J.; Nault, Kristie A.; Gyuk, Geza; Solontoi, Michael R.

    2015-11-01

    Near-Earth Objects (NEOs) are interesting to scientists and the general public for diverse reasons: their impacts pose a threat to life and property; they present important albeit biased records of the formation and evolution of the Solar System; and their materials may provide in situ resources for future space exploration and habitation.In January 2015 we began a program of NEO astrometric follow-up and physical characterization using a 17% share of time on the Astrophysical Research Consortium (ARC) 3.5-meter telescope at Apache Point Observatory (APO). Our 500 hours of annual observing time are split into frequent, short astrometric runs (see poster by K. A. Nault et. al), and half-night runs devoted to physical characterization (see poster by M. J. Brucker et. al for preliminary rotational lightcurve results). NEO surface compositions are investigated with 0.36-1.0 μm reflectance spectroscopy using the Dual Imaging Spectrograph (DIS) instrument. As of August 25, 2015, including testing runs during fourth quarter 2014, we have obtained reflectance spectra of 68 unique NEOs, ranging in diameter from approximately 5m to 8km.In addition to investigating the compositions of individual NEOs to inform impact hazard and space resource evaluations, we may examine the distribution of taxonomic types and potential trends with other physical and orbital properties. For example, the Yarkovsky effect, which is dependent on asteroid shape, mass, rotation, and thermal characteristics, is believed to dominate other dynamical effects in driving the delivery of small NEOs from the main asteroid belt. Studies of the taxonomic distribution of a large sample of NEOs of a wide range of sizes will test this hypothesis.We present a preliminary analysis of the reflectance spectra obtained in our survey to date, including taxonomic classifications and potential trends with size.Acknowledgements: Based on observations obtained with the Apache Point Observatory 3.5-meter telescope, which

  12. Building a Snow Data System on the Apache OODT Open Technology Stack

    NASA Astrophysics Data System (ADS)

    Goodale, C. E.; Painter, T. H.; Mattmann, C. A.; Hart, A. F.; Ramirez, P.; Zimdars, P.; Bryant, A. C.; Snow Data System Team

    2011-12-01

    Snow cover and its melt dominate regional climate and hydrology in many of the world's mountainous regions. One-sixth of Earth's population depends on snow- or glacier-melt for water resources. Operationally, seasonal forecasts of snowmelt-generated streamflow are leveraged through empirical relations based on past snowmelt periods. These historical data show that climate is changing, but the changes reduce the reliability of the empirical relations. Therefore optimal future management of snowmelt derived water resources will require explicit physical models driven by remotely sensed snow property data. Toward this goal, the Snow Optics Laboratory at the Jet Propulsion Laboratory has initiated a near real-time processing pipeline to generate and publish post-processed snow data products within a few hours of satellite acquisition. To solve this challenge, a Scientific Data Management and Processing System was required and the JPL Team leveraged an open-source project called Object Oriented Data Technology (OODT). OODT was developed within NASA's Jet Propulsion Laboratory across the last 10 years. OODT has supported various scientific data management and processing projects, providing solutions in the Earth, Planetary, and Medical science fields. It became apparent that the project needed to be opened to a larger audience to foster and promote growth and adoption. OODT was open-sourced at the Apache Software Foundation in November 2010 and has a growing community of users and committers that are constantly improving the software. Leveraging OODT, the JPL Snow Data System (SnowDS) Team was able to install and configure a core Data Management System (DMS) that would download MODIS raw data files and archive the products in a local repository for post processing. The team has since built an online data portal, and an algorithm-processing pipeline using the Apache OODT software as the foundation. We will present the working SnowDS system with its core remote sensing

  13. Visual issues associated with the use of the integrated helmet and display sighting system (IHADSS) in the Apache helicopter: three decades in review

    NASA Astrophysics Data System (ADS)

    Hiatt, Keith L.; Rash, Clarence E.; Heinecke, Kevin

    2008-04-01

    In the late 1970s the U.S. Army developed the Integrated Helmet and Display Sighting System (IHADSS), which is a helmet-mounted display (HMD) for use in the AH-64 Apache helicopter. The helicopter and the system were designed with the Cold War in mind such that the Apache would be able to stand off far from the frontlines and attack deep target-primarily tanks-before they could engage our ground forces. The design used a right-sided monocular display optical system that was intended to reduce head-supported weight. This novel monocular design introduced a number of issues that had the potential of causing visual perception problems for pilots. Since the initial fielding of the Apache in the early 1980s, numerous reports have appeared in the literature that evaluated realized visual complaints voiced by Apache aircrew. In this review, the authors provide a summary of seminal reports, surveys, and experiments conducted over the past three decades. The extant literature described investigated these visual issues as the Apache's mission has evolved from the stand-off engagement tactics of the Cold War to the new Apache missions of close air support, deep attack, and raids currently occurring in the Global War on Terrorism.

  14. Spatial correlations of Diceroprocta apache and its host plants: Evidence for a negative impact from Tamarix invasion

    USGS Publications Warehouse

    Ellingson, A.R.; Andersen, D.C.

    2002-01-01

    1. The hypothesis that the habitat-scale spatial distribution of the, Apache cicada Diceroprocta apache Davis is unaffected by the presence of the invasive exotic saltcedar Tamarix ramosissima was tested using data from 205 1-m2 quadrats placed within the flood-plain of the Bill Williams River, Arizona, U.S.A. Spatial dependencies within and between cicada density and habitat variables were estimated using Moran's I and its bivariate analogue to discern patterns and associations at spatial scales from 1 to 30 m. 2. Apache cicadas were spatially aggregated in high-density clusters averaging 3m in diameter. A positive association between cicada density, estimated by exuvial density, and the per cent canopy cover of a native tree, Goodding's willow Salix gooddingii, was detected in a non-spatial correlation analysis. No non-spatial association between cicada density and saltcedar canopy cover was detected. 3. Tests for spatial cross-correlation using the bivariate IYZ indicated the presence of a broad-scale negative association between cicada density and saltcedar canopy cover. This result suggests that large continuous stands of saltcedar are associated with reduced cicada density. In contrast, positive associations detected at spatial scales larger than individual quadrats suggested a spill-over of high cicada density from areas featuring Goodding's willow canopy into surrounding saltcedar monoculture. 4. Taken together and considered in light of the Apache cicada's polyphagous habits, the observed spatial patterns suggest that broad-scale factors such as canopy heterogeneity affect cicada habitat use more than host plant selection. This has implications for management of lower Colorado River riparian woodlands to promote cicada presence and density through maintenance or creation of stands of native trees as well as manipulation of the characteristically dense and homogeneous saltcedar canopies.

  15. Historical review of uranium-vanadium in the eastern Carrizo Mountains, San Juan County, New Mexico and Apache County, Arizona

    SciTech Connect

    Chenoweth, W.L.

    1980-03-01

    This report is a brief review of the uranium and/or vanadium mining in the eastern Carrizo Mountains, San Juan County, New Mexico and Apache County, Arizona. It was prepared at the request of the Navajo Tribe, the New Mexico Energy and Minerals Department, and the Arizona Bureau of Geology and Mineral Technology. This report deals only with historical production data. The locations of the mines and the production are presented in figures and tables.

  16. THE DATA REDUCTION PIPELINE FOR THE APACHE POINT OBSERVATORY GALACTIC EVOLUTION EXPERIMENT

    SciTech Connect

    Nidever, David L.; Holtzman, Jon A.; Prieto, Carlos Allende; Mészáros, Szabolcs; Bender, Chad; Desphande, Rohit; Bizyaev, Dmitry; Burton, Adam; García Pérez, Ana E.; Hearty, Fred R.; Majewski, Steven R.; Skrutskie, Michael F.; Sobeck, Jennifer S.; Wilson, John C.; Fleming, Scott W.; Muna, Demitri; Nguyen, Duy; Schiavon, Ricardo P.; Shetrone, Matthew

    2015-12-15

    The Apache Point Observatory Galactic Evolution Experiment (APOGEE), part of the Sloan Digital Sky Survey III, explores the stellar populations of the Milky Way using the Sloan 2.5-m telescope linked to a high resolution (R ∼ 22,500), near-infrared (1.51–1.70 μm) spectrograph with 300 optical fibers. For over 150,000 predominantly red giant branch stars that APOGEE targeted across the Galactic bulge, disks and halo, the collected high signal-to-noise ratio (>100 per half-resolution element) spectra provide accurate (∼0.1 km s{sup −1}) RVs, stellar atmospheric parameters, and precise (≲0.1 dex) chemical abundances for about 15 chemical species. Here we describe the basic APOGEE data reduction software that reduces multiple 3D raw data cubes into calibrated, well-sampled, combined 1D spectra, as implemented for the SDSS-III/APOGEE data releases (DR10, DR11 and DR12). The processing of the near-IR spectral data of APOGEE presents some challenges for reduction, including automated sky subtraction and telluric correction over a 3°-diameter field and the combination of spectrally dithered spectra. We also discuss areas for future improvement.

  17. Visible Wavelength Reflectance Spectra of Near-Earth Objects from Apache Point Observatory: Science Highlights

    NASA Astrophysics Data System (ADS)

    Hammergren, Mark; Brucker, Melissa; Nault, Kristie A.; Gyuk, Geza

    2016-10-01

    In January 2015 we began a program of near-Earth object (NEO) astrometric follow-up and physical characterization using a 17% share of time on the Astrophysical Research Consortium (ARC) 3.5-meter telescope at Apache Point Observatory (APO). Our roughly 500 hours of annual observing time are split into 2 hour runs usually in the middle of every other night (see poster by K. Nault et al.), and frequent half-night runs devoted to physical characterization (this poster). NEO surface compositions are investigated with 0.36-1.0 μm reflectance spectroscopy using the Dual Imaging Spectrograph instrument. As of June 22, 2016 we have obtained reflectance spectra of 129 unique NEOs, ranging in diameter from approximately 5 m to 6 km.Highlights of this work presented here include 106 spectra of (357439) 2004 BL86 spanning 3 hours 4.5 minutes, more than a full rotation, and spectra of 18 objects with diameters comparable to historical Earth impactors (e.g., Tunguska, Chelyabinsk and smaller bolides).This work is based on observations obtained with the APO 3.5-meter telescope, which is owned and operated by ARC. We gratefully acknowledge support from NASA NEOO award NNX14AL17G, and thank the University of Chicago Department of Astronomy and Astrophysics for observing time in 2014.

  18. The Apache Point Observatory Galactic Evolution Experiment (APOGEE) and its successor, APOGEE-2

    NASA Astrophysics Data System (ADS)

    Majewski, S. R.; APOGEE Team; APOGEE-2 Team

    2016-09-01

    The Apache Point Observatory Galactic Evolution Experiment (APOGEE) of Sloan Digital Sky Survey III (SDSS-III) has produced a large catalog of high resolution ({R = 22 500}), high quality (S/N > 100), infrared (H-band) spectra for stars throughout all stellar populations of the Milky Way, including in regions veiled by significant dust opacity. APOGEE's half million spectra collected on > 163 000 unique stars, with time series information via repeat visits to each star, are being applied to numerous problems in stellar populations, Galactic astronomy, and stellar astrophysics. From among the early results of the APOGEE project - which span from measurements of Galactic dynamics, to multi-element chemical maps of the disk and bulge, new views of the interstellar medium, explorations of stellar companions, the chemistry of star clusters, and the discovery of rare stellar species - I highlight a few results that demonstrate APOGEE's unique ability to sample and characterize the Galactic disk and bulge. Plans are now under way for an even more ambitious successor to APOGEE: the six-year, dual-hemisphere APOGEE-2 project. Both phases of APOGEE feature a strong focus on targets having asteroseismological measurements from either Kepler or {CoRoT}, from which it is possible to derive relatively precise stellar ages. The combined APOGEE and APOGEE-2 databases of stellar chemistry, dynamics and ages constitute an unusually comprehensive, systematic and homogeneous resource for constraining models of Galactic evolution.

  19. The Data Reduction Pipeline for the Apache Point Observatory Galactic Evolution Experiment

    NASA Astrophysics Data System (ADS)

    Nidever, David L.; Holtzman, Jon A.; Allende Prieto, Carlos; Beland, Stephane; Bender, Chad; Bizyaev, Dmitry; Burton, Adam; Desphande, Rohit; Fleming, Scott W.; García Pérez, Ana E.; Hearty, Fred R.; Majewski, Steven R.; Mészáros, Szabolcs; Muna, Demitri; Nguyen, Duy; Schiavon, Ricardo P.; Shetrone, Matthew; Skrutskie, Michael F.; Sobeck, Jennifer S.; Wilson, John C.

    2015-12-01

    The Apache Point Observatory Galactic Evolution Experiment (APOGEE), part of the Sloan Digital Sky Survey III, explores the stellar populations of the Milky Way using the Sloan 2.5-m telescope linked to a high resolution (R ˜ 22,500), near-infrared (1.51-1.70 μm) spectrograph with 300 optical fibers. For over 150,000 predominantly red giant branch stars that APOGEE targeted across the Galactic bulge, disks and halo, the collected high signal-to-noise ratio (>100 per half-resolution element) spectra provide accurate (˜0.1 km s-1) RVs, stellar atmospheric parameters, and precise (≲0.1 dex) chemical abundances for about 15 chemical species. Here we describe the basic APOGEE data reduction software that reduces multiple 3D raw data cubes into calibrated, well-sampled, combined 1D spectra, as implemented for the SDSS-III/APOGEE data releases (DR10, DR11 and DR12). The processing of the near-IR spectral data of APOGEE presents some challenges for reduction, including automated sky subtraction and telluric correction over a 3°-diameter field and the combination of spectrally dithered spectra. We also discuss areas for future improvement.

  20. Integrating the Apache Big Data Stack with HPC for Big Data

    NASA Astrophysics Data System (ADS)

    Fox, G. C.; Qiu, J.; Jha, S.

    2014-12-01

    There is perhaps a broad consensus as to important issues in practical parallel computing as applied to large scale simulations; this is reflected in supercomputer architectures, algorithms, libraries, languages, compilers and best practice for application development. However, the same is not so true for data intensive computing, even though commercially clouds devote much more resources to data analytics than supercomputers devote to simulations. We look at a sample of over 50 big data applications to identify characteristics of data intensive applications and to deduce needed runtime and architectures. We suggest a big data version of the famous Berkeley dwarfs and NAS parallel benchmarks and use these to identify a few key classes of hardware/software architectures. Our analysis builds on combining HPC and ABDS the Apache big data software stack that is well used in modern cloud computing. Initial results on clouds and HPC systems are encouraging. We propose the development of SPIDAL - Scalable Parallel Interoperable Data Analytics Library -- built on system aand data abstractions suggested by the HPC-ABDS architecture. We discuss how it can be used in several application areas including Polar Science.

  1. Target Selection for the Apache Point Observatory Galactic Evolution Experiment (APOGEE)

    NASA Astrophysics Data System (ADS)

    Zasowski, G.; Johnson, Jennifer A.; Frinchaboy, P. M.; Majewski, S. R.; Nidever, D. L.; Rocha Pinto, H. J.; Girardi, L.; Andrews, B.; Chojnowski, S. D.; Cudworth, K. M.; Jackson, K.; Munn, J.; Skrutskie, M. F.; Beaton, R. L.; Blake, C. H.; Covey, K.; Deshpande, R.; Epstein, C.; Fabbian, D.; Fleming, S. W.; Garcia Hernandez, D. A.; Herrero, A.; Mahadevan, S.; Mészáros, Sz.; Schultheis, M.; Sellgren, K.; Terrien, R.; van Saders, J.; Allende Prieto, C.; Bizyaev, D.; Burton, A.; Cunha, K.; da Costa, L. N.; Hasselquist, S.; Hearty, F.; Holtzman, J.; García Pérez, A. E.; Maia, M. A. G.; O'Connell, R. W.; O'Donnell, C.; Pinsonneault, M.; Santiago, B. X.; Schiavon, R. P.; Shetrone, M.; Smith, V.; Wilson, J. C.

    2013-10-01

    The Apache Point Observatory Galactic Evolution Experiment (APOGEE) is a high-resolution infrared spectroscopic survey spanning all Galactic environments (i.e., bulge, disk, and halo), with the principal goal of constraining dynamical and chemical evolution models of the Milky Way. APOGEE takes advantage of the reduced effects of extinction at infrared wavelengths to observe the inner Galaxy and bulge at an unprecedented level of detail. The survey's broad spatial and wavelength coverage enables users of APOGEE data to address numerous Galactic structure and stellar populations issues. In this paper we describe the APOGEE targeting scheme and document its various target classes to provide the necessary background and reference information to analyze samples of APOGEE data with awareness of the imposed selection criteria and resulting sample properties. APOGEE's primary sample consists of ~105 red giant stars, selected to minimize observational biases in age and metallicity. We present the methodology and considerations that drive the selection of this sample and evaluate the accuracy, efficiency, and caveats of the selection and sampling algorithms. We also describe additional target classes that contribute to the APOGEE sample, including numerous ancillary science programs, and we outline the targeting data that will be included in the public data releases.

  2. FEASIBILITY STUDY FOR A PETROLEUM REFINERY FOR THE JICARILLA APACHE TRIBE

    SciTech Connect

    John D. Jones

    2004-10-01

    A feasibility study for a proposed petroleum refinery for the Jicarilla Apache Indian Reservation was performed. The available crude oil production was identified and characterized. There is 6,000 barrels per day of crude oil production available for processing in the proposed refinery. The proposed refinery will utilize a lower temperature, smaller crude fractionation unit. It will have a Naphtha Hydrodesulfurizer and Reformer to produce high octane gasoline. The surplus hydrogen from the reformer will be used in a specialized hydrocracker to convert the heavier crude oil fractions to ultra low sulfur gasoline and diesel fuel products. The proposed refinery will produce gasoline, jet fuel, diesel fuel, and a minimal amount of lube oil. The refinery will require about $86,700,000 to construct. It will have net annual pre-tax profit of about $17,000,000. The estimated return on investment is 20%. The feasibility is positive subject to confirmation of long term crude supply. The study also identified procedures for evaluating processing options as a means for American Indian Tribes and Native American Corporations to maximize the value of their crude oil production.

  3. Improvements to the Apache Point 3.5-m primary-mirror support system

    NASA Astrophysics Data System (ADS)

    Brown, Yorke J.; Davis, Jon E.

    1998-05-01

    The primary mirror of the Apache Point 3.5 meter telescope rests on an array of small pneumatic actuators distributed over the back plate of the mirror and within its honey comb cells. A control system constantly adjusts the pressure in the actuators so as to synthesize a perfectly rigid mounting, thus maintaining both the figure of the mirror and its orientation with respect to the mirror cell. In its original configuration, the APO 3.5 meter system exhibited a number of anomalous behaviors that detracted from the optical performance of the telescope. Analysis of the design indicated three basic problems: first that the pneumatic servovalves suffered from mechanical nonlinearities and an adverse dependence of their transfer function on operating pressure; second, that the air supply system could not exhaust air from the actuators rapidly enough near the horizon and zenith; and third, that the control system did not adequately account for the inertia of the mirror under dynamic conditions. Consequently, we have designed and installed a new control system which addresses these deficiencies. The new system employs high-bandwidth, flapper-type proportional valves that eliminate the mechanical problems and permit implementation of a high- performance controller. The new controller utilizes the existing hard points for mirror position sensing, but implements a pressure-feedback inner loop and a more sophisticated dynamic model. The air supply system now incorporates a sub-atmospheric return and operates closed- loop to minimize contamination problems. The new system exhibits substantial improvements over its previous performance, with positioning errors in the sub-micron range. The design has been selected for use on the Sloan Digital Sky Survey telescope.

  4. Field studies at the Apache Leap Research Site in support of alternative conceptual models

    SciTech Connect

    Woodhouse, E.G.; Davidson, G.R.; Theis, C.

    1997-08-01

    This is a final technical report for a project of the U.S Nuclear Regulatory Commission (sponsored contract NRC-04-090-51) with the University of Arizona. The contract was an optional extension that was initiated on July 21, 1994 and that expired on May 31, 1995. The project manager was Thomas J. Nicholson, Office of Nuclear Regulatory Research. The objectives of this contract were to examine hypotheses and conceptual models concerning unsaturated flow and transport through fractured rock, and to design and execute confirmatory field and laboratory experiments to test these hypotheses and conceptual models at the Apache Leap Research Site near Superior, Arizona. The results discussed here are products of specific tasks that address a broad spectrum of issues related to flow and transport through fractures. Each chapter in this final report summarizes research related to a specific set of objectives and can be read and interpreted as a separate entity. The tasks include detection and characterization of historical rapid fluid flow through fractured rock and the relationship to perched water systems using environmental isotopic tracers of {sup 3}H and {sup 14}C, fluid- and rock-derived {sup 2343}U/{sup 238}U measurements, and geophysical data. The water balance in a small watershed at the ALRS demonstrates the methods of acounting for ET, and estimating the quantity of water available for infiltration through fracture networks. Grain density measurements were made for core-sized samples using a newly designed gas pycnometer. The distribution and magnitude of air permeability measurements have been measured in a three-dimensional setting; the subsequent geostatistical analysis is presented. Electronic versions of the data presented here are available from authors; more detailed discussions and analyses are available in technical publications referenced herein, or soon to appear in the professional literature.

  5. Mescalero Apache Tribe Monitored Retrievable Storage (MRS). Phase 1 feasibility study report

    SciTech Connect

    Peso, F.

    1992-03-13

    The Nuclear Waste Policy Act of 1982, as amended, authorizes the siting, construction and operation of a Monitored Retrievable Storage (MRS) facility. The MRS is intended to be used for the temporary storage of spent nuclear fuel from the nation`s nuclear power plants beginning as early as 1998. Pursuant to the Nuclear Waste Policy Act, the Office of the Nuclear Waste Negotiator was created. On October 7, 1991, the Nuclear Waste Negotiator invited the governors of states and the Presidents of Indian tribes to apply for government grants in order to conduct a study to assess under what conditions, if any, they might consider hosting an MRS facility. Pursuant to this invitation, on October 11, 1991 the Mescalero Apache Indian Tribe of Mescalero, NM applied for a grant to conduct a phased, preliminary study of the safety, technical, political, environmental, social and economic feasibility of hosting an MRS. The preliminary study included: (1) An investigative education process to facilitate the Tribe`s comprehensive understanding of the safety, environmental, technical, social, political, and economic aspects of hosting an MRS, and; (2) The development of an extensive program that is enabling the Tribe, in collaboration with the Negotiator, to reach an informed and carefully researched decision regarding the conditions, (if any), under which further pursuit of the MRS would be considered. The Phase 1 grant application enabled the Tribe to begin the initial activities necessary to determine whether further consideration is warranted for hosting the MRS facility. The Tribe intends to pursue continued study of the MRS in order to meet the following objectives: (1) Continuing the education process towards a comprehensive understanding of the safety, environmental, technical, social and economic aspects of the MRS; (2) Conducting an effective public participation and information program; (3) Participating in MRS meetings.

  6. Stray light analysis of the Apache Point Observatory 3.5-meter telescope system

    NASA Astrophysics Data System (ADS)

    Pompea, Stephen M.; Pfisterer, Richard N.; Morgan, Jeffrey S.

    2003-02-01

    A stray light analysis of the Apache Point Observatory 3.5 meter telescope system was done to understand the performance for a variety of imaging modes. The telescope system consists of the 3.5-m telescope, its enclosure, and its associated imaging cameras. The purpose of the study was to assess the stray light performance of this system, identify where modification(s) would improve the system off-axis rejection characteristics, and assess the effectiveness of those modifications. A detailed telescope system geometry model was created, and scatter models were created for telescope and enclosure components. The computer model we created duplicated the pinhole stray light images taken with the telescope, thereby verifying the model. The Point Source Transmittance (PST), a commonly used metric for assessing stray light was used to evaluate the stray light performance of the system for a number of off-axis angles and to suggest modifications to enhance the system. The baseline PST of the existing system shows virtually no falloff with off-axis angle in the plane of the observatory slit. This is the result of (1) the focal plane having a large, unobstructed view of the Nasmyth mirror and cell, primary mirror cell, and baffles mounted on the Nasmyth cell, (2) relatively unobstructed illumination of telescope over a large range of angles in the plane of the slit, and (3) secondary and Nasmyth baffles that are not enclosed. These attributes create a series of first-level scatter paths that directly illuminate the focal plane. Our approach to stray light reduction was to address the light paths revealed by the various PST calculations. Our calculations have shown that significant gains can be realized with simple modifications to the telescope system.

  7. Geology and ground water in the central part of Apache County, Arizona

    USGS Publications Warehouse

    Akers, J.P.

    1965-01-01

    The central part of Apache County, Ariz., includes an area of about 3,300 square miles between the Navajo Indian Reservation to the north and U.S. Highway 60 to the south. Sedimentary rocks in the area range from Pennsylvanian to Quaternary in age and from 2,000 to more than 6,000 feet in thickness. The strata were tilted to the northeast, and part of the Upper Triassic and all the Jurassic and Lower Cretaceous rocks were eroded away before strata of Late Cretaceous age were deposited. Basaltic lava flows and cinder cones, representing four general periods of eruption in late Miocene to Quaternary time, are widespread in the southern part of the area. Pennsylvanian and Permian rocks overlie basement rocks of granite and diorite and include the Supai Formation, the Coconino Sandstone, and the Kaibab Limestone. The Supai Formation is 1,000 to 2,000 feet thick and consists of interbedded red and brown mudstone, siltstone, sandstone, limestone, and evaporites. It contains water of very poor quality outside Apache County. The Coconino Sandstone is 200 to 250 feet thick and consists of light-gray fine- to medium-grained sandstone. It contains water suitable for domestic use in the south and water unsuitable for most purposes in the north. The Coconino Sandstone underlies all Central Apache County in the subsurface. The yellowish-gray to dark-gray Kaibab Limestone is present in the southern two-thirds of the area and is 0 to 350 feet thick. It contains water where it is fractured and combines with the Coconino Sandstone to form a single hydrologic unit that yields from 6 to 74 gpm (gallons per minute) of water per foot of drawdown. An unconformity Heparates the Permian rocks from the overlying Triassic rocks, which comprise the Moenkopi and Chinle Formations and the Wingate Sandstone. The Moenkopi Formation is 35 to 250 feet thick and consists of intercalated brownish-red siltstone, sandstone, and conglomerate. It contains salty water in some areas but is dry in most. The

  8. Development and validation of a blade-element mathematical model for the AH-64A Apache helicopter

    NASA Technical Reports Server (NTRS)

    Mansur, M. Hossein

    1995-01-01

    A high-fidelity blade-element mathematical model for the AH-64A Apache Advanced Attack Helicopter has been developed by the Aeroflightdynamics Directorate of the U.S. Army's Aviation and Troop Command (ATCOM) at Ames Research Center. The model is based on the McDonnell Douglas Helicopter Systems' (MDHS) Fly Real Time (FLYRT) model of the AH-64A (acquired under contract) which was modified in-house and augmented with a blade-element-type main-rotor module. This report describes, in detail, the development of the rotor module, and presents some results of an extensive validation effort.

  9. Geologic and aeromagnetic map of a part of the Mescalero Apache Indian Reservation, Otero County, New Mexico

    SciTech Connect

    Moore, S.L.; Foord, E.E.; Meyer, G.A.

    1988-01-01

    This map covers approximately 600 square miles of the 750 square miles of the Mescalero Apache Indian Reservation in south-central New Mexico. Rocks exposed in the map area are chiefly gently dipping and gently folded Mesozoic and Paleozoic strata that are displaced by high-angle tensional faults into grabens, horsts, and tilted fault blocks. The Paleozoic strata were deposited unconformably on an eroded mountainous terrain of Precambrian syenite, melasyenite, quartz syenite, alkali granite, and alkali-granite pegmatite; the alkalic igneous rocks are dated at 1,150 /plus minus/ 40 m.y. by K/Ar methods.

  10. Randomized, controlled trial efficacy of pneumococcal conjugate vaccine against otitis media among Navajo and White Mountain Apache infants.

    PubMed

    O'Brien, Katherine L; David, Angeline B; Chandran, Aruna; Moulton, Lawrence H; Reid, Raymond; Weatherholtz, Robert; Santosham, Mathuram

    2008-01-01

    We report the phase III trial efficacy of 7-valent pneumococcal conjugate vaccine against clinical and culture proven otitis media (OM) among Navajo and White Mountain Apache infants. Efficacy was -0.4% (95% CI: -19.4 to 15.6) for clinically-diagnosed OM, 5.1% (95% CI: -51.5 to 40.6) for severe OM, and 64% (95% CI: -34% to 90%) for vaccine serotype pneumococcal OM suggesting that this vaccine is efficacious for pneumococcal OM in this high risk population. PMID:18162944

  11. Landscape associations of the sand fly, Lutzomyia (Heleocyrtomyia) apache (Diptera: Psychodidae), in the southwestern United States: a geographic information system analysis.

    PubMed

    Herrero, M V; Yarnell, W E; Schmidtmann, E T

    2004-12-01

    Landscape associations of the sand fly, Lutzomyia apache, Young and Perkins, in the southwestern U.S. were investigated by light/suction trap sampling and the development of a GIS-generated distribution map. In the mid-Rio Grande River valley, N.M., female and male L. apache were captured in updraft light/suction traps set in desert shrubland, irrigation levee, and bosque vegetation communities. Small numbers of flies were captured, but the presence of males and females in spatially separate and diverse plant communities at two locations suggest that L. apache are dispersed among available vegetation types. These data, along with 22 previously published collection site records, were used with a suite of physiographic features to characterize the biogeographic conditions suitable for L. apache. Suitable conditions encompass three life zones: the Rocky Mountain steppe province, the Colorado semi-plateau province, and the American semi-desert province, all within the dry domain region of the western U.S. The potential range of L. apache was then estimated based on elevation, mean and max - min temperature, precipitation, wet days, and relative humidity. The estimated range includes large contiguous areas in north-central Colorado, east-central New Mexico and west Texas, the lower mid-Rio Grande River valley, and southern Arizona, along with smaller, patchy, areas in northern Arizona, California, Nevada, Utah, and central Idaho. The spatial relationship between the estimated distribution of L. apache and the location of livestock exposed to vesicular stomatitis virus at the onset of recent outbreaks is presented. PMID:15707279

  12. Airborne radioactivity of portions of the Defiance Uplift and Carrizo Mountains, Apache county, Arizona

    USGS Publications Warehouse

    Johnson, R.W.; Moxham, R.M.

    1953-01-01

    The accompanying map shows the results of an airborne radioactivity survey covering 940 square miles in Apache county, Arizona. The survey was made by the U.S. Geological Survey from September 8 to October 3, 1952, as part of a cooperative program with the U.S. Atomic Energy Commission. The survey was made with scintillation-detection equipment mounted in a Douglas DC-3 aircraft. Parallel traverse lines, spaced at quarter-mile intervals, were flown approximately 500 feet above the ground. Aerial photographs were used for pilot guidance, and the flight path of the aircraft was recorded by a gyro-stabilized, continuous-strip-film camera. The distance of the aircraft from the ground was measured with a continuously recording radio altimeter. At 500 feet above the ground, the width of the zone from which anomalous radioactivity is measured varies with the intensity of radiation of the source and, for strong sources, the width would be as much as 1,400 feet. Quarter-mile spacing of the flight paths of the aircraft should be adequate to detect anomalies from strong sources of radioactivity. However, small areas of considerable radioactivity midway between flight paths may not be noted. The approximate location of each radioactivity anomaly is shown on the accompanying map. The plotted position of an anomaly may be in error by as much as a quarter of a mile owing to errors in the available base maps up to several square miles in which it is impossible to find and plot recognizable landmarks. The radioactivity anomaly that is recorded by airborne measurements at 500 feet above the ground can be caused by: 1. A moderately large area in which the rocks and soils are slightly more radioactive than the rocks and soils of the surrounding area. 2. A smaller area in which the rocks and soils are considerably more radioactive than rocks and soils in the surrounding area. 3. A very small area in which to rocks and soils are much more radioactive than the rocks and soils of the

  13. The Apache Longbow-Hellfire Missile Test at Yuma Proving Ground: Ecological Risk Assessment for Helicopter Overflight

    SciTech Connect

    Efroymson, Rebecca Ann; Hargrove, William Walter; Suter, Glenn

    2008-01-01

    A multi-stressor risk assessment was conducted at Yuma Proving Ground, Arizona, as a demonstration of the Military Ecological Risk Assessment Framework. The focus of the assessment was a testing program at Cibola Range, which involved an Apache Longbow helicopter firing Hellfire missiles at moving targets, M60-A1 tanks. This paper focuses on the wildlife risk assessment for the helicopter overflight. The primary stressors were sound and the view of the aircraft. Exposure to desert mule deer (Odocoileus hemionus crooki) was quantified using Air Force sound contour programs NOISEMAP and MR_NMAP, which gave very different results. Slant distance from helicopters to deer was also used as a measure of exposure that integrated risk from sound and view of the aircraft. Exposure-response models for the characterization of effects consisted of behavioral thresholds in sound exposure level or maximum sound level units or slant distance. Available sound thresholds were limited for desert mule deer, but a distribution of slant-distance thresholds was available for ungulates. The risk characterization used a weight-of-evidence approach and concluded that risk to mule deer behavior from the Apache overflight is uncertain, but that no risk to mule deer abundance and reproduction is expected.

  14. Charters, Constitutions and By-Laws of the Indian Tribes of North America; Part III: The Southwest (Apache--Mohave). Occasional Publications in Anthropology Ethnology Series No. 4.

    ERIC Educational Resources Information Center

    Fay, George E., Comp.

    The Museum of Anthropology of the University of Northern Colorado (formerly known as Colorado State College) has assembled a large number of Indian tribal charters, constitutions, and by-laws to be reproduced as a series of publications. Included in this volume are the amended charter and constitution of the Jicarilla Apache Tribe, Dulce, New…

  15. Formal Education on the White Mountain Apache Reservation; Report of a Self-Study Conference. The National Study of American Indian Education, Series I, No. 25, Final Report.

    ERIC Educational Resources Information Center

    Anderson, Ned; Chilcott, John H.

    In one phase of the National Study of American Indian Education, local Indian communities were encouraged to conduct their own self-studies of American Indian education. In keeping with this, a conference was held to determine the attitudinal responses of White Mountain Apaches (aged 20-48) to the following general topics concerning Indian…

  16. Statement of Hubert Velarde, Jicarilla Apache Tribe to United States Commission on Civil Rights at Albuquerque Convention Center (Albuquerque, New Mexico, November 14, 1972).

    ERIC Educational Resources Information Center

    Velarde, Hubert

    The statement by the President of the Jicarilla Apache Tribe emphasizes reservation problems that need to be examined. Presented at a 1972 Civil Rights Commission hearing on Indian Concerns, Velarde's statement listed employment, education, the administration of justice, water rights, and medical services as areas for investigation. (KM)

  17. Infrared Spectroscopic Data from the Apache Point Observatory Galactic Evolution Experiment (APOGEE), SDSS-III Data Release 10

    DOE Data Explorer

    Sloan Digital Sky Survey (SDSS) Data Release 10 is the first spectroscopic release from the Apache Point Observatory Galactic Evolution Experiment (APOGEE), including spectra and derived stellar parameters for more than 50,000 stars. APOGEE is an ongoing survey of ~100,000 stars accessing all parts of the Milky Way. By operating in the infrared (H-band) portion of the electromagnetic spectrum, APOGEE is better able to detect light from stars lying in dusty regions of the Milky Way than surveys conducted in the optical, making this survey particularly well-suited for exploring the Galactic disk and bulge. APOGEE's high resolution spectra provide detailed information about the stellar atmospheres; DR10 provides derived effective temperatures, surface gravities, overall metallicities, and information on the abundances of several chemical elements. [copied from http://www.sdss3.org/dr10/irspec/

  18. Inequalities in Open Source Software Development: Analysis of Contributor’s Commits in Apache Software Foundation Projects

    PubMed Central

    2016-01-01

    While researchers are becoming increasingly interested in studying OSS phenomenon, there is still a small number of studies analyzing larger samples of projects investigating the structure of activities among OSS developers. The significant amount of information that has been gathered in the publicly available open-source software repositories and mailing-list archives offers an opportunity to analyze projects structures and participant involvement. In this article, using on commits data from 263 Apache projects repositories (nearly all), we show that although OSS development is often described as collaborative, but it in fact predominantly relies on radically solitary input and individual, non-collaborative contributions. We also show, in the first published study of this magnitude, that the engagement of contributors is based on a power-law distribution. PMID:27096157

  19. High-Precision Lunar Ranging and Gravitational Parameter Estimation With the Apache Point Observatory Lunar Laser-ranging Operation

    NASA Astrophysics Data System (ADS)

    Johnson, Nathan H.

    This dissertation is concerned with several problems of instrumentation and data analysis encountered by the Apache Point Observatory Lunar Laser-ranging Operation. Chapter 2 considers crosstalk between elements of a single-photon avalanche photodiode detector. Experimental and analytic methods were developed to determine crosstalk rates, and empirical findings are presented. Chapter 3 details electronics developments that have improved the quality of data collected by detectors of the same type. Chapter 4 explores the challenges of estimating gravitational parameters on the basis of ranging data collected by this and other experiments and presents resampling techniques for the derivation of standard errors for estimates of such parameters determined by the Planetary Ephemeris Program (PEP), a solar-system model and data-fitting code. Possible directions for future work are discussed in Chapter 5. A manual of instructions for working with PEP is presented as an appendix.

  20. The Apache Point Observatory Galactic Evolution Experiment (APOGEE) in Sloan Digital Sky Survey III (SDSS-III)

    NASA Astrophysics Data System (ADS)

    Majewski, Steven R.; Wilson, John C.; Hearty, Fred; Schiavon, Ricardo R.; Skrutskie, Michael F.

    2010-03-01

    The Apache Point Observatory Galactic Evolution Experiment (APOGEE) is a large-scale, near-infrared (H-band), high-resolution (R ~ 30,000), high S/N (≳100) spectroscopic survey of Milky Way stellar populations. APOGEE will operate from 1.51-1.68μm, a region that includes useful absorption lines from at least fifteen chemical species including α, odd-Z, and iron peak elements. The APOGEE instrument has a novel design featuring 300 science fibers feeding light to a mosaiced VPH grating and a six-element camera encased in a liquid nitrogen-cooled cryostat. A three year bright-time observing campaign will enable APOGEE to observe approximately 100,000 red giants across the Galactic bulge, disk and halo.

  1. Sloan Digital Sky Survey II (SDSS-II) Supernova Data

    DOE Data Explorer

    The Sloan Digital Sky Survey (SDSS) is a series of three interlocking imaging and spectroscopic surveys, carried out over an eight-year period with a dedicated 2.5m telescope located at Apache Point Observatory in Southern New Mexico. The SDSS Supernova Survey was one of those three components of SDSS and SDSS-II, a 3-year extension of the original SDSS that operated from July 2005 to July 2008. The Supernova Survey was a time-domain survey, involving repeat imaging of the same region of sky every other night, weather permitting. The primary scientific motivation was to detect and measure light curves for several hundred supernovae through repeat scans of the SDSS Southern equatorial stripe 82 (about 2.5? wide by ~120? long). Over the course of three 3-month campaigns SDSS-II SN discovered and measured multi-band lightcurves for ~500 spectroscopically confirmed Type Ia supernovae in the redshift range z=0.05-0.4. In addition, the project harvested a few hundred light curves for SNe Ia and discovered about 80 spectroscopically confirmed core-collapse supernovae (supernova types Ib/c and II).

  2. Demonstration of the Military Ecological Risk Assessment Framework (MERAF): Apache Longbow - Hell Missile Test at Yuma Proving Ground

    SciTech Connect

    Efroymson, R.A.

    2002-05-09

    This ecological risk assessment for a testing program at Yuma Proving Ground, Arizona, is a demonstration of the Military Ecological Risk Assessment Framework (MERAF; Suter et al. 2001). The demonstration is intended to illustrate how risk assessment guidance concerning-generic military training and testing activities and guidance concerning a specific type of activity (e.g., low-altitude aircraft overflights) may be implemented at a military installation. MERAF was developed with funding from the Strategic Research and Development Program (SERDP) of the Department of Defense. Novel aspects of MERAF include: (1) the assessment of risks from physical stressors using an ecological risk assessment framework, (2) the consideration of contingent or indirect effects of stressors (e.g., population-level effects that are derived from habitat or hydrological changes), (3) the integration of risks associated with different component activities or stressors, (4) the emphasis on quantitative risk estimates and estimates of uncertainty, and (5) the modularity of design, permitting components of the framework to be used in various military risk assessments that include similar activities. The particular subject of this report is the assessment of ecological risks associated with a testing program at Cibola Range of Yuma Proving Ground, Arizona. The program involves an Apache Longbow helicopter firing Hellfire missiles at moving targets, i.e., M60-A1 tanks. Thus, the three component activities of the Apache-Hellfire test were: (1) helicopter overflight, (2) missile firing, and (3) tracked vehicle movement. The demonstration was limited, to two ecological endpoint entities (i.e., potentially susceptible and valued populations or communities): woody desert wash communities and mule deer populations. The core assessment area is composed of about 126 km{sup 2} between the Chocolate and Middle Mountains. The core time of the program is a three-week period, including fourteen days of

  3. The effect of a monocular helmet-mounted display on aircrew health: a 10-year prospective cohort study of Apache AH MK 1 pilots: study midpoint update

    NASA Astrophysics Data System (ADS)

    Hiatt, Keith L.; Rash, Clarence E.; Watters, Raymond W.; Adams, Mark S.

    2009-05-01

    A collaborative occupational health study has been undertaken by Headquarters Army Aviation, Middle Wallop, UK, and the U.S. Army Aeromedical Research Laboratory, Fort Rucker, Alabama, to determine if the use of the Integrated Helmet and Display Sighting System (IHADSS) monocular helmet-mounted display (HMD) in the Apache AH Mk 1 attack helicopter has any long-term (10-year) effect on visual performance. The test methodology consists primarily of a detailed questionnaire and an annual battery of vision tests selected to capture changes in visual performance of Apache aviators over their flight career (with an emphasis on binocular visual function). Pilots using binocular night vision goggles serve as controls and undergo the same methodology. Currently, at the midpoint of the study, with the exception of a possible colour discrimination effect, there are no data indicating that the long-term use of the IHADSS monocular HMD results in negative effects on vision.

  4. Preliminary Geochemical and Petrologic Assessment of the Fanney Rhyolite and the Bloodgood Canyon and Apache Springs tuffs, Mogollon-Datil Volcanic Field, New Mexico

    NASA Astrophysics Data System (ADS)

    Salings, E. E.; Rentz, S. P.; Michelfelder, G.; Sikes, E. R.

    2015-12-01

    Continental arc volcanoes represent a dramatic expression of a significant and fundamental phenomena in global tectonics: the subduction of an oceanic plate beneath a more buoyant continental plate. The subduction of an oceanic plate results in recycling of crustal material into the convecting mantle, partial melting, and primary basalt production. Moreover, during passage through thick continental crust, subduction zone magmas may substantially differentiate and melt crustal rocks giving rise to the great diversity of igneous lithologies characteristic of earth. These are important processes that must be understood in detail in order to interpret the long-term evolution of the earth and continental crust. Here we present variations in the isotopic and trace element composition of volcanic rocks from Bloodgood Canyon and Apache Springs tuffs, and the Fanney Rhyolite located in the western Mogollon-Datil Volcanic Field (MDVF). The project will address several questions. First, are the Bloodgood and Apache Springs tuffs and Fanney Rhyolite petrogenically related, and are these rhyolites expressions of a continental arc ignimbrite flare-up? Second, what petrogenic processes affected differentiation and where is the magma sourced? Finally, to what extent do these units represent a manifestation of the MDVF and the transition from arc magmatism to rifting? The Bloodgood Canyon is a crystal-rich rhyolite tuff containing quartz>k-feldspar>plagioclase>biotite, and pumice and lithic fragments. Rb ranges from 230-330ppm, Sr from 14-83ppm, and 87Sr/86Srm from 0.71619-0.72477.The Apache Springs Tuff is a rhyolite tuff containing quartz>k-feldspar>plagioclase>biotite, and lithics. Rb (228-233ppm) and 87Sr/86Srm (0.71025-0.71056) are restricted, while Sr (105-399ppm) is more variable in composition. The Fanney Creek is a massive rhyolite lava with flow banding and contains quartz phenocryst clusters and k-feldspars. Currently, no data exists for the Apache Springs Tuff.

