Processing and analysis techniques involving in-vessel material generation

DOEpatents

Schabron, John F [Laramie, WY; Rovani, Jr., Joseph F.

2012-09-25

In at least one embodiment, the inventive technology relates to in-vessel generation of a material from a solution of interest as part of a processing and/or analysis operation. Preferred embodiments of the in-vessel material generation (e.g., in-vessel solid material generation) include precipitation; in certain embodiments, analysis and/or processing of the solution of interest may include dissolution of the material, perhaps as part of a successive dissolution protocol using solvents of increasing ability to dissolve. Applications include, but are by no means limited to estimation of a coking onset and solution (e.g., oil) fractionating.

Next-generation fiber lasers enabled by high-performance components

NASA Astrophysics Data System (ADS)

Kliner, D. A. V.; Victor, B.; Rivera, C.; Fanning, G.; Balsley, D.; Farrow, R. L.; Kennedy, K.; Hampton, S.; Hawke, R.; Soukup, E.; Reynolds, M.; Hodges, A.; Emery, J.; Brown, A.; Almonte, K.; Nelson, M.; Foley, B.; Dawson, D.; Hemenway, D. M.; Urbanek, W.; DeVito, M.; Bao, L.; Koponen, J.; Gross, K.

2018-02-01

Next-generation industrial fiber lasers enable challenging applications that cannot be addressed with legacy fiber lasers. Key features of next-generation fiber lasers include robust back-reflection protection, high power stability, wide power tunability, high-speed modulation and waveform generation, and facile field serviceability. These capabilities are enabled by high-performance components, particularly pump diodes and optical fibers, and by advanced fiber laser designs. We summarize the performance and reliability of nLIGHT diodes, fibers, and next-generation industrial fiber lasers at power levels of 500 W - 8 kW. We show back-reflection studies with up to 1 kW of back-reflected power, power-stability measurements in cw and modulated operation exhibiting sub-1% stability over a 5 - 100% power range, and high-speed modulation (100 kHz) and waveform generation with a bandwidth 20x higher than standard fiber lasers. We show results from representative applications, including cutting and welding of highly reflective metals (Cu and Al) for production of Li-ion battery modules and processing of carbon fiber reinforced polymers.

Review of Research on Low-Profile Vortex Generators to Control Boundary-Layer Separation

NASA Technical Reports Server (NTRS)

Lin, John C.

2002-01-01

An in-depth review of boundary-layer flow-separation control by a passive method using low-profile vortex generators is presented. The generators are defined as those with a device height between 10% and 50% of the boundary layer thickness. Key results are presented for several research efforts, all of which were performed within the past decade and a half where the majority of these works emphasize experimentation with some recent efforts on numerical simulations. Topics of discussion consist of both basic fluid dynamics and applied aerodynamics research. The fluid dynamics research includes comparative studies on separation control effectiveness as well as device-induced vortex characterization and correlation. The comparative studies cover the controlling of low-speed separated flows in adverse pressure gradient and supersonic shock-induced separation. The aerodynamics research includes several applications for aircraft performance enhancement and covers a wide range of speeds. Significant performance improvements are achieved through increased lift and/or reduced drag for various airfoils-low-Reynolds number, high-lift, and transonic-as well as highly swept wings. Performance enhancements for non-airfoil applications include aircraft interior noise reduction, inlet flow distortion alleviation inside compact ducts, and a more efficient overwing fairing. The low-profile vortex generators are best for being applied to applications where flow-separation locations are relatively fixed and the generators can be placed reasonably close upstream of the separation. Using the approach of minimal near-wall proturbances through substantially reduced device height, these devices can produce streamwise vortices just strong enough to overcome the separation without unnecessarily persisting within the boundary layer once the flow-control objective is achieved. Practical advantages of low-profile vortex generators, such as their inherent simplicity and low device drag, are demonstrated to be critically important for many applications as well.

Applications of nanotechnology, next generation sequencing and microarrays in biomedical research.

PubMed

Elingaramil, Sauli; Li, Xiaolong; He, Nongyue

2013-07-01

Next-generation sequencing technologies, microarrays and advances in bio nanotechnology have had an enormous impact on research within a short time frame. This impact appears certain to increase further as many biomedical institutions are now acquiring these prevailing new technologies. Beyond conventional sampling of genome content, wide-ranging applications are rapidly evolving for next-generation sequencing, microarrays and nanotechnology. To date, these technologies have been applied in a variety of contexts, including whole-genome sequencing, targeted re sequencing and discovery of transcription factor binding sites, noncoding RNA expression profiling and molecular diagnostics. This paper thus discusses current applications of nanotechnology, next-generation sequencing technologies and microarrays in biomedical research and highlights the transforming potential these technologies offer.

Reducing gas generators and methods for generating a reducing gas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scotto, Mark Vincent; Perna, Mark Anthony

One embodiment of the present invention is a unique reducing gas generator. Another embodiment is a unique method for generating a reducing gas. Other embodiments include apparatuses, systems, devices, hardware, methods, and combinations for generating reducing gas. Further embodiments, forms, features, aspects, benefits, and advantages of the present application will become apparent from the description and figures provided herewith.

Multispectral Remote Sensing of the Earth and Environment Using KHawk Unmanned Aircraft Systems

NASA Astrophysics Data System (ADS)

Gowravaram, Saket

This thesis focuses on the development and testing of the KHawk multispectral remote sensing system for environmental and agricultural applications. KHawk Unmanned Aircraft System (UAS), a small and low-cost remote sensing platform, is used as the test bed for aerial video acquisition. An efficient image geotagging and photogrammetric procedure for aerial map generation is described, followed by a comprehensive error analysis on the generated maps. The developed procedure is also used for generation of multispectral aerial maps including red, near infrared (NIR) and colored infrared (CIR) maps. A robust Normalized Difference Vegetation index (NDVI) calibration procedure is proposed and validated by ground tests and KHawk flight test. Finally, the generated aerial maps and their corresponding Digital Elevation Models (DEMs) are used for typical application scenarios including prescribed fire monitoring, initial fire line estimation, and tree health monitoring.

Liquid metal magnetohydrodynamics (LMMHD) technology transfer feasibility study. Volume 1: Summary

NASA Technical Reports Server (NTRS)

Phen, R. L.; Hays, L. G.; Alper, M. E.

1973-01-01

The potential application of liquid metal magnetohydrodynamics (LMMHD) to central station utility power generation through the period to 1990 is examined. Included are: (1) a description of LMMHD and a review of its development status, (2) LMMHD preliminary design for application to central station utility power generation, (3) evaluation of LMMHD in comparison with conventional and other advanced power generation systems and (4) a technology development plan. One of the major conclusions found is that the most economic and technically feasible application of LMMHD is a topping cycle to a steam plant, taking advantage of high temperatures available but not usable by the steam cycle.

Thin film coatings for space electrical power system applications

NASA Technical Reports Server (NTRS)

Gulino, Daniel A.

1989-01-01

This paper examines some of the ways in which thin film coatings can play a role in aerospace applications. Space systems discussed include photovoltaic and solar dynamic electric power generation systems, including applications in environmental protection, thermal energy storage, and radiator emittance enhancement. Potential applications of diamondlike films to both atmospheric and space based systems are examined. Also, potential uses of thin films of the recently discovered high-temperature superconductive materials are discussed.

Thin film coatings for space electrical power system applications

NASA Technical Reports Server (NTRS)

Gulino, Daniel A.

1988-01-01

This paper examines some of the ways in which thin film coatings can play a role in aerospace applications. Space systems discussed include photovoltaic and solar dynamic electric power generation systems, including applications in environmental protection, thermal energy storage, and radiator emittance enhancement. Potential applications of diamondlike films to both atmospheric and space based systems are examined. Also, potential uses of thin films of the recently discovered high-temperature superconductive materials are discussed.

Applicability of STEM-RTG and High-Power SRG Power Systems to the Discovery and Scout Mission Capabilities Expansion (DSMCE) Study of ASRG-Based Missions

NASA Technical Reports Server (NTRS)

Colozza, Anthony J.; Cataldo, Robert L.

2015-01-01

This study looks at the applicability of utilizing the Segmented Thermoelectric Modular Radioisotope Thermoelectric Generator (STEM-RTG) or a high-power radioisotope generator to replace the Advanced Stirling Radioisotope Generator (ASRG), which had been identified as the baseline power system for a number of planetary exploration mission studies. Nine different Discovery-Class missions were examined to determine the applicability of either the STEM-RTG or the high-power SRG power systems in replacing the ASRG. The nine missions covered exploration across the solar system and included orbiting spacecraft, landers and rovers. Based on the evaluation a ranking of the applicability of each alternate power system to the proposed missions was made.

Perspectives of shaped pulses for EPR spectroscopy

NASA Astrophysics Data System (ADS)

Spindler, Philipp E.; Schöps, Philipp; Kallies, Wolfgang; Glaser, Steffen J.; Prisner, Thomas F.

2017-07-01

This article describes current uses of shaped pulses, generated by an arbitrary waveform generator, in the field of EPR spectroscopy. We show applications of sech/tanh and WURST pulses to dipolar spectroscopy, including new pulse schemes and procedures, and discuss the more general concept of optimum-control-based pulses for applications in EPR spectroscopy. The article also describes a procedure to correct for experimental imperfections, mostly introduced by the microwave resonator, and discusses further potential applications and limitations of such pulses.

NASA/NREN: Next Generation Internet (NGI) Activities

NASA Technical Reports Server (NTRS)

desJardins, Richard; Freeman, Ken

1998-01-01

Various issues associated with next generation internet (NGI) and the NREN (NASA Research and Education Network) activities are presented in viewgraph form. Specific topics include: 1) NREN architecture; 2) NREN applications; and 3) NREN applied research.

Cycloconverter on the all-electric airplane

NASA Astrophysics Data System (ADS)

Webb, R. C.

1983-06-01

This paper discusses the application of a cycloconverter to a permanent magnet generator. Recent developments, advanced concepts, and advanced technology systems will be covered. Recent developments include permanent magnets, permanent magnet motors and generators, and power semiconductors.

Distributed operating system for NASA ground stations

NASA Technical Reports Server (NTRS)

Doyle, John F.

1987-01-01

NASA ground stations are characterized by ever changing support requirements, so application software is developed and modified on a continuing basis. A distributed operating system was designed to optimize the generation and maintenance of those applications. Unusual features include automatic program generation from detailed design graphs, on-line software modification in the testing phase, and the incorporation of a relational database within a real-time, distributed system.

77 FR 20817 - Diamond State Generation Partners, LLC; Supplemental Notice That Initial Market-Based Rate Filing...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER12-1383-000] Diamond State Generation Partners, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for... Diamond State Generation Partners, LLC's application for market-based rate authority, with an accompanying...

CD-ROM Based Multimedia Homework Solutions and Self Test Generator.

ERIC Educational Resources Information Center

Rhodes, Jeffrey M.; Bell, Christopher C.

1998-01-01

Discusses a prototype multimedia application that was designed to help college students solve problems and generate practice tests for an economics textbook. Highlights include step-by-step problem solving; a friendly interface; student tracking; inexpensive development costs; examples of screen displays; and generating random, scored tests on…

Multi-Resolution Unstructured Grid-Generation for Geophysical Applications on the Sphere

NASA Technical Reports Server (NTRS)

Engwirda, Darren

2015-01-01

An algorithm for the generation of non-uniform unstructured grids on ellipsoidal geometries is described. This technique is designed to generate high quality triangular and polygonal meshes appropriate for general circulation modelling on the sphere, including applications to atmospheric and ocean simulation, and numerical weather predication. Using a recently developed Frontal-Delaunay-refinement technique, a method for the construction of high-quality unstructured ellipsoidal Delaunay triangulations is introduced. A dual polygonal grid, derived from the associated Voronoi diagram, is also optionally generated as a by-product. Compared to existing techniques, it is shown that the Frontal-Delaunay approach typically produces grids with near-optimal element quality and smooth grading characteristics, while imposing relatively low computational expense. Initial results are presented for a selection of uniform and non-uniform ellipsoidal grids appropriate for large-scale geophysical applications. The use of user-defined mesh-sizing functions to generate smoothly graded, non-uniform grids is discussed.

Utilizing Linked Open Data Sources for Automatic Generation of Semantic Metadata

NASA Astrophysics Data System (ADS)

Nummiaho, Antti; Vainikainen, Sari; Melin, Magnus

In this paper we present an application that can be used to automatically generate semantic metadata for tags given as simple keywords. The application that we have implemented in Java programming language creates the semantic metadata by linking the tags to concepts in different semantic knowledge bases (CrunchBase, DBpedia, Freebase, KOKO, Opencyc, Umbel and/or WordNet). The steps that our application takes in doing so include detecting possible languages, finding spelling suggestions and finding meanings from amongst the proper nouns and common nouns separately. Currently, our application supports English, Finnish and Swedish words, but other languages could be included easily if the required lexical tools (spellcheckers, etc.) are available. The created semantic metadata can be of great use in, e.g., finding and combining similar contents, creating recommendations and targeting advertisements.

QoS for Real Time Applications over Next Generation Data Networks

NASA Technical Reports Server (NTRS)

Ivancic, William; Atiquzzaman, Mohammed; Bai, Haowei; Su, Hongjun; Chitri, Jyotsna; Ahamed, Faruque

2001-01-01

Viewgraphs on Qualtity of Service (QOS) for real time applications over next generation data networks are presented. The progress to date include: Task 1: QoS in Integrated Services over DiffServ networks (UD); Task 2: Interconnecting ATN with the next generation Internet (UD); Task 3: QoS in DiffServ over ATM (UD); Task 4: Improving Explicit Congestion Notification with the Mark-Front Strategy (OSU); Task 5: Multiplexing VBR over VBR (OSU); and Task 6: Achieving QoS for TCP traffic in Satellite Networks with Differentiated Services (OSU).

Photovoltaic Power Station with Ultracapacitors for Storage

NASA Technical Reports Server (NTRS)

Eichenberg, Dennis J.; Kolacz, John S.; Soltis, Richard F.; Tavernelli, Paul F.

2003-01-01

A solar photovoltaic power station in which ultracapacitors, rather than batteries, are used to store energy is discussed. Developments in the semiconductor industry have reduced the cost and increased the attainable efficiency of commercially available photovoltaic panels; as a result, photovoltaic generation of power for diverse applications has become practical. Photovoltaic generation can provide electric power in remote locations where electric power would otherwise not be available. Photovoltaic generation can also afford independence from utility systems. Applications include supplying power to scientific instruments and medical equipment in isolated geographical regions.

Improvements of high-power diode laser line generators open up new application fields

NASA Astrophysics Data System (ADS)

Meinschien, J.; Bayer, A.; Bruns, P.; Aschke, L.; Lissotschenko, V. N.

2009-02-01

Beam shaping improvements of line generators based on high power diode lasers lead to new application fields as hardening, annealing or cutting of various materials. Of special interest is the laser treatment of silicon. An overview of the wide variety of applications is presented with special emphasis of the relevance of unique laser beam parameters like power density and beam uniformity. Complementary to vision application and plastic processing, these new application markets become more and more important and can now be addressed by high power diode laser line generators. Herewith, a family of high power diode laser line generators is presented that covers this wide spectrum of application fields with very different requirements, including new applications as cutting of silicon or glass, as well as the beam shaping concepts behind it. A laser that generates a 5m long and 4mm wide homogeneous laser line is shown with peak intensities of 0.2W/cm2 for inspection of railway catenaries as well as a laser that generates a homogeneous intensity distribution of 60mm x 2mm size with peak intensities of 225W/cm2 for plastic processing. For the annealing of silicon surfaces, a laser was designed that generates an extraordinary uniform intensity distribution with residual inhomogeneities (contrast ratio) of less than 3% over a line length of 11mm and peak intensities of up to 75kW/cm2. Ultimately, a laser line is shown with a peak intensity of 250kW/cm2 used for cutting applications. Results of various application tests performed with the above mentioned lasers are discussed, particularly the surface treatment of silicon and the cutting of glass.

Quality of Service for Real-Time Applications Over Next Generation Data Networks

NASA Technical Reports Server (NTRS)

Atiquzzaman, Mohammed; Jain, Raj

2001-01-01

This project, which started on January 1, 2000, was funded by the NASA Glenn Research Center for duration of one year. The deliverables of the project included the following tasks: (1) Study of QoS mapping between the edge and core networks envisioned in the Next Generation networks will provide us with the QoS guarantees that can be obtained from next generation networks; (2) Buffer management techniques to provide strict guarantees to real-time end-to-end applications through preferential treatment to packets belonging to real-time applications. In particular, use of ECN to help reduce the loss on high bandwidth-delay product satellite networks needs to be studied; (3) Effect of Prioritized Packet Discard to increase goodput of the network and reduce the buffering requirements in the ATM switches; (4) Provision of new IP circuit emulation services over Satellite IP backbones using MPLS will be studied; and (5) Determine the architecture and requirements for internetworking ATN and the Next Generation Internet for real-time applications. The project has been completed on time. All the objectives and deliverables of the project have been completed. Research results obtained from this project have been published in a number of papers in journals, conferences, and technical reports, included in this document.

76 FR 69720 - Northampton Generating Company, L.P.; Supplemental Notice That Initial Market-Based Rate Filing...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-09

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER12-281-000] Northampton Generating Company, L.P.; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for... Northampton Generating Company, L.P.'s application for market-based rate authority, with an accompanying rate...

76 FR 23198 - Segregation of Lands-Renewable Energy

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-26

... could be used to carry the power generated from a specific wind or solar energy ROW project, and the... included in a pending or future wind or solar energy generation right- of-way (ROW) application, or public lands identified by the BLM for a potential future wind or solar energy generation ROW authorization...

Hybrid Power Management (HPM) Program Resulted in Several New Applications

NASA Technical Reports Server (NTRS)

Eichenberg, Dennis J.

2003-01-01

Hybrid Power Management (HPM) is the innovative integration of diverse, state-of-the-art power devices in an optimal configuration for space and terrestrial applications. The appropriate application and control of the various power devices significantly improves overall system performance and efficiency. The advanced power devices include ultracapacitors, fuel cells, and photovoltaics. HPM has extremely wide potential with applications from nanowatts to megawatts. Applications include power generation, transportation systems, biotechnology systems, and space power systems. HPM has the potential to significantly alleviate global energy concerns, improve the environment, and stimulate the economy.

Generation-V dual-Purkinje-image eyetracker

NASA Technical Reports Server (NTRS)

Crane, H. D.; Steele, C. M.

1985-01-01

Major advances characterize the Generation-V dual-Purkinje-image eyetracker compared with the Generation-III version previously described. These advances include a large reduction in size, major improvements in frequency response and noise level, automatic alignment to a subject, and automatic adjustment for different separation between the visual and optic axes, which can vary considerably from subject to subject. In a number of applications described in the paper, the eyetracker is coupled with other highly specialized optical devices. These applications include accurately stabilizing an image on a subject's retina; accurately simulating a visually dead retinal region (i.e., a scotoma) of arbitrary shape, size, and position; and, for clinical purposes, stabilizing the position of a laser coagulator beam on a patient's retina so that the point of contact is unaffected by the patient's own eye movements.

Automatic 3d Building Model Generations with Airborne LiDAR Data

NASA Astrophysics Data System (ADS)

Yastikli, N.; Cetin, Z.

2017-11-01

LiDAR systems become more and more popular because of the potential use for obtaining the point clouds of vegetation and man-made objects on the earth surface in an accurate and quick way. Nowadays, these airborne systems have been frequently used in wide range of applications such as DEM/DSM generation, topographic mapping, object extraction, vegetation mapping, 3 dimensional (3D) modelling and simulation, change detection, engineering works, revision of maps, coastal management and bathymetry. The 3D building model generation is the one of the most prominent applications of LiDAR system, which has the major importance for urban planning, illegal construction monitoring, 3D city modelling, environmental simulation, tourism, security, telecommunication and mobile navigation etc. The manual or semi-automatic 3D building model generation is costly and very time-consuming process for these applications. Thus, an approach for automatic 3D building model generation is needed in a simple and quick way for many studies which includes building modelling. In this study, automatic 3D building models generation is aimed with airborne LiDAR data. An approach is proposed for automatic 3D building models generation including the automatic point based classification of raw LiDAR point cloud. The proposed point based classification includes the hierarchical rules, for the automatic production of 3D building models. The detailed analyses for the parameters which used in hierarchical rules have been performed to improve classification results using different test areas identified in the study area. The proposed approach have been tested in the study area which has partly open areas, forest areas and many types of the buildings, in Zekeriyakoy, Istanbul using the TerraScan module of TerraSolid. The 3D building model was generated automatically using the results of the automatic point based classification. The obtained results of this research on study area verified that automatic 3D building models can be generated successfully using raw LiDAR point cloud data.

NASA Missions Enabled by Space Nuclear Systems

NASA Technical Reports Server (NTRS)

Scott, John H.; Schmidt, George R.

2009-01-01

This viewgraph presentation reviews NASA Space Missions that are enabled by Space Nuclear Systems. The topics include: 1) Space Nuclear System Applications; 2) Trade Space for Electric Power Systems; 3) Power Generation Specific Energy Trade Space; 4) Radioisotope Power Generation; 5) Radioisotope Missions; 6) Fission Power Generation; 7) Solar Powered Lunar Outpost; 8) Fission Powered Lunar Outpost; 9) Fission Electric Power Generation; and 10) Fission Nuclear Thermal Propulsion.

Power Generation by Harvesting Ambient Energy with a Micro-Electromagnetic Generator

DTIC Science & Technology

2009-03-01

more applicable at the micro scale are also being investigated including piezoelectric and electrostatics. Solar energy harvesting is a proven method. It...with IC circuitry. 6.2.7 Piezoelectric Research. In Chapter 2, energy harvesting through the use of piezoelectric materials was briefly discussed. A... piezoelectric harvesters require minimal movement for power generation, whereas an electromagnet generator generally requires significant mechanical motion in

Applications of Parsing Theory to Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Markosian, Lawrence Z.; Ager, Tryg A.

1983-01-01

Applications of an LR-1 parsing algorithm to intelligent programs for computer assisted instruction in symbolic logic and foreign languages are discussed. The system has been adequately used for diverse instructional applications, including analysis of student input, generation of pattern drills, and modeling the student's understanding of the…

Two-dimensional fluid droplet arrays generated using a single nozzle

DOEpatents

Lee, Eric R.; Perl, Martin L.

1999-11-02

Amplitudes of drive pulses received by a horizontally-placed dropper determine the horizontal displacements of droplets relative to an ejection aperture of the dropper. The drive pulses are varied such that the dropper generates a two-dimensional array of vertically-falling droplets. Vertical and horizontal interdroplet spacings may be varied in real time. Applications include droplet analysis experiments such as Millikan fractional charge searches and aerosol characterization, as well as material deposition applications.

Unstructured grid research and use at NASA Lewis Research Center

NASA Technical Reports Server (NTRS)

Potapczuk, Mark G.

1993-01-01

Computational fluid dynamics applications of grid research at LRC include inlets, nozzles, and ducts; turbomachinery; propellers - ducted and unducted; and aircraft icing. Some issues related to internal flow grid generation are resolution requirements on several boundaries, shock resolution vs. grid periodicity, grid spacing at blade/shroud gap, grid generation in turbine blade passages, and grid generation for inlet/nozzle geometries. Aircraft icing grid generation issues include (1) small structures relative to airfoil chord must be resolved; (2) excessive number of grid points in far-field using structured grid; and (3) grid must be recreated as ice shape grows.

Quality of Service for Real-Time Applications Over Next Generation Data Networks

NASA Technical Reports Server (NTRS)

Ivancic, William; Atiquzzaman, Mohammed; Bai, Haowei; Su, Hongjun; Jain, Raj; Duresi, Arjan; Goyal, Mukyl; Bharani, Venkata; Liu, Chunlei; Kota, Sastri

2001-01-01

This project, which started on January 1, 2000, was funded by NASA Glenn Research Center for duration of one year. The deliverables of the project included the following tasks: Study of QoS mapping between the edge and core networks envisioned in the Next Generation networks will provide us with the QoS guarantees that can be obtained from next generation networks. Buffer management techniques to provide strict guarantees to real-time end-to-end applications through preferential treatment to packets belonging to real-time applications. In particular, use of ECN to help reduce the loss on high bandwidth-delay product satellite networks needs to be studied. Effect of Prioritized Packet Discard to increase goodput of the network and reduce the buffering requirements in the ATM switches. Provision of new IP circuit emulation services over Satellite IP backbones using MPLS will be studied. Determine the architecture and requirements for internetworking ATN and the Next Generation Internet for real-time applications.

Improved resource use decisions and actions through remote sensing

NASA Technical Reports Server (NTRS)

Hill-Rowley, R.; Boylan, M.; Enslin, W.; Vlasin, R. D.

1975-01-01

Operational uses of remote sensing for improving management decisions and actions concerning resource uses are considered in terms of first generation, or direct-action; and second generation or indirect, delayed-action applications. From among applications completed during 1974-75, seven case studies are offered in illustration of the many contrasts which can be drawn between first and second generation application studies. These include: (1) multi-agency river basin planning; (2) corridor assessment and route location for highway location together with improvement of county-level planning decisions; (3) improving timber management practices; (4) enforcement of new state statutes; (5) county-wide open space preservation; (6) land value reappraisal relative to property tax equalization; and (7) optimizing agri-business processing plant locations.

Audio Spectrogram Representations for Processing with Convolutional Neural Networks

NASA Astrophysics Data System (ADS)

Wyse, L.

2017-05-01

One of the decisions that arise when designing a neural network for any application is how the data should be represented in order to be presented to, and possibly generated by, a neural network. For audio, the choice is less obvious than it seems to be for visual images, and a variety of representations have been used for different applications including the raw digitized sample stream, hand-crafted features, machine discovered features, MFCCs and variants that include deltas, and a variety of spectral representations. This paper reviews some of these representations and issues that arise, focusing particularly on spectrograms for generating audio using neural networks for style transfer.

Improved Electrolytic Hydrogen Peroxide Generator

NASA Technical Reports Server (NTRS)

James, Patrick I.

2005-01-01

An improved apparatus for the electrolytic generation of hydrogen peroxide dissolved in water has been developed. The apparatus is a prototype of H2O2 generators for the safe and effective sterilization of water, sterilization of equipment in contact with water, and other applications in which there is need for hydrogen peroxide at low concentration as an oxidant. Potential applications for electrolytic H2O2 generators include purification of water for drinking and for use in industrial processes, sanitation for hospitals and biotechnological industries, inhibition and removal of biofouling in heat exchangers, cooling towers, filtration units, and the treatment of wastewater by use of advanced oxidation processes that are promoted by H2O2.

An Exploratory Study of Thermoelectrostatic Power Generation for Space Flight Applications

NASA Technical Reports Server (NTRS)

Beam, Benjamin H.

1960-01-01

A study has been made of a process in which a solar heating cycle is combined with an electrostatic cycle for generating electrical power for space vehicle applications. The power unit, referred to as a thermoelectrostatic generator, is a thin film, solid dielectric capacitor alternately heated by solar radiation and cooled by radiant emission. The theory of operation to extract electrical power is presented. Results of an experiment to illustrate the principle are described. Estimates of the performance of this type of device in space in the vicinity of earth are included. Values of specific power of several kilowatts per kilogram of generator weight are calculated for such a device employing polyethylene terephthalate dielectric.

Yellow light generation by frequency doubling of a fiber oscillator

NASA Astrophysics Data System (ADS)

Bacher, Christoph; Oliveira, Ricardo; Nogueira, Rogério N.; Romano, Valerio; Ryser, Manuel

2016-04-01

Laser sources with light-emission in the yellow spectral range around 577nm are very favorable for a variety of applications. These include applications in astronomy, in ophthalmology or in quantum optics. The generation and amplification of 1154 nm light is not straight forward when using Yb-doped optical fibers, since lasing occurs preferentially around the gain-maximum of 1030 nm. We generate the radiation within a fiber Bragg grating (FBG) based cavity and focused on reducing the amplified spontaneous emission (ASE). After the cavity, the output is frequency doubled to 577nm by using a second harmonic crystal.

Waste minimization for commercial radioactive materials users generating low-level radioactive waste. Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fischer, D.K.; Gitt, M.; Williams, G.A.

1991-07-01

The objective of this document is to provide a resource for all states and compact regions interested in promoting the minimization of low-level radioactive waste (LLW). This project was initiated by the Commonwealth of Massachusetts, and Massachusetts waste streams have been used as examples; however, the methods of analysis presented here are applicable to similar waste streams generated elsewhere. This document is a guide for states/compact regions to use in developing a system to evaluate and prioritize various waste minimization techniques in order to encourage individual radioactive materials users (LLW generators) to consider these techniques in their own independent evaluations.more » This review discusses the application of specific waste minimization techniques to waste streams characteristic of three categories of radioactive materials users: (1) industrial operations using radioactive materials in the manufacture of commercial products, (2) health care institutions, including hospitals and clinics, and (3) educational and research institutions. Massachusetts waste stream characterization data from key radioactive materials users in each category are used to illustrate the applicability of various minimization techniques. The utility group is not included because extensive information specific to this category of LLW generators is available in the literature.« less

Waste minimization for commercial radioactive materials users generating low-level radioactive waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fischer, D.K.; Gitt, M.; Williams, G.A.

1991-07-01

The objective of this document is to provide a resource for all states and compact regions interested in promoting the minimization of low-level radioactive waste (LLW). This project was initiated by the Commonwealth of Massachusetts, and Massachusetts waste streams have been used as examples; however, the methods of analysis presented here are applicable to similar waste streams generated elsewhere. This document is a guide for states/compact regions to use in developing a system to evaluate and prioritize various waste minimization techniques in order to encourage individual radioactive materials users (LLW generators) to consider these techniques in their own independent evaluations.more » This review discusses the application of specific waste minimization techniques to waste streams characteristic of three categories of radioactive materials users: (1) industrial operations using radioactive materials in the manufacture of commercial products, (2) health care institutions, including hospitals and clinics, and (3) educational and research institutions. Massachusetts waste stream characterization data from key radioactive materials users in each category are used to illustrate the applicability of various minimization techniques. The utility group is not included because extensive information specific to this category of LLW generators is available in the literature.« less

Hybrid Power Management Program Continued

NASA Technical Reports Server (NTRS)

Eichenberg, Dennis J.

2002-01-01

Hybrid Power Management (HPM) is the innovative integration of diverse, state-of-the-art power devices in an optimal configuration for space and terrestrial applications. The appropriate application and control of the various power devices significantly improves overall system performance and efficiency. The advanced power devices include ultracapacitors and photovoltaics. HPM has extremely wide potential with applications including power-generation, transportation, biotechnology, and space power systems. It may significantly alleviate global energy concerns, improve the environment, and stimulate the economy.

GeneratorSE: A Sizing Tool for Variable-Speed Wind Turbine Generators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sethuraman, Latha; Dykes, Katherine L

This report documents a set of analytical models employed by the optimization algorithms within the GeneratorSE framework. The initial values and boundary conditions employed for the generation of the various designs and initial estimates for basic design dimensions, masses, and efficiency for the four different models of generators are presented and compared with empirical data collected from previous studies and some existing commercial turbines. These models include designs applicable for variable-speed, high-torque application featuring direct-drive synchronous generators and low-torque application featuring induction generators. In all of the four models presented, the main focus of optimization is electromagnetic design with themore » exception of permanent-magnet and wire-wound synchronous generators, wherein the structural design is also optimized. Thermal design is accommodated in GeneratorSE as a secondary attribute by limiting the winding current densities to acceptable limits. A preliminary validation of electromagnetic design was carried out by comparing the optimized magnetic loading against those predicted by numerical simulation in FEMM4.2, a finite-element software for analyzing electromagnetic and thermal physics problems for electrical machines. For direct-drive synchronous generators, the analytical models for the structural design are validated by static structural analysis in ANSYS.« less

Nanomaterials for Space Exploration Applications

NASA Technical Reports Server (NTRS)

Moloney, Padraig G.

2006-01-01

Nano-engineered materials are multi-functional materials with superior mechanical, thermal and electrical properties. Nanomaterials may be used for a variety of space exploration applications, including ultracapacitors, active/passive thermal management materials, and nanofiltration for water recovery. Additional applications include electrical power/energy storage systems, hybrid systems power generation, advanced proton exchange membrane fuel cells, and air revitalization. The need for nanomaterials and their growth, characterization, processing and space exploration applications is discussed. Data is presented for developing solid-supported amine adsorbents based on carbon nanotube materials and functionalization of nanomaterials is examined.

18 CFR 16.10 - Information to be provided by an applicant for new license: Filing requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... applicant's operating and load characteristics; and (C) The communities served or to be served, including... the contributions from the applicant's generation, purchases, and load modification measures (such as...; and (C) If load management measures are not viewed as resources, the effects of such measures on the...

18 CFR 16.10 - Information to be provided by an applicant for new license: Filing requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... applicant's operating and load characteristics; and (C) The communities served or to be served, including... the contributions from the applicant's generation, purchases, and load modification measures (such as...; and (C) If load management measures are not viewed as resources, the effects of such measures on the...

18 CFR 16.10 - Information to be provided by an applicant for new license: Filing requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... applicant's operating and load characteristics; and (C) The communities served or to be served, including... the contributions from the applicant's generation, purchases, and load modification measures (such as...; and (C) If load management measures are not viewed as resources, the effects of such measures on the...

18 CFR 16.10 - Information to be provided by an applicant for new license: Filing requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... applicant's operating and load characteristics; and (C) The communities served or to be served, including... the contributions from the applicant's generation, purchases, and load modification measures (such as...; and (C) If load management measures are not viewed as resources, the effects of such measures on the...

18 CFR 16.10 - Information to be provided by an applicant for new license: Filing requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... applicant's operating and load characteristics; and (C) The communities served or to be served, including... the contributions from the applicant's generation, purchases, and load modification measures (such as...; and (C) If load management measures are not viewed as resources, the effects of such measures on the...

Dual ion beam processed diamondlike films for industrial applications

NASA Technical Reports Server (NTRS)

Mirtich, M. J.; Kussmaul, M. T.; Banks, B. A.; Sovey, J. S.

1991-01-01

Single and dual beam ion source systems are used to generate amorphous diamondlike carbon (DLC) films, which were evaluated for a variety of applications including protective coatings on transmitting materials, power electronics as insulated gates and corrosion resistant barriers. A list of the desirable properties of DLC films along with potential applications are presented.

Motor/Generator and Inverter Characterization for Flywheel System Applications

NASA Technical Reports Server (NTRS)

Tamarcus, Jeffries L.

2004-01-01

The Advanced Electrical Systems Development Branch at NASA Glenn Research Center (GRC) has been involved in the research and development of high speed flywheels systems for satellite energy storage and attitude applications. These flywheels will serve as replacement for chemical nickel hydrogen, nickel cadmium batteries and gyroscopic wheels. The advantages of using flywheel systems for energy storage on satellites are high energy density, high power density, long life, deep depth of discharge, and broad operating temperature ranges. A flywheel system for space applications consist of a number of flywheel modules, the motor/generator and magnetic bearing, and an electronics package. The motor/generator electronics package includes a pulse-width modulated inverter that drives the flywheel permanent magnet motor/generator located at one end of the shaft. This summer, I worked under the direct supervision of my mentor, Walter Santiago, and the goal for this summer was to characterize motor generator and inverter attributes in order to increase their viability as a more efficient energy storage source for space applications. To achieve this goal, magnetic field measurements around the motor/generator permanent magnet and the impedance of the motor/generator three phase windings were characterized, and a recreation of the inverter pulse width modulated control system was constructed. The Flywheel modules for space use are designed to maximize energy density and minimize loss, and attaining these values will aid in locating and reducing losses within the flywheel system as a whole, making flywheel technology more attractive for use as energy storage in future space applications.

Concept For Generation Of Long Pseudorandom Sequences

NASA Technical Reports Server (NTRS)

Wang, C. C.

1990-01-01

Conceptual very-large-scale integrated (VLSI) digital circuit performs exponentiation in finite field. Algorithm that generates unusually long sequences of pseudorandom numbers executed by digital processor that includes such circuits. Concepts particularly advantageous for such applications as spread-spectrum communications, cryptography, and generation of ranging codes, synthetic noise, and test data, where usually desirable to make pseudorandom sequences as long as possible.

GASPRNG: GPU accelerated scalable parallel random number generator library

NASA Astrophysics Data System (ADS)

Gao, Shuang; Peterson, Gregory D.

2013-04-01

Graphics processors represent a promising technology for accelerating computational science applications. Many computational science applications require fast and scalable random number generation with good statistical properties, so they use the Scalable Parallel Random Number Generators library (SPRNG). We present the GPU Accelerated SPRNG library (GASPRNG) to accelerate SPRNG in GPU-based high performance computing systems. GASPRNG includes code for a host CPU and CUDA code for execution on NVIDIA graphics processing units (GPUs) along with a programming interface to support various usage models for pseudorandom numbers and computational science applications executing on the CPU, GPU, or both. This paper describes the implementation approach used to produce high performance and also describes how to use the programming interface. The programming interface allows a user to be able to use GASPRNG the same way as SPRNG on traditional serial or parallel computers as well as to develop tightly coupled programs executing primarily on the GPU. We also describe how to install GASPRNG and use it. To help illustrate linking with GASPRNG, various demonstration codes are included for the different usage models. GASPRNG on a single GPU shows up to 280x speedup over SPRNG on a single CPU core and is able to scale for larger systems in the same manner as SPRNG. Because GASPRNG generates identical streams of pseudorandom numbers as SPRNG, users can be confident about the quality of GASPRNG for scalable computational science applications. Catalogue identifier: AEOI_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEOI_v1_0.html Program obtainable from: CPC Program Library, Queen’s University, Belfast, N. Ireland Licensing provisions: UTK license. No. of lines in distributed program, including test data, etc.: 167900 No. of bytes in distributed program, including test data, etc.: 1422058 Distribution format: tar.gz Programming language: C and CUDA. Computer: Any PC or workstation with NVIDIA GPU (Tested on Fermi GTX480, Tesla C1060, Tesla M2070). Operating system: Linux with CUDA version 4.0 or later. Should also run on MacOS, Windows, or UNIX. Has the code been vectorized or parallelized?: Yes. Parallelized using MPI directives. RAM: 512 MB˜ 732 MB (main memory on host CPU, depending on the data type of random numbers.) / 512 MB (GPU global memory) Classification: 4.13, 6.5. Nature of problem: Many computational science applications are able to consume large numbers of random numbers. For example, Monte Carlo simulations are able to consume limitless random numbers for the computation as long as resources for the computing are supported. Moreover, parallel computational science applications require independent streams of random numbers to attain statistically significant results. The SPRNG library provides this capability, but at a significant computational cost. The GASPRNG library presented here accelerates the generators of independent streams of random numbers using graphical processing units (GPUs). Solution method: Multiple copies of random number generators in GPUs allow a computational science application to consume large numbers of random numbers from independent, parallel streams. GASPRNG is a random number generators library to allow a computational science application to employ multiple copies of random number generators to boost performance. Users can interface GASPRNG with software code executing on microprocessors and/or GPUs. Running time: The tests provided take a few minutes to run.

Percy Thomas wind generator designs

NASA Technical Reports Server (NTRS)

Lines, C. W.

1973-01-01

The technical and economic feasibilities of constructing a windpowered generator with a capacity of 2,000 to 4,000 kilowatt are considered. Possible benefits of an integrated wind generating electric energy source in an electric utility network are elaborated. Applications of a windpowered waterpump, including its use as a pumping source for hydroelectric pump storage operations, are also mentioned. It is concluded that the greatest potential of the wind generator is to generate heat directly and not conversion to electricity and then to heat.

Study to perform preliminary experiments to evaluate particle generation and characterization techniques for zero-gravity cloud physics experiments

NASA Technical Reports Server (NTRS)

Katz, U.

1982-01-01

Methods of particle generation and characterization with regard to their applicability for experiments requiring cloud condensation nuclei (CCN) of specified properties were investigated. Since aerosol characterization is a prerequisite to assessing performance of particle generation equipment, techniques for characterizing aerosol were evaluated. Aerosol generation is discussed, and atomizer and photolytic generators including preparation of hydrosols (used with atomizers) and the evaluation of a flight version of an atomizer are studied.

Dynamic Imbalance Would Counter Offcenter Thrust

NASA Technical Reports Server (NTRS)

Mccanna, Jason

1994-01-01

Dynamic imbalance generated by offcenter thrust on rotating body eliminated by shifting some of mass of body to generate opposing dynamic imbalance. Technique proposed originally for spacecraft including massive crew module connected via long, lightweight intermediate structure to massive engine module, such that artificial gravitation in crew module generated by rotating spacecraft around axis parallel to thrust generated by engine. Also applicable to dynamic balancing of rotating terrestrial equipment to which offcenter forces applied.

The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button.

PubMed

Swertz, Morris A; Dijkstra, Martijn; Adamusiak, Tomasz; van der Velde, Joeri K; Kanterakis, Alexandros; Roos, Erik T; Lops, Joris; Thorisson, Gudmundur A; Arends, Danny; Byelas, George; Muilu, Juha; Brookes, Anthony J; de Brock, Engbert O; Jansen, Ritsert C; Parkinson, Helen

2010-12-21

There is a huge demand on bioinformaticians to provide their biologists with user friendly and scalable software infrastructures to capture, exchange, and exploit the unprecedented amounts of new *omics data. We here present MOLGENIS, a generic, open source, software toolkit to quickly produce the bespoke MOLecular GENetics Information Systems needed. The MOLGENIS toolkit provides bioinformaticians with a simple language to model biological data structures and user interfaces. At the push of a button, MOLGENIS' generator suite automatically translates these models into a feature-rich, ready-to-use web application including database, user interfaces, exchange formats, and scriptable interfaces. Each generator is a template of SQL, JAVA, R, or HTML code that would require much effort to write by hand. This 'model-driven' method ensures reuse of best practices and improves quality because the modeling language and generators are shared between all MOLGENIS applications, so that errors are found quickly and improvements are shared easily by a re-generation. A plug-in mechanism ensures that both the generator suite and generated product can be customized just as much as hand-written software. In recent years we have successfully evaluated the MOLGENIS toolkit for the rapid prototyping of many types of biomedical applications, including next-generation sequencing, GWAS, QTL, proteomics and biobanking. Writing 500 lines of model XML typically replaces 15,000 lines of hand-written programming code, which allows for quick adaptation if the information system is not yet to the biologist's satisfaction. Each application generated with MOLGENIS comes with an optimized database back-end, user interfaces for biologists to manage and exploit their data, programming interfaces for bioinformaticians to script analysis tools in R, Java, SOAP, REST/JSON and RDF, a tab-delimited file format to ease upload and exchange of data, and detailed technical documentation. Existing databases can be quickly enhanced with MOLGENIS generated interfaces using the 'ExtractModel' procedure. The MOLGENIS toolkit provides bioinformaticians with a simple model to quickly generate flexible web platforms for all possible genomic, molecular and phenotypic experiments with a richness of interfaces not provided by other tools. All the software and manuals are available free as LGPLv3 open source at http://www.molgenis.org.

Gas-Phase Oxidation via Ion/Ion Reactions: Pathways and Applications

NASA Astrophysics Data System (ADS)

Pilo, Alice L.; Zhao, Feifei; McLuckey, Scott A.

2017-06-01

Here, we provide an overview of pathways available upon the gas-phase oxidation of peptides and DNA via ion/ion reactions and explore potential applications of these chemistries. The oxidation of thioethers (i.e., methionine residues and S-alkyl cysteine residues), disulfide bonds, S-nitrosylated cysteine residues, and DNA to the [M+H+O]+ derivative via ion/ion reactions with periodate and peroxymono-sulfate anions is demonstrated. The oxidation of neutral basic sites to various oxidized structures, including the [M+H+O]+, [M-H]+, and [M-H-NH3]+ species, via ion/ion reactions is illustrated and the oxidation characteristics of two different oxidizing reagents, periodate and persulfate anions, are compared. Lastly, the highly efficient generation of molecular radical cations via ion/ion reactions with sulfate radical anion is summarized. Activation of the newly generated molecular radical peptide cations results in losses of various neutral side chains, several of which generate dehydroalanine residues that can be used to localize the amino acid from which the dehydroalanine was generated. The chemistries presented herein result in a diverse range of structures that can be used for a variety of applications, including the identification and localization of S-alkyl cysteine residues, the oxidative cleavage of disulfide bonds, and the generation of molecular radical cations from even-electron doubly protonated peptides. [Figure not available: see fulltext.

Application of circular consensus sequencing and network analysis to characterize the bovine IgG repertoire

USDA-ARS?s Scientific Manuscript database

Background: Vertebrate immune systems generate diverse repertoires of antibodies capable of mediating response to a variety of antigens. Next generation sequencing methods provide unique approaches to a number of immuno-based research areas including antibody discovery and engineering, disease surve...

Lessons from Interspecies Mammalian Chimeras.

PubMed

Suchy, Fabian; Nakauchi, Hiromitsu

2017-10-06

As chimeras transform from beasts of Greek mythology into tools of contemporary bioscience, secrets of developmental biology and evolutionary divergence are being revealed. Recent advances in stem cell biology and interspecies chimerism have generated new models with extensive basic and translational applications, including generation of transplantable, patient-specific organs.

Hardware Acceleration for Cyber Security

DTIC Science & Technology

2010-11-01

perform different approaches. It includes behavioral analysis, by means of NetFlow monitoring, as well as packet content analysis, so called Deep...Interface (API). The example of such application is NetFlow exporter described in [5]. • We provide modified libpcap library using libsze2 API. This...cards. The software applications using NIFIC include FlowMon NetFlow /IPFIX generator, Wireshark packet analyzer, iptables - Linux kernel firewall, deep

Hockey-stick steam generator for LMFBR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hallinan, G.J.; Svedlund, P.E.

1981-01-01

This paper presents the criteria and evaluation leading to the selection of the Hockey Stick Steam Generator Concept and subsequent development of that concept for LMFBR application. The selection process and development of the Modular Steam Generator (MSG) is discussed, including the extensive test programs that culminated in the manufacture and test of a 35 MW(t) Steam Generator. The design of the CRBRP Steam Generator is described, emphasizing the current status and a review of the critical structural areas. CRBRP steam generator development tests are evaluated, with a discussion of test objectives and rating of the usefulness of test resultsmore » to the CRBRP prototype design. Manufacturing experience and status of the CRBRP prototype and plant units is covered. The scaleup of the Hockey Stick concept to large commercial plant application is presented, with an evaluation of scaleup limitations, transient effects, and system design implications.« less

Selecting an Architecture for a Safety-Critical Distributed Computer System with Power, Weight and Cost Considerations

NASA Technical Reports Server (NTRS)

Torres-Pomales, Wilfredo

2014-01-01

This report presents an example of the application of multi-criteria decision analysis to the selection of an architecture for a safety-critical distributed computer system. The design problem includes constraints on minimum system availability and integrity, and the decision is based on the optimal balance of power, weight and cost. The analysis process includes the generation of alternative architectures, evaluation of individual decision criteria, and the selection of an alternative based on overall value. In this example presented here, iterative application of the quantitative evaluation process made it possible to deliberately generate an alternative architecture that is superior to all others regardless of the relative importance of cost.

Application for managing model-based material properties for simulation-based engineering

DOEpatents

Hoffman, Edward L [Alameda, CA

2009-03-03

An application for generating a property set associated with a constitutive model of a material includes a first program module adapted to receive test data associated with the material and to extract loading conditions from the test data. A material model driver is adapted to receive the loading conditions and a property set and operable in response to the loading conditions and the property set to generate a model response for the material. A numerical optimization module is adapted to receive the test data and the model response and operable in response to the test data and the model response to generate the property set.

Development of Web-Based Learning Application for Generation Z

ERIC Educational Resources Information Center

Hariadi, Bambang; Dewiyani Sunarto, M. J.; Sudarmaningtyas, Pantjawati

2016-01-01

This study aimed to develop a web-based learning application as a form of learning revolution. The form of learning revolution includes the provision of unlimited teaching materials, real time class organization, and is not limited by time or place. The implementation of this application is in the form of hybrid learning by using Google Apps for…

Decision generation tools and Bayesian inference

NASA Astrophysics Data System (ADS)

Jannson, Tomasz; Wang, Wenjian; Forrester, Thomas; Kostrzewski, Andrew; Veeris, Christian; Nielsen, Thomas

2014-05-01

Digital Decision Generation (DDG) tools are important software sub-systems of Command and Control (C2) systems and technologies. In this paper, we present a special type of DDGs based on Bayesian Inference, related to adverse (hostile) networks, including such important applications as terrorism-related networks and organized crime ones.

Power from Radioisotopes, Understanding the Atom Series.

ERIC Educational Resources Information Center

Corliss, William R.; Mead, Robert L.