  5. Association of serum interleukin-6, interleukin-8, and Acute Physiology and Chronic Health Evaluation II score with clinical outcome in patients with acute respiratory distress syndrome

    PubMed Central

    Swaroopa, Deme; Bhaskar, Kakarla; Mahathi, T.; Katkam, Shivakrishna; Raju, Y. Satyanarayana; Chandra, Naval; Kutala, Vijay Kumar

    2016-01-01

    Background and Aim: Studies on potential biomarkers in experimental models of acute lung injury (ALI) and clinical samples from patients with ALI have provided evidence to the pathophysiology of the mechanisms of lung injury and predictor of clinical outcome. Because of the high mortality and substantial variability in outcomes in patients with acute respiratory distress syndrome (ARDS), identification of biomarkers such as cytokines is important to determine prognosis and guide clinical decision-making. Materials and Methods: In this study, we have included thirty patients admitted to Intensive Care Unit diagnosed with ARDS, and serum samples were collected on day 1 and 7 and were analyzed for serum interleukin-6 (IL-6) and IL-8 by ELISA method, and Acute Physiology and Chronic Health Evaluation II (APACHE II) scoring was done on day 1. Results: The mortality in the patients observed with ARDS was 34%. APACHE II score was significantly higher in nonsurvivors as compared to survivors. There were no significant differences in gender and biochemical and hematological parameters among the survivors and nonsurvivors. Serum IL-6 and IL-8 levels on day 1 were significantly higher in all the ARDS patients as compared to healthy controls and these levels were returned to near-normal basal levels on day 7. The serum IL-6 and IL-8 levels measured on day 7 were of survivors. As compared to survivors, the IL-6 and IL-8 levels were significantly higher in nonsurvivors measured on day 1. Spearman's rank correlation analysis indicated a significant positive correlation of APACHE II with IL-8. By using APACHE II score, IL-6, and IL-8, the receiver operating characteristic curve was plotted and the provided predictable accuracy of mortality (outcome) was 94%. Conclusion: The present study highlighted the importance of measuring the cytokines such as IL-6 and IL-8 in patients with ARDS in predicting the clinical outcome. PMID:27688627

  6. Association of serum interleukin-6, interleukin-8, and Acute Physiology and Chronic Health Evaluation II score with clinical outcome in patients with acute respiratory distress syndrome

    PubMed Central

    Swaroopa, Deme; Bhaskar, Kakarla; Mahathi, T.; Katkam, Shivakrishna; Raju, Y. Satyanarayana; Chandra, Naval; Kutala, Vijay Kumar

    2016-01-01

    Background and Aim: Studies on potential biomarkers in experimental models of acute lung injury (ALI) and clinical samples from patients with ALI have provided evidence to the pathophysiology of the mechanisms of lung injury and predictor of clinical outcome. Because of the high mortality and substantial variability in outcomes in patients with acute respiratory distress syndrome (ARDS), identification of biomarkers such as cytokines is important to determine prognosis and guide clinical decision-making. Materials and Methods: In this study, we have included thirty patients admitted to Intensive Care Unit diagnosed with ARDS, and serum samples were collected on day 1 and 7 and were analyzed for serum interleukin-6 (IL-6) and IL-8 by ELISA method, and Acute Physiology and Chronic Health Evaluation II (APACHE II) scoring was done on day 1. Results: The mortality in the patients observed with ARDS was 34%. APACHE II score was significantly higher in nonsurvivors as compared to survivors. There were no significant differences in gender and biochemical and hematological parameters among the survivors and nonsurvivors. Serum IL-6 and IL-8 levels on day 1 were significantly higher in all the ARDS patients as compared to healthy controls and these levels were returned to near-normal basal levels on day 7. The serum IL-6 and IL-8 levels measured on day 7 were of survivors. As compared to survivors, the IL-6 and IL-8 levels were significantly higher in nonsurvivors measured on day 1. Spearman's rank correlation analysis indicated a significant positive correlation of APACHE II with IL-8. By using APACHE II score, IL-6, and IL-8, the receiver operating characteristic curve was plotted and the provided predictable accuracy of mortality (outcome) was 94%. Conclusion: The present study highlighted the importance of measuring the cytokines such as IL-6 and IL-8 in patients with ARDS in predicting the clinical outcome.

  7. The Apache Point Observatory Galactic Evolution Experiment (APOGEE) high-resolution near-infrared multi-object fiber spectrograph

    NASA Astrophysics Data System (ADS)

    Wilson, John C.; Hearty, Fred; Skrutskie, Michael F.; Majewski, Steven; Schiavon, Ricardo; Eisenstein, Daniel; Gunn, Jim; Blank, Basil; Henderson, Chuck; Smee, Stephen; Barkhouser, Robert; Harding, Al; Fitzgerald, Greg; Stolberg, Todd; Arns, Jim; Nelson, Matt; Brunner, Sophia; Burton, Adam; Walker, Eric; Lam, Charles; Maseman, Paul; Barr, Jim; Leger, French; Carey, Larry; MacDonald, Nick; Horne, Todd; Young, Erick; Rieke, George; Rieke, Marcia; O'Brien, Tom; Hope, Steve; Krakula, John; Crane, Jeff; Zhao, Bo; Carr, Mike; Harrison, Craig; Stoll, Robert; Vernieri, Mary A.; Holtzman, Jon; Shetrone, Matt; Allende-Prieto, Carlos; Johnson, Jennifer; Frinchaboy, Peter; Zasowski, Gail; Bizyaev, Dmitry; Gillespie, Bruce; Weinberg, David

    2010-07-01

    The Apache Point Observatory Galactic Evolution Experiment (APOGEE) will use a dedicated 300-fiber, narrow-band (1.5-1.7 micron), high resolution (R~30,000), near-infrared spectrograph to survey approximately 100,000 giant stars across the Milky Way. This survey, conducted as part of the Sloan Digital Sky Survey III (SDSS III), will revolutionize our understanding of kinematical and chemical enrichment histories of all Galactic stellar populations. The instrument, currently in fabrication, will be housed in a separate building adjacent to the 2.5 m SDSS telescope and fed light via approximately 45-meter fiber runs from the telescope. The instrument design includes numerous technological challenges and innovations including a gang connector that allows simultaneous connection of all fibers with a single plug to a telescope cartridge that positions the fibers on the sky, numerous places in the fiber train in which focal ratio degradation must be minimized, a large (290 mm x 475 mm elliptically-shaped recorded area) mosaic-VPH, an f/1.4 sixelement refractive camera featuring silicon and fused silica elements with diameters as large as 393 mm, three near-within a custom, LN2-cooled, stainless steel vacuum cryostat with dimensions 1.4 m x 2.3 m x 1.3 m.

  8. Developing Online Communities with LAMP (Linux, Apache, MySQL, PHP) - the IMIA OSNI and CHIRAD Experiences.

    PubMed

    Murray, Peter J; Oyri, Karl

    2005-01-01

    Many health informatics organisations do not seem to use, on a practical basis, for the benefit of their activities and interaction with their members, the very technologies that they often promote for use within healthcare environments. In particular, many organisations seem to be slow to take up the benefits of interactive web technologies. This paper presents an introduction to some of the many free/libre and open source (FLOSS) applications currently available and using the LAMP - Linux, Apache, MySQL, PHP architecture - as a way of cheaply deploying reliable, scalable, and secure web applications. The experience of moving to applications using LAMP architecture, in particular that of the Open Source Nursing Informatics (OSNI) Working Group of the Special Interest Group in Nursing Informatics of the International Medical Informatics Association (IMIA-NI), in using PostNuke, a FLOSS Content Management System (CMS) illustrates many of the benefits of such applications. The experiences of the authors in installing and maintaining a large number of websites using FLOSS CMS to develop dynamic, interactive websites that facilitate real engagement with the members of IMIA-NI OSNI, the IMIA Open Source Working Group, and the Centre for Health Informatics Research and Development (CHIRAD), as well as other organisations, is used as the basis for discussing the potential benefits that could be realised by others within the health informatics community. PMID:16160284

  9. THE APACHE POINT OBSERVATORY GALACTIC EVOLUTION EXPERIMENT: FIRST DETECTION OF HIGH-VELOCITY MILKY WAY BAR STARS

    SciTech Connect

    Nidever, David L.; Zasowski, Gail; Majewski, Steven R.; Beaton, Rachael L.; Wilson, John C.; Skrutskie, Michael F.; O'Connell, Robert W.; Bird, Jonathan; Schoenrich, Ralph; Johnson, Jennifer A.; Sellgren, Kris; Robin, Annie C.; Schultheis, Mathias; Martinez-Valpuesta, Inma; Gerhard, Ortwin; Shetrone, Matthew; Schiavon, Ricardo P.; Weiner, Benjamin; Schneider, Donald P.; Allende Prieto, Carlos; and others

    2012-08-20

    Commissioning observations with the Apache Point Observatory Galactic Evolution Experiment (APOGEE), part of the Sloan Digital Sky Survey III, have produced radial velocities (RVs) for {approx}4700 K/M-giant stars in the Milky Way (MW) bulge. These high-resolution (R {approx} 22, 500), high-S/N (>100 per resolution element), near-infrared (NIR; 1.51-1.70 {mu}m) spectra provide accurate RVs ({epsilon}{sub V} {approx} 0.2 km s{sup -1}) for the sample of stars in 18 Galactic bulge fields spanning -1 Degree-Sign -32 Degree-Sign . This represents the largest NIR high-resolution spectroscopic sample of giant stars ever assembled in this region of the Galaxy. A cold ({sigma}{sub V} {approx} 30 km s{sup -1}), high-velocity peak (V{sub GSR} Almost-Equal-To +200 km s{sup -1}) is found to comprise a significant fraction ({approx}10%) of stars in many of these fields. These high RVs have not been detected in previous MW surveys and are not expected for a simple, circularly rotating disk. Preliminary distance estimates rule out an origin from the background Sagittarius tidal stream or a new stream in the MW disk. Comparison to various Galactic models suggests that these high RVs are best explained by stars in orbits of the Galactic bar potential, although some observational features remain unexplained.

  10. The Apache Longbow-Hellfire Missile Test at Yuma Proving Ground: Ecological Risk Assessment for Missile Firing

    SciTech Connect

    Jones, Daniel Steven; Efroymson, Rebecca Ann; Hargrove, William Walter; Suter, Glenn; Pater, Larry

    2008-01-01

    A multiple stressor risk assessment was conducted at Yuma Proving Ground, Arizona, as a demonstration of the Military Ecological Risk Assessment Framework. The focus was a testing program at Cibola Range, which involved an Apache Longbow helicopter firing Hellfire missiles at moving targets, M60- A1 tanks. This paper describes the ecological risk assessment for the missile launch and detonation. The primary stressor associated with this activity was sound. Other minor stressors included the detonation impact, shrapnel, and fire. Exposure to desert mule deer (Odocoileus hemionus crooki) was quantified using the Army sound contour program BNOISE2, as well as distances from the explosion to deer. Few effects data were available from related studies. Exposure-response models for the characterization of effects consisted of human "disturbance" and hearing damage thresholds in units of C-weighted decibels (sound exposure level) and a distance-based No Observed Adverse Effects Level for moose and cannonfire. The risk characterization used a weight-of-evidence approach and concluded that risk to mule deer behavior from the missile firing was likely for a negligible number of deer, but that no risk to mule deer abundance and reproduction is expected.

  11. Data collection and field experiments at the Apache Leap research site. Annual report, May 1995--1996

    SciTech Connect

    Woodhouse, E.G.; Bassett, R.L.; Neuman, S.P.; Chen, G.

    1997-08-01

    This report documents the research performed during the period May 1995-May 1996 for a project of the U.S. Regulatory Commission (sponsored contract NRC-04-090-051) by the University of Arizona. The project manager for this research in Thomas J. Nicholson, Office of Nuclear Regulatory Research. The objectives of this research were to examine hypotheses and test alternative conceptual models concerning unsaturated flow and transport through fractured rock, and to design and execute confirmatory field and laboratory experiments to test these hypotheses and conceptual models at the Apache Leap Research Site near Superior, Arizona. Each chapter in this report summarizes research related to a specific set of objectives and can be read and interpreted as a separate entity. Topics include: crosshole pneumatic and gaseous tracer field and modeling experiments designed to help validate the applicability of contiuum geostatistical and stochastic concepts, theories, models, and scaling relations relevant to unsaturated flow and transport in fractured porous tuffs; use of geochemistry and aquifer testing to evaluate fracture flow and perching mechanisms; investigations of {sup 234}U/{sup 238}U fractionation to evaluate leaching selectivity; and transport and modeling of both conservative and non-conservative tracers.

  12. Developing Online Communities with LAMP (Linux, Apache, MySQL, PHP) - the IMIA OSNI and CHIRAD Experiences.

    PubMed

    Murray, Peter J; Oyri, Karl

    2005-01-01

    Many health informatics organisations do not seem to use, on a practical basis, for the benefit of their activities and interaction with their members, the very technologies that they often promote for use within healthcare environments. In particular, many organisations seem to be slow to take up the benefits of interactive web technologies. This paper presents an introduction to some of the many free/libre and open source (FLOSS) applications currently available and using the LAMP - Linux, Apache, MySQL, PHP architecture - as a way of cheaply deploying reliable, scalable, and secure web applications. The experience of moving to applications using LAMP architecture, in particular that of the Open Source Nursing Informatics (OSNI) Working Group of the Special Interest Group in Nursing Informatics of the International Medical Informatics Association (IMIA-NI), in using PostNuke, a FLOSS Content Management System (CMS) illustrates many of the benefits of such applications. The experiences of the authors in installing and maintaining a large number of websites using FLOSS CMS to develop dynamic, interactive websites that facilitate real engagement with the members of IMIA-NI OSNI, the IMIA Open Source Working Group, and the Centre for Health Informatics Research and Development (CHIRAD), as well as other organisations, is used as the basis for discussing the potential benefits that could be realised by others within the health informatics community.

  13. Chronic Liver Failure-Sequential Organ Failure Assessment is better than the Asia-Pacific Association for the Study of Liver criteria for defining acute-on-chronic liver failure and predicting outcome

    PubMed Central

    Dhiman, Radha K; Agrawal, Swastik; Gupta, Tarana; Duseja, Ajay; Chawla, Yogesh

    2014-01-01

    AIM: To compare the utility of the Chronic Liver Failure-Sequential Organ Failure Assessment (CLIF-SOFA) and Asia-Pacific Association for the Study of Liver (APASL) definitions of acute-on-chronic liver failure (ACLF) in predicting short-term prognosis of patients with ACLF. METHODS: Consecutive patients of cirrhosis with acute decompensation were prospectively included. They were grouped into ACLF and no ACLF groups as per CLIF-SOFA and APASL criteria. Patients were followed up for 3 mo from inclusion or mortality whichever was earlier. Mortality at 28-d and 90-d was compared between no ACLF and ACLF groups as per both criteria. Mortality was also compared between different grades of ACLF as per CLIF-SOFA criteria. Prognostic scores like CLIF-SOFA, Acute Physiology and Chronic Health Evaluation (APACHE)-II, Child-Pugh and Model for End-Stage Liver Disease (MELD) scores were evaluated for their ability to predict 28-d mortality using area under receiver operating curves (AUROC). RESULTS: Of 50 patients, 38 had ACLF as per CLIF-SOFA and 19 as per APASL criteria. Males (86%) were predominant, alcoholic liver disease (68%) was the most common etiology of cirrhosis, sepsis (66%) was the most common cause of acute decompensation while infection (66%) was the most common precipitant of acute decompensation. The 28-d mortality in no ACLF and ACLF groups was 8.3% and 47.4% (P = 0.018) as per CLIF-SOFA and 39% and 37% (P = 0.895) as per APASL criteria. The 28-d mortality in patients with no ACLF (n = 12), ACLF grade 1 (n = 11), ACLF grade 2 (n = 14) and ACLF grade 3 (n = 13) as per CLIF-SOFA criteria was 8.3%, 18.2%, 42.9% and 76.9% (χ2 for trend, P = 0.002) and 90-d mortality was 16.7%, 27.3%, 78.6% and 100% (χ2 for trend, P < 0.0001) respectively. Patients with prior decompensation had similar 28-d and 90-d mortality (39.3% and 53.6%) as patients without prior decompensation (36.4% and 63.6%) (P = NS). AUROCs for 28-d mortality were 0.795, 0.787, 0.739 and 0.710 for

  14. OVERVIEW OF THE SDSS-IV MaNGA SURVEY: MAPPING NEARBY GALAXIES AT APACHE POINT OBSERVATORY

    SciTech Connect

    Bundy, Kevin; Bershady, Matthew A.; Wake, David A.; Tremonti, Christy; Diamond-Stanic, Aleksandar M.; Law, David R.; Cherinka, Brian; Yan, Renbin; Sánchez-Gallego, José R.; Drory, Niv; MacDonald, Nicholas; Weijmans, Anne-Marie; Thomas, Daniel; Masters, Karen; Coccato, Lodovico; Aragón-Salamanca, Alfonso; Avila-Reese, Vladimir; Badenes, Carles; Falcón-Barroso, Jésus; Belfiore, Francesco; and others

    2015-01-01

    We present an overview of a new integral field spectroscopic survey called MaNGA (Mapping Nearby Galaxies at Apache Point Observatory), one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV) that began on 2014 July 1. MaNGA will investigate the internal kinematic structure and composition of gas and stars in an unprecedented sample of 10,000 nearby galaxies. We summarize essential characteristics of the instrument and survey design in the context of MaNGA's key science goals and present prototype observations to demonstrate MaNGA's scientific potential. MaNGA employs dithered observations with 17 fiber-bundle integral field units that vary in diameter from 12'' (19 fibers) to 32'' (127 fibers). Two dual-channel spectrographs provide simultaneous wavelength coverage over 3600-10300 Å at R ∼ 2000. With a typical integration time of 3 hr, MaNGA reaches a target r-band signal-to-noise ratio of 4-8 (Å{sup –1} per 2'' fiber) at 23 AB mag arcsec{sup –2}, which is typical for the outskirts of MaNGA galaxies. Targets are selected with M {sub *} ≳ 10{sup 9} M {sub ☉} using SDSS-I redshifts and i-band luminosity to achieve uniform radial coverage in terms of the effective radius, an approximately flat distribution in stellar mass, and a sample spanning a wide range of environments. Analysis of our prototype observations demonstrates MaNGA's ability to probe gas ionization, shed light on recent star formation and quenching, enable dynamical modeling, decompose constituent components, and map the composition of stellar populations. MaNGA's spatially resolved spectra will enable an unprecedented study of the astrophysics of nearby galaxies in the coming 6 yr.

  15. Overview of the SDSS-IV MaNGA Survey: Mapping nearby Galaxies at Apache Point Observatory

    NASA Astrophysics Data System (ADS)

    Bundy, Kevin; Bershady, Matthew A.; Law, David R.; Yan, Renbin; Drory, Niv; MacDonald, Nicholas; Wake, David A.; Cherinka, Brian; Sánchez-Gallego, José R.; Weijmans, Anne-Marie; Thomas, Daniel; Tremonti, Christy; Masters, Karen; Coccato, Lodovico; Diamond-Stanic, Aleksandar M.; Aragón-Salamanca, Alfonso; Avila-Reese, Vladimir; Badenes, Carles; Falcón-Barroso, Jésus; Belfiore, Francesco; Bizyaev, Dmitry; Blanc, Guillermo A.; Bland-Hawthorn, Joss; Blanton, Michael R.; Brownstein, Joel R.; Byler, Nell; Cappellari, Michele; Conroy, Charlie; Dutton, Aaron A.; Emsellem, Eric; Etherington, James; Frinchaboy, Peter M.; Fu, Hai; Gunn, James E.; Harding, Paul; Johnston, Evelyn J.; Kauffmann, Guinevere; Kinemuchi, Karen; Klaene, Mark A.; Knapen, Johan H.; Leauthaud, Alexie; Li, Cheng; Lin, Lihwai; Maiolino, Roberto; Malanushenko, Viktor; Malanushenko, Elena; Mao, Shude; Maraston, Claudia; McDermid, Richard M.; Merrifield, Michael R.; Nichol, Robert C.; Oravetz, Daniel; Pan, Kaike; Parejko, John K.; Sanchez, Sebastian F.; Schlegel, David; Simmons, Audrey; Steele, Oliver; Steinmetz, Matthias; Thanjavur, Karun; Thompson, Benjamin A.; Tinker, Jeremy L.; van den Bosch, Remco C. E.; Westfall, Kyle B.; Wilkinson, David; Wright, Shelley; Xiao, Ting; Zhang, Kai

    2015-01-01

    We present an overview of a new integral field spectroscopic survey called MaNGA (Mapping Nearby Galaxies at Apache Point Observatory), one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV) that began on 2014 July 1. MaNGA will investigate the internal kinematic structure and composition of gas and stars in an unprecedented sample of 10,000 nearby galaxies. We summarize essential characteristics of the instrument and survey design in the context of MaNGA's key science goals and present prototype observations to demonstrate MaNGA's scientific potential. MaNGA employs dithered observations with 17 fiber-bundle integral field units that vary in diameter from 12'' (19 fibers) to 32'' (127 fibers). Two dual-channel spectrographs provide simultaneous wavelength coverage over 3600-10300 Å at R ~ 2000. With a typical integration time of 3 hr, MaNGA reaches a target r-band signal-to-noise ratio of 4-8 (Å-1 per 2'' fiber) at 23 AB mag arcsec-2, which is typical for the outskirts of MaNGA galaxies. Targets are selected with M * >~ 109 M ⊙ using SDSS-I redshifts and i-band luminosity to achieve uniform radial coverage in terms of the effective radius, an approximately flat distribution in stellar mass, and a sample spanning a wide range of environments. Analysis of our prototype observations demonstrates MaNGA's ability to probe gas ionization, shed light on recent star formation and quenching, enable dynamical modeling, decompose constituent components, and map the composition of stellar populations. MaNGA's spatially resolved spectra will enable an unprecedented study of the astrophysics of nearby galaxies in the coming 6 yr.

  16. NeuroPigPen: A Scalable Toolkit for Processing Electrophysiological Signal Data in Neuroscience Applications Using Apache Pig.

    PubMed

    Sahoo, Satya S; Wei, Annan; Valdez, Joshua; Wang, Li; Zonjy, Bilal; Tatsuoka, Curtis; Loparo, Kenneth A; Lhatoo, Samden D

    2016-01-01

    The recent advances in neurological imaging and sensing technologies have led to rapid increase in the volume, rate of data generation, and variety of neuroscience data. This "neuroscience Big data" represents a significant opportunity for the biomedical research community to design experiments using data with greater timescale, large number of attributes, and statistically significant data size. The results from these new data-driven research techniques can advance our understanding of complex neurological disorders, help model long-term effects of brain injuries, and provide new insights into dynamics of brain networks. However, many existing neuroinformatics data processing and analysis tools were not built to manage large volume of data, which makes it difficult for researchers to effectively leverage this available data to advance their research. We introduce a new toolkit called NeuroPigPen that was developed using Apache Hadoop and Pig data flow language to address the challenges posed by large-scale electrophysiological signal data. NeuroPigPen is a modular toolkit that can process large volumes of electrophysiological signal data, such as Electroencephalogram (EEG), Electrocardiogram (ECG), and blood oxygen levels (SpO2), using a new distributed storage model called Cloudwave Signal Format (CSF) that supports easy partitioning and storage of signal data on commodity hardware. NeuroPigPen was developed with three design principles: (a) Scalability-the ability to efficiently process increasing volumes of data; (b) Adaptability-the toolkit can be deployed across different computing configurations; and (c) Ease of programming-the toolkit can be easily used to compose multi-step data processing pipelines using high-level programming constructs. The NeuroPigPen toolkit was evaluated using 750 GB of electrophysiological signal data over a variety of Hadoop cluster configurations ranging from 3 to 30 Data nodes. The evaluation results demonstrate that the toolkit

  17. NeuroPigPen: A Scalable Toolkit for Processing Electrophysiological Signal Data in Neuroscience Applications Using Apache Pig.

    PubMed

    Sahoo, Satya S; Wei, Annan; Valdez, Joshua; Wang, Li; Zonjy, Bilal; Tatsuoka, Curtis; Loparo, Kenneth A; Lhatoo, Samden D

    2016-01-01

    The recent advances in neurological imaging and sensing technologies have led to rapid increase in the volume, rate of data generation, and variety of neuroscience data. This "neuroscience Big data" represents a significant opportunity for the biomedical research community to design experiments using data with greater timescale, large number of attributes, and statistically significant data size. The results from these new data-driven research techniques can advance our understanding of complex neurological disorders, help model long-term effects of brain injuries, and provide new insights into dynamics of brain networks. However, many existing neuroinformatics data processing and analysis tools were not built to manage large volume of data, which makes it difficult for researchers to effectively leverage this available data to advance their research. We introduce a new toolkit called NeuroPigPen that was developed using Apache Hadoop and Pig data flow language to address the challenges posed by large-scale electrophysiological signal data. NeuroPigPen is a modular toolkit that can process large volumes of electrophysiological signal data, such as Electroencephalogram (EEG), Electrocardiogram (ECG), and blood oxygen levels (SpO2), using a new distributed storage model called Cloudwave Signal Format (CSF) that supports easy partitioning and storage of signal data on commodity hardware. NeuroPigPen was developed with three design principles: (a) Scalability-the ability to efficiently process increasing volumes of data; (b) Adaptability-the toolkit can be deployed across different computing configurations; and (c) Ease of programming-the toolkit can be easily used to compose multi-step data processing pipelines using high-level programming constructs. The NeuroPigPen toolkit was evaluated using 750 GB of electrophysiological signal data over a variety of Hadoop cluster configurations ranging from 3 to 30 Data nodes. The evaluation results demonstrate that the toolkit

  18. NeuroPigPen: A Scalable Toolkit for Processing Electrophysiological Signal Data in Neuroscience Applications Using Apache Pig

    PubMed Central

    Sahoo, Satya S.; Wei, Annan; Valdez, Joshua; Wang, Li; Zonjy, Bilal; Tatsuoka, Curtis; Loparo, Kenneth A.; Lhatoo, Samden D.

    2016-01-01

    The recent advances in neurological imaging and sensing technologies have led to rapid increase in the volume, rate of data generation, and variety of neuroscience data. This “neuroscience Big data” represents a significant opportunity for the biomedical research community to design experiments using data with greater timescale, large number of attributes, and statistically significant data size. The results from these new data-driven research techniques can advance our understanding of complex neurological disorders, help model long-term effects of brain injuries, and provide new insights into dynamics of brain networks. However, many existing neuroinformatics data processing and analysis tools were not built to manage large volume of data, which makes it difficult for researchers to effectively leverage this available data to advance their research. We introduce a new toolkit called NeuroPigPen that was developed using Apache Hadoop and Pig data flow language to address the challenges posed by large-scale electrophysiological signal data. NeuroPigPen is a modular toolkit that can process large volumes of electrophysiological signal data, such as Electroencephalogram (EEG), Electrocardiogram (ECG), and blood oxygen levels (SpO2), using a new distributed storage model called Cloudwave Signal Format (CSF) that supports easy partitioning and storage of signal data on commodity hardware. NeuroPigPen was developed with three design principles: (a) Scalability—the ability to efficiently process increasing volumes of data; (b) Adaptability—the toolkit can be deployed across different computing configurations; and (c) Ease of programming—the toolkit can be easily used to compose multi-step data processing pipelines using high-level programming constructs. The NeuroPigPen toolkit was evaluated using 750 GB of electrophysiological signal data over a variety of Hadoop cluster configurations ranging from 3 to 30 Data nodes. The evaluation results demonstrate that

  19. The Apache Rescue Team.

    ERIC Educational Resources Information Center

    Denali, David Line

    Experiments in using outdoor education to affect juvenile development and deter crime abound. Most of these outdoor adventure programs use a setting of developed challenges and perceived risk situations in order to create a life-changing experience. However, these "adventures" remain contrived events and require significant interpretive skills to…

  20. Community Background Reports: Three Boarding Schools (Phoenix Indian School, Phoenix, Arizona; Theodore Roosevelt School, Fort Apache, Arizona; Chemawa Indian School, Salem, Oregon). National Study of American Indian Education, Series I, No. 15, Final Report.

    ERIC Educational Resources Information Center

    Wesemann, Ralph E.; And Others

    Three Bureau of Indian Affairs off-reservation boarding schools (Phoenix Indian School in Phoenix, Arizona; Theodore Roosevelt School in Fort Apache, Arizona; and Chemawa Indian School in Salem, Oregon) are the subjects for this report, which is a part of the National Study of American Indian Education. Brief descriptions of the physical plant,…

  1. Stereotactic Body Radiation Therapy and Transarterial Chemoembolization in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

    ClinicalTrials.gov

    2016-08-19

    Child-Pugh Class A; Child-Pugh Class B; Stage IIIA Hepatocellular Carcinoma; Stage IIIB Hepatocellular Carcinoma; Stage IIIC Hepatocellular Carcinoma; Stage IVA Hepatocellular Carcinoma; Stage IVB Hepatocellular Carcinoma

  2. Tyrosinaemia II.

    PubMed

    Colditz, P B; Yu, J S; Billson, F A; Rogers, M; Molloy, H F; O'Halloran, M; Wilcken, B

    1984-08-18

    Four cases of tyrosinaemia type II (Richner-Hanhart syndrome) are reported. This syndrome consists of corneal erosions, palmar and plantar hyperkeratoses, and sometimes mental retardation. Presentation with photophobia and dendritic corneal ulceration or circumscribed palmoplantar keratoderma should alert the physician to the possible diagnosis of tyrosinaemia II. Early diagnosis is important, as the clinical picture can be modified by dietary restriction.

  3. Photosystem II

    ScienceCinema

    James Barber

    2016-07-12

    James Barber, Ernst Chain Professor of Biochemistry at Imperial College, London, gives a BSA Distinguished Lecture titled, "The Structure and Function of Photosystem II: The Water-Splitting Enzyme of Photosynthesis."

  4. Flow characteristics of streams that drain the Fort Apache and San Carlos Indian reservations, east-central Arizona, 1930-86

    USGS Publications Warehouse

    Baldys, Stanley; Bayles, J.A.

    1990-01-01

    Streamflow characteristics of the Salt River and Gila River basins in the Fort Apache and San Carlos Indian Reservations, were studied in response to pending adjudication of water resources in those basins. Statistical summaries were compiled for 28 streamflow-gaging stations in and near the reservation. Mean annual streamflow for 1930-86 was computed for stations with complete records for the period; for those stations with records that did not completely cover the 1930-86 period, record extension techniques were used. Mean annual streamflow for ungaged sites on streams with gaging stations was estimated by interpolation between data points using drainage-area ratios. Two regional-regression equations were derived to estimate mean annual streamflow at sites on ungaged natural streams. The standard error of the regression for estimation of mean annual flow for sites in the Salt River basin is -37 to +59%. The standard error of the regression for estimation of mean annual flow for sites in the Gila River basins is -18 to +21%. (USGS)

  5. The Apache Longbow-Hellfire Missile Test at Yuma Proving Ground: Introduction and Problem Formulation for a Multiple Stressor Risk Assessment

    SciTech Connect

    Efroymson, Rebecca Ann; Peterson, Mark J; Jones, Daniel Steven; Suter, Glenn

    2008-01-01

    An ecological risk assessment was conducted at Yuma Proving Ground, Arizona, as a demonstration of the Military Ecological Risk Assessment Framework (MERAF). The focus of the assessment was a testing program at Cibola Range, which involved an Apache Longbow helicopter firing Hellfire missiles at moving targets, i.e., M60-A1 tanks. The problem formulation for the assessment included conceptual models for three component activities of the test, helicopter overflight, missile firing, and tracked vehicle movement, and two ecological endpoint entities, woody desert wash communities and desert mule deer (Odocoileus hemionus crooki) populations. An activity-specific risk assessment framework was available to provide guidance for assessing risks associated with aircraft overflights. Key environmental features of the study area include barren desert pavement and tree-lined desert washes. The primary stressors associated with helicopter overflights were sound and the view of the aircraft. The primary stressor associated with Hellfire missile firing was sound. The principal stressor associated with tracked vehicle movement was soil disturbance, and a resulting, secondary stressor was hydrological change. Water loss to washes and wash vegetation was expected to result from increased ponding, infiltrationand/or evaporation associated with disturbances to desert pavement. A plan for estimating integrated risks from the three military activities was included in the problem formulation.

  6. THE TENTH DATA RELEASE OF THE SLOAN DIGITAL SKY SURVEY: FIRST SPECTROSCOPIC DATA FROM THE SDSS-III APACHE POINT OBSERVATORY GALACTIC EVOLUTION EXPERIMENT

    SciTech Connect

    Ahn, Christopher P.; Anderton, Timothy; Alexandroff, Rachael; Allende Prieto, Carlos; Anderson, Scott F.; Bhardwaj, Vaishali; Andrews, Brett H.; Aubourg, Éric; Bautista, Julian E.; Bastien, Fabienne A.; Berlind, Andreas A.; Bird, Jonathan C.; Beers, Timothy C.; Beifiori, Alessandra; Bender, Chad F.; Bizyaev, Dmitry; Blake, Cullen H.; and others

    2014-04-01

    The Sloan Digital Sky Survey (SDSS) has been in operation since 2000 April. This paper presents the Tenth Public Data Release (DR10) from its current incarnation, SDSS-III. This data release includes the first spectroscopic data from the Apache Point Observatory Galaxy Evolution Experiment (APOGEE), along with spectroscopic data from the Baryon Oscillation Spectroscopic Survey (BOSS) taken through 2012 July. The APOGEE instrument is a near-infrared R ∼ 22,500 300 fiber spectrograph covering 1.514-1.696 μm. The APOGEE survey is studying the chemical abundances and radial velocities of roughly 100,000 red giant star candidates in the bulge, bar, disk, and halo of the Milky Way. DR10 includes 178,397 spectra of 57,454 stars, each typically observed three or more times, from APOGEE. Derived quantities from these spectra (radial velocities, effective temperatures, surface gravities, and metallicities) are also included. DR10 also roughly doubles the number of BOSS spectra over those included in the Ninth Data Release. DR10 includes a total of 1,507,954 BOSS spectra comprising 927,844 galaxy spectra, 182,009 quasar spectra, and 159,327 stellar spectra selected over 6373.2 deg{sup 2}.

  7. Subsurface Analysis of the Mesaverde Group on and near the Jicarilla Apache Indian Reservation, New Mexico-its implication on Sites of Oil and Gas Accumulation

    SciTech Connect

    Ridgley, Jennie

    2001-08-21

    The purpose of the phase 2 Mesaverde study part of the Department of Energy funded project ''Analysis of oil-bearing Cretaceous Sandstone Hydrocarbon Reservoirs, exclusive of the Dakota Sandstone, on the Jicarilla Apache Indian Reservation, New Mexico'' was to define the facies of the oil-producing units within the subsurface units of the Mesaverde Group and integrate these results with outcrop studies that defined the depositional environments of these facies within a sequence stratigraphic context. The focus of this report will center on (1) integration of subsurface correlations with outcrop correlations of components of the Mesaverde, (2) application of the sequence stratigraphic model determined in the phase one study to these correlations, (3) determination of the facies distribution of the Mesaverde Group and their relationship to sites of oil and gas accumulation, (4) evaluation of the thermal maturity and potential source rocks for oil and gas in the Mesaverde Group, and (5) evaluation of the structural features on the Reservation as they may control sites of oil accumulation.

  8. SAGE II

    Atmospheric Science Data Center

    2016-02-16

    ... of stratospheric aerosols, ozone, nitrogen dioxide, water vapor and cloud occurrence by mapping vertical profiles and calculating ... (i.e. MLS and SAGE III versus HALOE) Fixed various bugs Details are in the  SAGE II V7.00 Release Notes .   ...

  9. Location, Reprocessing, and Analysis of Two Dimensional Seismic Reflection Data on the Jicarilla Apache Indian Reservation, New Mexico, Final Report, September 1, 1997-February 1, 2000

    SciTech Connect

    Ridgley, Jennie; Taylor, David J.; Huffman, Jr., A. Curtis

    2000-06-08

    Multichannel surface seismic reflection data recording is a standard industry tool used to examine various aspects of geology, especially the stratigraphic characteristics and structural style of sedimentary formations in the subsurface. With the help of the Jicarilla Apache Tribe and the Bureau of Indian Affairs we were able to locate over 800 kilometers (500 miles) of multichannel seismic reflection data located on the Jicarilla Apache Indian reservation. Most of the data was received in hardcopy form, but there were data sets where either the demultiplexed digital field data or the processed data accompanied the hardcopy sections. The seismic data was acquired from the mid 1960's to the early 1990's. The most extensive seismic coverage is in the southern part of the reservation, although there are two good surveys located on the northeastern and northwestern parts of the reservation. Most of the data show that subsurface formations are generally flat-lying in the southern and western portion of the reservation. There is, however, a significant amount of structure imaged on seismic data located over the San Juan Basin margin along the east-central and northern part of the reservation. Several west to east trending lines in these areas show a highly faulted monoclinal structure from the deep basin in the west up onto the basin margin to the east. Hydrocarbon exploration in flat lying formations is mostly stratigraphic in nature. Where there is structure in the subsurface and indications are that rocks have been folded, faulted, and fractured, exploration has concentrated on structural traps and porosity/permeability "sweet spots" caused by fracturing. Therefore, an understanding of the tectonics influencing the entire section is critical in understanding mechanisms for generating faults and fractures in the Cretaceous. It is apparent that much of the hydrocarbon production on the reservation is from fracture porosity in either source or reservoir sequences

  10. The Apache Longbow-Hellfire Missile Test at Yuma Proving Ground: Ecological Risk Assessment for Tracked Vehicle Movement across Desert Pavement

    SciTech Connect

    Peterson, Mark J; Efroymson, Rebecca Ann; Hargrove, William Walter

    2008-01-01

    A multiple stressor risk assessment was conducted at Yuma Proving Ground, Arizona, as a demonstration of the Military Ecological Risk Assessment Framework. The focus was a testing program at Cibola Range, which involved an Apache Longbow helicopter firing Hellfire missiles at moving targets, M60-A1 tanks. This paper describes the ecological risk assessment for the tracked vehicle movement component of the testing program. The principal stressor associated with tracked vehicle movement was soil disturbance, and a resulting, secondary stressor was hydrological change. Water loss to washes and wash vegetation was expected to result from increased infiltration and/or evaporation associated with disturbances to desert pavement. The simulated exposure of wash vegetation to water loss was quantified using estimates of exposed land area from a digital ortho quarter quad aerial photo and field observations, a 30 30 m digital elevation model, the flow accumulation feature of ESRI ArcInfo, and a two-step process in which runoff was estimated from direct precipitation to a land area and from water that flowed from upgradient to a land area. In all simulated scenarios, absolute water loss decreased with distance from the disturbance, downgradient in the washes; however, percentage water loss was greatest in land areas immediately downgradient of a disturbance. Potential effects on growth and survival of wash trees were quantified by using an empirical relationship derived from a local unpublished study of water infiltration rates. The risk characterization concluded that neither risk to wash vegetation growth or survival nor risk to mule deer abundance and reproduction was expected. The risk characterization was negative for both the incremental risk of the test program and the combination of the test and pretest disturbances.

  11. Performance of the Apache Point Observatory Galactic Evolution Experiment (APOGEE) high-resolution near-infrared multi-object fiber spectrograph

    NASA Astrophysics Data System (ADS)

    Wilson, John C.; Hearty, F.; Skrutskie, M. F.; Majewski, S. R.; Schiavon, R.; Eisenstein, D.; Gunn, J.; Holtzman, J.; Nidever, D.; Gillespie, B.; Weinberg, D.; Blank, B.; Henderson, C.; Smee, S.; Barkhouser, R.; Harding, A.; Hope, S.; Fitzgerald, G.; Stolberg, T.; Arns, J.; Nelson, M.; Brunner, S.; Burton, A.; Walker, E.; Lam, C.; Maseman, P.; Barr, J.; Leger, F.; Carey, L.; MacDonald, N.; Ebelke, G.; Beland, S.; Horne, T.; Young, E.; Rieke, G.; Rieke, M.; O'Brien, T.; Crane, J.; Carr, M.; Harrison, C.; Stoll, R.; Vernieri, M.; Shetrone, M.; Allende-Prieto, C.; Johnson, J.; Frinchaboy, P.; Zasowski, G.; Garcia Perez, A.; Bizyaev, D.; Cunha, K.; Smith, V. V.; Meszaros, Sz.; Zhao, B.; Hayden, M.; Chojnowski, S. D.; Andrews, B.; Loomis, C.; Owen, R.; Klaene, M.; Brinkmann, J.; Stauffer, F.; Long, D.; Jordan, W.; Holder, D.; Cope, F.; Naugle, T.; Pfaffenberger, B.; Schlegel, D.; Blanton, M.; Muna, D.; Weaver, B.; Snedden, S.; Pan, K.; Brewington, H.; Malanushenko, E.; Malanushenko, V.; Simmons, A.; Oravetz, D.; Mahadevan, S.; Halverson, S.

    2012-09-01

    The Apache Point Observatory Galactic Evolution Experiment (APOGEE) uses a dedicated 300-fiber, narrow-band near-infrared (1.51-1.7 μm), high resolution (R~22,500) spectrograph to survey approximately 100,000 giant stars across the Milky Way. This three-year survey, in operation since late-summer 2011 as part of the Sloan Digital Sky Survey III (SDSS III), will revolutionize our understanding of the kinematical and chemical enrichment histories of all Galactic stellar populations. We present the performance of the instrument from its first year in operation. The instrument is housed in a separate building adjacent to the 2.5-m SDSS telescope and fed light via approximately 45-meter fiber runs from the telescope. The instrument design includes numerous innovations including a gang connector that allows simultaneous connection of all fibers with a single plug to a telescope cartridge that positions the fibers on the sky, numerous places in the fiber train in which focal ratio degradation had to be minimized, a large mosaic-VPH (290 mm x 475 mm elliptically-shaped recorded area), an f/1.4 six-element refractive camera featuring silicon and fused silica elements with diameters as large as 393 mm, three near-infrared detectors mounted in a 1 x 3 mosaic with sub-pixel translation capability, and all of these components housed within a custom, LN2-cooled, stainless steel vacuum cryostat with dimensions 1.4-m x 2.3-m x 1.3-m.

  12. Preliminary bedrock and surficial geologic map of the west half of the Sanders 30' x 60' quadrangle, Navajo and Apache Counties, northern Arizona

    USGS Publications Warehouse

    Amoroso, Lee; Priest, Susan S.; Hiza-Redsteer, Margaret

    2014-01-01

    The bedrock and surficial geologic map of the west half of the Sanders 30' x 60' quadrangle was completed in a cooperative effort of the U.S. Geological Survey (USGS) and the Navajo Nation to provide regional geologic information for management and planning officials. This report provides baseline geologic information that will be useful in future studies of groundwater and surface water resources, geologic hazards, and the distribution of soils and plants. The west half of the Sanders quadrangle encompasses approximately 2,509 km2 (980 mi2) within Navajo and Apache Counties of northern Arizona and is bounded by lat 35°30' to 35° N., long 109°30' to 110° W. The majority of the land within the map area lies within the Navajo Nation. South of the Navajo Nation, private and State lands form a checkerboard pattern east and west of Petrified Forest National Park. In the west half of the Sanders quadrangle, Mesozoic bedrock is nearly flat lying except near folds. A shallow Cenozoic erosional basin that developed about 20 Ma in the western part of the map area cut across late Paleozoic and Mesozoic rocks that were subsequently filled with flat-lying Miocene and Pliocene mudstone and argillaceous sandstone and fluvial sediments of the Bidahochi Formation and associated volcanic rocks of the Hopi Buttes volcanic field. The Bidahochi rocks are capped by Pliocene(?) and Pleistocene fluvial sediments and Quaternary eolian and alluvial deposits. Erosion along northeast-southwest-oriented drainages have exposed elongated ridges of Bidahochi Formation and basin-fill deposits that are exposed through shallow eolian cover of similarly oriented longitudinal dunes. Stokes (1964) concluded that the accumulation of longitudinal sand bodies and the development of confined parallel drainages are simultaneous processes resulting in parallel sets of drainages and ridges oriented along the prevailing southwest wind direction on the southern Colorado Plateau.

  13. Bedrock and surficial geologic map of the Satan Butte and Greasewood 7.5’ quadrangles, Navajo and Apache Counties, northern Arizona

    USGS Publications Warehouse

    Amoroso, Lee; Priest, Susan S.; Hiza-Redsteer, Margaret

    2013-01-01

    The geologic map of the Satan Butte and Greasewood 7.5’ quadrangles is the result of a cooperative effort of the U.S. Geological Survey (USGS) and the Navajo Nation to provide regional geologic information for management and planning officials. This map provides geologic information useful for range management, plant and animal studies, flood control, water resource investigations, and natural hazards associated with sand-dune mobility. The map provides connectivity to the regional geologic framework of the Grand Canyon area of northern Arizona. The map area encompasses approximately 314 km2 (123 mi2) within Navajo and Apache Counties of northern Arizona and is bounded by lat 35°37'30" to 35°30' N., long 109°45' to 110° W. The quadrangles lie within the southern Colorado Plateau geologic province and within the northeastern portion of the Hopi Buttes (Tsézhin Bií). Large ephemeral drainages, Pueblo Colorado Wash and Steamboat Wash, originate north of the map area on the Defiance Plateau and Balakai Mesa respectively. Elevations range from 1,930 m (6,330 ft) at the top of Satan Butte to about 1,787 m (5,860 ft) at Pueblo Colorado Wash where it exits the southwest corner of the Greasewood quadrangle. The only settlement within the map area is Greasewood, Arizona, on the north side of Pueblo Colorado Wash. Navajo Highway 15 crosses both quadrangles and joins State Highway 264 northwest of Ganado. Unimproved dirt roads provide access to remote parts of the Navajo Reservation.

  14. PORT II

    NASA Technical Reports Server (NTRS)

    Muniz, Beau

    2009-01-01

    One unique project that the Prototype lab worked on was PORT I (Post-landing Orion Recovery Test). PORT is designed to test and develop the system and components needed to recover the Orion capsule once it splashes down in the ocean. PORT II is designated as a follow up to PORT I that will utilize a mock up pressure vessel that is spatially compar able to the final Orion capsule.