This 1971 revision deals with radioisotopes and their use in power generators. Early developments and applications for the Systems for Nuclear Auxiliary Power (SNAP) and Radioisotope Thermoelectric Generators (RTGs) are reviewed. Present uses in space and on earth are included. Uses in space are as power sources in various satellites and space…

Engineered Biocompatible Nanoparticles for in Vivo Imaging Applications

PubMed Central

2010-01-01

Iron−platinum alloy nanoparticles (FePt NPs) are extremely promising candidates for the next generation of contrast agents for magnetic resonance (MR) diagnostic imaging and MR-guided interventions, including hyperthermic ablation of solid cancers. FePt has high Curie temperature, saturation magnetic moment, magneto-crystalline anisotropy, and chemical stability. We describe the synthesis and characterization of a family of biocompatible FePt NPs suitable for biomedical applications, showing and discussing that FePt NPs can exhibit low cytotoxicity. The importance of engineering the interface of strongly magnetic NPs using a coating allowing free aqueous permeation is demonstrated to be an essential parameter in the design of new generations of diagnostic and therapeutic MRI contrast agents. We report effective cell internalization of FePt NPs and demonstrate that they can be used for cellular imaging and in vivo MRI applications. This opens the way for several future applications of FePt NPs, including regenerative medicine and stem cell therapy in addition to enhanced MR diagnostic imaging. PMID:20919679

Power Generation for River and Tidal Generators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muljadi, Eduard; Wright, Alan; Gevorgian, Vahan

Renewable energy sources are the second largest contributor to global electricity production, after fossil fuels. The integration of renewable energy continued to grow in 2014 against a backdrop of increasing global energy consumption and a dramatic decline in oil prices during the second half of the year. As renewable generation has become less expensive during recent decades, and it becomes more accepted by the global population, the focus on renewable generation has expanded from primarily wind and solar to include new types with promising future applications, such as hydropower generation, including river and tidal generation. Today, hydropower is considered onemore » of the most important renewable energy sources. In river and tidal generation, the input resource flow is slower but also steadier than it is in wind or solar generation, yet the level of water turbulent flow may vary from one place to another. This report focuses on hydrokinetic power conversion.« less

Terrestrial Applications of Extreme Environment Stirling Space Power Systems

NASA Technical Reports Server (NTRS)

Dyson, Rodger. W.

2012-01-01

NASA has been developing power systems capable of long-term operation in extreme environments such as the surface of Venus. This technology can use any external heat source to efficiently provide electrical power and cooling; and it is designed to be extremely efficient and reliable for extended space missions. Terrestrial applications include: use in electric hybrid vehicles; distributed home co-generation/cooling; and quiet recreational vehicle power generation. This technology can reduce environmental emissions, petroleum consumption, and noise while eliminating maintenance and environmental damage from automotive fluids such as oil lubricants and air conditioning coolant. This report will provide an overview of this new technology and its applications.

Research and Development of Zinc Air Fuel Cell To Achieve Commercialization Final Report CRADA No. TC-1544-98

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cooper, J. F.; Haley, H. D.

The specific goal of this project was to advance the development of the zinc air fuel cell (ZAFC) towards commercial readiness in different mobile applications, including motor bikes, passenger cars, vans, buses and off-road vehicles (golf carts, factory equipment), and different stationary applications including generator sets, uninterruptible power systems and electric utility loading leveling and distributive power.

U.S. Patent Pending, Cyberspace Security System for Complex Systems, U.S. Patent Application No.: 14/134,949

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abercrombie, Robert K; Sheldon, Frederick T; Mili, Ali

A computer implemented method monetizes the security of a cyber-system in terms of losses each stakeholder may expect to lose if a security break down occurs. A non-transitory media stores instructions for generating a stake structure that includes costs that each stakeholder of a system would lose if the system failed to meet security requirements and generating a requirement structure that includes probabilities of failing requirements when computer components fails. The system generates a vulnerability model that includes probabilities of a component failing given threats materializing and generates a perpetrator model that includes probabilities of threats materializing. The system generatesmore » a dot product of the stakes structure, the requirement structure, the vulnerability model and the perpetrator model. The system can further be used to compare, contrast and evaluate alternative courses of actions best suited for the stakeholders and their requirements.« less

The harmonic state of quantum cascade lasers: origin, control, and prospective applications [Invited].

PubMed

Piccardo, Marco; Chevalier, Paul; Mansuripur, Tobias S; Kazakov, Dmitry; Wang, Yongrui; Rubin, Noah A; Meadowcroft, Lauren; Belyanin, Alexey; Capasso, Federico

2018-04-16

The recently discovered ability of the quantum cascade laser to produce a harmonic frequency comb has attracted new interest in these devices for both applications and fundamental laser physics. In this review we present an extensive experimental phenomenology of the harmonic state, including its appearance in mid-infrared and terahertz quantum cascade lasers, studies of its destabilization induced by delayed optical feedback, and the assessment of its frequency comb nature. A theoretical model explaining its origin as due to the mutual interaction of population gratings and population pulsations inside the laser cavity will be described. We explore different approaches to control the spacing of the harmonic state, such as optical injection seeding and variation of the device temperature. Prospective applications of the harmonic state include microwave and terahertz generation, picosecond pulse generation in the mid-infrared, and broadband spectroscopy.

High-Fidelity Roadway Modeling and Simulation

NASA Technical Reports Server (NTRS)

Wang, Jie; Papelis, Yiannis; Shen, Yuzhong; Unal, Ozhan; Cetin, Mecit

2010-01-01

Roads are an essential feature in our daily lives. With the advances in computing technologies, 2D and 3D road models are employed in many applications, such as computer games and virtual environments. Traditional road models were generated by professional artists manually using modeling software tools such as Maya and 3ds Max. This approach requires both highly specialized and sophisticated skills and massive manual labor. Automatic road generation based on procedural modeling can create road models using specially designed computer algorithms or procedures, reducing the tedious manual editing needed for road modeling dramatically. But most existing procedural modeling methods for road generation put emphasis on the visual effects of the generated roads, not the geometrical and architectural fidelity. This limitation seriously restricts the applicability of the generated road models. To address this problem, this paper proposes a high-fidelity roadway generation method that takes into account road design principles practiced by civil engineering professionals, and as a result, the generated roads can support not only general applications such as games and simulations in which roads are used as 3D assets, but also demanding civil engineering applications, which requires accurate geometrical models of roads. The inputs to the proposed method include road specifications, civil engineering road design rules, terrain information, and surrounding environment. Then the proposed method generates in real time 3D roads that have both high visual and geometrical fidelities. This paper discusses in details the procedures that convert 2D roads specified in shape files into 3D roads and civil engineering road design principles. The proposed method can be used in many applications that have stringent requirements on high precision 3D models, such as driving simulations and road design prototyping. Preliminary results demonstrate the effectiveness of the proposed method.

Natural Language Processing: Toward Large-Scale, Robust Systems.

ERIC Educational Resources Information Center

Haas, Stephanie W.

1996-01-01

Natural language processing (NLP) is concerned with getting computers to do useful things with natural language. Major applications include machine translation, text generation, information retrieval, and natural language interfaces. Reviews important developments since 1987 that have led to advances in NLP; current NLP applications; and problems…

47 CFR 1.743 - Who may sign applications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Complaints, Applications, Tariffs..., including revocation of station license pursuant to section 312(a)(1) of the Communications Act of 1934, as... formed by computer-generated electronic impulses. [28 FR 12450, Nov. 22, 1963, as amended at 53 FR 17193...

47 CFR 1.743 - Who may sign applications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Complaints, Applications, Tariffs..., including revocation of station license pursuant to section 312(a)(1) of the Communications Act of 1934, as... formed by computer-generated electronic impulses. [28 FR 12450, Nov. 22, 1963, as amended at 53 FR 17193...

47 CFR 1.743 - Who may sign applications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Complaints, Applications, Tariffs..., including revocation of station license pursuant to section 312(a)(1) of the Communications Act of 1934, as... formed by computer-generated electronic impulses. [28 FR 12450, Nov. 22, 1963, as amended at 53 FR 17193...

40 CFR 1051.30 - Submission of information.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Submission of information. (a) This part includes various requirements to record data or other information... you send an associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records...

40 CFR 1051.30 - Submission of information.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Submission of information. (a) This part includes various requirements to record data or other information... you send an associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records...

40 CFR 1051.30 - Submission of information.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Submission of information. (a) This part includes various requirements to record data or other information... you send an associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records...

40 CFR 1051.30 - Submission of information.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Submission of information. (a) This part includes various requirements to record data or other information... you send an associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records...

40 CFR 1051.30 - Submission of information.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Submission of information. (a) This part includes various requirements to record data or other information... you send an associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records...

Environment Modeling Using Runtime Values for JPF-Android

NASA Technical Reports Server (NTRS)

van der Merwe, Heila; Tkachuk, Oksana; Nel, Seal; van der Merwe, Brink; Visser, Willem

2015-01-01

Software applications are developed to be executed in a specific environment. This environment includes external native libraries to add functionality to the application and drivers to fire the application execution. For testing and verification, the environment of an application is simplified abstracted using models or stubs. Empty stubs, returning default values, are simple to generate automatically, but they do not perform well when the application expects specific return values. Symbolic execution is used to find input parameters for drivers and return values for library stubs, but it struggles to detect the values of complex objects. In this work-in-progress paper, we explore an approach to generate drivers and stubs based on values collected during runtime instead of using default values. Entry-points and methods that need to be modeled are instrumented to log their parameters and return values. The instrumented applications are then executed using a driver and instrumented libraries. The values collected during runtime are used to generate driver and stub values on- the-fly that improve coverage during verification by enabling the execution of code that previously crashed or was missed. We are implementing this approach to improve the environment model of JPF-Android, our model checking and analysis tool for Android applications.

77 FR 58821 - Alcoa Power Generating Inc.; Notice of Application Accepted for Filing, Soliciting Comments...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-24

... that the period includes about 18 days to draw the reservoir down, maintaining a low stage for about 7... ``MOTION TO INTERVENE'' as applicable; (2) set forth in the heading the name of the applicant and the... 18 CFR 385.2001 through 385.2005. All comments, motions to intervene, or protests must set forth...

ScaMo: Realisation of an OO-functional DSL for cross platform mobile applications development

NASA Astrophysics Data System (ADS)

Macos, Dragan; Solymosi, Andreas

2013-10-01

The software market is dynamically changing: the Internet is going mobile, the software applications are shifting from the desktop hardware onto the mobile devices. The largest markets are the mobile applications for iOS, Android and Windows Phone and for the purpose the typical programming languages include Objective-C, Java and C ♯. The realization of the native applications implies the integration of the developed software into the environments of mentioned mobile operating systems to enable the access to different hardware components of the devices: GPS module, display, GSM module, etc. This paper deals with the definition and possible implementation of an environment for the automatic application generation for multiple mobile platforms. It is based on a DSL for mobile application development, which includes the programming language Scala and a DSL defined in Scala. As part of a multi-stage cross-compiling algorithm, this language is translated into the language of the affected mobile platform. The advantage of our method lies in the expressiveness of the defined language and the transparent source code translation between different languages, which implies, for example, the advantages of debugging and development of the generated code.

Microcombustor-thermoelectric power generator for 10-50 watt applications

NASA Astrophysics Data System (ADS)

Marshall, Daniel S.; Cho, Steve T.

2010-04-01

Fuel-based portable power systems, including combustion and fuel cell systems, take advantage of the 80x higher energy density of fuel over lithium battery technologies and offer the potential for much higher energy density power sources - especially for long-duration applications, such as unattended sensors. Miniaturization of fuel-based systems poses significant challenges, including processing of fuel in small channels, catalyst poisoning, and coke and soot formation. Recent advances in micro-miniature combustors in the 200Watt thermal range have enabled the development of small power sources that use the chemical energy of heavy fuel to drive thermal-to-electric converters for portable applications. CUBE Technology has developed compact Micro-Furnace combustors that efficiently deliver high-quality heat to optimized thermal-to-electric power converters, such as advanced thermoelectric power modules and Stirling motors, for portable power generation at the 10-50Watt scale. Key innovations include a compact gas-gas recuperator, innovative heavy fuel processing, coke- & soot-free operation, and combustor optimization for low balance-of-plant power use while operating at full throttle. This combustor enables the development of robust, high energy density, miniature power sources for portable applications.

Isolated and soft-switched power converter

DOEpatents

Peng, Fang Zheng; Adams, Donald Joe

2002-01-01

An isolated and soft-switched power converter is used for DC/DC and DC/DC/AC power conversion. The power converter includes two resonant tank circuits coupled back-to-back through an isolation transformer. Each resonant tank circuit includes a pair of resonant capacitors connected in series as a resonant leg, a pair of tank capacitors connected in series as a tank leg, and a pair of switching devices with anti-parallel clamping diodes coupled in series as resonant switches and clamping devices for the resonant leg. The power converter is well suited for DC/DC and DC/DC/AC power conversion applications in which high-voltage isolation, DC to DC voltage boost, bidirectional power flow, and a minimal number of conventional switching components are important design objectives. For example, the power converter is especially well suited to electric vehicle applications and load-side electric generation and storage systems, and other applications in which these objectives are important. The power converter may be used for many different applications, including electric vehicles, hybrid combustion/electric vehicles, fuel-cell powered vehicles with low-voltage starting, remote power sources utilizing low-voltage DC power sources, such as photovoltaics and others, electric power backup systems, and load-side electric storage and generation systems.

A novel HTS SMES application in combination with a permanent magnet synchronous generator type wind power generation system

NASA Astrophysics Data System (ADS)

Kim, G. H.; Kim, A. R.; Kim, S.; Park, M.; Yu, I. K.; Seong, K. C.; Won, Y. J.

2011-11-01

Superconducting magnetic energy storage (SMES) system is a DC current driven device and can be utilized to improve power quality particularly in connection with renewable energy sources due to higher efficiency and faster response than other devices. This paper suggests a novel connection topology of SMES which can smoothen the output power flow of the wind power generation system (WPGS). The structure of the proposed system is cost-effective because it reduces a power converter in comparison with a conventional application of SMES. One more advantage of SMES in the proposed system is to improve the capability of low voltage ride through (LVRT) for the permanent magnet synchronous generator (PMSG) type WPGS. The proposed system including a SMES has been modeled and analyzed by a PSCAD/EMTDC. The simulation results show the effectiveness of the novel SMES application strategy to not only mitigate the output power of the PMSG but also improve the capability of LVRT for PMSG type WPGS.

Probe-Directed Degradation (PDD) for Flexible Removal of Unwanted cDNA Sequences from RNA-Seq Libraries.

PubMed

Archer, Stuart K; Shirokikh, Nikolay E; Preiss, Thomas

2015-04-01

Most applications for RNA-seq require the depletion of abundant transcripts to gain greater coverage of the underlying transcriptome. The sequences to be targeted for depletion depend on application and species and in many cases may not be supported by commercial depletion kits. This unit describes a method for generating RNA-seq libraries that incorporates probe-directed degradation (PDD), which can deplete any unwanted sequence set, with the low-bias split-adapter method of library generation (although many other library generation methods are in principle compatible). The overall strategy is suitable for applications requiring customized sequence depletion or where faithful representation of fragment ends and lack of sequence bias is paramount. We provide guidelines to rapidly design specific probes against the target sequence, and a detailed protocol for library generation using the split-adapter method including several strategies for streamlining the technique and reducing adapter dimer content. Copyright © 2015 John Wiley & Sons, Inc.

40 CFR 262.102 - What special definitions are included in this subpart?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Laboratory Waste means a laboratory waste, defined in the Environmental Management Plan as posing significant potential hazards to human health or the environment and which must include RCRA “P” wastes, and may include... (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE University...

Generation of Test Questions from RDF Files Using PYTHON and SPARQL

NASA Astrophysics Data System (ADS)

Omarbekova, Assel; Sharipbay, Altynbek; Barlybaev, Alibek

2017-02-01

This article describes the development of the system for the automatic generation of test questions based on the knowledge base. This work has an applicable nature and provides detailed examples of the development of ontology and implementation the SPARQL queries in RDF-documents. Also it describes implementation of the program generating questions in the Python programming language including the necessary libraries while working with RDF-files.

NIRP Core Software Suite v. 1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whitener, Dustin Heath; Folz, Wesley; Vo, Duong

The NIRP Core Software Suite is a core set of code that supports multiple applications. It includes miscellaneous base code for data objects, mathematic equations, and user interface components; and the framework includes several fully-developed software applications that exist as stand-alone tools to compliment other applications. The stand-alone tools are described below. Analyst Manager: An application to manage contact information for people (analysts) that use the software products. This information is often included in generated reports and may be used to identify the owners of calculations. Radionuclide Viewer: An application for viewing the DCFPAK radiological data. Compliments the Mixture Managermore » tool. Mixture Manager: An application to create and manage radionuclides mixtures that are commonly used in other applications. High Explosive Manager: An application to manage explosives and their properties. Chart Viewer: An application to view charts of data (e.g. meteorology charts). Other applications may use this framework to create charts specific to their data needs.« less

VTT's Fabry-Perot interferometer technologies for hyperspectral imaging and mobile sensing applications

NASA Astrophysics Data System (ADS)

Rissanen, Anna; Guo, Bin; Saari, Heikki; Näsilä, Antti; Mannila, Rami; Akujärvi, Altti; Ojanen, Harri

2017-02-01

VTT's Fabry-Perot interferometers (FPI) technology enables creation of small and cost-efficient microspectrometers and hyperspectral imagers - these robust and light-weight sensors are currently finding their way into a variety of novel applications, including emerging medical products, automotive sensors, space instruments and mobile sensing devices. This presentation gives an overview of our core FPI technologies with current advances in generation of novel sensing applications including recent mobile technology demonstrators of a hyperspectral iPhone and a mobile phone CO2 sensor, which aim to advance mobile spectroscopic sensing.

Ion beam and plasma methods of producing diamondlike carbon films

NASA Technical Reports Server (NTRS)

Swec, Diane M.; Mirtich, Michael J.; Banks, Bruce A.

1988-01-01

A variety of plasma and ion beam techniques was employed to generate diamondlike carbon films. These methods included the use of RF sputtering, dc glow discharge, vacuum arc, plasma gun, ion beam sputtering, and both single and dual ion beam deposition. Since films were generated using a wide variety of techniques, the physico-chemical properties of these films varied considerably. In general, these films had characteristics that were desirable in a number of applications. For example, the films generated using both single and dual ion beam systems were evaluated for applications including power electronics as insulated gates and protective coatings on transmitting windows. These films were impervious to reagents which dissolve graphitic and polymeric carbon structures. Nuclear reaction and combustion analysis indicated hydrogen to carbon ratios to be 1.00, which allowed the films to have good transmittance not only in the infrared, but also in the visible. Other evaluated properties of these films include band gap, resistivity, adherence, density, microhardness, and intrinsic stress. The results of these studies and those of the other techniques for depositing diamondlike carbon films are presented.

76 FR 23230 - Segregation of Lands-Renewable Energy

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-26

... within the wind energy right-of- way application areas in FY 2009 and 2010, we estimate the total cost of... transmission facilities that could be used to carry the power generated from a specific wind or solar energy..., public lands included in a pending or future wind or solar energy generation right-of-way (ROW...

77 FR 67679 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses and Combined Licenses...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-13

... diesel generator surveillance requirements. Margin of safety is related to the ability of the fission... surveillance tests, allowing testing in any MODE of operation. The Division 3 AC sources, including the diesel generator (DG) and its associated emergency loads are accident mitigating features, not accident initiators...

Radioisotope generators for short-lived positron emitters applicable to positron emission tomography

NASA Astrophysics Data System (ADS)

Yano, Y.

1989-04-01

Radioisotope generators provide short-lived positron emitters for positron emission tomography (PET) without the need for an on-site cyclotron. These generators consist of a long-lived parent radionuclide, generally produced on an accelerator, from which the short-lived daughter radionuclide is separated and used as needed. Generators developed and applied to PET studies include 288 d 68Ge for 68 min 68Ga, 25 d 82Sr for 76 s 82Rb and 20.1 h 122Xe for 3.6 min 122I. These radiotracers have been used for the assessment of myocardial and brain blood flow in patient studies. Additionally, 82Rb has been used to determine the breakdown in the blood brain barrier in brain tumor patients who have undergone radiation therapy. When used in conjunction with 18F-fluorodeoxylucose produced on a regional cyclotron for the measurement of glucose utilization in brain tumors, differential diagnosis can be made between tumor regrowth and radiation therapy necrosis. Other possible applications include the detection of vascular lesions with 68Ga labeled platelets or porphyrins.

Novel Bioreactor Platform for Scalable Cardiomyogenic Differentiation from Pluripotent Stem Cell-Derived Embryoid Bodies.

PubMed

Rungarunlert, Sasitorn; Ferreira, Joao N; Dinnyes, Andras

2016-01-01

Generation of cardiomyocytes from pluripotent stem cells (PSCs) is a common and valuable approach to produce large amount of cells for various applications, including assays and models for drug development, cell-based therapies, and tissue engineering. All these applications would benefit from a reliable bioreactor-based methodology to consistently generate homogenous PSC-derived embryoid bodies (EBs) at a large scale, which can further undergo cardiomyogenic differentiation. The goal of this chapter is to describe a scalable method to consistently generate large amount of homogeneous and synchronized EBs from PSCs. This method utilizes a slow-turning lateral vessel bioreactor to direct the EB formation and their subsequent cardiomyogenic lineage differentiation.

Design and economics of a photovoltaic concentrator array for off-grid applications

NASA Astrophysics Data System (ADS)

Maish, A. B.; Rios, M., Jr.

1982-09-01

The array design and expected operation of a photovoltaic concentrator are discussed. A second generation stand alone 680 W/sub p/ photovoltaic (PV) concentrating array for low power, nongrid connected applications was designed. The array consists of six passive cooled point focus Fresnel lens concentrating modules on a two axis polar mount tracking structure. The new array design incorporates several major improvements to the first generation design. These include 50% more array area and a control system which allows unattended, fully automatic operation. The life cycle energy costs are calculated and compared to the equivalent energy costs of a 3 kW diesel electric generator set and an equivalent flat panel PV system.

High-efficiency and flexible generation of vector vortex optical fields by a reflective phase-only spatial light modulator.

PubMed

Cai, Meng-Qiang; Wang, Zhou-Xiang; Liang, Juan; Wang, Yan-Kun; Gao, Xu-Zhen; Li, Yongnan; Tu, Chenghou; Wang, Hui-Tian

2017-08-01

The scheme for generating vector optical fields should have not only high efficiency but also flexibility for satisfying the requirements of various applications. However, in general, high efficiency and flexibility are not compatible. Here we present and experimentally demonstrate a solution to directly, flexibly, and efficiently generate vector vortex optical fields (VVOFs) with a reflective phase-only liquid crystal spatial light modulator (LC-SLM) based on optical birefringence of liquid crystal molecules. To generate the VVOFs, this approach needs in principle only a half-wave plate, an LC-SLM, and a quarter-wave plate. This approach has some advantages, including a simple experimental setup, good flexibility, and high efficiency, making the approach very promising in some applications when higher power is need. This approach has a generation efficiency of 44.0%, which is much higher than the 1.1% of the common path interferometric approach.

Grid-connected in-stream hydroelectric generation based on the doubly fed induction machine

NASA Astrophysics Data System (ADS)

Lenberg, Timothy J.

Within the United States, there is a growing demand for new environmentally friendly power generation. This has led to a surge in wind turbine development. Unfortunately, wind is not a stable prime mover, but water is. Why not apply the advances made for wind to in-stream hydroelectric generation? One important advancement is the creation of the Doubly Fed Induction Machine (DFIM). This thesis covers the application of a gearless DFIM topology for hydrokinetic generation. After providing background, this thesis presents many of the options available for the mechanical portion of the design. A mechanical turbine is then specified. Next, a method is presented for designing a DFIM including the actual design for this application. In Chapter 4, a simulation model of the system is presented, complete with a control system that maximizes power generation based on water speed. This section then goes on to present simulation results demonstrating proper operation.

A Prospectus for the Future Development of a Speech Lab: Hypertext Applications.

ERIC Educational Resources Information Center

Berube, David M.

This paper presents a plan for the next generation of speech laboratories which integrates technologies of modern communication in order to improve and modernize the instructional process. The paper first examines the application of intermediate technologies including audio-video recording and playback, computer assisted instruction and testing…

40 CFR 1033.30 - Submission of information.

Code of Federal Regulations, 2014 CFR

2014-07-01

... information. (a) This part includes various requirements to record data or other information. Refer to § 1033... associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for...

40 CFR 1033.30 - Submission of information.

Code of Federal Regulations, 2011 CFR

2011-07-01

... information. (a) This part includes various requirements to record data or other information. Refer to § 1033... associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for...

40 CFR 1048.30 - Submission of information.

Code of Federal Regulations, 2012 CFR

2012-07-01

... § 1048.30 Submission of information. (a) This part includes various requirements to record data or other... after you send an associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written...

40 CFR 1033.30 - Submission of information.

Code of Federal Regulations, 2012 CFR

2012-07-01

... information. (a) This part includes various requirements to record data or other information. Refer to § 1033... associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for...

40 CFR 1033.30 - Submission of information.

Code of Federal Regulations, 2013 CFR

2013-07-01

... information. (a) This part includes various requirements to record data or other information. Refer to § 1033... associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for...

40 CFR 1048.30 - Submission of information.

Code of Federal Regulations, 2013 CFR

2013-07-01

... § 1048.30 Submission of information. (a) This part includes various requirements to record data or other... after you send an associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written...

40 CFR 1033.30 - Submission of information.

Code of Federal Regulations, 2010 CFR

2010-07-01

... information. (a) This part includes various requirements to record data or other information. Refer to § 1033... associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for...

40 CFR 1048.30 - Submission of information.

Code of Federal Regulations, 2014 CFR

2014-07-01

... § 1048.30 Submission of information. (a) This part includes various requirements to record data or other... after you send an associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written...

40 CFR 1048.30 - Submission of information.

Code of Federal Regulations, 2011 CFR

2011-07-01

... § 1048.30 Submission of information. (a) This part includes various requirements to record data or other... after you send an associated application for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written...

Food Irradiation – Principles and Applications

USDA-ARS?s Scientific Manuscript database

This article deals with the application of ionizing radiation (IR) to foods so as to improve their safety, shelf-life, and quality. The topics covered include: the types of equipment used to generate IR, and their advantages and disadvantages; IR’s mode of action in foods; the latest information on ...

Diffraction radiation generators

NASA Astrophysics Data System (ADS)

Shestopalov, Viktor P.; Vertii, Aleksei A.; Ermak, Gennadii P.; Skrynnik, Boris K.; Khlopov, Grigorii I.; Tsvyk, Aleksei I.

Research in the field of diffraction radiation generators (DRG) conducted at the Radio Physics and electronics Institute of the Ukranian Academy of Sciences over the past 25 years is reviewed. The effect of diffraction radiation is analyzed in detail, and various operating regimes of DRGs are discussed. The discussion then focuses on the principal requirements for the design of packaged DRGs and their principal parameters. Finally, applications of DRGs in various fields of science and technology are reviewed, including such applications as DRG spectroscopy, diagnostics of plasma, biological specimens, and vibration, and DRG radar systems.

Generation of Well-Defined Micro/Nanoparticles via Advanced Manufacturing Techniques for Therapeutic Delivery

PubMed Central

Zhang, Peipei; Xia, Junfei; Luo, Sida

2018-01-01

Micro/nanoparticles have great potentials in biomedical applications, especially for drug delivery. Existing studies identified that major micro/nanoparticle features including size, shape, surface property and component materials play vital roles in their in vitro and in vivo applications. However, a demanding challenge is that most conventional particle synthesis techniques such as emulsion can only generate micro/nanoparticles with a very limited number of shapes (i.e., spherical or rod shapes) and have very loose control in terms of particle sizes. We reviewed the advanced manufacturing techniques for producing micro/nanoparticles with precisely defined characteristics, emphasizing the use of these well-controlled micro/nanoparticles for drug delivery applications. Additionally, to illustrate the vital roles of particle features in therapeutic delivery, we also discussed how the above-mentioned micro/nanoparticle features impact in vitro and in vivo applications. Through this review, we highlighted the unique opportunities in generating controllable particles via advanced manufacturing techniques and the great potential of using these micro/nanoparticles for therapeutic delivery. PMID:29670013

Capabilities needed for the next generation of thermo-hydraulic codes for use in real time applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arndt, S.A.

1997-07-01

The real-time reactor simulation field is currently at a crossroads in terms of the capability to perform real-time analysis using the most sophisticated computer codes. Current generation safety analysis codes are being modified to replace simplified codes that were specifically designed to meet the competing requirement for real-time applications. The next generation of thermo-hydraulic codes will need to have included in their specifications the specific requirement for use in a real-time environment. Use of the codes in real-time applications imposes much stricter requirements on robustness, reliability and repeatability than do design and analysis applications. In addition, the need for codemore » use by a variety of users is a critical issue for real-time users, trainers and emergency planners who currently use real-time simulation, and PRA practitioners who will increasingly use real-time simulation for evaluating PRA success criteria in near real-time to validate PRA results for specific configurations and plant system unavailabilities.« less

High Order Accurate Algorithms for Shocks, Rapidly Changing Solutions and Multiscale Problems

DTIC Science & Technology

2014-11-13

for front propagation with obstacles, and homotopy method for steady states. Applications include high order simulations for 3D gaseous detonations ...obstacles, and homotopy method for steady states. Applications include high order simulations for 3D gaseous detonations , sound generation study via... detonation waves, Combustion and Flame, (02 2013): 0. doi: 10.1016/j.combustflame.2012.10.002 Yang Yang, Ishani Roy, Chi-Wang Shu, Li-Zhi Fang. THE

EDITORIAL: Selected papers from the 11th International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications (PowerMEMS 2011) Selected papers from the 11th International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications (PowerMEMS 2011)

NASA Astrophysics Data System (ADS)

Cho, Young-Ho

2012-09-01

This special section of Journal of Micromechanics and Microengineering features papers selected from the 11th International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications (PowerMEMS 2011), held at Sejong Hotel in Seoul, Korea during 15-18 November 2011. Since the first PowerMEMS workshop held in Sendai, Japan in 2000, the workshop has developed as the premier forum for reporting research results in micro and nanotechnology for power generation, energy conversion, harvesting and processing applications, including in-depth technical issues on nanostructures and materials for small-scale high-density energy and thermal management. Potential PowerMEMS applications cover not only portable power devices for consumer electronics and remote sensors, but also micro engines, impulsive thrusters and fuel cells for systems ranging from the nanometer to the millimeter scale. The 2011 technical program consists of 1 plenary talk, 4 invited talks and 118 contributed presentations. The 48 oral and 70 poster presentations, selected by 27 Technical Program Committee Members from 131 submitted abstracts, have stimulated lively discussion maximizing the interaction between participants. Among them, this special section includes 9 papers covering micro-scale power generators, energy converters, harvesters, thrusters and thermal coolers. Finally, we are grateful to the members of the International Steering Committee, the Technical Program Committee, and the Local Organizing Committee for their efforts and contributions to PowerMEMS 2011. We also thank the two companies Samsung Electro-Mechanics and LG Elite for technical tour arrangements. Special thanks go to Dr Ian Forbes, the editorial staff of the Journal of Micromechanics and Microengineering, as well as to the staff of IOP Publishing for making this special section possible.

Turbine Control of a Tidal and River Power Generator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muljadi, Eduard; Wright, Alan; Gevorgian, Vahan

As renewable generation has become less expensive during recent decades, and it becomes more accepted by the global population, the focus on renewable generation has expanded to include new types with promising future applications, such as river and tidal generation. The input variations to these types of resources are slower but also steadier than wind or solar generation. The level of water turbulent flow may vary from one place to another, however, the control algorithm can be adjusted to local environment. This paper describes the hydrokinetic aspects of river and tidal generation based on a river and tidal generator. Althoughmore » the information given in this paper is not that of an exact generator deployed on site, the data used is representative of a typical river or tidal generator. In this paper, the hydrokinetic and associated electrical controller of the system were not included; however, the focus of this paper is on the hydrodynamic control.« less

Turbine Control of a Tidal and River Power Generator: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muljadi, Eduard; Gevorgian, Vahan; Wright, Alan

As renewable generation has become less expensive during recent decades, and it becomes more accepted by the global population, the focus on renewable generation has expanded to include new types with promising future applications, such as river and tidal generation. The input variations to these types of resources are slower but also steadier than wind or solar generation. The level of water turbulent flow may vary from one place to another, however, the control algorithm can be adjusted to local environment. This paper describes the hydrokinetic aspects of river and tidal generation based on a river and tidal generator. Althoughmore » the information given in this paper is not that of an exact generator deployed on site, the data used is representative of a typical river or tidal generator. In this paper, the hydrokinetic and associated electrical controller of the system were not included; however, the focus of this paper is on the hydrodynamic control.« less

Yttrium-90 -- current status, expected availability and applications of a high beta energy emitter.

PubMed

Montaña, R Leyva; González, I Hernández; Ramirez, A Alberti; Garaboldi, L; Chinol, M

2012-07-01

Yttrium-90 ((90)Y, T(1/2) 64.14 h) is a key example of a high beta energy-emitting radionuclide which is available from the strontium-90 ((90)Sr)/(90)Y radionuclide generator system. Clinical uses of (90)Y-labeled radiopharmaceutical agents have been pursued for many years and many applications have proven to be clinical effective. These most notably include the application of 90Y-labeled antibodies for a variety of applications such as for effective treatment of non-Hodgkin's lymphoma. One of the major advantages for use of (90)Y is ready availability from the very long-lived (90)Sr parent (T(1/2) 28.78 y). Because of the importance of maintaining generator performance and minimizing parent breakthrough, this paper describes development, use and quality control of both high capacity cation adsorption-type and electrochemical generator systems. In addition, the preparation and targeting to tumors in mice of DOTA-conjugated Nimotuzamab (h-R3) antibody which recognizes the external domain of the EPFR antibody radiolabeled with (90)Y obtained from the electrochemical generator is also described. As a key example for clinical applications of (90)Y, the use of (90)Y-labeled biotin for intra-operative pre-targeting for radionuclide therapy (IART®) of breast cancer is also described.

The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button

PubMed Central

2010-01-01

Background There is a huge demand on bioinformaticians to provide their biologists with user friendly and scalable software infrastructures to capture, exchange, and exploit the unprecedented amounts of new *omics data. We here present MOLGENIS, a generic, open source, software toolkit to quickly produce the bespoke MOLecular GENetics Information Systems needed. Methods The MOLGENIS toolkit provides bioinformaticians with a simple language to model biological data structures and user interfaces. At the push of a button, MOLGENIS’ generator suite automatically translates these models into a feature-rich, ready-to-use web application including database, user interfaces, exchange formats, and scriptable interfaces. Each generator is a template of SQL, JAVA, R, or HTML code that would require much effort to write by hand. This ‘model-driven’ method ensures reuse of best practices and improves quality because the modeling language and generators are shared between all MOLGENIS applications, so that errors are found quickly and improvements are shared easily by a re-generation. A plug-in mechanism ensures that both the generator suite and generated product can be customized just as much as hand-written software. Results In recent years we have successfully evaluated the MOLGENIS toolkit for the rapid prototyping of many types of biomedical applications, including next-generation sequencing, GWAS, QTL, proteomics and biobanking. Writing 500 lines of model XML typically replaces 15,000 lines of hand-written programming code, which allows for quick adaptation if the information system is not yet to the biologist’s satisfaction. Each application generated with MOLGENIS comes with an optimized database back-end, user interfaces for biologists to manage and exploit their data, programming interfaces for bioinformaticians to script analysis tools in R, Java, SOAP, REST/JSON and RDF, a tab-delimited file format to ease upload and exchange of data, and detailed technical documentation. Existing databases can be quickly enhanced with MOLGENIS generated interfaces using the ‘ExtractModel’ procedure. Conclusions The MOLGENIS toolkit provides bioinformaticians with a simple model to quickly generate flexible web platforms for all possible genomic, molecular and phenotypic experiments with a richness of interfaces not provided by other tools. All the software and manuals are available free as LGPLv3 open source at http://www.molgenis.org. PMID:21210979

Physics and applications of atmospheric nonlinear optics and filamentation.

PubMed

Kasparian, Jérôme; Wolf, Jean-Pierre

2008-01-07

We review the properties and applications of ultrashort laser pulses in the atmosphere, with a particular focus on filamentation. Filamentation is a non-linear propagation regime specific of ultrashort and ultraintense laser pulses in the atmosphere. Typical applications include remote sensing of atmospheric gases and aerosols, lightning control, laser-induced spectroscopy, coherent anti-stokes Raman scattering, and the generation of sub-THz radiation.

Automatic Generation of Cycle-Approximate TLMs with Timed RTOS Model Support

NASA Astrophysics Data System (ADS)

Hwang, Yonghyun; Schirner, Gunar; Abdi, Samar

This paper presents a technique for automatically generating cycle-approximate transaction level models (TLMs) for multi-process applications mapped to embedded platforms. It incorporates three key features: (a) basic block level timing annotation, (b) RTOS model integration, and (c) RTOS overhead delay modeling. The inputs to TLM generation are application C processes and their mapping to processors in the platform. A processor data model, including pipelined datapath, memory hierarchy and branch delay model is used to estimate basic block execution delays. The delays are annotated to the C code, which is then integrated with a generated SystemC RTOS model. Our abstract RTOS provides dynamic scheduling and inter-process communication (IPC) with processor- and RTOS-specific pre-characterized timing. Our experiments using a MP3 decoder and a JPEG encoder show that timed TLMs, with integrated RTOS models, can be automatically generated in less than a minute. Our generated TLMs simulated three times faster than real-time and showed less than 10% timing error compared to board measurements.

Transformative Advances in DDDAS with Application to Space Weather Monitoring

DTIC Science & Technology

2015-10-01

subsystems, including power and communications subsystems. In addition, a study of photovoltaic power generation constraints due to spacecraft solar...estimation. Automatica, 23:775–778, 1987. [61] D. Y. Lee, J. W. Cutler, J. Mancewicz, and A. J. Ridley. Maximizing photovoltaic power generation of a space...Maximizing photovoltaic power generation of a space-dart configured satellite. Acta Astronautica, 111:283–299, 2015. A. V. Morozov, A. J. Ridley, D. S

Bio optofluidics cell sorter: cell-BOCS concept and applications

NASA Astrophysics Data System (ADS)

Roth, Tue; Glückstad, Jesper

2012-03-01

The cell-BOCS is a novel microfluidics based cell-sorting instrument utilizing next generation optical trapping technology developed at the Technical University of Denmark. It is targeted emerging bio-medical research and diagnostics markets where it for certain applications offers a number of advantages over conventional fluorescence activated cell-sorting (FACSTM) technology. Advantages include gentle handling of cells, sterile sorting, easy operation, small footprint and lower cost allowing out-of-core-facility use. Application examples are found within sorting of fragile transfected cells, high value samples and primary cell lines, where traditional FACS technology has limited application due to it's droplet-based approach to cell-sorting. In the diagnostics field, in particular applying the cell-BOCS for isolating pure populations of circulating tumor cells is an area that has generated a lot of interest.

ACPYPE - AnteChamber PYthon Parser interfacE.

PubMed

Sousa da Silva, Alan W; Vranken, Wim F

2012-07-23

ACPYPE (or AnteChamber PYthon Parser interfacE) is a wrapper script around the ANTECHAMBER software that simplifies the generation of small molecule topologies and parameters for a variety of molecular dynamics programmes like GROMACS, CHARMM and CNS. It is written in the Python programming language and was developed as a tool for interfacing with other Python based applications such as the CCPN software suite (for NMR data analysis) and ARIA (for structure calculations from NMR data). ACPYPE is open source code, under GNU GPL v3, and is available as a stand-alone application at http://www.ccpn.ac.uk/acpype and as a web portal application at http://webapps.ccpn.ac.uk/acpype. We verified the topologies generated by ACPYPE in three ways: by comparing with default AMBER topologies for standard amino acids; by generating and verifying topologies for a large set of ligands from the PDB; and by recalculating the structures for 5 protein-ligand complexes from the PDB. ACPYPE is a tool that simplifies the automatic generation of topology and parameters in different formats for different molecular mechanics programmes, including calculation of partial charges, while being object oriented for integration with other applications.

Probabilistic wind/tornado/missile analyses for hazard and fragility evaluations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Y.J.; Reich, M.

Detailed analysis procedures and examples are presented for the probabilistic evaluation of hazard and fragility against high wind, tornado, and tornado-generated missiles. In the tornado hazard analysis, existing risk models are modified to incorporate various uncertainties including modeling errors. A significant feature of this paper is the detailed description of the Monte-Carlo simulation analyses of tornado-generated missiles. A simulation procedure, which includes the wind field modeling, missile injection, solution of flight equations, and missile impact analysis, is described with application examples.

ESAS Deliverable PS 1.1.2.3: Customer Survey on Code Generations in Safety-Critical Applications

NASA Technical Reports Server (NTRS)

Schumann, Johann; Denney, Ewen

2006-01-01

Automated code generators (ACG) are tools that convert a (higher-level) model of a software (sub-)system into executable code without the necessity for a developer to actually implement the code. Although both commercially supported and in-house tools have been used in many industrial applications, little data exists on how these tools are used in safety-critical domains (e.g., spacecraft, aircraft, automotive, nuclear). The aims of the survey, therefore, were threefold: 1) to determine if code generation is primarily used as a tool for prototyping, including design exploration and simulation, or for fiight/production code; 2) to determine the verification issues with code generators relating, in particular, to qualification and certification in safety-critical domains; and 3) to determine perceived gaps in functionality of existing tools.

76 FR 4097 - Verdant Power, LLC (Verdant); Notice of Application Tendered for Filing With the Commission and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-24

... facilities would include: (1) Three 35-kilowatt (kW), 5-meter-diameter axial flow Kinetic System turbine...; (2) nine additional 5-meter-diameter axial flow Kinetic System turbine generator units mounted on...-meter-diameter axial flow Kinetic System turbine generator units mounted on six triframe mounts, with a...

Perception and Practice of Taiwanese EFL Learners' Making Vocabulary Flashcards on "Quizlet"

ERIC Educational Resources Information Center

Chien, Chin-Wen

2013-01-01

The new generation is digital natives and they enjoy using the latest technology such as online resources, mobile phones, and applications. Linking technology and English learning can be an alternative to motivate the new generation to learn English. The participants in this study included 76 freshmen in a university in Taiwan. The major data in…

Transparent, Flexible Silicon Nanostructured Wire Networks with Seamless Junctions for High-Performance Photodetector Applications.

PubMed

Hossain, Mozakkar; Kumar, Gundam Sandeep; Barimar Prabhava, S N; Sheerin, Emmet D; McCloskey, David; Acharya, Somobrata; Rao, K D M; Boland, John J

2018-05-22

Optically transparent photodetectors are crucial in next-generation optoelectronic applications including smart windows and transparent image sensors. Designing photodetectors with high transparency, photoresponsivity, and robust mechanical flexibility remains a significant challenge, as is managing the inevitable trade-off between high transparency and strong photoresponse. Here we report a scalable method to produce flexible crystalline Si nanostructured wire (NW) networks fabricated from silicon-on-insulator (SOI) with seamless junctions and highly responsive porous Si segments that combine to deliver exceptional performance. These networks show high transparency (∼92% at 550 nm), broadband photodetection (350 to 950 nm) with excellent responsivity (25 A/W), optical response time (0.58 ms), and mechanical flexibility (1000 cycles). Temperature-dependent photocurrent measurements indicate the presence of localized electronic states in the porous Si segments, which play a crucial role in light harvesting and photocarrier generation. The scalable low-cost approach based on SOI has the potential to deliver new classes of flexible optoelectronic devices, including next-generation photodetectors and solar cells.

Bioactive peptides from meat muscle and by-products: generation, functionality and application as functional ingredients.

PubMed

Lafarga, Tomas; Hayes, Maria

2014-10-01

Bioactive peptides are sequences of between 2-30 amino acids in length that impart a positive health effect to the consumer when ingested. They have been identified from a range of foods, including milk and muscle sources including beef, chicken, pork and marine muscles. The myriad of peptides identified from these sources have known antihypertensive, opioid, antioxidant, antithrombotic and other bioactivities. Indeed, bioactive peptides could play a role in the prevention of diseases associated with the development of metabolic syndrome and mental health diseases. The aim of this work is to present an overview of the bioactive peptides identified in muscle proteins and by-products generated during the processing of meat. The paper looks at the isolation, enrichment and characterisation strategies that have been employed to date to generate bioactive peptides and the potential future applications of these peptides in functional foods for the prevention of heart and mental health problems and obesity. Copyright © 2014 Elsevier Ltd. All rights reserved.

Evaluation of grid generation technologies from an applied perspective

NASA Technical Reports Server (NTRS)

Hufford, Gary S.; Harrand, Vincent J.; Patel, Bhavin C.; Mitchell, Curtis R.

1995-01-01

An analysis of the grid generation process from the point of view of an applied CFD engineer is given. Issues addressed include geometric modeling, structured grid generation, unstructured grid generation, hybrid grid generation and use of virtual parts libraries in large parametric analysis projects. The analysis is geared towards comparing the effective turn around time for specific grid generation and CFD projects. The conclusion was made that a single grid generation methodology is not universally suited for all CFD applications due to both limitations in grid generation and flow solver technology. A new geometric modeling and grid generation tool, CFD-GEOM, is introduced to effectively integrate the geometric modeling process to the various grid generation methodologies including structured, unstructured, and hybrid procedures. The full integration of the geometric modeling and grid generation allows implementation of extremely efficient updating procedures, a necessary requirement for large parametric analysis projects. The concept of using virtual parts libraries in conjunction with hybrid grids for large parametric analysis projects is also introduced to improve the efficiency of the applied CFD engineer.

34 CFR 645.21 - What assurances must an applicant include in an application?

Code of Federal Regulations, 2014 CFR

2014-07-01

... the project's participants will be low-income individuals who are potential first-generation college... participation in a project because the student would enter the project after the 9th grade; and (4) The project will collaborate with other Federal TRIO projects, GEAR UP projects, or programs serving similar...

34 CFR 645.21 - What assurances must an applicant include in an application?

Code of Federal Regulations, 2012 CFR

2012-07-01

... the project's participants will be low-income individuals who are potential first-generation college... participation in a project because the student would enter the project after the 9th grade; and (4) The project will collaborate with other Federal TRIO projects, GEAR UP projects, or programs serving similar...

34 CFR 645.21 - What assurances must an applicant include in an application?

Code of Federal Regulations, 2013 CFR

2013-07-01

... the project's participants will be low-income individuals who are potential first-generation college... participation in a project because the student would enter the project after the 9th grade; and (4) The project will collaborate with other Federal TRIO projects, GEAR UP projects, or programs serving similar...

40 CFR 1054.30 - Submission of information.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Applicability § 1054.30 Submission of information. (a) This part includes various requirements to record data or... after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review them at any time. (b...

40 CFR 1060.30 - Submission of information.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Applicability § 1060.30 Submission of information. (a) This part includes various requirements to record data or... for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review...

40 CFR 1054.30 - Submission of information.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Applicability § 1054.30 Submission of information. (a) This part includes various requirements to record data or... after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review them at any time. (b...

40 CFR 1039.30 - Submission of information.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Applicability § 1039.30 Submission of information. (a) This part includes various requirements to record data or... generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review them at any time. (b) The...

40 CFR 1039.30 - Submission of information.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Applicability § 1039.30 Submission of information. (a) This part includes various requirements to record data or... generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review them at any time. (b) The...

40 CFR 1054.30 - Submission of information.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Applicability § 1054.30 Submission of information. (a) This part includes various requirements to record data or... after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review them at any time. (b...

40 CFR 1054.30 - Submission of information.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Applicability § 1054.30 Submission of information. (a) This part includes various requirements to record data or... after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review them at any time. (b...

40 CFR 1039.30 - Submission of information.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Applicability § 1039.30 Submission of information. (a) This part includes various requirements to record data or... generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review them at any time. (b) The...

40 CFR 1060.30 - Submission of information.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Applicability § 1060.30 Submission of information. (a) This part includes various requirements to record data or... for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review...

40 CFR 1039.30 - Submission of information.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Applicability § 1039.30 Submission of information. (a) This part includes various requirements to record data or... generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review them at any time. (b) The...

40 CFR 1060.30 - Submission of information.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Applicability § 1060.30 Submission of information. (a) This part includes various requirements to record data or... for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review...

40 CFR 1060.30 - Submission of information.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Applicability § 1060.30 Submission of information. (a) This part includes various requirements to record data or... for certification, or one year after you generate the data if they do not support an application for certification. You must promptly send us organized, written records in English if we ask for them. We may review...

National Aerospace Leadership Initiative - Phase 2

DTIC Science & Technology

2010-03-01

components) for turbine airfoils and larger sized components (e.g., combustor, augmenter, and nozzle applications). Substrate material properties ...material property impact to sensing, measurement and breakthrough detection. Establishment of CCAT’s Laser Applications Laboratory that includes next...generation and materials property (and component) validation. Task IV - Total Supply Chain Enterprise Effectiveness The competitiveness and

Resources in the VLab Science Gateway: Online applications for thermodynamics and thermal elastic properties of mantle minerals

NASA Astrophysics Data System (ADS)

Wentzcovitch, R. M.; Da Silveira, P. R.; Wu, Z.; Yu, Y.

2013-12-01

Today first principles calculations in mineral physics play a fundamental role in understanding of the Earth. They complement experiments by expanding the pressure and temperature range for which properties can be obtained and provide access to atomic scale phenomena. Since the wealth of predictive first principles results can hardly be communicated in printed form, we have developed online applications where published results can be reproduced/verified online and extensive unpublished results can be generated in customized form. So far these applications have included thermodynamics properties of end-member phases and thermal elastic properties of end-member phases and few solid solutions. Extension of this software infrastructure to include other properties is in principle straightforward. This contribution will review the nature of results that can be generated (methods, thermodynamics domain, list of minerals, properties, etc) and nature of the software infrastructure. These applications are part of a more extensive cyber-infrastructure operating in the XSEDE - the VLab Science Gateway [1]. [1] https://www.xsede.org/web/guest/gateways-listing Research supported by NSF grants ATM-0428744 and EAR-1047629.

Detailed Modeling of Physical Processes in Electron Sources for Accelerator Applications

NASA Astrophysics Data System (ADS)

Chubenko, Oksana; Afanasev, Andrei

2017-01-01

At present, electron sources are essential in a wide range of applications - from common technical use to exploring the nature of matter. Depending on the application requirements, different methods and materials are used to generate electrons. State-of-the-art accelerator applications set a number of often-conflicting requirements for electron sources (e.g., quantum efficiency vs. polarization, current density vs. lifetime, etc). Development of advanced electron sources includes modeling and design of cathodes, material growth, fabrication of cathodes, and cathode testing. The detailed simulation and modeling of physical processes is required in order to shed light on the exact mechanisms of electron emission and to develop new-generation electron sources with optimized efficiency. The purpose of the present work is to study physical processes in advanced electron sources and develop scientific tools, which could be used to predict electron emission from novel nano-structured materials. In particular, the area of interest includes bulk/superlattice gallium arsenide (bulk/SL GaAs) photo-emitters and nitrogen-incorporated ultrananocrystalline diamond ((N)UNCD) photo/field-emitters. Work supported by The George Washington University and Euclid TechLabs LLC.

CRISPR-Based Technologies and the Future of Food Science.

PubMed

Selle, Kurt; Barrangou, Rodolphe

2015-11-01

The on-going CRISPR craze is focused on the use of Cas9-based technologies for genome editing applications in eukaryotes, with high potential for translational medicine and next-generation gene therapy. Nevertheless, CRISPR-Cas systems actually provide adaptive immunity in bacteria, and have much promise for various applications in food bacteria that include high-resolution typing of pathogens, vaccination of starter cultures against phages, and the genesis of programmable and specific antibiotics that can selectively modulate bacterial population composition. Indeed, the molecular machinery from these DNA-encoded, RNA-mediated, DNA-targeting systems can be harnessed in native hosts, or repurposed in engineered systems for a plethora of applications that can be implemented in all organisms relevant to the food chain, including agricultural crops trait-enhancement, livestock breeding, and fermentation-based manufacturing, and for the genesis of next-generation food products with enhanced quality and health-promoting functionalities. CRISPR-based applications are now poised to revolutionize many fields within food science, from farm to fork. In this review, we describe CRISPR-Cas systems and highlight their potential for the development of enhanced foods. © 2015 Institute of Food Technologists®

High Efficiency Particulate Air (HEPA) Filter Generation, Characterization, and Disposal Experiences at the Oak Ridge National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coffey, D. E.

2002-02-28

High Efficiency Particulate Air filtration is an essential component of the containment and ventilation systems supporting the research and development activities at the Oak Ridge National Laboratory. High Efficiency Particulate Air filters range in size from 7.6cm (3 inch) by 10.2 cm (4 inch) cylindrical shape filters to filter array assemblies up to 2.1 m (7 feet) high by 1.5 m (5 feet) wide. Spent filters are grouped by contaminates trapped in the filter media and become one of the components in the respective waste stream. Waste minimization and pollution prevention efforts are applied for both radiological and non-radiological applications.more » Radiological applications include laboratory hoods, glove boxes, and hot cells. High Efficiency Particulate Air filters also are generated from intake or pre-filtering applications, decontamination activities, and asbestos abatement applications. The disposal avenues include sanitary/industrial waste, Resource Conservation and Recovery Act and Toxic Substance Control Act, regulated waste, solid low-level waste, contact handled transuranic, and remote handled transuranic waste. This paper discusses characterization and operational experiences associated with the disposal of the spent filters across multiple applications.« less

Generating Safety-Critical PLC Code From a High-Level Application Software Specification

NASA Technical Reports Server (NTRS)

2008-01-01

The benefits of automatic-application code generation are widely accepted within the software engineering community. These benefits include raised abstraction level of application programming, shorter product development time, lower maintenance costs, and increased code quality and consistency. Surprisingly, code generation concepts have not yet found wide acceptance and use in the field of programmable logic controller (PLC) software development. Software engineers at Kennedy Space Center recognized the need for PLC code generation while developing the new ground checkout and launch processing system, called the Launch Control System (LCS). Engineers developed a process and a prototype software tool that automatically translates a high-level representation or specification of application software into ladder logic that executes on a PLC. All the computer hardware in the LCS is planned to be commercial off the shelf (COTS), including industrial controllers or PLCs that are connected to the sensors and end items out in the field. Most of the software in LCS is also planned to be COTS, with only small adapter software modules that must be developed in order to interface between the various COTS software products. A domain-specific language (DSL) is a programming language designed to perform tasks and to solve problems in a particular domain, such as ground processing of launch vehicles. The LCS engineers created a DSL for developing test sequences of ground checkout and launch operations of future launch vehicle and spacecraft elements, and they are developing a tabular specification format that uses the DSL keywords and functions familiar to the ground and flight system users. The tabular specification format, or tabular spec, allows most ground and flight system users to document how the application software is intended to function and requires little or no software programming knowledge or experience. A small sample from a prototype tabular spec application is shown.

Solid polymer electrolyte water electrolysis system development. [to generate oxygen for manned space station applications

NASA Technical Reports Server (NTRS)

1975-01-01

Solid polymer electrolyte technology used in a water electrolysis system (WES) to generate oxygen and hydrogen for manned space station applications was investigated. A four-man rated, low pressure breadboard water electrolysis system with the necessary instrumentation and controls was fabricated and tested. A six man rated, high pressure, high temperature, advanced preprototype WES was developed. This configuration included the design and development of an advanced water electrolysis module, capable of operation at 400 psig and 200 F, and a dynamic phase separator/pump in place of a passive phase separator design. Evaluation of this system demonstrated the goal of safe, unattended automated operation at high pressure and high temperature with an accumulated gas generation time of over 1000 hours.

Task 6 -- Advanced turbine systems program conceptual design and product development

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-01-10

The Allison Engine Company has completed the Task 6 Conceptual Design and Analysis of Phase 2 of the Advanced Turbine System (ATS) contract. At the heart of Allison`s system is an advanced simple cycle gas turbine engine. This engine will incorporate components that ensure the program goals are met. Allison plans to commercialize the ATS demonstrator and market a family of engines incorporating this technology. This family of engines, ranging from 4.9 MW to 12 MW, will be suitable for use in all industrial engine applications, including electric power generation, mechanical drive, and marine propulsion. In the field of electricmore » power generation, the engines will be used for base load, standby, cogeneration, and distributed generation applications.« less

Kaman 40 kW wind turbine generator - control system dynamics

NASA Technical Reports Server (NTRS)

Perley, R.

1981-01-01

The generator design incorporates an induction generator for application where a utility line is present and a synchronous generator for standalone applications. A combination of feed forward and feedback control is used to achieve synchronous speed prior to connecting the generator to the load, and to control the power level once the generator is connected. The dynamics of the drive train affect several aspects of the system operation. These were analyzed to arrive at the required shaft stiffness. The rotor parameters that affect the stability of the feedback control loop vary considerably over the wind speed range encountered. Therefore, the controller gain was made a function of wind speed in order to maintain consistent operation over the whole wind speed range. The velocity requirement for the pitch control mechanism is related to the nature of the wind gusts to be encountered, the dynamics of the system, and the acceptable power fluctuations and generator dropout rate. A model was developed that allows the probable dropout rate to be determined from a statistical model of wind gusts and the various system parameters, including the acceptable power fluctuation.

Apparatus for millimeter-wave signal generation

DOEpatents

Vawter, G. Allen; Hietala, Vincent M.; Zolper, John C.; Mar, Alan; Hohimer, John P.

1999-01-01

An opto-electronic integrated circuit (OEIC) apparatus is disclosed for generating an electrical signal at a frequency .gtoreq.10 GHz. The apparatus, formed on a single substrate, includes a semiconductor ring laser for generating a continuous train of mode-locked lasing pulses and a high-speed photodetector for detecting the train of lasing pulses and generating the electrical signal therefrom. Embodiments of the invention are disclosed with an active waveguide amplifier coupling the semiconductor ring laser and the high-speed photodetector. The invention has applications for use in OEICs and millimeter-wave monolithic integrated circuits (MMICs).

A Data Warehouse to Support Condition Based Maintenance (CBM)

DTIC Science & Technology

2005-05-01

Application ( VBA ) code sequence to import the original MAST-generated CSV and then create a single output table in DBASE IV format. The DBASE IV format...database architecture (Oracle, Sybase, MS- SQL , etc). This design includes table definitions, comments, specification of table attributes, primary and foreign...built queries and applications. Needs the application developers to construct data views. No SQL programming experience. b. Power Database User - knows

Novel Space-based Solar Power Technologies and Architectures for Earth and Beyond

NASA Technical Reports Server (NTRS)

Howell, Joe T.; Fikes, John C.; O'Neill, Mark J.

2005-01-01

Research, development and studies of novel space-based solar power systems, technologies and architectures for Earth and beyond are needed to reduce the cost of clean electrical power for terrestrial use and to provide a stepping stone for providing an abundance of power in space, i.e., manufacturing facilities, tourist facilities, delivery of power between objects in space, and between space and surface sites. The architectures, technologies and systems needed for space to Earth applications may also be used for in-space applications. Advances in key technologies, i.e., power generation, power management and distribution, power beaming and conversion of beamed power are needed to achieve the objectives of both terrestrial and extraterrestrial applications. Power beaming or wireless power transmission (WPT) can involve lasers or microwaves along with the associated power interfaces. Microwave and laser transmission techniques have been studied with several promising approaches to safe and efficient WPT identified. These investigations have included microwave phased array transmitters, as well as laser transmission and associated optics. There is a need to produce "proof-of-concept" validation of critical WPT technologies for both the near-term, as well as far-term applications. Investments may be harvested in near-term beam safe demonstrations of commercial WPT applications. Receiving sites (users) include ground-based stations for terrestrial electrical power, orbital sites to provide power for satellites and other platforms, future space elevator systems, space vehicle propulsion, and space to surface sites. This paper briefly discusses achieving a promising approach to the solar power generation and beamed power conversion. The approach is based on a unique high-power solar concentrator array called Stretched Lens Array (SLA) for both solar power generation and beamed power conversion. Since both versions (solar and laser) of SLA use many identical components (only the photovoltaic cells need to be different), economies of manufacturing and scale may be realized by using SLA on both ends of the laser power beaming system in a space solar power application. Near-term uses of this SLA-laser-SLA system may include terrestrial and space exploration in near Earth space. Later uses may include beamed power for bases or vehicles on Mars.

Onboard Plasmatron Hydrogen Production for Improved Vehicles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daniel R. Cohn; Leslie Bromberg; Kamal Hadidi

2005-12-31

A plasmatron fuel reformer has been developed for onboard hydrogen generation for vehicular applications. These applications include hydrogen addition to spark-ignition internal combustion engines, NOx trap and diesel particulate filter (DPF) regeneration, and emissions reduction from spark ignition internal combustion engines First, a thermal plasmatron fuel reformer was developed. This plasmatron used an electric arc with relatively high power to reform fuels such as gasoline, diesel and biofuels at an oxygen to carbon ratio close to 1. The draw back of this device was that it has a high electric consumption and limited electrode lifetime due to the high temperaturemore » electric arc. A second generation plasmatron fuel reformer was developed. It used a low-current high-voltage electric discharge with a completely new electrode continuation. This design uses two cylindrical electrodes with a rotating discharge that produced low temperature volumetric cold plasma., The lifetime of the electrodes was no longer an issue and the device was tested on several fuels such as gasoline, diesel, and biofuels at different flow rates and different oxygen to carbon ratios. Hydrogen concentration and yields were measured for both the thermal and non-thermal plasmatron reformers for homogeneous (non-catalytic) and catalytic reforming of several fuels. The technology was licensed to an industrial auto part supplier (ArvinMeritor) and is being implemented for some of the applications listed above. The Plasmatron reformer has been successfully tested on a bus for NOx trap regeneration. The successful development of the plasmatron reformer and its implementation in commercial applications including transportation will bring several benefits to the nation. These benefits include the reduction of NOx emissions, improving engine efficiency and reducing the nation's oil consumption. The objective of this program has been to develop attractive applications of plasmatron fuel reformer technology for onboard applications in internal combustion engine vehicles using diesel, gasoline and biofuels. This included the reduction of NOx and particulate matter emissions from diesel engines using plasmatron reformer generated hydrogen-rich gas, conversion of ethanol and bio-oils into hydrogen rich gas, and the development of new concepts for the use of plasmatron fuel reformers for enablement of HCCI engines.« less

Application-specific coarse-grained reconfigurable array: architecture and design methodology

NASA Astrophysics Data System (ADS)

Zhou, Li; Liu, Dongpei; Zhang, Jianfeng; Liu, Hengzhu

2015-06-01

Coarse-grained reconfigurable arrays (CGRAs) have shown potential for application in embedded systems in recent years. Numerous reconfigurable processing elements (PEs) in CGRAs provide flexibility while maintaining high performance by exploring different levels of parallelism. However, a difference remains between the CGRA and the application-specific integrated circuit (ASIC). Some application domains, such as software-defined radios (SDRs), require flexibility with performance demand increases. More effective CGRA architectures are expected to be developed. Customisation of a CGRA according to its application can improve performance and efficiency. This study proposes an application-specific CGRA architecture template composed of generic PEs (GPEs) and special PEs (SPEs). The hardware of the SPE can be customised to accelerate specific computational patterns. An automatic design methodology that includes pattern identification and application-specific function unit generation is also presented. A mapping algorithm based on ant colony optimisation is provided. Experimental results on the SDR target domain show that compared with other ordinary and application-specific reconfigurable architectures, the CGRA generated by the proposed method performs more efficiently for given applications.

Advanced software development workstation. Knowledge base design: Design of knowledge base for flight planning application

NASA Technical Reports Server (NTRS)

Izygon, Michel E.

1992-01-01

The development process of the knowledge base for the generation of Test Libraries for Mission Operations Computer (MOC) Command Support focused on a series of information gathering interviews. These knowledge capture sessions are supporting the development of a prototype for evaluating the capabilities of INTUIT on such an application. the prototype includes functions related to POCC (Payload Operation Control Center) processing. It prompts the end-users for input through a series of panels and then generates the Meds associated with the initialization and the update of hazardous command tables for a POCC Processing TLIB.

Safe Life Propulsion Design Technologies (3rd Generation Propulsion Research and Technology)

NASA Technical Reports Server (NTRS)

Ellis, Rod

2000-01-01

The tasks outlined in this viewgraph presentation on safe life propulsion design technologies (third generation propulsion research and technology) include the following: (1) Ceramic matrix composite (CMC) life prediction methods; (2) Life prediction methods for ultra high temperature polymer matrix composites for reusable launch vehicle (RLV) airframe and engine application; (3) Enabling design and life prediction technology for cost effective large-scale utilization of MMCs and innovative metallic material concepts; (4) Probabilistic analysis methods for brittle materials and structures; (5) Damage assessment in CMC propulsion components using nondestructive characterization techniques; and (6) High temperature structural seals for RLV applications.

Plasma dye coating as straightforward and widely applicable procedure for dye immobilization on polymeric materials.

PubMed

De Smet, Lieselot; Vancoillie, Gertjan; Minshall, Peter; Lava, Kathleen; Steyaert, Iline; Schoolaert, Ella; Van De Walle, Elke; Dubruel, Peter; De Clerck, Karen; Hoogenboom, Richard

2018-03-16

Here, we introduce a novel concept for the fabrication of colored materials with significantly reduced dye leaching through covalent immobilization of the desired dye using plasma-generated surface radicals. This plasma dye coating (PDC) procedure immobilizes a pre-adsorbed layer of a dye functionalized with a radical sensitive group on the surface through radical addition caused by a short plasma treatment. The non-specific nature of the plasma-generated surface radicals allows for a wide variety of dyes including azobenzenes and sulfonphthaleins, functionalized with radical sensitive groups to avoid significant dye degradation, to be combined with various materials including PP, PE, PA6, cellulose, and PTFE. The wide applicability, low consumption of dye, relatively short procedure time, and the possibility of continuous PDC using an atmospheric plasma reactor make this procedure economically interesting for various applications ranging from simple coloring of a material to the fabrication of chromic sensor fabrics as demonstrated by preparing a range of halochromic materials.

[The principle and application of the single-molecule real-time sequencing technology].

PubMed

Yanhu, Liu; Lu, Wang; Li, Yu

2015-03-01

Last decade witnessed the explosive development of the third-generation sequencing strategy, including single-molecule real-time sequencing (SMRT), true single-molecule sequencing (tSMSTM) and the single-molecule nanopore DNA sequencing. In this review, we summarize the principle, performance and application of the SMRT sequencing technology. Compared with the traditional Sanger method and the next-generation sequencing (NGS) technologies, the SMRT approach has several advantages, including long read length, high speed, PCR-free and the capability of direct detection of epigenetic modifications. However, the disadvantage of its low accuracy, most of which resulted from insertions and deletions, is also notable. So, the raw sequence data need to be corrected before assembly. Up to now, the SMRT is a good fit for applications in the de novo genomic sequencing and the high-quality assemblies of small genomes. In the future, it is expected to play an important role in epigenetics, transcriptomic sequencing, and assemblies of large genomes.

Partially Ionized Plasmas, Including the Third Symposium on Uranium Plasmas

NASA Technical Reports Server (NTRS)

Krishnan, M.

1976-01-01

Fundamentals of both electrically and fission generated plasmas are discussed. Research in gaseous fuel reactors using uranium hexafluoride is described and other partially ionized plasma applications are discussed.

Documents about Measurement Competency Under Acquisition Agreements

EPA Pesticide Factsheets

These document convey EPA policy requiring that organizations generating environmental data under Agency-funded acquisitions submit documentation of their competency, which may include participation in applicable certification and/or accreditation programs

Sample presentation, sources of error and future perspectives on the application of vibrational spectroscopy in the wine industry.

PubMed

Cozzolino, Daniel

2015-03-30

Vibrational spectroscopy encompasses a number of techniques and methods including ultra-violet, visible, Fourier transform infrared or mid infrared, near infrared and Raman spectroscopy. The use and application of spectroscopy generates spectra containing hundreds of variables (absorbances at each wavenumbers or wavelengths), resulting in the production of large data sets representing the chemical and biochemical wine fingerprint. Multivariate data analysis techniques are then required to handle the large amount of data generated in order to interpret the spectra in a meaningful way in order to develop a specific application. This paper focuses on the developments of sample presentation and main sources of error when vibrational spectroscopy methods are applied in wine analysis. Recent and novel applications will be discussed as examples of these developments. © 2014 Society of Chemical Industry.

Applications of biological pores in nanomedicine, sensing, and nanoelectronics

PubMed Central

Majd, Sheereen; Yusko, Erik C; Billeh, Yazan N; Macrae, Michael X; Yang, Jerry; Mayer, Michael

2011-01-01

Biological protein pores and pore-forming peptides can generate a pathway for the flux of ions and other charged or polar molecules across cellular membranes. In nature, these nanopores have diverse and essential functions that range from maintaining cell homeostasis and participating in cell signaling to activating or killing cells. The combination of the nanoscale dimensions and sophisticated – often regulated – functionality of these biological pores make them particularly attractive for the growing field of nanobiotechnology. Applications range from single-molecule sensing to drug delivery and targeted killing of malignant cells. Potential future applications may include the use of nanopores for single strand DNA sequencing and for generating bio-inspired, and possibly, biocompatible visual detection systems and batteries. This article reviews the current state of applications of pore-forming peptides and proteins in nanomedicine, sensing, and nanoelectronics. PMID:20561776

A Review of the CMOS Buried Double Junction (BDJ) Photodetector and its Applications

PubMed Central

Feruglio, Sylvain; Lu, Guo-Neng; Garda, Patrick; Vasilescu, Gabriel

2008-01-01

A CMOS Buried Double Junction PN (BDJ) photodetector consists of two vertically-stacked photodiodes. It can be operated as a photodiode with improved performance and wavelength-sensitive response. This paper presents a review of this device and its applications. The CMOS implementation and operating principle are firstly described. This includes the description of several key aspects directly related to the device performances, such as surface reflection, photon absorption and electron-hole pair generation, photocurrent and dark current generation, etc. SPICE modelling of the detector is then presented. Next, design and process considerations are proposed in order to improve the BDJ performance. Finally, several BDJ-detector-based image sensors provide a survey of their applications. PMID:27873887

Single-photon ultrashort-lived radionuclides: symposium proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paras, P.; Thiessen, J.W.

1985-01-01

The purpose was to define the current role and state-of-the-art regarding the development, clinical applications, and usefulness of generator-produced single-photon ultrashort-lived radionuclides (SPUSLR's) and to predict their future impact on medicine. Special emphasis was placed on the generator production of iridium-191, gold-195, and krypton-81. This report contains expanded summaries of the included papers. (ACR)

Generation and delivery device for ozone gas

NASA Technical Reports Server (NTRS)

Andrews, Craig C. (Inventor); Murphy, Oliver J. (Inventor)

2002-01-01

The present invention provides an ozone generation and delivery system that lends itself to small scale applications and requires very low maintenance. The system preferably includes an anode reservoir and a cathode phase separator each having a hydrophobic membrane to allow phase separation of produced gases from water. The hydrogen gas, ozone gas and water containing ozone may be delivered under pressure.

Generation and Recovery of Solid Wood Waste in the U.S.

Treesearch

Bob Falk; David McKeever

2012-01-01

North America has a vast system of hardwood and softwood forests, and the wood harvested from this resource is widely used in many applications. These include lumber and other building materials, furniture, crating, containers, pallets and other consumer goods. This wide array of wood products generates not only a large amount of industrial wood by-product during the...

Study of transport of laser-driven relativistic electrons in solid materials

NASA Astrophysics Data System (ADS)

Leblanc, Philippe

With the ultra intense lasers available today, it is possible to generate very hot electron beams in solid density materials. These intense laser-matter interactions result in many applications which include the generation of ultrashort secondary sources of particles and radiation such as ions, neutrons, positrons, x-rays, or even laser-driven hadron therapy. For these applications to become reality, a comprehensive understanding of laser-driven energy transport including hot electron generation through the various mechanisms of ionization, and their subsequent transport in solid density media is required. This study will focus on the characterization of electron transport effects in solid density targets using the state-of- the-art particle-in-cell code PICLS. A number of simulation results will be presented on the topics of ionization propagation in insulator glass targets, non-equilibrium ionization modeling featuring electron impact ionization, and electron beam guiding by the self-generated resistive magnetic field. An empirically derived scaling relation for the resistive magnetic in terms of the laser parameters and material properties is presented and used to derive a guiding condition. This condition may prove useful for the design of future laser-matter interaction experiments.

TEM Pump With External Heat Source And Sink

NASA Technical Reports Server (NTRS)

Nesmith, Bill J.

1991-01-01

Proposed thermoelectric/electromagnetic (TEM) pump driven by external source of heat and by two or more heat pipe radiator heat sink(s). Thermoelectrics generate electrical current to circulate liquid metal in secondary loop of two-fluid-loop system. Intended for use with space and terrestrial dual loop liquid metal nuclear reactors. Applications include spacecraft on long missions or terrestrial beacons or scientific instruments having to operate in remote areas for long times. Design modified to include multiple radiators, converters, and ducts, as dictated by particular application.

Investigations and Applications of Field- and Photo-emitted Electron Beams from a Radio Frequency Gun

DOE Office of Scientific and Technical Information (OSTI.GOV)

Panuganti, SriHarsha

Production of quality electron bunches using e cient ways of generation is a crucial aspect of accelerator technology. Radio frequency electron guns are widely used to generate and rapidly accelerate electron beams to relativistic energies. In the current work, we primarily study the charge generation processes of photoemission and eld emission inside an RF gun installed at Fermilab's High Brightness Electron Source Laboratory (HBESL). Speci cally, we study and characterize second-order nonlinear photoemission from a Cesium Telluride (Cs 2Te) semiconductor photocathode, and eld emission from carbon based cathodes including diamond eld emission array (DFEA) and carbon nanotube (CNT) cathodes locatedmore » in the RF gun's cavity. Finally, we discuss the application experiments conducted at the facility to produce soft x-rays via inverse Compton scattering (ICS), and to generate uniformly lled ellipsoidal bunches and temporally shaped electron beams from the Cs 2Te photocathode.« less

75 FR 17404 - Twin Valleys Public Power District; Notice of Preliminary Permit Application Accepted for Filing...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-06

...; (2) a powerhouse containing one Kaplan generating unit having an installed capacity of 800 kilowatts... Commission's website ( http://www.ferc.gov/docs-filing/ferconline.asp ) under the ``eFiling'' link. For a... this project, including a copy of the application, can be viewed or printed on the ``eLibrary'' link of...

SpectralNET – an application for spectral graph analysis and visualization

PubMed Central

Forman, Joshua J; Clemons, Paul A; Schreiber, Stuart L; Haggarty, Stephen J

2005-01-01

Background Graph theory provides a computational framework for modeling a variety of datasets including those emerging from genomics, proteomics, and chemical genetics. Networks of genes, proteins, small molecules, or other objects of study can be represented as graphs of nodes (vertices) and interactions (edges) that can carry different weights. SpectralNET is a flexible application for analyzing and visualizing these biological and chemical networks. Results Available both as a standalone .NET executable and as an ASP.NET web application, SpectralNET was designed specifically with the analysis of graph-theoretic metrics in mind, a computational task not easily accessible using currently available applications. Users can choose either to upload a network for analysis using a variety of input formats, or to have SpectralNET generate an idealized random network for comparison to a real-world dataset. Whichever graph-generation method is used, SpectralNET displays detailed information about each connected component of the graph, including graphs of degree distribution, clustering coefficient by degree, and average distance by degree. In addition, extensive information about the selected vertex is shown, including degree, clustering coefficient, various distance metrics, and the corresponding components of the adjacency, Laplacian, and normalized Laplacian eigenvectors. SpectralNET also displays several graph visualizations, including a linear dimensionality reduction for uploaded datasets (Principal Components Analysis) and a non-linear dimensionality reduction that provides an elegant view of global graph structure (Laplacian eigenvectors). Conclusion SpectralNET provides an easily accessible means of analyzing graph-theoretic metrics for data modeling and dimensionality reduction. SpectralNET is publicly available as both a .NET application and an ASP.NET web application from . Source code is available upon request. PMID:16236170

SpectralNET--an application for spectral graph analysis and visualization.

PubMed

Forman, Joshua J; Clemons, Paul A; Schreiber, Stuart L; Haggarty, Stephen J

2005-10-19

Graph theory provides a computational framework for modeling a variety of datasets including those emerging from genomics, proteomics, and chemical genetics. Networks of genes, proteins, small molecules, or other objects of study can be represented as graphs of nodes (vertices) and interactions (edges) that can carry different weights. SpectralNET is a flexible application for analyzing and visualizing these biological and chemical networks. Available both as a standalone .NET executable and as an ASP.NET web application, SpectralNET was designed specifically with the analysis of graph-theoretic metrics in mind, a computational task not easily accessible using currently available applications. Users can choose either to upload a network for analysis using a variety of input formats, or to have SpectralNET generate an idealized random network for comparison to a real-world dataset. Whichever graph-generation method is used, SpectralNET displays detailed information about each connected component of the graph, including graphs of degree distribution, clustering coefficient by degree, and average distance by degree. In addition, extensive information about the selected vertex is shown, including degree, clustering coefficient, various distance metrics, and the corresponding components of the adjacency, Laplacian, and normalized Laplacian eigenvectors. SpectralNET also displays several graph visualizations, including a linear dimensionality reduction for uploaded datasets (Principal Components Analysis) and a non-linear dimensionality reduction that provides an elegant view of global graph structure (Laplacian eigenvectors). SpectralNET provides an easily accessible means of analyzing graph-theoretic metrics for data modeling and dimensionality reduction. SpectralNET is publicly available as both a .NET application and an ASP.NET web application from http://chembank.broad.harvard.edu/resources/. Source code is available upon request.

Incorporating Manual and Autonomous Code Generation

NASA Technical Reports Server (NTRS)

McComas, David

1998-01-01

Code can be generated manually or using code-generated software tools, but how do you interpret the two? This article looks at a design methodology that combines object-oriented design with autonomic code generation for attitude control flight software. Recent improvements in space flight computers are allowing software engineers to spend more time engineering the applications software. The application developed was the attitude control flight software for an astronomical satellite called the Microwave Anisotropy Probe (MAP). The MAP flight system is being designed, developed, and integrated at NASA's Goddard Space Flight Center. The MAP controls engineers are using Integrated Systems Inc.'s MATRIXx for their controls analysis. In addition to providing a graphical analysis for an environment, MATRIXx includes an autonomic code generation facility called AutoCode. This article examines the forces that shaped the final design and describes three highlights of the design process: (1) Defining the manual to autonomic code interface; (2) Applying object-oriented design to the manual flight code; (3) Implementing the object-oriented design in C.

Automated Translation of Safety Critical Application Software Specifications into PLC Ladder Logic

NASA Technical Reports Server (NTRS)

Leucht, Kurt W.; Semmel, Glenn S.

2008-01-01

The numerous benefits of automatic application code generation are widely accepted within the software engineering community. A few of these benefits include raising the abstraction level of application programming, shorter product development time, lower maintenance costs, and increased code quality and consistency. Surprisingly, code generation concepts have not yet found wide acceptance and use in the field of programmable logic controller (PLC) software development. Software engineers at the NASA Kennedy Space Center (KSC) recognized the need for PLC code generation while developing their new ground checkout and launch processing system. They developed a process and a prototype software tool that automatically translates a high-level representation or specification of safety critical application software into ladder logic that executes on a PLC. This process and tool are expected to increase the reliability of the PLC code over that which is written manually, and may even lower life-cycle costs and shorten the development schedule of the new control system at KSC. This paper examines the problem domain and discusses the process and software tool that were prototyped by the KSC software engineers.

NiftyNet: a deep-learning platform for medical imaging.

PubMed

Gibson, Eli; Li, Wenqi; Sudre, Carole; Fidon, Lucas; Shakir, Dzhoshkun I; Wang, Guotai; Eaton-Rosen, Zach; Gray, Robert; Doel, Tom; Hu, Yipeng; Whyntie, Tom; Nachev, Parashkev; Modat, Marc; Barratt, Dean C; Ourselin, Sébastien; Cardoso, M Jorge; Vercauteren, Tom

2018-05-01

Medical image analysis and computer-assisted intervention problems are increasingly being addressed with deep-learning-based solutions. Established deep-learning platforms are flexible but do not provide specific functionality for medical image analysis and adapting them for this domain of application requires substantial implementation effort. Consequently, there has been substantial duplication of effort and incompatible infrastructure developed across many research groups. This work presents the open-source NiftyNet platform for deep learning in medical imaging. The ambition of NiftyNet is to accelerate and simplify the development of these solutions, and to provide a common mechanism for disseminating research outputs for the community to use, adapt and build upon. The NiftyNet infrastructure provides a modular deep-learning pipeline for a range of medical imaging applications including segmentation, regression, image generation and representation learning applications. Components of the NiftyNet pipeline including data loading, data augmentation, network architectures, loss functions and evaluation metrics are tailored to, and take advantage of, the idiosyncracies of medical image analysis and computer-assisted intervention. NiftyNet is built on the TensorFlow framework and supports features such as TensorBoard visualization of 2D and 3D images and computational graphs by default. We present three illustrative medical image analysis applications built using NiftyNet infrastructure: (1) segmentation of multiple abdominal organs from computed tomography; (2) image regression to predict computed tomography attenuation maps from brain magnetic resonance images; and (3) generation of simulated ultrasound images for specified anatomical poses. The NiftyNet infrastructure enables researchers to rapidly develop and distribute deep learning solutions for segmentation, regression, image generation and representation learning applications, or extend the platform to new applications. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

Next-Generation Technologies for Multiomics Approaches Including Interactome Sequencing

PubMed Central

Ohashi, Hiroyuki; Miyamoto-Sato, Etsuko

2015-01-01

The development of high-speed analytical techniques such as next-generation sequencing and microarrays allows high-throughput analysis of biological information at a low cost. These techniques contribute to medical and bioscience advancements and provide new avenues for scientific research. Here, we outline a variety of new innovative techniques and discuss their use in omics research (e.g., genomics, transcriptomics, metabolomics, proteomics, and interactomics). We also discuss the possible applications of these methods, including an interactome sequencing technology that we developed, in future medical and life science research. PMID:25649523

Integrated optical phased arrays for quasi-Bessel-beam generation.

PubMed

Notaros, Jelena; Poulton, Christopher V; Byrd, Matthew J; Raval, Manan; Watts, Michael R

2017-09-01

Integrated optical phased arrays for generating quasi-Bessel beams are proposed and experimentally demonstrated in a CMOS-compatible platform. Owing to their elongated central beams, Bessel beams have applications in a range of fields, including multiparticle trapping and laser lithography. In this Letter, continuous Bessel theory is manipulated to formulate the phase and amplitude conditions necessary for generating free-space-propagating Bessel-Gauss beams using on-chip optical phased arrays. Discussion of the effects of select phased array parameters on the generated beam's figures of merit is included. A one-dimensional splitter-tree-based phased array architecture is modified to enable arbitrary passive control of the array's element phase and amplitude distributions. This architecture is used to experimentally demonstrate on-chip quasi-Bessel-beam generation with a ∼14  mm Bessel length and ∼30  μm power full width at half maximum.

Photocatalytic Hybrid Semiconductor-Metal Nanoparticles; from Synergistic Properties to Emerging Applications.

PubMed

Waiskopf, Nir; Ben-Shahar, Yuval; Banin, Uri

2018-04-14

Hybrid semiconductor-metal nanoparticles (HNPs) manifest unique combined and often synergetic properties stemming from the materials combination. These structures exhibit spatial charge separation across the semiconductor-metal junction upon light absorption, enabling their use as photocatalysts. So far, the main impetus of photocatalysis research in HNPs addresses their functionality in solar fuel generation. Recently, it was discovered that HNPs are functional in efficient photocatalytic generation of reactive oxygen species (ROS). This has opened the path for their implementation in diverse biomedical and industrial applications where high spatially temporally resolved ROS formation is essential. Here, the latest studies on the synergistic characteristics of HNPs are summarized, including their optical, electrical, and chemical properties and their photocatalytic function in the field of solar fuel generation is briefly discussed. Recent studies are then focused concerning photocatalytic ROS formation with HNPs under aerobic conditions. The emergent applications of this capacity are then highlighted, including light-induced modulation of enzymatic activity, photodynamic therapy, antifouling, wound healing, and as novel photoinitiators for 3D-printing. The superb photophysical and photocatalytic properties of HNPs offer already clear advantages for their utility in scenarios requiring on-demand light-induced radical formation and the full potential of HNPs in this context is yet to be revealed. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Benefit-cost methodology study with example application of the use of wind generators

NASA Technical Reports Server (NTRS)

Zimmer, R. P.; Justus, C. G.; Mason, R. M.; Robinette, S. L.; Sassone, P. G.; Schaffer, W. A.

1975-01-01

An example application for cost-benefit methodology is presented for the use of wind generators. The approach adopted for the example application consisted of the following activities: (1) surveying of the available wind data and wind power system information, (2) developing models which quantitatively described wind distributions, wind power systems, and cost-benefit differences between conventional systems and wind power systems, and (3) applying the cost-benefit methodology to compare a conventional electrical energy generation system with systems which included wind power generators. Wind speed distribution data were obtained from sites throughout the contiguous United States and were used to compute plant factor contours shown on an annual and seasonal basis. Plant factor values (ratio of average output power to rated power) are found to be as high as 0.6 (on an annual average basis) in portions of the central U. S. and in sections of the New England coastal area. Two types of wind power systems were selected for the application of the cost-benefit methodology. A cost-benefit model was designed and implemented on a computer to establish a practical tool for studying the relative costs and benefits of wind power systems under a variety of conditions and to efficiently and effectively perform associated sensitivity analyses.

Economic viability of photovoltaic power for development assistance applications

NASA Technical Reports Server (NTRS)

Bifano, W. J.

1982-01-01

This paper briefly discusses the development assistance market and examines a number of specific photovoltaic (PV) development assistance field tests, including water pumping/grain grinding (Tangaye, Upper Volta), vaccine refrigerators slated for deployment in 24 countries, rural medical centers to be installed in Ecuador, Guyana, Kenya and Zimbabwe, and remote earth stations to be deployed in the near future. A comparison of levelized energy cost for diesel generators and PV systems covering a range of annual energy consumptions is also included. The analysis does not consider potential societal, environmental or political benefits associated with PV power. PV systems are shown to be competitive with diesel generators, based on life cycle cost considerations, assuming a system price of $20/W(peak), for applications having an annual energy demand of up to 6000 kilowatt-hours per year.

Performance Evaluation of an Intel Haswell- and Ivy Bridge-Based Supercomputer Using Scientific and Engineering Applications

NASA Technical Reports Server (NTRS)

Saini, Subhash; Hood, Robert T.; Chang, Johnny; Baron, John

2016-01-01

We present a performance evaluation conducted on a production supercomputer of the Intel Xeon Processor E5- 2680v3, a twelve-core implementation of the fourth-generation Haswell architecture, and compare it with Intel Xeon Processor E5-2680v2, an Ivy Bridge implementation of the third-generation Sandy Bridge architecture. Several new architectural features have been incorporated in Haswell including improvements in all levels of the memory hierarchy as well as improvements to vector instructions and power management. We critically evaluate these new features of Haswell and compare with Ivy Bridge using several low-level benchmarks including subset of HPCC, HPCG and four full-scale scientific and engineering applications. We also present a model to predict the performance of HPCG and Cart3D within 5%, and Overflow within 10% accuracy.

Nanotechnologies for efficient solar and wind energy harvesting and storage

NASA Astrophysics Data System (ADS)

Eldada, Louay A.

2010-08-01

We describe nanotechnologies used to improve the efficient harvest of energy from the Sun and the wind, and the efficient storage of energy in secondary batteries and ultracapacitors, for use in a variety of applications including smart grids, electric vehicles, and portable electronics. We demonstrate high-quality nanostructured copper indium gallium selenide (CIGS) thin films for photovoltaic (PV) applications. The self-assembly of nanoscale p-n junction networks creates n-type networks that act as preferential electron pathways, and p-type networks that act as preferential hole pathways, allowing positive and negative charges to travel to the contacts in physically separated paths, reducing charge recombination. We also describe PV nanotechnologies used to enhance light trapping, photon absorption, charge generation, charge transport, and current collection. Furthermore, we describe nanotechnologies used to improve the efficiency of power-generating wind turbines. These technologies include nanoparticle-containing lubricants that reduce the friction generated from the rotation of the turbines, nanocoatings for de-icing and self-cleaning technologies, and advanced nanocomposites that provide lighter and stronger wind blades. Finally, we describe nanotechnologies used in advanced secondary batteries and ultracapacitors. Nanostructured powder-based and carbon-nanotube-based cathodes and anodes with ultra-high surface areas boost the energy and power densities in secondary batteries, including lithium-ion and sodium-sulfur batteries. Nanostructured carbon materials are also controlled on a molecular level to offer large surface areas for the electrodes of ultracapacitors, allowing to store and supply large bursts of energy needed in some applications.

Automatic code generation in SPARK: Applications of computer algebra and compiler-compilers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nataf, J.M.; Winkelmann, F.

We show how computer algebra and compiler-compilers are used for automatic code generation in the Simulation Problem Analysis and Research Kernel (SPARK), an object oriented environment for modeling complex physical systems that can be described by differential-algebraic equations. After a brief overview of SPARK, we describe the use of computer algebra in SPARK's symbolic interface, which generates solution code for equations that are entered in symbolic form. We also describe how the Lex/Yacc compiler-compiler is used to achieve important extensions to the SPARK simulation language, including parametrized macro objects and steady-state resetting of a dynamic simulation. The application of thesemore » methods to solving the partial differential equations for two-dimensional heat flow is illustrated.« less

Automatic code generation in SPARK: Applications of computer algebra and compiler-compilers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nataf, J.M.; Winkelmann, F.

We show how computer algebra and compiler-compilers are used for automatic code generation in the Simulation Problem Analysis and Research Kernel (SPARK), an object oriented environment for modeling complex physical systems that can be described by differential-algebraic equations. After a brief overview of SPARK, we describe the use of computer algebra in SPARK`s symbolic interface, which generates solution code for equations that are entered in symbolic form. We also describe how the Lex/Yacc compiler-compiler is used to achieve important extensions to the SPARK simulation language, including parametrized macro objects and steady-state resetting of a dynamic simulation. The application of thesemore » methods to solving the partial differential equations for two-dimensional heat flow is illustrated.« less

Generation of transgene-free induced pluripotent stem cells with non-viral methods.

PubMed

Wang, Tao; Zhao, Hua-shan; Zhang, Qiu-ling; Xu, Chang-lin; Liu, Chang-bai

2013-03-01

Induced pluripotent stem (iPS) cells were originally generated from mouse fibroblasts by enforced expression of Yamanaka factors (Oct3/4, Sox2, Klf4, and c-Myc). The technique was quickly reproduced with human fibroblasts or mesenchymal stem cells. Although having been showed therapeutic potential in animal models of sickle cell anemia and Parkinson's disease, iPS cells generated by viral methods do not suit all the clinical applications. Various non-viral methods have appeared in recent years for application of iPS cells in cell transplantation therapy. These methods mainly include DNA vector-based approaches, transfection of mRNA, and transduction of reprogramming proteins. This review summarized these non-viral methods and compare the advantages, disadvantages, efficiency, and safety of these methods.

Development and Applications of the GOES Sounder Products

NASA Astrophysics Data System (ADS)

Li, Jun; Menzel, W. P.; Li, Z.; Wade, G.; Schmit, T. J.; Li, J. L.; Aune, R.; Schreiner, A. J.; Schmidt, C. C.; Genkova, I.

Since 1994 a new generation of Geostationary Operational Environmental Satellite GOES Sounders GOES-8 9 10 11 12 has been measuring radiances in 18 infrared spectral bands ranging from approximately 3 7um - 14 7 um This data has been used to provide atmospheric sounding and cloud products for meteorological applications on an hourly basis over North America and adjacent oceanic regions The products include atmospheric temperature and moisture profiles total precipitable water cloud-top pressure water-vapor tracked winds etc Products are generated operationally by NOAA NESDIS in Washington D C Some Sounder products including total column ozone are also produced at the Cooperative Institute for Meteorological Satellite Studies at the University of Wisconsin-Madison Applications of those products include nowcasting and forecasting of weather events assimilation of cloud products into regional numerical forecast models and monitoring of temperature and moisture changes during active convective periods The impact of GOES Sounder products on numerical model forecasts will be demonstrated Furthermore recent improvements to several of the products have been made by taking into account the GOES Sounder temporal and spatial information within the processing algorithms These improvements and implications thereof will be presented and discussed

Modelface: an Application Programming Interface (API) for Homology Modeling Studies Using Modeller Software

PubMed Central

Sakhteman, Amirhossein; Zare, Bijan

2016-01-01

An interactive application, Modelface, was presented for Modeller software based on windows platform. The application is able to run all steps of homology modeling including pdb to fasta generation, running clustal, model building and loop refinement. Other modules of modeler including energy calculation, energy minimization and the ability to make single point mutations in the PDB structures are also implemented inside Modelface. The API is a simple batch based application with no memory occupation and is free of charge for academic use. The application is also able to repair missing atom types in the PDB structures making it suitable for many molecular modeling studies such as docking and molecular dynamic simulation. Some successful instances of modeling studies using Modelface are also reported. PMID:28243276

The Generation of Near-Real Time Data Products for MODIS

NASA Astrophysics Data System (ADS)

Teague, M.; Schmaltz, J. E.; Ilavajhala, S.; Ye, G.; Masuoka, E.; Murphy, K. J.; Michael, K.

2010-12-01

The GSFC Terrestrial Information Systems Branch (614.5) operate the Land and Atmospheres Near-real-time Capability for EOS (LANCE-MODIS) system. Other LANCE elements include -AIRS, -MLS, -OMI, and -AMSR-E. LANCE-MODIS incorporates the former Rapid Response system and will, in early 2011, include the Fire Information for Resource Management System (FIRMS). The purpose of LANCE is to provide applications users with a variety of products on a near-real time basis. The LANCE-MODIS data products include Level 1 (L1), L2 fire, snow, sea ice, cloud mask/profiles, aerosols, clouds, land surface reflectance, land surface temperature, and L2G and L3 gridded, daily, land surface reflectance products. Data are available either by ftp access (pull) or by subscription (push) and the L1 and L2 data products are available within an average of 2.5 hours of the observation time. The use of ancillary data products input to the standard science algorithms has been modified in order to obtain these latencies. The resulting products have been approved for applications use by the MODIS Science Team. The http://lance.nasa.gov site provides registration information and extensive information concerning the MODIS data products and imagery including a comparison between the LANCE-MODIS and the standard science-quality products generated by the MODAPS system. The LANCE-MODIS system includes a variety of tools that enable users to manipulate the data products including: parameter, band, and geographic subsetting, re-projection, mosaicing, and generation of data in the GeoTIFF format. In most instances the data resulting from use of these tools has a latency of less than 3 hours. Access to these tools is available through a Web Coverage Service. A Google Earth/Web Mapping Service is available to access image products. LANCE-MODIS supports a wide variety of applications users in civilian, military, and foreign agencies as well as universities and the private sector. Examples of applications are: Flood Mapping, Famine relief, Food and Agriculture, Hazards and Disasters, and Weather.

Quantifying the Opportunity Space for Future Electricity Generation: An Application to Offshore Wind Energy in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marcy, Cara; Beiter, Philipp

2016-09-01

This report provides a high-level indicator of the future electricity demand for additional electric power generation that is not met by existing generation sources between 2015 and 2050. The indicator is applied to coastal regions, including the Great Lakes, to assess the regional opportunity space for offshore wind. An assessment of opportunity space can be a first step in determining the prospects and the system value of a technology. The metric provides the maximal amount of additional generation that is likely required to satisfy load in future years.

Description of a computer program and numerical techniques for developing linear perturbation models from nonlinear systems simulations

NASA Technical Reports Server (NTRS)

Dieudonne, J. E.

1978-01-01

A numerical technique was developed which generates linear perturbation models from nonlinear aircraft vehicle simulations. The technique is very general and can be applied to simulations of any system that is described by nonlinear differential equations. The computer program used to generate these models is discussed, with emphasis placed on generation of the Jacobian matrices, calculation of the coefficients needed for solving the perturbation model, and generation of the solution of the linear differential equations. An example application of the technique to a nonlinear model of the NASA terminal configured vehicle is included.

Electric Potential and Electric Field Imaging with Applications

NASA Technical Reports Server (NTRS)

Generazio, Ed

2016-01-01

The technology and techniques for remote quantitative imaging of electrostatic potentials and electrostatic fields in and around objects and in free space is presented. Electric field imaging (EFI) technology may be applied to characterize intrinsic or existing electric potentials and electric fields, or an externally generated electrostatic field may be used for (illuminating) volumes to be inspected with EFI. The baseline sensor technology, electric field sensor (e-sensor), and its construction, optional electric field generation (quasistatic generator), and current e-sensor enhancements (ephemeral e-sensor) are discussed. Demonstrations for structural, electronic, human, and memory applications are shown. This new EFI capability is demonstrated to reveal characterization of electric charge distribution, creating a new field of study that embraces areas of interest including electrostatic discharge mitigation, crime scene forensics, design and materials selection for advanced sensors, dielectric morphology of structures, inspection of containers, inspection for hidden objects, tether integrity, organic molecular memory, and medical diagnostic and treatment efficacy applications such as cardiac polarization wave propagation and electromyography imaging.