  15. BORE II

    2015-08-01

    Bore II, co-developed by Berkeley Lab researchers Frank Hale, Chin-Fu Tsang, and Christine Doughty, provides vital information for solving water quality and supply problems and for improving remediation of contaminated sites. Termed "hydrophysical logging," this technology is based on the concept of measuring repeated depth profiles of fluid electric conductivity in a borehole that is pumping. As fluid enters the wellbore, its distinct electric conductivity causes peaks in the conductivity log that grow and migratemore » upward with time. Analysis of the evolution of the peaks enables characterization of groundwater flow distribution more quickly, more cost effectively, and with higher resolution than ever before. Combining the unique interpretation software Bore II with advanced downhole instrumentation (the hydrophysical logging tool), the method quantifies inflow and outflow locations, their associated flow rates, and the basic water quality parameters of the associated formation waters (e.g., pH, oxidation-reduction potential, temperature). In addition, when applied in conjunction with downhole fluid sampling, Bore II makes possible a complete assessment of contaminant concentration within groundwater.« less

  16. BORE II

    SciTech Connect

    2015-08-01

    Bore II, co-developed by Berkeley Lab researchers Frank Hale, Chin-Fu Tsang, and Christine Doughty, provides vital information for solving water quality and supply problems and for improving remediation of contaminated sites. Termed "hydrophysical logging," this technology is based on the concept of measuring repeated depth profiles of fluid electric conductivity in a borehole that is pumping. As fluid enters the wellbore, its distinct electric conductivity causes peaks in the conductivity log that grow and migrate upward with time. Analysis of the evolution of the peaks enables characterization of groundwater flow distribution more quickly, more cost effectively, and with higher resolution than ever before. Combining the unique interpretation software Bore II with advanced downhole instrumentation (the hydrophysical logging tool), the method quantifies inflow and outflow locations, their associated flow rates, and the basic water quality parameters of the associated formation waters (e.g., pH, oxidation-reduction potential, temperature). In addition, when applied in conjunction with downhole fluid sampling, Bore II makes possible a complete assessment of contaminant concentration within groundwater.

  17. Big Data Approaches for the Analysis of Large-Scale fMRI Data Using Apache Spark and GPU Processing: A Demonstration on Resting-State fMRI Data from the Human Connectome Project.

    PubMed

    Boubela, Roland N; Kalcher, Klaudius; Huf, Wolfgang; Našel, Christian; Moser, Ewald

    2015-01-01

    Technologies for scalable analysis of very large datasets have emerged in the domain of internet computing, but are still rarely used in neuroimaging despite the existence of data and research questions in need of efficient computation tools especially in fMRI. In this work, we present software tools for the application of Apache Spark and Graphics Processing Units (GPUs) to neuroimaging datasets, in particular providing distributed file input for 4D NIfTI fMRI datasets in Scala for use in an Apache Spark environment. Examples for using this Big Data platform in graph analysis of fMRI datasets are shown to illustrate how processing pipelines employing it can be developed. With more tools for the convenient integration of neuroimaging file formats and typical processing steps, big data technologies could find wider endorsement in the community, leading to a range of potentially useful applications especially in view of the current collaborative creation of a wealth of large data repositories including thousands of individual fMRI datasets. PMID:26778951

  18. Big Data Approaches for the Analysis of Large-Scale fMRI Data Using Apache Spark and GPU Processing: A Demonstration on Resting-State fMRI Data from the Human Connectome Project

    PubMed Central

    Boubela, Roland N.; Kalcher, Klaudius; Huf, Wolfgang; Našel, Christian; Moser, Ewald

    2016-01-01

    Technologies for scalable analysis of very large datasets have emerged in the domain of internet computing, but are still rarely used in neuroimaging despite the existence of data and research questions in need of efficient computation tools especially in fMRI. In this work, we present software tools for the application of Apache Spark and Graphics Processing Units (GPUs) to neuroimaging datasets, in particular providing distributed file input for 4D NIfTI fMRI datasets in Scala for use in an Apache Spark environment. Examples for using this Big Data platform in graph analysis of fMRI datasets are shown to illustrate how processing pipelines employing it can be developed. With more tools for the convenient integration of neuroimaging file formats and typical processing steps, big data technologies could find wider endorsement in the community, leading to a range of potentially useful applications especially in view of the current collaborative creation of a wealth of large data repositories including thousands of individual fMRI datasets. PMID:26778951

  19. Big Data Approaches for the Analysis of Large-Scale fMRI Data Using Apache Spark and GPU Processing: A Demonstration on Resting-State fMRI Data from the Human Connectome Project.

    PubMed

    Boubela, Roland N; Kalcher, Klaudius; Huf, Wolfgang; Našel, Christian; Moser, Ewald

    2015-01-01

    Technologies for scalable analysis of very large datasets have emerged in the domain of internet computing, but are still rarely used in neuroimaging despite the existence of data and research questions in need of efficient computation tools especially in fMRI. In this work, we present software tools for the application of Apache Spark and Graphics Processing Units (GPUs) to neuroimaging datasets, in particular providing distributed file input for 4D NIfTI fMRI datasets in Scala for use in an Apache Spark environment. Examples for using this Big Data platform in graph analysis of fMRI datasets are shown to illustrate how processing pipelines employing it can be developed. With more tools for the convenient integration of neuroimaging file formats and typical processing steps, big data technologies could find wider endorsement in the community, leading to a range of potentially useful applications especially in view of the current collaborative creation of a wealth of large data repositories including thousands of individual fMRI datasets.

  20. Fungal Peritonitis: Underestimated Disease in Critically Ill Patients with Liver Cirrhosis and Spontaneous Peritonitis

    PubMed Central

    Lahmer, Tobias; Brandl, Andreas; Rasch, Sebastian; Schmid, Roland M.; Huber, Wolfgang

    2016-01-01

    Introduction Spontaneous peritonitis, especially spontaneous fungal peritonitis (SFP), is an important and potentially fatal complication in patients with endstage liver disaese. We evaluated potential risk factors, microbiological findings, and outcome of patients with SFP compared to spontaneous bacterial peritonitis (SBP) in critically ill patients. Methods Retrospective analyses of critically ill patients with suspected spontaneous peritonitis. Results Out of 205 patients, 20 (10%) had SFP, 28 (14%) had SBP, 48 (24%) had peritonitis without microbiological findings (SP) and 109 (52%) had no-peritonitis (NP). APACHE II and SOFA score were significantly higher in patients with SFP (26; 22–28; p<0.004 and 16; 14–18; p<0.002), SBP (26; 22–28; p<0.004 and 16; 14–18; p<0.002) and SP (24; 18–30; p<0.045 and 14; 10–18; p<0.044) as compared to NP (22; 16–24 and 12; 10–14). CHILD Pugh classification was mainly CHILD C and MELD Score was in patients with SFP (34; 18–40; p<0.001), SBP (32;12–40 p<0.002) and SP (29; 14–40 p<0.003) significantly higher as compared to NP (25;8–40). Nosocomial peritonitis could be significantly more often found in patients with SFP (65%; p<0.023) and SBP (62%, p<0.030) as compared to SP (51 p = 0.243) and NP (45%). Antibiotic pretreatment last 3 month prior peritonitis was significantly more often in patients with SFP (85%; p<0.002), SBP (71%, p<0.033), and SP (56; p<0.040) as compared to NP (33%). Candida albicans (60%; 12/20) was the most common isolated fungus, followed by Candida glabrata (13%) and Candida krusei (13%). Mortality rate was significantly higher in patients with SFP (90%, p<0.001), followed by SBP (75%; p<0.001) and SP (69%; p<0.001) as compared to NP (45%). Conclusion SFP is not a rare complication in end stage liver disease which is associated with increased mortality. Physicians should be aware of SFP in patients with CHILD C liver cirrhosis, elevated MELD score, antibiotic pretreatment and

  1. Sequence Stratigraphic Analysis and Facies Architecture of the Cretaceous Mancos Shale on and Near the Jicarilla Apache Indian Reservation, New Mexico-their relation to Sites of Oil Accumulation

    SciTech Connect

    Ridgley, Jennie

    2001-08-21

    The purpose of phase 1 and phase 2 of the Department of Energy funded project Analysis of oil- bearing Cretaceous Sandstone Hydrocarbon Reservoirs, exclusive of the Dakota Sandstone, on the Jicarilla Apache Indian Reservation, New Mexico was to define the facies of the oil producing units within the Mancos Shale and interpret the depositional environments of these facies within a sequence stratigraphic context. The focus of this report will center on (1) redefinition of the area and vertical extent of the ''Gallup sandstone'' or El Vado Sandstone Member of the Mancos Shale, (2) determination of the facies distribution within the ''Gallup sandstone'' and other oil-producing sandstones within the lower Mancos, placing these facies within the overall depositional history of the San Juan Basin, (3) application of the principals of sequence stratigraphy to the depositional units that comprise the Mancos Shale, and (4) evaluation of the structural features on the Reservation as they may control sites of oil accumulation.

  2. [Clinical efficacy of autologous mesenclyme multipotential stem cells transplantation in the liver cirrhosis and portal hypertension treatment].

    PubMed

    2014-09-01

    In 14 patients with cirrhosis and portal hypertention autologous mesenclyme multipotential stem cells (AMMSC) transplanation was performed in portal vein (I group, n=7) and common trunk of the hepatic artery (II group, n=6). Duration of pathological processes since diagnosis is 1-8 years (3,7±2,4 years). The initial severity was evaluated by a set of child-Pugh score: Class A - 6 (42,9%), Class B - 8 (57,1%). Cell cultures indentication and characteristics consistent with International Society of cell technology guidanes (ISCT) since 2006.   The treatment results and patients survival were determined in period 2 month - 5 years according Kaplan-Meir survival curve analysis. Morphology of liver bioptats also was performed.   It was shown that AMMSC transplantation generally positivly affects on the morpho-functional dynamics and basic hepatic syndromes. Aterial perivascular zone is the most optimal for transplantation in terms of migration, engraftment and differentiation of cells in comparison with portal field, as evidenced by the transition of some patients from class B to class A by child-Pugh score. PMID:25341236

  3. FIRE II - Cirrus Data Sets

    Atmospheric Science Data Center

    2013-07-26

    FIRE II - Cirrus Data Sets First ISCCP Regional Experiment (FIRE) II ... stratocumulus systems, the radiative properties of these clouds and their interactions. Relevant Documents:  FIRE Project Guide FIRE II - Cirrus Home Page FIRE II - Cirrus Mission Summaries ...

  4. Type II universal spacetimes

    NASA Astrophysics Data System (ADS)

    Hervik, S.; Málek, T.; Pravda, V.; Pravdová, A.

    2015-12-01

    We study type II universal metrics of the Lorentzian signature. These metrics simultaneously solve vacuum field equations of all theories of gravitation with the Lagrangian being a polynomial curvature invariant constructed from the metric, the Riemann tensor and its covariant derivatives of an arbitrary order. We provide examples of type II universal metrics for all composite number dimensions. On the other hand, we have no examples for prime number dimensions and we prove the non-existence of type II universal spacetimes in five dimensions. We also present type II vacuum solutions of selected classes of gravitational theories, such as Lovelock, quadratic and L({{Riemann}}) gravities.

  5. Angiotensin II receptor signalling.

    PubMed

    Daniels, Derek; Yee, Daniel K; Fluharty, Steven J

    2007-05-01

    Angiotensin II plays a key role in the regulation of body fluid homeostasis. To correct body fluid deficits that occur during hypovolaemia, an animal needs to ingest both water and electrolytes. Thus, it is not surprising that angiotensin II, which is synthesized in response to hypovolaemia, acts centrally to increase both water and NaCl intake. Here, we review findings relating to the properties of angiotensin II receptors that give rise to changes in behaviour. Data are described to suggest that divergent signal transduction pathways are responsible for separable behavioural responses to angiotensin II, and a hypothesis is proposed to explain how this divergence may map onto neural circuits in the brain.

  6. ANALYSIS OF OIL-BEARING CRETACEOUS SANDSTONE HYDROCARBON RESERVOIRS, EXCLUSIVE OF THE DAKOTA SANDSTONE, ON THE JICARILLA APACHE INDIAN RESERVATION, NEW MEXICO

    SciTech Connect

    Jennie Ridgley

    2000-05-21

    A goal of the Mesaverde project was to better define the depositional system of the Mesaverde in hopes that it would provide insight to new or by-passed targets for oil exploration. The new, detailed studies of the Mesaverde give us a better understanding of the lateral variability in depositional environments and facies. Recognition of this lateral variability and establishment of the criteria for separating deltaic, strandplain-barrier, and estuarine deposits from each other permit development of better hydrocarbon exploration models, because the sandstone geometry differs in each depositional system. Although these insights will provide better exploration models for gas exploration, it does not appear that they will be instrumental in finding more oil. Oil in the Mesaverde Group is produced from isolated fields on the Chaco slope; only a few wells define each field. Production is from sandstone beds in the upper part of the Point Lookout Sandstone or from individual fluvial channel sandstones in the Menefee. Stratigraphic traps rather than structural traps are more important. Source of the oil in the Menefee and Point Lookout may be from interbedded organic-rich mudstones or coals rather than from the Lewis Shale. The Lewis Shale appears to contain more type III organic matter and, hence, should produce mainly gas. Outcrop studies have not documented oil staining that might point to past oil migration through the sandstones of the Mesaverde. The lack of oil production may be related to the following: (1) lack of abundant organic matter of the type I or II variety in the Lewis Shale needed to produce oil, (2) ineffective migration pathways due to discontinuities in sandstone reservoir geometries, (3) cementation or early formation of gas prior to oil generation that reduced effective permeabilities and served as barriers to updip migration of oil, or (4) erosion of oilbearing reservoirs from the southern part of the basin. Any new production should mimic that of

  7. Ovarian Cancer Stage II

    MedlinePlus

    ... hyphen, e.g. -historical Searches are case-insensitive Ovarian Cancer Stage II Add to My Pictures View /Download : ... 1650x675 View Download Large: 3300x1350 View Download Title: Ovarian Cancer Stage II Description: Three-panel drawing of stage ...

  8. World War II Homefront.

    ERIC Educational Resources Information Center

    Garcia, Rachel

    2002-01-01

    Presents an annotated bibliography that provides Web sites focusing on the U.S. homefront during World War II. Covers various topics such as the homefront, Japanese Americans, women during World War II, posters, and African Americans. Includes lesson plan sources and a list of additional resources. (CMK)

  9. Prediction of radiation-induced liver disease by Lyman normal-tissue complication probability model in three-dimensional conformal radiation therapy for primary liver carcinoma

    SciTech Connect

    Xu ZhiYong; Liang Shixiong; Zhu Ji; Zhu Xiaodong; Zhao Jiandong; Lu Haijie; Yang Yunli; Chen Long; Wang Anyu; Fu Xiaolong; Jiang Guoliang . E-mail: jianggl@21cn.com

    2006-05-01

    Purpose: To describe the probability of RILD by application of the Lyman-Kutcher-Burman normal-tissue complication (NTCP) model for primary liver carcinoma (PLC) treated with hypofractionated three-dimensional conformal radiotherapy (3D-CRT). Methods and Materials: A total of 109 PLC patients treated by 3D-CRT were followed for RILD. Of these patients, 93 were in liver cirrhosis of Child-Pugh Grade A, and 16 were in Child-Pugh Grade B. The Michigan NTCP model was used to predict the probability of RILD, and then the modified Lyman NTCP model was generated for Child-Pugh A and Child-Pugh B patients by maximum-likelihood analysis. Results: Of all patients, 17 developed RILD in which 8 were of Child-Pugh Grade A, and 9 were of Child-Pugh Grade B. The prediction of RILD by the Michigan model was underestimated for PLC patients. The modified n, m, TD{sub 5} (1) were 1.1, 0.28, and 40.5 Gy and 0.7, 0.43, and 23 Gy for patients with Child-Pugh A and B, respectively, which yielded better estimations of RILD probability. The hepatic tolerable doses (TD{sub 5}) would be MDTNL of 21 Gy and 6 Gy, respectively, for Child-Pugh A and B patients. Conclusions: The Michigan model was probably not fit to predict RILD in PLC patients. A modified Lyman NTCP model for RILD was recommended.

  10. Multiple endocrine neoplasia (MEN) II

    MedlinePlus

    Sipple syndrome; MEN II; Pheochromocytoma - MEN II; Thyroid cancer - pheochromocytoma; Parathyroid cancer - pheochromocytoma ... The cause of MEN II is a defect in a gene called RET. This defect causes many tumors to appear in the same ...

  11. Network II Database

    1994-11-07

    The Oak Ridge National Laboratory (ORNL) Rail and Barge Network II Database is a representation of the rail and barge system of the United States. The network is derived from the Federal Rail Administration (FRA) rail database.

  12. Factor II deficiency

    MedlinePlus

    ... blood. It leads to problems with blood clotting (coagulation). Factor II is also known as prothrombin. ... blood clots form. This process is called the coagulation cascade. It involves special proteins called coagulation, or ...

  13. Tracers of Chromospheric Structure. I. Observations of Ca II K and Hα in M Dwarfs

    NASA Astrophysics Data System (ADS)

    Walkowicz, Lucianne M.; Hawley, Suzanne L.

    2009-02-01

    We report on our observing program4This paper is based on observations obtained with the Apache Point Observatory 3.5 m telescope, which is owned and operated by the Astrophysical Research Consortium. Some of the data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. to capture simultaneous spectra of Ca II and Balmer lines in a sample of nearby M3 dwarfs. Our goal is to investigate the chromospheric temperature structure required to produce these lines at the observed levels. We find a strong positive correlation between instantaneous measurements of Ca II K and the Balmer lines in active stars, although these lines may not be positively correlated in time-resolved measurements. The relationship between Hα and Ca II K remains ambiguous for weak and intermediate activity stars, with Hα absorption corresponding to a range of Ca II K emission. A similar relationship is also observed between Ca II K and the higher-order Balmer lines. As our sample consists of a single spectral type, correlations between these important chromospheric tracers cannot be ascribed to continuum effects, as suggested by other authors. These data confirm prior nonsimultaneous observations of the Hα line behavior with increasing activity, showing an initial increase in the Hα absorption with increasing Ca II K emission, prior to Hα filling in and eventually becoming a pure emission line in the most active stars. We also compare our optical measurements with archival UV and X-ray measurements, finding a positive correlation between the chromospheric and coronal emission for both high and intermediate activity stars. We compare our results with previous determinations of the active fraction of low-mass stars

  14. Carnitine palmitoyltransferase II deficiency

    PubMed Central

    Roe, C R.; Yang, B-Z; Brunengraber, H; Roe, D S.; Wallace, M; Garritson, B K.

    2008-01-01

    Background: Carnitine palmitoyltransferase II (CPT II) deficiency is an important cause of recurrent rhabdomyolysis in children and adults. Current treatment includes dietary fat restriction, with increased carbohydrate intake and exercise restriction to avoid muscle pain and rhabdomyolysis. Methods: CPT II enzyme assay, DNA mutation analysis, quantitative analysis of acylcarnitines in blood and cultured fibroblasts, urinary organic acids, the standardized 36-item Short-Form Health Status survey (SF-36) version 2, and bioelectric impedance for body fat composition. Diet treatment with triheptanoin at 30% to 35% of total daily caloric intake was used for all patients. Results: Seven patients with CPT II deficiency were studied from 7 to 61 months on the triheptanoin (anaplerotic) diet. Five had previous episodes of rhabdomyolysis requiring hospitalizations and muscle pain on exertion prior to the diet (two younger patients had not had rhabdomyolysis). While on the diet, only two patients experienced mild muscle pain with exercise. During short periods of noncompliance, two patients experienced rhabdomyolysis with exercise. None experienced rhabdomyolysis or hospitalizations while on the diet. All patients returned to normal physical activities including strenuous sports. Exercise restriction was eliminated. Previously abnormal SF-36 physical composite scores returned to normal levels that persisted for the duration of the therapy in all five symptomatic patients. Conclusions: The triheptanoin diet seems to be an effective therapy for adult-onset carnitine palmitoyltransferase II deficiency. GLOSSARY ALT = alanine aminotransferase; AST = aspartate aminotransferase; ATP = adenosine triphosphate; BHP = β-hydroxypentanoate; BKP = β-ketopentanoate; BKP-CoA = β-ketopentanoyl–coenzyme A; BUN = blood urea nitrogen; CAC = citric acid cycle; CoA = coenzyme A; CPK = creatine phosphokinase; CPT II = carnitine palmitoyltransferase II; LDL = low-density lipoprotein; MCT

  15. PEP-II Status

    SciTech Connect

    Sullivan, M.; Bertsche, K.; Browne, M.; Cai, Y.; Cheng, W.; Colocho, W.; Decker, F.-J.; Donald, M.; Ecklund, S.; Erickson, R.; Fisher, A.S.; Fox, J.; Heifets, S.; Himel, T.; Iverson, R.; Kulikov, A.; Novokhatski, A.; Pacak, V.; Pivi, M.; Rivetta, C.; Ross, M.; /SLAC /Saclay /Frascati

    2008-07-25

    PEP-II and BaBar have just finished run 7, the last run of the SLAC B-factory. PEP-II was one of the few high-current e+e- colliding accelerators and holds the present world record for stored electrons and stored positrons. It has stored 2.07 A of electrons, nearly 3 times the design current of 0.75 A and it has stored 3.21 A of positrons, 1.5 times more than the design current of 2.14 A. High-current beams require careful design of several systems. The feedback systems that control instabilities, the RF system stability loops, and especially the vacuum systems have to handle the higher power demands. We present here some of the accomplishments of the PEP-II accelerator and some of the problems we encountered while running high-current beams.

  16. About APPLE II Operation

    SciTech Connect

    Schmidt, T.; Zimoch, D.

    2007-01-19

    The operation of an APPLE II based undulator beamline with all its polarization states (linear horizontal and vertical, circular and elliptical, and continous variation of the linear vector) requires an effective description allowing an automated calculation of gap and shift parameter as function of energy and operation mode. The extension of the linear polarization range from 0 to 180 deg. requires 4 shiftable magnet arrrays, permitting use of the APU (adjustable phase undulator) concept. Studies for a pure fixed gap APPLE II for the SLS revealed surprising symmetries between circular and linear polarization modes allowing for simplified operation. A semi-analytical model covering all types of APPLE II and its implementation will be presented.

  17. About APPLE II Operation

    NASA Astrophysics Data System (ADS)

    Schmidt, T.; Zimoch, D.

    2007-01-01

    The operation of an APPLE II based undulator beamline with all its polarization states (linear horizontal and vertical, circular and elliptical, and continous variation of the linear vector) requires an effective description allowing an automated calculation of gap and shift parameter as function of energy and operation mode. The extension of the linear polarization range from 0 to 180° requires 4 shiftable magnet arrrays, permitting use of the APU (adjustable phase undulator) concept. Studies for a pure fixed gap APPLE II for the SLS revealed surprising symmetries between circular and linear polarization modes allowing for simplified operation. A semi-analytical model covering all types of APPLE II and its implementation will be presented.

  18. Mod II engine performance

    NASA Technical Reports Server (NTRS)

    Richey, Albert E.; Huang, Shyan-Cherng

    1987-01-01

    The testing of a prototype of an automotive Stirling engine, the Mod II, is discussed. The Mod II is a one-piece cast block with a V-4 single-crankshaft configuration and an annular regenerator/cooler design. The initial testing of Mod II concentrated on the basic engine, with auxiliaries driven by power sources external to the engine. The performance of the engine was tested at 720 C set temperature and 820 C tube temperature. At 720 C, it is observed that the power deficiency is speed dependent and linear, with a weak pressure dependency, and at 820 C, the power deficiency is speed and pressure dependent. The effects of buoyancy and nozzle spray pattern on the heater temperature spread are investigated. The characterization of the oil pump and the operating cycle and temperature spread tests are proposed for further evaluation of the engine.

  19. The Eutelsat II programme

    NASA Astrophysics Data System (ADS)

    Burgio, Claude; Dumesnil, Jean-Jacques

    Eutelsat II is designed to provide Europe with Ku-band communication and TV services with 16 active channels of 50 W power output. In-orbit reconfigurable antenna feed networks permit customized transmission offering either medium-gain over the whole of Europe or high-gain over tailored geographic areas, allowing TV reception on dishes as small as 60 cm. The payload design makes use of only two antennas, each comprising a dual dish reflector and two reconfigurable primary feed arrays. This paper gives an overview of the Eutelsat II mission, and presents a technical description of the satellite, the program schedule, and future prospects.

  20. SAGE II Ozone Analysis

    NASA Technical Reports Server (NTRS)

    Cunnold, Derek; Wang, Ray

    2002-01-01

    Publications from 1999-2002 describing research funded by the SAGE II contract to Dr. Cunnold and Dr. Wang are listed below. Our most recent accomplishments include a detailed analysis of the quality of SAGE II, v6.1, ozone measurements below 20 km altitude (Wang et al., 2002 and Kar et al., 2002) and an analysis of the consistency between SAGE upper stratospheric ozone trends and model predictions with emphasis on hemispheric asymmetry (Li et al., 2001). Abstracts of the 11 papers are attached.

  1. Evolution of Apache Open Source Software

    NASA Astrophysics Data System (ADS)

    Wen, Haoran; D'Souza, Raissa M.; Saul, Zachary M.; Filkov, Vladimir

    Our modern infrastructure relies increasingly on computation and computers. Accompanying this is a rise in the prevalence and complexity of computer programs. Current software systems (composed of an interacting collection of programs, functions, classes, etc.) implement a tremendous range of functionality, from simple mathematical operations to intricate control systems. Software systems are inherently extendable and tend to gain new functionality over time. Modern computers and programming languages are Turing complete and, thus, capable of implementing any computable function no matter how complex. The interdependencies between the elements of a software system form a network, and, therefore, we believe software systems can provide useful prototypic examples of how to build complex networked systems which require minimal maintenance, are robust bugs to and yet are readily extendable. Thus we ask: What makes for good design in software systems?

  2. [Angiotensin-receptor- and neprilysin-inhibition: a new option against heart failure].

    PubMed

    Bruhn, Claudia

    2016-01-01

    The molecular combination of sacubitril and valsartan (Entresto) is a new drug for reducing the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. It is usually administered in conjunction with other heart failure therapies, instead of an ACE inhibitor or an angiotensin-receptor blocker (ARB). In studies, sacubitril/ valsartan was superior to enalapril in reducing the risks of death and hospitalization for heart failure. Possible side effects of sacubitril/valsartan are hypotension, angioedema, impaired renal function and elevation in serum potassium levels. The drug should not be used in times of pregnancy and breast feeding, in patients with servere hepatic impairment (Child-Pugh C) and in combination with aliskiren in patients with diabetes. PMID:26975167

  3. College Algebra II.

    ERIC Educational Resources Information Center

    Benjamin, Carl; And Others

    Presented are student performance objectives, a student progress chart, and assignment sheets with objective and diagnostic measures for the stated performance objectives in College Algebra II. Topics covered include: differencing and complements; real numbers; factoring; fractions; linear equations; exponents and radicals; complex numbers,…

  4. Listen & Learn II.

    ERIC Educational Resources Information Center

    Community Building Resources, Spruce Grove (Alberta).

    Six community builders in Edmonton, Alberta, planned, developed, and implemented Listen and Learn II, a reflective research project in asset-based community building, over a 6-month period in 1998. They met regularly over 2 months to plan the research and design a method that was open to participation at any stage, encouraged exchange of…

  5. Instant Insanity II

    ERIC Educational Resources Information Center

    Richmond, Tom; Young, Aaron

    2013-01-01

    "Instant Insanity II" is a sliding mechanical puzzle whose solution requires the special alignment of 16 colored tiles. We count the number of solutions of the puzzle's classic challenge and show that the more difficult ultimate challenge has, up to row permutation, exactly two solutions, and further show that no…

  6. Dissecting Diversity Part II

    ERIC Educational Resources Information Center

    Matthews, Frank

    2005-01-01

    This article presents "Dissecting Diversity, Part II," the conclusion of a wide-ranging two-part roundtable discussion on diversity in higher education. The participants were as follows: Lezli Baskerville, J.D., President and CEO of the National Association for Equal Opportunity (NAFEO); Dr. Gerald E. Gipp, Executive Director of the American…

  7. Periodontics II: Course Proposal.

    ERIC Educational Resources Information Center

    Dordick, Bruce

    A proposal is presented for Periodontics II, a course offered at the Community College of Philadelphia to give the dental hygiene/assisting student an understanding of the disease states of the periodontium and their treatment. A standardized course proposal cover form is given, followed by a statement of purpose for the course, a list of major…

  8. Role of Bound Zn(II) in the CadC Cd(II)/Pb(II)/Zn(II)-Responsive Repressor

    SciTech Connect

    Kandegedara, A.; Thiyagarajan, S; Kondapalli, K; Stemmler, T; Rosen, B

    2009-01-01

    The Staphylococcus aureus plasmid pI258 cadCA operon encodes a P-type ATPase, CadA, that confers resistance to Cd(II)/Pb(II)/Zn(II). Expression is regulated by CadC, a homodimeric repressor that dissociates from the cad operator/promoter upon binding of Cd(II), Pb(II), or Zn(II). CadC is a member of the ArsR/SmtB family of metalloregulatory proteins. The crystal structure of CadC shows two types of metal binding sites, termed Site 1 and Site 2, and the homodimer has two of each. Site 1 is the physiological inducer binding site. The two Site 2 metal binding sites are formed at the dimerization interface. Site 2 is not regulatory in CadC but is regulatory in the homologue SmtB. Here the role of each site was investigated by mutagenesis. Both sites bind either Cd(II) or Zn(II). However, Site 1 has higher affinity for Cd(II) over Zn(II), and Site 2 prefers Zn(II) over Cd(II). Site 2 is not required for either derepression or dimerization. The crystal structure of the wild type with bound Zn(II) and of a mutant lacking Site 2 was compared with the SmtB structure with and without bound Zn(II). We propose that an arginine residue allows for Zn(II) regulation in SmtB and, conversely, a glycine results in a lack of regulation by Zn(II) in CadC. We propose that a glycine residue was ancestral whether the repressor binds Zn(II) at a Site 2 like CadC or has no Site 2 like the paralogous ArsR and implies that acquisition of regulatory ability in SmtB was a more recent evolutionary event.

  9. Near-infrared Spectra and Intrinsic Luminosities of Candidate Type II Quasars at 2 < z < 3.4

    NASA Astrophysics Data System (ADS)

    Greene, Jenny E.; Alexandroff, Rachael; Strauss, Michael A.; Zakamska, Nadia L.; Lang, Dustin; Liu, Guilin; Pattarakijwanich, Petchara; Hamann, Frederick; Ross, Nicholas P.; Myers, Adam D.; Brandt, W. Niel; York, Donald; Schneider, Donald P.

    2014-06-01

    We present JHK near-infrared (NIR) spectroscopy of 25 candidate Type II quasars selected from the Sloan Digital Sky Survey (SDSS), using Triplespec on the Apache Point Observatory 3.5 m telescope, the Folded-port InfraRed Echellette at the Magellan/Baade 6.5 m telescope, and the Gemini Near-Infrared Spectrograph on Gemini. At redshifts of 2 < z < 3.4, our NIR spectra probe the rest-frame optical region of these targets, which were initially selected to have strong lines of C IV and Ly α, with FWHM < 2000 km s-1 from the SDSS pipeline. We use the [O III] λ5007 line shape as a model for the narrow-line region emission and find that Hα consistently requires a broad component with FWHMs ranging from 1000 to 7500 km s-1. Interestingly, the C IV lines also require broad bases, but with considerably narrower widths of 1000-4500 km s-1. Estimating the extinction using the Balmer decrement and also the relationship in lower-z quasars between rest equivalent width and luminosity in the [O III] line, we find typical AV values of 0-2 mag, which naturally explains the attenuated C IV lines relative to Hα. We propose that our targets are moderately obscured quasars. We also describe one unusual object with three distinct velocity peaks in its [O III] spectrum.

  10. Near-infrared spectra and intrinsic luminosities of candidate type II quasars at 2 < z < 3.4

    SciTech Connect

    Greene, Jenny E.; Strauss, Michael A.; Pattarakijwanich, Petchara; Alexandroff, Rachael; Zakamska, Nadia L.; Liu, Guilin; Lang, Dustin; Hamann, Frederick; Ross, Nicholas P.; Myers, Adam D.; Brandt, W. Niel; Schneider, Donald P.; York, Donald

    2014-06-10

    We present JHK near-infrared (NIR) spectroscopy of 25 candidate Type II quasars selected from the Sloan Digital Sky Survey (SDSS), using Triplespec on the Apache Point Observatory 3.5 m telescope, the Folded-port InfraRed Echellette at the Magellan/Baade 6.5 m telescope, and the Gemini Near-Infrared Spectrograph on Gemini. At redshifts of 2 < z < 3.4, our NIR spectra probe the rest-frame optical region of these targets, which were initially selected to have strong lines of C IV and Ly α, with FWHM < 2000 km s{sup –1} from the SDSS pipeline. We use the [O III] λ5007 line shape as a model for the narrow-line region emission and find that Hα consistently requires a broad component with FWHMs ranging from 1000 to 7500 km s{sup –1}. Interestingly, the C IV lines also require broad bases, but with considerably narrower widths of 1000-4500 km s{sup –1}. Estimating the extinction using the Balmer decrement and also the relationship in lower-z quasars between rest equivalent width and luminosity in the [O III] line, we find typical A{sub V} values of 0-2 mag, which naturally explains the attenuated C IV lines relative to Hα. We propose that our targets are moderately obscured quasars. We also describe one unusual object with three distinct velocity peaks in its [O III] spectrum.

  11. SEQUENCE STRATIGRAPHIC ANALYSIS AND FACIES ARCHITECTURE OF THE CRETACEOUS MANCOS SHALE ON AND NEAR THE JICARILLA APACHE INDIAN RESERVATION, NEW MEXICO-THEIR RELATION TO SITES OF OIL ACCUMULATION

    SciTech Connect

    Jennie Ridgley

    2000-03-31

    Oil distribution in the lower part of the Mancos Shale seems to be mainly controlled by fractures and by sandier facies that are dolomite-cemented. Structure in the area of the Jicarilla Apache Indian Reservation consists of the broad northwest- to southeast-trending Chaco slope, the deep central basin, and the monocline that forms the eastern boundary of the San Juan Basin. Superimposed on the regional structure are broad low-amplitude folds. Fractures seem best developed in the areas of these folds. Using sequence stratigraphic principals, the lower part of the Mancos Shale has been subdivided into four main regressive and transgressive components. These include facies that are the basinal time equivalents to the Gallup Sandstone, an overlying interbedded sandstone and shale sequence time equivalent to the transgressive Mulatto Tongue of the Mancos Shale, the El Vado Sandstone Member which is time equivalent to part of the Dalton Sandstone, and an unnamed interbedded sandstone and shale succession time equivalent to the regressive Dalton Sandstone and transgressive Hosta Tongue of the Mesaverde Group. Facies time equivalent to the Gallup Sandstone underlie an unconformity of regional extent. These facies are gradually truncated from south to north across the Reservation. The best potential for additional oil resources in these facies is in the southern part of the Reservation where the top sandier part of these facies is preserved. The overlying unnamed wedge of transgressive rocks produces some oil but is underexplored, except for sandstones equivalent to the Tocito Sandstone. This wedge of rocks is divided into from two to five units. The highest sand content in this wedge occurs where each of the four subdivisions above the Tocito terminates to the south and is overstepped by the next youngest unit. These terminal areas should offer the best targets for future oil exploration. The El Vado Sandstone Member overlies the transgressive wedge. It produces most of

  12. Introducing CAML II

    SciTech Connect

    Pelaia II, Tom; Boyes, Matthew

    2009-01-01

    Channel Access Markup Language (CAML) is a XML based markup language and implementation for displaying EPICS channel access controls within a web browser. The CAML II project expanded upon the work of CAML I adding more features and greater integration with other web technologies. The most dramatic new feature introduced in CAML II is the introduction of a namespace so CAML controls can be embedded within XHTML documents. A repetition template with macro substitution allows for rapid coding of arbitrary XHTML repetitions. Enhancements have been made to several controls including more powerful plotting options. Advanced formatting options were introduced for text controls. Virtual process variables allow for custom calculations. An EDL to CAML translator eases the transition from EDM screens to CAML pages.

  13. RADTRAN II user guide

    SciTech Connect

    Madsen, M M; Wilmot, E L; Taylor, J M

    1983-02-01

    RADTRAN II is a flexible analytical tool for calculating both the incident-free and accident impacts of transporting radioactive materials. The consequences from incident-free shipments are apportioned among eight population subgroups and can be calculated for several transport modes. The radiological accident risk (probability times consequence summed over all postulated accidents) is calculated in terms of early fatalities, early morbidities, latent cancer fatalities, genetic effects, and economic impacts. Groundshine, inhalation, direct exposure, resuspension, and cloudshine dose pathways are modeled to calculate the radiological health risks from accidents. Economic impacts are evaluated based on costs for emergency response, cleanup, evacuation, income loss, and land use. RADTRAN II can be applied to specific scenario evaluations (individual transport modes or specified combinations), to compare alternative modes or to evaluate generic radioactive material shipments. Unit-risk factors can easily be evaluated to aid in performing generic analyses when several options must be compared with the amount of travel as the only variable.

  14. Results from SAGE II

    SciTech Connect

    Nico, J.S.

    1994-10-01

    The Russian-American Gallium solar neutrino Experiment (SAGE) began the second phase of operation (SAGE II) in September of 1992. Monthly measurements of the integral flux of solar neutrinos have been made with 55 tonnes of gallium. The K-peak results of the first nine runs of SAGE II give a capture rate of 66{sub -13}{sup +18} (stat) {sub -7}{sup +5} (sys) SNU. Combined with the SAGE I result of 73{sub -16}{sup +18} (stat) {sub -7}{sup 5} (sys) SNU, the capture rate is 69{sub -11}{sup +11} (stat) {sub -7}{sup +5} (sys) SNU. This represents only 52%--56% of the capture rate predicted by different Standard Solar Models.

  15. TARN II project

    SciTech Connect

    Katayama, T.

    1985-04-01

    On the basis of the achievement of the accelerator studies at present TARN, it is decided to construct the new ring TARN II which will be operated as an accumulator, accelerator, cooler and stretcher. It has the maximum magnetic rigidity of 7 Txm corresponding to the proton energy 1.3 GeV and the ring diameter is around 23 m. Light and heavy ions from the SF cyclotron will be injected and accelerated to the working energy where the ring will be operated as a desired mode, for example a cooler ring mode. At the cooler ring operation, the strong cooling devices such as stochastic and electron beam coolings will work together with the internal gas jet target for the precise nuclear experiments. TARN II is currently under the contruction with the schedule of completion in 1986. In this paper general features of the project are presented.

  16. Ribosomal Database Project II

    DOE Data Explorer

    The Ribosomal Database Project (RDP) provides ribosome related data and services to the scientific community, including online data analysis and aligned and annotated Bacterial small-subunit 16S rRNA sequences. As of March 2008, RDP Release 10 is available and currently (August 2009) contains 1,074,075 aligned 16S rRNA sequences. Data that can be downloaded include zipped GenBank and FASTA alignment files, a histogram (in Excel) of the number of RDP sequences spanning each base position, data in the Functional Gene Pipeline Repository, and various user submitted data. The RDP-II website also provides numerous analysis tools.[From the RDP-II home page at http://rdp.cme.msu.edu/index.jsp

  17. RISTA II trials

    NASA Astrophysics Data System (ADS)

    Martin, John R.

    1998-11-01

    Northrop Grumman Corporation has developed an advanced 2nd generation IR sensor system under the guidance of the US Army's Night Vision and Electronic Sensors Directorate (NVESD) as part of an Advanced Concept Technology Demonstration (ACTD) called Counter Mobile Rocket Launcher (CMRL). Designed to support rapid counter fire against mobile targets from an unmanned aerial vehicle (UAV), the sensor system, called reconnaissance IR surveillance target acquisition (RISTA II), consists of a 2nd generation FLIR/line scanner, a digital data link, a ground processing facility, and an aided target recognizer (AiTF). The concept of operation together with component details was reported at the passive sensors IRIS in March, 1996. The performance testing of the RISTA II System was reported at the National IRIS in November, 1997. The RISTA II sensor has subsequently undergone performance testing on a Royal Netherlands Air Force F-16 for a manned reconnaissance application in August and October, 1997, at Volkel Airbase, Netherlands. That testing showed performance compatible with the medium altitude IR sensor performance. The results of that testing, together with flight test imagery, will be presented.

  18. Definition of ACLF and inclusion criteria for extra-hepatic organ failure.

    PubMed

    Wang, Xiaojing; Sarin, Shiv Kumar; Ning, Qin

    2015-07-01

    A prominent characteristic of ACLF is rapid hepatic disease progression with subsequent extra-hepatic organ failure, manifesting as either hepatic coma or hepatorenal syndrome, which is associated with a high mortality rate in a short time. The APASL definition mainly emphasizes recognizing patients with hepatic failure. These patients may subsequently develop extra-hepatic multisystem organ failure leading to high mortality. It is therefore worthwhile to identify the short interim period between the development of liver failure and the onset of extra-hepatic organ failure, the potential therapeutic 'golden window.' Interventions during this period may prevent the development of complications and eventually change the course of the illness. Organ failure is suggested to be a central component of ACLF and may behave differently from chronic decompensated liver disease. Clear and practical criteria for the inclusion of organ failure are urgently needed so that patients with these life-threatening complications can be treated in a timely and appropriate manner. Recent studies suggested that the scoring systems evaluating organ failure [acute physiology, age and chronic health evaluation (APACHE) and sequential organ failure assessment (SOFA) scores] work better than those addressing the severity of liver disease [Child-Pugh and model of end-stage liver disease (MELD) scores] in ACLF. However, a key problem remains that the former scoring systems are reflective of organ failure and not predictive, thus limiting their value as an early indication for intervention.

  19. NSLS II Vacuum System

    SciTech Connect

    Ferreira, M.; Doom, L.; Hseuh, H.; Longo, C.; Settepani, P.; Wilson, K.; Hu, J.

    2009-09-13

    National Synchrotron Light Source II, being constructed at Brookhaven, is a 3-GeV, 500 mA, 3rd generation synchrotron radiation facility with ultra low emittance electron beams. The storage ring vacuum system has a circumference of 792 m and consists of over 250 vacuum chambers with a simulated average operating pressure of less than 1 x 10{sup -9} mbar. A summary of the update design of the vacuum system including girder supports of the chambers, gauges, vacuum pumps, bellows, beam position monitors and simulation of the average pressure will be shown. A brief description of the techniques and procedures for cleaning and mounting the chambers are given.

  20. Delta II Mars Pathfinder

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Final preparations for lift off of the DELTA II Mars Pathfinder Rocket are shown. Activities include loading the liquid oxygen, completing the construction of the Rover, and placing the Rover into the Lander. After the countdown, important visual events include the launch of the Delta Rocket, burnout and separation of the three Solid Rocket Boosters, and the main engine cutoff. The cutoff of the main engine marks the beginning of the second stage engine. After the completion of the second stage, the third stage engine ignites and then cuts off. Once the third stage engine cuts off spacecraft separation occurs.

  1. Run II luminosity progress

    SciTech Connect

    Gollwitzer, K.; /Fermilab

    2007-06-01

    The Fermilab Tevatron Collider Run II program continues at the energy and luminosity frontier of high energy particle physics. To the collider experiments CDF and D0, over 3 fb{sup -1} of integrated luminosity has been delivered to each. Upgrades and improvements in the Antiproton Source of the production and collection of antiprotons have led to increased number of particles stored in the Recycler. Electron cooling and associated improvements have help make a brighter antiproton beam at collisions. Tevatron improvements to handle the increased number of particles and the beam lifetimes have resulted in an increase in luminosity.

  2. Evaluation of the computerized procedures Manual II (COPMA II)

    SciTech Connect

    Converse, S.A.

    1995-11-01

    The purpose of this study was to evaluate the effects of a computerized procedure system, the Computerized Procedure Manual II (COPMA-II), on the performance and mental workload of licensed reactor operators. To evaluate COPMA-II, eight teams of two operators were trained to operate a scaled pressurized water reactor facility (SPWRF) with traditional paper procedures and with COPMA-II. Following training, each team operated the SPWRF under normal operating conditions with both paper procedures and COPMA-II. The teams then performed one of two accident scenarios with paper procedures, but performed the remaining accident scenario with COPMA-II. Performance measures and subjective estimates of mental workload were recorded for each performance trial. The most important finding of the study was that the operators committed only half as many errors during the accident scenarios with COPMA-II as they committed with paper procedures. However, time to initiate a procedure was fastest for paper procedures for accident scenario trials. For performance under normal operating conditions, there was no difference in time to initiate or to complete a procedure, or in the number of errors committed with paper procedures and with COPMA-II. There were no consistent differences in the mental workload ratings operators recorded for trials with paper procedures and COPMA-II.

  3. Mod II Stirling engine overviews

    NASA Technical Reports Server (NTRS)

    Farrell, Roger A.

    1988-01-01

    The Mod II engine is a second-generation automotive Stirling engine (ASE) optimized for part-power operation. It has been designed specifically to meet the fuel economy and exhaust emissions objectives of the ASE development program. The design, test experience, performance, and comparison of data to analytical performance estimates of the Mod II engine to date are reviewed. Estimates of Mod II performance in its final configuration are also given.

  4. PEP-II Alignment

    SciTech Connect

    Gaydosh, Michael

    2003-05-14

    The PEP-II Asymmetric B-factory consists of two independent storage rings, one located atop the other in the 2200m-circumference PEP tunnel. The high-energy ring, which stores a 9-GeV electron beam, is an upgrade of the existing PEP collider. It re-utilizes all of the PEP magnets and incorporates a state-of-the-art copper vacuum chamber and a new RF system capable of supporting a one-amp stored beam. The low-energy ring, which stores 3.1-GeV positrons, is new construction. Injection is achieved by extracting electrons and positrons at collision energies from the SLC and transporting them each in a dedicated bypass line. The low-emittance SLC beams will be used for the injection process.

  5. Phase II Final Report

    SciTech Connect

    Schuknecht, Nate; White, David; Hoste, Graeme

    2014-09-11

    The SkyTrough DSP will advance the state-of-the-art in parabolic troughs for utility applications, with a larger aperture, higher operating temperature, and lower cost. The goal of this project was to develop a parabolic trough collector that enables solar electricity generation in the 2020 marketplace for a 216MWe nameplate baseload power plant. This plant requires an LCOE of 9¢/kWhe, given a capacity factor of 75%, a fossil fuel limit of 15%, a fossil fuel cost of $6.75/MMBtu, $25.00/kWht thermal storage cost, and a domestic installation corresponding to Daggett, CA. The result of our optimization was a trough design of larger aperture and operating temperature than has been fielded in large, utility scale parabolic trough applications: 7.6m width x 150m SCA length (1,118m2 aperture), with four 90mm diameter × 4.7m receivers per mirror module and an operating temperature of 500°C. The results from physical modeling in the System Advisory Model indicate that, for a capacity factor of 75%: The LCOE will be 8.87¢/kWhe. SkyFuel examined the design of almost every parabolic trough component from a perspective of load and performance at aperture areas from 500 to 2,900m2. Aperture-dependent design was combined with fixed quotations for similar parts from the commercialized SkyTrough product, and established an installed cost of $130/m2 in 2020. This project was conducted in two phases. Phase I was a preliminary design, culminating in an optimum trough size and further improvement of an advanced polymeric reflective material. This phase was completed in October of 2011. Phase II has been the detailed engineering design and component testing, which culminated in the fabrication and testing of a single mirror module. Phase II is complete, and this document presents a summary of the comprehensive work.

  6. Utilizing clouds for Belle II

    NASA Astrophysics Data System (ADS)

    Sobie, R. J.

    2015-12-01

    This paper describes the use of cloud computing resources for the Belle II experiment. A number of different methods are used to exploit the private and opportunistic clouds. Clouds are making significant contributions to the generation of Belle II MC data samples and it is expected that their impact will continue to grow over the coming years.

  7. PARIS II: DESIGNING GREENER SOLVENTS

    EPA Science Inventory

    PARIS II (the program for assisting the replacement of industrial solvents, version II), developed at the USEPA, is a unique software tool that can be used for customizing the design of replacement solvents and for the formulation of new solvents. This program helps users avoid ...

  8. [Modified Class II tunnel preparation].

    PubMed

    Rimondini, L; Baroni, C

    1991-05-15

    Tunnel preparations for restoration of Class II carious lesions in primary molars preserve the marginal ridge and minimize sacrifice of healthy tooth substructure. Materials with improved bonding to tooth structure and increase potential for fluoride release allow Class II restorations without "extension for prevention". PMID:1864420

  9. Technology II: Implementation Planning Guide.

    ERIC Educational Resources Information Center

    California Community Colleges, Sacramento. Office of the Chancellor.

    The California Community Colleges (CCC) are facing a number of challenges, including the explosive use of the Internet, the digital divide, the need for integrating technology into teaching and learning, the impact of Tidal Wave II, and the need to ensure that technology is accessible to persons with disabilities. The CCCs' Technology II Strategic…

  10. ACRIM II Data and Information

    Atmospheric Science Data Center

    2015-12-30

    ACRIM II Data and Information Active Cavity Radiometer Irradiance ... and Order:   ASDC Order Tool FTP Web Access:  Data Pool Parameters:  Total Solar Irradiance ... ACRIM II Instrument Page ACRIM III Data Sets Readme Files:  Readme File Image ...

  11. Software Development at Belle II

    NASA Astrophysics Data System (ADS)

    Kuhr, Thomas; Hauth, Thomas

    2015-12-01

    Belle II is a next generation B-factory experiment that will collect 50 times more data than its predecessor Belle. This requires not only a major upgrade of the detector hardware, but also of the simulation, reconstruction, and analysis software. The challenges of the software development at Belle II and the tools and procedures to address them are reviewed in this article.

  12. National Synchrotron Light Source II

    ScienceCinema

    Steve Dierker

    2016-07-12

    The National Synchrotron Light Source II (NSLS-II) at the U.S. Department of Energy's Brookhaven National Laboratory is a proposed new state-of-the-art medium energy storage ring designed to deliver world-leading brightness and flux with top-off operation

  13. National Synchrotron Light Source II

    SciTech Connect

    Steve Dierker

    2008-03-12

    The National Synchrotron Light Source II (NSLS-II) at the U.S. Department of Energy's Brookhaven National Laboratory is a proposed new state-of-the-art medium energy storage ring designed to deliver world-leading brightness and flux with top-off operation

  14. Crystal Structure of Rat Carnitine Palmitoyltransferase II (CPT-II)

    SciTech Connect

    Hsiao,Y.; Jogl, G.; Esser, V.; Tong, L.

    2006-01-01

    Carnitine palmitoyltransferase II (CPT-II) has a crucial role in the {beta}-oxidation of long-chain fatty acids in mitochondria. We report here the crystal structure of rat CPT-II at 1.9 Angstroms resolution. The overall structure shares strong similarity to those of short- and medium-chain carnitine acyltransferases, although detailed structural differences in the active site region have a significant impact on the substrate selectivity of CPT-II. Three aliphatic chains, possibly from a detergent that is used for the crystallization, were found in the structure. Two of them are located in the carnitine and CoA binding sites, respectively. The third aliphatic chain may mimic the long-chain acyl group in the substrate of CPT-II. The binding site for this aliphatic chain does not exist in the short- and medium-chain carnitine acyltransferases, due to conformational differences among the enzymes. A unique insert in CPT-II is positioned on the surface of the enzyme, with a highly hydrophobic surface. It is likely that this surface patch mediates the association of CPT-II with the inner membrane of the mitochondria.

  15. The Stark II reality.

    PubMed

    Memel, Sherwin L; Grosvenor, John C

    2003-02-01

    The long awaited final regulations in Phase I of a two-phase rulemaking process under the Stark II law were published on January 4, 2001. The Phase I final rules govern interpretation of the Stark law as it is applied to referrals by a physician for designated categories of health services to entities in which the referring physician has a financial interest. These new regulations are of particular concern to specialists, such as orthopaedic surgeons, whose practices are oriented to ancillary services that are considered designated health services, such as radiology, physical therapy and durable medical equipment, and where the availability of clear guidance is essential to ensure that medically necessary care is provided in a manner that complies with law. However, rather than the "brightline" guidance that the healthcare community sought, the new regulations create uncertainty in areas that had not existed before. The new regulations require physicians to evaluate the full range of their business and professional relationships to avoid the risk of nonpayment of claims, civil money penalties, or program exclusion after the effective date of the new regulations. PMID:12567126

  16. Angiotensin II receptor heterogeneity

    SciTech Connect

    Herblin, W.F.; Chiu, A.T.; McCall, D.E.; Ardecky, R.J.; Carini, D.J.; Duncia, J.V.; Pease, L.J.; Wong, P.C.; Wexler, R.R.; Johnson, A.L. )

    1991-04-01

    The possibility of receptor heterogeneity in the angiotensin II (AII) system has been suggested previously, based on differences in Kd values or sensitivity to thiol reagents. One of the authors earliest indications was the frequent observation of incomplete inhibition of the binding of AII to adrenal cortical membranes. Autoradiographic studies demonstrated that all of the labeling of the rat adrenal was blocked by unlabeled AII or saralasin, but not by DuP 753. The predominant receptor in the rat adrenal cortex (80%) is sensitive to dithiothreitol (DTT) and DuP 753, and is designated AII-1. The residual sites in the adrenal cortex and almost all of the sites in the rat adrenal medulla are insensitive to both DTT and DuP 753, but were blocked by EXP655. These sites have been confirmed by ligand binding studies and are designated AII-2. The rabbit adrenal cortex is unique in yielding a nonuniform distribution of AII-2 sites around the outer layer of glomerulosa cells. In the rabbit kidney, the sites on the glomeruli are AII-1, but the sites on the kidney capsule are AII-2. Angiotensin III appears to have a higher affinity for AII-2 sites since it inhibits the binding to the rabbit kidney capsule but not the glomeruli. Elucidation of the distribution and function of these diverse sites should permit the development of more selective and specific therapeutic strategies.

  17. [Oculocutaneous type II tyrosinosis].

    PubMed

    Podglajen-Wecxsteen, O; Delaporte, E; Piette, F; le Flohic, X; Bergoend, H

    1993-01-01

    Richner-Hanhart syndrome, also called oculo-cutaneous tyrosinosis type II, is a recessive autosomal genodermatosis consecutive to a disorder of tyrosine metabolism. It presents as a varying association of palmo-plantar keratosis, bilateral keratitis and mental retardation. The authors report a new case which is atypical in that palmoplantar keratosis made a late appearance. The diagnosis was confirmed by the presence of hypertyrosinaemia, hypertyrosinuria and urinary excretion of phenolic acids, and the absence of hepato-renal lesion. Needle biopsy of the liver, which demonstrates the deficiency of soluble cytosolic tyrosine aminotransferase, is not indispensable to the diagnosis and was not performed in our patient. Treatment consisted of a dietary measure: a controlled phenylalanine and tyrosine intake to obtain a tyrosinaemia below 10 mg/100 ml. This resulted in a favourable and durable course of the oculo-cutaneous lesions. In case of isolated skin lesion, retinoids can be prescribed either alone of combined with a diet, making it less strict.

  18. Oscillator strength measurements in samarium(II), neodymium(II) and praseodymium(II)

    NASA Astrophysics Data System (ADS)

    Li, Ruohong

    A knowledge of the abundances of lanthanide ions in stellar photospheres is valuable in astrophysics, especially for chemically peculiar stars. However, the determination of elemental abundances is often limited by inadequate knowledge of oscillator strengths. Combining independently measured values of radiative lifetimes and branching fractions is an effective and precise method to measure oscillator strengths. It avoids absolute intensity measurements, requiring a knowledge of the absolute number density of particles and absolute measurements of intensity, and furthermore decreases the systematic error greatly. In the previous work of our group, the lifetimes of Sm II, Nd II and Pr II were obtained. In this thesis work, we measured the corresponding branching fractions of these lanthanide ions using a fast-ion-beam laser-induced- fluorescence technique. The power of this technique is that ions are selectively excited by a laser, which ensures that every branch comes from a single upper level and gets rid of spectral blends. Besides, the low ion-beam density ensures that the systematic errors due to collisions and radiation trapping are negligible. Combining the branching fractions with our previously measured lifetimes, we obtained 608, 430 and 260 oscillator strength values for Sm II, Nd II and Pr II transitions, respectively, over the wavelength range 350-850 nm. These transitions originate from 69 upper levels in the range 21 655 cm -1 -29 388 cm -1 for Sm II, 46 upper levels in the range 22 697 cm -1 -29 955 cm -1 for Nd II, and 32 levels in the range 22 040 cm -1 -28 577 cm -1 for Pr II. Of the 260 measured oscillator strength values of Pr II, 183 have been determined accurately for the first time. The uncertainties arise principally from systematic uncertainties of the efficiency calibration of the optical detection system (7.1%), with smaller statistical contributions (1.5%). Comparisons are made to prior measurements.

  19. Options Study - Phase II

    SciTech Connect

    R. Wigeland; T. Taiwo; M. Todosow; W. Halsey; J. Gehin

    2010-09-01

    The Options Study has been conducted for the purpose of evaluating the potential of alternative integrated nuclear fuel cycle options to favorably address the issues associated with a continuing or expanding use of nuclear power in the United States. The study produced information that can be used to inform decisions identifying potential directions for research and development on such fuel cycle options. An integrated nuclear fuel cycle option is defined in this study as including all aspects of the entire nuclear fuel cycle, from obtaining natural resources for fuel to the ultimate disposal of used nuclear fuel (UNF) or radioactive wastes. Issues such as nuclear waste management, especially the increasing inventory of used nuclear fuel, the current uncertainty about used fuel disposal, and the risk of nuclear weapons proliferation have contributed to the reluctance to expand the use of nuclear power, even though it is recognized that nuclear power is a safe and reliable method of producing electricity. In this Options Study, current, evolutionary, and revolutionary nuclear energy options were all considered, including the use of uranium and thorium, and both once-through and recycle approaches. Available information has been collected and reviewed in order to evaluate the ability of an option to clearly address the challenges associated with the current implementation and potential expansion of commercial nuclear power in the United States. This Options Study is a comprehensive consideration and review of fuel cycle and technology options, including those for disposal, and is not constrained by any limitations that may be imposed by economics, technical maturity, past policy, or speculated future conditions. This Phase II report is intended to be used in conjunction with the Phase I report, and much information in that report is not repeated here, although some information has been updated to reflect recent developments. The focus in this Options Study was to

  20. Biosatellite II mission.

    PubMed

    Reynolds, O E

    1969-01-01

    Biosatellite B was launched from Cape Kennedy, Florida, on a two-stage DELTA launch vehicle at 6:04 p.m. on 7 September, 1967. Approximately nine minutes later the 435 kg spacecraft biological laboratory was placed into a satisfactory 315 km near-circular earth orbit, successfully separated from the launch vehicle's second stage and was designated Biosatellite II. The scientific payload consisting of thirteen selected general biology and radiation experiments were subjected to planned, carefully controlled environmental conditions during 45 hours of earth-orbital flight. The decision was made to abbreviate the scheduled 3-day mission by approximately one day because of a threatening tropical storm in the recovery area, and a problem of communication with the spacecraft from the tracking stations. Highest priority was placed on recovery which was essential to obtain the scientific results on all the experiments. The operational phase of the mission came to a successful conclusion with the deorbit of the recovery capsule, deployment of the parachute system and air recovery by the United States Air Force. The 127 kg recovery capsule was returned to biology laboratories at Hickam Air Force Base, Hawaii, for disassembly and immediate inspection and analysis of the biological materials by the experimenters. It was evident immediately that the quality of the biology was excellent and this fact gave promise of a high return of scientific data. The environmental conditions provided to the experimental material in the spacecraft, provisions for experimental controls, and operational considerations are presented as they relate to interpretation of the experimental results. PMID:11949687

  1. Photosystem II: evolutionary perspectives.

    PubMed Central

    Rutherford, A W; Faller, P

    2003-01-01

    Based on the current model of its structure and function, photosystem II (PSII) seems to have evolved from an ancestor that was homodimeric in terms of its protein core and contained a special pair of chlorophylls as the photo-oxidizable cofactor. It is proposed that the key event in the evolution of PSII was a mutation that resulted in the separation of the two pigments that made up the special chlorophyll pair, making them into two chlorophylls that were neither special nor paired. These ordinary chlorophylls, along with the two adjacent monomeric chlorophylls, were very oxidizing: a property proposed to be intrinsic to monomeric chlorophylls in the environment provided by reaction centre (RC) proteins. It seems likely that other (mainly electrostatic) changes in the environments of the pigments probably tuned their redox potentials further but these changes would have been minor compared with the redox jump imposed by splitting of the special pair. This sudden increase in redox potential allowed the development of oxygen evolution. The highly oxidizing homodimeric RC would probably have been not only inefficient in terms of photochemistry and charge storage but also wasteful in terms of protein or pigments undergoing damage due to the oxidative chemistry. These problems would have constituted selective pressures in favour of the lop-sided, heterodimeric system that exists as PSII today, in which the highly oxidized species are limited to only one side of the heterodimer: the sacrificial, rapidly turned-over D1 protein. It is also suggested that one reason for maintaining an oxidizable tyrosine, TyrD, on the D2 side of the RC, is that the proton associated with its tyrosyl radical, has an electrostatic role in confining P(+) to the expendable D1 side. PMID:12594932

  2. Biosatellite II mission.

    PubMed

    Reynolds, O E

    1969-01-01

    Biosatellite B was launched from Cape Kennedy, Florida, on a two-stage DELTA launch vehicle at 6:04 p.m. on 7 September, 1967. Approximately nine minutes later the 435 kg spacecraft biological laboratory was placed into a satisfactory 315 km near-circular earth orbit, successfully separated from the launch vehicle's second stage and was designated Biosatellite II. The scientific payload consisting of thirteen selected general biology and radiation experiments were subjected to planned, carefully controlled environmental conditions during 45 hours of earth-orbital flight. The decision was made to abbreviate the scheduled 3-day mission by approximately one day because of a threatening tropical storm in the recovery area, and a problem of communication with the spacecraft from the tracking stations. Highest priority was placed on recovery which was essential to obtain the scientific results on all the experiments. The operational phase of the mission came to a successful conclusion with the deorbit of the recovery capsule, deployment of the parachute system and air recovery by the United States Air Force. The 127 kg recovery capsule was returned to biology laboratories at Hickam Air Force Base, Hawaii, for disassembly and immediate inspection and analysis of the biological materials by the experimenters. It was evident immediately that the quality of the biology was excellent and this fact gave promise of a high return of scientific data. The environmental conditions provided to the experimental material in the spacecraft, provisions for experimental controls, and operational considerations are presented as they relate to interpretation of the experimental results.

  3. Retrovirus Epidemiology Donor Study-II (REDS-II)

    ClinicalTrials.gov

    2016-04-14

    Acquired Immunodeficiency Syndrome; Blood Donors; Blood Transfusion; HIV Infections; HIV-1; HIV-2; HTLV-I; HTLV-II; Retroviridae Infections; Hepatitis, Viral, Human; Hepatitis B; Hepacivirus; West Nile Virus

  4. New instruments at IPNS: POSY II and SAD II

    SciTech Connect

    Crawford, R.K.; Felcher, G.P.; Kleb, R.; Epperson, J.E.; Thiyagarajan, P.

    1988-09-29

    Three new instruments are currently in varying degrees of development/construction at IPNS. One of these, the Glass, Liquid, and Amorphous Materials Diffractometer (GLAD) is the subject of a separate paper in these Proceedings, and so will not be discussed further here. The other two, a second neutron reflectometer (POSY II) and a second small-angle diffractometer (SAD II) are described briefly below. 5 refs., 1 fig., 1 tab.

  5. Delta II commercial space transportation

    NASA Astrophysics Data System (ADS)

    Meyers, J. F.

    1988-07-01

    Delta II is an upgraded variant of the Delta family of launch vehicles that has been in use by NASA since 1960. Among the design improvements incorporated by Delta II is a cryogenic-propellant second stage, a 2.89-m diameter satellite-protecting nose fairing, graphite/epoxy solid rocket motor cases, and 12:1 main engine expansion nozzle. The manufacturer/operator offers Delta II customers a dedicated, single satellite launch capability fully tailored to the given spacecraft's unique mission requirements.

  6. SAM II Data and Information

    Atmospheric Science Data Center

    2016-07-06

    ... Data obtained from the Stratospheric Aerosol Measurement (SAM) II instrument, which flew on board the Nimbus-7 ... Spatial Resolution:  The altitude profiles of aerosol extinction have a 1 km vertical resolution. Temporal ...

  7. The Monomeric Pentacyanocobaltate (II) Anion.

    ERIC Educational Resources Information Center

    Mosha, Donnati M. S.

    1982-01-01

    Laboratory procedures, background information, and discussion of experimental results are provided for the preparation of Thallium (I) Pentacyanocobaltate (II). The preparation of this pale green salt is carried out in an aqueous medium. (Author/JN)

  8. Pregnancy and tyrosinaemia type II.

    PubMed

    Cerone, R; Fantasia, A R; Castellano, E; Moresco, L; Schiaffino, M C; Gatti, R

    2002-08-01

    A female patient with tyrosinaemia type II is reported having undergone two untreated pregnancies. During pregnancies, plasma tyrosine was raised. The outcomes of both offspring show that maternal tyrosinaemia may have an adverse effect on the developing fetus.

  9. Annex II technical documentation assessed.

    PubMed

    van Drongelen, A W; Roszek, B; van Tienhoven, E A E; Geertsma, R E; Boumans, R T; Kraus, J J A M

    2005-12-01

    Annex II of the Medical Device Directive (MDD) is used frequently by manufacturers to obtain CE-marking. This procedure relies on a full quality assurance system and does not require an assessment of the individual medical device by a Notified Body. An investigation into the availability and the quality of technical documentation for Annex II devices revealed severe shortcomings, which are reported here. PMID:16419921

  10. Dancetime! 500 Years of Social Dance. Volume II: 20th Century. [Videotape].

    ERIC Educational Resources Information Center

    Teten, Carol

    This 50-minute VHS videotape is the second in a 2-volume series that presents 500 years of social dance, music, and fashion. It features dance and music of the 20th century, including; 1910s: animal dances, castle walk, apache, and tango; 1920s: black bottom and charleston; 1930s: marathon, movie musicals, big apple, and jitterbug; 1940s: rumba;…

  11. Synthesis and spectroscopic studies of novel Cu(II), Co(II), Ni(II) and Zn(II) mixed ligand complexes with saccharin and nicotinamide

    NASA Astrophysics Data System (ADS)

    Çakır, S.; Bulut, İ.; Naumov, P.; Biçer, E.; Çakır, O.

    2001-01-01

    Four novel mixed ligand complexes of Cu(II), Co(II), Ni(II) and Zn(II) with saccharin and nicotinamide were synthesised and characterised on the basis of elemental analysis, FT-IR spectroscopic study, UV-Vis spectrometric and magnetic susceptibility data. The structure of the Cu (II) complex is completely different from those of the Co(II), Ni(II) and Zn(II) complexes. From the frequencies of the saccharinato CO and SO 2 modes, it has been proven that the saccharinato ligands in the structure of the Cu complex are coordinated to the metal ion ([Cu(NA) 2(Sac) 2(H 2O)], where NA — nicotinamide, Sac — saccharinato ligand or ion), whilst in the Co(II), Ni(II) and Zn(II) complexes are uncoordinated and exist as ions ([M(NA) 2(H 2O) 4](Sac) 2).

  12. Real-Life Experience of Sorafenib Treatment for Hepatocellular Carcinoma in Korea: From GIDEON Data

    PubMed Central

    Kim, Do Young; Kim, Hye Jin; Han, Kwang-Hyub; Han, Sang Young; Heo, Jeong; Woo, Hyun Young; Um, Soon Ho; Kim, Yeul Hong; Kweon, Young Oh; Lim, Ho Yeong; Yoon, Jung Hwan; Lee, Wan Sik; Lee, Byung Seok; Lee, Han Chu; Ryoo, Baek-Yeol; Yoon, Seung Kew

    2016-01-01

    Purpose The purpose of this study is to report real life experiences of sorafenib therapy for hepatocellular carcinoma (HCC) in Korea, using a subset of data from GIDEON (Global Investigation of Therapeutic Decisions in HCC and of Its Treatment with Sorafenib; a large, prospective, observational study). Materials and Methods Between January 2009 and April 2012, a total of 497 patients were enrolled from 11 sites in Korea. Of these, 482 patients were evaluable for safety analyses. Case report forms of paper or electronic version were used to record safety and efficacy data from all patients. Results More patients of Child-Pugh A received sorafenib for > 8 weeks than did patients of Child-Pugh B (55.5% vs. 34.3%). Child-Pugh score did not appear to influence the starting dose of sorafenib, and approximately 70% of patients both in Child-Pugh A and B groups received the recommended initial daily dose of 800 mg (69.0% and 69.5%, respectively). The median overall survival (OS) and time to progression (TTP) were 8.5 months and 2.5 months. In Child-Pugh A patients, the median OS and TTP were 10.2 months and 2.5 months. The most frequent treatment-emergent drug-related adverse event was hand-foot skin reaction (31.7%), followed by diarrhea (18.0%). The incidence of treatment-emergent adverse events was similar in both Child-Pugh A (85.4%) and Child-Pugh B (84.8%) patients. Conclusion Sorafenib was well tolerated by Korean HCC patients in clinical settings, and the safety profile did not appear to differ by Child-Pugh status. Survival benefit in Korean patients was in line with that of a previous pivotal phase III trial (SHARP). PMID:26910470

  13. Adsorption of Cu(II), Ni(II) and Zn(II) on modified jute fibres.

    PubMed

    Shukla, S R; Pai, Roshan S

    2005-09-01

    The potential of a lignocellulosic fibre, jute, was assessed for adsorption of heavy metal ions like Cu(II), Ni(II) and Zn(II) from their aqueous solutions. The fibre was also used as adsorbent after chemically modifying it by two different techniques viz, loading of a dye with specific structure, C.I. Reactive Orange 13, and oxidising with hydrogen peroxide. Both the modified jute fibres gave higher metal ion adsorption. Thus, the dye loaded jute fibres showed metal ion uptake values of 8.4, 5.26 and 5.95 mg/g for Cu(II), Ni(II) and Zn(II), respectively, while the corresponding values for oxidised jute fibres were 7.73, 5.57 and 8.02 mg/g, as against 4.23, 3.37 and 3.55 mg/g for unmodified jute fibres. Adsorption isotherm models indicated best fit for Langmuir model for the modified jute fibres. The adsorption values decreased with lowering of pH. The desorption efficiency, regenerative and reuse capacity of these adsorbents were also assessed for three successive adsorption-desorption cycles. The adsorptive capacity was retained only when the caustic soda regeneration is carried out as an intermediate step after desorption. Possible mechanism has been given.

  14. 24 CFR 202.12 - Title II.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Title II. 202.12 Section 202.12... INSTITUTIONS AND MORTGAGEES Title I and Title II Specific Requirements § 202.12 Title II. (a) Tiered pricing—(1... mortgagee approved for participation in Title II programs is notified by the Secretary that it had a rate...

  15. EBR-II Data Digitization

    SciTech Connect

    Yoon, Su-Jong; Rabiti, Cristian; Sackett, John

    2014-08-01

    1. Objectives To produce a validation database out of those recorded signals it will be necessary also to identify the documents need to reconstruct the status of reactor at the time of the beginning of the recordings. This should comprehends the core loading specification (assemblies type and location and burn-up) along with this data the assemblies drawings and the core drawings will be identified. The first task of the project will be identify the location of the sensors, with respect the reactor plant layout, and the physical quantities recorded by the Experimental Breeder Reactor-II (EBR-II) data acquisition system. This first task will allow guiding and prioritizing the selection of drawings needed to numerically reproduce those signals. 1.1 Scopes and Deliverables The deliverables of this project are the list of sensors in EBR-II system, the identification of storing location of those sensors, identification of a core isotopic composition at the moment of the start of system recording. Information of the sensors in EBR-II reactor system was summarized from the EBR-II system design descriptions listed in Section 1.2.

  16. Proposed MIDAS II processing array

    SciTech Connect

    Meng, J.

    1982-03-01

    MIDAS (Modular Interactive Data Analysis System) is a ganged processor scheme used to interactively process large data bases occurring as a finite sequence of similar events. The existing device uses a system of eight ganged minicomputer central processor boards servicing a rotating group of 16 memory blocks. A proposal for MIDAS II, the successor to MIDAS, is to use a much larger number of ganged processors, one per memory block, avoiding the necessity of switching memories from processor to processor. To be economic, MIDAS II must use a small, relatively fast and inexpensive microprocessor, such as the TMS 9995. This paper analyzes the use of the TMS 9995 applied to the MIDAS II processing array, emphasizing computational, architectural and physical characteristics which make the use of the TMS 9995 attractive for this application.

  17. NSLS-II INJECTION CONCEPT.

    SciTech Connect

    SHAFTAN, T.; PINAYEV, I.; ROSE, J.; WANG, X.J.; ET AL.

    2005-05-16

    Currently the facility upgrade project is in progress at the NSLS (at Brookhaven National Laboratory). The goal of the NSLS-II is a 3 GeV ultra-low-emittance storage ring that will increase radiation brightness by three orders of magnitude over that of the present NSLS X-ray ring. The low emittance of the high brightness ring's lattice results in a short lifetime, so that a top-off injection mode becomes an operational necessity. Therefore, the NSLS-II injection system must provide, and efficiently inject, an electron beam at a high repetition rate. In this paper, we present our concept of the NSLS-II injection system and discuss the conditions for, and constraints on, its design.

  18. RTNS-II: present status

    SciTech Connect

    Heikkinen, D.W.; Logan, C.M.

    1980-10-01

    The present status of the RTNS-II facility is described and typical operating parameters are given. A brief discussion is given of the methods used in production of the TiT/sub 2/ targets as well as their performance and tritium handling at RTNS-II. The various types of non-interactive beam diagnostics presently in use at the neutron sources are outlined. The on-line computer system which provides a time history of an irradiation and records target performance is described. Examples are listed of several representative experimental programs which have been carried out thus far at RTNS-II. These include both active and passive experiments. Finally, several of the major improvements to the facility made since the beginning of the experimental program are given.

  19. Charm physics at CDF II

    SciTech Connect

    I. Furic

    2003-10-28

    The CDF II detector has the capability of triggering on displaced tracks. Because of this ability, CDF II has accrued large samples of charged meson decays to fully hadronic final states in 64 pb{sup -1} of p{bar p} collision data gathered at {radical}s = 1.96 TeV. Using initial Run II data samples, the production cross sections for J/{psi}, D{sup 0}, D{sup +}, D*{sup +} and D{sub s}{sup +} mesons have been measured. Ratios of branching ratios for Cabibbo suppressed final states and CP asymmetries in D{sup 0} meson decays have been studied. A measurement of the mass difference m(D{sub s}{sup +}) -m(D{sup +}) has been done, and a limit for the branching fraction of the FCNC D{sup 0} {yields} {mu}{sup +}{mu}{sup -} decays has been set.

  20. Propulsion Systems for Aircraft. Aerospace Education II. Instructional Unit II.

    ERIC Educational Resources Information Center

    Elmer, James D.

    This curriculum guide accompanies another publication in the Aerospace Education II series entitled "Propulsion Systems for Aircraft." The guide includes specific guidelines for teachers on each chapter in the textbook. Suggestions are included for objectives (traditional and behavioral), suggested outline, orientation, suggested key points,…

  1. The PEP-II design

    SciTech Connect

    Sullivan, M.K.

    1995-05-01

    The Stanford Linear Accelerator Center (SLAC), Lawrence Berkeley Laboratory (LBL), Lawrence Livermore National Laboratory (LLNL) Positron Electron Project-II (PEP-II) is a design for a high-luminosity, asymmetric energy, electron-positron colliding beam accelerator that will operate at the center-of-mass energy of the {Upsilon}4S (10.58 GeV). The goal of the design is to achieve a large enough integrated luminosity with a moving center-of-mass reference frame to he able to observe the predicted rare decay modes of the {Upsilon}4S that do not conserve charge parity (CP).

  2. Case 22:Type II diabetes

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Diabetes mellitus is characterized by elevated blood glucose levels. It is composed of two types depending on the pathogenesis. Type I diabetes is characterized by insulin deficiency and usually has its onset during childhood or teenage years. This is also called ketosis-prone diabetes. Type II diab...

  3. RARE II: The Administration's View

    ERIC Educational Resources Information Center

    Cutler, M. Rupert

    1977-01-01

    RARE II is a new Roadless Area Review and Evaluation of the National Forest system. Administrators are attempting to inventory existing wilderness areas and to determine criteria for setting aside additional ones. This information will be used for the required 1980 update of the national assessment of forests and rangelands. (MA)

  4. Type-II Weyl semimetals.

    PubMed

    Soluyanov, Alexey A; Gresch, Dominik; Wang, Zhijun; Wu, QuanSheng; Troyer, Matthias; Dai, Xi; Bernevig, B Andrei

    2015-11-26

    Fermions--elementary particles such as electrons--are classified as Dirac, Majorana or Weyl. Majorana and Weyl fermions had not been observed experimentally until the recent discovery of condensed matter systems such as topological superconductors and semimetals, in which they arise as low-energy excitations. Here we propose the existence of a previously overlooked type of Weyl fermion that emerges at the boundary between electron and hole pockets in a new phase of matter. This particle was missed by Weyl because it breaks the stringent Lorentz symmetry in high-energy physics. Lorentz invariance, however, is not present in condensed matter physics, and by generalizing the Dirac equation, we find the new type of Weyl fermion. In particular, whereas Weyl semimetals--materials hosting Weyl fermions--were previously thought to have standard Weyl points with a point-like Fermi surface (which we refer to as type-I), we discover a type-II Weyl point, which is still a protected crossing, but appears at the contact of electron and hole pockets in type-II Weyl semimetals. We predict that WTe2 is an example of a topological semimetal hosting the new particle as a low-energy excitation around such a type-II Weyl point. The existence of type-II Weyl points in WTe2 means that many of its physical properties are very different to those of standard Weyl semimetals with point-like Fermi surfaces.

  5. Recent results from DORIS II

    SciTech Connect

    Bloom, E.D.

    1985-01-01

    This report contains a brief review of recent results from the ARGUS and Crystal Ball experiments at DORIS II, concentrating on UPSILON(1S) and UPSILON(2S) spectroscopy with a short foray into ..gamma gamma.. physics. 18 refs., 10 figs.

  6. Solar Ca II K Observations

    NASA Astrophysics Data System (ADS)

    Bertello, Luca; Pevtsov, Alexei A.; Tlatov, Andrey; Singh, Jagdev

    2016-07-01

    Some of the most important archives of past and current long-term solar synoptic observations in the resonance line of Ca II K are described here. These observations are very important for understanding the state of the solar magnetism on time scales up to several decades. The first observations of this kind began in 1904 at the Kodaikanal Observatory (India), followed by similar programs at different other locations. Regular full-disk Ca II K monitoring programs started in 1915 at the Mount Wilson Observatory (USA) and in 1917 at the National Solar Observatory of Japan. Beginning in 1919 and in 1926 regular observations were taken also at the Paris-Meudon Observatory (France) and at the "Donati solar tower telescope of the Arcetri Astrophysical Observatory in Italy, respectively. In 1926 the the Astronomical Observatory of the Coimbra University in Portugal started its own program of Ca II K observations. Although some of these programs have been terminated over the years, their data archives constitute a unique resource for studies of solar variability. In the early 1970s, the National Solar Observatory (NSO) at Sacramento Peak (USA) started a new program of daily Sun-as-a-star observations in the Ca II K line. Today the NSO is continuing these observations through its Synoptic Optical Long-term Investigations of the Sun (SOLIS) facility.

  7. Tech Area II: A history

    SciTech Connect

    Ullrich, R.

    1998-07-01

    This report documents the history of the major buildings in Sandia National Laboratories` Technical Area II. It was prepared in support of the Department of Energy`s compliance with Section 106 of the National Historic Preservation Act. Technical Area II was designed and constructed in 1948 specifically for the final assembly of the non-nuclear components of nuclear weapons, and was the primary site conducting such assembly until 1952. Both the architecture and location of the oldest buildings in the area reflect their original purpose. Assembly activities continued in Area II from 1952 to 1957, but the major responsibility for this work shifted to other sites in the Atomic Energy Commission`s integrated contractor complex. Gradually, additional buildings were constructed and the original buildings were modified. After 1960, the Area`s primary purpose was the research and testing of high-explosive components for nuclear weapons. In 1994, Sandia constructed new facilities for work on high-explosive components outside of the original Area II diamond-shaped parcel. Most of the buildings in the area are vacant and Sandia has no plans to use them. They are proposed for decontamination and demolition as funding becomes available.

  8. TREC Initiative with Cheshire II.

    ERIC Educational Resources Information Center

    Larson, Ray R.

    2001-01-01

    Describes the University of California at Berkeley's participation in the TREC (Text Retrieval Conference) interactive track experiments. Highlights include results of searches on two systems, Cheshire II and ZPRISE; system design goals and implementation; precision and recall results; search questions by topic and system; and results of…

  9. 40 K Fastrac II Test

    NASA Technical Reports Server (NTRS)

    1997-01-01

    A 40 K Fastrac II duration test performed at Marshall Test Stand 116. The purpose of this test was to gauge the length of time between contact of TEA (Triethylenealuminum) and LOX (liquid oxygen) as an ignitor for the Fastrac engine.

  10. Achondrogenesis type II with polydactyly.

    PubMed

    Rittler, M; Orioli, I M

    1995-11-01

    We report on a newborn male infant who presented the typical findings of achondrogenesis type II (Langer-Saldino), and who also showed postaxial polydactyly on both feet and bilateral microtia. Polydactyly is frequently part of the short-rib syndromes, but has not been reported in achondrogenesis. The hypothesis of polydactyly as part of a contiguous gene syndrome is discussed. PMID:8588578

  11. Military Aerospace. Aerospace Education II.

    ERIC Educational Resources Information Center

    Smith, J. C.

    This book is a revised publication in the series on Aerospace Education II. It describes the employment of aerospace forces, their methods of operation, and some of the weapons and equipment used in combat and combat support activities. The first chapter describes some of the national objectives and policies served by the Air Force in peace and…

  12. Outcome in tyrosinaemia type II.

    PubMed

    Barr, D G; Kirk, J M; Laing, S C

    1991-10-01

    Tyrosinaemia type II was diagnosed in a boy with failure to thrive and in his sister on neonatal screening. On diet the outcome, at 12 and 10 years respectively, has been excellent in respect of oculocutaneous sequelae, growth, and psychomotor development, contrasting with the generally unfavourable outcome in most reported cases.

  13. Application Programming in AWIPS II

    NASA Technical Reports Server (NTRS)

    Smit, Matt; McGrath, Kevin; Burks, Jason; Carcione, Brian

    2012-01-01

    Since its inception almost 8 years ago, NASA's Short-term Prediction Research and Transition (SPoRT) Center has integrated NASA data into the National Weather Service's decision support system (DSS) the Advanced Weather Interactive Processing System (AWIPS). SPoRT has, in some instances, had to shape and transform data sets into various formats and manipulate configurations to visualize them in AWIPS. With the advent of the next generation of DSS, AWIPS II, developers will be able to develop their own plugins to handle any type of data. Raytheon is developing AWIPS II to be a more extensible package written mainly in Java, and built around a Service Oriented Architecture. A plugin architecture will allow users to install their own code modules, and (if all the rules have been properly followed) they will work hand-in-hand with AWIPS II as if it were originally built in. Users can bring in new datasets with existing plugins, tweak plugins to handle a nuance or desired new functionality, or create an entirely new visualization layout for a new dataset. SPoRT is developing plugins to ensure its existing NASA data will be ready for AWIPS II when it is delivered, and to prepare for the future of new instruments on upcoming satellites.

  14. NSLS-II RF SYSTEMS

    SciTech Connect

    Rose, J.; Gash, W.; Holub, B.; Kawashima, Y.; Ma, H.; Towne, N.; Yeddulla, M.

    2011-03-28

    The NSLS-II is a new third generation light source being constructed at Brookhaven Lab. The storage ring is optimized for low emittance by use of damping wigglers to reduce the emittance to below 1 nm-rad. The RF systems are designed to provide stable beam through tight RF phase and amplitude stability requirements.

  15. Construction of Transjugular Intrahepatic Portosystemic Shunt: Bare Metal Stent/Stent-graft Combination versus Single Stent-graft, a Prospective Randomized Controlled Study with Long-term Patency and Clinical Analysis

    PubMed Central

    Wang, Chang-Ming; Li, Xuan; Fu, Jun; Luan, Jing-Yuan; Li, Tian-Run; Zhao, Jun; Dong, Guo-Xiang

    2016-01-01

    Background: Balanced adjustment of the portal vein shunt volume during a transjugular intrahepatic portosystemic shunt (TIPS) is critical for maintaining liver perfusion and decreasing the incidence of liver insufficiency. A stent-graft is proved to be superior to a bare metal stent (BMS) for the construction of a TIPS. However, the clinical results of the combination application of stents and stent-grafts have not been determined. This study aimed to compare the technique of using a combination of stents and stent-grafts with using a single stent-graft to construct a TIPS. Methods: From April 2011 to November 2014, a total of fifty patients were randomly assigned to a stents-combination group (Group I, n = 28) or a stent-graft group (Group II, n = 22). Primary patency rates were calculated. Clinical data, including the technical success rate, bleeding control results, incidence of encephalopathy, liver function preservation, and survival rate, were assessed. Results: Technically, the success rate was 100% for both groups. The primary patency rates at 1, 2, and 3 years for Group I were 96%, 84%, and 77%, respectively; for Group II, they were 90%, 90%, and 78%, respectively. The survival rates at 1, 2, and 3 years for Group I were 79%, 74%, and 68%, respectively; for Group II, they were 82%, 82%, and 74%, respectively. The incidence of hepatic encephalopathy was 14.3% for Group I and 13.6% for Group II. The Child-Pugh score in Group I was stable at the end of the follow-up but had significantly increased in Group II (t = −2.474, P = 0.022). Conclusions: The construction of a TIPS with either the single stent-graft or BMS/stent-graft combination is effective for controlling variceal bleeding. The BMS/stent-graft combination technique is superior to the stent-graft technique in terms of hepatic function preservation indicated by the Child-Pugh score. However, considering the clinical results of the TIPS, the two techniques are comparable in their primary shunt

  16. Diversity of parasite complex II.

    PubMed

    Harada, Shigeharu; Inaoka, Daniel Ken; Ohmori, Junko; Kita, Kiyoshi

    2013-05-01

    Parasites have developed a variety of physiological functions necessary for completing at least part of their life cycles in the specialized environments of surrounding the parasites in the host. Regarding energy metabolism, which is essential for survival, parasites adapt to the low oxygen environment in mammalian hosts by using metabolic systems that are very different from those of the hosts. In many cases, the parasite employs aerobic metabolism during the free-living stage outside the host but undergoes major changes in developmental control and environmental adaptation to switch to anaerobic energy metabolism. Parasite mitochondria play diverse roles in their energy metabolism, and in recent studies of the parasitic nematode, Ascaris suum, the mitochondrial complex II plays an important role in anaerobic energy metabolism of parasites inhabiting hosts by acting as a quinol-fumarate reductase. In Trypanosomes, parasite complex II has been found to have a novel function and structure. Complex II of Trypanosoma cruzi is an unusual supramolecular complex with a heterodimeric iron-sulfur subunit and seven additional non-catalytic subunits. The enzyme shows reduced binding affinities for both substrates and inhibitors. Interestingly, this structural organization is conserved in all trypanosomatids. Since the properties of complex II differ across a wide range of parasites, this complex is a potential target for the development of new chemotherapeutic agents. In this regard, structural information on the target enzyme is essential for the molecular design of drugs. This article is part of a Special Issue entitled: Respiratory complex II: Role in cellular physiology and disease. PMID:23333273

  17. Comparative studies of aerosol extinction measurements made by the SAM II and SAGE II satellite experiments

    NASA Technical Reports Server (NTRS)

    Yue, Glenn K.; Mccormick, M. P.; Chu, W. P.; Wang, P.; Osborn, M. T.

    1989-01-01

    Results from the Stratospheric Aerosol Measurement (SAM) II and Stratospheric Aerosol and Gas Experiment (SAGE) II are compared for measurement locations which are coincident in time and space. At 1.0 micron, the SAM II and SAGE II aerosol extinction profiles are similar within their measurement errors. In addition, sunrise and sunset aerosol extinction data at four different wavelengths are compared for occasions when the SAGE II and SAM II measurements are nearly coincident in space and about 12 hours apart.

  18. Synthesis, spectroscopic, antimicrobial and DNA cleavage studies of new Co(II), Ni(II), Cu(II), Cd(II), Zn(II) and Hg(II) complexes with naphthofuran-2-carbohydrazide Schiff base

    NASA Astrophysics Data System (ADS)

    Halli, Madappa B.; Sumathi, R. B.

    2012-08-01

    A series of Co(II), Ni(II), Cu(II), Cd(II), Zn(II) and Hg(II) complexes have been synthesized with newly synthesized Schiff base derived from naphthofuran-2-carbohydrazide and cinnamaldehyde. The elemental analyses of the complexes are confined to the stoichiometry of the type MLCl2 [M = Co(II) and Cu(II)], ML2Cl2 [M = Ni(II), Cd(II), Zn(II) and Hg(II)] respectively, where L is Schiff base ligand. Structures have been proposed from elemental analyses, IR, electronic, mass, 1H NMR, ESR spectral data, magnetic, and thermal studies. The measured low molar conductance values in DMF indicate that the complexes are non-electrolytes. Spectroscopic studies suggest coordination occurs through azomethine nitrogen and carbonyl oxygen of the ligand with the metal ions. The Schiff base and its complexes have been screened for their antibacterial (Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Salmonella typhi) and antifungal (Aspergillus niger, Aspergillus flavus, Cladosporium and Candida albicans) activities by minimum inhibitory concentration (MIC) method. The DNA cleavage studies by agarose gel electrophoresis method was studied for all the complexes.

  19. Adsorption of Pb(II), Cu(II), Cd(II), Zn(II), Ni(II), Fe(II), and As(V) on bacterially produced metal sulfides.

    PubMed

    Jong, Tony; Parry, David L

    2004-07-01

    The adsorption of Pb(II), Cu(II), Cd(II), Zn(II), Ni(II), Fe(II) and As(V) onto bacterially produced metal sulfide (BPMS) material was investigated using a batch equilibrium method. It was found that the sulfide material had adsorptive properties comparable with those of other adsorbents with respect to the specific uptake of a range of metals and, the levels to which dissolved metal concentrations in solution can be reduced. The percentage of adsorption increased with increasing pH and adsorbent dose, but decreased with increasing initial dissolved metal concentration. The pH of the solution was the most important parameter controlling adsorption of Cd(II), Cu(II), Fe(II), Ni(II), Pb(II), Zn(II), and As(V) by BPMS. The adsorption data were successfully modeled using the Langmuir adsorption isotherm. Desorption experiments showed that the reversibility of adsorption was low, suggesting high-affinity adsorption governed by chemisorption. The mechanism of adsorption for the divalent metals was thought to be the formation of strong, inner-sphere complexes involving surface hydroxyl groups. However, the mechanism for the adsorption of As(V) by BPMS appears to be distinct from that of surface hydroxyl exchange. These results have important implications to the management of metal sulfide sludge produced by bacterial sulfate reduction.