Generation of Quality Pulses for Control of Qubit/Quantum Memory Spin States: Experimental and Simulation

DTIC Science & Technology

2016-09-01

TECHNICAL REPORT 3046 September 2016 GENERATION OF QUALITY PULSES FOR CONTROL OF QUBIT/QUANTUM MEMORY SPIN STATES: EXPERIMENTAL AND SIMULATION...control circuitry for control of electron/ nuclear spin states of qubits/quantum memory applicable to semiconductor, superconductor, ionic, and...coherence time of the qubit/ memory , we present as an example the integration of cryogenic superconductor components, including filters and

Dynamic Test Generation for Large Binary Programs

DTIC Science & Technology

2009-11-12

the fuzzing@whitestar.linuxbox.orgmailing list, including Jared DeMott, Disco Jonny, and Ari Takanen, for discussions on fuzzing tradeoffs. Martin...as is the case for large applications where exercising all execution paths is virtually hopeless anyway. This point will be further discussed in...consumes trace files generated by iDNA and virtually re-executes the recorded runs. TruScan offers several features that substantially simplify symbolic

Generation and delivery device for ozone gas and ozone dissolved in water

NASA Technical Reports Server (NTRS)

Andrews, Craig C. (Inventor); Murphy, Oliver J. (Inventor)

2004-01-01

The present invention provides an ozone generation and delivery system that lends itself to small scale applications and requires very low maintenance. The system preferably includes an anode reservoir and a cathode phase separator each having a hydrophobic membrane to allow phase separation of produced gases from water. The hydrogen gas, ozone gas and water containing ozone may be delivered under pressure.

Automated Weight-Window Generation for Threat Detection Applications Using ADVANTG

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mosher, Scott W; Miller, Thomas Martin; Evans, Thomas M

2009-01-01

Deterministic transport codes have been used for some time to generate weight-window parameters that can improve the efficiency of Monte Carlo simulations. As the use of this hybrid computational technique is becoming more widespread, the scope of applications in which it is being applied is expanding. An active source of new applications is the field of homeland security--particularly the detection of nuclear material threats. For these problems, automated hybrid methods offer an efficient alternative to trial-and-error variance reduction techniques (e.g., geometry splitting or the stochastic weight window generator). The ADVANTG code has been developed to automate the generation of weight-windowmore » parameters for MCNP using the Consistent Adjoint Driven Importance Sampling method and employs the TORT or Denovo 3-D discrete ordinates codes to generate importance maps. In this paper, we describe the application of ADVANTG to a set of threat-detection simulations. We present numerical results for an 'active-interrogation' problem in which a standard cargo container is irradiated by a deuterium-tritium fusion neutron generator. We also present results for two passive detection problems in which a cargo container holding a shielded neutron or gamma source is placed near a portal monitor. For the passive detection problems, ADVANTG obtains an O(10{sup 4}) speedup and, for a detailed gamma spectrum tally, an average O(10{sup 2}) speedup relative to implicit-capture-only simulations, including the deterministic calculation time. For the active-interrogation problem, an O(10{sup 4}) speedup is obtained when compared to a simulation with angular source biasing and crude geometry splitting.« less

Applications of biological pores in nanomedicine, sensing, and nanoelectronics.

PubMed

Majd, Sheereen; Yusko, Erik C; Billeh, Yazan N; Macrae, Michael X; Yang, Jerry; Mayer, Michael

2010-08-01

Biological protein pores and pore-forming peptides can generate a pathway for the flux of ions and other charged or polar molecules across cellular membranes. In nature, these nanopores have diverse and essential functions that range from maintaining cell homeostasis and participating in cell signaling to activating or killing cells. The combination of the nanoscale dimensions and sophisticated - often regulated - functionality of these biological pores make them particularly attractive for the growing field of nanobiotechnology. Applications range from single-molecule sensing to drug delivery and targeted killing of malignant cells. Potential future applications may include the use of nanopores for single strand DNA sequencing and for generating bio-inspired, and possibly, biocompatible visual detection systems and batteries. This article reviews the current state of applications of pore-forming peptides and proteins in nanomedicine, sensing, and nanoelectronics. Copyright © 2010 Elsevier Ltd. All rights reserved.

Experience with 3-D composite grids

NASA Technical Reports Server (NTRS)

Benek, J. A.; Donegan, T. L.; Suhs, N. E.

1987-01-01

Experience with the three-dimensional (3-D), chimera grid embedding scheme is described. Applications of the inviscid version to a multiple-body configuration, a wind/body/tail configuration, and an estimate of wind tunnel wall interference are described. Applications to viscous flows include a 3-D cavity and another multi-body configuration. A variety of grid generators is used, and several embedding strategies are described.

Technology and Curriculum Standards: How Well Do Internet-Based Learning Games Support Common Core Standards for Mathematics?

ERIC Educational Resources Information Center

Bingham, Teri; Ray, Jan

2013-01-01

In an effort to keep up with the new generation of digital learners, educators are integrating multiple forms of technology into their teaching, including online learning game applications. The purpose of this study was to determine the degree to which internet-based learning game applications selected by preservice teachers were aligned with the…

75 FR 69425 - Qualified Hydro 30, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

... vertical Kaplan turbine-generator units with a combined capacity of 2.5 megawatts; (5) a new 3-MVA.../ferconline.asp ) under the ``eFiling'' link. For a simpler method of submitting text only comments, click on... this project, including a copy of the application can be viewed or printed on the ``eLibrary'' link of...

76 FR 11240 - Qualified Hydro 34, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-01

... and would consist of the following: (1) One vertical Kaplan turbine and generator unit rated at 25... characters, without prior registration, using the eComment system at http://www.ferc.gov/docs-filing/ecomment... information about this project, including a copy of the application, can be viewed or printed on the ``e...

75 FR 70224 - Qualified Hydro 29, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-17

...-foot diameter penstock; (4) two vertical Kaplan turbine-generator units with a combined capacity of 7.0... ) under the ``eFiling'' link. For a simpler method of submitting text only comments, click on ``Quick... project, including a copy of the application can be viewed or printed on the ``eLibrary'' link of...

75 FR 69426 - Qualified Hydro 31, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

... penstock; (4) two vertical Kaplan turbine- generator units with a combined capacity of 3.5 megawatts; (5) a.../ferconline.asp ) under the ``eFiling'' link. For a simpler method of submitting text only comments, click on... this project, including a copy of the application can be viewed or printed on the ``eLibrary'' link of...

The pumping lid: investigating multi-material 3D printing for equipment-free, programmable generation of positive and negative pressures for microfluidic applications.

PubMed

Begolo, Stefano; Zhukov, Dmitriy V; Selck, David A; Li, Liang; Ismagilov, Rustem F

2014-12-21

Equipment-free pumping is a challenging problem and an active area of research in microfluidics, with applications for both laboratory and limited-resource settings. This paper describes the pumping lid method, a strategy to achieve equipment-free pumping by controlled generation of pressure. Pressure was generated using portable, lightweight, and disposable parts that can be integrated with existing microfluidic devices to simplify workflow and eliminate the need for pumping equipment. The development of this method was enabled by multi-material 3D printing, which allows fast prototyping, including composite parts that combine materials with different mechanical properties (e.g. both rigid and elastic materials in the same part). The first type of pumping lid we describe was used to produce predictable positive or negative pressures via controlled compression or expansion of gases. A model was developed to describe the pressures and flow rates generated with this approach and it was validated experimentally. Pressures were pre-programmed by the geometry of the parts and could be tuned further even while the experiment was in progress. Using multiple lids or a composite lid with different inlets enabled several solutions to be pumped independently in a single device. The second type of pumping lid, which relied on vapor-liquid equilibrium to generate pressure, was designed, modeled, and experimentally characterized. The pumping lid method was validated by controlling flow in different types of microfluidic applications, including the production of droplets, control of laminar flow profiles, and loading of SlipChip devices. We believe that applying the pumping lid methodology to existing microfluidic devices will enhance their use as portable diagnostic tools in limited resource settings as well as accelerate adoption of microfluidics in laboratories.

Photovoltaic tests and applications project

NASA Technical Reports Server (NTRS)

1978-01-01

The activities and accomplishments of the Photovoltaic Tests and Applications Project during the period April 1976 through June 1977 are summarized. Results of efforts to identify potential near-term photovoltaic applications and users are discussed, including the outcome of an extensive survey of Federal government agencies. The status of application experiments is presented. Various general engineering efforts are reported, including the design and construction of a photovoltaic Systems Test Facility. Efforts to develop a high efficiency 10 kVA self-commutated inverter and controller specifically designed for photovoltaic systems are also discussed. The results of a wide variety of activities in the area of photovoltaic measurements and standards are related. Documents generated by the Project during the reporting period are listed in an Appendix.

All about Eve: Secret Sharing using Quantum Effects

NASA Technical Reports Server (NTRS)

Jackson, Deborah J.

2005-01-01

This document discusses the nature of light (including classical light and photons), encryption, quantum key distribution (QKD), light polarization and beamsplitters and their application to information communication. A quantum of light represents the smallest possible subdivision of radiant energy (light) and is called a photon. The QKD key generation sequence is outlined including the receiver broadcasting the initial signal indicating reception availability, timing pulses from the sender to provide reference for gated detection of photons, the sender generating photons through random polarization while the receiver detects photons with random polarization and communicating via data link to mutually establish random keys. The QKD network vision includes inter-SATCOM, point-to-point Gnd Fiber and SATCOM-fiber nodes. QKD offers an unconditionally secure method of exchanging encryption keys. Ongoing research will focus on how to increase the key generation rate.

Machine learning for quantum dynamics: deep learning of excitation energy transfer properties

DOE PAGES

Häse, Florian; Kreisbeck, Christoph; Aspuru-Guzik, Alán

2017-01-01

Understanding the relationship between the structure of light-harvesting systems and their excitation energy transfer properties is of fundamental importance in many applications including the development of next generation photovoltaics.

Proceedings of the ASPE/MSFC Symposium on Engineering and Productivity Gains from Space Technology

NASA Technical Reports Server (NTRS)

1977-01-01

Aerospace technology findings were examined in regard to nonaerospace applications. Studies of energy generation, materials and processes, earth observation as well as advances and benefits of electronics are included.

Infinitely many symmetries and conservation laws for quad-graph equations via the Gardner method

NASA Astrophysics Data System (ADS)

Rasin, Alexander G.

2010-06-01

The application of the Gardner method for the generation of conservation laws to all the ABS equations is considered. It is shown that all the necessary information for the application of the Gardner method, namely Bäcklund transformations and initial conservation laws, follows from the multidimensional consistency of ABS equations. We also apply the Gardner method to an asymmetric equation which is not included in the ABS classification. An analog of the Gardner method for the generation of symmetries is developed and applied to the discrete Korteweg-de Vries equation. It can also be applied to all the other ABS equations.

Generative Adversarial Networks: An Overview

NASA Astrophysics Data System (ADS)

Creswell, Antonia; White, Tom; Dumoulin, Vincent; Arulkumaran, Kai; Sengupta, Biswa; Bharath, Anil A.

2018-01-01

Generative adversarial networks (GANs) provide a way to learn deep representations without extensively annotated training data. They achieve this through deriving backpropagation signals through a competitive process involving a pair of networks. The representations that can be learned by GANs may be used in a variety of applications, including image synthesis, semantic image editing, style transfer, image super-resolution and classification. The aim of this review paper is to provide an overview of GANs for the signal processing community, drawing on familiar analogies and concepts where possible. In addition to identifying different methods for training and constructing GANs, we also point to remaining challenges in their theory and application.

Multi-wavelength and multiband RE-doped optical fiber source array for WDM-GPON applications

NASA Astrophysics Data System (ADS)

Perez-Sanchez, G. G.; Bertoldi-Martins, I.; Gallion, P.; Gosset, C.; Álvarez-Chávez, J. A.

2013-12-01

In this paper, a multiband, multi-wavelength, all-fibre source array consisting of an 810nm pump laser diode, thretwo fiber splitters and three segments of Er-, Tm- and Nd-doped fiber is proposed for PON applications. In the set-up, cascaded pairs of standard fiber gratings are used for extracting the required multiple wavelengths within their corresponding bands. A thorough design parameter description, optical array details and full simulation results, such as: full multi-wavelength spectrum, peak and average powers for each generated wavelength, linewidth at FWHM for each generated signal, and individual and overall conversion efficiency, will be included in the manuscript.

A web based tool for storing and visualising data generated within a smart home.

PubMed

McDonald, H A; Nugent, C D; Moore, G; Finlay, D D; Hallberg, J

2011-01-01

There is a growing need to re-assess the current approaches available to researchers for storing and managing heterogeneous data generated within a smart home environment. In our current work we have developed the homeML Application; a web based tool to support researchers engaged in the area of smart home research as they perform experiments. Within this paper the homeML Application is presented which includes the fundamental components of the homeML Repository and the homeML Toolkit. Results from a usability study conducted by 10 computer science researchers are presented; the initial results of which have been positive.

Application of NASA ERTS-1 satellite imagery in coastal studies

NASA Technical Reports Server (NTRS)

Magoon, O. T.; Berg, D. W. (Principal Investigator); Hallermeier, R. J.

1973-01-01

There are no author-identified significant results in this report. Review of ERTS-1 imagery indicates that it contains information of great value in coastal engineering studies. A brief introduction is given to the methods by which imagery is generated, and examples of its application to coastal engineering. Specific applications discussed include study of the movement of coastal and nearshore sediment-laden water masses and information for planning and construction in remote areas of the world.

JIGSAW-GEO (1.0): Locally Orthogonal Staggered Unstructured Grid Generation for General Circulation Modelling on the Sphere

NASA Technical Reports Server (NTRS)

Engwirda, Darren

2017-01-01

An algorithm for the generation of non-uniform, locally orthogonal staggered unstructured spheroidal grids is described. This technique is designed to generate very high-quality staggered VoronoiDelaunay meshes appropriate for general circulation modelling on the sphere, including applications to atmospheric simulation, ocean-modelling and numerical weather prediction. Using a recently developed Frontal-Delaunay refinement technique, a method for the construction of high-quality unstructured spheroidal Delaunay triangulations is introduced. A locally orthogonal polygonal grid, derived from the associated Voronoi diagram, is computed as the staggered dual. It is shown that use of the Frontal-Delaunay refinement technique allows for the generation of very high-quality unstructured triangulations, satisfying a priori bounds on element size and shape. Grid quality is further improved through the application of hill-climbing-type optimisation techniques. Overall, the algorithm is shown to produce grids with very high element quality and smooth grading characteristics, while imposing relatively low computational expense. A selection of uniform and non-uniform spheroidal grids appropriate for high-resolution, multi-scale general circulation modelling are presented. These grids are shown to satisfy the geometric constraints associated with contemporary unstructured C-grid-type finite-volume models, including the Model for Prediction Across Scales (MPAS-O). The use of user-defined mesh-spacing functions to generate smoothly graded, non-uniform grids for multi-resolution-type studies is discussed in detail.

JIGSAW-GEO (1.0): locally orthogonal staggered unstructured grid generation for general circulation modelling on the sphere

NASA Astrophysics Data System (ADS)

Engwirda, Darren

2017-06-01

An algorithm for the generation of non-uniform, locally orthogonal staggered unstructured spheroidal grids is described. This technique is designed to generate very high-quality staggered Voronoi-Delaunay meshes appropriate for general circulation modelling on the sphere, including applications to atmospheric simulation, ocean-modelling and numerical weather prediction. Using a recently developed Frontal-Delaunay refinement technique, a method for the construction of high-quality unstructured spheroidal Delaunay triangulations is introduced. A locally orthogonal polygonal grid, derived from the associated Voronoi diagram, is computed as the staggered dual. It is shown that use of the Frontal-Delaunay refinement technique allows for the generation of very high-quality unstructured triangulations, satisfying a priori bounds on element size and shape. Grid quality is further improved through the application of hill-climbing-type optimisation techniques. Overall, the algorithm is shown to produce grids with very high element quality and smooth grading characteristics, while imposing relatively low computational expense. A selection of uniform and non-uniform spheroidal grids appropriate for high-resolution, multi-scale general circulation modelling are presented. These grids are shown to satisfy the geometric constraints associated with contemporary unstructured C-grid-type finite-volume models, including the Model for Prediction Across Scales (MPAS-O). The use of user-defined mesh-spacing functions to generate smoothly graded, non-uniform grids for multi-resolution-type studies is discussed in detail.

Plasma driven neutron/gamma generator

DOEpatents

Leung, Ka-Ngo; Antolak, Arlyn

2015-03-03

An apparatus for the generation of neutron/gamma rays is described including a chamber which defines an ion source, said apparatus including an RF antenna positioned outside of or within the chamber. Positioned within the chamber is a target material. One or more sets of confining magnets are also provided to create a cross B magnetic field directly above the target. To generate neutrons/gamma rays, the appropriate source gas is first introduced into the chamber, the RF antenna energized and a plasma formed. A series of high voltage pulses are then applied to the target. A plasma sheath, which serves as an accelerating gap, is formed upon application of the high voltage pulse to the target. Depending upon the selected combination of source gas and target material, either neutrons or gamma rays are generated, which may be used for cargo inspection, and the like.

Detection of Natural Hazards Generated TEC Perturbations and Related New Applications

NASA Astrophysics Data System (ADS)

Komjathy, A.; Yang, Y.; Langley, R. B.

2013-12-01

Natural hazards, including earthquakes, volcanic eruptions, and tsunamis, have been significant threats to humans throughout recorded history. The Global Positioning System satellites have become primary sensors to measure signatures associated with such natural hazards. These signatures typically include GPS-derived seismic deformation measurements, co-seismic vertical displacements, and real-time GPS-derived ocean buoy positioning estimates. Another way to use GPS observables is to compute the ionospheric total electron content (TEC) to measure and monitor post-seismic ionospheric disturbances caused by earthquakes, volcanic eruptions, and tsunamis. Research at the University of New Brunswick (UNB) laid the foundations to model the three-dimensional ionosphere at NASA's Jet Propulsion Laboratory by ingesting ground- and space-based GPS measurements into the state-of-the-art Global Assimilative Ionosphere Modeling (GAIM) software. As an outcome of the UNB and NASA research, new and innovative GPS applications have been invented including the use of ionospheric measurements to detect tiny fluctuations in the GPS signals between the spacecraft and GPS receivers caused by natural hazards occurring on or near the Earth's surface. This continuing research is expected to provide early warning for tsunamis, earthquakes, volcanic eruptions, and meteor impacts, for example, using GPS and other global navigation satellite systems. We will demonstrate new and upcoming applications including recent natural hazards and artificial explosions that generated TEC perturbations to perform state-of-the-art imaging and modeling of earthquakes, tsunamis and meteor impacts. By studying the propagation properties of ionospheric perturbations generated by natural hazards along with applying sophisticated first-principles physics-based modeling, we are on track to develop new technologies that can potentially save human lives and minimize property damage.

Fault Tolerance Middleware for a Multi-Core System

NASA Technical Reports Server (NTRS)

Some, Raphael R.; Springer, Paul L.; Zima, Hans P.; James, Mark; Wagner, David A.

2012-01-01

Fault Tolerance Middleware (FTM) provides a framework to run on a dedicated core of a multi-core system and handles detection of single-event upsets (SEUs), and the responses to those SEUs, occurring in an application running on multiple cores of the processor. This software was written expressly for a multi-core system and can support different kinds of fault strategies, such as introspection, algorithm-based fault tolerance (ABFT), and triple modular redundancy (TMR). It focuses on providing fault tolerance for the application code, and represents the first step in a plan to eventually include fault tolerance in message passing and the FTM itself. In the multi-core system, the FTM resides on a single, dedicated core, separate from the cores used by the application. This is done in order to isolate the FTM from application faults and to allow it to swap out any application core for a substitute. The structure of the FTM consists of an interface to a fault tolerant strategy module, a responder module, a fault manager module, an error factory, and an error mapper that determines the severity of the error. In the present reference implementation, the only fault tolerant strategy implemented is introspection. The introspection code waits for an application node to send an error notification to it. It then uses the error factory to create an error object, and at this time, a severity level is assigned to the error. The introspection code uses its built-in knowledge base to generate a recommended response to the error. Responses might include ignoring the error, logging it, rolling back the application to a previously saved checkpoint, swapping in a new node to replace a bad one, or restarting the application. The original error and recommended response are passed to the top-level fault manager module, which invokes the response. The responder module also notifies the introspection module of the generated response. This provides additional information to the introspection module that it can use in generating its next response. For example, if the responder triggers an application rollback and errors are still occurring, the introspection module may decide to recommend an application restart.

Automated Flight Dynamics Product Generation for the EOS AM-1 Spacecraft

NASA Technical Reports Server (NTRS)

Matusow, Carla

1999-01-01

As part of NASA's Earth Science Enterprise, the Earth Observing System (EOS) AM-1 spacecraft is designed to monitor long-term, global, environmental changes. Because of the complexity of the AM-1 spacecraft, the mission operations center requires more than 80 distinct flight dynamics products (reports). To create these products, the AM-1 Flight Dynamics Team (FDT) will use a combination of modified commercial software packages (e.g., Analytical Graphic's Satellite ToolKit) and NASA-developed software applications. While providing the most cost-effective solution to meeting the mission requirements, the integration of these software applications raises several operational concerns: (1) Routine product generation requires knowledge of multiple applications executing on variety of hardware platforms. (2) Generating products is a highly interactive process requiring a user to interact with each application multiple times to generate each product. (3) Routine product generation requires several hours to complete. (4) User interaction with each application introduces the potential for errors, since users are required to manually enter filenames and input parameters as well as run applications in the correct sequence. Generating products requires some level of flight dynamics expertise to determine the appropriate inputs and sequencing. To address these issues, the FDT developed an automation software tool called AutoProducts, which runs on a single hardware platform and provides all necessary coordination and communication among the various flight dynamics software applications. AutoProducts, autonomously retrieves necessary files, sequences and executes applications with correct input parameters, and deliver the final flight dynamics products to the appropriate customers. Although AutoProducts will normally generate pre-programmed sets of routine products, its graphical interface allows for easy configuration of customized and one-of-a-kind products. Additionally, AutoProducts has been designed as a mission-independent tool, and can be easily reconfigured to support other missions or incorporate new flight dynamics software packages. After the AM-1 launch, AutoProducts will run automatically at pre-determined time intervals . The AutoProducts tool reduces many of the concerns associated with the flight dynamics product generation. Although AutoProducts required a significant effort to develop because of the complexity of the interfaces involved, its use will provide significant cost savings through reduced operator time and maximum product reliability. In addition, user satisfaction is significantly improved and flight dynamics experts have more time to perform valuable analysis work. This paper will describe the evolution of the AutoProducts tool, highlighting the cost savings and customer satisfaction resulting from its development. It will also provide details about the tool including its graphical interface and operational capabilities.

Portable Device Analyzes Rocks and Minerals

NASA Technical Reports Server (NTRS)

2008-01-01

inXitu Inc., of Mountain View, California, entered into a Phase II SBIR contract with Ames Research Center to develop technologies for the next generation of scientific instruments for materials analysis. The work resulted in a sample handling system that could find a wide range of applications in research and industrial laboratories as a means to load powdered samples for analysis or process control. Potential industries include chemical, cement, inks, pharmaceutical, ceramics, and forensics. Additional applications include characterizing materials that cannot be ground to a fine size, such as explosives and research pharmaceuticals.

Optical coherence tomography in gastroenterology: a review and future outlook

NASA Astrophysics Data System (ADS)

Tsai, Tsung-Han; Leggett, Cadman L.; Trindade, Arvind J.; Sethi, Amrita; Swager, Anne-Fré; Joshi, Virendra; Bergman, Jacques J.; Mashimo, Hiroshi; Nishioka, Norman S.; Namati, Eman

2017-12-01

Optical coherence tomography (OCT) is an imaging technique optically analogous to ultrasound that can generate depth-resolved images with micrometer-scale resolution. Advances in fiber optics and miniaturized actuation technologies allow OCT imaging of the human body and further expand OCT utilization in applications including but not limited to cardiology and gastroenterology. This review article provides an overview of current OCT development and its clinical utility in the gastrointestinal tract, including disease detection/differentiation and endoscopic therapy guidance, as well as a discussion of its future applications.

Eleventh Workshop for Computational Fluid Dynamic Applications in Rocket Propulsion

NASA Technical Reports Server (NTRS)

Williams, R. W. (Compiler)

1993-01-01

Conference publication includes 79 abstracts and presentations and 3 invited presentations given at the Eleventh Workshop for Computational Fluid Dynamic Applications in Rocket Propulsion held at George C. Marshall Space Flight Center, April 20-22, 1993. The purpose of the workshop is to discuss experimental and computational fluid dynamic activities in rocket propulsion. The workshop is an open meeting for government, industry, and academia. A broad number of topics are discussed including computational fluid dynamic methodology, liquid and solid rocket propulsion, turbomachinery, combustion, heat transfer, and grid generation.

Courses without classrooms.

PubMed

Boyer, S A

1999-01-01

There is an alternative to classroom lecture that provides faster, more complete instruction and introduces the learner to clinical application of skills in a safe environment. This teaching style uses multiple media to present professional, published resources that provide excellent quality, topic-specific information. The benefits of this type of teaching/learning module include improved use of student and instructor time, scheduling advantages, increased learning, revenue generation potential, and student empowerment. With this approach, a strong, sound educational base is built, and each course includes some degree or form of clinical application as a key component.

The CST: Its Achievements and Its Connection to the Light Cone

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gross, Franz

since its inception in 1969, I have reviewed applications of the Covariant Spectator Theory (CST). The applications I discuss here include calculations of NN scattering, 3N bound states, electro- magnetic form factors of few-nucleon systems, and the recent successes in describing the dynamical generation of quark mass and the meson spectrum using a chirially invariant quark-antiquark interaction that includes confinement. Furthermore I will discuss the common origin of the Light Cone technique and the CST, which dates back to the 1970's.

The CST: Its Achievements and Its Connection to the Light Cone

DOE PAGES

Gross, Franz

2017-01-19

since its inception in 1969, I have reviewed applications of the Covariant Spectator Theory (CST). The applications I discuss here include calculations of NN scattering, 3N bound states, electro- magnetic form factors of few-nucleon systems, and the recent successes in describing the dynamical generation of quark mass and the meson spectrum using a chirially invariant quark-antiquark interaction that includes confinement. Furthermore I will discuss the common origin of the Light Cone technique and the CST, which dates back to the 1970's.

Eleventh Workshop for Computational Fluid Dynamic Applications in Rocket Propulsion, Part 1

NASA Technical Reports Server (NTRS)

Williams, Robert W. (Compiler)

1993-01-01

Conference publication includes 79 abstracts and presentations given at the Eleventh Workshop for Computational Fluid Dynamic Applications in Rocket Propulsion held at the George C. Marshall Space Flight Center, April 20-22, 1993. The purpose of this workshop is to discuss experimental and computational fluid dynamic activities in rocket propulsion. The workshop is an open meeting for government, industry, and academia. A broad number of topics are discussed including computational fluid dynamic methodology, liquid and solid rocket propulsion, turbomachinery, combustion, heat transfer, and grid generation.

View generated database

NASA Technical Reports Server (NTRS)

Downward, James G.

1992-01-01

This document represents the final report for the View Generated Database (VGD) project, NAS7-1066. It documents the work done on the project up to the point at which all project work was terminated due to lack of project funds. The VGD was to provide the capability to accurately represent any real-world object or scene as a computer model. Such models include both an accurate spatial/geometric representation of surfaces of the object or scene, as well as any surface detail present on the object. Applications of such models are numerous, including acquisition and maintenance of work models for tele-autonomous systems, generation of accurate 3-D geometric/photometric models for various 3-D vision systems, and graphical models for realistic rendering of 3-D scenes via computer graphics.

MICROWAVE-ACCELERATED MULTICOMPONENT REACTIONS UNDER SOLVENT-FREE CONDITIONS

EPA Science Inventory

The application of microwave-accelerated solventless synthetic protocols in multicomponent (MCC) reactions will be exemplified by several condensation and cyclization reactions including the rapid one-pot assembly of valuable heterocyclic compounds from in situ generated intermed...

Plotting equation for gaussian percentiles and a spreadsheet program for generating probability plots

USGS Publications Warehouse

Balsillie, J.H.; Donoghue, J.F.; Butler, K.M.; Koch, J.L.

2002-01-01

Two-dimensional plotting tools can be of invaluable assistance in analytical scientific pursuits, and have been widely used in the analysis and interpretation of sedimentologic data. We consider, in this work, the use of arithmetic probability paper (APP). Most statistical computer applications do not allow for the generation of APP plots, because of apparent intractable nonlinearity of the percentile (or probability) axis of the plot. We have solved this problem by identifying an equation(s) for determining plotting positions of Gaussian percentiles (or probabilities), so that APP plots can easily be computer generated. An EXCEL example is presented, and a programmed, simple-to-use EXCEL application template is hereby made publicly available, whereby a complete granulometric analysis including data listing, moment measure calculations, and frequency and cumulative APP plots, is automatically produced.

The parser generator as a general purpose tool

NASA Technical Reports Server (NTRS)

Noonan, R. E.; Collins, W. R.

1985-01-01

The parser generator has proven to be an extremely useful, general purpose tool. It can be used effectively by programmers having only a knowledge of grammars and no training at all in the theory of formal parsing. Some of the application areas for which a table-driven parser can be used include interactive, query languages, menu systems, translators, and programming support tools. Each of these is illustrated by an example grammar.

An algorithm for generating all possible 2(p-q) fractional factorial designs and its use in scientific experimentation

NASA Technical Reports Server (NTRS)

Sidik, S. M.

1973-01-01

An algorithm and computer program are presented for generating all the distinct 2(p-q) fractional factorial designs. Some applications of this algorithm to the construction of tables of designs and of designs for nonstandard situations and its use in Bayesian design are discussed. An appendix includes a discussion of an actual experiment whose design was facilitated by the algorithm.

Electric power generation using geothermal brine resources for a proof of concept facility

NASA Technical Reports Server (NTRS)

Hankin, J. W.

1974-01-01

An exploratory systems study of a geothermal proof-of-concept facility is being conducted. This study is the initial phase (Phase 0) of a project to establish the technical and economic feasibility of using hot brine resources for electric power production and other industrial applications. Phase 0 includes the conceptual design of an experimental test-bed facility and a 10-MWe power generating facility.

Photoaligning and photopatterning technology: applications in displays and photonics

NASA Astrophysics Data System (ADS)

Chigrinov, Vladimir

2016-03-01

The advantages of LC photoalignment technology in comparison with common "rubbing" alignment methods tend to the continuation of the research in this field. Almost all the criteria of perfect LC alignment are met in case of azo-dye layers. Nowadays azo-dye alignment materials can be already used in LCD manufacturing, e.g. for the alignment of monomers in LCP films for new generations of photonics and optics devices. Recently the new application of photoaligned technology for the tunable LC lenses with a variable focal distance was proposed. New optically rewritable (ORW) liquid crystal display and photonics devices with a light controllable structure may include LC E-paper screens, LC lenses with a variable focal distance etc. Fast ferroelectric liquid crystal devices (FLCD) are achieved through the application of nano-scale photo aligning (PA) layers in FLC cells. The novel photoaligned FLC devices may include field sequential color (FSC) FLC with a high resolution, high brightness, low power consumption and extended color gamut to be used for PCs, PDAs, switchable goggles, and new generation of switchable 2D/3D LCD TVs, as well as photonics elements.

Control system and method for a hybrid electric vehicle

DOEpatents

Tamor, Michael Alan

2001-03-06

Several control methods are presented for application in a hybrid electric vehicle powertrain including in various embodiments an engine, a motor/generator, a transmission coupled at an input thereof to receive torque from the engine and the motor generator coupled to augment torque provided by the engine, an energy storage device coupled to receive energy from and provide energy to the motor/generator, an engine controller (EEC) coupled to control the engine, a transmission controller (TCM) coupled to control the transmission and a vehicle system controller (VSC) adapted to control the powertrain.

EDITORIAL: Special issue for papers selected from The 8th International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications (PowerMEMS 2008) Special issue for papers selected from The 8th International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications (PowerMEMS 2008)

NASA Astrophysics Data System (ADS)

Tanaka, Shuji

2009-09-01

This special issue of the Journal of Micromechanics and Microengineering features papers selected from The 8th International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications (PowerMEMS 2008) with the 2nd Symposium on Micro Environmental Machine Systems (μMEMS 2008). The workshop was held in Sendai, Japan on 9-12 November 2008 by Tohoku University. This is the second time that the PowerMEMS workshop has been held in Sendai, following the first workshop in 2000. Power MEMS is one of the newest categories of MEMS, which encompasses microdevices and microsystems for power generation, energy conversion and propulsion. The first concept of Power MEMS was born in the late 1990's from a MEMS-based gas turbine project at Massachusetts Institute of Technology. After that, the research and development of Power MEMS have been promoted by the strong need for compact power sources with high energy and/or power density. Since its inception, Power MEMS has expanded to include not only various MEMS-based power generators but also small energy machines and microdevices for macro power generators. Previously, the main topics of the PowerMEMS workshop were miniaturized gas turbines and micro fuel cells, but recently, energy harvesting has been the hottest topic. In 2008, energy harvesting had a 41% share in the 118 accepted regular papers. This special issue includes 19 papers on various topics. Finally, I would like to express my sincere appreciation to the members of the International Steering Committee, the Technical Program Committee, the Local Organizing Committee and financial supporters. This special issue was edited in collaboration with the staff of IOP Publishing.

Double lens device for tunable harmonic generation of laser beams in KBBF/RBBF crystals or other non-linear optic materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaminski, Adam

A method and apparatus to generate harmonically related laser wavelengths includes a pair of lenses at opposing faces of a non-linear optical material. The lenses are configured to promote incoming and outgoing beams to be normal to each outer lens surface over a range of acceptance angles of the incoming laser beam. This reduces reflection loss for higher efficiency operation. Additionally, the lenses allow a wider range of wavelengths for lasers for more universal application. Examples of the lenses include plano-cylindrical and plano-spherical form factors.

Giant gain from spontaneously generated coherence in Y-type double quantum dot structure

NASA Astrophysics Data System (ADS)

Al-Nashy, B.; Razzaghi, Sonia; Al-Musawi, Muwaffaq Abdullah; Rasooli Saghai, H.; Al-Khursan, Amin H.

A theoretical model was presented for linear susceptibility using density matrix theory for Y-configuration of double quantum dots (QDs) system including spontaneously generated coherence (SGC). Two SGC components are included for this system: V, and Λ subsystems. It is shown that at high V-component, the system have a giga gain. At low Λ-system component; it is possible to controls the light speed between superluminal and subluminal using one parameter by increasing SGC component of the V-system. This have applications in quantum information storage and spatially-varying temporal clock.

Spacecraft Power Systems Engineering: Solutions for NASA's Manned Space Program

NASA Technical Reports Server (NTRS)

Scott, John H.

2007-01-01

An overview of spacecraft power systems is presented, with a focus on applications in the manned space program. The topics include: 1) History; 2) State-of-the-art; 3) Development directions; 4) Focus on applications in the manned space program led from JSC; 5) Power Systems Engineering Trade Space; 6) Power Generation and Energy Storage; 7) Power Distribution and Control; and 8) Actuation

Holography: A survey

NASA Technical Reports Server (NTRS)

Dudley, D. D.

1973-01-01

The development of holography and the state of the art in recording and displaying information, microscopy, motion, pictures, and television applications are discussed. In addition to optical holography, information is presented on microwave, acoustic, ultrasonic, and seismic holography. Other subjects include data processing, data storage, pattern recognition, and computer-generated holography. Diagrams of holographic installations are provided. Photographs of typical holographic applications are used to support the theoretical aspects.

DataPlus™ - a revolutionary applications generator for DOS hand-held computers

Treesearch

David Dean; Linda Dean

2000-01-01

DataPlus allows the user to easily design data collection templates for DOS-based hand-held computers that mimic clipboard data sheets. The user designs and tests the application on the desktop PC and then transfers it to a DOS field computer. Other features include: error checking, missing data checks, and sensor input from RS-232 devices such as bar code wands,...

Manufacturing process applications team (MATeam)

NASA Technical Reports Server (NTRS)

Bangs, E. R.

1980-01-01

The objectives and activities of an aerospace technology transfer group are outlined and programs in various stages of progress are described including the orbital tube flaring device, infrared proximity sensor for robot positioning, laser stripping magnet wire, infrared imaging as welding process tracking system, carbide coating of cutting tools, nondestructive fracture toughness testing of titanium welds, portable solar system for agricultural applications, and an anerobic methane gas generator.

Cyclotron maser instability and its applications

NASA Astrophysics Data System (ADS)

Wu, C. S.

The possible application of cyclotron maser theory to a variety of radio sources is considered, with special attention given to the theory of auroral kilometric radiation (AKR) of Wu and Lee (1979). The AKR model assumes a loss-cone distribution function for the reflected electrons, along with the depletion of low-energy electrons by the parallel electric field. Other topics considered include fundamental AKR, second-harmonic AKR, the generation of Z-mode radiation, and the application of maser instability to other sources than AKR.

Applicator modeling for electromagnetic thermotherapy of cervix cancer.

PubMed

Rezaeealam, Behrooz

2015-03-01

This report proposes an induction heating coil design that can be used for producing strong magnetic fields around ferromagnetic implants located in the cervix of uterus. The effect of coil design on the uniformity and extent of heat generation ability is inspected. Also, a numerical model of the applicator is developed that includes the ferromagnetic implants, and is coupled to the bioheat transfer model of the body tissue. Then, the ability of the proposed applicator for electromagnetic thermotherapy is investigated.

Method and Apparatus for Generating Flight-Optimizing Trajectories

NASA Technical Reports Server (NTRS)

Ballin, Mark G. (Inventor); Wing, David J. (Inventor)

2015-01-01

An apparatus for generating flight-optimizing trajectories for a first aircraft includes a receiver capable of receiving second trajectory information associated with at least one second aircraft. The apparatus also includes a traffic aware planner (TAP) module operably connected to the receiver to receive the second trajectory information. The apparatus also includes at least one internal input device on board the first aircraft to receive first trajectory information associated with the first aircraft and a TAP application capable of calculating an optimal trajectory for the first aircraft based at least on the first trajectory information and the second trajectory information. The optimal trajectory at least avoids conflicts between the first trajectory information and the second trajectory information.

SAW Synthesis With IDTs Array and the Inverse Filter: Toward a Versatile SAW Toolbox for Microfluidics and Biological Applications.

PubMed

Riaud, Antoine; Baudoin, Michael; Thomas, Jean-Louis; Bou Matar, Olivier

2016-10-01

Surface acoustic waves (SAWs) are versatile tools to manipulate fluids at small scales for microfluidics and biological applications. A nonexhaustive list of operations that can be performed with SAW includes sessile droplet displacement, atomization, division, and merging but also the actuation of fluids embedded in microchannels or the manipulation of suspended particles. However, each of these operations requires a specific design of the wave generation system, the so-called interdigitated transducers (IDTs). Depending on the application, it might indeed be necessary to generate focused or plane, propagating or standing, and aligned or shifted waves. Furthermore, the possibilities offered by more complex wave fields such as acoustical vortices for particle tweezing and liquid twisting cannot be explored with classical IDTs. In this paper, we show that the inverse filter technique coupled with an IDTs array enables us to synthesize all classical wave fields used in microfluidics and biological applications with a single multifunctional platform. It also enables us to generate swirling SAWs, whose potential for the on-chip synthesis of tailored acoustical vortices has been demonstrated lately. The possibilities offered by this platform are illustrated by performing many operations successively on sessile droplets with the same system.

Multipurpose neutron generators based on the radio frequency quadrupole linear accelerator

NASA Astrophysics Data System (ADS)

Hamm, Robert W.

2000-12-01

Neutron generators based on the Radio Frequency Quadrupole accelerator are now used for a variety of applications. These compact linear accelerators can produce from 108 to more than 1013 neutrons/second using either proton or deuteron beams to bombard beryllium targets. They exhibit long lifetimes at full output, as there is little target or beam degradation. Since they do not use radioactive materials, licensing requirements are less stringent than for isotopic sources or tritium sealed tube generators. The light weight and compact size of these robust systems make them transportable. The low divergence output beam from the RFQ also allows use of a remote target, which can reduce the seize of the shielding and moderator. The RFQ linac can be designed with a wide range of output beam energy and used with other targets such as lithium and deuterium to produce a neutron spectrum tailored to a specific application. These pulsed systems are well-suited for applications requiring a high peak neutron flux, including activation analysis of very short-lived reaction products. They can replace conventional sources in non-destructive testing applications such as thermal or fast neutron radiography, and can also be used for cancer therapy.

PROCESS HEAT GENERATION AND CONSUMPTION, 1939 TO 1967

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prehn, W.L. Jr.; Tarrice, R.R.

A survey and analysis of the generation and use of heat in manufacturing has been completed. The greatest emphasis has been placed on the variety of heat applications in United States manufacturing industries with some discussion of other important uses. The generation of electricity is excluded from this analysis. The generation of heat through steam production and through directfiring means is analyzed and described in terms of the major economic factors dictating application and possible growth. These factors include: geography, fuel, industry growth, cost, heat quality, generating unit size, and other contributing elements. Some data are given on similar mattersmore » in foreign countries. Only those countries which are important in terms of industrial activity are considered. A projection of demand for industrial heat in the categories studied is shown for the next five years and the next ten years. It is concluded that certain portions of the industrial complex of the world are sufficiently important in terms of the use of heat that further detailed study of the above factors is well justified. (auth)« less

Method and apparatus for passive optical dosimeter comprising caged dye molecules

DOEpatents

Sandison, David R.

2001-07-03

A new class of ultraviolet dosimeters is made possible by exposing caged dye molecules, which generate a dye molecule on exposure to ultraviolet radiation, to an exterior environment. Applications include sunburn monitors, characterizing the UV exposure history of UV-sensitive materials, especially including structural plastics, and use in disposable `one-use` optical equipment, especially medical devices.

Ultra-short wavelength x-ray system

DOEpatents

Umstadter, Donald [Ann Arbor, MI; He, Fei [Ann Arbor, MI; Lau, Yue-Ying [Potomac, MD

2008-01-22

A method and apparatus to generate a beam of coherent light including x-rays or XUV by colliding a high-intensity laser pulse with an electron beam that is accelerated by a synchronized laser pulse. Applications include x-ray and EUV lithography, protein structural analysis, plasma diagnostics, x-ray diffraction, crack analysis, non-destructive testing, surface science and ultrafast science.

Generating structured light with phase helix and intensity helix using reflection-enhanced plasmonic metasurface at 2 μm

NASA Astrophysics Data System (ADS)

Zhao, Yifan; Du, Jing; Zhang, Jinrun; Shen, Li; Wang, Jian

2018-04-01

Mid-infrared (2-20 μm) light has been attracting great attention in many areas of science and technology. Beyond the extended wavelength range from visible and near-infrared to mid-infrared, shaping spatial structures may add opportunities to grooming applications of mid-infrared photonics. Here, we design and fabricate a reflection-enhanced plasmonic metasurface and demonstrate efficient generation of structured light with the phase helix and intensity helix at 2 μm. This work includes two distinct aspects. First, structured light (phase helix, intensity helix) generation at 2 μm, which is far beyond the ability of conventional spatial light modulators, is enabled by the metasurface with sub-wavelength engineered structures. Second, the self-referenced intensity helix against environmental noise is generated without using a spatially separated light. The demonstrations may open up advanced perspectives to structured light applications at 2 μm, such as phase helix for communications and non-communications (imaging, sensing) and intensity helix for enhanced microscopy and advanced metrology.

Molecular electronics: The technology of sixth generation computers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jarvis, M.T.; Miller, R.K.

1987-01-01

In February 1986, Japan began the 6th Generation project. At the 1987 Economic Summit in Venice, Prime Minister Yashuhiro Makasone opened the project to world collaboration. A project director suggests that the 6th Generation ''may just be a turning point for human society.'' The major rationale for building molecular electronic devices is to achieve advances in computational densities and speeds. Proposed chromophore chains for molecular-scale chips, for example, could be spaced closer than today's silicone elements by a factor of almost 100. This book describes the research and proposed designs for molecular electronic devices and computers. It examines specific potentialmore » applications and the relationship to molecular electronics to silicon technology and presents the first published survey of experts on research issues, applications, and forecast of future developments and also includes market forecast. An interesting suggestion of the survey is that the chemical industry may become a significant factor in the computer industry as the sixth generation unfolds.« less

Internal combustion engine report: Spark ignited ICE GenSet optimization and novel concept development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keller, J.; Blarigan, P. Van

1998-08-01

In this manuscript the authors report on two projects each of which the goal is to produce cost effective hydrogen utilization technologies. These projects are: (1) the development of an electrical generation system using a conventional four-stroke spark-ignited internal combustion engine generator combination (SI-GenSet) optimized for maximum efficiency and minimum emissions, and (2) the development of a novel internal combustion engine concept. The SI-GenSet will be optimized to run on either hydrogen or hydrogen-blends. The novel concept seeks to develop an engine that optimizes the Otto cycle in a free piston configuration while minimizing all emissions. To this end themore » authors are developing a rapid combustion homogeneous charge compression ignition (HCCI) engine using a linear alternator for both power take-off and engine control. Targeted applications include stationary electrical power generation, stationary shaft power generation, hybrid vehicles, and nearly any other application now being accomplished with internal combustion engines.« less

Automated, Parametric Geometry Modeling and Grid Generation for Turbomachinery Applications

NASA Technical Reports Server (NTRS)

Harrand, Vincent J.; Uchitel, Vadim G.; Whitmire, John B.

2000-01-01

The objective of this Phase I project is to develop a highly automated software system for rapid geometry modeling and grid generation for turbomachinery applications. The proposed system features a graphical user interface for interactive control, a direct interface to commercial CAD/PDM systems, support for IGES geometry output, and a scripting capability for obtaining a high level of automation and end-user customization of the tool. The developed system is fully parametric and highly automated, and, therefore, significantly reduces the turnaround time for 3D geometry modeling, grid generation and model setup. This facilitates design environments in which a large number of cases need to be generated, such as for parametric analysis and design optimization of turbomachinery equipment. In Phase I we have successfully demonstrated the feasibility of the approach. The system has been tested on a wide variety of turbomachinery geometries, including several impellers and a multi stage rotor-stator combination. In Phase II, we plan to integrate the developed system with turbomachinery design software and with commercial CAD/PDM software.

Transformational leadership to promote cross-generational retention.

PubMed

Lobo, Vanessa M

2010-05-01

As the current nursing shortage intensifies under the weight of an aging population, retention of front-line staff is becoming paramount. Studies have consistently demonstrated that the leadership style of nurse managers plays a significant role to this end. This paper describes some of the challenges that managers encounter in their dealings with the contemporary multigenerational workforce - including the baby boomers, generation X and generation Y (the "millennials"). A review of research findings suggests the insufficiency of a single leadership approach to nurse management compared to more tailored generational strategies. Application of the transformational leadership model provides the background and tenets from which solutions are proposed for multigenerational management.

The Geostationary Operational Environmental Satellite (GOES) Product Generation System

NASA Technical Reports Server (NTRS)

Haines, S. L.; Suggs, R. J.; Jedlovec, G. J.

2004-01-01

The Geostationary Operational Environmental Satellite (GOES) Product Generation System (GPGS) is introduced and described. GPGS is a set of computer programs developed and maintained at the Global Hydrology and Climate Center and is designed to generate meteorological data products using visible and infrared measurements from the GOES-East Imager and Sounder instruments. The products that are produced by GPGS are skin temperature, total precipitable water, cloud top pressure, cloud albedo, surface albedo, and surface insolation. A robust cloud mask is also generated. The retrieval methodology for each product is described to include algorithm descriptions and required inputs and outputs for the programs. Validation is supplied where applicable.

Femtosecond laser beam propagation through corneal tissue: Evaluation of therapeutic laser-stimulated second and third- harmonic generation

NASA Astrophysics Data System (ADS)

Calhoun, William R., III

One of the most recent advancements in laser technology is the development of ultrashort pulsed femtosecond lasers (FSLs). FSLs are improving many fields due to their unique extreme precision, low energy and ablation characteristics. In the area of laser medicine, ophthalmic surgeries have seen very promising developments. Some of the most commonly performed surgical operations in the world, including laser-assisted in-situ keratomileusis (LASIK), lens replacement (cataract surgery), and keratoplasty (cornea transplant), now employ FSLs for their unique abilities that lead to improved clinical outcome and patient satisfaction. The application of FSLs in medical therapeutics is a recent development, and although they offer many benefits, FSLs also stimulate nonlinear optical effects (NOEs), many of which were insignificant with previously developed lasers. NOEs can change the laser characteristics during propagation through a medium, which can subsequently introduce unique safety concerns for the surrounding tissues. Traditional approaches for characterizing optical effects, laser performance, safety and efficacy do not properly account for NOEs, and there remains a lack of data that describe NOEs in clinically relevant procedures and tissues. As FSL technology continues to expand towards new applications, FSL induced NOEs need to be better understood in order to ensure safety as FSL medical devices and applications continue to evolve at a rapid pace. In order to improve the understanding of FSL-tissue interactions related to NOEs stimulated during laser beam propagation though corneal tissue, research investigations were conducted to evaluate corneal optical properties and determine how corneal tissue properties including corneal layer, collagen orientation and collagen crosslinking, and laser parameters including pulse energy, repetition rate and numerical aperture affect second and third-harmonic generation (HG) intensity, duration and efficiency. The results of these studies revealed that all laser parameters and tissue properties had a substantial influence on HG. The dynamic relationship between optical breakdown and HG was responsible for many observed changes in HG metrics. The results also demonstrated that the new generation of therapeutic FSLs has the potential to generate hazardous effects if not carefully controlled. Finally, recommendations are made to optimize current and guide future FSL applications.