  20. Solid phase extraction of lead (II), copper (II), cadmium (II) and nickel (II) using gallic acid-modified silica gel prior to determination by flame atomic absorption spectrometry.

    PubMed

    Xie, Fazhi; Lin, Xucong; Wu, Xiaoping; Xie, Zenghong

    2008-01-15

    The immobilization of gallic acid on the surface of amino group-containing silica gel phases for the formation of a newly chelating matrix (GASG) is described. The newly synthesized extractant, characterized by the diffuse reflectance infrared Fourier transformation spectroscopy and elemental analysis, was used to preconcentrate Pb(II), Cu(II), Cd(II) and Ni(II). The pH ranges for quantitative sorption and the concentrations of HCl for eluting Pb(II), Cd(II), Cu(II) and Ni(II) were opimized, respectively. The sorption capacity of the matrix has been found to be 12.63, 6.09, 15.38, 4.62mg/g for Pb(II), Cd(II), Cu(II) and Ni(II), respectively, with the preconcentration factor of approximately 200 ( approximately 100 for Cd(II)). The effects of flow rates, the eluants, the electrolytes and cations on the metal ions extraction, as well as the chelating matrix stability and reusability, were also studied. The extraction behavior of the matrix was conformed with Langmuir's equation. The present preconcentration and determination method was successfully applied to the analysis of synthetic metal mixture solution and river water samples. The 3sigma detection limit and 10sigma quantification limit for Pb(II), Cu(II), Cd(II) and Ni(II) were found to be 0.58, 0.86, 0.65, 0.92microg/L and 1.08, 1.23, 0.87, 1.26microg/L, respectively. PMID:18371717

  1. SAM II Data and Information (ASCII)

    Atmospheric Science Data Center

    2016-09-01

    SAM II (ASCII) Data and Information Data obtained from the Stratospheric Aerosol Measurement (SAM) II instrument, ... Guide Documents:  Project Guide Data Set Guide Readme Files:  Data Set (Text file) ...

  2. Type-II Quantum Computers

    NASA Astrophysics Data System (ADS)

    Yepez, Jeffrey

    This paper discusses a computing architecture that uses both classical parallelism and quantum parallelism. We consider a large parallel array of small quantum computers, connected together by classical communication channels. This kind of computer is called a type-II quantum computer, to differentiate it from a globally phase-coherent quantum computer, which is the first type of quantum computer that has received nearly exclusive attention in the literature. Although a hybrid, a type-II quantum computer retains the crucial advantage allowed by quantum mechanical superposition that its computational power grows exponentially in the number of phase-coherent qubits per node, only short-range and short time phase-coherence is needed, which significantly reduces the level of engineering facility required to achieve its construction. Therefore, the primary factor limiting its computational power is an economic one and not a technological one, since the volume of its computational medium can in principle scale indefinitely.

  3. First results from SAGE II

    SciTech Connect

    Aburashitov, J.N.; Faizov, E.L.; Gavrin, V.N.; Gusev, A.O.; Kalikhov, A.V.; Knodel, T.V.; Knyshenko, I.I.; Kornoukhov, V.N.; Mirmov, I.N.; Pshukov, A.M.; Shalagin, A.M.; Shikhin, A.A.; Timofeyev, P.V.; Veretenkin, E.P.; Vermul, V.M.; Zatsepin, G.T.; Bowles, T.J.; Nico, J.S.; Teasdale, W.A.; Wark, D.L.; Wilkerson, J.F.; Cleveland, B.T.; Daily, T.; Davis, R. Jr.; Lande, K.; Lee, C.K.; Wildenhain, P.W.; Elliott, S.R.; Cherry, M.L.

    1995-07-10

    The Russian-American Gallium solar neutrino Experiment (SAGE) began the second phase of operation (SAGE II) in September of 1992. Monthly measurements of the integral flux of solar neutrinos have been made with 55 tonnes of gallium. The K-peak results of the first five runs of SAGE II give a capture rate of 76{sup +21}{sub {minus}18}(stat){sup +5}{sub {minus}7}(sys) SNU. Combined with the SAGE I result, the capture rate is 74{sup +13}{sub {minus}12}(stat){sup +5}{sub {minus}7}(sys) SNU. This represents only 56%--60% of the capture rate predicted by different Standard Solar Models. {copyright} {ital 1995} {ital American} {ital Institute} {ital of} {ital Physics}.

  4. Belle II silicon vertex detector

    NASA Astrophysics Data System (ADS)

    Adamczyk, K.; Aihara, H.; Angelini, C.; Aziz, T.; Babu, V.; Bacher, S.; Bahinipati, S.; Barberio, E.; Baroncelli, Ti.; Baroncelli, To.; Basith, A. K.; Batignani, G.; Bauer, A.; Behera, P. K.; Bergauer, T.; Bettarini, S.; Bhuyan, B.; Bilka, T.; Bosi, F.; Bosisio, L.; Bozek, A.; Buchsteiner, F.; Casarosa, G.; Ceccanti, M.; Červenkov, D.; Chendvankar, S. R.; Dash, N.; Divekar, S. T.; Doležal, Z.; Dutta, D.; Enami, K.; Forti, F.; Friedl, M.; Hara, K.; Higuchi, T.; Horiguchi, T.; Irmler, C.; Ishikawa, A.; Jeon, H. B.; Joo, C. W.; Kandra, J.; Kang, K. H.; Kato, E.; Kawasaki, T.; Kodyš, P.; Kohriki, T.; Koike, S.; Kolwalkar, M. M.; Kvasnička, P.; Lanceri, L.; Lettenbicher, J.; Maki, M.; Mammini, P.; Mayekar, S. N.; Mohanty, G. B.; Mohanty, S.; Morii, T.; Nakamura, K. R.; Natkaniec, Z.; Negishi, K.; Nisar, N. K.; Onuki, Y.; Ostrowicz, W.; Paladino, A.; Paoloni, E.; Park, H.; Pilo, F.; Profeti, A.; Rashevskaya, I.; Rao, K. K.; Rizzo, G.; Rozanska, M.; Sandilya, S.; Sasaki, J.; Sato, N.; Schultschik, S.; Schwanda, C.; Seino, Y.; Shimizu, N.; Stypula, J.; Suzuki, J.; Tanaka, S.; Tanida, K.; Taylor, G. N.; Thalmeier, R.; Thomas, R.; Tsuboyama, T.; Uozumi, S.; Urquijo, P.; Vitale, L.; Volpi, M.; Watanuki, S.; Watson, I. J.; Webb, J.; Wiechczynski, J.; Williams, S.; Würkner, B.; Yamamoto, H.; Yin, H.; Yoshinobu, T.

    2016-09-01

    The Belle II experiment at the SuperKEKB collider in Japan is designed to indirectly probe new physics using approximately 50 times the data recorded by its predecessor. An accurate determination of the decay-point position of subatomic particles such as beauty and charm hadrons as well as a precise measurement of low-momentum charged particles will play a key role in this pursuit. These will be accomplished by an inner tracking device comprising two layers of pixelated silicon detector and four layers of silicon vertex detector based on double-sided microstrip sensors. We describe herein the design, prototyping and construction efforts of the Belle-II silicon vertex detector.

  5. [Tyrosinemia type II. Case report].

    PubMed

    Benatiya, A I; Bouayed, M A; Touiza, E; Daoudi, K; Bhalil, S; Elmesbahi, I; Tahri, H

    2005-01-01

    Tyrosinemia type II or Richner-Hanhart syndrome is a rare hereditary disease characterized by the association of pseudoherpetiform corneal ulcerations and palmoplantar hyperkeratosis. We report the case of a 12 year-old young man presenting a superficial punctate keratitis and a corneal dystrophy in both eyes, associated with a palmoplantar hyperkeratosis. The dosage of the serum level of tyrosine is meaningfully raised to 1236 micromol/l. A dietary treatment restraining tyrosine and phenylalanine is started with favorable results after an evolution of 6 months. Tyrosinemia type II is an autosomal recessive disease, due to an enzymatic deficit in tyrosine aminotransferase. The diagnosis is based on the clinic and high level of serum and urinary tyrosine as well as of its urinary metabolites. This disease must be suspected in all cases of dentritic keratitis not reacting on the antiviral treatment, and more especially if it is associated with cutaneous lesions such as palmo-plantar keratosis.

  6. Jefferson Lab's Trim Card II

    SciTech Connect

    Trent Allison; Sarin Philip; C. Higgins; Edward Martin; William Merz

    2005-05-01

    Jefferson Lab's Continuous Electron Beam Accelerator Facility (CEBAF) uses Trim Card I power supplies to drive approximately 1900 correction magnets. These trim cards have had a long and illustrious service record. However, some of the employed technology is now obsolete, making it difficult to maintain the system and retain adequate spares. The Trim Card II is being developed to act as a transparent replacement for its aging predecessor. A modular approach has been taken in its development to facilitate the substitution of sections for future improvements and maintenance. The resulting design has been divided into a motherboard and 7 daughter cards which has also allowed for parallel development. The Trim Card II utilizes modern technologies such as a Field Programmable Gate Array (FPGA) and a microprocessor to embed trim card controls and diagnostics. These reprogrammable devices also provide the versatility to incorporate future requirements.

  7. Blebbistatin and blebbistatin-inactivated myosin II inhibit myosin II-independent processes in Dictyostelium

    PubMed Central

    Shu, Shi; Liu, Xiong; Korn, Edward D.

    2005-01-01

    Blebbistatin, a cell-permeable inhibitor of class-II myosins, was developed to provide a tool for studying the biologic roles of myosin II. Consistent with this use, we find that blebbistatin inhibits three myosin II-dependent processes in Dictyostelium (growth in suspension culture, capping of Con A receptors, and development to fruiting bodies) and does not inhibit growth on plates, which does not require myosin II. As expected, macropinocytosis (myosin I-dependent), contractile vacuole activity (myosin V-dependent), and phagocytosis (myosin VII-dependent), none of which requires myosin II, are not inhibited by blebbistatin in myosin II-null cells, but, unexpectedly, blebbistatin does inhibit macropinocytosis and phagocytosis by cells expressing myosin II. Expression of catalytically inactive myosin II in myosin II-null cells also inhibits macropinocytosis and phagocytosis. Both blebbistatin-inhibited myosin II and catalytically inactive myosin II form cytoplasmic aggregates, which may be why they inhibit myosin II-independent processes, but neither affects the distribution of actin filaments in vegetative cells or actin and myosin distribution in dividing or polarized cells. Blebbistatin also inhibits cell streaming and plaque expansion in myosin II-null cells. Our results are consistent with myosin II being the only Dictyostelium myosin that is inhibited by blebbistatin but also show that blebbistatin-inactivated myosin II inhibits some myosin II-independent processes and that blebbistatin inhibits other activities in the absence of myosin II. PMID:15671182

  8. MPS II drift chamber system

    SciTech Connect

    Platner, E.D.

    1982-01-01

    The MPS II detectors are narrow drift space chambers designed for high position resolution in a magnetic field and in a very high particle flux environment. Central to this implementation was the development of 3 multi-channel custom IC's and one multi-channel hybrid. The system is deadtimeless and requires no corrections on an anode-to-anode basis. Operational experience and relevance to ISABELLE detectors is discussed.

  9. Light echoes - Type II supernovae

    NASA Technical Reports Server (NTRS)

    Schaefer, Bradley E.

    1987-01-01

    Type II supernovae (SNs) light curves show a remarkable range of shapes. Data have been collected for the 12 Type II SNs that have light curve information for more than four months past maximum. Contrary to previous reports, it is found that (1) the decay rate after 100 days past maximum varies by almost an order of magnitude and (2) the light curve shapes are not bimodally distributed, but actually form a continuum. In addition, it is found that the extinctions to the SNs are related to the light curve shapes. This implies that the absorbing dust is local to the SNs. The dust is likely to be part of a circumstellar shell emitted by the SN progenitor that Dwek (1983) has used to explain infrared echoes. The optical depth of the shell can get quite large. In such cases, it is found that the photons scattered and delayed by reflection off dust grains will dominate the light curve several months after peak brightness. This 'light echo' offers a straightforward explanation of the diversity of Type II SN light curves.

  10. Topaz II preliminary safety assessment

    SciTech Connect

    Marshall, A.C. ); Standley, V. ); Voss, S.S. ); Haskin, E. )

    1993-01-10

    The Strategic Defense Initiative Organization (SDIO) decided to investigate the possibility of launching a Russian Topaz II space nuclear power system. A preliminary safety assessment was conducted to determine whether or not a space mission could be conducted safely and within budget constraints. As part of this assessment, a safety policy and safety functional requirements were developed to guide both the safety assessment and future Topaz II activities. A review of the Russian flight safety program was conducted and documented. Our preliminary safety assessment included a top level event tree, neutronic analysis of normal and accident configurations, an evaluation of temperature coefficients of reactivity, a reentry and disposal analysis, and analysis of postulated launch abort impact accidents, and an analysis of postulated propellant fire and explosion accidents. Based on the assessment, it appears that it will be possible to safely launch the Topaz II system in the U.S. with some possible system modifications. The principal system modifications will probably include design changes to preclude water flooded criticality and to assure intact reentry.

  11. PEP-II Operations Report

    SciTech Connect

    Zisman, Michael S.

    2000-11-01

    PEP-II is a two-ring asymmetric B factory operating at the Upsilon(4S) resonance. It was constructed by a SLAC-LBNL-LLNL collaboration. The collider comprises two rings, a High-Energy Ring (HER) storing 9 GeV electrons, and a Low-Energy Ring (LER) storing 3.1 GeV positrons. Commissioning of the HER began in mid-1997 and commissioning of the LER began in mid-1998. First evidence for collisions was obtained on July 23, 1998. The BaBar detector was installed in early 1999, and commissioning with the detector commenced in May 1999. By September 1999, PEP-II had reached a peak luminosity of 1.35 x 10{sup 33} cm{sup {minus}2} s{sup {minus}1}. In the present run, which began in October 1999, the peak luminosity has reached 3.1 x 10{sup 33} cm{sup {minus}2} s{sup {minus}1} and the integrated luminosity delivered is 25 fb{sup {minus}1}. At present, PEP-II is the world's highest luminosity collider. In this paper we describe the startup experience and summarize the operational experience during fiscal year 2000 (from October 1999 through September 2000). Plan s for luminosity upgrades are briefly described.

  12. Argus II retinal prosthesis system: An update.

    PubMed

    Rachitskaya, Aleksandra V; Yuan, Alex

    2016-09-01

    This review focuses on a description of the Argus II retinal prosthesis system (Argus II; Second Sight Medical Products, Sylmar, CA) that was approved for humanitarian use by the FDA in 2013 in patients with retinitis pigmentosa with bare or no light perception vision. The article describes the components of Argus II, the studies on the implant, and future directions. PMID:26855177

  13. Spectroscopic and mycological studies of Co(II), Ni(II) and Cu(II) complexes with 4-aminoantipyrine derivative

    NASA Astrophysics Data System (ADS)

    Sharma, Amit Kumar; Chandra, Sulekh

    2011-10-01

    Complexes of the type [M(L)X 2], where M = Co(II), Ni(II) and Cu(II), have been synthesized with novel NO-donor Schiff's base ligand, 1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one) which is obtained by the acid catalyzed condensation of 1,4-diformylpiperazine with 4-aminoantipyrine. The elemental analyses, molar conductance measurements, magnetic susceptibility measurements, IR, UV, NMR, mass and EPR studies of the compounds led to the conclusion that the ligand acts as tetradentate chelate. The Schiff's base ligand forms hexacoordinated complexes having octahedral geometry for Ni(II) and tetragonal geometry for Co(II) and Cu(II) complexes. The mycological studies of the compounds were examined against the several opportunistic pathogens, i.e., Alternaria brassicae, Aspergillus niger and Fusarium oxysporum. The Cu(II) complexes were found to have most fungicidal behavior.

  14. 40 CFR Table II-1 to Subpart II of... - Emission Factors

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Emission Factors II Table II-1 to Subpart II of Part 98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Industrial Wastewater Treatment Pt. 98, Subpt. II, Table...

  15. 40 CFR Table II-1 to Subpart II of... - Emission Factors

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Emission Factors II Table II-1 to Subpart II of Part 98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Industrial Wastewater Treatment Pt. 98, Subpt. II, Table...

  16. Synthesis, spectral characterization and biological evaluation of Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) complexes with thiosemicarbazone ending by pyrazole and pyridyl rings

    NASA Astrophysics Data System (ADS)

    Yousef, T. A.; Abu El-Reash, G. M.; Al-Jahdali, M.; El-Rakhawy, El-Bastawesy R.

    2014-08-01

    Here we present the synthesis of the new Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) complexes with chelating ligand (Z)-(2-((1,3-diphenyl-1H-pyrazol-4-yl)methylene) hydrazinyl)(pyridin-2-ylamino)methanethiol. All the complexes were characterized by elemental analysis, IR, 1H NMR, UV-vis, magnetic susceptibility measurements and EPR spectral studies. IR spectra of complexes showed that the ligand behaves as NN neutral bidentate, NSN mononegative tridentate and NSNN mononegative tetradentate. The electronic spectra and the magnetic measurements suggested the octahedral geometry for all complexes as well as the EPR confirmed the tetragonal distorted octahedral for Cu(II) complex. Cd(II) complex showed the highest inhibitory antioxidant activity either using ABTS method. The SOD-like activity exhibited those Cd(II) and Zn(II) complexes have strong antioxidative properties. We tested the synthesized compounds for antitumor activity and showed that the ability to kill liver (HePG2) and breast (MCF-7) cancer cells definitely.

  17. Zeeman effect of As II.

    NASA Technical Reports Server (NTRS)

    Li, H.; Andrew, K. L.

    1972-01-01

    Spectrograms of As electrodeless-discharge tubes operated in a field of 24,025 G have given Zeeman patterns for 232 As II spectral lines from 2361 to 10,556 A and yielded 80 Lande g factors, of which more than half are new. There is agreement between these and the g values calculated by least-squares fitting for single configurations or for multiconfigurations, where configuration interaction is noticeable. All of the measured g values as well as the energy levels are used in the fitting process.

  18. Commissioning of NSLS-II

    SciTech Connect

    Willeke, F.

    2015-05-03

    NSLS-II, the new 3rd generation light source at BNL was designed for a brightness of 1022 photons s-1mm-2mrad-2 (0.1%BW)-1. It was constructed between 2009 and 2014. The storage ring was commissioned in April 2014 which was followed by insertion device and beamline commissioning in the fall of 2014. All ambitious design parameters of the facility have already been achieved except for commissioning the full beam intensity of 500mA which requires more RF installation. This paper reports on the results of commissioning.

  19. Shuttle II - The next generation

    NASA Astrophysics Data System (ADS)

    Eldred, C. H.

    1986-01-01

    A comparative evaluation is conducted for next-generation Space Shuttle-type system configurations, in light of mission and design goals, performance and operational requirements, and technology development needs and opportunities. Cargo vehicle options presently entertained are an unmanned Shuttle Derivative Vehicle and a Heavy Lift Launch Vehicle. Two high priority manned vehicle options are small (35,000-lb payload) and large (150,000-lb payload) fully reusable vehicles. Attention is given to single stage vs. two-stage 'Shuttle II' system performance and economic projections.

  20. Mass spectrometry and potentiometry studies of Pb(II)-, Cd(II)- and Zn(II)-cystine complexes.

    PubMed

    Furia, Emilia; Aiello, Donatella; Di Donna, Leonardo; Mazzotti, Fabio; Tagarelli, Antonio; Thangavel, Hariprasad; Napoli, Anna; Sindona, Giovanni

    2014-01-21

    Cd(II)-, Pb(II)- and Zn(II)-cystine complexes were investigated by potentiometric and different mass spectrometric (MS) methodologies. Laser desorption mass spectrometry has provided both the composition and structure of metal-cystine complexes according to the speciation models proposed on the basis of the potentiometric data. Detection of neutral complexes was achieved by protonation or electrochemical reduction during mass spectrometric experiments. The redox activity of metal-cystine complexes was confirmed by laser desorption and charge transfer matrix assisted laser assisted MS experiments, which allowed us to observe the formation of complexes with a reduction of cystine. The stoichiometry of Cd(II)-, Pb(II)- and Zn(II)-cystine complexes was defined by observing the isotopic pattern of the investigated compound. The results suggest that interaction occurs through the carboxylate group of the ligand.

  1. Spectral studies on cobalt(II), nickel(II) and copper(II) complexes of naphthaldehyde substituted aroylhydrazones.

    PubMed

    Singh, Pramod Kumar; Kumar, Deo Nandan

    2006-07-01

    A series of new coordination complexes of cobalt(II), nickel(II) and copper(II) with two new aroylhydrazones, 2-hydroxy-1-naphthaldehyde isonicotinoylhydrazone (H(2)L(1)) and 2-hydroxy-1-naphthaldehyde-2-thenoyl-hydrazone (H(2)L(2)) have been synthesized and characterized by elemental analysis, conductance measurements, magnetic susceptibility measurements, (1)H NMR spectroscopy, IR spectroscopy, electronic spectroscopy, EPR spectroscopy and thermal analysis. IR spectra suggests ligands acts as a tridentate dibasic donor coordinating through the deprotonated naphtholic oxygen atom, azomethine nitrogen atom and enolic oxygen atom. EPR and ligand field spectra suggests octahedral geometry for Co(II) and Ni(II) complexes and a square planar geometry for Cu(II) complexes. PMID:16529995

  2. Spectral studies on cobalt(II), nickel(II) and copper(II) complexes of naphthaldehyde substituted aroylhydrazones

    NASA Astrophysics Data System (ADS)

    Singh, Pramod Kumar; Kumar, Deo Nandan

    2006-07-01

    A series of new coordination complexes of cobalt(II), nickel(II) and copper(II) with two new aroylhydrazones, 2-hydroxy-1-naphthaldehyde isonicotinoylhydrazone (H 2L 1) and 2-hydroxy-1-naphthaldehyde-2-thenoyl-hydrazone (H 2L 2) have been synthesized and characterized by elemental analysis, conductance measurements, magnetic susceptibility measurements, 1H NMR spectroscopy, IR spectroscopy, electronic spectroscopy, EPR spectroscopy and thermal analysis. IR spectra suggests ligands acts as a tridentate dibasic donor coordinating through the deprotonated naphtholic oxygen atom, azomethine nitrogen atom and enolic oxygen atom. EPR and ligand field spectra suggests octahedral geometry for Co(II) and Ni(II) complexes and a square planar geometry for Cu(II) complexes.

  3. Topaz II preliminary safety assessment

    SciTech Connect

    Marshall, A.C. ); Standley, V. ); Voss, S.S. ); Haskin, E. . Dept. of Chemical and Nuclear Engineering)

    1992-01-01

    The Strategic Defense Initiative Organization (SDIO) decided to investigate the possibility of launching a Russian Topaz 11 space nuclear power system. A preliminary safety assessment was conducted to determine whether or not a space mission could be conducted safely and within budget constraints. As part of this assessment, a safety policy and safety functional requirements were developed to guide both the safely assessment and future Topaz II activities. A review of the Russian flight safety program was conducted and documented. Our preliminary safety assessment included a top level event tree, neutronic analysis of normal and accident configurations, an evaluation of temperature coefficients of reactivity, a reentry and disposal analysis, and analysis of postulated launch abort impact accidents, and an analysis of postulated propellant fire and explosion accidents. Based on the assessment, it appears that it will be possible to safely launch the Topaz II system in the US with some possible system modifications. The principal system modifications will probably include design changes to preclude water flooded criticality and to assure intact reentry.

  4. The SRC-II process

    NASA Astrophysics Data System (ADS)

    Schmid, B. K.; Jackson, D. M.

    1981-03-01

    The Solvent Refined Coal (SRC-II) process which produces low-sulfur distillate fuel oil from coal is discussed. The process dissolves coal in a process-derived solvent at elevated temperature and pressure in the presence of hydrogen, separates the undissolved mineral residue, then recovers the original solvent by vacuum distillation. The distillate fuel oil produced is for use largely as a nonpolluting fuel for generating electrical power and steam and is expected to be competitive with petroleum fuels during the 1980s. During this period, the SRC-II fuel oil is expected to be attractive compared with combustion of coal with flue gas desulfurization in U.S. East Coast oil-burning power plants, as well as in small and medium-sized industrial boilers. The substantial quantities of methane, light hydrocarbons and naphtha produced by the process have value as feedstocks for preparation of pipeline gas, ethylene and high-octane unleaded gasoline, and can replace petroleum fractions in many applications. The liquid and gas products from a future large-scale plant, such as the 6000 t/day plant planned for Morgantown, West Virginia, are expected to have an overall selling price of $4.25 to $4.75/GJ.

  5. BNL ATF II beamlines design

    SciTech Connect

    Fedurin, M.; Jing, Y.; Stratakis, D.; Swinson, C.

    2015-05-03

    The Brookhaven National Laboratory. Accelerator Test Facility (BNL ATF) is currently undergoing a major upgrade (ATF-II). Together with a new location and much improved facilities, the ATF will see an upgrade in its major capabilities: electron beam energy and quality and CO2 laser power. The electron beam energy will be increased in stages, first to 100-150 MeV followed by a further increase to 500 MeV. Combined with the planned increase in CO2 laser power (from 1-100 TW), the ATF-II will be a powerful tool for Advanced Accelerator research. A high-brightness electron beam, produced by a photocathode gun, will be accelerated and optionally delivered to multiple beamlines. Besides the energy range (up to a possible 500 MeV in the final stage) the electron beam can be tailored to each experiment with options such as: small transverse beam size (<10 um), short bunch length (<100 fsec) and, combined short and small bunch options. This report gives a detailed overview of the ATFII capabilities and beamlines configuration.

  6. THE SPECTRUM OF Fe II

    SciTech Connect

    Nave, Gillian; Johansson, Sveneric

    2013-01-15

    The spectrum of singly ionized iron (Fe II) has been recorded using high-resolution Fourier transform (FT) and grating spectroscopy over the wavelength range 900 A to 5.5 {mu}m. The spectra were observed in high-current continuous and pulsed hollow cathode discharges using FT spectrometers at the Kitt Peak National Observatory, Tucson, AZ and Imperial College, London and with the 10.7 m Normal Incidence Spectrograph at the National Institute of Standards and Technology. Roughly 12,900 lines were classified using 1027 energy levels of Fe II that were optimized to measured wavenumbers. The wavenumber uncertainties of lines in the FT spectra range from 10{sup -4} cm{sup -1} for strong lines around 4 {mu}m to 0.05 cm{sup -1} for weaker lines around 1500 A. The wavelength uncertainty of lines in the grating spectra is 0.005 A. The ionization energy of (130,655.4 {+-} 0.4) cm{sup -1} was estimated from the 3d{sup 6}({sup 5}D)5g and 3d{sup 6}({sup 5}D)6h levels.

  7. Synthesis, spectroscopic characterization, thermal analysis and electrical conductivity studies of Mg(II), Ca(II), Sr(II) and Ba(II) vitamin B2 complexes

    NASA Astrophysics Data System (ADS)

    Refat, Moamen S.; Moussa, Mohamed A. A.; Mohamed, Soha F.

    2011-05-01

    Riboflavin (RF) complexes of Mg(II), Ca(II), Sr(II) and Ba(II) were successfully synthesized. Structures of metal complexes obtained were confirmed and characterized by elemental analysis, molar conductance, and infrared spectra. DC electrical conductivity measurements indicated that the alkaline earth metal (II) complexes of RF ligand are non-electrolytes. Elemental analysis of chelates suggest that the metal(II) ligand ratio is 1:2 with structure formula as [M(RF) 2( X) 2]· nH 2O. Infrared assignments clearly show that RF ligand coordinated as a bidentate feature through azomethine nitrogen of pyrazine ring and C dbnd O of pyrimidine-2,4-dione. Thermal analyses of Mg(II), Ca(II), Sr(II) and Ba(II) complexes were investigated using (TG/DSC) under atmospheric nitrogen between 30 and 800 °C. The surface morphology of the complexes was studied by SEM. The electrical conductivities of RF and its metal complexes were also measured with DC electrical conductivity in the temperature range from room to 483 K.

  8. Use of anodic stripping voltammetry to determine zinc(II), lead(II), and copper(II) in foods

    SciTech Connect

    Maksimkina, L.M.; Gus'kova, V.P.

    1988-01-20

    The existing standard procedure for the polarographic determination of Zn, Pb, and Cu, based on the cathodic polarization of a dropping mercury electrode, is laborious and time-consuming and allows one to determine the above-mentioned trace elements only when they are separated beforehand. We consider the possibility of using anodic stripping voltammetry with a mercury film electrode for the simultaneous determination of Zn(II), Pb(II), and Cu(II) in foods.

  9. Quiet High Speed Fan II (QHSF II): Final Report

    NASA Technical Reports Server (NTRS)

    Kontos, Karen; Weir, Don; Ross, Dave

    2012-01-01

    This report details the aerodynamic, mechanical, structural design and fabrication of a Honey Engines Quiet High Speed Fan II (lower hub/tip ratio and higher specific flow than the Baseline I fan). This fan/nacelle system incorporates features such as advanced forward sweep and an advanced integrated fan/fan exit guide vane design that provides for the following characteristics: (1) Reduced noise at supersonic tip speeds, in comparison to current state-of-the-art fan technology; (2) Improved aeroelastic stability within the anticipated operating envelope; and (3) Aerodynamic performance consistent with current state-of-the-art fan technology. This fan was fabricated by Honeywell and tested in the NASA Glenn 9- by 15-Ft Low Speed Wind Tunnel for aerodynamic, aeromechanical, and acoustic performance.

  10. EDTA functionalized silica for removal of Cu(II), Zn(II) and Ni(II) from aqueous solution.

    PubMed

    Kumar, R; Barakat, M A; Daza, Y A; Woodcock, H L; Kuhn, J N

    2013-10-15

    Ethylenediaminetetraacetic acid (EDTA) functionalized silica adsorbent has been synthesized using (3-aminopropyl) triethoxylsilane (APTES) as a bridging link between silanol groups (SiOH) of silica and carboxylic group of EDTA. Fourier transform infrared spectroscopy (FTIR) and Temperature-programmed oxidation (TPO) analysis confirmed the grafting of EDTA onto the silica. The synthesized EDTA-silica was investigated as an adsorbent for removal of Cu(II), Zn(II) and Ni(II) from aqueous solution. The effect of solution pH, initial solution concentration, and contact time were studied. The removal of metal ions increased with the increase in solution pH, contact time and concentration. The maximum equilibrium time was found to be 45min for all three metal ions. Kinetics studies revealed that the adsorption of Cu(II), Zn(II) and Ni(II) onto EDTA-silica followed the pseudo-second order kinetics and film diffusion and intra-particle diffusion mechanism were involved. Adsorption equilibrium data were well fitted to Langmuir isotherm model and maximum monolayer adsorption capacity for Cu(II), Zn(II) and Ni(II) was 79.36, 74.07 and 67.56mg g(-1), respectively. Thermodynamic results reveal that the removal of metals onto EDTA-silica was endothermic and spontaneous in nature.

  11. Solid phase extraction of Cu(II), Ni(II), Pb(II), Cd(II) and Mn(II) ions with 1-(2-thiazolylazo)-2-naphthol loaded Amberlite XAD-1180.

    PubMed

    Tokalioğlu, Serife; Yilmaz, Vedat; Kartal, Senol

    2009-05-01

    A new method for separation and preconcentration of trace amounts of Cu(II), Ni(II), Pb(II), Cd(II) and Mn(II) ions in various matrices was proposed. The method is based on the adsorption and chelation of the metal ions on a column containing Amberlite XAD-1180 resin impregnated with 1-(2-thiazolylazo)-2-naphthol (TAN) reagent prior to their determination by flame atomic absorption spectrometry (FAAS). The effect of pH, type, concentration and volume of eluent, sample volume, flow rates of sample and elution solutions, and interfering ions have been investigated. The optimum pH for simultaneous retention of all the metal ions was 9. Eluent for quantitative elution was 20 ml of 2 mol l(-1) HNO(3). The optimum sample and eluent flow rates were found as 4 ml min(-1), and also sample volume was 500 ml, except for Mn (87% recovery). The sorption capacity of the resin was found to be 0.77, 0.41, 0.57, and 0.30 mg g(-1) for Cu(II), Ni(II), Cd(II), and Mn(II), respectively. The preconcentration factor of the method was 200 for Cu(II), 150 for Pb(II), 100 for Cd(II) and Ni(II), and 50 for Mn(II). The recovery values for all of the metal ions were > or = 95% and relative standard deviations (RSDs) were < or = 5.1%. The detection limit values were in the range of 0.03 and 1.19 microg l(-1). The accuracy of the method was confirmed by analysing the certified reference materials (TMDA 54.4 fortified lake water and GBW 07605 tea samples) and the recovery studies. This procedure was applied to the determination of Cu(II), Ni(II), Pb(II), Cd(II) and Mn(II) in waste water and lake water samples.

  12. Double quantum coherence electron spin resonance on coupled Cu(II)-Cu(II) electron spins

    NASA Astrophysics Data System (ADS)

    Becker, James S.; Saxena, Sunil

    2005-10-01

    We demonstrate for the first time the ability to generate double quantum coherences (DQCs) for the case of Cu(II). We show that small splittings (˜7 MHz) from the Cu(II)-Cu(II) electron-electron magnetic dipolar interaction can be reliably resolved even though the inhomogeneously broadened Cu(II) linewidth is ˜2 GHz. A Cu(II)-Cu(II) distance of 2.0 nm was measured on a model peptide system, thus, demonstrating that distances on the nanometer scale may be measured using DQC electron spin resonance (ESR).

  13. Start II, red ink, and Boris Yeltsin

    SciTech Connect

    Arbatov, A.

    1993-04-01

    Apart from the vulnerability implied by the START II treaty, it will bear the burden of the general political opposition to the Yeltsin administration. START II will be seen as part of an overall Yeltsin-Andrei Kozyrev foreign policy that is under fire for selling out Russian national interests in Yugoslavia, the Persian Gulf, and elsewhere. This article discusses public opinion concerning START II, the cost of its implementation, and the general purpose of the treaty.

  14. Sample Exchange Evaluation (SEE) Report - Phase II

    SciTech Connect

    Winters, W.I.

    1994-09-28

    This report describes the results from Phase II of the Sample Exchange Evaluation (SEE) Program, a joint effort to compare analytical laboratory performance on samples from the Hanford Site`s high-level waste tanks. In Phase II, the program has been expanded to include inorganic constituents in addition to radionuclides. Results from Phase II that exceeded 20% relative percent difference criteria are identified.

  15. [Study on hemolytic mechanism of polyphyllin II].

    PubMed

    Ning, Li-hua; Zhou, Bo; Zhang, Yao-xiang; Li, Xin-ping

    2015-09-01

    To study the hemolytic effect of polyphyllin II (PP II) mediated by anion channel protein and glucose transporter 1 (GLUT1), in order to initially reveal its hemolytic mechanism in vitro. In the experiment, the spectrophotometric method was adopted to detect the hemolysis of PP II in vitro and the effect of anion channel-related solution and blocker, glucose channel-related inhibitor and multi-target drugs dehydroepiandrosterone (DHEA) and diazepam on the hemolysis of PP II. The scanning electron microscope and transmission electron microscope were used to observe the effect of PP II on erythrocyte (RBC) morphology. The results showed that PP II -processed blood cells were severely deformed into spherocytes, acanthocyturia and vesicae. According to the results of the PP II hemolysis experiment in vitro, the anion hypertonic solution LiCl, NaHCO3, Na2SO4 and PBS significantly inhibited the hemolysis induced by PP II (P < 0.05), while blockers NPPB and DIDS remarkably promoted it (P < 0.01). Hyperosmotic sodium chloride, fructose and glucose at specific concentrations notably antagonized the hemolysis induced by PP II (P < 0.05). The glucose channel inhibitor Cytochalasin B and verapamil remarkably antagonized the hemolysis induced by PP II (P < 0.01). The hemolysis induced by PP II could also be antagonized by 1 gmol x L(1) diazepam and 100 μmol x L(-1) DHEA pretreated for 1 min (P < 0.01). In conclusion, the hemolytic mechanism of PP II in vitro may be related to the increase in intracellular osmotic pressure and rupture of erythrocytes by changing the anion channel transport activity, with GLUT1 as the major competitive interaction site. PMID:26983211

  16. AGEX II: Technical quarterly, Volume 2

    SciTech Connect

    Ekdahl, C.

    1995-03-01

    The AGEX II Technical Quarterly publishes short technical contributions on above ground experiments that use pulsed power and laser drivers. The Quarterly is intended to provide rapid exposure of timely technical ideas and results as well as a means for documenting AGEX II progress and scientific quality for the AGEX II community. Suitable topics include experimental results, diagnostic apparatus, theoretical design, and scaling, among others.

  17. Telemetry Tests Of The Advanced Receiver II

    NASA Technical Reports Server (NTRS)

    Hinedi, Sami M.; Bevan, Roland P.; Marina, Miguel

    1993-01-01

    Report describes telemetry tests of Advanced Receiver II (ARX-II): digital radio receiving subsystem operating on intermediate-frequency output of another receiving subsystem called "multimission receiver" (MMR), detecting carrier, subcarrier, and data-symbol signals transmitted by spacecraft, and extracts Doppler information from signals. Analysis of data shows performance of MMR/ARX-II system comparable and sometimes superior to performances of Blk-III/BPA and Blk-III/SDA/SSA systems.

  18. ExodusII Finite Element Data Model

    SciTech Connect

    2005-05-14

    EXODUS II is a model developed to store and retrieve data for finite element analyses. It is used for preprocessing (problem definition), postprocessing (results visualization), as well as code to code data transfer. An EXODUS II data file is a random access, machine independent, binary file that is written and read via C, C++, or Fortran library routines which comprise the Application Programming Interface. (exodus II is based on netcdf)

  19. SAGE II aerosol correlative observations - Profile measurements

    NASA Technical Reports Server (NTRS)

    Osborn, M. T.; Rosen, J. M.; Mccormick, M. P.; Wang, Pi-Huan; Livinfston, J. M.

    1989-01-01

    Profiles of the aerosol extinction measurements from the Stratospheric Aerosol and Gas Experiment (SAGE) II are compared with profiles from five correlative experiments between November 1984 and July 1986. The correlative profiles were derived from six-channel dustsonde measurements and two-wavelength lidar backscatter data. The correlation between the dustsonde- and lidar-derived measurements and the SAGE II data is good, validating the SAGE II lower stratospheric aerosol extinction measurements.

  20. Probing outflows in z = 1 ∼ 2 galaxies through Fe II/Fe II* multiplets

    SciTech Connect

    Tang, Yuping; Giavalisco, Mauro; Guo, Yicheng

    2014-10-01

    We report on a study of the 2300-2600 Å Fe II/Fe II* multiplets in the rest-UV spectra of star-forming galaxies at 1.0 < z < 2.6 as probes of galactic-scale outflows. We extracted a mass-limited sample of 97 galaxies at z ∼ 1.0-2.6 from ultra-deep spectra obtained during the GMASS spectroscopic survey in the GOODS South field with the Very Large Telescope and FORS2. We obtain robust measures of the rest equivalent width of the Fe II absorption lines down to a limit of W{sub r} > 1.5 Å and of the Fe II* emission lines to W{sub r} > 0.5 Å. Whenever we can measure the systemic redshift of the galaxies from the [O II] emission line, we find that both the Fe II and Mg II absorption lines are blueshifted, indicating that both species trace gaseous outflows. We also find, however, that the Fe II gas has generally lower outflow velocity relative to that of Mg II. We investigate the variation of Fe II line profiles as a function of the radiative transfer properties of the lines, and find that transitions with higher oscillator strengths are more blueshifted in terms of both line centroids and line wings. We discuss the possibility that Fe II lines are suppressed by stellar absorptions. The lower velocities of the Fe II lines relative to the Mg II doublet, as well as the absence of spatially extended Fe II* emission in two-dimensional stacked spectra, suggest that most clouds responsible for Fe II absorption lie close (3 ∼ 4 kpc) to the disks of galaxies. We show that the Fe II/Fe II* multiplets offer unique probes of the kinematic structure of galactic outflows.

  1. Neurosurgical notes: World War II.

    PubMed

    Pool, J L

    2000-03-01

    This concerns my activities as a neurosurgeon in the European Theater of Operations and the North African, Tunisian campaign, during World War II. Action during the Battle of the Bulge came later. Our mobile tent hospital, the 9th Evacuation Hospital, was similar to that depicted in the television show M*A*S*H. To lend flavor to these comments, I have referred to medical and surgical matters in other units as well as our own, mentioned global aspects of the war, and included vignettes of life off-duty. The story begins after induction into the Army Medical Corps as a volunteer in July 1942 and ends with honorable discharge in April 1946. PMID:10719869

  2. EPACT II: project and methods.

    PubMed

    Juillerat, Pascal; Froehlich, Florian; Felley, Christian; Pittet, Valérie; Mottet, Christian; Gonvers, Jean-Jacques; Michetti, Pierre; Vader, John-Paul

    2007-01-01

    Building on the first European Panel on the Appropriateness of Crohn's Disease Treatment (EPACT I) which was held in Lausanne at the beginning of March 2004, a new panel will be convened in Switzerland (EPACT II, November to December 2007) to update this work. A combined evidence- and panel-based method (RAND) will be applied to assess the appropriateness of therapy for Crohn's disease (CD). In preparation for the meeting of experts, reviews of evidence-based literature were prepared for major clinical presentations of CD. During the meeting, an international multidis- ciplinary panel that includes gastroenterologists, surgeons and general practitioners weigh the strength of evidence and apply their clinical experience when assessing the appropriateness of therapy for 569 specific indications (clinical scenarios). This chapter describes in detail the process of updating the literature review and the systematic approach of the RAND Appropriateness Method used during the expert panel meeting. PMID:18239398

  3. Type II Transmembrane Serine Proteases*

    PubMed Central

    Bugge, Thomas H.; Antalis, Toni M.; Wu, Qingyu

    2009-01-01

    Analysis of genome and expressed sequence tag data bases at the turn of the millennium unveiled a new protease family named the type II transmembrane serine proteases (TTSPs) in a Journal of Biological Chemistry minireview (Hooper, J. D., Clements, J. A., Quigley, J. P., and Antalis, T. M. (2001) J. Biol. Chem. 276, 857–860). Since then, the number of known TTSPs has more than doubled, and more importantly, our understanding of the physiological functions of individual TTSPs and their contribution to human disease has greatly increased. Progress has also been made in identifying molecular substrates and endogenous inhibitors. This minireview summarizes the current knowledge of the rapidly advancing TTSP field. PMID:19487698

  4. Optimization of simultaneous electrochemical determination of Cd(II), Pb(II), Cu(II) and Hg(II) at carbon nanotube-modified graphite electrodes.

    PubMed

    Pikna, L'ubomír; Heželová, Mária; Kováčová, Zuzana

    2015-01-01

    The health of the environment is worsening every day. Monitoring of potentially toxic elements and remediation of environmental pollution are necessary. Therefore, the research and development of simple, inexpensive, portable and effective sensors is important. Electrochemistry is a useful component of the field of environment monitoring. The present study focuses on evaluating and comparing three types of electrodes (PIGE, PIGE/MWCNT/HNO3 and PIGE/MWCNT/EDTA/HNO3) employed for the simultaneous electrochemical determination of four potentially toxic elements: Cd(II), Pb(II), Cu(II) and Hg(II). Cyclic voltammograms were measured in an acetate buffer. The LOD, LOQ, the standard and relative precisions of the method and a prediction intervals were calculated (according to the technical procedure DIN 32 645) for the three electrodes and for each measured element. The LOD for PIGE/CNT/HNO3 (the electrode with narrowest calculated prediction intervals) was 2.98 × 10(-7) mol L(-1) for Cd(II), 4.83 × 10(-7) mol L(-1) for Pb(II), 3.81 × 10(-7) mol L(-1) for Cu(II), 6.79 × 10(-7) mol L(-1) for Hg(II). One of the benefits of this study was the determination of the amount of Hg(II) in the mixture of other elements.

  5. SWAMI II technology transfer plan

    SciTech Connect

    Ward, C.R.; Peterson, K.D.; Harpring, L.J.; Immel, D.M.; Jones, J.D.; Mallet, W.R.

    1995-12-31

    Thousands of drums of radioactive/hazardous/mixed waste are currently stored at DOE sites throughout US; they are stored in warehouse facilities on an interim basis, pending final disposition. Recent emphasis on anticipated decommissioning of facilities indicates that many more drums of waste will be generated, requiring additional storage. Federal and state regulations dictate that hazardous waste covered by RCRA be inspected periodically for container degradation and to verify inventories. All known DOE waste storage facilities are currently inspected manually. A system to perform robotic inspection of waste drums is under development by the SRTC Robotics Group of WSRC; it is called the Stored Waste Autonomous Mobile Inspector (SWAMI). The first version, SWAMI I, was developed by the Savannah River Technology Center (SRTC) as a proof of principle system for autonomous inspection of drums in a warehouse. SWAMI I was based on the Transitions Research Corporation (TRC) HelpMate mobile robot. TRC modified the Helpmate to navigate in aisles of drums. SRTC added subsystems to SWAMI I to determine its position in open areas, read bar code labels on the drums up to three levels high, capture images of the drums and perform a radiation survey of the floor in the aisles. The radiation survey was based on SRTC patented technology first implemented on the Semi-Intelligent Mobile Observing Navigator (SIMON). The radiation survey is not essential for the inspection of drums, but is an option that can increase the utility and effectiveness of SWAMI in warehouses with radioactive and/or mixed waste. All the sensors on SWAMI I were fixed on the vehicle. From the success of SWAMI I, a second version, SWAMI II, was developed; it will be evaluated at Fernald and tested with two other mobile robots. Intent is to transfer the technology developed for SWAMI I and II to industry so that it can supply additional units for purchase for drum inspection.

  6. Phase II metabolism of benzene.

    PubMed Central

    Schrenk, D; Orzechowski, A; Schwarz, L R; Snyder, R; Burchell, B; Ingelman-Sundberg, M; Bock, K W

    1996-01-01

    The hepatic metabolism of benzene is thought to be a prerequisite for its bony marrow toxicity. However, the complete pattern of benzene metabolites formed in the liver and their role in bone marrow toxicity are not fully understood. Therefore, benzene metabolism was studied in isolated rodent hepatocytes. Rat hepatocytes released benzene-1,2-dihydrodiol, hydroquinone (HQ), catechol (CT), phenol (PH), trans-trans-muconic acid, and a number of phase II metabolites such as PH sulfate and PH glucuronide. Pretreatment of animals with 3-methylcholantrene (3-MC) markedly increased PH glucuronide formation while PH sulfate formation was decreased. Likewise, V79 cells transfected with the 3-MC-inducible rat UGT1.6 cDNA showed a considerable rate of PH and HQ glucuronidation. In addition to inducing glucuronidation of phenols, 3-MC treatment (reported to protect rats from the myelotoxicity of benzene) resulted in a decrease of hepatic CYP2E1. In contrast, pretreatment of rats with the CYP2E1-inducer isopropanol strongly enhanced benzene metabolism and the formation of phenolic metabolites. Mouse hepatocytes formed much higher amounts of HQ than rat hepatocytes and considerable amounts of 1,2,4-trihydroxybenzene (THB) sulfate and HQ sulfate. In conclusion, the protective effect of 3-MC in rats is probably due to a shift from the labile PH sulfate to the more stable PH glucuronide, and to a decrease in hepatic CYP2E1. The higher susceptibility of mice toward benzene may be related to the high rate of formation of the myelotoxic metabolite HQ and the semistable phase II metabolites HQ sulfate and THB sulfate. Images Figure 4. PMID:9118891

  7. Accurate Ritz Wavelengths of Parity-forbidden [Co II] and [V II] Lines of Astrophysical Interest

    NASA Astrophysics Data System (ADS)

    Ruffoni, M. P.; Pickering, J. C.

    2013-08-01

    We report a comprehensive list of accurate Ritz wavelengths for parity-forbidden [Co II] and [V II] lines obtained from the analysis of energy levels measured in the laboratory with Fourier transform emission spectroscopy. Such lines, particularly those in the infrared, are in demand for the analysis of low-density astrophysical plasmas in and around objects such as planetary nebulae, star-forming regions, and active galactic nuclei. Transitions between all known metastable levels of Co II and V II are included in our analysis, producing wavelengths for 1477 [V II] lines and 782 [Co II] lines. Of these, 170 [V II] lines and 171 [Co II] lines arise from transitions with calculated transition probabilities greater than 1 × 10-2 s-1 and upper level excitations of less than 5 eV, and thus are likely to be observed in astrophysical spectra.

  8. ACCURATE RITZ WAVELENGTHS OF PARITY-FORBIDDEN [Co II] AND [V II] LINES OF ASTROPHYSICAL INTEREST

    SciTech Connect

    Ruffoni, M. P.; Pickering, J. C.

    2013-08-15

    We report a comprehensive list of accurate Ritz wavelengths for parity-forbidden [Co II] and [V II] lines obtained from the analysis of energy levels measured in the laboratory with Fourier transform emission spectroscopy. Such lines, particularly those in the infrared, are in demand for the analysis of low-density astrophysical plasmas in and around objects such as planetary nebulae, star-forming regions, and active galactic nuclei. Transitions between all known metastable levels of Co II and V II are included in our analysis, producing wavelengths for 1477 [V II] lines and 782 [Co II] lines. Of these, 170 [V II] lines and 171 [Co II] lines arise from transitions with calculated transition probabilities greater than 1 Multiplication-Sign 10{sup -2} s{sup -1} and upper level excitations of less than 5 eV, and thus are likely to be observed in astrophysical spectra.

  9. Kinetics of Formation of Cobalt(II)- and Nickel(II) Carbonic Anhydrase.

    ERIC Educational Resources Information Center

    McQuate, Robert S.; Reardon, John E.

    1978-01-01

    Discusses the kinetic behavior associated with the interaction of metal ions with apocarbonic anhydrase, focusing on the formation of two metallocarbonic anhydrase--the biochemically active Co(II) and the inactive Ni(II)derivatives. (GA)

  10. Molecular cloning, sequencing, and expression analysis of cDNA encoding metalloprotein II (MP II) induced by single and combined metals (Cu(II), Cd(II)) in polychaeta Perinereis aibuhitensis.

    PubMed

    Yang, Dazuo; Zhou, Yibing; Zhao, Huan; Zhou, Xiaoxiao; Sun, Na; Wang, Bin; Yuan, Xiutang

    2012-11-01

    We amplified and analyzed the complete cDNA of metalloprotein II (MP II) from the somatic muscle of the polychaete Perinereis aibuhitensis, the full length cDNA is 904 bp encoding 119 amino acids. The MP II cDNA sequence was subjected to BLAST searching in NCBI and was found to share high homology with hemerythrin of other worms. MP II expression of P. aibuhitensis exposed to single and combined metals (Cu(II), Cd(II)) was analyzed using real time-PCR. MP II mRNA expression increased at the start of Cu(II) exposure, then decreased and finally return to the normal level. Expression pattern of MP II under Cd(II) exposure was time- and dose-dependent. MP II expression induced by a combination of Cd(II) and Cu(II) was similar to that induced by Cd(II) alone.

  11. Competitive adsorption of copper(II), cadmium(II), lead(II) and zinc(II) onto basic oxygen furnace slag.

    PubMed

    Xue, Yongjie; Hou, Haobo; Zhu, Shujing

    2009-02-15

    Polluted and contaminated water can often contain more than one heavy metal species. It is possible that the behavior of a particular metal species in a solution system will be affected by the presence of other metals. In this study, we have investigated the adsorption of Cd(II), Cu(II), Pb(II), and Zn(II) onto basic oxygen furnace slag (BOF slag) in single- and multi-element solution systems as a function of pH and concentration, in a background solution of 0.01M NaNO(3). In adsorption edge experiments, the pH was varied from 2.0 to 13.0 with total metal concentration 0.84mM in the single element system and 0.21mM each of Cd(II), Cu(II), Pb(II), and Zn(II) in the multi-element system. The value of pH(50) (the pH at which 50% adsorption occurs) was found to follow the sequence Zn>Cu>Pb>Cd in single-element systems, but Pb>Cu>Zn>Cd in the multi-element system. Adsorption isotherms at pH 6.0 in the multi-element systems showed that there is competition among various metals for adsorption sites on BOF slag. The adsorption and potentiometric titrations data for various slag-metal systems were modeled using an extended constant-capacitance surface complexation model that assumed an ion-exchange process below pH 6.5 and the formation of inner-sphere surface complexes at higher pH. Inner-sphere complexation was more dominant for the Cu(II), Pb(II) and Zn(II) systems.

  12. Cohesin regulates MHC class II genes through interactions with MHC class II insulators.

    PubMed

    Majumder, Parimal; Boss, Jeremy M

    2011-10-15

    Cohesin is a multiprotein, ringed complex that is most well-known for its role in stabilizing the association of sister chromatids between S phase and M. More recently, cohesin was found to be associated with transcriptional insulators, elements that are associated with the organization of chromatin into regulatory domains. The human MHC class II (MHC-II) locus contains 10 intergenic elements, termed MHC-II insulators, which bind the transcriptional insulator protein CCCTC-binding factor. MHC-II insulators interact with each other, forming a base architecture of discrete loops and potential regulatory domains. When MHC-II genes are expressed, their proximal promoter regulatory regions reorganize to the foci established by the interacting MHC-II insulators. MHC-II insulators also bind cohesin, but the functional role of cohesin in regulating this system is not known. In this article, we show that the binding of cohesin to MHC-II insulators occurred irrespective of MHC-II expression but was required for optimal expression of the HLA-DR and HLA-DQ genes. In a DNA-dependent manner, cohesin subunits interacted with CCCTC-binding factor and the MHC-II-specific transcription factors regulatory factor X and CIITA. Intriguingly, cohesin subunits were important for DNA looping interactions between the HLA-DRA promoter region and a 5' MHC-II insulator but were not required for interactions between the MHC-II insulators themselves. This latter observation introduces cohesin as a regulator of MHC-II expression by initiating or stabilizing MHC-II promoter regulatory element interactions with the MHC-II insulator elements, events that are required for maximal MHC-II transcription.

  13. Competitive Fe(II)-Zn(II) uptake on a synthetic montmorillonite.

    PubMed

    Soltermann, Daniela; Marques Fernandes, Maria; Baeyens, Bart; Miehé-Brendlé, Jocelyne; Dähn, Rainer

    2014-01-01

    The interaction of Fe(II) with clay minerals is of particular relevance in global geochemical processes controlling metal and nutrient cycles and the fate of contaminants. In this context, the influence of competitive sorption effects between Fe(II) and other relevant transition metals on their uptake characteristics and mobility remains an important issue. Macroscopic sorption experiments combined with surface complexation modeling and extended X-ray absorption fine structure (EXAFS) spectroscopy were applied to elucidate competitive sorption processes between divalent Fe and Zn at the clay mineral-water interface. Sorption isotherms were measured on a synthetic iron-free montmorillonite (IFM) under anoxic conditions (O2 <0.1 ppm) for the combinations of Zn(II)/Fe(II) and Fe(II)/Zn(II), where the former metal in each pair represents the trace metal (<10(-7) M) and the latter the competing metal at higher concentrations (10(-7) to 10(-3) M). Results of the batch sorption and EXAFS measurements indicated that Fe(II) is competing with trace Zn(II) for the same type of strong sites if Fe(II) is present in excess, whereas no competition between trace Fe(II) and Zn(II) was observed if Zn(II) is present at high concentrations. The noncompetitive behavior suggests the existence of sorption sites which have a higher affinity for Fe(III), where surface-induced oxidation of the sorbed Fe(II) to Fe(III) occurred, and which are not accessible for Zn(II). The understanding of this competitive uptake mechanism between Fe(II) and Zn(II) is of great importance to assess the bioavailability and mobility of transition metals in the natural environment. PMID:24289476

  14. Apache Leap Tuff INTRAVAL experiments - results and lessons learned

    SciTech Connect

    Rasmussen, T.C.; Rhodes, S.C.; Guzman, A.; Neuman, S.P.

    1996-03-01

    Data from laboratory and field experiments in unsaturated fractured rock are summarized and interpreted for the purpose of evaluating conceptual and numerical models of fluid, heat and solute transport. The experiments were conducted at four scales, in small cores (2.5-cm long by 6-cm across), a large core (12-cm long by 10-cm across), a small block containing a single fracture (20 x 21 x 93 cm), and at field scales in boreholes (30-m long by 10-cm across) at three scales (1/2-, 1- and 3-meters). The smallest scale in the laboratory provided isothermal hydraulic and thermal properties of unfractured rock. Nonisothermal heat, fluid and solute transport experiments were conducted using the large core. Isothermal gas and liquid flow experiments were conducted in the fractured block. Field-scale experiments using air were used to obtain in situ permeability estimates as a function of the measurement scale. Interpretation of experimental results provides guidance for resolving uncertainties related to radionuclide migration from high level waste repositories in unsaturated fractured rock.

  15. Apaches in Three Dimensions: Anthropology, History and Literature.

    ERIC Educational Resources Information Center

    Oliva, Leo E.

    As many disciplines as possible should be used in the teaching of Indian Studies. In particular, creative literature adds another dimension to the understanding of Indian culture and the history of Indian-white relations when it is used in conjunction with historical and anthropological material. The serious student should read historical novels…

  16. MaNGA: Mapping Nearby Galaxies at Apache Point Observatory

    NASA Astrophysics Data System (ADS)

    Weijmans, A.-M.; MaNGA Team

    2016-10-01

    MaNGA (Mapping Nearby Galaxies at APO) is a galaxy integral-field spectroscopic survey within the fourth generation Sloan Digital Sky Survey (SDSS-IV). It will be mapping the composition and kinematics of gas and stars in 10,000 nearby galaxies, using 17 differently sized fiber bundles. MaNGA's goal is to provide new insights in galaxy formation and evolution, and to deliver a local benchmark for current and future high-redshift studies.

  17. White Mountain Apache Tribe Water Rights Quantification Act of 2010

    THOMAS, 111th Congress

    Rep. Kirkpatrick, Ann [D-AZ-1

    2009-02-13

    03/26/2010 Read twice. Placed on Senate Legislative Calendar under General Orders. Calendar No. 340. (All Actions) Notes: For further action, see H.R.4783, which became Public Law 111-291 on 12/8/2010. Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  18. White Mountain Apache Tribe Water Rights Quantification Act of 2009

    THOMAS, 111th Congress

    Sen. Kyl, Jon [R-AZ

    2009-01-26

    01/21/2010 Placed on Senate Legislative Calendar under General Orders. Calendar No. 260. (All Actions) Notes: For further action, see H.R.4783, which became Public Law 111-291 on 12/8/2010. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  19. A N-heterocyclic tetracarbene Pd(ii) moiety containing a Pd(ii)-Pb(ii) bimetallic MOF for three-component cyclotrimerization via benzyne.

    PubMed

    Dong, Ying; Li, Yue; Wei, Yong-Liang; Wang, Jian-Cheng; Ma, Jian-Ping; Ji, Jun; Yao, Bing-Jian; Dong, Yu-Bin

    2016-08-18

    A novel Pd(ii)-Pb(ii) bimetallic metal-organic framework Pd(ii)-Pb(ii)-MOF (B) which contains an N-heterocyclic tetracarbene Pd(ii) moiety was synthesized based on a chelating N-heterocyclic dicarbene Pd(ii)-NHDC ligand (A) under solvothermal conditions. It can be a highly active heterogeneous catalyst for three-component cyclotrimerization via benzyne species.

  20. Preschool Racial Attitude Measure II (PRAM II): Technical Report #1: 1970-71 Standardization Study.

    ERIC Educational Resources Information Center

    Williams, John E.

    This report provides detailed technical information concerning the Preschool Racial Attitude Measure II (PRAM II) a method for assessing the attitudes of pre-literate children toward light- and dark-skinned individuals. Several major changes were involved in the PRAM II revision: (1) the length was doubled, (2) the general artistic quality of the…

  1. 40 CFR Table II-2 to Subpart II - Collection Efficiencies of Anaerobic Processes

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Collection Efficiencies of Anaerobic Processes II Table II-2 to Subpart II Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Industrial Wastewater Treatment Pt....

  2. 40 CFR Table II-2 to Subpart II - Collection Efficiencies of Anaerobic Processes

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Collection Efficiencies of Anaerobic Processes II Table II-2 to Subpart II Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Industrial Wastewater Treatment Pt....

  3. Diet History Questionnaire II & Canadian Diet History Questionnaire II: Web-based DHQ

    Cancer.gov

    The Web-based versions of DHQ II and C-DHQ II are identical in content to the paper forms. By automating the DHQ II and providing versions on the Web for public use, researchers have another tool to collect and analyze food frequency questionnaire data.

  4. FOREWORD: HELAS II International Conference

    NASA Astrophysics Data System (ADS)

    Gizon, Laurent; Roth, Markus

    2008-07-01

    Volume 118 (2008) of Journal of Physics: Conference Series provides a written record of the talks and posters presented at the HELAS II International Conference `Helioseismology, Asteroseismology and MHD Connections'. The conference was held during the week 20-24 August 2007 in Göttingen, Germany, jointly hosted by the Max Planck Institute for Solar System Research and the Faculty of Physics of the University of Göttingen. A total of 140 scientists from all over the world attended. The Scientific Organizing Committee consisted of Conny Aerts, Annie Baglin, Jørgen Christensen-Dalsgaard, Thierry Corbard, Jadwiga Daszyńska-Daszkiewicz, Stefan Dreizler, Yvonne Elsworth, Laurent Gizon (Chairman), Wolfgang Glatzel, Frank Hill, Donald Kurtz, Oskar von der Lühe, Maria Pia Di Mauro, Mário Monteiro, Pere Pallé, Markus Roth, Philip Scherrer, Manfred Schüssler, and Michael Thompson. HELAS stands for the European Helio- and Asteroseismology Network, a Coordination Action supported by the sixth Framework Programme of the European Union. It aims to bring together researchers in the fields of solar and stellar oscillations. This volume consists of 91 articles organized into sections that reflect the scientific programme of the conference: 012001-07 Wave diagnostics in physics, geophysics and astrophysics 012008-09 Perspectives on helio- and asteroseismology 012010-17 Asteroseismology: Observations 012018-25 Asteroseismology: Theory 012026-32 Global helioseismology and solar models 012033-38 Local helioseismology and magnetic activity 012039-44 Future observational projects in helio- and asteroseismology 012045-91 Poster papers. The overwhelming majority of papers discuss the seismology of the Sun and stars. Papers in the first section provide a broader perspective on wave phenomena and techniques for probing other physical systems, from living beings to the universe as a whole. We were extremely fortunate to have particularly distinguished experts to cover these topics

  5. Adsorption of Cd(II), Cu(II) and Ni(II) ions by cross-linking chitosan/rectorite nano-hybrid composite microspheres.

    PubMed

    Zeng, Lixuan; Chen, Yufei; Zhang, Qiuyun; Guo, Xingmei; Peng, Yanni; Xiao, Huijuan; Chen, Xiaocheng; Luo, Jiwen

    2015-10-01

    Chitosan/rectorie (CTS/REC) nano-hybrid composite microsphere was prepared by changing the proportion of CTS/REC with 2:1, 3:1 and 4:1. Compared with the pure cross-linking chitosan microsphere, the nano-hybrid composite microsphere was proved to have better sorption capacity of Cd(II), Cu(II) and Ni(II), especially 2:1(CTS/REC-1). The adsorption behavior of the microsphere of Cd(II), Cu(II) and Ni(II) was investigated in single and binary metal systems. In single system, the equilibrium studies showed that the adsorption of Cd(II), Cu(II) and Ni(II) followed the Langmuir model and the pseudo-second-order kinetic model. The negative values of (ΔG) suggested that the adsorption process was spontaneous. In binary system, the combined action of the metals was found to be antagonistic and the metal sorption followed the order of Cu(II)>Cd(II)>Ni(II). The regeneration studies indicated that EDTA desorbed Cd(II), Cu(II) and Ni(II) from cross-linking microspheres better than HCl. The FT-IR and XPS spectra showed that coordination bonds were formed between Cd(II), Cu(II) and Ni(II) and the nitrogen atoms of cross-linking CTS/REC nano-hybrid composite microspheres. PMID:26076634

  6. Synthesis, DFT Calculation, and Antimicrobial Studies of Novel Zn(II), Co(II), Cu(II), and Mn(II) Heteroleptic Complexes Containing Benzoylacetone and Dithiocarbamate

    PubMed Central

    Ekennia, Anthony C.; Onwudiwe, Damian C.; Olasunkanmi, Lukman O.; Osowole, Aderoju A.; Ebenso, Eno E.

    2015-01-01

    Heteroleptic complexes of zinc(II), copper(II), manganese(II), and cobalt(II) of the types [MLL′(H2O)2]·nH2O and [MLL′]·nH2O have been synthesized using sodium N-methyl-N-phenyldithiocarbamate (L) and benzoylacetone (L′). The metal complexes were characterized by elemental analysis, electrical conductance, magnetic susceptibility, infrared (IR), and UV-visible spectroscopic studies. The electrical conductance measurements revealed the nonelectrolytic nature of the synthesized complexes. The results of the elemental analyses, magnetic susceptibility measurements, and electronic spectra inferred that the Zn(II) complex adopted a four-coordinate geometry while the Co(II), Cu(II), and Mn(II) complexes assumed octahedral geometries. The IR spectra showed that the metal ions coordinated with the ligands via the S- and O-donor atoms. The geometry, electronic, and thermodynamic parameters of the complexes were obtained from density functional theory (DFT) calculations. The spin density distributions, relative strength of H–bonds, and thermodynamic parameters revealed that the order of stability of the metal complexes is Mn < Co < Cu > Zn. The agar diffusion methods were used to study the antimicrobial activity of the complexes against two Gram positive bacteria (S. aureus and S. pneumoniae), one Gram negative bacterium (E. coli), and two fungi organisms (A. niger and A. candida) and the complexes showed a broad spectrum of activities against the microbes. PMID:26681931

  7. Arkansas HEA Title II. State Report, 2004

    ERIC Educational Resources Information Center

    Arkansas Department of Education, 2005

    2005-01-01

    In October 1998, Congress enacted Title II, Sections 207 and 208 (as amendments to the Higher Education Act) which support the efforts of States, Institutions of Higher Education, and their School District partners to improve the recruitment, preparation, and support of new teachers. The Title II report includes specifications, conditions and…

  8. Micro Channel/Multibus-II Interface Circuit

    NASA Technical Reports Server (NTRS)

    D'Ambrose, John J.; Jaworski, Richard C.; Heise, Nyles N.; Thornton, David N.

    1991-01-01

    Micro Channel/Multibus-II interface circuit provides electrical interconnections enabling communications between Micro Channels of IBM Personal System/2 computers and IEEE 1296 standard Multibus-II parallel system bus (iPSB). Made mostly of commercially available parts, interface enables independent Micro Channels to communicate over iPSB without modification.

  9. Run II data analysis on the grid

    SciTech Connect

    Igor Mandrichenko, Igor Terekhov and Frank Wurthwein

    2002-12-02

    In this document, we begin the technical design for the distributed RunII computing for CDF and D0. The present paper defines the three components of the data handling area of Run II computing, namely the Data Handling System, the Storage System and the Application. We outline their functionality and interaction between them. We identify necessary and desirable elements of the interfaces.

  10. The CDF SVX II detector upgrade

    SciTech Connect

    Skarha, J.E.

    1993-10-01

    The proposed CDF SVX II detector upgrade for secondary vertex detection during the Fermilab Tevatron Run II collider run is described. The general design and important features of this silicon vertex detector are presented. The CDF physics goals which are addressed by this detector are also given.

  11. World War II: A Technology Lesson Plan.

    ERIC Educational Resources Information Center

    Hagar, Suzy

    1990-01-01

    Presents a class activity on the history, causes, and consequences of World War II. Focuses on the development and deployment of the atomic bomb. Utilizes a Video Encyclopedia Program for historical background. Divides the class into groups that are responsible for researching and preparing a videotape on a World War II topic. (RW)

  12. Geology of the Phase II System

    SciTech Connect

    Laney, R.; Laughlin, A. William

    1980-11-19

    This is a report on the analysis of EE-2 cuttings and thin sections, geologic characterization of the Phase II system, comparison with Phase 1, and geologic speculations and recommendations concerning Phase II. The EE-2 litholog has been included in the pocket.

  13. Syntheses of Arnottin I and Arnottin II

    PubMed Central

    Moschitto, Matthew J.; Anthony, David R.; Lewis, Chad A.

    2015-01-01

    Short total syntheses of arnottin I and II were accomplished in 5 and 6 steps, respectively. A sesamol-benzyne cycloaddition with a 3-furyl-benzoate followed by regiospecific lactonization provided rapid, large-scale access to the core of arnottin I. Saponification of arnottin I and hypervalent iodide mediated spirocyclization provided an efficient and direct preparation of racemic arnottin II. PMID:25748275

  14. The CNET Automated Budget System (CABS) II.

    ERIC Educational Resources Information Center

    Middleton, Morris G.; And Others

    The Chief of Naval Education and Training (CNET) Automated Budget System II (CABS II) is an improved and expanded version of an earlier system which was developed by the Training Analysis and Evaluation Group (TAEG) to provide an efficient, easy means of handling the large volume of data necessary to produce budget documents. Intended as a guide…

  15. Biology II Curriculum Guide. Bulletin 1820.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge. Div. of Academic Programs.

    In 1986, the Louisiana State Board of Elementary and Secondary Education requested that an advanced course in Biology II be developed. The resulting curriculum guide contains grade appropriate goals, skills, and competencies; suggested activities; suggested materials of instruction; and minimum time allotments for instruction. Biology II is a…

  16. TRUPACT-II procedures and maintenance instructions

    SciTech Connect

    1994-01-14

    The purpose of this document is to provide the technical requirements for operation, inspection and maintenance of a TRUPACT-II Shipping Package and directly related components. This document shall supply the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP) and Certificate of Compliance (C of C) 9218. In the event there is a conflict between this document and the TRUPACT-II SARP (NRC Certificate of Compliance No. 9218), the TRUPACT-II SARP shall govern. This document details the operations, maintenance, repair, replacement of components, as well as the documentation required and the procedures to be followed to maintain the integrity of the TRUPACT-II container. These procedures may be modified for site use, but as a minimum all parameters and format listed herein must be included in any site modified version. For convenience and where applicable steps may be performed out of sequence. Packaging and payload handling equipment and transport trailers have been specifically designed for use with the TRUPACT-II Packaging. This document discusses the minimum required procedures for use of the adjustable center of gravity lift fixture and the TRUPACT-II transport trailer in conjunction with the TRUPACT-II Packaging.

  17. World War II Memorial Learning Activities.

    ERIC Educational Resources Information Center

    Tennessee State Dept. of Education, Nashville.

    These learning activities can help students get the most out of a visit to the Tennessee World War II Memorial, a group of ten pylons located in Nashville (Tennessee). Each pylon contains informational text about the events of World War II. The ten pylons are listed as: (1) "Pylon E-1--Terror: America Enters the War against Fascism, June 1940";…

  18. First Run II results from CDF

    SciTech Connect

    S. Donati

    2002-06-04

    In this paper we report on the first run II results from the CDF experiment. A brief description of the Tevatron collider and CDF detector upgrades and performance achieved in the first part of run II is followed by the CDF expectations in the fields of beauty, top, electroweak and Higgs physics.

  19. Hearing Restoration in Neurofibromatosis Type II Patients

    PubMed Central

    Lee, Jeon Mi; Chang, Jin Woo; Choi, Jae Young

    2016-01-01

    Patients with neurofibromatosis type II will eventually succumb to bilateral deafness. For patients with hearing loss, modern medical science technology can provide efficient hearing restoration through a number of various methods. In this article, several hearing restoration methods for patients with neurofibromatosis type II are introduced. PMID:27189272

  20. World War II Homefront: A Historiography.

    ERIC Educational Resources Information Center

    Winkler, Allan M.

    2002-01-01

    Highlights the scholarship that exists on the World War II homefront covering topics such as World War II as a good war, Franklin D. Roosevelt, economic policy, propaganda, status of women and women's employment, the role of African Americans, racial violence, and the Japanese American experience. (CMK)

  1. Synthesis, DFT Calculation, and Antimicrobial Studies of Novel Zn(II), Co(II), Cu(II), and Mn(II) Heteroleptic Complexes Containing Benzoylacetone and Dithiocarbamate.

    PubMed

    Ekennia, Anthony C; Onwudiwe, Damian C; Olasunkanmi, Lukman O; Osowole, Aderoju A; Ebenso, Eno E

    2015-01-01

    Heteroleptic complexes of zinc(II), copper(II), manganese(II), and cobalt(II) of the types [MLL'(H2O)2]·nH2O and [MLL']·nH2O have been synthesized using sodium N-methyl-N-phenyldithiocarbamate (L) and benzoylacetone (L'). The metal complexes were characterized by elemental analysis, electrical conductance, magnetic susceptibility, infrared (IR), and UV-visible spectroscopic studies. The electrical conductance measurements revealed the nonelectrolytic nature of the synthesized complexes. The results of the elemental analyses, magnetic susceptibility measurements, and electronic spectra inferred that the Zn(II) complex adopted a four-coordinate geometry while the Co(II), Cu(II), and Mn(II) complexes assumed octahedral geometries. The IR spectra showed that the metal ions coordinated with the ligands via the S- and O-donor atoms. The geometry, electronic, and thermodynamic parameters of the complexes were obtained from density functional theory (DFT) calculations. The spin density distributions, relative strength of H-bonds, and thermodynamic parameters revealed that the order of stability of the metal complexes is Mn < Co < Cu > Zn. The agar diffusion methods were used to study the antimicrobial activity of the complexes against two Gram positive bacteria (S. aureus and S. pneumoniae), one Gram negative bacterium (E. coli), and two fungi organisms (A. niger and A. candida) and the complexes showed a broad spectrum of activities against the microbes. PMID:26681931

  2. Inhibition of topoisomerase II by liriodenine.

    PubMed

    Woo, S H; Reynolds, M C; Sun, N J; Cassady, J M; Snapka, R M

    1997-08-15

    The cytotoxic oxoaporphine alkaloid liriodenine, isolated from Cananga odorata, was found to be a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro. Liriodenine treatment of SV40 (simian virus 40)-infected CV-1 cells caused highly catenated SV40 daughter chromosomes, a signature of topoisomerase II inhibition. Strong catalytic inhibition of topoisomerase II by liriodenine was confirmed by in vitro assays with purified human topoisomerase II and kinetoplast DNA. Liriodenine also caused low-level protein-DNA cross-links to pulse-labeled SV40 chromosomes in vivo, suggesting that it may be a weak topoisomerase II poison. This was supported by the finding that liriodenine caused topoisomerase II-DNA cross-links in an in vitro assay for topoisomerase II poisons. Verapamil did not increase either liriodenine-induced protein-DNA cross-links or catalytic inhibition of topoisomerase II in SV40-infected cells. This indicates that liriodenine is not a substrate for the verapamil-sensitive drug efflux pump in CV-1 cells. PMID:9313773

  3. Angiotensin II disrupts inhibitory avoidance memory retrieval.

    PubMed

    Bonini, Juliana S; Bevilaqua, Lia R; Zinn, Carolina G; Kerr, Daniel S; Medina, Jorge H; Izquierdo, Iván; Cammarota, Martín

    2006-08-01

    The brain renin-angiotensin system (RAS) is involved in learning and memory, but the actual role of angiotensin II (A(II)) and its metabolites in this process has been difficult to comprehend. This has been so mainly due to procedural issues, especially the use of multi-trial learning paradigms and the utilization of pre-training intracerebroventricular infusion of RAS-acting compounds. Here, we specifically analyzed the action of A(II) in aversive memory retrieval using a hippocampal-dependent, one-trial, step-down inhibitory avoidance task (IA) in combination with stereotaxically localized intrahippocampal infusion of drugs. Rats bilaterally implanted with infusion cannulae aimed to the CA1 region of the dorsal hippocampus were trained in IA and tested for memory retention 24 h later. We found that when given into CA1 15 min before IA memory retention test, A(II), but not angiotensin IV or angiotensin(1-7) induced a dose-dependent and reversible amnesia without altering locomotor activity, exploratory behavior or anxiety state. The effect of A(II) was blocked in a dose-dependent manner by the A(II)-type 2 receptor (AT(2)) antagonist PD123319 but not by the A(II)-type 1 receptor (AT(1)) antagonist losartan. By themselves, neither PD123319 nor losartan had any effect on memory expression. Our data indicate that intra-CA1 A(II) hinders retrieval of avoidance memory through a process that involves activation of AT(2) receptors.

  4. Factors Associated With Protein-energy Malnutrition in Chronic Liver Disease: Analysis Using Indirect Calorimetry.

    PubMed

    Nishikawa, Hiroki; Yoh, Kazunori; Enomoto, Hirayuki; Iwata, Yoshinori; Kishino, Kyohei; Shimono, Yoshihiro; Hasegawa, Kunihiro; Nakano, Chikage; Takata, Ryo; Nishimura, Takashi; Aizawa, Nobuhiro; Sakai, Yoshiyuki; Ikeda, Naoto; Takashima, Tomoyuki; Ishii, Akio; Iijima, Hiroko; Nishiguchi, Shuhei

    2016-01-01

    We aimed to elucidate the incidence of protein-energy malnutrition (PEM) in patients with chronic liver disease and to identify factors linked to the presence of PEM.A total of 432 patients with chronic liver disease were analyzed in the current analysis. We defined patients with serum albumin level of ≤3.5 g/dL and nonprotein respiratory quotient (npRQ) value using indirect calorimetry less than 0.85 as those with PEM. We compared between patients with PEM and those without PEM in baseline characteristics and examined factors linked to the presence of PEM using univariate and multivariate analyses.There are 216 patients with chronic hepatitis, 123 with Child-Pugh A, 80 with Child-Pugh B, and 13 with Child-Pugh C. Six patients (2.8%) had PEM in patients with chronic hepatitis, 17 (13.8%) in patients with Child-Pugh A, 42 (52.5%) in patients with Child-Pugh B, and 10 (76.9%) in patients with Child-Pugh C (P < 0.001). Multivariate analysis revealed that Child-Pugh classification (P < 0.001), age ≥64 years (P = 0.0428), aspartate aminotransferase (AST) ≥40 IU/L (P = 0.0023), and branched-chain amino acid to tyrosine ratio (BTR) ≤5.2 (P = 0.0328) were independent predictors linked to the presence of PEM. On the basis of numbers of above risk factors (age, AST, and BTR), the proportions of patients with PEM were well stratified especially in patients with early chronic hepatitis or Child-Pugh A (n = 339, P < 0.0001), while the proportions of patients with PEM tended to be well stratified in patients with Child-Pugh B or C (n = 93, P = 0.0673).Age, AST, and BTR can be useful markers for identifying PEM especially in patients with early stage of chronic liver disease.

  5. Special issue "International CAWSES-II Symposium"

    NASA Astrophysics Data System (ADS)

    Yamamoto, Mamoru; Shiokawa, Kazuo; Nakamura, Takuji; Gopalswamy, Nat

    2016-02-01

    This special issue gathered papers from the International CAWSES-II Symposium (November 18-22, 2013 at Nagoya University, Japan). Climate and Weather of the Sun-Earth System II (CAWSES-II) is an international scientific program sponsored by Scientific Committee on Solar-Terrestrial Physics (SCOSTEP) that continued from 2009 to 2013. The program was established with the aim of significantly enhancing our understanding of the space environment and its impacts on life and society. The International CAWSES-II Symposium was successful with 388 presentations; and from that, 38 papers were published in this special issue. In this preface, we briefly discuss the contents of the special issue as well as the CAWSES-II review papers published in Progress in Earth and Planetary Science (PEPS) in 2014-2015.

  6. TRUPACT-II Operating and Maintenance Instructions

    SciTech Connect

    Westinghouse Electric Corporation, Waste Isolation Division

    1999-12-31

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package Transporter Model II (TRUPACT-II) Shipping Package and directly related components. This document complies with the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP) and Nuclear Regulatory Commission (NRC) Certificate of Compliance (C of C) 9218. In the event there is a conflict between this document and the TRUPACT-II SARP, the TRUPACT-II SARP shall govern. TRUPACT-II C of C number 9218 states, ''... each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application.'' It further states, ''... each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the application.'' Chapter 9 of the TRUPACT-II SARP charges the Westinghouse Electric Corporation Waste Isolation Division (WID) with assuring that the TRUPACT-II is used in accordance with the requirements of the C of C. To meet this requirement and verify consistency of operations when loading and unloading the TRUPACT-II on the trailer, placing a payload in the packaging, unloading the payload from the packaging, or performing maintenance, the U.S. Department of Energy Carlsbad Area Office (U.S. DOE/CAO) finds it necessary to implement the changes that follow. This TRUPACT-II maintenance document represents a change to previous philosophy regarding site specific procedures for the use of the TRUPACT-II. This document details the instructions to be followed to consistently operate and maintain the TRUPACT-II. The intent of these instructions is to ensure that all users of the TRUPACT-II follow the same or equivalent instructions. Users may achieve this intent by any of the following methods: (1) Utilizing these instructions as is, or (2

  7. TRUPACT-II, a regulatory perspective

    SciTech Connect

    Gregory, P.C.; Spooner, O.R.

    1995-12-31

    The Transuranic Package Transporter II (TRUPACT-II) is a US Nuclear Regulatory Commission (NRC) certified Type B packaging for the shipment of contact-handled transuranic (CH-TRU) material by the US Department of Energy (DOE). The NRC approved the TRUPACT-II design as meeting the requirements of Title 10, Code of Federal Regulations, Part 71 (10 CFR 71) and issued Certificate of Compliance (CofC) Number 9218 to the DOE. There are currently 15 certified TRUPACT-IIs. Additional TRUPACT-IIs will be required to make more than 15,000 shipments of CH-TRU waste to the Waste Isolation Pilot Plant (WIPP) site near Carlsbad, New Mexico. The TRUPACT-II may also be used for the DOE inter-site and intra-site shipments of CH-TRU waste. The Land Withdrawal Act (Public Law 102-579), enacted by the US Congress, October 30, 1992, and an agreement between the DOE and the State of New Mexico, signed August 4, 1987, both stipulate that only NRC approved packaging may be used for shipments of TRU waste to the WIPP. Early in the TRUPACT-II development phase it was decided that the transportation system (tractor, trailer, and TRUPACT-II) should be highway legal on all routes without the need for oversize and/or overweight permits. In large measure, public acceptance of the DOE`s efforts to safely transport CH-TRU waste depends on the public`s perception that the TRUPACT-II is in compliance with all applicable regulations, standards, and quality assurance requirements. This paper addresses some of the numerous regulations applicable to Type B packaging, and it describes how the TRUPACT-II complies with these regulations.

  8. Intracellular angiotensin II activates rat myometrium.

    PubMed

    Deliu, Elena; Tica, Andrei A; Motoc, Dana; Brailoiu, G Cristina; Brailoiu, Eugen

    2011-09-01

    Angiotensin II is a modulator of myometrial activity; both AT(1) and AT(2) receptors are expressed in myometrium. Since in other tissues angiotensin II has been reported to activate intracellular receptors, we assessed the effects of intracellular administration of angiotensin II via microinjection on myometrium, using calcium imaging. Intracellular injection of angiotensin II increased cytosolic Ca(2+) concentration ([Ca(2+)](i)) in myometrial cells in a dose-dependent manner. The effect was abolished by the AT(1) receptor antagonist losartan but not by the AT(2) receptor antagonist PD-123319. Disruption of the endo-lysosomal system, but not that of Golgi apparatus, prevented the angiotensin II-induced increase in [Ca(2+)](i). Blockade of AT(1) receptor internalization had no effect, whereas blockade of microautophagy abolished the increase in [Ca(2+)](i) produced by intracellular injection of angiotensin II; this indicates that microautophagy is a critical step in transporting the peptide into the endo-lysosomes lumenum. The response to angiotensin II was slightly reduced in Ca(2+)-free saline, indicating a major involvement of Ca(2+) release from internal stores. Blockade of inositol 1,4,5-trisphosphate (IP(3)) receptors with heparin and xestospongin C or inhibition of phospholipase C (PLC) with U-73122 abolished the response to angiotensin II, supporting the involvement of PLC-IP(3) pathway. Angiotensin II-induced increase in [Ca(2+)](i) was slightly reduced by antagonism of ryanodine receptors. Taken together, our results indicate for the first time that in myometrial cells, intracellular angiotensin II activates AT(1)-like receptors on lysosomes and activates PLC-IP(3)-dependent Ca(2+) release from endoplasmic reticulum; the response is further augmented by a Ca(2+)-induced Ca(2+) release mechanism via ryanodine receptors activation.

  9. Standards in neurosonology. Part II

    PubMed Central

    Tomczyk, Tomasz; Luchowski, Piotr; Kozera, Grzegorz; Kaźmierski, Radosław; Stelmasiak, Zbigniew

    2016-01-01

    The paper presents standards related to ultrasound imaging of the cerebral vasculature and structures. The aim of this paper is to standardize both the performance and description of ultrasound imaging of the extracranial and intracranial cerebral arteries as well as a study of a specific brain structure, i.e. substantia nigra hyperechogenicity. The following aspects are included in the description of standards for each ultrasonographic method: equipment requirements, patient preparation, study technique and documentation as well as the required elements of ultrasound description. Practical criteria for the diagnosis of certain pathologies in accordance with the latest literature were also presented. Furthermore, additional comments were included in some of the sections. Part I discusses standards for the performance, documentation and description of different ultrasound methods (Duplex, Doppler). Part II and III are devoted to standards for specific clinical situations (vasospasm, monitoring after the acute stage of stroke, detection of a right-to-left shunts, confirmation of the arrest of the cerebral circulation, an assessment of the functional efficiency of circle of Willis, an assessment of the cerebrovascular vasomotor reserve as well as the measurement of substantia nigra hyperechogenicity). PMID:27104002

  10. Ozone Conference II: Abstract Proceedings

    SciTech Connect

    1999-11-01

    Ozone Conference II: Pre- and Post-Harvest Applications Two Years After Gras, was held September 27-28, 1999 in Tulare, California. This conference, sponsored by EPRI's Agricultural Technology Alliance and Southern California Edison's AgTAC facility, was coordinated and organized by the on-site ATA-AgTAC Regional Center. Approximately 175 people attended the day-and-a-half conference at AgTAC. During the Conference twenty-two presentations were given on ozone food processing and agricultural applications. Included in the presentations were topics on: (1) Ozone fumigation; (2) Ozone generation techniques; (3) System and design applications; (4) Prewater treatment requirements; (5) Poultry water reuse; (6) Soil treatments with ozone gas; and (7) Post-harvest aqueous and gaseous ozone research results. A live videoconference between Tulare and Washington, D.C. was held to discuss the regulators' view from inside the beltway. Attendees participated in two Roundtable Question and Answer sessions and visited fifteen exhibits and demonstrations. The attendees included university and governmental researchers, regulators, consultants and industry experts, technology developers and providers, and corporate and individual end-users. This report is comprised of the Abstracts of each presentation, biographical sketches for each speaker and a registration/attendees list.

  11. Standards in neurosonology. Part II.

    PubMed

    Wojczal, Joanna; Tomczyk, Tomasz; Luchowski, Piotr; Kozera, Grzegorz; Kaźmierski, Radosław; Stelmasiak, Zbigniew

    2016-03-01

    The paper presents standards related to ultrasound imaging of the cerebral vasculature and structures. The aim of this paper is to standardize both the performance and description of ultrasound imaging of the extracranial and intracranial cerebral arteries as well as a study of a specific brain structure, i.e. substantia nigra hyperechogenicity. The following aspects are included in the description of standards for each ultrasonographic method: equipment requirements, patient preparation, study technique and documentation as well as the required elements of ultrasound description. Practical criteria for the diagnosis of certain pathologies in accordance with the latest literature were also presented. Furthermore, additional comments were included in some of the sections. Part I discusses standards for the performance, documentation and description of different ultrasound methods (Duplex, Doppler). Part II and III are devoted to standards for specific clinical situations (vasospasm, monitoring after the acute stage of stroke, detection of a right-to-left shunts, confirmation of the arrest of the cerebral circulation, an assessment of the functional efficiency of circle of Willis, an assessment of the cerebrovascular vasomotor reserve as well as the measurement of substantia nigra hyperechogenicity).

  12. Early failure of Class II resin composite versus Class II amalgam restorations placed by dental students.

    PubMed

    Overton, J D; Sullivan, Diane J

    2012-03-01

    Using the information from remake request slips in a dental school's predoctoral clinic, we examined the short-term survival of Class II resin composite restorations versus Class II dental amalgam restorations. In the student clinic, resin composite is used in approximately 58 percent of Class II restorations placed, and dental amalgam is used in the remaining 42 percent. In the period examined, Class II resin composite restorations were ten times more likely to be replaced at no cost to the patient than Class II dental amalgam restorations. A total of eighty-four resin composite restorations and six amalgam restorations were replaced due to an identified failure.

  13. [Transarterial infusion chemotherapy using fine-powder cisplatin in patients with advanced hepatocellular carcinoma].