Implementation Guidance for the Next Generation Leaching Tests

EPA Science Inventory

Poster provides an overview of the purpose and utility of this research, highlights of the research to support the Leaching Environmental Assessment Framework (LEAF), application and translation (including data management and analysis software), intended end users, and lessons le...

Best Practices in Overset Grid Generation

NASA Technical Reports Server (NTRS)

Gomez, Reynaldo J., III

2002-01-01

Accurate geometry + high quality grids are necessary for an accurate solution. Other requirements include a) Verified/validated solver with appropriate physics b) Convergence criteria consistent with application: 1) Aerodynamics - forces and moments; 2) Heat transfer - maximum and minimum heat transfer coefficients.

29 CFR 1926.402 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... subpart V of this part for the construction of power distribution and transmission lines. ... electrical equipment and installations used to provide electric power and light at the jobsite. These... installations used for the generation, transmission, and distribution of electric energy, including related...

29 CFR 1926.402 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... subpart V of this part for the construction of power distribution and transmission lines. ... electrical equipment and installations used to provide electric power and light at the jobsite. These... installations used for the generation, transmission, and distribution of electric energy, including related...

MICROWAVE-FACILITATED MULTICOMPONENT REACTIONS UNDER SOLVENT-FREE CONDITIONS

EPA Science Inventory

The application of microwave-expedited solvent-free synthetic protocols in multi-component (MCC) reactions will be exemplified by several condensation and cyclization reactions including the rapid one-pot assembly of heterocyclic compounds from in situ generated intermediates. R...

29 CFR 1926.402 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... installations used for the generation, transmission, and distribution of electric energy, including related...) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Electrical Installation Safety Requirements § 1926.402... electrical equipment and installations used to provide electric power and light at the jobsite. These...

29 CFR 1926.402 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... installations used for the generation, transmission, and distribution of electric energy, including related...) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Electrical Installation Safety Requirements § 1926.402... electrical equipment and installations used to provide electric power and light at the jobsite. These...

ME science as mobile learning based on virtual reality

NASA Astrophysics Data System (ADS)

Fradika, H. D.; Surjono, H. D.

2018-04-01

The purpose of this article described about ME Science (Mobile Education Science) as mobile learning application learning of Fisika Inti. ME Science is a product of research and development (R&D) that was using Alessi and Trollip model. Alessi and Trollip model consists three stages that are: (a) planning include analysis of problems, goals, need, and idea of development product, (b) designing includes collecting of materials, designing of material content, creating of story board, evaluating and review product, (c) developing includes development of product, alpha testing, revision of product, validation of product, beta testing, and evaluation of product. The article describes ME Science only to development of product which include development stages. The result of development product has been generates mobile learning application based on virtual reality that can be run on android-based smartphone. These application consist a brief description of learning material, quizzes, video of material summery, and learning material based on virtual reality.

Recent applications of the transonic wing analysis computer code, TWING

NASA Technical Reports Server (NTRS)

Subramanian, N. R.; Holst, T. L.; Thomas, S. D.

1982-01-01

An evaluation of the transonic-wing-analysis computer code TWING is given. TWING utilizes a fully implicit approximate factorization iteration scheme to solve the full potential equation in conservative form. A numerical elliptic-solver grid-generation scheme is used to generate the required finite-difference mesh. Several wing configurations were analyzed, and the limits of applicability of this code was evaluated. Comparisons of computed results were made with available experimental data. Results indicate that the code is robust, accurate (when significant viscous effects are not present), and efficient. TWING generally produces solutions an order of magnitude faster than other conservative full potential codes using successive-line overrelaxation. The present method is applicable to a wide range of isolated wing configurations including high-aspect-ratio transport wings and low-aspect-ratio, high-sweep, fighter configurations.

Recent GRC Aerospace Technologies Applicable to Terrestrial Energy Systems

NASA Technical Reports Server (NTRS)

Kankam, David; Lyons, Valerie J.; Hoberecht, Mark A.; Tacina, Robert R.; Hepp, Aloysius F.

2000-01-01

This paper is an overview of a wide range of recent aerospace technologies under development at the NASA Glenn Research Center, in collaboration with other NASA centers, government agencies, industry and academia. The focused areas are space solar power, advanced power management and distribution systems, Stirling cycle conversion systems, fuel cells, advanced thin film photovoltaics and batteries, and combustion technologies. The aerospace-related objectives of the technologies are generation of space power, development of cost-effective and reliable, high performance power systems, cryogenic applications, energy storage, and reduction in gas-turbine emissions, with attendant clean jet engines. The terrestrial energy applications of the technologies include augmentation of bulk power in ground power distribution systems, and generation of residential, commercial and remote power, as well as promotion of pollution-free environment via reduction in combustion emissions.

Laser-powered MHD generators for space application

NASA Technical Reports Server (NTRS)

Jalufka, N. W.

1986-01-01

Magnetohydrodynamic (MHD) energy conversion systems of the pulsed laser-supported detonation (LSD) wave, plasma MHD, and liquid-metal MHD (LMMHD) types are assessed for their potential as space-based laser-to-electrical power converters. These systems offer several advantages as energy converters relative to the present chemical, nuclear, and solar devices, including high conversion efficiency, simple design, high-temperature operation, high power density, and high reliability. Of these systems, the Brayton cycle liquid-metal MHD system appears to be the most attractive. The LMMHD technology base is well established for terrestrial applications, particularly with regard to the generator, mixer, and other system components. However, further research is required to extend this technology base to space applications and to establish the technology required to couple the laser energy into the system most efficiently. Continued research on each of the three system types is recommended.

Integrated Power/Attitude Control System (IPACS) study. Volume 1: Feasibility studies. [application of flywheels for power storage and generation

NASA Technical Reports Server (NTRS)

Notti, J. E.; Cormack, A., III; Schmill, W. C.

1974-01-01

An Integrated Power/Attitude Control System (IPACS) concept consisting of an array of spinning flywheels, with or without gimbals, capable of performing the dual function of power storage and generation, as well as attitude control has been investigated. This system provides attitude control through momentum storage, and replaces the storage batteries onboard the spacecraft. The results of the investigation are presented in two volumes. The trade-off studies performed to establish the feasibility, cost effectiveness, required level of development, and boundaries of application of IPACS to a wide variety of spacecraft are discussed. The conceptual designs for a free-flying research application module (RAM), and for a tracking and data relay satellite (TDRS) are presented. Results from dynamic analyses and simulations of the IPACS conceptual designs are included.

Application of Hydrodynamic Cavitation for Food and Bioprocessing

NASA Astrophysics Data System (ADS)

Gogate, Parag R.

Hydrodynamic cavitation can be simply generated by the alterations in the flow field in high speed/high pressure devices and also by passage of the liquid through a constriction such as orifice plate, venturi, or throttling valve. Hydrodynamic cavitation results in the formation of local hot spots, release of highly reactive free radicals, and enhanced mass transfer rates due to turbulence generated as a result of liquid circulation currents. These conditions can be suitably applied for intensification of different bioprocessing applications in an energy-efficient manner as compared to conventionally used ultrasound-based reactors. The current chapter aims at highlighting different aspects related to hydrodynamic cavitation, including the theoretical aspects for optimization of operating parameters, reactor designs, and overview of applications relevant to food and bioprocessing. Some case studies highlighting the comparison of hydrodynamic cavitation and acoustic cavitation reactors will also be discussed.

Application of Next-generation Sequencing Technology in Forensic Science

PubMed Central

Yang, Yaran; Xie, Bingbing; Yan, Jiangwei

2014-01-01

Next-generation sequencing (NGS) technology, with its high-throughput capacity and low cost, has developed rapidly in recent years and become an important analytical tool for many genomics researchers. New opportunities in the research domain of the forensic studies emerge by harnessing the power of NGS technology, which can be applied to simultaneously analyzing multiple loci of forensic interest in different genetic contexts, such as autosomes, mitochondrial and sex chromosomes. Furthermore, NGS technology can also have potential applications in many other aspects of research. These include DNA database construction, ancestry and phenotypic inference, monozygotic twin studies, body fluid and species identification, and forensic animal, plant and microbiological analyses. Here we review the application of NGS technology in the field of forensic science with the aim of providing a reference for future forensics studies and practice. PMID:25462152

Band excitation method applicable to scanning probe microscopy

DOEpatents

Jesse, Stephen [Knoxville, TN; Kalinin, Sergei V [Knoxville, TN

2010-08-17

Methods and apparatus are described for scanning probe microscopy. A method includes generating a band excitation (BE) signal having finite and predefined amplitude and phase spectrum in at least a first predefined frequency band; exciting a probe using the band excitation signal; obtaining data by measuring a response of the probe in at least a second predefined frequency band; and extracting at least one relevant dynamic parameter of the response of the probe in a predefined range including analyzing the obtained data. The BE signal can be synthesized prior to imaging (static band excitation), or adjusted at each pixel or spectroscopy step to accommodate changes in sample properties (adaptive band excitation). An apparatus includes a band excitation signal generator; a probe coupled to the band excitation signal generator; a detector coupled to the probe; and a relevant dynamic parameter extractor component coupled to the detector, the relevant dynamic parameter extractor including a processor that performs a mathematical transform selected from the group consisting of an integral transform and a discrete transform.

Band excitation method applicable to scanning probe microscopy

DOEpatents

Jesse, Stephen; Kalinin, Sergei V

2013-05-28

Methods and apparatus are described for scanning probe microscopy. A method includes generating a band excitation (BE) signal having finite and predefined amplitude and phase spectrum in at least a first predefined frequency band; exciting a probe using the band excitation signal; obtaining data by measuring a response of the probe in at least a second predefined frequency band; and extracting at least one relevant dynamic parameter of the response of the probe in a predefined range including analyzing the obtained data. The BE signal can be synthesized prior to imaging (static band excitation), or adjusted at each pixel or spectroscopy step to accommodate changes in sample properties (adaptive band excitation). An apparatus includes a band excitation signal generator; a probe coupled to the band excitation signal generator; a detector coupled to the probe; and a relevant dynamic parameter extractor component coupled to the detector, the relevant dynamic parameter extractor including a processor that performs a mathematical transform selected from the group consisting of an integral transform and a discrete transform.

Numerical grid generation in computational field simulations. Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soni, B.K.; Thompson, J.F.; Haeuser, J.

1996-12-31

To enhance the CFS technology to its next level of applicability (i.e., to create acceptance of CFS in an integrated product and process development involving multidisciplinary optimization) the basic requirements are: rapid turn-around time, reliable and accurate simulation, affordability and appropriate linkage to other engineering disciplines. In response to this demand, there has been a considerable growth in the grid generation related research activities involving automization, parallel processing, linkage with the CAD-CAM systems, CFS with dynamic motion and moving boundaries, strategies and algorithms associated with multi-block structured, unstructured, hybrid, hexahedral, and Cartesian grids, along with its applicability to various disciplinesmore » including biomedical, semiconductor, geophysical, ocean modeling, and multidisciplinary optimization.« less

Proceedings of the American Power Conference. Volume 58-I

DOE Office of Scientific and Technical Information (OSTI.GOV)

McBride, A.E.

1996-10-01

This is volume 58-I of the proceedings of the American Power Conference, 1996, Technology for Competition and Globalization. The topics of the papers include power plant DC issues; cost of environmental compliance; advanced coal systems -- environmental performance; technology for competition in dispersed generation; superconductivity technologies for electric utility applications; power generation trends and challenges in China; aging in nuclear power plants; innovative and competitive repowering options; structural examinations, modifications and repairs; electric load forecasting; distribution planning; EMF effects; fuzzy logic and neural networks for power plant applications; electrokinetic decontamination of soils; integrated gasification combined cycle; advances in fusion; coolingmore » towers; relays; plant controls; flue gas desulfurization; waste product utilization; and improved technologies.« less

Evaluating opportunities to improve material and energy impacts in commodity supply chains

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanes, Rebecca J.; Carpenter, Alberta

When evaluated at the scale of individual processes, next-generation technologies may be more energy and emissions intensive than current technology. Furthermore, many advanced technologies have the potential to reduce material and energy consumption in upstream or downstream processing stages. In order to fully understand the benefits and consequences of technology deployment, next-generation technologies should be evaluated in context, as part of a supply chain. This work presents the Materials Flow through Industry (MFI) supply chain modeling tool. The MFI tool is a cradle-to-gate linear network model of the US industrial sector that can model a wide range of manufacturing scenarios,more » including changes in production technology and increases in industrial energy efficiency. The MFI tool was developed to perform supply chain scale analyses in order to quantify the impacts and benefits of next-generation technologies and materials at that scale. For the analysis presented in this paper, the MFI tool is utilized to explore a case study comparing three lightweight vehicle supply chains to the supply chain of a conventional, standard weight vehicle. Several of the lightweight vehicle supply chains are evaluated under manufacturing scenarios that include next-generation production technologies and next-generation materials. Results indicate that producing lightweight vehicles is more energy and emission intensive than producing the non-lightweight vehicle, but the fuel saved during vehicle use offsets this increase. In this case study, greater reductions in supply chain energy and emissions were achieved through the application of the next-generation technologies than from application of energy efficiency increases.« less

Evaluating opportunities to improve material and energy impacts in commodity supply chains

DOE PAGES

Hanes, Rebecca J.; Carpenter, Alberta

2017-01-10

When evaluated at the scale of individual processes, next-generation technologies may be more energy and emissions intensive than current technology. Furthermore, many advanced technologies have the potential to reduce material and energy consumption in upstream or downstream processing stages. In order to fully understand the benefits and consequences of technology deployment, next-generation technologies should be evaluated in context, as part of a supply chain. This work presents the Materials Flow through Industry (MFI) supply chain modeling tool. The MFI tool is a cradle-to-gate linear network model of the US industrial sector that can model a wide range of manufacturing scenarios,more » including changes in production technology and increases in industrial energy efficiency. The MFI tool was developed to perform supply chain scale analyses in order to quantify the impacts and benefits of next-generation technologies and materials at that scale. For the analysis presented in this paper, the MFI tool is utilized to explore a case study comparing three lightweight vehicle supply chains to the supply chain of a conventional, standard weight vehicle. Several of the lightweight vehicle supply chains are evaluated under manufacturing scenarios that include next-generation production technologies and next-generation materials. Results indicate that producing lightweight vehicles is more energy and emission intensive than producing the non-lightweight vehicle, but the fuel saved during vehicle use offsets this increase. In this case study, greater reductions in supply chain energy and emissions were achieved through the application of the next-generation technologies than from application of energy efficiency increases.« less

New class of optoelectronic oscillators (OEO) for microwave signal generation and processing

NASA Astrophysics Data System (ADS)

Maleki, Lute; Yao, X. S.

1996-11-01

A new class of oscillators based on photonic devices is presented. These opto-electronic oscillators (OEO's) generate microwave oscillation by converting continuous energy from a light source using a feedback circuit which includes a delay element, an electro-optic switch, and a photodetector. Different configurations of OEO's are presented, each of which may be applied to a particular application requiring ultra-high performance, or low cost and small size.

Application of a Resilience Framework to Military Installations: A Methodology for Energy Resilience Business Case Decisions

DTIC Science & Technology

2016-10-04

analysis (due to site-level evaluations), but could be added in the future, include: wind turbines (the installations we visited were not interested due...procurement, operation, maintenance , testing, and fueling of the generators, detailed inventory and cost data is difficult to obtain. The DPW is often...understaffed, leading to uneven testing and maintenance of the equipment despite their best efforts. The reliability of these generators is typically

Anisotropic conducting films for electromagnetic radiation applications

DOEpatents

Cavallo, Francesca; Lagally, Max G.; Rojas-Delgado, Richard

2015-06-16

Electronic devices for the generation of electromagnetic radiation are provided. Also provided are methods for using the devices to generate electromagnetic radiation. The radiation sources include an anisotropic electrically conducting thin film that is characterized by a periodically varying charge carrier mobility in the plane of the film. The periodic variation in carrier mobility gives rise to a spatially varying electric field, which produces electromagnetic radiation as charged particles pass through the film.

Surface grid generation for complex three-dimensional geometries

NASA Technical Reports Server (NTRS)

Luh, Raymond Ching-Chung

1988-01-01

An outline is presented for the creation of surface grids from primitive geometry data such as obtained from CAD/CAM systems. The general procedure is applicable to any geometry including full aircraft with wing, nacelle, and empennage. When developed in an interactive graphics environment, a code based on this procedure is expected to substantially improve the turn around time for generating surface grids on complex geometries. Results are shown for a general hypersonic airplane geometry.

Surface grid generation for complex three-dimensional geometries

NASA Technical Reports Server (NTRS)

Luh, Raymond Ching-Chung

1988-01-01

An outline is presented for the creation of surface grids from primitive geometry data such as obtained from CAD/CAM systems. The general procedure is applicable to any geometry including full aircraft with wing, nacelle, and empennage. When developed in an interactive graphics environment, a code base on this procedure is expected to substantially improve the turn around time for generating surface grids on complex geometries. Results are shown for a general hypersonic airplane geometry.

Non-Relative Value Unit-Generating Activities Represent One-Fifth of Academic Neuroradiologist Productivity.

PubMed

Wintermark, M; Zeineh, M; Zaharchuk, G; Srivastava, A; Fischbein, N

2016-07-01

A neuroradiologist's activity includes many tasks beyond interpreting relative value unit-generating imaging studies. Our aim was to test a simple method to record and quantify the non-relative value unit-generating clinical activity represented by consults and clinical conferences, including tumor boards. Four full-time neuroradiologists, working an average of 50% clinical and 50% academic activity, systematically recorded all the non-relative value unit-generating consults and conferences in which they were involved during 3 months by using a simple, Web-based, computer-based application accessible from smartphones, tablets, or computers. The number and type of imaging studies they interpreted during the same period and the associated relative value units were extracted from our billing system. During 3 months, the 4 neuroradiologists working an average of 50% clinical activity interpreted 4241 relative value unit-generating imaging studies, representing 8152 work relative value units. During the same period, they recorded 792 non-relative value unit-generating study reviews as part of consults and conferences (not including reading room consults), representing 19% of the interpreted relative value unit-generating imaging studies. We propose a simple Web-based smartphone app to record and quantify non-relative value unit-generating activities including consults, clinical conferences, and tumor boards. The quantification of non-relative value unit-generating activities is paramount in this time of a paradigm shift from volume to value. It also represents an important tool for determining staffing levels, which cannot be performed on the basis of relative value unit only, considering the importance of time spent by radiologists on non-relative value unit-generating activities. It may also influence payment models from medical centers to radiology departments or practices. © 2016 by American Journal of Neuroradiology.

Adaptation of Control Center Software to Commerical Real-Time Display Applications

NASA Technical Reports Server (NTRS)

Collier, Mark D.

1994-01-01

NASA-Marshall Space Flight Center (MSFC) is currently developing an enhanced Huntsville Operation Support Center (HOSC) system designed to support multiple spacecraft missions. The Enhanced HOSC is based upon a distributed computing architecture using graphic workstation hardware and industry standard software including POSIX, X Windows, Motif, TCP/IP, and ANSI C. Southwest Research Institute (SwRI) is currently developing a prototype of the Display Services application for this system. Display Services provides the capability to generate and operate real-time data-driven graphic displays. This prototype is a highly functional application designed to allow system end users to easily generate complex data-driven displays. The prototype is easy to use, flexible, highly functional, and portable. Although this prototype is being developed for NASA-MSFC, the general-purpose real-time display capability can be reused in similar mission and process control environments. This includes any environment depending heavily upon real-time data acquisition and display. Reuse of the prototype will be a straight-forward transition because the prototype is portable, is designed to add new display types easily, has a user interface which is separated from the application code, and is very independent of the specifics of NASA-MSFC's system. Reuse of this prototype in other environments is a excellent alternative to creation of a new custom application, or for environments with a large number of users, to purchasing a COTS package.

Evaluation of performance of silicon photomultipliers in lidar applications

NASA Astrophysics Data System (ADS)

Vinogradov, Sergey L.

2017-05-01

Silicon Photomultipliers (SiPMs) are a well-recognized new generation of photon number resolving avalanche photodetectors. Many advantages - a high gain with an ultra-low excess noise of multiplication, multi-pixel architecture, relatively low operating voltage - make SiPMs very competitive in a growing number of applications. Challenging demands of LIDAR applications for a receiver having high sensitivity starting from single photons, superior time-offlight resolution, robustness including surviving at bright light flashes, solid-state compactness and more, are expected to be feasible for the SiPMs. Despite some known drawbacks, namely crosstalk, afterpulsing, dark noise, limited dynamic range, SiPMs are already considered as promising substitutes for conventional APDs and PMTs in LIDAR applications. However, these initial considerations are based on a rather simplified representation of the SiPM as a generic LIDAR receiver described by generic expressions. This study is focused on a comprehensive evaluation of a SiPM potential considering essential features of this new technology, which could affect applicability and performance of SiPMs as LIDAR receivers. Namely, an excess noise due to correlated processes of crosstalk and afterpulsing, are included into account utilizing the well-established framework of analytical probabilistic models. The analysis of SiPM performance in terms of a photon number and time resolution clarifies their competitiveness over conventional APD and PMT and anticipates the development of next SiPM generations.

Clinical genomics information management software linking cancer genome sequence and clinical decisions.

PubMed

Watt, Stuart; Jiao, Wei; Brown, Andrew M K; Petrocelli, Teresa; Tran, Ben; Zhang, Tong; McPherson, John D; Kamel-Reid, Suzanne; Bedard, Philippe L; Onetto, Nicole; Hudson, Thomas J; Dancey, Janet; Siu, Lillian L; Stein, Lincoln; Ferretti, Vincent

2013-09-01

Using sequencing information to guide clinical decision-making requires coordination of a diverse set of people and activities. In clinical genomics, the process typically includes sample acquisition, template preparation, genome data generation, analysis to identify and confirm variant alleles, interpretation of clinical significance, and reporting to clinicians. We describe a software application developed within a clinical genomics study, to support this entire process. The software application tracks patients, samples, genomic results, decisions and reports across the cohort, monitors progress and sends reminders, and works alongside an electronic data capture system for the trial's clinical and genomic data. It incorporates systems to read, store, analyze and consolidate sequencing results from multiple technologies, and provides a curated knowledge base of tumor mutation frequency (from the COSMIC database) annotated with clinical significance and drug sensitivity to generate reports for clinicians. By supporting the entire process, the application provides deep support for clinical decision making, enabling the generation of relevant guidance in reports for verification by an expert panel prior to forwarding to the treating physician. Copyright © 2013 Elsevier Inc. All rights reserved.

Development of a Next Generation Air Quality Modeling System

EPA Science Inventory

In the presentation we will describe our modifications to MPAS to improve its suitability for retrospective air quality applications and show evaluations of global and regional meterological simulations. Our modifications include addition of physics schemes that we developed for...

Engineering industrial yeast for renewable advanced biofuels applications

USDA-ARS?s Scientific Manuscript database

The industrial yeast Saccharomyces cerevisiae is a candidate for the next-generation biocatalyst development due to its unique genomic background and robust performance in fermentation-based production. In order to meet challenges of renewable and sustainable advanced biofuels conversion including ...

An Isotope-Powered Thermal Storage unit for space applications

NASA Technical Reports Server (NTRS)

Lisano, Michael E.; Rose, M. F.

1991-01-01

An Isotope-Powered Thermal Storage Unit (ITSU), that would store and utilize heat energy in a 'pulsed' fashion in space operations, is described. Properties of various radioisotopes are considered in conjunction with characteristics of thermal energy storage materials, to evaluate possible implementation of such a device. The utility of the unit is discussed in light of various space applications, including rocket propulsion, power generation, and spacecraft thermal management.

A study of the applicability/compatibility of inertial energy storage systems to future space missions

NASA Technical Reports Server (NTRS)

Weldon, W. F.

1980-01-01

The applicability/compatibility of inertial energy storage systems like the homopolar generator (HPG) and the compensated pulsed alternator (CPA) to future space missions is explored. Areas of CPA and HPG design requiring development for space applications are identified. The manner in which acceptance parameters of the CPA and HPG scale with operating parameters of the machines are explored and the types of electrical loads which are compatible with the CPA and HPG are examined. Potential applications including the magnetoplasmadynamic (MPD) thruster, pulsed data transmission, laser ranging, welding and electromagnetic space launch are discussed.

Electric potential and electric field imaging

NASA Astrophysics Data System (ADS)

Generazio, E. R.

2017-02-01

The technology and methods for remote quantitative imaging of electrostatic potentials and electrostatic fields in and around objects and in free space is presented. Electric field imaging (EFI) technology may be applied to characterize intrinsic or existing electric potentials and electric fields, or an externally generated electrostatic field made be used for "illuminating" volumes to be inspected with EFI. The baseline sensor technology (e-Sensor) and its construction, optional electric field generation (quasi-static generator), and current e-Sensor enhancements (ephemeral e-Sensor) are discussed. Demonstrations for structural, electronic, human, and memory applications are shown. This new EFI capability is demonstrated to reveal characterization of electric charge distribution creating a new field of study embracing areas of interest including electrostatic discharge (ESD) mitigation, crime scene forensics, design and materials selection for advanced sensors, dielectric morphology of structures, tether integrity, organic molecular memory, and medical diagnostic and treatment efficacy applications such as cardiac polarization wave propagation and electromyography imaging.

Nanoparticles as multimodal photon transducers of ionizing radiation

NASA Astrophysics Data System (ADS)

Pratt, Edwin C.; Shaffer, Travis M.; Zhang, Qize; Drain, Charles Michael; Grimm, Jan

2018-05-01

In biomedical imaging, nanoparticles combined with radionuclides that generate Cerenkov luminescence are used in diagnostic imaging, photon-induced therapies and as activatable probes. In these applications, the nanoparticle is often viewed as a carrier inert to ionizing radiation from the radionuclide. However, certain phenomena such as enhanced nanoparticle luminescence and generation of reactive oxygen species cannot be completely explained by Cerenkov luminescence interactions with nanoparticles. Herein, we report methods to examine the mechanisms of nanoparticle excitation by radionuclides, including interactions with Cerenkov luminescence, β particles and γ radiation. We demonstrate that β-scintillation contributes appreciably to excitation and reactivity in certain nanoparticle systems, and that excitation by radionuclides of nanoparticles composed of large atomic number atoms generates X-rays, enabling multiplexed imaging through single photon emission computed tomography. These findings demonstrate practical optical imaging and therapy using radionuclides with emission energies below the Cerenkov threshold, thereby expanding the list of applicable radionuclides.

Light, sound, chemistry… action: state of the art optical methods for animal imaging.

PubMed

Ripoll, Jorge; Ntziachristos, Vasilis

2011-01-01

During recent years, macroscopic optical methods have been promoted from backstage to main actors in biological imaging. Many possible forms of energy conservation have been explored that involve light, including fluorescence emission, sound generated through absorption and bioluminescence, that is light generated through a chemical reaction. These physicochemical approaches for contrast generation have resulted in optical imaging methods that come with potent performance characteristics over simple epi-illumination optical imaging approaches of the past, and can play a central role in imaging applications in vivo as it pertains to modern biological and drug discovery, pre-clinical imaging and clinical applications. This review focuses on state of the art optical and opto-acoustic (photo-acoustic) imaging methods and discusses key performance characteristics that convert optical imaging from a qualitative modality to a powerful high-resolution and quantitative volumetric interrogation tool for operation through several millimeters of tissue depth.: © 2011 Elsevier Ltd . All rights reserved.

Genome Sequencing and Assembly by Long Reads in Plants

PubMed Central

Li, Changsheng; Lin, Feng; An, Dong; Huang, Ruidong

2017-01-01

Plant genomes generated by Sanger and Next Generation Sequencing (NGS) have provided insight into species diversity and evolution. However, Sanger sequencing is limited in its applications due to high cost, labor intensity, and low throughput, while NGS reads are too short to resolve abundant repeats and polyploidy, leading to incomplete or ambiguous assemblies. The advent and improvement of long-read sequencing by Third Generation Sequencing (TGS) methods such as PacBio and Nanopore have shown promise in producing high-quality assemblies for complex genomes. Here, we review the development of sequencing, introducing the application as well as considerations of experimental design in TGS of plant genomes. We also introduce recent revolutionary scaffolding technologies including BioNano, Hi-C, and 10× Genomics. We expect that the informative guidance for genome sequencing and assembly by long reads will benefit the initiation of scientists’ projects. PMID:29283420

Holographic free-electron light source

PubMed Central

Li, Guanhai; Clarke, Brendan P.; So, Jin-Kyu; MacDonald, Kevin F.; Zheludev, Nikolay I.

2016-01-01

Recent advances in the physics and technology of light generation via free-electron proximity and impact interactions with nanostructures (gratings, photonic crystals, nano-undulators, metamaterials and antenna arrays) have enabled the development of nanoscale-resolution techniques for such applications as mapping plasmons, studying nanoparticle structural transformations and characterizing luminescent materials (including time-resolved measurements). Here, we introduce a universal approach allowing generation of light with prescribed wavelength, direction, divergence and topological charge via point-excitation of holographic plasmonic metasurfaces. It is illustrated using medium-energy free-electron injection to generate highly-directional visible to near-infrared light beams, at selected wavelengths in prescribed azimuthal and polar directions, with brightness two orders of magnitude higher than that from an unstructured surface, and vortex beams with topological charge up to ten. Such emitters, with micron-scale dimensions and the freedom to fully control radiation parameters, offer novel applications in nano-spectroscopy, nano-chemistry and sensing. PMID:27910853

Historical Perspective, Development and Applications of Next-Generation Sequencing in Plant Virology

PubMed Central

Barba, Marina; Czosnek, Henryk; Hadidi, Ahmed

2014-01-01

Next-generation high throughput sequencing technologies became available at the onset of the 21st century. They provide a highly efficient, rapid, and low cost DNA sequencing platform beyond the reach of the standard and traditional DNA sequencing technologies developed in the late 1970s. They are continually improved to become faster, more efficient and cheaper. They have been used in many fields of biology since 2004. In 2009, next-generation sequencing (NGS) technologies began to be applied to several areas of plant virology including virus/viroid genome sequencing, discovery and detection, ecology and epidemiology, replication and transcription. Identification and characterization of known and unknown viruses and/or viroids in infected plants are currently among the most successful applications of these technologies. It is expected that NGS will play very significant roles in many research and non-research areas of plant virology. PMID:24399207

New materials graphyne, graphdiyne, graphone, and graphane: review of properties, synthesis, and application in nanotechnology.

PubMed

Peng, Qing; Dearden, Albert K; Crean, Jared; Han, Liang; Liu, Sheng; Wen, Xiaodong; De, Suvranu

2014-01-01

Plenty of new two-dimensional materials including graphyne, graphdiyne, graphone, and graphane have been proposed and unveiled after the discovery of the "wonder material" graphene. Graphyne and graphdiyne are two-dimensional carbon allotropes of graphene with honeycomb structures. Graphone and graphane are hydrogenated derivatives of graphene. The advanced and unique properties of these new materials make them highly promising for applications in next generation nanoelectronics. Here, we briefly review their properties, including structural, mechanical, physical, and chemical properties, as well as their synthesis and applications in nanotechnology. Graphyne is better than graphene in directional electronic properties and charge carriers. With a band gap and magnetism, graphone and graphane show important applications in nanoelectronics and spintronics. Because these materials are close to graphene and will play important roles in carbon-based electronic devices, they deserve further, careful, and thorough studies for nanotechnology applications.

New materials graphyne, graphdiyne, graphone, and graphane: review of properties, synthesis, and application in nanotechnology

PubMed Central

Peng, Qing; Dearden, Albert K; Crean, Jared; Han, Liang; Liu, Sheng; Wen, Xiaodong; De, Suvranu

2014-01-01

Plenty of new two-dimensional materials including graphyne, graphdiyne, graphone, and graphane have been proposed and unveiled after the discovery of the “wonder material” graphene. Graphyne and graphdiyne are two-dimensional carbon allotropes of graphene with honeycomb structures. Graphone and graphane are hydrogenated derivatives of graphene. The advanced and unique properties of these new materials make them highly promising for applications in next generation nanoelectronics. Here, we briefly review their properties, including structural, mechanical, physical, and chemical properties, as well as their synthesis and applications in nanotechnology. Graphyne is better than graphene in directional electronic properties and charge carriers. With a band gap and magnetism, graphone and graphane show important applications in nanoelectronics and spintronics. Because these materials are close to graphene and will play important roles in carbon-based electronic devices, they deserve further, careful, and thorough studies for nanotechnology applications. PMID:24808721

76 FR 30384 - Notice of Intent To Prepare a Draft Environmental Impact Statement for a Proposed Habitat...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-25

... includes the operation of 355 existing wind turbine generators during the first three phases of the project... of up to 448 wind turbines. The project would also include all associated collector lines, access... areas and concrete batch plants, if applicable. Up to five different models of wind turbines may be in...

Generation of the Dimensional Embryology Application (App) for Visualization of Early Chick and Frog Embryonic Development

ERIC Educational Resources Information Center

Webb, Rebecca L.; Bilitski, James; Zerbee, Alyssa; Symans, Alexandra; Chop, Alexandra; Seitz, Brianne; Tran, Cindy

2015-01-01

The study of embryonic development of multiple organisms, including model organisms such as frogs and chicks, is included in many undergraduate biology programs, as well as in a variety of graduate programs. As our knowledge of biological systems increases and the amount of material to be taught expands, the time spent instructing students about…

Thirteenth Workshop for Computational Fluid Dynamic Applications in Rocket Propulsion and Launch Vehicle Technology. Volume 2

NASA Technical Reports Server (NTRS)

Williams, R. W. (Compiler)

1996-01-01

This conference publication includes various abstracts and presentations given at the 13th Workshop for Computational Fluid Dynamic Applications in Rocket Propulsion and Launch Vehicle Technology held at the George C. Marshall Space Flight Center April 25-27 1995. The purpose of the workshop was to discuss experimental and computational fluid dynamic activities in rocket propulsion and launch vehicles. The workshop was an open meeting for government, industry, and academia. A broad number of topics were discussed including computational fluid dynamic methodology, liquid and solid rocket propulsion, turbomachinery, combustion, heat transfer, and grid generation.

Integrated geometry and grid generation system for complex configurations

NASA Technical Reports Server (NTRS)

Akdag, Vedat; Wulf, Armin

1992-01-01

A grid generation system was developed that enables grid generation for complex configurations. The system called ICEM/CFD is described and its role in computational fluid dynamics (CFD) applications is presented. The capabilities of the system include full computer aided design (CAD), grid generation on the actual CAD geometry definition using robust surface projection algorithms, interfacing easily with known CAD packages through common file formats for geometry transfer, grid quality evaluation of the volume grid, coupling boundary condition set-up for block faces with grid topology generation, multi-block grid generation with or without point continuity and block to block interface requirement, and generating grid files directly compatible with known flow solvers. The interactive and integrated approach to the problem of computational grid generation not only substantially reduces manpower time but also increases the flexibility of later grid modifications and enhancements which is required in an environment where CFD is integrated into a product design cycle.

A System for Cost and Reimbursement Control in Hospitals

PubMed Central

Fetter, Robert B.; Thompson, John D.; Mills, Ronald E.

1976-01-01

This paper approaches the design of a regional or statewide hospital rate-setting system as the underpinning of a larger system which permits a regulatory agency to satisfy the requirements of various public laws now on the books or in process. It aims to generate valid interinstitutional monitoring on the three parameters of cost, utilization, and quality review. Such an approach requires the extension of the usual departmental cost and budgeting system to include consideration of the mix of patients treated and the utilization of various resources, including patient days, in the treatment of these patients. A sampling framework for the application of process-based quality studies and the generation of selected performance measurements is also included. PMID:941461

Application of mid-infrared pulses for quasi-phase-matching of high-order harmonics in silver plasma.

PubMed

Ganeev, Rashid A; Husakou, Anton; Suzuki, Masayuki; Kuroda, Hiroto

2016-02-22

We demonstrate the quasi-phase-matching of a group of harmonics generated in Ag multi-jet plasma using tunable pulses in the region of 1160 - 1540 nm and their second harmonic emission. The numerical treatment of this effect includes microscopic description of the harmonic generation, propagation of the pump pulse, and the propagation of the generated harmonics. We obtained more than 30-fold growth of harmonics at the conditions of quasi-phase-matching in the region of 35 nm using eight-jet plasma compared with the case of imperforated plasma.

Realistic generation of natural phenomena based on video synthesis

NASA Astrophysics Data System (ADS)

Wang, Changbo; Quan, Hongyan; Li, Chenhui; Xiao, Zhao; Chen, Xiao; Li, Peng; Shen, Liuwei

2009-10-01

Research on the generation of natural phenomena has many applications in special effects of movie, battlefield simulation and virtual reality, etc. Based on video synthesis technique, a new approach is proposed for the synthesis of natural phenomena, including flowing water and fire flame. From the fire and flow video, the seamless video of arbitrary length is generated. Then, the interaction between wind and fire flame is achieved through the skeleton of flame. Later, the flow is also synthesized by extending the video textures using an edge resample method. Finally, we can integrate the synthesized natural phenomena into a virtual scene.

Feasibility and availability of ⁶⁸Ga-labelled peptides.

PubMed

Decristoforo, Clemens; Pickett, Roger D; Verbruggen, Alfons

2012-02-01

(68)Ga has attracted tremendous interest as a radionuclide for PET based on its suitable half-life of 68 min, high positron emission yield and ready availability from (68)Ge/(68)Ga generators, making it independent of cyclotron production. (68)Ga-labelled DOTA-conjugated somatostatin analogues, including DOTA-TOC, DOTA-TATE and DOTA-NOC, have driven the development of technologies to provide such radiopharmaceuticals for clinical applications mainly in the diagnosis of somatostatin receptor-expressing tumours. We summarize the issues determining the feasibility and availability of (68)Ga-labelled peptides, including generator technology, (68)Ga generator eluate postprocessing methods, radiolabelling, automation and peptide developments, and also quality assurance and regulatory aspects. (68)Ge/(68)Ga generators based on SnO(2), TiO(2) or organic matrices are today routinely supplied to nuclear medicine departments, and a variety of automated systems for postprocessing and radiolabelling have been developed. New developments include improved chelators for (68)Ga that could open new ways to utilize this technology. Challenges and limitations in the on-site preparation and use of (68)Ga-labelled peptides outside the marketing authorization track are also discussed.

Biodegradable Materials for Bone Repair and Tissue Engineering Applications

PubMed Central

Sheikh, Zeeshan; Najeeb, Shariq; Khurshid, Zohaib; Verma, Vivek; Rashid, Haroon; Glogauer, Michael

2015-01-01

This review discusses and summarizes the recent developments and advances in the use of biodegradable materials for bone repair purposes. The choice between using degradable and non-degradable devices for orthopedic and maxillofacial applications must be carefully weighed. Traditional biodegradable devices for osteosynthesis have been successful in low or mild load bearing applications. However, continuing research and recent developments in the field of material science has resulted in development of biomaterials with improved strength and mechanical properties. For this purpose, biodegradable materials, including polymers, ceramics and magnesium alloys have attracted much attention for osteologic repair and applications. The next generation of biodegradable materials would benefit from recent knowledge gained regarding cell material interactions, with better control of interfacing between the material and the surrounding bone tissue. The next generations of biodegradable materials for bone repair and regeneration applications require better control of interfacing between the material and the surrounding bone tissue. Also, the mechanical properties and degradation/resorption profiles of these materials require further improvement to broaden their use and achieve better clinical results. PMID:28793533

Generation of Long-time Complex Signals for Testing the Instruments for Detection of Voltage Quality Disturbances

NASA Astrophysics Data System (ADS)

Živanović, Dragan; Simić, Milan; Kokolanski, Zivko; Denić, Dragan; Dimcev, Vladimir

2018-04-01

Software supported procedure for generation of long-time complex test sentences, suitable for testing the instruments for detection of standard voltage quality (VQ) disturbances is presented in this paper. This solution for test signal generation includes significant improvements of computer-based signal generator presented and described in the previously published paper [1]. The generator is based on virtual instrumentation software for defining the basic signal parameters, data acquisition card NI 6343, and power amplifier for amplification of output voltage level to the nominal RMS voltage value of 230 V. Definition of basic signal parameters in LabVIEW application software is supported using Script files, which allows simple repetition of specific test signals and combination of more different test sequences in the complex composite test waveform. The basic advantage of this generator compared to the similar solutions for signal generation is the possibility for long-time test sequence generation according to predefined complex test scenarios, including various combinations of VQ disturbances defined in accordance with the European standard EN50160. Experimental verification of the presented signal generator capability is performed by testing the commercial power quality analyzer Fluke 435 Series II. In this paper are shown some characteristic complex test signals with various disturbances and logged data obtained from the tested power quality analyzer.

Data catalog series for space science and applications flight missions. Volume 4B: Descriptions of data sets from meteorological and terrestrial applications spacecraft and investigations

NASA Technical Reports Server (NTRS)

Ng, Carolyn; Stonesifer, G. Richard

1989-01-01

The main purpose of the data catalog series is to provide descriptive references to data generated by space science flight missions. The data sets described include all of the actual holdings of the Space Science Data Center (NSSDC), all data sets for which direct contact information is available, and some data collections held and serviced by foreign investigators, NASA and other U.S. government agencies. This volume contains narrative descriptions of data sets from meteorological and terrestrial applications spacecraft and investigations. The following spacecraft series are included: Mariner, Pioneer, Pioneer Venus, Venera, Viking, Voyager, and Helios. Separate indexes to the planetary and interplanetary missions are also provided.

Solar energy for process heat: Design/cost studies of four industrial retrofit applications

NASA Technical Reports Server (NTRS)

French, R. L.; Bartera, R. E.

1978-01-01

Five specific California plants with potentially attractive solar applications were identified in a process heat survey. These five plants were visited, process requirements evaluated, and conceptual solar system designs were generated. Four DOE (ERDA) sponsored solar energy system demonstration projects were also reviewed and compared to the design/cost cases included in this report. In four of the five cases investigated, retrofit installations providing significant amounts of thermal energy were found to be feasible. The fifth was rejected because of the condition of the building involved, but the process (soap making) appears to be an attractive potential solar application. Costs, however, tend to be high. Several potential areas for cost reduction were identified including larger collector modules and higher duty cycles.

Toward accurate and valid estimates of greenhouse gas reductions from bikeway projects.

DOT National Transportation Integrated Search

2016-07-31

We sought to accurately and validly model emissions generating and activities, including changes in traveler behavior and thus GHG : emissions in the wake of bikeway projects. We wanted the results to be applicable to practice and policy in Californi...

METHODS FOR THE SPIRAL SALMONELLA MUTAGENICITY ASSAY INCLUDING SPECIALIZED APPLICATIONS

EPA Science Inventory

ABSTRACT

An automated approach to bacterial mutagenicity testing--the spiral Salmonella assay--was developed to simplify testing and to reduce the labor and materials required to generate dose-responsive mutagenicity information. This document provides the reader with an ...

Geography and glocal scale - generational conversion/Geografia i skala glokalna - przemiana generacyjna

NASA Astrophysics Data System (ADS)

Pirveli, Marika; Lewczuk, Barbara

2013-12-01

The proposed text presents a conceptual change in the scope of some of the key concepts in the light of the two dictionaries (Britannica and Human Geography Dictionary) and Anglo-Saxon publications about the future of geography. Then, it combines the concept of references to the ongoing interdisciplinary studies included in the structure of the University of the Second and Third Generation. Applications built this way are of two types: (1) referring to a fundamental change in the process within the human perception of the environment for generations X and Y, and (2) referring to the process of glocalization, glocal scale and premises of the University of the Third Generation (3GU)

Stirling Convertor Performance Mapping Test Results for Future Radioisotope Power Systems

NASA Astrophysics Data System (ADS)

Qiu, Songgang; Peterson, Allen A.; Faultersack, Franklyn D.; Redinger, Darin L.; Augenblick, John E.

2004-02-01

Long-life radioisotope-fueled generators based on free-piston Stirling convertors are an energy-conversion solution for future space applications. The high efficiency of Stirling machines makes them more attractive than the thermoelectric generators currently used in space. Stirling Technology Company (STC) has been performance-testing its Stirling generators to provide data for potential system integration contractors. This paper describes the most recent test results from the STC RemoteGen™ 55 W-class Stirling generators (RG-55). Comparisons are made between the new data and previous Stirling thermodynamic simulation models. Performance-mapping tests are presented including variations in: internal charge pressure, cold end temperature, hot end temperature, alternator temperature, input power, and variation of control voltage.

Application of Neural Networks to Predict UH-60L Electrical Generator Condition using (IMD-HUMS) Data

DTIC Science & Technology

2006-12-01

Data transfer unit ( DTU ) • Remote data concentrator (RDC) • Main processor unit (MPU) • 2 junction boxes (JB1/JB2) • 20 drive train and...NETWORKS TO PREDICT UH-60L ELECTRICAL GENERATOR CONDITION USING (IMD-HUMS) DATA by Evangelos Tourvalis December 2006 Thesis Advisor...including the time for reviewing instruction, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the

Force to Fail Reactions With Monoethanolamine: Application to the Explosive Destruction System

DTIC Science & Technology

2014-02-01

include good solvent properties for agents, miscibility with water, noncorrosivity to stainless steel under typical EDS operating conditions, and low...50%. However, when the HD loading was ≥50%, noticeable amounts of heat were generated and white fumes were observed to form when the reagent was...heat and fumes were generated when the MEA was added to the HD. At loadings ≥ 80%, the neutralent became so viscous it could not be stirred

Procurement of a fully licensed radioisotope thermoelectric generator transportation system

NASA Astrophysics Data System (ADS)

Adkins, Harold E.; Bearden, Thomas E.

The present transportation system for radioisotope thermoelectric generators and heater units is being developed to comply with all applicable U.S. DOT regulations, including a doubly-contained 'bell jar' concept for the required double-containment of plutonium. Modifications in handling equipment and procedures are entailed by this novel packaging design, and will affect high-capacity forklifts, overhead cranes, He-backfilling equipment, etc. Attention is given to the design constraints involved, and to the Federal procurement process.

Some User's Insights Into ADIFOR 2.0D

NASA Technical Reports Server (NTRS)

Giesy, Daniel P.

2002-01-01

Some insights are given which were gained by one user through experience with the use of the ADIFOR 2.0D software for automatic differentiation of Fortran code. These insights are generally in the area of the user interface with the generated derivative code - particularly the actual form of the interface and the use of derivative objects, including "seed" matrices. Some remarks are given as to how to iterate application of ADIFOR in order to generate second derivative code.

Catheterized plasma X-ray source

DOEpatents

Derzon, Mark S.; Robinson, Alex; Galambos, Paul C.

2017-06-20

A radiation generator useful for medical applications, among others, is provided. The radiation generator includes a catheter; a plasma discharge chamber situated within a terminal portion of the catheter, a cathode and an anode positioned within the plasma discharge chamber and separated by a gap, and a high-voltage transmission line extensive through the interior of the catheter and terminating on the cathode and anode so as to deliver, in operation, one or more voltage pulses across the gap.

Development of next generation tempered and ODS reduced activation ferritic/martensitic steels for fusion energy applications

DOE PAGES

Zinkle, S. J.; Boutard, J. L.; Hoelzer, D. T.; ...

2017-06-09

Reduced activation ferritic/martensitic steels are currently the most technologically mature option for the structural material of proposed fusion energy reactors. Advanced next-generation higher performance steels offer the opportunity for improvements in fusion reactor operational lifetime and reliability, superior neutron radiation damage resistance, higher thermodynamic efficiency, and reduced construction costs. The two main strategies for developing improved steels for fusion energy applications are based on (1) an evolutionary pathway using computational thermodynamics modelling and modified thermomechanical treatments (TMT) to produce higher performance reduced activation ferritic/martensitic (RAFM) steels and (2) a higher risk, potentially higher payoff approach based on powder metallurgy techniquesmore » to produce very high strength oxide dispersion strengthened (ODS) steels capable of operation to very high temperatures and with potentially very high resistance to fusion neutron-induced property degradation. The current development status of these next-generation high performance steels is summarized, and research and development challenges for the successful development of these materials are outlined. In conclusion, material properties including temperature-dependent uniaxial yield strengths, tensile elongations, high-temperature thermal creep, Charpy impact ductile to brittle transient temperature (DBTT) and fracture toughness behaviour, and neutron irradiation-induced low-temperature hardening and embrittlement and intermediate-temperature volumetric void swelling (including effects associated with fusion-relevant helium and hydrogen generation) are described for research heats of the new steels.« less

Development of next generation tempered and ODS reduced activation ferritic/martensitic steels for fusion energy applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zinkle, S. J.; Boutard, J. L.; Hoelzer, D. T.

Reduced activation ferritic/martensitic steels are currently the most technologically mature option for the structural material of proposed fusion energy reactors. Advanced next-generation higher performance steels offer the opportunity for improvements in fusion reactor operational lifetime and reliability, superior neutron radiation damage resistance, higher thermodynamic efficiency, and reduced construction costs. The two main strategies for developing improved steels for fusion energy applications are based on (1) an evolutionary pathway using computational thermodynamics modelling and modified thermomechanical treatments (TMT) to produce higher performance reduced activation ferritic/martensitic (RAFM) steels and (2) a higher risk, potentially higher payoff approach based on powder metallurgy techniquesmore » to produce very high strength oxide dispersion strengthened (ODS) steels capable of operation to very high temperatures and with potentially very high resistance to fusion neutron-induced property degradation. The current development status of these next-generation high performance steels is summarized, and research and development challenges for the successful development of these materials are outlined. In conclusion, material properties including temperature-dependent uniaxial yield strengths, tensile elongations, high-temperature thermal creep, Charpy impact ductile to brittle transient temperature (DBTT) and fracture toughness behaviour, and neutron irradiation-induced low-temperature hardening and embrittlement and intermediate-temperature volumetric void swelling (including effects associated with fusion-relevant helium and hydrogen generation) are described for research heats of the new steels.« less

Development of next generation tempered and ODS reduced activation ferritic/martensitic steels for fusion energy applications

NASA Astrophysics Data System (ADS)

Zinkle, S. J.; Boutard, J. L.; Hoelzer, D. T.; Kimura, A.; Lindau, R.; Odette, G. R.; Rieth, M.; Tan, L.; Tanigawa, H.

2017-09-01

Reduced activation ferritic/martensitic steels are currently the most technologically mature option for the structural material of proposed fusion energy reactors. Advanced next-generation higher performance steels offer the opportunity for improvements in fusion reactor operational lifetime and reliability, superior neutron radiation damage resistance, higher thermodynamic efficiency, and reduced construction costs. The two main strategies for developing improved steels for fusion energy applications are based on (1) an evolutionary pathway using computational thermodynamics modelling and modified thermomechanical treatments (TMT) to produce higher performance reduced activation ferritic/martensitic (RAFM) steels and (2) a higher risk, potentially higher payoff approach based on powder metallurgy techniques to produce very high strength oxide dispersion strengthened (ODS) steels capable of operation to very high temperatures and with potentially very high resistance to fusion neutron-induced property degradation. The current development status of these next-generation high performance steels is summarized, and research and development challenges for the successful development of these materials are outlined. Material properties including temperature-dependent uniaxial yield strengths, tensile elongations, high-temperature thermal creep, Charpy impact ductile to brittle transient temperature (DBTT) and fracture toughness behaviour, and neutron irradiation-induced low-temperature hardening and embrittlement and intermediate-temperature volumetric void swelling (including effects associated with fusion-relevant helium and hydrogen generation) are described for research heats of the new steels.

PREPARING FOR EXASCALE: ORNL Leadership Computing Application Requirements and Strategy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joubert, Wayne; Kothe, Douglas B; Nam, Hai Ah

2009-12-01

In 2009 the Oak Ridge Leadership Computing Facility (OLCF), a U.S. Department of Energy (DOE) facility at the Oak Ridge National Laboratory (ORNL) National Center for Computational Sciences (NCCS), elicited petascale computational science requirements from leading computational scientists in the international science community. This effort targeted science teams whose projects received large computer allocation awards on OLCF systems. A clear finding of this process was that in order to reach their science goals over the next several years, multiple projects will require computational resources in excess of an order of magnitude more powerful than those currently available. Additionally, for themore » longer term, next-generation science will require computing platforms of exascale capability in order to reach DOE science objectives over the next decade. It is generally recognized that achieving exascale in the proposed time frame will require disruptive changes in computer hardware and software. Processor hardware will become necessarily heterogeneous and will include accelerator technologies. Software must undergo the concomitant changes needed to extract the available performance from this heterogeneous hardware. This disruption portends to be substantial, not unlike the change to the message passing paradigm in the computational science community over 20 years ago. Since technological disruptions take time to assimilate, we must aggressively embark on this course of change now, to insure that science applications and their underlying programming models are mature and ready when exascale computing arrives. This includes initiation of application readiness efforts to adapt existing codes to heterogeneous architectures, support of relevant software tools, and procurement of next-generation hardware testbeds for porting and testing codes. The 2009 OLCF requirements process identified numerous actions necessary to meet this challenge: (1) Hardware capabilities must be advanced on multiple fronts, including peak flops, node memory capacity, interconnect latency, interconnect bandwidth, and memory bandwidth. (2) Effective parallel programming interfaces must be developed to exploit the power of emerging hardware. (3) Science application teams must now begin to adapt and reformulate application codes to the new hardware and software, typified by hierarchical and disparate layers of compute, memory and concurrency. (4) Algorithm research must be realigned to exploit this hierarchy. (5) When possible, mathematical libraries must be used to encapsulate the required operations in an efficient and useful way. (6) Software tools must be developed to make the new hardware more usable. (7) Science application software must be improved to cope with the increasing complexity of computing systems. (8) Data management efforts must be readied for the larger quantities of data generated by larger, more accurate science models. Requirements elicitation, analysis, validation, and management comprise a difficult and inexact process, particularly in periods of technological change. Nonetheless, the OLCF requirements modeling process is becoming increasingly quantitative and actionable, as the process becomes more developed and mature, and the process this year has identified clear and concrete steps to be taken. This report discloses (1) the fundamental science case driving the need for the next generation of computer hardware, (2) application usage trends that illustrate the science need, (3) application performance characteristics that drive the need for increased hardware capabilities, (4) resource and process requirements that make the development and deployment of science applications on next-generation hardware successful, and (5) summary recommendations for the required next steps within the computer and computational science communities.« less

Probabilistic tsunami hazard analysis: Multiple sources and global applications

USGS Publications Warehouse

Grezio, Anita; Babeyko, Andrey; Baptista, Maria Ana; Behrens, Jörn; Costa, Antonio; Davies, Gareth; Geist, Eric L.; Glimsdal, Sylfest; González, Frank I.; Griffin, Jonathan; Harbitz, Carl B.; LeVeque, Randall J.; Lorito, Stefano; Løvholt, Finn; Omira, Rachid; Mueller, Christof; Paris, Raphaël; Parsons, Thomas E.; Polet, Jascha; Power, William; Selva, Jacopo; Sørensen, Mathilde B.; Thio, Hong Kie

2017-01-01

Applying probabilistic methods to infrequent but devastating natural events is intrinsically challenging. For tsunami analyses, a suite of geophysical assessments should be in principle evaluated because of the different causes generating tsunamis (earthquakes, landslides, volcanic activity, meteorological events, and asteroid impacts) with varying mean recurrence rates. Probabilistic Tsunami Hazard Analyses (PTHAs) are conducted in different areas of the world at global, regional, and local scales with the aim of understanding tsunami hazard to inform tsunami risk reduction activities. PTHAs enhance knowledge of the potential tsunamigenic threat by estimating the probability of exceeding specific levels of tsunami intensity metrics (e.g., run-up or maximum inundation heights) within a certain period of time (exposure time) at given locations (target sites); these estimates can be summarized in hazard maps or hazard curves. This discussion presents a broad overview of PTHA, including (i) sources and mechanisms of tsunami generation, emphasizing the variety and complexity of the tsunami sources and their generation mechanisms, (ii) developments in modeling the propagation and impact of tsunami waves, and (iii) statistical procedures for tsunami hazard estimates that include the associated epistemic and aleatoric uncertainties. Key elements in understanding the potential tsunami hazard are discussed, in light of the rapid development of PTHA methods during the last decade and the globally distributed applications, including the importance of considering multiple sources, their relative intensities, probabilities of occurrence, and uncertainties in an integrated and consistent probabilistic framework.

Probabilistic Tsunami Hazard Analysis: Multiple Sources and Global Applications

NASA Astrophysics Data System (ADS)

Grezio, Anita; Babeyko, Andrey; Baptista, Maria Ana; Behrens, Jörn; Costa, Antonio; Davies, Gareth; Geist, Eric L.; Glimsdal, Sylfest; González, Frank I.; Griffin, Jonathan; Harbitz, Carl B.; LeVeque, Randall J.; Lorito, Stefano; Løvholt, Finn; Omira, Rachid; Mueller, Christof; Paris, Raphaël.; Parsons, Tom; Polet, Jascha; Power, William; Selva, Jacopo; Sørensen, Mathilde B.; Thio, Hong Kie

2017-12-01

Applying probabilistic methods to infrequent but devastating natural events is intrinsically challenging. For tsunami analyses, a suite of geophysical assessments should be in principle evaluated because of the different causes generating tsunamis (earthquakes, landslides, volcanic activity, meteorological events, and asteroid impacts) with varying mean recurrence rates. Probabilistic Tsunami Hazard Analyses (PTHAs) are conducted in different areas of the world at global, regional, and local scales with the aim of understanding tsunami hazard to inform tsunami risk reduction activities. PTHAs enhance knowledge of the potential tsunamigenic threat by estimating the probability of exceeding specific levels of tsunami intensity metrics (e.g., run-up or maximum inundation heights) within a certain period of time (exposure time) at given locations (target sites); these estimates can be summarized in hazard maps or hazard curves. This discussion presents a broad overview of PTHA, including (i) sources and mechanisms of tsunami generation, emphasizing the variety and complexity of the tsunami sources and their generation mechanisms, (ii) developments in modeling the propagation and impact of tsunami waves, and (iii) statistical procedures for tsunami hazard estimates that include the associated epistemic and aleatoric uncertainties. Key elements in understanding the potential tsunami hazard are discussed, in light of the rapid development of PTHA methods during the last decade and the globally distributed applications, including the importance of considering multiple sources, their relative intensities, probabilities of occurrence, and uncertainties in an integrated and consistent probabilistic framework.

MALDI Imaging Mass Spectrometry (MALDI-IMS)—Application of Spatial Proteomics for Ovarian Cancer Classification and Diagnosis

PubMed Central

Gustafsson, Johan O. R.; Oehler, Martin K.; Ruszkiewicz, Andrew; McColl, Shaun R.; Hoffmann, Peter

2011-01-01

MALDI imaging mass spectrometry (MALDI-IMS) allows acquisition of mass data for metabolites, lipids, peptides and proteins directly from tissue sections. IMS is typically performed either as a multiple spot profiling experiment to generate tissue specific mass profiles, or a high resolution imaging experiment where relative spatial abundance for potentially hundreds of analytes across virtually any tissue section can be measured. Crucially, imaging can be achieved without prior knowledge of tissue composition and without the use of antibodies. In effect MALDI-IMS allows generation of molecular data which complement and expand upon the information provided by histology including immuno-histochemistry, making its application valuable to both cancer biomarker research and diagnostics. The current state of MALDI-IMS, key biological applications to ovarian cancer research and practical considerations for analysis of peptides and proteins on ovarian tissue are presented in this review. PMID:21340013

MALDI Imaging Mass Spectrometry (MALDI-IMS)-application of spatial proteomics for ovarian cancer classification and diagnosis.

PubMed

Gustafsson, Johan O R; Oehler, Martin K; Ruszkiewicz, Andrew; McColl, Shaun R; Hoffmann, Peter

2011-01-21

MALDI imaging mass spectrometry (MALDI-IMS) allows acquisition of mass data for metabolites, lipids, peptides and proteins directly from tissue sections. IMS is typically performed either as a multiple spot profiling experiment to generate tissue specific mass profiles, or a high resolution imaging experiment where relative spatial abundance for potentially hundreds of analytes across virtually any tissue section can be measured. Crucially, imaging can be achieved without prior knowledge of tissue composition and without the use of antibodies. In effect MALDI-IMS allows generation of molecular data which complement and expand upon the information provided by histology including immuno-histochemistry, making its application valuable to both cancer biomarker research and diagnostics. The current state of MALDI-IMS, key biological applications to ovarian cancer research and practical considerations for analysis of peptides and proteins on ovarian tissue are presented in this review.

The past as prologue - A look at historical flight qualifications for space nuclear systems

NASA Technical Reports Server (NTRS)

Bennett, Gary L.

1992-01-01

Currently the U.S. is sponsoring production of radioisotope thermoelectric generators (RTGs) for the Cassini mission to Saturn; the SP-100 space nuclear reactor power system for NASA applications; a thermionic space reactor program for DoD applications as well as early work on nuclear propulsion. In an era of heightened public concern about having successful space ventures it is important that a full understanding be developed of what it means to 'flight qualify' a space nuclear system. As a contribution to the ongoing work this paper reviews several qualification programs, including the general-purpose heat source radioisotope thermoelectric generators (GPHS-RTGs) as developed for the Galileo and Ulysses missions, the SNAP-10A space reactor, the Nuclear Engine for Rocket Vehicle Applications (NERVA), the F-1 chemical engine used on the Saturn-V, and the Space Shuttle Main Engines (SSMEs). Similarities and contrasts are noted.

The past as prologue - A look at historical flight qualifications for space nuclear systems

NASA Astrophysics Data System (ADS)

Bennett, Gary L.

Currently the U.S. is sponsoring production of radioisotope thermoelectric generators (RTGs) for the Cassini mission to Saturn; the SP-100 space nuclear reactor power system for NASA applications; a thermionic space reactor program for DoD applications as well as early work on nuclear propulsion. In an era of heightened public concern about having successful space ventures it is important that a full understanding be developed of what it means to 'flight qualify' a space nuclear system. As a contribution to the ongoing work this paper reviews several qualification programs, including the general-purpose heat source radioisotope thermoelectric generators (GPHS-RTGs) as developed for the Galileo and Ulysses missions, the SNAP-10A space reactor, the Nuclear Engine for Rocket Vehicle Applications (NERVA), the F-1 chemical engine used on the Saturn-V, and the Space Shuttle Main Engines (SSMEs). Similarities and contrasts are noted.

A novel source of MeV positron bunches driven by energetic protons for PAS application

NASA Astrophysics Data System (ADS)

Tan, Zongquan; Xu, Wenzhen; Liu, Yanfen; Xiao, Ran; Kong, Wei; Ye, Bangjiao

2014-11-01

This paper proposes a novel methodology of MeV positrons generation for PAS application. Feasibility of this proposal analyzed by G4Beamline and Transport have shown reasonable success. Using 2 Hz, 1.6 GeV, 100 ns and 1.5 μC/bunch proton bunches for bombarding a graphite target, about 100 ns e+ bunches are generated. Quasi-monochromatic positrons in the range of 1-10 MeV included in these bunches have a flux of >107/s, peak brightness of 1014/s. A magnetic-confinement beamline is utilized to transport the positrons and a "Fast Beam Chopper" is unprecedentedly extended to chop those relativistic bunches. The positron beam can be finally characterized by the energy range of 1-10 MeV and bunch width from one hundred ps up to 1 ns. Such ultrashort bunches can be useful in tomography-type positron annihilation spectroscopy (PAS) as well as other applications.

Solar thermal power systems point-focusing thermal and electric applications projects. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Marriott, A.

1980-01-01

The activities of the Point-Focusing Thermal and Electric Applications (PETEA) project for the fiscal year 1979 are summarized. The main thrust of the PFTEA Project, the small community solar thermal power experiment, was completed. Concept definition studies included a small central receiver approach, a point-focusing distributed receiver system with central power generation, and a point-focusing distributed receiver concept with distributed power generation. The first experiment in the Isolated Application Series was initiated. Planning for the third engineering experiment series, which addresses the industrial market sector, was also initiated. In addition to the experiment-related activities, several contracts to industry were let and studies were conducted to explore the market potential for point-focusing distributed receiver (PFDR) systems. System analysis studies were completed that looked at PFDR technology relative to other small power system technology candidates for the utility market sector.

Developmental history and application of CRISPR in human disease.

PubMed

Liang, Puping; Zhang, Xiya; Chen, Yuxi; Huang, Junjiu

2017-06-01

Genome-editing tools are programmable artificial nucleases, mainly including zinc-finger nucleases, transcription activator-like effector nucleases and clustered regularly interspaced short palindromic repeat (CRISPR). By recognizing and cleaving specific DNA sequences, genome-editing tools make it possible to generate site-specific DNA double-strand breaks (DSBs) in the genome. DSBs will then be repaired by either error-prone nonhomologous end joining or high-fidelity homologous recombination mechanisms. Through these two different mechanisms, endogenous genes can be knocked out or precisely repaired/modified. Rapid developments in genome-editing tools, especially CRISPR, have revolutionized human disease models generation, for example, various zebrafish, mouse, rat, pig, monkey and human cell lines have been constructed. Here, we review the developmental history of CRISPR and its application in studies of human diseases. In addition, we also briefly discussed the therapeutic application of CRISPR in the near future. Copyright © 2017 John Wiley & Sons, Ltd.

Gas Chromatic Mass Spectrometer

NASA Technical Reports Server (NTRS)

Wey, Chowen

1995-01-01

Gas chromatograph/mass spectrometer (GC/MS) used to measure and identify combustion species present in trace concentration. Advanced extractive diagnostic method measures to parts per billion (PPB), as well as differentiates between different types of hydrocarbons. Applicable for petrochemical, waste incinerator, diesel transporation, and electric utility companies in accurately monitoring types of hydrocarbon emissions generated by fuel combustion, in order to meet stricter environmental requirements. Other potential applications include manufacturing processes requiring precise detection of toxic gaseous chemicals, biomedical applications requiring precise identification of accumulative gaseous species, and gas utility operations requiring high-sensitivity leak detection.

GIS -- Is it a money pit or a profit generator?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sutton, R.H.

1997-02-01

Today, new technologies including smart pigs and GPS technology can be used to expedite data collection and improve the accuracy of the GIS applications. Eventually, such applications as pipe information for a taxing district, corrosion testing history, and many other applications can be accommodated in a GIS system. The accompanying figure shows the potential relationship of various technologies in today`s world along with other automated data input sources such as very smart pigs and the Global Positioning System (GPS). The paper discusses implementation barriers, assuring success, and recommendations.

Application Note: Power Grid Modeling With Xyce.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sholander, Peter E.

This application note describes how to model steady-state power flows and transient events in electric power grids with the SPICE-compatible Xyce TM Parallel Electronic Simulator developed at Sandia National Labs. This application notes provides a brief tutorial on the basic devices (branches, bus shunts, transformers and generators) found in power grids. The focus is on the features supported and assumptions made by the Xyce models for power grid elements. It then provides a detailed explanation, including working Xyce netlists, for simulating some simple power grid examples such as the IEEE 14-bus test case.

Applying Monte Carlo Simulation to Launch Vehicle Design and Requirements Analysis

NASA Technical Reports Server (NTRS)

Hanson, J. M.; Beard, B. B.

2010-01-01

This Technical Publication (TP) is meant to address a number of topics related to the application of Monte Carlo simulation to launch vehicle design and requirements analysis. Although the focus is on a launch vehicle application, the methods may be applied to other complex systems as well. The TP is organized so that all the important topics are covered in the main text, and detailed derivations are in the appendices. The TP first introduces Monte Carlo simulation and the major topics to be discussed, including discussion of the input distributions for Monte Carlo runs, testing the simulation, how many runs are necessary for verification of requirements, what to do if results are desired for events that happen only rarely, and postprocessing, including analyzing any failed runs, examples of useful output products, and statistical information for generating desired results from the output data. Topics in the appendices include some tables for requirements verification, derivation of the number of runs required and generation of output probabilistic data with consumer risk included, derivation of launch vehicle models to include possible variations of assembled vehicles, minimization of a consumable to achieve a two-dimensional statistical result, recontact probability during staging, ensuring duplicated Monte Carlo random variations, and importance sampling.

[Skeleton extractions and applications].

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quadros, William Roshan

2010-05-01

This paper focuses on the extraction of skeletons of CAD models and its applications in finite element (FE) mesh generation. The term 'skeleton of a CAD model' can be visualized as analogous to the 'skeleton of a human body'. The skeletal representations covered in this paper include medial axis transform (MAT), Voronoi diagram (VD), chordal axis transform (CAT), mid surface, digital skeletons, and disconnected skeletons. In the literature, the properties of a skeleton have been utilized in developing various algorithms for extracting skeletons. Three main approaches include: (1) the bisection method where the skeleton exists at equidistant from at leastmore » two points on boundary, (2) the grassfire propagation method in which the skeleton exists where the opposing fronts meet, and (3) the duality method where the skeleton is a dual of the object. In the last decade, the author has applied different skeletal representations in all-quad meshing, hex meshing, mid-surface meshing, mesh size function generation, defeaturing, and decomposition. A brief discussion on the related work from other researchers in the area of tri meshing, tet meshing, and anisotropic meshing is also included. This paper concludes by summarizing the strengths and weaknesses of the skeleton-based approaches in solving various geometry-centered problems in FE mesh generation. The skeletons have proved to be a great shape abstraction tool in analyzing the geometric complexity of CAD models as they are symmetric, simpler (reduced dimension), and provide local thickness information. However, skeletons generally require some cleanup, and stability and sensitivity of the skeletons should be controlled during extraction. Also, selecting a suitable application-specific skeleton and a computationally efficient method of extraction is critical.« less

ADAM: An Accident Diagnostic,Analysis and Management System - Applications to Severe Accident Simulation and Management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zavisca, M.J.; Khatib-Rahbar, M.; Esmaili, H.

2002-07-01

The Accident Diagnostic, Analysis and Management (ADAM) computer code has been developed as a tool for on-line applications to accident diagnostics, simulation, management and training. ADAM's severe accident simulation capabilities incorporate a balance of mechanistic, phenomenologically based models with simple parametric approaches for elements including (but not limited to) thermal hydraulics; heat transfer; fuel heatup, meltdown, and relocation; fission product release and transport; combustible gas generation and combustion; and core-concrete interaction. The overall model is defined by a relatively coarse spatial nodalization of the reactor coolant and containment systems and is advanced explicitly in time. The result is to enablemore » much faster than real time (i.e., 100 to 1000 times faster than real time on a personal computer) applications to on-line investigations and/or accident management training. Other features of the simulation module include provision for activation of water injection, including the Engineered Safety Features, as well as other mechanisms for the assessment of accident management and recovery strategies and the evaluation of PSA success criteria. The accident diagnostics module of ADAM uses on-line access to selected plant parameters (as measured by plant sensors) to compute the thermodynamic state of the plant, and to predict various margins to safety (e.g., times to pressure vessel saturation and steam generator dryout). Rule-based logic is employed to classify the measured data as belonging to one of a number of likely scenarios based on symptoms, and a number of 'alarms' are generated to signal the state of the reactor and containment. This paper will address the features and limitations of ADAM with particular focus on accident simulation and management. (authors)« less

Agricultural and hydrological applications of radar

NASA Technical Reports Server (NTRS)

Ulaby, F. T.

1976-01-01

Program objectives, covering a wide range of disciplines and activities in radar remote sensing, include radar systems development and analysis, data processing and display, and data interpretation in geology, geography and oceanography. Research was focused on the evaluation of radar remote sensing applications in hydrology and agriculture based on data acquired with the Microwave Active Spectrometer (MAS) system. The title, author(s) and abstract of each of the 62 technical reports generated under this contract are appended.

Achieving High Performance in Parallel Applications via Kernel-Application Interaction

DTIC Science & Technology

1996-04-01

time systems include airplane autopilot or nuclear power plant control. New complex, parallel soft real-time applica- tions have been generating...to keep as many sheep on the table as possible, and the more powerful the sheep behavior-models and look-ahead, the better the results. General...fact that it provides considerable flexibility when considering the amount of processing power to allocate to a planner. In this experiment we again

Transformation Systems at NASA Ames

NASA Technical Reports Server (NTRS)

Buntine, Wray; Fischer, Bernd; Havelund, Klaus; Lowry, Michael; Pressburger, TOm; Roach, Steve; Robinson, Peter; VanBaalen, Jeffrey

1999-01-01

In this paper, we describe the experiences of the Automated Software Engineering Group at the NASA Ames Research Center in the development and application of three different transformation systems. The systems span the entire technology range, from deductive synthesis, to logic-based transformation, to almost compiler-like source-to-source transformation. These systems also span a range of NASA applications, including solving solar system geometry problems, generating data analysis software, and analyzing multi-threaded Java code.

Comparing microarrays and next-generation sequencing technologies for microbial ecology research.

PubMed

Roh, Seong Woon; Abell, Guy C J; Kim, Kyoung-Ho; Nam, Young-Do; Bae, Jin-Woo

2010-06-01

Recent advances in molecular biology have resulted in the application of DNA microarrays and next-generation sequencing (NGS) technologies to the field of microbial ecology. This review aims to examine the strengths and weaknesses of each of the methodologies, including depth and ease of analysis, throughput and cost-effectiveness. It also intends to highlight the optimal application of each of the individual technologies toward the study of a particular environment and identify potential synergies between the two main technologies, whereby both sample number and coverage can be maximized. We suggest that the efficient use of microarray and NGS technologies will allow researchers to advance the field of microbial ecology, and importantly, improve our understanding of the role of microorganisms in their various environments.

The Nasa-Isro SAR Mission Science Data Products and Processing Workflows

NASA Astrophysics Data System (ADS)

Rosen, P. A.; Agram, P. S.; Lavalle, M.; Cohen, J.; Buckley, S.; Kumar, R.; Misra-Ray, A.; Ramanujam, V.; Agarwal, K. M.

2017-12-01

The NASA-ISRO SAR (NISAR) Mission is currently in the development phase and in the process of specifying its suite of data products and algorithmic workflows, responding to inputs from the NISAR Science and Applications Team. NISAR will provide raw data (Level 0), full-resolution complex imagery (Level 1), and interferometric and polarimetric image products (Level 2) for the entire data set, in both natural radar and geocoded coordinates. NASA and ISRO are coordinating the formats, meta-data layers, and algorithms for these products, for both the NASA-provided L-band radar and the ISRO-provided S-band radar. Higher level products will be also be generated for the purpose of calibration and validation, over large areas of Earth, including tectonic plate boundaries, ice sheets and sea-ice, and areas of ecosystem disturbance and change. This level of comprehensive product generation has been unprecedented for SAR missions in the past, and leads to storage processing challenges for the production system and the archive center. Further, recognizing the potential to support applications that require low latency product generation and delivery, the NISAR team is optimizing the entire end-to-end ground data system for such response, including exploring the advantages of cloud-based processing, algorithmic acceleration using GPUs, and on-demand processing schemes that minimize computational and transport costs, but allow rapid delivery to science and applications users. This paper will review the current products, workflows, and discuss the scientific and operational trade-space of mission capabilities.

General Purpose Data-Driven Online System Health Monitoring with Applications to Space Operations

NASA Technical Reports Server (NTRS)

Iverson, David L.; Spirkovska, Lilly; Schwabacher, Mark

2010-01-01

Modern space transportation and ground support system designs are becoming increasingly sophisticated and complex. Determining the health state of these systems using traditional parameter limit checking, or model-based or rule-based methods is becoming more difficult as the number of sensors and component interactions grows. Data-driven monitoring techniques have been developed to address these issues by analyzing system operations data to automatically characterize normal system behavior. System health can be monitored by comparing real-time operating data with these nominal characterizations, providing detection of anomalous data signatures indicative of system faults, failures, or precursors of significant failures. The Inductive Monitoring System (IMS) is a general purpose, data-driven system health monitoring software tool that has been successfully applied to several aerospace applications and is under evaluation for anomaly detection in vehicle and ground equipment for next generation launch systems. After an introduction to IMS application development, we discuss these NASA online monitoring applications, including the integration of IMS with complementary model-based and rule-based methods. Although the examples presented in this paper are from space operations applications, IMS is a general-purpose health-monitoring tool that is also applicable to power generation and transmission system monitoring.

Application of Generative Autoencoder in De Novo Molecular Design.

PubMed

Blaschke, Thomas; Olivecrona, Marcus; Engkvist, Ola; Bajorath, Jürgen; Chen, Hongming

2018-01-01

A major challenge in computational chemistry is the generation of novel molecular structures with desirable pharmacological and physiochemical properties. In this work, we investigate the potential use of autoencoder, a deep learning methodology, for de novo molecular design. Various generative autoencoders were used to map molecule structures into a continuous latent space and vice versa and their performance as structure generator was assessed. Our results show that the latent space preserves chemical similarity principle and thus can be used for the generation of analogue structures. Furthermore, the latent space created by autoencoders were searched systematically to generate novel compounds with predicted activity against dopamine receptor type 2 and compounds similar to known active compounds not included in the trainings set were identified. © 2018 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Highly Reconfigurable Beamformer Stimulus Generator

NASA Astrophysics Data System (ADS)

Vaviļina, E.; Gaigals, G.

2018-02-01

The present paper proposes a highly reconfigurable beamformer stimulus generator of radar antenna array, which includes three main blocks: settings of antenna array, settings of objects (signal sources) and a beamforming simulator. Following from the configuration of antenna array and object settings, different stimulus can be generated as the input signal for a beamformer. This stimulus generator is developed under a greater concept with two utterly independent paths where one is the stimulus generator and the other is the hardware beamformer. Both paths can be complemented in final and in intermediate steps as well to check and improve system performance. This way the technology development process is promoted by making each of the future hardware steps more substantive. Stimulus generator configuration capabilities and test results are presented proving the application of the stimulus generator for FPGA based beamforming unit development and tuning as an alternative to an actual antenna system.

A Critical Review of Proposition Analysis in Alzheimer's Research and Elsewhere

ERIC Educational Resources Information Center

King, James R.

2012-01-01

Propositional analysis of text, including the generation of proposition density ratios, is examined within the context of Alzheimer's research. A discussion of linguistic modularity raises questions regarding the outcomes of propositional analysis and its applications in Alzheimer's research. (Contains 1 figure.)

77 FR 3754 - Boise Project Board of Control; Notice of Application Accepted for Filing, Soliciting Comments...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-25

... design change that includes two horizontal Francis turbines and a single horizontal generator on a common shaft. The nameplate capacity of the project would increase from 650 kW to 1,100 kW, and the hydraulic...

Numerical grid generation techniques. [conference

NASA Technical Reports Server (NTRS)

1980-01-01

The state of the art in topology and flow geometry is presented. Solution techniques for partial differential equations are reviewed and included developments in coordinate transformations, conformal mapping, and invariant imbeddings. Applications of these techniques in fluid mechanics, flow geometry, boundary value problems, and fluidics are presented.

Photonics

NASA Technical Reports Server (NTRS)

1991-01-01

Optoelectronic materials and devices are examined. Optoelectronic devices, which generate, detect, modulate, or switch electromagnetic radiation are being developed for a variety of space applications. The program includes spatial light modulators, solid state lasers, optoelectronic integrated circuits, nonlinear optical materials and devices, fiber optics, and optical networking photovoltaic technology and optical processing.

Proceedings of the Second International Colloquium on Drops and Bubbles

NASA Technical Reports Server (NTRS)

Lecroissette, D. H. (Editor)

1982-01-01

Applications of bubble and drop technologies are discussed and include: low gravity manufacturing, containerless melts, microballoon fabrication, ink printers, laser fusion targets, generation of organic glass and metal shells, and space processing. The fluid dynamics of bubbles and drops were examined. Thermomigration, capillary flow, and interfacial tension are discussed. Techniques for drop control are presented and include drop size control and drop shape control.

Biotechnology, Industry Study, Spring 2009

DTIC Science & Technology

2009-01-01

roots to zymotechnology ( fermentation ), practiced by the Sumerians and Babylonians as early as 6,000 B.C.3 This core technology expanded to other...applications, including using yeast to make bread, bacteria to derive yogurt , and molds to make cheeses.4 Early biotechnology endeavors included...alcohol or ethanol. This first generation process uses the fermentation of sugars or starches to produce ethanol but is dependent upon corn, a

Guidelines for Genome-Scale Analysis of Biological Rhythms.

PubMed

Hughes, Michael E; Abruzzi, Katherine C; Allada, Ravi; Anafi, Ron; Arpat, Alaaddin Bulak; Asher, Gad; Baldi, Pierre; de Bekker, Charissa; Bell-Pedersen, Deborah; Blau, Justin; Brown, Steve; Ceriani, M Fernanda; Chen, Zheng; Chiu, Joanna C; Cox, Juergen; Crowell, Alexander M; DeBruyne, Jason P; Dijk, Derk-Jan; DiTacchio, Luciano; Doyle, Francis J; Duffield, Giles E; Dunlap, Jay C; Eckel-Mahan, Kristin; Esser, Karyn A; FitzGerald, Garret A; Forger, Daniel B; Francey, Lauren J; Fu, Ying-Hui; Gachon, Frédéric; Gatfield, David; de Goede, Paul; Golden, Susan S; Green, Carla; Harer, John; Harmer, Stacey; Haspel, Jeff; Hastings, Michael H; Herzel, Hanspeter; Herzog, Erik D; Hoffmann, Christy; Hong, Christian; Hughey, Jacob J; Hurley, Jennifer M; de la Iglesia, Horacio O; Johnson, Carl; Kay, Steve A; Koike, Nobuya; Kornacker, Karl; Kramer, Achim; Lamia, Katja; Leise, Tanya; Lewis, Scott A; Li, Jiajia; Li, Xiaodong; Liu, Andrew C; Loros, Jennifer J; Martino, Tami A; Menet, Jerome S; Merrow, Martha; Millar, Andrew J; Mockler, Todd; Naef, Felix; Nagoshi, Emi; Nitabach, Michael N; Olmedo, Maria; Nusinow, Dmitri A; Ptáček, Louis J; Rand, David; Reddy, Akhilesh B; Robles, Maria S; Roenneberg, Till; Rosbash, Michael; Ruben, Marc D; Rund, Samuel S C; Sancar, Aziz; Sassone-Corsi, Paolo; Sehgal, Amita; Sherrill-Mix, Scott; Skene, Debra J; Storch, Kai-Florian; Takahashi, Joseph S; Ueda, Hiroki R; Wang, Han; Weitz, Charles; Westermark, Pål O; Wijnen, Herman; Xu, Ying; Wu, Gang; Yoo, Seung-Hee; Young, Michael; Zhang, Eric Erquan; Zielinski, Tomasz; Hogenesch, John B

2017-10-01

Genome biology approaches have made enormous contributions to our understanding of biological rhythms, particularly in identifying outputs of the clock, including RNAs, proteins, and metabolites, whose abundance oscillates throughout the day. These methods hold significant promise for future discovery, particularly when combined with computational modeling. However, genome-scale experiments are costly and laborious, yielding "big data" that are conceptually and statistically difficult to analyze. There is no obvious consensus regarding design or analysis. Here we discuss the relevant technical considerations to generate reproducible, statistically sound, and broadly useful genome-scale data. Rather than suggest a set of rigid rules, we aim to codify principles by which investigators, reviewers, and readers of the primary literature can evaluate the suitability of different experimental designs for measuring different aspects of biological rhythms. We introduce CircaInSilico, a web-based application for generating synthetic genome biology data to benchmark statistical methods for studying biological rhythms. Finally, we discuss several unmet analytical needs, including applications to clinical medicine, and suggest productive avenues to address them.

Guidelines for Genome-Scale Analysis of Biological Rhythms

PubMed Central

Hughes, Michael E.; Abruzzi, Katherine C.; Allada, Ravi; Anafi, Ron; Arpat, Alaaddin Bulak; Asher, Gad; Baldi, Pierre; de Bekker, Charissa; Bell-Pedersen, Deborah; Blau, Justin; Brown, Steve; Ceriani, M. Fernanda; Chen, Zheng; Chiu, Joanna C.; Cox, Juergen; Crowell, Alexander M.; DeBruyne, Jason P.; Dijk, Derk-Jan; DiTacchio, Luciano; Doyle, Francis J.; Duffield, Giles E.; Dunlap, Jay C.; Eckel-Mahan, Kristin; Esser, Karyn A.; FitzGerald, Garret A.; Forger, Daniel B.; Francey, Lauren J.; Fu, Ying-Hui; Gachon, Frédéric; Gatfield, David; de Goede, Paul; Golden, Susan S.; Green, Carla; Harer, John; Harmer, Stacey; Haspel, Jeff; Hastings, Michael H.; Herzel, Hanspeter; Herzog, Erik D.; Hoffmann, Christy; Hong, Christian; Hughey, Jacob J.; Hurley, Jennifer M.; de la Iglesia, Horacio O.; Johnson, Carl; Kay, Steve A.; Koike, Nobuya; Kornacker, Karl; Kramer, Achim; Lamia, Katja; Leise, Tanya; Lewis, Scott A.; Li, Jiajia; Li, Xiaodong; Liu, Andrew C.; Loros, Jennifer J.; Martino, Tami A.; Menet, Jerome S.; Merrow, Martha; Millar, Andrew J.; Mockler, Todd; Naef, Felix; Nagoshi, Emi; Nitabach, Michael N.; Olmedo, Maria; Nusinow, Dmitri A.; Ptáček, Louis J.; Rand, David; Reddy, Akhilesh B.; Robles, Maria S.; Roenneberg, Till; Rosbash, Michael; Ruben, Marc D.; Rund, Samuel S.C.; Sancar, Aziz; Sassone-Corsi, Paolo; Sehgal, Amita; Sherrill-Mix, Scott; Skene, Debra J.; Storch, Kai-Florian; Takahashi, Joseph S.; Ueda, Hiroki R.; Wang, Han; Weitz, Charles; Westermark, Pål O.; Wijnen, Herman; Xu, Ying; Wu, Gang; Yoo, Seung-Hee; Young, Michael; Zhang, Eric Erquan; Zielinski, Tomasz; Hogenesch, John B.

2017-01-01

Genome biology approaches have made enormous contributions to our understanding of biological rhythms, particularly in identifying outputs of the clock, including RNAs, proteins, and metabolites, whose abundance oscillates throughout the day. These methods hold significant promise for future discovery, particularly when combined with computational modeling. However, genome-scale experiments are costly and laborious, yielding “big data” that are conceptually and statistically difficult to analyze. There is no obvious consensus regarding design or analysis. Here we discuss the relevant technical considerations to generate reproducible, statistically sound, and broadly useful genome-scale data. Rather than suggest a set of rigid rules, we aim to codify principles by which investigators, reviewers, and readers of the primary literature can evaluate the suitability of different experimental designs for measuring different aspects of biological rhythms. We introduce CircaInSilico, a web-based application for generating synthetic genome biology data to benchmark statistical methods for studying biological rhythms. Finally, we discuss several unmet analytical needs, including applications to clinical medicine, and suggest productive avenues to address them. PMID:29098954

Human pluripotent stem cells: Prospects and challenges as a source of cardiomyocytes for in vitro modeling and cell-based cardiac repair.

PubMed

Hartman, Matthew E; Dai, Dao-Fu; Laflamme, Michael A

2016-01-15

Human pluripotent stem cells (PSCs) represent an attractive source of cardiomyocytes with potential applications including disease modeling, drug discovery and safety screening, and novel cell-based cardiac therapies. Insights from embryology have contributed to the development of efficient, reliable methods capable of generating large quantities of human PSC-cardiomyocytes with cardiac purities ranging up to 90%. However, for human PSCs to meet their full potential, the field must identify methods to generate cardiomyocyte populations that are uniform in subtype (e.g. homogeneous ventricular cardiomyocytes) and have more mature structural and functional properties. For in vivo applications, cardiomyocyte production must be highly scalable and clinical grade, and we will need to overcome challenges including graft cell death, immune rejection, arrhythmogenesis, and tumorigenic potential. Here we discuss the types of human PSCs, commonly used methods to guide their differentiation into cardiomyocytes, the phenotype of the resultant cardiomyocytes, and the remaining obstacles to their successful translation. Copyright © 2015 Elsevier B.V. All rights reserved.

Photovoltaic solar array technology required for three wide scale generating systems for terrestrial applications: rooftop, solar farm, and satellite

NASA Technical Reports Server (NTRS)

Berman, P. A.

1972-01-01

Three major options for wide-scale generation of photovoltaic energy for terrestrial use are considered: (1) rooftop array, (2) solar farm, and (3) satellite station. The rooftop array would use solar cell arrays on the roofs of residential or commercial buildings; the solar farm would consist of large ground-based arrays, probably in arid areas with high insolation; and the satellite station would consist of an orbiting solar array, many square kilometers in area. The technology advancement requirements necessary for each option are discussed, including cost reduction of solar cells and arrays, weight reduction, resistance to environmental factors, reliability, and fabrication capability, including the availability of raw materials. The majority of the technology advancement requirements are applicable to all three options, making possible a flexible basic approach regardless of the options that may eventually be chosen. No conclusions are drawn as to which option is most advantageous, since the feasibility of each option depends on the success achieved in the technology advancement requirements specified.

Applications of phase-contrast x-ray imaging to medicine using an x-ray interferometer

NASA Astrophysics Data System (ADS)

Momose, Atsushi; Yoneyama, Akio; Takeda, Tohoru; Itai, Yuji; Tu, Jinhong; Hirano, Keiichi

1999-10-01

We are investigating possible medical applications of phase- contrast X-ray imaging using an X-ray interferometer. This paper introduces the strategy of the research project and the present status. The main subject is to broaden the observation area to enable in vivo observation. For this purpose, large X-ray interferometers were developed, and 2.5 cm X 1.5 cm interference patterns were generated using synchrotron X-rays. An improvement of the spatial resolution is also included in the project, and an X-ray interferometer designed for high-resolution phase-contrast X-ray imaging was fabricated and tested. In parallel with the instrumental developments, various soft tissues are observed by phase- contrast X-ray CT to find correspondence between the generated contrast and our histological knowledge. The observation done so far suggests that cancerous tissues are differentiated from normal tissues and that blood can produce phase contrast. Furthermore, this project includes exploring materials that modulate phase contrast for selective imaging.

A practical and efficient cellular substrate for the generation of induced pluripotent stem cells from adults: blood-derived endothelial progenitor cells.

PubMed

Geti, Imbisaat; Ormiston, Mark L; Rouhani, Foad; Toshner, Mark; Movassagh, Mehregan; Nichols, Jennifer; Mansfield, William; Southwood, Mark; Bradley, Allan; Rana, Amer Ahmed; Vallier, Ludovic; Morrell, Nicholas W

2012-12-01

Induced pluripotent stem cells (iPSCs) have the potential to generate patient-specific tissues for disease modeling and regenerative medicine applications. However, before iPSC technology can progress to the translational phase, several obstacles must be overcome. These include uncertainty regarding the ideal somatic cell type for reprogramming, the low kinetics and efficiency of reprogramming, and karyotype discrepancies between iPSCs and their somatic precursors. Here we describe the use of late-outgrowth endothelial progenitor cells (L-EPCs), which possess several favorable characteristics, as a cellular substrate for the generation of iPSCs. We have developed a protocol that allows the reliable isolation of L-EPCs from peripheral blood mononuclear cell preparations, including frozen samples. As a proof-of-principle for clinical applications we generated EPC-iPSCs from both healthy individuals and patients with heritable and idiopathic forms of pulmonary arterial hypertension. L-EPCs grew clonally; were highly proliferative, passageable, and bankable; and displayed higher reprogramming kinetics and efficiencies compared with dermal fibroblasts. Unlike fibroblasts, the high efficiency of L-EPC reprogramming allowed for the reliable generation of iPSCs in a 96-well format, which is compatible with high-throughput platforms. Array comparative genome hybridization analysis of L-EPCs versus donor-matched circulating monocytes demonstrated that L-EPCs have normal karyotypes compared with their subject's reference genome. In addition, >80% of EPC-iPSC lines tested did not acquire any copy number variations during reprogramming compared with their parent L-EPC line. This work identifies L-EPCs as a practical and efficient cellular substrate for iPSC generation, with the potential to address many of the factors currently limiting the translation of this technology.

Success factors for telehealth--a case study.

PubMed

Moehr, J R; Schaafsma, J; Anglin, C; Pantazi, S V; Grimm, N A; Anglin, S

2006-01-01

To present the lessons learned from an evaluation of a comprehensive telehealth project regarding success factors and evaluation methodology for such projects. A recent experience with the evaluation of new telehealth services in BC, Canada, is summarized. Two domains of clinical applications, as well as educational and administrative uses, and the project environment were evaluated. In order to contribute to the success of the project, the evaluation included formative and summative approaches employing qualitative and quantitative methods with data collection from telehealth events, participants and existing databases. The evaluation had to be carried out under severe budgetary and time constraints. We therefore deliberately chose a broad ranging exploratory approach within a framework provided, and generated questions to be answered on the basis of initial observations and participant driven interviews with progressively more focused and detailed data gathering, including perusal of a variety of existing data sources. A unique feature was an economic evaluation using static simulation models. The evaluation yielded rich and detailed data, which were able to explain a number of unanticipated findings. One clinical application domain was cancelled after 6 months, the other continues. The factors contributing to success include: Focus on chronic conditions which require visual information for proper management. Involvement of established teams in regular scheduled visits or in sessions scheduled well in advance. Problems arose with: Ad hoc applications, in particular under emergency conditions. Applications that disregard established referral patterns. Applications that support only part of a unit's services. The latter leads to the service mismatch dilemma (SMMD) with the end result that even those e-health services provided are not used. The problems encountered were compounded by issues arising from the manner in which the telehealth services had been introduced, in particular the lack of time for preparation and establishment of routine use. Educational applications had significant clinical benefits. Administrative applications generated savings which exceeded the substantial capital investment and made educational and clinical applications available at variable cost. Evaluation under severe constraints can yield rich information. The identified success factors, including provision of an overarching architecture and infrastructure, strong program management, thorough needs analysis and detailing applications to match the identified needs should improve the sustainability of e-health projects. Insights gained: Existing assumptions before the study was conducted: Evaluation has to proceed from identified questions according to a rigorous experimental design. Emergency and trauma services in remote regions can and should be supported via telehealth based on video-conferencing. Educational applications of telehealth directed at providers are beneficial for recruitment and retention of providers in remote areas. Insights gained by the study: An exploratory approach to evaluation using a multiplicity of methods can yield rich and detailed information even under severe constraints. Ad hoc and emergency clinical applications of telehealth can present problems unless they are based on thorough, detailed analyses of environment and need, conform to established practice patterns and rely on established trusting collaborative relationships. Less difficult applications should be introduced before attempting to support use under emergency conditions. Educational applications are of interest beyond the provider community to patients, family and community members, and have clinical value. In large, sparsely populated areas with difficult travel conditions administrative applications by themselves generate savings that compensate for the substantial capital investment for telehealth required for clinical applications.

A Short Review of the Generation of Molecular Descriptors and Their Applications in Quantitative Structure Property/Activity Relationships.

PubMed

Sahoo, Sagarika; Adhikari, Chandana; Kuanar, Minati; Mishra, Bijay K

2016-01-01

Synthesis of organic compounds with specific biological activity or physicochemical characteristics needs a thorough analysis of the enumerable data set obtained from literature. Quantitative structure property/activity relationships have made it simple by predicting the structure of the compound with any optimized activity. For that there is a paramount data set of molecular descriptors (MD). This review is a survey on the generation of the molecular descriptors and its probable applications in QSP/AR. Literatures have been collected from a wide class of research journals, citable web reports, seminar proceedings and books. The MDs were classified according to their generation. The applications of the MDs on the QSP/AR have also been reported in this review. The MDs can be classified into experimental and theoretical types, having a sub classification of the later into structural and quantum chemical descriptors. The structural parameters are derived from molecular graphs or topology of the molecules. Even the pixel of the molecular image can be used as molecular descriptor. In QSPR studies the physicochemical properties include boiling point, heat capacity, density, refractive index, molar volume, surface tension, heat of formation, octanol-water partition coefficient, solubility, chromatographic retention indices etc. Among biological activities toxicity, antimalarial activity, sensory irritant, potencies of local anesthetic, tadpole narcosis, antifungal activity, enzyme inhibiting activity are some important parameters in the QSAR studies. The classification of the MDs is mostly generic in nature. The application of the MDs in QSP/AR also has a generic link. Experimental MDs are more suitable in correlation analysis than the theoretical ones but are more expensive for generation. In advent of sophisticated computational tools and experimental design proliferation of MDs is inevitable, but for a highly optimized MD, studies on generation of MD is an unending process.