    PubMed

    Hatanaka, Takeshi; Kakizaki, Satoru; Ueno, Takashi; Takeuchi, Suguru; Takizawa, Daichi; Katakai, Kenji

    2014-02-01

    We investigated the therapeutic effects and safety of fine powder cisplatin for patients with advanced hepatocellular carcinoma( HCC). From January 2006 to March 2012, 123 patients with advanced HCC were treated by transarterial infusion chemotherapy(TAI)with fine-powder cisplatin(IA-call®, Nippon Kayaku Co. Ltd., Tokyo, Japan). The drug was infused into the liver through the feeding artery at a dose of 65 mg/m2. The treatment was repeated every 4 to 8 weeks until evidence of either tumor progression or unacceptable toxicity appeared. Treatment responses were classified as complete response(CR), partial response(PR), stable disease(SD), and progressive disease(PD)in 3.2%, 12.0%, 32.2%, and 52.4% of patients, respectively. The median survival durations were as follows: overall, 12.2 months; CR/PR patients, 23.8 months; and SD/PD patients, 10.6 months. The cumulative survival rates of CR/PR patients were significantly higher than those of SD/PD patients (p<0.05). Multivariate analyses revealed that treatment response, etiology, Child-Pugh grading, and level of protein induced by the vitamin K antagonist- II (PIVKA- II )were predictive factors of survival duration. Problematic adverse events were not observed in any of the patients. Our results suggest that TAI using fine-powder cisplatin can be safely administered for advanced HCC and can improve the prognosis of patients with advanced disease. PMID:24743198

  14. Survival outcomes after stereotactic body radiotherapy for 79 Japanese patients with hepatocellular carcinoma.

    PubMed

    Yamashita, Hideomi; Onishi, Hiroshi; Murakami, Naoya; Matsumoto, Yasuo; Matsuo, Yukinori; Nomiya, Takuma; Nakagawa, Keiichi

    2015-05-01

    Stereotactic body radiotherapy (SBRT) is a relatively new treatment for liver tumor. Outcomes of SBRT for liver tumors unsuitable for ablation or surgical resection were evaluated. A total of 79 patients treated with SBRT for primary hepatocellular carcinoma (HCC) between 2004 and 2012 in six Japanese institutions were studied retrospectively. Patients treated with SBRT preceded by trans-arterial chemoembolization were eligible. Their median age was 73 years, 76% were males, and their Child-Pugh scores were Grades A (85%) and B (11%) before SBRT. The median biologically effective dose (α/β = 10 Gy) was 96.3 Gy. The median follow-up time was 21.0 months for surviving patients. The 2-year overall survival (OS), progression-free survival (PFS), and distant metastasis-free survival were 53%, 40% and 76%, respectively. Sex and serum PIVKA-II values were significant predictive factors for OS. Hypovascular or hypervascular types of HCC, sex and clinical stage were significant predictive factors for PFS. The 2-year PFS was 66% in Stage I vs 18% in Stages II-III. Multivariate analysis indicated that clinical stage was the only significant predictive factor for PFS. No Grade 3 laboratory toxicities in the acute, sub-acute, and chronic phases were observed. PFS after SBRT for liver tumor was satisfactory, especially for Stage I HCC, even though these patients were unsuitable for resection and ablation. SBRT is safe and might be an alternative to resection and ablation. PMID:25691453

  15. Adsorption of Cu(II), Hg(II), and Ni(II) ions by modified natural wool chelating fibers.

    PubMed

    Monier, M; Ayad, D M; Sarhan, A A

    2010-04-15

    The graft copolymerization of ethyl acrylate (EA) onto natural wool fibers initiated by potassium persulphate and Mohr's salt redox initiator system in limited aqueous medium was carried out in heterogeneous media. Ester groups of the grafted copolymers were partially converted into hydrazide function groups followed by hydrazone formation through reaction with isatin. Also the application of the modified fibers for metal ion uptake was studied using Cu(II), Hg(II) and Ni(II). The modified chelating fibers were characterized using FTIR spectroscopy, SEM and X-ray diffraction. PMID:19962235

  16. Effects of Mg II and Ca II ionization on ab-initio solar chromosphere models

    NASA Technical Reports Server (NTRS)

    Rammacher, W.; Cuntz, M.

    1991-01-01

    Acoustically heated solar chromosphere models are computed considering radiation damping by (non-LTE) emission from H(-) and by Mg II and Ca II emission lines. The radiative transfer equations for the Mg II k and Ca II K emission lines are solved using the core-saturation method with complete redistribution. The Mg II k and Ca II K cooling rates are compared with the VAL model C. Several substantial improvements over the work of Ulmschneider et al. (1987) are included. It is found that the rapid temperature rises caused by the ionization of Mg II are not formed in the middle chromosphere, but occur at larger atmospheric heights. These models represent the temperature structure of the 'real' solar chromosphere much better. This result is a major precondition for the study of ab-initio models for solar flux tubes based on MHD wave propagation and also for ab-initio models for the solar transition layer.

  17. [C II] and [N II] from dense ionized regions in the Galaxy

    NASA Astrophysics Data System (ADS)

    Langer, W. D.; Goldsmith, P. F.; Pineda, J. L.

    2016-05-01

    Context. The interstellar medium (ISM) consists of highly ionized and neutral atomic, as well as molecular, components. Knowledge of their distribution is important for tracing the structure and lifecycle of the ISM. Aims: To determine the properties of the highly ionized gas and neutral weakly ionized gas in the Galaxy traced by the fine-structure lines of ionized nitrogen, [N ii], and ionized carbon, [C ii]. Methods: We utilize observations of the [C ii] 158 μm and [N ii] 205 μm fine-structure lines taken with the high spectral resolution Heterodyne Instrument in the Far-Infrared (HIFI) on the Herschel Space Observatory along ten lines of sight towards the inner Galaxy to analyze the ionized ISM. The [N ii] emission can be used to estimate the contribution of the highly ionized gas to the [C ii] emission and separate the contributions from highly ionized and weakly ionized neutral gas. Results: We find that [N ii] has strong emission in distinct spectral features along all lines of sight associated with strong [C ii] emission. The [N ii] arises from moderate density extended H ii regions or ionized boundary layers of clouds. Comparison of the [N ii] and [C ii] spectra in 31 separate kinematic features shows that many of the [C ii] spectra are affected by absorption from low excitation gas associated with molecular clouds, sometimes strongly so. The apparent fraction of the [C ii] associated with the [N ii] gas is unrealistically large in many cases, most likely due to the reduction of [C ii] by absorption. In a few cases the foreground absorption can be modeled to determine the true source intensity. In these sources we find that the foreground absorbing gas layer has C+ column densities of order 1018 cm-2. Conclusions: [C ii] emission arising from strong sources of [N ii] emission is frequently absorbed by low excitation foreground gas complicating the interpretation of the properties of the ionized and neutral gas components that give rise to [C ii] emission.

  18. New Rh2(II,II) Architecture for the Catalytic Reduction of H⁺.

    PubMed

    White, Travis A; Witt, Suzanne E; Li, Zhanyong; Dunbar, Kim R; Turro, Claudia

    2015-10-19

    Formamidinate-bridged Rh2(II,II) complexes containing diimine ligands of the formula cis-[Rh2(II,II)(μ-DTolF)2(NN)2](2+) (Rh2-NN2), where DTolF = p-ditolylformamidinate and NN = dppn (benzo[i]dipyrido[3,2-a:2',3'-h]quinoxaline), dppz (dipyrido[3,2-a:2',3'-c]phenazine), and phen (1,10-phenanthroline), electrocatalytically reduce H(+) to H2 in DMF solutions containing CH3COOH at a glassy carbon electrode. Cathodic scans in the absence of acid display a Rh(III,II/II,II) reduction at -0.90 V vs Fc(+)/Fc followed by NN(0/-) reduction at -1.13, -1.36, and -1.65 V for Rh2-dppn2, Rh2-dppz2, and Rh2-phen2, respectively. Upon the addition of acid, Rh2-dppn2 and Rh2-dppz2 undergo reduction-protonation-reduction at each pyrazine-containing NN ligand prior to the Rh2(II,II/II,I) reduction. The Rh2(II,I) species is then protonated at one of the metal centers, resulting in the formation of the corresponding Rh2(II,III)-hydride. In the case of Rh2-phen2, the reduction of the phen ligand is followed by intramolecular electron transfer to the Rh2(II,II) core in the presence of protons to form a Rh2(II,III)-hydride species. Further reduction and protonation at the Rh2 core for all three complexes rapidly catalyzes H2 formation with varied calculated turnover frequencies (TOF) and overpotential values (η): 2.6 × 10(4) s(-1) and 0.56 V for Rh2-dppn, 2.8 × 10(4) s(-1) and 0.50 V for Rh2-dppz2, and 5.9 × 10(4) s(-1) and 0.64 V for Rh2-phen2. Bulk electrolysis confirmed H2 formation, and further CH3COOH addition regenerates H2 production, attesting to the robust nature of the architecture. The cis-[Rh2(II,II)(μ-DTolF)2(NN)2](2+) architecture benefits by combining electron-rich formamidinate bridges, a redox-active Rh2(II,II) core, and electron-accepting NN diimine ligands to allow for the electrocatalysis of H(+) substrate to H2 fuel.

  19. Chitosan film loaded with silver nanoparticles-sorbent for solid phase extraction of Al(III), Cd(II), Cu(II), Co(II), Fe(III), Ni(II), Pb(II) and Zn(II).

    PubMed

    Djerahov, Lubomir; Vasileva, Penka; Karadjova, Irina; Kurakalva, Rama Mohan; Aradhi, Keshav Krishna

    2016-08-20

    The present study describes the ecofriendly method for the preparation of chitosan film loaded with silver nanoparticles (CS-AgNPs) and application of this film as efficient sorbent for separation and enrichment of Al(III), Cd(II), Cu(II), Co(II), Fe(III), Ni(II), Pb(II) and Zn(II). The stable CS-AgNPs colloid was prepared by dispersing the AgNPs sol in chitosan solution at appropriate ratio and further used to obtain a cast film with very good stability under storage and good mechanical strength for easy handling in aqueous medium. The incorporation of AgNPs in the structure of CS film and interaction between the polymer matrix and nanoparticles were confirmed by UV-vis and FTIR spectroscopy. The homogeneously embedded AgNPs (average diameter 29nm, TEM analysis) were clearly observed throughout the film by SEM. The CS-AgNPs nanocomposite film shows high sorption activity toward trace metals under optimized chemical conditions. The results suggest that the CS-AgNPs nanocomposite film can be feasibly used as a novel sorbent material for solid-phase extraction of metal pollutants from surface waters.

  20. SEARCHING FOR NEW HYPERCOMPACT H II REGIONS

    SciTech Connect

    Sanchez-Monge, Alvaro; Pandian, Jagadheep D.; Kurtz, Stan

    2011-09-20

    Hypercompact (HC) H II regions are, by nature, very young H II regions, associated with the earliest stages of massive star formation. They may represent the transition phase as an early B-type star grows into an O-type star. Unfortunately, so few HC H II regions are presently known that their general attributes and defining characteristics are based on small number statistics. A larger sample is needed for detailed studies and good statistics. Class II methanol masers are one of the best indicators of the early stages of massive star formation. Using the Arecibo Methanol Maser Galactic Plane Survey-the most sensitive blind survey for 6.7 GHz methanol masers to date-we selected 24 HC H II region candidates. We made Expanded Very Large Array continuum observations at 3.6 and 1.3 cm to search for HC H II regions associated with these masers. We identified six potential HC H II regions in our sample based on the presence of optically thick free-free emission. Overall, we find that 30% of the methanol masers have an associated centimeter radio continuum source (separation less than 0.1 pc), which is in general agreement with previous studies.

  1. Angiotensin II: Immunohistochemical Study in Sardinian Pterygium

    PubMed Central

    Demurtas, P.; Corrias, M.; Zucca, I.; Piras, F.; Sirigu, P.; Perra, M.T.

    2014-01-01

    The Angiotensin II (Ang II) is the principal effector peptide of the RAS system. It has a pleiotropic effect and, beside its physiological role, it has the property to stimulate angiogenesis and activate multiple signalling pathways related to cell proliferation. The purpose of the study was to determinate the Ang II expression and localization in Sardinian pterygium and normal conjunctiva by immunohistochemistry, and its possible involvement in the development and progression of the disease. Twenty-three pterygiums and eleven normal conjunctiva specimens obtained from Sardinian patients, were processed for paraffin embedding and assessed for the immunohistochemi-cal revelation of Ang II. Significant Ang II expression was identified in pterygium and conjunctiva. Particularly, thirteen pterygium specimens (n=13) displayed exclusively moderate to strong nuclear staining; some specimens (n=5) showed exclusively a moderate cytoplasmic immunoreactivity, and few specimens (n=2) displayed moderate to strong immunoreactivity in both cytoplasm and nucleus. Only 3 specimens were negative. Statistical significance difference in respect of nuclear and cytoplasmic localization was observed between normal conjunctiva and pterygium (P=0.020). The results showed a predominant intranuclear localization of Ang II in pterygium epithelial cells, in spite of conjunctiva that mainly showed cytoplasmic localization. These findings suggest a possible role for Ang II in the development and/or progression of pterygium mediated by the activation of local RAS system. PMID:25308851

  2. 20 CFR 404.1342 - Limits on granting World War II and post-World War II wage credits.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Limits on granting World War II and post-World War II wage credits. 404.1342 Section 404.1342 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... II and post-World War II wage credits. (a) You get wage credits for World War II or post-World......

  3. 20 CFR 404.1342 - Limits on granting World War II and post-World War II wage credits.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Limits on granting World War II and post-World War II wage credits. 404.1342 Section 404.1342 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... II and post-World War II wage credits. (a) You get wage credits for World War II or post-World......

  4. 20 CFR 404.1342 - Limits on granting World War II and post-World War II wage credits.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Limits on granting World War II and post-World War II wage credits. 404.1342 Section 404.1342 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... II and post-World War II wage credits. (a) You get wage credits for World War II or post-World......

  5. 20 CFR 404.1342 - Limits on granting World War II and post-World War II wage credits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Limits on granting World War II and post-World War II wage credits. 404.1342 Section 404.1342 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... II and post-World War II wage credits. (a) You get wage credits for World War II or post-World......

  6. 20 CFR 404.1342 - Limits on granting World War II and post-World War II wage credits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Limits on granting World War II and post-World War II wage credits. 404.1342 Section 404.1342 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... II and post-World War II wage credits. (a) You get wage credits for World War II or post-World......

  7. Probing Our Heliospheric History II

    NASA Astrophysics Data System (ADS)

    Wyman, Katherine; Redfield, S.

    2012-05-01

    A physical relationship between our local interstellar medium (ISM), galactic cosmic rays (GCR), and our planetary environment has long been a subject of interest to the astronomical community. Clouds of sufficient density to compress the heliosphere to within 1 AU are commonly seen throughout the galactic environment, including within the Local Bubble (LB). Such a compression would lead to an increase in the GCR flux at 1 AU and would have drastic consequences for many planetary processes such as atmospheric chemistry, lightning production, cloud cover, and DNA mutation rates for surface organisms. Prior to this work, we derived a column density profile of the ISM toward 49 bright stars along a narrow cone centered on the historical solar path. High resolution spectra were taken of NaI and CaII absorption out to a distance of 610 pc, with a median separation distance of 11 pc between adjacent stars. No absorption is seen out to a distance of 120 pc (consistent with the LB), but a complex number of absorbers is seen beyond. We now present the detection of several distinct clouds, their associated column densities, radial velocities, inferred distances, and size constraints. This combination of cloud properties allows us to derive a volume density profile of the ISM in the Sun's “rear-view mirror,” which represents one plausible record of actual ISM encounters for the Sun. We also make use of empirical relations to determine the effect these clouds would have on the historical heliosphere. Our analysis suggests that within the last 10 million years, if the Sun encountered a cloud with the same properties as we have detected along the solar historical trajectory, the Sun's termination shock would have resided inside the orbit of Uranus, with a GCR flux at Earth an order of magnitude greater than it is currently.

  8. Angiotensin II receptors in testes

    SciTech Connect

    Millan, M.A.; Aguilera, G.

    1988-05-01

    Receptors for angiotensin II (AII) were identified and characterized in testes of rats and several primate species. Autoradiographic analysis of the binding of 125I-labeled (Sar1,Ile8)AII to rat, rhesus monkey, cebus monkey, and human testicular slide-mounted frozen sections indicated specific binding to Leydig cells in the interstitium. In rat collagenase-dispersed interstitial cells fractionated by Percoll gradient, AII receptor content was parallel to that of hCG receptors, confirming that the AII receptors are in the Leydig cells. In rat dispersed Leydig cells, binding was specific for AII and its analogs and of high affinity (Kd, 4.8 nM), with a receptor concentration of 15 fmol/10(6) cells. Studies of AII receptors in rat testes during development reveals the presence of high receptor density in newborn rats which decreases toward the adult age (4934 +/- 309, 1460 +/- 228, 772 +/- 169, and 82 +/- 12 fmol/mg protein at 5, 15, 20, and 30 days of age, respectively) with no change in affinity. At all ages receptors were located in the interstitium, and the decrease in binding was parallel to the decrease in the interstitial to tubular ratio observed with age. AII receptor properties in membrane-rich fractions from prepuberal testes were similar in the rat and rhesus monkey. Binding was time and temperature dependent, reaching a plateau at 60 min at 37 C, and was increased by divalent cations, EGTA, and dithiothreitol up to 0.5 mM. In membranes from prepuberal monkey testes, AII receptors were specific for AII analogs and of high affinity (Kd, 4.2 nM) with a receptor concentration of 7599 +/- 1342 fmol/mg protein. The presence of AII receptors in Leydig cells in rat and primate testes in conjunction with reports of the presence of other components of the renin-angiotensin system in the testes suggests that the peptide has a physiological role in testicular function.

  9. Light harvesting in photosystem II.

    PubMed

    van Amerongen, Herbert; Croce, Roberta

    2013-10-01

    Water oxidation in photosynthesis takes place in photosystem II (PSII). This photosystem is built around a reaction center (RC) where sunlight-induced charge separation occurs. This RC consists of various polypeptides that bind only a few chromophores or pigments, next to several other cofactors. It can handle far more photons than the ones absorbed by its own pigments and therefore, additional excitations are provided by the surrounding light-harvesting complexes or antennae. The RC is located in the PSII core that also contains the inner light-harvesting complexes CP43 and CP47, harboring 13 and 16 chlorophyll pigments, respectively. The core is surrounded by outer light-harvesting complexes (Lhcs), together forming the so-called supercomplexes, at least in plants. These PSII supercomplexes are complemented by some "extra" Lhcs, but their exact location in the thylakoid membrane is unknown. The whole system consists of many subunits and appears to be modular, i.e., both its composition and organization depend on environmental conditions, especially on the quality and intensity of the light. In this review, we will provide a short overview of the relation between the structure and organization of pigment-protein complexes in PSII, ranging from individual complexes to entire membranes and experimental and theoretical results on excitation energy transfer and charge separation. It will become clear that time-resolved fluorescence data can provide invaluable information about the organization and functioning of thylakoid membranes. At the end, an overview will be given of unanswered questions that should be addressed in the near future.

  10. Participation of angiotensin II in learning and memory. II. Interactions of angiotensin II with dopaminergic drugs.

    PubMed

    Yonkov, D I; Georgiev, V P; Opitz, M J

    1986-04-01

    The effect of angiotensin II (ATII) and of its interactions with dopaminergic drugs injected post-trial on retention in active avoidance tasks in shuttle-box-trained rats were studied. ATII at doses of 0.10 and 0.50 micrograms administered intracerebroventricularly (i.c.v.) immediately after training improved retention. The dopaminergic receptor agonist apomorphine at a dose of 0.10 mg/kg injected intraperitoneally (i.p.) facilitated retention whereas elymoclavine (a dopaminergic agonist) at a dose of 2.5 mg/kg i.p. had no effect. ATII at a dose of 0.10 micrograms i.c.v. administered after apomorphine 0.10 mg/kg or elymoclavine 2.5 mg/kg exerted a stronger retention-facilitating effect. The dopaminergic receptor antagonist haloperidol at a dose of 1 mg/kg i.p. markedly impaired retention. ATII at a dose of 0.50 micrograms administered after haloperidol (1 mg/kg) did not exercise its retention-facilitating effect. It is concluded that the retention facilitating effects of ATII are realized through interactions with brain dopaminergic transmission.

  11. Indium-111-Photofrin-II scintillation scan

    SciTech Connect

    Origitano, T.C.; Karesh, S.M.; Reichman, O.H.; Henkin, R.E.; Caron, M.J.

    1989-04-01

    Photodynamic therapy is under intense investigation as an adjuvant treatment for malignant glial tumors of the central nervous system. Photofrin-II (HpD-II) is currently the most actively investigated photosensitizing agent. A crucial issue regarding the safe and efficacious usage of HpD-II-based photodynamic therapy is the individual in vivo kinetics of tumor uptake and retention, compared with normal brain clearance. The optimal time for photoactivation of sensitized tumor must be known to ensure a high target-to-nontarget ratio, resulting in the maximal tumor destruction while preserving normal brain. Our laboratory developed a radionuclide scan based on 111indium (111In)-labeled HpD-II to evaluate HpD-II localization and clearance noninvasively within a canine model of intracerebral gliosarcoma. Synthesis of the 111In-HpD-II complex in greater than 90% yield is achieved by a simple, rapid labeling method. Radiochemical purity and stability were verified by high-performance liquid chromatography. Using the canine model of intracerebral gliosarcoma, we followed the uptake of 111In-HpD-II in tumors with serial scintillation scanning. Localization of the tumor by 111In-HpD-II has been verified by contrast-enhanced computed tomographic scan followed by gross and histological examination of the enhancing brain region. Total body biodistribution of 111In-HpD-II at various times after injection has been evaluated. The ratio of uptake in tumor compared with surrounding brain peaked at 72 hours after injection. The knowledge of regional distribution and concentration of a photosensitizing agent within a tumor mass and surrounding brain allows for the most efficacious timing and localization of a photoactivating source.

  12. Angiotensin II and renal tubular ion transport.

    PubMed

    Valles, Patricia; Wysocki, Jan; Batlle, Daniel

    2005-08-29

    Angiotensin II, a potent vasoconstrictor, also participates in the regulation of renal sodium and water excretion, not only via a myriad of effects on renal hemodynamics, glomerular filtration rate, and regulation of aldosterone secretion, but also via direct effects on renal tubule transport. In addition, angiotensin II stimulates H+ secretion and HCO3- reabsorption in both proximal and distal tubules and regulates H+-ATPase activity in intercalated cells of the collecting tubule. Different results regarding the effect of angiotensin II on bicarbonate reabsorption and proton secretion have been reported at the functional level, depending on the angiotensin II concentration and tubule segment studied. It is likely that interstitial angiotensin II is more important in regulating hemodynamic and transport functions than circulating angiotensin II. In proximal tubules, stimulation of bicarbonate reabsorption, Na+/H+-exchange, and Na+/HCO3- cotransport has been found using low concentrations (<10(-9) M), while inhibition of bicarbonate reabsorption has been documented using concentrations higher than 10(-8) M. Evidence for the regulation of H+-ATPase activity in vivo and in vitro by trafficking/exocytosis has been provided. An additional level of H+-ATPase regulation via protein synthesis may be important as well. Recently, we have shown that both aldosterone and angiotensin II provide such a mechanism of regulation in vivo at the level of the medullary collecting tubule. Interestingly, in this part of the nephron, the effects of aldosterone and angiotensin II are not sodium dependent, whereas in the cortical collecting duct, both aldosterone and angiotensin II, by contrast, affect H+ secretion by sodium-dependent mechanisms.

  13. Angiotensin II reduces calcium uptake into bone.

    PubMed

    Schurman, Scott J; Bergstrom, William H; Shoemaker, Lawrence R; Welch, Thomas R

    2004-01-01

    Children with neonatal Bartter syndrome (NBS) have hypercalciuria, nephrocalcinosis, and osteopenia. A complex of basic-fibroblast growth factor (b-FGF) and a naturally occurring glycosaminoglycan has been identified in the serum and urine of NBS patients. This complex increases bone resorption in a bone disc bioassay system. Angiotensin II (AT II), which is increased in Bartter syndrome, increases the synthesis of b-FGF by cultured endothelial cells. Addition of 10(-8) M AT II to the bioassay, a concentration reported in Bartter syndrome patients, significantly decreased calcium uptake into bone discs [E/C 0.60 (0.04), P < 0.001 compared with buffer, normal E/C >0.90]. Adding b-FGF monoclonal antibody at 10 microg/ml [E/C 0.90 (0.06), P=NS] or indomethacin [E/C 1.00 (0.03), P=NS] to 10(-8 )M AT II neutralized this effect. In separate experiments, newborn rats were given intraperitoneal injections of AT II. Bone discs from these animals were used in the bioassay system and calcium uptake was markedly reduced compared with discs from rats injected with phosphate-buffered saline [AT II 6.6 x 10(-9), E/C 0.10 (0.04), P<0.001, AT II 3.3 x 10(-8), E/C 0.10 (0.05), P<0.001]. AT II decreases calcium uptake in the bone disc bioassay system. This effect can be abrogated by antibody to b-FGF or prostaglandin synthetase inhibition. These results support the hypothesis that in children with NBS, elevated levels of AT II stimulate local skeletal b-FGF synthesis, with a resultant increase in bone resorption via a prostaglandin-dependent pathway. PMID:14648327

  14. Delta II development and flight results

    NASA Astrophysics Data System (ADS)

    Mihara, S. K.

    An account is given of the design modifications of the Delta launch vehicle which have resulted in its Delta II variant, together with flight results obtained with the Delta II to date. Delta II launchers feature a stretched LX tank, a larger-diameter satellite-payload fairing, and an expansion of first-stage nozzle expansion ratio from 8:1 to 12:1. The thrust-augmenting solid rocket boosters use graphite/epoxy composite motor cases. Both two-stage and three-stage launches are discussed, with attention to flights for the Navstar satellites.

  15. LHC II system sensitivity to magnetic fluids

    NASA Astrophysics Data System (ADS)

    Cotae, Vlad; Creanga, Ioan

    2005-03-01

    Experiments have been designed to reveal the influences of ferrofluid treatment and static magnetic field exposure on the photosynthetic system II, where the light harvesting complex (LHC II) controls the ratio chlorophyll a/ chlorophyll b (revealing, indirectly, the photosynthesis rate). Spectrophotometric measurement of chlorophyll content revealed different influences for relatively low ferrofluid concentrations (10-30 μl/l) in comparison to higher concentrations (70-100 μl/l). The overlapped effect of the static magnetic field shaped better the stimulatory ferrofluid action on LHC II system in young poppy plantlets.

  16. Synthesis, characterization and anti-microbial evaluation of Cu(II), Ni(II), Pt(II) and Pd(II) sulfonylhydrazone complexes; 2D-QSAR analysis of Ni(II) complexes of sulfonylhydrazone derivatives

    NASA Astrophysics Data System (ADS)

    Özbek, Neslihan; Alyar, Saliha; Alyar, Hamit; Şahin, Ertan; Karacan, Nurcan

    2013-05-01

    Copper(II), nickel(II), platinum(II) and palladium(II) complexes with 2-hydroxy-1-naphthaldehyde-N-methylpropanesulfonylhydrazone (nafpsmh) derived from propanesulfonic acid-1-methylhydrazide (psmh) were synthesized, their structure were identified, and antimicrobial activity of the compounds was screened against three Gram-positive and three Gram-negative bacteria. The results of antimicrobial studies indicate that Pt(II) and Pd(II) complexes showed the most activity against all bacteria. The crystal structure of 2-hydroxy-1-naphthaldehyde-N-methylpropanesulfonylhydrazone (nafpsmh) was also investigated by X-ray analysis. A series of Ni(II) sulfonyl hydrazone complexes (1-33) was synthesized and tested in vitro against Escherichia coli and Staphylococcus aureus. Their antimicrobial activities were used in the QSAR analysis. Four-parameter QSAR models revealed that nucleophilic reaction index for Ni and O atoms, and HOMO-LUMO energy gap play key roles in the antimicrobial activity.

  17. Genetics Home Reference: mucolipidosis II alpha/beta

    MedlinePlus

    ... Health Conditions mucolipidosis II alpha/beta mucolipidosis II alpha/beta Enable Javascript to view the expand/collapse ... PDF Open All Close All Description Mucolipidosis II alpha/beta (also known as I-cell disease) is ...

  18. Genetics Home Reference: distal hereditary motor neuropathy, type II

    MedlinePlus

    ... hereditary motor neuropathy, type II distal hereditary motor neuropathy, type II Enable Javascript to view the expand/ ... Open All Close All Description Distal hereditary motor neuropathy, type II is a progressive disorder that affects ...

  19. Selected methods for dissolved iron (II, III) and dissolved sulfide (-II) determinations in geothermal waters

    USGS Publications Warehouse

    Vivit, D.V.; Jenne, E.A.

    1985-01-01

    Dissolved sulfide (-II) and dissolved iron (II, III) were determined in geothermal well water samples collected at Cerro Prieto, Mexico. Most samples consisted of liquid and gas (two phases) at the instant of collection; and a subset of samples, referred to as ' flashed ' samples, consisted of pressurized steam samples which were allowed to condense. Sulfide was determined by sulfide specific ion electrode; Fe(II) and Fe(III) plus Fe(II) were determined spectrophotometrically. The precision and accuracy of the methods were evaluated for these high-silica waters with replicate analyses, spike recoveries, and an alternate method. Direct current (d.c.) argon plasma emission spectrometry was the alternate method used for Fe(III)-plus-Fe(II) analyses. Mean dissolved iron concentrations ranged from 20.2 to 834 micrograms/L (ug/L) as Fe(II) and 26.8 to 904 ug/L as Fe(III) plus Fe(II). Mean sulfide concentrations ranged from about 0.01 to 5.3 mg/L (S-II) Generally, higher S(-II) values and larger Fe(II)/Fe(III) ratios were found in the two-phase samples. These findings suggest that the ' flashed ' samples are at a less reduced state than the two-phase samples. (Author 's abstract)

  20. Kinetics of homogeneous and surface-catalyzed mercury(II) reduction by iron(II)

    USGS Publications Warehouse

    Amirbahman, Aria; Kent, Douglas B.; Curtis, Gary P.; Marvin-DiPasquale, Mark C.

    2013-01-01

    Production of elemental mercury, Hg(0), via Hg(II) reduction is an important pathway that should be considered when studying Hg fate in environment. We conducted a kinetic study of abiotic homogeneous and surface-catalyzed Hg(0) production by Fe(II) under dark anoxic conditions. Hg(0) production rate, from initial 50 pM Hg(II) concentration, increased with increasing pH (5.5–8.1) and aqueous Fe(II) concentration (0.1–1 mM). The homogeneous rate was best described by the expression, rhom = khom [FeOH+] [Hg(OH)2]; khom = 7.19 × 10+3 L (mol min)−1. Compared to the homogeneous case, goethite (α-FeOOH) and hematite (α-Fe2O3) increased and γ-alumina (γ-Al2O3) decreased the Hg(0) production rate. Heterogeneous Hg(0) production rates were well described by a model incorporating equilibrium Fe(II) adsorption, rate-limited Hg(II) reduction by dissolved and adsorbed Fe(II), and rate-limited Hg(II) adsorption. Equilibrium Fe(II) adsorption was described using a surface complexation model calibrated with previously published experimental data. The Hg(0) production rate was well described by the expression rhet = khet [>SOFe(II)] [Hg(OH)2], where >SOFe(II) is the total adsorbed Fe(II) concentration; khet values were 5.36 × 10+3, 4.69 × 10+3, and 1.08 × 10+2 L (mol min)−1 for hematite, goethite, and γ-alumina, respectively. Hg(0) production coupled to reduction by Fe(II) may be an important process to consider in ecosystem Hg studies.

  1. An uncertain role for Cu(II) in stimulating Mn(II) oxidation by Leptothrix discophora SS-1.

    PubMed

    El Gheriany, Iman A; Bocioaga, Daniela; Hay, Anthony G; Ghiorse, William C; Shuler, Michael L; Lion, Leonard W

    2011-02-01

    In an effort to improve understanding of the role of Cu(II) in bacterial Mn(II) oxidation, a model Mn(II)-oxidizing bacterium, Leptothrix discophora SS-1, was grown in presence of toxic and non-toxic concentrations of Cu(II), Cd(II) and Mn(II). Mn(II)-oxidizing activity increased by 40% when cells were grown in the presence of 0.05 microM of Cu(II) and increased twofold at 0.18 microM Cu(II). Toxic levels of Cd(II) did not stimulate Mn(II) oxidizing activity, indicating that Mn(II) oxidation is not a response to metal toxicity. Stimulation by Cu(II) confirms the specific role of Cu(II) in Mn(II) oxidation. Comparison of transcript levels of the multicopper oxidase mofA gene in the presence and absence of added Cu(II) do not indicate a statistically significant change in mofA transcript levels in cultures supplemented with Cu(II). Thus, the exact role of Cu(II) in Mn(II) oxidation and its affect on mofA gene expression remain uncertain. PMID:21063867

  2. Mucopolysaccharidosis type II, Hunter's syndrome.

    PubMed

    Tylki-Szymańska, Anna

    2014-09-01

    Hunter syndrome is caused by deficiency of the lysososmal enzyme iduronate-2-sulphatase that cleaves O-linked sulphate moieties from dermatan sulphate and heparan sulphate and leads to accumulation of GAGs. The disease is a X-linked condition affecting males and rarely females, clinically divided into severe (2/3) and attenuated types. Children with severe form, diagnosed at 12-36 months, have coarse facial feature, short stature, joint stiffness, short neck, broad chest, large head circumference, watery diarrhea, skeletal changes, progressive and profound mental retardation, retinal degeneration' hearing loss, cardiomyopathy, valvular involvement, with progressive thickening and stiffening of the valve leaflets leading to mitral and aortic regurgitation and stenosis . Recurrent and prolonged rhinitis with persistent nasal discharge are the first symptoms of airway disease that manifests itself as noisy breathing and later sleep apnea. Some patients develop ivory-colored skin lesions on the upper back and sides of the upper arms, pathogenomic of Hunter syndrome. The scalp hair becomes coarse, straight and bristly. Inguinal and umbilical hernias occur caused by the disturbed structure of connective tissue and increased liver and spleen volume. Patients with attenuated form have normal intelligence and a milder phenotype. Physical features diagnosed later are similar but less pronounced but progress to severe disease. Sceening is by quantitative assessment of urinary GAGs excretion. Qualitative assessment of GAG by electrophoresis can distinguish the type of mucopolysaccharidosis. Definitive diagnosis is based on enzyme activity assay in leukocytes, fibroblasts or plasma. Molecular testing is recommended mainly for genetic counseling and carrier detection. Limited experience of Haematopoietic stem cell therapy in MPS II showed progressive neurodegeneration. Recombinant 125 Idursulfase, is indicated for long-term treatment. The response appears to depend on the

  3. Mucopolysaccharidosis type II, Hunter's syndrome.

    PubMed

    Tylki-Szymańska, Anna

    2014-09-01

    Hunter syndrome is caused by deficiency of the lysososmal enzyme iduronate-2-sulphatase that cleaves O-linked sulphate moieties from dermatan sulphate and heparan sulphate and leads to accumulation of GAGs. The disease is a X-linked condition affecting males and rarely females, clinically divided into severe (2/3) and attenuated types. Children with severe form, diagnosed at 12-36 months, have coarse facial feature, short stature, joint stiffness, short neck, broad chest, large head circumference, watery diarrhea, skeletal changes, progressive and profound mental retardation, retinal degeneration' hearing loss, cardiomyopathy, valvular involvement, with progressive thickening and stiffening of the valve leaflets leading to mitral and aortic regurgitation and stenosis . Recurrent and prolonged rhinitis with persistent nasal discharge are the first symptoms of airway disease that manifests itself as noisy breathing and later sleep apnea. Some patients develop ivory-colored skin lesions on the upper back and sides of the upper arms, pathogenomic of Hunter syndrome. The scalp hair becomes coarse, straight and bristly. Inguinal and umbilical hernias occur caused by the disturbed structure of connective tissue and increased liver and spleen volume. Patients with attenuated form have normal intelligence and a milder phenotype. Physical features diagnosed later are similar but less pronounced but progress to severe disease. Sceening is by quantitative assessment of urinary GAGs excretion. Qualitative assessment of GAG by electrophoresis can distinguish the type of mucopolysaccharidosis. Definitive diagnosis is based on enzyme activity assay in leukocytes, fibroblasts or plasma. Molecular testing is recommended mainly for genetic counseling and carrier detection. Limited experience of Haematopoietic stem cell therapy in MPS II showed progressive neurodegeneration. Recombinant 125 Idursulfase, is indicated for long-term treatment. The response appears to depend on the

  4. NSLS-II Transport Line Progress

    SciTech Connect

    Fliller R. P.; Wahl, W.; Anderson, A.; Benish, B.; DeBoer, W.; Ganetis, G.; Heese, R.; Hseuh, H.-C.; Hu, J.-P.; Johanson, M.P.; Kosciuk, B.N.; Padrazo, D.; Roy, K.; Shaftan, T.; Singh, O.; Tuozzolo, J.; Wang, G.

    2012-05-20

    The National Synchrotron Light Source II (NSLS-II) is a state-of-the-art 3-GeV third generation light source currently under construction at Brookhaven National Laboratory. The NSLS-II injection system consists of a 200 MeV linac, a 3-GeV booster synchrotron and associated transfer lines. The first part of the Linac to Booster Transport (LBT) line has been installed for linac commissioning. This part includes all components necessary to commission the NSLS-II linac. The second part of this transport line is undergoing installation. Initial results of hardware commissioning will be discussed. The Booster to Storage Ring (BSR) transport line underwent a design review. The first part of the BSR transport line, consisting of all components necessary to commission the booster will be installed in 2012 for booster commissioning. We report on the final design of the BSR line along with the plan to commission the booster.

  5. Culturally and linguistically responsive teaching: part II.

    PubMed

    Billings, Diane M

    2015-03-01

    This part II of a two-part article about culturally and linguistically responsive teaching provides suggestions for evaluating learners who are culturally and linguistically diverse (CALD) and are often under-represented in nursing education settings.

  6. Zodiac II: Debris Disk Imaging Potential

    NASA Technical Reports Server (NTRS)

    Traub Wesley; Bryden, Geoff; Stapelfeldt, Karl; Chen, Pin; Trauger, John

    2011-01-01

    Zodiac II is a proposed coronagraph on a balloon-borne platform, for the purpose of observing debris disks around nearby stars. Zodiac II will have a 1.2-m diameter telescope mounted in a balloon-borne gondola capable of arcsecond quality pointing, and with the capability to make long-duration (several week) flights. Zodiac II will have a coronagraph able to make images of debris disks, meaning that its scattered light speckles will be at or below an average contrast level of about 10(exp -7) in three narrow (7 percent) bands centered on the V band, and one broad (20%) one at I band. We will discuss the potential science to be done with Zodiac II.

  7. Resistance domain in type II superconductors

    SciTech Connect

    Gurevich, A.V.; Mints, R.G.

    1980-01-05

    We show that traveling domains with a finite resistance can exist in type II superconductors in the presence of a transport current. An experiment in which this effect generates an alternating electric field and current is proposed.

  8. Far Outer Galaxy H II Regions

    NASA Technical Reports Server (NTRS)

    Rudolph, A. L.; deGues, E. J.; Brand, J.; Wouterloot, J. G. A.; Gross, Anthony R. (Technical Monitor)

    1994-01-01

    We have made a multifrequency (6, 3.6, and 2 cm), high-resolution (3"-6"), radio continuum survey of IRAS selected sources from the catalogue of Wouterloot & Brand (1989) to search for and study H II regions in the far outer Galaxy. We identified 31 sources in this catalog with well determined galactocentric distances, and with R approx.. greater than 15 kpc and L(sub FIR) approx.greater than 10(exp 4) solar luminosity, indicating the presence of high-mass star-formation. We have observed 11 of these sources with the Very Large Array (VLA). We observed the sources at 6 and 2 cm using "scaled arrays", making possible a direct and reliable comparison of the data at these two wavelengths for the determination of spectral indices. We detected a total of 12 radio sources, of which 10 have spectral indices consistent with optically-thin free-free emission from H II regions. Combined with previous VLA observations by other investigators, we have data on a total of 15 H II regions at galactocentric distances of 15 to 18.2kpc, among the most remote H II regions found in our Galaxy. The sizes of the H II regions range from approx. less than 0.10 to 2.3 pc. Using the measured fluxes and sizes, we determine the electron densities, emission measures, and excitation parameters of the H II regions, as well as the fluxes of Lyman continuum photons needed to keep the nebulae ionized. The sizes and electron densities are consistent with most of the sources detected in this survey being compact or ultracompact H II regions. Seven of the fifteen H II regions have sizes approx. less than 0.20 pc. Assuming simple pressure-driven expansion of the H II regions, these sizes indicate ages approx. less than 5 x 10(exp 4) yr, or only 1% of the lifetime of an O star, which implies an unlikely overabundance of O stars in the outer Galaxy. Thus, the large number of compact H II regions suggests that the time these regions spend in a compact phase must be much longer than their dynamical

  9. Topoisomerase II Mediates Meiotic Crossover Interference

    PubMed Central

    Zhang, Liangran; Wang, Shunxin; Yin, Shen; Hong, Soogil; Kim, Keun P.; Kleckner, Nancy

    2014-01-01

    Summary Spatial patterning is a ubiquitous feature of biological systems. Meiotic crossovers provide an interesting example, defined by the classical phenomenon of crossover interference. Here, analysis of crossover patterns in budding yeast identifies a molecular pathway for interference. Topoisomerase II (Topo II) plays a central role, thus identifying a new function for this critical molecule. SUMOylation [of TopoII and axis component Red1] and ubiquitin-mediated removal of SUMOylated proteins are also required. These and other findings support the hypothesis that crossover interference involves accumulation, relief and redistribution of mechanical stress along the protein/DNA meshwork of meiotic chromosome axes, with TopoII required to adjust spatial relationships among DNA segments. PMID:25043020

  10. Achondrogenesis type II, abnormalities of extracellular matrix.

    PubMed

    Horton, W A; Machado, M A; Chou, J W; Campbell, D

    1987-09-01

    Immune and lectin histochemical and microchemical methods were employed to study growth cartilage from seven cases of achondrogenesis type II (Langer-Saldino). The normal architecture of the epiphyseal and growth plate cartilage was replaced by a morphologically heterogeneous tissue. Some areas were comprised of vascular canals surrounded by extensive fibrous tissue and enlarged cells that had the appearance and histochemical characteristics of hypertrophic chondrocytes. Other areas contained a mixture of cells ranging from small to the enlarged chondrocytes. The extracellular matrix in the latter areas was more abundant and had characteristics of both precartilage mesenchymal matrix and typical cartilage matrix; it contained types I and II collagen, cartilage proteoglycan, fibronectin, and peanut agglutinin binding glycoconjugate(s). Peptide mapping of cyanogen bromide cartilage collagen peptides revealed the presence of types I and II collagen. These observations could be explained by a defect in the biosynthesis of type II collagen or in chondrocyte differentiation. PMID:3309860

  11. Achondrogenesis II-hypochondrogenesis: variability versus heterogeneity.

    PubMed

    Borochowitz, Z; Ornoy, A; Lachman, R; Rimoin, D L

    1986-06-01

    Recently hypochondrogenesis was described as a form of neonatally lethal dwarfism said to resemble spondyloepiphyseal dysplasia congenita radiographically and achondrogenesis II morphologically. Because of the difficulty in distinguishing radiographically between mild achondrogenesis II and severe hypochondrogenesis, we performed a clinical, radiographic, and morphologic study of 24 cases originally classified as either achondrogenesis II or hypochondrogenesis, in an attempt to distinguish between heterogeneity and clinical variability. Review of the radiographic findings in these cases show a fairly continuous spectrum of bony defects, rather than two distinct radiographic syndromes. Chondro-osseous histology and ultrastructure was similar in all cases regardless of severity and was characterized by hypervascularity and hypercellularity of the cartilage with multiple small, round dilated cysternae of rough endoplasmic reticulum. These findings suggest that hypochondrogenesis and achondrogenesis type II represent a spectrum with marked phenotypic variability. PMID:3717210

  12. SCORPION II persistent surveillance system update

    NASA Astrophysics Data System (ADS)

    Coster, Michael; Hunt, Cassandra

    2011-06-01

    This paper highlights the most recently added features and benefits available in the latest generation of Northrop Grumman SCORPION II persistent surveillance and target recognition systems. By leveraging smaller, lighter, and more power efficient SCORPION II sensor and universal gateway components, with foliage penetrating ad-hoc network communications, persistent field programmable systems that are easier to conceal can be optimized for both image capture and data exfiltration. In addition to the SCORPION II suite of sensor components, a growing list of over sixty different sensor and camera types from a variety of manufacturers have been integrated with the SCORPION Gateway family. In addition to updating several different COP systems, SCORPION and SCORPION II data can be directly processed using a common sensor status graphical user interface (GUI) that allows for viewing and analysis of images and sensor data from hundreds of SCORPION system gateways on single or multiple displays.

  13. PEP-II Status and Outlook

    SciTech Connect

    Wienands, H.U.; Biagini, M.E.; Decker, F.J.; Donald, M.H.; Ecklund, S.; Fisher, A.; Holtzapple, R.L.; Iverson, R.H.; Krejcik, P.; Kulikov, A.V.; Meyer, T.; Nelson, J.; Novokhatski, A.; Reichel, I.; Sullivan, M.; Seeman, J.T.; Turner, J.; Steier, C.; Zisman, M.S.; /LBL, Berkeley

    2012-04-24

    PEP-II/BABAR are presently in their second physics run. With machine and detector performance and reliability at an all-time high, almost 51 fb{sup -1} have been integrated by BABAR up to mid-October 2001. PEP-II luminosity has reached 4.4 x 10{sup 33} cm{sup -2} s{sup -1} and our highest monthly delivered luminosity has been above 6 pb{sup -1}, exceeding the performance parameters given in the PEP-II CDR by almost 50%. The increase compared to the first run in 2000 has been achieved by a combination of beam-current increase and beam-size decrease. In this paper we will summarize the PEP-II performance and the present limitations as well as our plans to further increase machine performance.

  14. Database for mobile group II introns.

    PubMed

    Dai, Lixin; Toor, Navtej; Olson, Robert; Keeping, Andrew; Zimmerly, Steven

    2003-01-01

    Group II introns are self-splicing RNAs and retroelements found in bacteria and lower eukaryotic organelles. During the past several years, they have been uncovered in surprising numbers in bacteria due to the genome sequencing projects; however, most of the newly sequenced introns are not correctly identified. We have initiated an ongoing web site database for mobile group II introns in order to provide correct information on the introns, particularly in bacteria. Information in the web site includes: (1) introductory information on group II introns; (2) detailed information on subfamilies of intron RNA structures and intron-encoded proteins; (3) a listing of identified introns with correct boundaries, RNA secondary structures and other detailed information; and (4) phylogenetic and evolutionary information. The comparative data should facilitate study of the function, spread and evolution of group II introns. The database can be accessed at http://www.fp.ucalgary.ca/group2introns/.