PoPLAR: Portal for Petascale Lifescience Applications and Research

PubMed Central

2013-01-01

Background We are focusing specifically on fast data analysis and retrieval in bioinformatics that will have a direct impact on the quality of human health and the environment. The exponential growth of data generated in biology research, from small atoms to big ecosystems, necessitates an increasingly large computational component to perform analyses. Novel DNA sequencing technologies and complementary high-throughput approaches--such as proteomics, genomics, metabolomics, and meta-genomics--drive data-intensive bioinformatics. While individual research centers or universities could once provide for these applications, this is no longer the case. Today, only specialized national centers can deliver the level of computing resources required to meet the challenges posed by rapid data growth and the resulting computational demand. Consequently, we are developing massively parallel applications to analyze the growing flood of biological data and contribute to the rapid discovery of novel knowledge. Methods The efforts of previous National Science Foundation (NSF) projects provided for the generation of parallel modules for widely used bioinformatics applications on the Kraken supercomputer. We have profiled and optimized the code of some of the scientific community's most widely used desktop and small-cluster-based applications, including BLAST from the National Center for Biotechnology Information (NCBI), HMMER, and MUSCLE; scaled them to tens of thousands of cores on high-performance computing (HPC) architectures; made them robust and portable to next-generation architectures; and incorporated these parallel applications in science gateways with a web-based portal. Results This paper will discuss the various developmental stages, challenges, and solutions involved in taking bioinformatics applications from the desktop to petascale with a front-end portal for very-large-scale data analysis in the life sciences. Conclusions This research will help to bridge the gap between the rate of data generation and the speed at which scientists can study this data. The ability to rapidly analyze data at such a large scale is having a significant, direct impact on science achieved by collaborators who are currently using these tools on supercomputers. PMID:23902523

Anaerobic biorefinery: Current status, challenges, and opportunities.

PubMed

Sawatdeenarunat, Chayanon; Nguyen, Duc; Surendra, K C; Shrestha, Shilva; Rajendran, Karthik; Oechsner, Hans; Xie, Li; Khanal, Samir Kumar

2016-09-01

Anaerobic digestion (AD) has been in use for many decades. To date, it has been primarily aimed at treating organic wastes, mainly manures and wastewater sludge, and industrial wastewaters. However, with the current advancements, a more open mind is required to look beyond these somewhat restricted original applications of AD. Biorefineries are such concepts, where multiple products including chemicals, fuels, polymers etc. are produced from organic feedstocks. The anaerobic biorefinery concept is now gaining increased attention, utilizing AD as the final disposal step. This review aims at evaluating the potential significance of anaerobic biorefineries, including types of feedstocks, uses for the produced energy, as well as sustainable applications of the generated residual digestate. A comprehensive analysis of various types of anaerobic biorefineries has been developed, including both large-scale and household level applications. Finally, future directives are highlighted showing how anaerobic biorefinery concept could impact the bioeconomy in the near future. Copyright © 2016 Elsevier Ltd. All rights reserved.

Recent Applications of Higher-Order Spectral Analysis to Nonlinear Aeroelastic Phenomena

NASA Technical Reports Server (NTRS)

Silva, Walter A.; Hajj, Muhammad R.; Dunn, Shane; Strganac, Thomas W.; Powers, Edward J.; Stearman, Ronald

2005-01-01

Recent applications of higher-order spectral (HOS) methods to nonlinear aeroelastic phenomena are presented. Applications include the analysis of data from a simulated nonlinear pitch and plunge apparatus and from F-18 flight flutter tests. A MATLAB model of the Texas A&MUniversity s Nonlinear Aeroelastic Testbed Apparatus (NATA) is used to generate aeroelastic transients at various conditions including limit cycle oscillations (LCO). The Gaussian or non-Gaussian nature of the transients is investigated, related to HOS methods, and used to identify levels of increasing nonlinear aeroelastic response. Royal Australian Air Force (RAAF) F/A-18 flight flutter test data is presented and analyzed. The data includes high-quality measurements of forced responses and LCO phenomena. Standard power spectral density (PSD) techniques and HOS methods are applied to the data and presented. The goal of this research is to develop methods that can identify the onset of nonlinear aeroelastic phenomena, such as LCO, during flutter testing.

Smartphone applications: potential tools for use in preparing for CCRN certification examinations.

PubMed

Curran, Claire

2014-06-01

Recent advances in smartphone technology now allow clinicians to use commercially produced applications when studying for nursing certification examinations. The quality of currently available CCRN review applications varies in this first generation of products. Most are limited to multiple-choice practice questions, although a few have additional elements such as study guides and reference charts. Weaknesses found in the applications evaluated include poorly written and edited content, questions limited to rote memorization rather than application and analysis of knowledge, and content too basic or outside the scope of experienced critical care nursing practice. A list of important factors for consumers to consider before purchase is provided. ©2014 American Association of Critical-Care Nurses.

Application of Spatial Data Modeling and Geographical Information Systems (GIS) for Identification of Potential Siting Options for Various Electrical Generation Sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mays, Gary T; Belles, Randy; Blevins, Brandon R

2012-05-01

Oak Ridge National Laboratory (ORNL) initiated an internal National Electric Generation Siting Study, which is an ongoing multiphase study addressing several key questions related to our national electrical energy supply. This effort has led to the development of a tool, OR-SAGE (Oak Ridge Siting Analysis for power Generation Expansion), to support siting evaluations. The objective in developing OR-SAGE was to use industry-accepted approaches and/or develop appropriate criteria for screening sites and employ an array of Geographic Information Systems (GIS) data sources at ORNL to identify candidate areas for a power generation technology application. The initial phase of the study examinedmore » nuclear power generation. These early nuclear phase results were shared with staff from the Electric Power Research Institute (EPRI), which formed the genesis and support for an expansion of the work to several other power generation forms, including advanced coal with carbon capture and storage (CCS), solar, and compressed air energy storage (CAES). Wind generation was not included in this scope of work for EPRI. The OR-SAGE tool is essentially a dynamic visualization database. The results shown in this report represent a single static set of results using a specific set of input parameters. In this case, the GIS input parameters were optimized to support an economic study conducted by EPRI. A single set of individual results should not be construed as an ultimate energy solution, since US energy policy is very complex. However, the strength of the OR-SAGE tool is that numerous alternative scenarios can be quickly generated to provide additional insight into electrical generation or other GIS-based applications. The screening process divides the contiguous United States into 100 x 100 m (1-hectare) squares (cells), applying successive power generation-appropriate site selection and evaluation criteria (SSEC) to each cell. There are just under 700 million cells representing the contiguous United States. If a cell meets the requirements of each criterion, the cell is deemed a candidate area for siting a specific power generation form relative to a reference plant for that power type. Some SSEC parameters preclude siting a power plant because of an environmental, regulatory, or land-use constraint. Other SSEC assist in identifying less favorable areas, such as proximity to hazardous operations. All of the selected SSEC tend to recommend against sites. The focus of the ORNL electrical generation source siting study is on identifying candidate areas from which potential sites might be selected, stopping short of performing any detailed site evaluations or comparisons. This approach is designed to quickly screen for and characterize candidate areas. Critical assumptions supporting this work include the supply of cooling water to thermoelectric power generation; a methodology to provide an adequate siting footprint for typical power plant applications; a methodology to estimate thermoelectric plant capacity while accounting for available cooling water; and a methodology to account for future ({approx}2035) siting limitations as population increases and demands on freshwater sources change. OR-SAGE algorithms were built to account for these critical assumptions. Stream flow is the primary thermoelectric plant cooling source evaluated in this study. All cooling was assumed to be provided by a closed-cycle cooling (CCC) system requiring makeup water to account for evaporation and blowdown. Limited evaluations of shoreline cooling and the use of municipal processed water (gray) cooling were performed. Using a representative set of SSEC as input to the OR-SAGE tool and employing the accompanying critical assumptions, independent results for the various power generation sources studied were calculated.« less

Next-generation sequencing for endocrine cancers: Recent advances and challenges.

PubMed

Suresh, Padmanaban S; Venkatesh, Thejaswini; Tsutsumi, Rie; Shetty, Abhishek

2017-05-01

Contemporary molecular biology research tools have enriched numerous areas of biomedical research that address challenging diseases, including endocrine cancers (pituitary, thyroid, parathyroid, adrenal, testicular, ovarian, and neuroendocrine cancers). These tools have placed several intriguing clues before the scientific community. Endocrine cancers pose a major challenge in health care and research despite considerable attempts by researchers to understand their etiology. Microarray analyses have provided gene signatures from many cells, tissues, and organs that can differentiate healthy states from diseased ones, and even show patterns that correlate with stages of a disease. Microarray data can also elucidate the responses of endocrine tumors to therapeutic treatments. The rapid progress in next-generation sequencing methods has overcome many of the initial challenges of these technologies, and their advantages over microarray techniques have enabled them to emerge as valuable aids for clinical research applications (prognosis, identification of drug targets, etc.). A comprehensive review describing the recent advances in next-generation sequencing methods and their application in the evaluation of endocrine and endocrine-related cancers is lacking. The main purpose of this review is to illustrate the concepts that collectively constitute our current view of the possibilities offered by next-generation sequencing technological platforms, challenges to relevant applications, and perspectives on the future of clinical genetic testing of patients with endocrine tumors. We focus on recent discoveries in the use of next-generation sequencing methods for clinical diagnosis of endocrine tumors in patients and conclude with a discussion on persisting challenges and future objectives.

Lead telluride as a thermoelectric material for thermoelectric power generation

NASA Astrophysics Data System (ADS)

Dughaish, Z. H.

2002-09-01

The specialized applications of thermoelectric generators are very successful and have motivated a search for materials with an improved figure of merit Z, and also for materials which operate at elevated temperatures. Lead telluride, PbTe, is an intermediate thermoelectric power generator. Its maximum operating temperature is 900 K. PbTe has a high melting point, good chemical stability, low vapor pressure and good chemical strength in addition to high figure of merit Z. Recently, research in thermoelectricity aims to obtain new improved materials for autonomous sources of electrical power in specialized medical, terrestial and space applications and to obtain an unconventional energy source after the oil crises of 1974. Although the efficiency of thermoelectric generators is rather low, typically ∼5%, the other advantages, such as compactness, silent, reliability, long life, and long period of operation without attention, led to a wide range of applications. PbTe thermoelectric generators have been widely used by the US army, in space crafts to provide onboard power, and in pacemakers batteries. The general physical properties of lead telluride and factors affecting the figure of merit have been reviewed. Various possibilities of improving the figure of merit of the material have been given, including effect of grain size on reducing the lattice thermal conductivity λL. Comparison of some transport properties of lead telluride with other thermoelectric materials and procedures of preparing compacts with transport properties very close to the single crystal values from PbTe powder by cold and hot-pressing techniques are discussed.

Computerized symbolic manipulation in structural mechanics Progress and potential

NASA Technical Reports Server (NTRS)

Noor, A. K.; Andersen, C. M.

1978-01-01

Status and recent applications of computerized symbolic manipulation to structural mechanics problems are summarized. The applications discussed include; (1) generation of characteristic arrays of finite elements; (2) evaluation of effective stiffness and mass coefficients of continuum models for repetitive lattice structures; and (3) application of Rayleigh-Ritz technique to free vibration analysis of laminated composite elliptic plates. The major advantages of using computerized symbolic manipulation in each of these applications are outlined. A number of problem areas which limit the realization of the full potential of computerized symbolic manipulation in structural mechanics are examined and some of the means of alleviating them are discussed.

Next generation laser for Inertial Confinement Fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marshall, C.D.; Beach, J.; Bibeau, C.

1997-07-18

We are in the process of developing and building the ``Mercury`` laser system as the first in a series of a new generation of diode-pumped solid-state Inertial Confinement Fusion (ICF) lasers at LLNL. Mercury will be the first integrated demonstration of a scalable laser architecture compatible with advanced high energy density (HED) physics applications. Primary performance goals include 10% efficiencies at 10 Hz and a 1-10 ns pulse with 1{omega} energies of 100 J and with 2{omega}/3{omega} frequency conversion.

The solution of the optimization problem of small energy complexes using linear programming methods

NASA Astrophysics Data System (ADS)

Ivanin, O. A.; Director, L. B.

2016-11-01

Linear programming methods were used for solving the optimization problem of schemes and operation modes of distributed generation energy complexes. Applicability conditions of simplex method, applied to energy complexes, including installations of renewable energy (solar, wind), diesel-generators and energy storage, considered. The analysis of decomposition algorithms for various schemes of energy complexes was made. The results of optimization calculations for energy complexes, operated autonomously and as a part of distribution grid, are presented.

The Use of Social Media Networks and Mobile Phone Applications for Reporting Suspicious and Criminal Activities to Mass Transit Law Enforcement Agencies

DTIC Science & Technology

2013-12-01

Media (IACP defines Social Media as the following:2  A category of Internet-based resources that integrate user - generated content and user ...Social Media—a category of Internet –based resources that integrate user - generated content and user participations. Includes Facebook, MySpace...reduction in crime is unresolved, warranting future study in this area. vi THIS PAGE INTENTIONALLY LEFT BLANK vii TABLE OF CONTENTS I. INTRODUCTION

Vibro-acoustics for Space Station applications

NASA Technical Reports Server (NTRS)

Vaicaitis, R.; Bofilios, D. A.

1986-01-01

An analytical procedure has been developed to study noise generation in a double wall and single wall cylindrical shell due to mechanical point loads. The objective of this study is to develop theoretical procedures for parametetric evaluation of noise generation andd noise transmission for the habitability modules of the proposed Space Station operation. The solutions of the governing acoustic-structural equations are obtained utilizing modal decomposition. The numerical results include modal frequencies, deflection response spectral densities and interior noise sound pressure levels.

Development of approaches to a third-generation carbohydrate-conjugate vaccine against Streptococcus pneumoniae: the search for optimal oligosaccharide ligands

NASA Astrophysics Data System (ADS)

Gening, M. L.; Kurbatova, E. A.; Tsvetkov, Yu E.; Nifantiev, N. E.

2015-11-01

The review addresses the application of synthetic oligosaccharides related to fragments of capsular polysaccharides from different serotypes of the bacterium Streptococcus pneumoniae for the design of third-generation pneumococcal conjugate vaccines. Special focus is given to characteristic features of the chemical structures of oligosaccharides required for the induction of the protective immune response when using synthetic glycoconjugate vaccines based on oligosaccharide ligands and carrier proteins. The bibliography includes 101 references.

Applications for fiber optic sensing in the upstream oil and gas industry

NASA Astrophysics Data System (ADS)

Baldwin, Chris S.

2015-05-01

Fiber optic sensing has been used in an increasing number of applications in the upstream oil and gas industry over the past 20 years. In some cases, fiber optic sensing is providing measurements where traditional measurement technologies could not. This paper will provide a general overview of these applications and describe how the use of fiber optic sensing is enabling these applications. Technologies such as Bragg gratings, distributed temperature and acoustic sensing, interferometric sensing, and Brillouin scattering will be discussed. Applications for optic sensing include a range of possibilities from a single pressure measurement point in the wellbore to multizone pressure and flow monitoring. Some applications make use of fully distributed measurements including thermal profiling of the well. Outside of the wellbore, fiber optic sensors are used in applications for flowline and pipeline monitoring and for riser integrity monitoring. Applications to be described in this paper include in-flow profiling, well integrity, production monitoring, and steam chamber growth. These applications will cover well types such as injectors, producers, hydraulic fracturing, and thermal recovery. Many of these applications use the measurements provided by fiber optic sensing to improve enhanced oil recovery operations. The growing use of fiber optic sensors is providing improved measurement capabilities leading to the generation of actionable data for enhanced production optimization. This not only increases the recovered amount of production fluids but can also enhance wellbore integrity and safety.

Computer Generated Holography with Intensity-Graded Patterns

PubMed Central

Conti, Rossella; Assayag, Osnath; de Sars, Vincent; Guillon, Marc; Emiliani, Valentina

2016-01-01

Computer Generated Holography achieves patterned illumination at the sample plane through phase modulation of the laser beam at the objective back aperture. This is obtained by using liquid crystal-based spatial light modulators (LC-SLMs), which modulate the spatial phase of the incident laser beam. A variety of algorithms is employed to calculate the phase modulation masks addressed to the LC-SLM. These algorithms range from simple gratings-and-lenses to generate multiple diffraction-limited spots, to iterative Fourier-transform algorithms capable of generating arbitrary illumination shapes perfectly tailored on the base of the target contour. Applications for holographic light patterning include multi-trap optical tweezers, patterned voltage imaging and optical control of neuronal excitation using uncaging or optogenetics. These past implementations of computer generated holography used binary input profile to generate binary light distribution at the sample plane. Here we demonstrate that using graded input sources, enables generating intensity graded light patterns and extend the range of application of holographic light illumination. At first, we use intensity-graded holograms to compensate for LC-SLM position dependent diffraction efficiency or sample fluorescence inhomogeneity. Finally we show that intensity-graded holography can be used to equalize photo evoked currents from cells expressing different levels of chanelrhodopsin2 (ChR2), one of the most commonly used optogenetics light gated channels, taking into account the non-linear dependence of channel opening on incident light. PMID:27799896

Parallel fabrication of macroporous scaffolds.

PubMed

Dobos, Andrew; Grandhi, Taraka Sai Pavan; Godeshala, Sudhakar; Meldrum, Deirdre R; Rege, Kaushal

2018-07-01

Scaffolds generated from naturally occurring and synthetic polymers have been investigated in several applications because of their biocompatibility and tunable chemo-mechanical properties. Existing methods for generation of 3D polymeric scaffolds typically cannot be parallelized, suffer from low throughputs, and do not allow for quick and easy removal of the fragile structures that are formed. Current molds used in hydrogel and scaffold fabrication using solvent casting and porogen leaching are often single-use and do not facilitate 3D scaffold formation in parallel. Here, we describe a simple device and related approaches for the parallel fabrication of macroporous scaffolds. This approach was employed for the generation of macroporous and non-macroporous materials in parallel, in higher throughput and allowed for easy retrieval of these 3D scaffolds once formed. In addition, macroporous scaffolds with interconnected as well as non-interconnected pores were generated, and the versatility of this approach was employed for the generation of 3D scaffolds from diverse materials including an aminoglycoside-derived cationic hydrogel ("Amikagel"), poly(lactic-co-glycolic acid) or PLGA, and collagen. Macroporous scaffolds generated using the device were investigated for plasmid DNA binding and cell loading, indicating the use of this approach for developing materials for different applications in biotechnology. Our results demonstrate that the device-based approach is a simple technology for generating scaffolds in parallel, which can enhance the toolbox of current fabrication techniques. © 2018 Wiley Periodicals, Inc.

Operational recovery of turbine No. 3 at Potomac Edison`s Dam No. 4 hydrogenerating facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pelczar, R.S.

1995-12-31

The Potomac Edison Dam No. 4 hydroelectric generating station is a historic, turn of the century facility located on the Potomac River near Shepherdstown, West Virginia. The station, originally constructed in 1909, employed twin horizontal Francis hydroturbine generating systems. The systems are unique in that the turbines and generators are offset 37 feet, interconnected by rope and sheaves. In May 1989 a third vertical open flume turbine generating system was added to make use of available site capacity. Both the turbine and speed increaser were the largest products developed by their respective manufacturers for a hydro turbine-generator application. This papermore » will review the subsequent operational experience which led to the original speed increaser failure on unit No. 3 and replacement of the drive system including special design considerations to the replacement speed increaser and its support structure. Specific design challenges included: (1) Designing and implementing a reliable configuration. (2) Reducing operational sound levels. (3) Minimizing harmful structure-borne vibrations which were affecting the internal rotating elements. (4) Incorporating a system brake for emergency and service purposes.« less

Ngi and Internet2: accelerating the creation of tomorrow's internet.

PubMed

Kratz, M; Ackerman, M; Hanss, T; Corbato, S

2001-01-01

Internet2 is a consortium of leading U.S. universities working in partnership with industry and the U.S. government's Next Generation Internet (NGI) initiative to develop a faster, more reliable Internet for research and education including enhanced, high-performance networking services and the advanced applications that are enabled by those services [1]. By facilitating and coordinating the development, deployment, operation, and technology transfer of advanced, network-based applications and network services, Internet2 and NGI are working together to fundamentally change the way scientists, engineers, clinicians, and others work together. [http://www.internet2.edu] The NGI Program has three tracks: research, network testbeds, and applications. The aim of the research track is to promote experimentation with the next generation of network technologies. The network testbed track aims to develop next generation network testbeds to connect universities and federal research institutions at speeds that are sufficient to demonstrate new technologies and support future research. The aim of the applications track is to demonstrate new applications, enabled by the NGI networks, to meet important national goals and missions [2]. [http://www.ngi.gov/] The Internet2/NGI backbone networks, Abilene and vBNS (very high performance Backbone Network Service), provide the basis of collaboration and development for a new breed of advanced medical applications. Academic medical centers leverage the resources available throughout the Internet2 high-performance networking community for high-capacity broadband and selectable quality of service to make effective use of national repositories. The Internet2 Health Sciences Initiative enables a new generation of emerging medical applications whose architecture and development have been restricted by or are beyond the constraints of traditional Internet environments. These initiatives facilitate a variety of activities to foster the development and deployment of emerging applications that meet the requirements of clinical practice, medical and related biological research, education, and medical awareness throughout the public sector. Medical applications that work with high performance networks and supercomputing capabilities offer exciting new solutions for the medical industry. Internet2 and NGI,strive to combine the expertise of their constituents to establish a distributed knowledge system for achieving innovation in research, teaching, learning, and clinical care.

New V and V Tools for Diagnostic Modeling Environment (DME)

NASA Technical Reports Server (NTRS)

Pecheur, Charles; Nelson, Stacy; Merriam, Marshall (Technical Monitor)

2002-01-01

The purpose of this report is to provide correctness and reliability criteria for verification and validation (V&V) of Second Generation Reusable Launch Vehicle (RLV) Diagnostic Modeling Environment, describe current NASA Ames Research Center tools for V&V of Model Based Reasoning systems, and discuss the applicability of Advanced V&V to DME. This report is divided into the following three sections: (1) correctness and reliability criteria; (2) tools for V&V of Model Based Reasoning; and (3) advanced V&V applicable to DME. The Executive Summary includes an overview of the main points from each section. Supporting details, diagrams, figures, and other information are included in subsequent sections. A glossary, acronym list, appendices, and references are included at the end of this report.

40 CFR 262.102 - What special definitions are included in this subpart?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE University... particularly hazardous substances as designated in a University's Chemical Hygiene Plan under OSHA, or... Management Plan (EMP) means a written program developed and implemented by the university which sets forth...

40 CFR 86.1801-12 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... emission standards in this subpart, including carbon dioxide (CO2), nitrous oxide (N2O), and methane (CH4... eligible to generate greenhouse gas emission credits for their 2012 model year production, after the... production of that manufacturer. (1) Eligibility requirements. Eligibility as determined in this paragraph (k...

PSYCHOLOGICAL FOUNDATIONS OF ADULT EDUCATION.

ERIC Educational Resources Information Center

LANYON, RICHARD I.; SCHWARTZ, MILTON M.

TWO PAPERS ARE INCLUDED IN THIS BULLETIN. THE MILTON SCHWARTZ PAPER, "THEORIES OF MOTIVATION AND THEIR APPLICATION TO ADULT EDUCATION," SURVEYS THE THINKING, RESEARCH, AND CONCLUSIONS OF SOME OF THE LEADING FIGURES CONCERNED WITH SOCIAL MOTIVATION. THE AUTHOR ATTEMPTS TO CLASSIFY THESE THEORIES BY GENERATING A TWO-DIMENSIONAL SCHEMA OF…

The World in a Tomato: Revisiting the Use of "Codes" in Freire's Problem-Posing Education.

ERIC Educational Resources Information Center

Barndt, Deborah

1998-01-01

Gives examples of the use of Freire's notion of codes or generative themes in problem-posing literacy education. Describes how these applications expand Freire's conceptions by involving students in code production, including multicultural perspectives, and rethinking codes as representations. (SK)

Compulsory Birth Control and Fertility Measures in India.

ERIC Educational Resources Information Center

Halli, S. S.

1983-01-01

Discussion of possible applications of the microsimulation approach to analysis of population policy proposes compulsory sterilization policy for all of India. Topics covered include India's population problem, methods for generating a distribution of couples to be sterilized, model validation, data utilized, data analysis, program limitations,…

Nuclear Education and Training Programs of Potential Interest to Utilities.

ERIC Educational Resources Information Center

Atomic Energy Commission, Washington, DC.

This compilation of education and training programs related to nuclear applications in electric power generation covers programs conducted by nuclear reactor vendors, public utilities, universities, technical institutes, and community colleges, which were available in December 1968. Several training-program consultant services are also included.…

Classical evolution and quantum generation in generalized gravity theories including string corrections and tachyons: Unified analyses

NASA Astrophysics Data System (ADS)

Hwang, Jai-Chan; Noh, Hyerim

2005-03-01

We present cosmological perturbation theory based on generalized gravity theories including string theory correction terms and a tachyonic complication. The classical evolution as well as the quantum generation processes in these varieties of gravity theories are presented in unified forms. These apply both to the scalar- and tensor-type perturbations. Analyses are made based on the curvature variable in two different gauge conditions often used in the literature in Einstein’s gravity; these are the curvature variables in the comoving (or uniform-field) gauge and the zero-shear gauge. Applications to generalized slow-roll inflation and its consequent power spectra are derived in unified forms which include a wide range of inflationary scenarios based on Einstein’s gravity and others.

Drag Reduction Devices for Aircraft (Latest Citations from the Aerospace Database)

NASA Technical Reports Server (NTRS)

1996-01-01

The bibliography contains citations concerning the modeling, application, testing, and development of drag reduction devices for aircraft. Slots, flaps, fences, large-eddy breakup (LEBU) devices, vortex generators and turbines, Helmholtz resonators, and winglets are among the devices discussed. Contour shaping to ensure laminar flow, control boundary layer transition, or minimize turbulence is also covered. Applications include the wings, nacelles, fuselage, empennage, and externals of aircraft designed for high-lift, subsonic, or supersonic operation. The design, testing, and development of directional grooves, commonly called riblets, are covered in a separate bibliography.(Contains 50-250 citations and includes a subject term index and title list.)

Radar Remote Sensing

NASA Technical Reports Server (NTRS)

Rosen, Paul A.

2012-01-01

This lecture was just a taste of radar remote sensing techniques and applications. Other important areas include Stereo radar grammetry. PolInSAR for volumetric structure mapping. Agricultural monitoring, soil moisture, ice-mapping, etc. The broad range of sensor types, frequencies of observation and availability of sensors have enabled radar sensors to make significant contributions in a wide area of earth and planetary remote sensing sciences. The range of applications, both qualitative and quantitative, continue to expand with each new generation of sensors.

Adaption of unstructured meshes using node movement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carpenter, J.G.; McRae, V.D.S.

1996-12-31

The adaption algorithm of Benson and McRae is modified for application to unstructured grids. The weight function generation was modified for application to unstructured grids and movement was limited to prevent cross over. A NACA 0012 airfoil is used as a test case to evaluate the modified algorithm when applied to unstructured grids and compared to results obtained by Warren. An adaptive mesh solution for the Sudhoo and Hall four element airfoil is included as a demonstration case.

Analytical applications of microbial fuel cells. Part I: Biochemical oxygen demand.

PubMed

Abrevaya, Ximena C; Sacco, Natalia J; Bonetto, Maria C; Hilding-Ohlsson, Astrid; Cortón, Eduardo

2015-01-15

Microbial fuel cells (MFCs) are bio-electrochemical devices, where usually the anode (but sometimes the cathode, or both) contains microorganisms able to generate and sustain an electrochemical gradient which is used typically to generate electrical power. In the more studied set-up, the anode contains heterotrophic bacteria in anaerobic conditions, capable to oxidize organic molecules releasing protons and electrons, as well as other by-products. Released protons could reach the cathode (through a membrane or not) whereas electrons travel across an external circuit originating an easily measurable direct current flow. MFCs have been proposed fundamentally as electric power producing devices or more recently as hydrogen producing devices. Here we will review the still incipient development of analytical uses of MFCs or related devices or set-ups, in the light of a non-restrictive MFC definition, as promising tools to asset water quality or other measurable parameters. An introduction to biological based analytical methods, including bioassays and biosensors, as well as MFCs design and operating principles, will also be included. Besides, the use of MFCs as biochemical oxygen demand sensors (perhaps the main analytical application of MFCs) is discussed. In a companion review (Part 2), other new analytical applications are reviewed used for toxicity sensors, metabolic sensors, life detectors, and other proposed applications. Copyright © 2014 Elsevier B.V. All rights reserved.

Industrial Applications of Pulsed Power Technology

NASA Astrophysics Data System (ADS)

Takaki, Koichi; Katsuki, Sunao

Recent progress of the industrial applications of pulsed power is reviewed in this paper. Repetitively operated pulsed power generators with a moderate peak power have been developed for industrial applications. These generators are reliable and low maintenance. Development of the pulsed power generators helps promote industrial applications of pulsed power for such things as food processing, medical treatment, water treatment, exhaust gas treatment, ozone generation, engine ignition, ion implantation and others. Here, industrial applications of pulsed power are classified by application for biological effects, for pulsed streamer discharges in gases, for pulsed discharges in liquid or liquid-mixture, and for bright radiation sources.

Magnetic nanoparticles: reactive oxygen species generation and potential therapeutic applications

NASA Astrophysics Data System (ADS)

Mai, Trang; Hilt, J. Zach

2017-07-01

Magnetic nanoparticles have been demonstrated to produce reactive oxygen species (ROS), which play a major role in various cellular pathways, via Fenton and Haber-Weiss reaction. ROS act as a double-edged sword inside the body. At normal conditions, the generation of ROS is in balance with their elimination by scavenger systems, and they can promote cell proliferation as well as differentiation. However, at an increased level, they can cause damages to protein, lead to cellular apoptosis, and contribute to many diseases including cancer. Many recent studies proposed a variety of strategies to either suppress toxicity of ROS generation or exploit the elevated ROS levels for cancer therapy.

Magnetoencephalography - a noninvasive brain imaging method with 1 ms time resolution

NASA Astrophysics Data System (ADS)

DelGratta, Cosimo; Pizzella, Vittorio; Tecchio, Franca; Luca Romani, Gian

2001-12-01

The basics of magnetoencephalography (MEG), i.e. the measurement and the analysis of the tiny magnetic fields generated outside the scalp by the working human brain, are reviewed. Three main topics are discussed: (1) the relationship between the magnetic field and its generators, including on one hand the neurophysiological basis and the physical theory of magnetic field generation, and on the other hand the techniques for the estimation of the sources from the magnetic field measurements; (2) the instrumental techniques and the laboratory practice of neuromagnetic field measurement and (3) the main applications of MEG in basic neurophysiology as well as in clinical neurology.

S3D: An interactive surface grid generation tool

NASA Technical Reports Server (NTRS)

Luh, Raymond Ching-Chung; Pierce, Lawrence E.; Yip, David

1992-01-01

S3D, an interactive software tool for surface grid generation, is described. S3D provides the means with which a geometry definition based either on a discretized curve set or a rectangular set can be quickly processed towards the generation of a surface grid for computational fluid dynamics (CFD) applications. This is made possible as a result of implementing commonly encountered surface gridding tasks in an environment with a highly efficient and user friendly graphical interface. Some of the more advanced features of S3D include surface-surface intersections, optimized surface domain decomposition and recomposition, and automated propagation of edge distributions to surrounding grids.

Military and Government Applications of Human-Machine Communication by Voice

NASA Astrophysics Data System (ADS)

Weinstein, Clifford J.

1995-10-01

This paper describes a range of opportunities for military and government applications of human-machine communication by voice, based on visits and contacts with numerous user organizations in the United States. The applications include some that appear to be feasible by careful integration of current state-of-the-art technology and others that will require a varying mix of advances in speech technology and in integration of the technology into applications environments. Applications that are described include (1) speech recognition and synthesis for mobile command and control; (2) speech processing for a portable multifunction soldier's computer; (3) speech- and language-based technology for naval combat team tactical training; (4) speech technology for command and control on a carrier flight deck; (5) control of auxiliary systems, and alert and warning generation, in fighter aircraft and helicopters; and (6) voice check-in, report entry, and communication for law enforcement agents or special forces. A phased approach for transfer of the technology into applications is advocated, where integration of applications systems is pursued in parallel with advanced research to meet future needs.

A normative price for energy from an electricity generation system: An Owner-dependent Methodology for Energy Generation (system) Assessment (OMEGA). Volume 1: Summary

NASA Technical Reports Server (NTRS)

Chamberlain, R. G.; Mcmaster, K. M.

1981-01-01

The utility owned solar electric system methodology is generalized and updated. The net present value of the system is determined by consideration of all financial benefits and costs (including a specified return on investment). Life cycle costs, life cycle revenues, and residual system values are obtained. Break even values of system parameters are estimated by setting the net present value to zero. While the model was designed for photovoltaic generators with a possible thermal energy byproduct, it applicability is not limited to such systems. The resulting owner-dependent methodology for energy generation system assessment consists of a few equations that can be evaluated without the aid of a high-speed computer.

UV-fibers: two decades of improvements for new applications

NASA Astrophysics Data System (ADS)

Klein, Karl-Friedrich; Khalilov, Valery K.

2015-03-01

Multimode UV-fibers with high-OH synthetic silica core and F-doped silica cladding have been available for over 40 years. At the beginning, the spectral UV-range above 250 nm wavelength was commonly used, because the generation of UV-absorbing defect centers prevented reliable light transfer below 250 nm; even light from a low-power broadband deuterium-lamp was sufficient to damage these UV-fibers of the 1st generation. However, even then, applications in the field of spectroscopy, laser light delivery, sensors and process control were discussed and improvements of fiber quality in this very interesting UVC range required by researchers and industrial end-users. Starting in 1993 with hydrogen-loaded fibers, further modification in preform and fiber manufacturing including additional fiber treatments lead to currently available hydrogen-free UV-fiber (4th generation) with significantly improved stability in the UVC, enabling routine use of optical fibers in this field. In addition to the UV-fiber improvements, some selected UV fiber-optic applications using broadband deuterium-lamps will be discussed. Finally, there is still room for further improvements, especially in combination with newly available pulsed UV light sources, which are low-cost, small sized and highly reliable.

Hybrid Power Management Program Evaluated Ultracapacitors for the Next Generation Launch Transportation Project

NASA Technical Reports Server (NTRS)

Eichenberg, Dennis J.

2005-01-01

The NASA Glenn Research Center initiated baseline testing of ultracapacitors to obtain empirical data in determining the feasibility of using ultracapacitors for the Next Generation Launch Transportation (NGLT) Project. There are large transient loads associated with NGLT that require a very large primary energy source or an energy storage system. The primary power source used for this test was a proton-exchange-membrane (PEM) fuel cell. The energy storage system can consist of batteries, flywheels, or ultracapacitors. Ultracapacitors were used for these tests. NASA Glenn has a wealth of experience in ultracapacitor technology through the Hybrid Power Management (HPM) Program, which the Avionics, Power and Communications Branch of Glenn s Engineering Development Division initiated for the Technology Transfer and Partnership Office. HPM is the innovative integration of diverse, state-ofthe- art power devices in optimal configurations for space and terrestrial applications. The appropriate application and control of the various advanced power devices (such as ultracapacitors and fuel cells) significantly improves overall system performance and efficiency. HPM has extremely wide potential. Applications include power generation, transportation systems, biotechnology systems, and space power systems. HPM has the potential to significantly alleviate global energy concerns, improve the environment, and stimulate the economy.

DNA methylation data analysis and its application to cancer research

PubMed Central

Ma, Xiaotu; Wang, Yi-Wei; Zhang, Michael Q; Gazdar, Adi F

2013-01-01

With the rapid development of genome-wide high-throughput technologies, including expression arrays, SNP arrays and next-generation sequencing platforms, enormous amounts of molecular data have been generated and deposited in the public domain. The application of computational approaches is required to yield biological insights from this enormous, ever-growing resource. A particularly interesting subset of these resources is related to epigenetic regulation, with DNA methylation being the most abundant data type. In this paper, we will focus on the analysis of DNA methylation data and its application to cancer studies. We first briefly review the molecular techniques that generate such data, much of which has been obtained with the use of the most recent version of Infinium HumanMethylation450 BeadChip® technology (Illumina, CA, USA). We describe the coverage of the methylome by this technique. Several examples of data mining are provided. However, it should be understood that reliance on a single aspect of epigenetics has its limitations. In the not too distant future, these defects may be rectified, providing scientists with previously unavailable opportunities to explore in detail the role of epigenetics in cancer and other disease states. PMID:23750645

Evaluation of High-Performance Space Nuclear Electric Generators for Electric Propulsion Application

NASA Technical Reports Server (NTRS)

Woodcock, Gordon; Kross, Dennis A. (Technical Monitor)

2002-01-01

Electric propulsion applications are enhanced by high power-to-mass ratios for their electric power sources. At multi-megawatt levels, we can expect thrust production systems to be less than 5 kg/kWe. Application of nuclear electric propulsion to human Mars missions becomes an attractive alternative to nuclear thermal propulsion if the propulsion system is less than about 10 kg/kWe. Recent references have projected megawatt-plus nuclear electric sources at specific mass values from less than 1 kg/kWe to about 5 kg/kWe. Various assumptions are made regarding power generation cycle (turbogenerator; MHD (magnetohydrodynamics)) and reactor heat source design. The present paper compares heat source and power generation options on the basis of a parametric model that emphasizes heat transfer design and realizable hardware concept. Pressure drop (important!) is included in the power cycle analysis, and MHD and turbogenerator cycles are compared. Results indicate that power source specific mass less than 5 kg/kWe is attainable, even if peak temperatures achievable are limited to 1500 K. Projections of specific mass less than 1 kg/kWe are unrealistic, even at the highest peak temperatures considered.

Software Template for Instruction in Mathematics

NASA Technical Reports Server (NTRS)

Shelton, Robert O.; Moebes, Travis A.; Beall, Anna

2005-01-01

Intelligent Math Tutor (IMT) is a software system that serves as a template for creating software for teaching mathematics. IMT can be easily connected to artificial-intelligence software and other analysis software through input and output of files. IMT provides an easy-to-use interface for generating courses that include tests that contain both multiple-choice and fill-in-the-blank questions, and enables tracking of test scores. IMT makes it easy to generate software for Web-based courses or to manufacture compact disks containing executable course software. IMT also can function as a Web-based application program, with features that run quickly on the Web, while retaining the intelligence of a high-level language application program with many graphics. IMT can be used to write application programs in text, graphics, and/or sound, so that the programs can be tailored to the needs of most handicapped persons. The course software generated by IMT follows a "back to basics" approach of teaching mathematics by inducing the student to apply creative mathematical techniques in the process of learning. Students are thereby made to discover mathematical fundamentals and thereby come to understand mathematics more deeply than they could through simple memorization.

"First generation" automated DNA sequencing technology.

PubMed

Slatko, Barton E; Kieleczawa, Jan; Ju, Jingyue; Gardner, Andrew F; Hendrickson, Cynthia L; Ausubel, Frederick M

2011-10-01

Beginning in the 1980s, automation of DNA sequencing has greatly increased throughput, reduced costs, and enabled large projects to be completed more easily. The development of automation technology paralleled the development of other aspects of DNA sequencing: better enzymes and chemistry, separation and imaging technology, sequencing protocols, robotics, and computational advancements (including base-calling algorithms with quality scores, database developments, and sequence analysis programs). Despite the emergence of high-throughput sequencing platforms, automated Sanger sequencing technology remains useful for many applications. This unit provides background and a description of the "First-Generation" automated DNA sequencing technology. It also includes protocols for using the current Applied Biosystems (ABI) automated DNA sequencing machines. © 2011 by John Wiley & Sons, Inc.

Probing Dynamic Cell-Substrate Interactions using Photochemically Generated Surface-Immobilized Gradients: Application to Selectin-Mediated Leukocyte Rolling

PubMed Central

Herman, Christine T.; Potts, Gregory K.; Michael, Madeline C.; Tolan, Nicole V.

2014-01-01

Model substrates presenting biochemical cues immobilized in a controlled and well-defined manner are of great interest for their applications in biointerface studies that elucidate the molecular basis of cell receptor-ligand interactions. Herein, we describe a direct, photochemical method to generate one-component surface-immobilized biomolecular gradients that are applied to the study of selectin-mediated leukocyte rolling. The technique employs benzophenone-modified glass substrates, which upon controlled exposure to UV light (350 – 365 nm) in the presence of protein-containing solutions facilitate the generation of covalently immobilized protein gradients. Conditions were optimized to generate gradient substrates presenting P-selectin and PSGL-1 (P-selectin Glycoprotein Ligand-1) immobilized at site densities over a 5- to 10-fold range (from as low as ~200 molecules/μm2 to as high as 6000 molecules/μm2). The resulting substrates were quantitatively characterized via fluorescence analysis and radioimmunoassays before their use in the leukocyte rolling assays. HL-60 promyelocytes and Jurkat T lymphocytes were assessed for their ability to tether to and roll on substrates presenting immobilized P-selectin and PSGL-1 under conditions of physiologically relevant shear stress. The results of these flow assays reveal the combined effect of immobilized protein site density and applied wall shear stress on cell rolling behavior. Two-component substrates presenting P-selectin and ICAM-1 (intercellular adhesion molecule-1) were also generated to assess the interplay between these two proteins and their effect on cell rolling and adhesion. These proof-of-principle studies verify that the described gradient generation approach yields well-defined gradient substrates that present immobilized proteins over a large range of site densities that are applicable for investigation of cell-materials interactions, including multi-parameter leukocyte flow studies. Future applications of this enabling methodology may lead to new insights into the biophysical phenomena and molecular mechanism underlying complex biological processes such as leukocyte recruitment and the inflammatory response. PMID:21614364

Applications of High-Frequency Gravitational Waves to the Global War on Terror

NASA Astrophysics Data System (ADS)

Baker, Robert M. L.

2010-01-01

Applications of high-frequency gravitational waves or HFGWs to the global war on terror are now realistic because technology developed by GravWave® LLC and other institutions overseas can lead to devices, some already constructed, that can generate and detect HFGWs. In fact, three HFGW detectors have been built outside the United States and an ultra high-sensitive Li-Baker HFGW Detector has been proposed. HFGW generators have been proposed theoretically by the Russians, Germans, Italians and Chinese. Because of their unique characteristics, such as their ability to pass through all material without attenuation, HFGWs could be utilized for uninterruptible, very low-probability-of-intercept (LPI), high-bandwidth communications among and between anti-terrorist assets. One such communications system, which can be constructed from off-the-shelf elements, is discussed. The HFGW generation device or transmitter alternative selected is based upon bands of piezoelectric crystal, film-bulk acoustic resonators or FBARs energized by conventional Magnetrons. The system is theoretically capable of transmitting and detecting, through use of the Li-Baker HFGW detector, a signal generated on the opposite side of the Earth. Although HFGWs do not interact with and are not absorbed by ordinary matter, their presence can be detected by their distortion of spacetime as measured by the Laser Interferometer Gravitational Observatory (LIGO), Virgo, GEO600, et al., by detection photons generated from electromagnetic beams having the same frequency, direction and phase as the HFGWs in a superimposed magnetic field (Li-Baker HFGW Detector), by the change in polarization HFGWs produce in a microwave guide (Birmingham University Detector) and by other such instruments. Potential theoretical applications, which may or may not be practical yet theoretically possible, are propulsion, including "moving" space objects such as missiles, anti-missiles and warheads in flight; surveillance through buildings and the Earth itself and remote initiation of nuclear events. Such applications can only be quantified and established as practical by the proof-of-concept generation and detection of HFGWs in the laboratory experiment. These important potential HFGW applications are motivations for HFGW research and development and such an R&D program is recommended for immediate initiation.

77 FR 70158 - Combined Notice of Filings #2

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-23

.... Comments Due: 5 p.m. ET 12/6/12. Docket Numbers: ER13-383-000. Applicants: Alcoa Power Generating Inc...-5096. Comments Due: 5 p.m. ET 12/6/12. Docket Numbers: ER13-384-000. Applicants: Alcoa Power Generating...: ER13-387-000. Applicants: Alcoa Power Generating Inc. Description: Alcoa Power Generating Inc. submits...

Next Generation Highly Conducting Organic Films Using Novel Donor-Acceptor Molecules for Opto-electronic Applications

DTIC Science & Technology

2010-06-01

addition, a new class of donor molecules was invented in the course of the DRI program. 2.1 Polymer Based Donor-acceptor Material The following work by...average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data...information, including suggestions for reducing the burden, to Department of Defense, Washington Headquarters Services, Directorate for Information

Six Sigma in healthcare delivery.

PubMed

Liberatore, Matthew J

2013-01-01

The purpose of this paper is to conduct a comprehensive review and assessment of the extant Six Sigma healthcare literature, focusing on: application, process changes initiated and outcomes, including improvements in process metrics, cost and revenue. Data were obtained from an extensive literature search. Healthcare Six Sigma applications were categorized by functional area and department, key process metric, cost savings and revenue generation (if any) and other key implementation characteristics. Several inpatient care areas have seen most applications, including admission, discharge, medication administration, operating room (OR), cardiac and intensive care. About 42.1 percent of the applications have error rate as their driving metric, with the remainder focusing on process time (38 percent) and productivity (18.9 percent). While 67 percent had initial improvement in the key process metric, only 10 percent reported sustained improvement. Only 28 percent reported cost savings and 8 percent offered revenue enhancement. These results do not favorably assess Six Sigma's overall effectiveness and the value it offers healthcare. Results are based on reported applications. Future research can include directly surveying healthcare organizations to provide additional data for assessment. Future application should emphasize obtaining improvements that lead to significant and sustainable value. Healthcare staff can use the results to target promising areas. This article comprehensively assesses Six Sigma healthcare applications and impact.

Next generation tools for genomic data generation, distribution, and visualization

PubMed Central

2010-01-01

Background With the rapidly falling cost and availability of high throughput sequencing and microarray technologies, the bottleneck for effectively using genomic analysis in the laboratory and clinic is shifting to one of effectively managing, analyzing, and sharing genomic data. Results Here we present three open-source, platform independent, software tools for generating, analyzing, distributing, and visualizing genomic data. These include a next generation sequencing/microarray LIMS and analysis project center (GNomEx); an application for annotating and programmatically distributing genomic data using the community vetted DAS/2 data exchange protocol (GenoPub); and a standalone Java Swing application (GWrap) that makes cutting edge command line analysis tools available to those who prefer graphical user interfaces. Both GNomEx and GenoPub use the rich client Flex/Flash web browser interface to interact with Java classes and a relational database on a remote server. Both employ a public-private user-group security model enabling controlled distribution of patient and unpublished data alongside public resources. As such, they function as genomic data repositories that can be accessed manually or programmatically through DAS/2-enabled client applications such as the Integrated Genome Browser. Conclusions These tools have gained wide use in our core facilities, research laboratories and clinics and are freely available for non-profit use. See http://sourceforge.net/projects/gnomex/, http://sourceforge.net/projects/genoviz/, and http://sourceforge.net/projects/useq. PMID:20828407

Study of Nonlinear Propagation of Ultrashort Laser Pulses and Its Application to Harmonic Generation

NASA Astrophysics Data System (ADS)

Weerawarne, Darshana L.

Laser filamentation, which is one of the exotic nonlinear optical phenomena, is self-guidance of high-power laser beams due to the dynamic balance between the optical Kerr effect (self-focusing) and other nonlinear effects such as plasma defocusing. It has many applications including supercontinuum generation (SCG), high-order harmonic generation (HHG), lightning guiding, stand-off sensing, and rain making. The main focus of this work is on studying odd-order harmonic generation (HG) (i.e., 3o, 5o, 7o, etc., where o is the angular frequency) in centrosymmetric media while a high-power, ultrashort harmonic-driving pulse undergoes nonlinear propagation such as laser filamentation. The investigation of highly-controversial nonlinear indices of refraction by measuring low-order HG in air is carried out. Furthermore, time-resolved (i.e., pump-probe) experiments and significant harmonic enhancements are presented and a novel HG mechanism based on higher-order nonlinearities is proposed to explain the experimental results. C/C++ numerical simulations are used to solve the nonlinear Schrodinger equation (NLSE) which supports the experimental findings. Another project which I have performed is selective sintering using lasers. Short-pulse lasers provide a fascinating tool for material processing, especially when the conventional oven-based techniques fail to process flexible materials for smart energy/electronics applications. I present experimental and theoretical studies on laser processing of nanoparticle-coated flexible materials, aiming to fabricate flexible electronic devices.

Crack displacement sensing and measurement in concrete using circular grating moire fringes and pattern matching

NASA Astrophysics Data System (ADS)

Chan, H. M.; Yen, K. S.; Ratnam, M. M.

2008-09-01

The moire method has been extensively studied in the past and applied in various engineering applications. Several techniques are available for generating the moire fringes in these applications, which include moire interferometry, projection moire, shadow moire, moire deflectometry etc. Most of these methods use the superposition of linear gratings to generate the moire patterns. The use of non-linear gratings, such as circular, radial and elongated gratings has received less attention from the research community. The potential of non-linear gratings in engineering measurement has been realized in a limited number of applications, such as rotation measurement, measurement of linear displacement, measurement of expansion coefficients of materials and measurement of strain distribution. In this work, circular gratings of different pitch were applied to the sensing and measurement of crack displacement in concrete structures. Gratings of pitch 0.50 mm and 0.55 mm were generated using computer software and attached to two overlapping acrylic plates that were bonded to either side of the crack. The resulting moire patterns were captured using a standard digital camera and compared with a set of reference patterns generated using a precision positioning stage. Using several image pre-processing stages, such as filtering and morphological operations, and pattern matching the magnitude displacements along two orthogonal axes can be detected with a resolution of 0.05 mm.