  15. Removal of Pb(II), Cd(II), Cu(II), and Zn(II) by hematite nanoparticles: effect of sorbent concentration, pH, temperature, and exhaustion.

    PubMed

    Shipley, Heather J; Engates, Karen E; Grover, Valerie A

    2013-03-01

    Nanoparticles offer the potential to improve environmental treatment technologies due to their unique properties. Adsorption of metal ions (Pb(II), Cd(II), Cu(II), Zn(II)) to nanohematite was examined as a function of sorbent concentration, pH, temperature, and exhaustion. Adsorption experiments were conducted with 0.05, 0.1, and 0.5 g/L nanoparticles in a pH 8 solution and in spiked San Antonio tap water. The adsorption data showed the ability of nanohematite to remove Pb, Cd, Cu, and Zn species from solution with adsorption increasing as the nanoparticle concentration increased. At 0.5 g/L nanohematite, 100 % Pb species adsorbed, 94 % Cd species adsorbed, 89 % Cu species adsorbed and 100 % Zn species adsorbed. Adsorption kinetics for all metals tested was described by a pseudo second-order rate equation with lead having the fastest rate of adsorption. The effect of temperature on adsorption showed that Pb(II), Cu(II), and Cd(II) underwent an endothermic reaction, while Zn(II) underwent an exothermic reaction. The nanoparticles were able to simultaneously remove multiple metals species (Zn, Cd, Pb, and Cu) from both a pH 8 solution and spiked San Antonio tap water. Exhaustion experiments showed that at pH 8, exhaustion did not occur for the nanoparticles but adsorption does decrease for Cd, Cu, and Zn species but not Pb species. The strong adsorption coupled with the ability to simultaneously remove multiple metal ions offers a potential remediation method for the removal of metals from water.

  16. Antenatal diagnosis of achondrogenesis type II.

    PubMed

    Kodandapani, S; Ramkumar, V

    2009-01-01

    Achondrogenesis is a lethal congenital chondrodystrophy characterized by extreme micromelia, small thorax and polyhydramnios. We describe a case of achondrogenesis type II (Langer-Saldino achondrogenesis). Prenatal ultrasonography at 22-weeks gestation revealed a fetus with large head, short neck and chest, prominent abdomen and short limbs. Pregnancy was terminated. Radiologic examination of neonate revealed features of achondrogenesis type II. Routine ultrasound screening made early detection and timely management possible. PMID:20387359

  17. EXODUS II: A finite element data model

    SciTech Connect

    Schoof, L.A.; Yarberry, V.R.

    1994-09-01

    EXODUS II is a model developed to store and retrieve data for finite element analyses. It is used for preprocessing (problem definition), postprocessing (results visualization), as well as code to code data transfer. An EXODUS II data file is a random access, machine independent, binary file that is written and read via C, C++, or Fortran library routines which comprise the Application Programming Interface (API).

  18. The Ssart of Run II at CDF

    SciTech Connect

    Marco Rescigno

    2002-10-29

    After a hiatus of almost 6 years and an extensive upgrade, Tevatron, the world largest proton-antiproton collider, has resumed the operation for the so called RUN II. In this paper we give a brief overview of the many new features of the Tevatron complex and of the upgraded CDF experiment, and show the presently achieved detector performances as well as highlights of the RUN II physics program in the beauty and electroweak sector.

  19. NSLS-II Radio Frequency Systems

    SciTech Connect

    Rose J.; Gao F.; Goel, A.; Holub, B.; Kulpin, J.; Marques, C.; Yeddulla, M.

    2015-05-03

    The National Synchrotron Light Source II is a 3 GeV X-ray user facility commissioned in 2014. The NSLS-II RF system consists of the master oscillator, digital low level RF controllers, linac, booster and storage ring RF sub-systems, as well as a supporting cryogenic system. Here we will report on RF commissioning and early operation experience of the system.

  20. NSLS-II Beam Diagnostics Overview

    SciTech Connect

    Singh,O.; Alforque, R.; Bacha, B.; Blednykh, A.; Cameron, P.; Cheng, W.; Dalesio, L. B.; Della Penna, A. J.; doom, L.; Fliller, R. P.; Ganetis, G.; Heese, R.; Hseuh, H-C.; Johnson, E. D.; Kosciuk, b. N.; Kramer, S. L.; Krinsky, S.; Mead, J.; Ozaki, S.; Padrazo, D.; Pinayev, I.; Ravindranath, R. V.; Rose, J.; Shaftan, T.; Sharma, S.; Skaritka, J.; Tanabe, T.; Tian, Y.; Willeke, F. J.; Yu, L-H.

    2009-05-04

    A new 3rd generation light source (NSLS-II) is in the early stages of construction at Brookhaven National Laboratory. The NSLS-II facility will provide ultra high brightness and flux with exceptional beam stability. It presents several challenges for diagnostics and instrumentation, related to the extremely small emittance. In this paper, we present an overview of all planned instrumentation systems, results from research and development activities; and then focus on other challenging aspects.

  1. Performance of dipole magnets in helium II

    SciTech Connect

    Althaus, R.; Caspi, S.; Gilbert, W.S.; Hassenzahl, W.; Meuser, R.; Rechen, J.; Taylor, C.; Warren, R.

    1981-03-01

    Data from tests in He II of four 1-meter-long magnets are presented. The maximum quench current is increased up to 30 percent, compared with tests in He I. Data from calorimetric measurements of heat generated during cyclic operation are presented. Quenches were induced by heaters placed near the conductor, and the energy required to induce quenches in He II and in He I are compared.

  2. Synthesis and characterization of hydroxyapatite nanoparticles impregnated on apple pomace to enhanced adsorption of Pb(II), Cd(II), and Ni(II) ions from aqueous solution.

    PubMed

    Chand, Piar; Pakade, Yogesh B

    2015-07-01

    Hydroxyapatite nanoparticles were synthesized, characterized, and impregnated onto apple pomace surface (HANP@AP) for efficient removal of Pb(II), Cd(II), and Ni(II) ions from water. HANP@AP was characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), transmission electron microscope (TEM), X-ray diffraction (XRD), and surface area analysis. Batch sorption studies were carried out to investigate the influence of different parameters as amount of dose (g), pH, time (min), and initial concentration (mg L(-1)) on adsorption process. Experimental kinetic data followed pseudo-second-order model and equilibrium data well fitted to Langmuir adsorption model with maximum adsorption capacities of 303, 250, and 100 mg g(-1) for Pb(II), Cd(II), and Ni(II) ions, respectively. Competitive adsorption of Pb(II), Cd(II), and Ni(II) ions in presences of each other was studied to evaluate the removal efficiency of HANP@AP against multi metal-loaded water. HANP@AP was successfully applied to real industrial wastewater with 100 % removal of all three metal ions even at high concentration. HANP@AP could be recycled for four, four, and three cycles in case of Pb(II), Cd(II) and Ni(II), respectively. The study showed that HANP@AP is fast, cost effective, and environmental friendly adsorbent for removal of Pb(II), Cd(II), and Ni(II) ions from real industrial wastewater.

  3. Pb(II) and Cd(II) removal from aqueous solutions by olive cake.

    PubMed

    Doyurum, Sabriye; Celik, Ali

    2006-11-01

    The removal of heavy metals from wastewater using olive cake as an adsorbent was investigated. The effect of the contact time, pH, temperature, and concentration of adsorbate on adsorption performance of olive cake for Pb(II) and Cd(II) ions were examined by batch method. Adsorption of Pb(II) and Cd(II) in aqueous solution onto olive cake was studied in single component. After establishing the optimum conditions, elution of these ions from the adsorbent surface was also examined. The optimum sorption conditions were determined for two elements. Maximum desorption of the Pb(II) and Cd(II) ions were found to be 95.92 and 53.97% by 0.5M HNO(3) and 0.2M HCl, respectively. The morphological analysis of the olive cake was performed by the scanning electron microscopy (SEM). PMID:16806680

  4. Preferred crystallographic orientation in the ice I ← II transformation and the flow of ice II

    USGS Publications Warehouse

    Bennett, K.; Wenk, H.-R.; Durham, W.B.; Stern, L.A.; Kirby, S.H.

    1997-01-01

    The preferred crystallographic orientation developed during the ice I ← II transformation and during the plastic flow of ice II was measured in polycrystalline deuterium oxide (D2O) specimens using low-temperature neutron diffraction. Samples partially transformed from ice I to II under a non-hydrostatic stress developed a preferred crystallographic orientation in the ice II. Samples of pure ice II transformed from ice I under a hydrostatic stress and then when compressed axially, developed a strong preferred orientation of compression axes parallel to (1010). A match to the observed preferred orientation using the viscoplastic self-consistent theory was obtained only when (1010) [0001] was taken as the predominant slip system in ice II.

  5. PIVKA-II-producing advanced gastric cancer.

    PubMed

    Takano, Shigetsugu; Honda, Ichiro; Watanabe, Satoshi; Soda, Hiroaki; Nagata, Matsuo; Hoshino, Isamu; Takenouchi, Toshinao; Miyazaki, Masaru

    2004-08-01

    We describe the case of a 68-year-old man with primary advanced adenocarcinoma of the stomach, who displayed extremely high plasma levels of protein induced by vitamin K antagonist (PIVKA)-II (15 600 mAU/ml) and normal levels of alphafetoprotein (AFP) (4 ng/ml). Ultrasonography and dynamic computed tomography ruled out hepatocellular carcinoma (HCC) or liver metastasis. After preoperative chemotherapy, pancreatico-spleno total gastrectomy with D2 lymphadenectomy was performed. Postoperatively, plasma levels of PIVKA-II returned to within the normal range (29 mAU/ml). Microscopic examination revealed stomach adenocarcinoma showing various histological types, such as moderately to poorly differentiated mucinous adenocarcinoma, but hepatoid differentiation of gastric adenocarcinoma was not detected. Localization of PIVKA-II and AFP within tumor cells was demonstrated by immunohistochemical staining using monoclonal antibodies. These results indicate that tumor cells from gastric cancer may produce PIVKA-II. Some cases of PIVKA-II- and AFP-producing advanced gastric cancer with liver metastasis have been reported, but this is the first report of gastric cancer without liver metastasis producing PIVKA-II alone.

  6. Group II Introns and Their Protein Collaborators

    NASA Astrophysics Data System (ADS)

    Solem, Amanda; Zingler, Nora; Pyle, Anna Marie; Li-Pook-Than, Jennifer

    Group II introns are an abundant class of autocatalytic introns that excise themselves from precursor mRNAs. Although group II introns are catalytic RNAs, they require the assistance of proteins for efficient splicing in vivo. Proteins that facilitate splicing of organellar group II introns fall into two main categories: intron-encoded maturases and host-encoded proteins. This chapter will focus on the host proteins that group II introns recruited to ensure their function. It will discuss the great diversity of these proteins, define common features, and describe different strategies employed to achieve specificity. Special emphasis will be placed on DEAD-box ATPases, currently the best studied example of host-encoded proteins with a role in group II intron splicing. Since the exact mechanisms by which splicing is facilitated is not known for any of the host proteins, general mechanistic strategies for protein-mediated RNA folding are described and assessed for their potential role in group II intron splicing.

  7. Calcitonin metabolism in senile (type II) osteoporosis.

    PubMed

    Reginster, J Y; Deroisy, R; Bruwier, M; Franchimont, P

    1992-05-01

    The exact role of calcitonin (CT) in the pathogenesis of senile (Type II) osteoporosis remains unknown. Whole plasma calcitonin (iCT) and extracted monomeric calcitonin (eCT) basal levels, metabolic clearance rate (MCR) and production rate (PR) of iCT and eCT were measured in 41 postmenopausal women, including 14 hip fractures (OP II) and 27 healthy controls. No significant difference appeared for basal iCT levels between OP II (mean +/- SEM: 41.9 +/- 3.4 pg/ml) and controls (mean +/- SEM: 46.2 +/- 5 pg/ml). eCT basal levels were similar in OP II (mean +/- SEM: 5.42 +/- 0.5 pg/ml) and in controls (mean +/- SEM: 7.3 +/- 0.7 pg/ml). MCR were similar in the two groups. iCT PR were similar in OP II (mean +/- SEM: 17.2 +/- 1.5 micrograms/24 h) and controls (mean +/- SEM: 18.6 +/- 1.1 micrograms/24 h). No difference appeared between eCT PR in OP II (mean +/- SEM: 2.3 +/- 0.2 micrograms/24 h) and controls (mean +/- SEM: 3.2 +/- 0.3 pg/ml). From these data, no evidence appears that calcitonin might be one of the determinant factors in the pathogenesis of senile osteoporosis.

  8. AUGO II: A Comprehensive Subauroral Zone Observatory

    NASA Astrophysics Data System (ADS)

    Schofield, I. S.; Connors, M. G.

    2012-12-01

    Athabasca University Geophysical Observatory II (AUGO II) is a comprehensive subauroral zone observatory designed for routine automated optical and magnetic observation of the aurora. Becoming operational in February 2012, AUGO II has six temperature/humidity controlled observation rooms, each equipped with a 1.5 meter diameter acrylic dome custom fabricated for wide spectral transparency. AUGO II is located approximately 25 km southwest of the town of Athabasca, in Alberta, Canada, on the southern edge of the auroral zone (Geodetic coordinates: latitude 54 36' 10", longitude 113 38' 40" west. CGM coordinates: latitude 61.7, longitude 306.8, L-value 4.5). AUGO II is sufficiently isolated from urban development that skies are dark enough during winter months to allow optical studies of faint phenomena, such as H-beta studies of proton precipitation aurora, currently underway. The observatory's modest residence can accommodate six persons, allowing groups to live and work with their instruments for the duration of their research campaign without leaving the site. AUGO II's inaugural guest research campaign was reported successful, and resulted in a permanent VLF/LF radio experiment being deployed at the observatory's expansive site. We are hopeful more research groups will take advantage of this unique facility and help realize its full potential.

  9. Coronal type II bursts and interplanetary type II bursts: Distinct shock drivers

    NASA Astrophysics Data System (ADS)

    Suryanarayana, G. S.

    2012-02-01

    We study solar radio type II bursts combining with Wind/WAVES type II bursts and coronal mass ejections (CMEs). The aim of the present work is to investigate the effectiveness of shocks to cause type II bursts in the solar corona and the interplanetary space. We consider the following findings. The distribution of the cessation heights of type II emission is confined to a rather narrow range of height than the distribution of the heights of start frequencies. This is suggestive of the presence of a gradient for the Alfvén speed from the heliocentric height of ˜1.4 solar radii. The range of the kinetic energy of CMEs associated with coronal type II emission taken together with the suggested computation method and the Alfvén speed gradient, indicates the limit to the height up to which type II emission could be expected. This height is ˜2 solar radii from the center of the Sun. Further, the large time gap between the cessation time and heights of coronal type II emission and the commencement time and heights of most of the IP type II bursts do not account for the difference between the two heights and the average shock speed. Also, there is clear difference in the magnitude of the kinetic energies and the distinct characteristics of the CMEs associated with coronal and IP type II bursts. Hence, we suggest that in most instances the coronal type II bursts and IP type II bursts occur due to distinct shocks. We also address the question of the origin of type II bursts and discuss the possible explanation of observed results.

  10. 40 CFR Table 1 to Subpart II of... - General Provisions of Applicability to Subpart II

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Reference Applies to subpart II Comment 63.1(a)(1)-(3) Yes. 63.1(a)(4) Yes Subpart II clarifies the applicability of each paragraph in subpart A to sources subject to subpart II. 63.1(a)(5)-(7) Yes 63.1(a)(8) No Discusses State programs. 63.1(a)(9)-(14) Yes 63.1(b)(1) Yes § 63.781 specifies applicability in more...

  11. Competitive sorption of Pb(II), Cu(II) and Ni(II) on carbonaceous nanofibers: A spectroscopic and modeling approach.

    PubMed

    Ding, Congcong; Cheng, Wencai; Wang, Xiangxue; Wu, Zhen-Yu; Sun, Yubing; Chen, Changlun; Wang, Xiangke; Yu, Shu-Hong

    2016-08-01

    The competitive sorption of Pb(II), Cu(II) and Ni(II) on the uniform carbonaceous nanofibers (CNFs) was investigated in binary/ternary-metal systems. The pH-dependent sorption of Pb(II), Cu(II) and Ni(II) on CNFs was independent of ionic strength, indicating that inner-sphere surface complexation dominated sorption Pb(II), Cu(II) and Ni(II) on CNFs. The maximum sorption capacities of Pb(II), Cu(II) and Ni(II) on CNFs in single-metal systems at a pH 5.5±0.2 and 25±1°C were 3.84 (795.65mg/g), 3.21 (204.00mg/g) and 2.67 (156.70mg/g)mmol/g, respectively. In equimolar binary/ternary-metal systems, Pb(II) exhibited greater inhibition of the sorption of Cu(II) and Ni(II), demonstrating the stronger affinity of CNFs for Pb(II). The competitive sorption of heavy metals in ternary-metal systems was predicted quite well by surface complexation modeling derived from single-metal data. According to FTIR, XPS and EXAFS analyses, Pb(II), Cu(II) and Ni(II) were specifically adsorbed on CNFs via covalent bonding. These observations should provide an essential start in simultaneous removal of multiple heavy metals from aquatic environments by CNFs, and open the doorways for the application of CNFs. PMID:27108273

  12. Circulating angiotensin II deteriorates left ventricular function with sympathoexcitation via brain angiotensin II receptor

    PubMed Central

    Shinohara, Keisuke; Kishi, Takuya; Hirooka, Yoshitaka; Sunagawa, Kenji

    2015-01-01

    Sympathoexcitation contributes to the progression of heart failure. Activation of brain angiotensin II type 1 receptors (AT1R) causes central sympathoexcitation. Thus, we assessed the hypothesis that the increase in circulating angiotensin II comparable to that reported in heart failure model affects cardiac function through the central sympathoexcitation via activating AT1R in the brain. In Sprague-Dawley rats, the subcutaneous infusion of angiotensin II for 14 days increased the circulating angiotensin II level comparable to that reported in heart failure model rats after myocardial infarction. In comparison with the control, angiotensin II infusion increased 24 hours urinary norepinephrine excretion, and systolic blood pressure. Angiotensin II infusion hypertrophied left ventricular (LV) without changing chamber dimensions while increased end-diastolic pressure. The LV pressure–volume relationship indicated that angiotensin II did not impact on the end-systolic elastance, whereas significantly increased end-diastolic elastance. Chronic intracerebroventricular infusion of AT1R blocker, losartan, attenuated these angiotensin II-induced changes. In conclusion, circulating angiotensin II in heart failure is capable of inducing sympathoexcitation via in part AT1R in the brain, subsequently leading to LV diastolic dysfunction. PMID:26290529

  13. Synthesis, spectroscopic studies and crystal structure of the Schiff base ligand L derived from condensation of 2-thiophenecarboxaldehyde and 3,3'-diaminobenzidine and its complexes with Co(II), Ni(II), Cu(II), Cd(II) and Hg(II): Comparative DNA binding studies of L and its Co(II), Ni(II) and Cu(II) complexes

    NASA Astrophysics Data System (ADS)

    Shakir, Mohammad; Abbasi, Ambreen; Azam, Mohammad; Khan, Asad U.

    2011-09-01

    The Schiff base ligand, N,N'-bis-(2-thiophenecarboxaldimine)-3,3'-diaminobenzidine (L) obtained from condensation of 2-thiophenecarboxaldehyde and 3,3'-diaminobenzidine, was used to synthesize the complexes of type, [M 2L 2]Cl 4 [M = Co(II), Ni(II), Cu(II), Cd(II) and Hg(II)]. The newly synthesized ligand (L) was characterized on the basis of the results of elemental analysis, FT-IR, 1H NMR, 13C NMR, mass spectroscopic studies and single crystal X-ray crystallography. The characteristic resonance signals in 1H NMR and 13C NMR spectra indicated the presence of azomethine group as a result of condensation reaction. The stoichiometry, bonding and stereochemistries of complexes were ascertained on the basis of results of elemental analysis, magnetic susceptibility measurements, molar conductance and spectroscopic studies viz., FT-IR, 1H and 13C NMR, UV-vis and EPR. EPR, UV-vis and magnetic moment data revealed an octahedral geometry for complexes with distortion in Cu(II) complex and conductivity data show 1:2 electrolytic nature of complexes. Absoption and fluorescence spectroscopic studies supported that Schiff base ligand L and its Co(II), Ni(II) and Cu(II) complexes exhibited significant binding to calf thymus DNA. The complexes exhibited higher affinity to calf thymus DNA than the free Schiff base ligand L.

  14. STELLAR POPULATIONS AND THE STAR FORMATION HISTORIES OF LOW SURFACE BRIGHTNESS GALAXIES. II. H II REGIONS

    SciTech Connect

    Schombert, James; McGaugh, Stacy; Maciel, Tamela E-mail: stacy.mcgaugh@case.edu

    2013-08-01

    The luminosities, colors, and H{alpha} emission for 429 H II regions in 54 low surface brightness (LSB) galaxies are presented. While the number of H II regions per galaxy is lower in LSB galaxies compared to star-forming irregulars and spirals, there is no indication that the size or luminosity function of H II regions differs from other galaxy types. The lower number of H II regions per galaxy is consistent with their lower total star formation rates. The fraction of the total L{sub H{alpha}} contributed by H II regions varies from 10% to 90% in LSB galaxies (the rest of the H{alpha} emission being associated with a diffuse component) with no correlation with galaxy stellar or gas mass. Bright H II regions have bluer colors, similar to the trend in spirals; their number and luminosities are consistent with the hypothesis that they are produced by the same H II luminosity function as spirals. Comparison with stellar population models indicates that the brightest H II regions in LSB galaxies range in cluster mass from a few 10{sup 3} M{sub Sun} (e.g., {rho} Oph) to globular-cluster-sized systems (e.g., 30 Dor) and that their ages are consistent with clusters from 2 to 15 Myr old. The faintest H II regions are comparable to those in the LMC powered by a single O or B star. Thus, star formation in LSB galaxies covers the full range of stellar cluster mass.

  15. Cu(II) and Zn(II) adsorption capacity of three different clay liner materials.

    PubMed

    Musso, T B; Parolo, M E; Pettinari, G; Francisca, F M

    2014-12-15

    Sorption of Cu(II) and Zn(II) on three natural clays meeting the international requirements for use as liners was evaluated by means of batch tests. The purpose of this research was to determine the retention capacities of the clays for metal cations commonly present in urban solid waste leachates. The pH and ionic strength conditions were set at values frequently found in real leachates. The changes observed in the XRD patterns and FTIR spectra upon adsorption can be considered an evidence of clay-metal electrostatic interaction. The Langmuir model was found to best describe the sorption processes, offering maximum sorption capacities from 8.16 to 56.89 mg/g for Cu(II) and from 49.59 to 103.83 mg/g for Zn(II). All samples remove more Zn(II) than Cu(II), which may be related to the different geometry of the hydrated Cu(II) cation. The total amount of metal sorption was strongly influenced by the total specific surface area, the presence of carbonates and the smectite content of the clays. In addition to their known quality as physical barriers, the adsorbed amounts obtained indicate the suitability of the tested clays to contribute to the retardation of Cu(II) and Zn(II) transport through clay liners.

  16. Phosphate effects on copper(II) and lead(II) sorption to ferrihydrite

    NASA Astrophysics Data System (ADS)

    Tiberg, Charlotta; Sjöstedt, Carin; Persson, Ingmar; Gustafsson, Jon Petter

    2013-11-01

    Transport of lead(II) and copper(II) ions in soil is affected by the soil phosphorus status. Part of the explanation may be that phosphate increases the adsorption of copper(II) and lead(II) to iron (hydr)oxides in soil, but the details of these interactions are poorly known. Knowledge about such mechanisms is important, for example, in risk assessments of contaminated sites and development of remediation methods. We used a combination of batch experiments, extended X-ray absorption fine structure (EXAFS) spectroscopy and surface complexation modeling with the three-plane CD-MUSIC model to study the effect of phosphate on sorption of copper(II) and lead(II) to ferrihydrite. The aim was to identify the surface complexes formed and to derive constants for the surface complexation reactions. In the batch experiments phosphate greatly enhanced the adsorption of copper(II) and lead(II) to ferrihydrite at pH < 6. The largest effects were seen for lead(II).

  17. Angiotensin II: role in skeletal muscle atrophy.

    PubMed

    Cabello-Verrugio, Claudio; Córdova, Gonzalo; Salas, José Diego

    2012-09-01

    Skeletal muscle, the main protein reservoir in the body, is a tissue that exhibits high plasticity when exposed to changes. Muscle proteins can be mobilized into free amino acids when skeletal muscle wasting occurs, a process called skeletal muscle atrophy. This wasting is an important systemic or local manifestation under disuse conditions (e.g., bed rest or immobilization), in starvation, in older adults, and in several diseases. The molecular mechanisms involved in muscle wasting imply the activation of specific signaling pathways which ultimately manage muscle responses to modulate biological events such as increases in protein catabolism, oxidative stress, and cell death by apoptosis. Many factors have been involved in the generation and maintenance of atrophy in skeletal muscle, among them angiotensin II (Ang-II), the main peptide of renin-angiotensin system (RAS). Together with Ang-II, the angiotensin-converting enzyme (ACE) and the Ang-II receptor type 1 (AT-1 receptor) are expressed in skeletal muscle, forming an important local axis that can regulate its function. In many of the conditions that lead to muscle wasting, there is an impairment of RAS in a global or local fashion. At this point, there are several pieces of evidence that suggest the participation of Ang-II, ACE, and AT-1 receptor in the generation of skeletal muscle atrophy. Interestingly, the Ang-II participation in muscle atrophy is strongly ligated to the regulation of hypertrophic activity of factors such as insulin-like growth factor 1 (IGF-1). In this article, we reviewed the current state of Ang-II and RAS function on skeletal muscle wasting and its possible use as a therapeutic target to improve skeletal muscle function under atrophic conditions.

  18. Sloan Digital Sky Survey II (SDSS-II), Data Release 7, including the Legacy Survey

    DOE Data Explorer

    The Sloan Digital Sky Survey (SDSS) is a series of three interlocking imaging and spectroscopic surveys, carried out over an eight-year period with a dedicated 2.5m telescope located at Apache Point Observatory in Southern New Mexico. The seventh data release (DR7) from the SDSS represents a completion of the overall, original project, though SDSS-III began in 2008 and will build upon the knowledge gained already. The SDSS Legacy Survey provided a uniform, well-calibrated map of more than 7,500 square degrees of the North Galactic Cap, and three stripes in the South Galactic Cap totaling 740 square degrees. The central stripe in the South Galactic Gap, Stripe 82, was scanned multiple times to enable a deep co-addition of the data and to enable discovery of variable objects. Legacy data supported studies ranging from asteroids and nearby stars to the large-scale structure of the universe. All of the imaging data have been processed to yield calibrated astrometric and photometric parameters and classifications. These parameters are available in one or more tables in a database accessible via the Catalog Archive Server (CAS) at http://cas.sdss.org/astro. [taken and edited from the Legacy page at http://www.sdss.org/legacy/index.html] All three surveys summarized are: 1) Legacy: an imaging survey in five bands over a contiguous 7646 deg2 high-latitude elliptical region in the Northern Galactic Cap, plus an additional 750 deg2 in the Southern Galactic Cap, together with spectroscopy of complete samples of galaxies and quasars covering about 8200 square degrees. The total imaging area in the Legacy survey is 8423 square degrees; 2) SEGUE: (Sloan Extension for Galactic Understanding and Exploration): additional imaging of 3240 deg2 of sky at lower Galactic latitudes, together with spectroscopy of 240,000 stars towards 200 sight lines covering 1400 square degrees (spread throughout the Legacy and SEGUE imaging footprints), to study the structure of the Milky Way; 3

  19. Spectroscopic evaluation of Co(II), Ni(II) and Cu(II) complexes derived from thiosemicarbazone and semicarbazone

    NASA Astrophysics Data System (ADS)

    Chandra, Sulekh; Kumar, Anil

    2007-12-01

    Co(II), Ni(II) and Cu(II) complexes were synthesized with thiosemicarbazone (L 1) and semicarbazone (L 2) derived from 2-acetyl furan. These complexes were characterized by elemental analysis, molar conductance, magnetic moment, mass, IR, electronic and EPR spectral studies. The molar conductance measurement of the complexes in DMSO corresponds to non-electrolytic nature. All the complexes are of high-spin type. On the basis of different spectral studies six coordinated geometry may be assigned for all the complexes except Co(L) 2(SO 4) and Cu(L) 2(SO 4) [where L = L 1 and L 2] which are of five coordinated square pyramidal geometry.

  20. Statistics of equivalent width data and new oscillator strengths for Si II, Fe II, and Mn II. [in interstellar medium

    NASA Technical Reports Server (NTRS)

    Van Buren, Dave

    1986-01-01

    Equivalent width data from Copernicus and IUE appear to have an exponential, rather than a Gaussian distribution of errors. This is probably because there is one dominant source of error: the assignment of the background continuum shape. The maximum likelihood method of parameter estimation is presented for the case of exponential statistics, in enough generality for application to many problems. The method is applied to global fitting of Si II, Fe II, and Mn II oscillator strengths and interstellar gas parameters along many lines of sight. The new values agree in general with previous determinations but are usually much more tightly constrained. Finally, it is shown that care must be taken in deriving acceptable regions of parameter space because the probability contours are not generally ellipses whose axes are parallel to the coordinate axes.

  1. Heterotrimetallic Ru(II)/Pd(II)/Ru(II) complexes: synthesis, crystalstructure, spectral characterization, DFT calculation and antimicrobial study.

    PubMed

    Al-Noaimi, Mousa; Nafady, Ayman; Warad, Ismail; Alshwafy, Rwaida; Husein, Ahmad; Talib, Wamidh H; Hadda, Taibi Ben

    2014-03-25

    New ruthenium(II) mononuclear complexes of the type [RuCl2(PPh3)2(η(2)-triamine)] (2) [RuCl(PPh3)2(η(3)-triamine)]Cl (5) (triemine=N(1)-(2-aminoethyl)-1,2-ethanediamine) have been synthesized by reacting [RuCl2(PPh3)3] (1) with one mole equivalent of N(1)-(2-aminoethyl)-1,2-ethanediamine in dichloromethane. Reaction of (2) with half-equivalent of (PhCN)2PdCl2 or Pd(OAc)2 in dichloromethane as a solvent afforded two novel heterotrimetallic Ru(II)-Pd(II)-Ru(II) complexes, [Ru(II)Cl2(PPh3)2(triamine)]2[Pd(II)X2](X=Cl, OAc) (3 and 4), bearing bioactive ligand. The progress of the undertaken reactions was monitored by (31)P{1H} NMR and FTIR. Crystal structure of complex 2 was confirmed by X-ray diffraction. The absorption spectrum of 2 in dichloromethane was modeled by time-dependent density functional theory (TD-DFT). The in vitro antimicrobial studies of complex 2-5 against an array of microorganisms (bacteria and fungi) were conducted. Complexes 3 and 4 exhibit high dual antibacterial and antifungal activity inhibiting microorganisms possibly via hydrolytic pathway which further evidenced by electrochemical analyses. The complexes 3 and 4 show a high inhibitory activity at 200 μg/ml concentration, suggesting that complexes 3 and 4 are two efficient catalytic inhibitor of microorganisms and further, they should be tested against cancer strains.

  2. 40 CFR Appendix II to Subpart E of... - Sampling Tables

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Sampling Tables II Appendix II to Subpart E of Part 205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE..., Subpt. E, App. II Appendix II to Subpart E of Part 205—Sampling Tables Table 1—Model Year...

  3. 40 CFR Appendix II to Subpart E of... - Sampling Tables

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Sampling Tables II Appendix II to Subpart E of Part 205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE..., Subpt. E, App. II Appendix II to Subpart E of Part 205—Sampling Tables Table 1—Model Year...

  4. 10 CFR Appendix II to Part 504 - Fuel Price Computation

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Fuel Price Computation II Appendix II to Part 504 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS EXISTING POWERPLANTS Pt. 504, App. II Appendix II to Part... effects of future real price increases for each fuel. The delivered price of an alternate fuel used...

  5. 10 CFR Appendix II to Part 504 - Fuel Price Computation

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Fuel Price Computation II Appendix II to Part 504 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS EXISTING POWERPLANTS Pt. 504, App. II Appendix II to Part... effects of future real price increases for each fuel. The delivered price of an alternate fuel used...

  6. 10 CFR Appendix II to Part 504 - Fuel Price Computation

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Fuel Price Computation II Appendix II to Part 504 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS EXISTING POWERPLANTS Pt. 504, App. II Appendix II to Part... effects of future real price increases for each fuel. The delivered price of an alternate fuel used...

  7. 10 CFR Appendix II to Part 504 - Fuel Price Computation

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Fuel Price Computation II Appendix II to Part 504 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS EXISTING POWERPLANTS Pt. 504, App. II Appendix II to Part... effects of future real price increases for each fuel. The delivered price of an alternate fuel used...

  8. 10 CFR Appendix II to Part 504 - Fuel Price Computation

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Fuel Price Computation II Appendix II to Part 504 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS EXISTING POWERPLANTS Pt. 504, App. II Appendix II to Part... effects of future real price increases for each fuel. The delivered price of an alternate fuel used...

  9. 49 CFR 238.317 - Class II brake test.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Class II brake test. 238.317 Section 238.317... Requirements for Tier I Passenger Equipment § 238.317 Class II brake test. (a) A Class II brake test shall be.... In these circumstances, a Class II brake test shall be performed prior to the train's departure...

  10. 49 CFR 238.317 - Class II brake test.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Class II brake test. 238.317 Section 238.317... Requirements for Tier I Passenger Equipment § 238.317 Class II brake test. (a) A Class II brake test shall be.... In these circumstances, a Class II brake test shall be performed prior to the train's departure...

  11. 49 CFR 238.317 - Class II brake test.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Class II brake test. 238.317 Section 238.317... Requirements for Tier I Passenger Equipment § 238.317 Class II brake test. (a) A Class II brake test shall be.... In these circumstances, a Class II brake test shall be performed prior to the train's departure...

  12. THE ARECIBO H II REGION DISCOVERY SURVEY

    SciTech Connect

    Bania, T. M.; Anderson, L. D.; Balser, Dana S.

    2012-11-10

    We report the detection of radio recombination line (RRL) emission using the Arecibo Observatory at X band (9 GHz, 3 cm) from 37 previously unknown H II regions in the Galactic zone 66 Degree-Sign {>=} l {>=} 31 Degree-Sign and | b | {<=} 1 Degree-Sign . This Arecibo H II Region Discovery Survey (Arecibo HRDS) is a continuation of the Green Bank Telescope (GBT) HRDS. The targets for the Arecibo HRDS have spatially coincident 24 {mu}m and 20 cm emission of a similar angular morphology and extent. To take advantage of Arecibo's sensitivity and small beam size, sources in this sample are fainter, smaller in angle, or in more crowded fields compared to those of the GBT HRDS. These Arecibo nebulae are some of the faintest H II regions ever detected in RRL emission. Our detection rate is 58%, which is low compared to the 95% detection rate for GBT HRDS targets. We derive kinematic distances to 23 of the Arecibo HRDS detections. Four nebulae have negative local standard of rest velocities and are thus unambiguously in the outer Galaxy. The remaining sources are at the tangent-point distance or farther. We identify a large, diffuse H II region complex that has an associated H I and {sup 13}CO shell. The {approx}90 pc diameter of the G52L nebula in this complex may be the largest Galactic H II region known, and yet it has escaped previous detection.

  13. Summary of CPAS Gen II Parachute Analysis

    NASA Technical Reports Server (NTRS)

    Morris, Aaron L.; Bledsoe, Kristin J.; Fraire, Usbaldo, Jr.; Moore, James W.; Olson, Leah M.; Ray, Eric

    2011-01-01

    The Orion spacecraft is currently under development by NASA and Lockheed Martin. Like Apollo, Orion will use a series of parachutes to slow its descent and splashdown safely. The Orion parachute system, known as the CEV Parachute Assembly System (CPAS), is being designed by NASA, the Engineering and Science Contract Group (ESCG), and Airborne Systems. The first generation (Gen I) of CPAS testing consisted of thirteen tests and was executed in the 2007-2008 timeframe. The Gen I tests provided an initial understanding of the CPAS parachutes. Knowledge gained from Gen I testing was used to plan the second generation of testing (Gen II). Gen II consisted of six tests: three singleparachute tests, designated as Main Development Tests, and three Cluster Development Tests. Gen II required a more thorough investigation into parachute performance than Gen I. Higher fidelity instrumentation, enhanced analysis methods and tools, and advanced test techniques were developed. The results of the Gen II test series are being incorporated into the CPAS design. Further testing and refinement of the design and model of parachute performance will occur during the upcoming third generation of testing (Gen III). This paper will provide an overview of the developments in CPAS analysis following the end of Gen I, including descriptions of new tools and techniques as well as overviews of the Gen II tests.

  14. Reddening and extinction towards H II regions

    NASA Technical Reports Server (NTRS)

    Caplan, James; Deharveng, Lise

    1989-01-01

    The light emitted by the gas in H II regions is attenuated by dust. This extinction can be measured by comparing H alpha, H beta, and radio continuum fluxes, since the intrinsic ratios of the Balmer line and thermal radio continuum emissivities are nearly constant for reasonable conditions in H II regions. In the case of giant extragalactic H II regions, the extinction was found to be considerably greater than expected. The dust between the Earth and the emitting gas may have an optical thickness which varies. The dust may be close enough to the source that scattered light contributes to the flux, or the dust may be actually mixed with the emitting gas. It is difficult to decide which configuration is correct. A rediscussion of this question in light of recent observations, with the Fabry-Perot spectrophotometers, of the large Galactic H II region is presented. The color excesses are compared for stars embedded in these H II regions with those derived (assuming the standard law) from the nebular extinction and reddening.

  15. PEP-II injection timing and controls

    SciTech Connect

    Bharadwaj, V.; Browne, M.; Crane, M.; Gromme, T.; Himel, T.; Ross, M.; Stanek, M.; Ronan, M.

    1997-07-01

    Hardware has been built and software written and incorporated in the existing SLC accelerator control system to control injection of beam pulses from the accelerator into the PEP-II storage rings currently under construction. Hardware includes a CAMAC module to delay the machine timing fiducial in order that a beam pulse extracted from a damping ring will be injected into a selected group of four 476 MHz buckets in a PEP-II ring. Further timing control is accomplished by shifting the phase of the bunches stored in the damping rings before extraction while leaving the phase of the PEP-II stored beam unchanged. The software which drives timing devices on a pulse-to-pulse basis relies on a dedicated communication link on which one scheduling microprocessor broadcasts a 128-bit message to all distributed control microprocessors at 360 Hz. PEP-II injection will be driven by the scheduling microprocessor according to lists specifying bucket numbers in arbitrary order, and according to scheduling constraints maximizing the useful beam delivered to the SLC collider currently in operation. These lists will be generated by a microprocessor monitoring the current stored per bucket in each of the PEP-II rings.

  16. Belle-II Experiment Network Requirements

    SciTech Connect

    Asner, David; Bell, Greg; Carlson, Tim; Cowley, David; Dart, Eli; Erwin, Brock; Godang, Romulus; Hara, Takanori; Johnson, Jerry; Johnson, Ron; Johnston, Bill; Dam, Kerstin Kleese-van; Kaneko, Toshiaki; Kubota, Yoshihiro; Kuhr, Thomas; McCoy, John; Miyake, Hideki; Monga, Inder; Nakamura, Motonori; Piilonen, Leo; Pordes, Ruth; Ray, Douglas; Russell, Richard; Schram, Malachi; Schroeder, Jim; Sevior, Martin; Singh, Surya; Suzuki, Soh; Sasaki, Takashi; Williams, Jim

    2013-05-28

    The Belle experiment, part of a broad-based search for new physics, is a collaboration of ~400 physicists from 55 institutions across four continents. The Belle detector is located at the KEKB accelerator in Tsukuba, Japan. The Belle detector was operated at the asymmetric electron-positron collider KEKB from 1999-2010. The detector accumulated more than 1 ab-1 of integrated luminosity, corresponding to more than 2 PB of data near 10 GeV center-of-mass energy. Recently, KEK has initiated a $400 million accelerator upgrade to be called SuperKEKB, designed to produce instantaneous and integrated luminosity two orders of magnitude greater than KEKB. The new international collaboration at SuperKEKB is called Belle II. The first data from Belle II/SuperKEKB is expected in 2015. In October 2012, senior members of the Belle-II collaboration gathered at PNNL to discuss the computing and neworking requirements of the Belle-II experiment with ESnet staff and other computing and networking experts. The day-and-a-half-long workshop characterized the instruments and facilities used in the experiment, the process of science for Belle-II, and the computing and networking equipment and configuration requirements to realize the full scientific potential of the collaboration's work.

  17. Mesospheric ozone measurements by SAGE II

    NASA Astrophysics Data System (ADS)

    Chu, D. A.; Cunnold, D. M.

    1994-04-01

    SAGE II observations of ozone at sunrise and sunset (solar zenith angle = 90 deg) at approximately the same tropical latitude and on the same day exhibit larger concentrations at sunrise than at sunset between 55 and 65 km. Because of the rapid conversion between atomic oxygen and ozone, the onion-peeling scheme used in SAGE II retrievals, which is based on an assumption of constant ozone, is invalid. A one-dimensional photochemical model is used to simulate the diurnal variation of ozone particularly within the solar zenith angle of 80 deg - 100 deg. This model indicates that the retrieved SAGE II sunrise and sunset ozone values are both overestimated. The Chapman reactions produce an adequate simulation of the ozone sunrise/sunset ratio only below 60 km, while above 60 km this ratio is highly affected by the odd oxygen loss due to odd hydrogen reactions, particularly OH. The SAGE II ozone measurements are in excellent agreement with model results to which an onion peeling procedure is applied. The SAGE II ozone observations provide information on the mesospheric chemistry not only through the ozone profile averages but also from the sunrise/sunset ratio.

  18. Mesospheric ozone measurements by SAGE II

    NASA Technical Reports Server (NTRS)

    Chu, D. A.; Cunnold, D. M.

    1994-01-01

    SAGE II observations of ozone at sunrise and sunset (solar zenith angle = 90 deg) at approximately the same tropical latitude and on the same day exhibit larger concentrations at sunrise than at sunset between 55 and 65 km. Because of the rapid conversion between atomic oxygen and ozone, the onion-peeling scheme used in SAGE II retrievals, which is based on an assumption of constant ozone, is invalid. A one-dimensional photochemical model is used to simulate the diurnal variation of ozone particularly within the solar zenith angle of 80 deg - 100 deg. This model indicates that the retrieved SAGE II sunrise and sunset ozone values are both overestimated. The Chapman reactions produce an adequate simulation of the ozone sunrise/sunset ratio only below 60 km, while above 60 km this ratio is highly affected by the odd oxygen loss due to odd hydrogen reactions, particularly OH. The SAGE II ozone measurements are in excellent agreement with model results to which an onion peeling procedure is applied. The SAGE II ozone observations provide information on the mesospheric chemistry not only through the ozone profile averages but also from the sunrise/sunset ratio.

  19. Centrifuge workers study. Phase II, completion report

    SciTech Connect

    Wooten, H.D.

    1994-09-01

    Phase II of the Centrifuge Workers Study was a follow-up to the Phase I efforts. The Phase I results had indicated a higher risk than expected among centrifuge workers for developing bladder cancer when compared with the risk in the general population for developing this same type of cancer. However, no specific agent could be identified as the causative agent for these bladder cancers. As the Phase II Report states, Phase I had been limited to workers who had the greatest potential for exposure to substances used in the centrifuge process. Phase II was designed to expand the survey to evaluate the health of all employees who had ever worked in Centrifuge Program Departments 1330-1339 but who had not been interviewed in Phase I. Employees in analytical laboratories and maintenance departments who provided support services for the Centrifuge Program were also included in Phase II. In December 1989, the Oak Ridge Associated Universities (ORAU), now known as Oak Ridge Institute for Science and Education (ORISE), was contracted to conduct a follow-up study (Phase II). Phase H of the Centrifuge Workers Study expanded the survey to include all former centrifuge workers who were not included in Phase I. ORISE was chosen because they had performed the Phase I tasks and summarized the corresponding survey data therefrom.

  20. PIP-II Status and Strategy

    SciTech Connect

    Holmes, Stephen; Derwent, Paul; Lebedev, Valeri; Mishra, Shekhar; Mitchell, Donald; Yakovlev, Vyacheslav P.

    2015-06-01

    Proton Improvement Plan-II (PIP-II) is the centerpiece of Fermilab's plan for upgrading the accelerator complex to establish the leading facility in the world for particle physics research based on intense proton beams. PIP-II has been developed to provide 1.2 MW of proton beam power at the start of operations of the Long Baseline Neutrino Facility (LBNF), while simultaneously providing a platform for eventual extension of LBNE beam power to >2MW and enabling future initiatives in rare processes research based on high duty factor/higher beam power operations. PIP-II is based on the construction of a new 800 MeV superconducting linac, augmented by improvements to the existing Booster, Recycler, and Main Injector complex. PIP-II is currently in the development stage with an R&D program underway targeting the front end and superconducting RF acceleration technologies. This paper will describe the status of the PIPII conceptual development, the associated technology R&D programs, and the strategy for project implementation.