Hybrid Power Management Program Evaluated Fuel Cell/Ultracapacitor Combinations and Developed Other New Applications

NASA Technical Reports Server (NTRS)

Eichenberg, Dennis J.

2004-01-01

In fiscal year 2003, the continuation of the Hybrid Power Management (HPM) Program through NASA Glenn Research Center's Commercial Technology Office resulted in several new successful applications of this pioneering technology. HPM is the innovative integration of diverse, state-of-the-art power devices in an optimal configuration for space and terrestrial applications. The appropriate application and control of the various power devices significantly improves overall system performance and efficiency. The advanced power devices include ultracapacitors, fuel cells, and photovoltaics. HPM has extremely wide potential, with applications from nanowatts to megawatts--including power generation, transportation systems, biotechnology systems, and space power systems. HPM has the potential to significantly alleviate global energy concerns, improve the environment, and stimulate the economy. Fuel cells provide excellent efficiency and energy density, but do not have good power density. In contrast, ultracapacitors have excellent power density and virtually unlimited cycle life. To improve the power density of the fuel cell, the combination of fuel cells and ultracapacitors was evaluated.

Field test of a practical secure communication network with decoy-state quantum cryptography.

PubMed

Chen, Teng-Yun; Liang, Hao; Liu, Yang; Cai, Wen-Qi; Ju, Lei; Liu, Wei-Yue; Wang, Jian; Yin, Hao; Chen, Kai; Chen, Zeng-Bing; Peng, Cheng-Zhi; Pan, Jian-Wei

2009-04-13

We present a secure network communication system that operated with decoy-state quantum cryptography in a real-world application scenario. The full key exchange and application protocols were performed in real time among three nodes, in which two adjacent nodes were connected by approximate 20 km of commercial telecom optical fiber. The generated quantum keys were immediately employed and demonstrated for communication applications, including unbreakable real-time voice telephone between any two of the three communication nodes, or a broadcast from one node to the other two nodes by using one-time pad encryption.

Impact: a low cost, reconfigurable, digital beamforming common module building block for next generation phased arrays

NASA Astrophysics Data System (ADS)

Paulsen, Lee; Hoffmann, Ted; Fulton, Caleb; Yeary, Mark; Saunders, Austin; Thompson, Dan; Chen, Bill; Guo, Alex; Murmann, Boris

2015-05-01

Phased array systems offer numerous advantages to the modern warfighter in multiple application spaces, including Radar, Electronic Warfare, Signals Intelligence, and Communications. However, a lack of commonality in the underlying technology base for DoD Phased Arrays has led to static systems with long development cycles, slow technology refreshes in response to emerging threats, and expensive, application-specific sub-components. The IMPACT module (Integrated Multi-use Phased Array Common Tile) is a multi-channel, reconfigurable, cost-effective beamformer that provides a common building block for multiple, disparate array applications.

Design strategies and applications of tissue bioadhesives.

PubMed

Mehdizadeh, Mohammadreza; Yang, Jian

2013-03-01

In the past two decades tissue adhesives and sealants have revolutionized bleeding control and wound healing. This paper focuses on existing tissue adhesive design, their structure, functioning mechanism, and their pros and cons in wound management. It also includes the latest advances in the development of new tissue adhesives as well as the emerging applications in regenerative medicine. We expect that this paper will provide insightful discussion on tissue bioadhesive design and lead to innovations for the development of the next generation of tissue bioadhesives and their related biomedical applications. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Non-military microwave applications

NASA Astrophysics Data System (ADS)

Bierman, Howard

1990-04-01

The nonmilitary applications of microwave technology in medicine, communications, and agriculture are discussed. Particular attention is given to a microwave multichannel multipoint video distribution system (a broadcasting system with up to 20 programs drawn from satellites, video tape libraries, and locally generated material); microwaves used in DBS distribution; satellite receivers for data communications; microwave thermography used for early cancer detection, brain temperature measurements, and appendicitis diagnosis; an experimental Doppler radar assembly for guiding robots walking on a factory floor; and an agricultural application where microwaves are used to break down slugs in soil and thus improve potato and grain crops. Schematic diagrams are included.

Development and Performance Analysis of a Photonics-Assisted RF Converter for 5G Applications

NASA Astrophysics Data System (ADS)

Borges, Ramon Maia; Muniz, André Luiz Marques; Sodré Junior, Arismar Cerqueira

2017-03-01

This article presents a simple, ultra-wideband and tunable radiofrequency (RF) converter for 5G cellular networks. The proposed optoelectronic device performs broadband photonics-assisted upconversion and downconversion using a single optical modulator. Experimental results demonstrate RF conversion from DC to millimeter waves, including 28 and 38 GHz that are potential frequency bands for 5G applications. Narrow linewidth and low phase noise characteristics are observed in all generated RF carriers. An experimental digital performance analysis using different modulation schemes illustrates the applicability of the proposed photonics-based device in reconfigurable optical wireless communications.

A Survey of Colormaps in Visualization

PubMed Central

Zhou, Liang; Hansen, Charles D.

2016-01-01

Colormaps are a vital method for users to gain insights into data in a visualization. With a good choice of colormaps, users are able to acquire information in the data more effectively and efficiently. In this survey, we attempt to provide readers with a comprehensive review of colormap generation techniques and provide readers a taxonomy which is helpful for finding appropriate techniques to use for their data and applications. Specifically, we first briefly introduce the basics of color spaces including color appearance models. In the core of our paper, we survey colormap generation techniques, including the latest advances in the field by grouping these techniques into four classes: procedural methods, user-study based methods, rule-based methods, and data-driven methods; we also include a section on methods that are beyond pure data comprehension purposes. We then classify colormapping techniques into a taxonomy for readers to quickly identify the appropriate techniques they might use. Furthermore, a representative set of visualization techniques that explicitly discuss the use of colormaps is reviewed and classified based on the nature of the data in these applications. Our paper is also intended to be a reference of colormap choices for readers when they are faced with similar data and/or tasks. PMID:26513793

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liss, W.; Dybel, M.; West, R.

This report covers the first year's work performed by the Gas Technology Institute and Encorp Inc. under subcontract to the National Renewable Energy Laboratory. The objective of this three-year contract is to develop innovative grid interconnection and control systems. This supports the advancement of distributed generation in the marketplace by making installations more cost-effective and compatible across the electric power and energy management systems. Specifically, the goals are: (1) To develop and demonstrate cost-effective distributed power grid interconnection products and software and communication solutions applicable to improving the economics of a broad range of distributed power systems, including existing, emerging,more » and other power generation technologies. (2) To enhance the features and capabilities of distributed power products to integrate, interact, and provide operational benefits to the electric power and advanced energy management systems. This includes features and capabilities for participating in resource planning, the provision of ancillary services, and energy management. Specific topics of this report include the development of an advanced controller, a power sensing board, expanded communication capabilities, a revenue-grade meter interface, and a case study of an interconnection distributed power system application that is a model for demonstrating the functionalities of the design of the advanced controller.« less

Nanotechnology for aerospace: potential transitions from university research

NASA Astrophysics Data System (ADS)

Agee, Forrest J.

2008-04-01

Nanotechnology is expected to provide the fundamental basis of the next two generations of products and processes. Impacts for applications are already being felt in many fields, and there is interest especially in the aerospace industry, where performance is a major driver of decisions for applications. Four areas are receiving special emphasis in a program aimed at the Air Force's strategic focus on materials. The emphasis includes adaptive coatings and surface engineering, nanoenergetics, electromagnetic sensors, and power generation and storage. Seven universities in Texas have initiated the CONTACT program of focused research including nine projects in the first year, with plans for expansion in subsequent years. This paper discusses the focus, progress, and plans for the second year and opportunities for industry input to the scope and content of the research. A new model for the creation and guidance of research programs for industry is presented. The new approach includes interaction with the aerospace industry and the Air Force that provides a focus for the research. Results to date for the new method and for the research are presented. A discussion of nanoengineering technology transition into the aerospace industry highlights the mechanisms for enhancing the process and for dealing with intellectual property.

Developing a Large Lexical Database for Information Retrieval, Parsing, and Text Generation Systems.

ERIC Educational Resources Information Center

Conlon, Sumali Pin-Ngern; And Others

1993-01-01

Important characteristics of lexical databases and their applications in information retrieval and natural language processing are explained. An ongoing project using various machine-readable sources to build a lexical database is described, and detailed designs of individual entries with examples are included. (Contains 66 references.) (EAM)

Teaching Raster GIS Operations with Spreadsheets.

ERIC Educational Resources Information Center

Raubal, Martin; Gaupmann, Bernhard; Kuhn, Werner

1997-01-01

Defines raster technology in its relationship to geographic information systems and notes that it is typically used with the application of remote sensing techniques and scanning devices. Discusses the role of spreadsheets in a raster model, and describes a general approach based on spreadsheets. Includes six computer-generated illustrations. (MJP)

Electronic Structure Theory | Materials Science | NREL

Science.gov Websites

design and discover materials for energy applications. This includes detailed studies of the physical computing. Key Research Areas Materials by Design NREL leads the U.S. Department of Energy's Center for Next Generation of Materials by Design, which incorporates metastability and synthesizability. Learn more about

Stem cell-derived vascular endothelial cells and their potential application in regenerative medicine

USDA-ARS?s Scientific Manuscript database

Although a 'vascular stem cell' population has not been identified or generated, vascular endothelial and mural cells (smooth muscle cells and pericytes) can be derived from currently known pluripotent stem cell sources, including human embryonic stem cells and induced pluripotent stem cells. We rev...

The Chicago American Indian Community, 1893-1988. Annotated Bibliography and Guide to Sources in Chicago.

ERIC Educational Resources Information Center

Beck, David

This annotated bibliography identifies and describes documentary evidence of Chicago's American Indian population since the 1893 World's Columbian Exposition. Sources include studies and reports generated by Indian community organizations and agencies, community newsletters, newspapers, oral histories, grant applications, personal papers, and…

RESEARCH AND DEMONSTRATION OF ELECTROSPUN NANOFIBER FILTERS: MULTIFUNCTIONAL, CHEMICALLY ACTIVE FILTRATION TECHNOLOGIES FOR SMALL-SCALE WATER TREATMENT SYSTEMS

EPA Science Inventory

This work will provide the production framework for next-generation treatment technologies capable of targeting diverse chemical pollutants over a range of water chemistries and application scales. Tangible outcomes include a wealth of demonstration data and standard operat...

78 FR 14126 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses and Combined Licenses...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-04

..., or other interest in the proceeding; and (4) the possible effect of any decision or order which may... the fuel, the required diesel generator output and the corresponding fuel oil consumption rate..., to expand its scope to include provisions for temperature excursions...

Mathematics Reform Curricula and Special Education: Identifying Intersections and Implications for Practice

ERIC Educational Resources Information Center

Sayeski, Kristin L.; Paulsen, Kim J.

2010-01-01

In many general education classrooms today, teachers are using "reform" mathematics curricula. These curricula emphasize the application of mathematics in real-life contexts and include such practices as collaborative, group problem solving and student-generated algorithms. Students with learning disabilities in the area of mathematics can…

The semantic planetary data system

NASA Technical Reports Server (NTRS)

Hughes, J. Steven; Crichton, Daniel; Kelly, Sean; Mattmann, Chris

2005-01-01

This paper will provide a brief overview of the PDS data model and the PDS catalog. It will then describe the implentation of the Semantic PDS including the development of the formal ontology, the generation of RDFS/XML and RDF/XML data sets, and the buiding of the semantic search application.

Energy and solid/hazardous waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1981-12-01

This report addresses the past and potential future solid and hazardous waste impacts from energy development, and summarizes the major environmental, legislation applicable to solid and hazardous waste generation and disposal. A glossary of terms and acronyms used to describe and measure solid waste impacts of energy development is included. (PSB)

Advanced technology applications for second and third generation coal gasification systems. Appendix

NASA Technical Reports Server (NTRS)

Bradford, R.; Hyde, J. D.; Mead, C. W.

1980-01-01

Sixteen coal conversion processes are described and their projected goals listed. Tables show the reactants used, products derived, typical operating data, and properties of the feed coal. A history of the development of each process is included along with a drawing of the chemical reactor used.

Odor and odorous chemical emissions from animal buildings: part 1 - project overview, collection methods, and quality control

USDA-ARS?s Scientific Manuscript database

Livestock facilities have historically generated public concerns due to their emissions of odorous air and various chemical pollutants. Odor emission factors and identification of principal odorous chemicals are needed to better understand the problem. Applications of odor emission factors include i...

Quantitative profiling of oxylipins through comprehensive lc-ms/ms analysis: Application in cardiac surgery

USDA-ARS?s Scientific Manuscript database

Oxylipins, including eicosanoids, affect a broad range of biological processes, such as the initiation and resolution of inflammation. These compounds, also referred to as lipid mediators, are (non-) enzymatically generated by oxidation of polyunsaturated fatty acids such as arachidonic acid (AA). A...

Research Advances: Paper Batteries, Phototriggered Microcapsules, and Oil-Free Plastic Production

ERIC Educational Resources Information Center

King, Angela G.

2010-01-01

Chemists continue to work at the forefront of materials science research. Recent advances include application of bioengineering to produce plastics from renewable biomass instead of petroleum, generation of paper-based batteries, and development of phototriggerable microcapsules for chemical delivery. In this article, the author provides summaries…

Evaluation of the impact of lime softening waste disposal in natural environments

EPA Science Inventory

Drinking water treatment residues (WTR), generated from the lime softening processes, are commonly reused or disposed of in a number of applications; these include use as a soil amendment or a subsurface fill. Recently questions were posed by the Florida regulatory community on w...

Mechanical Device Traces Parabolas

NASA Technical Reports Server (NTRS)

Soper, Terry A.

1989-01-01

Mechanical device simplifies generation of parabolas of various focal lengths. Based on fundamental geometrical construction of parabola. Constancy of critical total distance enforced by maintaining cable in tension. Applications of device include design of paraboloidal antennas, approximating catenaries on drawings of powerlines or long-wire antennas, and general tracing of parabolas on drawings.

Computer Applications for Alternative Assessment: An Instructional and Organization Dilemma.

ERIC Educational Resources Information Center

Mills, Ed; Brown, John A.

1997-01-01

Describes the possibilities and problems that computer-generated portfolios will soon present to instructors across America. Highlights include the history of portfolio assessment, logistical problems of handling portfolios in the traditional three-ring binder format, use of the zip drive for storage, and software/hardware compatibility problems.…

Mixed Methods in Intervention Research: Theory to Adaptation

ERIC Educational Resources Information Center

Nastasi, Bonnie K.; Hitchcock, John; Sarkar, Sreeroopa; Burkholder, Gary; Varjas, Kristen; Jayasena, Asoka

2007-01-01

The purpose of this article is to demonstrate the application of mixed methods research designs to multiyear programmatic research and development projects whose goals include integration of cultural specificity when generating or translating evidence-based practices. The authors propose a set of five mixed methods designs related to different…

Tenth Workshop for Computational Fluid Dynamic Applications in Rocket Propulsion, part 1

NASA Technical Reports Server (NTRS)

Williams, R. W. (Compiler)

1992-01-01

Experimental and computational fluid dynamic activities in rocket propulsion were discussed. The workshop was an open meeting of government, industry, and academia. A broad number of topics were discussed including computational fluid dynamic methodology, liquid and solid rocket propulsion, turbomachinery, combustion, heat transfer, and grid generation.

ADVANTG An Automated Variance Reduction Parameter Generator, Rev. 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mosher, Scott W.; Johnson, Seth R.; Bevill, Aaron M.

2015-08-01

The primary objective of ADVANTG is to reduce both the user effort and the computational time required to obtain accurate and precise tally estimates across a broad range of challenging transport applications. ADVANTG has been applied to simulations of real-world radiation shielding, detection, and neutron activation problems. Examples of shielding applications include material damage and dose rate analyses of the Oak Ridge National Laboratory (ORNL) Spallation Neutron Source and High Flux Isotope Reactor (Risner and Blakeman 2013) and the ITER Tokamak (Ibrahim et al. 2011). ADVANTG has been applied to a suite of radiation detection, safeguards, and special nuclear materialmore » movement detection test problems (Shaver et al. 2011). ADVANTG has also been used in the prediction of activation rates within light water reactor facilities (Pantelias and Mosher 2013). In these projects, ADVANTG was demonstrated to significantly increase the tally figure of merit (FOM) relative to an analog MCNP simulation. The ADVANTG-generated parameters were also shown to be more effective than manually generated geometry splitting parameters.« less

White light for the fast lane: supercontinuum generation in all-normal dispersion fibers for ultrafast photonics

NASA Astrophysics Data System (ADS)

Heidt, Alexander M.

2014-03-01

This talk will give an overview of the unique properties of supercontinuum generation (SCG) in all-normal dispersion (ANDi) fibers pumped by ultrashort pulses and the possibilities they offer for ultrafast photonics applications. In contrast to their anomalously pumped counterparts, the SCG process in ANDi fibers conserves a single ultrashort pulse in the time domain, completely suppresses soliton formation and decay, and avoids noise-amplifying nonlinear dynamics. The resulting spectra combine the best of both worlds - the broad, more than octave-spanning bandwidths usually associated with anomalous dispersion pumping with the high temporal coherence, pulse-to-pulse stability and well-defined temporal pulse characteristics known from the normal dispersion regime. These characteristics are ideally suited for ultrafast photonics, and I will present application examples including the generation of high quality single-cycle pulses and their amplification, as well as ultrafast spectroscopy. This talk will also explore the exciting new possibilities enabled by extending this approach into the mid-IR spectral region using novel soft glass fiber designs.

Genetic Programming Transforms in Linear Regression Situations

NASA Astrophysics Data System (ADS)

Castillo, Flor; Kordon, Arthur; Villa, Carlos

The chapter summarizes the use of Genetic Programming (GP) inMultiple Linear Regression (MLR) to address multicollinearity and Lack of Fit (LOF). The basis of the proposed method is applying appropriate input transforms (model respecification) that deal with these issues while preserving the information content of the original variables. The transforms are selected from symbolic regression models with optimal trade-off between accuracy of prediction and expressional complexity, generated by multiobjective Pareto-front GP. The chapter includes a comparative study of the GP-generated transforms with Ridge Regression, a variant of ordinary Multiple Linear Regression, which has been a useful and commonly employed approach for reducing multicollinearity. The advantages of GP-generated model respecification are clearly defined and demonstrated. Some recommendations for transforms selection are given as well. The application benefits of the proposed approach are illustrated with a real industrial application in one of the broadest empirical modeling areas in manufacturing - robust inferential sensors. The chapter contributes to increasing the awareness of the potential of GP in statistical model building by MLR.

Emissions & Generation Resource Integrated Database (eGRID), eGRID2010

EPA Pesticide Factsheets

The Emissions & Generation Resource Integrated Database (eGRID) is a comprehensive source of data on the environmental characteristics of almost all electric power generated in the United States. These environmental characteristics include air emissions for nitrogen oxides, sulfur dioxide, carbon dioxide, methane, and nitrous oxide; emissions rates; net generation; resource mix; and many other attributes.eGRID2010 contains the complete release of year 2007 data, as well as years 2005 and 2004 data. Excel spreadsheets, full documentation, summary data, eGRID subregion and NERC region representational maps, and GHG emission factors are included in this data set. The Archived data in eGRID2002 contain years 1996 through 2000 data.For year 2007 data, the first Microsoft Excel workbook, Plant, contains boiler, generator, and plant spreadsheets. The second Microsoft Excel workbook, Aggregation, contains aggregated data by state, electric generating company, parent company, power control area, eGRID subregion, NERC region, and U.S. total levels. The third Microsoft Excel workbook, ImportExport, contains state import-export data, as well as U.S. generation and consumption data for years 2007, 2005, and 2004. For eGRID data for years 2005 and 2004, a user friendly web application, eGRIDweb, is available to select, view, print, and export specified data.

Skel: Generative Software for Producing Skeletal I/O Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Logan, J.; Klasky, S.; Lofstead, J.

2011-01-01

Massively parallel computations consist of a mixture of computation, communication, and I/O. As part of the co-design for the inevitable progress towards exascale computing, we must apply lessons learned from past work to succeed in this new age of computing. Of the three components listed above, implementing an effective parallel I/O solution has often been overlooked by application scientists and was usually added to large scale simulations only when existing serial techniques had failed. As scientists teams scaled their codes to run on hundreds of processors, it was common to call on an I/O expert to implement a set ofmore » more scalable I/O routines. These routines were easily separated from the calculations and communication, and in many cases, an I/O kernel was derived from the application which could be used for testing I/O performance independent of the application. These I/O kernels developed a life of their own used as a broad measure for comparing different I/O techniques. Unfortunately, as years passed and computation and communication changes required changes to the I/O, the separate I/O kernel used for benchmarking remained static no longer providing an accurate indicator of the I/O performance of the simulation making I/O research less relevant for the application scientists. In this paper we describe a new approach to this problem where I/O kernels are replaced with skeletal I/O applications automatically generated from an abstract set of simulation I/O parameters. We realize this abstraction by leveraging the ADIOS middleware's XML I/O specification with additional runtime parameters. Skeletal applications offer all of the benefits of I/O kernels including allowing I/O optimizations to focus on useful I/O patterns. Moreover, since they are automatically generated, it is easy to produce an updated I/O skeleton whenever the simulation's I/O changes. In this paper we analyze the performance of automatically generated I/O skeletal applications for the S3D and GTS codes. We show that these skeletal applications achieve performance comparable to that of the production applications. We wrap up the paper with a discussion of future changes to make the skeletal application better approximate the actual I/O performed in the simulation.« less

Computational performance of Free Mesh Method applied to continuum mechanics problems

PubMed Central

YAGAWA, Genki

2011-01-01

The free mesh method (FMM) is a kind of the meshless methods intended for particle-like finite element analysis of problems that are difficult to handle using global mesh generation, or a node-based finite element method that employs a local mesh generation technique and a node-by-node algorithm. The aim of the present paper is to review some unique numerical solutions of fluid and solid mechanics by employing FMM as well as the Enriched Free Mesh Method (EFMM), which is a new version of FMM, including compressible flow and sounding mechanism in air-reed instruments as applications to fluid mechanics, and automatic remeshing for slow crack growth, dynamic behavior of solid as well as large-scale Eigen-frequency of engine block as applications to solid mechanics. PMID:21558753

Structural materials issues for the next generation fission reactors

NASA Astrophysics Data System (ADS)

Chant, I.; Murty, K. L.

2010-09-01

Generation-IV reactor design concepts envisioned thus far cater to a common goal of providing safer, longer lasting, proliferation-resistant, and economically viable nuclear power plants. The foremost consideration in the successful development and deployment of Gen-W reactor systems is the performance and reliability issues involving structural materials for both in-core and out-of-core applications. The structural materials need to endure much higher temperatures, higher neutron doses, and extremely corrosive environments, which are beyond the experience of the current nuclear power plants. Materials under active consideration for use in different reactor components include various ferritic/martensitic steels, austenitic stainless steels, nickel-base superalloys, ceramics, composites, etc. This article addresses the material requirements for these advanced fission reactor types, specifically addressing structural materials issues depending on the specific application areas.

Continuous-wave, single-frequency 229  nm laser source for laser cooling of cadmium atoms.

PubMed

Kaneda, Yushi; Yarborough, J M; Merzlyak, Yevgeny; Yamaguchi, Atsushi; Hayashida, Keitaro; Ohmae, Noriaki; Katori, Hidetoshi

2016-02-15

Continuous-wave output at 229 nm for the application of laser cooling of Cd atoms was generated by the fourth harmonic using two successive second-harmonic generation stages. Employing a single-frequency optically pumped semiconductor laser as a fundamental source, 0.56 W of output at 229 nm was observed with a 10-mm long, Brewster-cut BBO crystal in an external cavity with 1.62 W of 458 nm input. Conversion efficiency from 458 nm to 229 nm was more than 34%. By applying a tapered amplifier (TA) as a fundamental source, we demonstrated magneto-optical trapping of all stable Cd isotopes including isotopes Cd111 and Cd113, which are applicable to optical lattice clocks.

Real-time fuzzy inference based robot path planning

NASA Technical Reports Server (NTRS)

Pacini, Peter J.; Teichrow, Jon S.

1990-01-01

This project addresses the problem of adaptive trajectory generation for a robot arm. Conventional trajectory generation involves computing a path in real time to minimize a performance measure such as expended energy. This method can be computationally intensive, and it may yield poor results if the trajectory is weakly constrained. Typically some implicit constraints are known, but cannot be encoded analytically. The alternative approach used here is to formulate domain-specific knowledge, including implicit and ill-defined constraints, in terms of fuzzy rules. These rules utilize linguistic terms to relate input variables to output variables. Since the fuzzy rulebase is determined off-line, only high-level, computationally light processing is required in real time. Potential applications for adaptive trajectory generation include missile guidance and various sophisticated robot control tasks, such as automotive assembly, high speed electrical parts insertion, stepper alignment, and motion control for high speed parcel transfer systems.

Application of exergetic sustainability index to a nano-scale irreversible Brayton cycle operating with ideal Bose and Fermi gasses

NASA Astrophysics Data System (ADS)

Açıkkalp, Emin; Caner, Necmettin

2015-09-01

In this study, a nano-scale irreversible Brayton cycle operating with quantum gasses including Bose and Fermi gasses is researched. Developments in the nano-technology cause searching the nano-scale machines including thermal systems to be unavoidable. Thermodynamic analysis of a nano-scale irreversible Brayton cycle operating with Bose and Fermi gasses was performed (especially using exergetic sustainability index). In addition, thermodynamic analysis involving classical evaluation parameters such as work output, exergy output, entropy generation, energy and exergy efficiencies were conducted. Results are submitted numerically and finally some useful recommendations were conducted. Some important results are: entropy generation and exergetic sustainability index are affected mostly for Bose gas and power output and exergy output are affected mostly for the Fermi gas by x. At the high temperature conditions, work output and entropy generation have high values comparing with other degeneracy conditions.

CometQuest: A Rosetta Adventure

NASA Technical Reports Server (NTRS)

Leon, Nancy J.; Fisher, Diane K.; Novati, Alexander; Chmielewski, Artur B.; Fitzpatrick, Austin J.; Angrum, Andrea

2012-01-01

This software is a higher-performance implementation of tiled WMS, with integral support for KML and time-varying data. This software is compliant with the Open Geospatial WMS standard, and supports KML natively as a WMS return type, including support for the time attribute. Regionated KML wrappers are generated that match the existing tiled WMS dataset. Ping and JPG formats are supported, and the software is implemented as an Apache 2.0 module that supports a threading execution model that is capable of supporting very high request rates. The module intercepts and responds to WMS requests that match certain patterns and returns the existing tiles. If a KML format that matches an existing pyramid and tile dataset is requested, regionated KML is generated and returned to the requesting application. In addition, KML requests that do not match the existing tile datasets generate a KML response that includes the corresponding JPG WMS request, effectively adding KML support to a backing WMS server.

Tiled WMS/KML Server V2

NASA Technical Reports Server (NTRS)

Plesea, Lucian

2012-01-01

This software is a higher-performance implementation of tiled WMS, with integral support for KML and time-varying data. This software is compliant with the Open Geospatial WMS standard, and supports KML natively as a WMS return type, including support for the time attribute. Regionated KML wrappers are generated that match the existing tiled WMS dataset. Ping and JPG formats are supported, and the software is implemented as an Apache 2.0 module that supports a threading execution model that is capable of supporting very high request rates. The module intercepts and responds to WMS requests that match certain patterns and returns the existing tiles. If a KML format that matches an existing pyramid and tile dataset is requested, regionated KML is generated and returned to the requesting application. In addition, KML requests that do not match the existing tile datasets generate a KML response that includes the corresponding JPG WMS request, effectively adding KML support to a backing WMS server.

Evolutionary Maps: A new model for the analysis of conceptual development, with application to the diurnal cycle

NASA Astrophysics Data System (ADS)

Navarro, Manuel

2014-05-01

This paper presents a model of how children generate concrete concepts from perception through processes of differentiation and integration. The model informs the design of a novel methodology (evolutionary maps or emaps), whose implementation on certain domains unfolds the web of itineraries that children may follow in the construction of concrete conceptual knowledge and pinpoints, for each conception, the architecture of the conceptual change that leads to the scientific concept. Remarkably, the generative character of its syntax yields conceptions that, if unknown, amount to predictions that can be tested experimentally. Its application to the diurnal cycle (including the sun's trajectory in the sky) indicates that the model is correct and the methodology works (in some domains). Specifically, said emap predicts a number of exotic trajectories of the sun in the sky that, in the experimental work, were drawn spontaneously both on paper and a dome. Additionally, the application of the emaps theoretical framework in clinical interviews has provided new insight into other cognitive processes. The field of validity of the methodology and its possible applications to science education are discussed.

40 CFR 1039.627 - What are the incentives for equipment manufacturers to use cleaner engines?

Code of Federal Regulations, 2011 CFR

2011-07-01

... generator sets and how many you install in other applications under the provisions of this section. Offsets from generator-set engines may be used only for generator-set engines. Offsets from engines for other applications may be used only for other applications besides generator sets. (d) Reporting. When you submit...

40 CFR 1039.627 - What are the incentives for equipment manufacturers to use cleaner engines?

Code of Federal Regulations, 2010 CFR

2010-07-01

... generator sets and how many you install in other applications under the provisions of this section. Offsets from generator-set engines may be used only for generator-set engines. Offsets from engines for other applications may be used only for other applications besides generator sets. (d) Reporting. When you submit...

Aerospace Applications of Non-Equilibrium Plasma

NASA Technical Reports Server (NTRS)

Blankson, Isaiah M.

2016-01-01

Nonequilibrium plasma/non-thermal plasma/cold plasmas are being used in a wide range of new applications in aeronautics, active flow control, heat transfer reduction, plasma-assisted ignition and combustion, noise suppression, and power generation. Industrial applications may be found in pollution control, materials surface treatment, and water purification. In order for these plasma processes to become practical, efficient means of ionization are necessary. A primary challenge for these applications is to create a desired non-equilibrium plasma in air by preventing the discharge from transitioning into an arc. Of particular interest is the impact on simulations and experimental data with and without detailed consideration of non-equilibrium effects, and the consequences of neglecting non-equilibrium. This presentation will provide an assessment of the presence and influence of non-equilibrium phenomena for various aerospace needs and applications. Specific examples to be considered will include the forward energy deposition of laser-induced non-equilibrium plasmoids for sonic boom mitigation, weakly ionized flows obtained from pulsed nanosecond discharges for an annular Hall type MHD generator duct for turbojet energy bypass, and fundamental mechanisms affecting the design and operation of novel plasma-assisted reactive systems in dielectric liquids (water purification, in-pipe modification of fuels, etc.).

System for generating a beam of acoustic energy from a borehole, and applications thereof

DOEpatents

Vu, Cung Khac; Sinha, Dipen N.; Pantea, Cristian; Nihei, Kurt T.; Schmitt, Denis P.; Skelt, Christopher

2012-09-04

In some aspects of the invention, a device, positioned within a well bore, configured to generate and direct an acoustic beam into a rock formation around a borehole is disclosed. The device comprises a source configured to generate a first signal at a first frequency and a second signal at a second frequency; a transducer configured to receive the generated first and the second signals and produce acoustic waves at the first frequency and the second frequency; and a non-linear material, coupled to the transducer, configured to generate a collimated beam with a frequency equal to the difference between the first frequency and the second frequency by a non-linear mixing process, wherein the non-linear material includes one or more of a mixture of liquids, a solid, a granular material, embedded microspheres, or an emulsion.

System for generating a beam of acoustic energy from a borehole, and applications thereof

DOEpatents

Vu, Cung Khac [Houston, TX; Sinha, Dipen N [Los Alamos, NM; Pantea, Cristian [Los Alamos, NM; Nihei, Kurt T [Oakland, CA; Schmitt, Denis P [Katy, TX; Skelt, Christopher [Houston, TX

2012-07-31

In some aspects of the invention, a device, positioned within a well bore, configured to generate and direct an acoustic beam into a rock formation around a borehole is disclosed. The device comprises a source configured to generate a first signal at a first frequency and a second signal at a second frequency; a transducer configured to receive the generated first and the second signals and produce acoustic waves at the first frequency and the second frequency; and a non-linear material, coupled to the transducer, configured to generate a collimated beam with a frequency equal to the difference between the first frequency and the second frequency by a non-linear mixing process, wherein the non-linear material includes one or more of a mixture of liquids, a solid, a granular material, embedded microspheres, or an emulsion.

Metallic nanoislands on graphene: A metamaterial for chemical, mechanical, optical, and biological applications.

PubMed

Marin, Brandon C; Ramirez, Julian; Root, Samuel E; Aklile, Eden; Lipomi, Darren J

2017-01-01

Graphene decorated with metallic nanoparticles exhibits electronic, optical, and mechanical properties that neither the graphene nor the metal possess alone. These composite films have electrical conductivity and optical properties that can be modulated by a range of physical, chemical, and biological signals. Such properties are controlled by the morphology of the nanoisland films, which can be deposited on graphene using a variety of techniques, including in situ chemical synthesis and physical vapor deposition. These techniques produce non-random (though loosely defined) morphologies, but can be combined with lithography to generate deterministic patterns. Applications of these composite films include chemical sensing and catalysis, energy storage and transport (including photoconductivity), mechanical sensing (using a highly sensitive piezroresistive effect), optical sensing (including so-called "piezoplasmonic" effects), and cellular biophysics (i.e sensing the contractions of cardiomyocytes and myoblasts).

Nondestructive Evaluation Approaches Developed for Material Characterization in Aeronautics and Space Applications

NASA Technical Reports Server (NTRS)

Baaklini, George Y.; Kautz, Harold E.; Gyekenyesi, Andrew L.; Abdul-Aziz, Ali; Martin, Richard E.

2001-01-01

At the NASA Glenn Research Center, nondestructive evaluation (NDE) approaches were developed or tailored for characterizing advanced material systems. The emphasis was on high-temperature aerospace propulsion applications. The material systems included monolithic ceramics, superalloys, and high-temperature composites. In the aeronautics area, the major applications were cooled ceramic plate structures for turbine applications, gamma-TiAl blade materials for low-pressure turbines, thermoelastic stress analysis for residual stress measurements in titanium-based and nickel-based engine materials, and acousto-ultrasonics for creep damage assessment in nickel-based alloys. In the space area, applications consisted of cooled carbon-carbon composites for gas generator combustors and flywheel rotors composed of carbon-fiber-reinforced polymer matrix composites for energy storage on the International Space Station.

Microbial fuel cells for biosensor applications.

PubMed

Yang, Huijia; Zhou, Minghua; Liu, Mengmeng; Yang, Weilu; Gu, Tingyue

2015-12-01

Microbial fuel cells (MFCs) face major hurdles for real-world applications as power generators with the exception of powering small sensor devices. Despite tremendous improvements made in the last two decades, MFCs are still too expensive to build and operate and their power output is still too small. In view of this, in recently years, intensive researches have been carried out to expand the applications into other areas such as acid and alkali production, bioremediation of aquatic sediments, desalination and biosensors. Unlike power applications, MFC sensors have the immediate prospect to be practical. This review covers the latest developments in various proposed biosensor applications using MFCs including monitoring microbial activity, testing biochemical oxygen demand, detection of toxicants and detection of microbial biofilms that cause biocorrosion.

Investigation of self-excited induction generators for wind turbine applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muljadi, E.; Butterfield, C.P.; Sallan, J.

2000-02-28

The use of squirrel-cage induction machines in wind generation is widely accepted as a generator of choice. The squirrel-cage induction machine is simple, reliable, cheap, lightweight, and requires very little maintenance. Generally, the induction generator is connected to the utility at constant frequency. With a constant frequency operation, the induction generator operates at practically constant speed (small range of slip). The wind turbine operates in optimum efficiency only within a small range of wind speed variation. The variable-speed operation allows an increase in energy captured and reduces both the torque peaks in the drive train and the power fluctuations sentmore » to the utility. In variable-speed operation, an induction generator needs an interface to convert the variable frequency output of the generator to the fixed frequency at the utility. This interface can be simplified by using a self-excited generator because a simple diode bridge is required to perform the ac/dc conversion. The subsequent dc/ac conversion can be performed using different techniques. The use of a thyristor bridge is readily available for large power conversion and has a lower cost and higher reliability. The firing angle of the inverter bridge can be controlled to track the optimum power curve of the wind turbine. With only diodes and thyristors used in power conversion, the system can be scaled up to a very high voltage and high power applications. This paper analyzes the operation of such a system applied to a 1/3-hp self-excited induction generator. It includes the simulations and tests performed for the different excitation configurations.« less

RCRA Part A Permit Application for Waste Management Activities at the Nevada Test Site, Part B Permit Application Hazardous Waste Storage Unit, Nevada Test Site, and Part B Permit Application - Explosives Ordnance Disposal Unit (EODU)

DOE Office of Scientific and Technical Information (OSTI.GOV)

NSTec Environmental Programs

2010-06-17

The Area 5 Hazardous Waste Storage Unit (HWSU) was established to support testing, research, and remediation activities at the Nevada Test Site (NTS), a large-quantity generator of hazardous waste. The HWSU, located adjacent to the Area 5 Radioactive Waste Management Site (RWMS), is a prefabricated, rigid steel-framed, roofed shelter used to store hazardous nonradioactive waste generated on the NTS. No offsite generated wastes are managed at the HWSU. Waste managed at the HWSU includes the following categories: Flammables/Combustibles; Acid Corrosives; Alkali Corrosives; Oxidizers/Reactives; Toxics/Poisons; and Other Regulated Materials (ORMs). A list of the regulated waste codes accepted for storage atmore » the HWSU is provided in Section B.2. Hazardous wastes stored at the HWSU are stored in U.S. Department of Transportation (DOT) compliant containers, compatible with the stored waste. Waste transfer (between containers) is not allowed at the HWSU and containers remain closed at all times. Containers are stored on secondary containment pallets and the unit is inspected monthly. Table 1 provides the metric conversion factors used in this application. Table 2 provides a list of existing permits. Table 3 lists operational Resource Conservation and Recovery Act (RCRA) units at the NTS and their respective regulatory status.« less

Progress In Optical Memory Technology

NASA Astrophysics Data System (ADS)

Tsunoda, Yoshito

1987-01-01

More than 20 years have passed since the concept of optical memory was first proposed in 1966. Since then considerable progress has been made in this area together with the creation of completely new markets of optical memory in consumer and computer application areas. The first generation of optical memory was mainly developed with holographic recording technology in late 1960s and early 1970s. Considerable number of developments have been done in both analog and digital memory applications. Unfortunately, these technologies did not meet a chance to be a commercial product. The second generation of optical memory started at the beginning of 1970s with bit by bit recording technology. Read-only type optical memories such as video disks and compact audio disks have extensively investigated. Since laser diodes were first applied to optical video disk read out in 1976, there have been extensive developments of laser diode pick-ups for optical disk memory systems. The third generation of optical memory started in 1978 with bit by bit read/write technology using laser diodes. Developments of recording materials including both write-once and erasable have been actively pursued at several research institutes. These technologies are mainly focused on the optical memory systems for computer application. Such practical applications of optical memory technology has resulted in the creation of such new products as compact audio disks and computer file memories.

Slot-Antenna/Permanent-Magnet Device for Generating Plasma

NASA Technical Reports Server (NTRS)

Foster, John E.

2007-01-01

A device that includes a rectangular-waveguide/slot-antenna structure and permanent magnets has been devised as a means of generating a substantially uniform plasma over a relatively large area, using relatively low input power and a low gas flow rate. The device utilizes electron cyclotron resonance (ECR) excited by microwave power to efficiently generate plasma in a manner that is completely electrodeless in the sense that, in principle, there is no electrical contact between the plasma and the antenna. Plasmas generated by devices like this one are suitable for use as sources of ions and/or electrons for diverse material-processing applications (e.g., etching or deposition) and for ion thrusters. The absence of plasma/electrode contact essentially prevents plasma-induced erosion of the antenna, thereby also helping to minimize contamination of the plasma and of objects exposed to the plasma. Consequently, the operational lifetime of the rectangular-waveguide/ slot-antenna structure is long and the lifetime of the plasma source is limited by the lifetime of the associated charged-particle-extraction grid (if used) or the lifetime of the microwave power source. The device includes a series of matched radiating slot pairs that are distributed along the length of a plasma-source discharge chamber (see figure). This arrangement enables the production of plasma in a distributed fashion, thereby giving rise to a uniform plasma profile. A uniform plasma profile is necessary for uniformity in any electron- or ion-extraction electrostatic optics. The slotted configuration of the waveguide/ antenna structure makes the device scalable to larger areas and higher powers. All that is needed for scaling up is the attachment of additional matched radiating slots along the length of the discharge chamber. If it is desired to make the power per slot remain constant in scaling up, then the input microwave power must be increased accordingly. Unlike in prior ECR microwave plasma-generating devices, there is no need for an insulating window on the antenna. Such windows are sources of contamination and gradually become ineffective as they become coated with erosion products over time. These characteristics relegate prior ECR microwave plasma-generating devices to non-ion beam, non-deposition plasma applications. In contrast, the lack of need for an insulating window in the present device makes it possible to use the device in both ion-beam (including deposition) and electron-beam applications. The device is designed so that ECR takes place above each slot and the gradient of the magnetic field at each slot is enough to prevent backflow of plasma.

Fabrication and Performance of Zirconia Electrolysis Cells for Carbon Dioxide Reduction for Mars In Situ Resource Utilization Applications

NASA Technical Reports Server (NTRS)

Minh, N. Q.; Chung, B. W.; Doshi, R.; Lear, G. R.; Montgomery, K.; Ong, E. T.

1999-01-01

The use of the Martian atmosphere (95% CO2) to produce oxygen (for propellant and life support) can significantly lower the required launch mass and dramatically reduce the total cost for Mars missions. Zirconia electrolysis cells are one of the technologies being considered for oxygen generation from carbon dioxide in Mars In Situ Resource Utilization (ISRU) production plants. The attractive features of the zirconia cell for this application include simple operation and lightweight, low volume system.

Updates to the QBIC system

NASA Astrophysics Data System (ADS)

Niblack, Carlton W.; Zhu, Xiaoming; Hafner, James L.; Breuel, Tom; Ponceleon, Dulce B.; Petkovic, Dragutin; Flickner, Myron D.; Upfal, Eli; Nin, Sigfredo I.; Sull, Sanghoon; Dom, Byron E.; Yeo, Boon-Lock; Srinivasan, Savitha; Zivkovic, Dan; Penner, Mike

1997-12-01

QBICTM (Query By Image Content) is a set of technologies and associated software that allows a user to search, browse, and retrieve image, graphic, and video data from large on-line collections. This paper discusses current research directions of the QBIC project such as indexing for high-dimensional multimedia data, retrieval of gray level images, and storyboard generation suitable for video. It describes aspects of QBIC software including scripting tools, application interfaces, and available GUIs, and gives examples of applications and demonstration systems using it.

Amazonas project: Application of remote sensing techniques for the integrated survey of natural resources in Amazonas. [Brazil

NASA Technical Reports Server (NTRS)

Dejesusparada, N. (Principal Investigator)

1981-01-01

The use of LANDSAT multispectral scanner and return beam vidicon imagery for surveying the natural resources of the Brazilian Amazonas is described. Purposes of the Amazonas development project are summarized. The application of LANDSAT imagery to identification of vegetation coverage and soil use, identification of soil types, geomorphology, and geology and highway planning is discussed. An evaluation of the worth of LANDSAT imagery in mapping the region is presented. Maps generated by the project are included.

Novel diode laser-based sensors for gas sensing applications

NASA Technical Reports Server (NTRS)

Tittel, F. K.; Lancaster, D. G.; Richter, D.

2000-01-01

The development of compact spectroscopic gas sensors and their applications to environmental sensing will be described. These sensors employ mid-infrared difference-frequency generation (DFG) in periodically poled lithium niobate (PPLN) crystals pumped by two single-frequency solid state lasers such as diode lasers, diode-pumped solid state, and fiber lasers. Ultrasensitive, highly selective, and real-time measurements of several important atmospheric trace gases, including carbon monoxide, nitrous oxide, carbon dioxide, formaldehyde [correction of formaldehye], and methane, have been demonstrated.

Binomial test statistics using Psi functions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bowman, Kimiko o

2007-01-01

For the negative binomial model (probability generating function (p + 1 - pt){sup -k}) a logarithmic derivative is the Psi function difference {psi}(k + x) - {psi}(k); this and its derivatives lead to a test statistic to decide on the validity of a specified model. The test statistic uses a data base so there exists a comparison available between theory and application. Note that the test function is not dominated by outliers. Applications to (i) Fisher's tick data, (ii) accidents data, (iii) Weldon's dice data are included.

A Guide to Using STITCHER for Overlapping Assembly PCR Applications.

PubMed

O'Halloran, Damien M

2017-01-01

Overlapping PCR is commonly used in many molecular applications that include stitching PCR fragments together, generating fluorescent transcriptional and translational fusions, inserting mutations, making deletions, and PCR cloning. Overlapping PCR is also used for genotyping and in detection experiments using techniques such as loop-mediated isothermal amplification (LAMP). STITCHER is a web tool providing a central resource for researchers conducting all types of overlapping assembly PCR experiments with an intuitive interface for automated primer design that's fast, easy to use, and freely available online.

Transonic Symposium: Theory, Application, and Experiment, volume 1, part 2

NASA Technical Reports Server (NTRS)

Foughner, Jerome T., Jr. (Compiler)

1989-01-01

In order to assess the state of the art in transonic flow disciplines and to glimpse at future directions, NASA-Langley held a Transonic Symposium. Emphasis was placed on steady, three dimensional external, transonic flow and its simulation, both numerically and experimentally. The symposium included technical sessions on wind tunnel and flight experiments; computational fluid dynamic applications; inviscid methods and grid generation; viscous methods and boundary layer stability; and wind tunnel techniques and wall interference. This, being volume 1, is unclassified.

Mathematical modeling in biological populations through branching processes. Application to salmonid populations.

PubMed

Molina, Manuel; Mota, Manuel; Ramos, Alfonso

2015-01-01

This work deals with mathematical modeling through branching processes. We consider sexually reproducing animal populations where, in each generation, the number of progenitor couples is determined in a non-predictable environment. By using a class of two-sex branching processes, we describe their demographic dynamics and provide several probabilistic and inferential contributions. They include results about the extinction of the population and the estimation of the offspring distribution and its main moments. We also present an application to salmonid populations.

Microfluidics for Drug Discovery and Development: From Target Selection to Product Lifecycle Management

PubMed Central

Kang, Lifeng; Chung, Bong Geun; Langer, Robert; Khademhosseini, Ali

2009-01-01

Microfluidic technologies’ ability to miniaturize assays and increase experimental throughput have generated significant interest in the drug discovery and development domain. These characteristics make microfluidic systems a potentially valuable tool for many drug discovery and development applications. Here, we review the recent advances of microfluidic devices for drug discovery and development and highlight their applications in different stages of the process, including target selection, lead identification, preclinical tests, clinical trials, chemical synthesis, formulations studies, and product management. PMID:18190858

Practical application of pulsed "eye-safe" microchip laser to laser rangefinders

NASA Astrophysics Data System (ADS)

Młyńczak, J.; Kopczyński, K.; Mierczyk, Z.; Zygmunt, M.; Natkański, S.; Muzal, M.; Wojtanowski, J.; Kirwil, P.; Jakubaszek, M.; Knysak, P.; Piotrowski, W.; Zarzycka, A.; Gawlikowski, A.

2013-09-01

The paper describes practical application of pulsed microchip laser generating at 1535-nm wavelength to a laser rangefinder. The complete prototype of a laser rangefinder was built and investigated in real environmental conditions. The measured performance of the device is discussed. To build the prototype of a laser rangefinder at a reasonable price and shape a number of basic considerations had to be done. These include the mechanical and optical design of a microchip laser and the opto-mechanical construction of the rangefinder.

Initial animal studies of a wireless, batteryless, MEMS implant for cardiovascular applications.

PubMed

Najafi, Nader; Ludomirsky, Achiau

2004-03-01

This paper reports the results of the initial animal studies of a wireless, batteryless, implantable pressure sensor using microelectromechanical systems (MEMS) technology. The animal studies were acute and proved the functional feasibility of using MEMS technology for wireless bio sensing. The results are very encouraging and surpassed the majority of the application's requirements, including high sampling speed and high resolution. Based on the lessons learned, second generation wireless sensors are being developed that will provide total system solution.